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- Advanced male urethral and genital reconstructive surgery. Second edition [2nd ed.] — Vitrification in assisted reproduction a user's manual (100)
- Yen and Jaffe's Reproductive endocrinology physiology, pathophysiology, and clinical management. 7th ed. — Yen and Jaffe's Reproductive endocrinology physiology, pathophysiology, and clinical management. 7th ed. (1)
- Since the publication of the first edition of Urethral Reconstructive Surgery, important refinements have been added to the urologic surgical armamentarium. Extensively revised and updated, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition guides urologists in a practical manner on how to evaluate and manage complex urethral and male genital reconstructive challenges. Chapters have been added on wound healing, synchronous urethral strictures, non-transecting anastomotic urethroplasty (including muscle and vessel sparing), overlapping buccal grafts, male urethral slings, genital skin grafting, Peyronies surgery, priapism, pediatric strictures, and prosthetics. Such chapters greatly strengthen the overall appeal of the book. The volume closes with a new comprehensive appendix of preferred instruments. With broad contributions by international authorities in reconstructiveurologic surgery, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition is a valuable resource for all urologists, from residents to reconstructive surgeons.
- 1. Scope and goals of andrology / Eberhard Nieschlag -- 2. Physiology of testicular function / Gerhard F. Weinbauer ... [et al.] -- 3. Physiology of sperm maturation and fertilization / Trevor G. Cooper and Ching-Hei Yeung -- 4. Classification of andrological disorders / Frank Tüttelmann and Eberhard Nieschlag -- 5. Anamnesis and physical examination / Eberhard Nieschlag and Hermann M. Behre -- 6. Imaging diagnostics / Hermann M. Behre and Michael Zitzmann -- 7. Endocrine laboratory diagnosis / Manuela Simoni and Eberhard Nieschlag -- 8. Cytogenetic and molecular genetic investigations / Manuela Simoni and Peter Wieacker -- 9. Semen analysis / Trevor G. Cooper -- 10. Sperm quality and function tests / Ching-Hei Yeung and Trevor G. Cooper -- 11. Testicular biopsy and histology / Martin Bergmann and Sabine Kliesch -- 12. Diseases of the hypothalamus and the pituitary gland / Hermann M. Behre ... [et al.] -- 13. Disorders at the testicular level / Eberhard Nieschlag ... [et al.] -- 14. The aging male and late-onset hypogonadism / Claus Rolf, Michael Zitzmann, and Eberhard Nieschlag -- 15. Diseases of the seminal ducts / Hermann M. Behre ... [et al.] -- 16. Disorders of erection, cohabitation, and ejaculation / Hermann van Ahlen and Sabine Kliesch -- 17. Disorders of androgen target organs / Peter F. Wieacker, Hermann M. Behre, and Eberhard Nieschlag -- 18. Testicular dysfunction in systemic diseases / Gideon A. Sartorius and David J. Handelsman -- 19. Environmental influences on male reproductive health / Martin H. Brinkworth and David J. Handelsman -- 20. Gynecology relevant to andrology / Ulrich A. Knuth -- 21. Testosterone therapy / Eberhard Nieschlag and Hermann M. Behre -- 22. Empirical therapies for idiopathic male infertility / Eberhard Nieschlag and Axel Kamischke -- 23. Assisted reproduction / Christian De Geyter, Maria De Geyter, and Hermann M. Behre -- 24. Cryopreservation of human spermatozoa / Sabine Kliesch ... [et al.] -- 25. Psychology of fertility disorders / Regina Oberpenning, Fritz A. Muthny, and Frank Oberpenning -- 26. Sexual medicine and andrology / Klaus M. Beier -- 27. Male contribution to contraception / Eberhard Nieschlag -- 28. Vasectomy and refertilization / Udo H. Engelmann and Oliver Gralla -- 29. Approaches to hormonal male contraception / Eberhard Nieschlag and Hermann M. Behre -- 30. Pharmacological approaches to male contraception / Trevor G. Cooper and Ching-Hei Yeung -- 31. Ethical aspects of reproductive medicine / Klaus Demmer.
- Biennial review of infertility. Volume 1 v. 1, 2009Springer
- Biennial review of infertility. Volume 2 v. 2, 2011SpringerAutoimmunity and Female Infertility: Fact vs. Fiction -- Minimal Stimulation IVF -- Current Understanding of Anti-Müllerian Hormone -- The Role of Obesity in Reproduction -- Endometrial Receptivity in Natural and Controlled Ovarian-Stimulated Cycles -- Current Understanding of Mullerian-Inhibiting Substance -- Evidence-Based Use of Progesterone During IVF -- Monozygotic Twinning and Perinatal Outcomes -- Multiple Pregnancy Vanishing Twin Syndrome -- The Effect of Cancer Therapies on Sperm: Current Guidelines -- Environmental Insults on Spermatogenesis -- Sperm DNA Damage: Causes and Guidelines for Current Clinical Practice -- The Emerging Role of the Sperm Epigenome and its Potential Role in Development -- ART and Epigenetic Disorders: Should We Be Concerned? -- Novel Approaches of Sperm Selection for ART: The Role of Objective Biochemical Markers of Nuclear and Cytoplasmic Integrity and Sperm Function -- The Role of the Oocyte in Remodeling of Male Chromatin and DNA Repair: Are Events During the Zygotic Cell Cycle of Relevance to ART? -- Proteomic/Metabolomic Analysis of Embryos: Current Status for Use in ART -- Ultrasound-Guided Embryo Transfer -- IMSI as a Valuable Tool for Sperm Selection During ART -- Thoughts on IMSI.
- Biennial review of infertility. Volume 3 v. 3, 2013SpringerPart I: Male Infertility -- 1. Supplements to Enhance Male Fertility / Peter N. Schlegel -- 2. Poor Quality Ejaculate Sperm: Do the Data Support the Use of Testis Sperm? / Robert D. Oates -- 3. The Aging Male and Impact on Offspring / Timothy G. Jenkins, Kenneth I. Aston, and Douglas T. Carrell -- 4. Testosterone Replacement Therapy in Men: Effects on Fertility and Health / Peter T.K. Chan -- Part II: Female Infertility -- 5. A Practical Approach to Recent Advancesin Ovarian Reserve Testing / Benjamin Leader and Valerie L. Baker -- 6. Maternal Age and Oocyte Aneuploidy: Lessons Learned from Trisomy 21 / Stephanie L. Sherman, Emily G. Allen, and Lora J.H. Bean1 -- 7. Fertility Preservation for Cancer Patients / Suneeta Senapati and Clarisa R. Gracia -- 8. Reproductive Surgery and Computer-Assisted Laparoscopy: The New Age of Subspecialty Surgery Is Here / Shane T. Lipskind and Antonio R. Gargiulo -- Part III: Assisted Reproduction Techniques -- 9. Advances in Systems for Embryo Culture / Roberta Maggiulli, Lisa Dovere, Filippo Ubaldi and Laura Rienzi -- 10. Patient-Tailored Approaches to Ovarian Stimulation in ART / Theodora C. van Tilborg, Frank J.M. Broekmans, Helen L. Torrance and Bart C. Fauser -- 11. Cryopreserved Oocyte Banking: Its Prospects and Promise / Kathryn J. Go, Zsolt Peter Nagy, and Ching-Chien Chang -- 12. Reproductive Tourism / Raphael Ron-El -- Part IV: Evolving Controversies in Contemporary Reproductive Medicine -- 13. Intrauterine Insemination: An Ineffective Treatment / Erica B. Johnstone and Jessie Dorais -- 14. IUI Is a Valuable and Cost-Effective Therapy for Most Couples / Lobke M. Moolenaar, Bradley J. Van Voorhis and Fulco van der Veens -- 15. Vitrification of Human Oocytes and Embryos: An Overview / Juergen Liebermann -- 16. Should We Eliminate Fresh Embryo Transfer from ART? / Daniel J. Kaser, Maria Assens, and Catherine Racowsky -- 17. ICSI Is a Revolutionary Treatment of Male Infertility That Should Be Employed Discriminately and Further Studied / Douglas T. Carrell -- 18. The Need for Long-Term Follow-Up of Children Conceived Through ICSI / Rachel Weinerman, Kurt T. Barnhart, and Suleena Kansal Kalra -- 19. Popularity of ICSI / Gianpiero D. Palermo, Queenie V. Neri, Trina Fields and Zev Rosenwaks -- Part V: Clinical Research Design -- Cohort Designs: Critical Considerations for Reproductive Health.
- Cancer and sexual health 2011SpringerFunctional Anatomy of the Male Sex Organs -- Functional Anatomy of the Female Sex Organs -- Physiology of Libido -- Physiology of Orgasm -- Physiology of Female Genital Sexual Arousal -- Physiology of Erection -- Physiology of Ejaculation -- Classifying Female Sexual Dysfunction -- Hypoactive Sexual Desire Disorder -- Disorders of Female Sexual Arousal -- Disorders of Female Orgasm -- Sexual Pain Disorders -- Erectile Dysfunction: Prevalence and Pathophysiology -- Androgen Deficiency -- Peyronie?s Disease -- Disorders of Ejaculation and Male Orgasm -- Priapism -- The Sexual Health Interview: Male -- The Sexual Health Interview: Female -- Communication About Sexuality and Cancer -- Validated Questionnaires in Female Sexual Function Assessment -- Validated Questionnaires in Male Sexual Function Assessment -- Evaluation of the Female with Sexual Dysfunction -- Evaluation of Male Sexual Dysfunction -- The Impact of Cancer on the Partner?s Sexuality -- Gay and Lesbian Patients with Cancer -- The Impact of a Cancer Diagnosis on Sexual Health -- Breast Cancer -- Gynecological Cancers -- Pelvic Surgery for Urological Cancers -- Pelvic Radiation in Men -- Pelvic Radiation in Women -- Impact of Chemotherapy and Hormone Therapy on Female Sexual Health -- Impact of Androgen Deprivation Therapy on Men?s Sexual Health -- Colorectal Cancer -- Stem Cell Transplant --Sexual Health in the Terminally Ill -- Survivorship: An Overview -- Nutriceuticals in Sexual Health -- Medical Treatments for Sexual Problems in Women -- Surgical Treatments for Sexual Problems in Women -- Sex Therapy in Female Sexual Dysfunction -- Erectile Dysfunction: Pharmacological Therapy -- Erectile Dysfunction: Devices -- The Management of Premature Ejaculation -- Testosterone Therapy in the Male Cancer Patient -- Sex Therapy in Male Sexual Dysfunction -- Restoring Intimacy in Relationships Affected by Cancer -- Dating and Disclosure for Cancer Survivors.
- Cell death in mammalian ovary 2011Springer[Publisher-supplied data] The ovary is a suitable organ for studying the processes of cell death. Cell death was first described in the rabbit ovary (Graaffian follicles), the phenomenon being called chromatolysis. To date, it is recognized that various forms of cell death (programmed cell death, apoptosis and autophagy) are essential components of ovarian development and function. Programmed cell death is responsable for the ovarian endowment of primordial follicles around birth; in the prepuberal and adult period, apoptosis is a basic mechanism by which oocytes are eliminated by cancer therapies and environmental toxicants; in the ovarian cycle, follicular atresia and luteal regression involve follicular cell apoptosis. Finally, abnormalities in cell death processes may lead to ovarian disease such as cancer and chemoresistance. In this book, after an introductory description of various forms of cell death and of the ovary development and function in mammals, the processes of cell death in ovarian somatic cells and oocytes are described at cytological, physiological and molecular levels and analyzed in the embryonic, prepuberal and adult ovary. A complex array of molecular pathways triggered by extrinsic and intrinsic signals able tor induce or suppress cell death in the same cell, according to cell type and ovary developmental stage, emerges. Physiological interactions with the axis hypothalamus-hypophysis as well as ovarian internal functional signal are also critically reviewed to explain the abortive development of follicles before the beginning of the ovarian cycle. The book conveys information useful to the updating of biologists and physicians who are interested to the ovary biology and functions. Hopefully it should provide also clues for stimulating novel experiments in the study of cell death in the mammalian ovary still at an early stage.
- Print Material
- Molecular biology for clinicians -- Hormone biosynthesis, metabolism, and mechanism of action -- The ovary-embryology and development -- The uterus -- Neuroendocrinology -- Regulation of the menstrual cycle -- Sperm and egg transport, fertilization, and implantation -- The endocrinology of pregnancy -- Normal and abnormal sexual development -- Normal and abnormal growth and pubertal development -- Amenorrhea -- Chronic anovulation and the polycystic ovary syndrome -- Hirsutism -- Menstrual disorders -- Abnormal uterine bleeding -- The breast -- Menopause and the perimenopausal transition -- Postmenopausal hormone therapy -- Obesity -- Reproduction and the thyroid -- Family planning, sterilization, and abortion -- Oral contraception -- Vaginal and transdermal estrogen-progestin contraception -- Long-acting methods of contraception -- Intrauterine contraception -- Barrier methods of contraception and withdrawal -- Female infertility -- Recurrent early pregnancy loss -- Endometriosis -- Male infertility -- Induction of ovulation -- Assisted reproductive technologies -- Ectopic pregnancy -- Appendix-I: Interpreting epidemiologic reports -- Appendix-II: Selected laboratory values and the international system of units (SI Units).
- Clinical management of male infertility 2015SpringerThis book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book's straightforward approach ensures that it can be easily and rapidly consulted.
- Clinical management of vulvodynia tips and tricks 2011SpringerEpidemiology of Vulvar Pain and its Sexual Comorbidities -- Vulvodynia -- What's Behind the Name? -- Vulvodynia and Dyspareunia -- How Should they be Addressed? -- Postpartum Dyspareunia and Vulvodynia -- What Women with Vulvodynia Complain of: Evaluation of Vulvar Pain -- How Vulvodynia Originates: the Pathophysiology of Vulvar Pain -- How to Make a Comprehensive Diagnosis of Vulvodynia and its Comorbidities -- How to Treat Vulvodynia.
