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Substance-Related Disorders

  • The Principles of addiction medicine / Duncan Raistrick -- Substitute prescribing : opioid-specific prescribing / Kim Wolff -- Substitute prescribing : buprenorphine maintenance prescribing / Nick Lintzeris -- Treatment of withdrawal symptoms / Joanna Banbery -- Replacement prescribing / Kim Wolff -- Management of comorbidity / Duncan Raistrick -- Toxicologic issues / Kim Wolff -- Medical aspects of drug abuse / Shoshana Zevin and Neal L. Benowitz -- Emergency management of drug abuse / Brett A. Roth, Neal L. Benowitz, and Kent R. Olson.
  • This book attempts to "bridge the gap between the explosion of neuroscientific and behavioral knowledge in the past three decades and treatment delivery in clinical practice. As such, it should fulfill the role of a comprehensive textbook that integrates addiction medicine from its scientific underpinnings to the treatment of patients in clinical settings"--Preface, p. vii.
  • What is addiction neuroethics and why does it matter? -- Brain Imaging in Addiction -- Molecular Neuroscience and Genetics -- Treating Opioid Dependence with Opioids: Exploring the Ethics -- Addiction Neuroscience and Tobacco Control -- Emerging Neurobiological Treatments of Addiction: Ethical and Public Policy Considerations -- Technical, Ethical and Social Issues in the Bioprediction of Addiction Liability and Treatment Response -- Autonomy, Responsibility and the Oscillation of Preference -- Consent and Coercion in Addiction Treatment -- Toward a Lay Descriptive Account of Identity in Addiction Neuroethics -- The Impact of Changes in Neuroscience and Research Ethics on the Intellectual History of Addiction Research -- The Diction of Addiction at the Intersection of Law and Neuroscience -- Social Epistemology: Communicating Neuroscience -- Population Approaches to Alcohol, Tobacco and Drugs: Effectiveness, Ethics and Interplay with Addiction Neuroscience -- Legal Regulation of Addictive Substances and Addiction -- Investment and Vested Interests in Neuroscience Research of Addiction: Ethical Research Requires More than Informed Consent -- Private and Public Approaches to Addiction Treatment: Evidence and Beliefs.
  • Addiction Recovery Management: Theory, Research, and Practice is the first book on the recovery management approach to addiction treatment and post-treatment support services. Distinctive in combining theory, research, and practice within the same text, this ground-breaking title includes authors who are the major theoreticians, researchers, systems administrators, clinicians and recovery advocates who have developed the model. State-of-the art and the definitive text on the topic, Addiction Recovery Management: Theory, Research, and Practice is mandatory reading for clinicians and all professionals who work with patients in recovery or who are interested in the field.
  • "While there is a wealth of published information on addiction medicine, the psychological aspects of alcohol abuse, and behavioral medicine with regard to addiction, virtually none of the existing resources were written with the primary care provider in mind. Addressing Unhealthy Alcohol Use in Primary Care is a handy reference for primary care clinicians who are confronted by patients with these problems daily, and who wish to successfully address these issues in their practice. Focusing on the literature and science relevant to practicing providers, this book covers the range of interventions appropriate for this setting. Topics include assessment, brief counseling interventions, pharmacotherapy, referrals to both specialty care and Alcoholics Anonymous (and other self-help programs), psychiatric comorbidity and other drug use, and other information specific to the needs of the primary care clinician. The vast majority of people with health risks and consequences related to alcohol use receive little to no attention from healthcare, despite the fact that alcohol is a leading cause of early preventable death. This book is a guide to identifying and addressing unhealthy alcohol use in hopes of improving the lives of patients."--publisher's website
  • 1 A Selected Social History of the Stepping-Stone Drugs / Thomas P. Gullotta 1 -- 2 A Biological/Genetic Perspective: The Addicted Brain / Thomas H. Kelly, Alessandra N. Kazura, Karen M. Lommel, Shanna Babalonis, Catherine A. Martin 15 -- 3 Individual Characteristics and Needs Associated with Substance Misuse of Adolescents and Young Adults in Addiction Treatment / Michael L. Dennis, Michelle K. White, Melissa L. Ives 45 -- 4 Adolescent Substance Abuse Treatment: A Review of Evidence-Based Research / Ken C. Winters, Andria M. Botzet, Tamara Fahnhorst, Randy Stinchfield, Rachel Koskey 73 -- 5 Adolescent Outpatient Treatment / Richard Dembo, Randolph D. Muck 97 -- 6 Evidence-Based Family Treatment of Adolescent Substance Abuse and Dependence / Shaun I. Calix, Mark A. Fine 119 -- 7 Residential Treatment of Adolescents with Substance Use Disorders: Evidence-Based Approaches and Best Practice Recommendations / Robert W. Plant, Peter Panzarella 135 -- 8 Primary Prevention in Adolescent Substance Abuse / Martin Bloom, Thomas P. Gullotta 155 -- 9 Religious Involvement and Adolescent Substance Use / Terrence D. Hill, Amy M. Burdette, Michael L. Weiss, Dale D. Chitwood 171 -- 10 School Prevention / Zili Sloboda 191 -- 11 Community Prevention Handbook on Adolescent Substance Abuse Prevention and Treatment: Evidence-Based Practices / Elizabeth J. D'Amico, Matthew Chinman, Stefanie A. Stern, Abraham Wandersman 213 -- Epilogue: The Status of Knowledge Development and the Unknown / Michele Staton-Tindall, Thomas P. Gullotta, William Walton Stoops, Carl G. Leukefeld 251.
  • Advances in animal models of relapse for addiction research / Friedbert Weiss -- Application of chronic extracellular recording method to studies of cocaine self-administration : method and progress / Laura L. Peoples, Alexai V. Kravitz, and Karine Guillem -- Neurochemistry of addiction : monitoring essential neurotransmitters of addiction / Stefan G. Sandberg and Paul A. Garris -- Alcohol craving and relapse prediction : imaging studies / Andreas Heinz ... [et al.] -- Integrating behavioral and molecular approaches in mouse : self-administration studies / Danielle L. Graham and David W. Self -- Neuroeconomics : implications for understanding the neurobiology of addiction / Michael L. Platt ... [et al.].
  • Alcohol and cancer 2011
    The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol{u2019}s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters.
  • "Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism"--Publisher's description.
