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PhysiologyAccess restricted to Stanford unless otherwise noted

  • Clinical cases selected from the LANGE Case Files series, edited by Eugene C. Toy, MD.
  • Adipose tissue biology 2012, Springer
    1. Adipocyte Precursors: Developmental Origins, Self-Renewal, and Plasticity / Christian Dani and Nathalie Billon -- 2. Adipocyte Differentiation / José María Moreno-Navarrete and José Manuel Fernández-Real -- 3. Brown Adipose Tissue / Martin Klingenspor and Tobias Fromme -- 4. White Adipose Tissue / Stephane Gesta and C. Ronald Kahn -- 5. Sex Differences in Body Fat Distribution / Alain Veilleux and André Tchernof -- 6. Macrophages and Inflammation / Elise Dalmas, Joan Tordjman, Michèle Guerre-Millo, and Karine Clément -- 7. Adipocyte Growth and Factors Influencing Adipocyte Life Cycle / Srujana Rayalam and Clifton A. Baile -- 8. The Evolution of Mammalian Adipose Tissue / Caroline M. Pond -- 9. Dietary Determinants of Fat Mass and Body Composition / María A. Zulet, María J. Moreno-Aliaga, and J. Alfredo Martínez -- 10. The Genetic Determinants of Common Obesity-Susceptibility / Ruth J.F. Loos -- 11. Early Origins of Obesity and Developmental Regulation of Adiposity / Shalini Ojha and Helen Budge.
  • Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F.E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts. You can also access the complete contents online at Deepen your grasp of the physiological principles that underlie visual acuity, color vision, ocular circulation, the extraocular muscle, and much more.
  • This book contains the Proceedings of the 3rd International Conference on Cognitive Neurodynamics held in Japan, June 9-13, 2011. It reviews the progress in this field since the first ICCN in 2007. The participants were treated to an exciting and stimulating conference that left everyone with an enthusiastic vision for the future. The discussed topics in this book include: Neural coding and realistic neural network dynamics, Neural population dynamics, Firing Oscillations and Patterns in Neuronal Networks, Brain imaging, EEG, MEG, Sensory and Motor Dynamics, Global cognitive function, Multi-scalar Neurodynamics - from Physiology to Systems Theory, Neural computing, Emerging Technologies for Brain Computer Interfaces, Neural dynamics of brain disorders.
  • Appetite control 2012, Springer
    The volume Appetite Control provides a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism. During the last decade, research in this area has produced a remarkable wealth of information and has characterized the function of numerous peptides, transmitters, and receptors in appetite control. Dysfunction of these circuits leads to obesity, a growing health concern. However, the plethora of mechanistic information is in marked contrasts to an almost complete lack of anti-obesity drugs that meet the safety standards required for the chronic therapy of morbid obesity. Consequently, ongoing research aims to identify additional targets and agents for a pharmacological intervention. Thus, the mechanisms of appetite control as well as all agents interfering with its control are of considerable practical interest.The authors of the volume are distinguished scientists who are leading experts in the field, and who have contributed important, original data to our understanding of the mechanisms of appetite control. They have quite different scientific backgrounds and, together, they represent all relevant disciplines. Thereby, the topics are presented from different points of view, not exclusively from that of pharmacology and neuroendocrinology. Thus, the volume addresses all scientists who are interested in the field of obesity research and the pathophysiology of appetite control.
  • Arterial chemoreceptors 2006, Springer
    A tribute to Professor Autar Singh Paintal -- Structure of chemoreceptors -- Developmental aspects of chemoreceptors -- Molecular biology of chemoreceptors -- Biophysics of ionic channels in chemoreceptors -- Central integration and systemic effects of chemoreflex -- Mechanisms of chemoreceptions.
  • Part 1. Part I. --Introduction and Applications of Surface EMG --Basic Concepts Concerning Fields and Potential Distributions of Stationary and Moving Point Sources --Generation, Propagation, and Extinction of Single-Fiber and Motor Unit Action Potentials --EMG Imaging: Geometry and Anatomy of the Electrode-Muscle System --Features of the Single-Channel sEMG Signal --Features of the Two-Dimensional sEMG Signal: EMG Feature Imaging --Applications of sEMG in Dynamic Conditions, Ergonomics, Sports, and Obstetrics --Part 2. Part II. --Trunk --Upper Limb --Lower Limb.
  • Peripheral processing -- Mosaic evolution of the mammalian auditory periphery -- A computer model of the auditory periphery and its application to the study of hearing -- A probabilistic account of absolute auditory thresholds and its possible physiological basis -- Cochlear compression: Recent insights from behavioural experiments -- Improved psychophysical methods to estimate peripheral gain and compression -- Contralateral efferent regulation of human cochlear tuning: Behavioural observations and computer model simulations -- Modeling effects of precursor duration on behavioral estimates of cochlear gain -- Is overshoot caused by an efferent reduction in cochlear gain? -- Accurate estimation of compression in simultaneous masking enables the simulation of hearing impairment for normal-hearing listeners -- Modelling the distortion produced by cochlear compression -- Temporal fine structure and pitch -- How independent are the pitch and the interaural-time-difference mechanisms that rely on temporal fine structure information? -- On the limit of neural phase-locking to fine-structure in humans -- Effects of sensorineural hearing loss on temporal coding of harmonic and inharmonic tone complexes in the auditory nerve -- A glimpsing account of the role of temporal fine structure information in speech recognition -- Assessing the possible role of frequency-shift detectors in the ability to hear out partials in complex tones -- Pitch perception: Dissociating frequency from fundamental-frequency discrimination -- Pitch perception for sequences of impulse responses whose scaling alternates at every cycle -- Putting the tritone paradox into context: insights from neural population decoding and human psychophysics -- Enhancement and perceptual compensation -- Spectral and level effects in auditory enhancement -- Enhancement of increments in spectral amplitude: further evidence for a mechanism based on central adaptation -- Differential sensitivity to appearing and disappearing objects in complex acoustic scenes -- Perceptual compensation when isolated test words are heard in room reverberation -- A new approach to sound source identification -- Binaural processing -- Maps of ITD in the Nucleus Laminaris of the Barn Owl --The influence of the envelope waveform on binaural tuning of neurons in the inferior colliculus and its relation to binaural perception -- No evidence for ITD-specific adaptation in the frequency following response -- Interaural time difference thresholds as a function of frequency -- Interaural time processing when stimulus bandwidth differs at the two ears -- Neural correlates of the perception of sound source separation -- When and how envelope "rate-limitations" affect processing of interaural temporal disparities conveyed by high-frequency stimuli -- The sound source distance dependence of the acoustical cues to location and their encoding by neurons in the inferior colliculus: implications for the Duplex theory -- Cochlear contributions to the precedence effect -- Off-frequency BMLD: the role of monaural processing -- Measuring the apparent width of auditory sources in normal and impaired hearing -- Psychophysics of human echolocation -- Speech and temporal processing -- Formant-frequency variation and its effects on across-formant grouping in speech perception -- Do we need STRFs for cocktail parties? - On the relevance of physiologically motivated features for human speech perception derived from automatic speech recognition -- Modeling speech intelligibility in adverse conditions -- Better temporal neural coding with cochlear implants in awake animals -- Effects of auditory nerve refractoriness and adaptation on auditory perception -- Robust cortical encoding of slow temporal modulations of speech -- Wideband monaural envelope correlation perception -- Detection thresholds for amplitude modulations of tones in budgerigar (Melopsittacus undulatus) -- Phase discrimination ability in Mongolian gerbils provides evidence for possible processing mechanism of mistuning detection -- Auditory cortex and beyond -- Stimulus-specific adaptation beyond pure tones -- Mapping tonotopy in human auditory cortex -- Cortical activity associated with the perception of temporal asymmetry in ramped and damped noises -- Cortical representation of the combination of monaural and binaural unmasking -- Processing of short auditory stimuli: The Rapid Audio Sequential Presentation paradigm (RASP) -- Integration of auditory and tactile inputs in musical meter perception -- A dynamic system for the analysis of the acoustic features and valence of aversive sounds in the human brain -- Auditory scene analysis -- Can comodulation masking release occur when frequency changes would promote perceptual segregation of the on-frequency and flanking bands? -- Illusory auditory continuity despite neural evidence to the contrary -- High-acuity spatial stream segregation -- How early aging and environment interact in everyday listening: From brainstem to behaviour through modeling -- Energetic and informational masking in a simulated restaurant environment -- A computational model for the dynamic aspects of primitive auditory scene analysis -- A naturalistic approach to the cocktail party -- Temporal coherence and the streaming of complex sounds.
  • Introduction -- Understanding Accreditation and Certification in Musculoskeletal Ultrasound -- Choosing Ultrasound Equipment -- Knobology -- Tissue Scanning -- Hand and Fingers -- Wrist -- Elbow -- Shoulder -- Foot and Toes -- Ankle -- Knee -- Hip -- Groin -- Ultrasound Guidance of Injections -- Rheumatologic Findings.
  • Principles of cell function -- Homeostasis of body fluids -- Signal transduction, membrane receptors, second messengers, and regulation of gene expression -- The nervous system: introduction to cells and systems -- Generation and conduction of action potentials -- Synaptic transmission -- The somatosensory system -- The special senses -- Organization of motor function -- Higher functions of the nervous system -- The autonomic nervous system and its central control -- Sketetal muscle physiology -- Cardiac muscle -- Smooth muscle -- Overview of circulation -- Elements of cardiac function -- Properties of the vasculature -- Regulaiton of the heart and vasculature -- Integrated control of the cardiovascular system -- Structure and function of the respiratory system -- Mechanical properties of the lung and chest wall: static and dynamic -- Ventilation (V̇), perfusion (Q̇), and V̇/Q̇ relationships -- Oxygen and carbon dioxide transport -- Control of respiration -- Nonrespiratory functions of the lung -- Functional anatomy and general principles of regulation in the gastrointestinal tract -- The cephalic, oral, and esophageal phases of the integrated response to a meal -- The gastric phase of the integrated response to a meal -- The small intestinal phase of the integrated response to a meal -- The colonic phase of the integrated response to a meal -- Transport and metabolic functions of the liver -- Elements of renal function -- Solute and water transport along the nephron: tubular function -- Control of body fluid osmolality and volume -- Potassium, calcium, and phosphate homeostasis -- Role of the kidneys in the regulation of acid-base balance -- Introduction to the endocrine system -- Hormonal regulation of energy metabolism -- Hormonal regulation of calcium and phosphate metabolism -- The hypothalamus and pituitary gland -- The thyroid gland -- The adrenal glands -- The male and female reproductive systems.
  • Mechanics of hard tissue / J. Lawrence Katz -- Musculoskeletal soft tissue mechanics / Richard L. Lieber, Thomas J. Burkholder -- Joint-articulating surface motion / Kenton R. Kaufman, Kai-Nan An -- Joint lubrication / Michael J. Furey -- Analysis of gait / Roy B. Davis, III, Sylvia Ounpuu, Peter A. DeLuca -- Mechanics of head/neck / Albert I. King, David C. Viano -- Biomechanics of chest and abdomen impact / David C. Viano, Albert I. King -- Cardiac biomechanics / Andrew D. McCulloch -- Heart valve dynamics / Ajit P. Yoganathan, Jack D. Lemmon, Jeffrey T. Ellis -- Arterial macrocirculatory hemodynamics / Baruch B. Lieber -- Mechanics of blood vessels / Thomas R. Canfield, Philip B. Dobrin -- The venous system / Artin A. Shoukas, Carl F. Rothe -- Mechanics, molecular transport, and regulation in the microcirculation / Aleksander S. Popel, Roland N. Pittman -- Mechanics and deformability of hematocytes / Richard E. Waugh, Robert M. Hochmuth -- Mechanics of tissue/lymphatic transport / Geert W. Schmid-Schonbein, Alan R. Hargens -- Modeling in cellular biomechanics / Alexander A. Spector, Roger Tran-Son-Tay -- Cochlear mechanics / Charles R. Steele ... [et al.] -- Vestibular mechanics / Wallace Grant -- Exercise physiology / Arthur T. Johnson, Cathryn R. Dooly -- Factors affecting mechanical work in humans / Ben F. Hurley, Arthur T. Johnson.
  • Contribution of adipose tissue to health span and longevity / Huffman, D.M., Barzilai, N. -- Obesity paradox during aging / Chapman, I.M. -- Central control of food intake in aging / Kmiec, Z. -- Changes in food intake and its relationship to weight loss during advanced age / McDonald, R.B., Ruhe, R.C. -- Changes in body composition in response to challenges during aging in rats / Wolden-Hanson, T. -- New haystacks reveal new needles : using Caenorhabditis elegans to identify novel targets for ameliorating body composition changes during human aging / Wolkow, C.A. -- Sarcopenia : prevalence, mechanisms, and functional consequences / Berger, M.J., Doherty, T.J. -- mTOR signaling as a target of amino acid treatment of the age-related sarcopenia / D'Antona, G., Nisoli, E. -- Mitochondrial theory of aging in human age-related sarcopenia / Parise, G., De Lisio, M. -- Exercise as a calorie restriction mimetic : implications for improving healthy aging and longevity / Huffman, D.M. -- Clinical, cellular and molecular phenotypes of aging bone / Syed, F.A. ... [et al.].
  • The administration of intravenous fluids is one of the most common and important therapeutic practices in the treatment of surgical, medical and critically ill patients. The international literature accordingly contains a vast number of works on fluid management, yet there is still confusion as to the best options in the various situations encountered in clinical practice.The purpose of this volume is to help the decision-making process by comparing different solution properties describing their indications, mechanisms of action and side-effects according to physiologic body water distribution, electrolytic and acid-base balance, and to clarify which products available on the market represent the best choice in different circumstances. The book opens by discussing in detail the concepts central to a sound understanding of abnormalities in fluid and electrolyte homeostasis and the effect of intravenous fluid administration. In the second part of the monograph, these concepts are used to explain the advantages and disadvantages of solutions available on the market in different clinical settings. Body Fluid Management: From Physiology to Therapy will serve as an invaluable decision-making guide, including for those who are not experts in the subject.
  • "Save time identifying and diagnosing pathology specimens with High Yield Bone and Soft Tissue Pathology, edited by Drs. Andrew Horvai and Thomas Link. Part of the High-Yield Pathology Series, this title is designed to help you review the key pathologic features of bone and soft-tissue malformations, recognize the classic look of each disease, and quickly confirm your diagnosis. Its templated format, excellent color photographs, concise bulleted text, and authoritative content will help you accurately identify more than 160 discrete disease entities. Online access to complete text, image bank, and more at makes this an ideal reference for on-the-go pathologists."--Publisher's website.
  • An updated edition of the classic Methods in Cell Biology volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come.
  • Calcium signaling. 2nd ed. 2006, CRCnetBASE
  • Summary --Introduction --Direct evidence - the digital approach --Fluorescence-based visualisation --Aequorin-based measurements --Measurement of calcium transport across membranes --Molecular biology based approaches --Manipulation of calcium --Calcium-induced function --Calcium signalling in cardiac myocytes --Calcium signalling in red blood cells --Perspective --Calcium Signalling Methodology --Non-linear and ultra high-speed imaging for explorations of the murine and human heart --A system for optical high resolution screening of electrical excitable cells --Concepts for optical high content screens of excitable primary isolated cells --A primary culture system for sustained expression of a calcium sensor in preserved adult rat ventricular myocytes --Calcium imaging of individual erythrocytes: Problems and approaches --Calcium Signalling in Cardiac Myocytes --Reduced Cardiac L-Type Ca²+ Current in Cav€ ₂ -/- Embryos Impairs Cardiac Development and Contraction With Secondary Defects in Vascular Maturation --Overexpression of junctin causes adaptive changes in cardiac myocyte Ca²+ signaling --Remodelling of Ca²+ handling organelles in adult rat ventricular myocytes during longterm culture --Functional and morphological preservation of adult ventricular myocytes in culture by sub-micromolar cytochalasin D supplement --Calcium Signalling in Red Blood Cells --The non-selective voltage-activated cation channel in the human red blood cell membrane: reconciliation between two conflicting reports and further characterisation --Ion channels in the human red blood cell membrane: Their further investigation and physiological relevance --Prostaglandin E₂ activates channelmediated calcium entry in human erythrocytes: An indication for a blood clot formation supporting process --Functional NMDA receptors in rat erythrocytes --Stimulation of human red blood cells leads to Ca²+-mediated intercellular adhesion --Lysophospatidic acid induced red blood cell aggregation in vitro --Regulation of phosphatidylserine exposure in red blood cells --Cation Channels in Erythrocytes - Historical and Future Perspective.
  • The processes of adaptation and maladaptation play an important role in the pathogeny of serious cardiovascular diseases, such as hypertension, valvular diseases, congenital heart disease, myocardial infarction and different cardiomyopathies as well as during adaptation to exercise and high altitude hypoxia. This volume incorporates the rapidly developing basic and clinically relevant information on adaptive mechanisms, thereby contributing to the better understanding of possible prevention and therapy of life-threatening cardiovascular diseases. The first section of this volume focuses on developmental aspects of cardiac adaptation, including chapters on comparative and molecular aspects of cardiac development, prenatal and postnatal developments, coronary vascular development, and ontogenetic adaptation to hypoxia, as well as cardiac and arterial adaptation during aging. The second section is devoted to cardiac adaptations to overload on the heart, centered around the mechanisms of cardiac hypertrophy due to pressure overload, volume overload, exercise, gender difference, high altitude, and different pathological situations. The third section of this volume highlights the roles of sympathetic nervous system with respect to [alpha]-adrenoceptor and [beta]-adrenoceptor mechanisms in the development of cardiac hypertrophy. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.
  • The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees. This book should stimulate future translational research targeted towards discovery and development for preventing, limiting and reversing bad remodeling over the next few decades, with the ultimate goal of preventing progression to systolic and/or diastolic heart failure. The chapters suggest potential novel strategies that should receive attention for translating basic research knowledge to application in patients at the bedside.
  • Overview of the respiratory system / S.C. Wood -- Control of respiration in aquatic vertebrates: Gas transport and gill function in water-breathing fish / S.F. Perry ... [et al.]. Patterns of acid-base regulation during exposure to hypercarbia in fishes / C.J. Brauner and D.W. Baker. Buoyancy control in aquatic vertebrates / B. Pelster. Gas exchange and control of respiration in air-breathing teleost fish / M.L. Glass and F.T. Rantin. Effects of temperature on cardiac function in teleost fish / A.L. Kalinin ... [et al.]. Physiological evidence indicates lungfish as a sister group to the land vertebrates / M.L. Glass. Aestivation in amphibians, reptiles, and lungfish / M.L. Glass, J. Amin-Naves, and G.S.F. da Silva -- Evolution of pulmonary mechaincs and respiratory control: Trade-offs in the evolution of the respiratory apparatus of chordates / S.F. Perry, W. Klein, and J.R. Codd. Environmental selection pressures shaping the pulmonary surfactant system of adult and developing lungs / S. Orgeig and C.B. Daniels. Midbrain structures and control of ventilation in amphibians / L.H. Gargaglioni and L.G.S. Branco. Comparative aspects of hypoxia tolerance of the ectothermic vertebrate heart / H. Gesser and J. Overgaard. Control of the heart and of cardiorespiratory interactions in ectothermic vertebrates / E.W. Taylor and T. Wang. The endocrine-paracrine control of the cardiovascular system / B. Tota and M.C. Cerra. Stoking the brightest fires of life among vertebrates / Raul K. Suarez and Kenneth C. Welch -- Respiratory physiology of birds : metabolic control: Prenatal development of cardiovascular regulation in avian species / J. Altimiras, D.A. Crossley II, and E. Villamor. Control of breathing in birds : implications for high-altitude flight / G.R. Scott and W.K. Milsom -- Mammalian and human physiology: Peripheral chemoreceptors in mammals : structure, function and transduction / P. Kumar. Central chemosensitivity in mammals / L.K. Hartzler and R.W. Putnam. Human exercise physiology / S. Volianitis and Niels H. Secher.