- The Clinical practice handbook for safe abortion care is intended to facilitate the practical application of the clinical recommendations from the second edition of Safe abortion: technical and policy guidance for health systems (World Health Organization [WHO] 2012). While legal, regulatory, policy and service-delivery contexts may vary from country to country, the recommendations and best practices described in both of these documents aim to enable evidence-based decision-making with respect to safe abortion care.
- Clinical uro-andrology 2015SpringerAndrology is a discipline united in a mission to achieve and maintain the sexual health of men, and more broadly couples, over the entire lifespan. In this volume, undisputed leading experts from Europe and beyond come together to cover the field in its entirety, providing a guide that will be of value to urologists and other physicians in their daily clinical practice. It is designed for a wide audience, including both those coming into contact with andrological issues for the first time and more experienced readers requiring updated guidelines and advice on the most controversial and thorny issues. A wide range of topics is covered, including male genital abnormalities, disorders of pubertal development, gender identity disorders, Peyronieℓ́ℓs disease, sexual dysfunction, hypogonadism and infertility, urogenital infections, urogenital cancers, and andrological emergencies. Clinical Andrology will prove an invaluable quick consulting tool, rigorous in its scientific content but at the same time easy to read and rich in images and tables.
- Most general rheumatologists and OB/GYNs have limited experience in caring for rheumatic disease patients during pregnancy, and many do not have ready access to expert colleagues in this area. Contraception and Pregnancy in Patients with Rheumatic Disease fills this gap by presenting the basics of contraception, fertility treatment, and pregnancy in rheumatic disease patients. This comprehensive resource begins by introducing key concepts that clinicians need to know when assessing the pregnant rheumatic disease patient. It goes on to cover specific rheumatic conditions in pregnancy, including systemic lupus erythematosus, antiphospholipid syndrome, systemic sclerosis, inflammatory myositis, and more. The book concludes by explaining additional related reproductive issues such as contraception, neonatal lupus, and long-term outcome of children of rheumatic disease patients. With advances in rheumatology therapies, obstetric monitoring, and reproductive medicine technologies, increasing numbers of women with rheumatic diseases are pursuing pregnancy. Summarizing the current state of knowledge and presenting a general approach for assessment of the rheumatic disease, this book serves as an invaluable reference tool for both rheumatologists and OB/GYNs.
- Contraception for the medically challenging patient 2014SpringerWomen with chronic medical problems are at higher risk for complications during pregnancy and, therefore, they are especially in need of appropriate preconception and contraception care. Furthermore, many women with chronic medical problems do not obtain adequate preconception and contraception care. Despite published guidelines by the Centers for Disease Control and Prevention, there is a substantial gap in medical practice regarding the use of contraception in women with co-existing medical problems. Contraception for the Medically Challenging Patient fills the gap that currently exists in the knowledge of correct contraceptive prescribing practice and shows that inappropriate contraindications can easily become a barrier to effective contraception use among women. Chapters highlight obsolete views about appropriate candidates for contraception and address the complex contraceptive needs of today's medically challenging patients with HIV/AIDS, uterine fibroids, or cardiac, neurologic or thyroid disease. The book gives attention to recommendations on the use of contraception in women with medical problems such as diabetes, obesity, epilepsy, and lupus, among others, and provides comprehensive information regarding the effects that certain drugs may have on contraceptive hormone levels. While national guidelines do exist for contraceptive eligibility, this book discusses in more detail the evidence behind the guideline recommendations and the nuances that clinicians confront in daily practice.
- CT virtual hysterosalpingography 2014SpringerThis book provides a comprehensive review of CT Virtual Hysterosalpingography, a new non-invasive diagnostic technique that allows the evaluation of the entire gynecologic tract in a single study, by combining the benefits of hysterosalpingography (HSG) with multidetector Computed Tomography (CT). The addition of 64-row CT scanners with HSG has significantly improved visualization and assessment of the uterine cavity and fallopian tubes, and allows for the diagnosis of polyps, myomas, uterine anomalies and tubal pathology with a high degree of accuracy. CT Virtual Hysterosalpingography is written and edited by the leaders in the field and covers all aspects of the technique, from its origin and technical principles through to descriptions of the normal anatomy and most common pathologies. This will be an essential text for Gynecologists, Infertility Specialists, Radiologists and Reproductive Endocrinologists who would want to learn about this technique and how it can be implemented in their practice.
- This book addresses the impacts of current and future reproductive technologies on our world food production and provides a significant contribution to the importance of research in the area of reproductive physiology that has never been compiled before. It would provide a unique opportunity to separate the impacts of how reproductive technologies have affected different species and their contributions to food production. Lastly, no publication has been compiled that demonstrates the relationship between developments in reproductive management tools and food production that may be used a reference for scientists in addressing future research areas. During the past 50 years assisted reproductive technologies have been developed and refined to increase the number and quality of offspring from genetically superior farm animal livestock species. Artificial insemination (AI), estrous synchronization and fixed-time AI, semen and embryo cryopreservation, multiple ovulation and embryo transfer (MOET), in vitro fertilization, sex determination of sperm or embryos, and nuclear transfer are technologies that are used to enhance the production efficiency of livestock species.
- An overview of physical growth and maturation / Hills, A.P., Byrne, N.M. -- Role of various cytokines and growth factors in pubertal development / Casazza, K., Hanks, L.J., Alvarez, J.A. -- Body composition differences in normal weight, obese-overweight, and anorexic adolescents : role of adipocytokines / Ondrak, K.S., Hackney, A.C. -- Inflammatory cytokines and metabolic risk factors during growth and maturation : influence of physical activity / Rubin, D.A., Hackney, A.C. -- Visfatin and adiponectin levels in children : relationships with physical activity and metabolic parameters / Mäestu, J., Jürimäe, J., Jürimäe, T. -- Ghrelin and obestatin concentrations during puberty : relationships with adiposity, nutrition, and physical activity / King, N.A., Gibbons, C.H., Martins, C. -- Menstrual irregularities and energy deficiency in physically active women : the role of ghrelin, PYY, and adipocytokines / Scheid, J.L., De Souza, M.J. -- Influence of ghrelin and adipocytokines on bone mineral density in adolescent female athletes with amenorrhea and eumenorrheic athletes / Russell, M., Misra, M. -- Bone turnover markers during pubertal development : relationships with growth factors and adipocytokines / Jürimäe, J., Mäestu, J., Jürimäe, T. -- Exercise training, physical fitness, and the growth hormone-insulin-like growth factor-1 axis and cytokine balance / Eliakim, A., Nemet, D. -- Growth hormone-insulin-like growth factor-1 and inflammatory response to a single exercise bout in children and adolescents / Nemet, D., Eliakim, A. -- Effect of acute and chronic exercise on ghrelin and adipocytokines during pubertal development / Kraemer, R.R., Castracane, V.D.
- Cytopathological techniques for the diagnosis of glandular lesions of the genital tract -- Bethesda System Classification of glandular lesions on cervical cytology -- Cytopathology of the benign glandular lesions of the cervix and glandular cytopathology of the vagina -- Cytopathology of adenocarcinoma in situ of the endocervix and its differential diagnosis -- Cytopathology of the malignant invasive lesions of the endocervix -- Endometrial hyperplasias -- Endometrial adenocarcinoma : current status and future of prevention and early diagnosis -- Cytopathology of ovarian lesions : the intraoperative approach -- Glandular lesions of the vulva -- Glandular lesions of the fallopian tube -- Metastatic glandular lesions -- Ancillary techniques for the diagnosis of glandular lesions of the female genital tract
- Ectopic pregnancy-- a clinical casebook 2015SpringerComprised exclusively of clinical cases covering ectopic pregnancy, this concise, practical casebook will provide clinicians in reproductive medicine and obstetrics/gynecology with the best real-world strategies to properly diagnose and treat the various forms of the condition they may encounter. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome and clinical pearls and pitfalls. Cases included illustrate different management strategies ? from treatment with methotrexate to surgical interventions ? as well as types of ectopic pregnancy, such as ovarian, interstitial, heterotopic and abdominal forms, among others. Pragmatic and reader-friendly, Ectopic Pregnancy: A Clinical Casebook will be an excellent resource for reproductive medicine specialists, obstetricians and gynecologists, and family and emergency medicine physicians alike.
- Endocrine and reproductive physiology. 4th ed. 2013ClinicalKeyIntroduction to the endocrine system -- Endocrine function of the gastrointestinal tract -- Energy metabolism -- Calcium and phosphate homeostasis -- Hypothalamus-pituitary complex -- The thyroid gland -- The adrenal gland -- Life cycle of the male and female reproductive system -- The male reproductive system -- The female reproductive system -- Fertilization, pregnancy, and lactation.
- Epidemiology of human congenital malformations 2014SpringerAuthored by Bengt Kallen, professor emeritus in embryology at Lund University in Sweden. The subject of this book is to describe the occurrence of congenital malformations among children born and what risk factors exist. Population data are presented for a number of malformations, ascertained with the use of data from the Swedish national health registers for the period 1998-2010 corresponding to some 1.3 million births, together with prospectively collected information on a group of exposures of possible interest.
- Epigenetics and human reproduction 2011Springerpt. 1. Medical aspects and questions raised on the molecular basis of epigenome involvement in reproduction -- pt. 2. Fundamental aspects of genome and epigenome reprogramming during gametogenesis -- pt. 3. Re-organization of nuclear compartmetns during gametogenesis -- pt. 4. Fundamental aspects of gene expression regulation during gametogenesis.
- Introduction: the scope of the topic -- Racial and ethnic groups of interest in fertility research -- The impact of sociocultural and economic factors -- Fertility differences among ethnic groups -- Disparities between black and white women in assisted reproductive technology -- Assisted reproductive outcomes in hispanic patients -- Reproductive and assisted reproductive technology (ART) outcomes in East Asian women -- Differences in fertility and assisted reproduction in South Asian women -- Ethnicity and IVF -- Ethnic disparity in oocyte donation outcome -- Frozen embryo transfer outcomes among racial and ethnic groups -- Understanding racial disparity in adverse pregnancy outcome -- Racial diversity and uterine leiomyoma -- The effect of obesity on fertility and ART success among ethnic groups -- Polycystic ovary syndrome across racial and ethnic groups -- Ethnicity and ovariean response: the role of FSH receptor genotype -- Ethnic differences in fertility and assisted reproduction: ethnic disparity in stem cell availability and research -- How can we bridge the gap? Role of insurance mandate -- Toward a better understanding of racial disparities in utilization and outcomes of IVF treatment in the USA.
- Using the new ESHRE/ESGE classification system, this book presents all uterine, cervical and vaginal anomalies in a systematic way. The diagnostic work-up of women with female genital malformations is reviewed in an evidence-based fashion, taking into account the availability of new non-invasive diagnostic methods. The treatment strategies and the therapeutic alternatives to restore health are also critically reviewed. Female Genital Tract Congenital Malformations: Classification, Diagnosis and Management assesses all the latest information concerning the pathogenesis, diagnosis and treatment of female genital malformations. It is a vital manual for all trainees and practitioners within the fields of obstetrics and gynecology, radiologists, researchers in the field of human reproduction, fertility specialists, endoscopists, and ultrasonographers.
- Female puberty a comprehensive guide for clinicians 2014SpringerFemale Puberty: A Comprehensive Guide for Clinicians is a practical reference, covering the full range of issues related to pubertal development. Developed to answer pointed clinical questions and to provide a thorough review of the literature, the book covers both the basics and the complexities of puberty, encompassing psychosocial development to pubertal nuances in highly specialized populations. Comprehensive in scope, this title offers concepts that are concisely conveyed and chapters that complement each other well. Complex subjects such as details of the hypothalamic-pituitary-ovarian axis are covered in a readily understandable manner, and bullet points throughout the text serve as helpful reminders to the reader. An invaluable contribution to the literature, Female Puberty: A Comprehensive Guide for Clinicians will be of great interest to all health providers concerned with female reproductive health - including obstetrician gynecologists, reproductive endocrine specialists, pediatricians, pediatric specialists, family practitioners, and allied health professionals.
- Fertility control 2010SpringerPart 1. Female Reproduction -- New Insights into Ovarian Function / JoAnne S. Richards and Stephanie A. Pangas -- Estrogen Signaling in the Regulation of Female Reproductive Functions / J. K. Findlay, S. H. Liew, E. R. Simpson and K. S. Korach -- Progesterone Receptors and Ovulation / Orla M. Conneely -- Contraception Targets in Mammalian Ovarian Development / Eileen A. McLaughlin and Alexander P. Sobinoff -- Proteomics of Embryonic Implantation / T. Garrido-Gómez, F. Dominguez and C. Simón -- Evaluation of Plasma Membrane Calcium/Calmodulin-Dependent ATPase Isoform 4 as a Potential Target for Fertility Contro / Elizabeth J. Cartwright and Ludwig Neyses -- Part 2. Male Reproduction -- New Insights into Sperm Physiology and Pathology / R. John Aitken, Mark A. Baker, Geoffry N. De Iuliis and Brett Nixon -- The Epididymis as a Target for Male Contraceptive Development / B. T. Hinton and T. G. Cooper -- Sperm-Zona Pellucida Interaction: Molecular Mechanisms and the Potential for Contraceptive Intervention / Matthew D. Dun, Lisa A. Mitchell, R. John Aitken and Brett Nixon -- Mouse Models as Tools in Fertility Research and Male-Based Contraceptive Development / Duangporn Jamsai and Moira K. O'Bryan -- Part 3. New options: From target to product -- Male Hormonal Contraception / E. Nieschlag -- Family Planning: Today and in the Future / Michael J. K. Harper.
