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  • Book
    volume editor, Lars E. French.
    Summary: "The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1 to 5 percent for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists." -- publisher's site.

    Contents:
    Epidemiology of cutaneous adverse drug reactions / M. Mockenhaupt
    Genetics and the potential for predictive tests in adverse drug reactions / M. Pirmohamed
    Etiology and pathogenesis of adverse drug reactions / O. Hausmann, B. Schnyder and W.J. Pichler
    Diagnostic approach to drug allergy / T. Harr
    Histopathological patterns indicative of distinct adverse drug reactions / K. Kerl
    Uncomplicated drug-induced disseminated exanthemas / A.J. Bircher
    Drug-induced angioedema / M. Lerch
    Fixed drug eruption: the dark side of activation of intraepidermal CD8+ T cells uniquely specialized to mediate protective immunity / T. Shiohara and Y. Mizukawa
    Drug-induced hypersensitivity syndrome: recent advances in the diagnosis, pathogenesis and management / T. Shiohara ... [et al.]
    Acute generalized exanthematous pustulosis / A. Sidoroff
    Stevens-Johnson syndrome and toxic epidermal necrolysis / T. Harr and L.E. French
    Phototoxic and photoallergic cutaneous drug reactions / M. Glatz and G.F. Hofbauer
    Immediate and delayed cutaneous reactions to radiocontrast media / K. Brockow
    Cutaneous drug eruptions associated with the use of new oncological drugs / B. Belloni ... [et al.]
    Cutaneous drug eruptions associated with the use of biologics and cutaneous drug eruptions mimicking specific skin diseases / J. Seneschal, B. Milpied and A. Taieb
    Desensitization for hypersensitivity reactions to medications / M. del Carmen Sancho ... [et al.].
    Digital Access Karger 2012