Books by Subject
Tropical Medicine and Parasitology
- antimicrobe.org DatabaseIncludes information on antimicrobial therapy and alternative therapy when the drug of choice cannot be given. The resource delivers information via review articles, capsule summaries, mini-reviews, and a guided PubMed search to pick up post-publication research.
- Appraisal of the status of Chagas disease in the United States. 1st ed. 2012, ScienceDirectDuring the first half of the 20th century, Chagas disease was assumed to be absent from the U.S. and considered an exotic disease, until the first two indigenous cases were discovered, almost simultaneously, in Texas, 1955. Since that time four indigenous cases have been documented in several places in the country. Although the disease is still considered uncommon in the US, this disease is not longer an exclusive Latin American illness. Physicians in the US are often unaware of the characteristics of the diseases, and are likely overlooking locally acquired cases. The influx of an estimated 300,000 Latin American immigrants with the Chagas parasite means that there is an urgent need for physicians and public health officials to become aware. This title critically reviews old and new literature, help to create greater awareness of the disease in the US and helps in the evaluation of certain epidemiological and public health issues. Helps to create greater awareness of Chagas disease in the USA Helps to evaluate epidemiological and public health issues Facilitates accurate and necessary future public health interventions.
- Ascaris the neglected parasite 2013, ScienceDirectThis book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines. Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans, as disability adjusted life years approximating 10.5 million. Ascaris larvae develop in host parenteral tissues, and the resultant pathology has been condemnation. Ascariasis, despite its staggering global prevalence and the sheer numbers of people it infects, remains a classic neglected disease. However, renewed interest in the consequences of early infection with worms from the perspective of immune modulation, co-infections and the development of allergy further enhances the relevance of these parasites. Brings together a wide range of topics and approaches and recent, comprehensive and progressive research concerning the neglected parasite Ascaris Provides a blueprint of how a single parasite entity can stimulate interest in basic biology, clinical science, veterinary science, public health and epidemiology Presents a wealth of new insights given that a book on this parasite has not been published for over 20 years 16 chapters from a range of top authors from around the world.
- This book gathers contributions by 16 international authors on the phenomenon bats, shedding some light on their morphology, the feeding behaviors (insects, fruits, blood) of different groups, their potential and confirmed transmissions of agents of diseases, their endo- and ectoparasites, as well as countless myths surrounding their lifestyle (e.g. vampirism, chupacabras, batman etc.). Bats have been known in different cultures for several thousand centuries, however their nocturnal activities have made them mysterious and led to many legends and myths, while proven facts remained scarce. Even today, our knowledge of bats remains limited compared to other groups in the animal kingdom. Also, their famous ability to avoid collisions with obstacles during their nightly flights with the help of a sophisticated and unique system using ultrasound waves (which are transmitted and received) is as poorly studied as birds finding their way from continent to continent. In recent times, where globalization transports millions of people and goods from one end of the earth to the other, there are increased risks posed by agents of diseases, as a result of which bats have received increasing attention as potential vectors. These suppositions are based on their proven transmission of viruses such as rabies.
- Bioinformatics in tropical disease research a practical and case-study approach 2008, NCBI Bookshelf"This book is intended to serve both as a textbook for short bioinformatics courses and as a base for a self-teaching endeavor. "--Introduction.
- The stages of blastocystis have been known for 101 years. However, many facts are still disputed, e.g. even the question whether it is a true pathogen or a commensal present in sometimes life-threatening diarrheas.The present book evaluates in chapters contributed by renowned researchers the latest findings on: landmarks in the discovery of blastocystis; epidemiology, transmission and zoonotic potential; morphology of human and animal blastocystis isolates; clinical aspects of blastocystis infections; behavioral decision analysis: what makes us sick?; blastocystis-host interactions; molecular approaches on the systematical position; genetic polymorphism; blastocystis from a statistical point of view; diarrheas due to different agents of disease; zoonotic diseases in comparison. As such, this book provides a broad range of information for people working in this field, for physicians and veterinarians who are confronted with clinical cases, teachers, students and technical staff members in the fields of microbiology, parasitology and diagnostic methods -- P.  of cover.
- Challenges in infectious diseases 2013, Springer"This new volume ... aims to address demands and challenges that various infections present to the world at large ('global challenges'), such as the HIV pandemic, continuous threat of spreading common multiresistant pathogenic bacteria, multidrug and extensive drug-resistant tuberculosis, and the influence we can expect on these epidemics with global climate change and international urbanization ... Chapters on these various topics authored by world-renowned experts on these areas provide state-of-the-art reviews on epidemiology, biology, clinical aspects, prevention, current approaches to control, and prevention such as new vaccines, and reassessment of past and present methods are discussed"--Preface.
- Clinical cases in tropical medicine 2015, ClinicalKeyTest your knowledge in tropical medicine with Clinical Cases in Tropical Medicine! Boasting an easily accessible, highly templated format and full-color photographs throughout, this medical reference book is designed to help anyone in the field better identify the tropical diseases they'll encounter. As a companion product to Manson's Tropical Diseases, Clinical Cases in Tropical Medicine offers over 75 cases covering today's most prevalent diseases. It's an ideal study tool for infectious diseases fellows, doctors preparing for exams, primary care doctors with patients returning from abroad, and global health nurses and practitioners alike. Stay at the forefront of tropical medicine with in-depth coverage of the latest research, including tropical neurology and AIDS- and HIV-associated diseases and treatments.Study as efficiently as possible with help from a Q&A format and succinct summary boxes.Expand your knowledge concerning rare and neglected tropical diseases, as well as how diagnosis and treatment takes place in resource-poor settings.Gain a complete understanding of tropical diseases with this companion product to Manson's Tropical Diseases, 23rd edition. A reading list at the end of each case will directly refer to a corresponding chapter in Manson's, further expediting study.
- Corynebacterium diphtheriae and related toxigenic species genomics, pathogenicity and applications 2014, SpringerCorynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects.
- Cryptosporidium parasite and disease 2014, SpringerThis new volume on Cryptosporidium and Cryptosporidiosis discusses all relevant aspects of the biology, molecular biology, host-parasite interaction, epidemiology as well as diagnosis and treatment of these widespread parasites. It represents a useful guide for physicians, microbiologists, veterinarians and water professionals seeking advanced knowledge and guidance about these important parasitic pathogens. A section on practical lab procedures discusses step-by-step guidelines for sample preparation and lab procedures. The new book may further serve as a reference work for graduate students in medical and veterinary microbiology.