  • Print Material
  • Overview of the cardiovascular system -- Characteristics of cardiac muscle cells -- The heart pump -- Measurements of cardiac function -- Cardiac abnormalities -- The peripheral vascular system -- Vascular control -- Hemodynamic interactions -- Regulation of arterial pressure -- Cardiovascular responses to physiological stresses -- Cardiovascular function in pathological situations -- Answers to study questions.
  • "Today's knowledge of human health demands a multidisciplinary understanding of medically related sciences, and Case Studies in the Physiology of Nutrition answers the call. Dedicated to the integration of nutrition science with physiology, this text cohesively incorporates descriptions of human problems in order to stimulate students' critical thinking about how the body integrates various physiological factors to maintain homeostasis. This textbook uses short story-type case studies about fictional individuals who have health problems in order to address a range of issues in an approachable manner. The studies vary in difficulty, with some being straightforward with very simple answers, while others require in-depth thinking and literature research to solve. Each study presents patient background, symptoms, clinical finding, and questions to ponder. Upon qualifying course adoption, this book also includes a valuable instructor's manual, which provides solutions to exercises, problem analysis, and resolution to each case study."--Publisher's description.
  • Cat primary visual cortex 2002, ScienceDirect
    The concept of cat primary visual cortex / Bertram R. Payne and Alan Peters -- Optical imaging of functional architecture in cat primary visual cortex / Mark Hubener and Tobias Bonhoeffer -- 2-Deoxyglucose architecture of cat primary visual cortex / Siegrid Lowel -- Functional mapping in the cat primary visual cortex using high magnetic fields / Dae-Shik Kim, Timothy Q. Duong, Kamil Ugurbil, and Seong-Gi Kim -- Relationships of LGN afferents and cortical efferents to cytochrome oxidase blobs / Joanne A. Matsubara and Jamie D. Boyd -- Influence of topography and ocular dominance on the functional organization of callosal connections in cat striate cortex / Jaime F. Olavarria -- Essential and sustaining LGN inputs to cat primary visual cortex / Theodore G. Weyand -- Integration of thalmic inputs to cat primary visual cortex / R. Clay Reid, Jose-Manuel Alonso, and W. Martin Usrey -- The emergence of direction selectivity in cat primary visual cortex / Allen L. Humphrey and Alan B. Saul -- Long-range intrinsic connections in cat primary visual cortex / Kerstin E. Schmidt and Siegrid Lowell -- Pharmacological studies on receptive field architecture / Ulf T. Eysel -- Orientation selectivity and its modulation by local and long-range connections in visual cortex / David Somers, Valentin Dragoi, and Mriganka Sur -- Response synchronization, gamma oscillations, and perceptual binding in cat primary visual cortex / Wolf Singer -- The special relationship between B Retinal ganglion cells and cat primary visual cortex / Bertram R. Payne and R. Jarrett Rushmore -- Primary visual cortex within the cortico-cortico-thalmic network / Jack W. Scannell and Malcolm P. Young -- Behavioral analyses of the contributions of cat primary visual cortex to vision / Donald E. Mitchell -- Index.
  • Cell cycle regulation 2006, Springer
  • 1.Human Evolution and Physical Exercise: The Concept of Being "Born to Run" /Livio Luzi --2.Cell Morphology and Function: The Specificities of Muscle Cells /Anna Maestroni --3.The Cell Membrane of the Contractile Unit /Gianpaolo Zerbini --4.Gene Polymorphisms and Athletic Performance /Ileana Terruzzi --5.Nutrients and Whole-Body Energy Metabolism: The Impact of Physical Exercise /Stefano Benedini --6.Mitochondrial and Non-mitochondrial Studies of ATP Synthesis /Roberto Codella --7.Excessive Nutrients and Regional Energy Metabolism /Gianluca Perseghin --8.Muscle Biopsy To Investigate Mitochondrial Turnover /Rocco Barazzoni --9.Introduction to the Tracer-Based Study of Metabolism In Vivo /Andrea Caumo and Livio Luzi --10.Physical Activity and Inflammation /Raffaele Di Fenza and Paolo Fiorina --11.The HPA Axis and the Regulation of Energy Balance /Francesca Frigerio --12.Physical Exercise in Obesity and Anorexia Nervosa /Alberto Battezzati and Simona Bertoli --13.Physical Exercise and Transplantation /Valentina Delmonte, Vincenzo Lauriola, Rodolfo Alejandro and Camillo Ricordi --14.The Baboon as a Primate Model To Study the Physiology and Metabolic Effects of Exercise /Francesca Casiraghi, Alberto Omar Chavez, Nicholas Musi and Franco Folli.
  • Introduction : homeostasis and cellular physiology -- Diffusion and permeability -- Osmotic pressure and water movement -- Electrical consequences of ionic gradients -- Ion channels -- Passive electrical properties of membranes -- Generation and propagation of the action potential -- Ion channel diversity -- Electrochemical potential energy and transport processes -- Passive solute transport -- Active transport -- Synaptic physiology I -- Synaptic physiology II -- Molecular motors and the mechanism of muscle contraction -- Excitation-contraction coupling in muscle -- Mechanics of muscle contraction.
  • Section 1 Historical Introduction to Secreted Cell Stress Proteins as Signalling Proteins -- Discovery of the Cellular Secretion of Cell Stress Proteins -- Discovery of the Agonist Activities of Molecular Chaperones and Protein-Folding Catalysts -- Identification of Cell Stress Proteins in Biological Fluids -- Section 2 Intracellular Trafficking of Molecular Chaperones and its Consequences -- Hsp27 Phosphorylation Patterns and Cellular Consequences -- Evidence on Cholesterol-Controlled Lipid Raft Interaction of the Small Heat Shock Protein HSPB11 -- Hsp70 Chaperone Systems in Vesicular Trafficking -- Pathways of Hsp70 Release: Lessons from Cytokine Secretion -- Nucleolin: A Novel Intracellular Transporter of HSPA1A -- The Hsp90-Based Protein Trafficking System and Linkage to Protein Quality Control -- Section 3 Molecular Chaperones as Cell Surface Receptors and Receptor Ligands -- Cell Surface Molecular Chaperones and the LPS Receptor -- Hsp60: An Unexpected Cell Surface Receptor in Prokaryotes and Eukaryotes -- Pathophysiological Barriers Impeding the Delivery of Heat Shock Protein (HSP)-based Macromolecules and Nanotherapeutics to Solid Tumors -- The Chaperokine Activity of HSPA1A -- Molecular Chaperones and Scavenger Receptors: Binding and Trafficking of Molecular Chaperones by Class F and Class H Scavenger Receptors -- Grp78 (BiP): A Multifunctional Cell Surface Receptor -- Section 4 Extracellular Secretion of Molecular Chaperones in Prokaryotes and Eukaryotes -- Mycobacterium Tuberculosis Hsp60 as a Key Virulence Factor in Tuberculosis -- Hsp90 vs Conventional Growth Factors in Acute and Diabetic Wound Healing -- Circulating Molecular Chaperones in Health and Disease -- Index.
  • Cerebellar learning 2014, ScienceDirect
    Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biologi
  • This book represents the first in a two-volume set on biological rhythms. This volume focuses on supporting the claim that biological rhythms are universal and essential characteristics of living organisms, critical for proper functioning of any living system. The author begins by examining the potential reasons for the evolution of biological rhythms: (1) the need for complex, goal-oriented devices to control the timing of their activities; (2) the inherent tendency of feedback control systems to oscillate; and (3) the existence of stable and powerful geophysical cycles to which all organisms must adapt. To investigate the second reason, the author enlists the help of biomedical engineering students to develop mathematical models of various biological systems. One such model involves a typical endocrine feedback system. By adjusting various model parameters, it was found that creating a oscillation in any component of the model generated a rhythmic cascade that made the entire system oscillate. This same approach was used to show how daily light/dark cycles could cascade rhythmic patterns throughout ecosystems and within organisms.
  • Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more recently, Wnt signaling pathways upon cilia to regulate fate decisions and morphogenesis. Both primary and motile cilia also play crucial roles in the function of the nervous system, including the primary processing of sensory information, the control of body mass, and higher functions such as behavior and cognition, serving as 'antennae' for neurons to sense and process their environment. In this book we describe the structure and function of cilia and the various tissues throughout the brain and spinal cord that are dependent upon cilia for their proper development and function.
  • Circadian rhythms 2005, ScienceDirect
    Genetic approaches to circadian clocks -- Tracking circadian control of gene activity -- Molecular cycles : clock protein rhythms -- Anatomical representation of neural clocks -- Mosaic circadian systems -- Peripheral circadian clocks -- Cell and tissue culture system -- Intercellular signaling -- Photoresponsive clocks -- Sleeping flies -- Circadian biology of populations -- Circadian clocks affecting noncircadian biology.
  • Clinical Application of Neuromuscular Techniques, Volume 2 - The Lower Body discusses the theory and practice of the manual treatment of chronic pain, especially with regards to the soft tissues of the lower body.
  • The mainstay of orthopedic diagnosis continues to be the physical examination of the patient following a thorough history. This convenient pocketbook presents a comprehensive collection of the clinical tests that are used in orthopedic diagnosis, thereby answering the following questions: What tests are available for examining a particular joint, and how are they to be interpreted? What is meant by the name of a test that is mentioned in the literature or in a physician's report? The methodology and interpretation of all relevant test procedures are presented in almost 500 instructive drawings and brief descriptions: Initial tests, Functional tests, Stress tests, Stability tests. Tables on the examination of the spinal column, shoulder joint, and knee joint help in selecting the most suitable examinations. An invaluable aid for physical therapists, orthopedic surgeons, and primary care or emergency room physicians.
  • Clocks and rhythms 2007, Cold Spring Harb Lab Press
    Introduction -- Clockworks -- Posttranscriptional and posttranslational mechanisms -- Genetics of rhythms -- Entrainment and peripheral clocks -- Systems approaches to biological clocks -- Models -- Development, proliferation, and aging -- Neuroanatomy and circuits -- Sleep, seasons, and mood.
  • The body -- Tissues -- General features of the skeleton -- General features of the muscles -- Anatomical terms and their Latin equivalents -- Trunk -- Anatomical terms and their Latin equivalents -- Bones, ligaments and joints -- Muscles, fascias, and special features -- Anatomical terms and their Latin equivalents -- Bones, ligaments, joints -- Muscles, fascias, and special features -- Anatomical terms and their Latin equivalents -- Skull -- Muscles and fascias -- Anatomical terms and their Latin equivalents -- Head and neck -- Upper limb -- Trunk -- Lower limb -- Anatomical terms and their Latin equivalents.
  • Fundamentals -- Temperature, energy -- Blood -- Respiration, acid-base balance -- Kidney, salt and water balance -- Stomach, intestines, liver -- Heart and circulation -- Metabolism -- Hormones -- Neuromuscular and sensory systems.
  • Fundamentals and cell physiology -- Nerve and muscle, physical work -- Autonomic nervous system (ANS) -- Blood -- Respiration -- Acid-base homeostasis -- Kidneys, salt, and water balance -- Cardiovascular system -- Thermal balance and thermoregulation -- Nutrition and digestion -- Hormones and reproduction -- Central nervous system and senses.
  • Introduction : the broad horizons of comparative genomics / James R. Brown -- Advances in next-generation DNA sequencing technologies / Michael L. Metzker -- Large scale phylogenetic reconstruction / Bernard M.E. Moret -- Comparative genomics of viruses using bioinformatics tools / Chris Upton and Elliot J. Lefkowitz -- Archaebacteria and the prokaryote-to-eukaryote transition (and the role of mitochondria therein) / William Martin, Tal Dagan, and Katrin Henze -- Comparative genomics of invertebrates / Takeshi Kawashima ... [et al.] -- Comparative vertebrate genomics / James W. Thomas -- Gaining insight into human population-specific selection pressure / Michael R. Barnes -- Comparative genomics in drug discovery / James R. Brown -- Comparative genomics and the development of novel antimicrobials / Diarmaid Hughes -- Comparative genomics and the development of antimalarial and antiparasitic therapeutics / Emilio F. Merino, Steven A. Sullivan, and Jane M. Carlton -- Comparative genomics in AIDS research / Philippe Lemey, Koen Deforche, and Anne-Mieke Vandamme -- Detailed comparisons of cancer genomes / Timon P.H. Buys ... [et al.] -- Comparative cancer epigenomics / Alice N.C. Kuo ... [et al.] -- G protein-coupled receptors and comparative genomics / Steven M. Foord -- Comparative toxicogenomics in mechanistic and predictive toxicology / Joshua C. Kwekel, Lyle D. Burgoon, and Tim R. Zacharewski -- Comparative genomics and crop improvement / Michael Francki and Rudi Appels -- Domestic animals : a treasure trove for comparative genomics / Leif Andersson.
  • An introduction to fasting, starvation, and food limitation / Marshall D. McCue -- A history of modern research into fasting, starvation, and inanition / Jean-Hervé Lignot and Yvon LeMaho -- Starvation in rotifers : physiology in an ecological context / Kevin L. Kirk -- Drosophila as a model for starvation : evolution, physiology, and genetics / Alen G. Gibbs and Lauren A. Reynolds -- Metabolic transitions during feast and famine in spiders / Johannes Overgaard and Tobias Wang -- Adaptation of the physiological, endocrine, and digestive system functions to prolonged food deprivation in fish / Nadav Bar and Helene Volkoff -- Starvation in subterranean species versus surface-dwelling species : crustaceans, fish, and salamanders / Frédéric Hervant -- Physiological responses to starvation in snakes : low energy specialists / Marshall D. McCue, Harvey B. Lillywhite, and Steven J. Beaupre -- Cardiovascular circuits and digestive function of intermittent-feeding sauropsids / Rike Campen and Matthias Starck -- Thermoregulatory adaptations to starvation in birds / Esa Hohtola -- Fasting in birds : general patterns and the special case of endurance flight / Susanne Jenni-Eiermann and Lukas Jenni -- Tissue-specific mass changes during fasting : the protein turnover hypothesis / Ulf Bauchinger and Scott R. McWilliams -- Seasonal changes in body mass and energy balance in wild small mammals / Xueying Zhang, Xinyu Liu, and Dehua Wang -- Changes in form and function of the gastrointestinal tract during starvation : from pythons to rats / Jehan-Hervé Lignot -- Changes in fatty acid composition during starvation in vertebrates : mechanisms and questions / Edwin R. Price and Teresa G. Valencak -- Physiological responses to fasting in bats / Miriam Ben-Hamo, Agustí Muñoz-Garcia, and Berry Pinshow -- Muscle protein and strength retention by bears during winter fasting and starvation / Hank Harlow -- Seasonal starvation in northern white-tailed deer / Duane E. Ullrey -- Fasting physiology of the pinnipeds : the challenges of fasting while maintaining high energy expenditure and nutrient delivery for lactation / Cory D. Champagne ... [et al.] -- The use and application of stable isotope analysis to the study of starvation, fasting, and nutritional stress in animals / Kent A. Hatch -- Fearing the danger point : the study and treatment of human starvation in the United Kingdom and India, c. 1880-1974 / Kevin Grant -- Quantitative physiology of human starvation : adaptations of energy expenditure, macronutrient metabolism, and body composition / Kevin D. Hall -- Alternate day fasting : effects on body weight and chronic disease risk in humans and animals / Krista A. Varady -- Horizons in starvation research/ Marshall D. McCue.
  • The study and modulation of cortical connections is a rapidly growing area in neuroscience. This unique book by prominent researchers in the field covers recent advances in this area. The first section of the book describes studies of cortical connections, modulation of cortical connectivity and changes in cortical connections with activities such as motor learning and grasping in primates. The second section covers the use of non-invasive brain stimulation to study and modulate cortical connectivity in humans. The last section describes changes in brain connectivity in neurological and psychiatric diseases, and potential new treatments that manipulate brain connectivity. This book provides an up-to-date view of the study of cortical connectivity, and covers its role in both fundamental neuroscience and potential clinical applications.
  • Of the approximately 640 muscles in the human body, over 10% of them are found in the craniofacial region. The craniofacial muscles are involved in a number of crucial non-locomotor activities, and are critical to the most basic functions of life, including vision, taste, chewing and food manipulation, swallowing, respiration, speech, as well as regulating facial expression and controlling facial aperture patency. Despite their importance, the biology of these small skeletal muscles is relatively unexplored. Only recently have we begun to understand their unique embryonic development and the genes that control it and characteristic features that separate them from the skeletal muscle stereotype.This book is the most comprehensive reference to date on craniofacial muscle development, structure, function, and disease. It details the state-of-the-art basic science of the craniofacial muscles, and describes their unique response to major neuromuscular conditions. Most importantly, the text highlights how the craniofacial muscles are different from most skeletal muscles, and why they have been viewed as a distinct allotype. In addition, the text points to major gaps in our knowledge about these very important skeletal muscles and identified key gaps in our knowledge and areas primed for further study and discovery.
  • Deciphering growth 2005, Springer
  • "There has been a long standing controversy in the field of sports nutrition regarding the role of protein and protein metabolism in muscle development and athletic performance. The understanding of protein nutrition has changed dramatically over the last decade and this book aims to clarify and modernize the topic. This book presents the efficacy, safety, and recommendations of protein intake among strength athletes. Including case studies, the text covers historical perspectives of protein use; safety of high protein diets; specific protein types and timing of intake; weight control using protein; protein synthesis and breakdown; and nitrogenous compounds/supplements"--Provided by publisher.
  • Following their own brilliant careers in haeme protein research, the outstanding scientists Jonathan and Beatrice Wittenberg continue to provide inspiration to the research community in the study of oxygen-binding proteins. Their research has provided the intellectual stimulus to bring together scientists from all over the world with the common goal of developing fascinating new ideas and performing innovative experiments. This book is dedicated to Jonathana (TM)s and Beaa (TM)s lifetime careers. It further illuminates the facts and ideas which dot the paths they traced in Biochemistry and Physiology, elaborating on how these landmark achievements were made and how the haeme proteins community still refers to them. With the field of haeme protein science such a flourishing area, the contributors to this book predict Jonathan and Bea, having played such a seminal role, will continue to be key figures for quite some time to come.
