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Vascular Diseases

  • Trends in neurovascular surgery / Brian A. O'Shaughnessy [and others] -- Trends in endovascular surgery / Demetrius K. Lopes [and others] -- Novel approaches to neurovascular diseases / Michael L. DiLuna, Katie Pricola, and Murat Gunel -- Implications of trends in the marketplace for neurovascular diseases / Charles B. Wilson -- Neuroendovascular diseases: past, present, and future / Joseph M. Fitzgerald and Daniel Tuden -- Unruptured aneurysms: a neurological perspective / Nerissa U. Ko and Daryl R. Gress -- Unruptured aneurysms: a surgical perspective / Chirag D. Gandhi, Aman B. Patel, and Joshua B. Bederson -- Surgical treatment of anterior circulation aneurysms / G. Edward Vates and Art Day Shankar -- Endovascular treatment of anterior circulation aneurysms / Reza Jahan, Gary Duckwiler, and Fernando Vinuela -- Surgical considerations of posterior circulation aneurysms / Howard A. Riina and Robert F. Spetzler -- Endovascular treatment of posterior circulation aneurysms / Italo Linfante, Cole Blease Graham, III, and Ajay K. Wakhloo -- Treatment of cerebral arteriovenous malformations / Andrew Jea, Mustafa K. Bakaya, and Roberto C. Heros -- Endovascular treatment of arteriovenous malformations / Gary M. Nesbit [and others] -- Radiosurgical treatment of arteriovenous malformations / Douglas Kondziolka, L. Dade Lunsford, and John C. Flickinger -- Surgical treatment of intracranial dural arteriovenous fistulas / Y. Jonathan Zhang [and others]. Endovascular management of dural arteriovenous fistulas / Yasunari Niimi [and others] -- Surgical management of extracranial vascular occlusive disease / Brian E. Snell, Robert J. Wienecke, and Christopher M. Loftus -- Endovascular revascularization of carotid artery disease / Philip M. Meyers, Sean D. Lavine, and Randall T. Higashida -- Diagnosis and medical and endovascular management of intracranial atherosclerotic disease / Hunaldo Villalobos, Alan S. Boulos, and Lee R. Guterman -- The case for microsurgery in the treatment of cavernous malformations / Mustafa K. Bakaya, Andrew Jea, and Jacques J. Morcos -- Observation of cavernous malformations / Darryl Gress and Vineeta Singh -- The departmental model for practice in neurovascular disease / Christopher S. Ogilvy [and others] -- The institutional model for practice: an interventional neurovascular program within an academic neurological surgery department / T.C. Origitano, Harish Shownkeen, Mary Fitzgerald, and Trisha Cassidy -- The neurovascular center model for practice / Edwin J. Cunningham and Marc R. Mayberg -- Regionalization of neurovascular medicine / E. Sander Connolly, Jr., Mitchell F. Berman, and Robert A. Solomon -- Resolving controversy and uncertainty with evidence / S. Claiborne Johnston -- Developing the neurovascular surgical specialists of the future / Charles Y. Liu [and others] -- Developing the endovascular and neurovascular specialists of the future / Cameron G. McDougall.
  • In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection, and management of CMD in their everyday activity.
  • General concepts of blood vessel formation and remodeling -- Prenatal coronary Morphogenesis -- Postnatal coronary morphogenesis and growth -- Sturcture function of the coronary hierarchy -- Historical perspectives -- Coronary anomalies -- Aging -- Adaptations to exercise training -- Hypoxia -- Myocardial ischemia and infarction -- Cardiac hypertrophy -- Therapy for the coronary circulation.
  • Goals, design, and implementation of critical pathways in cardiovascular medicine / Christopher P. Cannon and Patrick O'Gara -- Part I. -- Prehospital critical pathways -- Prehospital fibrinolysis / Freek W.A. Verheught -- Regional transfer programs for primary PCI / David M. Larson and Timothy D. Henry -- Public access defibrillation / Joseph P. Ornato -- Part II. -- Critical pathways in the emergency department -- Non-ST elevation ACS in the emergency department / Richard J. Ryan, Christopher P. Cannon, and W. Brian Gibler -- Thrombolysis for ST-elevation mi in the emergency department / Joshua M. Kosowsky -- Heart failure in the emergency department / W. Frank Peacock -- Atrial fibrillation in the emergency department / Ray Bahr -- Stroke and TIA / Lee Schwamm -- The Role of exercise testing in chest pain units: evolution, application, results / Ezra A. Amsterdam, Deborah B. Diercks, and Samuel D. Turnipseed -- Part III -- Critical pathways in the hospital -- Critical pathway for non-ST elevation ACS / Christopher P. Cannon and Patrick T. O'Gara -- Primary PCI / Amr E. Abbas and Cindy L. Grines -- Primary PCI at community hospitals without on-site cardiac surgery / Nancy Sinclair and Thomas P. Wharton, Jr. -- Approach to the patient with complicated myocardial infarction / Richard C. Becker -- Cardiac catheterization and percuraneous coronary intervention / Jeffrey J. Popma -- Pathways for coronary artery bypass surgery / Rashid M. Ahmad, Frances Wadlington, Tiffany Street, James P. Greelish, Jorge M. Balaguer, and John G. Byrne -- Acute aortic syndromes / Piotr Sobieszcyk and Patrick O'Gara -- Intensive management of hyperglycemia in ACS / Vera T. Fajtova -- Management of atrial fibrillation and atrial flutter / Eyal Herzog and Jonathan S. Steinberg -- Heart failure / Greg Fonarow -- Device therapy in patients with heart failure / Peter J. Zimetbaum and Eli V. Gelfand -- Venous thromboembolism / Samuel Z. Goldhaber -- Part IV. -- Critical pathways in the outpatient setting / -- Hyperlipidemia / Frederick F. Samaha and Daniel J. Rader -- Diabetes and metabolic syndrome / Emily Deborah Szmuilowicz and Merri Pendergrass -- Hypertension / Michael A. Weber -- Smoking cessation / Beth C. Bock -- Secondary prevention overview / Sidney Smith -- Overview of the AHA "get with the guidelines" programs / Yuling Hong, Kenneth A. LaBresh -- Cardiac rehabilitation in the post myocardial infarction patient / Daniel E. Forman.
  • Principles of computed tomographic angiography -- Principles of magnetic resonance angiography -- Conventional angiography in the noninvasive era -- Contrast medium administration in computed tomographic angiography -- Contrast medium administration in magnetic resonance angiography -- Postprocessing and data analysis -- Atherosclerosis : epidemiology and pathology -- Atherosclerosis : in vivo characterization -- Thromboembolism -- Vasculitides and connective tissue disorders -- Cerebral arteries and veins -- Cervical vasculature -- Quantifying coronary artery calcium -- Coronary arteries -- Thoracic vascular anomalies -- Pulmonary vasculature -- Thoracic aorta -- Abdominal aorta -- Mesenteric vasculature -- Renal vasculature -- Lower extremities vasculature -- Upper extremities vasculature -- Pediatric techniques and vascular anomalies -- Venous system.
  • Hereditary angioedema in 2011 / Marco Cicardi -- Hereditary angioedema : diagnosis and pathogenic mechanisms / Allen P. Kaplan -- Current options for the acute treatment and prophylaxis of hereditary angioedema / Laraib Tabba & Timothy J. Craig -- Novel C1 inhibitors for hereditary angioedema / Henriette Farkas & Lilian Varga -- New drug targets and future direction : ecallantide / Jonathan A. Bernstein -- New drug targets and future direction : icatibant / Konrad Bork -- Index.
  • Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.
  • In Diabetes and Peripheral Vascular Disease, a panel of distinguished leaders in the field of medicine, podiatry, and vascular and endovascular therapy assimilate the latest literature on these issues and others for an in-depth review of the management of peripheral vascular disease. Providing an overview of the management of diabetes and diabetic foot changes as well as providing a view of cutting-edge and emerging topics in optimization of arterial status, this important title addresses pathophysiology, anatomy, diagnosis and management of diabetic peripheral vascular disease, emphasizing a multi-disciplinary approach. The first chapter of the book provides an overview of this complex disease process and discusses the teamwork required for optimal management. The chapters continue with the basic pathophysiology of diabetic atherosclerosis and a contemporary review of the management of diabetes. The genesis of diabetic foot ulceration and prevention and management strategies is covered, as is the effects of neuropathy and microvascular changes in the diabetic foot. In addition, Diabetes and Peripheral Vascular Disease covers the microbiology of diabetic foot infections, the role of endovascular interventions and vascular surgery as well as the management of the complications of these procedures, the process of amputation for those patients who have progressed beyond a limb salvage situation, and the effects of diabetes on the cerebrovascular system as well as its implications in patients with aortoiliac disease. An invaluable addition to the literature on diabetes and peripheral vascular disease, the book will be of great interest internists, family practitioners, surgeons, podiatrists, wound care specialists, and vascular specialists. Students, residents, and fellows in surgical and medical specialties should also find this book of significant value and interest.
