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PsychopharmacologyAccess restricted to Stanford unless otherwise noted

  • 1. Introduction -- 2. Diagnostic assessment -- 3. Diagnostic instruments -- 4. Treatment -- 5. Treatment: coaching adults with ADHD -- 6. Setup and organization of a specialist department.
  • Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs. Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.
  • The book highlights important new research using current state-of-the-art approaches by prominent researchers in the field of depression. A broad range of topics is covered, beginning with a description of the phenotypic features of clinical depression, followed by chapters on the cellular and molecular basis, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered. In this way the volume brings together the key disciplines involved in the neurobiological understanding of depression to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators interested in the present state of depression research.
  • Use of psychotropic drugs has come to dominate clinical practice in psychiatry worldwide--perhaps owing largely to perceived simplicity, ease of use, and apparent efficiency, as well as apparent cost-effectiveness of such treatments. Nevertheless, medicinal treatments for patients with psychiatric disorders are but one component of comprehensive clinical care of complex human problems. Extensively updated since its second edition in 1985, Chemotherapy in Psychiatry, Third Edition, again addresses basic aspects of modern psychopharmacology and clinical applications of drugs used in the treatment of major psychiatric disorders, with major emphasis on psychotic, bipolar, and depressive disorders. The presentation covers descriptions of the main classes of psychotropic drugs, selected information concerning their known action mechanisms and metabolic disposition, and their clinical applications for acute illnesses and to prevent recurrences and long-term morbidity. Also covered are limitations and adverse effects of each type of agent, with emphasis on the fact that all psychotropic medicines have adverse effects that range from annoying to potentially lethal. Chemotherapy in Psychiatry, Third Edition, outlines the need to balance benefits and risks at the level of individual persons. Authoritative, and an important contribution to the literature, Chemotherapy in Psychiatry, Third Edition is an invaluable resource for physicians, scientists, trainees, and policymakers.
  • General principles of psychopharmacotherapy with children and adolescents -- Sympathomimetic amines and central nervous system stimulants -- First generation/typical antipsychotic drugs -- Second generation/atypical and other antipsychotic drugs -- Antidepressant drugs -- Mood stabilizers : lithium carbonate and antiepileptics -- Antianxiety drugs -- Other drugs.
  • Current antipsychotics 2012, Springer
    "Six decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that pharmacological research and pharmaceutical development must now focus on complementary or even alternative mechanisms of action to address unmet medical needs, i.e. poorly treated domains of schizophrenia, improved acceptance by patients, better adherence to medication, safety in psychoses in demented patients, and avoiding cardiac and metabolic adverse effects. The first completely novel mechanisms evolving from our insights into the pathophysiology of psychotic disorders, especially the role of glutamatergic mechanisms in schizophrenia, are now under development, and further principles are on the horizon. This situation, in many respects similar to that when the initial second-generation antipsychotics became available, can be rewarding for all. Preclinical and clinical researchers now have the opportunity to confirm their hypotheses and the pharmaceutical industry may be able to develop really novel classes of therapeutics...Our intention was to capture both the accumulated preclinical and clinical knowledge about current antipsychotics as well as prospects for new and potentially more specific antischizophrenia principles. These efforts should be based on the pathophysiology of the diseases and the affected neurotransmitter systems. Since preclinical research on antipsychotic compounds is only reliable when intimately linked through translational aspects to clinical results, we decided to include clinical science as well. It turned out that that this endeavor could not be covered by a single volume. We [prepared] two volumes: Current Antipsychotics and Novel Antischizophrenia Treatments. These topics cannot really be separated from one another and should be seen as a composite entity despite the somewhat arbitrary separation of contributions into two volumes. The continuing challenges of developing improved and safer antipsychotic medications remain of concern and are discussed in the first volume. The new opportunities for the field to develop and license adjunctive treatments for the negative symptoms and cognitive deficits that are treated inadequately by existing compounds have been incentivized recently and provide the focus for the second volume."--Publisher's description.