- Fertilization 2002ScienceDirectGamete transport / Susan S. Suarez -- Sperm motility activation and chemoattraction / Timothy A. Quill and David L. Garbers -- Capacitation / Bijay S. Jaiswal and Michael Eisenbach -- Function of the egg's extracellular matrix / Richard A. Cardullo and Catherine D. Thaler -- Sperm adhesion to the extracellular / Ming Bi, Michael J. Wassler, and Daniel M. Hardy -- Signal transduction mechanisms regulating sperm acrosomal exocytosis / Gregory S. Kopf -- Regulation of sperm ion currents / Alberto Darszon, Felipe Espinosa, Blanca Galindo, Daniel Sánchez, and Carmen Beltrán -- Function of the sperm acrosome / George L. Gerton -- Gamete fusion in mammals / Paul Primakoff and Diana G. Myles -- Membrane events of egg activation / Karl Swann and Keith T. Jones -- Molecular genetics of fertilization / Patricia Olds-Clarke and Stephen H. Pilder -- Gemete immunobiology / M.G. O'rand and I.A.Lea -- Fertilization biophysics / D.P.L. Green -- Applications of fertility regulation for the management of wild and domestic species / Mark P. Bradley and Peter Bird.
- This volume represents an up-to-date overview on the major areas of gynecological endocrinology, providing the reader with a complete explanation of female endocrine regulation and metabolism and relevant disorders and treatment. It is published within the International Society of Gynecological Endocrinology (ISGE) Series and is based on the 2013 International School of Gynecological and Reproductive Endocrinology Summer Course. The book covers a very wide range of topics from primary amenorrhea to menopause, from the impact of ovarian surgery on fertility to fertility cryopreservation, from metabolic syndrome and polycystic ovary to premature ovarian failure and from the clinical impact of selective progesterone receptor modulators to the use of progesterone in prevention of premature labor. It will be an important tool for obstetricians and gynecologists, endocrinologists and experts in women's health as well as interested GPs.
- Frontiers in gynecological endocrinology. Volume 2, From basic science to clinical application 2015SpringerThis volume offers an up-to-date overview on the major areas of gynecological endocrinology, presenting the latest advances in adolescent gynecological endocrinology, assisted reproduction, menstrual-related disorders, sexuality and transsexualism, polycystic ovary syndrome, myometrial pathology and adenomyosis, obesity and metabolic syndrome, hormonal contraception, premature ovarian failure and menopause. In each chapter the recent advances deriving from basic science and clinical investigations are related to the practical management of the condition under consideration, taking into account the need for individualized therapies. The book is published within the ISGE Book Series, a joint venture between the International Society of Gynecological Endocrinology and Springer and is based on the 2014 International School of Gynecological and Reproductive Endocrinology Winter Course. It will be an important tool for obstetricians and gynecologists, endocrinologists and experts in women?s health as well as interested GPs.
- Futures of reproduction bioethics and biopolitics 2011SpringerIssues in reproductive ethics, such as the capacity of parents to choose children, present challenges to philosophical ideas of freedom, responsibility and harm. This book responds to these challenges by proposing a new framework for thinking about the ethics of reproduction that emphasizes the ways that social norms affect decisions about who is born. The book provides clear and thorough discussions of some of the dominant problems in reproductive ethics - human enhancement and the notion of the normal, reproductive liberty and procreative beneficence, the principle of harm and discrimination against disability - while also proposing new ways of addressing these. The author draws upon the work of Michel Foucault, especially his discussions of biopolitics and norms, and later work on ethics, alongside feminist theorists of embodiment to argue for a new bioethics that is responsive to social norms, human vulnerability and the relational context of freedom and responsibility. This is done through compelling discussions of new technologies and practices, including the debate on liberal eugenics and human enhancement, the deliberate selection of disabilities, PGD and obstetric ultrasound.
- Gamete and embryo-fetal origins of adult diseases 2014SpringerThe book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians.
- Genetic damage in human spermatozoa 2014SpringerThere are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to aging, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. This book provides a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.
- Hormonal and genetic basis of sexual differentiation disorders and hot topics in endocrinology proceedings of the 2nd world conference 2011SpringerPt. 1. Genetic disorders of steroids : speakers -- pt. 2. Prenatal diagnosis of congenital adrenal hyperplasia : speakers -- pt. 3. Treatment of congenital adrenal hyperplasia : speakers -- pt. 4. Receptor defects : speakers -- pt. 5. Psychological aspects of intersex : speakers -- pt. 6. Embryology of sex differentiation : speakers -- pt. 7. Disorders of sex differentiation : speakers -- pt. 8. Hormonal hypertension : speakers -- pt. 9. Skeletal biology : speakers -- pt. 10. Posters.
- Human chorionic gonadotropin (hCG). 1st ed. 2010ScienceDirectPart A: Introduction -- 1. The Expanding World of hCG -- 2. History and Introduction to Human Chorionic Gonadotropin (hCG): One Name for at Least Three Independent Molecules -- 3. Introduction to Pregnancy Implantation, Villous Formation, and Hemochorial Placentation -- Part B: Genetics, Synthesis, Secretion, Structure, and Degradation of hCG -- 4. The Molecular Genetics of hCG -- 5. Structure, Synthesis, Secretion, and Function of hCG -- 6. Comparison of the Structures of hCG and Hyperglycosylated hCG -- 7. Structures of Free a- and ss-Subunits -- 8. Glycobiology of hCG -- 9. Degradation Products of hCG, Hyperglycosylated hCG, and Free ss-Subunit -- 10. Three-Dimensional Structure of hCG -- Part C: Biological Function of hCG -- 11. Paradigm Shift on the Targets of hCG Actions -- 12. The hCG Receptor -- 13. Biological Function of Hyperglycosylated hCG -- 14. Biological Function of the Free ss-Subunit: Expression and Treatment Target in Cancer -- Part D: Clinical Applications -- 15. Use of hCG in Reproductive Dysfunction -- 16. hCG in Assisted Reproduction -- 17. Illicit Use of hCG in Dietary Programs and Use to Promote Anabolism -- Part E: hCG Tests -- 18. Antibodies for Intact hCG, for Total hCG, for Free Subunits, Glycosylation Variants, and for hCG Fragments -- 19. Quantitative hCG Assays -- 20. False Positive hCG Assays -- 21. Specificity of Different hCG Assays -- 22. Point-of-Care Pregnancy Tests -- 23. Over-the-Counter Pregnancy Tests -- 24. hCG Standards -- Part F: Test Applications -- 25. Background hCG -- 26. Pregnancy Testing -- 27. Predicting Spontaneously Aborted (SAB) Pregnancies -- 28. hCG, Hyperglycosylated hCG, and Free ss-Subunit in Predicting Down Syndrome Pregnancies and Preeclampsia -- 29. hCG in Monitoring Gestational Trophoblastic Diseases -- 30. Use of Hyperglycosylated hCG as a Unique Marker of Gestational Trophoblastic Neoplasms -- 31. Pituitary hCG and Familial hCG -- 32. hCG, Free ss-Subunit, and ss-Core Fragment as Markers of Malignancies -- Part G: Basic Methods -- 33. hCG and Hyperglycosylated hCG Purification and Analysis from Serum, Urine, and Culture Fluids -- 34. Dissociation, Desialylation, and Cleavage of hCG -- 35. hCG and Free ss-Subunit Producing Cell Lines -- Part H: Evolution, Summary, and the Future -- 36. Evolution of hCG, Evolution of Humans, and Evolution of Human Pregnancy Disorders and Cancer -- 37. Summary: hCG a Remarkable Molecule -- 38. hCG and the Future.
- In vitro fertilization-- a comprehensive guide 2012SpringerIn Vitro Fertilization: A Comprehensive Guide represents the next frontier in the integrated clinical and laboratory practice of ART. Uniquely balanced, the book provides the necessary understanding of the key laboratory techniques involved in ART and the complex aspects of clinical care. Featuring the contributions of world leaders in the field, the guide begins with the evaluation of the infertile woman and man. It then moves on to discuss treatment protocols and adjunctive treatments. Techniques for oocyte retrieval and insemination, embryo culture and transfer, and micromanipulation procedures are explored in detail. This comprehensive book covers all aspects of IVF and includes special sections on oocyte and embryo donation as well as gestational carriers, making it ideal for practicing clinicians. Advances such as pre-implantation genetic diagnosis and screening, in vitro maturation, and means of fertility preservation, including oocyte and ovarian tissue cryopreservation, are also covered. The book concludes with dedicated chapters on quality assessment and improvement, regulation and legal concerns, and stress and ART. Readers will gain complete in-depth knowledge of the most current therapies and techniques, enabling optimal care and counsel of their infertile patients.
- Kisspeptin signaling in reproductive biology 2013Springer
- Knobil and Neill's Physiology of reproduction. 3rd ed. 2006ScienceDirectv. 1. Gametes, fertilization and embryogenesis -- Female reproductive system -- Male reproductive system -- Pituitary and hypothalamus -- v. 2. Reproductive behavior and its control -- Reproductive processes and their control -- Pregnancy -- Lactation.
- Male infertility problems and solutions 2011SpringerInitial consultation for male infertility -- Interpretation of basic semen analysis and advanced semen testing -- Azoospermia: diagnosis and management -- Ejaculatory dysfunction -- Genetic issues with male infertility -- Endocrinopathies in male infertility -- Female infertility: implications to management of male factor -- Variocele: to fix or not to fix -- Medical management of male infertility -- Surgical reconstructions for obstruction -- Techniques for sperm harvest -- Sperm banking: when, why, and how? -- Assisted reproduction and male factor fertility: which type is right? -- Ethical dilemmas in male infertility.
- Part 1. Male Infertility Diagnosis and Management -- Causes of Male Infertility / Herbert J. Wiser, Jay Sandlow and Tobias S. Köhler -- Laboratory Evaluation for Male Infertility / Ryan Mori and Edmund Sabanegh Jr. -- Imaging Modalities in the Management of Male Infertility / Marcello Cocuzza and Sijo J. Parekattil -- Endocrinopathies / Sam Haywood, Eric L. Laborde and Robert E. Brannigan -- Molecular Mechanisms of Antioxidants in Male Infertility / Kathleen Hwang and Dolores J. Lamb -- Surgical Treatment for Male Infertility / Sandro C. Esteves and Ricardo Miyaoka -- Microsurgery for Male Infertility: The AIIMS Experience / Rajeev Kumar -- Advanced Techniques of Vasoepididymostomy / Wayland Hsiao and Marc Goldstein -- Grafting Techniques for Vasectomy Reversal / Henry M. Rosevear and Moshe Wald -- Mini-Incision Vasectomy Reversal Using the No-Scalpel Vasectomy Instruments and Principles / Darby J. Cassidy, Keith Jarvi, Ethan D. Grober and Kirk C. Lo -- Robotic Microsurgery for Male Infertility and Chronic Orchialgia / Jamin V. Brahmbhatt and Sijo J. Parekattil -- Robot-Assisted Vasectomy Reversal / Peter Frank De Wil, Vincenzo Ficarra, George A. de Boccard and Alexandre Mottrie -- Robotic-Assisted Varicocelectomy / Tung Shu and Run Wang -- Epidemiological Considerations in Male Infertility / Mark A. Faasse and Craig S. Niederberger -- Male Infertility from the Developing Nation Perspective / Kasonde Bowa and John S. Kachimba -- Ethical Dimensions of Urology: Four Case Studies / Marc S. Cohen and Ray E. Moseley -- Management of Fertility in Male Cancer Patients / Daniel H. Williams IV -- Genetic Aspects of Male Infertility / Orhan Bukulmez -- Novel Approaches in the Management of Klinefelter Syndrome / Fnu Deepinder -- ART and Its Impact on Male Infertility Management / Alice Rhoton-Vlasak and Kenneth C. Drury -- Part 2. Spermatozoa Metabolism -- Fuel/Energy Sources of Spermatozoa / M. M. Misro and T. Ramya -- Oxidative Stress / Fanuel Lampiao, C. J. Opperman, Ashok Agarwal and Stefan S. du Plessis -- Loss of Intracellular Antioxidant Enzyme Activity During Sperm Cryopreservation: Effects on Sperm Function After Thawing / Juan G. Alvarez -- Part 3. Common Male Infertility Disorders -- Varicocele / Sandro C. Esteves -- Infection in Infertility / Ralf Henkel -- Ejaculatory Dysfunction and Vasodynamics / Aleksey P. Ignatov and Paul J. Turek -- Environmental Factors / Claudio Telöken, Samuel Juncal and Túlio M. Graziottin -- Exogenous Medication or Substance-Induced Factors / Kubilay Inci and Levent Mert Gunay -- Sperm DNA Damage and Antioxidant Use: Roles in Male Fertility / Ashok Agarwal and Aspinder Singh -- Common Male Infertility Disorders: Aging / Fabio Pasqualotto, Edson Borges Jr. and Eleonora Pasqualotto -- Apoptosis and Male Infertility / S. Vaithinathan, Shereen Cynthia D'Cruz and P. P. Mathur -- Impact of Spinal Cord Injury / Viacheslav Iremashvili, Nancy L. Brackett and Charles M. Lynne -- Obesity and Male Fertility / Stephanie Cabler, Ashok Agarwal and Stefan S. du Plessis -- Part 4. Nutrition and Antioxidants Role for Male Reproductive Health -- Nutritional Pathways to Protect Male Reproductive Health / Tung-Chin Hsieh and Paul Shin -- Natural Antioxidants / Giancarlo Balercia, Antonio Mancini and Gian Paolo Littarru -- Synthetic Antioxidants / Edmund Y. Ko, John C. Kefer, Ashok Agarwal and Edmund Sabanegh -- Antioxidant Therapy for the Enhancement of Male Reproductive Health: A Critical Review of the Literature / Kelton Tremellen -- In Vitro Studies of Antioxidants for Male Reproductive Health / Armand Zini and Maria San Gabriel -- Part 5. Assisted Reproductive Technologies in Male Fertility -- Micro-testicular Sperm Extraction / Doron Sol Stember and Peter Schlegel -- Sperm Processing and Selection / Sonja Grunewald and Uwe Paasch -- Antioxidants in Sperm Cryopreservation / Tamer Said and Ashok Agarwal -- Antioxidants in ICSI / Nicolas Garrido, Sandra García-Herrero, Laura Romany, José Remohí and Antonio Pellicer, et al. -- Antioxidants in IMSI / Monica Antinori -- Role of Sperm-Hyaluronic Acid Binding in the Evaluation and Treatment of Subfertile Men with ROS-Affected Semen: Assessment of Sperm with Oxidative Damage and HA-Mediated ICSI Sperm Selection / Ciler Celik-Ozenci and Gabor Huszar -- Extended Embryo Culture Supplementation / Alex C. Varghese, Eulalia Pozo-Guisado, Ignacio S. Alvarez and Francisco Javier Martin-Romero -- Part 6. Special Topics -- Best Practice Guidelines for the Use of Antioxidants / Francesco Lanzafame, Sandro La Vignera and Aldo E. Calogero -- Harmful Effects of Antioxidant Therapy / Adam F. Stewart and Edward D. Kim.
