BookNima Rezaei, editor.
Summary: This translational book describes in detail the clinical application of novel approaches in cancer immunotherapy with the aim of educating clinicians in the implications of the most recent research and new developments in the field. The scope is broad, encompassing, for example, prognostic biomarkers for personalized cancer treatment, strategies for targeting tumor immunosuppression, gene therapy, virus-based vaccines, targeting of cancer stem cells, hematopoietic stem cell transplantation, the role of T lymphocytes in cancer immunotherapy, use of monoclonal antibodies, and many more innovative approaches. Clinical immunologists, hematologists, and oncologists in particular will find the book to be of value in expanding their knowledge. ℗ℓ The book is the second in a three-volume series, Cancer Immunology, which offers an up-to-date review of cancer immunology and immunotherapy. The remaining volumes focus on the immunopathology of cancers and cancer immunotherapy for organ-specific tumors. In total the series, designed for both clinicians and researchers, includes contributions from more than 250 scientists working at leading universities and institutes from across the world.
Contents:
Frontiers in Cancer Immunotherapy
Novel Strategy of Cancer Immunotherapy: Spiraling Up
Novel Prognostic Biomarkers for Personalized Cancer Treatments
Tumor Antigen and Epitope Identification for Pre-Clinical and Clinical Evaluation
Strategies to Target Tumor Immunesuppression
Immune Modulation of Drugs in Prevention and Treatment of Cancers
Overcoming Immune Tolerance With Immune Checkpoint Blockade
Gene therapy and Virus-Based Cancer Vaccines
Cancer Stem Cells: Biology and Potential therapeutic Applications
Hematopoietic Stem Cell Transplantation and Lymphodepletion in Treatment of Cancers
Combination of Chemotherapy and Cytokine Therapy in Treatment of Cancers
T Cell Immunotherapy: From Synthetic Biology to Clinical Practice
Role of Gamma-Delta T Lymphocytes in Cancer Immunosurveillance and Immunotherapy
Adoptive T Cell therapy: Optimizing Chemokine Receptor-Mediated Homing of T Cells in Cancer Immunotherapy
Cellular therapy of Cancer With B Effector Cells
Monoclonal Antibodies for Treatment of Cancers
Pattern Recognition Receptors in Cancers and Immunotherapy by Triggering or Targeting of Toll Like Receptors Pathway
Recent Advances in the Use of NK Cells Against Cancer
Dendritic Cell Vaccines for Cancer Therapy: Fundamentals and Clinical Trials
Tumor Associated Macrophages and iNOS in Cancer Immunotherapy
Photodynamic therapy and Anti-Tumor Immune Response
Polarization of Tumor Milieu: Therapeutic Implications
Immunotherapies Targeting 5T4 Oncofoetal Glycoprotein
Immune Monitoring During Clinical Development of Anti-CTLA-4 Antibody Therapy
PD-1 Blockade in Cancer Therapy
New Advances in Radioimmunotherapy for the Treatment of Cancers
Psychoneuroendocrinoimmunotherapy of Cancers
Ethical Considerations in Cancer Immunotherapy.