  • Section 1: Functional anatomy of the serotonergic system -- Evolution of serotonin : sunlight to suicide / Efrain C. Azmitia -- Genetic organisation of the serotonergic system / Ursula M. D'Souza and Ian W. Craig -- The neuronatomy of the serotonergic system / Jean-Pierre Hornung -- Ultrastructure of the serotonin innervation in mammalian central nervous system / Laurent Descarries, Mustapha Riad and Martin Parent -- Classification and signaling characteristics of 5-HT receptors / Joel Bockaert, Sylvie Claeysen, Aline Dumuis and Philippe Marin -- Distribution of 5-HT receptors in the central nervous system / Guadalupe Mengod, Roser Cort s, M. Teresa Vilar and Daniel Hoyer -- Measuring serotonin activity in vivo in the brains of animals and humans / Charles A Marsden -- Section 2: The neurophysiology of serotonin -- Activity of brain serotonergic neurons in relation to physiology and behavior / Barry L. Jacobs and Casimir A. Fornal -- Electrophysiology of serotonin receptors / Gerard J. Marek -- Tryptophane hydroxylase and serotonin synthesis regulation / Hiroyuki Hasegawa and Kazuhiro Nakamura -- The degradation of serotonin : role of MAO / Marco Bortolato, Kevin Chen and Jean C Shih -- Cellular effects of serotonin in the CNS / Rodrigo Andrade and Sheryl G. Beck -- Serotonergic feedback control / Trevor Sharp -- Tryptophan depletion and serotonin release : a critical reappraisal / Matthijs G.P. Feenstra and Geoffrey van der Plasse -- Serotonin interaction with other transmitter systems / Albert Adell, Anal a Bortolozzi, Llorenc D iaz-Mataix, Noem Santana, Pau Celada, and Francesc Artigas -- Serotonergic regulation of rhythmical activity of the brain, concentrating on the hippocampus / Robert P. Vertes -- 5-HT neurons and central CO 2 chemoreception / Carolin I. Dohle and George B. Richerson --Section 3: Serotonin and behavioural control -- Serotonin and development / Patricia M. Whitaker-Azmitia -- Serotonin and basal sensory : motor control / Robert J. Carey -- Role of the serotonergic system in appetite and ingestion control / Michelle D. Lee and Peter G. Clifton -- Serotonin and sexual behavior / Lynda Uphouse and Jutatip Guptarak -- Serotonin in mood and emotion / Julie G. Hensler -- Serotonin and the neurobiology of anxious states / Christopher A. Lowry and Matthew W. Hale -- Role of Serotonin in Brain Reward and Regulation of Alcohol Drinking Behavior / W. J. McBride -- Role of central serotonin in impulsivity and compulsivity : Comparative studies in experimental animals and humans / TW Robbins & MJ Crockett -- Experimental studies on the role(s) of serotonin in learning and memory functions / Jean-Christophe Cassel -- Social behavior and serotonin / Elif Aysimi Duman and Turhan Canli -- Serotonin in pain and pain control / Claudia Sommer -- Section 4: Serotonin in disease conditions --The Impact of Stress on Serotonergic Neurotransmission / Astrid C.E. Linthorst and Johannes M.H.M. Reul -- Role for serotonin in depression / Gregory V. Carr and Irwin Lucki -- The role of serotonin in drug addiction / Christian P. M ller, Martin E. Pum, Gunter Schumann and Joseph P. Huston -- The serotonergic system in obsessive compulsive disorders / Addy van Dijk, Andre Klompmakers, and Damiaan Denys --The role of serotonin in attention-deficit hyperactivity disorder (ADHD) / Robert D. Oades -- Serotonin and schizophrenia / Boris B. Quednow, Mark A. Geyer, and Adam L. Halberstadt -- Serotonin and serotonin receptors in hallucinogen action / Adam L. Halberstadt and David E. Nichols -- The role of serotonin in cortical development : implications for Autism Spectrum Disorder [ASD] / Christine F. Hohmann and Mary E. Blue -- Serotonin in panic and anxiety disorders / Francisco Silveira Guimar es, H lio Zangrossi Jr., Cristina Marta Del Ben and Frederico Guilherme Graeff -- Serotonin and agression / Isabel M. Quadros, Aki Takahashi and Klaus A. Miczek -- Altered serotonin function in anorexia and bulimia nervosa / Vikas Duvvuri, Ursula F Bailer and Walter H Kaye -- Genetic, epigenetic, and environmental factors in serotonin associated disease conditions / Eva Friedel & Andreas Heinz -- The Behavioral Genetics of Serotonin : Relevance to Anxiety and Depression / Olivia F. O'Leary and John F. Cryan -- Functional pharmacogenetics of serotonin receptors in psychiatric drug action / Olga O. Yevtushenko, Gavin P. Reynolds.