- Cysticercosis of the human nervous system 2014, SpringerNeurocysticercosis (neural infection by larvae of Taenia solium) occurs when humans become intermediate hosts of the tapeworm Taenia solium after ingesting its eggs, usually directly from a Taenia carrier. Nowadays, the disease is the most common helminthic infection of the nervous system in humans, and a major cause of acquired epilepsy. It has long been endemic in developing countries of Latin America, sub-Saharan Africa, the Indian subcontinent, and Southeast Asia. Recently, however, mass migration from endemic to non-endemic areas and growth in overseas travel have resulted in an increase in the prevalence of cysticercosis in countries where it was formerly considered exotic. The introduction of modern neuroimaging and serologic techniques has improved the diagnosis of neurocysticercosis, and the development of potent cysticidal drugs has changed the prognosis of most affected patients. Nevertheless, much remains to be learned about this parasitic disease. This book provides a comprehensive and up-to-date review of the various aspects of cysticercosis of the nervous system that will be of interest to all who are involved in the care of patients with the disease. Epidemiology, neuropathology, immunopathogenesis, clinical manifestations, diagnosis, and management are all thoroughly discussed based on current evidence and practice.
- Defending life--the nature of host-parasite relations 2007, Springer
- Dictionary of parasitology 2005, CRCnetBASE
- Digenetic trematodes 2014, SpringerPart 1. General aspects of trematodes. Form and function in the Digenea / Robert C. Peoples and Bernard Fried -- The systemics of the Trematoda / Aneta Kostadinova and Ana Pérez-del-Olmo -- part 2. Trematodes of interest in human health. Schistosomiasis / Fred A. Lewis and Matthew S. Tucker -- Fascioliasis / Santiago Mas-Coma, M. Adela Valerno and M. Dolores Bargues -- Paragonimiasis / David Blair -- Liver flukes: Clonorchis and Opisthorchis / Weerachai Saijuntha, Paiboon Sithithaworn, Nadda Kaitsopit, Ross H. Andrews, and Trevor N. Petney -- Intestinal trematode infections / Rafael Toledo, Carla Muñoz-Antoli, and J. Guillermo Esteban -- Epidemiology of trematode infections / Jong-Yil Chai -- Diagnosis of human trematode infections / J. Guillermo Esteban, Carla Muñoz-Antoli, Rafael Toledo, and Lawrence R. Ash -- part 3. Trematodes of interest in veterinary and wildlife disease. Schistosomatoidea and Diplostomoidea / Petr Horák, Libuš Kolá̌řová, and Libor Mikeš -- Amphistomes / Veena Tandon, Bishnupada Roy, Jollin Andrea Shylla -- Dicrocoeliidae family: major species causing veterinary diseases / M. Yolanda Manga-González and M. Carmen Ferreras -- Selected wildlife trematodiasis / Jane E. Huffman -- Index.
- Drug resistance in leishmania parasites consequences, molecular mechanisms and possible treatments 2013, Springer
- Ecology, epidemiology, and evolution of parasitism in Daphnia 2005, NCBI Bookshelf
- Encyclopedia of parasitology. 3rd ed. 2008, Springerv. 1. A-M -- v. 2. N-Z.
- Epidemiological and molecular aspects on cholera 2011, SpringerAsiatic cholera: mole hills and mountains -- Endemic and epidemic cholera in Africa -- Phenotypic and molecular characteristics of epidemic and non-epidemic vibrio cholerae strains isolated in Russia and certain countries of Commonwealth of Independent States (CIS) -- The re-emergence of cholera in the Americas -- The evolution of vibrio cholerae as a pathogen -- Molecular epidemiology of toxigenic vibrio cholerae -- Diversity and genetic basis of polysaccharide biosynthesis in vibrio cholerae -- Significance of the SXT/R391 family of integrating conjugative elements in vibrio cholerae -- Small molecule signaling systems in vibrio cholerae -- Vibrio cholerae flagellar synthesis and virulence -- Filamentous phages of vibrio cholerae O1 and O139 -- Pathogenic potential of non-O1, non-O139 vibrio cholerae -- Proteases produced by vibrio cholerae and other pathogenic vibrios: pathogenic roles and expression -- Toxins of vibrio cholerae and their role in inflammation, pathogenesis, and immunomodulation -- Vibrio cholerae hemolysin: an enigmatic pore-forming toxin -- Integrin-mediated antimicrobial resistance in vibrio cholerae -- Aquatic realm and cholera -- Management of cholera.
- Food-borne parasitic zoonoses fish and plant-borne parasites 2007, Springer
- Foodborne parasites 2006, Springer
- Forgotten people, forgotten diseases the neglected tropical diseases and their impact on global health and development. 2nd ed. 2013, ebraryProvides an overview of the neglected tropical diseases (NTDs) and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development.
- Giardia-- a model organism 2011, Springer1. Taxonomy of Giardia species -- 2. Epidemiology of giardiasis in humans -- 3. Waterborne and environmentally-borne giardiasis -- 4. Giardia in pets and farm animals, and their zoonotic potential -- 5. Genomics of Giardia -- 6. The glycoproteins of Giardia -- 7. Mass spectrometric analysis of phospholipids and fatty acids in Giardia lamblia -- 8. Giardia metabolism -- 9. The ultrastructure of Giardia during growth and differentiation -- 10. Cell cycle regulation and cell division of Giardia -- 11. The Giardia mitosomes -- 12. Signaling pathways in Giardia lamblia -- 13. Transcription and recombination of Giardia -- 14. Intracellular protein trafficking -- 15. Post-transcriptional gene silencing and translation in Giardia -- 16. Antigenic variation of Giardia -- 17. Interaction of Giardia with host cells -- 18. Primary microtubule structures in Giardia -- 19. Pathophysiological processes and clinical manifestations of Giardiasis -- 20. Immunology of giardiasis -- 21. Vaccination against Giardia -- 22. Diagnosis of human giardasis -- 23. Methods for Giardia culture, cryopreservation, encystation, and excystation in vitro -- 24. Synchronization of Giardia -- 25. Methods for Giardia transfection and gene expression -- 26. Biological resource centers for Giardia research.