  • Progress in Brain Research is a well-established international series examining major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume, concentrates on state-of-the-art of dopamine research: from basic science to clinical applications. It covers topics including thalamostriatal synapses as a substrate for dopamine action; the multilingual nature of dopamine neurons; ethanol-mechanisms along the mesolimbic dopamine system, and much more. Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry, and the behavioral sciences.The most acclaimed and accomplished series in neuroscienceThis volume looks at dopamine researchin the light of the newest scholarly discoveries and insights.
  • Fulltext ClinicalKey
    Approach to Nerve Conduction Studies and Electromyography -- Anatomy and Neurophysiology -- Basic Nerve Conduction Studies -- Late Responses -- Blink Reflex -- Repetitive Nerve Stimulation -- Anomalous Innervations -- Artifacts and Technical Factors -- Basic Statistics for Electrodiagnostic Studies -- Routine Upper Extremity, Facial, and Phrenic Nerve Conduction Techniques -- Routine Lower Extremity Nerve Conduction Techniques -- Basic Overview of Electromyography -- Anatomy for Needle Electromyography -- Basic Electromyography: Analysis of Spontaneous Activity -- Basic Electromyography: Analysis of Motor Unit Action Potentials -- Clinical-Electrophysiologic Correlations: Overview and Common Patterns -- Median Neuropathy at the Wrist -- Proximal Median Neuropathy -- Ulnar Neuropathy at the Elbow -- Radial Neuropathy -- Peroneal Neuropathy -- Femoral Neuropathy -- Tarsal Tunnel Syndrome -- Facial and Trigeminal Neuropathy -- Polyneuropathy -- Amyotrophic Lateral Sclerosis and its Variants -- Atypical Motor Neuron Disorders -- Radiculopathy -- Brachial Plexopathy -- Proximal Neuropathies of the Shoulder and Arm -- Lumbosacral Plexopathy -- Sciatic Neuropathy -- Neuromuscular Junction Disorders -- Myopathy -- Myotonic Muscle Disorders and Periodic Paralysis Syndromes -- Approach to Electrodiagnostic Studies in the Intensive Care Unit -- Approach to Pediatric Electromyography -- Basics of Electricity and Electronics for Electrodiagnostic Studies -- Electrical Safety and Iatrogenic Complications of Electrodiagnostic Studies.
  • The scope of the EMG examination -- Routine clinical electromyography -- Specialized electrodiagnostic studies -- Electrodiagnostic findings in neuromuscular disorders.
  • Field Potential Generation and Current Source Density Analysis / L. Stan Leung -- Current Source Density Analysis of Ongoing Neural Activity: Theory and Application / Yonghong Chen, Mukesh Dhamala, Anil Bollimunta, Charles E. Schroeder, Mingzhou Ding -- The Juxtacellular Recording-Labeling Technique / Didier Pinault -- Neural Recording Using Digital Telemetry / André A. Fenton, Kathryn J. Jeffery, James G. Donnett -- Large-Scale Neural Ensembles in Mice: Methods for Recording and Data Analysis / Hui Kuang, Joe Z. Tsien -- Behavioral Correlates of Neuronal Activity Recorded as Single-Units: Promises and Pitfalls as Illustrated by the Rodent Head Direction Cell Signal / Robert W. Stackman -- Event-Related Potentials of the Cerebral Cortex / Steven L. Bressler -- Multisite Spike-Field Coherence, Theta Rhythmicity, and Information Flow Within Papez's Circuit / Zimbul Albo, Gonzalo Viana Prisco, Robert P. Vertes -- Cognitively Relevant Recoding in Hippocampus: Beneficial Feedback of Ensemble Codes in a Closed Loop Paradigm / Robert E. Hampson, John D. Simeral, Theodore W. Berger, Dong Song, Rosa H. Chan, Vasilis Z. Marmarelis, Sam A. Deadwyler -- An Intact Septo-Hippocampal Preparation for Investigating the Mechanisms of Hippocampal Oscillation / Romain Goutagny, Jesse Jackson, Sylvain Williams -- Targeted Modulation of Neural Circuits: A New Treatment Strategy for Neuropsychiatric Disease / Helen S. Mayberg, Paul E. Holtzheimer.
  • Bonus Student Consult access - included with the text - allows readers to conveniently access the book's content online. These concise and user-friendly references provide crucial knowledge for the early years of medical training, as well as for exam preparation.
  • Part 1.Overview of Non-Cannabinoid Receptors --Overview of Nonclassical Cannabinoid Receptors /Grzegorz Godlewski and George Kunos --Overview of Non-CB1/CB2 Cannabinoid Receptors: Chemistry and Modeling /Evangelia Kotsikorou and Patricia Reggio --Part 2.G-Protein Coupled Receptors --GPR55 in the CNS /Hui-Chen Lu, Jane E. Lauckner, John W. Huffman and Ken Mackie --The Role of GPR55 in Bone Biology /Lauren S. Whyte and Ruth A. Ross --The Role of GPR55 in Cancer /Clara Andradas, María M. Caffarel, Eduardo Pérez-Gómez, Manuel Guzmán and Cristina Sánchez --GPR18 and NAGly Signaling: New Members of the Endocannabinoid Family or Distant Cousins? /Douglas McHugh and Heather B. Bradshaw --Cannabinoid Signaling Through Non-CB1R/Non-CB2R Targets in Microglia /Neta Rimmerman, Ewa Kozela, Rivka Levy, Zvi Vogel and Ana Juknat --Part 3.Ion Channels --Temperature-Sensitive Transient Receptor Potential Channels as Ionotropic Cannabinoid Receptors /Vincenzo Di Marzo and Luciano De Petrocellis --Nonpsychoactive Cannabinoid Action on 5-HT3 and Glycine Receptors /Li Zhang and Wei Xiong --Part 4.Transcription Factors --Peroxisome Proliferator-Activated Receptors and Inflammation /James Burston and David Kendall --Peroxisome Proliferator-Activated Nuclear Receptors and Drug Addiction /Paola Mascia, Gianluigi Tanda, Sevil Yasar, Stephen J. Heishman and Steven R. Goldberg --Part 5.Conclusions/Therapeutic Potential --Conclusions: Therapeutic Potential of Novel Cannabinoid Receptors /Mary E. Abood, Roger G. Sorensen and Nephi Stella.
  • Introduction to the endocrine system -- Endocrine function of the gastrointestinal tract -- Energy metabolism -- Calcium and phosphate homeostasis -- Hypothalamus-pituitary complex -- The thyroid gland -- The adrenal gland -- Life cycle of the male and female reproductive system -- The male reproductive system -- The female reproductive system -- Fertilization, pregnancy, and lactation.
  • Energy balance in motion 2013, Springer
    Introduction, Energy Balance in Animals --Energy Balance --Limits in Energy Expenditure --Energy Expenditure, Physical Activity, Body Weight and Body Composition --Extremes in Energy Intake --Body Weight --Growth, Growth Efficiency and Ageing --Modern Man in Line with Wild Mammals.
  • Enzinger and Weiss's Soft Tissue Tumors is a medical reference on the diagnosis of tumors of the skeletal muscles, connective tissue, fat, and related structures. Microscopic findings are correlated with the latest developments in molecular biology, cytogenetics, and immunohistochemistry, providing you with a comprehensive and integrated approach to the evaluation of soft tissue specimens. Apply the latest advances in surgical pathology thanks to major updates on recently identified pathological entities such as soft tissue angiofibroma and CIC-related sarcomas; coverage of the newest molecular diagnostic techniques and immunohistochemical and molecular genetic features of soft tissue tumors; new chapters on GIST and soft tissue tumors showing melanocytic differentiation; and more. Effortlessly find the information you need with a chapter organization based on the newest surgical pathology concepts and classifications of soft tissue tumors.
  • 1. Chloride ATPase Pumps in Epithelia -- 2. Divalent Anion Transport in Crustacean and Molluscan Gastrointestinal Epithelia -- 3. Heavy Metal Transport and Detoxification by Crustacean Epithelial Lysosomes -- 4. Epithelial Calcium Transport in Crustaceans: Adaptation to Intrinsic and Extrinsic Stressors -- 5. The Cellular Basis of Extreme Alkali Secretion in Insects: A Tale of Two Tissues -- 6. H+, Na+, K+, and Amino Acid Transport in Caterpillar and Larval Mosquito Alimentary Canal -- 7. CFTR-Dependent Anion Transport in Airway Epithelia -- 8. Sulfate and Phosphate Transporters in Mammalian Renal and Gastrointestinal Systems -- 9. Role of H+-K+ ATPase, Na+-K+-2Cl⁻ and Na+-Cl⁻-HCO₃ ⁻ Transporters in Vertebrate Small Intestine -- 10. The H+- and H+, K+-ATPases of the Collecting Duct -- 11. Acid/Base Regulation in Renal Epithelia by H,K-ATPases -- 12. Sodium Transport Mechanisms in the Mammalian Nephron -- 13. Renal Acid-Base Regulation Via Ammonia Transport in Mammals -- 14. Hexose Transport Across Mammalian Epithelia -- 15. Amino Acid Transport by Epithelial Membranes -- 16. Molecular Ontology of Amino Acid Transport.
  • Essential dance medicine 2009, Springer
  • Chapter 1. Overview of the stress response / Marius Locke -- Chapter 2. Transcriptional regulation of the mammalian heat shock genes / Jenny S.L. Ho and J. Timothy Westwood -- Chapter 3. Heat shock proteins and their induction with exercise / Earl G. Noble -- Chapter 4. HSPs and protein synthesis in striated muscle / Donald B. Thomason and Vandana Menon -- Chapter 5. Stress proteins and myocardial protection / Joseph W. Starnes -- Chapter 6. Heat shock proteins and reactive oxygen species -- Karyn L. Hamilton and Scott K. Powers -- Chapter 7. Stress proteins and exercise-induced muscle damage / Anne McArdle and Malcolm J. Jackson -- Chapter 8. Stress proteins and the mitochondrion / David A. Hood, Arne A. Rungi, Marco Colavecchia, Joseph W. Gordon, and Jeremy J. Schneider -- Chapter 9. Gender-specific regulation of HSP70: mechanisms and consequences / Zain Paroo and Earl G. Noble -- Chapter 10. The role of heat shock proteins in modulating the immune response / Pope L. Moseley -- Chapter 11. Stress proteins and applied exercise physiology / Jürgen M. Steinacker and Yuefei Liu.
  • Ancient and early influences / Jack W. Berryman -- The neuromuscular system / Alan J. McComas -- The cardiovascular system / Loring B. Rowell -- The respiratory system / Jerome A. Dempsey and Brian J. Whipp -- The autonomic nervous system / Charles M. Tipton -- The oxygen transport system and maximal oxygen uptake / Jere H. Mitchell and Bengt Saltin -- The metabolic systems: aerobic metabolism and substrate utilization in exercising skeletal muscle / R. James Barnard and John O. Holloszy -- The metabolic systems: anaerobic metabolism (glycolytic and phosphagen) / George A. Brooks and L. Bruce Gladden -- The endocrine system: metabolic effects of the pancreatic, adrenal, thyroidal, and growth hormones / Michael C. Riddell ... [et al.] -- The temperature regulatory system / Elsworth R. Buskirk -- The renal system / Jacques R. Poortmans and Edward J. Zambraski -- The gastrointestinal system / Carl V. Gisolfi
  • Anatomy of joints, general considerations and principles of joint examination / George V. Lawry, Dennis Bewyer -- The shoulder / Murray J. Beuerlein , Michael D. McKee, Adel Fam -- The elbow / George V. Lawry, Terry Axelrod, Elizabeth Grigoriadis -- The wrist and hand / Arthur A.M. Bookman, Herbert P. von Schroeder, Adel Fam -- The hip / Hans J. Kreder -- The knee / Hans J. Kreder and Gillian Hawker -- The ankle and foot / Gregory W. Choy, David Stephen, Adel Fam -- The spine / George Lawry ... [et al.] -- The temporomandibular joint / Michael B. Goldberg ... [et al.] -- Principles of joint and periarticular aspirations and injections / Gillian Hawker, Elizabeth Grigoriadis, Adel G. Fam.
  • Fibromyalgia definition and epidemiology -- Pathophysiology of fibromyalgia -- Assessment and diagnosis -- Headache -- Chronic fatigue syndrome -- Irritable bowel syndrome -- Sleep disturbance -- Depression and anxiety -- Obesity and metabolic syndrome -- Published recommendations -- Medication treatments -- Non-medication treatments -- Nutritional supplements -- Clinical handouts -- Fibromyalgia and pregnancy -- Fibromyalgia in seniors -- Gender and ethnic issues.
  • Fish bioacoustics 2008, Springer
    Introduction to fish bioacoustics / Richard R. Fay, Arthur N. Popper, and Jacqueline F. Webb -- Hearing and acoustic behavior: basic and applied considerations / Arthur N. Popper and Carl R. Schilt -- Structures and functions of the auditory nervous system of fishes / Richard R. Fay and Peggy L. Edds-Walton -- Evolution of peripheral mechanisms for the enhancement of sound reception / Christopher B. Braun and Terry Grande -- Bioacoustics and the lateral line system of fishes / Jacqueline F. Webb, John C. Montgomery, and Joachim Mogdans -- Orientation to auditory and lateral line stimuli / Olav Sand and Horst Bleckmann -- Multipole mechanisms for directional hearing in fish / Peter H. Rogers and David G. Zeddies -- Vocal-acoustic communication: from neurons to behavior / Andrew H. Bass and Friedrich Ladich -- Active and passive acoustics to locate and study fish / David A. Mann, Anthony D. Hawkins, and J. Michael Jech.
  • Folding for the synapse 2011, Springer
    Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.
  • Functional independence : a lifelong goal -- Theories affecting development -- Motor development -- Motor control and motor learning -- Evaluation of function, activity, and participation -- Skeletal system changes -- Muscle system changes -- Cardiovascular and pulmonary systems changes -- Nervous system changes -- Sensory system changes -- Vital functions -- Posture and balance -- Locomotion -- Prehension -- Health and fitness.
  • 1.Introduction --2.Force Vector --3.Moment and Torque Vectors --4.Statics: Systems in Equilibrium --5.Applications of Statics to Biomechanics --6.Introduction to Dynamics --7.Linear Kinematics --8.Linear Kinetics --9.Angular Kinematics --10.Angular Kinetics --11.Impulse and Momentum --12.Introduction to Deformable Body Mechanics --13.Stress and Strain --14.Multiaxial Deformations and Stress Analyses --15.Mechanical Properties of Biological Tissues --Appendex A.Plane Geometry --Appendix B.Vector Algebra --Appendix C.Calculus.
  • Transport processes represents important life sustaining elements in all humans. These include mass transfer processes, including gas exchange in the lungs, transport across capillaries and alveoli, transport across the kidneys, and transport across cell membranes. These mass transfer processes affect how oxygen and carbon dioxide are exchanged in your bloodstream, how metabolic waste products are removed from your blood, how nutrients are transported to tissues, and how all cells function throughout the body. A discussion of kidney dialysis and gas exchange mechanisms is included. Another element in biomedical transport processes is that of momentum transport and fluid flow. This describes how blood is propelled from the heart and throughout the cardiovascular system, how blood elements affect the body, including gas exchange, infection control, clotting of blood, and blood flow resistance, which affects cardiac work. A discussion of the measurement of the blood resistance to flow (viscosity), blood flow, and pressure is also included. A third element in transport processes in the human body is that of heat transfer, including heat transfer inside the body towards the periphery as well as heat transfer from the body to the environment. A discussion of temperature measurements and body protection in extreme heat conditions is also included.
  • The cell -- The cell membrane -- Genes and proteins -- Control systems and homeostasis -- Functional anatomy of the nervous system -- Resting membrane potential -- Membrane excitation and action potential -- Electrophysiology of ion channels -- Conduction of the action potential -- Sensory mechanisms -- Transmission of neuromuscular junctions and synapes -- The autonomic nervous system -- Functional anatomy of muscle -- Mechanism of muscle contraction -- Characteristics of muscle contraction -- Muscle elasticity -- Muscle mechanics -- Smooth muscle -- Cardiac muscle -- Body fluids and blood -- Red blood cells -- Hemoglobin -- Hemopoiesis -- Hermatinic factors -- Blood grouping and transfusion -- Blood platelets and hemostasis -- Hemostatic balance -- Granulocytes -- Agranulocytes and lymphoid organs -- Immunity, tolerance, and hypersensitivity -- Immune mechanisms -- Cardiac excitation and the electrocardiogram -- Cardiac cycle -- Cardiac output -- Circulatory pathway and hemodynamics -- Capillary exchange and lymphatic circulation -- Chemical and neural control of the cardiovascular system -- Blood pressure regulation -- Coronary circulation -- Cerebral circulation -- Pulmonary and pleural circulation -- Cutaneous, muscle, and splanchnic circulation -- Regulation of body temperature -- Functional anatomy of the respiratory system -- Mechanics of pulmonary ventilation -- Measurements of pulmonary ventilation -- Alveolar ventilation, perfusion, and gas exchange -- Transport of gases -- Neural control of respiratory rhythm -- Chemical control of pulmonary ventilation -- Respiration in unusual environments -- Pulmonary function tests and respiratory disorders -- Functional anatomy of the kidney -- Glomerular filtration and tubular reabsorption -- Renal handling of sodium -- Renal mechanisms determining urine osmolarity -- Body fluid and electrolyte balance -- Renal contribution to acid-base balance -- Renal handling of miscellaneous substances -- Hormones acting on the kidney -- Quantification of renal functions -- Whole body acid-base balance -- Renal syndromes -- Urinary bladder and micturition -- Nutritional needs of the body -- Functions of the mouth and esophagus -- Functions of the stomach -- Functions of the duodenum -- Functions of the small intestine -- Function of the colon -- Gastrointestinal hormones -- Gastrointestinal disorders -- Metabolic pathways -- Mechanism of hormonal action -- Hypothaoamic and pituitary hormones -- Thyroid hormones -- Hormones regulating calcium balance -- Hormones of the adrenal cortex -- Hormones of the adrenal medulla -- Pancreatic hormones and the regulation of blood glucose -- Testicular and ovarian hormones -- Puberty and gametogenesis -- Menstrual cycle -- Sperm transport and fertilization -- Sexual differentiation of the fetus -- Pregnancy -- Parturition and lactation -- Appendix A: Principles of physics in physiology -- Appendix B: Principles of chemistry in physiology -- Appendix C: Abbreviations used in text.
  • Section I. Overview of sleep medicine -- Section II. Anatomy and physiology -- Section III. Sleep disorders and disorders that affect sleep -- Section IV. Patient care and assessment -- Section V. Polysomnography -- Section VI. Interventions and therapeutics -- Section VII. Ancillary procedures -- Section VIII. Pediatrics -- Section IX. Sleep center management -- Section X. Appendix.
  • Gastrointestinal Physiology explains the operation and performance of one of the body's most crucial systems. Using clear, compelling language, the book's presentation makes it easy to absorb the content and integrate it as you learn the physiology of other bodily systems. Written to help you understand essential concepts rather than merely memorize facts, this unique text examines many medically relevant facets of this important body system, including anatomy, pathophysiology, and therapeutics, in concert with physiological information.
