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  • "This overview outlines the statutory background for WHO's research, identifies the milestones in health research over five decades, and discusses issues of both process and programs. This report also includes accounts of regional efforts in health research"--Publisher's description. African region; Eastern Mediterranean region; European region; South East Asia region; Western Pacific region; Pan American Health Organization
  • It has become increasingly accepted that important digital data must be retained and shared in order to preserve and promote knowledge, advance research in and across all disciplines of scholarly endeavor, and maximize the return on investment of public funds. To meet this challenge, colleges and universities are adding data services to existing infrastructures by drawing on the expertise of information professionals who are already involved in the acquisition, management and preservation of data in their daily jobs. Data services include planning and implementing good data management practices, thereby increasing researchers' ability to compete for grant funding and ensuring that data collections with continuing value are preserved for reuse. This volume provides a framework to guide information professionals in academic libraries, presses, and data centers through the process of managing research data from the planning stages through the life of a grant project and beyond. It illustrates principles of good practice with use-case examples and illuminates promising data service models through case studies of innovative, successful projects and collaborations.
  • Research in Clinical Practice is a neat, pocket-sized reference guide examining how to get the most from actively participating in research. Including how to begin, avoiding pitfalls, whom to approach and what questions to ask - all significant practicalities for conducting research in the reader's area of interest. Each reader will learn how to make the best use of such a valuable time. Written by two experienced surgeons, both of whom achieved post graduate research degrees, Research in Clinical Practice, is an essential tool for clinicians embarking on a research project as well as those who are new to supervising researchers.
  • Topics include self-Management, self-Efficacy, health Status, and some diabetes-specific scales.
  • Part One: Beginning grantsmanship -- 1. The NIH and other sources of research support -- 2. A strong proposal -- 3. Proposal review -- 4. The R01 research grant -- 5. The abstract and specific aims -- 6. Background and significance -- 7. Preliminary studies -- 8. Research design and methods -- 9. The budget -- 10. Biographical sketch, research support, and resources -- 11. Human subjects -- 12. Animal subjects -- 13. Consortiums, contracts, consultants, and collaborators -- 14. Literature cited and appendixes -- 15. Revision of an unfunded proposal -- 16. Competing renewal of R01 projects (progress reports) -- 17. Proposal submission and supplementary materials -- 18. Your first grant award (R, F, or K) -- 19. Advice for beginners in academia. -- Part two: Advanced grantsmanship -- 20. Small business grants -- 21. Program project grants (P01) -- 22. Center grants -- 23. Construction grants -- 24. T32 institutional research training program grants -- 25. Instrumentation grants -- Appendix -- A. Information sources: private foundation and government web sites, and study section contacts -- B. Summary statements, reviewer comments, assignment, award, and triage letters -- C. Examples of figures from preliminary data -- D. Examples of design format -- E. Instructions to reviewers concerning human subjects -- F. Suggested reading.
  • "Comprehensive research and a highly trained workforce are essential for the improvement of health and health care both nationally and internationally. Over the past 40 years the National Research Services Award (NRSA) Program has played a large role in training the workforce responsible for dramatic advances in the understanding of various diseases and new insights that have led to more effective and targeted therapies. In spite of this program, the difficulty obtaining jobs after the postdoc period has discouraged many domestic students from pursuing graduate postdoc training. In the United States, more than 50 percent of the postdoc workforce is made up of individuals who obtained their Ph. D.s from other countries. Indeed, one can make a strong argument that the influx of highly trained and creative foreigners has contributed greatly to U.S. science over the past 70 years. Research Training in the Biomedical, Behavioral, and Clinical Research Sciences discusses a number of important issues, including: the job prospects for postdocs completing their training; questions about the continued supply of international postdocs in an increasingly competitive world; the need for equal, excellent training for all graduate students who receive NIH funding; and the need to increase the diversity of trainees. The book recommends improvements in minority recruiting, more rigorous and extensive training in the responsible conduct of research and ethics, increased emphasis on career development, more attention to outcomes, and the requirement for incorporating more quantitative thinking in the biomedical curriculum."--Publisher's description.
  • Scientific research and ethics -- Ethical decision making -- Data acquisition and management -- Mentoring and collaboration -- Collaboration between academia and private industry -- Authorship -- Publication and peer review -- Misconduct in research -- Intellectual property -- Conflicts of interest and scientific objectivity -- The use of animals in research -- The protection of human subjects in research -- Protecting vulnerable human subjects in research -- Genetics, cloning, and stem cell research -- International research.
  • To examine how purchasers and payers interact with the various components of the clinical research enterprise and to understand their perspective on what vision of the enterprise should be.