  • Endovascular repair of dialysis fistulas and grafts: strengths and weaknesses -- Role of the nephrologist, interventional radiologist, and vascular access in the treatment of end-Stage renal disease -- Access creation strategy -- Natural history of vascular access -- Radiological anatomy and preoperative imaging of upper limb vessels -- Indications and imaging modalities in dialysis access -- Psychological and clinical issues -- Patient preparation prior to angiography and endovascular interventions -- Angiography (Fistulography) -- Dilation and stent placement -- Hand ischemia -- Treatment of thrombosed accesses -- Therapeutic occlusion of dysfunctional accesses -- Complications during and after vascular access endovascular procedures -- Vascular access intervention outcomes.
  • This practical book covers the basic principles and practice of dialysis access management, a crucial part of the care of patients undergoing hemodialysis. It has been written in an easy-to-read, step-by-step format to help facilitate learning and understanding of the procedures, and has been supplemented with numerous operative photographs and diagrams demonstrating the commonly performed dialysis access exams, interventions, procedures and surgeries. Dialysis Access Management is an essential text for residents, fellows, and physicians who are learning or practicing in dialysis and/or dialysis access management, especially in the fields of nephrology, radiology, surgery, and vascular medicine.
  • Drug-eluting stents 2012
    Future Med
    Drug-eluting stents / Imad Sheiban & Fabrizio D'Ascenzo -- Drug-eluting stents : overview and indications / Fabrizio D'Ascenzo & Imad Sheiban -- Coronary artery stents : approved first-generation drug-eluting stents / Jason R. Foerst, Frank Gruenheck, Malte Kelm & Marc Vorpahl -- Approved drug-eluting stents : second generation / Giampaolo Niccoli & Gregory A. Sgueglia -- Drug-eluting stents in development / Joanne Shannon & Azeem Latib -- Current guidelines for the use of drug-eluting stents / Gill Louise Buchanan & Alaide Chieffo -- Index.
  • [Beta]-blocking agents / Lionel H. Opie -- Nitrates and newer antianginals / Lionel H. Opie, John D. Horowitz -- Calcium channel blockers / Lionel H. Opie -- Diuretics / Lionel H. Opie, Ronald G. Victor, Norman M. Kaplan -- Inhibitors of the renin-angiotensin-aldosterone system / Lionel H. Opie, Marc A. Pfeffer -- Heart failure / John R. Teerlink, Karen Sliwa, Lionel H. Opie -- Antihypertensive therapies / Lional H. Opie ... [et al.] -- Antiarrhythmic drugs and strategies / Stanley Nattel, Bernard J. Gersh, Lionel H. Opie -- Antithrombotic agents : platelet inhibitors, acute anticoagulants, fibrinolytics, and chronic anticoagulants / Keith A.A. Fox ... [et al.] -- Lipid-modifying and antiatherosclerotic drugs / Antonio M. Gotto Jr., Lionel H. Opie -- Metabolic syndrome, hyperglycemia, and type-2 diabetes / Lionel H. Opie, Juris Meier, John M. Miles -- Which therapy for which condition? / Bernard J. Gersh, Lionel H. Opie.
  • This book describes in detail the use of duplex ultrasound for exploration of the superficial veins and their pathology. It has a practical orientation, presenting numerous clinical situations and explaining how to identify the different sources of reflux, specially in the groin. The investigation of pathology of the saphenous trunks, perforators, and side branches is described in detail. As duplex ultrasound plays an important role during various venous surgical procedures, its application pre-, intra-, and postoperatively is presented. Furthermore, the sonographic appearances of thrombotic pathology of superficial and deep veins, edema, and other conditions that may be observed while exploring the veins are fully described. The book is based on the authors{u2019} extensive clinical experience and is intended to assist fellow practitioners who want to learn more about the technique. It includes a wealth of informative images with the aim of covering every potential situation.
  • Embolisation 2012
  • Embolization 2014
    Innovations in catheterization techniques and embolization agents have considerably contributed to the development of endovascular occlusion techniques in arterial and venous trunks as much as distal parenchymal capillar beds. Mini invasive therapies, endovascular embolization and chemo-embolization now constitute valuable therapeutic alternatives in various fields: on a purely palliative or on a curative basis in oncology, but also in traumatology, functional diseases, and for the treatment of benign tumors, or when dealing with post-operative complications. As in-depth and detailed descriptions of these techniques are all ready available in specialized books, our ambition is to provide a basic handbook for the young vascular radiologists in training and a checklist for the more experienced interventional radiologists, by providing for each of the constantly increasing indications a synthetic approach of the technique and its expected results. The first part of this book relates to the tool box (the materials) and the procedure techniques as well as the physiopathological requirements for carrying out embolization; the second part is an analytical description of the main situations and anatomo-clinical strategies. This handy book should to be a valuable memory aid for clinicians and interventional radiologists, readily available in the multidisciplinary staff rooms and in angiography suites.
  • Cardiovascular (CV) disease is the leading cause of death worldwide. While death rates from many acute CV illnesses have declined in developing countries, a substantial proportion of individuals with CV disease ultimately die from CV causes. As the population ages, the global burden of CV disease will continue to rise. Until recently, the focus of clinicians has been on saving lives and deferring death. Over the past decade there has been growing recognition of the importance of palliative care and end of life care in CV disease. While palliative and supportive care should be provided throughout the course of serious and life-shortening illnesses, this book focuses on issues that clinicians encounter in end-of-life care. This book provides guidance to clinicians working across the breadth of care settings, in chronic progressive disease as well as sudden arrhythmic death andwith advanced technologies. End-of-Life Care in Cardiovascular Disease is designed to assist clinicians, nurses, and other healthcare providers in addressing end of life care for patients with CV disease in a variety of common clinical scenarios. Each chapter is written by expert clinicians and researchers, and concisely reviews current knowledge and recommendations for providing patient- and family-centered end-of-life care.
  • Part I: Basic MRI Principles.- A Brief History of Magnetic Resonance Imaging -- Fundamentals of Magnetic Resonance Imaging -- The Relaxation Concept in MRI -- MRI Pulse Sequences -- MR Imaging Parameters and Options -- Part II: MR Safety, Patient Positioning, Protocol Design, Graphical Prescription and MR Applications for Anatomical Regions.- Introduction to Safe Clinical Scanning -- Central Nervous System: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Musculoskeletal Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Body Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Cardiovascular Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Breast Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions.
  • Endovascular neurosurgery is a recently introduced but rapidly evolving medical field, which uses minimally invasive interventions to treat major life-threatening vascular lesions of the Central Nervous System. Although its history counts less than 15 years of worldwide acceptance, it has rapidly displaced the traditional open neurosurgical techniques, being nowadays the first treatment choice for brain aneurysms and vascular malformations. Thus, the experience of each neuroendovascular center and performer is invaluable, offering the base for learning and teaching the new generation of interventionalists as well as for the evolvement of the method itself. This book presents the basic principles of endovascular neurosurgery starting from clinical cases. Through this close-to-clinical-reality-process, the reader will be able to more thoroughly understand the pathophysiology of the brain and spine vascular lesions as well as the decision-making strategy, related to the indications, endovascular methods and results, finding suggestions and solutions to his/her clinical questions and problems. Besides chapters devoted to CNS vascular embryology and anatomy, clinical cases organized in groups based on the treated lesions are introduced: ruptured and unruptured cerebral aneurysms of the anterior and posterior circulation, side-wall and bifurcation aneurysms, arteriovenous malformations (AVM), dural arteriovenous fistulae (dAVF), arterial stenosis and angioplasty as well as spinal vascular lesions. A separate chapter is devoted to the organization and necessary equipment of the angio room and the department offering neuroendovascular service. This volume will be of interest to neurosurgeons, interventional neuroradiologists, vascular surgeons, neurologists and ICU physicians as well as health care providers who are involved in the diagnosis and management of the vascular lesions of the brain and spine.
  • In the 4th edition, Drs. Wesley S. Moore, Samuel S. Ahn, and a host of experts guide you through the latest developments in this innovative field. New procedures and special features, such as key points and case reviews, help illustrate effective patient care, and new topics such as endoscopic management of aneurismal disease and traumatic injuries review with you the latest endovascular surgical techniques. Broaden your surgical skills with new chapters on endoscopic management of aneurismal disease and traumatic injuries, and review a valuable new section covering the TIPS Procedure for Portal Hypertension, Anesthetic Management for Endovascular Procedures, the Use of Coil Embolization in Endovascular Surgery, and more. An in-depth, core reference on the best practices and techniques in endovascular surgery. Perfect for both the training vascular surgeon who needs a comprehensive view of endovascular surgery as well as a refresher on current techniques and optimal outcomes for the practitioner.