  • Basic physiology of the growth hormone/insulin-like growth factor (IGF)-axis / Laura M. Frago and Julie A. Chowen -- Experimental models for understanding the role of insulin-like growth factor-I and its receptor during development / Jose Luis Trejo, Eva Carro, and Deborah J. Burke -- Insulin-like growth factor binding proteins in development / Josef V. Silha and Liam J. Murphy -- Growth hormone, insulin-like growth factors, and the female reproductive system / Carolyn A. Bondy and Jian Zhou -- Skeletal muscle / Ana M. Fernandez and Derek LeRoith -- Cardiovascular and respiratory systems / Åsa Tivesten and Jörgen Isgaard -- Hematopoiesis / Wilson Savino, Salete Smaniotto, and Mireille Dardenne -- Brain development / Gregory J. Popken ... [et al.] -- Regulation of vertebrate sensory organ development : a scenario for growth hormone and insulin-like growth factors action / Amelia Diaz-Casares ... [et al.] -- Role of insulin-like growth factors in neuronal plasticity and neuroprotection / Ignacio Torres Alemán -- Aging and life span / Holly M. Brown-Borg -- Interactions of insulin-like growth factor-I and estrogen in the brain / Pablo Mendez, Gloria Patricia Cardona-Gomez, and Luis Miguel García-Segura -- Cancer / Adda Grimberg -- Genetic basis of proportional short stature / Ángel Campos-Barros, Karen E. Heath, Jesús Argente -- Future perspectives : from stem cells and IGF biology to the clinic / Yvan Arsenijevic.
  • Fulltext ClinicalKey
    This textbook covers the essentials of human physiology and aims to describe complex physiologic principles in language that is easy to read and understand. The content is arranged in 14 units and 84 chapters. It includes new illustrations in color.
  • pt. 1. Tools and techniques in anthropometry : general methods -- pt. 2. Tools and techniques in anthropometry : water, hydration and surface area -- pt. 3. Tools and techniques in anthropometry : muscle -- pt. 4. Tools and techniques in anthropometry : adipose tissue, other compartments and relationships -- pt. 5. Regions and anatomical areas of the body : head and face -- pt. 6. Regions and anatomical areas of the body : limbs, extremities and bones -- pt. 7. Regions and anatomical areas of the body : joints and digits -- pt. 8. Regions and anatomical areas of the body : abdominal and trunk regions -- pt. 9. Regions and anatomical areas of the body : sensory organs -- pt. 10. Regions and anatomical areas of the body : internal organs, other tissues and regions -- pt. 11. Anthropometry of pregnancy : prenatal and postnatal aspects -- pt. 12. Anthropometry of infants and children -- pt. 13. Anthropometry of puberty and adolescence in health and disease -- pt. 14. Anthropometry of middle-aged and aged in health and disease -- pt. 15. Anthropometry in genetic disease and polymorphisms -- pt. 16. Anthropometry in cancer -- pt. 17. Anthropometry in exercise and sport activities -- pt. 18. Anthropometry in metabolic disease and obesity -- pt. 19. Anthropometry in diabetes -- pt. 20. Anthropometry in cardiovascular disease -- pt. 21. Anthropometry in organ disease -- pt. 22. Anthropometry in special conditions and circumstances -- pt. 23. Anthropometry in ethnic groups and cultural and geographical diversity -- pt. 24. Anthropometry and nutrition : general aspects -- pt. 25. Anthropometry and nutrition : micro- and macro-nutrients -- pt. 26. Biomechanical and ergonomic aspects.
  • Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. High Altitude: Human Adaptation to Hypoxia addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude.--Excerpt from abstract.
  • Here is a great reference source for use when preparing for board or re-certifying exams. High Yield Orthopaedics concisely conveys the most important information in the field with the aid of 600 illustrations--250 in full color. The consistent chapter format--covering every topic thoroughly from the pathophysiology and distribution to the symptoms and treatment--presents the material in a way that makes it easy to access and digest. Covers more than 200 topics with 460 illustrations--250 in full color--to provide you with a comprehensive yet focused resource. Emphasizes recognition of entities illustrated on the Board exams with two or more key clinical or pathological figures per writeup to give you the fullest understanding of the material. Presents topics selected based on the analysis of many years of examination experience so you get only the important information. Includes the most accurate information from experts who keep you current. Supplements topics with illustrations, tables, figures, radiographs, and even flow charts and equations to provide you with a visual understanding of the material. Features chapters organized alphabetically by disorder to help you find what you need fast. Conveys the information in a concise, yet structured manner for at-a-glance reference. Provides quick access to authoritative background with two or three critical references per writeup to extend your reading.
  • The human growth curve, canalization and catch-up growth / Noël Cameron -- Growth in infancy and childhood: a pediatric approach / Horacio Lejarraga -- Adolescent growth / Roland Hauspie and Mathieu Roelants -- Puberty / Peter T. Ellison and Meredith W. Reiches -- Endocrine control of growth / Ron G. Rosenfeld -- Nutrition and growth / Nicholas G. Norgan, Barry bogin and Noël Cameron -- Genomics, epigenetics and growth / Geert R. Mortier and Wim Vanden Berghe -- The genetic epidemiology of growth and development / Bradford Towne, Ellen W. Demerath and Stefan A. Czerwinski -- Social and economic effects on growth / Richard H. Steckel -- Environmental effects on growth / Lawrence M. Schell, Kristen L. Knutson and Stephen Bailey -- The evolution of human growt / Barry Bogin -- Early environments, developmental plasticity and chronic degenerative disease / Christopher W. Kuzawa -- Leg length, body proportion, health and beauty / Barry Bogin -- Physical activity as a factor in growth and maturation / Robert M. Malina -- Comparative and evolutionary perspectives on human brain growth / William R. Leonard, J. Josh Snodgrass and Marcia L. Robertson -- Saltation and stasis / Michelle Lampl -- Lectures on human growth / Peter C. Hindmarsh -- Body composition during growth and development / Babette S. Zemel -- The measurement of human growth / Noël Cameron -- Assessment of maturation / Noël Cameron -- Growth references and standards / T.J. Cole.
  • 1.Understanding human motion: a historic review /Reinhard Klette and Garry Tee --pt. I.2D tracking:2.The role of manifold learning in human motion analysis /Ahmed Elgammal and Chan-Su Lee ;3.Recognition of action as a Bayesian parameter estimation problem over time /Volker Krüger ;4.The William Harvey code: mathematical analysis of optical flow computation for cardiac motion /Yusuke Kameda and Atsushi Imiya ;5.Detection and tracking of humans in single view sequences using 2D articulated model /Filip Korč and Václav Hlaváč --pt. II.Learning:6.Combining discrete and continuous 3D trackers /Gabriel Tsechpenakis, Dimitris Metaxas, and Carol Neidle ;7.Graphical models for human motion modelling /Kooksang Moon and Vladimir Pavlović ;8.3D human motion analysis in monocular video: techniques and challenges /Christian Sminchisescu ;9.Spatially and temporally segmenting movement to recognize actions /Richard Green ;10.Topologically constrained idometric embedding /Guy Rosman, Alexander M. Bronstein, Michael M. Bronstein, and Ron Kimmel --pt. III.2D-3D tracking:11.Contours, optic flow, and prior knowledge: cues for capturing 3D human motion in videos /Thomas Brox, Bodo Rosenhahn, and Daniel Cremers ;12.Tracking clothed people /Bodo Rosenhahn, Uwe G. Kersting, Katie Powell, T. Brox, and Hans-Peter Seidel ;13.An introduction to interacting simulated annealing /Jürgen Gall, Bodo Rosenhahn, and Hans-Peter Seidel ;14.Motion capture for interaction environments /Daniel Grest and Reinhard Koch ;15.Markerless motion capture for biomechanical applications /Lars Mündermann, Stefano Corazza, and Thomas P. Andriacchi --pt. IV.Biomechanics and applications:16.Qualitative and quantitative aspects of movement: the discrepancy between clinical gait analysis and activities of daily life /Dieter Rosenbaum and Mirko Brandes ;17. Optimization of human motion exemplified with handbiking by means of motion analysis and musculoskeletal models /Harald Böhm and Christian Krämer ;18.Imitation learning and transferring of human movement and hand grasping to adapt to environment changes /Stephan Al-Zubi and Gerald Sommer ;19.Accurate and model-free pose estimation of crash test dummies /Stefan K. Gehrig, Hernán Badino, and Jürgen Gall --pt. V.Modelling and animation:20.A relational approach to content-based analysis of motion capture data /Meinard Müller and Tido Röder ;21.The representation of rigid body motions in the conformal model of geometric algebra /Leo Dorst ;22.Video-based capturing and rendering of people /Christian Theobalt, Marcus Magnor, and Hans-Peter Seidel ;23.Interacting deformable objects /Matthias Teschner, Bruno Heidelberger, and Matthias Müller-Fischer ;24.From performance theory to character animation tools /Michael Neff and Eugene Fiume.
  • Hypoxia and exercise 2006, Springer
    Hypoxia honoree. -- A tribute to John Burnard West / James S. Milledge. Adventures in High-altitude physiology / John B. West -- Exercise-induced hypoxemia (EIH): causes and consequences. -- Exercise induced arterial hypoxemia: the role of ventilation-perfusion inequality and pulmonary diffusion limitation / Susan R. Hopkins. Intrapulmonary shunt during normoxic and hypoxic exercise in healthy humans / Andrew T. Lovering, Michael K. Stickland, Marlowe W. Eldridge. Exercise-induced arterial hypoxemia: consequences for locomotor muscle fatigue / Lee M. Romer ... [et al.] -- Causes and effects of sleep-disordered breathing. -- Mechanisms of sleep apnea at altitude / William Whitelaw. Control of cerebral blood flow during sleep and the effects of hypoxia / Douglas R. Corfield and Guy E. Meadows. Neural consequences of sleep disordered breathing: the role of intermittent hypoxia / Mary J. Morrell and Gillian Twigg -- Genetic, genomics, and adaptation to high altitude. -- Finding the genes underlying adaptation to hypoxia using genomic scans for genetic adaptation and admixture mapping / Mark D. Shriver ... [et al.] An evolutionary model for identifying genetic adaptation to high altitude / Lorna G. Moore ... [et al.] Hypoxic preconditioning and erythropoietin protect retinal neurons from degeneration / Christian Grimm ... [et al.] --Blocking stress pathways with cell-permeable membranes. -- Blocking stress signaling pathways with cell permeable peptides / Christophe Bonny. JNK pathway as therapeutic target to prevent degeneration in the central nervous system / Mariaelena Repici and Tiziana Borsello. Salvage of ischemic myocardium: a focus on JNK / Hervé Duplain -- The impact of immobilization and hypoxia on skeletal muscle. -- Mitochondrial reactive oxygen species are required for hypoxic hif[alpha] stabilization / M. Celeste Simon. Hypoxia-induced gene activity in disused oxidative muscle / Christoph Däpp ... [et al.] -- Hypoxic vasoregulation: interactions of red cells, endothelium, and smooth muscle. -- Role of the red blood cell in nitric oxide homeostasis and hypoxic vasodilation / Mark T. Gladwin. Expression of the heterotrimeric G protein gi and ATP release are impaired in erythrocytes of humans with diabetes mellitus / Randy Sprague ... [et al.] Red blood cells and hemoglobin in hypoxic pulmonary vasoconstriction / Steven Deem -- Hypoxia: state of the art. -- Dose-response of altitude training: how much altitude is enough? / Benjamin D. Levine, James Stray-Gundersen. The eye at altitude / Daniel S. Morris ... [et al.] Lake Louise consensus methods for measuring the hypoxic ventilatory response / Frank L. Powell -- Future directions in hypoxia research. -- Pulmonary hypertension in high-altitude dwellers: novel mechanisms, unsuspected predisposing factors / Urs Scherrer ... [et al.] Gene huntin in hypoxia and exercise / Kenneth B. Storey.
  • Risk of cardiovascular events during mountain activities / Martin Burtshcer -- Biventricular function at high altitude: implications for regulation of stroke volume in chronic hypoxia / Simon R. Gibbs -- Control of coronary blood flow during hypoxemia / Johnathan D. Tune -- Metabolic consequences of intermittent hypoxia / Christopher P. O'Donnell -- Intermittent hypoxia and cognitive function: implications from chronic animal models / Barry W. Row -- Vascular consequences of intermittent hypoxia / Barbara J. Morgan -- Angiotensin-induced hypoxia in the kidney: functional and structural changes of the renal circulation / Masaomi Nangaku ... [et al.] -- Role of reactive oxygen species in chronic hypoxia-induced pulmonary hypertension and vascular remodeling / Eva Nozik-Grayck and Kurt R. Stenmark -- Hypoxia and placental remodeling / Judith E. Cartwright ... [et. al.] -- Epithelial sodium channels in the adult lung - important modulators of pulmonary health and disease / Ian C. Davis and Sadis Matalon -- Lung interstitial pressure and structure in acute hypoxia / Giuseppe Miserocchi -- Hypoxic inhibition of alveolar fluid reabsorption / Laura A. Dada and Jacob I. Sznajder -- Regulation and role of neuroglobin in cytoglobin under hypoxia / Thorsten Burmester, Frank Gerlach, and Thomas Hankeln -- Molecular insights into the functional role of myoglobin / Daniel J. Garry and Pradeep P.A. Mammen -- Genetic mechanisms underlying regulation of hemoglobin mass / neeraj Agarwal, Victor R. Gordeuk, and Josef T. Prchal -- Control of the respiratory patterns in insects / Timothy J. Bradley -- Effects of insect body size on tracheal structure and function / Scott D. Kirkton -- The role of HIF-1 in hypoxic response in the skeletal muscle / Steven Mason and Randall S. Johnson -- Gene expression in working skeletal muscle / Hans Hoppeler, Stephan Klossner, and Martin Fluck -- The limits of human endurance: what is the greatest endurance performance of all time? Which factors regulate performance at extreme altitude / Timothy David Noakes -- Jim Milledge: hypoxia honoree 2007 / Annabel Nikol -- Exploring mountain medicine and physiology / James S. Milledge -- Carlos Monge Cassinelli: a portrait / Fabiola Leon-Velarde S. and Jean-Paul Richalet.
  • ch. 1. Introduction, p. 1-12 -- ch. 2. Background, p. 13-38 -- ch. 3. Models of Linear Systems, p. 39-56 -- ch. 4. Models of Nonlinear Systems, p. 57-101 -- ch. 5. Identification of Linear Systems, p. 103-123 -- ch. 6. Correlation-Based Methods, p. 125-167 -- ch. 7. Explicit Least-Squares Methods, p. 169-206 -- ch. 8. Iterative Least-Squares Methods, p. 207-250.
  • Pathology and diagnosis of muscular dystrophies / Carmen Navarro, Susana Teijeira, Beatriz San Millan.-- Standards of care for Duehenne muscular dystrophy: brief treat-NMD recommendations / Thomas Sejerson, Kate Bushby on behalf of the TREAT-EU Network of Excellence.-- Genetics and pahtogenesis of distal muscular dystrophies / Bjarne Udd.-- Phenotype variations in early onset Pompe disease: Diagnosis and treatment results with Myozyme [RTM] / Samuel Ignacio Pascual Pascual.-- Diseases of the human mitochondrial oxidative phosphorylation system / Julio Montoya, Ester Lopez-Gallardo, Maria Dolores Herrero-Martin, Inigo Martinze-Romero, Aurora Gomez-Duran, Daivd Pacheu, Magdalena Garreras, Carme Diez-Sanchez, Manuel J. Lopez-Perez, Eduardo Ruiz-Pesini.-- Mitochondrial diseases: a cross-talk between mitrochondrial and nuclear genomes / Antonella Spinazzola, Massimo Zeviani.-- Mitochondrial disorders due to nuclear OXPHOS gene defects / Cristina Ugalde, Maria Moran, Alberto Blazquez, Joaquin Arenas, Miguel A. Martin.-- Coenzyme Q10 deficiencies in neuromuscular diseases / Rafael Artuch, Leonardo Salviati, Sandra Jackson, Michio Hirano, Placido Navas.-- The role of mitochondrial network dynamics in the pathogenesis of Charcot-Marie-Tooth disease / Francese Palau, Anna Estela, David Pla-Martin, Maribel Sanchez-Piris.-- Pathogenesis and treatment of mitochondrial disorders / Salvatore DiMauro, Michio Hirano.-- Biology of peripheral inherited neuropathies: Schwann cell axonal interactions / Michael E. Shy.-- Phenotype and clinical evolution of Charcot-Marie-Tooth disease type 1A duplication / Jose Berciano, Antonio Garcia, Elena Gallardo, Cesar Ramon, Onofre Combarros.-- Genotypes & sensory pheotypes in 2 new X-linked neuropathies (CMTX3 and dSMAX) and dominant CMT/HMN overlap syndromes.-- Natural history and treatment of peripheral inherited neuropathies / Davide Pareyson, Chiara Marchesi.-- Spinal muscular atrophy during human development: where are the early pathogenic findings / Eduardo Tizzano.-- Spinal muscular atrophy / Jeremie Vitte, Ruben Attali, Nasim Warwar, Irena Gurt, Judith Melki.-- Friedreich ataxia: an update on animal models, frataxin function and therapies / Pilar Gonzalez-Cabo, Jose Vicente Llorens, Francesc Palau, Maria Dolores Molto.-- Genetics and pathogenesis of inherited ataxias and spastic paraplegias / Carmen Espinos, Francesc Palau.
  • This book follows a successful symposium organized in June 2009 at the Human Brain Mapping conference. The topic is at the crossroads of two domains of increasing importance and appeal in the neuroimaging/neuroscience community: multi-modal integration, and social neuroscience. Most of our social interactions involve combining information from both the face and voice of other persons: speech information, but also crucial nonverbal information on the person's identity and affective state. The cerebral bases of the multimodal integration of speech have been intensively investigated; by contrast only few studies have focused on nonverbal aspects of face-voice integration. This work highlights recent advances in investigations of the behavioral and cerebral bases of face-voice multimodal integration in the context of person perception, focusing on the integration of affective and identity information. Several research domains are brought together. Behavioral and neuroimaging work in normal adult humans included are presented alongside evidence from other domains to provide complementary perspectives: studies in human children for a developmental perspective, studies in non-human primates for an evolutionary perspective, and studies in human clinical populations for a clinical perspective.
