Books by Subject
- 2014 Springer Protocolsedited by Miguel Chillón, Assumpció Bosch.Biophysical methods to monitor structural aspects of the adenovirus infectous cycle / Rosa Menéndez-Conejero ... [et al.] -- Proteome analysis of adenovirus using mass spectrometry / Sara Bergström Lind, Konstantin A. Artemenko, and Ulf Pettersson -- Capsid modification strategies for detargeting adenoviral vectors / Alan L. Parker ... [et al.] -- Use of dodecahedron "VLPs" as an alternative to the whole adenovirus / Pascal Fender -- Study of adenovirus and CAR axonal transport in primary neurons / Charleine Zussy and Sara Salinas -- The use of chromatin immunoprecipitation (hIP) to study the binding of viral proteins to the adenovirus genome in vivo / Yueting Zheng and Patrick Hearing -- DNA microarray to analyze adenovirus-host interactions / Stefania Piersanti, Enrico Tagliafico, and Isabella Saggio -- Determination of the transforming activities of adenovirus oncogenes / Thomas Speiseder, Michael Nevels, and Thomas Dobner -- Oncolytic adenovirus characterization : activity and immune responses / Raul Gil-Hoyos, Juan Miguel-Camacho, and Ramon Alemany -- The analysis of innate immune response to adenovirus using antibody arrays / Nelson C. Di Paolo and Dmitry M. Shayakhmetov -- Engineering adenovirus genome by bacterial artificil chromosome (BAC) technology / Zsolt Ruzsics, Frederic Lemnitzer, and Christian Thirion -- Construction, production, and purification of recombinant adenovirus vectors / Susana Miravet ... [et al.] -- Sealable production of adenovirus vectors / Ana Carina Silva ... [et al.] -- Canine adenovirus downstream processing protocol / Meritxell Puig ... [et al.] -- Production of high-capacity adenovirus vectors / Florian Kreppel -- Production of chimeric adenovirus / Marta Miralles ... [et al.]
- 2013 SpringerEric O. Freed, editor.Over the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle. This has been made possible by major advances in cell biology, virology, and structural biology. The field continues to move forward rapidly, with important new discoveries being reported on a regular basis. The impact of this progress across a broad spectrum of biomedical research has been substantial. The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research. The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.
- 2014 Springer Protocolsedited by Erica Spackman, Exotic and Emerging Avia Viral Diseases Unit, Southeast Poultry Research Laboratory, US Department of Agriculture, Agricultural Research Service, Athens, GA, USA.Hemagglutination assay for influenza virus / Mary Lea Killian -- Hemagglutination-inhibition assay for influenza virus subtype identification and the detection and quantitation of serum antibodies to influenza virus / Janice C. Pedersen -- Neuraminidase-inhibition assay for the identification of influenza A virus neuraminidase virus subtype or neuraminidase antibody specificity / Janice C. Pedersen -- Reverse genetics of influenza virus / Chang-Won Lee -- Immunohistochemical staining of influenza virus in tissues / Mary J. Pantin-Jackwood -- A brief introduction to avian influenza virus / Erica Spackman -- Wild bird surveillance for avian influenza virus / Justin D. Brown, Rebecca Poulson, and David E. Stallknecht -- Avian influenza virus sample types, collection, and handling / Mary Lea Killian -- Avian influenza virus RNA extraction / Erica Spackman and Scott A. Lee -- Avian influenza virus detection and quantitation by real-time RT-PCR / Erica Spackman -- Influenza subtype identification with molecular methods / Erica Spackman -- Avian influenza virus isolation, propagation, and titration in embryonated chicken eggs / Erica Spackman and Mary Lea Killian -- Agar gel immunodiffusion assay to detect antibodies to type A influenza virus / Terra A. Jenson -- Detection of influenza A antibodies in avian serum samples by ELISA / Len Chappell, Mary Lea Killian, and Erica Spackman -- Conducting influenza virus pathogenesis studies in avian species / Carol J. Carona [and three others] -- Laboratory methods for assessing and licensing influenza vaccines for poultry / David E. Swayne -- Detection of cell-mediated immune response to avian influenza viruses / Darrell R. Kapczynski -- Characterization of cytokine expression induced by avian influenza virus infection with realt-time RT-PCR / Darrell R. Kapczynski, Hai Jun Jiang, and Michael H. Kogut -- Newcastle disease virus detection and differentiation from avian influenza / Patti J. Miller and Mia Kim Torchetti -- A brief introduction to influenza A virus in swine / Amy L. Vincent, Kelly M. Lager, and Tavis K. Anderson -- Sample types, collection, and transport for influenza A viruses of swine / Marie R. Culhane and Susan E. Detmer -- Isolation of swine influenza virus in cell cultures and embryonated chicken eggs / Jianqiang Zhang and Phillip C. Gauger -- RNA extraction from swine samples and detection of influenza A virus in swine by real-time RT-PCR / Jianqiang Zhang and Karen M. Harmon -- Hemagglutinin inhibition assay with swine sera / Pravina Kitikoon, Phillip C. Gauger, and Amy L. Vincent -- Enzyme-linked immunosorbent assay for detection of serum or mucosal isotype-specific IgG and IgA whole-virus antibody to influenza A virus in swine / Phillip C. Gauger, Crystal L. Loving, and Amy L. Vincent -- Serum virus neutralization assay for detection and quantitation of serum-neutralizing antibodies to influenza A virus in swine / Phillip C. Gauger and Amy L. Vincent -- Microneutralization assay for swine influenza virus in swine serum / Pravina Kitikoon and Amy L. Vincent -- Analyzing swine sera for functional antibody titers against influenza A neuraminidase proteins using an enzyme-linked lectin assay (ELLA) / Matthew R.Sandbulte and Maryna C. Eichelberger -- Antibody secreting cell assay for influenza A virus in swine / Pravina Kitikoon, Crystal L. Loving, and Amy L. Vincent -- In vivo models for pathotyping and vaccine efficacy for swine influenza / Kelly M. Lager and Amy L. Vincent -- A brief introduction to equine influenza and equine influenza viruses / Thomas M. Chambers -- Equine influenza diagnosis : sample collection and transport / Thomas M. Chambers and Stephanie E. Reedy -- RNA extraction from equine samples for equine influenza virus / Udeni B.R. Balasuriya -- Type A influenza virus detection from horses by real-time RT-PCR and insulated isothermal RT-PCR / Udeni B.R. Balasuriya -- Equine influenza culture methods / Thomas M. Chambers and Stephanie E. Reedy -- Equine influenza serological methods / Thomas M. Chambers and Stephanie E. Reedy.
- Includes information on antimicrobial therapy and alternative therapy when the drug of choice cannot be given. The resource delivers information via review articles, capsule summaries, mini-reviews, and a guided PubMed search to pick up post-publication research.
- 2013 Springer Protocolsedited by Edwin Yunhao Gong.Part I Human immunodeficiency virus type 1 (HIV-1) -- Fluorescence-based high-throughput screening assay to identify HIV-1 inhibitors / Peggy Geluykens ... [et al.] -- Homogeneous time-resolved fluorescence assay to identify inhibitors of HIV-1 fusion / Liesbet Smeulders ... [et al.] -- Identification of HIV-1 reverse transcriptase inhibitors using a scintillation proximity assay / Bertrand Van Schoubroeck ... [et al.] -- Biochemical screening assays to identify HIV-1 integrase inhibitors / Marleen Clynhens ... [et al.] -- HIV-1 genotyping of the protease-reverse transcriptase and integrase genes to detect mutations that confer antiretroviral resistance / Peter Van den Eede ... [et al.] -- Part II Hepatitis viruses -- In vitro kinetic profiling of hepatitis C virus NS3 protease inhibitors by progress curve analysis / Rumin Zhang and William T. Windsor -- Novel hepatitis C virus NS5B polymerase assay of de novo initiated RNA synthesis directed from a heteropolymeric RNA template / Eric Ferrari and Hsueh-Cheng Huang -- Selecting and characterizing drug-resistant hepatitis C virus replicon / Inge Vliegen, Leen Delang, and Johan Neyts -- Cellular replicon-based phenotyping assay to determine susceptibility of hepatitis C virus clinical isolates to NS3/4A protease inhibitors / Leen Vijgen ... [et al.] -- Expression and purification of hepatitis C virus protease from clinical samples / Liesbet van der Helm -- Surface plasmon resonance as a tool to select potent drug candidates for hepatitis C virus NS5B polymerase / Erna Cleiren, Benoit Devogelaere, and Katleen Fierens -- Amplification and sequencing of the hepatitis C virus NS3/4A protease and the NS5B polymerase regions for genotypic resistance detection of clinical isolates of subtypes 1a and 1b / Diana Koletzki ... [et al.] -- Southern blot assay for detection of hepatitis B virus covalently closed circular DNA from cell cultures / Dawei Cai ... [et al.] -- In vitro phenotyping of recombinant hepatitis B virus containing the polymerase/reverse transcriptase gene from clinical isolates / Yang Liu and Kathryn M. Kitrinos -- Part III Flaviviruses -- Cell-based antiviral assays for screening and profiling inhibitors against dengue virus / Edwin Yunhao Gong ... [et al.] -- Duplex real-time RT-PCR assay for profiling inhibitors of four dengue serotypes / Edwin Yunhao Gong ... [et al.] -- High-throughput screening using dengue virus reporter genomes / Wolfgang Fischl and Ralf Bartenschlager -- Fluorimetric and HPLC-based dengue virus protease assays using a FRET substrate / Christoph Nitsche and Christian D. Klein -- Expression and purification of dengue virus NS5 polymerase and development of a high-throughput enzymatic assay for screening inhibitors of dengue polymerase / Edwin Yunhao Gong ... [et al.] -- Detection and quantification of flavivirus NS5 methyl- transferase activities / Siew Pheng Lim, Christophe Bodenreider, and Pei-Yong Shi -- Testing antiviral compounds in a dengue mouse model / Wouter Schul, Andy Yip, and Pei-Yong Shi -- Construction of self-replicating subgenomic west nile virus replicons for screening antiviral compounds / Sofia L. Alcaraz-Estrada, Erin Donohue Reichert, and Radhakrishnan Padmanabhan -- Part IV Herpes viruses -- Methods for screening and profiling inhibitors of herpes simplex viruses / Edwin Yunhao Gong -- In vivo evaluation of antiviral efficacy against genital herpes using mouse and guinea pig models / Frances Valencia, Ronald L. Veselenak, and Nigel Bourne -- Fluorescence-based high-throughput screening assay for identifying human cytomegalovirus inhibitors / Christel Van den Eynde ... [et al.] -- Part V Respiratory viruses -- Fluorescence-based high-throughput antiviral compound screening assay against respiratory syncytial virus / Leen Kwanten, Ben De Clerck, and Dirk Roymans -- Screening and evaluation of anti-respiratory syncytial virus compounds in cultured cells / Anna Lundin, Tomas Bergström, and Edward Trybala -- Evaluation of antiviral efficacy against human respiratory syncytial virus using cotton rat and mouse models / Joke Van den Berg, Leen Kwanten, and Dirk Roymans -- In vivo evaluation of antiviral compounds on respiratory syncytial virus using a juvenile vervet monkey (Chlorocebus pygerythrus) infection model / Lieselot Houspie ... [et al.] -- Methods to determine mechanism of action of anti-influenza inhibitors / Angela Luttick, Stephanie Hamilton, and Simon P. Tucker -- Methods for evaluation of antiviral efficacy against influenza virus infections in animal models / Donald F. Smee and Dale L. Barnard -- Part VI Alphaviruses -- Development of a high-throughput antiviral assay for screening inhibitors of chikungunya virus and generation of drug-resistant mutations in cultured cell / Edwin Yunhao Gong ... [et al.] -- Mouse model of chikungunya virus with utility in antiviral studies / Ashley Dagley and Justin G. Julander.
- 2012 Springer Protocolsedited by John M. Watson and Ming-Bo Wang.Historical overview of RNAi in plants / John A. Lindbo -- RNA silencing and antiviral defense in plants / Claire Agius [and others] -- Biological chemistry of virus-encoded suppressors of RNA silencing : an overview / Rustem T. Omarov and Herman B. Scholthof -- Virus-induced gene silencing using begomovirus satellite molecules / Xueping Zhou and Changjun Huang -- Strategies for viral cross protection in plants / Changyong Zhou and Yan Zhou -- Tobacco rattle virus (TRV)-based virus-induced gene Silencing / Shawn Bachan and Savithramma P. Dinesh-Kumar -- Virus-induced gene silencing in hexaploid wheat using barley stripe mosaic virus vectors / Steven R. Scofield and Amanda S. Brandt -- Characterization of plant virus-encoded gene silencing suppressors / Hajime Yaegashi, Masamichi Isogai, and Nobuyuki Yoshikawa -- Generation of plant small RNA cDNA libraries for high-throughput sequencing / Qian-Hao Zhu and Christopher A. Helliwell -- Modeling antiviral resistance in plants / Robert S. Anderssen and Peter M. Waterhouse -- Isolation and detection of small RNAs from plant tissues / Neil A. Smith and Andrew L. Eamens -- Isolation and analysis of small RNAs from virus-infected plants / Shaun J. Curtin [and others] -- Use of hairpin RNA constructs for engineering plant virus resistance / Neena Mitter and Ralf G. Dietzgen -- Artificial microRNAs for plant virus resistance / Jing Qu, Jian Ye, and Rongxiang Fang -- Isolation and biochemical analysis of plant small RNAs / H. Alexander Ebhardt, Mariana Oviedo Ovando, and Peter J. Unrau -- Isolation and analysis of plant RNA-dependent RNA polymerases / Julien Curaba -- Plant viroids : isolation, characterization/detection, and analysis / Robert A. Owens, Teruo Sano, and Nuria Duran-Vila -- Structural and functional analysis of CMV satellite RNAs in RNA silencing / Hanako Shimura and Chikara Masuta -- Virus-Induced Gene Silencing in Soybean / Aardra Kachroo and Said Ghabrial -- Chimeric, infectious, and stable virus transcripts to study RNA silencing in "Dark Green" Islands / Robin M. MacDiarmid -- Rolling circle amplification-mediated long hairpin RNA library construction in plants / Lei Wang and Yun-Liu Fan -- Interaction between plant viroid-induced symptoms and RNA silencing / Vicente Pallas, German Martinez, and Gustavo Gomez -- Identification of small molecule inhibitors of tomato bushy stunt virus replication / Zsuzsanna Sasvari and Peter D. Nagy -- Expression of dominant-negative mutants to study host factors affecting plant virus infections / Daniel Barajas and Peter D. Nagy.