  • Basic aspects of the immunology of neuroinflammation / Wohleb, E.S.; Godbout, J.P. -- Stress and neuroinflammation / Grippo, A.J., Scotti, M.-A.L. -- Role of inflammation in depression : implications for phenomenology, pathophysiology and treatment / Raison, C.L., Miller, A.H. -- Virus infection as a cause of inflammation in psychiatric disorders / Bechter, K. -- Inflammation, neurotoxins and psychiatric disorders / Myint, A.-M. -- Essential fatty acids as potential anti-inflammatory agents in the treatment of affective disorders / Song, C. -- The brain-gut axis : a target for treating stress-related disorders / Scott, L.V., Clarke, G., Dinan, T.G. -- The question of pro-inflammatory immune activity in schizophrenia and the potential importance of anti-inflammatory drugs / Arolt, V., Ambrée, O. -- Inflammation as the cause of the metabolic syndrome in depression / Leonard, B.E. -- Glucocorticoids and inflammation : a double-headed sword in depression? / Horowitz, M.A. ... [et al.] -- Co-morbidity between cardiovascular pathology and depression : role of inflammation -- Halaris, A. -- Inflammatory and oxidative and nitrosative stress cascades as new drug targets in myalgic encephalomyelitis and chronic fatigue syndrome -- Maes, M. -- Peripheral inflammation and cognitive aging -- Lim, A., Krajina, K., Marsland, A.L. -- Inflammation in suicidality : implications for novel treatment options / Janelidze, S., Brundin, L.
  • Making the DSM-5 2013, Springer
  • Classification, causes, and epidemiology. Different types of depression ; Causes of depression ; Epidemiology and natural history -- Depression in different types of patients. Depression in children ; Depression in elderly people ; Depression in women ; Depression in patients with comorbid medical conditions -- Diagnosis. Signs and symptoms of depression ; Differential diagnosis ; The patient examination and interview ; Laboratory tests for co-occurring illnesses -- Principles of therapy. Goals of treatment ; Treatment options ; Choice of treatment ; Practicalities of treatment ; Factors affecting response to treatment -- Medications. Selective serotonin reuptake inhibitors ; Serotonin and norepinephrine reuptake inhibitors ; Monoamine receptor antagonist drugs ; Norepinephrine reuptake inhibitors ; Dopamine reuptake inhibitors ; Tricyclic antidepressants ; Monoamine oxidase inhibitors ; Other drugs ; Specific adverse effects of antidepressants -- Other treatments. Psychotherapy for depression ; Combination psychotherapy and psychopharmacotherapy for depression ; Physical treatments ; Lifestyle and complementary therapies -- Management of treatment nonresponse. Assessment and principles of management ; Definitions: treatment nonresponse and treatment-resistant depression ; Medication strategies ; Psychological treatment strategies ; Physical treatment strategies -- Continuation and maintenance treatment. Goals of continuation/maintenance treatment ; Phases of treatment ; Medication ; Psychological treatments ; Physical treatments ; Risk factors for relapse and recurrence ; Longer-term treatment in practice.
  • The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This bookcontains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinsons disease, Alzheimers disease. Additionally, melatonins therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonins antioxidant role in Duchennes muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science.
  • Metabolic syndrome and schizophrenia : is inflammation the cause? / Leonard, B.E. -- Insulin resistance in bipolar women : effects of mood-stabilizing drugs / Vemuri, M. ... [et al.] -- Obesity and mental illness / Citrome, L.; Vreeland, B. -- Glucose abnormalities in schizophrenia, bipolar and major depressive disorders / Bushe, C. -- Screening for diabetes and cardiovascular risk factors in people with serious mental illness / Holt, R.I.G.; Peveler, R.C. -- Stress axis dysfunction : a common finding in schizophrenia and the metabolic syndrome? / Afzal, A.; Thakore, J. -- Metabolic syndrome in psychiatric inpatients treated for depression / Goethe, J.W.; Szarek, B.L.; Caley, C.F. -- Hyperprolactinaemia associated with antipsychotic medications / Fitzgerald, P.; Dinan, T.G. -- Impact of hyperprolactinaemia on the general health of patients with schizophrenia / Wildgust, H.J.; Kohen, D.