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    Policy : the principles of service organization and practice / Paul McArdle and Eilish Gilvarry -- Determinants of substance misuse / Paul McArdle -- Drug use in young people : short-term effects and long-term harms / Dan Lubman, Yvonne Bonomo and Murat Yücel -- Young people, substances and harm / Mandy Abbott, Fariah Khan and Eilish Gilvarry -- Trends in substance use and abuse in young people / Cecilia A. Essau and Peter Wennberg -- Substance use and psychiatric comorbidity in children and adolescents / Michael Farrell -- The effectiveness of universal youth substance abuse prevention programmes / David R. Foxcroft, Debby Allen and Lindsey Coombes -- Prevention of substance abuse : targeted approaches / Paul McArdle -- Treatment : course and outcome / Eilish Gilvarry and Giles Hayden -- Legal and ethical issues in the treatment of children and young people / Sarah Woolrich -- Principles of assessment for adolescents with substance use disorders / Oscar G. Bukstein and Theresa Lutka-Fedor -- Assessment instruments and outcome measurement / Oscar G. Bukstein and Theresa Lutka-Fedor -- Biological markers (drugs) / Kim Wolff -- Assessement and management in the emergency department and the paediatric unit / Joan Robson -- Brief alcohol interventions in young people : evidence and applicability / Malathi Natarajan and Eileen Kaner -- Psychological interventions for young people with substance misuse disorders / Gillian Tober -- Empirical and clinical foundations of family-based interventions for adolescent substance abuse / Howard A. Liddle, Cynthia L. Rowe and Gayle A. Dakof -- Pharmacological treatment of adolescent substance use disorder / E. Jane Marshall and K.A.H. Mirza -- The role of primary care in management of substance use/abuse / Clare Gerada -- Integrated treatment of substance use disorders and co-occurring psychiatric disorders in adolescents / Robert D. Davies and Paula D. Riggs.
  • Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.
  • Section I. The basis of addictive disorders -- Neurobiology of addiction -- Genetics of addiction -- Epidemiology of addiction -- Cross-cultural aspects of addiction -- Section II. The nature of treatment -- Science in the treatment of substance abuse -- Assessment of the patient -- Screening and brief intervention -- Patient placement criteria -- "Recovery" in chronic care disease management -- Section III. Specific drugs of abuse -- Neurobiology of alcohol use disorder -- Treatment of alcohol intoxication and alcohol withdrawal -- Neurobiology of stimulants -- Clinical management: cocaine -- Clinical management: methamphetamine -- Hallucinogens and club drugs -- Tobacco use disorder -- Benzodiazepines and other sedatives and hypnotics -- Treatment of anabolic-androgenic steroid-related disorders -- Neurobiology of opiates and opioids -- Opioid detoxification -- Methadone and buprenorphine maintenance -- Opioid antagonists -- Neurobiology of marijuana -- Treatment of cannabis use disorder -- Section IV. Treatment modalities -- Psychodynamic psychotherapy -- Cognitive-behavioral therapies -- Motivational enhancement -- Twelve-step facilitation -- Contingency management -- Network therapy -- Group therapy -- Family therapy -- Section V. Rehabilitation settings -- Inpatient treatment -- Therapeutic communities -- Community-based treatment -- History of alcoholics anonymous and the experiences of patients -- Psychological mechanisms in alcoholics anonymous -- Outcomes research on twelve-step programs -- Section VI. Special populations -- Women and addiction -- Perinatal substance use disorders -- Adolescent substance use disorders: epidemiology, neurobiology, and screening -- Adolescent substance use disorders: transition to substance abuse, prevention, and treatment -- Psychiatric consultation in pain and addiction -- Prevention of prescription drug abuse -- HIV/AIDS and hepatitis C -- Substance use disorders among physicians -- Substance use issues among gay, lesbian, bisexual, and transgender people -- Minorities -- Section VII. Special topics -- Testing to identify recent drug use -- Medical education on addiction -- Prevention of substance abuse -- Forensic addiction psychiatry -- Substance abuse and mental illness -- Substance-related and addictive disorders.
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    Part 1 : The basis of addictive disorders -- Neurobiology of addiction / George F. Koob -- Genetics of addiction / Joel Gelernter, Henry R. Kranzler -- Epidemiology of addiction / Judith S. Brook, Kerstin Pahl, Elizabeth Rubenstone -- Cross-cultural aspects of addiction / Nady el-Guebaly -- Part 2 : The nature of treatment -- Assessment of the patient / Shelly F. Greenfield, Grace Hennessy -- Patient placement criteria / David Mee-Lee, David R. Gastfriend -- Evolution in addiction treatment concepts and methods / A. Thomas McLellan -- Part 3 : Specific drugs of abuse -- Alcohol -- Neurobiology of alcohol / Clifford M. Knapp, Domenic A. Ciraulo, Henry R. Kranzler -- Clinical management of alcohol abuse and dependence / Hugh Myrick, Tara Wright -- Stimulants -- Neurobiology of stimulants / Margaret Haney -- Clinical management : cocaine / Thomas R. Kosten, Mehmet Sofuoglu, Tracie J. Gardner -- Clinical management : methamphetamine / Richard A. Rawson, Walter Ling -- Hallucinogens and club drugs -- Neurobiology of hallucinogens / Richard A. Glennon -- Hallucinogens and club drugs / Michael F. Weaver, Sidney H. Schnoll -- Other substances -- Nicotine and tobacco / Tony P. George, Andrea H. Weinberger -- Benzodiazepines and other sedatives and hypnotics / Adam Bisaga -- Treatment of anabolic-androgenic steroid-related disorders / Harrison G. Pope, Jr., Kirk J. Brower -- Opioids -- Neurobiology of opiates and opioids / Mary Jeanne Kreek -- Detoxification of opioids / Soteri Polydorou, Herbert D. Kleber -- Opioid maintenance treatment / Richard S. Schottenfeld -- Buprenorphine maintenance / Eric C. Strain, Michelle R. Lofwall -- Antagonists of opioids / Charles O'Brien, Kyle M. Kampman -- Part 4 : Treatment modalities -- Psychodynamics / Hallie A. Lightdale, Avram H. Mack, Richard J. Frances -- Cognitive-behavioral therapies / Kathleen M. Carroll -- Motivational enhancement / Carlo C. DiClemente, Miranda Garay, Leigh Gemmell -- Twelve-step facilitation / Richard K. Ries, Marc Galanter, J. Scott Tonigan -- Contingency management / Stephen T. Higgins, Kenneth Silverman -- Network therapy / Marc Galanter -- Group therapy / David W. Brook -- Family therapy / Timothy J. O'Farrell, William Fals-Stewart -- Part 5 : Rehabilitation settings -- Inpatient treatment / Roger D. Weiss, Jennifer Sharpe Potter, Rocco A. Iannucci -- Therapeutic communities / George De Leon -- Community-based treatment / Jonathan I. Ritvo, Harvey L. Causey III -- Alcoholics anonymous and other 12-step programs -- Psychological mechanisms in alcoholics anonymous / J. Scott Tonigan, Gerard J. Connors -- The history of alcoholics anonymous and the experiences of patients / Edgar P. Nace -- Outcome research on 12-step and other self-help programs / Rudolf H. Moos, Christine Timko -- Part 6 : Special populations -- Adolescent substance abuse / Yifrah Kaminer -- The mentally ill substance abuser / Stephen Ross -- Women and addiction / Kathleen T. Brady, Sudie E. Back -- Perinatal substance abuse / Loretta P. Finnegan, Stephen R. Kandall -- HIV/AIDS and hepatitis C / Steven L. Batki, Kalpana I. Nathan -- Prescription drug abuse / Wilson M. Compton, Richard Denisco -- Substance use disorders among physicians / J. Wesley Boyd, John R. Knight -- Gay men and lesbians / Robert Paul Cabaj -- Minorities / Joseph Westermeyer, Daniel Dickerson -- Part 7 : Special topics -- Testing to identify recent drug use / Robert L. DuPont, Carl M. Selavka -- Medical education / Erik W. Gunderson, Frances R. Levin, Petros Levounis -- Prevention of substance abuse / Richard R. Clayton, Melissa J.H. Segress, Crystal A. Caudill -- Forensic addiction psychiatry / Avram H. Mack, Monica Barros.