- 2011 Springer Protocolsedited by Ronald P. van Rij.[Publisher-supplied data] Viruses and RNAi share an intricate relationship at many levels. RNAi is an important antiviral defense mechanism in plants and invertebrates, microRNAs of viral or cellular origin affect many aspects of virus biology, and replication of many, if not all, mammalian viruses can be suppressed by RNAi. Antiviral RNAi: Concepts, Methods, and Applications provides a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for the development and optimization of RNAi-based antiviral drugs. As RNAi is a central regulatory mechanism in the cell, the methods in this volume can also be applied out of the context of a virus infection. Divided into five convenient parts, this detailed volume reviews important basic concepts in the field of antiviral RNAi, provides experimental and bio-informatic tools for the analysis of small silencing RNAs, covers methods to biochemically dissect RNAi-based antiviral defense and viral counter-defense mechanisms, describes methods for the design, expression, and delivery of therapeutic antiviral siRNAs, and finally presents genome-wide RNAi approaches for the identification of factors involved in virus replication. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Antiviral RNAi: Concepts, Methods, and Applications serves as an ideal guide for both novice and experienced researchers alike striving to dissect the role of RNAi in the viral life cycle or to further boost the development of novel therapeutics and experimental tools based on RNAi technology.
- 2013 SpringerStacey Schultz-Cherry, editor.Since their initial discovery in the 1970's, astroviruses have been recognized as a leading cause of enteritis in infants, the elderly, and immunocompromised people, and were known to be widespread in animals and birds. In recent years, and with the advent of pyrosequencing, there has been a virtual explosion in the number of newly identified astrovirus genotypes. With this has come an increased understanding in astrovirus biology, structure, epidemiology, immunology, and disease pathogenesis including the likelihood of extraintestinal and systemic infections. The advent of new diagnostic tests that detect all of the currently identify human astrovirus strains may prove that these viruses are more prevalent in populations than currently realized.This book will provide state-of-the-art information on our current understanding of astroviruses for researchers, medical and veterinary providers, and diagnosticians as prepared by the leaders in the respective fields. The goal is to bring the reader up to date on the state of knowledge on this constantly evolving and exciting field of virology.
- 2015 Wileyedited by William T. Jackson and Michele S. Swanson.Autophagy and immunity / Xu Liu and Daniel J. Klionsky -- Techniques for studying autophagy / Isei Tanida and Masato Koike -- Role of autophagy in DNA virus infections in vivo / Xionan Dong and Beth Levine -- Studying RNA viruses and autophagy in vivo / Mehrdad Alirezaei and J. Lindsay Whitton -- Autophagy and picornavirus infection / Tom Wileman, Zhigang Zhou, Matthew Whelband, Eleanor Cottam, Stephen Berryman, Terry Jackson, and Rebecca Roberts -- Flaviviruses and autophagy / Tristan X. Jordan and Glenn Randall -- Autophagy : a home remodeler for Hepatitis C virus / Marine L.B. Hillaire, Elodie Decembre, and Marlene Dreux -- Modulating autophagy to cure Human Immunodeficiency Virus type-1 / Stephen A. Spector and Grant R. Campbell -- Autophagy in the infected cell : insights from pathogenic bacteria / Andrea Sirianni and Serge Mostowy -- Rab proteins in autophagy: streptococcus model / Ichiro Nakagawa -- Helicobacter pylori infection control by autophagy / Laura K. Greenfield, Frances Dang, and Nicola L. Jones -- Interactions between salmonella and the autophagy system / Teresa L.M. Thurston and David W. Holden -- Host factors that recruit autophagy as defense against toxoplasma gondii / Carlos S. Subauste -- Mycobacterium tuberculosis and the autophagic pathway / Gabriela María Recalde and María Isabel Colombo -- Autophagy enhances the efficacy of BCG vaccine / Arshad Khan, Christopher R. Singh, Emily Soudani, Pearl Bakhru, Sankaralingam Saikolappan, Jeffrey D. Cirillo, N. Tony Eissa, Subramanian Dhandayuthapani, and Chinnaswamy Jagannath -- Autophagy's contribution to innate and adaptive immunity : an overview / Christina Bell, Michel Desjardins, Pierre Thibault, and Kerstin Radtke -- Autophagy in immune responses to viruses / Christophe Viret and Mathias Faure -- Processing and MHC presentation of antigens after autophagy-assisted endocytosis, exocytosis and cytoplasm degradation / Christian Münz.
- 2008 Kargervolume editors, H.-D. Klenk, M.N. Matrosovich, J. Stech.Epidemiology of avian influenza / Osterhaus, A.D.M.E., Munster, V.J., Fouchier, R.A.M. -- H5N1 in Asia / Yen, H.-L. ... [et al.] -- Epidemiology and control of H5N1 avian influenza in China / Chen, H., Bu, Z., Wang, J. -- Avian influenza in Northern Eurasia / Lvov, D.K., Kaverin, N.V. -- Avian influenza in Italy, 1997-2006 / Capua, I. ... [et al.] -- Avian influenza outbreaks in Germany : development of new avian vaccines / Werner, O. ... [et al.] -- The role of pigs in interspecies transmission / Brown, I.H. -- History of research on avian influenza / Scholtissek, C. -- Reverse genetics of influenza viruses : applications in research and vaccine design / Neumann, G., Horimoto, T., Kawaoka, Y. -- Receptor specificity of influenza viruses and its alteration during interspecies transmission / Matrosovich, M.N., Gambaryan, A.S., Klenk, H.-K. -- Cleavage activation of the influenza virus hemagglutinin and its role in pathogenesis / Garten, W., Klenk, H.-D. -- Structure and function of the influenza A virus ribonucleoprotein : transcription and replication / Ortín, J. -- Influenza A virus polymerase : a determinant of host range and pathogenicity / Stech, J. -- Influenza A virus virulence and innate immunity : recent insights from new mouse models / Haller, O., Kochs, G., Staeheli, P. -- Signaling to life and death : influenza viruses and intracellular signal transduction cascades / Ludwig, S. ... [et al.] -- Cytokines in the pathogenesis of highly virulent influenza viruses in humans / Van Reeth, K. -- Antivirals and resistance / Hay, A.J., Collins, P.J., Russell, R.J. -- The 1918 influenza pandemic : lessons from the past raise questions for the future / Steel, J., Palese, P.
- 2009 SpringerIlaria Capua, Dennis J. Alexander, editors.
- 2008 Springer ProtocolsErica Spackman, editor.A brief introduction to the avian influenza virus / Erica Spackman -- Avian influenza virus sample types, collection, and handling / Mary Lea Killian -- Avian influenza virus RNA extraction from tissue and swab material / Erica Spackman and David L. Suarez -- Type A influenza virus detection and quantitation by real-time RT-PCR / Erica Spackman and David L. Suarez -- Detection and identification of the H5 hemagglutinin subtype by real-time RT-PCR -- Avian influenza virus isolation and propagation in chicken eggs / Peter R. Woolcock -- Hemagglutination-inhibition test for avian influenza virus subtype identification and the detection and quantitation of serum antibodies to the avian influenza virus / Janice C. Pedersen -- Neuraminidase-inhibition assay for the identification of influenza A virus neuraminidase subtype or neuraminidase antibody specificity / Janice C. Pedersen -- Immunohistochemical staining for the detection of the avian influenza virus in tissues / Mary J. Pantin-Jackwood -- Wild bird surveillance for the avian influenza virus / Justin D. Brown and David E. Stallknecht -- Reverse genetics of the avian influenza virus / Chang-Won Lee and David L. Suarez -- Evaluating the cell-mediated immune response of avian species to avian influenza viruses / Darrell R. Kapczynski -- Measurement of avian cytokines with real-time RT-PCR following infection with the avian influenza virus / Darrell R. Kapczynski and Michael H. Kogut.
- 2005 CRCnetBASEedited by Elizabeth Kutter, Alexander Sulakvelidze.
- 2007 Springer Protocolsedited by David W. Murhammer.
- 2008Edward K. Wagner, Martinez J. Hewlett, David C. Bloom, David Camerini.Introduction : the impact of viruses on our view of life -- An outline of virus replication and viral pathogenesis -- Virus disease in populations and individual animals -- Patterns of some viral diseases of humans -- Virus structure and classification -- The beginning and end of the virus replication cycle -- Host immune response to viral infection : the nature of the vertebrate immune response -- Strategies to protect against and combat viral infection -- Visualization and enumeration of virus particles -- Replicating and measuring biological activity of viruses -- Physical and chemical manipulation of the structural components of viruses -- Characterization of viral products expressed in the infected cell -- Viruses use cellular processes to express their genetic information -- Replication of positive-sense RNA viruses -- Replication strategies of RNA viruses requiring RNA-directed mRNA transcription as the first step in viral gene expression -- Replication strategies of small and medium-sized DNA viruses -- Replication of some nuclear-replicating eukaryotic DNA viruses with large genomes -- Replication of cytoplasmic DNA viruses and "large" bacteriophages -- Retroviruses : converting RNA to DNA -- HIV and related lentiviruses -- Hepadnaviruses : variations on the retrovirus theme -- The molecular genetics of viruses -- Molecular pathogenesis -- Viral bioinformatics and beyond -- Viruses and the future : problems and promises.
- Biophysical analysis of bacterial and viral systems : a shock tube study of bio-aerosols and a correlated AFM/NanoSIMS investigation of vaccinia virus2013Sean Damien Gates.The work presented herein is concerned with the development of biophysical methodology designed to address pertinent questions regarding the behavior and structure of select pathogenic agents. Two distinct studies are documented: a shock tube analysis of endospore-laden bio-aerosols and a correlated AFM/NanoSIMS study of the structure of vaccinia virus. An experimental method was formulated to analyze the biological and morphological response of endospores to gas dynamic shock waves. A novel laser diagnostic system was implemented to provide time resolved data concerning the structural decomposition of endospores in shock-heated flows. In addition, an ex situ methodology combining viability analysis, flow cytometry and scanning electron microscopy was employed to both assess the biological response of the endospore to the shock event, as well as to provide complementary data regarding the structural state of the treated endospore. This methodology was implemented to model the shock wave induced response of a variety of Bacillus endospores. The results are subsequently synthesized into a theoretical framework to be employed in modeling the interaction of endospore-laden bio-aerosols with blast waves. An analytical method combining atomic force microscopy (AFM) and nanometer-scale secondary ion mass spectrometry (NanoSIMS) was developed to examine the spatial localization and depth distribution of specific biological elements in viral systems. This methodology was implemented to analyze the distribution of 13C labeled fatty acids as well as 15N labeled thymidine in individual nanometer sized vaccinia viral particles. Based upon the 13C and 15N signals, three-dimensional depth-resolved data regarding the architecture and localization of the virion lipid membrane and the nucleoprotein complex was generated. In addition, this methodology was employed to provide direct correlation of architectural and chemical data for isolated sub-viral structures. The technique and results presented herein represent a novel tool for the structural and chemical study of both intact viral particles as well as specifically targeted sub-viral elements.
- 2012 SpringerErle S. Robertson, editor.Peyton Rous: A Centennial Tribute to the Founding Father of Cancer Virology -- Viruses and Cancer: A Historical Perspective - HBV and Prevention of a Cancer -- Virus-Mediated Cell Proliferation -- Viral-Encoded Genes and Cancer -- Oncogenic Viruses and Cancer Transmission -- DNA Viruses and Cancer: Taking a Broader Look -- Herpesviruses and Cancer -- Lymphocryptoviruses: EBV and Its Role in Human Cancer -- Nonhuman Primate Gamma-herpesviruses and Their Role in Cancer -- Rhadinoviruses: KSHV and Associated Malignancies -- Retroperitoneal Fibromatosis Herpesvirus and Kaposi's Sarcoma-Like Tumors in Macaques -- Murine Gammaherpesvirus-Associated Tumorigenesis -- Marek's Disease Virus-Induced T-Cell Lymphomas -- Polyomaviruses and Cancer -- Polyomavirus SV40: Model Infectious Agent of Cancer -- BK Polyomavirus and Transformation -- Polyomavirus JC and Human Cancer: Possible Role of Stem Cells in Pathogenesis -- Merkel Cell Polyomavirus -- Human Papillomaviruses and Cancer -- Tumorigenesis by Adenovirus Type 12 E1A -- Overview of Hepatitis Viruses and Cancer -- Hepadnaviruses and Hepatocellular Carcinoma -- Hepatitis C Virus and Hepatocellular Carcinoma -- Human and Animal Retroviruses: HIV-1 Infection Is a Risk Factor for Malignancy -- HTLV-1 and Oncogenesis -- Human T-Cell Leukemia Virus Type 2 (HTLV-2) Biology and Pathogenesis -- Mechanisms of Oncogenesis by Avian and Murine Retroviruses -- Rous Sarcoma Virus: Contributions of a Chicken Virus to Tumor Biology, Human Cancer Therapeutics, and Retrovirology -- Mouse Mammary Tumor Virus and Cancer -- Jaagsiekte Sheep Retrovirus and Lung Cancer -- Small RNAs and Their Role in Herpesvirus-Mediated Cancers -- Viral Malignancies in HIV-Associated Immune Deficiency.
- 2014 CRCnetBASEedited by Satya Prakash Gupta."Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), Human papilloma virus (HPV), Human herpes virus 8 (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV), Human immunodeficiency virus (HIV/AIDS), Oncolytic viruses. This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies"--Provided by publisher.