  • Neurogenesis in the Adult Mammalian Brain: How Much Do We Need, How Much Do We Have? /Ilias Kazanis --Neurogenesis and Hippocampal Plasticity in Adult Brain /Yan Gu, Stephen Janoschka, Shaoyu Ge --Adult-Born Neurons in the Olfactory Bulb: Integration and Functional Consequences /Gilles Gheusi, Gabriel Lepousez, Pierre-Marie Lledo --Network, Cellular, and Molecular Mechanisms Underlying Long-Term Memory Formation /Mariana Carasatorre, Víctor Ramírez-Amaya --Neurotrophins and Synaptic Plasticity /Andrea Gómez-Palacio-Schjetnan, Martha L. Escobar --Differential Effects of Stress and Glucocorticoids on Adult Neurogenesis /Timothy J. Schoenfeld, Elizabeth Gould --Effects of Environmental Enrichment Exposure on Synaptic Transmission and Plasticity in the Hippocampus /Michael J. Eckert, Wickliffe C. Abraham --All About Running: Synaptic Plasticity, Growth Factors and Adult Hippocampal Neurogenesis /Carmen Vivar, Michelle C. Potter, Henriette van Praag --The Effect of Systemic Chemotherapy on Neurogenesis, Plasticity and Memory /Peter Wigmore --Novel Insights into Depression and Antidepressants: A Synergy Between Synaptogenesis and Neurogenesis? /Francis Rodriguez Bambico, Catherine Belzung --Deficient Plasticity in the Hippocampus and the Spiral of Addiction: Focus on Adult Neurogenesis /Juan J. Canales --Prolonged Running, not Fluoxetine Treatment, Increases Neurogenesis, but does not Alter Neuropathology, in the 3xTg Mouse Model of Alzheimer's Disease /Michael W. Marlatt, Michelle C. Potter --Hippocampal Neurogenesis and Ageing /Sébastien Couillard-Després --Repair of the CNS Using Endogenous and Transplanted Neural Stem Cells /R. C. Trueman, A. Klein, H. S. Lindgren, M. J. Lelos.
  • Global patterns of nicotine and tobacco consumption / S.K. Hammond -- Nicotine chemistry, metabolism, kinetics and biomarkers / N.L. Benowitz, J. Hukkanen and P. Jacob, 3rd -- Nicotine content and delivery across tobacco products / M.V. Djordjevic and K.A. Doran -- The road to discovery of neuronal nicotinic cholinergic receptor subtypes / A.C. Collins ... [et al.] -- Magnetic resonance imaging studies of cigarette smoking / A. Azizian ... [et al.] -- In vivo brain imaging of human exposure to nicotine and tobacco / A. Sharma and A.L. Brody -- Molecular and cellular mechanisms of action of nicotine in the CNS / J. Barik and S. Wonnacott -- The neuronal pathways mediating the behavioral and addictive properties of nicotine / D.J. Balfour -- Molecular genetics of nicotine metabolism / J.C. Mwenifumbo and R.F. Tyndale -- Sex differences in nicotine action / S. Pogun and G. Yararbas -- Recognising nicotine: the neurobiological basis of nicotine discrimination / J.W. Smith and I.P. Stolerman -- Effects of nicotine in experimental animals and humans: an update on addictive properties / B. Le Foll and S.R. Goldberg -- Discriminative stimulus effects of nicotine in humans / K.A. Perkins -- Rodent models of nicotine withdrawal syndrome / D.H. Malin and P. Goyarzu -- Approaches, challenges, and experience in assessing free nicotine / D.L. Ashley ... [et al.] -- Tobacco industry manipulation of nicotine dosing / G.F. Wayne and C.M. Carpenter -- Pharmacotherapy for tobacco dependence / R.V. Fant ... [et al.] -- Nicotine psychopharmacology: policy and regulatory / J.E. Henningfield and M. Zeller.
  • Non-suicidal self-injury and eating disorders represent significant problems among today's youth and pose unique challenges for clinicians, particularly when they co-occur. This book is a rare resource in that it provides cutting-edge information on the interactions between self-injury and disordered eating, empirically informed treatments for the co-occurrence of these behaviors, and specific topics relevant to understanding nuances in the risk factors, treatment, and prevention of both self-injury and eating disorders. Practitioners, graduate students, and researchers working within this specialized area will find this text to be instrumental in advancing their knowledge and improving the treatment of self-injury in those with eating disorders.
  • This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
  • "Fully updated for its Fifth Edition, Principles and Practice of Psychopharmacotherapy summarizes the latest data on hundreds of drug and device-based therapies and offers practical, evidence-based guidelines and treatment strategies for virtually every psychiatric disorder. Highlights of this edition include expanded coverage of pharmacogenomics, updates on treatments for elderly patients, and discussion of mechanisms of action for drugs used in sleep disorders, especially narcolepsy"--Provided by publisher.