  • This concise guide to the often overlooked association between erectile dysfunction and hypertension/cardiovascular disease covers a wide range of aspects of importance to the clinician. It examines the impact of antihypertensive drug therapy on erectile function and explains how the management of erectile dysfunction in hypertensive patients depends on a variety of factors. Different treatment approaches are described, including lifestyle modification, PDE-5 inhibitors and other novel agents, and behavioral therapy, and helpful therapeutic algorithms are presented. A further focus of the book is the potential role of erectile dysfunction as an early diagnostic indicator of asymptomatic coronary artery disease and a prognostic marker for cardiovascular events. In addition, key background information is supplied on epidemiology and pathophysiology, and the significance of erectile dysfunction in different patient groups, such as the elderly and those with chronic kidney disease, is examined. Erectile dysfunction is a major public health problem affecting more than ten percent of the general male population and is now considered to be predominantly of vascular origin. This book will be informative and of practical value for all practitioners responsible for caring for the very many patients who experience erectile dysfunction in the setting of hypertension and cardiovascular disease.
  • Schematic presentation of the hemostatic system / Nils Egberg -- Proposals for sampling instructions / Margareta Blombäck and Nils Egberg -- Laboratory investigations / Jovan P. Antovic, Liselotte Onelöv, and Nils Egberg -- Hereditary bleeding disorders / Margareta Holmström and Lars-Göran Lundberg -- Critical bleeding / Maria Bruzelius, Anna Ågren, and Hans Johnsson -- Investigation of increased bleeding tendency / Margareta Holmström and Lars Göran Lundberg -- Venous thrombosis and pulmonary embolism / Anders Carlsson -- Investigations of thromboembolic tendency / Margareta Holmström -- Heart disease / Håkan Wallen and Rickard Linder -- Antiplatelet drug therapy and reversal of its effects / Håkan Wallen, Hans Johnsson, and Bo-Michael Bellander -- New oral anticoagulants : focus on currently approved oral factor Xa and thombin inhibitors / Rickard E. Malmström and Hans Johnsson -- Stroke and transient ischemic attack / Nils Wahlgren and Mia von Euler -- Peripheral artery surgery / Jesper Swedenborg -- Hemostasis in obstetrics and gynecology / Katarina Bremme -- Hemostasis in children / Susanna Ranta and Pia Petrini -- Emergency conditions associated with coagulation : DIC, HIT, and TTP/HUS / Jovan P. Antovic and Margareta Holmström.
  • This title is directed primarily towards health care professionals outside of the United States. This book has been prepared by professionals working in the UK. It covers the basic principles and practice of interventional cardiology, vascular and non-vascular, written specifically for the general cardiologist. Designed to facilitate easy access to key information, it contains numerous line illustrations, diagrams, graphs, and charts. The entire spectrum of interventional cardiology is covered in an easy-to-read format. In this new edition are fifteen new chapters written by experts from around the world. The excellent appendix of trials in interventional cardiology has been fully updated making this the best available source on how to apply trials to clinical practice. Includes editors and contributors from the US and Europe for a truly international perspective. Begins each chapter with 6-10 key points written in bullet format that summarize important concepts in the chapter, making reference a snap.
  • Diagnosis and imaging -- Surgical and endovascular technique and tools -- Peripheral arterial thrombosis/emboli -- Compartment syndrome -- Diabetic foot infection -- PAD and claudication -- Critical limb ischemia -- Lower extremity amputations -- Deep venous thrombosis -- Superficial thrombophlebitis -- Chronic venous insufficiency -- Varicose veins -- Inferior vena cava filters -- Vascular injuries in the neck -- Vascular injuries in the abdomen -- Extremity vascular injuries -- Temporary venous catheters -- Arteriovenous hemodialysis access -- Access complications -- Arterial occlusive disease: carotid, mesenteric, renal -- Aortic pathology: AAA, dissection, traumatic transection -- Non-atherosclerotic vascular disease: vasculitis, popliteal entrapment, hypercoaguable -- Surgical and endovascular complications: infection, hemorrhage.
  • Part of the popular Case Review series, this outstanding Board review book presents over 200 unknown cases--complete with over 350 state-of-the-art images, questions, answers, commentary, references, and more--to enhance your imaging interpretation skills in general and vascular ultrasound. Discussions incorporate the most recent knowledge from the literature in this field, providing an excellent review for both residents and practitioners. Follows the format of the Boards, and offers case studies similar to those likely to be found on exams, for a realistic preparation for the test-taking experience. Presents cases in 3 overall categories--from least to most difficult--to build your skills in a cumulative way. Offers cross references to Ultrasound: The Requisites, 2nd Edition, so it's easy to find in-depth information on any subject.
  • pt. 1. Genes and the heart -- pt. 2. Development and gender -- pt. 3. Mitochondrial diseases -- pt. 4. Ischemic heart disease -- pt. 5. Hypertension and arrhythmias -- pt. 6. Hypertrophy and failure.
  • Overview of Venous Thromboembolism -- Risk Factors for Venous Thromboembolism -- Pathophysiology of Deep Vein Thrombosis and Pulmonary Embolism -- Diagnosis of Deep Vein Thrombosis -- Diagnosis of Pulmonary Embolism -- Risk Stratification and Prognosis -- Advanced Therapy for Venous Thromboembolism -- Anticoagulation for Venous Thromboembolism -- Long-term Management of Venous Thromboembolism -- Prevention of Venous Thromboembolism .
  • Fully revised and updated, the Handbook serves as a practical guide to endovascular methods and as a concise reference for neurovascular anatomy and published data about cerebrovascular disease from a neurointerventionalist's perspective. Divided into three parts, the book covers:* Fundamentals of neurovascular anatomy and basic angiographic techniques; * Interventional Techniques and endovascular methods, along with useful device information and tips and tricks for daily practice; * Specific Disease States, with essential clinical information about commonly encountered conditions.New features in the 2nd Edition include:* Global Gems that illuminate aspects of the field outside the United States;* Angio-anatomic and angio-pathologic image correlates;* Newly released clinical study results influencing neurointerventional practice;* Information on emerging technologies in this rapidly advancing field.The Handbook is a vital resource for all clinicians involved in neurointerventional practice, including radiologists, neurosurgeons, neurologists, cardiologists, and vascular surgeons.
  • Handbook of Endovascular Interventions presents a step-wise approach to the techniques of peripheral vascular interventions. Covering interventions in all major organ systems, this concise and comprehensive resource provides the rationale on why these approaches have been adopted by most practicing vascular interventionalists. This volume also presents key information on intervention techniques and pitfalls, complications and their management, surgical management options, as well as landmark papers on the topic. Unique to this book is the inclusion of sections building an endovascular suite, and coding as well as international training paradigms across the globe.Authored by international experts from around the globe, Handbook of Endovascular Interventions is a true how-to book for the busy interventionalist.
  • Handbook of neuroendovascular surgery 2012
    Thieme eNeurosurgery
    "The evolution of vascular neurosurgery has continued and now provides a new set of tools to treat hemorrhagic and ischemic disease. Clearly, this evolution is becoming mainstream in neurosurgical training and adds to the body of knowledge that currently exists within traditional neurosurgical education."--Excerpt from notes provided by publisher.
  • Systematic clinical assessment -- Historical evaluation of key signs and symptoms -- General medical review -- General examination -- Neurologic examination -- Approach to the comatose patient -- Laboratory evaluation -- Differential diagnosis made easy: general approach -- Temporal profile of ischemic cerebrovascular diseases -- Telephone interview and triage -- Management of acute stroke in critically ill patients -- Transient ischemic attack and minor cerebral infarction: general evaluation and treatment -- Major cerebral infarction: general evaluation and treatment -- Subarachnoid hemorrhage: general evaluation and treatment -- Intracerebral hemorrhage: general evaluation and treatment -- Four major categories of ischemic cerebrovascular disease: identification and treatment -- Five major categories of hemorrhagic disease: treatment of specific underlying mechanisms -- Cerebral venous thrombosis -- Other cerebrovascular syndromes -- Vascular disease of the spinal cord -- Cerebrovascular disease in children and young adults -- Cerebrovascular disease in pregnant patients -- Cerebrovascular disease genetics -- Modifiable lifestyle and environmental factors -- Asymptomatic carotid and vertebral stenosis -- Hypertension -- Dyslipidemia -- Other host factors -- Unruptured intracranial aneurysms -- Unruptured intracranial vascular malformations -- Hematologic disease -- Carotid or vertebral artery occlusive disease -- Transient ischemic attack -- Cerebral infarction -- Intracerebral hemorrhage -- Subarachnoid hemorrhage -- Physical therapy -- Speech therapy -- Other chronic complications of stroke -- Family and patient education.
  • Anatomy of cerebral veins and sinuses -- Epidemiology of cerebral vein and sinus thrombosis / Agnelli, G., Verso, M. -- Risk factors of cerebral vein and sinus thrombosis / de Freitas, G.R., Bogousslavsky, J. -- Thrombophilia and cerebral vein thrombosis / Iorio, A. ... [et al.] -- Clinical presentations of cerebral vein and sinus thrombosis / Paciaroni, M., Palmerini, F., Bogousslavsky, J. -- Headache and cerebral vein and sinus thrombosis / Alberti, A., Venti, M., Biagini, S. -- Radiological diagnosis of cerebral venous thrombosis / Selim, M., Caplan, L.R. -- Role of ultrasound in diagnosis and management of cerebral vein and sinus thrombosis / Stolz, E.P. -- Cerebral venous thrombosis in newborns, infants and children / Yager, J.Y. ... [et al.] -- Treatment of cerebral venous and sinus thrombosis / Masuhr, F. -- Interventional neuroradiology in the treatment of cerebral venous thrombosis / Caso, V., Billeci, A.M.R., Leys, D. -- Complications of cerebral vein and sinus thrombosis / Ferro, J.M., Canhao, P. -- Long-term prognosis of cerebral vein and sinus thrombosis / Lindgren, A.
