Books by Subject
- Advances in HIV-1 assembly and release 2013SpringerOver the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle. This has been made possible by major advances in cell biology, virology, and structural biology. The field continues to move forward rapidly, with important new discoveries being reported on a regular basis. The impact of this progress across a broad spectrum of biomedical research has been substantial. The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research. The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.
- antimicrobe.orgLimited to 6 simultaneous usersIncludes information on antimicrobial therapy and alternative therapy when the drug of choice cannot be given. The resource delivers information via review articles, capsule summaries, mini-reviews, and a guided PubMed search to pick up post-publication research.
- Antiviral methods and protocols. Second edition. [2nd ed.] 2013Springer ProtocolsPart I Human immunodeficiency virus type 1 (HIV-1) -- Fluorescence-based high-throughput screening assay to identify HIV-1 inhibitors / Peggy Geluykens ... [et al.] -- Homogeneous time-resolved fluorescence assay to identify inhibitors of HIV-1 fusion / Liesbet Smeulders ... [et al.] -- Identification of HIV-1 reverse transcriptase inhibitors using a scintillation proximity assay / Bertrand Van Schoubroeck ... [et al.] -- Biochemical screening assays to identify HIV-1 integrase inhibitors / Marleen Clynhens ... [et al.] -- HIV-1 genotyping of the protease-reverse transcriptase and integrase genes to detect mutations that confer antiretroviral resistance / Peter Van den Eede ... [et al.] -- Part II Hepatitis viruses -- In vitro kinetic profiling of hepatitis C virus NS3 protease inhibitors by progress curve analysis / Rumin Zhang and William T. Windsor -- Novel hepatitis C virus NS5B polymerase assay of de novo initiated RNA synthesis directed from a heteropolymeric RNA template / Eric Ferrari and Hsueh-Cheng Huang -- Selecting and characterizing drug-resistant hepatitis C virus replicon / Inge Vliegen, Leen Delang, and Johan Neyts -- Cellular replicon-based phenotyping assay to determine susceptibility of hepatitis C virus clinical isolates to NS3/4A protease inhibitors / Leen Vijgen ... [et al.] -- Expression and purification of hepatitis C virus protease from clinical samples / Liesbet van der Helm -- Surface plasmon resonance as a tool to select potent drug candidates for hepatitis C virus NS5B polymerase / Erna Cleiren, Benoit Devogelaere, and Katleen Fierens -- Amplification and sequencing of the hepatitis C virus NS3/4A protease and the NS5B polymerase regions for genotypic resistance detection of clinical isolates of subtypes 1a and 1b / Diana Koletzki ... [et al.] -- Southern blot assay for detection of hepatitis B virus covalently closed circular DNA from cell cultures / Dawei Cai ... [et al.] -- In vitro phenotyping of recombinant hepatitis B virus containing the polymerase/reverse transcriptase gene from clinical isolates / Yang Liu and Kathryn M. Kitrinos -- Part III Flaviviruses -- Cell-based antiviral assays for screening and profiling inhibitors against dengue virus / Edwin Yunhao Gong ... [et al.] -- Duplex real-time RT-PCR assay for profiling inhibitors of four dengue serotypes / Edwin Yunhao Gong ... [et al.] -- High-throughput screening using dengue virus reporter genomes / Wolfgang Fischl and Ralf Bartenschlager -- Fluorimetric and HPLC-based dengue virus protease assays using a FRET substrate / Christoph Nitsche and Christian D. Klein -- Expression and purification of dengue virus NS5 polymerase and development of a high-throughput enzymatic assay for screening inhibitors of dengue polymerase / Edwin Yunhao Gong ... [et al.] -- Detection and quantification of flavivirus NS5 methyl- transferase activities / Siew Pheng Lim, Christophe Bodenreider, and Pei-Yong Shi -- Testing antiviral compounds in a dengue mouse model / Wouter Schul, Andy Yip, and Pei-Yong Shi -- Construction of self-replicating subgenomic west nile virus replicons for screening antiviral compounds / Sofia L. Alcaraz-Estrada, Erin Donohue Reichert, and Radhakrishnan Padmanabhan -- Part IV Herpes viruses -- Methods for screening and profiling inhibitors of herpes simplex viruses / Edwin Yunhao Gong -- In vivo evaluation of antiviral efficacy against genital herpes using mouse and guinea pig models / Frances Valencia, Ronald L. Veselenak, and Nigel Bourne -- Fluorescence-based high-throughput screening assay for identifying human cytomegalovirus inhibitors / Christel Van den Eynde ... [et al.] -- Part V Respiratory viruses -- Fluorescence-based high-throughput antiviral compound screening assay against respiratory syncytial virus / Leen Kwanten, Ben De Clerck, and Dirk Roymans -- Screening and evaluation of anti-respiratory syncytial virus compounds in cultured cells / Anna Lundin, Tomas Bergström, and Edward Trybala -- Evaluation of antiviral efficacy against human respiratory syncytial virus using cotton rat and mouse models / Joke Van den Berg, Leen Kwanten, and Dirk Roymans -- In vivo evaluation of antiviral compounds on respiratory syncytial virus using a juvenile vervet monkey (Chlorocebus pygerythrus) infection model / Lieselot Houspie ... [et al.] -- Methods to determine mechanism of action of anti-influenza inhibitors / Angela Luttick, Stephanie Hamilton, and Simon P. Tucker -- Methods for evaluation of antiviral efficacy against influenza virus infections in animal models / Donald F. Smee and Dale L. Barnard -- Part VI Alphaviruses -- Development of a high-throughput antiviral assay for screening inhibitors of chikungunya virus and generation of drug-resistant mutations in cultured cell / Edwin Yunhao Gong ... [et al.] -- Mouse model of chikungunya virus with utility in antiviral studies / Ashley Dagley and Justin G. Julander.
- Antiviral RNAi concepts, methods, and applications 2011Springer Protocols[Publisher-supplied data] Viruses and RNAi share an intricate relationship at many levels. RNAi is an important antiviral defense mechanism in plants and invertebrates, microRNAs of viral or cellular origin affect many aspects of virus biology, and replication of many, if not all, mammalian viruses can be suppressed by RNAi. Antiviral RNAi: Concepts, Methods, and Applications provides a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for the development and optimization of RNAi-based antiviral drugs. As RNAi is a central regulatory mechanism in the cell, the methods in this volume can also be applied out of the context of a virus infection. Divided into five convenient parts, this detailed volume reviews important basic concepts in the field of antiviral RNAi, provides experimental and bio-informatic tools for the analysis of small silencing RNAs, covers methods to biochemically dissect RNAi-based antiviral defense and viral counter-defense mechanisms, describes methods for the design, expression, and delivery of therapeutic antiviral siRNAs, and finally presents genome-wide RNAi approaches for the identification of factors involved in virus replication. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Antiviral RNAi: Concepts, Methods, and Applications serves as an ideal guide for both novice and experienced researchers alike striving to dissect the role of RNAi in the viral life cycle or to further boost the development of novel therapeutics and experimental tools based on RNAi technology.
- Since their initial discovery in the 1970's, astroviruses have been recognized as a leading cause of enteritis in infants, the elderly, and immunocompromised people, and were known to be widespread in animals and birds. In recent years, and with the advent of pyrosequencing, there has been a virtual explosion in the number of newly identified astrovirus genotypes. With this has come an increased understanding in astrovirus biology, structure, epidemiology, immunology, and disease pathogenesis including the likelihood of extraintestinal and systemic infections. The advent of new diagnostic tests that detect all of the currently identify human astrovirus strains may prove that these viruses are more prevalent in populations than currently realized.This book will provide state-of-the-art information on our current understanding of astroviruses for researchers, medical and veterinary providers, and diagnosticians as prepared by the leaders in the respective fields. The goal is to bring the reader up to date on the state of knowledge on this constantly evolving and exciting field of virology.
- Avian influenza 2008KargerEpidemiology of avian influenza / Osterhaus, A.D.M.E., Munster, V.J., Fouchier, R.A.M. -- H5N1 in Asia / Yen, H.-L. ... [et al.] -- Epidemiology and control of H5N1 avian influenza in China / Chen, H., Bu, Z., Wang, J. -- Avian influenza in Northern Eurasia / Lvov, D.K., Kaverin, N.V. -- Avian influenza in Italy, 1997-2006 / Capua, I. ... [et al.] -- Avian influenza outbreaks in Germany : development of new avian vaccines / Werner, O. ... [et al.] -- The role of pigs in interspecies transmission / Brown, I.H. -- History of research on avian influenza / Scholtissek, C. -- Reverse genetics of influenza viruses : applications in research and vaccine design / Neumann, G., Horimoto, T., Kawaoka, Y. -- Receptor specificity of influenza viruses and its alteration during interspecies transmission / Matrosovich, M.N., Gambaryan, A.S., Klenk, H.-K. -- Cleavage activation of the influenza virus hemagglutinin and its role in pathogenesis / Garten, W., Klenk, H.-D. -- Structure and function of the influenza A virus ribonucleoprotein : transcription and replication / Ortín, J. -- Influenza A virus polymerase : a determinant of host range and pathogenicity / Stech, J. -- Influenza A virus virulence and innate immunity : recent insights from new mouse models / Haller, O., Kochs, G., Staeheli, P. -- Signaling to life and death : influenza viruses and intracellular signal transduction cascades / Ludwig, S. ... [et al.] -- Cytokines in the pathogenesis of highly virulent influenza viruses in humans / Van Reeth, K. -- Antivirals and resistance / Hay, A.J., Collins, P.J., Russell, R.J. -- The 1918 influenza pandemic : lessons from the past raise questions for the future / Steel, J., Palese, P.
