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LPCH Antibiogram: Gram Positive Cocci 2008

Values expressed are % susceptible by Broth Microdilution, Etest, or Disk Diffusion

    Beta-Lactams Others
  Number of Isolates Oxa-
cillin/ Naf- cillin
Penicillin or Ampicillin 1st Gener-
ation cephems
Cefur-
oxime
Ceftri-
axone
Mero-
penem
Genta-
micin
Cipro-
floxacin
Clinda-
mycin (a)
Erythro-
mycin
Nitro-
furantoin - urine
Co-trimox-
azole
Vanco-
mycin
Tetra-
cycline
Line-
zolid
      %S %I %R                          
Cost   $ $   $$ $$$ $$$ $ $$$ $ $ $ $ $ $ $$$
Staphylococcus aureus 430 80% 18% - - 80% - - - 96% - 80% 47% - 100% 100% - -
MRSA only 93 0% 0% - - 0% - - - 97% - 59% 8% - 100% 100% 96% -
Staphylococcus epidermidis 10 10% 10% - - 10% - - - 50% - 56% 22% - 90% 100% - -
Staphylococcus sp., Coagulase-negative 169 32% 11% - - 32% - - - 55% - 51% 24% - 68% 100% - -
Enterococcus faecium 18 - 28% 0% 72% - - - - - - - - - - 44% - 100%
Enterococcus faecalis 53 - 100% 0% 0% - - - - - - - - - - 98% - -
Enterococcus sp. (not identified to species) 183 - 92% 0% 8% - - - - - 85% - - 94% - 96% - -
Streptococcus group B (vag/anal screen) 246 - 100% 0% 0% - - - - - - 81% 78% - - - - -
viridans group streptococci 38 - 79% 18% 3% - - 92% - - - 83% 44% - - 100% - -
Streptococcus pneumoniae 43 - 58% (b) - 42% - 72% 93% (c) 88% - - 88% 70% - 74% 100% - -

Drug cost:
Low ($); Moderate ($$); High ($$$)

(a) Testing for inducible clindamycin resistance performed on S. aureus isolates, or by MD request.

(b) Based on meningitis interpretive criteria (more conservative). Nonmeningitis interpretation is 93%.

(c) Ceftriaxone uses the meningitis interpretive criteria (more conservative).

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