- Management of penile cancer 2014SpringerManagement of Penile Cancer provides a comprehensive and state-of-the-art overview of the major issues specific to the field of penile cancer. The sections of the book are structured to review the overall scope of issues of penile cancer, including diagnosis and staging, surgical approaches, and the treatment of advanced disease. As multidisciplinary care is an integral part of the treatment of penile cancer, this book is unique in the inclusion of collaborating authors from a variety of integrated disciplines, including urology, radiation oncology, medical oncology, and reconstructive surgery. Written by recognized experts in their field, Management of Penile Cancer is a unique and valuable resource in the field of penile cancer, both for those currently in training and for those already in clinical or research practice.
- Men's health 2013SpringerMen's Health is a concise, didactic compendium that covers three important aspects of male sexual health:- Testosterone Deficiency Syndrome; Premature Ejaculation and Sexually Transmitted Infections (STIs).The chapters that deal with Testosterone Deficiency Syndrome cover the epidemiology of the condition in the local context, the science behind the condition, its clinical presentation and treatment choices.The section on Premature Ejaculation advises the health practitioner on how to investigate this condition and describes the various treatment options available to the patient.The chapters on Sexually Transmitted Infections cover special aspects of the diagnosis, prevention and treatment of STIs occurring in Men which are not normally highlighted in the usual texts on STI management.Written by experts in the field, Men's Health is a valuable and timely resource for urologists, andrologists, endocrinologists as well as other health professionals practicing in these areas.
- In the last decade, much of the clinical interest in the field of infertility has focused on advancing reproductive techniques and has often under-appreciated the role that male sexuality plays in reproductive problems. Male sexual function is an integral part of reproduction, and the treatment of sexual dysfunction is an important component for any couple seeking fertility. In some cases, treatment of sexual dysfunction may obviate the need for more invasive cures through advanced reproductive techniques. Thanks to recent clinical and scientific advances in male sexual medicine, the management of men's sexual dysfunction is often more effective and less invasive than how it was historically described. Men's Sexual Health and Fertility is the only resource that focuses on the interplay and interconnections between male sexual dysfunction and male factor infertility, gathering insightful data from a panel of experts in male sexual medicine for clinicians who treat couples with fertility issues due to male sexual dysfunction. Chapters discuss advances in the field of men's sexual medicine, including the latest treatment for erectile dysfunction, the most up-to-date understanding of the physiology and pathophysiology of ejaculation, and the growing body of evidence that low testosterone and male infertility are intimately related. As such, this book provides important information in order to be able to better understand the link between sexual dysfunction and infertility and, most importantly, to better treat male sexual dysfunction in the infertile couple.
- Male Infertility Microsurgical Training / Philip S. Li, Ranjith Ramasamy and Marc Goldstein -- Microsurgery Training: What Should a Resident Know? Should All Microsurgeons be Fellowship Trained? / Ethan Grober and Peter N. Kolettis -- Microsurgical Subinguinal Varix Ligation: Techniques and Technical Pearls / Joshua A. Bodie and Jay I. Sandlow -- Vasovasostomy Techniques for Microsurgery Specialists / Kalen Rimar, Landon Trost and Robert E. Brannigan -- Epididymovasostomy: Tips and Tricks of the Trade / James F. Smith and Ajay K. Nangia -- Sperm Retrieval Techniques in Obstructive Azoospermia: MESA, PESA, and TESA / Anand Shridharani and Jay I. Sandlow -- Microsurgical Testicular Sperm Extraction: Technical Considerations / Peter N. Schlegel -- Noninfertility Scrotal Microsurgery / Akanksha Mehta and Marc Goldstein -- Testis-Sparing Surgery for Testicular Masses / Oleksandr Stakhovskyi and Michael A. S. Jewett -- Robotic Microsurgery for Male Infertility / Sijo J. Parekattil, Ahmet Gudeloglu and Jamin V. Brahmbhatt -- The Role of Microsurgical Reconstruction in the Era of ICSI / Karen Baker and Edmund Sabanegh Jr -- Tubal Microsurgery / Jeffrey M. Goldberg and Tommaso Falcone -- Microsurgical Penile Revascularization, Replantation, and Reconstruction / Jeffrey Lee Rosenblum and Arthur L. Burnett.
- "Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse provides a detailed insight into "when, why, what and how" of various minimally invasive surgical procedures for surgical management of SUI, OAB & POP. The volume provides detailed diagrammatic and pictorial step-by-step descriptions of the techniques and management of complications related to these procedures. This book also presents an up to date, one-stop reference for anything pertaining to MIT of these pelvic disorders. Written by experts in the field, Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse is a comprehensive resource designed for both the urologist and urogynecologist treating patients with urinary disorders and pelvic organ prolapsed, as well as for residents in training."--Publisher's website.
- Molecular mechanisms in spermatogenesis 2008SpringerSpermatogenesis and cycle of the seminiferous epithelium / Rex A. Hess and Luiz Renato de Franca -- Testicular development and spermatogenesis : harvesting the postgenomics bounty / Antoine D. Rolland, Bernard Jogou and Charles Pineau -- Estrogens and spermatogenesis / Chandrima Shaha -- Selenium, a key element in spermatogenesis and male fertility / Carla Boitani and Rossella Puglisi -- Extracellular matrix and its role in spermatogenesis / Michelle K.Y. Siu and C. Yan Cheng -- Inflammatory networks in the control of spermatogenesis : chronic inflammation in an immunologically privileged tissue? / Moira K. O'Bryan and Mark P. Hedger -- Transcription regulation in spermatogenesis / Wing-Yee Lui and C. Yan Cheng -- Proteases and their cognate inhibitors of the serine and metalloprotease -- Subclasses, in testicular physiology / Brigitte Le Magueresse-Battistoni -- Antioxidant systems and oxidative stress in the testes / R. John Aitken and Shaun D. Roman -- Nitric oxide and cyclic nucleotides : their roles in junction dynamics and spermatogenesis / Nikki P.Y. Lee and C. Yan Cheng -- The sertoli cell cytoskeleton / A. Wayne Vogl, Kuljeet S. Vaid and Julian A. Guttman -- Blood-testis barrier, junctional and transport proteins and spermatogenesis / Brian P. Setchell -- Cross-talk between tight and anchoring junctions : lesson from the testis / Helen H.N. Yan ... [et al.] -- The role of the leydig cell in spermatogenic function / Renshan Ge, Guorong Chen and Matthew P. Hardy.
- Nuclear transfer protocols cell reprogramming and transgenesis 2006Springer ProtocolsCloning of exotic/endangered species: (desert bighorn sheep) / James "Buck" Williams ... [et al.] -- Handmade somatic cell cloning in cattle / Gábor Vatja, Ian M. Lewis, and R. Tayfur Tecirlioglu -- Genetic modification of sheep by nuclear transfer with gene-targeted somatic cells / A. John Clark, Sarah Burl, and Chris Denning -- Transgenesis using nuclear transfer in goats / Anthoula Lazaris ... [et al.] -- Nuclear reprogramming : an overview / Takashi Tada -- Expression of imprinted genes in cloned mice / Takashi Kohda, Fumitoshi Ishino, and Atsuo Ogura -- Nuclear remodeling assay in xenopus egg extract / Koichi Gonda and Nobuaki Kikyo -- In vitro reprogramming of nuclei and cells / Anne-Mari Håkelien ... [et al.] -- Techniques for nuclear transfer to mouse embryonic stem cells / Danielè Pralong and Paul J. Verma -- Gene expression and methylation patterns in cloned embryos / Christine Wrenzycki ... [et al.] -- Are there any normal clones? / Ian Wilmut -- Future and applications of cloning / Alan O. Trounson. Origin and progress of nuclear transfer in nonmammalian animals / Marie A. Di Berardino -- In vitro maturation and embryo production in cattle / Marc-André Sirard and Karine Coenen -- Activation of oocytes after nuclear transfer / Zoltán Macháty -- Culture medium preferences of pre-implantation cloned mouse embryos / Björn Heindryckx, Josiane Van der Elst, and Marc Dhont -- Maintenance of pregnancy in pigs with limited viable embryos / Tim King and Paul A. De Sousa -- Health and neonatal care of bovine clones / Jacqui T. Forsyth and David N. Wells -- Optimization of procedures for cloning by somatic cell nuclear transfer in mice / Young Gie Chung, Shaorong Gao, and Keith E. Latham -- Production of cloned calves using roscovitine-treated adult somatic cells as donors / Kazuchika Miyoshi, Sezen Arat, and Steven L. Stice -- A double nuclear transfer technique for cloning pigs / Irina A. Polejaeva, Shawn Walker, and Keith Campbell -- Nuclear transfer in nonhuman primates / Shoukhrat M. Mitalipov and Don P. Wolf --
- Introduction to Obesity and Fertility -- Obesity and the HPO axis -- Childhood and Adolescent Obesity: Implications for Reproductive Health and Function -- Nutrition in Human Fertility -- Preconceptional Obesity and Fetal Outcomes?Transdisciplinary Evidence for Obesity?s Effects on Fertility -- Fertility Treatment Outcomes in Obese Women -- Early Pregnancy in Obese Women -- Obesity in Pregnancy -- Contraceptive Counseling in Obese Women -- Obesity and Ovarian Aging (Diminished Ovarian Reserve and Menopause) -- Obesity, Reproductive Outcomes, and Access to Infertility Treatments: A Clinical and Ethical Debate -- Surgical Interventions and Reproductive Function in Obese Women -- Conclusions: Establishing an Ethically and Medically Sound Framework for Integrating BMI Limits Into Infertility Care for Obese Women.
- Office andrology 2005SpringerEssentials of sperm biology / Sharon T. Mortimer -- Endocrinology of male infertility / R. Dale McClure -- Sperm preparation for insemination / Grace M. Centola -- Specialized sperm testing: pros and cons / Kirk C. Lo ... [et al.] -- Genetic testing for male infertility / Robert D. Oates -- Optimizing success in a donor insemination program / Phillip E. Patton -- Ethical and legal considerations of donor insemination in the United States / Karen E. Adams -- Laboratory accreditation / William Byrd -- Office evaluation of male infertility / Darius A. Paduch and Eugene F. Fuchs -- Varicocele and infertility / Ulrike Zenke and Paul Turek -- Strategic therapies for ejaculatory disorders and erectile dysfunction in the infertile man / Mustafa F. Usta and Wayne J. G. Hellstrom -- Vasectomy reversal / Eugene F. Fuchs and Darius A. Paduch -- Infection and male infertility / Emmett F. Branigan -- Obstructive and nonobstructive azoospermia / Kinloch Nelson and Peter Schlegel -- Testis biopsy and the infertile male / Sherman J. Silber -- Intracytoplasmic sperm injection: the process, the outcomes, and the controversies / David E. Battaglia -- Treatment of human immunodeficiency virus-discordant couples / Joseph E. Peña and Mark V. Sauer -- Sperm and egg retrieval for posthumous reproduction: practical, ethical, and legal considerations / Lisa V. Brock and Anna C. Mastroianni -- Gender selection: separating fact from fiction / David S. Karabinus and Keith L. Blauer.
- Office-based gynecologic surgical procedures 2015SpringerRecent trends in medicine have pushed many gynecologic procedures to the outpatient setting, whether in-office, in small medical ambulatory surgery centers, or in procedure rooms. Office-Based Gynecologic Surgical Procedures covers both basic and advanced procedures, from biopsy and saline ultrasound to cystoscopy. It answers the "How?", "What?", and "When?" of setting up, preparing for, and confidently performing office procedures. While appropriate training and certification in these procedures such as cystoscopy and hysteroscopy is needed, this book is an excellent resource for advice and tips on how to safely transition from the technique used in the operating room. It also provides the necessary algorithms and in-depth instructions pertinent to performing these types of procedures effectively in the office setting. A chapter on patient safety in the office is also included. Office-Based Gynecologic Surgical Procedures is ideal for established OBGYNs in practice who want to expand their range of procedures offered in-office, fellows in Women's Health, advanced nurse practitioners, recent OBGYN residency graduates, and family medicine physicians eager to familiarize themselves with women's health procedures.
- Oncofertility communication sharing information and building relationships across disciplines 2014SpringerOncofertility integrates the two previously distinct fields of cancer treatment and fertility research and aims to explore and expand the reproductive future of cancer survivors. In order to achieve the goal of fertility preservation, the Oncofertility community must focus on communication and the way data is provided and received. Concomitant with the rapidly changing technology of Oncofertility, there have been radical shifts and advances in the way health educators and clinicians can produce and share information. As success rates of reproductive techniques such as egg freezing and banking continue to rise, providing increasing opportunities for young cancer patients to preserve their fertility prior to the onset of cancer treatments, communication among professionals in oncology, reproductive medicine, and psychosocial work, among others, becomes crucial, and clinical demand for Oncofertility information is expected to rise considerably. Oncofertility Communication describes and addresses the myriad channels through which the multiple audiences involved in Oncofertility can be served with appropriate and accurate information about cancer-related fertility issues. The text answers frequently asked questions and provides invaluable insights to scientific and health care professionals about communication among the diverse Oncofertility audiences. It incorporates timely discussions about traditional and emerging electronic communication tools and discusses the impact of health care policy changes on the Oncofertility field.