  • Physical and technical principles / Evans, D.H. -- Arterial wall imaging / Devuyst, G., Piechowski-Jóźwiak, B., Bogousslavsky, J. -- Endothelial function testing / Csiba, L. -- Atherosclerotic carotid stenosis and occlusion / Sitzer, M. -- Ultrasound diagnostics of the vertebrobasilar system / von Büdingen, H.-C., Staudacher, T., von Büdingen, H.J. -- Ultrasound diagnosis of cervical artery dissection / Benninger, D.H., Baumgartner, R.W. -- Intracranial dural arteriovenous and carotid-cavernous fistulae and paragangliomas / Gandjour, J., Baumgartner, R.W. -- Takayasu and temporal arteritis / Schmidt, W.A. -- Transcranial insonation / Baumgartner, R.W. -- Intracranial stenoses and occlusions, and circle of Willis collaterals / Baumgartner, R.W. -- Acute stroke: perfusion imaging / Seidel, G., Meyer-Wiethe, K. -- Sonothrombolysis: experimental evidence / Daffertshofer, M., Hennerici, M. -- Acute stroke: therapeutic transcranial Doppler sonography / Mikulik, R., Alexandrov, A.V. -- Acute stroke: therapeutic transcranial color duplex sonography / Eggers, J. -- Cerebral aneurysms and arteriovenous malformations / Klötzsch, C., Harrer, J.U. -- Cerebral veins and sinuses / Stolz, E. -- Detection of microembolic signals with transcranial Doppler ultrasound / Georgiadis, D., Siebler, M. -- Contrast-enhanced transcranial Doppler ultrasound for diagnosis of patent foramen ovale / Nedeltchev, K., Mattle, H.P. -- Cerebral autoregulation and vasomotor reactivity / Aaslid, R. -- Cerebral circulation monitoring in carotid endarterectomy and carotid artery stenting / Ackerstaff, R.G.A. -- Syncope / Nirkko, A.C., Baumgartner, R.W. -- Functional transcranial Doppler sonography / Lohmann, H., Ringelstein, E.B., Knecht, S. -- Future developments in neurovascular ultrasound / Meairs, S., Hennerici, M.
  • The genesis of health : evolution of the concept of health-related quality of life -- Quality of life in hypertensive patients -- Quality of life in patients with coronary artery disease -- Quality of life in patients after coronary interventional treatment -- Quality of life in patients with chronic heart failure -- Quality of life in patients with cardiac rhythm disturbances -- Quality of life in patients with implantable cardiac devices -- Quality of life after stroke.
  • What drives the circulation? In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena. A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output. This new model arises from accumulated clinical and experimental evidence. The heart, rather than being an organ of blood propulsion, assumes a secondary role and generates pressure by impeding the flow of blood. This is supported by examples from the fields of early embryonic circulation, comparative phylogeny, functional morphology, exercise physiology and a range of clinical scenarios. The Heart and Circulation: An Integrative Model offers a paradigm shift in the understanding of circulatory phenomena. It will become a valuable resource for all those clinicians, researchers, educators and students who, having been confronted with the paradox of the circulation, are looking for a broader interpretation.
  • I. Introduction and General Overview -- 1.Vascular Embryology -- 2. Molecular and Genetic Aspects in Infantile Hemangiomas and Vascular Malformations -- 3. Introduction and Background Notes -- 4. Clotting Problems -- II. Hemangiomas and Vascular Tumors -- 5. Hemangiomas in Infancy: Epidemiology -- 6. Classification of Infantile Hemangiomas and Other Congenital Vascular Tumors -- 7. Clinical Picture -- 8. Diagnostics of Infantile Hemangiomas Including Visceral Hemangioma -- 9. Principles of Treatment -- 10. Propanolol and Betablockers in Medical Treatment of Infantile Hemangiomas -- 11. Other Medical Treatments of Infantile Hemangiomas and Other Vascular Tumors -- 12. Laser Treatment of Infantile Hemangiomas -- 13. Surgical Treatment -- 14. Treatment by Embolization -- 15. Treatment of Infantile Laparoscopic Rectal Anterior Resection in Head and Neck -- 16. Treatment of Visceral Infantile Hemangiomas -- 17. Treatment of Genital Infantile Hemangiomas -- 18. Management of Syndromes Related to Infantile Hemangiomas -- III. Vascular Malformations -- 19. Epidemiology -- 20. Histology in Vascular Malformations -- 21. Classifications -- 22. Principles of Diagnostics -- 23. Clinical Aspects in Vascular Malformations -- 24. Dermatologic Aspects in Vascular Malformations -- 25. Ultrasound Diagnostics -- 26. Role of MR and CT in Diagnostics -- 27. Nuclear Medicine -- 28. Angiography and Phlebography -- 29. Principles of Treatment -- 30. Surgical Techniques and Tactics in Vascular Malformations -- 31. Interventional Treatment in AVM -- 32. Principles and Technical Skills in Ethanol Treatment of Vascular Malformations -- 33. Sclerosis in Vascular Malformations -- 34. Laser Treatment of Vascular Malformations -- 35. Possibilities and Limits of Medical Treatment -- 36. Approach to Syndromes in Vascular Malformations -- IV. Treatment of Problems According to Specific Localizations -- 37. Introduction -- 38. Head and Neck Malformations: Surgical Treatment -- 39. Head and Neck Malformations: Sclerosis Treatment -- 40. Treatment of Upper Airway Involvement -- 41. Treatment of Intraorbital Vascular Malformations -- 42. Orthopedic Problems, -- 43. Treatment of Vascular Malformations of the Hand -- 44. Thorax Wall -- 45. Visceral Vascular Malformations -- 46. Pelvic Malformation -- 47. Vascular Malformations of the Limbs: Treatment of Arterio-Venous and Venous Malformations -- 48. Lymphatic Vascular Malformations of the Limbs: Treatment of Extratruncular Malformations -- 49. Lymphatic Vascular Malformations of the Limbs: Conservative Treatment of Truncular Malformations -- 50. Lymphatic Truncular Malformations of the Limbs: Surgical Treatment -- 51. Thoracic Duct Dysplasia and Chylous Reflux -- 52. Conclusions -- Subject Index.
  • 2012 ClinicalKey
    Neonatal hemodynamics -- Principles of developmental cardiovascular physiology and pathophysiology -- Principles of developmental cardiovascular physiology and pathophysiology -- Autoregulation of vital and nonvital organ blood flow in the preterm and term neonate -- Definition of normal blood pressure range: the elusive target -- Diagnosis of neonatal shock: methods and their clinical applications -- Methods to assess systemic and organ blood flow in the neonate -- Functional echocardiography in the neonatal intensive care unit -- Assessment of cardiac output in neonates: techniques using the Fick principle, pulse wave form analysis, and electrical impedance -- Near-infrared spectroscopy and its use for the assessment of tissue perfusion in the neonate -- Clinical applications of near-infrared spectroscopy in neonates -- Advanced magnetic neuroimaging techniques in the neonate with a focus on hemodynamic-related brain injury -- Cardiovascular magnetic resonance in the study of neonatal hemodynamics -- Assessment of the microcirculation in the neonate -- Clinical presentations and relevance of neonatal shock -- Clinical presentations of neonatal shock: the very low birth-weight neonate during the first postnatal day -- Very low birth weight neonate with hemodynamically significant ductus arteriosus during the first postnatal week -- Preterm neonate with cardiovascular and adrenal insufficiency -- Shock in the surgical neonate -- Hemodynamics and brain injury in the preterm neonate -- Fetal and neonatal cardiology -- Embryonic and fetal development -- Genetics of fetal and neonatal cardiovascular disease -- Human cardiac development in the first trimester -- Reappraisal of normal and abnormal cardiac development -- Fetal and neonatal cardiology -- New concepts for training the pediatric cardiology workforce of the future -- Current role of fetal echocardiography -- Clinical evaluation of cardiovascular unction in the human fetus -- Cardiac surgery in the neonate with congenital heart disease -- Regional blood flow monitoring in the perioperative period -- Mechanical pump support and cardiac transplant in the neonate -- Catheter-based therapy in the neonate with congenital heart disease -- Hybrid management techniques in the treatment of the neonate with congenital heart disease.
  • 2013 Ovid
    Introduction to the field of hemostasis and thrombosis -- Basic principles of hemostasis and thrombosis. Coagulation and fibrinolysis ; Platelet biology ; Vascular biology -- Disorders of coagulation, platelets, and vessel wall. Bleeding disorders of coagulation and fibrinolysis ; Acquired and inherited platelet disorders ; Primary disorders of blood vessels ; Therapy of bleeding disorders -- Thrombotic disorders. Venous thrombotic disorders ; Arterial thrombotic disorders ; Complex thrombotic disorders ; Therapeutic agents -- Hemostatic and thrombotic disorders associated with systemic conditions.