- Introduction -- Clinical disease and epidemiology -- Objectives of treatment -- Resistance to antimalarial medicines -- Antimalarial treatment policy -- Diagnosis of malaria -- Treatment of uncomplicated P. falciparum malaria -- Treatment of severe falciparum malaria -- Treatment of malaria caused by P. vivax, P. ovale or P. malariae -- Mixed malaria infections -- Complex emergencies and epidemics -- Case management in the context of malaria elimination -- Mass drug administration.
- Health research in developing countries a collaboration between Burkina Faso and Germany 2005, Springer
- Heat shock proteins of malaria 2014, SpringerThe Importance of Molecular Chaperones in Survival and Pathogenesis of the Malaria Parasite Plasmodium falciparum / Jude Przyborski -- General Structural and Functional Features of Molecular Chaperones / Adrienne L. Edkins and Aileen Boshoff -- The Role of Hsp70s in the Development and Pathogenicity of Plasmodium Species / Addmore Shonhai -- Role of the Hsp40 Family of Proteins in the Survival and Pathogenesis of the Malaria Parasite / Eva-Rachele Pesce, Alexander G. Maier and Gregory L. Blatch -- Role of Hsp90 in Plasmodium falciparum Malaria / Dea Shahinas and Dylan R. Pillai -- The Role of Parasite Heat Shock Proteins in Protein Trafficking and Host Cell Remodeling / Paul R. Gilson, Sarah C. Charnaud and Brendan S. Crabb -- Role of Heat Shock Proteins in Immune Modulation in Malaria / Evelyn Böttger and Gabriele Multhoff -- Establishment of Plasmodium falciparum Extracellular Compartments in its Host Erythrocyte / Alassane Mbengue, Laurence Berry and Catherine Braun-Breton -- Chaperones and Proteases of Plasmodium falciparum / Kaiyin Liu and Walid A. Houry -- Heat Shock Proteins as Targets for Novel Anti-Malarial Drugs / Manish Grover, Shweta Chaubey and Utpal Tatu -- Heat Shock Proteins of Malaria: What Do We Not Know, and What Should the Future Focus Be? / Addmore Shonhai and Gregory L. Blatch.
- Helminth control in school-age children a guide for managers of control programmes.. 2nd ed. 2011, WHO
- How helminths alter immunity to infection 2014, Springer"Helminth infections are common, cause considerable pathology, and alter a host's immune profile. This can have important consequences not only on the host's ability to control a helminth infection, but also on their ability to control unrelated infections. In endemic areas, understanding how helminth infection influences the outcome of common infectious diseases and changes the efficacy of childhood vaccination programs is an important public health question. This book reviews how host immunity to helminths alters our ability to respond to the major pathogens that exist in helminth endemic regions. Current understanding of how helminths alter important but relatively neglected contributors to the host's anti-helminth immune responses are addressed, namely host antibody responses and how maternal infection may alter a child's immune development. These are discussed in relation to the control of helminth infection and unrelated infections. Also covered are how helminth infections alter the host's ability to control TB, HIV and malarial infections along with neglected bacterial infections, such as cholera, and how endemic helminth infections are likely to alter our ability to respond to life-saving vaccination strategies"--Publisher's description.
- Hunter's Tropical m edicine and emerging infectious disease. 9th ed. 2012, ClinicalKeypt. 1. Clinical practice in the tropics -- pt. 2. Viral diseases -- pt. 3. Bacterial infections -- pt. 4. The mycoses -- pt. 5. Protozoal infections -- pt. 6. Helminthic infections -- pt. 7. Poisonous and toxic plants and animals -- pt. 8. Nutritional problems and deficiency diseases -- pt. 9. Vector transmission of diseases and zoonoses -- pt. 10. The sick returning traveler -- pt. 11. Laboratory diagnosis of parasitic diseases -- pt. 12. Drugs used in tropical medicine.
- Imaging of parasitic diseases 2007, Springer
- Immunology and immunopathogenesis of malaria 2005, SpringerThe dissection of CD8 T cells during liver-stage infection / U. Krzych and R.J. Schwenk -- Early interactions between blood-stage Plasmodium parasites and the immune system / B.C. Urban, R. Ing, and M.M. Stevenson -- Longevity of the immune response and memory to blood-stage malaria infection / A.H. Achtman ... [et al.] -- Experimental models of cerebral malaria / C. Engwerda ... [et al.] -- Glycosylphosphatidylinositols in malaria pathogenesis and immunity : potential for therapeutic inhibition and vaccination / C.S. Boutlis ... [et al.] -- The immunology and pathogenesis of malaria during pregnancy / J.G. Beeson and P.E. Duffy.
- "THE INFECTIOUS DISEASES OF HAITI is one in a series of GIDEON e-books which summarize the status of individual infectious diseases, in every country of the world. Data are based on the GIDEON database (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing search of the medical literature. Chapters are arranged alphabetically, by disease name. Each section is divided into four sections: 1. Descriptive epidemiology; 2. Summary of clinical features; 3. Status of the disease in Haiti ; 4. References. The initial items in the first section, Descriptive epidemiology, are defined as follows: Agent: Classification (e.g., virus, parasite) and taxonomic designation; Reservoir: Any animal, arthropod, plant, soil or substance in which an infectious agent normally lives and multiplies, on which it depends primarily for survival, and where it reproduces itself in such a manner that it can be transmitted to a susceptible host; Vector: An arthropod or other living carrier which transports an infectious agent from an infected organism or reservoir to a susceptible individual or immediate surroundings; Vehicle: The mode of transmission for an infectious agent. This generally implies a passive and inanimate (i.e., non-vector) mode. There are 347 generic infectious diseases in the world today. 198 of these are endemic, or potentially endemic, to Haiti. A number of other diseases are not relevant to Haiti and have not been included in this book. In addition to endemic diseases, we have included all published data regarding imported diseases and infection among expatriates from this country. The availability and quality of literature regarding specific infectious diseases varies from country to country. As such, you may find that many of the sections in this book are limited to a general discussion of the disease itself - with no data regarding the country under review. Since this book focuses on Geographic Medicine, it does not include detailed information on diagnostic testing, pathogenesis, therapy or molecular biology. Many of the diseases are generic. For example, such designations as Pneumonia bacterial and Urinary tract infection include a number of individual diseases. These appear under the subheading, Synonyms, listed under each disease. The entire book will be updated on a regular basis.
