Bookedited by Anders Björklund, M. Angela Cenci.
Contents:
Section I. Animal models of PD
Chapter 1. What have we learned from Drosophila models of Parkinson's disease? / Ming Guo
Chapter 2. Neurotoxic in vivo models of Parkinson's disease: recent advances / Jason R. Cannon, J. Timothy Greenamyre
Chapter 3. Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease / Stephen B. Dunnett, Mariah Lelos
Chapter 4. Genetic mouse models of Parkinson's disease: The state of the art / Iddo Magen, Marie-Françoise Chesselet
Chapter 5. Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease / Ayse Ulusoy, Mickael Decressac, Deniz Kirik, Anders Björklund
Chapter 6. Modeling neuroinflammatory pathogenesis of Parkinson's disease / Christopher J. Barnum, Malú G. Tansey
Chapter 7. The MPTP-lesioned non-human primate models of Parkinson's disease. Past, present, and future / Susan H. Fox, Jonathan M. Brotchie
Section II. Exploring PD with brain imaging.
Chapter 8. Abnormal metabolic brain networks in Parkinson's disease: from blackboard to bedside / Chris C. Tang, David Eidelberg
Chapter 9. Imaging the nigrostriatal system to monitor disease progression and treatment-induced complications / Renju Kuriakose, A. Jon Stoessl
Chapter 10. Brain imaging after neural transplantation / Marios Politis, Paola Piccini
Chapter 11. Imaging non-motor aspects of Parkinson's disease / David J. Brooks, Nicola Pavese
Section III. Frontiers in PD treatment
Chapter 12. Gene therapy for dopamine replacement / Tomas Björklund, Erik Ahlm Cederfjäll, Deniz Kirik
Chapter 13. Neurotrophic factor therapy for Parkinson's disease / Suresh Babu Rangasamy, Katherine Soderstrom, Roy A.E. Bakay, Jeffrey H. Kordower
Chapter 14. Neural grafting in Parkinson's disease: Problems and possibilities / Patrik Brundin, Roger A. Barker, Malin Parmar
CHAPTER 15. Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia / Emma L. Lane, Anders Björklund, Stephen B. Dunnett, Christian Winkler
Chapter 16. Deep brain stimulation: state of the art and novel stimulation targets / Francisco A. Ponce, Andres M. Lozano
Chapter 17. The challenge of non-motor symptoms in Parkinson's disease / K. Ray Chaudhuri, Per Odin.