  • Also available: Print – 1998
  • Animal models of drug addiction 2011
    Springer Protocols
    Intracranial self-stimulation / Styliani Vlachou and Athina Markou -- Stimulant self-administration / Leigh V. Panlilio -- Opiate self-administration / Francesco Leri -- Nicotine self-administration / Robert E. Sorge and Paul B.S. Clarke -- Alcohol self-administration / Friedbert Weiss -- Place conditioning / Christopher L. Cunningham, Peter A. Groblewski, and Charlene M. Voorhees -- Sensitization / Jessica A. Loweth and Paul Vezina -- Animal models of eating disorders / Stephanie D. Hancock and Mary C. Olmstead -- Acquisition of drug self-administration / Marilyn E. Carroll and Richard A. Meisch -- Escalation of drug use / Serge H. Ahmed -- Environmental modulation of drug taking / Aldo Badiani ... [et al.] -- Craving / Jeffrey W. Grimm -- Habit formation and compulsion / David Belin ... [et al.] -- Impulsivity / Andrea Bari, Trevor W. Robbins, and Jeffrey W. Dalley -- Binge drug taking / Herbert E. Covington, III and Klaus A. Miczek -- Withdrawal / Alasdair M. Barr, Heidi N. Boyda, and Ric M. Procyshyn -- Relapse / Suzanne Erb and Franca Placenza.
  • Theoretical issues -- Epidemiological perspectives on co-occurring anxiety disorder and substance use disorder -- The neurobiology of anxiety: potential for co-morbidity of anxiety and substance use disorders -- Research findings -- Posttraumatic stress disorder and substance use disorder: neuroimaging, neuroendocrine, and psychophysiological findings -- Co-morbidity of social phobia and alcohol use disorders: a review of psychopathology research findings -- Panic spectrum disorders and substance use -- Treatment strategies -- Treatment of co-morbid obsessive-compulsive disorder and substance use disorders -- Treatment for co-morbid posttraumatic stress disorder and substance use disorders -- Treatment of co-occurring alcoholism and social anxiety disorder -- Treating co-morbid panic disorder and substance use disorder -- Cognitive- behavioral treatment of co-morbid panic psychopathology and tobacco use and dependence -- Personality-based approaches to treatment of co-morbid anxiety and substance use disorder -- Medical management of co-morbid anxiety and substance use disorder -- Integration and conclusions -- Anxiety disorder and substance use disorder co-morbidity: common themes and future directions.
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    Assessment of addictive behaviors for relapse prevention / Dennis M. Donovan -- Assessment of addictive behaviors in ethnic-minority cultures / Arthur W. Blume, Osvaldo F. Morera, and Berenice Garcia -- Assessment of alcohol problems / Ned L. Cooney, Ronald M. Kadden, Howard R. Steinberg -- Assessment of smoking behavior / William G. Shadel and Saul Shiffman -- Assessment of cocaine abuse and dependence / Kathleen M. Carroll and Samuel A. Ball -- Assessment of amphetamine abuse and dependence / Richard A. Rawson, Ruthlyn Sodano, and Maureen Hillhouse -- Assessment of opioid use / James Westphal, David A. Wasserman, Carmen L. Masson, and James L. Sorensen -- Assessment of cannibus use disorders / Robert S. Stephens and Roger A. Roffman -- Assessment of club drug, hallucinogen, inhalant, and steroid abuse and dependence / Jason R. Kilmer, Rebekka S. Palmer, and Jessica M. Cronce -- Assessment of eating behaviors / R. Lorriane Collins -- Assessment of gambling behaviors / Howard J. Shaffer and Christopher R. Freed -- Assessment of sex offender relapse / Jennifer G. Wheeler, William H. George, and Kari Stephens -- Assessment of sexual risk behaviors / William H. George, Tina M. Zawacki, Jane M. Simoni, Kari A. Stephens, and Kristen P. Lindgren.
  • Part I. Mechanistic Aspects Underlying Alcoholism -- Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit Disorder / George F. Koob -- Synaptic Effects Induced by Alcohol / David M. Lovinger and Marisa Roberto -- Signaling Pathways Mediating Alcohol Effects / Dorit Ron and Robert O. Messing -- Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Access Points / Bo Söderpalm and Mia Ericson -- What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol / Gerald A. Deehan Jr., Mark S. Brodie and Zachary A. Rodd -- Part II. Genetics -- Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models / John C. Crabbe, Kenneth S. Kendler and Robert J. Hitzemann -- Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental Factors / Christina S. Barr -- Genetically Selected Alcohol Preferring Rats to Model Human -- Alcoholism / Roberto Ciccocioppo -- Advanced Transgenic Approaches to Understand Alcohol-Related Phenotypes in Animals / Ainhoa Bilbao -- Part III. Clinical Phenotypes and Preclinical Models Thereof Modeling Alcohol Self-Administration in the Human Laboratory / Ulrich S. Zimmermann, Sean O'Connor and Vijay A. Ramchandani -- Animal Models of Excessive Alcohol Consumption in Rodents / Howard C. Becker -- Modeling Relapse Situations in the Human Laboratory / Rajita Sinha -- Modeling Relapse in Animals / Rémi Martin-Fardon and Friedbert Weiss -- Invertebrate Models of Alcoholism / Henrike Scholz and Julie A. Mustard -- Part IV. Novel Insights from Brain Imaging The Dopamine System in Mediating Alcohol Effects in Humans / K. Charlet, A. Beck and A. Heinz -- Stimulant and Sedative Effects of Alcohol / Reuben A. Hendler, Vijay A. Ramchandani, Jodi Gilman and Daniel W. Hommer -- Chronic Alcohol Consumption, Abstinence and Relapse: Brain Proton Magnetic Resonance Spectroscopy Studies in Animals and Humans / Dieter J. Meyerhoff, Timothy C. Durazzo and Gabriele Ende -- Part V. Translational Aspects and Medication Development -- Translational Approaches to Medication Development / Selena Bartlett and Markus Heilig -- New Pharmacological Treatment Strategies for Relapse Prevention / Rainer Spanagel and Valentina Vengeliene -- The Challenge of Studying Parallel Behaviors in Humans and Animal Models / David N. Stephens, Hans S. Crombag and Theodora Duka -- A Translational Approach to Novel Medication Development for Protracted Abstinence / Barbara J. Mason and Amanda E. Higley -- New Approaches to Addiction Treatment Based on Learning and Memory / Falk Kiefer and Christina Dinter -- Adolescent Substance Misuse: Neurobiology and Evidence-Based Interventions / Nicola C. Newton, Maeve O'Leary-Barrett and Patricia J. Conrod -- Deep Brain Stimulation as a Therapy for Alcohol Addiction / Thomas F. Münte, Hans-Jochen Heinze and Veerle Visser-Vandewalle.