- Part I. The Science and Technology of Oncofertility -- Reproductive health after cancer -- Designing follicle-environment interactions with biomaterials -- Gamete preservation -- To transplant or not to transplant: that is the question -- Clinical cases in oncofertility -- Cancer genetics: risks and mechanisms of cancer in women with inherited susceptibility to epithelial ovarian cancer -- Protecting and extending fertility for females of wild and endangered mammals -- -- Part II. Historical and Legal Perspectives -- Placing the history of oncofertility -- Medical hope, legal pitfalls: potential legal issues in the emerging field of oncofertility -- Domestic and international surrogacy laws: implications for cancer survivors -- -- Part III. Clinical and Theoretical Ethics -- Adoption after cancer: adoption agency attitudes and perspectives on the potential to parent post-cancer -- Ovarian tissue cryopreservation and bioethical discourse -- Lessons of oncofertility for assisted reproduction -- Morally justifying oncofertility research -- Ethical dilemmas in oncofertility: an exploration of three clinical scenarios -- Participation in investigational fertility preservation research: a feminist research ethics approach -- Reproductive "choice" and egg freezing -- Impact of infertility: why ART should be a higher priority for women in the global south -- Oncofertility and informed consent: addressing beliefs, values, and future decision making -- -- Part IV. Religious Perspectives -- Bioethics and oncofertility: arguments and insights from religious traditions -- Sacred bodies: considering resistance to oncofertility in Muslim communities -- Unlikely motherhood in the Qur'an: oncofertility as devotion -- Technology and wholeness: oncofertility and Catholic tradition -- Jewish perspectives on oncofertility: the complexities of tradition -- -- Part V. Ramifications for Education and Economics -- Oncofertility Saturday academy: a paradigm to expand the educational opportunities and ambitions of high school girls -- Myoncofertility.org: a web-based patient education resource supporting decision making under severe emotional and cognitive overload -- Anticipating ovarian tissue cryopreservation in the health-care marketplace: a willingness to pay assessment -- Perspectives on oncofertility from demography and economics -- For the sake of consistency and fairness: why insurance companies should cover fertility preservation treatment for iatrogenic infertility -- -- Part VI. Repercussions of Oncofertility for Patients and Their Families -- Health provider perspectives on fertility preservation for cancer patients -- Counseling and consenting women with cancer on their oncofertility options: a clinical perspective -- Fertility-related treatment choices of cancer patients: cancer-related infertility and family dynamics -- Whose future is it?: ethical family decision making about daughters' treatment in the oncofertility context -- -- Part VII. Healthcare Provider Stories and Final Thoughts -- Choosing life when facing death: understanding fertility preservation decision-making for cancer patients -- Discussing fertility preservation with breast cancer patients -- Warning: Google can be hazardous to your health: fertility preservation is an important part of cancer care -- Role of a patient navigator in fertility preservation -- Judaism and reproductive technology -- Reading between the lines of cancer and fertility: a provider's story -- Rewarding experience for a pediatric urologist -- Final thoughts.
- Part I. Introduction -- The emergence of a new discipline: oncofertility / Teresa K. Woodruff -- Part II. Fertility risk and treatment options -- Fertility management for women with cancer / Sanjay K. Agarwal and R. Jeffrey Chang -- Fertility preservation in adult male cancer patients / Robert E. Brannigan -- Managing fertility in childhood cancer patients / Kimberley J. Dilley -- Fertility risk in pediatric and adolescent cancers / Clarisa R. Gracia and Jill P. Ginsberg -- Part III. Oncofertility techniques and research -- Bioengieneering and the ovarian follicle / Min Xu, Teresa K. Woodruff, and Lonnie D. Shea -- The science of cryobiology / Steven F. Muller and John K. Critser -- Ovarian tissue cryopreservation and transplantation: banking reproductive potential for the future / David Lee -- Progress, history and promise of ovarian cryopreservation and transplantation for pediatric cancer patients / Yasmin Gosiengfiao -- Part IV. Health care decision-making -- Oncofertility and the social sciences / Karrie Ann Snyder -- Shared decision making: fertility and pediatric cancers / Marla L. Clayman, Kathleen M. Galvin, and Paul Arnston -- Part V. Ethical and psychosocial impact of cancer-related infertility -- Today's research, tomorrows cures: the ethical implications of oncofertility / Leilah E. Backhus and Laurie Zoloth -- The psychosocial context of cancer-related infertility / Matthew J. Loscalzo and Karen L. Clark -- Childhood cancer: fertility and psychosocial implications / Karen E. Kinahan, Aarati Didwania, and Carrie L. Nieman -- Fertility preservation and adolescent cancer patients: lessons from adult survivors of childhood cancer and their parents / Carrie L. Nieman ... [et al.] -- Part VI. Training in a new medical discipline and medical guidelines -- Oncofertility: a new medical discipline and the emerging scholar / Laxmi A. Kondapalli -- Oncofertility Consortium consensus statement: guidelines for ovarian tissue cryopreservation / Leilah E. Backhus ... [et al.] -- Part VII. Patient stories and oncofertility -- Personal accounts of cancer and infertility / provided by Fertile Hope.
- Oocyte biology in fertility preservation 2013SpringerFertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation strategies should be based on the sound scientific knowledge and principles. One of the main objectives of fertility preservation in females is prevention of oocyte depletion. The mechanisms of oocyte loss and survival in the ovary are complex, which include genetic control both in germ cells and in somatic cells, DNA damage and repair mechanism, apoptosis and autophagy, and other poorly understood molecular mechanisms.To develop clinically effective and safe strategies for fertility preservation, it is essential to know and understand the fundamentals of oocyte and ovarian biology at the molecular level. Thus, the purpose of this edition is to review the current progress in research related to molecular and genetic control of oocyte development that can be applied to fertility preservation. The main topics that are discussed in this publication include molecular signaling mechanisms of oocyte activation and loss, genomic integrity of oocytes, and epigenetics.
- Oogenesis 2013SpringerThe oocyte is the largest and most mysterious cell in the body of mammalian organisms. Through its growth and maturation, it reaches extreme levels of specialization, while maintaining at the same time a condition of totipotency. Its unique ability, in co-operation with the spermatozoon, to give rise to a fully developed organism formed from hundreds of different tissues and myriads of individual cells has inspired intellectuals of all ages.Oogenesis finds impetus and purpose in casting scientific perspective towards this unique cell for the benefit of scientists and assisted reproductive technology (ART) specialists. The authors of the chapters are distinguished authorities in their respective areas of competence. From the opening of the book the reader is lead on a fantastic voyage from the formation of the primordial oocyte to the development of the early embryo, passing through crucial processes of oogenesis, such as co-ordination of oocyte and follicle growth, gene expression and organelle reorganization during growth and maturation, epigenetic mechanisms, regulation of meiosis, totipotency, cell polarity, oogenesis in vitro and maternal regulation of early development.
- Physiology and pharmacology of erectile dysfunction / Rafael Carrion ... [et al.] -- Epidemiology of erectile dysfunction / Jonathan D. Schiff and John P. Mulhall -- Pharmacology of phosphodiesterase inhibitors / Erwin Bischoff -- Sildenafil citrate, the classical PDE5 inhibitor: a five-year review of its efficacy and safety in the arena of erectile dysfunction / Harin Padma-Nathan -- Tadalafil: clinical trials experience / Culley C. Carson, III -- Vardenafil: clinical trials experience / Ajay Nehra -- Erectile dysfunction assessment and management in primary care practice / Louis Kuritzky and Martin Miner -- When to refer the patient with erectile dysfunction to a specialist / Ira D. Sharlip -- Erectile dysfunction: assessing risk and managing the cardiac patient / Thorsten Reffelmann and Robert A. Kloner -- Is diabetic erectile dysfunction more difficult to treat? / Pierre Theuma and Vivian A. Fonseca -- Depression and antidepressant-associated erectile dysfunction / Raymond C. Rosen -- Intracavernous, transurethral, and topical therapies for erectile dysfunction in the era of oral pharmacotherapy: salvaging first-line therapy, failures with combination therapies / Hans-Martin A. Fritsche, Mustafa F. Usta, and Wayne J.G. Hellstrom -- Androgen deficiency of the aging male: enhancing erectile response to oral pharmacotherapy / Alvaro Morales and Jeremy P.W. Heaton -- Central activation of erection and clinical experience / Jeremy P.W. Heaton, Alvaro Morales, and Michael A. Adams -- Sustaining the cure: oral pharmacotherapy failures salvage with vacuum devices and penile implants / Ronald W. Lewis -- Prevention and treatment of erectile dysfunction utilizing lifestyle changes and dietary supplements: what works and what is worthless? / Mark A. Moyad -- Pharmacological strategies in the management of rapid ejaculation / Chris G. McMahon -- Sexual dysfunction after radical prostatectomy and the use of PDE-5 inhibitors / Andrew McCullough -- Female sexual dysfunction: is there a magic pill? / Ridwan Shabsigh ... [et al.].
- Ovulation induction and controlled ovarian stimulation a practical guide. Second edition. [2nd ed.] 2014SpringerThe second edition of this highly successful book updates the reader on progress and developments in the field of ovulation induction and controlled ovarian stimulation. Furthermore, it provides the busy clinician with a reliable overview of the principles involved and the management needed. As with the previous edition, the emphasis throughout this book is on logical evidence and evidence-based solutions, supplemented with Professor Roy Homburgs extensive clinical experience gleaned from more than forty years working in the field. A number of highly useful algorithms and explanatory tables reinforce this approach, ensuring that the reader is presented with easy-to-grasp, well-presented information that maximizes clarity and understanding. Ovulation Induction and Controlled Ovarian Stimulation: A Practical Guide offers a concise, no-nonsense, practical guide to ovulation induction and controlled ovarian stimulation and will be an essential resource for general gynaecologists, fertility specialists and trainees, health workers and students.
- Covering a comprehensive range of common, rare, benign and malignant lesions, Pathology of the Female Reproductive Tract, 3rd Edition, authored by an international panel of subspecialty experts, brings you the latest scientific and diagnostic information for diseases of the female reproductive tract. From basic concepts of pathophysiology and diagnostic criteria to clinical correlation, this updated medical reference book delivers an integrated and practical approach to diagnosis and management of women with reproductive tract disorders. Quickly and easily access key information with user-friendly bullet points, diagnostic flowcharts, decision-making algorithms, summary tables, and take-home messages, as well as a "Road Map" at the beginning of each chapter for effortless navigation.Avoid diagnostic errors with the help of practical, expert advice on common pitfalls in differential diagnosis. Browse the complete contents from any location with online access at Expert Consult.
- Pathology of the placenta. 3rd ed. 2007ClinicalKeyAppendix 1: Placental weight -- Appendix 2: Medicolegal aspects of placental pathology. Pathology of the placenta: an introduction and overview -- The development and structure of the placenta -- Physiology of the placenta -- Abnormalities of placentation and of placental development -- Macroscopoic abnormalities of the placenta -- Histological abnormalities of the placenta -- The placenta in pregnancies of abnormal duration -- The placenta in maternal disorders -- The placenta in abnormalities and disorders of the fetus -- The placenta in miscarriage -- Infections and inflammatory lesions of the placenta -- The placenta in multiple pregnancy -- Immunopatholgoy of the placenta -- Non-trophoblastic tumours of the placenta -- Gestational trophoblastic disease -- Pathology of the umbilical cord -- Pathology of the membranes -- Correlation of ultrasonic and pathological findings.
- Pluripotency in domestic animal cells 2013SpringerThis addition to the Springer Brief in Stem Cells series focuses on aspects related to the specific mechanisms that ensure and control pluripotency and cell commitment in domestic animal species. This topic is generating rapidly-increasing interest due to the great potential for domestic animal species to be used as intermediate biomedical models, between the mouse and the human. The Brief addresses why we need large animal models for regenerative medicine. It also describes early embryo development with a careful and specific analysis of the regulatory mechanisms driving cleavage, polarization and genome activation in domestic species. How pluripotency is compartmentalized in domestic species as well as the different aspects that make the derivation of stem cells in domestic species very difficult are also addressed.
- Polycystic ovary syndrome : definitions, phenotypes and diagnostic approach / S. Livadas, E. Diamanti-Kandarakis -- Pathophysiology of polycystic ovary syndrome : the role of hyperandrogenism / S. Catteau-Jonard, D. Dewailly -- Genetics of polycystic ovary syndrome / T.M. Barber, S. Franks -- Obesity, adipokines and metabolic syndrome in polycystic ovary syndrome / E. Carmina -- Dyslipidemia and oxidative stress in PCOs / D. Macut, J. Bjekić-Macut, A. Savić-Radojević -- Cardiovascular risk and subclinical cardiovascular disease in polycystic ovary syndrome / K. Bajuk Studen, M. Jensterle Sever, M. Pfeifer -- Insulin sensitizers in polycystic ovary syndrome / R. Pasquali, A. Gambineri -- Hirsutism : from diagnosis to use of antiandrogens / K. Unluhizarci, Z. Karaca, F. Kelestimur -- Combined oral contraceptives in polycystic ovary syndrome : indications and cautions / G. Bozdag, B.O. Yildiz -- Infertility treatment in polycystic ovary syndrome : lifestyle interventions, medications and surgery / D. Panidis ... [et. al.] -- Endocrinopathies and other disorders inducing a polycystic ovary syndome phenotype / K.I. Alexandraki, G.A. Kaltsas -- Non-classic adrenal hyperplasia due to the deficiency of 21-hydroxylase and its relation to polycystic ovarian syndrome / D. Pignatelli.
- Presenting an overview of the current understanding of the pathophysiology of PCOS and a paradigm for the clinical evaluation and management of the disorder, Polycystic Ovary Syndrome is written in an easy to digest, concise format that, with bulleted key points introducing each chapter, is suitable for the trainee and the busy clinician. The breadth and depth of coverage of today's queries and controversies will be of particular interest to the specialist and researcher. An international group of leading experts addresses the varied etiologies of PCOS, comprehensively covering the contemporary treatment approaches and long-term implications of PCOS, a common yet poorly understood disorder. Chapters on treatment will be of particular relevance to the clinician and the trainee as they cover conventional therapies, lifestyle, and diet, as well as address emerging strategies such as the use of statins and surgery in PCOS management. Spanning the breadth of clinical presentations and morbidities related to the diagnosis of PCOS, Polycystic Ovary Syndrome is an exceptional resource for primary care providers, gynecologists, reproductive endocrinologists, and others involved in the care of these patients, and provides the essential tools to aid clinicians in initiating a timely diagnostic workup and appropriate interventions to address both the immediate and long-term sequelae related to PCOS.