  • Stroke is a leading cause of death and disability throughout the world. Intravenous lytics and endovascular stroke treatment were demonstrated to be highly beneficial in clinical trials and in achieving net cost savings. However, time is of the essence in the management of stroke as for every minute that stroke is left untreated, an estimated 1.9 million neurons are destroyed. An optimized stroke pathway can dramatically impact patient outcome. Every medical service will differ.This book offers a concise and practical guide on how to set up and efficiently run an acute stroke service tailored to the needs of the individual center as a provider of primary, secondary, or tertiary care. It documents the essential knowledge on current imaging and treatment options and offers guidance in organizing a site-specific stroke pathway that will ensure the quickest possible provision of treatment, thereby optimizing benefit to the patient and maximizing cost-effectiveness. The authors played an integral part in the development and operation of one of Europe's most successful early stroke centers and also have experience of the factors that can undermine the creation of world-class stroke units. On this basis, they address the key aspects of the stroke pathway and explain how organizing this can reduce the number of severe outcomes by ensuring that appropriate steps are taken during the early moments after stroke when intervention can make a profound difference. The challenging, multidisciplinary nature of care is emphasized, and this handbook will be an invaluable source for every member of the stroke team, including doctors, nurses, stroke coordinators, emergency and rehabilitation providers as well as hospital administrators.
  • Hypertension 2013
    Future Med
    Update on hypertension, its genetics, epidemiology, mechanisms, clinical approaches and novel treatments / Ernesto L. Schiffrin & Rhian M. Touyz -- Definition & diagnosis of hypertension / Ernesto L. Schiffrin -- Epidemiology of hypertension / Stanley S. Franklin & Nathan D. Wong -- Genetics of hypertension / Christian Delles -- Hemodynamics / Joseph L. Izzo Jr. -- Role of the kidney in hypertension / John E. Hall, Jussara M. do Carmo, Alexandre A. da Silva, Zhen Wang & Michael E. Hall -- Renin-angiotensin-aldosterone system : new concepts / Aurelie Nguyen Dinh Cat, Augusto C. Montezano & Rhian M. Touyz -- Endothelin system : roles in hypertension / Yohann Rautureau & Ernesto L. Schiffrin -- CNS pathways contributing to sympathetic hyperactivity and hypertension / Frans H.H. Leenen -- Hypertensive vascular disease / Carmine Savoia & Ernesto L. Schiffrin -- Hypertensive heart disease / Javier Díez -- Classification and diagnosis of hypertension / Clive Rosendorff -- Hypertension and cardiovascular risk / Maria Czarina Acelajado & Suzanne Oparil -- Lifestyle modifications / Franz Messerli & Tiberio Frisoli -- Antihypertensive agents / Domenic A. Sica -- Treatment of hypertension / Ross D. Feldman -- Clinical practice guidelines / Sheldon W. Tobe, Diane Hua & Patrick Twohig -- Resistant hypertension / David A. Calhoun -- Index.
  • 2008 Ovid
  • Hypertension has become a major public health hazard not only in industrialized nations, but also in emerging economies. Early detection combined with effective treatment is imperative to reduce the risk of patients developing premature cardiovascular disease and accelerated atherosclerosis. A clear, concise resource, Hypertension: A Clinical Guide is of practical value to primary care doctors around the world who treat patients with hypertension every day. The book explores both fundamental and practical aspects, including epidemiology, risk, treatment, and secondary causes. After discussing methods of diagnosis and evaluation, the book explores a range of pharmacological and non-pharmacological treatment options. Specialized chapters address topics such as hypertensive emergencies, hypertension in pregnancy and renal disease, renovascular hypertension, primary hyperaldosteronism, and pheochromocytoma. Illustrated with photos and tables, this volume is essential reading for physicians, nurses, and allied health professionals with an interest in hypertension whether in primary care, in hospitals, or in training.
  • Blood pressure: definition, diagnosis, and management -- The link between hypertension and stroke: summary of observational epidemiological studies -- Blood pressure control and primary prevention of stroke: summary of clinical trial data -- Mechanisms underlying essential hypertension: neurogenic and nonneurogenic contributors -- Pathophysiology and mechanisms whereby hypertension may cause stroke -- Cardiovascular risk assessment and summary of guidelines for the management of hypertension -- Acute blood pressure management after ischemic stroke -- Hypertensive encephalopathy and acute blood pressure management after hemorrhagic stroke -- Recurrent stroke prevention I: diuretic and angiotensin-converting enzyme inhibitors (ACEIs): the PROGRESS trial -- Recurrent stroke prevention II: angiotensin receptor blockers: the LIFE, MOSES, PRoFESS, and other trials -- A practical guide to recurrent stroke prevention -- Vascular cognitive impairment and Alzheimer disease: are these disorders linked to hypertension and other cardiovascular risk factors? -- Cerebral small vessel disease, hypertension, and cognitive function -- Cerebral microbleeds, small-vessel disease of the brain, hypertension, and cognition -- Imaging effects of hypertension on the brain: a focus on new imaging modalities and options -- The Joint Commission's initiatives to improve stroke care and what it means for acute stroke care and prevention.
  • This volume discusses the many ways to prevent, identify and control hypertension in African Americans, a common and potent risk factor for virtually all forms of cardiovascular-renal diseases. Comprehensive chapters address modifiable risk factors, such as lifestyle changes, especially sodium restriction, and appropriate combination pharmacotherapy. Emerging devices and evidence-based approaches that may also enhance effective blood pressure control and decrease the disparate cardiovascular disease risks, including MI, stroke, HF, and cardiorenal metabolic syndrome and diabetes are also discussed in detail. Written by a wide-range of experts in the field, Hypertension in High Risk African Americans: Current Concepts, Evidence-based Therapeutics and Future Considerations is a valuable resource for clinicians, researchers, health administrators and public health policy leaders to better understand the best practices and unique aspects of risk assessment and treatment of hypertension and co-morbid conditions in African Americans.
  • The importance of hypertension in the geriatric population / Ray W. Gifford and L. Michael Prisant -- Age-related changes in the cardiovascular system / R. Clinton Webb and Edward W. Inscho -- Aging, arterial stiffness, and systolic hypertension / Joseph L. Izzo -- Pharmacological and pharmacodynamic alterations in the elderly: application to cardiovascular therapies / Domenic A. Sica -- Epidemiology of hypertension in the older patient / William B. Kannel and Peter W. F. Wilson -- Nonpharmacological trials in the older patient / L. Michael Prisant and Dean U. Harrell -- Clinical trials of hypertension in older patient / L. Michael Prisant -- Blood pressure measurement in the older patients with hypertension / Jose Ramiro Arias-Vera and William B. White -- Clinical evaluation of the elderly hypertensive / L. Michael Prisant and Thomas W. Jackson -- Hypertension in the elderly: endocrine causes of secondary hypertension / Carlos M. Isales -- Diagnosis and management of hypertensive renal and renovascular disease in the elderly / Wanpen Vongpatanasin and Ronald G. Victor -- Heart failure in the older hypertensive patient / L. Michael Prisant ... [et al.] -- Management of ischemic heart disease in the older hypertensive patient: evaluation and management / Jan Laws Houghton -- Cerebrovascular disease in the elderly hypertensive / Fenwick T. Nichols, III -- Diuretics and beta-adrenergic blockers in the management of hypertension in the elderly / William C. Cushman -- Assessment of the role ace inhibitors in the elderly / Domenic A. Sica -- Use of angiotensin receptor blockers in the elderly / L. Michael Prisant -- Clinical trials with calcium antagonists in older patients with hypertension / William B. White and Sumeska Thavarajah -- Alpha-adrenoceptor blockers for management of hypertension in the elderly / James L. Pool -- Combination drug therapy in the elderly / L. Michael Prisant and Laura Lyngby Mulloy -- Attitudes regarding hypertension among older african-american adults / Wallace R. Johnson and Elijah Saunders -- Treatment of hypertension in the elderly diabetic patient / James R. Sowers and L. Michael Prisant -- Management of hypertension in older patients with arthritis / Sumeska Thavarajah and William B. White -- The clinician's role in improving therapeutic adherence and blood pressure control in older hypertensive patients / Brent M. Egan and Eni C. Okonofua.
  • Hypertension methods and protocols 2005
    Springer Protocols
  • Effectively manage the chronic problems of your hypertensive patients with the practical clinical tools inside Hypertension, 2nd Edition: A Companion to Braunwald's Heart Disease. This respected cardiology reference covers everything you need to know - from epidemiology and pathophysiology through diagnosis, risk stratification, treatment, outcome studies, concomitant diseases, special populations and special situations, and future treatments. Confidently meet the needs of special populations with chronic hypertensive disease, as well as hypertension and concomitant disease. Learn new methods of aggressive patient management and disease prevention to help ensure minimal risk of further cardiovascular problems. Benefit from the authors' Clinical Pearls to reduce complications of hypertension.