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    Ethical foundations of substance abuse treatment / Cynthia M.A. Geppert, Laura Weiss Roberts -- The therapeutic relationship in substance abuse treatment / Jennifer Knapp Manuel, Alyssa A. Forcehimes -- The ethics of harm reduction / William R. Miller -- Ethical issues in the treatment of persons with co-occurring disorders / Christie A. Cline, Kenneth Minkoff -- Cultural and spiritual dimensions of addiction treatment / Kamilla L. Venner, Michael P. Bogenschutz -- Forensic issues in the treatment of addictions / Joseph B. Layde -- Ethical issues in the treatment of women with substance abuse / Diane T. Castillo, Ann Waldorf -- Ethical aspects of the treatment of substance abuse in children and adolescents / Jerald Belitz -- Ethical dilemmas in treating chronic pain in the context of addiction / Joanna G. Katzman, Cynthia M.A. Geppert.
  • Ch. 1. Hydrocarbons -- ch. 2. Alcohols and phytosterols -- ch. 3. Aldehydes and ketones -- ch. 4. Carboxylic acids -- ch. 5. Esters -- ch. 6. Lactones -- ch. 7. Anhydrides -- ch. 8. Carbohydrates and their derivatives -- ch. 9. Phenols and quinones -- ch. 10. Ethers -- ch. 11. Nitriles -- ch. 12. Acyclic amines -- ch. 13. Amides -- ch. 14. Imides -- ch. 15. N-nitrosamines -- ch. 16. Nitroalkanes, nitroarenes, and nitrophenols -- ch. 17. Nitrogen heterocyclic components -- ch. 18. Miscellaneous components -- ch. 19. Fixed and variable gases -- ch. 20. Metallic and nonmetallic elements, isotopes, ions, and salts -- ch. 21. Pesticides and growth regulators -- ch. 22. Genes, nucleotides, and enzymes -- ch. 23. Hoffmann analytes -- ch. 24. Tobacco and/or tobacco smoke components used as tobacco ingredients -- ch. 25. Pyrolysis -- ch. 26. Carcinogens, tumorigens, and mutagens vs. anticarcinogens, inhibitors, and antimutagens -- ch. 27. Free radicals -- ch. 28. Summary.
  • Patients with chronic pain understandably seek relief from their distress and discomfort, but many medications that alleviate pain are potentially addictive, and most chronic pain conditions only have a temporary response to opiate analgesic drugs. This volume reviews the fundamental topics that underlie the complex relationships of this controversial domain. The authors review behavioral models and practical methods for understanding and treating chronic pain and addiction including methods to formulate patients with complex comorbidity and screen patients with chronic pain for addictive liability. Finally, the authors describe the current findings from clinical and basic science that illuminate the role of opiates, cannabinoids and ketamine in the treatment of chronic pain. Up to date and comprehensive, this book is relevant to all professionals engaged in the care of patients with chronic pain or addiction and all others interested in these contemporary issues, particularly non-clinicians seeking clarity in the controversy over the best approach to patients with chronic pain.
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    Author David Sheff offers a new paradigm for dealing with addiction based on cutting-edge research and stories of his own and other families' struggles with--and triumphs over--drug abuse. "Addiction is a preventable, treatable disease, not a moral failing. As with other illnesses, the approaches most likely to work are based on science -- not on faith, tradition, contrition, or wishful thinking. These facts are the foundation of Clean, a myth-shattering look at drug abuse by the author of Beautiful Boy. Based on the latest research in psychology, neuroscience, and medicine, Clean is a leap beyond the traditional approaches to prevention and treatment of addiction and the mental illnesses that usually accompany it. The existing treatment system, including Twelve Step programs and rehabs, has helped some, but it has failed to help many more, and David Sheff explains why. He spent time with scores of scientists, doctors, counselors, and addicts and their families to learn how addiction works and what can effectively treat it. Clean offers clear, cogent counsel for parents and others who want to prevent drug problems and for addicts and their loved ones no matter what stage of the illness they're in. But it is also a book for all of us -- a powerful rethinking of the greatest public health challenge of our time."-- Book jacket.
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  • The volume presents current material on the key neurobiological and genetic elements in an individual's susceptibility to drug dependence as well as the processes by which some individuals proceed from casual drug use to drug dependence. Chapters describe and explain the neurobiological mechanisms of drug use and drug addiction. The development and use of animal models to study neurochemical, molecular and cellular brain mechanisms are described and illustrated. Other chapters discuss the effects of drug use on memory, decision-making, and the developing brain (especially in adolescents).
  • Volume 3, Intervention for Addictions, provides chapters on psychosocial treatments, pharmacological treatments, provision of health care to addicted individuals, prevention, and public policy issues. Basically, this volume contains the practical application of the information in Volumes 1 and 2. Overall, this volume provides a detailed picture of the myriad of science-based interventions available for the treatment of addiction. With the expanding growth of neurobiological research newer and more effective pharmacological treatments should be available on the near horizon.
  • Also available: Print – v. 1-3, 2005.
    Part I. General aspects of alcohol toxicity, consumption, and disease -- Part II. Damage/disease: -- General aspects of pathology -- Organ damage -- Cells, pathways, interactions, processes -- Part III. Selective methods used in alcohol research -- Index.
  • Pt. 1. Pharmacological-based models of addiction -- pt. 2. Neurocomputational models of addiction -- pt. 3. Economic-based models of addiction.
  • This book provides a comprehensive, state of the art overview covering both the diagnosis and the treatment of dual disorders ? joint psychiatric and substance use disorders ? in a way that is highly relevant to clinical work and the organization of care systems. It is designed to meet the real need for a European perspective on dual disorders, taking into account the realities of European treatment organization. All chapters have been written by European authors on the basis of existing European treatment programs or guidelines and European research. Dual disorders are increasingly encountered by health professionals working in mental health and addiction care, and they represent a formidable challenge for caregivers, care organizations, and society as a whole. During the past decade, various approaches and programs have been designed to challenge the traditional gap between addiction treatment and mental health care. The overwhelming majority of the programs, however, have emanated from the United States. Given the vast differences between the European and U.S. health contexts, it can be questioned whether these American-oriented treatment programs are of value in European countries. Co-occurring Addictive and Psychiatric Disorders ? A Practice-Based Handbook from a European Perspective therefore represents a timely and much-needed addition to literature on the subject.
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    Report 1. Medicaid hospital costs -- Report 2. Medicare hospital costs.