- Avian influenza virus 2008Springer ProtocolsA brief introduction to the avian influenza virus / Erica Spackman -- Avian influenza virus sample types, collection, and handling / Mary Lea Killian -- Avian influenza virus RNA extraction from tissue and swab material / Erica Spackman and David L. Suarez -- Type A influenza virus detection and quantitation by real-time RT-PCR / Erica Spackman and David L. Suarez -- Detection and identification of the H5 hemagglutinin subtype by real-time RT-PCR -- Avian influenza virus isolation and propagation in chicken eggs / Peter R. Woolcock -- Hemagglutination-inhibition test for avian influenza virus subtype identification and the detection and quantitation of serum antibodies to the avian influenza virus / Janice C. Pedersen -- Neuraminidase-inhibition assay for the identification of influenza A virus neuraminidase subtype or neuraminidase antibody specificity / Janice C. Pedersen -- Immunohistochemical staining for the detection of the avian influenza virus in tissues / Mary J. Pantin-Jackwood -- Wild bird surveillance for the avian influenza virus / Justin D. Brown and David E. Stallknecht -- Reverse genetics of the avian influenza virus / Chang-Won Lee and David L. Suarez -- Evaluating the cell-mediated immune response of avian species to avian influenza viruses / Darrell R. Kapczynski -- Measurement of avian cytokines with real-time RT-PCR following infection with the avian influenza virus / Darrell R. Kapczynski and Michael H. Kogut.
- Bacteriophages biology and applications 2005CRCnetBASE
- Baculovirus and insect cell expression protocols. 2nd ed. 2007Springer Protocols
- Cancer associated viruses 2012SpringerPeyton Rous: A Centennial Tribute to the Founding Father of Cancer Virology -- Viruses and Cancer: A Historical Perspective - HBV and Prevention of a Cancer -- Virus-Mediated Cell Proliferation -- Viral-Encoded Genes and Cancer -- Oncogenic Viruses and Cancer Transmission -- DNA Viruses and Cancer: Taking a Broader Look -- Herpesviruses and Cancer -- Lymphocryptoviruses: EBV and Its Role in Human Cancer -- Nonhuman Primate Gamma-herpesviruses and Their Role in Cancer -- Rhadinoviruses: KSHV and Associated Malignancies -- Retroperitoneal Fibromatosis Herpesvirus and Kaposi's Sarcoma-Like Tumors in Macaques -- Murine Gammaherpesvirus-Associated Tumorigenesis -- Marek's Disease Virus-Induced T-Cell Lymphomas -- Polyomaviruses and Cancer -- Polyomavirus SV40: Model Infectious Agent of Cancer -- BK Polyomavirus and Transformation -- Polyomavirus JC and Human Cancer: Possible Role of Stem Cells in Pathogenesis -- Merkel Cell Polyomavirus -- Human Papillomaviruses and Cancer -- Tumorigenesis by Adenovirus Type 12 E1A -- Overview of Hepatitis Viruses and Cancer -- Hepadnaviruses and Hepatocellular Carcinoma -- Hepatitis C Virus and Hepatocellular Carcinoma -- Human and Animal Retroviruses: HIV-1 Infection Is a Risk Factor for Malignancy -- HTLV-1 and Oncogenesis -- Human T-Cell Leukemia Virus Type 2 (HTLV-2) Biology and Pathogenesis -- Mechanisms of Oncogenesis by Avian and Murine Retroviruses -- Rous Sarcoma Virus: Contributions of a Chicken Virus to Tumor Biology, Human Cancer Therapeutics, and Retrovirology -- Mouse Mammary Tumor Virus and Cancer -- Jaagsiekte Sheep Retrovirus and Lung Cancer -- Small RNAs and Their Role in Herpesvirus-Mediated Cancers -- Viral Malignancies in HIV-Associated Immune Deficiency.
- Cancer causing viruses and their inhibitors 2014CRCnetBASE"Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), Human papilloma virus (HPV), Human herpes virus 8 (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV), Human immunodeficiency virus (HIV/AIDS), Oncolytic viruses. This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies"--Provided by publisher.
- Cell entry by non-enveloped viruses 2010SpringerPreface / John E. Johnson, Peter K. Vogt -- Flock House Virus: A model system for understanding non-enveloped virus entry and membrane penetration / Amy Odegard, Manidipa Banerjee and John. E. Johnson -- The calciviruses / Umesh Katpally and Thomas J. Smith -- Picornaviruses / Tobias J. Tuthill ... [et al.] -- From touchdown to transcription: The reovirus cell entry pathway / Pranav Danthi ... [et al.] -- Rotavirus cell entry / Matthew Baker and B.V. Venkataram Prasad -- Structures and functions of parvovirus capsids and the process of cell infection / Colin R. Parrish -- Cellular entry of polyomaviruses / Billy Tsai and Mengding Qian -- Adenovirus / Jason G. Smith ... [et al.].
- Challenge of highly pathogenic microorganisms mechanisms of virulence and novel medical countermeasures 2010SpringerThe Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics / Arthur M. Friedlander -- Proteomic Studies of Bacillus anthracis Reveal In Vitro CO2-Modulation and Expression During Infection of Extracellular Proteases / Theodor Chitlaru, Orit Gat, Galia Zaide, Haim Grosfeld and Izhak Inbar, et al. -- Dynamics of Bacillus anthracis Infection and Control Mechanisms / Pierre L. Goossens, Ian J. Glomski, Lhousseine Touqui and Michèle Mock -- Survival and Trafficking of Yersinia pestis in Non-acidified Phagosomes in Murine Macrophages / James B. Bliska -- The Inverse Relationship Between Cytotoxicity of Y. pestis and Its Virulence / Emanuelle Mamroud, Avital Tidhar, Yinon Levy, Erez Bar-Haim and Gideon Halperin, et al. -- The NlpD Lipoprotein of Yersinia pestis is Essential for Cell Separation and Virulence / Avital Tidhar, Yehuda Flashner, Sara Cohen, Yinon Levy and Ayelet Zauberman, et al. -- Dissection of the Functions of the IglC Protein of Francisella tularensis / Jeanette E. Bröms, Moa Lavander and Anders Sjöstedt -- Yersinia pestis Lipopolysaccharide in Host-Pathogen Interactions / Andrey P. Anisimov, Svetlana V. Dentovskaya, Anna N. Kondakova, Buko Lindner and Rima Z. Shaikhutdinova, et al. -- The Interactions Between Pathogens and Dendritic Cells: From Paralysis of Cells to Their Recruitment for Bacterial Colonization / Baruch Velan, Erez Bar-Haim, Gal Markel, Hila Cohen and Ayelet Zauberman, et al. -- Comparative Approaches to Identify Host Factors Specifically Targeted by Yersinia pestis During the Infectious Process / Françoise Guinet, Patrick Avé, Louis Jones, Michel Huerre and Elisabeth Carniel -- Poxvirus Entry into Host Cells / Bernard Moss, Zain Bengali, Himani Bisht, Jason P. Laliberte and P.S. Satheskumar -- Role of A33R Amino-Acid 118L in the Interactions of Vaccinia Virus with the Host / Nir Paran, Shlomo Lustig, Anat Zvi, Tomer Israely and Sharon Melamed, et al. -- Inhibitors of Innate Immunity from Vaccinia Virus / Geoffrey L. Smith -- Brucella Species Synchronize Their Life Cycle to the Gestation Cycle of Their Ruminant Hosts / Svetlana Bardenstein and Menachem Banai -- MMP-9 as a Marker for Vaccinia Virus Related Encephalitis / Tomer Israely, Sharon Melamed, Noam Erez, Boaz Politi and Udy Olshevsky, et al. -- Epidemic Cowpox Virus Infections in Germany / Andreas Kurth and Andreas Nitsche -- The Two Partner Secretion Transporters of Yersinia pestis: Cloning, Immunogenicity and In Vivo Expression Following Airway Infection / Yinon Levy, Anat Zvi, Haim Grosfeld, Avital Tidhar and David Gur, et al. -- Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX) / Adi Beth-Din, Ofir Israeli, Ohad Shifman, Dana Stein and Einat Ben-Arie, et al. -- Subtyping Biothreat Bacterial Pathogens / Paul Keim and Talima Pearson -- A Rapid Method for Bacillus anthracis Genotyping / Haim Levy, Morly Fisher, Naomi Ariel, Shay Weiss and Anat Zvi, et al. -- Tularemia - A Disease with an Uncertain Impact on Public Health / Roland Grunow, Daniela Jacob, Andrea Kühn and Herbert Nattermann -- Consequences of Antibiotic Treatment of Francisella tularensis Airways Infections / Erez Bar-Haim, Hila Cohen, Raphael Ber, Ofer Cohen and Avigdor Shafferman -- Novel Live Vaccine Candidates Against Airborne Francisella tularensis / Wayne Conlan and Anders Sjöstedt -- Effect of Disruption of mglA on the Virulence and Immunogenicity of the Francisella tularensis Live Vaccine Strain (LVS) / Ofer Cohen, Galia Zaide, Erez Bar-Haim, Itai Mendelson and Orit Gat, et al. -- Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates / Anat Zvi, Naomi Ariel and Avigdor Shafferman -- Modified Vaccinia Virus Ankara (MVA) based Vaccines - Immunostimulatory and Protective Capacity / Michael H. Lehmann, Melanie Kremer, Yasemin Suezer and Gerd Sutter -- Therapeutic Potential of Vaccinia Hyper Immune Sera in Mouse Models of Lethal Orthopoxviruses Infection / Sharon Melamed, Nir Paran, Tomer Israely, Noam Erez and Shaul Reuveny, et al. -- A Live Plaque Vaccine Candidate with Improved Safety and Immunogenecity / V.A. Feodorova, L.N. Pan'kina, E.P. Savostina, O.S. Kuznetsov and N.P. Konnov, et al. -- Protection Against Plague Afforded by Treatment with Polyclonal αLcrV and αF1 Antibodies / Yinon Levy, Yehuda Flashner, Ayelet Zauberman, Avital Tidhar and Moshe Aftalion, et al. -- Combination of Anthrax-Toxin Neutralizing Antibodies: Analysis of Synergism/Antagonism Effect / Ohad Mazor, Einat Ben-Arie, Adva Mechaly, Ronit Rosenfeld and Hadar Marcus, et al. -- The Efficacy of Antibiotic Treatment to Cure Guinea Pigs Intranasally Infected with Bacillus anthracis Spores / Zeev Altboum, Haim Levy, Shay Weiss, Avi Pass and Nili Rothschild, et al. -- Reverse Vaccinology in Bacillus anthracis / Avigdor Shafferman, Orit Gat, Naomi Ariel, Theodor Chitlaru and Haim Grosfeld, et al.
