Classes
Applications of Pathway Analysis using MetaCore
MetaCore is GeneGo’s unique bioinformatics technology for systems biology and pathway
analysis enables complete reconstruction of mammalian cellular functionality from
human, mouse, and rat-specific interactions data at the level of ligand-receptor interactions,
cell signaling and regulation and core metabolism. Whether you are working with one
gene or an extensive list from high throughput data, you can extract the associated
cellular functionality, compare several data sets to determine what biology is shared
or unique to each, and overlay and visualize expression data to help you formulate
and test hypotheses.
For researchers with Rodent data: The mouse and rat content in MetaCore (MetaRodent)
does not derive from orthologous gene matching between rodent and human, but rather
on the specific manual curation of rodent genes, proteins, protein complexes, protein
function, transcriptional regulation, etc. from experimental literature. MetaRodent
enables direct comparison between metabolism, signaling, and cellular processes in
human and model organisms, taking full account of the differences between human and
rodent biology. This is a critical feature, allowing the evaluation of multiple types
of systems biology data from experiments in model species, while facilitating the
appropriate interpretation of the outcome with respect to the potential effects in
man.
Hands-on Training: You are encouraged to bring your own data for analysis for the hands-on training session.
Attendees are welcome to participate in one-on-one instruction after the session.