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    Mental disorders / Steven Hyman ... [et al.] -- Neurological disorders / Vijay Chandra ... [et al.] -- Learning and developmental disabilities / Maureen S. Durkin ... [et al.] -- Alcohol / Jürgen Rehm ... [et al.] -- Illicit opiate abuse / Wayne Hall ... [et al.].
  • Criminalistics: introduction to controlled substances / Joseph P. Bono -- Pathology of drug abuse / edited by Charles V. Wetli -- Pharmacokinetics: drug absorption, distribution, and elimination / Amanda J. Jenkins -- Pharmacodynamics / edited by Stephen J. Heishman -- Alcohol / edited by Alan Wayne Jones -- Neurochemistry of drug abuse / edited by Julie K. Staley and Kelly P. Cosgrove -- Addiction medicine / edited by Kim Wolff -- Medical complications of drug abuse / edited by Neal L. Benowitz -- Sports / edited by Marc D. Bollmann and Martial Saugy -- Workplace testing / edited by Yale H. Caplan and Marilyn A. Huestis -- Point of collection drug testing / edited by Dennis J. Crouch -- Post-mortem toxicology / edited by Henrik Druid -- Toxicogenetics / edited by Steven B. Karch -- Drug law -- Appendices.
  • Drug addiction v. 1-4, 1972-74.
    Print Material
    v. 1. Experimental pharmacology -- v. 2. Clinical and socio-legal aspects -- v. 3. Neurobiology and influences on behaviour -- v. 4. New aspects of analytical and clinical toxicology.
  • Depressants -- Alcoholism: an introduction -- Alcoholism: acute treatment -- Stimulants: amphetamines and cocaine -- Opioids and other analgesics -- Cannabinols -- Hallucinogens and related drugs -- Glues, inhalants and aeorsols -- Over-the-counter (OTC) drugs and some prescription drugs -- Xanthines (caffeine) and nicotine -- Multidrug abuse and dependence -- Emergency problems: a quick overview -- Rehabilitation.
  • Etiological theories on the relationship of mental disorders and substance use disorders / Moggi, F. -- The genetic basis of substance use and abuse / Jacobson, K.C. -- Paths of genetic and environmental influence: the routes connecting personality disorders with substance use disorders / Cadoret, R.J. ... [et al.] -- Historical and conceptual issues / Jacobs, W.S., Cahill, K.S., Gold, M.S. -- Comorbidity in alcohol use disorders: focus on mood, anxiety and personality / Hintz, T., Mann, K. -- Having attention-deficit/hyperactivity disorder and substance use disorder: a review of the literature / Eich, D., Figner, B. -- Diagnostic issues in dual diagnosis patients / Petitjean, S. -- Neurocognitive impairment: an underdiagnosed comorbid entity in the treatment of substance use disorders / Dorsteler-MacFarland, K.M., Cereghetti, K.H., Wiesbeck, G.A. -- Modified therapeutic communities for co-occurring substance abuse and psychiatric disorders / Leon, G.D.
  • Eating disorders, addictions, and substance use disorders are each challenging in their own right, but they also commonly co-occur, causing major challenges for clinicians. Emerging research suggests that there are common substrates at the neuroanatomical, neurochemical, and psychological levels. While randomized controlled trials have revealed a number of effective psychotherapeutic and psychopharmacologic treatments for the individual conditions, little is known about integrative interventions for these comorbidities. This book presents cutting-edge research on the overlap of these complex disorders and reviews integrative assessment strategies and treatment approaches, including enhanced cognitive behavioral therapy, dialectical behavior therapy, abstinence approaches, motivational enhancement, mindfulness meditation, and pharmacotherapy. The issue of whether eating-disordered behaviors such as dieting, binge eating, and excessive exercise are merely other forms of addictive behavior is examined. The authors argue both for and against the concept of food addiction in research, clinical treatment, and public policy.
  • Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetic.
  • Also available: Print – 2011
    Introduction to the guidelines. Purpose, target and scope -- Background -- A dual obligation, a quadruple imperative -- Indispensability of controlled medicines in contemporary medical practices -- Safety of controlled medicines -- Current availability -- Impediments to availability, accessibility and affordability -- Why and how to work with this document? -- Guidelines for ensuring balance in national policies on controlled substances. Content of drug control legislation and policy -- Authorities and their role in the system -- Policy planning for availability and accessibility -- Healthcare professionals -- Estimates and statistics -- Procurement -- Other -- Country assessment checklist.
  • Defining and measuring drug abusing behaviors / Zili Sloboda -- Drug abuse heterogeneity and the search for subtypes / Meyer D. Glantz, Devin P. Conway and James D. Colliver -- Studying the natural history of drug use / Yih-Ing Hser ... [et al.] -- Health, social and psychological consequences of drug use and abuse / Michael D. Newcomb and Thomas Locke -- Use of archival data / Zili Sloboda, Rebecca McKetin and Nicholas J. Kozel -- Sampling issues in drug epidemiology / Colin Taylor and Paul Griffiths -- Collecting drug use data from different populations / Edward M. Adlaf -- Indirect methods to estimate prevalence / Matthew Hickman and Colin Taylor -- Qualitative methods in the drug abuse field / Claire E. Sterk and Kirk W. Elifson -- Ethical considerations for drug abuse epidemiologic research / Craig L. Fry and Wayne Hall -- A common language for a common problems: the developing role of drug epidemiology in a global context / Paul Griffiths and Rebecca McKetin -- Longitudinal studies of drug use and abuse / Thomas A. Wills, Carmella Walker and Jody A. Resko -- Drug abuse and the spread of infection: HIV and AIDS as an example / Don C. Des Jarlais, Holly Hagan and Samuel R. Friedman -- Implications of epidemiologic information for effective drug abuse prevention strategies / Zili Sloboda -- The role of treatment data in studying the epidemiology of substance use and abuse / Robert L. Hubbard.
  • The addictions treatment field is currently undergoing a period of increased scrutiny, upheaval and change. The growing emphasis on treatment accountability and cost effectiveness is leading to major changes in standards of care. Inconsistent practices based solely on clinical intuition rather than hard scientific evidence of treatment efficacy are rapidly becoming unacceptable. Translating science-based treatments into clinical settings is an important priority in the addictions field and has been the subject of an influential Institute of Medicine report. Substance abuse treatment programs.
  • Fetal alcohol spectrum disorder: ethical, legal and moral implications associated with the rights of the unborn child -- Why People with FASD Fall for Manipulative Ploys: Ethical Limits of Interrogators? Use of Lies -- Neurodevelopmental Disorder associated with Prenatal Alcohol Exposure: Consumer Protection and the Industry?s Duty to Warn -- Experience in Involuntary Hospitalisation of Drug and Alcohol Addicted Mothers during Their Pregnancies at Borgestadklinikken, Norway -- Is it ethical to condone low levels of drinking in pregnancy? -- Ethical challenges when screening for and diagnosing FASD in adults -- Neurocognitive Difficulties Underlying High Risk and Criminal Behaviour in FASD: Clinical Implications -- Medico-legal interventions in management of offenders with Fetal Alcohol Spectrum Disorders (FASD) -- Oral language and communication factors to consider when supporting people with FASD involved with the legal system -- Evolution of the Diagnosis of Fetal Alcohol Spectrum Disorder: From DSM-IV-TR to DSM-5: The Justice System in the United States ? Time for a Paradigm Shift! -- Smart Justice and FASD in Alaska: From Prevention to Sentence Mitigation. .