  • Anatomy for the electromyographer / Denise L. Davis and Ernest W. Johnson -- The essentials of the needle EMG exam / Vivek Kadyan, Ernest W. Johnson, and Denise L. Davis -- Basic nerve conduction techniques / Robert J. Weber and Margaret Turk -- Electrophysiology / Jun Kimura -- Instrumentation / Sanjeev D. Nandedkar -- Advanced needle EMG methods / Erik Stålberg -- Quality improvement and reporting in electrodiagnostic medicine / William S. Pease -- Pictorial guide to muscles and surface anatomy / Henry L. Lew and Su-Ju Tsai -- Pictorial guide to nerve conduction techniques / Henry L. Lew and Su-Ju Tsai -- Entrapment neuropathies and other focal neuropathies (including carpel tunnel syndrome) / Lawrence R. Robinson --Evaluation of the patient with suspected peripheral neuropathy / James W. Albers -- Electrodiagnostic approach to patients with suspected radiculopathy / Timothy R. Dillingham -- Evaluation of the patient with suspected myopathy / Albert C. Clairmont, Bakri Elsheikh, and Yousef M. Mohammad -- Neuromuscular complications of critical illness: evaluation of the patient with a suspected critical illness neuromuscular disorder / Daniel M.Clinchot -- Evaluation of the patient with suspected neuromuscular junction disorder / William J. Litchy -- Pediatric considerations in electromyography / Rosalind J. Batley.
  • Life of Ernest Starling 2005, ScienceDirect
  • v. 2 Springer
  • MDCT anatomy body 2011, Springer
    Lungs and Interstitial Network -- Airways -- Pulmonary Arteries and Veins -- Aorta and Supra-aortic Trunks -- Bronchial Arteries and Vena Cava -- Pleura and Pericardium -- Mediastinal Compartments, Lymphatic System, and Esophagus -- Heart and Coronary Arteries -- Chest Wall -- Diaphragm and Abdominal and Pelvic Walls -- Peritoneal Cavity -- Splanchnic Arteries -- Iliac Arteries and Abdominal Aorta -- Renal Arteries -- Inferior Vena Caval System -- Venous Portal Circle -- Abdominal Lymphatic System -- Gastroduodenal Tract -- Small Intestine -- Colon -- Liver -- Biliary System -- Spleen -- Extraperitoneal Spaces -- Pancreas -- Adrenal Glands -- Kidneys and Ureters -- Urinary Bladder -- Bony Pelvis -- Muscular Pelvis and Pelvic Floor -- Pelvic Space -- Female Pelvis: Uterus, Ovaries, and Ligaments -- Prostate and Seminal Vescicles.
  • Mechanisms of memory. 2nd ed. 2010, ScienceDirect
    This book represents the first step at beginning to put together the complex puzzle of the molecular basis of memory. Sweatt creates a framework of thinking about synaptic plasticity and memory at the molecular level; one which recognizes and begins to incorporate this extreme biochemical complexity into our thinking about memory.
  • Fulltext ClinicalKey
    Medical Physiology, in its updated 2nd edition, firmly relates molecular and cellular biology to the study of human physiology and disease. Drs. Walter Boron and Emile Boulpaep and a team of leading physiologists present practical, accurate coverage emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 1400 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject.
  • The book describes how the balance between pro- and anti-inflammatory molecules is related to health and disease. It is suggested that many diseases are initiated and their progress is influenced by inflammatory molecules and a decrease in the production and/or action of anti-inflammatory molecules and this imbalance between pro- and anti-inflammatory molecules seems to have been initiated in the perinatal period. This implies that strategies to prevent and manage various adult diseases should start in the perinatal period. An alteration in the metaolism of essential fatty acids and their anti-inflammatory molecules such as lipoxins, resolvins, protecitns, maresins and nitrolipids seems to play a major role in the pathobiology of several adult diseases. Based on these concepts, novel therapeutic approaches in the management of insulin resistance, obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, lupus, rheumatoid arthritis and other auto-immune diseases are presented. Based on all these evidences, a unified concept that several adult diseases are due to an alteration in the balance between pro- and anti-inflammatory molecules is discussed and novel methods of their management are presented.
  • The Procedure of Muscle Biopsy -- Histological and Histochemical Stains and Reactions -- Normal Muscle -- Histological and Histochemical changes -- Ultrastructural Changes -- Immunohistochemistry and Immunoblotting -- How to Read A Biopsy -- Classification of Neuromuscular Disorders -- Neurogenic Disorders -- Muscular Dystrophies and Allied Disorders I: Duchenne and Becker Muscular Dystrophy -- Muscular Dystrophies and Allied Disorders II: Limb-Girdle Muscular Dystrophies -- Muscular Dystrophies and Allied Disorders III: Congenital Muscular Dystrophies and Associated Disorders -- Muscular Dystrophies and Allied Disorders IV: Emery-Dreifuss Muscular Dystrophy and Similar Syndromes -- Muscular Dystrophies and Allied Disorders V: Facioscapulohumeral, Myotonic and Oculopharyngeal Muscular Dystrophies -- Myopathies with Vacuoles -- Metabolic Myopathies I: Glycogenoses and Lysosomal Myopathies -- Metabolic Myopathies II: Lipid-Related Disorders and Mitochondrial Myopathies -- Myopathies Associated with Systemic Disorders and Ageing -- Ion Channel Disorders -- Myasthenic Syndromes -- Inflammatory Myopathies -- Toxic and Drug-Induced Myopathies -- Appendix 2: Useful Websites.
  • An introduction to muscle development in drosophila / Helen Sink -- The muscle pattern of drosophila / Volker Hartenstein -- Mesoderm formation in the drosophila embryo / Noriko Wakabayashi-Ito and Y. Tony Ip -- Development of the cardiac musculature / Rolf Bodmer -- Development of the somatic gonad and fat bodies / Mark Van Doren -- Development of the larval visceral musculature / Hsiu-Hsiang Lee, Stephane Zaffran and Manfred Frasch -- Development of the larval somatic musculature / Ana Carmena and Mary Baylies -- Muscle morphogenesis: the process of embryonic myoblast fusion / Susan M. Abmayr and Kiranmai S. Kocherlakota -- Muscle attachment sites-where migrating muscles meet their match / Talila Volk -- Neuromuscular development: connectivity and plasticity / Louise Nicholson and Haig Keshishian -- Metamorphosis and the formation of the adult musculature / Devkanya Dutta and K. VijayRaghavan -- Molecular basis of muscle structure / Jim O. Vigoreaux -- Whole genome approaches to studying drosophila muscle development / Eileen E.M. Furlong -- Comparison of muscle development in drosophila and vertebrates / Michael V. Taylor.
  • Part 1. Myofascial pain syndrome -- Myofascial Pain Syndrome / Robert D. Gerwin -- Morphology of Myofascial Trigger Points: What Does a Trigger Point Look Like? / Siegfried Mense -- Introduction / Siegfried Mense and Robert D. Gerwin -- Part 2. Fibromyalgia syndrome -- Fibromyalgia Syndrome: Clinical Aspects and Management / Emma Guymer and Geoffrey O. Littlejohn -- Gender, Genetics, and Other Risk Factors Increasing Vulnerability to Fibromyalgia / Geoffrey O. Littlejohn -- Part 3. Other muscle pain syndromes -- Low Back Pain of Muscular Origin / Robert D. Gerwin -- Masticatory Muscle Pain / Sandro Palla and Mauro Farella -- Inflammatory Myopathies / Ingrid E. Lundberg and Li Alemo Munters -- Whiplash Injury, Muscle Pain and Motor Dysfunction / Jan Dommerholt -- Brain Imaging of Muscle Pain / Sandra Kamping and Herta Flor.
  • Introduction / Siegfried Mense and Robert D. Gerwin -- Functional anatomy of muscle : muscle, nociceptors, and afferent fibers / Siegfried Mense -- Peripheral mechanisms of muscle pain : response behavior of muscle nociceptors and factors eliciting local muscle pain / Siegfried Mense -- Central nervous mechanisms of muscle pain : ascending pathways, central sensitization, and pain-modulating systems / Siegfried Mense -- Referral of musculoskeletal pain / Thomas Graven-Nielsen and Siegfried Mense -- Increased muscle tone as a cause of muscle pain / Siegfried Mense and Alfonse T. Masi -- Reorganized motor control due to muscle pain / Thomas Graven-Nielsen and Lars Arendt-Nielsen.
  • Especially prepared for the international audience, the English language edition of this highly successful handbook describes Professional Applied Kinesiology muscle testing procedures. A departure from the classic understanding of muscle testing for weakness and rehabilitation, these procedures can be used for detecting more subtle, functional abnormalities. Included within the chapters are stretch tests and post-isometric relaxation procedures for the hypertonic, shortened muscle. Muscle anatomy and physiology are briefly recapped in order to enhance reader comprehension. The Muscle Testing Handbook describes testing procedures for almost 100 individual muscles in a unique, quick reference, template approach. In close collaboration with Dr. Garten, the German edition has been adapted for the English-language audience by Dr. Shafer, an American chiropractic colleague. This book is ideal for use by manual therapists, physiotherapists, osteopaths, chiropractors, sports scientists and neurology department staff worldwide. Clearly describes modern muscle test procedures The individual aspects of each muscle are easily compared by the use of well-illustrated templated descriptions A double-page spread design allows the reader a rapid, at-a-glance access to essential information Muscle anatomy and function are succinctly recapped in order to facilitate a complete understanding of the relevance and applicability of the individual test Classic Applied Kinesiology muscle tests for detecting functional abnormalities are well described along with stretch testing and post-isometric relaxation procedures for hypertonic, shortened muscles The importance of postural analysis for the assessment of specific muscle dysfunction is discussed and plainly described Illustrates painful spondylogenic reflex points (areas) for each muscle The role of distal acupuncture points and tendinomuscular meridians in maintaining normal muscle and muscle chain function are noted in accompanying diagrams The most commonly found trigger points, their referred pain patterns and relationship to nearby acupuncture points are clearly illustrated for each muscle Perfect for use in orthopaedics, neurology, general medicine, physiotherapy, chiropractic and osteopathy.
  • Fulltext ClinicalKey
  • Chapter 1. Introduction and Aims -- Chapter 2. Methodology and Material -- Chapter 3. Muscles of Non-Osteichthyan Vertebrates -- Chapter 4. Head and Neck Muscles of Actinopterygians and Basal Sarcopterygians -- Chapter 5. From Sarcopterygian Fish to Modern Humans -- Chapter 6. Head and Neck Muscles of Amphibians -- Chapter 7. Head and Neck Muscles of Reptiles -- Chapter 8. Pectoral and Pectoral Fin Muscles of Actinopterygian and Sarcopterygian Fishes -- Chapter 9. From Sarcopterygian Fish to Modern Humans -- Chapter 10. Pectoral and Forelimb Muscles of Limbed Amphibians and Reptiles -- Chapter 11. General Comments.
  • Muscular dystrophies 2011, ScienceDirect
    Overview of the muscular dystrophies / A.A. Amato and R.C. Griggs -- Dystrophinopathies / L.A. Morrison -- Sarcoglycanopathies / J. Kirschner and H. Lochmüller -- Congenital muscular dystrophies / S.E. Sparks and D.M. Escolar -- The collagen VI-related myopathies : Ullrich congenital muscular dystrophy and Bethlem myopathy / C.G. Bönnemann -- Limb-girdle muscular dystrophy 2A / E. Gallardo, A.Saenz and I.Iilla -- Dysferlinopathies / A.A. Amato and R.H. Brown Jr -- Other limb-girdle muascular dystrophies / A.A. Amato -- Limb-girdle muscular dystrophy 2H and the role of TRIM32 / P.B. Shieh, E. Kudryashova and M.J. Spencer -- Caveolinopathies : translational implications of caveolin-3 in skeletal and cardiac muscle disorders / E. Gazzerro, A. Bonetto, and C. Minetti -- Myofibrillar myopathies / D. Selcen and A.G. Engel -- Emery-Dreifuss muscular dystrophy / M. Puckelwartz and E.M. McNally -- Facioscapulohumeral dystrophy and scapuloperoneal syndromes / R.W. Orrell -- Oculopharyngeal muscular dystrophy / B. Brais -- Myotonic dystrophy types 1 and 2 / T. Ashizawa and P.S. Sarkar -- Distal muscular dystrophies / B. Udd.
  • Musculoskeletal Health in Women aims to provide fitness advice tailored to women. As women are more prone to specific injuries than men are, due to differences in hip and knee anatomy as well as hormonal differences, this book will provides a fully-illustrated and comprehensive overview of all aspects including energy availability (which is affected by eating disorders), osteoporosis, and menstrual function. Its multidisciplinary approach ensures that expertise is provided from disciplines such as psychiatry, physiatry, endocrinology, nutrition, rheumatology, orthopedics, physical therapy and radiology. Written by authors who have extensive experience working with women athletes, Musculoskeletal Health in Women addresses a full spectrum of issues related to the musculoskeletal health of women. It is of primary interest to women athletes and women embarking on a fitness regimen. Health professionals working in this area would also invariably benefit from the advice and guidance provided within these pages.
  • Musculoskeletal imaging 2008, Thieme Book
    1. Tumors -- Osteoma -- Osteoid osteoma -- Enchondroma -- Osteochondoroma (cartilaginous exostosis) --Nonossifying fibroma -- Fibrous dysplasia (Jaffe-Lichtenstein Disease) -- Juvenile bone cyst -- Aneurysmal bone cyst -- Giant cell tumor (Osteoclastoma) -- Synovial chondromatosis (Reichel Syndrome) -- Bone hemangioma -- Paget Diesase (Ostetis Deformans) --Metastases -- Osteosarcoma -- Ewind sarcoma -- Multiple myeloma (plasmacytoma) -- Lymphoma of bone -- Neoplastic vertebral compression fracture -- Soft-tissue hemangioma -- Soft-tissue sarcoma -- Lipoma -- Pigmented villonodular synovitis -- Myositis ossificans -- 2. Inflammatory diseases -- Osteomyelitis -- Brodie abscess -- Rheumatoid arthritis -- Psoriatic arthritis/psoriatic arthropathy -- Septic arthritis -- Gout (gouty arthritis) -- Ankylosing spondylitis -- Spondylitis and spondylodiskitis -- Complex regional pain syndrome -- 3. Degenerative disease -- Osteoarthritis -- Osteochondrosis -- Intervertebral disk herniation -- Spinal canal stenosis -- Spondylolysis/spondylolisthesis -- Implant loosening -- Diffuse idiopathic skeletal hyperostosis -- Neuropathic osteoarthropathy (charcot joint) -- 4. Metabolic disorders -- Osteoporosis -- Rickets -- Osteomalacia -- Hyperparathyroidism -- 5. Developmental disorders -- Madelund deformity -- Hip dysplasia -- Tibia vara (Blount Disease) -- Slipped capital femoral epiphysis -- Club foot (talipes equinovarus) -- Scoliosis -- Osteogenesis imperfecta -- Osteopetrosis (Marble Bone Disease) -- Scheuermann Disease -- 6. Osteonecrosis -- Perthes Disease -- Osteonecrosis of the knee -- Lunatomalacia (Kienbock Disease) -- Femoral head necrosis -- Osteochondritis dissecans -- Bone infarct -- 7. Intra-articular lesions -- Meniscal lesions -- Cruciate ligament tears -- Cartilage lesions -- Labral lesions -- Rotator cuff lesions -- 8. Ligament and tendon injuries -- Lateral ankle ligament rupture -- Achilles tendon rupture -- Avulsion fracture -- Shoulder impingement -- 9. Fractures and dislocations -- Clavicle fracture -- Acromioclavicular separation -- Proiximal humerus fractures -- Shoulder dislocation -- Radial head fracture -- Pediatric condylar fractures -- Distal radius fracture -- scaphoid fracture -- Triquetrum fracture -- Skier's thumb (gamekeeper's thumb) -- Dens fracture -- Femoral neck fracture -- pertrochanteric femoral fracture -- Patella fracture -- Tibial plateau fracture -- Ankle joint fractures -- Calcaneus fracture -- Fractures of the base of the fifth metatarsal -- Occult fracture -- Stress fracture - Pseudarthrosis.
  • Musculoskeletal MRI. 2nd ed. 2009, ClinicalKey
    Basic principles of musculoskeletal MRI -- Marrow -- Tendons and muscles -- Peripheral nerves -- Musculoskeletal infections -- Arthritis and cartilage -- Tumors -- Osseous trauma -- Temporomandibular joint -- Shoulder -- Elbow -- Wrist and hand -- Spine -- Hips and pelvis -- Knee -- Foot and ankle.
  • Edited by Dominik Irnich, MD, this clearly written and fully illustrated multi-contributor volume offers practical, comprehensive coverage of the subject area ranging from the latest scientific research findings to practical usage of current manual therapy techniques. Including the latest information from centres of excellence throughout the world, this new book is suitable for osteopathic physicians, osteopaths, chiropractors, manual therapists, physiotherapists, acupuncturists and massage therapists as well as general physicians working in primary care, physical medicine, rehabilitation, pain management and internal medicine. Offers practical and clinically relevant information to all practitioners and therapists working in the field Edited by an international expert in pain management and trigger point therapy Abundant use of pull-out boxes, line artwork, photographs and tables facilitates ease of understanding Carefully prepared by a worldwide team of clinically active and research oriented contributors to provide helpful and clinically relevant information Presents the latest research findings for many aspects of trigger point therapy Provides a holistic view of patient care including the importance of patient communication and psychological aspects of pain control Provides a handy reference for rapid and effective diagnosis and treatment of trigger points Highlights the 65 most important muscles in a comprehensive practical style which includes anatomy, symptoms, pain patterns, physical examination and strategies for effective treatment Offers an ideal resource for training courses in trigger point injection, osteopathy, manual therapy and acupuncture Suitable for osteopathic physicians, osteopaths, chiropractors, manual therapists, acupuncturists and massage therapists as well as general physicians working in primary care, physical medicine, rehabilitation, pain management and internal medicine.
  • Myopathies 2007, ScienceDirect
  • The first complete and authoritative book on yawning.
  • Musculoskeletal Anatomy is the first title in the brand new Netter's Correlative Imaging series. Series editor and specialist in musculoskeletal imaging Dr. Nancy Major and coauthor, Michael Malinzak, presents Netter's beautiful and instructive paintings and illustrated cross sections created in the Netter style side-by-side with high-quality patient MR images created with commonly used pulse sequences to help you visualize the anatomy section by section. With in-depth coverage and concise descriptive text for at-a-glance information and access to correlated images online, this atlas is a comprehensive reference that's ideal for today's busy imaging specialists. View upper and lower limbs in sagittal, coronal, and axial view MRs of commonly used pulse sequences, each slice complemented by a detailed illustration in the instructional and aesthetic Netter style. Find anatomical landmarks quickly and easily through comprehensive labeling and concise text highlighting key points related to the illustration and image pairings. Correlate patient data to idealized normal anatomy in the approximately 30 cross-sections per joint that illustrate the complexities of musculoskeletal anatomy.