- Part I. Virology, pathogenesis, and clinical and epidemiological features of disease -- Part II. Host response to infection and genetics of disease -- Part III. Vaccine platforms and treatment options -- Part IV. Animal and tissue culture models of infection -- Part V. Conclusions -- Index.
- Chemokines and viral infection 2006SpringerFunctional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system / T.E. Lane, J.L. Hardison, and K.B. Walsh -- Cytokine and chemokine networks : pathways to antiviral defense / T.P. Salazar-Mather and K.L. Hokeness -- Herpes simplex virus and the chemokines that mediate the inflammation / D.J.J. Carr and L. Tomanek -- Influence of proinflammatory cytokines and chemokines on the neuropathogenesis of oncornavirus and immunosuppressive lentivirus infections / K.E. Peterson and B. Chesebro -- HIV-1 coreceptors and their inhibitors / N. Ray and R.W. Doms -- A viral conspiracy : hijacking the chemokine system through virally encoded pirated chemokine receptors / H.F. Vischer, C. Vink, and M.J. Smit.
- Part I. Natural history of chronic HCV -- 1. Epidemiology of chronic HCV / Gary L. Davis -- 2. Acute HCV / Katja Deterding, Heiner Wedemeyer, and Michael P. Manns -- 3. Assessing the progression of chronic HCV to cirrhosis / Gonzolo Crespo, Stella M. Martinez, and Xavier Forns -- 4. Chronic HCV and steatosis / Dawn McDowell Torres and Stephen A. Harrison -- 5. Chronic HCV and hepatocellular carcinoma / Morris Sherman -- 6. Extrahepatic manifestations of chronic HCV / Vincenza Calvaruso and Antonio Craxì -- 7. Chronic HCV and HIV coinfection / Patrick Ingiliz, Maud Lemoine, and Yves Benhamou -- 8. Chronic HCV in patients with renal disease / Paul Martin and Fabrizio Fabrizi -- 9. Does treatment alter the natural history of chronic HCV? / Fasiha Kanwal and Bruce R. Bacon -- Part II. Treatment of chronic HCV with interferon-based therapy -- 10. Treatment with interferon and ribavirin / William Kemp and Stuart K. Roberts -- 11. Immune modulators and other agents / Edgar D. Charles and Ira M. Jacobson -- 12. Measuring HCV RNA and assessing virologic response / Jean-Michel Pawlotsky -- 13. Response-guided therapy / Mitchell L. Shiffman -- 14. Managing the side effects of therapy / Curtis Cooper -- 15. Genetics of virologic response / Alison B. Jazwinski and Andrew J. Muir -- 16. Maintenance therapy with peginterferon / Raza Malik and Nezam H. Afdhal -- Part III. Anti-viral therapy for chronic HCV -- 17. Antiviral targets in HCV / B. Kronenberger and S. Zeuzem -- 18. Mutations and the development of anti-viral resistance / Anna Maria Geretti and Geoff Dusheiko -- 19. Peginterferon, ribavirin and anti-viral triple therapy / Patrick Marcellin, Nathalie Boyer, and Tarik Asselah -- 20. Treating chronic HCV without interferon and/or ribavirin / Edward J. Gane -- 21. Maintenance therapy with oral antiviral agents / Andrew Aronsohn and Donald Jensen -- Part IV. Liver transplantation for chronic HCV -- 22. Natural history of chronic HCV after liver transplantation / Bart J. Veldt and Michael R. Charlton -- 23. Use of HCV-positive organs in patients with and without chronic HCV / Elizabeth C. Verna and Robert S. Brown Jr. -- 24. Treating HCV prior to liver transplantation / Alvaro Martinez-Camacho, Brett E. Fortune, and Gregory T. Everson -- 25. Treating HCV after liver transplantation / Michael Chang, Hubert Sung, and Sammy Saab.
- Comparative hepatitis 2008Springer
- Congenital and other related infectious diseases of the newborn. 1st ed. 2007ScienceDirect
- Considerations for viral disease eradication lessons learned and future strategies : workshop summary 2002NAP
- Coronavirus replication and reverse genetics 2005SpringerCoronavirus genome structure and replication / D.A. Brian and R.S. Baric -- Coronavirus transcription : a perspective / S.G. Sawicki and D.L. Sawicki -- The coronavirus replicase / J. Ziebuhr -- Viral and cellular proteins involved in coronavirus replication / S.T. Shi and M.M.C. Lai -- Coronavirus reverse genetics by targeted RNA recombination / P.S. Masters and P.J.M. Rottier -- Coronavirus reverse genetics and development of vectors for gene expression / L. Enjuanes ... [et al.] -- Reverse genetics of coronaviruses using vaccinia virus vectors / V. Thiel and S.G. Siddell -- Development of mouse hepatitis virus and SARS-CoV infectious cDNA constructs / R.S. Baric and A.C. Sims.
- Crimean-congo hemorrhagic fever a global perspective 2007Springer
- Subcutaneous and deep mycoses -- Hyalohyphomycosis -- Superficial mycoses -- Algae -- Mycobacteria -- Viruses -- Rickettsiae -- Crusted scabies -- Protozoa -- Helminth -- Spirochete -- Gram-Positive bacteria -- Gram-negative bacteria -- Viral related malignancies -- Clues to the diagnosis of skin lesions in the immunocompromised host -- Differential diagnoses.
- Cysteine proteases of pathogenic organisms 2011Springer"Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research"--Provided by publisher.
- Dengue virus 2010SpringerProspective cohort studies of dengue viral transmission and severity of disease / Timothy P. Endy, In-Kyu Yoon, Mammen P. Mammen -- Control of dengue virus translation and replication / Suman M. Paranjape, Eva Harris -- Subversion of interferon by dengue virus / Jorge L. Munoz-Jordan -- Dengue virus virulence and transmission determinants / R. Rico-Hesse -- Systemic vascular leakage associated with dengue infections - the clinical perspective / Dinh D. Trung, Bridget Wills -- Markers of dengue disease severity / Anon Srikiatkhachorn, Sharone Green -- Cellular immunology of sequential dengue virus infection and its role in disease pathogenesis / Alan L. Rothman -- HLA and other gene associations with dengue disease severity / H.A.F. Stephens -- Vector dynamics and transmission of dengue virus: implications for dengue surveillance and prevention strategies / Thomas W. Scott, Amy C. Morrison -- Dengue vaccine candidates in development / Anna P. Durbin, Stephen S. Whitehead -- Targeted mutagenesis as a rational approach to dengue virus vaccine development / Joseph E. Blaney Jr., Anna Pl Durbin, Brian R. Murphy, Stephen S. Whitehead.
- Diabetes and viruses 2013SpringerDiabetes, in all of its forms, now constitutes a growing health concern, affecting all segments of the world's population. There is great interest in the factors which influence its etiology and progression. Among these, a number of viruses feature prominently. Hindered by technological limitations, research into this relationship has hitherto been scarce. Recent advances, however, have opened up the field and there is a burgeoning body of literature on the subject. Unfortunately, this literature has been diffuse and often difficult to access.For the first time, this book compiles the views of many of the world's experts in the field. It addresses questions, ranging from how viruses may destroy or modify the function of pancreatic islets; to which viruses are the most likely culprits; to whether vaccines or etiologic therapies might be used to prevent virus-induced diabetes. Diabetes and Viruses is the first comprehensive volume on an important and expanding field of research that is of interest to clinicians, healthcare managers, epidemiologists, veterinarians, and basic scientists.
- DNA tumor viruses 2009SpringerPolyomavirus life cycle / Ellen Fanning, Xiaorong Zhao, and Xiaohua Jiang -- Transformation by polyomaviruses / Dweepanita Das and Michael J. Imperiale -- Polyomaviruses and disease / Jaime M. Kean and Robert L. Garcea -- The life cycle of human papillomaviruses / Cary A. Moody and Laimonis A. Laimins -- Papillomavirus transformation / Kimberly Johung and Daniel DiMaio -- Papillomaviruses : biology, diversity, and pathogenesis / Hans-Ulrich Bernard -- Adenovirus transformation / Patrick Hearing -- Overview of the large DNA tumor viruses / Subhash C. Verma ... [et al.] -- Epidemiology of EBV infection / Rosemary Rochford -- EBV diseases / Joseph S. Pagano -- The Epstein-Barr virus genome / Jeffery T. Sample ... [et al.] -- Epstein-Barr virus transforming proteins : biologic properties and contribution to oncogenesis / Nancy Raab-Traub -- The Epstein-Barr virus lytic life cycle / Sankar Swaminathan and Shannon Kenney -- Epstein-Barr virus latent infection nuclear proteins : genome maintenance and regulation of lymphocyte cell growth and survival / Eric Johannsen ... [et al.] -- Epstein-Barr virus entry / Richard Longnecker, Lindsey Hutt-Fletcher, and Theodore Jardetzky -- EBV immunotherapy / Leslie E. Huye and Cliona M. Rooney -- KSHV epidemiology and subtype evolution / Gary S. Hayward and Denise Whitby -- Introduction to diseases associated with Kaposi's sarcoma-associated herpesvirus / Patrick S. Moore and Yuan Chang -- Organization and expression of the Kaposi's sarcoma-associated herpesvirus genome / Yan Yuan and Rolf Renne -- KSHV latent genes and their regulation / Dirk P. Dittmer -- Regulation of expression, mode of action and downstream targets of ORF50 protein in KSHV lytic cycle activation / Pey-Jium Chang, Jianjiang Ye, and George Miller -- HHV-8/KSHV proteins involved in signaling and transformation / Silke Hartmann, Thomas F. Schulz, and John Nicholas -- KSHV entry and infection of target cells / Bala Chandran and Neelam Sharma-Walia -- KSHV immune evasion / Chengyu Liang ... [et al.] -- Non-coding regulatory RNAs of the DNA tumor viruses / Christopher S. Sullivan and Bryan R. Cullen -- AIDS and associated malignancies / William J. Harrington, Charles Wood, and C. Wood -- Primate models for gammaherpesvirus-associated malignancies / Ilhem Messaoudi, Blossom Damania, and Scott W. Wong -- Murine gammaherpesvirus 68 infection of mice : a small animal model for characterizing basic aspects of gammaherpesvirus pathogenesis / James Craig Forrest, Laurie T. Krug, and Samuel H. Speck.