  • Measuring acute alcohol impairment / Christopher S. Martin -- Update on clinical and forensic analysis of alcohol / Alan Wayne Jones and Derrick J. Pounder -- Post-mortem alcohol: aspects of interpretation / Derrick J. Pounder and Alan Wayne Jones -- Recent advances in biochemical tests for acute and chronic alcohol consumption / Anders Helander and Alan Wayne Jones -- Alcohol determination in point of collection testing / J. Robert Zettl.
  • PART 1: THEORY -- Addiction in Perspective -- Dangerous Consumptions -- Overview of this Book -- Companion Relationships -- A Social World -- Worlds, Paradigms and Assumptions -- The Particle Paradigm -- The Social Paradigm -- Switching to a Social World -- Addiction and Connecting -- Connecting to the World -- Patterns of Fragmentation -- Responding to Addiction -- The Prospect of Change -- Setting Out and Setting Back -- Making it Stick -- PART 2: PROCESSES -- Becoming Intimate -- Living in Relationships -- Intimacy and the "Four Cs" -- Special Considerations -- Quality Intimacy? -- Intimacies in Addictive Contexts -- Intimacy within Addictive Relationships -- Intimacies for Others -- Systems of Intimate Connections -- Intimacy and Power -- Controlling Tactics -- The Myth of Disinhibition -- Violence as a Social Event -- Managed Intimacy -- PART 3: FAMILIES & COMMUNITIES -- Fragmented Lives -- Fragmenting Environments -- How Intimates Respond -- Broader Social Dynamics -- Collective Opportunities -- Empowerment and Connectedness -- Reconnecting Intimates -- Responsibility for Change -- Change Processes -- Guidelines for Effective Collective Action -- Reintegration -- What is Reintegration? -- Six Phases of Reintegration -- Reforming Intimacies -- Enabling Closeness and Compassion -- Domains of Connectedness -- PART 4: APPLICATIONS -- Family Resources -- Social Resources from Inner Power -- Social Resources Offered by Services -- Mobilizing Communities -- Volunteer Networks -- Croatian/Italian Community Clubs -- An Indigenous Approach -- Applications to Practice -- Barriers to Social Inclusive Practice -- Social Engagement -- Social Assessment -- Facilitative Meetings -- Looking Ahead -- Where It Fits -- Future Opportunities
  • Also available: Print – 2010
    "This publication contributes to the scientific understanding of gender, women, and tobacco in the context of efforts to control the global tobacco epidemic. Topics covered include determinants of starting to use tobacco; exposure to second-hand smoke; the impact that tobacco use has on health; addiction and cessation; treatment programs; and gender and human rights policy. The publication also addresses national economic policy with regard to tobacco control, international treaties, and strategies for tobacco-free mobilization at the regional and international levels. Special attention is paid to an analysis of policies that affect girls and women throughout the life course. Men's responsibility to protect women against second-hand smoke is also highlighted"--Publisher's description.
  • "The manner in which genetic research associated with addiction is conducted, interpreted and translated into clinical practice and policy initiatives raises important social, ethical and legal issues. Genetic Research on Addiction fulfils two key aims; the first is to identify the ethical issues and requirements arising when carrying out genetically-based addiction research, and the second is to explore the ethical, legal and public policy implications of interpreting, translating and applying this research. The book describes research guidelines on human protection issues such as improving the informed consent process, protecting privacy, responsibilities to minors and determining whether to accept industry funding. The broader public health policy implications of the research are explored and guidelines offered for developing effective social interventions. Highly relevant for clinicians, researchers, academics and policy-makers in the fields of addiction, mental health and public policy"--Provided by publisher.
  • Also available: Print – 2011
    "This publication presents a comprehensive perspective on the worldwide, regional and country consumption of alcohol, patterns of drinking, health consequences and policy responses in member states. It represents a continuing effort by WHO to support member states with global information in their efforts to reduce the harmful use of alcohol and its health and social consequences"--Publisher's description.
  • Also available: Print – 2014
    The Global status report on alcohol and health 2014 presents a comprehensive perspective on the global, regional and country consumption of alcohol, patterns of drinking, health consequences and policy responses in Member States. It represents a continuing effort by the World Health Organization (WHO) to support Member States in collecting information in order to assist them in their efforts to reduce the harmful use of alcohol, and its health and social consequences. The report was launched in Geneva on Monday 12 May 2014 during the second meeting of the global network of WHO national counterparts for implementation of the global strategy to reduce the harmful use of alcohol.--Publisher's description.
  • Also available: Print – 2010
    The global strategy to reduce the harmful use of alcohol. Setting the scene -- Challenges and opportunities -- Aims and opportunities -- Guiding principles -- National policies and measures -- Policy options and interventions -- Global action : key roles and components -- Implementing the strategy -- Resolution of the sixty-third World Health Assembly (May 2010) WHA63.13 Global Strategy to Reduce the Harmful Use of Alcohol.