- 2010 SpringerJohn E. Johnson, editor.Preface / John E. Johnson, Peter K. Vogt -- Flock House Virus: A model system for understanding non-enveloped virus entry and membrane penetration / Amy Odegard, Manidipa Banerjee and John. E. Johnson -- The calciviruses / Umesh Katpally and Thomas J. Smith -- Picornaviruses / Tobias J. Tuthill ... [et al.] -- From touchdown to transcription: The reovirus cell entry pathway / Pranav Danthi ... [et al.] -- Rotavirus cell entry / Matthew Baker and B.V. Venkataram Prasad -- Structures and functions of parvovirus capsids and the process of cell infection / Colin R. Parrish -- Cellular entry of polyomaviruses / Billy Tsai and Mengding Qian -- Adenovirus / Jason G. Smith ... [et al.].Also available: Print – 2010
- Challenge of highly pathogenic microorganisms : mechanisms of virulence and novel medical countermeasures2010 SpringerAvigdor Schafferman, Arie Ordentlich, Baruch Velan, editors.The Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics / Arthur M. Friedlander -- Proteomic Studies of Bacillus anthracis Reveal In Vitro CO2-Modulation and Expression During Infection of Extracellular Proteases / Theodor Chitlaru, Orit Gat, Galia Zaide, Haim Grosfeld and Izhak Inbar, et al. -- Dynamics of Bacillus anthracis Infection and Control Mechanisms / Pierre L. Goossens, Ian J. Glomski, Lhousseine Touqui and Michèle Mock -- Survival and Trafficking of Yersinia pestis in Non-acidified Phagosomes in Murine Macrophages / James B. Bliska -- The Inverse Relationship Between Cytotoxicity of Y. pestis and Its Virulence / Emanuelle Mamroud, Avital Tidhar, Yinon Levy, Erez Bar-Haim and Gideon Halperin, et al. -- The NlpD Lipoprotein of Yersinia pestis is Essential for Cell Separation and Virulence / Avital Tidhar, Yehuda Flashner, Sara Cohen, Yinon Levy and Ayelet Zauberman, et al. -- Dissection of the Functions of the IglC Protein of Francisella tularensis / Jeanette E. Bröms, Moa Lavander and Anders Sjöstedt -- Yersinia pestis Lipopolysaccharide in Host-Pathogen Interactions / Andrey P. Anisimov, Svetlana V. Dentovskaya, Anna N. Kondakova, Buko Lindner and Rima Z. Shaikhutdinova, et al. -- The Interactions Between Pathogens and Dendritic Cells: From Paralysis of Cells to Their Recruitment for Bacterial Colonization / Baruch Velan, Erez Bar-Haim, Gal Markel, Hila Cohen and Ayelet Zauberman, et al. -- Comparative Approaches to Identify Host Factors Specifically Targeted by Yersinia pestis During the Infectious Process / Françoise Guinet, Patrick Avé, Louis Jones, Michel Huerre and Elisabeth Carniel -- Poxvirus Entry into Host Cells / Bernard Moss, Zain Bengali, Himani Bisht, Jason P. Laliberte and P.S. Satheskumar -- Role of A33R Amino-Acid 118L in the Interactions of Vaccinia Virus with the Host / Nir Paran, Shlomo Lustig, Anat Zvi, Tomer Israely and Sharon Melamed, et al. -- Inhibitors of Innate Immunity from Vaccinia Virus / Geoffrey L. Smith -- Brucella Species Synchronize Their Life Cycle to the Gestation Cycle of Their Ruminant Hosts / Svetlana Bardenstein and Menachem Banai -- MMP-9 as a Marker for Vaccinia Virus Related Encephalitis / Tomer Israely, Sharon Melamed, Noam Erez, Boaz Politi and Udy Olshevsky, et al. -- Epidemic Cowpox Virus Infections in Germany / Andreas Kurth and Andreas Nitsche -- The Two Partner Secretion Transporters of Yersinia pestis: Cloning, Immunogenicity and In Vivo Expression Following Airway Infection / Yinon Levy, Anat Zvi, Haim Grosfeld, Avital Tidhar and David Gur, et al. -- Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX) / Adi Beth-Din, Ofir Israeli, Ohad Shifman, Dana Stein and Einat Ben-Arie, et al. -- Subtyping Biothreat Bacterial Pathogens / Paul Keim and Talima Pearson -- A Rapid Method for Bacillus anthracis Genotyping / Haim Levy, Morly Fisher, Naomi Ariel, Shay Weiss and Anat Zvi, et al. -- Tularemia - A Disease with an Uncertain Impact on Public Health / Roland Grunow, Daniela Jacob, Andrea Kühn and Herbert Nattermann -- Consequences of Antibiotic Treatment of Francisella tularensis Airways Infections / Erez Bar-Haim, Hila Cohen, Raphael Ber, Ofer Cohen and Avigdor Shafferman -- Novel Live Vaccine Candidates Against Airborne Francisella tularensis / Wayne Conlan and Anders Sjöstedt -- Effect of Disruption of mglA on the Virulence and Immunogenicity of the Francisella tularensis Live Vaccine Strain (LVS) / Ofer Cohen, Galia Zaide, Erez Bar-Haim, Itai Mendelson and Orit Gat, et al. -- Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates / Anat Zvi, Naomi Ariel and Avigdor Shafferman -- Modified Vaccinia Virus Ankara (MVA) based Vaccines - Immunostimulatory and Protective Capacity / Michael H. Lehmann, Melanie Kremer, Yasemin Suezer and Gerd Sutter -- Therapeutic Potential of Vaccinia Hyper Immune Sera in Mouse Models of Lethal Orthopoxviruses Infection / Sharon Melamed, Nir Paran, Tomer Israely, Noam Erez and Shaul Reuveny, et al. -- A Live Plaque Vaccine Candidate with Improved Safety and Immunogenecity / V.A. Feodorova, L.N. Pan'kina, E.P. Savostina, O.S. Kuznetsov and N.P. Konnov, et al. -- Protection Against Plague Afforded by Treatment with Polyclonal αLcrV and αF1 Antibodies / Yinon Levy, Yehuda Flashner, Ayelet Zauberman, Avital Tidhar and Moshe Aftalion, et al. -- Combination of Anthrax-Toxin Neutralizing Antibodies: Analysis of Synergism/Antagonism Effect / Ohad Mazor, Einat Ben-Arie, Adva Mechaly, Ronit Rosenfeld and Hadar Marcus, et al. -- The Efficacy of Antibiotic Treatment to Cure Guinea Pigs Intranasally Infected with Bacillus anthracis Spores / Zeev Altboum, Haim Levy, Shay Weiss, Avi Pass and Nili Rothschild, et al. -- Reverse Vaccinology in Bacillus anthracis / Avigdor Shafferman, Orit Gat, Naomi Ariel, Theodor Chitlaru and Haim Grosfeld, et al.
- 2013 SpringerLarry J. Anderson, Barney S. Graham, editors.Part I. Virology, pathogenesis, and clinical and epidemiological features of disease -- Part II. Host response to infection and genetics of disease -- Part III. Vaccine platforms and treatment options -- Part IV. Animal and tissue culture models of infection -- Part V. Conclusions -- Index.
- 2006 SpringerT.E. Lane, ed.Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system / T.E. Lane, J.L. Hardison, and K.B. Walsh -- Cytokine and chemokine networks : pathways to antiviral defense / T.P. Salazar-Mather and K.L. Hokeness -- Herpes simplex virus and the chemokines that mediate the inflammation / D.J.J. Carr and L. Tomanek -- Influence of proinflammatory cytokines and chemokines on the neuropathogenesis of oncornavirus and immunosuppressive lentivirus infections / K.E. Peterson and B. Chesebro -- HIV-1 coreceptors and their inhibitors / N. Ray and R.W. Doms -- A viral conspiracy : hijacking the chemokine system through virally encoded pirated chemokine receptors / H.F. Vischer, C. Vink, and M.J. Smit.
- 2012 SpringerMitchell L. Shiffman, editor.Part I. Natural history of chronic HCV -- 1. Epidemiology of chronic HCV / Gary L. Davis -- 2. Acute HCV / Katja Deterding, Heiner Wedemeyer, and Michael P. Manns -- 3. Assessing the progression of chronic HCV to cirrhosis / Gonzolo Crespo, Stella M. Martinez, and Xavier Forns -- 4. Chronic HCV and steatosis / Dawn McDowell Torres and Stephen A. Harrison -- 5. Chronic HCV and hepatocellular carcinoma / Morris Sherman -- 6. Extrahepatic manifestations of chronic HCV / Vincenza Calvaruso and Antonio Craxì -- 7. Chronic HCV and HIV coinfection / Patrick Ingiliz, Maud Lemoine, and Yves Benhamou -- 8. Chronic HCV in patients with renal disease / Paul Martin and Fabrizio Fabrizi -- 9. Does treatment alter the natural history of chronic HCV? / Fasiha Kanwal and Bruce R. Bacon -- Part II. Treatment of chronic HCV with interferon-based therapy -- 10. Treatment with interferon and ribavirin / William Kemp and Stuart K. Roberts -- 11. Immune modulators and other agents / Edgar D. Charles and Ira M. Jacobson -- 12. Measuring HCV RNA and assessing virologic response / Jean-Michel Pawlotsky -- 13. Response-guided therapy / Mitchell L. Shiffman -- 14. Managing the side effects of therapy / Curtis Cooper -- 15. Genetics of virologic response / Alison B. Jazwinski and Andrew J. Muir -- 16. Maintenance therapy with peginterferon / Raza Malik and Nezam H. Afdhal -- Part III. Anti-viral therapy for chronic HCV -- 17. Antiviral targets in HCV / B. Kronenberger and S. Zeuzem -- 18. Mutations and the development of anti-viral resistance / Anna Maria Geretti and Geoff Dusheiko -- 19. Peginterferon, ribavirin and anti-viral triple therapy / Patrick Marcellin, Nathalie Boyer, and Tarik Asselah -- 20. Treating chronic HCV without interferon and/or ribavirin / Edward J. Gane -- 21. Maintenance therapy with oral antiviral agents / Andrew Aronsohn and Donald Jensen -- Part IV. Liver transplantation for chronic HCV -- 22. Natural history of chronic HCV after liver transplantation / Bart J. Veldt and Michael R. Charlton -- 23. Use of HCV-positive organs in patients with and without chronic HCV / Elizabeth C. Verna and Robert S. Brown Jr. -- 24. Treating HCV prior to liver transplantation / Alvaro Martinez-Camacho, Brett E. Fortune, and Gregory T. Everson -- 25. Treating HCV after liver transplantation / Michael Chang, Hubert Sung, and Sammy Saab.
- 2009 Am Soc Microbioleditors, Steven Specter, Richard L. Hodinka, Stephen A. Young, Danny L. Wiedbrauk.
- 2009 Am Soc Microbioleditors, Douglas D. Richman, Richard J. Whitley, Frederick G. Hayden.Introduction / Douglas D. Richman, Richard J. Whitley, and Frederick G. Hayden -- Section I: Viral syndromes and general principles -- Respiratory infections / John J. Treanor -- Viral central nervous system infections / Kevin A. Cassady and Richard J. Whitley -- Gastrointestinal syndromes / Manish Patel and Roger I. Glass -- Viral hepatitis / Andrew W. Tai and Jules L. Dienstag -- Infections in organ transplant recipients / John A. Zaia -- Viral myocarditis / Jeffrey A. Towbin -- Viral infections of the skin / Brenda L. Bartlett and Stephen K. Tyring -- Viral hemorrhagic fevers: a comparative appraisal / Mike Bray and Karl M. Johnson -- Viral disease of the eye / Garry Shuttleworth and David Easty -- Antiretroviral agents / Magdalena E. Sobieszczyk, Barbara S. Taylor, and Scott M. Hammer -- Antiherpesvirus, anti-hepatitis virus, and anti-respiratory virus agents / Michael T. Yin ... [et al.] -- Diagnosis of viral infections / Guy Boivin ... [et al.] -- Immune responses to viruses / Jonathan W. Yewdell, Theodore C. Pierson, and Jack R. Bennink -- Immunization against viral diseases / Julie E. Martin and Barney S. Graham -- Gene therapy and viruses / Donald B. Kohn ... [et al.] -- Chronic fatigue and postinfective fatigue syndromes / Andrew R. Lloyd, Ian Hickie, and Denis Wakefield -- Section II: The agents -- Part A: DNA viruses -- Poxviruses / R. Mark Buller and Frank Fenner -- Herpes simplex viruses / Richard J. Whitley and Bernard Roizman -- Cercopithecine herpesvirus 1 (B virus) / Richard J. Whitley -- Varicella-zoster virus / Anne A. Gershon and Saul J. Silverstein -- Cytomegalovirus / Paul David Griffiths, Vincent Clive Emery, and Richard Milne -- Human herpesvirus 6 and human herpesvirus 7 / Koichi Yamanishi and Yasuko Mori -- Epstein-Barr virus / Katherine Luzuriaga and John L. Sullivan -- Kaposi's sarcoma-associated herpesvirus / Patrick S. Moore and Yuan Chang -- Adenoviruses / Olli Ruuskanen ... [et al.] -- Polyomaviruses / John E. Greenlee and Frank J. O'Neill -- Papillomavirus / William Bonnez -- Human Parvoviruses / Larry J. Anderson and Dean D. Erdman -- TT virus / Peter Simmonds -- Hepatitis B virus / Alexander J. V. Thompson, Sally J. Bell, and Stephen A. Locarnini -- Part B: RNA viruses -- Human lymphotropic viruses: HTLV-1 and HTLV-2 / William A. Blattner and Manhattan E. Charurat -- Human immunodeficiency virus / John C. Guatelli ... [et al.] -- Colorado tick fever virus and other arthropod-borne Reoviridae / Steven Yukl and Joseph K. Wong -- Rotaviruses / Manuel A. Franco and Harry B. Greenberg -- Respiratory syncytial virus, human metapneumovirus, and parainfluenza viruses / John V. Williams, Pedro A. Piedra, and Janet A. Englund -- Measles virus / William J. Moss and Diane E. Griffin -- Mumps virus / John W. Gnann, Jr. -- Zoonotic paramyxoviruses / Paul A. Rota, Thomas G. Ksiazek, and William J. Bellini -- Rhabdoviruses / Thomas P. Bleck and Charles E. Rupprecht -- Filoviruses / Mike Bray -- Influenza virus / Frederick G. Hayden and Peter Palese -- Bunyaviridae: bunyaviruses, phleboviruses, nairoviruses, and hantaviruses / Gregory J. Mertz -- Arenaviruses / C. J. Peters -- Enteroviruses / José R. Romero -- Rhinovirus / Ronald B. Turner and Wai-Ming Lee -- Hepatitis A virus / Philip R. Spradling, Annette Martin, and Stephen M. Feinstone -- Human caliciviruses / Robert L. Atmar and Mary K. Estes -- Hepatitis E virus / David A. Anderson and Iswar L. Shrestha -- Astrovirus / Ernesto Méndez and Carlos F. Arias -- Coronaviruses / Kenneth McIntosh and J. S. M. Peiris -- Arthropod-borne flaviviruses / Lyle R. Petersen and Alan D. T. Barrett -- Hepatitis C virus / Yaron Rotman and T. Jake Liang -- Alphaviruses / David W. Smith, John S. Mackenzie, and Scott C. Weaver -- Rubella virus / David W. Kimberlin -- Part C: Subviral agents -- Hepatitis D virus / Antonina Smedile, Alessia Ciancio, and Mario Rizzetto -- Transmissible spongiform encephalopathies / Adriano Aguzzi.
