BookAndrew J. Dannenberg, Nathan A. Berger, editors.
Summary: In addition to their metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with chronic low grade inflammation resulting in cellular and humoral factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. Obesity, Inflammation and Cancer focuses on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. It also describes possible strategies for targeting inflammation as an approach to cancer prevention and control. Students, researchers and clinicians, especially those interested in the relation of obesity to cancer and the role of inflammation and its impact on cancer, will find this volume particularly useful. It provides important insight on the role of inflammation in cancer etiology and progression and serve as a platform for developing future research in this area.
Contents:
Obesity, Inflammation, and Insulin Resistance / Lesley G. Ellies, Andrew Johnson
Inflammasomes and Obesity / Tuo Deng, Jun Cui
Uncoupling Obesity from Cancer: Bromodomain Co-regulators That Control Inflammatory Networks / Gerald V. Denis, Deborah J. Bowen
Adipose Tissue Macrophages in Obesity, Inflammation, and Cancer / Carey Nien-Kai Lumeng,
Dietary Fats as Mediators of Obesity, Inflammation, and Colon Cancer / Stephanie K. Doerner, Nathan A. Berger
Inflammation, Obesity, Barrett's Esophagus, and Esophageal Adenocarcinoma / Anamay Sharma, Ahmed Elebiary
Inflammation, Obesity, and Colon Cancer / Stephanie K. Doerner, Jason D. Heaney
Obesity, Inflammation, and Breast Cancer / Neil M. Iyengar, Patrick G. Morris
Obesity, Inflammation, Nonalcoholic Fatty Liver Disease, and Hepatocellular Carcinoma / Naim Alkhouri, Arthur McCullough
Obesity, Inflammation, and Prostate Cancer / Jorge Blando, Achinto Saha, Kaoru Kiguchi
Pharmacologic Interventions with NSAIDs / Louise R. Howe
Omega-3 Fatty Acids in Cancer Prevention and Control: A Membrane Perspective / Harmony F. Turk, Jennifer M. Monk
Natural Products as Anti-inflammatory Agents / Gary Stoner, Li-Shu Wang
Calorie Restriction and Cancer Prevention: Established and Emerging Mechanisms / Stephen D. Hursting, Nikki A. Ford
Vascular Targeting of Adipose Tissue / Ahmad Salameh, Mikhail G. Kolonin
Anti-inflammatory Effects of Exercise / Michael Gleeson.