- EBNA1 and Epstein-Barr virus associated tumours 2013SpringerIntroduction -- Roles of EBNA1 at EBV Episomes -- EBNA1-DNA Interactions -- EBNA1 Contributions to EBV-Associated Tumours -- Cellular Effects of EBNA1 -- Conclusion.
- The Overview of Needs and Requirements covers the costs of the Ebola response and preparedness activities. The needs and requirements are based on the latest information available from each of the most affected countries. The national plans and budgets comprise the framework and the Overview of Needs and Requirements defines the contributions planed by the UN system as well as the major international civil society organizations.
- A global perspective on the management and prevention of emerging and re-emerging diseases Emerging infectious diseases are newly identified or otherwise previously unknown infections that cause public health challenges. Re-emerging infectious diseases are due to both the reappearance of and an increase in the number of infections from a disease that is known, but which had formerly caused so few infections that it was no longer considered a public health problem. The factors that cause the emergence or re-emergence of a disease are diverse. This book takes a look at the worl
- Emerging viruses in human populations. 1st ed. 2007ScienceDirect
- v. 2 Springer
- Fields Virology. 5th ed. 2007Ovid
- Fields Virology. 6th ed. 2013OvidVirology: from contagium fluidum to virome -- Principles of virology -- Principles of virus structure -- Virus entry and uncoating -- Viral replication strategies -- Virus assembly -- Viruses, cell transformation, and cancer -- Innate responses to viral infections -- Adaptive immune response to viral infections -- Pathogenesis of viral infection -- Virus evolution -- Epidemiology -- Antiviral agents -- Immunization against viral diseases -- Diagnostic virology -- Picornaviridae: the viruses and their replication -- Enteroviruses: polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses -- Rhinoviruses -- Hepatitis A virus -- Caliciviridae: the noroviruses -- Astroviruses -- Togaviridae -- Alphaviruses -- Rubella virus -- Flaviviridae -- Flaviviruses -- Hepatitis C virus -- Coronaviridae -- Arteriviruses -- Mononegavirales -- Rhabdoviridae -- Filoviridae: marbug and ebola viruses -- Paramyxoviridae -- Parainfluenza viruses -- Mumps virus -- Measles virus -- Henipaviruses -- Respiratory syncytial virus and metapneumovirus -- Bornaviridae -- Orthomyxoviridae -- Orthomyxoviruses -- Bunyaviridae -- Arenaviridae -- Orthoreoviruses -- Rotaviruses -- Orbiviruses -- Retroviridae -- Human t-cell leukemia virus types 1 and 2 -- Human immunodeficiency viruses: replication -- HIV-1: pathogenesis, clinical manifestations, and treatment -- Nonhuman lentiviruses -- Foamy viruses -- Polyomaviruses -- Papillomaviruses -- Adenoviridae -- Adenoviruses -- Parvoviridae -- Circoviridae -- Herpesviridae -- Herpes simplex viruses -- Epstein-Barr virus -- Cytomegaloviruses -- Varicella-Zoster virus -- Human herpesviruses 6 and 7 -- Kaposi's A. sarcoma-associated herpesvirus -- Poxiviridae -- Poxviruses -- Hepadnaviruses -- Hepatitis D (delta) virus -- Hepatitis E virus -- Mimivirus, other viruses infecting phagocytic protists, and their virophages -- Plants viruses -- Insect viruses -- Viruses and prions of yeasts, fungi, and unicellular eukaryotes -- Bacteriophages -- Prions.
- Filoviruses a compendium of 40 years of epidemiological, clinical, and laboratory studies 2008SpringerIntroduction -- History of filoviral diseases outbreaks -- Clinical presentation of filoviral disease -- Filoviral disease pathology -- Geographic distribution of filoviruses : serological surveys -- Ecology of filoviruses : search for reservoirs -- Cultivation of filoviruses -- Molecular characteristics of filoviruses -- Laboratory diagnosis of filoviral disease -- Outbreak containment -- Inactivation of filoviruses and disinfection protocols -- Vaccine development -- Treatment of filoviral disease
- Foot-and-mouth disease virus 2005Springer
- Forgotten cure the past and future of phage therapy 2012Springer1. Helpful Little Bodies -- 2. Inside Stalin's Empire -- 3. The Fading of Phage Therapy -- 4. Naked Genes -- 5. 'They're Not a Panacea:' Phage Therapy in the Soviet Union and Georgia -- 6. In Poland: Phages for Diabetes? -- 7. The Renaissance of Phage Therapy -- 8. The Startups -- 9. Four Companies, Four Strategies -- 10. Cows and Chickens -- 11. Approval, At Last -- 12. In Treatment.
- Function and control of the Spx-family of proteins within the bacterial stress response 2013SpringerThis SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence. The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.
- Glycovirology protocols 2007Springer ProtocolsThe use of monoclonal antibodies and lectins to identify changes in viral glycoproteins that are influenced by glycosylation : the case of respiratory syncytial virus attachment (G) glycoprotein / Joanna Rawling and José A. Melero -- Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS-CoV / Shuo Shen, Timothy H.P. Tan, and Yee-Joo Tan -- Analysis of glycoproteins of viruses in the family bunyaviridae / Xiaohong Shi and Richard M. Elliott -- Secretion of respiratory syncytial virus fusion protein from insect cells using the baculovirus expression system / Boon-Huan Tan, Gaie Brown, and Richard J. Sugrue -- Characterization of the dengue virus envelope glycoprotein expressed in Pichia pastoris / Boon-Huan Tan, Jian Lin Fu, and Richard J. Sugrue -- Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins / Alexander W. Tarr ... [et al.]. Viruses and glycosylation : an overview / Richard J. Sugrue -- Interaction between respiratory syncytial virus and glycosaminoglycans, including heparan sulfate / Louay K. Hallak, Steven A. Kwilas, and Mark E. Peeples -- Expression of the severe acute respiratory syndrome coronavirus 3a protein and the assembly of coronavirus-like particles in the baculovirus expression system / Sehaam Khan, Mah-Lee Ng, and Yee-Joo Tan -- The C type lectins DC-SIGN and L-SIGN : receptors for viral glycoproteins / Pierre-Yves Lozach ... [et al.] -- Functional analysis of the N-linked glycans within the fusion protein of respiratory syncytial virus / Ping Li ... [et al.] -- Expression and purification of viral glycoproteins using recombinant vaccinia viruses for functional and structural studies / Zhu-Nan Li and David A. Steinhauer -- The use of two-dimensional SDS-PAGE to analyze the glycan heterogeneity of the respiratory syncytial virus fusion protein / Terence P. McDonald and Richard J. Sugrue --
- Group B coxsackieviruses 2008SpringerCoxsackie B viruses: an introduction / B.W. Mahy -- Coxsackieviruses and quasispecies theory: evolution of enteroviruses / E. Domingo ... [et al.] -- Comparative genomics of the coxsackie B viruses and related enteroviruses / M.S. Oberste -- Group B coxsackievirus virulence / S. Tracy and C. Gauntt -- The coxsackievirus and adenovirus receptor / P. Freimuth, L. Philipson and S.D. Carson -- Coxsackievirus B RNA replication: lessons from poliovirus / P. Sean and B.L. Semler -- CVB translation: lessons from the polioviruses / J.M. Bonderoff and R.E. Lloyd -- Preferential coxsackievirus replication in proliferating/activated cells: implications for virus tropism, persistence, and pathogenesis / R. Feuer and J.L. Whitton -- The impact of CVB3 infection on host cell biology / D. Marchant ... [et al.] -- Host immune responses to coxsackievirus B3 / S. Huber -- Pediatric group B coxsackievirus infections / J.R. Romero -- CVB-induced pancreatitis and alterations in gene expression / A.I. Ramsingh -- The CVB and etiology of type 1 diabetes / K.M. Drescher and S.M. Tracy -- Persistent coxsackievirus infection: enterovirus persistence in chronic myocarditis and dilated cardiomyopathy / N.M. Chapman and K.S. Kim -- Autoimmunity in coxsackievirus infection / N.R. Rose -- CVB infection and mechanisms of viral cardiomyopathy / K.U. Knowlton.
- Introduction: Nipah Virus--Discovery and Origin / Kaw Bing Chua -- Ecological Aspects of Hendra Virus / Hume Field, Gary Crameri, Nina Yu-Hsin Kung and Lin-Fa Wang -- Epidemiology of Henipavirus Disease in Humans / Stephen P. Luby and Emily S. Gurley -- Molecular Virology of the Henipaviruses / Paul A. Rota and Michael K. Lo -- Henipavirus Receptor Usage and Tropism / Olivier Pernet, Yao E Wang and Benhur Lee -- Henipavirus Membrane Fusion and Viral Entry / Hector C. Aguilar and Ronald M. Iorio -- Clinical and Pathological Manifestations of Human Henipavirus Infection / K. T. Wong and C. T. Tan -- Henipaviruses in Their Natural Animal Hosts / D. J. Middleton and H. M. Weingartl -- Nipah and Hendra Virus Interactions with the Innate Immune System / Christopher F. Basler -- Animal Challenge Models of Henipavirus Infection and Pathogenesis / Thomas W. Geisbert, Heinz Feldmann and Christopher C. Broder -- Diagnosis of Henipavirus Infection: Current Capabilities and Future Directions / Lin-Fa Wang and Peter Daniels -- Immunization Strategies Against Henipaviruses / Christopher C. Broder, Thomas W. Geisbert, Kai Xu, Dimitar B. Nikolov and Lin-Fa Wang, et al.