- 2008 SpringerOlaf Weber, Ulrike Protzer, editors.
- 2007 ScienceDirecteditor: Isa K. Mushahwar.
- 2005 SpringerL. Enjuanes (ed.).Coronavirus genome structure and replication / D.A. Brian and R.S. Baric -- Coronavirus transcription : a perspective / S.G. Sawicki and D.L. Sawicki -- The coronavirus replicase / J. Ziebuhr -- Viral and cellular proteins involved in coronavirus replication / S.T. Shi and M.M.C. Lai -- Coronavirus reverse genetics by targeted RNA recombination / P.S. Masters and P.J.M. Rottier -- Coronavirus reverse genetics and development of vectors for gene expression / L. Enjuanes ... [et al.] -- Reverse genetics of coronaviruses using vaccinia virus vectors / V. Thiel and S.G. Siddell -- Development of mouse hepatitis virus and SARS-CoV infectious cDNA constructs / R.S. Baric and A.C. Sims.
- 2015 Springer Protocolsedited by Helena Jane Maier, Erica Bickerton, Paul Britton.Coronaviruses : an overview of their replication and pathogenesis / Anthony R. Fehr and Stanley Perlman -- Identification of a novel coronavirus from Guinea Fowl using metagenomics / Mariette F. Ducatez and Jean-Luc Guérin -- Serological diagnosis of feline coronavirus infection by immunochromatographic test / Tomomi Takano and Tsutomu Hohdatsu -- Estimation of evolutionary dynamics and selection pressure in coronaviruses / Muhammad Munir and Martí Cortey -- Preparation of chicken tracheal organ cultures for virus isolation, propagation, and titration / Ruth M. Hennion -- Preparation of chicken kidney cell cultures for virus propagation / Ruth M. Hennion and Gillian Hill -- Isolation and propagation of coronaviruses in embryonated eggs / James S. Guy -- Characterization of human coronaviruses on well- differentiated human airway epithelial cell cultures / Hulda R. Jonsdottir and Ronald Dijkman -- Quantification of infectious bronchitis coronavirus by titration in vitro and in ovo / Joeri Kint, Helena Jane Maier, and Erik Jagt -- Purification of coronavirus virions for Cryo-EM and proteomic analysis / Stuart Dent and Benjamin W. Neuman -- Partial purification of IBV and subsequent isolation of viral RNA for next-generation sequencing / Sarah M. Keep, Erica Bickerton, and Paul Britton -- Transient dominant selection for the modification and generation of recombinant infectious bronchitis coronaviruses / Sarah M. Keep, Erica Bickerton, and Paul Britton -- Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes / Fernando Almazán ... [et al.] -- Protein histochemistry using coronaviral spike proteins : studying binding profiles and sialic acid requirements for attachment to tissues / Iresha N. Ambepitiya Wickramasinghe and M. Hélène Verheije -- Identification of protein receptors for coronaviruses by mass spectrometry / V. Stalin Raj ... [et al.] -- Single particle tracking assay to study coronavirus membrane fusion / Deirdre A. Costello and Susan Daniel -- Studying coronavirus-host protein interactions / Chee-Hing Yang ... [et al.] -- Field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions / Pierre- Olivier Vidalain ... [et al.] -- Investigation of the functional roles of host cell proteins involved in coronavirus infection using highly specific and scalable RNA interference (RNAi) approach / Jean Kaoru Millet and Béatrice Nal -- Transcriptome analysis of feline infectious peritonitis virus infection / Parvaneh Mehrbod ... [et al.] -- Quantification of interferon signaling in avian cells / Joeri Kint and Maria Forlenza -- Studying the dynamics of coronavirus replicative structures / Marne C. Hagemeijer and Cornelis A. M. de Haan -- Preparation of cultured cells using high-pressure freezing and freeze substitution for subsequent 2D or 3D visualization in the transmission electron microscope / Philippa C. Hawes.
- 2007 SpringerOnder Ergonul, Chris A. Whitehouse, editors.
- 2012 Springerby Marc E. Grossman, Lindy P. Fox, Carrie Kovarik, Misha Rosenbach.Subcutaneous and deep mycoses -- Hyalohyphomycosis -- Superficial mycoses -- Algae -- Mycobacteria -- Viruses -- Rickettsiae -- Crusted scabies -- Protozoa -- Helminth -- Spirochete -- Gram-Positive bacteria -- Gram-negative bacteria -- Viral related malignancies -- Clues to the diagnosis of skin lesions in the immunocompromised host -- Differential diagnoses.
- 2011 Springeredited by Mark W. Robinson, John P. Dalton."Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research"--Provided by publisher.Also available: Print – 2011
- 2014 Springer Protocolsedited by Radhakrishnan Padmanabhan, Subhash G. Vasudevan.Dengue Virus Growth, Purification and Fluorescent Labeling -- Isolation and Titration of Dengue Viruses by the Mosquito Inoculation Technique -- Measuring Antibody Neutralization of Dengue Virus (DENV) Using a Flow Cytometry-Based Technique -- Dengue Virus Purification and Sample Preparation for Cryo-Electron Microscopy -- Development of a Multiplex Bead-Based Assay to Monitor Dengue Virus Seroconversion -- Pseudo-Infectious Reporter Virus Particles for Measuring Antibody-Mediated Neutralization and Enhancement of Dengue Virus Infection -- Cell-Based Flavivirus Infection (CFI) Assay for the Evaluation of Dengue Antiviral Candidates Using High Content Imaging -- Development and Application of Dengue Virus Reverse Genetic Systems -- DENV4 Renilla Luciferase Reporter Replicons -- Targeted Mutagenesis of Dengue Virus Type 2 replicon RNA by Yeast in vivo Recombination -- Identification of Dengue-Specific Human Antibody Fragments Using Phage Display -- Next Generation Whole Genome Sequencing of Dengue Virus -- MPGAfold in Dengue Secondary Structure Prediction -- Insights into Secondary and Tertiary Interactions of Dengue Virus RNA by SHAPE -- Use of Small Angle X-Ray Scattering to Investigate the Structure and Function of Dengue Virus NS3 and NS5 -- Identification of Dengue RNA Binding Proteins Using RNA Chromatography and Quantitative Mass Spectrometry -- Analysis of Affinity of Dengue Virus Protein Interaction Using BIAcore -- Functional Genomics Approach for the Identification of Human Host Factors Supporting Dengue Viral Propagation -- Investigating Dengue Virus Non-Structural Protein 5 (NS5) Nuclear Import -- Small Molecule Inhibitor Discovery for Dengue Virus Protease Using High Throughput Screening -- Construction of Dengue Virus Protease Expression Plasmid and in vitro Protease Assay for Screening Antiviral Inhibitors -- Construction of Plasmid, Bacterial Expression, Purification, and Assay of Dengue Virus Type 2 NS5 Methyltransferase -- Animal Models in Dengue -- Evaluation of Dengue Antiviral Candidates In Vivo in Mouse Model.
- 2010 SpringerAlan L. Rothman, editor.Prospective cohort studies of dengue viral transmission and severity of disease / Timothy P. Endy, In-Kyu Yoon, Mammen P. Mammen -- Control of dengue virus translation and replication / Suman M. Paranjape, Eva Harris -- Subversion of interferon by dengue virus / Jorge L. Munoz-Jordan -- Dengue virus virulence and transmission determinants / R. Rico-Hesse -- Systemic vascular leakage associated with dengue infections - the clinical perspective / Dinh D. Trung, Bridget Wills -- Markers of dengue disease severity / Anon Srikiatkhachorn, Sharone Green -- Cellular immunology of sequential dengue virus infection and its role in disease pathogenesis / Alan L. Rothman -- HLA and other gene associations with dengue disease severity / H.A.F. Stephens -- Vector dynamics and transmission of dengue virus: implications for dengue surveillance and prevention strategies / Thomas W. Scott, Amy C. Morrison -- Dengue vaccine candidates in development / Anna P. Durbin, Stephen S. Whitehead -- Targeted mutagenesis as a rational approach to dengue virus vaccine development / Joseph E. Blaney Jr., Anna Pl Durbin, Brian R. Murphy, Stephen S. Whitehead.Also available: Print – 2010
- 2013 SpringerKeith Taylor, Heikki Hyöty, Antonio Toniolo, Arie J. Zuckerman, editors.Diabetes, in all of its forms, now constitutes a growing health concern, affecting all segments of the world's population. There is great interest in the factors which influence its etiology and progression. Among these, a number of viruses feature prominently. Hindered by technological limitations, research into this relationship has hitherto been scarce. Recent advances, however, have opened up the field and there is a burgeoning body of literature on the subject. Unfortunately, this literature has been diffuse and often difficult to access.For the first time, this book compiles the views of many of the world's experts in the field. It addresses questions, ranging from how viruses may destroy or modify the function of pancreatic islets; to which viruses are the most likely culprits; to whether vaccines or etiologic therapies might be used to prevent virus-induced diabetes. Diabetes and Viruses is the first comprehensive volume on an important and expanding field of research that is of interest to clinicians, healthcare managers, epidemiologists, veterinarians, and basic scientists.
- 2009Brian W.J. Mahy.
- 2009 SpringerBlossom Damania, James M. Pipas, editors.Polyomavirus life cycle / Ellen Fanning, Xiaorong Zhao, and Xiaohua Jiang -- Transformation by polyomaviruses / Dweepanita Das and Michael J. Imperiale -- Polyomaviruses and disease / Jaime M. Kean and Robert L. Garcea -- The life cycle of human papillomaviruses / Cary A. Moody and Laimonis A. Laimins -- Papillomavirus transformation / Kimberly Johung and Daniel DiMaio -- Papillomaviruses : biology, diversity, and pathogenesis / Hans-Ulrich Bernard -- Adenovirus transformation / Patrick Hearing -- Overview of the large DNA tumor viruses / Subhash C. Verma ... [et al.] -- Epidemiology of EBV infection / Rosemary Rochford -- EBV diseases / Joseph S. Pagano -- The Epstein-Barr virus genome / Jeffery T. Sample ... [et al.] -- Epstein-Barr virus transforming proteins : biologic properties and contribution to oncogenesis / Nancy Raab-Traub -- The Epstein-Barr virus lytic life cycle / Sankar Swaminathan and Shannon Kenney -- Epstein-Barr virus latent infection nuclear proteins : genome maintenance and regulation of lymphocyte cell growth and survival / Eric Johannsen ... [et al.] -- Epstein-Barr virus entry / Richard Longnecker, Lindsey Hutt-Fletcher, and Theodore Jardetzky -- EBV immunotherapy / Leslie E. Huye and Cliona M. Rooney -- KSHV epidemiology and subtype evolution / Gary S. Hayward and Denise Whitby -- Introduction to diseases associated with Kaposi's sarcoma-associated herpesvirus / Patrick S. Moore and Yuan Chang -- Organization and expression of the Kaposi's sarcoma-associated herpesvirus genome / Yan Yuan and Rolf Renne -- KSHV latent genes and their regulation / Dirk P. Dittmer -- Regulation of expression, mode of action and downstream targets of ORF50 protein in KSHV lytic cycle activation / Pey-Jium Chang, Jianjiang Ye, and George Miller -- HHV-8/KSHV proteins involved in signaling and transformation / Silke Hartmann, Thomas F. Schulz, and John Nicholas -- KSHV entry and infection of target cells / Bala Chandran and Neelam Sharma-Walia -- KSHV immune evasion / Chengyu Liang ... [et al.] -- Non-coding regulatory RNAs of the DNA tumor viruses / Christopher S. Sullivan and Bryan R. Cullen -- AIDS and associated malignancies / William J. Harrington, Charles Wood, and C. Wood -- Primate models for gammaherpesvirus-associated malignancies / Ilhem Messaoudi, Blossom Damania, and Scott W. Wong -- Murine gammaherpesvirus 68 infection of mice : a small animal model for characterizing basic aspects of gammaherpesvirus pathogenesis / James Craig Forrest, Laurie T. Krug, and Samuel H. Speck.
- 2013 SpringerLori Frappier.Introduction -- Roles of EBNA1 at EBV Episomes -- EBNA1-DNA Interactions -- EBNA1 Contributions to EBV-Associated Tumours -- Cellular Effects of EBNA1 -- Conclusion.
- 2015 UNICEF
- 2015The Overview of Needs and Requirements covers the costs of the Ebola response and preparedness activities. The needs and requirements are based on the latest information available from each of the most affected countries. The national plans and budgets comprise the framework and the Overview of Needs and Requirements defines the contributions planed by the UN system as well as the major international civil society organizations.
- 2013 WileyPrakash S. Bisen and Ruchika Raghuvanshi.A global perspective on the management and prevention of emerging and re-emerging diseases Emerging infectious diseases are newly identified or otherwise previously unknown infections that cause public health challenges. Re-emerging infectious diseases are due to both the reappearance of and an increase in the number of infections from a disease that is known, but which had formerly caused so few infections that it was no longer considered a public health problem. The factors that cause the emergence or re-emergence of a disease are diverse. This book takes a look at the worl
- 2007 ScienceDirecteditor: Edward Tabor.
- 2014 SpringerIan MacKay, Noel R. Rose, editors-in-chief ; Betty Diamond, Anne Davidson, editors.
- 2015 Springerv. 2 SpringerChristian Münz, editor.