  • Also available: Print – 2009
    These guidelines review the use of medicines such as methadone, buprenorphine, naltrexone and clonidine in combination with psychosocial support in the treatment of people dependent on heroin or other opioids. Based on systematic reviews of the literature and using the GRADE approach to determining evidence quality, the guidelines contain specific recommendations on the range of issues faced in organizing treatment systems, managing treatment programs and in treating people dependent on opioids.--back cover
  • I: HISTORICAL OVERVIEW: The emerging science of drug abuse prevention / William J. Bukoski -- II: SOCIAL CONTEXTS OF PREVENTION: Effective mass media strategies for drug abuse prevention campaigns / Philip Palmgreen and Lewis Donohew -- Drug abuse prevention curricula in schools / Gilbert J. Botvin and Kenneth W. Griffin -- Dissemination of research-based family intervention for the prevention of substance abuse / Karol L. Kumpfer and Steve Adler -- Peers and the prevention of adolescent drug use -- / E. R. Oetting and R. S. Lynch -- Mobilizing communities to reduce risk for drug abuse: a comparison of two strategies / Michael W. Arthur, Charles D. Ayers, Kelly A. Graham, and J. David Hawkins -- Community-focused drug abuse prevention / Barry M. Kibel and Harold D.Holder -- Drug abuse prevention in the workplace / Royer F. Cook -- Prevention approaches to methadone treatment settings: children of drug abuse treatment clients / Richard F. Catalano, Kevin P. Haggerty, and Randy R. Gainey -- III: PREVENTION AS SOCIAL CONTROL: Drug tests in prevention research / Robert L. DuPont and Keith E. Saylor -- Anti-drug-abuse policies on prevention strategies / Mary Ann Pentz -- IV: THEORETICAL AND EMPIRICAL FOUNDATIONS OF PREVENTION: Forging a relationship between drug abuse epidemiology and drug abuse prevention / Zili Sloboda -- Risk and protective factors of adolescent drug use: implications for prevention programs / Judith S. Brook. David W. Brook, Linda Richter, and Martin Whiteman -- Bridging the gap between substance use prevention theory and practice / Brian R. Flay and John Petraitis -- Preventive intervention targeting precursors / John E. Lochman -- Designing prevention programs: the developmental perspective / Marvin W. Berkowitz and Audrey L. Begun -- V: SPECIAL POPULATIONS: Gender issues in substance abuse prevention / Louise Ann Rohrbach and Joel Milam -- Preventing substance use among Latino youth / Charles R. Martinez, Jr., J. Mark Eddy, and David S. DeGarmo -- African-American substance use epidemiology and prevention issues / William L. Turner and Michael J. Hench -- The effectiveness of alcohol and drug abuse prevention among American-Indian youth / Fred Beauvais and Joseph E. Trimble -- Drug abuse prevention research for Asian and Pacific Islander Americans / W. William Chen -- VI: INTERACTIONS BETWEEN BIOLOGY AND SOCIAL CONTEXT: RISKS FOR MULTIPLE BEHAVIORAL AND MENTAL DISORDERS: Basic science and drug abuse prevention: neuroscience, learning, and personality perspectives / Michael T. Bardo, Thomas Kelly, Donald R. Lynam, and Richard Milich -- Cross-national comparisons of co-morbidities between substance use disorders and mental disorders / Ronald C. Kessler, Sergio Aguilar-Gaxiola, Laura Andrade, Rob Bijl ... [et al.] -- Drug abuse research for high-risk youth / Leona L. Eggert and Brooke P. Randell -- Research designs for family studies / Michael Vanyukov, Howard Moss, and Ralph E. Tarter -- VII: RESEARCH DESIGN, MEASUREMENT, AND DATA ANALYTIC ISSUES: Design principles and their application in preventive field trials / C. Hendricks Brown -- Major data analysis issues in drug abuse prevention research / David P. MacKinnon and James H. Dwyer -- Metholological considerations to prevention research / Linda M. Collins and Brian P. Flaherty -- Prevention program implementation / Steven Schinke and Kristin Cole -- Family management practices: research design and measurement issues / Thomas J. Dishion, Bert Burraston, and Fuzhong Li -- Power analysis models and methods: a latent variable framework for power estimation and analysis / Terry E. Duncan, Susan C. Duncan, and Puzhong Li -- VIII: DRUG ABUSE PREVENTION: A LOOK TO THE FUTURE: Application of computer technology to drug abuse prevention / Kris Bosworth -- Putting science into practice / Gale Held.
  • Introduction to therapeutic drug monitoring. -- Monitoring free drug concentration. -- Analytical techniques for measuring concentrations of therapeutic drugs in biological fluids. -- The pre-analytical phase of drug testing: from specimen collection to analysis. -- Effect of hemolysis, high bilirubin, lipemia, paraproteins, and system factors on therapeutic drug monitoring. -- Digoxin: so many interferences and how to eliminate them. -- Interferences with measurement of anticonvulsants. -- Pitfalls in measuring antidepressant drugs. -- Immunosuppressive drugs: pharmacokinetics, preanalytic variables, and analytical considerations. -- Therapeutic drug monitoring in human immunodeficiency virus/acquired immunodeficiency syndrome. -- Pharmacogenetics and personalized medicine: issues and methodology. -- Interference of heterophilic and other antibodies in measurement of therapeutic drugs by immunoassays. -- Drug-herb and drug-food interactions: impact on therapeutic drug monitoring. -- Toxic element testing with clinical specimens. -- Alcohol testing. -- Introduction to drugs of abuse testing. -- Urinary adulterants and drugs of abuse testing. -- Hair, oral fluid, sweat, and meconium testing for drugs of abuse: advantages and pitfalls. -- Abused and designer drugs and how they escape detection. -- Interpretation of amphetamines screening and confirmation testing. -- Clinical false-positive drug test results. -- Providing expert witness for alcohol and positive drugs of abuse test results.
  • "Modern imaging techniques have allowed researchers to non-invasively peer into the human brain and investigate, among many other things, the acute effects and long-term consequences of drug abuse. Here, we review the most commonly used and some emerging imaging techniques in addiction research, explain how the various techniques generate their characteristic images and describe the rational that researchers use to interpret them. In addition, examples of seminal imaging findings are highlighted that illustrate the contribution of each imaging modality to the expansion in our understanding of the neurobiological bases of drug abuse and addiction, and how they can be parlayed in the future into clinical and therapeutic applications"--Provided by publisher.
  • Part I: Introduction -- Part II: Neurobehavioral approaches for understanding inhibitory control -- Part III: Translating research on inhibitory control to at-risk populations -- PartIV: Translating research on inhibitory control to prevention interventions -- PartV: Conclusion.
  • A collection of syntheses of the international scientific literature and recommendations on public health problems, by Inserm's expert advisory groups.
  • Cocaine -- Natural stimulants -- Synthetic stimulants -- Hallucinogens -- Opiates and opioids -- Dissociative anesthetics -- Anabolic steroids -- Solvents -- Marijuana -- Appendix 1: Conversion formulas -- Appendix 2: Blood alcohol concentrations -- Appendix 3: Volume of distribution calculations -- Appendix 4: Normal heart weights.
  • "A comprehensive, authoritative text on all aspects of substance abuse and addiction medicine. Scientific topics such as the biology of various addictions and all dimensions of clinical treatment and management are addressed by a wide range of leading contributors. Behavioral addictions are addressed also, so the text is not solely devoted to specific substances and their misuse"--Provided by publisher.
  • This text will provide readers with a thorough review of the complex condition of chronic pain and addictions. The book was originally commissioned due to the need in the field for more literature on the topic. This concise pocket book will review epidemiology, clinical features, diagnosis, and medical management of both chronic pain and addiction. Busy healthcare professionals will benefit from this text, which will not only cover the foundation of the management of both conditions and together, but discuss up-to-date national and international treatment guidelines, upcoming therapies and REMS.
  • L'abuso di sostanze può essere alla base di un gran numero di patologie e disturbi psichiatrici, e viene classificato tra i primi quattro fattori di rischio che contribuiscono al carico di malattia globale. Una situazione di dipendenza può infatti complicare un quadro psichiatrico già difficile, poiché si sovrappone ad altri disturbi e talvolta ne prende le forme, rendendo ancora più ardua la valutazione del paziente. Individuare con precisione un disturbo da abuso di sostanze può facilitare la diagnosi clinica, evitare test non necessari e abbreviare la durata del ricovero. Questo volume costituisce una guida pratica e concisa rivolta agli studenti, ai medici e ad altre figure professionali che si confrontano con la moderna medicina della dipendenza. Illustrando una vasta gamma di evidenze, metodi e soluzioni per la gestione del paziente con dipendenza, questa guida fornisce gli strumenti e le conoscenze di base utili a una pratica clinica rapida ed efficace in questo campo.