- Innate immunity in type C hepatitis / Tetsuo Takehara and Norio Hayashi -- Mechanisms of interferon action and resistance in chronic hepatitis C virus infection: lessons learned from cell culture studies / Srikanta Dash ... [et al.] -- Immunological parameters influencing adaptive immune responses to the hepatitis C virus / Patrick Bertolino, Geoffrey W. McCaughan, and David G. Bowen -- Immune responses against the hepatitis C virus and the outcome of therapy / Paul Klenerman and Eleanor Barnes -- Other microbial components associated with hepatitis C virus infection: their effects on interferon- a/ribavirin treatment / Luigi Amati, Vittorio Pugliese, and Emilio Jirillo -- Interferon-induced effector proteins and hepatitis C virus replication / Michael Frese and Eva Dazert -- Treatment of chronic hepatitis C with different genotypes / James Fung, Ching-Lung Lai, and Man-Fung Yuen -- Interferon treatment of hepatitis C virus infection: from basic biology to clinical application / Norihiro Furusyo, Masayuki Murata, and Jun Hayashi -- Interferon-based therapy for hepatitis C virus infections / Ming-Lung Yu and Wan-Long Chuang -- Treatment of chronic hepatitis C in "difficult-to-treat" patients in the clinical setting / Ana Moreno, Rafael Bárcena, and Carmen Quereda -- Effects of combined IFN-alpha/ribavirin treatment in HCV disease-related progression / Davide Festi ... [et al.] -- Pegylated interferons: clinical applications in the management of hepatitis C infection / S. James Matthews and Christopher McCoy.
- Molecular biology of varicella-zoster virus / Rahaus, M., Desloges, N., Wolff, M.H -- Latency and reactivation of VZV / Lungu, O., Gershon, A.A. -- Laboratory confirmation of herpes zoster / Ludwig, B., Buxbaum, S., Doerr, H.W. -- Clinical picture and complications of herpes zoster: the view of the dermatologist / Gross, G. -- Ophthalmic manifestations of herpes zoster infection / Guembel, H. -- (Herpes) zoster oticus / Pau, H.W. -- Neuroanatomy of pain and neuropathology of herpes zoster and postherpetic neuralgia / Wree, A., Usunoff, K.G. -- Postherpetic neuralgia and other neurologic complications / Baron, R. -- Varicella-zoster virus infections during pregnancy / Sauerbrei, A., Wutzler, P. -- Herpes zoster in the immunocompromised host / Schöfer, H. -- Chickenpox and zoster in marrow transplant recipients / Genvresse, I., Maschmeyer, G. -- General aspects of therapy / Gross, G. -- Antiviral therapy of shingles in dermatology / Lilie, H.M., Wassilew, S.W. -- Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d] pyrimidine nucleoside analogues (BCNAS) / Clercq, E.D. -- Therapy of zoster pain, postherpetic neuralgia and other neurological complications / Baron, R. -- Epidemiology of herpes zoster: what has changed? / Allwinn, R., Buxbaum, S., Doerr, H.W. -- Live attenuated varicella vaccine / Gershon, A.A.
- HIV glycans in infection and immunity 2014SpringerGlycosylation is a common and extremely important modification in biological molecules, particularly of proteins. HIV Glycans in Infection and Immunity provides an overview of the roles of glycans in the transmission/infection, antigenicity, and immunogenicity of HIV and the HIV envelope glycoprotein. It explores recent advances in the understanding of the impact of HIV glycans in infection and their promise for immunological and therapeutic intervention. Novel collaborations between glycobiologists and immunologists in recent years have led to key advances in the understanding of HIV glycans. These cross-disciplinary endeavors, their achievements and their impact on the field are all addressed, herein.-- Source other than Library of Congress.
- HPV and cancer 2012Springer"HPV and Cancer" is a concise read that covers all aspects of the Human Papilloma Virus as it relates to human cancers. While written by professionals, it design to be understandable by those that are not in the field, yet it has the technical details that professionals want to stay abreast of this changing field. The book starts out the history of HPV and progresses into the molecular biology of the virus and our current understand of the structure and functions of the proteins and genes it encodes.
- HPV and head and neck cancers 2015SpringerAnatomical sites and subsites of head and neck cancer -- Epidemiology of oral HPV infection and HPV-associated head and neck cancer -- Frequent behavioural questions with an HPV-positive malignancy of the head and neck -- The molecular biology of HPV-related head and neck cancer -- The diagnosis of HPV-related head and neck squamous cell carcinoma: Recognition of its microscopic appearance and the use of ancillary detection assays -- Clinical management of HPV-related oropharyngeal cancer -- The role of vaccines for HPV-related head and neck cancers -- The care of the HPV-negative head and neck cancer patient: Presentation, prognosis, treatment. .
- Human antibody therapeutics for viral disease 2008SpringerTherapeutic control of hepatitis C virus: the role of neutralizing monoclonal antibodies / Z. Y. Keck ... [et al.] -- Antibodies for HIV treatment and prevention: window of opportunity? / M. Huber ... [et al.] -- Human monoclonal antibody and vaccine approaches to prevent human rabies / T. Nagarajan ... [et al.] -- Immunoprophylaxis of RSV infection: advancing from RSV-IGIV to palivizumab and motavizumab / H. Wu ... [et al.] -- The molecular basis of antibody protection against West Nile virus / E. Mehlhop ... [et al.] -- Exploring the native human antibody repertoire to create antiviral therapeutics / S. K. Dessain ... [et al.].
- Molecular epidemiology of human papillomavirus infection -- / Gillison, M.L -- Molecular pathogenesis of the human papillomavirus / Mao, C.-P., Wu, T.-C -- Human papillomavirus vaccines / Roden, R., Hung, C.-F., Monie, A., Wu, T.-C -- Hepatitis C virus genetics and the discovery of mechanism based inhibitors of the Ns3/4A protease and NS5B polymerase / LaFemina, R.L -- Role of the hepatitis B virus in hepatocellular carcinoma / Toh, S.-T., Lee, C.G -- Carcinogenesis induced by hepatitis B virus / Cougot, D., Buendia, M.-A., Neuveut, C -- Disease and pathogenesis associated with Epstein-Barr virus / Ambinder, R.F -- The biology and molecular biology underlying Epstein-Barr virus oncogenesis / Martin, H.J., Hayward, S.D -- Kaposi-sarcoma-associated herpesvirus clinical diseases and viral pathogenesis / Damania, B., Dittmer, D.P. -- Molecular biology of human herpesvirus 8 neoplasia / Chaudhary, P.M., Nicholas, J -- Human cancer viruses. Human T cell leukemia virus type 1 and 2: mechanisms of pathogenesis / Arnold, J., Green, P.L -- Chromosomal instability and human T cell leukemia virus 1 transformation / Chi, Y.-H., Jeang, K.-T.
- Human cytomegalovirus 2008SpringerHuman cytomegalovirus genome / E. Murphy and T. Shenk -- Human cytomegalovirus microRNAs / P.J. Fannin Rider ... [et al.] -- Mutagenesis of the cytomegalovirus genome / Z. Ruzsics and U.H. Koszinowski -- Cytomegalovirus cell tropism / C. Sinzger, M. Digel and G. Jahn -- Virus entry and innate immune activation / M.K. Isaacson, L.K. Juckem and T. Compton -- Functions of human cytomegalovirus tegument proteins prior to immediate early gene expression / R.F. Kalejta -- Initiation of cytomegalovirus infection at ND10 / G.G. Maul -- Functional roles of the human cytomegalovirus essential IE86 protein / M.F. Stinski and D.T. Petrik -- Nuts and bolts of human cytomegalovirus lytic DNA replication / G.S. Pari -- Interactions of human cytomegalovirus proteins with the nuclear transport machinery / T. Stamminger -- Structure and formation of the cytomegalovirus virion / W. Gibson -- Human cytomegalovirus modulation of signal transduction / A.D. Yurochko -- Chemokines and chemokine receptors encoded by cytomegaloviruses / P.S. Beisser ... [et al.] -- Subversion of cell cycle regulatory pathways / V. Sanchez and D.H. Spector -- Modulation of host cell stress responses by human cytomegalovirus / J.C. Alwine -- Control of apoptosis by human cytomegalovirus / A.L. McCormick -- Aspects of human cytomegalovirus latency and reactivation / M. Reeves and J. Sinclair -- Murine model of cytomegalovirus latency and reactivation / M.J. Reddehase ... [et al.] -- Cytomegalovirus immune evasion / C. Powers ... [et al.] -- Cytomegalovirus vaccine development / M.R. Schleiss -- Cytomegalovirus infection in the human placenta: maternal immunity and developmentally regulated receptors on trophoblasts converge / L. Pereira and E. Maidji -- Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing / D.N. Streblow ... [et al.] -- Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease / W. Britt.
- Human herpesvirus-6 general virology, epidemiology, and clinical pathology. 2nd ed. 2006ScienceDirect
- Development of the First AIDS Drugs: AZT and Other Dideoxynueosides / Robert Yarchoan, Hiroaki Mitsuya -- Part I: Structure and Function of HIV RT. Proviral DNA Synthesis in HIV: Background / Dorota Piekna-Przybylska Ph.D., Robert A. Bambara Ph.D. -- The RNase H Domain: Structure, Function and Mechanism / Marcin Nowotny, Małgorzata Figiel -- Conformational Dynamics of Reverse Transcription / Stuart F. J. LeGrice -- Part II: Mechanism of Action of Approved RT Inhibitors. Nucleoside RT Inhibitors: Structural and Molecular Biology / Gaofei Lu, Antonio J. Acosta-Hoyos, Walter A. Scott -- Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) / Kalyan Das Ph.D., Eddy Arnold Ph.D., Stephen H. Hughes Ph.D. -- Part III: Alternative Strategies to Interfere with the Function of HIV RT. Ribonuclease H Inhibitors: Structural and Molecular Biology / Jason W. Rausch -- Targeting Small Molecules and Peptides to the p66-p51 Reverse Transcriptase Interface / Daouda Abba Moussa, Audrey Agopian, Gilles Divita -- Targeting RT Translocation / Gregory L. Beilhartz, Brian J. Scarth, Matthias Götte -- tRNA Primer Sequestration as an Antiviral Strategy / Christopher P. Jones, Karin Musier-Forsyth -- Part IV: HIV Genetic Variability and the Problem of Drug Resistance. HIV Reverse Transcriptase Fidelity, Clade Diversity, and Acquisition of Drug Resistance / Luis Menéndez-Arias -- APOBECs and Their Role in Proviral DNA Synthesis / John S. Albin, Reuben S. Harris -- Role of RNase H Activity in NRTI/NNRTI Drug Resistance / Gilda Tachedjian B.Sc. (Hons), Ph.D., Nicolas Sluis-Cremer B.Sc. (Hons), Ph.D. -- HIV Population Dynamics / Mary Kearney, John Coffin -- Part V: Prevention and Future Approaches. RT Inhibitors as Microbicides / Jan Balzarini.