- 2007 Ovideditors-in-chief, David M. Knipe, Peter M. Howley ; associate editors, Diane E. Griffin ... [et al.].Also available: Print – v. 1-2., 2007
- 2013 Ovideditors-in-chief, David M. Knipe, Peter M. Howley ; associate editors, Jeffrey I. Cohen, Diane E. Griffin, Robert A. Lamb, Malcolm A. Martin, Vincent R. Racaniello, Bernard Roizman.Virology: from contagium fluidum to virome -- Principles of virology -- Principles of virus structure -- Virus entry and uncoating -- Viral replication strategies -- Virus assembly -- Viruses, cell transformation, and cancer -- Innate responses to viral infections -- Adaptive immune response to viral infections -- Pathogenesis of viral infection -- Virus evolution -- Epidemiology -- Antiviral agents -- Immunization against viral diseases -- Diagnostic virology -- Picornaviridae: the viruses and their replication -- Enteroviruses: polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses -- Rhinoviruses -- Hepatitis A virus -- Caliciviridae: the noroviruses -- Astroviruses -- Togaviridae -- Alphaviruses -- Rubella virus -- Flaviviridae -- Flaviviruses -- Hepatitis C virus -- Coronaviridae -- Arteriviruses -- Mononegavirales -- Rhabdoviridae -- Filoviridae: marbug and ebola viruses -- Paramyxoviridae -- Parainfluenza viruses -- Mumps virus -- Measles virus -- Henipaviruses -- Respiratory syncytial virus and metapneumovirus -- Bornaviridae -- Orthomyxoviridae -- Orthomyxoviruses -- Bunyaviridae -- Arenaviridae -- Orthoreoviruses -- Rotaviruses -- Orbiviruses -- Retroviridae -- Human t-cell leukemia virus types 1 and 2 -- Human immunodeficiency viruses: replication -- HIV-1: pathogenesis, clinical manifestations, and treatment -- Nonhuman lentiviruses -- Foamy viruses -- Polyomaviruses -- Papillomaviruses -- Adenoviridae -- Adenoviruses -- Parvoviridae -- Circoviridae -- Herpesviridae -- Herpes simplex viruses -- Epstein-Barr virus -- Cytomegaloviruses -- Varicella-Zoster virus -- Human herpesviruses 6 and 7 -- Kaposi's A. sarcoma-associated herpesvirus -- Poxiviridae -- Poxviruses -- Hepadnaviruses -- Hepatitis D (delta) virus -- Hepatitis E virus -- Mimivirus, other viruses infecting phagocytic protists, and their virophages -- Plants viruses -- Insect viruses -- Viruses and prions of yeasts, fungi, and unicellular eukaryotes -- Bacteriophages -- Prions.
- 2008 SpringerJens Kuhn.Introduction -- History of filoviral diseases outbreaks -- Clinical presentation of filoviral disease -- Filoviral disease pathology -- Geographic distribution of filoviruses : serological surveys -- Ecology of filoviruses : search for reservoirs -- Cultivation of filoviruses -- Molecular characteristics of filoviruses -- Laboratory diagnosis of filoviral disease -- Outbreak containment -- Inactivation of filoviruses and disinfection protocols -- Vaccine development -- Treatment of filoviral disease
- Fomites in infectious disease transmission : a modeling, laboratory, and field study on microbial transfer between skin and surfaces2010Timothy Ryan Julian.This dissertation examines the factors that influence fomite-mediated (e.g., indirect contact) transmission of viral gastrointestinal and respiratory illness. Specifically, the dissertation investigates virus transfer between surfaces and virus recovery from surfaces, models human-fomites interactions to estimate exposure and infection risk, and elucidates causal links between microbial contamination and illness in child care centers. Indirect contact transmission refers to person-to-person transmission of disease via an intermediate fomite (e.g., inanimate object acting as a carrier of infectious disease). The role of indirect contact in disease spread is poorly understood in part because the transmission route of viral pathogens is often difficult to determine. Transmission of respiratory and gastrointestinal viruses can occur through multiple routes (e.g., direct contact, indirect contact, airborne, and common vehicle), and the relative contribution of each route to total disease burden is unclear. The first study in this dissertation examines virus transfer between skin and surfaces, a necessary step in fomite-mediated transmission of viral disease. In the study, transfer of virus between fingerpads and fomites is explored in a laboratory setting. Bacteriophage (fr, MS2, and PHIX174) are used as proxies for pathogenic virus, and over 650 unique transfer events are collected from 20 different volunteers. The study concludes that approximately one quarter (23%) of recoverable virus is readily transferred from a contaminated surface (e.g., a fomite) to an uncontaminated surface (e.g., a finger) on contact. Using the large data set, the direction of transfer (from fingerpads-to-fomite or fomite-to-fingerpad) and virus species are demonstrated to both significantly influence the fraction of virus transferred by approximately 2-5%. To investigate the relative importance of factors contributing to fomite-mediated transmission, a child's risk of illness from exposure to a contaminated fomite is modeled. Specifically, the model estimates a child's exposure to rotavirus using a stochastic-mechanistic framework. Simulations of a child's contacts with the fomite include intermittent fomite-mouth, hand-mouth, and hand-fomite contacts based on activities of a typical child under six years of age. In addition to frequency of contact data, parameters estimated for use in the model include virus concentration on surface; virus inactivation rates on hands and the fomite; virus transfer between hands, fomite, and the child's mouth; and the surface area of objects and hands in contact. From the model, we conclude that a child's median ingested dose from interacting with a rotavirus-contaminated ball ranges from 2 to 1,000 virus over a period of one hour, with a median value of 42 virus. These results were heavily influenced by selected values of model parameters, most notably, the concentration of rotavirus on fomite, frequency of fomite-mouth contacts, frequency of hand-mouth contacts, and virus transferred from fomite to mouth. The model demonstrated that mouthing of fomite is the primary exposure route, with hand mouthing contributions accounting for less than one-fifth of the child's dose over the first 10 minutes of interaction. Based on the findings from the model that concentration of virus on a fomite influences a child's risk of illness, we investigate methods to recover virus from fomites. In a literature review and subsequent meta analysis, we demonstrate that the outcome currently used to describe virus contamination, positivity rate, is biased by the authors' selected sampling methods. We follow up, in the laboratory, with a comparison of the identified methods and demonstrate that polyester-tipped swabs prewetted in 1/4-strength Ringer's solution or saline solution is the most efficient sampling method for virus recovery tested. The recommended method is compatible with plaque assay and quantitative reverse-transcription polymerase chain reaction, two techniques used to quantify virus. The link between hand / fomite contamination and infection risk was explored in a field study at two child care centers over four months. Both respiratory and gastrointestinal disease incidence were tracked daily, while hand and environmental surface contamination were monitored weekly between February 2009 and June 2009. Microbial contamination was determined using quantitative densities of fecal indicator bacteria (e.g. Escherichia coli, enterococci, and fecal coliform) on hands and fomites as well as presence/absence of viral pathogens (e.g. enterovirus and norovirus). Health was monitored daily by childcare staff, who tracked absences, illness-related absences, and symptomatic respiratory and gastrointestinal illness. The resultant data suggests that increases in microbial contamination led to increases in symptomatic respiratory illness four to six days later, in agreement with typical incubation periods for respiratory illness. Similarly, respiratory illness led to increases in microbial contamination on hands during presentation of symptoms, and on fomites in the following three days.
- 2005 SpringerB.W.J. Mahy (ed.)
- 2012 SpringerAnna Kuchment.1. Helpful Little Bodies -- 2. Inside Stalin's Empire -- 3. The Fading of Phage Therapy -- 4. Naked Genes -- 5. 'They're Not a Panacea:' Phage Therapy in the Soviet Union and Georgia -- 6. In Poland: Phages for Diabetes? -- 7. The Renaissance of Phage Therapy -- 8. The Startups -- 9. Four Companies, Four Strategies -- 10. Cows and Chickens -- 11. Approval, At Last -- 12. In Treatment.
- 2013 SpringerPeter Zuber.This SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence. The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.
- 2015 ScienceDirectPatrick Arbuthnot, Wits and South African Medical Research Council, Antiviral Gene Therapy Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, South Africa.Essentials of viruses and their suitability for treatment ssing gene therapy -- Harnessing RNAi to silence viral gene expression -- Engineering sequence-specific DNA binding proteins for antiviral gene editing -- Viral vectors for delivery of antiviral sequences -- Delivery of antiviral nucleic acids with nonviral vectors -- Gene therapy for chronic hepatitis B virus infection -- Gene therapy for hepatitis C virus infection -- Gene therapy for HIV-1 infection -- Gene therapy for respiratory viral infections -- Gene therapy for infection with hemorrhagic fever viruses -- Gene transfer for prophylaxis and therapy of viral infections -- Antiviral gene therapy : summary and perspectives.
- 2010David William Hutton.Hepatitis B (HBV) is a vaccine-preventable viral disease that, if untreated, can lead to death from liver disease in 25 percent of patients. Infection with HBV is a major global public health problem, particularly in Asian populations. In an era of limited healthcare budgets, mathematical models can be useful tools to identify cost-effective programs and to support policymakers in making informed decisions. This dissertation describes research on public health policies related to screening, vaccination, and treatment for HBV. It also describe contributions to the theoretical literature on when to stop catch-up vaccination for chronic infectious diseases. In the United States as many as 10% of Asian and Pacific Islander adults are chronically infected with HBV, and up to two thirds are unaware that they are infected. Using Markov models of infection, treatment and disease, I find that screening programs for HBV among Asian and Pacific Islander adults are likely to be cost effective and have clinically significant benefits from identifying chronically infected persons for medical management. Liver disease associated with childhood-acquired HBV is a leading cause of death among adults in China. Approximately 20% of children under age 5 years and 40% of children aged 5 to 19 years remain unprotected from HBV. Using a Markov model of infection and disease progression I find that HBV catch-up vaccination for children and adolescents in China would improve the health of the population and save costs over the long term. Although the 20th century has seen incredible development of safe and effective vaccines, many people remain susceptible to vaccine-preventable diseases. "Catch-up vaccination" for age groups beyond infancy can be an attractive and effective means of immunizing people who were missed earlier. However, as vaccination rates increase, catch-up vaccination may become less attractive. This chapter addresses the question of when to discontinue catch-up vaccination programs as immunization rates increase. I use a cost-effectiveness framework: I consider the cost per quality-adjusted life year gained of catch-up vaccination efforts, as a function of immunization rates over time and consequent disease prevalence and incidence. I illustrate the results with the example of HBV catch-up vaccination in China. I contrast results from a dynamic modeling approach with an approach that ignores the impact of vaccination on disease incidence.
- 2007 Springer Protocolsedited by Richard J. Sugrue.The use of monoclonal antibodies and lectins to identify changes in viral glycoproteins that are influenced by glycosylation : the case of respiratory syncytial virus attachment (G) glycoprotein / Joanna Rawling and José A. Melero -- Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS-CoV / Shuo Shen, Timothy H.P. Tan, and Yee-Joo Tan -- Analysis of glycoproteins of viruses in the family bunyaviridae / Xiaohong Shi and Richard M. Elliott -- Secretion of respiratory syncytial virus fusion protein from insect cells using the baculovirus expression system / Boon-Huan Tan, Gaie Brown, and Richard J. Sugrue -- Characterization of the dengue virus envelope glycoprotein expressed in Pichia pastoris / Boon-Huan Tan, Jian Lin Fu, and Richard J. Sugrue -- Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins / Alexander W. Tarr ... [et al.]. Viruses and glycosylation : an overview / Richard J. Sugrue -- Interaction between respiratory syncytial virus and glycosaminoglycans, including heparan sulfate / Louay K. Hallak, Steven A. Kwilas, and Mark E. Peeples -- Expression of the severe acute respiratory syndrome coronavirus 3a protein and the assembly of coronavirus-like particles in the baculovirus expression system / Sehaam Khan, Mah-Lee Ng, and Yee-Joo Tan -- The C type lectins DC-SIGN and L-SIGN : receptors for viral glycoproteins / Pierre-Yves Lozach ... [et al.] -- Functional analysis of the N-linked glycans within the fusion protein of respiratory syncytial virus / Ping Li ... [et al.] -- Expression and purification of viral glycoproteins using recombinant vaccinia viruses for functional and structural studies / Zhu-Nan Li and David A. Steinhauer -- The use of two-dimensional SDS-PAGE to analyze the glycan heterogeneity of the respiratory syncytial virus fusion protein / Terence P. McDonald and Richard J. Sugrue --
- 2008 SpringerSteven Tracy, M. Steven Oberste, Kristen M. Drescher, editors.Coxsackie B viruses: an introduction / B.W. Mahy -- Coxsackieviruses and quasispecies theory: evolution of enteroviruses / E. Domingo ... [et al.] -- Comparative genomics of the coxsackie B viruses and related enteroviruses / M.S. Oberste -- Group B coxsackievirus virulence / S. Tracy and C. Gauntt -- The coxsackievirus and adenovirus receptor / P. Freimuth, L. Philipson and S.D. Carson -- Coxsackievirus B RNA replication: lessons from poliovirus / P. Sean and B.L. Semler -- CVB translation: lessons from the polioviruses / J.M. Bonderoff and R.E. Lloyd -- Preferential coxsackievirus replication in proliferating/activated cells: implications for virus tropism, persistence, and pathogenesis / R. Feuer and J.L. Whitton -- The impact of CVB3 infection on host cell biology / D. Marchant ... [et al.] -- Host immune responses to coxsackievirus B3 / S. Huber -- Pediatric group B coxsackievirus infections / J.R. Romero -- CVB-induced pancreatitis and alterations in gene expression / A.I. Ramsingh -- The CVB and etiology of type 1 diabetes / K.M. Drescher and S.M. Tracy -- Persistent coxsackievirus infection: enterovirus persistence in chronic myocarditis and dilated cardiomyopathy / N.M. Chapman and K.S. Kim -- Autoimmunity in coxsackievirus infection / N.R. Rose -- CVB infection and mechanisms of viral cardiomyopathy / K.U. Knowlton.
- 2016 SpringerNicolas Goossens, Sophie Clément, Francesco Negro.1. Introduction -- 2. The HCV particle and its life cycle -- 3. Clinical features -- 4. Pathophysiology -- 5. Diagnosis -- 6. Management of HCV infection -- 7. Future challenges.