- Intolerable burden of malaria. II what's new, what's needed 2004, NCBI Bookshelf
- Kala azar in South Asia current status and challenges ahead 2011, Springerpt. 1. Introduction to Kala-Azar -- pt. 2. Therapeutic strategy to deal with emergence of drug resistance -- pt. 3. Diagnostic strategy enhancing Kala-Azar elimination program -- pt. 4. PKDL and its implications in eliminating Kala-azar -- pt. 5. New challenges confronting Kala azar elimination programme and their possible solutions.
- Leishmania and leishmaniasis 2013, SpringerLeishmania-related illnesses remain among the world s deadliest neglected tropical diseases, affecting approximately 12 million people in 88 countries. The mortality rate is substantial, contributing to nearly two million disability-adjusted life years. As more is understood about this parasite and its effects, work toward prevention, control, and treatment continues apace. Leishmania and Leishmaniasis will address the parasite and its attendant disease, which manifests in three syndromes: Visceral (VL), Cutaneous (CL) and Mucocutaneous Leishmaniasis (ML). The morphology and life cycles of the various species will be among the topics addressed in Part One. Part Two will focus on immunology, including host-immune response to Leishmania infection, cross-immunity between the different species and adoptive transfer of immunity. Parts Three and Four will address how Leishmania invade and survive, the clinical features of the disease, and its diagnosis. Drugs, vaccines and treatment will be thoroughly explored, including experimental models of therapeutics. Leishmania and Leishmaniasis will provide a thorough examination of a parasite, the illnesses it causes and the misery it continues to visit upon large segments of the population.
- Malaria immunology. 2nd ed. / 2002, Kargerpt. 1. Malaria parasites and disease -- Structure and life cycle / H. Fujioka -- Malaria parasites and the Anopheles mosquito /G. Dimopoulos -- Malaria: pathogenicity and disease / M. English -- pt. 2. Malaria antigens -- Sporozoite antigens: biology and immunology of the circumsporozoite protein and thrombospondin-related anonymous protein / P. Sinnis -- Immune responses to liver-stage parasites: implications for vaccine development / M.R. Hollingdale -- Merozoite antigens involved in invasion / K. Berzins -- Asexual blood stages of malaria antigens: cytoadherence / D.I. Baruch -- Rosetting and autoagglutination in Plasmodium falciparum / V. Fernandez -- Sexual and sporogonic stage antigens / R.W. Sauerwein -- pt. 3. Malaria infection: immunity and regulation -- Mouse models of blood-stage malaria infections: immune responses and cytokines involved in protection and pathology / J. Langhorne -- Malaria and the immune system in humans / P. Perlmann -- Genetic regulation of malaria infection in humans / M. Troye-Blomberg -- pt. 4. Malaria vaccines -- Pre-erythrocytic malaria vaccines to prevent Plasmodium flaciparum malaria / W.R. Ballou -- Vaccines against asexual stage malaria parasites / S. Kumar -- Transmission-blocking vaccines / D.C. Kaslow -- Nucleic acid vaccines against malaria / D.L. Doolan -- Antidisease vaccines / L. Schofield -- Adjuvants and malaria vaccine development / L. Xiao -- Malaria vaccine trials / B. Greenwood.
- Malaria methods and protocols 2002, Springer Protocols
- Malaria rapid diagnostic test performance results of WHO product testing of malaria RDTs: round 1 (2008). 2009, WHO
- Manson's Tropical diseases. Twenty-third edition. [23rd ed.] 2014, ScienceDirectFulltext ClinicalKeyFrom the difficult to diagnose to the difficult to treat, Manson's Tropical Diseases prepares you to effectively handle whatever your patients may have contracted. Featuring an internationally recognized editorial team, global contributors, and expert authors, this revised and updated medical reference book provides you with the latest coverage on parasitic and infectious diseases from around the world. Incorporate the latest therapies into your practice, such as recently approved drugs and new treatment options.Find what you need easily and apply it quickly with highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams.
- Medical and veterinary entomology 2002, ScienceDirectEpidemiology of vector-borne diseases / William K. Reisen -- Cockroaches (Blattaria) / Richard J. Brenner -- Lice (Phthiraptera) / Lance A. Durden -- True bugs (Hemiptera) ; Beetles (Coleoptera) / William L. Krinsky -- Fleas (Siphonaptera) / Lance A. Durden, Robert Traub -- Flies (Diptera) / Robert D. Hall, Reid R. Gerhardt -- Moth flies and sand flies (Psychodidae) / Louis C. Rutledge, Raj K. Gupta -- Biting midges (Ceratopogonidae) / Gary R. Mullen -- Black flies (Simuliidae) / Peter H. Adler, John W. McCreadie -- Mosquitoes (Culicidae) / Woodbridge A. Foster, Edward D. Walker -- Horse flies and deer flies (Tabanidae) / Bradley A. Mullens -- Muscid flies (Muscidae) / Roger D. Moon -- Tsetse flies (Glossinidae) / William L. Krinsky -- Myiasis (Muscoidea, Oestroidea) / E. Paul Catts, Gary R. Mullen -- Louse flies, keds, and related flies (Hippoboscoidea) / John E. Lloyd -- Moths and butterflies (Lepidoptera) / Gary R. Mullen -- Ants, wasps, and bees (Hymenoptera) / Roger D. Akre, Hal C. Reed -- Scorpions (Scorpiones) / Gary R. Mullen, Scott A. Stockwell -- Solpugids (Solifugae) ; Spiders (Araneae) / Gary R. Mullen -- Mites (Acari) / Gary R. Mullen, Barry M. OConnor -- Ticks (Ixodida) / Daniel E. Sonenshine, Robert S. Lane, William L. Nicholson.