- Human Papilloma viruses 2002.ScienceDirect
- Human papillomaviruses methods and protocols 2005Springer ProtocolsAnalysis of HPV DNA replication using transient transfection and cell-free assays / Bing Yuan Lin, Thomas R. Broker, and Louise T. Chow -- Detection and quantitation of HPV DNA replication by southern blotting and real-time PCR / Iain M. Morgan and Ewan R. Taylor -- Analysis of E7/RB associations / Sandra Caldeira, Wen Dong, and Massimo Tommasino -- Transformation assays for HPV oncoproteins / Paola Massimi and Lawrence Banks -- Analysis of adeno-associated virus and hpv interaction / Paul L. Hermonat ... [et al.] -- In vitro assays of substrate degradation induced by high-risk HPV E6 oncoproteins / Miranda Thomas and Lawrence Banks -- Measuring the induction or inhibition of apoptosis by HPV proteins / Anna M. Kowalczyk ... [et al.] -- Codon optimization of papillomavirus genes / Martin Muller -- Generation of HPV pseudovirions using transfection and their use in neutralization assays / Christopher B. Buck ... [et al.] -- Generation and application of HPV pseudovirions using vaccinia virus / Martin Sapp and Hans-Christoph Selinka. Differentiation of HPV-containing cells using organotypic "raft" culture or methylcellulose / Regina Wilson and Laimonis A. Laimins -- Propagation of infectious, high-risk HPV in organotypic "raft" culture / Margaret E. McLaughlin-Drubin and Craig Meyers -- Retrovirus-mediated gene transfer to analyze HPV gene regulation and protein functions in organotypic "raft" cultures / N. Sanjib Banerjee, Louise T. Chow, and Thomas R. Broker -- The HPV xenograft severe combined immunodeficiency (scid) mouse model / William Bonner -- The cottontail rabbit papillomavirus model of high-risk HPV-induced disease / Janet L. Brandsma -- Studying the HPV lifecycle in 3A trophoblasts and resulting pathophysiology / Yong Liu, Hong You, and Paul L. Hermonat -- Replication and encapsidation of papillomaviruses in saccharomyces cerevisiae / Peter C. Angeletti -- Analysis of the regulation of viral transcription / Bernd Gloss, Mina Kalantari, and Hans-Ulrich Bernard -- Analysis of HPV transcripts by RPA / Jason M. Bodily and Craig Meyers -- Analysis of regulatory motifs within HPV transcripts / Sarah A. Cumming and Sheila V. Graham -- Detection of HPV transcripts by nested RT-PCR / Christine Mant, Barbara Kell, and John Cason -- Identification of new papillomavirus types / Ethel-Michele de Villiers, Corinna Whitley, and Karin Gunst -- Identification of HPV variants / John Cason, Jon Bible, and Christine Mant -- Histochemical analysis of cutaneous HPV-associated lesions / Kiyofumi Egawa -- Histochemical analysis of cervical intraepithelial neoplasia / Michael Babawale ... [et al.] -- Detection of papillomavirus proteins and DNA in paraffin-embedded tissue sections / Woei Ling Peh and John Doorbar -- Detection and quantitation of HPV gene expression using real-time PCR / Rashmi Seth ... [et al.] -- Analysis of P16INK4A and integrated genomes as progression markers / Svetlana Vinokurova, Nicolas Wentzensen, and Magnus von Knebel Doeberitz -- Use of biomarkers in the evaluation of CIN grade and progression of early CIN / Jan P.A. Baak and Arnold-Jan Kruse -- HPV DNA detection and typing in cervical scrapes / Peter J. F. Snijders ... [et al.] -- HPV DNA detection and typing in inapparent cutaneous infections and premalignant lesions / Maurits de Koning ... [et al.] -- Establishing HPV-containing keratinocyte cell lines from tissue biopsies / Margaret Anne Stanley -- Using an immortalized cell line to study the HPV lifecycle in organotypic "raft" cultures / Paul F. Lambert ... [et al.] --
- Human respiratory viral infections 2014CRCnetBASE
- Human viruses in water 2007ScienceDirect
- Influenza virus sialidase-- a drug discovery target 2012Springer
- Influenza. 1st ed. 2002ScienceDirect
- Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination. Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may result ineffective and, above all, may
- Intrinsic immunity 2013SpringerThe APOBEC3 Family of Retroelement Restriction Factors / Eric W. Refsland, Reuben S. Harris -- Inhibition of Retroviral Replication by Members of the TRIM Protein Family / Adam J. Fletcher, Greg J. Towers -- The Antiviral Activities of Tetherin / Stuart J. D. Neil -- Restriction of Retroviral Infection of Macrophages / Mark Sharkey -- Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors / Welkin E. Johnson -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants / György Szittya, József Burgyán -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates / Arabinda Nayak, Michel Tassetto, Mark Kunitomi, Raul Andino -- Roles of MicroRNAs in the Life Cycles of Mammalian Viruses / Eva Gottwein -- Interplay Between DNA Tumor Viruses and the Host DNA Damage Response / Karyn McFadden, Micah A. Luftig.
- Invasive fungal rhinosinusitis 2014SpringerIncidence of invasive fungal sinusitis has been increasing over the years. The understanding of its pathophysiology has improved with newer serological tests and diagnostic methods helping in earlier diagnosis and reducing patient morbidity. It was believed earlier that invasive fungal sinusitis is seen only in immune compromised patients but clinical reports suggest otherwise. More anti-fungal drugs are being added to improve incidence of patient survival. This book aims to compile all practical information about invasive fungal sinusitis into a single volume. Therefore, busy clinicians would not have to perform exhaustive literature studies to diagnose invasive fungal sinusitis. The book aims to provide an overview of diseases which could be mistaken for invasive fungal sinusitis and discuss how the management is different. Book sections consist of clinical, microbiological, serological, pathological, radiological and pharmacological features of the disease and its management. Each section is important in today's context as it dynamically alters the management of the patient. Early clinical suspicion and rapid microbiological, pathological and radiological diagnosis with aggressive treatment with surgical debridement and medical therapy leads to favorable outcomes.
- Print Material"He first full biography of Jonas Salk offers a complete picture of the enigmatic figure, from his early years working on an influenza vaccine--for which he never fully got credit--to his seminal creation of the Polio vaccine, up through his later work to find a cure for AIDS"-- Provided by publisher.
- Kaposi sarcoma herpesvirus new perspectives 2007SpringerModern evolutionary history of the human KSHV genome / G.S. Hayward and J.-C. Zong -- Rhesus monkey rhadinovirus : a model for the study of KSHV / C.M. O'Connor and D.H. Kedes --the Rta/Orf50 transactivator proteins of the gamma-herpesviridae / M.R. Staudt and D.P. Dittmer -- Structure and function of latency-associated nuclear antigen / S.C. Verma, K. Lan, and E. Robertson -- The KSHV and other human herpesviral G protein-coupled receptors / M. Cannon -- Regulation of KSHV lytic gene expression / H. Deng, Y. Liang, and R. Sun -- Karposi sarcoma herpesvirus-encoded interferon regulator factors / M.K. Offermann -- Endothelial cell- and lymphocyte-based in vitro systems for understanding KSHV biology / S.C. McAllister and A.V. Moses -- KSHV after an organ transplant : should we screen? / A.-G. Marcelin, V. Calvez, and E. Dussaix -- Kaposi sarcoma-associated herpesvirus and other viruses in human lymphomagenesis / E. Cesarman and E.A. Mesri -- The use of antiviral drugs in the prevention and treatment of Kaposi sarcoma, multicentric Castleman disease / C. Casper and A. Wald -- Interactions between HIV-1 Tat and KSHV / Y. Aoki and G. Tosato.
- Latency strategies of herpesviruses 2007Springer
- Lentiviral vectors and gene therapy 2012SpringerAnnotation Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale clinical trials to cure severe immunodeficiency in children. However, their successes were overshadowed some time later by the occurrence of vector-related leukaemia in a number of treated children. It is in this context that lentiviral vectors have appeared, with improved efficiency and, possibly, increased biosafety. Very recently, the first clinical trials with lentivectors have been carried out with some success. This Brief firstly defines gene therapy, and places lentivectors within this fascinating therapeutic strategy. Then follows a comprehensive description of the development of retroviral and lentiviral vectors and how to specifically target distinct cell types and tissues. The authors also discuss the application of lentivector gene therapy for the treatment of cancer and autoimmune diseases, ending with the application of lentivectors in human gene therapy clinical trials.
- Lentivirus gene engineering protocols 2003Springer Protocols
- Lesser known large dsDNA viruses 2009SpringerThe Phycodnaviridae : The story of how tiny giants rule the world / W.H. Wilson, J.L. Etten and M.J. Allen -- African swine fever virus / E.R. Tulman [and others] -- Mimivirus / J.M. Claverie, C. Abergel and H. Ogata -- Family Iridoviridae : poor viral relations no longer / V.G. Chinchar [and others] -- Ascoviruses: Superb Manipulators of Apoptosis for Viral Replication and Transmission / B.A. Federici [and others] -- Whispovirus / J.H. Leu [and others] -- Jumbo bacteriophages / R.W. Hendrix.
- Manual of security sensitive microbes and toxins 2014CRCnetBASESecurity sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants. Throughout history, these microbes and toxins have been exploited in one form or another as biowarfare and bioterror agents that create fear and panic well beyond any actual physical damages they might cause. Manual of Security Sensitive Microbes and Toxins provides comprehensive, state-of-the-art coverage of microbes and toxins of biosecurity concern.
- Membrane trafficking in viral replication 2005SpringerViral entry / S.B. Sieczarski and G.R. Whittaker -- The many mechanisms of viral membrane fusion proteins / L.J. Earp ... [et al.] -- The role of the cytoskeleton during viral infection / K. Döhner and B. Sodeik --Nuclear import in viral infections / U.F. Greber and M. Fornerod -- Viral RNA replication in association with cellular membranes / A. Salonen, T. Ahola, and L. Kääriäinen -- Synthesis and quality control of viral membrane proteins / C. Maggioni and I. Braakman -- Receptor modulation in viral replication : HIV, HSV, HHV-8 and HPV : same goal, different techniques to interface with MHC-I antigen presentation / V. Piguet -- Trafficking of viral membrane proteins / R. Byland and M. March.