- 2012 SpringerBenhur Lee, Paul A. Rota, editors.Introduction: Nipah Virus--Discovery and Origin / Kaw Bing Chua -- Ecological Aspects of Hendra Virus / Hume Field, Gary Crameri, Nina Yu-Hsin Kung and Lin-Fa Wang -- Epidemiology of Henipavirus Disease in Humans / Stephen P. Luby and Emily S. Gurley -- Molecular Virology of the Henipaviruses / Paul A. Rota and Michael K. Lo -- Henipavirus Receptor Usage and Tropism / Olivier Pernet, Yao E Wang and Benhur Lee -- Henipavirus Membrane Fusion and Viral Entry / Hector C. Aguilar and Ronald M. Iorio -- Clinical and Pathological Manifestations of Human Henipavirus Infection / K. T. Wong and C. T. Tan -- Henipaviruses in Their Natural Animal Hosts / D. J. Middleton and H. M. Weingartl -- Nipah and Hendra Virus Interactions with the Innate Immune System / Christopher F. Basler -- Animal Challenge Models of Henipavirus Infection and Pathogenesis / Thomas W. Geisbert, Heinz Feldmann and Christopher C. Broder -- Diagnosis of Henipavirus Infection: Current Capabilities and Future Directions / Lin-Fa Wang and Peter Daniels -- Immunization Strategies Against Henipaviruses / Christopher C. Broder, Thomas W. Geisbert, Kai Xu, Dimitar B. Nikolov and Lin-Fa Wang, et al.
- 2016 SpringerYun-Fan Liaw, Fabien Zoulim.HBV Virology and Replication -- Experimental Models: Cell Culture and Animal Models -- Hepatitis B Virus Genotypes -- HBV Immunopathogenesis -- Carcinogenesis -- Hepatitis B Virus: Persistence and Clearance -- HDV Virology and Replication -- Translational Medicine in HBV?What Can We Learn from Clinical Samples? -- Global Epidemiology of HBV Infection -- Clinical Virology: Diagnosis and Virologic Monitoring -- Natural History of Hepatitis B Virus Infection -- Natural History of HBV Infection in the Community -- Occult HBV Infection -- The Basis for Antiviral Therapy: Drug Targets, Cross-Resistance and Novel Small Molecule Inhibitors -- IFN-Based Therapy and Management of Patients -- Nucleoside Analogue-Based Therapy and Management of Patients (Including HIV Co-infections, HBV and Pregnancy) -- Organ Transplantation in HBV Infected Patients -- Reactivation of Hepatitis B Virus Due to Cancer Chemotherapy and Other Immunosuppressive Drug Therapy -- Immunoprophylaxis of Hepatitis B Virus Infection and Its Sequelae -- Towards HBV Eradication.
- 2008 SpringerEmilio Jirillo, editor.Innate immunity in type C hepatitis / Tetsuo Takehara and Norio Hayashi -- Mechanisms of interferon action and resistance in chronic hepatitis C virus infection: lessons learned from cell culture studies / Srikanta Dash ... [et al.] -- Immunological parameters influencing adaptive immune responses to the hepatitis C virus / Patrick Bertolino, Geoffrey W. McCaughan, and David G. Bowen -- Immune responses against the hepatitis C virus and the outcome of therapy / Paul Klenerman and Eleanor Barnes -- Other microbial components associated with hepatitis C virus infection: their effects on interferon- a/ribavirin treatment / Luigi Amati, Vittorio Pugliese, and Emilio Jirillo -- Interferon-induced effector proteins and hepatitis C virus replication / Michael Frese and Eva Dazert -- Treatment of chronic hepatitis C with different genotypes / James Fung, Ching-Lung Lai, and Man-Fung Yuen -- Interferon treatment of hepatitis C virus infection: from basic biology to clinical application / Norihiro Furusyo, Masayuki Murata, and Jun Hayashi -- Interferon-based therapy for hepatitis C virus infections / Ming-Lung Yu and Wan-Long Chuang -- Treatment of chronic hepatitis C in "difficult-to-treat" patients in the clinical setting / Ana Moreno, Rafael Bárcena, and Carmen Quereda -- Effects of combined IFN-alpha/ribavirin treatment in HCV disease-related progression / Davide Festi ... [et al.] -- Pegylated interferons: clinical applications in the management of hepatitis C infection / S. James Matthews and Christopher McCoy.
- 2014 Springer Protocolsedited by Russell J. Diefenbach, Cornel Fraefel.HSV-1 biology and life cycle / Roger D. Everett -- Herpes simplex virus growth, preparation, and assay / Peggy Marconi and Roberto Manservigi -- Isolation of herpes simplex virus nucleocapsid DNA / Moriah Szpara -- Construction and characterization of bacterial artificial chromosomes (BACs) containing herpes simplex virus full-length genomes / Claus-Henning Nagel, Anja Pohlmann, and Beate Sodeik -- Engineering HSV-1 vectors for gene therapy / William F. Goins [and three others] -- Herpes simplex virus type 1 (HSV-1)-derived amplicon vectors / Matias E. Melendez, Cornel Fraefel, and Alberto L. Epstein -- HSV-1 amplicon vectors as genetic vaccines / Andrea S. Laimbacher and Cornel Fraefel -- Modification of HSV-1 to an oncolytic virus / Hiroshi Nakashima and E. Antonio Chiocca -- Herpes simplex virus mutant generation and dual-detection methods for gaining insight into latent/lytic cycles in vivo / Nancy M. Sawtell and Richard L. Thompson -- Phenotypic and genotypic testing of HSV-1 resistance to antivirals / Andreas Sauerbrei and Kathrin Bohn -- Using homogeneous primary neuron cultures to study fundamental aspects of HSV-1 latency and reactivation / Ju Youn Kim [and four others] -- Characterization of extracellular HSV-1 virions by proteomics / Roger Lippé -- Precipitation-based assay to analyze interactions of viral particles with cytosolic host factors / Kerstin Radtke, Fenja Anderson, and Beate Sodeik -- Affinity purification combined with mass spectrometry to identify herpes simplex virus protein-protein interactions / David G. Meckes Jr. -- Preparation of herpes simplex virus-infected primary neurons for transmission electron microscopy / Monica Miranda-Saksena, Ross Boadle, and Anthony L. Cunningham -- Multifluorescence live analysis of herpes simplex virus type-1 replication / Michael Seyffert [and three others] -- Expression, purification, and crystallization of HSV-1 glycoproteins for structure determination / Samuel D. Stampfer and Ekaterina E. Heldwein -- Cryo-EM techniques to resolve the structure of HSV-1 capsid-associated components / Ryan H. Rochat, Corey W. Hecksel, and Wah Chiu -- In vivo HSV-1 DNA transport studies using murine retinal ganglion cells / Jolene M. Draper, Graham S. Stephenson, and Jennifer H. LaVail -- HSV-1 protein expression using recombinant baculoviruses / Lorry M. Grady, Ping Bai, and Sandra K. Weller -- Murine intravaginal HSV-2 challenge model for investigation of DNA vaccines / Joshua O. Marshak, Lichun Dong, and David M. Koelle.
- 2006 kargervolume editors, Gerd Gross, Hans-Wilhelm Doerr.Molecular biology of varicella-zoster virus / Rahaus, M., Desloges, N., Wolff, M.H -- Latency and reactivation of VZV / Lungu, O., Gershon, A.A. -- Laboratory confirmation of herpes zoster / Ludwig, B., Buxbaum, S., Doerr, H.W. -- Clinical picture and complications of herpes zoster: the view of the dermatologist / Gross, G. -- Ophthalmic manifestations of herpes zoster infection / Guembel, H. -- (Herpes) zoster oticus / Pau, H.W. -- Neuroanatomy of pain and neuropathology of herpes zoster and postherpetic neuralgia / Wree, A., Usunoff, K.G. -- Postherpetic neuralgia and other neurologic complications / Baron, R. -- Varicella-zoster virus infections during pregnancy / Sauerbrei, A., Wutzler, P. -- Herpes zoster in the immunocompromised host / Schöfer, H. -- Chickenpox and zoster in marrow transplant recipients / Genvresse, I., Maschmeyer, G. -- General aspects of therapy / Gross, G. -- Antiviral therapy of shingles in dermatology / Lilie, H.M., Wassilew, S.W. -- Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d] pyrimidine nucleoside analogues (BCNAS) / Clercq, E.D. -- Therapy of zoster pain, postherpetic neuralgia and other neurological complications / Baron, R. -- Epidemiology of herpes zoster: what has changed? / Allwinn, R., Buxbaum, S., Doerr, H.W. -- Live attenuated varicella vaccine / Gershon, A.A.
- 2014 SpringerRalph Pantophlet, editor.Glycosylation is a common and extremely important modification in biological molecules, particularly of proteins. HIV Glycans in Infection and Immunity provides an overview of the roles of glycans in the transmission/infection, antigenicity, and immunogenicity of HIV and the HIV envelope glycoprotein. It explores recent advances in the understanding of the impact of HIV glycans in infection and their promise for immunological and therapeutic intervention. Novel collaborations between glycobiologists and immunologists in recent years have led to key advances in the understanding of HIV glycans. These cross-disciplinary endeavors, their achievements and their impact on the field are all addressed, herein.-- Source other than Library of Congress.
- 2013 SpringerLi Wu, Olivier Schwartz, editors.Also available: Print – 2013
- 2011 SpringerNigel Curtis, Adam Finn, Andrew J. Pollard, editors.The value of vaccination / David E. Bloom -- Recent trends in global immunisation / Gustav J.V. Nossal -- New advances in typhoid fever vaccination strategies / Zulfiqar A. Bhutta ... [et al.] -- Prevention of vertical transmission of HIV in resource-limited countries / Catherine M. Wilfert ... [et al.] -- Pneumonia in children in developing countries / Frank Shann -- Darwin, microbes and evolution by natural selection / E. Richard Moxon -- Human herpesvirus 6 / Charles G. Prober -- Advances in the diagnosis and management of central venous access device infections in children / Asha Bowen and Jonathan Carapetis -- Moraxella catarrhalis-pathogen or commensal? / Christoph Aebi -- Anaerobic infections in children / Itzhak Brook -- Encephalitis diagnosis and management in the real world / Sarah S. Long -- Toxic shock syndrome-evolution of an emerging disease / James K. Todd -- Dissection of B-cell development to unravel defects in patients with a primary antibody deficiency / Mirjam van der Burg ... [et al.] -- Mumps is back : why is mumps eradication not working? / Noni Macdonald ... [et al.] -- Neonatal herpes simplex virus infections: where are we now? / Clara Thompson and Richard Whitley -- Rational approach to pediatric antifungal therapy / William J. Steinbach -- Antiviral therapy of CMV disease in children / Mike Sharland ... [et al.] -- Infectious hazards from pets and domestic animals / Mona Al-Dabbagh and Simon Dobson -- Novel technology to study co-evolution of humans and Staphylococcus aureus: consequences for interpreting the biology of colonisation and infection / Alex van Belkum -- A practical approach to eosinophilia in a child arriving or returning from the tropics / Penelope Bryant and Nigel Curtis.Also available: Print – 2011
- 2012 SpringerJames A. Radosevich, editor."HPV and Cancer" is a concise read that covers all aspects of the Human Papilloma Virus as it relates to human cancers. While written by professionals, it design to be understandable by those that are not in the field, yet it has the technical details that professionals want to stay abreast of this changing field. The book starts out the history of HPV and progresses into the molecular biology of the virus and our current understand of the structure and functions of the proteins and genes it encodes.
- 2015 SpringerCarole Fakhry, Gypsyamber D'Souza, editors.Anatomical sites and subsites of head and neck cancer -- Epidemiology of oral HPV infection and HPV-associated head and neck cancer -- Frequent behavioural questions with an HPV-positive malignancy of the head and neck -- The molecular biology of HPV-related head and neck cancer -- The diagnosis of HPV-related head and neck squamous cell carcinoma: Recognition of its microscopic appearance and the use of ancillary detection assays -- Clinical management of HPV-related oropharyngeal cancer -- The role of vaccines for HPV-related head and neck cancers -- The care of the HPV-negative head and neck cancer patient: Presentation, prognosis, treatment. .
- 2008 SpringerScott K. Dessain, editor.Therapeutic control of hepatitis C virus: the role of neutralizing monoclonal antibodies / Z. Y. Keck ... [et al.] -- Antibodies for HIV treatment and prevention: window of opportunity? / M. Huber ... [et al.] -- Human monoclonal antibody and vaccine approaches to prevent human rabies / T. Nagarajan ... [et al.] -- Immunoprophylaxis of RSV infection: advancing from RSV-IGIV to palivizumab and motavizumab / H. Wu ... [et al.] -- The molecular basis of antibody protection against West Nile virus / E. Mehlhop ... [et al.] -- Exploring the native human antibody repertoire to create antiviral therapeutics / S. K. Dessain ... [et al.].
- 2008 Kargervolume editors, John Nicholas, Kuan-Teh Jeang, T.-C. Wu.Molecular epidemiology of human papillomavirus infection -- / Gillison, M.L -- Molecular pathogenesis of the human papillomavirus / Mao, C.-P., Wu, T.-C -- Human papillomavirus vaccines / Roden, R., Hung, C.-F., Monie, A., Wu, T.-C -- Hepatitis C virus genetics and the discovery of mechanism based inhibitors of the Ns3/4A protease and NS5B polymerase / LaFemina, R.L -- Role of the hepatitis B virus in hepatocellular carcinoma / Toh, S.-T., Lee, C.G -- Carcinogenesis induced by hepatitis B virus / Cougot, D., Buendia, M.-A., Neuveut, C -- Disease and pathogenesis associated with Epstein-Barr virus / Ambinder, R.F -- The biology and molecular biology underlying Epstein-Barr virus oncogenesis / Martin, H.J., Hayward, S.D -- Kaposi-sarcoma-associated herpesvirus clinical diseases and viral pathogenesis / Damania, B., Dittmer, D.P. -- Molecular biology of human herpesvirus 8 neoplasia / Chaudhary, P.M., Nicholas, J -- Human cancer viruses. Human T cell leukemia virus type 1 and 2: mechanisms of pathogenesis / Arnold, J., Green, P.L -- Chromosomal instability and human T cell leukemia virus 1 transformation / Chi, Y.-H., Jeang, K.-T.