- Sperm proteases and extracellular ubiquitin-proteasome system involved in fertilization of ascidians and sea urchins -- ISGylation: a conserved pathway in mammalian pregnancy -- Src-family tyrosine kinases in oogenesis, oocyte maturation and fertilization: an evolutionary perspective -- Posttranslationally modified tubulins and other cytoskeletal proteins: their role in gametogenesis, oocyte maturation, fertilization and pre-implantation embryo development -- Deubiquitinating enzymes in oocyte maturation, fertilization and preimplantation embryo development -- Posttranslational modifications of zona pellucida proteins -- Role of aberrant protein modification, assembly, and localization in cloned embryo phenotypes -- Role of posttranslational protein modifications in epididymal sperm maturation and extracellular quality control -- Ubiquitin-proteasome system in spermatogenesis -- Role of posttranslational modifications in C. elegans and Ascaris spermatogenesis and sperm function.
- Part 1. Setting Up and Running an IVF Laboratory / Building the Laboratory / Dean E. Morbeck and Marlena Duke -- Air Quality Management / Johan Guns, Ronny Janssens and Martine Vercammen -- Organizational Aspects of the Laboratory in a Tertiary Care ART Center / Nancy L. Bossert and Christopher De Jonge -- Quality Control Management / William R. Boone and H. Lee Higdon -- Daily, Weekly, and Regular Preparations for the IVF Laboratory / Michael A. Britt and Klaus E. Wiemer -- Risk and Safety in the IVF Clinic / Peter Sjoblom and Julius Hreinsson -- Journey of Human Gametes In Vitro: 1978-2010 / Zeev Shoham. Part 2. IVF Laboratory Equipment and Culture Systems -- Essential Instruments and Disposable Supplies for an IVF Laboratory / Leslie Weikert, Christa Fralick and Klaus E. Wiemer -- Co2 and Low-O2 Incubators / Marius Meintjes -- IVF Workstations / Nicolas Prados and Alex C. Varghese -- Culture Media in IVF: Decisions for the Laboratory / Jason E. Swain and Thomas B. Pool. Part 3. In Vitro Fertilization -- Oocyte Denuding / Roberta Maggiulli, Filippo Ubaldi and Laura Rienzi -- Assessment of Oocyte Quality / Basak Balaban, Turgay Barut and Bulent Urman -- Polarization Microscopy / Markus Montag, Maria Köster and Hans van der Ven -- Cumulus Cell Gene Expression in Assessment of Oocyte Quality / Dagan Wells. Part 4. Embryo Culture Methods -- Short Culture: Day 1/Day 2/Day 3 Embryo Culture / Patrick Quinn -- Extended Culture in IVF / David K. Gardner and Michelle Lane -- In Vitro Maturation of Human Oocytes / Baris Ata, Jack Huang and Ri-Cheng Chian -- In Vivo Embryo Culture Device / Claude Ranoux -- Microfluidics for Gamete Manipulation and Embryo Culture / Gary D. Smith, Charles Bormann and Shuichi Takayama. Part 5. Sperm Processing and Selection -- Sperm Assessment: Traditional Approaches and Their Indicative Value / Margot Flint, Fanuel Lampiao, Ashok Agarwal and Stefan S. du Plessis -- Sperm Assessment: Novel Approaches and Their Indicative Value / De Yi Liu, Harold Bourne, Claire Garrett, Gary N. Clarke and Shlomi Barak, et al. -- Sperm Processing for IVF / Ralf Henkel -- PESA/TESA/TESE Sperm Processing / Sandro C. Esteves and Sidney Verza -- Processing Sperm Samples in HIV-Positive Patients / Thamara Viloria, Marcos Meseguer, Antonio Pellicer, José Remohí and Nicolás Garrido -- Intracytoplasmic Morphologically Selected Sperm Injection / P. Vanderzwalmen, Magnus Bach, Batsuren Baramsai, A. Neyer and Delf Schwerda, et al. -- Sperm Testing and ICSI Selection by Hyaluronic Acid Binding: The Hyaluronic Acid-Coated Glass Slide and Petri Dish in the Andrology and IVF Laboratories / Gabor Huszar -- Electrophoretic Sperm Separation / Steven Fleming and John Aitken -- Magnetic-Activated Cell Sorting of Human Spermatozoa / Enver Kerem Dirican -- Polscope-Based Sperm Selection / Luca Gianaroli, Cristina Magli, Andor Crippa, Giorgio Cavallini and Eleonora Borghi, et al.. Part 6. Insemination Procedures -- Intrauterine Insemination / Gautam N. Allahbadia and Rubina Merchant -- Conventional IVF Insemination / Liesl Nel-Themaat, Thomas Elliott, Ching-Chien Chang, Graham Wright and Zsolt Peter Nagy -- Intracytoplasmic Sperm Injection / Gianpiero D. Palermo, Queenie V. Neri, Devin Monahan, Takumi Takeuchi and Peter N. Schlegel, et al. -- Mechanism of Human Oocyte Activation During ICSI and Methodology for Overcoming Low or Failed Fertilization / Dmitri Dozortsev and Mohammad Hossein Nasr-Esfahani. Part 7. Micromanipulators and Micromanipulation -- Hydraulic Manipulators for ICSI / Hubert Joris -- Research Instruments Micromanipulators / Steven Fleming and Catherine Pretty -- Eppendorf Micromanipulator: Setup and Operation of Electronic Micromanipulators / Ehab Abu-Marar and Safa Al-Hasani -- The Leica Microsystems' IMSI System / Christiane Wittemer, Bruno Laborde, Frederic Ribay and Stephane Viville -- Automated Robotic Intracytoplasmic Sperm Injection / Zhe Lu, Xinyu Liu, Xuping Zhang, Clement Leung and Navid Esfandiari, et al. -- Oocyte Treatment and Preparation for Microinjection / Thomas Ebner -- Livestock Production via Micromanipulation / Akira Onishi and Anthony C. F. Perry. Part 8. Embryo Evaluation, Grading, and Assisted Hatching -- Pronuclear Scoring in Human In Vitro Fertilization / Lynette Scott -- Cumulative Morphological Assessment of Embryo Quality / Barry Behr and Aparna Hegde -- Metabolomics: The ViaMetrics-E Procedure for Assessing Embryo Viability / D. Sakkas, L. Botros, M. Henson, K. Judge and P. Roos -- Oxygen Consumption as an Indicator of Oocyte and Embryo Viability / Ana S. Lopes -- Gene Expression Changes During Human Early Embryo Development: New Applications for Embryo Selection / Samir Hamamah, Said Assou, Imène Boumela and Hervé Dechaud -- Amino Acid Turnover as a Biomarker of Embryo Viability / Christine Leary, Danielle G. Smith, Henry J. Leese and Roger G. Sturmey -- Real-Time Embryo Monitoring Device for Embryo Selection / Gábor Vajta and Thorir Hardarson -- Assisted Hatching in IVF / Itziar Belil and Anna Veiga. Part 9. Biopsy Procedures on Oocytes and Embryos -- Polar Body Biopsy / Markus Montag, Maria Köster, K. van der Ven and Hans van der Ven -- Cleavage-Stage Embryo Biopsy / Alan R. Thornhill -- Embryo Biopsy for PGD: Current Perspective / Steven J. McArthur, Don Leigh, Maria Traversa, James Marshall and Robert P. S. Jansen -- Microarrays and CGH for PGD of Chromosome Abnormalities and Gene Defects / Gary Harton and Santiago Munné. Part 10. Cryopreservation -- Sperm Cryopreservation / Fabio Firmbach Pasqualotto, Eleonora Bedin Pasqualotto, Edson Borges and Ashok Agarwal -- Slow Freezing of Oocytes / Giovanni Coticchio and Lucia De Santis -- Vitrification: Research in Animal Models / Gábor Vajta -- Oocyte Vitrification / Ana Cobo -- Slow Freezing of Embryos / Liesl Nel-Themaat, Ching-Chien Chang, Thomas Elliott, Patricia Bernal and Graham Wright, et al. -- Vitrification of Embryos / Juergen Liebermann, Joe Conaghan, Zsolt Peter Nagy and Michael Tucker -- Directional Freezing of Reproductive Cells, Tissues, and Organs / Amir Arav -- Ovarian Tissue Cryopreservation / Jennifer L. Kulp, J. Ryan Martin and Pasquale Patrizio. Part 11. Embryo Transfer -- Assessment of Uterine Receptivity / Hakan Cakmak and Hugh S. Taylor -- Single Embryo Transfer / Thorir Hardarson and Matts Wikland -- Ultrasound-Guided Embryo Transfer (Abdominal/Vaginal): An Evidence-Based Evaluation / Ahmed M. Abou-Setta -- Cumulus-Aided Embryo Transfer / Firuza R. Parikh, Nandkishor J. Naik, Dattatray J. Naik and Dhanajaya Kulkarni. Part 12. Management and Regulation in the ART Laboratory -- Data Management in the ART Laboratory: Requirements and Solutions / Timothy Brown, Bruce R. Gilbert and Bruce R. Gilbert -- Regulation, Licensing, and Accreditation of the ART Laboratory / Doris Baker -- Legislation in the United Kingdom / Rachel Cutting -- Regulation, Licensing, and Accreditation of the ART Laboratory in Europe / Julius Hreinsson and Peter Sjoblom -- Regulation, Licensing, and Accreditation of ART Laboratories in India / B. N. Chakravarty and Rita Modi -- Troubleshooting in the Clinical Embryology Laboratory: The Art of Problem-Solving in ART / Kathryn J. Go, Jay C. Patel and Rick Dietz. Part 13. Special Topics -- The Role of Mitochondria in the Establishment of Developmental Competence in Early Human Development / Jonathan Van Blerkom -- Nuclear and Cytoplasmic Transfer: Human Applications and Concerns / Josef Fulka and Helena Fulka -- Cytoskeletal Architecture of Human Oocytes with Focus on Centrosomes and Their Significant Role in Fertilization / Heide Schatten, Vanesa Y. Rawe and Qing-Yuan Sun -- Molecular Mining of Follicular Fluid for Reliable Biomarkers of Human Oocyte and Embryo Developmental Competence / Jonathan Van Blerkom.
- This unique book offers a comprehensive yet practical user-friendly guide to preimplantation genetic diagnosis (PGD). It provides understanding of and insight into the complete procedure, its recent clinical and laboratory developments and its future prospects, whilst offering an easy point of reference for patient enquiries. Concluding with perspectives on the ethical and social issues often encountered by healthcare professionals counselling patients with regards to PGD. Each chapter within Preimplantation Genetic Diagnosis in Clinical Practice is written by established authorities in their fields. An essential resource for PGD specialists and non-specialists, and for all practitioners working within the disciplines of fertility, reproductive medicine and medical genetics.