- Models of viral hepatitis 2005KargerThe woodchuck: a model for immunopathogenesis and therapy of hepadnaviral infection / Roggendorf, M., Lu, M. -- Pathogenesis of hepatitis B virus in transgenic mice / Sitia, G. ... [et al.] -- Transfer of HBV genomes into mice / Oberwinkler, H. ... [et al.] -- Recent advances in the duck hepatitis B virus model of human hepatitis B virus infection / Jilbert, A.R. -- Determinants of hepadnaviral species and liver cell tropism / Funk, A. ... [et al.] -- T-cell response to hepatitis B virus and hepatitis C virus: lessons learned from the chimpanzee model / Thimme, R. ... [et al.] -- The replicon system as an efficient tool to study HCV RNA replication / Lohmann, V. -- Hepatitis B virus infection of primary tupaia hepatocytes / Kück, J., Glebe, D. -- Tupaia belangeri as a model for hepatitis C virus infection / Baumert, T. ... [et al.] -- Primary human hepatocytes as an in vitro model for hepatitis B virus infection / Boehm, S. ... [et al.] -- Progress and perspectives of the uPA/RAG-2 mouse model: liver repopulation and viral infection studies / Dandri, M. ... [et al.] -- The trimera mouse model of HBV and HCV infection / Bücher, W.O., Reisner, Y.
- Viruses and the innate immune system / Megan L. Shaw, Peter Palese -- How viruses elicit interferon production / David E. Levy, Isabelle J. Marié -- Gene modulated by interferons and double-stranded RNA / Saumendra N. Sarkar, Gregory A. Peters, Ganes C. Sen -- Immunoevasive strategies: host and virus / Markus Wagner, Shahram Misaghi, Hidde L. Ploegh -- Interferon antagonists of influenza viruses / Adolfo Garcia-Sastre -- The anti-interferon mechanisms of paramyxoviruses / Nicola Stock, Stephen Goodbourn, Richard E. Randall -- The strategy of conquest / Sunil J. Advani, Bernard Roizman -- Immunomodulation by poxviruses / James B. Johnston, Grant McFadden -- Interferon antagonists encoded by emerging RNA viruses / Christopher F. Basler -- Viral pathogenesis and toll-like receptors / Susan R. Ross -- Digesting oneself and digesting microbes / Montrell Seay, Savithramma Dinesh-Kumar, Beth Levine -- Genetic variation in host defenses and viral infections / Eunhwa Choi, Stephen J. Chanock.
- This book focuses on the function of antibodies in vivo. Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. These new results dramatically changed our view of how antibodies function in vivo. The importance of this class of molecules is demonstrated by the heightened susceptibility to infections of humans and mice with an altered capacity to generate pathogen specific antibody responses. Thus, the majority of our currently available vaccines, such as vaccines against influenza, measles and hepatitis focus on the generation of long lasting antibody responses. Recent evidence from a variety of in vivo model systems and from human patient cohorts has highlighted the exclusive role of cellular Fc-receptors for certain immunoglobulin isotypes and subclasses. With the recent discovery of a human Fc-receptor for IgM all different human immunoglobulin isotypes now have a cellular receptor, providing a feedback mechanism and link between antibodies and the cellular components of the immune system. Moreover it has become clear the complement and Fc-receptor system are tightly connected and regulate each other to ensure a well balanced immune response. Among the immunoglobulin isotypes IgG plays a very important protective role against microbial infections and also as a therapeutic agent to kill tumor cells or autoantibody producing B cells in autoimmune disease. Transfer of our knowledge about the crucial function of Fc-receptors has led to the production of a second generation of therapeutic antibodies with enhanced binding to this class of receptors. Binding of antibodies to Fc-receptors leads to the recruitment of the potent pro-inflammatory effector functions of cells from the innate immune system. Hence, Fc-receptors link the innate and adaptive immune system, emphasizing the importance of both arms of the immune system and their crosstalk during anti-microbial immune responses. Besides this pro-inflammatory activity immunoglobulin G (IgG) molecules are long known to also have an anti-inflammatory function. This is demonstrated by the use of high dose intravenous immunoglobulins as a therapeutic agent in many human autoimmune diseases. During the past five years several new insights into the molecular and cellular pathways of this anti-inflammatory activity were gained radically changing our view of IgG function in vivo. Several lines of evidence suggest that the sugar moiety attached to the IgG molecule is responsible for these opposing activities and may be seen as a molecular switch enabling the immune system to change IgG function from a pro- to an anti-inflammatory activity. There is convincing evidence in mice and humans that aberrant IgG glycosylation could be an important new pathway for understanding the impaired antibody activity during autoimmune disease. Besides this tremendous increase in basic knowledge about factors influencing immunoglobulin activity the book will also provide insights into how these new insights might help to generate novel therapeutic approaches to enhance IgG activity for tumor therapy on the one hand, and how to block the self-destructive activity of IgG autoantibodies during autoimmune disease on the other hand.
- Molecular biology of the SARS-coronavirus 2010SpringerThe SARS outbreak in 2002 caused unprecedented devastation and exhibited unusually high rates of morbidity and mortality. For the SARS coronavirus, the transmission vehicle was man. What added to the spread was man's convenient, rapid and affordable ways of travel that caused the virus to spread globally in a short span of time. The SARS coronavirus jumped the species barrier, similar to many recent zoonotic diseases, avian flu, swine flu, Nipah and encephalitis virus. It is extremely important for us to understand the enemy before it strikes again in order to be able to combat such outbreaks as and when they occur. Molecular mechanisms that the virus exploits within its host and that result in infection and pathogenesis are the key to being able to block its transmission cycle. In this book, leading scientists from around the globe have discussed molecular aspects of viral entry, replication, viral gene expression, pathogenesis and host immune response against the SARS coronavirus.
- Molecular virology 2013SpringerThe book gives a comprehensive overview on the knowledge of virus infection relevant for humans and animals. For each virus family the molecular details of the virus particle and the viral replication cycle are described. In the case of virus types with relevance for human and/or animal health the data on molecular biology, genetics and virus-cell interaction are combined with those concerning, pathogenesis, epidemiology, clinics, prevention and therapy.
- Mosquito vectors of Japanese encephalitis virus from Northern India role of BPD hop cage method 2013SpringerJapanese Encephalitis (JE), a mosquito borne disease, is the leading cause of viral encephalitis in 14 Asian countries due to its epidemic potential, high case fatality rate and increased possibility of lifelong disability in patients who recover from this dreadful disease. In spite of seriousness of the disease, still only few books are available for ready reference. Hence, this book will be useful for students, entomologists, paramedical staff and vector control managers in public health.Of the thousand suspected JE deaths in India annually, more than 75% is contributed by Northern India wherein disease transmission failed to be explained based on entomological evidence due to inadequate mosquito surveillance tool used in determining JE vector density. In order to overcome the above problem, Dr Bina Pani Das, the author of this book, developed "BPD hop cage method", a simple, cost effective, and operationally feasible surveillance tool specially designed to capture predominantly day resting adult Cx. tritaeniorhynchus mosquitoes, the principal JE vector species in the country from land and aquatic vegetation.
- Mucosal immunology and virology 2006SpringerThe role of mucosal immunity in protection against viral diseases / Vandana Madkan, Karan Sra, and Stephen K. Tyring -- Anogenital mucosal immunology and virology / Anthony Simmons -- Gastrointestinal mucosal immunology / David A. Bland, Carlos A. Barrera, and Victor E. Reyes -- Virology of the gastrointestinal tract / Richard L. Ward ... [et al.] -- Oral manifestations of viral diseases / Denis P. Lynch -- Common respiratory viruses and pulmonary mucosal immunology / David B. Huang -- Ophthalmic manifestations of viral diseases / Steven Yeh and Mitchell P. Weikert.
- Neuroviral infections. General principles and DNA viruses / 2013CRCnetBASENeuroviral infections : a historical perspective -- Neuroviral infections and immunity -- Controlling neuroinflammation : lessons from rabies virus -- Laboratory diagnosis of CNS viral infections -- New trends in antiviral therapy of CNS infections -- Animal models of viral encephalitis -- Herpes simplex virus and human CNS infections -- CNS, neurological infections caused by the herpes virus Varicella zoster virus (VZV) and models of VZV-neurotropism -- Epstein- Barr virus and CNS infections -- Cytomegalovirus (CMV) infection -- Human herpesvirus 6A, 6B, and 7 encephalitis -- The human polyomavirus JC and progressive multifocal leukoencephalopathy.
- Neuroviral infections. RNA viruses and retroviruses / 2013CRCnetBASEAlphavirus neurovirulence -- Neurological chikungunya : lessons from recent epidemics, animal models, and other alphavirus family members -- Arenaviruses and neurovirology -- Bunyaviruses -- Human coronaviruses : respiratory pathogens revisited as infectious neuroinvasive, neurotropic, and neurovirulent agents -- Non-polio enteroviruses, polioviruses, and human CNS infections -- Neurovirulence of West Nile Virus -- Murray Valley encephalitis virus -- Japanese encephalitis virus and human CNS infection -- Tick Borne Encephalitis Virus (TBEV) infection -- Saint Louis encephalitis -- Powassan virus infection -- Neurological Dengue -- Influenza virus and CNS infections -- Human paramyxoviruses and infections of the central nervous system -- Rabies virus neurovirulence -- Rubella virus infections -- Human T-lymphotropic virus -- Human Immunodeficiency Virus (HIV) neuropathogenesis.
- Neurovirology 2014ScienceDirectThis volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology. Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere.
- Viral RNA synthesis -- Protein synthesis, structure, and processing -- Viral assembly and release -- Viral entry -- Pathogenesis of non-human coronaviruses -- Pathogenesis of arteriviruses and toroviruses -- Pathogenesis of human coronaviruses -- Vaccines, antiviral drugs, and diagnostics.