  • Definitions and criteria for stem cells / Leslie P. Weiner -- Neural stem cells and the future treatment of neurological diseases : raising the standard / Jaime Imitola and Samia J. Khoury -- Neural differentiation of human embryonic stem cells / Mirella Dottori and Martin F. Pera -- Generating neurons from stem cells / Andreas Androutsellis-Theotokis ... [et al.] -- Isolation of neural stem and precursor cells from rodent tissue / Yuanyuan Wu ... [et al.] -- Adult rodent spinal cord-derived neural stem cells : isolation and characterization / Lamya S. Shihabuddin -- Adult neural stem cells / Rossella Galli, Angela Gritti, and Angelo L. Vescovi -- Olfactory ensheathing cells : isolation and culture from the neonatal olfactory bulb / Susan C. Barnett and A. Jane Roskams -- Culturing olfactory ensheathing cells from the mouse olfactory epithelium / Miranda Richter, Kathryn Westendorf, and A. Jane Roskams -- Production and characterization of immortal human neural stem cell line with multipotent differentiation property / Seung U. Kim ... [et al.] -- Preparation of neural progenitors from bone marrow and umbilical cord blood / Shijie Song and Juan Sanchez-Ramos --Production of neurospheres from CNS tissue / Gregory P. Marshall II ... [et al.] -- Nuclear transfer to study the nuclear reprogramming of human stem cells / Shigeo Saito ... [ et al.] -- Clonal analyses and cryopreservation of neural stem cell cultures / Angela Gritti, Rossella Galli, and Angelo L. Vescovi -- Telomere neurobiology / Mark P. Mattson, Peisu Zhang, and Aiwu Cheng -- Chromosomal mosaicism in neural stem cells / Suzanne E. Peterson ... [et al.] -- In vitro assays for neural stem cell differentiation : induction of dopaminergic phenotype / Marcel M. Daadi -- In vitro migration assays of neural stem cells / Pascale Durbec .. [et al.] -- Measuring apoptosis in neural stem cells / Brett T. Lund and Eve E. Kelland -- Markers of adult neural stem cells / Eric Wexler -- Differential gene expression in ES-derived neural stem cells by using RT-PCR / Nicole Slawny, Crystal Pacut, and Theresa E. Gratsch -- Microfluidic devices for high-throughput gene expression profiling of single hESC-derived neural stem cells / Yan Chen and Jiang F. Zhong --Electroporation strategies for genetic manipulation and cell labeling / Terence J. Van Raay, Rhonda T. Lassiter, and Michael R. Stark -- Novel and immortalization-based protocols for the generation of neural CNS stem cell lines for gene therapy approaches / Luciano Conti and Elena Cattaneo -- Identification of newborn cells by BrdU labeling and immunocytochemistry in vivo / Sanjay S. Magavi and Jeffrey D. Macklis -- Immunocytochemical analysis of neuronal differentiation / Sanjay S. Magavi and Jeffrey D. Macklis -- Neuroanatomical tracing of neuronal projections with Fluoro-Gold / Lisa A. Catapano, Sanjay S. Magavi, and Jeffrey D. Macklis -- Labeling stem cells in vitro for identification of their differentiated phenotypes after grafting into the CNS / Qi-lin Cao, Stephen M. Onifer, and Scott R. Whittemore -- Optimizing stem cell grafting into the CNS / Scott R. Whittemore ... [et al.] -- Routes of stem cell administration in the adult rodent / Alison E. Willing ... [et al.]
  • Deals with endocrine regulation of the behavioral state control. This title addresses a wide spectrum of sleep/wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management. It provides a summary of important issues in the neuroendocrine correlates of sleep/wakefulness.
  • In this unique book, Dr. Bertorini guides you through more than 100 cases that demonstrate the diagnosis and management of a wide range of common and rare neuromuscular disorders. No other reference boasts such a large array of clinical studies devoted to all areas of this broad topic! Each case study reviews the etiologies, pathogenesis, differential diagnosis, and management of a particular disorder, helping you not only recognize its presentation, but also determine a diagnosis and the best treatment plans for your patients. You₂ll also find expert guidance on the basic mechanisms of neuromuscular disorders, clinical examination, and diagnostic tests--including EMG, muscle biopsy, genetic testing, and more. More than 100 detailed case studies explore both common and rare neuromuscular disorders and the treatment protocols for each, equipping you with the knowledge you need to confidently manage any challenge. Each case includes a summary of important points or highlights of the study. Case studies are arranged either by complaint or by diagnosis so that you can successfully manage your patients with or without an initial diagnosis. Comprehensive coverage of EMGs and nerve conduction studies and other diagnostic tests, including muscle and nerve biopsies and genetic testing, helps you accurately diagnose nerve, muscle, and neuromuscular transmission disorders. Detailed discussions of treatment plans and commonly used drugs enhance your management of autoimmune disorders, painful neuropathy, dysautonomia, and other neuromuscular disorders. A reader-friendly format takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy. More than 350 high-quality illustrations, including full-color patient photographs, biopsies, and EMG tracings, make complex concepts easier to understand and apply.
  • Neuromuscular Disorders presents a multi-disciplinary approach to the management and therapeutic treatment of the full range of neuromuscular disorders and resulting complications. Dr. Tulio Bertorini and a contributing team of the world's leading authorities in the field provide the latest tools and strategies for minimizing disability and maximizing quality of life. Effectively treat your patients using the latest management tools and targeted therapeutic strategies. Manage all neuromuscular disorders as well as resulting complications through comprehensive coverage of diagnosis and evaluations, treatments, and outcomes. Apply the multi-disciplinary approach of an expert in clinical neuromuscular care and a team of world-renown contributors. Easily refer to tools for diagnosis, treatment algorithms, and drug tables included throughout the text. Pinpoint the problem to provide better quality of life for patients.
  • This book use of ultrasound as an alternative to electrodiagnosis in the evaluation of neuromuscular disorders through detailed descriptions and clear illustrations. Drs. Francis Walker and Michael S. Cartwright discuss techniques for visualizing muscles and nerves without painful testing for better patient compliance and more efficient diagnosis. This book covers the use of ultrasound as an alternative to electrodiagnosis for the evaluation of neuromuscular disorders-using illustrations to compare and contrast the two techniques. It provides lucid descriptions of how the clinical and electrodiagnostic examinations can be refined, improved, and enhanced to minimize patient discomfort and to maximize the optimal patient evaluation.
  • Neurotrophic factors 2014, Springer
    This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington's syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.
  • Overview -- Magnesium homeostasis -- Nutrition -- Epidemiology -- Exercise -- Metabolic syndrome -- Cardiovascular disease -- Skeletal diseases and calcium metabolism -- Kidney -- Neurology -- Magnesium in dental medicine -- Magnesium in neurology and psychiatry -- Veterinary medicine.
  • Osteoporosis : a paediatric concern? / R.A. Faulkner, D.A. Bailey -- The biomechanical basis of bone strength development during growth / S.A. Kontulainen ... [et al.] -- The effect of exercise on bone mass and structural geometry during growth / R.M. Daly -- Evidence for an interaction between exercise and nutrition for improved bone health during growth B. Specker, M. Vukovich -- Gene-environmental interactions in the skeletal response to nutrition and exercise during growth / J.-P. Bonjour ... [et al.] -- The effect of energy balance on endocrine function and bone health in youth / C. Zanker, K. Hind -- Risk factors for fractures in normally active children and adolescents / A. Goulding -- Does exercise during growth prevent fractures in later life? / M.K. Karlsson -- Lessons learned from school-based skeletal loading intervention trials : putting research into practice / J.M. Hughes, S.A. Golner, M.A. Petit.
  • Fulltext ClinicalKey
    Section 1. Essentials of bone biology -- The biochemistry of bone : composition and organization / Adele L. Boskey -- Bone remodeling : cellular activities in bone / David W. Dempster, Hua Zhou, Shi Shou Lu -- Assessment of bone turnover in men using biochemical markers / Patrick Garnero, Pawel Szulc -- Fundamentals of mineral homeostasis / David A. Hanley, K. Shawn Davison -- The mechanical properties of bone / David P. Fyhrie -- Essentials of bone biology : assessment of bone architecture / Thomas F. Lang -- Section 2. Development and growth of the male skeleton -- Skeletal growth in males / Qingju Wang, Ego Seeman -- Pubertal growth of the male skeleton / Vincent Gilsanz, Stefano Mora -- The effects of sex steroids on bone growth / Giampiero I. Baroncelli, Silvano Bertelloni -- Nutritional basis of skeletal growth / Connie M. Weaver, Elizabeth Haney -- Physical activity and skeletal growth / Heather M. Macdonald, Heather A. McKay, Melonie Burrows --Section 3. Skeletal genetics -- The genetics of peak bone mass / Luigi Gennari, Robert F. Klein, Serge Ferrari -- Section 4. Aging and the male skeleton -- Age-related changes in bone remodeling and microarchitecture / Roger Zebaze, Ego Seeman -- Markers of bone remodeling and the aging skeleton / Serge Cremers, Christian Meier, Markus J. Seibel -- Alterations in mineral metabolism in the aging male / Shonni J. Silverberg, Bismruta Misra -- Changes in bone size and geometry with aging / Pawel Szulc -- Aging and bone loss / Steven Boonen ... [et al.] -- The effect of age on material properties / Charles H. Turner, Matthew R. Allen, David B. -- Section 5. Nutritional issues -- Calcium, bone strength and fractures / Laura A.G. Armas, Robert P. Heaney, Joan M. Lappe -- Vitamin D and bone / Roger Bouillon ... [et al.] -- Role of dietary protein in bone growth and bone loss / Rene Rizzoli --Section 6. Sex steroids and the skeleton in men -- Section 7. Fractures in men -- Section 8. Metabolic bone disease in men -- Section 9. Diagnostic approach -- Section 10. Therapy.
  • Air and fire : Carl Wilhelm Scheele, Torbern Bergman, the Royal Society of Sciences and the discovery of oxygen in Uppsala in 1772 / Lars-Olof Sundelöf -- Mathematical modeling of the interactiion betwen oxygen, nitric oxide and superoxide / Donald G. Buerk -- Haemoglobin saturation controls the red blood cell mediated hypoxic vasorelaxation / Andrew G. Pinder ... [et al.] -- Blood vessel specific vaso-activity to nitrite under normoxic and hypoxic conditions / Thomas E. Ingram ... [et al.] -- Nitrite-induced improved blood circulation associated with an increase in a pool of RBN-NO with NO bioactivity / Joseph M. Rifkind ... [et al.] -- The control of oxidative phosphorylation in the adrenal gland (Y1) cell line / James E.J. Murphy and Richard K. Porter -- Replication of murine mitochondrial DNA following irradiation / Hengshan Zhang ... [et al.] -- Effects of anesthesia on brain mitochondrial function, blood flow, ionic and electrical activity monitored in vivo / Nava Dekel ... [et al.] -- The influence of flow redistribution on working rat muscle oxygenation / Louis Hoofd and Hans Degens -- Heterogeneity of capillary spacing in the hypertrophied plantaris muscle from young-adult and old rats / Hans Degens, Christopher I. Morse, and Maria T.E. Hopman -- Microvascularity of the lumbar erector spinae muscle during sustained prone trunk extension test / Rammohan V. Maikala and Yagesh N. Bhambhani -- Fiber capillary supply related to fiber size and oxidative capacity in human and rat skeletal muscle / Rob C.I. Wüst, Sarah L. Gibbings, and Hans Degens -- Novel therapeutic approach targeting the HIF-HRE system in the kidney / Masaomi Nangaku -- Carotid body sensory discharge and glomus cell HIF-1[alpha] are regulated by a common oxygen sensor / S. Lahiri ... [et al.] -- Impact of reactive oxygen species on the expression of adhesion molecules in vivo / Oliver Thews ... [et al.] -- Mini sensing chip for point-of-care acute myocardial infarction diagnosis utilizing micro-electro-mechanical system and nano-technology / Jianting Wang ... [et al.] -- A chemical biosynthesis design for an antiatherosclerosis drug by acyclic tocopherol intermediate analogue based on "isoprenomics" / Yoshihiro Uto ... [et al.] -- Zymogen protein C concentrate for safer heterozygote surgery, "I am a guinea pig!" / Duane F. Bruley -- Steady state redox levels in cytochrome oxidase : relevance for in vivo near infrared spectroscopy (NIRS) / Chris E. Cooper ... [et al.] -- Bicuculline-induced seizures : a challenge for optical and biochemical modeling of the cytochrome oxidase CUa NIRS signal / Chris E. Cooper ... [et al.] -- A method to calculate arterial and venous saturation from near infrared spectroscopy (NIRS) / Jan Menssen ... [et al.] -- Development of a dynamic test phantom for optical topography / Peck H. Koh, Clare E. Elwell, and David T. Delpy -- Numerical simulation of oxygen transport in cerebral tissue / Toshihiro Kondo ... [et al.] -- Non-invasive estimation of metabolic flux and blood flow in working muscle : effect of blood-tissue distribution / Nicola Lai ... [et al.] -- Oxygen extraction index measured by near infrared spectroscopy : a parameter for monitoring tissue oxygenation? / Oskar Baenziger ... [et al.] -- Non-invasive measurement of the superficial cortical oxygen partial pressure / Chris Woertgen ... [et al.] -- One sensor fits all : a new approach in monitoring brain physiology / H. Doll ... [et al.] -- Evaluation of NIRS data based on theoretical analysis of oxygen transport to cerebral tissue / Kazunori Oyama ... [et al.] -- Myocardial capillary net and blood constituents in streptozotocin (STZ-)-induced diabetic rats / Tomiyasu Koyama and Akira Taka -- Effects of proinsulin C-peptide on oxygen transport uptake and utilization in insulinopenic diabetic subjects : a review / Lina Nordquist and Sara Stridh -- Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging / Jenny Edlund ... [et al.] -- Identification and distribution of uncoupling protein isoforms in the normal and diabetic rat kidney / Malou Friederich ... [et al.] -- Iodinated contrast media decrease renomedullary blood flow : a possible cause of contrast media-induced nephropathy / Per Liss ... [et al.] -- C-peptide normalizes glomerular filtration rate in hyperfiltrating conscious diabetic rats / Sara Stridh ... [et al.] -- Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents / Jerry D. Glickson ... [et al.] -- Prognostic potential of the pre-therapeutic tumor oxygenation status / Peter Vaupel -- Histological basis of MR/optical imaging of human melanoma mouse xenografts spanning a range of metastatic potentials / He N. Xu ... [et al.] -- The relationship between vascular oxygen distribution and tissue oxygenation / Alexandru Daşu and Iuliana Toma-Daşu -- Intraoperative measurement of colonic oxygenation during bowel resection / Daya B. Singh ... [et al.] -- Quantifying tumour hypoxia by PET imaging : a theoretical analysis / Iuliana Toma-Daşu, Alexandru Da̧su, and Anders Brahme -- New measurements for assessment of impaired cerebral autoregulation using near-infrared spectroscopy / Dominique De Smet ... [et al.] -- Single shot T₁p magnetic resonance imaging of metabolically generated water in vivo / Eric A. Mellon ... [et al.] -- Brain tissue oxygen consumption and supply induced by neural activation : determined under suppressed hemodynamic response conditions in the anesthetized rat cerebral cortex / Kazuto Masamoto ... [et al.] -- Brain oxygen balance under various experimental pathophysiological conditions / Michal Schechter, Judith Sonn, and Avraham Mayevsky -- Ketones suppress brain glucose consumption / Joseph C. LaManna ... [et al.] -- False positives in functional near-infrared topography / Ilias Tachtsidis ... [et al.] -- Relationship between brain tissue haemodynamics, oxygenation, and metabolism in the healthy human adult brain during hyperoxia and hypercapnea / Ilias Tachtsidis ... [et al.] -- Use of a Codman microsensor intracranial pressure probe : effects on near infrared spectroscopy measurements and cerebral hemodynamics in rats / Helga Blockx, Willem Flameng, and Geofrey De Visscher -- Effect of severe hypoxia on prefrontal cortex and muscle oxygenation responses at rest and during exhaustive exercise / Thomas Rupp and Stéphane Perrey.
  • Part 1. Physiology and pathophysiology of O2 transport -- Part 2. In vivo measurement of O2 -- Part 3. Exercise and O2 transport -- Part 4. O2 microenvironment in cancer -- Part 5. Clinical aspects of O2 transport.
  • Mitochondrial genetic abnormalities after radiation exposure -- Crediting six discoverers of oxygen -- Hypoxia in tumors: pathogenesis-related classifi cation, characterization of hypoxia subtypes, and associated biological and clinical implications -- Heterogeneity in tissue oxygenation: from physiological variability in normal tissues to pathophysiological chaos in malignant tumours -- Oxygen diffusion: an enzyme-controlled variable parameter -- Role of microvascular shunts in the loss of cerebral blood flow autoregulation -- Impact of hypoxia-related tumor acidosis on cytotoxicity of different chemotherapeutic drugs in vitro and in vivo -- The founding of ISOTT: the Shamattawa of engineering science and medical science -- A tale of two methods: combining near- infrared spectroscopy with MRI for studies of brain oxygenation and metabolism -- Advances in probes and methods for clinical EPR oximetry -- Real-time, in vivo determination of dynamic changes In lung and heart tissue oxygenation using EPR oximetry -- Modulation of hypoxia by magnetic nanoparticle hyperthermia to augment therapeutic index -- Skeletal muscle and glioma oxygenation by carbogen inhalation in rats: a longitudinal study by EPR oximetry using single-probe implantable oxygen sensors -- Recurrent low-dose chemotherapy to inhibit and oxygenate head and neck tumors -- How in vivo EPR measures and images oxygen -- What we learn from in vivo EPR oxygen images -- EPR image based oxygen movies for transient hypoxia -- Repetitive measurements of intrarenal oxygenation in vivo using L band electron paramagnetic resonance -- Quantitative hypoxia imaging for treatment planning of radiotherapy -- A new flavonoid regulates angiogenesis and reactive oxygen species production -- Angiotensin II reduces transport-dependent oxygen consumption but increases transport-independent oxygen consumption in immortalized mouse proximal tubular cells -- Investigation of cerebral autoregulation In the newborn piglet during anaesthesia and surgery -- Influence of the maternal use of labetalol on the neurogenic mechanism for cerebral autoregulation assessed by means of NIRS -- Development of a near infrared multi- wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue haemodynamics and metabolism --Simulating NIRS and MRS measurements during cerebral hypoxia-ischaemia in piglets using a computational model -- Analysis of slow wave oscillations in cerebral haemodynamics and metabolism following subarachnoid haemorrhage -- Effects of enriched environment on hippocampal neuronal cell death and neurogenesis in rat global ischemia -- Automated image analysis for diameters and branching points of cerebral penetrating arteries and veins captured with two-photon microscopy -- Cerebral hemodynamic change and metabolic alteration in severe hemorrhagic shock -- Physiological mechanism of increase In deoxy-hemoglobin concentration during neuronal activation in patients with cerebral ischemia: a simulation study with the balloon model -- Effect of blood in the cerebrospinal fluid on the accuracy of cerebral oxygenation measured by near infrared spectroscopy -- Vessel specifi c imaging of glucose transfer with fluorescent glucose analogue in anesthetized mouse cortex -- Ischemic pretreatment delays ischemic brain vasospasm Injury in gerbils -- Changes in cerebral blood oxygenation induced by active standing test in children with POTS and NMS -- Optical imaging of brain activation in Gambian infants -- Asymmetrical changes in cerebral blood oxygenation induced by an active standing test in children with postural tachycardia syndrome -- Changes of cerebral tissue oxygen saturation at sleep transitions in adolescents -- Influence of subjective happiness on the prefrontal brain activity: an fNIRS study -- Ginkobiloba extract improves working memory performance in middle-aged women: role of asymmetry of prefrontal cortex activity during a working memory task -- Bayesian prediction of anxiety level in aged people at rest using 2-channel NIRS data from prefrontal cortex -- Short-term hypoxic preconditioning improved survival following cardiac arrest and resuscitation in rats -- Venular valves and retrograde perfusion -- Monitoring of filter patency during carotid artery stenting using near-infrared spectroscopy with high time-resolution -- Use of NIRS to assess effect of training on peripheral muscle oxygenation changes in elite rugby players performing repeated supramaximal cycling tests -- Skeletal muscle deoxygenation responses during treadmill exercise in children -- Development of a hybrid microwave-optical thermoregulation monitor for the muscle -- Evaluation of a textile-based near infrared spectroscopy system in calf muscle oxygenation measurements -- Skin temperature in lower hind limb subjected to distal vein arterialization in rats.