  • Psychopharmacogenetics 2006, Springer
  • Schizophrenia 2014, Springer
    "Schizophrenia: Recent Advances in Diagnosis and Treatment is a major addition to the literature, offering practical, comprehensive coverage of diagnosis and treatment options, genetic issues, neuroimaging, long-term management of schizophrenia, and future directions and predictions of how clinical care of schizophrenia will change. The book is divided into five sections. Section 1 summarizes the present state of knowledge about the diagnosis and treatment of schizophrenia. This includes recent changes in the DSM 5 categorization of schizophrenia and its implications for treatment. Section 2 considers recent discoveries into its pathoetiology, including the status of biological markers, genetics and neuroimaging as they relate to diagnosis and potential novel therapeutic approaches. Section 3 explores the optimization of present therapeutic approaches; novel treatments; and management of the substantial risks associated with both the illness and its present therapies. Section 4 discusses progress in the long-term management of schizophrenia, focusing on biological and psychotherapeutic strategies to improve functioning and facilitate recovery. Section 5 considers future directions and predictions of how diagnosis and treatment of schizophrenia will change. An invaluable addition to the field, Schizophrenia: Recent Advances in Diagnosis and Treatment is a definitive resource that will be of great interest to all clinicians caring for patients with schizophrenia."--Publisher's website.
  • Serotonin and anxiety 2012, Springer
  • GABA[subscript A] receptor subtypes in sedation and hypnosis / Esa R. Korpi -- Sleep hippocampal theta rhythm and sensory processing / Marisa Pedemonte and Ricardo A. Velluti -- Monoaminergic mechanisms in the regulation of sleep-wakefulness: special emphasis on preoptic noradrenergic system / Vijay Ramesh and Velayudhan Mohan Kumar -- REM sleep function and brain monoamine regulation: an application of the search activity concept / Vadim S. Rotenberg -- Role of wakefulness area in the brainstem reticular formation in regulating rapid eye movement sleep / Birendra N. Mallick ... [et al.] -- The mechanistic relationship between NREM sleep and anesthesia / Laura E. Nelson, Nicholas P. Franks, and Mervyn Maze -- Time-dependent psychotropic drug effects: hints of pharmacochronomics, broader than circadian time structures / Haruo Nagayama ... [et al.] -- Melatonin interaction with BZ-Gaba[subscript A] receptors: implications for sleep induction / Lennard P. Niles -- Melatonin: a chronobiotic that not only shifts rhythms / Dieter Kunz and Richard Mahlberg -- Melatonin and human sleep / Irina V. Zhdanova -- Melatonin efficacy to treat circadian alterations of sleep in Alzheimer's disease / Daniel P. Cardinali ... [et al.] -- Pharmacotherapy for seasonal affective disorder / Timo Partonen -- Use and discontinuation of hypnosedative medications / Mirko Petrovic -- Long-term use of sleeping pills in chronic insomnia / Milton Kramer -- Risks of chronic hypnotic use / Daniel F. Kripke -- Effects of psychotropics on driving performance / Henry J. Moller, Colin M. Shapiro, and Leonid Kayumov -- Diagnosis, pathophysiology and treatment of hypersomnias / Sebastiaan Overeem and Michel Billiard -- Chronic disease and sleep architecture pharmacotherapeutic considerations / James J. Herdegen -- Benzodiazepines for sedation in infants and children / Eugene Ng and Vibhuti Shah -- The pharmacological management of fatigue and sleepiness in affective disorders / Karl Doghramji -- Next-day residual effects of sleeping medications on driving ability: a review of the literature / Joris C. Verster, Marinus N. Verbaten, and Edmund R. Volkerts -- Sleep and pain / Wilfred R. Pigeon, Hyung Park, and Michael J. Sateia -- Head injuries and sleep / Chanth Seyone and Babita Kara -- Psychopharmacological management of restless legs syndrome and periodic limb movements in sleep / Raed Hawa ... [et al.] -- A comparison of visual analog scale and categorical ratings in assessing the patient's estimate of sleep quality / Nava Zisapel, Ricardo Tarrasch, and Moshe Laudon -- The pharmacostrategy of treating sleep disorders in Parkinsonism / Jean-Jacques Askenasy -- The neuropharmacology of nightmares / J.F. Pagel -- The night eating syndrome / Grethe Seta Birketvedt and Jon R. Florholmen -- Drug effects on dreaming / Mehmet Yucel Agargun and Hanefi Ozbek -- Sleep problems in primary care / Alan G. Wade -- SSRIs and sleep in man / Sue J. Wilson and David J. Nutt -- Sleep and antipsychotic drugs in schizophrenia patients / Jaime M. Monti and Daniel Monti -- Sleep and epilepsy: from interrelationships to influence of antiepileptic drugs / Antonio Martins da Silva ... [et all.] -- Herbal medicines and sleep / Marcello Spinella.
  • Textbook of psychopharmacology 2009, PsychiatryOnline

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