- 2008 SpringerThomas E. Shenk, Mark F. Stinski, editors.Human cytomegalovirus genome / E. Murphy and T. Shenk -- Human cytomegalovirus microRNAs / P.J. Fannin Rider ... [et al.] -- Mutagenesis of the cytomegalovirus genome / Z. Ruzsics and U.H. Koszinowski -- Cytomegalovirus cell tropism / C. Sinzger, M. Digel and G. Jahn -- Virus entry and innate immune activation / M.K. Isaacson, L.K. Juckem and T. Compton -- Functions of human cytomegalovirus tegument proteins prior to immediate early gene expression / R.F. Kalejta -- Initiation of cytomegalovirus infection at ND10 / G.G. Maul -- Functional roles of the human cytomegalovirus essential IE86 protein / M.F. Stinski and D.T. Petrik -- Nuts and bolts of human cytomegalovirus lytic DNA replication / G.S. Pari -- Interactions of human cytomegalovirus proteins with the nuclear transport machinery / T. Stamminger -- Structure and formation of the cytomegalovirus virion / W. Gibson -- Human cytomegalovirus modulation of signal transduction / A.D. Yurochko -- Chemokines and chemokine receptors encoded by cytomegaloviruses / P.S. Beisser ... [et al.] -- Subversion of cell cycle regulatory pathways / V. Sanchez and D.H. Spector -- Modulation of host cell stress responses by human cytomegalovirus / J.C. Alwine -- Control of apoptosis by human cytomegalovirus / A.L. McCormick -- Aspects of human cytomegalovirus latency and reactivation / M. Reeves and J. Sinclair -- Murine model of cytomegalovirus latency and reactivation / M.J. Reddehase ... [et al.] -- Cytomegalovirus immune evasion / C. Powers ... [et al.] -- Cytomegalovirus vaccine development / M.R. Schleiss -- Cytomegalovirus infection in the human placenta: maternal immunity and developmentally regulated receptors on trophoblasts converge / L. Pereira and E. Maidji -- Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing / D.N. Streblow ... [et al.] -- Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease / W. Britt.
- 2014 Springer Protocolsedited by Andrew D. Yurochko, William E. Miller.History of the molecular biology of cytomegaloviruses / Mark F. Stinski -- Overview of human cytomegalovirus pathogenesis / Maciej T. Nogalski, Donna Collins-McMillen, and Andrew D. Yurochko -- Distinct properties of human cytomegalovirus strains and the appropriate choice of strains for particular studies / Giada Frascaroli and Christian Sinzger -- Use of diploid human fibroblasts as a model system to culture, grow, and study human cytomegalovirus infection / Elizabeth A. Fortunato -- Use of recombinant approaches to construct human cytomegalovirus mutants / Iryna Dekhtiarenko, Luka éCiécin-éSain, and Martin Messerle -- Use of primary human cells (fibroblasts, monocytes, and others) to assess human cytomegalovirus function / Emma Poole, Matthew Reeves, and John H. Sinclair -- Hematopoietic long-term culture (hLTC) for human cytomegalovirus latency and reactivation / Mahadevaiah Umashankar and Felicia Goodrum -- Analysis of cytomegalovirus binding/entry-mediated events / Gary C.T. Chan and Andrew D. Yurochko -- Use of 5-Ethynyl-2' -deoxyuridine labelling and flow cytometry to study cell cycle-dependent regulation of human cytomegalovirus gene expression / Lèuder Wiebusch and Christian Hagemeier -- Methods for studying the function of cytomegalovirus GPCRs / Christine M. O'Connor and William E. Miller -- Methods for the detection of cytomegalovirus in glioblastoma cells and tissues / Charles S. Cobbs, Lisa Matlaf, and Lualhati E. Harkins -- Methods to study the nucleocytoplasmic transport of macromolecules with respect to their impact on the regulation of human cytomegalovirus gene expression / Marco Thomas ... [et al.] -- Fluorescence-based laser capture microscopy technology facilitates identification of critical in vivo cytomegalovirus transcriptional programs / Craig N. Kreklywich ... [et al.] -- Techniques for characterizing cytomegalovirus-encoded miRNAs / Lauren M. Hook ... [et al.] -- What we have learned from animal models of HCMV / Pranay Dogra and Tim E. Sparer -- Rodent models of congenital cytomegalovirus infection / Djurdjica Cekinovic, Vanda Juranic Lisnic, and Stipan Jonjic -- Recent approaches and strategies in the generation of antihuman cytomegalovirus vaccines / Suresh B. Boppana and William J. Britt -- Approaches for the generation of new anti-cytomegalovirus agents : identification of protein-protein interaction inhibitors and compounds against the HCMV IE2 protein / Beatrice Mercorelli ... [et al.].
- 2006 ScienceDirecteditors, Gerhard Krueger, Dharam Ablashi.
- 2013 SpringerStuart LeGrice, Matthias Gotte, editors.Development of the First AIDS Drugs: AZT and Other Dideoxynueosides / Robert Yarchoan, Hiroaki Mitsuya -- Part I: Structure and Function of HIV RT. Proviral DNA Synthesis in HIV: Background / Dorota Piekna-Przybylska Ph.D., Robert A. Bambara Ph.D. -- The RNase H Domain: Structure, Function and Mechanism / Marcin Nowotny, Małgorzata Figiel -- Conformational Dynamics of Reverse Transcription / Stuart F. J. LeGrice -- Part II: Mechanism of Action of Approved RT Inhibitors. Nucleoside RT Inhibitors: Structural and Molecular Biology / Gaofei Lu, Antonio J. Acosta-Hoyos, Walter A. Scott -- Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) / Kalyan Das Ph.D., Eddy Arnold Ph.D., Stephen H. Hughes Ph.D. -- Part III: Alternative Strategies to Interfere with the Function of HIV RT. Ribonuclease H Inhibitors: Structural and Molecular Biology / Jason W. Rausch -- Targeting Small Molecules and Peptides to the p66-p51 Reverse Transcriptase Interface / Daouda Abba Moussa, Audrey Agopian, Gilles Divita -- Targeting RT Translocation / Gregory L. Beilhartz, Brian J. Scarth, Matthias Götte -- tRNA Primer Sequestration as an Antiviral Strategy / Christopher P. Jones, Karin Musier-Forsyth -- Part IV: HIV Genetic Variability and the Problem of Drug Resistance. HIV Reverse Transcriptase Fidelity, Clade Diversity, and Acquisition of Drug Resistance / Luis Menéndez-Arias -- APOBECs and Their Role in Proviral DNA Synthesis / John S. Albin, Reuben S. Harris -- Role of RNase H Activity in NRTI/NNRTI Drug Resistance / Gilda Tachedjian B.Sc. (Hons), Ph.D., Nicolas Sluis-Cremer B.Sc. (Hons), Ph.D. -- HIV Population Dynamics / Mary Kearney, John Coffin -- Part V: Prevention and Future Approaches. RT Inhibitors as Microbicides / Jan Balzarini.
- 2005 Springer Protocolsedited by Clare Davy, John Doorbar.Analysis of HPV DNA replication using transient transfection and cell-free assays / Bing Yuan Lin, Thomas R. Broker, and Louise T. Chow -- Detection and quantitation of HPV DNA replication by southern blotting and real-time PCR / Iain M. Morgan and Ewan R. Taylor -- Analysis of E7/RB associations / Sandra Caldeira, Wen Dong, and Massimo Tommasino -- Transformation assays for HPV oncoproteins / Paola Massimi and Lawrence Banks -- Analysis of adeno-associated virus and hpv interaction / Paul L. Hermonat ... [et al.] -- In vitro assays of substrate degradation induced by high-risk HPV E6 oncoproteins / Miranda Thomas and Lawrence Banks -- Measuring the induction or inhibition of apoptosis by HPV proteins / Anna M. Kowalczyk ... [et al.] -- Codon optimization of papillomavirus genes / Martin Muller -- Generation of HPV pseudovirions using transfection and their use in neutralization assays / Christopher B. Buck ... [et al.] -- Generation and application of HPV pseudovirions using vaccinia virus / Martin Sapp and Hans-Christoph Selinka. Differentiation of HPV-containing cells using organotypic "raft" culture or methylcellulose / Regina Wilson and Laimonis A. Laimins -- Propagation of infectious, high-risk HPV in organotypic "raft" culture / Margaret E. McLaughlin-Drubin and Craig Meyers -- Retrovirus-mediated gene transfer to analyze HPV gene regulation and protein functions in organotypic "raft" cultures / N. Sanjib Banerjee, Louise T. Chow, and Thomas R. Broker -- The HPV xenograft severe combined immunodeficiency (scid) mouse model / William Bonner -- The cottontail rabbit papillomavirus model of high-risk HPV-induced disease / Janet L. Brandsma -- Studying the HPV lifecycle in 3A trophoblasts and resulting pathophysiology / Yong Liu, Hong You, and Paul L. Hermonat -- Replication and encapsidation of papillomaviruses in saccharomyces cerevisiae / Peter C. Angeletti -- Analysis of the regulation of viral transcription / Bernd Gloss, Mina Kalantari, and Hans-Ulrich Bernard -- Analysis of HPV transcripts by RPA / Jason M. Bodily and Craig Meyers -- Analysis of regulatory motifs within HPV transcripts / Sarah A. Cumming and Sheila V. Graham -- Detection of HPV transcripts by nested RT-PCR / Christine Mant, Barbara Kell, and John Cason -- Identification of new papillomavirus types / Ethel-Michele de Villiers, Corinna Whitley, and Karin Gunst -- Identification of HPV variants / John Cason, Jon Bible, and Christine Mant -- Histochemical analysis of cutaneous HPV-associated lesions / Kiyofumi Egawa -- Histochemical analysis of cervical intraepithelial neoplasia / Michael Babawale ... [et al.] -- Detection of papillomavirus proteins and DNA in paraffin-embedded tissue sections / Woei Ling Peh and John Doorbar -- Detection and quantitation of HPV gene expression using real-time PCR / Rashmi Seth ... [et al.] -- Analysis of P16INK4A and integrated genomes as progression markers / Svetlana Vinokurova, Nicolas Wentzensen, and Magnus von Knebel Doeberitz -- Use of biomarkers in the evaluation of CIN grade and progression of early CIN / Jan P.A. Baak and Arnold-Jan Kruse -- HPV DNA detection and typing in cervical scrapes / Peter J. F. Snijders ... [et al.] -- HPV DNA detection and typing in inapparent cutaneous infections and premalignant lesions / Maurits de Koning ... [et al.] -- Establishing HPV-containing keratinocyte cell lines from tissue biopsies / Margaret Anne Stanley -- Using an immortalized cell line to study the HPV lifecycle in organotypic "raft" cultures / Paul F. Lambert ... [et al.] --
- 2014 CRCnetBASEedited by Sunit K. Singh.
- 2007 ScienceDirecteditor, Albert Bosch.
- 2012 SpringerMark von Itzstein, editor.
- 2012 SpringerSelene Baschieri, editor.Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination. Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may result ineffective and, above all, may
- 2013 SpringerBryan R. Cullen, editor.The APOBEC3 Family of Retroelement Restriction Factors / Eric W. Refsland, Reuben S. Harris -- Inhibition of Retroviral Replication by Members of the TRIM Protein Family / Adam J. Fletcher, Greg J. Towers -- The Antiviral Activities of Tetherin / Stuart J. D. Neil -- Restriction of Retroviral Infection of Macrophages / Mark Sharkey -- Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors / Welkin E. Johnson -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants / György Szittya, József Burgyán -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates / Arabinda Nayak, Michel Tassetto, Mark Kunitomi, Raul Andino -- Roles of MicroRNAs in the Life Cycles of Mammalian Viruses / Eva Gottwein -- Interplay Between DNA Tumor Viruses and the Host DNA Damage Response / Karyn McFadden, Micah A. Luftig.
- 2014 SpringerGauri Mankekar, editor.Incidence of invasive fungal sinusitis has been increasing over the years. The understanding of its pathophysiology has improved with newer serological tests and diagnostic methods helping in earlier diagnosis and reducing patient morbidity. It was believed earlier that invasive fungal sinusitis is seen only in immune compromised patients but clinical reports suggest otherwise. More anti-fungal drugs are being added to improve incidence of patient survival. This book aims to compile all practical information about invasive fungal sinusitis into a single volume. Therefore, busy clinicians would not have to perform exhaustive literature studies to diagnose invasive fungal sinusitis. The book aims to provide an overview of diseases which could be mistaken for invasive fungal sinusitis and discuss how the management is different. Book sections consist of clinical, microbiological, serological, pathological, radiological and pharmacological features of the disease and its management. Each section is important in today's context as it dynamically alters the management of the patient. Early clinical suspicion and rapid microbiological, pathological and radiological diagnosis with aggressive treatment with surgical debridement and medical therapy leads to favorable outcomes.
- 2015Charlotte DeCroes Jacobs."He first full biography of Jonas Salk offers a complete picture of the enigmatic figure, from his early years working on an influenza vaccine--for which he never fully got credit--to his seminal creation of the Polio vaccine, up through his later work to find a cure for AIDS"-- Provided by publisher.
- 2007 SpringerC. Boshoff and R.A. Weiss (eds.).Modern evolutionary history of the human KSHV genome / G.S. Hayward and J.-C. Zong -- Rhesus monkey rhadinovirus : a model for the study of KSHV / C.M. O'Connor and D.H. Kedes --the Rta/Orf50 transactivator proteins of the gamma-herpesviridae / M.R. Staudt and D.P. Dittmer -- Structure and function of latency-associated nuclear antigen / S.C. Verma, K. Lan, and E. Robertson -- The KSHV and other human herpesviral G protein-coupled receptors / M. Cannon -- Regulation of KSHV lytic gene expression / H. Deng, Y. Liang, and R. Sun -- Karposi sarcoma herpesvirus-encoded interferon regulator factors / M.K. Offermann -- Endothelial cell- and lymphocyte-based in vitro systems for understanding KSHV biology / S.C. McAllister and A.V. Moses -- KSHV after an organ transplant : should we screen? / A.-G. Marcelin, V. Calvez, and E. Dussaix -- Kaposi sarcoma-associated herpesvirus and other viruses in human lymphomagenesis / E. Cesarman and E.A. Mesri -- The use of antiviral drugs in the prevention and treatment of Kaposi sarcoma, multicentric Castleman disease / C. Casper and A. Wald -- Interactions between HIV-1 Tat and KSHV / Y. Aoki and G. Tosato.Also available: Print – 2007
- 2007 Springeredited by Janos Minarovits, Eva Gonczol, Tibor Valyi-Nagy.
