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Ask UsSHC Antibiogram: Streptococci & Enterococci
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SHC Antibiogram 2007
(printable PDF)
Percent Susceptible by Broth Microdilution, Etest, or Disk Diffusion
| No. Tested | Penicillin or Ampicillin | Cefuro- xime |
Ceftria- xone |
Vanco- mycin |
Erythro- mycin |
Clinda- mycin |
Mero- penem |
Trimetho- prim/ sulfa |
Tetra- cycline (Doxy- cycline) |
Genta- micin Synergy with Pen/Amp |
Strep- tomycin Synergy with Pen/Amp |
Moxi- floxacin |
Nitro- furan- toin (UTI only) |
Quino- pristin/ dalfo- pristin |
Cipro- floxacin |
Line- zolid |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| %S | %I | %R | |||||||||||||||||
| Streptococci | |||||||||||||||||||
| Grp. B (Strep. agalactiae) (a) | 327 | 100% | 0% | 0% | - | 100% | - | 69% | 72% | - | - | - | - | - | - | - | - | - | - |
| Viridans (various species) (b) | 136 | 82% | 16% | 2% | - | 96% | 100% | 59% | 81% | - | - | - | - | - | - | - | - | - | - |
| Strep. pneumoniae (c) | 74 | 78% d | - | 22% | 97% | 99% | 100% | 84% | 89% | 99% | 82% | - | - | - | 99% | - | - | - | - |
| Enterococci | |||||||||||||||||||
| Enterococcus (no species I.D.) (e,f) | 578 | 86% | 0% | 14% | - | - | 90% | - | - | - | - | 24% | - | - | - | 87% | - | 67% | 100% |
| Enterococcus faecalis (e) | 76 | 99% | 0% | 1% | - | - | 97% | - | - | - | - | - | 64% | 75% | - | 100% | - | 33% | 100% |
| Enterococcus faecium (e) | 80 | 9% | 0% | 91% | - | - | 43% | - | - | - | - | 40% | 79% | 40% | - | 0% | 90% | 0% | 99% |
| Cost ($) | $ | $ | $ | $ | $$ | $ | $ | $$ | $$ | $ | $ | $ | $ | $$ | $ | $$$ | $$ | $$$ | |
(a) Penicillin is the drug of choice for all beta hemolytic streptococci; penicillin resistance has not been documented.
(b) Clinically important species tested; MICs for penicillin and ceftriaxone performed on 129 strains.
(c) Penicillin-susceptible isolates are also susceptible to all other b-lactam agents. b-lactamase inhibitor combination drugs do not
add additional efficacy to penicillin alone.
(d) Based on meningitis interpretive criteria (more conservative). Nonmeningitis interpretation is 100%. Infectious diseases
consultation is recommended for meningitis in penicillin-allergic patients or those with resistant ceftriaxone or cefotaxime results.
(e) If susceptible, ampicillin is the drug of choice when
enterococci must be treated. Ampicillin susceptibility
predicts piperacillin susceptibility. Nitrofurantoin or ampicillin
is recommended for uncomplicated UTI. Serious infections
(septicemia, endocarditis) require both a b-lactam agent
and an aminoglycoside. Use vancomycin+aminoglycoside
only if strain is ampicillin-resistant or patient is penicillin
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allergic. High level resistance to gentamicin also indicates
lack of synergy for tobramycin, amikacin and kanamycin.
(f) Daptomycin not recommended for Enterococcus spp.