Percent Susceptible by Broth Microdilution
| No. Tested | Peni- cillin (a) |
Naf- cillin, Oxa- cillin (b, c) |
1st Gener- ation Cephems (c) |
Vanco- mycin |
Erythro- mycin |
Clinda- mycin (d) |
Genta- micin |
Trimeth/ Sulfa | Moxi- floxacin |
Tetra- cycline (Doxy) |
Line- zolid |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Staphylococcus aureus, ALL(b) | 1003 | 12% | 64% | 64% | 100% | 50% | 79% | 97% | 99% | 64% | 95% | 100% |
| MRSA (ONLY) (c) | 349 | 0% | 0% | 0% | 100% | 5% | 49% | 96% | 100% | 21% | 96% | 100% |
| Staph. epidermidis | 25 | 12% | 32% | 32% | 100% | 41% | 55% | 56% | 36% | - | - | - |
| Staph. lugdunensis | 19 | 84% | 95% | 95% | 100% | 100% | 100% | 100% | 100% | - | - | 100% |
| Staph. coagulase negative (other) | 226 | 12% | 30% | 30% | 100% | 37% | 62% | 69% | 61% | 40% | - | 100% |
| Cost ($) | $ | $ | $ | $ | $ | $$ | $ | $ | $$ | $ | $$$ |
(a) Penicillin-resistant staphylococci should be considered resistant to all penicillinase- sensitive penicillins,
including ampicillin, amoxicillin, mezlocillin, piperacillin and ticarcillin.
(b) For empiric therapy where S. aureus is a potential pathogen, nafcillin and first generation cephalosporins are
recommended drugs of choice for infections other than serious or systemic, for which vancomycin should be used until the
susceptibility results are available.
(c) Oxacillin resistant staphylococci (MRSA & MRSE) should be considered resistant to all penicillins, cephalosporins,
imipenem and beta-lactams including combinations with clavulanic acid, sulbactam and tazobactam. Oxacillin susceptibility
predicts susceptibility to all other beta-lactams.
(d) Clindamycin induction test not performed on all staphylococcal isolates.