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Where can I find comprehensive drug data?

The Problem

You are searching for drug data and have exhausted public sources such as PubMed and specialized ones such as Micromedex and others listed on the Lane Pharmacy Portal.

So, are these the only sources you should search? No! A vast amount of superior-quality data are provided by proprietary databases available at the Lane Library on a consultation basis. No exhaustive drug search is complete without consulting these databases.

Why use these databases?

These databases are essential for:
  • Getting the most comprehensive answers for a compound, whether for a drug, a drug-to-be compound not yet available on the market, or a failed drug.
  • Ensuring an exhaustive understanding of all known drug side effects.
  • Understanding all aspects of the development of a drug, including pre-clinical, synthesis and toxicological properties.
  • Accessing the chemical properties of drugs and other medicinal compounds.

The Solution

Database Content Of note Access
EMBASE Comprehensive database of pharmaceutical and biomedical literature containing bibliographic records with citations and abstracts beginning in 1974. More 40% of its records are not in PubMed. EMBASE is one of the best source of drug information, particularly for hidden side effects, since EMBASE indexes adverse reactions worldwide. Dialog system - consult a Lane Liaison Librarian to have your search run.
SEDBASE, side effects of drugs Provides critical analyses of the published drug side effect literature on drugs currently in use. Focusses on drug side effects. Dialog system - consult a Lane Liaison Librarian to have your search run.
Derwent drug file Abstracts on all aspects of drug development, from chemistry and synthesis, through pharmacology and toxicology to clinical application, derived from journal and conference proceedings. Chemical structure images are provided for over 36,500 records. More research- than clinically-oriented Dialog system - consult a Lane Liaison Librarian to have your search run.
MDL Screening Compounds Directory Repository of all drug structures, as well as diverse, drug-like candidates and commpounds structurally related to drugs. Useful for high-throughput screening and compound structure studies; more research- than clinically-oriented; Available via DiscoveryGate (SUNet ID required) and consultation with a Swain Librarian.

Unique characteristics

  • Most of the databases listed above available via Dialog and require expert searching on a fee-for-service basis. See a Lane Liaison Librarian for details.

Additional sources

Source

Lane Librarian

ypouliot, September 18, 2009

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