- 2012 Springerby David Escors, Karine Breckpot, Frederick Arce, Grazyna Kochan, Holly Stephenson.Annotation Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale clinical trials to cure severe immunodeficiency in children. However, their successes were overshadowed some time later by the occurrence of vector-related leukaemia in a number of treated children. It is in this context that lentiviral vectors have appeared, with improved efficiency and, possibly, increased biosafety. Very recently, the first clinical trials with lentivectors have been carried out with some success. This Brief firstly defines gene therapy, and places lentivectors within this fascinating therapeutic strategy. Then follows a comprehensive description of the development of retroviral and lentiviral vectors and how to specifically target distinct cell types and tissues. The authors also discuss the application of lentivector gene therapy for the treatment of cancer and autoimmune diseases, ending with the application of lentivectors in human gene therapy clinical trials.
- 2009 SpringerJames L. Van Etten, editor.The Phycodnaviridae : The story of how tiny giants rule the world / W.H. Wilson, J.L. Etten and M.J. Allen -- African swine fever virus / E.R. Tulman [and others] -- Mimivirus / J.M. Claverie, C. Abergel and H. Ogata -- Family Iridoviridae : poor viral relations no longer / V.G. Chinchar [and others] -- Ascoviruses: Superb Manipulators of Apoptosis for Viral Replication and Transmission / B.A. Federici [and others] -- Whispovirus / J.H. Leu [and others] -- Jumbo bacteriophages / R.W. Hendrix.
- 2014 CRCnetBASEedited by Dongyou Liu.Security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants. Throughout history, these microbes and toxins have been exploited in one form or another as biowarfare and bioterror agents that create fear and panic well beyond any actual physical damages they might cause. Manual of Security Sensitive Microbes and Toxins provides comprehensive, state-of-the-art coverage of microbes and toxins of biosecurity concern.
- 2012 SpringerGyörgy Berencsi, editor.
- 2005 SpringerM. Marsh (ed.).Viral entry / S.B. Sieczarski and G.R. Whittaker -- The many mechanisms of viral membrane fusion proteins / L.J. Earp ... [et al.] -- The role of the cytoskeleton during viral infection / K. Döhner and B. Sodeik --Nuclear import in viral infections / U.F. Greber and M. Fornerod -- Viral RNA replication in association with cellular membranes / A. Salonen, T. Ahola, and L. Kääriäinen -- Synthesis and quality control of viral membrane proteins / C. Maggioni and I. Braakman -- Receptor modulation in viral replication : HIV, HSV, HHV-8 and HPV : same goal, different techniques to interface with MHC-I antigen presentation / V. Piguet -- Trafficking of viral membrane proteins / R. Byland and M. March.
- 2011 Springer Protocolsedited by Otto Holst.Part I: Bacterial protein toxins -- Detection of bacterial protein toxins by solid phase magnetic immunocapture and mass spectrometry / Gabriella Pocsfalvi and Gitta Schlosser -- Sensitive and rapid detection of cholera toxin-producing Vibrio cholerae using loop-mediated isothermal amplification / Wataru Yamazaki -- Ultrasensitive detection of botulinum neurotoxins and anthrax lethal factor in biological samples by ALISSA / Karine Bagramyan and Markus Kalkum -- Examination of Bacillus anthracis spores by multiparameter flow cytometry / William C. Schumacher [and others] -- A cell-based fluorescent assay to detect the activity of shiga toxin and other toxins that inhibit protein synthesis / Shane Massey, Beatriz Quiñones, and Ken Teter -- Use of a vero cell-based fluorescent assay to assess relative toxicities of shiga toxin 2 subtypes from Escherichia coli / Beatriz Quiñones and Michelle S. Swimley -- Molecular methods: chip assay and quantitative real-time PCR: in detecting hepatotoxic cyanobacteria / Anne Rantala-Ylinen, Hanna Sipari, and Kaarina Sivonen -- Part II: Endotoxins -- Capillary electrophoresis chips for fingerprinting endotoxin chemotypes from whole-cell lysates / Béla Kocsis [and others] -- Isolation of smooth-type lipopolysaccharides to electrophoretic homogeneity / Elder Pupo -- A method for unobtrusive labeling of lipopolysaccharides with quantum dots / Carlos Morales-Betanzos, Maria Gonzalez-Moa, and Sergei A. Svarovsky -- Fluorescence-based methods to assay inhibitors of lipopolysaccharide synthesis / Marcy Hernick -- Micromethods for lipid a isolation and structural characterization / Martine Caroff and Alexey Novikov -- Two efficient methods for the conjugation of smooth-form lipopolysaccharides with probes bearing hydrazine or amino groups. I. LPS activation with cyanogen bromide / Fernando Battaglini and Diego Pallarola -- Two efficient methods for the conjugation of smooth-form lipopolysaccharides with probes bearing hydrazine or amino groups. II. LPS activation with a cyanopyridinium agent / Fernando Battaglini and Diego Pallarola -- Part III: Mold fungus toxins -- Extraction and analysis of fumonisins and compounds indicative of fumonisin exposure in plant and mammalian tissues and cultured cells / Nicholas C. Zitomer and Ronald T. Riley -- Determination of fumonisins B1 and B2 in maize food products by a new analytical method based on high-performance liquid chromatography and fluorimetric detection with post-column derivatization / Marilena Muscarella [and others] -- A confirmatory method for aflatoxin M1 determination in milk based on immunoaffinity cleanup and high-performance liquid chromatography with fluorometric detection / Marilena Muscarella [and others] -- Simultaneous determination of aflatoxins B1, B2, G1, and G2 in foods and feed materials / Marilena Muscarella [and others] -- Highly sensitive PCR-based detection specific to Aspergillus flavus / Amaia González-Salgado -- A rapid enzymatic method for aflatoxin B detection / Danila Moscone, Fabiana Arduini, and Aziz Amine.
- 2014 SpringerFalk Nimmerjahn, editor.This book focuses on the function of antibodies in vivo. Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. These new results dramatically changed our view of how antibodies function in vivo. The importance of this class of molecules is demonstrated by the heightened susceptibility to infections of humans and mice with an altered capacity to generate pathogen specific antibody responses. Thus, the majority of our currently available vaccines, such as vaccines against influenza, measles and hepatitis focus on the generation of long lasting antibody responses. Recent evidence from a variety of in vivo model systems and from human patient cohorts has highlighted the exclusive role of cellular Fc-receptors for certain immunoglobulin isotypes and subclasses. With the recent discovery of a human Fc-receptor for IgM all different human immunoglobulin isotypes now have a cellular receptor, providing a feedback mechanism and link between antibodies and the cellular components of the immune system. Moreover it has become clear the complement and Fc-receptor system are tightly connected and regulate each other to ensure a well balanced immune response. Among the immunoglobulin isotypes IgG plays a very important protective role against microbial infections and also as a therapeutic agent to kill tumor cells or autoantibody producing B cells in autoimmune disease. Transfer of our knowledge about the crucial function of Fc-receptors has led to the production of a second generation of therapeutic antibodies with enhanced binding to this class of receptors. Binding of antibodies to Fc-receptors leads to the recruitment of the potent pro-inflammatory effector functions of cells from the innate immune system. Hence, Fc-receptors link the innate and adaptive immune system, emphasizing the importance of both arms of the immune system and their crosstalk during anti-microbial immune responses. Besides this pro-inflammatory activity immunoglobulin G (IgG) molecules are long known to also have an anti-inflammatory function. This is demonstrated by the use of high dose intravenous immunoglobulins as a therapeutic agent in many human autoimmune diseases. During the past five years several new insights into the molecular and cellular pathways of this anti-inflammatory activity were gained radically changing our view of IgG function in vivo. Several lines of evidence suggest that the sugar moiety attached to the IgG molecule is responsible for these opposing activities and may be seen as a molecular switch enabling the immune system to change IgG function from a pro- to an anti-inflammatory activity. There is convincing evidence in mice and humans that aberrant IgG glycosylation could be an important new pathway for understanding the impaired antibody activity during autoimmune disease. Besides this tremendous increase in basic knowledge about factors influencing immunoglobulin activity the book will also provide insights into how these new insights might help to generate novel therapeutic approaches to enhance IgG activity for tumor therapy on the one hand, and how to block the self-destructive activity of IgG autoantibodies during autoimmune disease on the other hand.
- 2010 SpringerSunil K. Lal, editor.The SARS outbreak in 2002 caused unprecedented devastation and exhibited unusually high rates of morbidity and mortality. For the SARS coronavirus, the transmission vehicle was man. What added to the spread was man's convenient, rapid and affordable ways of travel that caused the virus to spread globally in a short span of time. The SARS coronavirus jumped the species barrier, similar to many recent zoonotic diseases, avian flu, swine flu, Nipah and encephalitis virus. It is extremely important for us to understand the enemy before it strikes again in order to be able to combat such outbreaks as and when they occur. Molecular mechanisms that the virus exploits within its host and that result in infection and pathogenesis are the key to being able to block its transmission cycle. In this book, leading scientists from around the globe have discussed molecular aspects of viral entry, replication, viral gene expression, pathogenesis and host immune response against the SARS coronavirus.
- 2013 SpringerSusanne Modrow, Dietrich Falke, Uwe Truyen, Hermann Schätzl.The book gives a comprehensive overview on the knowledge of virus infection relevant for humans and animals. For each virus family the molecular details of the virus particle and the viral replication cycle are described. In the case of virus types with relevance for human and/or animal health the data on molecular biology, genetics and virus-cell interaction are combined with those concerning, pathogenesis, epidemiology, clinics, prevention and therapy.
- 2013 SpringerBina Pani Das.Japanese Encephalitis (JE), a mosquito borne disease, is the leading cause of viral encephalitis in 14 Asian countries due to its epidemic potential, high case fatality rate and increased possibility of lifelong disability in patients who recover from this dreadful disease. In spite of seriousness of the disease, still only few books are available for ready reference. Hence, this book will be useful for students, entomologists, paramedical staff and vector control managers in public health.Of the thousand suspected JE deaths in India annually, more than 75% is contributed by Northern India wherein disease transmission failed to be explained based on entomological evidence due to inadequate mosquito surveillance tool used in determining JE vector density. In order to overcome the above problem, Dr Bina Pani Das, the author of this book, developed "BPD hop cage method", a simple, cost effective, and operationally feasible surveillance tool specially designed to capture predominantly day resting adult Cx. tritaeniorhynchus mosquitoes, the principal JE vector species in the country from land and aquatic vegetation.
- 2006 SpringerStephen K. Tyring (ed.).The role of mucosal immunity in protection against viral diseases / Vandana Madkan, Karan Sra, and Stephen K. Tyring -- Anogenital mucosal immunology and virology / Anthony Simmons -- Gastrointestinal mucosal immunology / David A. Bland, Carlos A. Barrera, and Victor E. Reyes -- Virology of the gastrointestinal tract / Richard L. Ward ... [et al.] -- Oral manifestations of viral diseases / Denis P. Lynch -- Common respiratory viruses and pulmonary mucosal immunology / David B. Huang -- Ophthalmic manifestations of viral diseases / Steven Yeh and Mitchell P. Weikert.
- 2015Mary Moran, Nick Chapman, Lisette Abela-Oversteegen, Vipul Chowdhary, Anna Doubell, Christine Whittall, Rachel Howard, Penny Farrell, Dale Halliday, Catherine Hirst.In 2014, a reported $3,377m was invested in neglected disease R&D, consisting of $3,197m from repeat survey participants (called year-on-year -- YOY -- funders) and $179m from irregular survey participants. Total YOY funding for neglected disease R&D increased by $150m (up 4.9%), but this was entirely the result of significant new investment in Ebola R&D in response to the 2014 West African Ebola epidemic. Without Ebola, YOY funding for neglected disease R&D would have been essentially unchanged from 2013 (down $14m, -0.4%).
- 2016 SpringerRobert G. Wallace, Rodrick Wallace, editors.1. Did ebola emerge in West Africa by a policy-driven phase change in agroecology? -- 2. Ebola in the hog sector: modeling pandemic emergence in commodity livestock -- 3. Did neoliberalizing West Africa's forests produce a vaccine-resistant ebola? -- 4. Introducing pandemic control theory -- 5. The social amplification of pandemics and other disasters -- Index.
- 2013 CRCnetBASEedited by Sunit K. Singh, Daniel Ruzek.Neuroviral infections : a historical perspective -- Neuroviral infections and immunity -- Controlling neuroinflammation : lessons from rabies virus -- Laboratory diagnosis of CNS viral infections -- New trends in antiviral therapy of CNS infections -- Animal models of viral encephalitis -- Herpes simplex virus and human CNS infections -- CNS, neurological infections caused by the herpes virus Varicella zoster virus (VZV) and models of VZV-neurotropism -- Epstein- Barr virus and CNS infections -- Cytomegalovirus (CMV) infection -- Human herpesvirus 6A, 6B, and 7 encephalitis -- The human polyomavirus JC and progressive multifocal leukoencephalopathy.
- 2013 CRCnetBASEedited by Sunit K. Singh, Daniel Ruzek.Alphavirus neurovirulence -- Neurological chikungunya : lessons from recent epidemics, animal models, and other alphavirus family members -- Arenaviruses and neurovirology -- Bunyaviruses -- Human coronaviruses : respiratory pathogens revisited as infectious neuroinvasive, neurotropic, and neurovirulent agents -- Non-polio enteroviruses, polioviruses, and human CNS infections -- Neurovirulence of West Nile Virus -- Murray Valley encephalitis virus -- Japanese encephalitis virus and human CNS infection -- Tick Borne Encephalitis Virus (TBEV) infection -- Saint Louis encephalitis -- Powassan virus infection -- Neurological Dengue -- Influenza virus and CNS infections -- Human paramyxoviruses and infections of the central nervous system -- Rabies virus neurovirulence -- Rubella virus infections -- Human T-lymphotropic virus -- Human Immunodeficiency Virus (HIV) neuropathogenesis.
- 2014 ScienceDirectedited by Alex C. Tselis and John Booss.This volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology. Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere.
- 2006 SpringerStanley Perlman, Kathryn V. Holmes, editors.Viral RNA synthesis -- Protein synthesis, structure, and processing -- Viral assembly and release -- Viral entry -- Pathogenesis of non-human coronaviruses -- Pathogenesis of arteriviruses and toroviruses -- Pathogenesis of human coronaviruses -- Vaccines, antiviral drugs, and diagnostics.
- 2013 SpringerManmohan Singh, editor.
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