- Medical microbiology. 7th edition. 2013, ClinicalKeyQuickly learn the microbiology fundamentals you need to know with this 7th Edition, by Dr. Patrick R. Murray, Dr. Ken S. Rosenthal, and Dr. Michael A. Pfaller. Newly reorganized to correspond with integrated curricula and changing study habits, this practical and manageable text is clearly written and easy to use, presenting clinically relevant information about microbes and their diseases in a succinct and engaging manner. Learn the most up-to-date and relevant information in medical microbiology. Study efficiently thanks to a reorganized format that places review chapters at the beginning of each section and review questions at the end of each chapter. Focus on clinical relevance with new interactive case presentations to introduce each of the microbial pathogens that illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Visualize the clinical presentations of infections with new and updated clinical photographs, images, and illustrations.
- Micromammals and macroparasites : who is who and how they interact? / S. Morand ... [et al.] -- Digenean trematodes / C. Feliu ... [et al.] -- Cestodes of small mammals : taxonomy and life cycles / B.B. Georgiev, R.A. Bray and D.T.J. Littlewood -- Nematodes / S. Morand, S. Bouamer and J.-P Hugot -- Acanthocephalans / A. Ribas and J.C. Casanova -- Taxonomy, host associations, life cycles and vectorial importance of ticks parasitizing small mammals / L.A. Durden -- Mesostigmatid mites as parasites of small mammals : systematics, ecology, and the evolution of parasitic associations / A.P.G. Dowling -- Taxonomy, life cycles and the origin of parasitism in trombiculid mites / A.B. Shatrov and J.I. Kudryashova -- Blood-sucking lice (Anoplura) of small mammals : true parasites / K.C. Kim -- Fleas : permanent satellites of small mammals / S.G. Medvedev and B.R. Krasnov -- Bat flies : obligate ectoparasites of bats / C.W. Dick and B.D. Patterson -- Patterns of macroparasite diversity in small mammals / B.R. Krasnov, R. Poulin and S. Morand -- Patterns of host specificity in parasites exploiting small mammals / R. Poulin, B.R. Krasnov and S. Morand -- Coevolution of macroparasites and their small mammalian hosts : cophylogeny and coadaptation / J.-P. Hugot -- Comparative phylogeography : the use of parasites for insights into host history / Cj.M. Nieberding and S. Morand -- Insularity and micromammal-macroparasite relationships / E. Magnanou and S. Morand -- Models for host-macroparasite interactions in micromammals / R. Rosà ... [et al.] -- Transmission ecology and the structure of parasite communities /aI.M. Cattadori ... [et al.] -- Effect of macroparasites on the energy budget of small mammals / A.A. Degen -- Immunogenetics of micromammal-macroparasite interactions / N. Charbonnel, J. Goüy de Bellocq and S. Morand -- Interactions among immune, endocrine, and behavioural response to infection / Z.M. Weil, L.B. Martin II and R.J. Nelson -- Behaviour, life history strategies and parasite infection in rodents / C.J. Barnard and J.M. Behnke -- Nematode zoonoses / J.C. Casanova, A. Ribas and J.M. Segovia -- Rodents as definitive hosts of Schistosoma, with special reference to S. mansoni transmission / J.-M. Duplantier and M. Sene -- Towards understanding the impacts of environmental variation on Echinococcus multilocularis transmission / D.R.J. Pleydell ... [et al.] -- Parasites and pest population management / H. Leirs and G.R. Singleton -- Biological conservation and parasitism / P. Christe, S. Morand and J. Michaux -- Global changes and the future of micromammal-macroparasite interactions / S. Morand, R. Poulin and B.R. Krasnov.
- Modelling parasite transmission and control 2010, SpringerProgress in modelling malaria transmission -- Vector transmission heterogeneity and the population dynamics and control of lymphatic filariasis -- Modelling multi-species parasite transmission -- Metapopulation models in tick-borne disease transmission modelling -- Modelling stochastic transmission processes in helminth infections -- Modelling environmentally-mediated infectious diseases of humans: transmission dynamics of schistosomiasis in China -- Parameter estimation and site-specific calibration of disease transmission models -- Modelling malaria population structure and its implications for control -- Mathematical modelling of the epidemiology of tuberculosis -- Modelling trachoma for control programmes -- Transmission models and management of lymphatic filariasis elimination -- Disease transmission models for public health decision-making : designing intervention strategies for Schistosoma japonicum -- Modelling climate change and malaria transmission -- Modelling the transmission of Trypanosoma cruzi : the need for an integrated genetic epidemiological and population genomics approach.
- Molecular detection of human parasitic pathogens 2013, CRCnetBASE"A book on the molecular detection of major human viral, bacterial, fungal, and parasitic pathogens, this text provides coverage of the organisms with an emphasis on the sample preparation and molecular detection procedures. Chapters consist of concise reviews of pathogens in respect to taxonomy, biology, epidemiology, and pathogenesis; a description of a clinical sample collection preparation procedures; a summary of molecular detection methods available; and a discussion on the challenges, limitations, and advantages for current methods. Written for practitioners and students, this textbook is a guide for future development of improved molecular methods for pathogens. Offers an in-depth review of state-of-the-art molecular detection and identification methods for human parasitic pathogens. Provides comprehensive coverage of important human parasitic pathogens. Provides an authoritative summary of biology, epidemiology, and pathogenesis of major human parasitic pathogens. Includes chapter entries written by experts in respective fields of human parasitic pathogen collection"--Provided by publisher.
