SHC Antibiogram: Staphylococci 2008

• SHC Antibiogram 2008   (printable PDF)

Percent Susceptible by Broth Microdilution

	No. Tested	Peni- cillin (a)	Naf- cillin, Oxa- cillin (b, c)	1st Gener- ation Cephems (c)	Vanco- mycin	Erythro- mycin	Clinda- mycin (d)	Genta- micin	Trimeth/ Sulfa	Moxi- floxacin	Tetra- cycline (Doxy)	Line- zolid
Staphylococcus aureus, ALL (b)	959	17%	69%	69%	100%	54%	82%	98%	99%	55%	94%	100%
MRSA (ONLY) (c)	295	0%	0%	0%	100%	6%	52%	98%	98%	10%	92%	100%
Staph. epidermidis	57	4%	27%	27%	98%	37%	60%	77%	63%	-	-	-
Staph. lugdunensis	38	68%	97%	97%	100%	84%	95%	100%	97%	-	-	100%
Staph. coagulase negative (other)	239	14%	40%	40%	100%	36%	65%	73%	68%	35%	-	100%
Cost ($)		$	$	$	$	$	$$	$	$	$$	$	$$$

(a) Penicillin-resistant staphylococci should be considered resistant to all penicillinase-sensitive penicillins, including ampicillin, amoxicillin, mezlocillin, piperacillin and ticarcillin.

(b) For empiric therapy where S. aureus is a potential pathogen, nafcillin and first generation cephalosporins are recommended drugs of choice for infections other than serious or systemic, for which vancomycin should be used until the susceptibility results are available. Vancomycin MIC 2mcg/ml, currenlty interpreted sensitive, is associated with increased treatment failure.

(c) Oxacillin resistant staphylococci (MRSA & MRSE) should be considered resistant to all penicillins, cephalosporins, imipenem and beta-lactams including combinations with clavulanic acid, sulbactam and tazobactam. Oxacillin susceptibility predicts susceptibility to all other beta-lactams.

(d) Clindamycin induction test not performed on all staphylococcal isolates.