  • Brief history of image-guided therapy -- Noninvasive vascular diagnosis -- Invasive vascular diagnosis -- Diagnostic catheters and guidewires -- Balloon catheters -- Stents -- Thrombectomy devices -- Embolic protection devices -- Atherectomy devices -- Embolization agents -- Aortic stent-grafts -- Inferior vena cava filters -- Endovascular laser therapy -- Intellectual property management -- Clinical vascular examination -- Treatment of medical emergencies -- Radiation safety and protection in the interventional fluroscopy environment -- Management of risk factors for peripheral artery disease -- Principles of intraprocedural analgesics and sedatives -- Contrast agents -- Principles of thrombolytic agents -- Antiplatelet agents and anticoagulants -- Vasoactive agents -- Antibiotic prophylaxis in interventional radiology -- Angioplasty -- Restenosis -- Principles of arterial access -- Closure devices -- Principles of venous access -- Vascular anatomy of the upper extremity -- Anatomy of the lower limb -- Acute arterial occlusive disease of the upper extremity -- Acute lower extremity ischemia -- Chronic upper extremity ischemia and revascularization -- Aortoiliac revascularization -- Endovascular management of chronic femoropopliteal disease -- Infrapopliteal revascularization -- Subintimal angioplasty -- Management of extremity vascular trauma -- Management of postcatheterization pseudoaneurysms -- Endovascular treatment of peripheral aneurysms -- management of vascular artheritides -- Congential vascular anomalies: classification and terminology -- Management of low-flow vascular malformations -- Management of high-flow vascular anomalies -- Abdominal aorta and the inferior vena cava -- Aortic endografting -- Fenestrated stent-grafting of juxtarenalaortic aneurysms -- Management of thoracoabdominal aneurysms by branched endograft technology -- Endoleaks: classification, diagnosis, and treatment -- Endovascular treatment of dissection ot the aorta and its branches -- Alimentary tract vasculature -- Management of upper gastrointestinal hemorrhage -- Management of lower gastrointestinal bleeding -- Acute mesenteric ischemia -- Chronic mesenteric ischemia -- Renal vasculature -- Renovascular interventions -- Acute renal ischemia -- Renal artery embolization -- Management of renal angiomyolipoma -- Transvenous renal biopsy -- Transjugular liver biopsy -- Chemoembolization of hepatocellular carcinoma -- Radioembolization for hepatocellular carcinoma -- Embolotherapy for the management of liver malignancies other than hepatocellular carcinoma -- Radioembolization of liver metastases -- Bland embolization for hepatic malignancies -- Portal vein embolization -- Vascular intervention in the liver transplant patient -- Management of trauma to the liver and spleen -- Splenic embolization in nontraumatized patients -- Management of visceral aneurysms -- Intraarterial ports for chemotherapy -- Vascular anatomy of the pelvis -- Uterine fibroid embolization -- Peripartum hemorrhage -- Management of pelvic hemorrhage in trauma -- Management of male varicocele -- Management of female venous congestion syndrome.
  • This book presents a comprehensive overview of the major approaches to the imaging of the coronary arteries. These modalities, which include traditional angiography as well as intravascular and non-invasive imaging techniques, are used to diagnose and quantify the extent of obstructive disease due to atherosclerosis. Featuring contributions from leading authorities in the field, Imaging Coronary Atherosclerosis describes the visualization of coronary atherosclerosis through state-of the art techniques such as intravascular ultrasound, coronary near-infrared spectroscopy, computed tomography angiography, magnetic resonance imaging, and molecular imaging. This authoritative resource discusses how these modalities enhance the understanding of the disease process and the ways in which cardiologists can integrate them into clinical practice.
  • Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.
  • Ch. 1. Historical reflections on the inflammatory aspects of atherosclerosis -- Ch. 2. Morphology of atherosclerotic lesions -- Ch. 3. Clinical manifestations of atherosclerosis -- Ch. 4. Intra-aortic hematopoietic cells -- Ch. 5. The vascular-associated lymphoid tissue (VALT) -- Ch. 6. Vascular endothelial cells as immunological targets in atherosclerosis -- Ch. 7. The role of adhesion molecules and intimal dendritic cells in the initiation of atherosclerosis -- Ch. 8. Animal models of atherosclerosis -- Ch. 9. A Darwinian-evolutionary concept for atherogenesis: the role of immunity to HSP60 -- Ch. 10. Mediators of vascular inflammation -- Ch. 11. Pentraxins and atherosclerosis -- Ch. 12. Interleukin-33 and atherosclerosis -- Ch. 13. Proteomics of atherosclerosis -- Ch. 14. Adipokines, inflammation, and atherosclerosis -- Ch. 15. Natural antibodies and atherosclerosis -- Ch. 16. NK/NKT cells and atherosclerosis -- Ch. 17. Macrophages and atherosclerosis -- Ch. 18. Host pattern recognition receptors (toll-like receptors, RIG-I-Like receptors, NOD-like receptors) and atherosclerosis -- Ch. 19. Humoral antibodies -- Ch. 20. Adaptive T Cell immunity -- Ch. 21. Immunity to low-density lipoprotein -- Ch. 22. Extracellular matrix and smooth muscle cells -- Ch. 23. The role of infection in atherosclerosis and in plaque stability -- Ch. 24. Inflammatory biomarkers -- Ch. 25. Atherosclerosis in rheumatic diseases -- Ch. 26. Anti-inflammatory therapeutic approaches -- Ch. 27. Vaccination against atherosclerosis -- Ch. 28. Endocrinological aspects of atherosclerosis -- Ch. 29. Imaging of atherosclerosis -- Ch. 30. Future directions of atherosclerosis research and translation into clinical application -- Ch. 31. Controversies and open questions -- Index.
  • "This book provides practical hands-on advice on the use of alternative methods of hypertension treatment. It describes mechanisms of high blood pressure and hypertension, common causes of hypertension, and standard medications used to treat the disease and their side effects. The book details alternative methods of treating hypertension, emphasizing their mechanisms of action, similarities to standard medications, and practical implementation advice. Finally, it outlines guidelines for blood pressure goals, categorizes each treatment as medicine or alternative, and suggests ways of implementing an integrative approach to hypertension treatment"--Provided by publisher.
  • This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resource work for researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
  • This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations.
  • This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This third volume is focused on the most common cardiovascular events to provide an overview on pathogenesis and clinical aspects. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resourcefor researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
  • Internal carotid artery occlusion / O. Jansen -- Middle cerebral artery occlusion / C. Reidel -- Vertebrobasilar occlusion / D. Morhard and G. Schulte-Altedorneburg -- Dissections / T. Boeckh-Behrens -- Cerebral venous and sinus thrombosis / J. Linn -- Thrombolysis : intravenous thrombolysis / G. F. Hamann -- Intra-arterial thrombolysis / B. Eckert -- Mechanical recanalization materials : aspiration thrombectomy -- A. Kreusch and M. Knauth -- Temporary stenting in stroke patients / J. Klisch -- Retrievers and other thrombectomy systems / T. Struffert and A. Dörfler -- Treatment concepts and results : carotid-T occlusion / G. Fesl -- Occlusion of the middle cerebral artery / T. Liebig -- Basilar artery thrombosis / G. Schulte-Altedorneburg and H. Brückmann -- Cervical artery dissections / A. Rohr and H. Görike -- Treatment of acute cerebral venous occlusions / T. E. Mayer -- Equipment : stents, filters, and balloon systems / M. Holtmannspötter -- Extracranial carotid stenoses / M. Tietke and O. Jansen -- Intracranial stenoses / W. Kurre -- Subclavian steal syndrome / A. Berlis -- Proximal vertebral artery stenosis / N. Lummel and H. Brückmann -- Proximal stenosis of supra-aortic vessels / J. Berkefeld.
  • Introduction: What Is Translational Research -- Insights into heart development and regeneration -- Basis Of Cell Excitability And Cardiac Conduction System -- The Renin-Angiotensin-Aldosterone System In Cardiovascular Diseases -- Beta adrenergic receptors -- The hypothalamic-pituitary-adrenal axis in human health and disease -- Genetic Polymorphisms -- Genetic Polymorphisms and the Vascular Endothelium -- The role of microRNAs in Cardiovascular Disease -- Pathways To Myocardial Hypertrophy -- The multiple actions of the insulin-like growth factor-I signaling in the myocardium -- Calcium Cycling Circuits in Cardiac Physiology and Pathophysiology -- Inflammation and atherosclerosis -- Stress proteins and the Adaptive Response of the Heart -- The Mechanisms And Modalities Of Cell Death -- Repair of the infarcted myocardium -- Pathways to cardiac remodeling -- A Translational Approach to Probe the Arrhythmic Potential of the Heart: Therapeutic Considerations -- Animal Models Of Cardiovascular Disease -- Experimental in vitro assessment of cardiac function -- In vivo experimental assessment of cardiac function -- Non invasive imaging modalities for Cardiovascular Translational Research- Technical Considerations -- Cardiovascular Applications of Non-Invasive Imaging in Cardiovascular Diseases: from Bench to Bedside -- Molecular Imaging of Inflammation Using Echoardiography: Advances With the Use of Microbubbles -- Clinical Aspects And Genetics Of Cardiomyopathies -- Cardiorenal Syndrome: What Basic Research Can Contribute -- Clinical aspects of Cardiorenal Syndrome: consequences of therapy with the Renin-Angiotensin System Inhibitors -- Pre-, Peri-, and Post-Conditioning the ischemic myocardium: Challenges, Confounders and Expectations -- Gene Therapy for the Heart -- Cell therapy in cardiac diseases -- Moving Towards a Novel Paradigm in Drug Development for Worsening Heart Failure: The T1 Model (Mechanistic Translational Phase).