  • Considerations prior to sample size calculation -- Comparing means -- Large sample tests for proportions -- Exact tests for proportions -- Tests for goodness-of-fit and contingency tables -- Comparing time-to-event data -- Group sequential methods -- Comparing variabilities -- Bioequivalence testing -- Dose response studies -- Microarray studies -- Bayesian sample size calculation -- Nonparametrics -- Sample size calculation in other areas.
  • The book does not focus primarily on grammar, but includes sections on important facets, such as 'voices' and tenses. It also addresses problems associated with writing other texts (reports, reviews, emails, social/professional networking communications etc.). Composed (with inputs from numerous senior scientists) by authors who have written, revised or edited more than 4,000 papers, A Scientific Approach to Scientific Writing will be essential reading for non-native English-speaking students and researchers of all disciplines, and a valuable resource for those with English as a first language."--pub. desc.
  • 1. Introduction -- 2. Scientific training and personal development -- 3. The scientific method -- 4. Attributes required by research scientists -- 5. The impact of managerialism -- 6. Leadership in science -- 7. Insights from notable scientists -- 8. Future challenges for scientific research.
  • Apples or oranges? -- selection of the control group -- Who was left out? exclusions, refusals, and drop-outs -- Mountain or molehill? the clinical importance of the results -- What do the other witnesses say? corroborating vidence -- Do the pieces fit together? systematic overviews and meta-analysis -- What do all these numbers mean? -- Where is the evidence? searching for information.
  • Evidence-based information plays a critical role in clinical practice decisions. Secondary sources are often unreliable; it.s up to the student, then, to critically assess peer-reviewed research literature. Using a highly structured yet accessible method, this text teaches students to critically analyze research from primary sources. Step-by-step approach. learn to recognize a meaningful study, clues to potential study flaws, and ways to apply solid evidence in clinical practice. Simple 6-point framework. learn to evaluate studies in terms of the authors trademark mnemonic device, M.A.A.R.I.E. (Methods, Assignment, Assessment, Results, Interpretation and Extrapolation). Unique Learning Aids - question checklists, real-world scenarious, flaw-catching exercises and more help to make complex concepts easy to grasp.
  • Why write a grant? -- Becoming familiar with funding sources -- Developing your ideas for funding -- Common sections of proposals -- Strategies for effective writing -- Technical writing considerations -- Developing a budget -- Putting it all together to create a budget -- Technical considerations in budget development -- Four project structures -- Understanding the process of collaboration -- Forming a collaborative team -- Learning about your institution -- Electronic considerations -- Understanding the review process -- Responding to the proposal review -- A case study -- Welcome to the world of post-award -- More post-award considerations.
  • Scientific medicine in Miettinen's conception of it is very different from the two ideas about it that came to eminence in the 20th century. To him, medicine is scientific to the extent that it has a rational theoretical framework and a knowledge-base from medical science. He delineates the nature of that theoretical framework and of the research to develop the requisite knowledge for application in such a framework. The knowledge ultimately needed is about diagnostic, etiognostic, and prognostic probabilities, and it necessarily is to be codified in the form of probability functions, embedded in practice-guiding expert systems.
  • Chapter 1. Translational Medicine / Dennis Cosmatos, Shein-Chung Chow -- Chapter 2. Strategic Concepts in Translational Medicine / Dennis Cosmatos, Giora Feuerstein, Shein-Chung Chow -- Chapter 3. Design and Analysis Approaches for Discovery Translational Medicine / Dennis Cosmatos, Shein-Chung Chow (Eds.), Stephen B. Forlow, Jennifer A. Isler, Zhaosheng Lin, Michael E. Burczynski, Jessie Q. Xia, S. Stanley Young -- Chapter 4. Biomarker Development / Mark Chang -- Chapter 5. Targeted Clinical Trials / Jen-pei Liu -- Chapter 6. Statistical Methods in Translational Medicine / Shein-Chung Chow, Siu-Keung Tse, Dennis Cosmatos -- Chapter 7. Nonparametric Methods in Translational Research / Kongming Wang, Shein-Chung Chow -- Chapter 8. Model Selection/Validation / Jen-pei Liu -- Chapter 9. Translation in Clinical Information between Populations-Bridging Studies / Chin-Fu Hsiao, Mey Wang, Herng-Der Chern, Jen-pei Liu -- Chapter 10. Translation in Clinical Technology-Traditional Chinese Medicine / Chin-Fu Hsiao, Hsiao-Hui Tsou, Shein-Chung Chow.