  • This text introduces students to clinical medicine by reviewing the pathophysiologic basis of the signs and symptoms of 100 diseases commonly encountered in medical practice. Each chapter first describes normal function of a major organ or organ system, then turns attention to the pathology and disordered physiology, including the role of genetics, immunology, and infection in pathogenesis. Underlying disease mechanisms are described, along with their systems, signs, and symptoms, and the way these mechanisms themselves determine the most effective treatment.
  • Ch. 1. History of physical activity contributions to public health / Amanda E. Paluch ... [et al.] -- Ch. 2. Physiological adaptations to moderate-intensity aerobic exercise / Arthur S. Leon and Scott Brown -- Ch. 3. The unique influence of sedentary behavior on health / Genevieve N. Healy -- Ch. 4. Physical activity in chronic disease prevention / Jared P. Reis and Bethany Barone Gibbs -- Ch. 5. Physical activity and injury prevention / Kenneth E. Powell -- Ch. 6. Physical activity in treatment of chronic conditions / J. Larry Durstine, Keith Burns, and Ryan Cheek -- Ch. 7. Physical activity in growth and development / Fátima Baptista and Kathleen F. Janz -- Ch. 8. Physical activity and healthy adulthood / Kelley K. Pettee Gabriel and Jennifer L. Gay -- Ch. 9. Physical activity and healthy aging / David M. Buchner -- Ch. 10. Physical activity and obesity / Catrine Tudor-Locke -- Ch. 11. Physical activity measurement / Stephen D. Herrmann -- Ch. 12. National guidelines for physical activity / Richard P. Troiano and David M. Buchner -- Ch. 13. Surveillance of physical activity / Janet E. Fulton and Susan A. Carlson -- Ch. 14. Physical activity promotion in underserved communities / Deborah Parra-Medina and Zenong Yin -- Ch. 15. Built environmental supports for walking / Paula Hooper ... [et al.] -- Ch. 16. Physical activity promotion in worksites / Joan Dorn and Cassandra Hoebbel -- Ch. 17. Promotion of physical activity in schools / Dianne Stanton Ward and Christopher Ford -- Ch. 18. Policy for physical activity promotion / Kelly R. Evenson and Semra A. Aytur
  • The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.
  • Fulltext ClinicalKey
    The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn's disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. Physiology of the Gastrointestinal Tract, 5/e covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. Discusses the multiple processes governing gastrointestinal functionEach section edited by preeminent scientist in the fieldUpdated, four-color illustrations.
  • Clear, consistent, and user-friendly, the updated edition of Physiology, by renowned physiology instructor Dr. Linda Costanzo, offers a comprehensive overview of core physiologic concepts at the organ system and cellular levels. It presents information in a short, simple, and focused manner, making it an ideal combination textbook and review guide for the USMLE Step 1. You'll grasp all the essential and relevant physiology knowledge you need for absolute success in school and on your exams! Build a strong understanding of the underlying principles of cellular physiology, the autonomic nervous system, and neurophysiology, as well as the cardiovascular, respiratory, renal, acid-base, gastrointestinal, endocrine, and reproductive organ systems.\Grasp physiology principles with absolute clarity through step-by-step explanations, easy-to-follow diagrams, and a full-color design, in addition to physiology equations and sample problems integrated throughout the text. Effortlessly study important points and reinforce your understanding of physiology with the help of chapter summaries and review questions. Access the entire contents online at Student Consult, including an image bank, 8 animations, "Ask the Author" section, and FAQs.
  • Phytoestrogens and health 2002, CRCnetBASE
    Generic Comments on Isoflavones and Other Phytoestrogens -- Chapter 1. Brief Historical Overview of Isoflavone Research / Mark Messina -- Chapter 2. Soy Isoflavones as Functional Ingredients in Women's Health / Clare M. Hasler and Susan Kundrat -- Chapter 3. Isoflavone Supplements: Arguments For and Against Their Use / Mark Messina -- Chapter 4. Industrial Processing and Preparation of Isoflavones / Eric T Gugger -- Food Sources and Composition of Phytoestrogens -- Chapter 5. Human Dietary Sources of Phytoestrogens and Methods of Determination / Chung-Ja C. Jackson and H.P. Vasantha Rupasinghe -- Chapter 6. Tables of Isoflavone, Coumestan, and Lignan Data / Chung-Ja C. Jackson and G. Sarwar Gilani -- Measurement Methodology of Phytoestrogens in Blood and Tissues -- Chapter 7. Analysis of Phytoestrogens in Biological Samples by Mass Spectrometry / Jeevan K. Prasain, Chao-Cheng Wang, and Stephen Barnes -- Chapter 8. Measurement Methodology for Phytoestrogens in Blood and Urine / Mariko Uehara -- Chapter 9. Metabolism and Disposition of Genistein, the Principal Soy Isoflavone / Daniel R. Doerge, Richard H. Luecke, and John F Young -- Digestion, Absorption and Metabolism of Isoflavones -- Chapter 10. Digestion, Absorption and Metabolism of Isoflavones / Roger A. King -- Cellular Mechanism of Action, Including Estrogen Receptors -- Chapter 11. Cellular Mechanisms of Action Including Estrogen Receptors: ER[alpha] and [beta] / Sari Mäkelä and Jan-Åke Gustafsson -- Chapter 12. Effects of Phytoestrogens on Bone Cells: Genomic and Nongenomic Mechanisms / Xiaowei Chen and John J.B. Anderson -- Cardiovascular Effects -- Chapter 13. Epidemiology of Soy Isoflavones and Cardiovascular Disease / M.Z. Vitolins, M.S. Anthony, and G.L. Burke -- Chapter 14. Soy/Isoflavones and Risk Factors for Cardiovascular Disease / Mary S. Anthony -- Chapter 15. Soy Proteins, Isoflavones, Cardiovascular Risk Factors, and Chronic Disease / David J.A. Jenkins, Cyril WC. Kendall, and Augustine Marchie -- Chapter 16. Lipoprotein Effects of Soybean Phytoestrogens / Sandra R. Teixeira and John W Erdman, Jr. -- Chapter 17. Effects of Free (Aglycone) Phytoestrogens and Metabolites on Cardiovascular Functions and Cancer / Paul Nestel and Alan Husband -- Skeletal Effects -- Chapter 18. Association Between Soy and/or Isoflavones and Bone: Evidence from Epidemiologic Studies / Mary S. Anthony, John J.B. Anderson, and D. Lee Alekel -- Chapter 19. Skeletal Effects of Phytoestrogens in Humans: Bone Mineral Density and Bone Markers / John J.B. Anderson and D. Lee Alekel -- Chapter 20. Skeletal Effects of Phytoestrogens: Rodent Models: Diet / Bahram H. Arjmandi and Brenda J. Smith -- Cancer -- Chapter 21. Phytoestrogens and Cancer: Epidemiologic Evidence / Anna H. Wu -- Chapter 22. Flaxseed Lignans: Health Benefits, Bioavailability, and Safety / Lilian U. Thompson and Wendy E. Ward -- Chapter 23. Phytoestrogens, Estrogens and Risk of Colon Cancer / Maurice R. Bennink and Elizabeth A. Rondini -- Chapter 24. Phytoestrogen Actions in the Breast and Uterus / Charles E. Wood, Stephen Barnes, and J. Mark Cline -- Chapter 25. Induction of Apoptosis by Genistein: Potential Applications in Cancer Prevention and Treatment / Andreas I. Constantinou -- Renal Effects -- Chapter 26. Phytoestrogens: Diabetic Nephropathy / Tammy J. Stephenson and James W Anderson -- Premenopausal Hormone Effects -- Chapter 27. Hormonal Effects of Phytoestrogens in Premenopausal Women / Alison M. Duncan, William R. Phipps, and Mindy S. Kurzer -- Postmenopausal, Potential Alternative to Traditional HRT -- Chapter 28. Phytoestrogens: Effects on Menopausal Symptoms / Fabien S. Dalais -- Chapter 29. Use of Soy Isoflavones as an Alternative to Traditional Hormone Replacement Therapy / Mara Z. Vitolins, Mary S. Anthony, and Gregory L. Burke -- Safety and Potential Toxicity -- Chapter 30. Deleterious Effects of Genistein Follow Exposure During Critical Stages of Development / Retha R. Newbold, Wendy Jefferson, Elizabeth Padilla-Banks, and Bill Bullock -- Chapter 31. Evaluation of Phytoestrogen Safety and Toxicity in Rodent Models That Include Developmental Exposure / Barry Delclos -- Chapter 32. The Health Consequences of Soy Infant Formula, Soy Protein Isolate, and Isoflavones / Thomas M. Badger, Martin J.J. Ronis, Reza Hakkak, and Sohelia Korourian -- Chapter 33. Public Health Implications of Dietary Phytoestrogens / Joel Rotstein, and G. Sarwar Gilani.
  • Functional Organization of the Human Body and Control of the "Internal Environment" -- The Cell and Its Functions -- Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction -- Transport of Substances through the Cell Membranes -- Membrane Potentials and Action Potentials -- Contraction of Skeletal Muscle -- Excitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction Coupling -- Excitation and Contraction of Smooth Muscle -- Cardiac Muscle; The Heart as a Pump and Function of the Heart Valves -- Rhythmical Excitation of the Heart -- The Normal Electrocardiogram -- Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial Analysis -- Cardiac Arrhythmias and Their Electrocardiographic Interpretation -- Overview of the Circulation; Biophysics of Pressure, Flow, and Resistance -- Vascular Distensibility and Functions of the Arterial and Venous Systems -- The Microcirculation and Lymphatic System: Capillary Fluid Exchange, Interstitial Fluid, and Lymph Flow -- Local and Humoral Control of Tissue Blood Flow -- Nervous Regulation of the Circulation, and Rapid Control of Arterial Pressure -- Role of the Kidneys in Long-Term Control of Arterial Pressure and in Hypertension: The Integrated System for Arterial Pressure Regulation -- Cardiac Output, Venous Return, and Their Regulation -- Muscle Blood Flow and Cardiac Output During Exercise; the Coronary Circulation and Ischemic Heart Disease -- Cardiac Failure -- Heart Valves and Heart Sounds; Valvular and Congenital Heart Defects -- Circulatory Shock and Its Treatment -- The Body Fluid Compartments: Extracellular and Intracellular Fluids; Edema -- Urine Formation by the Kidneys: I. Glomerular Filtration, Renal Blood Flow, and Their Control -- Urine Formation by the Kidneys: II. Tubular Reabsorption and Secretion -- Urine Concentration and Dilution; Regulation of Extracellular Fluid Osmolarity and Sodium Concentration -- Renal Regulation of Potassium, Calcium, Phosphate, and Magnesium; Integration of Renal Mechanisms for Control of Blood Volume and Extracellular Fluid Volume -- Acid-Base Regulation -- Diuretics, Kidney Diseases -- Red Blood Cells, Anemia, and Polycythemia -- Resistance of the Body to Infection: I. Leukocytes, Granulocytes, the Monocyte-Macrophage System, and Inflammation -- Resistance of the Body to Infection: II. Immunity and Allergy Innate Immunity -- Blood Types; Transfusion; Tissue and Organ Transplantation -- Hemostasis and Blood Coagulation -- Pulmonary Ventilation -- Pulmonary Circulation, Pulmonary Edema, Pleural Fluid -- Physical Principles of Gas Exchange; Diffusion of Oxygen and Carbon Dioxide through the Respiratory Membrane -- Transport of Oxygen and Carbon Dioxide in Blood and Tissue Fluids -- Regulation of Respiration -- Respiratory Insufficiency-Pathophysiology, Diagnosis, Oxygen Therapy -- Aviation, High-Altitude, and Space Physiology -- Physiology of Deep-Sea Diving and Other Hyperbaric Conditions -- Organization of the Nervous System, Basic Functions of Synapses, and Neurotransmitters -- Sensory Receptors, Neuronal Circuits for Processing Information -- Somatic Sensations: I. General Organization, the Tactile and Position Senses -- Somatic Sensations: II. Pain, Headache, and Thermal Sensations -- The Eye: I. Optics of Vision -- The Eye: II. Receptor and Neural Function of the Retina -- The Eye: III. Central Neurophysiology of Vision -- The Sense of Hearing -- The Chemical Senses-Taste and Smell -- Motor Functions of the Spinal Cord; the Cord Reflexes -- Cortical and Brain Stem Control of Motor Function -- Contributions of the Cerebellum and Basal Ganglia to Overall Motor Control -- Cerebral Cortex, Intellectual Functions of the Brain, Learning, and Memory -- Behavioral and Motivational Mechanisms of the Brain-The Limbic System and the Hypothalamus -- States of Brain Activity-Sleep, Brain Waves, Epilepsy, Psychoses -- The Autonomic Nervous System and the Adrenal Medulla -- Cerebral Blood Flow, Cerebrospinal Fluid, and Brain Metabolism -- General Principles of Gastrointestinal Function-Motility, Nervous Control, and Blood Circulation -- Propulsion and Mixing of Food in the Alimentary Tract -- Secretory Functions of the Alimentary Tract -- Digestion and Absorption in the Gastrointestinal Tract -- Physiology of Gastrointestinal Disorders -- Metabolism of Carbohydrates, and Formation of Adenosine Triphosphate -- Lipid Metabolism -- Protein Metabolism -- The Liver as an Organ -- Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals -- Energetics and Metabolic Rate -- Body Temperature Regulation, and Fever -- Introduction to Endocrinology -- Pituitary Hormones and Their Control by the Hypothalamus -- Thyroid Metabolic Hormones -- Adrenocortical Hormones -- Insulin, Glucagon, and Diabetes Mellitus -- Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth -- Reproductive and Hormonal Functions of the Male (and Function of the Pineal Gland) -- Female Physiology Before Pregnancy and Female Hormones -- Pregnancy and Lactation -- Fetal and Neonatal Physiology -- Sports Physiology.
  • Introduction to informatics / Liron Pantanowitz -- Basic computing / Seung L. Park, Anil V. Parwani, and Liron Pantanowitz -- Networking / Muhammad A. Syed, Anil V. Parwani, and Liron Pantanowitz -- Databases / Seung L. Park, Anil V. Parwani, and Liron Pantanowitz -- Coding / Seung L. Park, Jacqueline Cuda, and Liron Pantanowitz -- Laboratory information systems / Ioan C. Cucoranu, Anil V. Parwani, and Liron Pantanowitz -- Laboratory information system operations and regulations / Ioan C. Cucoranu, Anil V. Parwani, and Liron Pantanowitz -- Reporting / Liron Pantanowitz -- Quality management / Liron Pantanowitz, Luke T. Wiehagen, and R. Marshall Austin -- Barcoding / Ioan C. Cucoranu, Anil V. Parwani, and Liron Pantanowitz -- Informatics projects / Liron Pantanowitz -- Lean Six Sigman / Ioan C. Cucoranu, Anil V. Parwani, and Liron Pantanowitz -- Electronic medical records / Seung L. Park, Anil V. Parwani, and Liron Pantanowitz -- Digital imaging / Milon Amin, Anil V. Parwani, and Liron Pantanowitz -- Automated pap tests / Liron Pantanowitz -- Telecytology / Sara E. Monaco and Liron Pantanowitz -- Cytology online / Walid E. Khalbuss -- Bioinformatics / Somak Roy, Liron Pantanowitz, and Anil V. Parwani -- Research informatics / Somak Roy, Liron Pantanowitz, Anil V. Parwani.
  • Introduction : tumor classification and biologic potential / Jason L. Hornick -- Grading and reporting of soft tissue sarcomas / Jason L. Hornick -- Spindle cell tumors / Adrian Marino-Enriquez, Louis Guillou, and Jason L. Hornick -- Pediatric spindle cell tumors / Cheryl M. Coffin -- Tumors with myxoid stroma / Alessandra F. Nascimento and Jason L. Hornick -- Epithelioid and epithelial-like tumors / Essia Saiji, Louis Guillou, and Jason L. Hornick -- Pleomorphic sarcomas / J. Frans Graadt Van Roggen and Pancras C.W. Hogendoorn -- Round cell tumors / Enrique De Alava -- Biphasic tumors and tumors with mixed patterns / Alessandra F. Nascimento and Jason L. Hornick -- Tumors associated with prominent inflammatory cells / Jason L. Hornick -- Giant cell-rich tumors / Bernadette Liegl-Atzwanger and Jason L. Hornick -- Adipocytic tumors / Licia Laurino and Angelo Paolo Dei Tos -- Vascular tumors / Briana C. Gleason and Jason L. Hornick -- Cartilaginous and osseous soft tissue tumors / Andre M. Oliveira -- Cutaneous mesenchymal tumors / Thomas Brenn and Jason L. Hornick -- Mesenchymal tumors of the gastrointestinal tract / Brian P. Rubin and Jason L. Hornick -- Lower genital soft tissue tumors / Marisa R. Nucci -- Applications of molecular testing to differential diagnosis / Alexander J. Lazar.
  • Take the mystery out of MRI interpretation and its relationship to arthroscopy with this book by Drs. Mark D. Miller and Timothy G. Sanders. Abundantly illustrated with MR, arthroscopic, and anatomical images, this new title offers both orthopaedists and radiologists a correlated, systematic approach to diagnosis, helping you achieve accurate evaluations and ensuring that all clinically relevant structures are adequately assessed. An accompanying case-based DVD illustrates pathology and repair, with side-by-side comparisons of MRI and arthroscopic findings in the same patient. Improve diagnostic accuracy, surgical planning/decision making, and patient outcomes by seeing how to correlate MRI and arthroscopic findings. Gain an enhanced appreciation of the sensitivity and specificity of MRI as a tool in musculoskeletal diagnosis. Enhance your diagnostic skills by reviewing illustrative case studies for each major joint, examining specific MRI and arthroscopic findings and considering the range of possible diagnoses. View side-by-side comparisons of MRI and arthroscopic footage in the same patient - augmented by line illustrations that orient the arthroscopic views - by watching the videos on the bound-in DVD. Take the mystery out of MRI interpretation to assess more confidently.
  • v. 1.-- Part. I. Basic principles -- v. 2.-- Part. II. Molecular mechanisims of metabolic bone diseases -- Part. III. Pharmacological mechanisms of therapeutics -- Part. IV. Methods in bone research.
