What is ExPASy?
What is it?
The
ExPASy database provides integrated access to a variety of databases and molecular biology analytical tools dedicated to understanding proteins.
What is it for?
- Tasks relevant to proteomics (e.g., obtaining protein physical properties)
- Performing similarity searches, pattern searches and profile searches
- Identifying predicted post-translational modifications
- Performing topology prediction, including primary, secondary and tertiary structure analysis
What is in it?
- SWISS-PROT knowledgebase: a curated protein sequence database that provides high quality annotations (such as the description of the function of a protein, its domain structure, post-translational modifications and variants), a minimal level of redundancy and a high level of integration with other databases
- TrEMBL: contains computer-annotated entries for all sequences not yet integrated in SWISS-PROT. SWISS-PROT and TrEMBL are maintained collaboratively by the SIB and the European Bioinformatics Institute (EBI)
- SWISS-2DPAGE: a database of proteins identified on two-dimensional polyacrylamide gel electrophoresis (2D PAGE). SWISS-2DPAGE contains data from a variety of human and mouse biological samples as well as fromArabidopsis thaliana, Escherichia coli, Saccharomyces cerevisiae and Dictyostelium discoideum
- PROSITE: a database of protein domains and families. PROSITE contains biologically significant sites, patterns and profiles that help to reliably identify to which known protein family a new sequence belongs
- ENZYME: a repository of information relative to the nomenclature of enzymes
- SWISS-MODEL Repository: a database of automatically generated structural protein models
Key references
Source
Lane Librarian
Record created 6/1/2006.
ypouliot, September 16, 2009