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  • Book
    [edited by] Brigitte Wildemann, Patrick Oschmann, Hansotto Reiber ; with contributions by J. Brettschneider [and others].
    Summary: "Up-to-date, comprehensive, and beautifully illustrated, Laboratory Diagnosis in Neurology presents all the measuring parameters and methods relevant to the analysis of cerebrospinal fluid, serum, and tissues affected by neurologic disease and syndromes. Following an introduction to basic concepts, the book guides clinicians through the methods of CSF analysis, neurochemical examinations, clinical applications of neuroimmunology, microbiology and virology, neurogenetic tests, and evaluation of biopsies. Readers will learn about the equipment and various procedures, and how to effectively differentiate similar methods. In the final section of the book, the authors provide a systematic introduction to the pathophysiology and laboratory findings for specific clinical disorders, indications for particular test methods, and criteria for diagnostic interpretation"--Provided by publisher.

    Contents:
    Cerebrospinal fluid: spaces, production, and flow / H. Reiber
    Blood-brain barrier and blood-CSF barrier function / H. Reiber
    Blood-brain barrier
    The blood-CSF barrier function
    Dynamics of serum and brain proteins in CSF and blood / H. Reiber
    Serum proteins in CSF
    Brain proteins in CSF
    Brain proteins in blood
    Principles of analytical methods / H. Reiber Immunochemistry
    Qualitative electrophoretic methods with or without immunodetection
    Immunohistochemistry
    Cerebrospinal fluid analysis / B. Storch-Hagenlocher ... [et al.]
    Cerebrospinal puncture / B. Storch-Hagenlocher
    Measurement of cerebrospinal pressure / B. Storch-Hagenlocher
    Cell count, cytology / B. Storch-Hagenlocher Proteins / H. Reiber
    Lactate and glucose / H. Reiber
    Diagnosis of pathogens / B. Wildemann, H.K. Geiss, P. Schnitzler
    Markers of dementia and neuronal destruction / M. Otto
    Serum analysis / M. Zorn, M. Uhr
    General serum analysis / M. Zorn
    Special serum analysis / M. Uhr
    Autoantibodies and antineural antibodies / B. Wildemann, U. Wurster
    Autoantibodies / B. Wildemann
    Antineural antibodies / U. Wurster
    Neurogenetics / T. Gasser
    Monogenic hereditary neurological disorders
    Polygenic or multifactorial hereditary neurological disorders
    Biopsy / A. Rosenbohm, A. Sperfeld, H. Tumani
    Brain biopsy
    Nerve biopsy
    Music biopsy
    Inflammatory and autoimmune diseases / B. Storch-Hagenlocher, P. Oschmann, B. Wildemann
    Infections
    Non-pathogen-related inflammatory disorders: autoimmune diseases
    Dementia and other psychiatric disorders / M. Otto, M. Uhr
    Alzheimer's disease / M. Otto
    Lewy body dementia / M. Otto
    Frontotemporal lobar degeneration / M. Otto
    Multiple system atrophy / M. Otto
    Subcortical arteriosclerotic encephalopathy / M. Otto
    Creutzfeldt-Jakob disease / M. Otto
    Psychiatric disorders / M. Uhr
    Cerebral ischemia and hemorrhage / E. Stolz, P. Oschmann
    Ischemic cerebral infarction
    Intracerebral hemorrhage
    Subarachnoid hemorrhage
    Cerebral hypoxia
    Polyneuropathies / B. Wildemann
    Pseudotumor cerebri, ventricular drainage, and neurosurgery / E. Stolz, P. Oschmann
    Pseudotumor cerebri
    External ventricular drainage, ventriculoatrial and ventriculoperitoneal shunts
    Diagnosis of cerebrospinal rhinorrhea and otorrhea
    Epileptic seizures / J. Brettschneider, H. Tumani
    Brain tumors / B. Storch-Hagenlocher, M. Vogt-Schaden
    Primary brain tumors / B. Storch-Hagenlocher
    Secondary brain tumors / M. Vogt-Schaden
    Neoplastic meaningitis in malignant non-hodgkin lymphoma and leukemia / M. Vogt-Schaden
    Metabolic diseases / F. Ebinger
    Mitochondrial diseases
    Lysosomal diseases
    Peroxisomal diseases
    Cerebrotendinous xanthomatosis
    Leukodystrophy/leukoencephalopathy in organic aciduria
    Disorders of copper metabolism
    Parasitoses and tropical diseases / H. Reiber, E. Schmutzhard
    CSF analysis report / H. Reiber
    Integrated CSF report
    CSF analysis procedure
    Evaluation
    Interpretation
    Quality assessment in the CSF laboratory / H. Reiber
    Quality assessment in laboratory medicine
    Internal quality control for CSF proteins (total protein, albumin, IgG, IgA, IgM)
    The INSTAND interlaboratory CSF survey
    CSF survey : lactate, glucose and surrogate markers
    CSF cytology : quality control and interpretation training
    Reference ranges of analytes in CSF and serum / H. Reiber
    Electrolytes and substrates
    Proteins
    Amino acides, lipids, and vitamins
    Cells.