- Molecular mechanisms of parasite invasion 2008, SpringerCurrent and emerging approaches to studying invasion in apicomplexan parasites / Jeffrey Mital and Gary E. Ward -- Microneme proteins in apicomplexans / Vern B. Carruthers and Fiona M. Tomley -- Erythrocyte invasion by plasmodium falciparum: multiple ligand-receptor interactions and phenotypic switching / Manoj T. Duraisingh ... [et al.] -- Role of the gp85/trans-sialidase superfamily of glycoproteins in the interaction of trypanosoma cruzi with host structures / Maria Jølia M. Alves and Walter Colli -- Calcium regulation and signaling in apicomplexan parasites / Kisaburo Nagamune ... [et al.] -- Trypanosoma cruzi: parasite and host cell signaling during the invasion process / Nobuko Yoshida and Mauro Cortez -- Host cell actin remodeling in response to cryptosporidium / Steven P. O'Hara ... [et al.] -- Host cell actin remodeling in response to trypanosoma cruzi: trypomastigote versus amastigote entry / Renato A. Mortara ... [et al.] -- Actin/myosin-based gliding motility in apicomplexan parasites / Kai Matuschewski and Herwig Schøler -- Roles of proteases during invasion and egress by plasmodium and toxoplasma / Timothy J. Dowse ... [et al.] -- Roles of naturally occurring protease inhibitors in the modulation of host cell signaling and cellular invasion by trypanosoma cruzi / Julio Scharfstein and Ana Paula C.A. Lima -- Biogenesis of and activities at the toxoplasma gondii parasitophorous vacuole membrane / Anthony P. Sinai. The role of host cell lysosomes in trypanosoma cruzi invasion / G. Adam Mott and Barbara A. Burleigh -- Leishmania invasion and phagosome biogenesis / Robert Lodge and Albert Descoteaux -- Plasmodium sporozoite passage across the sinusoidal cell layer / Ute Frevert ... [et al.] -- Transepithelial migration by toxoplasma / Antonio Barragan and Niclas Hitziger -- The microsporidian polar tube and its role in invasion / Frederic Delbac and Valerie Polonais -- Intestinal invasion by entamoeba histolytica / Shahram Solaymani-Mohammadi and William A. Petri, Jr.
- Molecular medical parasitology 2003, ScienceDirectSect. I. Molecular Biology -- Ch. 1. Parasite genomics -- Ch. 2. RNA processing in parasitic organisms: trans-splicing and RNA editing -- Ch. 3. Transcription -- Ch. 4. Post-transcriptional regulation -- Ch. 5. Antigenic variation in African trypanosomes and malaria -- Ch. 6. Genetic and genomic approaches to the analysis of leishmania virulence -- Sect. II. Biochemistry and Cell Biology: Protozoa -- Ch. 7. Energy metabolism -- Ch. 8. Amino acid and protein metabolism -- Ch. 9. Purine and pyrimidine transport and metabolism -- Ch. 10. Trypanosomatid surface and secreted carbohydrates -- Ch. 11. Intracellular signaling -- Ch. 12. Plastids, mitochondria, and hydrogenosomes -- Sect. III. Biochemistry and Cell Biology: Helminths -- Ch. 13. Helminth surfaces: structural, molecular and functional properties -- Ch. 14. Carbohydrate and energy metabolism in parasitic helminths -- Ch. 15. Neurotransmitters -- Sect. IV. Medical Applications -- Ch. 16. Drug resistance in parasites -- Ch. 17. Medical implications of molecular parasitology.
- Why the investigation was started -- Materials and methodology -- Evidence not recorded on videotape -- The phenomenon of the disappearing hair follicles -- Particles entering the eyes -- Particles exiting the eyes -- A substance that transverses the optic globe -- The irregular iris -- Particles that exit the feet -- Particles that enter the feet -- The microorganism mobility : an internal propulsion system -- Green feet illuminate the role of the epidermis in the life-cycle of the microorganism -- Coated hairs under the microscope -- The micro organism possibly growing on a piece of cocaine -- A summary of the observations -- The structure of the microorganism -- A model accounting for the observed phenomena -- Is there a cure? -- Future considerations : a microorganism as an etiology for delusional parasitosis.
- Neuroparasitology and tropical neurology 2013, ScienceDirect"Neuroparasitology and Tropical Neurology, a new volume in The Handbook of Clinical Neurology, provides a comprehensive and contemporary reference on parasitic infections of the human nervous system. Parasitic infections are varied and some are resolved by the host's immune system, other infections may become established even though unnoticed, and some cause severe disease and death. In our modern world, neuroparasitoses are no longer geographically isolated and these infections now appear worldwide. Outside of a very few well understood pathologies, most parasitic infections have been neglected in the neurological literature and most neurologists have never diagnosed such an infection. This volume details how, with the advent of modern neuroimaging techniques, improved diagnostic applications of molecular biology, more accurate immunodiagnosis, and minimally invasive neurosurgery, human nervous system parasitoses are now diagnosed and treated, with increasing frequency. The book is divided into six sections, and begins with an introduction to the mechanisms of infection, diagnosis, and pathology of parasitic diseases. Subsequent chapters detail protozoan diseases and a section covering each of the major classes of human-infecting helminths: nematodes (roundworms), trematodes (flukes), and cestodes (tapeworms). The final section contains chapters on other important areas of tropical clinical medicine including the neurological complications of venomous bites and tropical nutritional deficiencies. Neuroparasitology and Tropical Neurology will be of interest to neurologists, neurosurgeons and other health professionals encountering patients with parasitic infections"--Publisher's description.
- Receptor-based discovery strategies for insecticides and parasiticides: a review / Debra Woods ... [et al.] -- Nonpeptide ligands for peptidergic G protein-coupled receptors / Timothy G. Geary -- Interaction of mimetic analogs of insect kinin neuropeptides with arthropod receptors / Ronald J. Nachman and Patricia V. Pietrantonio -- Neuropeptides in helminths: occurrence and distribution / Nikki J. Marks and Aaron G. Maule -- Neuropeptide physiology in helminths / Angela Mousley ... [et al.] -- Neuropeptide gene families in Caenorhabditis elegans / Chris Li and Kyuhyung Kim -- Control of nematode parasites with agents acting on neuromusculature systems: lessons for neuropeptide ligand discovery / Richard J. Martin and Alan P. Robertson -- Neuropeptide signaling in insects / Miriam Altstein and Dick R. Nassel -- Neuropeptide physiology in insects / William G. Bendena -- Neuropeptide biology in Drosophila / Elke Clynen ... [et al.] -- Neuropeptide receptors as possible targets for development of insect pest control agents / Matthias B. Van Hiel ... [et al.].
- Parasitoid viruses symbionts and pathogens. 1st ed. 2012, ScienceDirect"Parasitoids are parasitic insects that kill their insect hosts in immature pre-reproductive stages. Parasitoids are employed in biological control programs worldwide to kill insect pests and are environmentally safe and benign alternatives to chemical pesticides. As resistance to chemical pesticides continues to escalate in many pest populations, attention is now refocusing on biologically based strategies to control pest species in agriculture and forestry as well as insect vector populations that transmit human and animal diseases. Parasitoids are an economically critical element in this equation and in integrated pest management. Viruses have evolved intimate associations with parasitoids, and this book features a large section on symbiotic viruses that are integrated into the wasp chromosomal DNA (polydnaviruses). A separate section on parasitoid venoms, which are of interest to the pharmaceutical and medical communities as well as insect-oriented biologists, is also featured"--Back cover.