- Principles of gender-specific medicine. 2nd ed. 2010ScienceDirect2010 ClinicalKeyChapter 1. The Effects of Gender in Neonatal Medicine / Tove S. Rosen, David Bateman -- Chapter 2. Sexual Development, Growth, and Puberty in Children / Gaya S. Aranoff, Jennifer J. Bell -- Chapter 3. Gender Differences in Pediatric Pulmonary Disease / Beverley J. Sheares -- Chapter 4. Gender-Specific Aspects of Pediatric Hematology and Oncology / James H. Garvin Jr. -- Chapter 5. Gender Differences in Neurological Conditions of Children / David M. Kaufman -- Chapter 6. Gender and Sports: Past, Present, and Future / Jordan D. Metzl -- Chapter 7. Gender Differences in the Functional Organization of the Brain / Ruben C. Gur, Tamara Bockow, Raquel E. Gur -- Chapter 8. Sexual Differentiation of Brain Structure and Function / Margaret M. McCarthy -- Chapter 9. The Sexed and Gendered Brain / William Byne -- Chapter 10. Age and Gender-Specific Patterns of Neurologic Illness / Joan Amatniek, Karin Sorra, Lauren Frey, W. Allen Hauser -- Chapter 11. Gender Differences in Stroke / Rebecca F. Gottesman, Argye E. Hillis -- Chapter 12. Gender Differences in Disorders that Present to Psychiatry / Mary V. Seeman -- Chapter 13. Hormone Replacement Therapy and Cognitive Function / Mary Sano, Diane Jacobs, Katya Gaynor -- Chapter 14. Gender and the Heart: Sex-Specific Differences in the Normal Myocardial Anatomy and Physiology / Marianne J. Legato, Jaswinder K. Leghe -- Chapter 15. Gender-Specific Aspects of Selected Coronary Heart Disease Risk Factors: A Summary of the Epidemiologic Evidence / Shari S. Bassuk, JoAnn E. Manson -- Chapter 16. Dyslipidemia Management in Women and Men: Exploring Potential Gender Differences / Kavita Sharma, Christian D. Nagy, Roger S. Blumenthal -- Chapter 17. Gender Differences in the Role of Stress and Emotion in Cardiovascular Function and Disease / David E. Anderson, Margaret A. Chesney -- Chapter 18. The Role of Sex and Gender in Cardiothoracic Surgery / Sandhya K. Balaram, Justin D. Blasberg -- Chapter 19. Gender Differences in Asthma / Robert H. Lim, Lester Kobzik -- Chapter 20. Gender Issues in Venous Thromboembolism / Susan Murin, Kathryn Bilello, Lisa Moores, Aaron Holley -- Chapter 21. Sleep in Women: Gender Differences in Health and Disease / Shirin Shafazand -- Chapter 22. Are Women More Susceptible to Chronic Obstructive Pulmonary Disease? / Kenneth R. Chapman -- Chapter 23. The Gender-Specific Aspects of Lung Cancer / Rebecca L. Toonkel, Charles A. Powell -- Chapter 24. Gender-Specific Considerations in Pulmonary Hypertension / Deborah Shure -- Chapter 25. Sex and Gender Differences in Pulmonary Manifestations of Autoimmune Disease / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 26. Benign Metastasizing Leiomyoma and Lymphangioleiomyomatosis: Lung Diseases of Women / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 27. Gender Differences in Susceptibility, Outcomes, and Pathophysiology of Sepsis / Kristy A. Bauman, MeiLan K. Han -- Chapter 28. Inflammatory Bowel Disease in Women / Melissa Munsell, Marc Sonenshine, Mary L. Harris -- Chapter 29. Disorders of Defecation in Women / Susan L. Gearhart -- Chapter 30. Idiopathic Gastroparesis: Gender Aspects / Henry P. Parkman -- Chapter 31. Liver Disease in Women / Karen Krok, Ayman Koteish -- Chapter 32. Gender Differences in Irritable Bowel Syndrome / Octavia Pickett-Blakely, Linda A. Lee, Gerald Mullin -- Chapter 33. Contraception / Karen Feisullin, Carolyn Westhoff -- Chapter 34. Infertility: The Male / Howard H. Kim, Peter N. Schlegel, Marc Goldstein -- Chapter 35. Infertility and In Vitro Fertilization / Elizabeth Barbieri, Sonya Kashyap, Pak H. Chung -- Chapter 36. Female Sexual Health / Barbara D. Bartlik, Julie A. Kolzet, Nazia Ahmad, Tahmina Parveen, Sarah Alvi -- Chapter 37. Male Sexual Dysfunction / Serkan Deveci, John P. Mulhall -- Chapter 38. Pelvic Pain: Urogenital Female Disorders / Andrew T. Goldstein, Lara J. Burrows -- Chapter 39. Lower Urogenital Tract Dysfunction in Men and Women / Doreen E. Chung, Alexis E. Te, Renuka Tyagi -- Chapter 40. Aging and the Lower Urogenital System / Catherine E. DuBeau -- Chapter 41. Menopause / Gloria Bachmann, Nora J. Doty -- Chapter 42. The Differences between Male and Female Breast Cancer / Coral Omene, Amy Tiersten -- Chapter 43. Difference in Germ Cell Tumors of the Reproductive Tract in Men and Women / Nicole LaNatra, Amy Tiersten -- Chapter 44. Gender Differences in Hereditary Cancer Syndromes: Risks, Management, and Testing for Inherited Predisposition to Cancer / Wendy K. Chung -- Chapter 45. Gender Differences in Emerging Infectious Diseases / Sharon Lewin -- Chapter 46. Sexually Transmitted Infections in Men and Women / Anne M. Rompalo, Khalil G. Ghanem -- Chapter 47. Infections in Pregnancy / Emilia Mia Sordillo, Bruce Polsky -- Chapter 48. Adult Immunization in Women and Men / Sally L. Hodder, Debra Chew, Shobha Swaminathan -- Chapter 49. Gender Differences in Autoimmune Diseases: Immune Mechanisms and Clinical Applications / Nabih I. Abdou, Virginia Rider -- Chapter 50. Hormones and Cytokines: Gender-Specific Effects / Maurizio Cutolo -- Chapter 51. Prolactin and Autoimmunity / Sara E. Walker -- Chapter 52. Sex Hormones and Immune Function / Robert G. Lahita -- Chapter 53. Pregnancy and Autoimmune Rheumatic Disease / Carl A. Laskin, Christine A. Clark, Karen A. Spitzer -- Chapter 54. Oral Contraceptives and Autoimmune Diseases / Taraneh Mehrani, Michelle Petri -- Chapter 55. Gender-Specific Issues in Organ Transplantation / Hilary Sanfey Chapter 56. Endogenous Sex Hormones and Risk of Type 2 Diabetes Mellitus in Men and Women / Sherita Hill Golden -- Chapter 57. Thyroid Disorders and Pregnancy / Matthew Kim -- Chapter 58. Sexual Function and Dysfunction in Men and Women / Karen Elizabeth Boyle, Arthur L. Burnett -- Chapter 59. Osteoporosis in Men and Women / Kendall F. Moseley, Suzanne M. Jan de Beur -- Chapter 60. Testosterone Replacement Therapy in Men and Women / Diala El-Maouche, Adrian Dobs.
- Prostate cancer prevention 2014SpringerProstate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals, and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed, and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5-reductase inhibitors, DFMO, and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease, and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
- Proteomics of spermatogenesis 2005Springer
- Print MaterialIntroduction: Psychoanalytic impact of assisted reproductive technology / Mali Mann -- Psychoanalytic understanding of repeated in-vitro fertilization trials, failures, and repetition compulsion / Mali Mann -- Family complexes and oedipal circles: mothers, fathers, babies, donors, and surrogates / Diane Ehrensaft -- Psychoanalytic treatment of anxiety related to motherhood and the use of assisted reproductive technology / Terese Schulman -- Egg donors and sperm donors: parental identity formation / Mali Mann and Andrea Mann -- Infertility, trauma, and assisted reproductive technology: psychoanalytic perspectives / Manisha Near-Akhtar -- Assisted reproduction as explored in The Kids Are All Right / Katherine MacVicar.
- Quality management in ART clinics a practical guide 2013SpringerIn the last decades, major advances have been made in assisted reproductive technologies (ART) and the public demand for these procedures has increased globally. All ART clinics, from those just starting out to the well established, must employ the latest equipment and implement the best practices, while ensuring that their resources are effectively engaged to optimize patient outcomes. This is a tenet of the fiduciary role of physicians and it is increasingly recognized as a quantifiable goal regulated by formal certifications and accreditations. Quality management protocols such as those proposed by the International Organization for Standardization (ISO) are being rapidly adopted as standards of measure. Quality Management in ART Clinics: A Practical Guide provides easily adoptable ways to implement and improve formalized quality management systems. Essential to any clinic to achieve best practices and maintenance of formal regulatory certifications, this book brings together the know-how of experienced opinion leaders operating in key areas worldwide. The book offers an overview of primary regulations in the ART field, with attention to quality management demands, and links specific requirements to practical steps for implementation. Filled with process and procedure examples, flow diagrams and administrative form templates, this book is the first of its kind, gathering the necessary elements for optimizing practice, management, and quality assurance.
- Front Matter -- Colour Plates -- Factors of High-Risk Pregnancy. Overview of High-Risk Pregnancy / John T Queenan, Catherine Y Spong, Charles J Lockwood -- Maternal Nutrition / Edward R Newton -- Alcohol and Substance Abuse / William F Rayburn -- Environmental Agents and Reproductive Risk / Laura Goetzl -- Genetics. Genetic Screening for Mendelian Disorders / Deborah A Driscoll -- Screening for Congenital Heart Disease / Lynn L Simpson -- First- and Second-Trimester Screening for Fetal Aneuploidy and Neural Tube Defects / Julia Unterscheider, Fergal D Malone -- Monitoring: Biochemical and Biophysical. Sonographic Dating and Standard Fetal Biometry / Eliza Berkley, Alfred Abuhamad -- Fetal Lung Maturity / Alessandro Ghidini, Sarah H Poggi -- Antepartum Fetal Monitoring / Brian L Shaffer, Julian T Parer -- Interpreting Intrapartum Fetal Heart Tracings / Michael Nageotte -- Maternal Disease. Sickle Cell Anemia / Scott Roberts -- Anemia / Alessandro Ghidini -- Thrombocytopenia / Robert M Silver -- Inherited and Acquired Thrombophilias / Michael J Paidas -- Thromboembolic Disorders / Christian M Pettker, Charles J Lockwood -- Cardiac Disease / Stephanie R Martin, Alexandria J Hill, Michael R Foley -- Renal Disease / David C Jones -- Pregnancy in Transplant Patients / James R Scott -- Gestational Diabetes Mellitus / Deborah L Conway -- Diabetes Mellitus / George Saade -- Hypothyroidism and Hyperthyroidism / Brian Casey -- Asthma / Michael Schatz -- Epilepsy / Autumn M Klein, Page B Pennell -- Chronic Hypertension / Heather A Bankowski, Dinesh M Shah -- Systemic Lupus Erythematosus / Christina S Han, Edmund F Funai -- Perinatal Infections / Jeanne S Sheffield -- Malaria / Richard M K Adanu -- Group B Streptococcal Infection / Ronald S Gibbs -- Hepatitis / Patrick Duff -- HIV Infection / Howard L Minkoff -- Pregnancy in Women with Physical Disabilities / Caroline C Signore -- Obstetric Complications. Recurrent Spontaneous Abortion / Charles J Lockwood -- Cervical Insufficiency / John Owen -- Gestational Hypertension, Preeclampsia, and Eclampsia / Labib M Ghulmiyyah, Baha M Sibai -- Postpartum Hemorrhage / Michael A Belfort -- Emergency Care / Garrett K Lam, Michael R Foley -- Rh and Other Blood Group Alloimmunizations / Kenneth J Moise -- Multiple Gestations / Karin E Fuchs, Mary E D'Alton -- Polyhydramnios and Oligohydramnios / Ron Beloosesky, Michael G Ross -- Prevention of Preterm Birth / Paul J Meis -- Pathogenesis and Prediction of Preterm Delivery / Catalin S Buhimschi, Charles J Lockwood -- Preterm Premature Rupture of Membranes / Brian M Mercer -- Management of Preterm Labor / Vincenzo Berghella -- Placenta Previa and Related Placental Disorders / Yinka Oyelese -- Complications of Labor and Delivery. Prolonged Pregnancy / Teresa Marino, Errol R Norwitz -- Induction of Labor / Nicole M Petrossi, Deborah A Wing -- Cesarean Delivery / Michael W Varner -- Vaginal Birth after Cesarean Delivery / Mark B Landon -- Breech Delivery / Edward R Yeomans, Larry C Gilstrap -- Operative Vaginal Delivery / Edward R Yeomans -- Obstetric Analgesia and Anesthesia / Gilbert J Grant -- Patient Safety / Christian M Pettker -- Neonatal Encephalopathy and Cerebral Palsy / Maged M Costantine, Mary E D'Alton, Gary D V Hankins -- Procedures. Genetic Amniocentesis and Chorionic Villus Sampling / Ronald J Wapner -- Fetal Surgery / Robert H Ball, Hanmin Lee -- Index.
- Reducing risk in fertility treatment 2015Springer1. The Challenges of Multiple Pregnancies -- 2. Prognosis of Risks for Offspring of Fertility Treatment -- 3. Ovarian Hyperstimulation Syndrome -- 4. Thromboembolism Associated with Fertility Treatment -- 5. Emotional and Psychosocial Risk Associated with Fertility Treatment -- 6. Regulatory and Legal Risks for Patients.
- Reproductive and developmental toxicology 2011ScienceDirectReproductive toxicology is a complex subject dealing with three components-parent, placenta, and fetus-and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife.
- Reproductive endocrinology and infertility integrating modern clinical and laboratory practice 2010SpringerCharacteristics of a successful R.E.I. clinic and laboratory -- Assisted reproductive technology practice management -- Collaboration within the reproductive endocrinology and infertility practice: integration of laboratory and clinic operations -- Informed consent in advanced reproductive technology -- Reproductive laboratory regulations, certifications and reporting systems -- Successfully integrating the FDA regulations into your practice -- Psychosocial consequences of infertility and treatment -- A live baby or your money back: the marketing of in vitro fertilization procedures -- Ovulation: a molecular view -- Clinical evaluation of female factor infertility -- Polycystic ovary syndrome -- The current status for Metformin use in reproductive medicine -- Clinical aspects of endometriosis -- Common endocrinopathies in reproductive endocrinology -- Acquired uterine factors and infertility -- Mullerian (paramesonephric) anomalies and associated Wolffian (mesonephric) duct malformations -- Recurrent miscarriage -- Laparoscopy in the diagnosis and treatment of female infertility -- Turner syndrome -- Errors in chromosome segregation during oogenesis and early embryogenesis -- An overview of sperm production -- Meiotic recombination and errors during spermatogenesis -- Clinical evaluation and treatment of male factor infertility -- Semen analysis: essentials for the clinician -- Sperm capacitation, the acrosome reaction, and fertilization -- Advanced tests of sperm function -- Genetic testing of male infertility Varicocele and male infertility -- Sperm retrieval techniques -- The clinical utility of the evaluation of sperm chromatin -- Artificial insemination: intrauterine insemination -- Sperm preparation for artificial insemination -- Sperm banking, donation, and transport in the age of assisted reproduction: federal and state regulation -- Reproductive treatment of HIV-1 discordant couples -- Ovulation induction -- Transvaginal sonography in reproductive endocrinology and infertility -- Establishing the IVF laboratory: a systems view -- Preparation and selection of sperm for IVF and ICSI -- The genetic and epigenetic contributions of sperm to early embryogenesis -- Micromanipulation of human oocytes and embryos: applications of intracytoplasmic sperm injection and assisted hatching in infertility treatment -- Embryo culture techniques -- In-vitro maturation of human oocytes -- Integrating preimplantation genetic diagnosis into the ART laboratory -- Evaluation and selection of preimplantation embryos for transfer -- Embryo transfer in IVF: evidence-based clinical practice -- Cryopreservation of human oocytes and embryos -- Preserving fertility -- Ovarian hyperstimulation syndrome -- Pregnancy outcomes in infertile couples -- The impact of complementary medicine on in-vitro fertilization -- Designing a clinical research infrastructure -- Integrating research into a clinical practice -- Research regulations: the role of the Institutional Review Board -- Technology transfer and its role in the practice of reproductive endocrinology and infertility -- The environment and reproduction: endocrine disruption, reproductive impairment, and epigenetics.