  • Chapter 1. Introduction to Translational Medicine -- Chapter 2. New Light Through an Old Window? The "Translational Turn" in Biomedical Research -- Chapter 3. Translational Medicine -- Drivers and Barriers of TM -- Chapter 5. Developing an Evaluation Model for Translational Medicine Research Programs -- Chapter 6. Emerging Concepts in Biomarker Discovery -- Chapter 7. Imaging Biomarkers for Innovative Drug Development -- Chapter 8. Translational Bioinformatics -- Chapter 9. Exploiting Translational Medicine Through Public- Private Partnerships -- Chapter 10. The Role of the Product Development Partnership as a Translational Mechanism for Delivering Health Solutions in Low- Resource Settings.
  • Understanding Clinical Papers is a popular and well established introduction to reading clinical papers. It unravels the process of evidence-based practice, using real papers to illustrate how to understand and evaluate published research, and provides clear explanations of important research-related topics.
  • Complete how-to guidance on conducting clinical research, this book addresses the operational challenges of clinical trials and provides a clear explanation of the methodologies necessary to interpret results. The book addresses all aspects of clinical trials, from design and implementation to statistics to regulatory scrutiny. A resource for students, residents, and clinicians who need a working knowledge of clinical research principles. The chapter authors are all leaders in the field and engaged in cutting edge clinical research. Use as a textbook, as a reference, and as a course guide for mandated clinical research training courses.
  • This book is organized as a practical guide to writing a biomedical research article. Hence, as you will see from the table of contents, chapters are arranged according to the sequence of tasks that we normally encounter in our writing. The book deals only with writing and submission of manuscripts; there are no directions concerning, for example, the preparation of figures or audiovisual presentations. Furthermore, every chapter is concise; we do not beat topics to death. Exemplars of highly prevalent expressions are given throughout, however the number of examples in the book is not excessive.
  • Introduction to the art and science of clinical research -- What you need to know about clinical research ethics -- What you need to know about the regulation of clinical research -- Designing a clinical research study -- Selecting subjects for clinical studies -- Risks and benefits in clinical research -- Recruiting subjects -- Informed consent -- Privacy and confidentiality -- The "ethics" section -- Procedures and methods -- Statistics, data collection and management, and record keeping -- Use of human biological materials -- Special issues raised by evolving areas of clinical research -- Case histories : learning from experience.
  • "The scientific proposal-writing process can be a daunting experience for graduate students and young researchers. This book covers all aspects of the process, from structure and style to obtaining research grant funding. Organized much like a research proposal, the book covers identifying a research topic, drafting a hypothesis, conducting a literature review, describing methods for data collection and analysis, and presenting the proposal. The final section describes strategies for putting together a winning NIH proposal and responding to reviewer comments. Concepts are illustrated with examples, applications, exercises, and checklists of guidelines"-- Provided by publisher. "Preface For more than 15 years, I have taught a graduate course on grant proposal writing for students in the School of Public Health and Health Sciences at the University of Massachusetts at Amherst. With their encouragement and suggestions, this textbook has come to be a reality. Competition for research funds has never been more intense and, at the same time, the grant application and review process at such agencies as the National Institutes of Health (NIH) are undergoing significant transformation. Writing Dissertation and Grant Proposals: Epidemiology, Preventive Medicine, and Biostatistics is unique in representing an up-to-date textbook targeting effective grant proposal writing in this growing and important field. The text covers all aspects of the proposal-writing process from soup to nuts. Stepby- step tips address grant structure and style alongside broader strategies for developing a research funding portfolio. Throughout, concepts are illustrated with annotated examples from successfully funded proposals in the field. Strategies to avoid common errors and pitfalls (e.g., dos and don'ts) and summary checklists of guidelines are provided. Essentially, the text can be viewed as a virtual cookbook of the appropriate ingredients needed to construct a successful grant proposal. Therefore, this text is not only highly relevant for early-stage investigators including graduate students, medical students/residents, and postdoctoral fellows, but also valuable for more experienced faculty, clinicians, epidemiologists, and other health professionals who cannot seem to break the barrier to NIH-funded research"-- Provided by publisher.
  • "Today, information in a medical article must include not only research activities and findings, but also strategic, managerial, and administrative ones. It might include planning, political, cultural, spiritual and other social aspects as well as experience in healthcare, health protection, disease prevention, and health promotion. This book is designed to help the authors of medical articles communicate better in today's practice and health research environment. It explores the most effective practices for communicating using three medical literature formats: scientific articles, articles where the subject is not based on the scientific method, and business reports"--Provided by publisher.

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