- Parasitology research monographs v. 1-, 2011-, Springer
- This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites.
- Pharmacological potential of selected natural compounds in the control of parasitic diseases 2013, SpringerThe natural world with a large number of terrestrial and marine plants and lower organisms is a great source of bioactive compounds historically used as remedies in various diseases. Within the last decade, such compounds became more attractive targets for pharmacologists and the pharmaceutical industry in drug development projects. This volume presents the pharmacological potential of chemically defined natural compounds obtained from plants, fungi, algae and cyanobacteria with antiparasitic activity, that have been tested against various endo-parasitic protozoan and helminth species. --Source other than Library of Congress.
- Physician's guide to arthropods of medical importance. 5th ed. 2007, CRCnetBASE
- Principles of medicine in Africa. 4th ed. 2013, Cambridge"Principles of Medicine in Africa combines classical clinical medicine with a rich understanding of the major environmental and cultural influences on health and disease, providing comprehensive guidance for anyone intending to practise medicine in Africa. Disease is presented in the context of family and culture, and the effects of inequality and problems of limited resources are addressed."--Excerpt from publisher notes.
- Progress in parasitology 2011, Springer50 years German Society of Parasitology (DGP) (1961-2010) / Johannes Eckert -- Parasitology of the German Democratic Republic (1961-1990) : memories of a time witness / Theodor Hiepe -- Parasites and their world records in their fight for survival / Heinz Mehlhorn -- Cryptosporidium parvum : the veterinary perspective / Arwid Daugschies -- Neonatal porcine coccidiosis / Hanna Lucia Worliczek and Anja Joachim -- Post-translational modifications in apicomplexan parasites / Esther Jortzik, Sebastian Kehr, and Katja Becker -- Development of the RTS, S/AS vaccine candidate from concept to phase III / Joe Cohen ... [et al.] -- Small ruminant theileriosis / Jabbar Ahmed ... [et al.] -- Interactions of Trypanosoma cruzi and triatomines / Günter A. Schaub, Christian K. Meiser, and Carsten Balczun -- Sex in schistosomes -- signaling mechanisms in the female gonads / Svenja Beckmann ... [et al.] -- Anisakid nematode (Ascaridoidea) life cycles and distribution : increasing zoonotic potential in the time of climate change? / Sven Klimpel and Harry W. Palm -- Fish parasites as biological indicators in a changing world : can we monitor environmental impact and climate change? / Harry W. Palm -- Infectious diseases under the influence of changing environmental factors / Franz J. Conraths and Thomas C. Mettenleiter -- Arthropod vectors and their growing importance in Europe / Helge Kampen and Doreen Werner -- A look at the world of ticks / Trevor N. Petney ... [et al.] -- What else besides TBE and borreliosis? : tick-transmitted pathogens in Germany and beyond / Silvia Pluta ... [et al.] -- Tick-borne encephalitis : from microfocus to human disease / G. Dobler ... [et al.].
- Schistosomes and schistosomiasis in South Asia 2012, SpringerIntroduction -- The schistosomes -- The snail -- Prevalence in final host -- Immunological studies -- Disease manifestation and pathology -- Parasitological diagnosis -- Immunodiagnosis -- Chemotherapy -- Control -- Laboratory models developed -- Technologies developed.
- Sustaining the drive to overcome the global impact of neglected tropical diseases second WHO report on neglected tropical diseases. 2013, WHO"The second WHO report builds on the growing sense of optimism generated by the 2012 publication of the WHO roadmap. Commitments on the part of ministries of health in endemic countries, global health initiatives, funding agencies and philanthropists have escalated since 2010, as have donations of medicines from pharmaceutical companies and the engagement of the scientific community. This report marks a new phase and assesses opportunities and obstacles in the control, elimination and eradication of several of these diseases. Unprecedented progress over the past two years has revealed unprecedented needs for refinements in control strategies, and new technical tools and protocols. The substantial increases in donations of medicines made since the previous report call for innovations that simplify and refine delivery strategies. However, some diseases, including especially deadly ones like human African trypanosomiasis and visceral Leishmaniasis, remain extremely difficult and costly to treat. The control of Buruli ulcer, Chagas disease and yaws is hampered by imperfect technical tools, although recent developments for yaws look promising. The report highlights progress against these especially challenging diseases, being made through the development of innovative and intensive management strategies. innovations in vector control deserve more attention as playing a key part in reducing transmission and disease burden, especially for dengue, Chagas disease and the Leishmaniases. Achieving universal health coverage with essential health interventions for neglected tropical diseases will be a powerful equalizer that abolishes distinctions between the rich and the poor, the young and the old, ethnic groups, and women and men."--P. 4 of cover.
- Toxoplasma gondii the model apicomplexan - perspectives and methods. 2nd edition. 2014, ScienceDirectThis book reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism.
- Travel and tropical medicine manual. 4th ed. 2008, ClinicalKeyHere₂s a handy, portable guide to preventing, evaluating, and managing diseases that can be acquired in tropical environments and foreign countries! Whether you₂re a physician, traveler, or both, this respected manual is your perfect source for quick, easy access to the latest travel medicine information. New updates and additional material are presented in a sleek new design that offers rapid access to the content you need. The fourth edition features more critical content than ever before--including new evidence-based recommendations and new maps and illustrations. From pre-travel advice and immunizations to the diagnosis and treatment of a full range of travel-related illnesses, you₂ll have all the information you need to avoid, recognize, and treat illnesses acquired away from home in a convenient, pocket size guide. Illustrates key concepts with visual guidance from dynamic new images. Offers evidence-based treatment recommendations to enable you to manage diseases confidently. Provides access to need-to-know information quickly in a convenient, pocket size for excellent portability. Features 7 major sections, color-coded for quick answers: Pre-travel Advice Advice for Special Travelers Fever Diarrhea Skin Lesions Sexually Transmitted Diseases Worms.
- Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.