  • Also available: Print – 2010
    The mhGAP-IG has been developed through an intensive process of evidence review. A WHO Guideline Development Group of international experts conducted systematic reviews to develop evidence-based recommendations. The recommendations were then converted into clearly presented stepwise interventions and then circulated among a wider range of reviewers across the world to include all the diverse contributions. The mhGAP-IG is based on the mhGAP Guidelines on interventions for mental, neurological and substance use disorders (http:// Both documents will be reviewed and updated in 5 years. Any revision and update before that will be made to the online version of the document.--(excerpt, p. 1).
  • Humans are biologically programmed to seek out pleasurable experiences. These experiences are processed in the mesolimbic system, also referred to as the "reward center" of the brain, where a number of chemical messengers work in concert to provide a net release of dopamine in the Nucleus Accumbens. In some genetically predisposed individuals, addiction occurs when the mechanisms of the mesolimbic system are disrupted by the use of various drugs of abuse. Since Alcoholics Anonymous was founded in 1935, it's 12 step program of spiritual and character development has helped countless alcoholics and drug addicts curb their self-destructive behaviors. However, the program was developed at a time when comparatively little was known about the function of the brain and it has never been studied scientifically. This is the first book to take a systematic look at the molecular neurobiology associated with each of the 12 steps and to review the significant body of addiction research literature that is pertinent to the program.
  • This title draws upon research on the drug widely believed to form the basis of tobacco use and dependence, nicotine. When discussing drug addiction and dependence, an increasing number of scientists are using the concepts of motivation and related constructs and their applications in modifying behavior.
  • Also available: Print – 2000
    Also available: Print – <2002>
  • Rapid advances in understanding neural-immune interactions have far reaching impact on research in many areas of neuroscience. It is becoming increasingly clear that neuroimmune factors modulate a wide range of brain functions and play an important role in development, normal brain function, and CNS dysfunctions, including neurodegenerative diseases, neuropsychiatric disorders and addiction. "Neural.Immune Interaction in Brain Function and Alcohol Related Disorders" integrates emerging knowledge on neural-immune interactions with related key discoveries in alcohol research to provide a comprehensive overview of neuroimmune system in brain function and behavior associated with alcohol use disorders. Readers will benefit from cutting edge insights provided by outstanding, active researchers in the fields of neuroimmune research and alcohol use disorders.
  • The primary purpose of this book and its companion volume The Neuropharmacology of Nicotine Dependence is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While the present volume considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the book The Neuropharmacology of Nicotine Dependence focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers with a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of research and will hopefully prove valuable to those who are developing their own research programmes in this important topic. CTBN Vol 23 The Behavioral Genetics of Nicotine and Tobacco The primary purpose of this book and its companion volume The Neuropharmacology of Nicotine Dependence is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While the present volume considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the book The Neuropharmacology of Nicotine Dependence focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers with a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of research and will hopefully prove valuable to those who are developing their own research programmes in this important topic.
  • Neurobiology of addiction 2006
    What is addiction? -- Animal models of drug addiction -- Psychostimulants -- Opioids -- Alcohol -- Nicotine -- Cannabinoids -- Imaging -- Neurobiological theories of addiction -- Drug addiction : transition from neuroadaptation to pathophysiology.
  • The dopamine transporter and addiction / William M. Meil and John W. Boja -- Neurochemistry of nicotine dependence / Darlene H. Brunzell -- Neurochemical substrates of habitual tobacco smoking / Irina Esterlis, Suchitra Krishnan-Sarin, and Julie K. Staley -- Neurochemical and neurobehavioral consequences of methamphetamine abuse / Colin N. Haile -- Neurochemical adaptations and cocaine dependence / Kelly P. Cosgrove and Julie K. Staley -- Neuropsychiatric consequences of chronic cocaine abuse / Deborah C. Mash -- Neurobiology of 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") / Michael H. Baumann and Richard B. Rothman.
  • This book reviews the imaging features associated with selected classes of pharmaceuticals and drugs on brain, head and neck, and spine and explains the implications of the imaging findings for the neuroradiologist and the clinician. Some agents produce characteristic abnormalities with distinctive imaging features, while others have a spectrum of manifestations on imaging. Still further agents produce rather nonspecific changes on imaging, requiring a differential diagnosis. In this book, informative cases are depicted by rich images, with concise accompanying explanatory text that reviews the class of agent and the mechanism of action and discusses image interpretation and its significance.
  • Imaging Tobacco Smoking with PET and SPECT -- Behavioral Mechanisms Underlying Nicotine Reinforcement -- The Role of Mesoaccumbens Dopamine in Nicotine Dependence -- Nicotine Withdrawal -- Neurobiologal bases of cue- and nicotine-induced reinstatement of nicotine seeking -- Psychiatric disorders as vulnerability factors for nicotine addiction: What have we learned from animal models?.
  • Also available: Print – 1988
  • NIDA research monograph v. 5-40, 42, 44-54, 56-121, 123-143, 145-159, 161-170, 172-177, 1976-82, 1984-98.
  • The criminalistics of controlled substances / Joseph P. Bono -- Overview of pathology of drug abuse : scene of death and the autopsy / Charles V. Wetli -- Heart disease / Renu Virmani, Allen P. Burke, Andrew Farb -- Vascular effects of substance abuse / Frank D. Kolodgie, Allen P. Burke, Jagat Narula, Florabel G. Mullick, Renu Virmani -- Myocardial alterations in drug abusers / Steven B. Karch -- Valvular heart disease / Michael D. Bell -- Lung disease / Michael D. Bell -- Disorders of the central nervous system / Michael D. Bell -- Toxicogenetics in drug abuse : pharmacogenomics for toxicology / Robert M. White, Steven H.Y. Wong -- Toxicogenetics in drug abuse : heritable channelopathies and myopathies / Kathryn A. Glatter, Jonica Calkins, Sanjay J. Ayirookuzhi.
  • Ch. 1. Pharmacogenomics principles of alcohol and DOA / Christine L.H. Snozek and Loralie J. Langman -- ch. 2. Alcohol : use and abuse / Amitava Dasgupta -- ch. 3. Slate and trait makers of alcohol abuse / Joshua Bornhorst ... [et al.] -- ch. 4. Introduction to drugs of abuse / Larry Broussard and Catherine Hammett-Stabler -- ch. 5. Pharmacogenomics of amphetamine and related drugs / Steven C. Kazmierczak -- ch. 6. Pharmacogenomics of cocaine / Loralie J. Langman and Christine L.H. Snozek -- ch. 7. Genetic aspect of marijuana metabolism and abuse / Pradip Datta -- ch. 8. Genetic aspect of opiate metabolism and addiction / Jorge L. Sepulveda -- ch. 9. Pharmacogenomics aspects of addiction treatment / F. Gerard Moeller -- ch. 10. Methodologies in pharmacogenetics testing / Jorge L. Sepulveda.

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