  • "Now in its 6th edition, Introduction to Vascular Ultrasonography, by Drs. John Pellerito and Joseph Polak, provides an easily accessible, concise overview of arterial and venous ultrasound. A new co-editor and new contributors have updated this classic with cutting-edge diagnostic procedures as well as new chapters on evaluating organ transplants, screening for vascular disease, correlative imaging, and more. High-quality images, videos, and online access make this an ideal introduction to this complex and rapidly evolving technique."--Publisher's website.
  • Angina -- Heart Failure -- Atrial Fibrillation -- Syncope and sudden death -- Systemic Hypertension -- Pulmonary Hypertension.
  • Part I. General thoracic surgery -- Part II. Adult Cardiac Sugery -- Part III. Congenital Cardiac Sugery.
  • "The 11th Edition of Kaplan's Clinical Hypertension continues to integrate the latest basic science findings and clinical trial data to provide current, practical, evidence-based recommendations for treatment and prevention of all forms of hypertension. As in previous editions, abundant algorithms and flow charts are included to aid clinicians in decision-making."--Provided by publisher.
  • Anatomy, dimensions, and terminology -- Hypothermia, circulatory arrest, and cardiopulmonary bypass -- Myocardial management during cardiac surgery with cardiopulmonary bypass -- Anesthesia for cardiovascular surgery -- Postoperative care -- Generating knowledge from information, data, and analyses -- Stenotic arteriosclerotic coronary artery disease -- Left ventricular aneurysm -- Postinfarction ventricular septal defect -- Mitral regurgitation from ischemic heart disease -- Mitral valve disease with or without tricuspid valve disease -- Aortic valve disease -- Combined aortic and mitral valve disease with or without tricuspid valve disease -- Tricuspid valve disease -- Infective endocarditis -- Cardiac rhythm disturbance -- Cardiac trauma -- Cardiac tumor -- Hypertrophic obstructive cardiomyopathy -- Cardiomyopathy -- Cardiac transplantation -- Mechanical circulatory support -- Pericardial disease -- Acute traumatic aortic disruption -- Acute aortic dissection -- Chronic thoracic and thoracoabdominal aortic disease -- Diseases of the pulmonary arteries -- Acquired diseases of the systemic veins -- Congenital heart disease in the adult, Atrial septal defect and partial anomalous pulmonary venous connection -- Total anomalous pulmonary venous connection -- Cor triatriatum -- Unroofed coronary sinus syndrome -- Atrioventricular septal defect -- Ventricular septal defect -- Congenital sinus of valsalva aneurysms and aortico-left ventricular tunnel -- Patient ductus arteriosus -- Ventricular septal defect with pulmonary stenosis or atresia -- Pulmonary stenosis and intact ventricular septum -- Pulmonary atresia and intact ventricular septum -- Tricuspid atresia and single-ventricle physiology -- Ebstein anomaly -- Truncus arteriosus -- Aortopulmonary window -- Origin of the right or left pulmonary artery from the ascending aorta -- Congenital anomalies of the coronary arteries -- Congenital aortic stenosis -- Coarctation of the aorta and interrupted aortic arch -- Aortic atresia and other forms of hypoplastic left heart physiology -- Congenital mitral valve disease -- Vascular ring and sling -- Complete transposition of the great arteries -- Double outlet right ventricle -- Double outlet left ventricle -- Congenitally corrected transposition of the great arteries and other forms of atrioventricular discordant connection -- Double inlet ventricle and atretic atrioventricular valve -- Anatomically corrected malposition of the great arteries -- Atrial isomerism.
  • This book is an introduction to interventional radiology. Written in a case-based format, the book is subdivided into ten chapters made up of ten vascular and non-vascular interventional radiology cases. Each case contains illustrations and legends describing the imaging findings and technical details of each intervention, comments from anatomical, physiopathological and radiological standpoints, as well as a description of the interventional procedure and the required interventional devices. The book is aimed at vascular and non-vascular interventional radiologists, vascular surgeons, radiology.
  • The lipid-rich and otherwise challenging nature of many key tissues complicates many aspects of current research, and applications of the unique nature of lipoproteins and their biological effects has engendered unique and vital methodologies. In Lipoproteins and Cardiovascular Disease: Methods and Protocols, experts in the field present a compendium of advanced and classical molecular biology methods targeted towards lipoprotein, atherosclerosis, and vascular biology research, bringing together in a single volume an updated set of protocols and strategies for methods now driving the most recent advances, along with classical methods that are still widely used. Among the many topics covered in this cutting-edge work, the book delves into crucial techniques such as quantitative real-time PCR, microarrays, RT-PCR laser capture microdissection, and tissue-specific gene overexpression, knockout, and knockdown methodologies, including AAV as a liver-directed gene delivery vehicle. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and valuable notes which highlight tips on troubleshooting and avoiding known pitfalls. Comprehensive and easy to use, Lipoproteins and Cardiovascular Disease: Methods and Protocols serves both novices and experts alike as a complete guide for any researcher with an interest in lipoproteins and their significant biological effects.
  • Claudication : clinical diagnosis and differential diagnosis / Dennis G. Caralis -- Noninvasive diagnostic evaluation of peripheral arterial disease / Nicholas Labropoulos and Apostolos K. Tassiopoulos -- Smoking and smoking cessation / Albert Bellg and Aristides N. Mavridis -- Peripheral arterial disease and diabetes / George L. Bakris -- Hyperlipidemia in peripheral arterial disease / Ambika Babu, C.R. Kannan, and Theodore Mazzone -- Hypertension and peripheral vascular disease / Anjula Gandhi, Jay Garg, and George L. Bakris -- Physical inactivity is a risk factor for lower extremity arterial disease and coronary heart disease / Dennis G. Caralis and Stamatis Dimitropoulos -- Pathogenesis of atheroslerotic vascular disease / Bassem Jamil Basha, George L. Bakris, and James R. Sowers -- Lower extremity arterial disease coexisting with coronary artery disease : management and prognosis / Dennis G. Caralis -- Medical therapy of claudication and lower extremity arterial disease / Dennis G. Caralis -- Exercise therapy for low extremity arterial disease / Peter F. Kokkinos -- Endovascular strategies for management of claudication and lower extremity arterial disease / Michael C. Brunner and Dennis G. Caralis -- Severe lower extremity arterial disease : limb salvage and revascularization failure / Chad E. Jacobs and Walter J. McCarthy.
  • "This book summarizes the great progress in the treatment of cardiovascular disease (CVD). Due to improved therapies, preventive strategies and increased public awareness, CVD mortality has been on the decline for both genders. Unfortunately, the decline has been less prominent for women, and CVD remains the leading cause of mortality for women in the United States and is responsible for a third of all deaths of women worldwide. Management of Cardiovascular Disease in Women provides a comprehensive overview of differences in cardiac problems in women including the challenges and limitations of the available literature. Unique aspects to women's heart health such as pregnancy, the impact of emotional stress and other psychosocial issues are discussed by leading experts in the field. They therefore provide important insight to cardiovascular care in women, making this book an essential resource for a wide range of practitioners including cardiologists, primary care providers, internists, and reproductive healthcare professionals."--Publisher's website.
  • This book explores the challenges of treating foot complications associated with diabetes,℗ℓ a major challenge for societies the world over. Authors include experienced podiatrists, nurses and doctors,℗ℓ all of whom℗ℓ work in the field of diabetes foot care. The book is divided into prevention and early management, management of major complications, prevention of recurrence and how to structure a team.℗ℓ In each area, the authors describe their practical experiences and discuss how they have addressed clinical challenges. Management of Diabetic Foot Complications provides useful information for anyone responsible for the care of people with diabetes who may be at risk of developing foot complications.
  • Management of hypertension in diabetes / Samy I. McFarlane -- Hypertension in diabetes : prevalence, risks and treatment targets / Antonio Coca & Miguel Camafort -- Nonpharmacological management of hypertension in diabetes / Marie-Ève Leblanc, Caroline Rhéaume, Lyne Cloutier, Jean Lefebvre & Paul Poirier -- Pharmacological management of hypertension in diabetes / Tonje A. Aksnes, Sigrid N. Skårn & Sverre E. Kjeldsen -- Role of angiotensin receptor blockers in diabetes / Philippe Akhrass, John N. Makaryus, Amgad N. Makaryus, Arathy Vamadevan & Samy I. McFarlane -- Treatment recommendations and consensus guidelines / Vivencio Barrios Alonso & Carlos Escobar Cervantes.