  • Fulltext ClinicalKey
    Chapter 1. The Effects of Gender in Neonatal Medicine / Tove S. Rosen, David Bateman -- Chapter 2. Sexual Development, Growth, and Puberty in Children / Gaya S. Aranoff, Jennifer J. Bell -- Chapter 3. Gender Differences in Pediatric Pulmonary Disease / Beverley J. Sheares -- Chapter 4. Gender-Specific Aspects of Pediatric Hematology and Oncology / James H. Garvin Jr. -- Chapter 5. Gender Differences in Neurological Conditions of Children / David M. Kaufman -- Chapter 6. Gender and Sports: Past, Present, and Future / Jordan D. Metzl -- Chapter 7. Gender Differences in the Functional Organization of the Brain / Ruben C. Gur, Tamara Bockow, Raquel E. Gur -- Chapter 8. Sexual Differentiation of Brain Structure and Function / Margaret M. McCarthy -- Chapter 9. The Sexed and Gendered Brain / William Byne -- Chapter 10. Age and Gender-Specific Patterns of Neurologic Illness / Joan Amatniek, Karin Sorra, Lauren Frey, W. Allen Hauser -- Chapter 11. Gender Differences in Stroke / Rebecca F. Gottesman, Argye E. Hillis -- Chapter 12. Gender Differences in Disorders that Present to Psychiatry / Mary V. Seeman -- Chapter 13. Hormone Replacement Therapy and Cognitive Function / Mary Sano, Diane Jacobs, Katya Gaynor -- Chapter 14. Gender and the Heart: Sex-Specific Differences in the Normal Myocardial Anatomy and Physiology / Marianne J. Legato, Jaswinder K. Leghe -- Chapter 15. Gender-Specific Aspects of Selected Coronary Heart Disease Risk Factors: A Summary of the Epidemiologic Evidence / Shari S. Bassuk, JoAnn E. Manson -- Chapter 16. Dyslipidemia Management in Women and Men: Exploring Potential Gender Differences / Kavita Sharma, Christian D. Nagy, Roger S. Blumenthal -- Chapter 17. Gender Differences in the Role of Stress and Emotion in Cardiovascular Function and Disease / David E. Anderson, Margaret A. Chesney -- Chapter 18. The Role of Sex and Gender in Cardiothoracic Surgery / Sandhya K. Balaram, Justin D. Blasberg -- Chapter 19. Gender Differences in Asthma / Robert H. Lim, Lester Kobzik -- Chapter 20. Gender Issues in Venous Thromboembolism / Susan Murin, Kathryn Bilello, Lisa Moores, Aaron Holley -- Chapter 21. Sleep in Women: Gender Differences in Health and Disease / Shirin Shafazand -- Chapter 22. Are Women More Susceptible to Chronic Obstructive Pulmonary Disease? / Kenneth R. Chapman -- Chapter 23. The Gender-Specific Aspects of Lung Cancer / Rebecca L. Toonkel, Charles A. Powell -- Chapter 24. Gender-Specific Considerations in Pulmonary Hypertension / Deborah Shure -- Chapter 25. Sex and Gender Differences in Pulmonary Manifestations of Autoimmune Disease / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 26. Benign Metastasizing Leiomyoma and Lymphangioleiomyomatosis: Lung Diseases of Women / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 27. Gender Differences in Susceptibility, Outcomes, and Pathophysiology of Sepsis / Kristy A. Bauman, MeiLan K. Han -- Chapter 28. Inflammatory Bowel Disease in Women / Melissa Munsell, Marc Sonenshine, Mary L. Harris -- Chapter 29. Disorders of Defecation in Women / Susan L. Gearhart -- Chapter 30. Idiopathic Gastroparesis: Gender Aspects / Henry P. Parkman --Chapter 31. Liver Disease in Women / Karen Krok, Ayman Koteish -- Chapter 32. Gender Differences in Irritable Bowel Syndrome / Octavia Pickett-Blakely, Linda A. Lee, Gerald Mullin -- Chapter 33. Contraception / Karen Feisullin, Carolyn Westhoff -- Chapter 34. Infertility: The Male / Howard H. Kim, Peter N. Schlegel, Marc Goldstein -- Chapter 35. Infertility and In Vitro Fertilization / Elizabeth Barbieri, Sonya Kashyap, Pak H. Chung -- Chapter 36. Female Sexual Health / Barbara D. Bartlik, Julie A. Kolzet, Nazia Ahmad, Tahmina Parveen, Sarah Alvi -- Chapter 37. Male Sexual Dysfunction / Serkan Deveci, John P. Mulhall -- Chapter 38. Pelvic Pain: Urogenital Female Disorders / Andrew T. Goldstein, Lara J. Burrows -- Chapter 39. Lower Urogenital Tract Dysfunction in Men and Women / Doreen E. Chung, Alexis E. Te, Renuka Tyagi -- Chapter 40. Aging and the Lower Urogenital System / Catherine E. DuBeau -- Chapter 41. Menopause / Gloria Bachmann, Nora J. Doty -- Chapter 42. The Differences between Male and Female Breast Cancer / Coral Omene, Amy Tiersten -- Chapter 43. Difference in Germ Cell Tumors of the Reproductive Tract in Men and Women / Nicole LaNatra, Amy Tiersten -- Chapter 44. Gender Differences in Hereditary Cancer Syndromes: Risks, Management, and Testing for Inherited Predisposition to Cancer / Wendy K. Chung -- Chapter 45. Gender Differences in Emerging Infectious Diseases / Sharon Lewin -- Chapter 46. Sexually Transmitted Infections in Men and Women / Anne M. Rompalo, Khalil G. Ghanem -- Chapter 47. Infections in Pregnancy / Emilia Mia Sordillo, Bruce Polsky -- Chapter 48. Adult Immunization in Women and Men / Sally L. Hodder, Debra Chew, Shobha Swaminathan -- Chapter 49. Gender Differences in Autoimmune Diseases: Immune Mechanisms and Clinical Applications / Nabih I. Abdou, Virginia Rider -- Chapter 50. Hormones and Cytokines: Gender-Specific Effects / Maurizio Cutolo -- Chapter 51. Prolactin and Autoimmunity / Sara E. Walker -- Chapter 52. Sex Hormones and Immune Function / Robert G. Lahita -- Chapter 53. Pregnancy and Autoimmune Rheumatic Disease / Carl A. Laskin, Christine A. Clark, Karen A. Spitzer -- Chapter 54. Oral Contraceptives and Autoimmune Diseases / Taraneh Mehrani, Michelle Petri -- Chapter 55. Gender-Specific Issues in Organ Transplantation / Hilary Sanfey Chapter 56. Endogenous Sex Hormones and Risk of Type 2 Diabetes Mellitus in Men and Women / Sherita Hill Golden -- Chapter 57. Thyroid Disorders and Pregnancy / Matthew Kim -- Chapter 58. Sexual Function and Dysfunction in Men and Women / Karen Elizabeth Boyle, Arthur L. Burnett -- Chapter 59. Osteoporosis in Men and Women / Kendall F. Moseley, Suzanne M. Jan de Beur -- Chapter 60. Testosterone Replacement Therapy in Men and Women / Diala El-Maouche, Adrian Dobs.
  • Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer's disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume covers history from the high Middle Ages to the TSE era of Daniel Carleton Gajdusek, followed by the prion era of Stanley Prusiner whose extraordinary discovery opened a new chapter in prion research. Volume I will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.
  • Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.
  • Neural anatomy -- Passive membranes -- Active membranes -- Propagation -- Neural branches -- Synapses -- Networks of neurons -- Extracellular recording and stimulation -- The neural code -- Applications.
  • Get the most from your study time, and experience a realistic USMLE simulation, 2nd Edition, by Dr. Thomas A. Brown. This new reference in the highly rated Rapid Review Series is formatted as a bulleted outline with clinical images, tables and figures that make it easy to review all the physiology information you need to know for the USMLE. And with Student Consult online access, you can become familiar with the look and feel of the actual exam by taking a timed or a practice online test that includes 350 USMLE-style questions. Review the most current information with completely updated chapters, images, and questions. Profit from the guidance of series editor Dr. Edward Goljan, a well-known author of medical review books, who reviewed and edited every question. Study and take notes more easily with the new, larger page size. This edition thoroughly updated, including student and resident reviewer feedback to ensure relevancy and focus. Practice with a new testing platform on the USMLE Consult testing engine that gives you a realistic review experience and fully prepares you for the exam.
  • "Resistance training is a form of strength training in which each effort is performed against a specific, opposing force generated by resistance. Increasing evidence-based research highlights the importance of not only aerobic exercise, but resistance training in the prevention, management, and treatment of many chronic conditions. This book presents research on the benefits of resistance training for chronic diseases/disorders. Chapters cover resistance training to treat cardiovascular disease, metabolic diseases, cancer, orthopedic diseases, and neuromuscular disorders"--Provided by publisher.
  • Respiratory Muscle Training: theory and practice is the world's first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts - theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge - and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (, which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via, which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. Introductory overviews of respiratory and exercise physiology, as well as training theory Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation Evidence-based guidance on the implementation of inspiratory muscle resistance training Over 150 functional exercises that incorporate a breathing challenge - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec's RMT exercise module (via
  • Review of medical physiology 2012 (24th ed.), AccessMedicine
  • The sarcomere and sarcomerogenesis / Elisabeth Ehler and Mathias Gautel -- Skeletal muscle alpha-actin diseases / Kathryn N. North and Nigel G. Laing -- Nebulin : a giant chameleon / Katarina Pelin and Carina Wallgren-Pettersson -- Skeletal muscle disease due to mutations in tropomyosin, troponin, and cofilin / Nigel F. Clarke -- Investigations into the pathobiology of thin-filament myopathies / Biljana Ilkovski -- Mouse models for thin filament disease / Mai-Anh T. Nguyen and Edna C. Hardeman -- Thick filament diseases / Anders Oldfors and Phillipa J. Lamont -- Acute quadriplegic myopathy : an acquired "myosinopathy" / Lars Larsson -- Third filament diseases / Bjarne Udd -- The Z-disk diseases / Duygu Selcen and Olli Carpén -- Intermediate filament diseases : desminopathy / Lev G. Goldfarb ... [et al.] -- Muscular integrity : a matter of interlinking distinct structures via plectin / Patryk Konieczny and Gerhard Wiche -- The sarcomere and the nucleus : functional links to hypertrophy, atrophy, and sarcopenia / Mathias Gautel -- Other model organisms for sarcomeric muscle diseases / John Sparrow, Simon M. Hughes, and Laurent Segalat -- Therapeutic approaches for the sarcomeric protein diseases / Kristen J. Nowak.
  • Overview of Sarcopenia -- Muscle wasting in cancer and ageing: cachexia versus sarcopenia -- Age-related remodeling of neuromuscular junctions -- Aging related changes motor unit structure and function -- Excitation-contraction coupling regulation in aging skeletal muscle -- Alterations in mitochondria and their impact in aging skeletal muscle -- Skeletal muscle collagen: age, injury and disease -- Nuclear apoptosis and sarcopenia -- Age-related changes in the molecular regulation of skeletal muscle mass -- Genetic variation and skeletal muscle traits: implications for sarcopenia -- Proteomic and biochemical profiling of aged skeletal muscle -- Exercise and nutritional interventions to combat age-related muscle loss -- Reactive oxygen species generation and skeletal muscle wasting, implications for sarcopenia -- Exercise as a countermeasure for sarcopenia -- Role of contraction-induced injury in age-related muscle wasting and weakness -- Role of IGF-1 in age-related loss of skeletal muscle mass and function -- Role of myostatin in skeletal muscle growth and development: implications for sarcopenia -- Role of beta-adrenergic signalling in skeletal muscle wasting: implications for sarcopenia -- Index.
  • Sobotta - Atlas of Human Anatomy: the exam atlas for understanding, learning, and training anatomy The English-language Sobotta Atlas with English nomenclature is specifically adapted to the needs of preclinical medical students. Right from the start, the book and the Internet content concentrate on exam-relevant knowledge. The new study concept simplifies learning-understanding-training: Descriptive legends help the student identify the most important features in the figures. Clinical examples present anatomical details in a wider context. All illustrations have been optimized, and the lettering reduced to a minimum. An additional booklet containing 100 tables on muscles and nerves supports systematic study. Volume 1 "General Anatomy and Musculoskeletal System" includes the following topics: General Anatomy Trunk Upper Extremity Lower Extremity.
  • "Human growth refers to changes in anthropometric measurements, such as fetal size parameters, height, weight, and body mass index. Development refers to changes in cognitive, social-emotional, locomotor, and other abilities. This book illustrates how statistical methods can be used to answer research questions in human growth and development. In addition to describing methods, it looks at how well a method addresses a specific research question and how to interpret and present the analytic results. Although the examples are drawn from human growth and development, the concepts and methods are applicable to studies of many other physical and psychological phenomena, such as lung function and depressive symptoms. Requiring introductory statistics knowledge, the book is intended for clinical researchers, epidemiologists, social scientists, statisticians, related researchers, and post-graduate students investigating human growth and development"--Provided by publisher.
  • This book adopts an interdisciplinary approach in seeking to identify the impact of living conditions in space on the adaptation of the immune system.
  • Chapter 1. Lipid structure -- Chapter 2. The mesomorphic phase behavior of lipid bilayers -- Chapter 3. Lipid bilayer interdigitation -- Chapter 4. The dynamics of membrane lipids -- Chapter 5. Nonlamellar lipid phases -- Chapter 6. The forces between interacting bilayer membranes and the hydration of phospholipid assemblies -- Chapter 7. The roles of cholesterol in the biology of cells -- Chapter 8. Lipid membrane fusion -- Chapter 9. Membrane rafts -- Chapter 10. Passive and facilitated transport -- Chapter 11. Membrane protein dynamics: rotational dynamics -- Chapter 12. Translational diffusion of membrane proteins -- Chapter 13. Inorganic anion transporter AE1 -- Chapter 14. The structures of G-protein coupled receptors -- Chapter 15. Role of membrane lipids in modulating the activity of membrane-bound enzymes -- Chapter 16. Viral fusion mechanisms.
  • A step-by-step learning text and atlas designed to teach essential and foundational skills of musculoskeletal physical assessment. Comprised of a 3-part learning system: 1. Screening Musculoskeletal Examination (SMSE): rapid assessment of structure and function 2. General Musculoskeletal Examination (GMSE): comprehensive assessment of joint inflammation and arthritis 3. Regional Musculoskeletal Examination (RMSE): focused assessments of structure and function combined with special testing of the shoulder, knee, and neck and low back.
  • Taurine. 6 2006, Springer
  • Taurine. 7 2009, Springer
  • Taurine. 8 v. 1-2, 2013., Springer
    v.2 Springer
    Volume 1. The Nervous system, immune system, diabetes and the cardiovascular system -- Volume 2. Nutrition and metabolism, protective role, and role in reproduction, development, and differientiation.
  • "Get the best results from the latest procedures with Tendon Surgery of the Hand , the only reference that offers comprehensive coverage of this complex and challenging area. World-renowned experts guide you through all of the newest techniques and technologies , equipping you to restore optimal function in your patients. It's your one-stop source for mastering today's best approaches to treating tendon injuries and disorders of the hand."--Publisher's website.
  • The evolutionary basis of thermoregulation and exercise performance / F.E. Marino -- Comparative thermoregulation and the quest for athletic supremacy / F.E. Marino -- Thermoregulation, fatigue, and exercise modality / R. Tucker -- Neuromuscular response to exercise heat stress / S.S. Cheung -- Intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms : the "canary in the coal mine" during exercise-heat stress? / G.P. Lambert -- Effects of peripheral cooling on characteristics of local muscle / E. Drinkwater -- Cooling interventions for the protection and recovery of exercise performance from exercise-induced heat stress / R. Duffield -- Ethnicity and temperature regulation / M.I. Lambert, T. Mann, J.P. Dugas -- Exercise heat stress and metabolism / T. Mündel.
  • Mammalian transglutaminases : a family portrait / Mehta, K. -- Structure-function relationships of transglutaminases, a contemporary view / Nemes, Z., Csosz, E., Fesus, L. -- Transglutaminases and their substrates / Facchiano, F., Facchiano, A. -- Type 2 transglutaminase and cell death / Piacentini, M. ... [et al.] -- Transglutaminase and cell-survival signaling / Singh, U.S., Pan, J. -- Transglutaminases in wound healing and inflammation / Verderio, E.A.M., Johnson, T.S., Griffin, M. -- Transglutaminases in epidermis / Eckert, R.L. ... [et al.] --Tissue transglutaminase (TG2) in cancer biology / Mangala, L.S., Mehta, K. -- Transglutaminases in neurodegenerative disorders / Bailey, C.D.C., Tucholski, J., Johnson, G.V.W. -- Tissue transglutaminase and celiac disease / Esposito, C. ... [et al.] -- Transglutaminases as biotechnological tools / Mariniello, L., Porta, R. -- Extracellular transglutaminase: factor XIII / Ichinose, A. -- Transglutaminases of lower organisms / Rao, R.U., Chandrashekar, R., Mehta, K. -- Transglutaminases of higher, lower plants and fungi / Del Duca, S., Serafini-Fracassini, D.
  • Muscle chains / Philipp Richter: introduction -- Models of myofascial chains -- Physiology -- The craniosacral model -- The biomechanical model of John Martin Littlejohn : the mechanics of the spinal column -- Postural muscles, phasic muscles, and crossed syndrome (Vladimir Janda's contribution to myofacial treatment methods) -- Zink patterns -- Myofascial chains : a model -- Posture -- Diagnosis -- Therapy -- Trigger points and their treatment / Eric hebgen: Definition -- Classification of trigger points -- Pathophysiology of trigger points -- Diagnosis -- Trigger point therapy -- Trigger point-sustaining factores -- The facilitated segment -- The trigger points.
  • What sustains life? an overview -- The pilgrimage: highlights in our understanding of products and components of living organisms -- Likelihood of life's protein machines: extravagant in construction yet efficient in function -- Consilient mechanisms for diverse protein-based machines: the efficient comprehensive hydrophobic effect -- On the evolution of protein-based machines: toward complexity of structure and diversity of function -- Biology thrives near a movable cusp of insolubility -- Consilient mechanisms for the protein-based machines of biology -- Advanced materials for the future: protein-based materials with potential to sustain individual health and societal development -- Appendix 1. Mechanics of elastin: molecular mechanism of biological elasticity and its relationship to contraction / Dan W. Urry and Timothy M. Parker -- Appendix 2. Development of elastic protein-based polymers as materials for acoustic absorption / Dan W. Urry... [et al.]
  • Wnt signaling 2008, Springer Protocols
    v. 1. Pathway methods and mammalian models -- v. 2. Pathway models.
all 198 titles

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Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides one-click access to important clinical resources; includes evidence-based diagnosis and treatment guidelines, Books, EBM articles, Ovid MEDLINE, Drug facts and comparisons, Drug interaction facts, guidelines from National Guideline Clearinghouse, patient handouts (English and Spanish), and local content.MD consult provides access to textbooks, electronic journals, practice guidelines, drug information, and patient education handouts.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.