- Principles of cancer treatment: impact on reproduction -- Fertility preservation options for females -- Options for fertility preservation in men and boys with cancer -- Contraception and cancer treatment in young persons -- Sexual health during cancer treatment -- Unique reproductive concerns of young women with breast cancer -- Pregnancy and cancer -- Preimplantation genetic diagnosis for hereditary cancers -- Non-traditional family building planning -- Parenting with cancer I: developmental perspective, communication, and coping -- Parenting with cancer II: parenting at different stages of illness -- Pediatric oncology and reproductive health -- Institutional approaches to implementing fertility preservation for cancer patients -- Patient provider communication and reproductive health -- Fertility preservation in cancer patients: ethical considerations -- Legal issue and of assisted reproductive technologies.
- Reproductive health and the environment 2007SpringerIntroduction -- Environmental Impact on Reproductive Health, Recent Trends and Developments / P. Nicolopoulou-Stamati and N.J. Lelos. Section 1: The Link Between Reproductive Health and Environment. -- Epidemiological Studies on the Relationship between Semen Quality and Environmental Chemicals: Historic and Contemporary Compounds / R. Hauser and J.D. Meeker -- Environment and Fertility / P. Saldiva. Section 2: Reproductive Health Effects. -- Male Reproductive Status and its Relationship with Man-Made, Hormone-Disrupting Substances: Studies In Flanders, Belgium / W. Dhooge, F. Eertmans, A. Mahmoud, and F. Comhaire -- Potential Impact of the Environment on the Male Reproductive Function: The Example Of Cryptorchidism / E. Huyghe, R. Mieusset and P.F. Thonneau -- Advanced Glycation End Products in Polycystic Ovarian Syndrome / E. Diamanti-Kandarakis, C. Piperi, and P. Nicolopoulou-Stamati -- Oocytes and Ovarian Follicles as Targets of Endocrine Disrupters: Consequences for Reproductive Health / F. Gandolfi, T.A.L. Brevini, and F. Cillo. Section 3: Pollutants And Exposure. -- Non-Pesticide Endocrine Disrupters and Reproductive Health / S. Corsolini -- Medical Drugs Impairing Fertility / N. Pandiyan -- Impact of Air Pollution on Reproductive Health in Northern Bohemia / J. Rubes, S.G. Selevan, R.J. Sram, D.P. Evenson, and S.D. Perreault. Section 4: Policy Instruments And Issues. -- Pesticides as Endocrine Disrupters: Identification of Hazards for Female Reproductive Function / M. Rescia and A. Mantovani -- Assessment of Fertility and Other Health Impacts for Selected Pollutants in Flanders: Opportunities and Limitations / J. De Wit, A. Verspecht and L. Hens -- Problems in Assessing Low Dose Effects of Endocrine Disrupters / A. Gies -- Getting the Message Across - WWFs and ISDEs Perspectives on Communication Strategies to Reduce Exposures to Hazardous Chemicals / G. Lyons and P. Illig -- Environmental Ethics and Fertility in Early Cultures and The Industrial Age / A. Katsivelaki and C.E. Sekeris. Section 5: Regional Aspects. -- Reproductive Health Problems in the Greater Athens Area / D.A. Adamopoulos and E. Koukkou -- Environment and Reproductive Health in Bulgaria / S. Stoyanov and E. Terlemesian.
- Reproductive surgery in assisted conception 2015Springer
- During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of fetal breathing movements, cyclic electroencephalographic activity, and analysis of electronic monitoring of fetal heart rate variability and its significance. Included in this book are reminisces of several dozen individuals who played a vital role in these developments. Overall, this survey considers a number of aspects of the development of the science of fetal and neonatal physiology, and its role in the greatly improved care of pregnant women and their newborn infants.
- Sexual function in the prostate cancer patient 2009SpringerSexual dysfunction presents a major challenge to physicians who take on the task of treating men with prostate cancer. While curing the disease and saving a life is paramount, improving technologies and therapies offer skilled surgeons and clinical oncologists the opportunity to eradicate the disease without compromising sexual function. In Sexual Function of the Prostate Cancer Patient, John Mulhall and a panel of internationally recognized experts on prostate cancer and sexual function assess in detail the current state of prostate cancer treatment. The authors offer a broad overview of the pathophysiology and treatment of erectile dysfunction in men with prostate cancer, reviewing the latest findings regarding erection-sparing radiation therapy and sexual function outcomes after laparascopic and robotic prostatectomy. Additional chapters discuss intra-operative maneuvers to minimize post-operative erectile dysfunction and pharmacologic penile preservation and rehabilitation. Timely and authoritative, Sexual Function in the Prostate Cancer Patient is a highly readable guide to preserving post-prostate cancer sexual function that no urologist or radiation and medical oncologist should be without.
- Sperm chromatin biological and clinical applications in male infertility and assisted reproduction 2011SpringerSperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage.
- No evidence for killer sperm or other selective interactions between human spermatozoa in ejaculates of different males in vitro (1999) / Harry D.M. Moore, M. Martin & Tim R. Burkhead -- Psychological adaptation to human sperm competition (2002) / Todd K. Shackelford ... [et al.] -- Semen displacement as a sperm competition strategy in humans (2004) / Gordon G. Gallup & Rebecca L. Burch -- Human female orgasm and male fluctuating asymmetry (1995) / Randy Thornhill, Steve W. Gangestad & Randall Comer. Sperm competition in humans / Nicholas Pound, Todd K. Shackelford, Aaron T. Goetz -- Why are there so many tiny sperm? Sperm competition and the maintenance of two sexes (1982) / Geoffrey A. Parker -- Sperm competition, male prudence, and sperm-limited females (2002) / Nina Wedell, Matthew J.G. Gage & Geoffrey A. Parker -- Human sperm competition (1984) / Robert L. Smith -- "Kamikaze" sperm in mammals? (1988) / R. Robin Baker & Mark A. Bellis -- Deformed sperm are probably not adaptive (1989) / Alexander H. Harcourt -- Elaboration of the kamikaze sperm hypothesis: a reply to Harcourt (1989) / R. Robin Baker & Mark A. Bellis -- Number of sperm in human ejaculates varies in accordance with sperm competition theory (1989) / R. Robin Baker & Mark A. Bellis -- Do females promote sperm competition? Data for humans (1990) / Mark A. Bellis & R. Robin Baker -- Human sperm competition: ejaculate adjustment by males and the function of masturbation (1993) / R. Robin Baker & Mark A. Bellis -- Human sperm competition: ejaculate manipulation by females and a function for the female orgasm (1993) / R. Robin Baker & Mark A. Bellis --
- State of inequality-- reproductive, maternal, newborn and child health interactive visualization of health data 2015WHO"Achieving equity in health requires a commitment to monitoring health inequalities which, in turn, necessitates strong, equity-oriented health information systems. High-quality data and robust monitoring systems ensure that efforts can be targeted appropriately and that progress can be tracked. Countries must strengthen health information systems to generate better data and evidence to measure progress. Integral to the health inequality monitoring process is the task of reporting data in a meaningful way. This State of inequality report exemplifies effective reporting practices, featuring the topic of reproductive, maternal, newborn and child health. The report addresses the challenge of how to best communicate a large and complex body of data in a manner that is comprehensible, flexible and appealing to a wide readership. Foreword viii Feature stories provide an in-depth look at the state of inequality for selected indicators and highlight key observations in reproductive health interventions, maternal health interventions, care-seeking for sick children, childhood immunization, child malnutrition and child mortality. Perhaps most notable, however, is the innovative use of electronic visualization technology. Story-point dashboards, for instance, guide the reader through a succession of visuals where readers can use interactive tools to further explore, sort and filter the data. Similarly, interactive maps and tables engage readers in customizing how data are viewed. The report reveals that significant inequalities exist in low- and middle-income countries in the area of reproductive, maternal, newborn and child health. The good health of women, infants and children is essential for sustainable development, and there is still much work to be done. Discussions will increasingly call into question how efforts to improve reproductive, maternal, newborn and child health can achieve early and accelerated progress among those who are falling behind."--Pages viii-ix
- Studies on men's health and fertility 2012Springer
- This volume provides a brief resume of the history of testosterone research, from the early pioneers through to the most recent advances in the field. We discover how steroid hormones were first identified and how testosterone was shown to be essential for male development. Moving forward we explore how and where testosterone is produced, and how the body controls testosterone production. We then investigate the impact testosterone has on different body systems both during their development and function, and how perturbation of testosterone action is associated with disease. We complete our story with an exploration of the emerging roles of testosterone in clinical therapy, and the future potential for manipulation of the testosterone signaling system for human health benefit.
- Textbook of clinical embryology 2013Cambridge"The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook - inspired by the postgraduate degree program at the University of Oxford - guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology"--Provided by publisher.
- Third-party reproduction a comprehensive guide 2014SpringerThe first IVF conceived birth in 1978 resulted in a significant growth of third party reproductive options which continue to raise ethical, legal, and psychological questions. Third party reproduction procedures can involve as many as five people: sperm donor, egg donor, gestational carrier, and intended parents. Third-Party Reproduction: A Comprehensive Guide utilizes experts in the field to address the medical, psychological, ethical and legal aspects of sperm donation, egg donation, embryo donation, and the use of gestational carriers. In addition, there are chapters on the medical and ethical aspects of posthumous reproduction, religious aspects of third party reproduction, and how to avoid pitfalls of third party reproduction. Aimed at physicians, trainees, psychologists, nurses, and social workers whose practices may include patients considering third party reproduction, the intent of this book is to provide a comprehensive and practical overview of the many aspects of third party reproduction to help all those involved to better understand them. Patients considering third party reproduction may also find value in this book.
- Treatment of infertility with Chinese medicine. Second edition [2nd ed.] 2013ScienceDirect
- Ultrasound imaging in reproductive medicine advances in infertility work-up, treatment, and ART 2014SpringerPart I: Ultrasound Technique -- Ultrasound in Reproductive Medicine: Is It Safe?- Principles of 3D Ultrasound -- Two Dimensional and Three Dimensional Doppler in Reproductive Medicine -- Legal Aspects of Ultrasound Imaging in Reproductive Medicine -- Part II: Ultrasound in Infertility Workup -- The Normal Ovary -- Ovarian Reserve and Ovarian Cysts -- Ultrasound and PCOS -- The Normal Uterus -- Congenital Uterine Anomalies -- Uterine Fibroids -- Endometrial Polyps -- Intrauterine Adhesions -- Sonohysterography (SHG) in Reproductive Medicine -- Evaluation of Tubal Patency (HyCoSy, Doppler) -- Hydrosalpinx -- Virtual Hysterosalpingography: A New Diagnostic Technique for the Study of the Female Reproductive Tract -- Ultrasound in Male Infertility -- Part III: Ultrasound in Infertility Treatment -- Ultrasound in Follicle Monitoring for Ovulation Induction/IUI -- 2D Ultrasound in Follicle Monitoring for ART -- 3D Ultrasound in Follicle Monitoring for ART -- Ultrasound Guided Surgical Procedures -- Ultrasound Role in Embryo Transfers -- Ultrasound and Ovarian Hyperstimulation Syndrome -- Pregnancy of Unknown Viability -- Ultrasound Evaluation of Ectopic Pregnancy -- Focused Ultrasound for Treatment of Fibroids.
- Part I: Definitions and Epidemiology -- Definitions and Relevance of Unexplained Infertility in Reproductive Medicine -- Definitions and Epidemiology of Unexplained Male Infertility -- Controversies Surrounding the 2010 World Health Organization Cutoff Values for Human Semen Characteristics and Its Impact on Unexplained Infertility -- Definitions and Epidemiology of Unexplained Female Infertility -- Part II: Pathophysiology: Male -- Sperm Biology from Production to Ejaculation -- Idiopathic Infertility: Survival and Function of Sperm in the Female Reproductive Tract -- Potential Male Etiologies of Unexplained Infertility -- Genetic Basis of Unexplained Male Infertility -- Role of the Immune System in Unexplained Male Infertility -- Oxidative Stress in Unexplained Male Infertility -- Role and Significance of Sperm Function in Men with Unexplained Infertility -- Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility -- Part III: Pathophysiology: Female -- Potential Female Etiologies of Unexplained Infertility -- Oxidative Stress in Unexplained Female Infertility -- Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Female Infertility -- Cervical Hostility and Vaginal pH in Females with Unexplained Infertility -- Role of Endometrial Receptivity in Unexplained Infertility -- Fallopian Tube Dysfunction in Unexplained Infertility -- Subtle Endometriosis and Unexplained Infertility -- Part IV: Evaluation -- Evaluation of Women with Unexplained Infertility -- Evaluation of Men with Unexplained Infertility -- Part V: Expectant, Medical and Surgical Treatment -- The Role of Expectant Management for Couples with Unexplained Infertility -- Treatment and Prognosis of Immunological Factors in Unexplained Male Infertility -- Medication Strategies for the Male with Unexplained Infertility -- Clomiphene Citrate for Women with Unexplained Infertility -- Aromatase Inhibitors in the Treatment of Unexplained Female Infertility -- Gonadotropins for Women with Unexplained Infertility -- Part VI: Assisted Reproductive Techniques and Future Perspectives -- Gonadotropin in Assisted Reproduction: An Evolution Perspective -- Intrauterine Insemination in Unexplained Female Infertility -- Role of In Vitro Fertilization in Unexplained Female Infertility -- Role of Assisted Reproduction Techniques in the Management of Unexplained Male Infertility -- Future Perspectives in the Diagnosis and Management of Unexplained Male Infertility.
- Advances in technology now offer promising solutions to deal with the chronological aging of the cell, tissue or organ to synchronize its existence and its use. This book covers the developments in and benefits of the latest vitrification technology and its extensive applications in reproductive medicine. Protocols of gametes (oocyte and sperm), embryos, blastocysts and ovarian tissue cryopreservation have been reviewed by leaders in the field. In order to address the escalation in cross-border reproductive tourism entailing the transfer of reproductive cells and tissues rather than the patient, the challenges, caution and emerging possibilities of nitrogen vapor shipment of vitrified cells have been discussed. Current perspectives on oocyte banking present the reader with options and solutions to effectively utilize these gametes despite the physiological deterrants. The versatile applications and potential of vitrification of human embryonic stem cells, discussed in the concluding chapter, is an exciting reality offered by vitrification to help overcome numerous stumbling blocks in the management of various disorders.
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