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  • An ever growing population of patients are affected by cardiac disease. Most of these diseases are chronic in nature and require long term outpatient follow up. Subsequently, outpatient providers are finding themselves responsible for an increasing number of patients with cardiovascular issues. Appropriate diagnosis and management of cardiac disease is essential to providing high quality care in an efficient manner. There is a wide spectrum of providers involved in the care of these patients, many of which are not cardiologists. The Manual of Outpatient Cardiology is written in a practical, didactic format designed to deliver point-of-care information to practitioners of cardiology and assist non-cardiologists with the efficient management of cardiac disease. Highly illustrated with schematics and useful clinical figures, this book is an essential reference to all outpatient cardiology procedures.
  • Key issues of vascular pathoanatomy / Frank Kolodgie ... [et al.] -- Key issues of vascular pathophysiology / Axel R. Pries, Ivo Buschmann, Helmut Habazettl -- Magnetic resonance imaging / Dietrich Baumgart, Thomas Egelhof -- X-ray coronary angiography / Peter Lanzer -- Intracoronary ultrasound / Anuja Nair ... [et al.] -- Pressure wire / Wilbert Aarnoudse, Cees-joost Botman, Nico H.J. Pijls -- The decision-making process in percutaneous coronary interventions / Lutz Prechelt, Peter Lanzer -- Devices / Wolfram Schmidt, Klaus-Peter Schmitz -- Intracranial vessels / Hans Henkes ... [et al.] -- Internal carotid artery / Peter Lanzer, Ralf Weser -- Coronary arteries / Peter Lanzer, L.D. Timmie Topoleski -- Thoracic aorta / Tim C. Rehders ... [et al.] -- Abdominal aortic aneurysm / Martin Köcher, Petr Utíkal -- Renal arteries / Peter Lanzer, Ralf Weser -- Abdominal aorta, iliac, and lower extremity arteries / Peter Lanzer, Ralf Weser -- Haemodialysis shunts / Dierk Vorwerk -- Venous diseases / Zubin Irani, John A. Kaufman -- Foreign bodies / Haresh G. Mehta, Stephan Windecker, Bernhard Meier.
  • This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided by experts in the field, with illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Diagnostic approaches including imaging and novel physiologic tests, including gastric tonometry and oxygen light spectroscopy are also covered. Mesenteric Vascular Disease: Current Therapy will serve as a very useful resource for clinicians, surgeons, interventionalists, gastroenterologists and researchers dealing with and interested in mesenteric vascular diseases.
  • Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. Each year, heart disease kills more people than cancer. Patients are treated by a variety of specialists and primary care practitioners, depending on the organ system involved. This volume enables practitioners to assess the adverse effects of the complete range of drugs used in cardiovascular medicine, including antihypertensive drugs, and drugs used in the treatment.
  • This book presents a new method for analyzing the structure and function of the biological branching systems of fractal trees, with a focus on microcirculation. Branching systems in humans (vascular and bronchial trees) and those in the natural world (plants, trees, and rivers) are characterized by a fractal nature. To date, fractal studies have tended to concentrate on fractal dimensions, which quantify the complexity of objects, but the applications for practical use have remained largely unexplored. This book breaks new ground with topics that include the human retinal microcirculatory network, oxygen consumption by vascular walls, the Fh raeus-Lindqvist effect, the bifurcation exponent, and the asymmetrical microvascular network. Readers are provided with simple formulas to express functions and a simulation graph with in vivo data. The book also discusses the mechanisms regulating blood flow and pressure and how they are related to pathological changes in the human body. Researchers and clinicians alike will find valuable new insights in these pioneering studies.
  • Part 1. General principles of mitochondria and the heart -- Introduction to Mitochondria in the Heart -- Methods to Study Mitochondrial Structure and Function -- Mitochondrial Structure, Composition, and Dynamics -- Mitochondrial Biogenesis -- Mechanisms of Bioenergy Production in Mitochondria -- Bioenergetics Interplay Between Cardiac Mitochondria and Other Subcellular Compartments -- Part 2. Heart mitochondria signal transduction. Stem cells -- Endothelial Mitochondria: Contribution to Cardiovascular Function and Disease -- Heart Mitochondria: Receivers and Transmitters of Signals -- Stem Cells and Mitochondria -- Part 3. Stress and cell death -- Heart Mitochondrial ROS and Oxidative Stress -- Cell-Death Pathways and Mitochondria -- Part 4. Mitochondria in Pediatric Cardiology -- Mitochondria in Pediatric Cardiovascular Diseases -- Part 5. The aging heart and mitochondria -- Mitochondria in the Aging Heart -- Part 6. Mitochondria in Atherosclerosis, hypertension and ischemia -- The Role of Mitochondria in Atherosclerosis -- The Role of Mitochondria in Hypertension -- Role of Mitochondria in Ischemia and Cardioprotection -- Part 7. Mitochondria in Heart Failure and Dysrhythmias -- Mitochondrial Dynamics in Health and Disease -- Mitochondria Play an Essential Role in Heart Failure -- Mitochondria and Cardiac Dysrhythmias -- Part 8. Mitochondria in heart metabolism -- Diabetes and Cardiac Mitochondria -- The Role of Mitochondria in the Metabolic Syndrome and Insulin Resistance -- Thyroid Hormone and Myocardial Mitochondria -- Part 9. Mitochondrial Therapy -- Targeting the Mitochondria in Cardiovascular Diseases -- Part 10. Looking to the future of mitochondria and the heart -- Current Progress and Future Perspectives: Toward Mitochondrial Medicine.
  • This book provides the most up-to-date coverage of the combined use of imaging modalities in order to acquire important functional and morphological information on cardiovascular disease and enhance disease detection. The recent developments in PET/MRI, cardiac CT, PET/CT, and SPECT/CT and their impact on clinical practice are explained, and special attention is also devoted to imaging parameters and protocols for use in practice and research. The utility of multimodality imaging techniques for diagnosis and evaluation is discussed in the context of various clinical scenarios, including ischemic cardiomyopathy, myocarditis, myocardial fibrosis, cardiac sarcoidosis, and atherosclerotic plaque disease. Written by renowned researchers and clinicians, the book is an ideal concise reference on today's most advanced imaging techniques. It will appeal to all clinicians, trainees, and technicians who are involved in the diagnosis and risk assessment of cardiovascular disease.
  • Calcium Overloading-Induced Oxidative Stress-Mediated Cellular and Subcellular Remodeling -- Intracellular MMP-2: Role in Normal and Diseased Hearts -- Control of the Mesenchymal-Derived Cell Phenotype by Ski and Meox2: A Putative Mechanism for Postdevelopmental Phenoconversion -- Elevated Na+-H+ Exchanger Expression and Its Role in Myocardial Dise -- Impact of Perinatal Chronic Hypoxia on Cardiac Tolerance to Acute Ischemia -- Stem Cell, MicroRNA and Redox Cycling -- Cardiac Cell Therapy: Present and Future -- Macroscopic and Microscopic Aspects of Cardiac Dysfunction in Congestive Heart Failure -- Cardiac Dysfunction and Metabolism: Unravelling the Molecular Cross-Talk -- Metabolic Remodelling of the Hypertrophied Heart -- Mechanisms for the Regulation of Phospholipase C Gene Expression in Cardiac Hypertrophy -- Molecular Changes in Fatty Acid Oxidation in the Failing Heart -- Cardiolipin Metabolism in Experimental and Human Heart Failure -- Mechanisms Underlying Development of Cardiomyocyte Hypertrophy via Na-H Exchange Stimulation -- The Structural Basis of Cardiac Dysfunction in Human Heart Failure -- Hormonal Mechanisms of Cardiac Remodeling in Heart Failure -- Modulators of Remodeling After Myocardial Infarction -- Phosphodiesterase-5 Inhibitors in Protection Against Doxorubicin-Induced Cardiomyopathy -- Molecular Basis of Pulmonary Hypertension in Left Heart Failure -- Modulation of Gi Protein Expression in Hypertension: Molecular Mechanisms -- Vascular Dysfunction in Heart Disease -- Cellular and Molecular Mechanisms Associated with Salicylate Inhibition of Intimal Hyperplasia Following Balloon Catheter-Induced Vascular Injury -- Involvement of Growth Factor Receptor and Nonreceptor Protein Tyrosine Kinases in Endothelin-1 and Angiotensin II-Induced Signaling Pathways in the Cardiovascular System -- Sarco/Endoplasmic Reticulum Ca2+ Pump Damage by Oxidative Stress: Implications for Ca2+ Entry -- Obesity-Hypertension: Leptin as the Common Link to Cardiovascular and Renal Dysregulation -- Cardiorenal Protection in Diabetes Mellitus -- Molecular Mechanisms in the Pathogenesis of Diabetic Cardiomyopathy.

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