- This book intensively examines the efficacy of plant-derived products that have been used for over a thousand years by practitioners of so-called Traditional Chinese Medicine in the light of recent chemotherapeuticals. The chapters were written by renowned Chinese medical researchers and are supplemented by results obtained in German antiparasitic research projects. Parasites and emerging diseases are a major threat of our time, which is characterized by an enormous increase in the size of the human population and by an unbelievably rapid globalization that has led to the daily transport of millions of humans and containers with goods from one end of the earth to the other. Furthermore the slow but constant global warming offers new opportunities for many agents of diseases to become established in new areas. Therefore it is essential that we develop precautions in order to avoid epidemics or even pandemics in overcrowded megacities or at the large-scale farm animal confinements that are needed to secure a steady flow of food in the crowded regions of the world. Of course intensive research in the field of chemotherapy since 1900 has produced unbelievable breakthroughs in therapies for formerly untreatable and thus deadly diseases. However, a large number of untreatable diseases remain, as well as a constantly growing number of agents of disease that have developed resistances to standard chemical compounds.
- Tropical infectious diseases principles, pathogens, and practice. 3rd ed. 2011, ScienceDirectFulltext ClinicalKeyTropical Infectious Diseases: Principles, Pathogens and Practice, by Drs. Richard L. Guerrant, David H. Walker, and Peter F. Weller, delivers the expert, encyclopedic guidance you need to overcome the toughest clinical challenges in diagnosing and treating diseases caused by infectious agents from tropical regions. Sweeping updates to this 3rd edition include vaccines, SARS, hepatitis A-E, Crimean-Congo hemorrhagic fever virus, tick-borne encephalitis and Omsk hemorrhagic fever, human papilloma virus, and mucormycosis. New full-color images throughout allow you to more accurately view the clinical manifestations of each disease and better visualize the life cycles of infectious agents. And, full-text online access at www.expertconsult.com enables you to perform quick searches and rapidly locate and download images. Definitive, state-of-the-art coverage of pathophysiology as well as clinical management makes this the reference you'll want to consult - online and in print - whenever you are confronted with tropical infections, whether familiar or unfamiliar! Obtain complete and trustworthy advice from hundreds of the leading experts on tropical diseases worldwide, including cutting-edge summaries of pathophysiology and epidemiology as well as clinical management.
- Trypanosomes and trypanosomiasis 2014, SpringerCell Biology for Immune Evasion: Organizing Antigenic Variation, Surfaces, Trafficking, and Cellular Structures in Trypanosoma brucei / Ka Fai Leung, Paul T. Manna, Cordula Boehm, Luke Maishman and Mark C. Field -- The Biology of Tsetse-Trypanosome Interactions / Guy Caljon, Linda De Vooght and Jan Van Den Abbeele -- Withstanding the Challenges of Host Immunity: Antigenic Variation and the Trypanosome Surface Coat / James Peter John Hall and Lindsey Plenderleith -- Bridging Innate and Adaptive Immunity in African Trypanosomiasis / John M. Mansfield, Donna M. Paulnock and Gina M. Hedberg -- Adaptive Immunity and Trypanosomiasis-Driven B-Cell Destruction / Stefan Magez and Magdalena Radwanska -- Normal Human Serum Lysis of Non-human Trypanosomes and Resistance of T. b. rhodesiense and T. b. gambiense / Paul Capewell, Caroline Clucas, William Weir, Nicola Veitch and Annette MacLeod -- Proteomics and African Trypanosomes: Shedding New Light on Host-Vector-Parasite Interactions and Impact on Control Methods / Philippe Holzmuller, Pascal Grébaut and Anne Geiger -- Diagnosis of African Trypanosomiasis / Philippe Büscher -- Progress Towards New Treatments for Human African Trypanosomiasis / Jose A. Garcia-Salcedo, Jane C. Munday, Juan D. Unciti-Broceta and Harry P. de Koning -- Animal African Trypanosomosis in Sub-Saharan Africa and Beyond African Borders / Boniface Namangala and Steven Odongo -- Trypanosoma (Duttonella) vivax and Typanosomosis in Latin America: Secadera/Huequera/Cacho Hueco / Mary Isabel Gonzatti, Bernardo González-Baradat, Pedro M. Aso and Armando Reyna-Bello.
- Viruses essential agents of life 2012, Springer"Viruses are now considered to play major roles in the evolution of life. Because they have genes that are not found in any cellular organism they seem to be remnants of early stages of life on earth. Besides their disease causing features and actions as genetic parasites viruses have lifestyles that are clearly symbiotic and even symbiogenetic. Increasing empirical data suggest that some viruses such as endogenous retroviruses and non-retroviral RNA viruses and even DNA viruses prefer cellular genomes as habitat. They determine genetic host (group) identity and genetic host features. Viruses and virus-related modules such as mobile genetic elements and other repeat sequences identified in intronic regions of host genomes play important roles in gene regulation and genetic content (re)arrangement. This book exemplifies some astonishing key features of viruses acting as essential agents of life."--Publisher.
- Working to overcome the global impact of neglected tropical diseases first WHO report on neglected tropical diseases. 2010, WHO"Neglected tropical diseases (NTDs) blight the lives of a billion people worldwide and threaten the health of millions more. These ancient companions of poverty weaken impoverished populations, frustrate the achievement of health in the Millennium Development Goals and impede global development outcomes. A more reliable evaluation of their significance to public health and economies has convinced governments, donors, the pharmaceutical industry and other agencies, including nongovernmental organizations (NGOs), to invest in preventing and controlling this diverse group of diseases. Global efforts to control "hidden" diseases, such as dracunculiasis (guinea-worm disease), leprosy, schistosomiasis, lymphatic filariasis and yaws, have yielded progressive health gains including the imminent eradication of dracunculiasis. Since 1989 (when most endemic countries began reporting monthly from each endemic village), the number of new dracunculiasis cases has fallen from 892 055 in 12 endemic countries to 3190 in 4 countries in 2009, a decrease of more than 99%. The World Health Organization (WHO) recommends five public-health strategies for the prevention and control of NTDs: preventive chemotherapy; intensified case-management; vector control; the provision of safe water, sanitation and hygiene; and veterinary public health (that is, applying veterinary sciences to ensure the health and well-being of humans). Although one approach may predominate for control of a specific disease or group of diseases, evidence suggests that more effective control results when all five approaches are combined and delivered locally." - p. vii
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