- One Health: the human-animal-environment interfaces in emerging infectious diseases. Food safety and security, and international and national plans for implementation of One Health activities 2013SpringerThe second volume on One Health explains in detail how to implement three key aspects of the One Health paradigm food safety and security, national plans for a holistic one health approach, and relevant new technologies and approaches. The fourteen chapters, each by an internationally recognized authority, are organized into three sections of four or five chapters each, that break new ground in clarifying precisely how One Health can become an operational reality in local, national and international public health initiatives. Section three begins with an international overview on food safety and security. The importance of a One Heath approach is then explained in relation to four specific problems?the growing prevalence of antibiotic resistance, bovine spongiform encephalopathy and pathogenic E.coli. Section four begins with the role of the Food and Agricultural Organization (FAO) in promoting One Health. The formulation and implementation of national plans for implementing the One Health paradigm are then set out for Africa, the Western Pacific, Southeast Asia and Mongolia. The final section of this two volume book is devoted to implementing new technologies and new approaches to One Health. A wide-ranging analysis considers the importance of climate change and a social-ecological systems approach, as well as how to operationalize One Health, how to move from emergency response to prevention at source, and how to implement an educational strategy that builds a foundation for One Health in emerging disease management. It is anticipated that this two volume book will become a benchmark for practitioners of One Health, empowering a balanced multidisciplinary approach to the complexities of the human-animal-environment interface.
- Papillomaviruses 2007Springer
- Parasitoid viruses symbionts and pathogens. 1st ed. 2012ScienceDirect"Parasitoids are parasitic insects that kill their insect hosts in immature pre-reproductive stages. Parasitoids are employed in biological control programs worldwide to kill insect pests and are environmentally safe and benign alternatives to chemical pesticides. As resistance to chemical pesticides continues to escalate in many pest populations, attention is now refocusing on biologically based strategies to control pest species in agriculture and forestry as well as insect vector populations that transmit human and animal diseases. Parasitoids are an economically critical element in this equation and in integrated pest management. Viruses have evolved intimate associations with parasitoids, and this book features a large section on symbiotic viruses that are integrated into the wasp chromosomal DNA (polydnaviruses). A separate section on parasitoid venoms, which are of interest to the pharmaceutical and medical communities as well as insect-oriented biologists, is also featured"--Back cover.
- Planctomycetes cell structure, origins and biology 2013SpringerHistory, classification and cultivation of the planctomycetes / Cheryl Jenkins and James T. Staley -- Cell compartmentalization and endocytosis in planctomycetes: structure and function in complex bacteria / John A. Fuerst, Richard I. Webb, and Evgeny Sagulenko -- Structural aspects of MC proteins of PVC superphylum members / Damien P. Devos -- Cell biology of anaerobic ammonium-oxidizing bacteria: unique prokaryotes with an energy-conserving intracellular compartment / Sarah Neumann, Muriel C.F. van Teeseling and Laura van Niftrik -- Acidophilic planctomycetes: expanding the horizons of new planctomycete diversity / Svetlana N. Dedysh and Irina S. Kulichevskaya -- Toward the development of genetic tools for Planctomycetes / Mareike Jogler and Christian Jogler -- Genomics and bioinformatics of the PVC superphylum / Olga K. Kamneva, Daniel H. Haft, Stormy J. Knight, Davide A. Liberles, and Naomi L. Ward -- Distribution and evolution of C1 transfer enzymes and evolution of the planctomycetes / Ludmila Chistoserdova -- Unusual members of the PVC superphylum: the methanotrophic Verrucomicrobia genus "Methylacidiphilum" / Christine E. Sharp, Huub J.M. Op den Camp, Ivica Tamas, and Peter F. Dunfield -- Phyla related to Planctomycetes: members of phylum Chlamydiae and their implications for Planctomycetes cell biology / Claire Bertelli and Gilbert Greub -- Planctomycetes: their evolutionary implications for models for origins of eukaryotes and the eukaryote nucleus and endomembranes / John A. Fuerst and Evgeny Sagulenko -- Final word: the future of planctomycetology and related studies / John A. Fuerst -- Index.
- Plant virology protocols from viral sequence to protein function. 2nd ed. 2008Springer Protocols
- Polyomaviruses and human diseases 2006SpringerPolyomaviruses and human diseases / Nasimul Ahsan and Keerti V. Shah -- Discovery and epidemiology of the human polyomaviruses BK virus (BKV) and JC virus (JCV) / Wendy A. Knowles -- Phylogenomics and molecular evolution of polyomaviruses / Keith A. Crandall ... [et al.] -- Virus receptors and tropism / Aarthi Ashok and Walter J. Atwood -- Serological cross reactivity between polyomavirus capsids / Raphael P. Viscidi and Barbara Clayman -- Molecular genetics of the BK virus / Christopher L. Cubitt -- Serological diagnosis of human polyomavirus infection / Annika Lundstig and Joakim Dillner -- Human polyomavirus JC and BK persistent infection / Kristina Doerries -- Immunity and autoimmunity induced by polyomaviruses / Ole Petter Rekvig, Signy Bendiksen, and Ugo Moens -- The pathobiology of polyomavirus virus infection in man / Parmjeet Randhawa, Abhay Vats, and Ron Shapiro -- Polymoavirus-associated nephropathy in renal transplantation / Hans H. Hirsch ... [et al.] -- BK virus and immunosuppressive agents / Irfan Agha and Daniel C. Brennan -- BK virus infection after non-renal transplantation / Martha Pavlakis, Abdolreza Haririan, and David K. Klassen -- Latent and productive polyomavirus infections of renal allografts / Volker Nickeleit, Harsharan K. Singh, and Michael J. Mihatsch -- Urine cytology findings of polyomavirus infections / Harsharan K. Singh ... [et al.] -- Diagnosis and treatment of BK virus-associated transplant nephropathy / Abhay Vats, Parmjeet S. Randhawa, and Ron Shapiro -- Pharmacotherapeutic options for the management of human polyomaviruses / Julie Roskopf ... [et al.] -- Leflunomide in solid organ transplantation and polyoma virus infection / Michelle A. Josephson ... [et al.] -- JC virus can infect human immune and nervous system progenitor cells / Jean Hou, Pankaj Seth, and Eugene O. Major -- The polyomavirus, JCV, and its involvement in human disease / Kamel Khalili, Jennifer Gordon, and Martyn K. White -- Transforming activities of JC virus early proteins / Richard J. Frisque, Catherine Hofstetter, and Shiva K. Tyagarajan -- Polyomavirus in human cancer development / Winston Lee and Erik Langhoff -- BK virus, JC virus, and simian virus 40 infection in humans and association with human tumors / Giuseppe Barbanti-Brodano ... [et al.] -- Epidemiologic studies of polyomaviruses and cancer / Dana E.M. Rollison.
- Poxviruses 2007Springer
- Practical guidelines in antiviral therapy. 1st ed. 2002ScienceDirect
- Virology and pathogenesis / Pfister, H. -- Epidemiology of mucosotropic papillomaviruses / Gissmann, L. -- Condylomata acuminata / Gross, G. -- Recurrent respiratory papillomatosis / Wittekindt, C.; Wagner, S.; Klussmann, J.P. -- Cervical cancer and intraepithelial neoplasia / Schneider, A. ... [et al.] -- Cancer and intraepithelial neoplasia of the vulva and vagina / Petry, K.U. -- Penile cancer and penile intraepithelial neoplasia / Gross, G. -- Anal cancer and intraepithelial neoplasia / Wieland, U. ; Kreuter, A. -- Tonsillar cancer / Klussmann, J.P.; Wagner, S.; Wittekindt, C. -- Cytology / Ikenberg, H. -- Concepts of biomarker development / von Knebel Doeberitz, M.; Vinokurova, S.; Reuschenbach, M. -- Detection of human papillomavirus DNA and RNA / Ikenberg, H. -- Human papillomavirus testing in primary screening for cervical cancer / Petry, K.U. -- Primary prevention by vaccination / Kaufmann, A.M.; Gissmann, L.
- Quasispecies concept and implications for virology 2006Springer
- Rabies-- scientific basis of the disease and its management. Third edition. [3rd ed.] 2013ScienceDirectHistory of rabies research -- Rabies virus -- Epidemiology -- Molecular epidemiology -- Rabies in terrestrial animals -- Bat rabies -- Human disease -- Pathogenesis -- Pathology -- Immunology -- Laboratory diagnosis of rabies -- Measures of rabies immunity -- Rabies vaccines -- Next generation of rabies vaccines -- Public health management of humans at risk -- Therapy of human rabies -- Dog rabies and its control -- Rabies control in wild carnivores -- Blueprint for rabies prevention and control -- Future developments and challenges.
- Reoviruses entry, assembly and morphogenesis 2006SpringerAttachment and cell entry of mammalian orthoreovirus / K.M. Guglielmi ... [et al.] -- Early steps in rotavirus cell entry / S. Lopez and C.F. Arias -- Early steps in avian reovirus morphogenesis / J. Benavente and J. Martinez-Costas -- Bluetongue virus assembly and morphogenesis / P. Roy and R. Noad -- Reovirus structure and morphogenesis / K.M. Coombs -- Rotavirus genome replication and morphogenesis : role of the viroplasm / J.T. Patton ... [et al.] -- Rotavirus proteins : structure and assembly / J.B. Pesavento ... [et al.] --- Structural studies on orbivirus proteins and particles / D.I. Stuart and J.M. Grimes -- Rotavirus assembly : an alternative model that utilizes and atypical trafficking pathway / S. Chwetzoff and G. Trugnan.
- Respiratory syncytial virus. 1st ed. 2007ScienceDirect
- Respiratory virology and immunogenicity 2015SpringerThis volume provides a modern look on the age-old influenza infection and the preventive role of anti-influenza shots. Influenza pandemic outbreaks are unrelenting despite the growing understanding of the molecular basis of viral infection and its spreads. A leap in medical technologies has revolutionized the design of new influenza vaccines. The chapters cover vaccination strategies in various age-groups of people and provide the extensive amount of knowledge on the immune response to influenza vaccination in a spectrum of disease conditions.
- Harrison's Principles of Internal Medicine
- AAP Red Book Online
- Robbins & Cotran Pathologic Basis of Disease
- Sabiston Textbook of Surgery
- Nelson's Textbook of Pediatrics
- Surgical Exposures in Orthopaedics
- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
- Red Book Online
- ICU Book
- Primary Care Medicine
- Campbell-Walsh Urology
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