Books by Subject

Physics

  • Digital
    Josef Flammer, Maneli Mozaffarieh, Hans Bebie.
    Digital : Springer2013
    What Is Light? -- The Interaction Between Light and Matter -- Light Sources -- Examinations with Light -- Ultrasound Diagnostics -- Further Imaging Procedures -- Interventions with Laser Light -- Some History of Chemistry -- Oxygen -- Water -- Carbon Dioxide (CO2) -- Nitric Oxide -- Redox Reactions -- DNA -- RNA -- Proteins -- Lipids -- Matter: Using Water as an Example -- If You Are Interested in More ... -- Appendix: Units and Constants.
  • Digital
    Magdy M. Khalil (ed.).
    Digital : Springer2011
    Basic physics and radiation safety in nuclear medicine -- Radiopharmacy: basics -- Technetium-99m radiopharmaceuticals -- Radiopharmaceutical quality control -- PET chemistry: an introduction -- PET chemistry: radiopharmaceuticals -- Radiation dosimetry: definitions and basic quantities -- Radiation dosimetry: formulations, models, and measurements -- Radiobiology: concepts and basic principles -- Elements of gamma camera and SPECT systems -- Positron emission tomography (PET): basic principles -- Fundamentals of image processing in nuclear medicine -- Emission tomography and image reconstruction -- Quantitative SPECT imaging -- Quantitative cardiac SPECT imaging -- Tracer kinetic modeling: basics and concepts -- Tracer kinetic modeling: methodology and applications -- Preclinical imaging.
  • Digital
    David Cubero, Ferruccio Renzoni.
    Digital : Cambridge2016
    Limitations imposed by the second law of thermodynamics -- Fundamental models of ratchet devices -- General relevance of the concept of ratchets -- Classical ratchets -- Quantum ratchets -- Energetics and characterization -- Ratchets for colloidal particles -- Cold atom ratchets -- Solid state ratchets -- Bio-inspired molecular motors
  • Digital
    Digital1998
  • Digital
    Lide, David R.; Weast, Robert C.
    Digital1978-latest ed. only
  • Digital
    edited by D.A. Christie and E.M. Tansey.
    Digital : Wellcome Trust2006
  • Digital
    edited by Dipak Basu.
    Digital : CRCnetBASE2001
  • Print
    Jonathan Orsay.
    Status: Not Checked OutLane Catalog Record
  • Digital
    edited by T.W.J. Gadella.
    Digital : ScienceDirect2009.
  • Digital
    Paul Suetens, KU Leuven, Belgium.
    Digital : Cambridge2017
    1. Introduction to digital image processing -- 2. Radiography -- 3. X-ray computed tomography -- 4. Magnetic resonance imaging -- 5. Nuclear medicine imaging -- 6. Ultrasound imaging -- 7. Medical image computing -- 8. Visualization for diagnosis and therapy.
  • Digital
    edited by G. Gauglitz and T. Vo-Dinh.
    Digital : Wiley2003
    v. 1. -- Part I. Sample preparation and sample pretreatment -- ch. 1. Collection and preparation of gaseous samples / Douglas A. Lane -- ch. 2. Sample collection and preparation of liquid and solids / Brian M. Cullum, Tuan Vo-Dinh -- Part II. Methods 1: Optical spectroscopy -- ch. 3. Basics of optical spectroscopy / Martin Hof -- ch. 4. Instrumentation / Valdas Sablinskas -- ch. 5. Measurement techniques / Gerald Steiner -- ch. 6. Applications / Valdas Sablinskas, Gerald Steiner, Martin Hof -- Part III. Methods 2: Nuclear magnetic resonance spectroscopy -- ch. 7. An Introduction to solution, solid-state, and imaging NMR spectroscopy / Leslie G. Butler -- ch. 8. Solution NMR spectroscopy / Gary E. Martin, Chad E. Hadden, David J. Russell -- ch. 9. Solid-state NMR / Steven P. Brown, Lyndon Emsley -- Part IV. Methods 3: Mass spectrometry -- ch. 10. Mass spectrometry / Michael Przybylski, Wolfgang Weinmann, Thilo A. Fligge -- Part V. Methods 4: Elemental analysis -- ch. 11. X-ray fluorescence analysis / K. Janssens -- ch. 12. Atomic absorption spectrometry (AAS) and atomic emission spectrometry (AES) / Erwin Rosenberg, Ulrich Panne -- Part VI. Methods 5: Surface analysis techniques -- ch. 13. Surface analysis techniques / A. Macková, S.A. Morton, C.G.H. Walker, K. Volka -- v. 2. -- Part VII. Applications 1: Bioanalysis -- ch. 14. Bioanalysis / Willem M. Albers, Arto Annila, Nicholas J. Goddard, Gabor Patonay, Erkki Soini -- Part VIII. Applications 2: Environmental analysis -- ch. 15. LC-MS in environmental analysis / H.Fr. Schröder -- ch. 16. Gas chromatography/ion trap mass spectrometry (GC/ITMS) for environmental analysis / Michel Sablier, Toshihiro Fujii -- Part IX. Application 3: Process control -- ch. 17. Optical spectroscopy / John Green -- ch. 18. NMR / Loring A. Weisenberger -- ch. 19. Process mass spectrometry / Christian Hassell -- ch. 20. Elemental analysis / J.S. Crighton -- Part X. Hyphenated techniques -- ch. 21. Hyphenated techniques for chromatographic detection / John C. Fetzer -- Part XI. General data treatment: data bases/spectral libraries -- ch. 22. Optical spectroscopy / Steffen Thiele, Reiner Salzer -- ch. 23. Nuclear magnetic resonance spectroscopy / Wolfgang Robien -- ch. 24. Mass spectrometry / Antony N. Davies.
  • Digital
    Todd Pawlicki, Daniel J. Scanderbeg, George Starkschall.
    Digital : Wiley2016
    Atomic structure and radioactive decay -- Interactions of X rays and gamma rays -- Interactions of particulate radiation with matter -- Machines for producting radiation -- Measurement of ionizing radiation -- Calibration of megavoltage beams of X rays and electrons -- Central-axis point dose calculations -- External beam dose calculations -- External beam treatment planning and delivery -- The basics of medical imaging -- Diagnostic imaging and applications to radiation therapy -- Tumor targeting: image-guided and adaptive radiation therapy -- Computer systems -- Radiation oncology informatics -- Physics of proton radiation therapy -- Sources for implant therapy and dose calculation -- Brachytherapy treatment planning -- Radiation protection -- Quality assurance -- Patient safety and quality improvement.
  • Digital
    Liang Liang.
    Digital2013
    Inhibition occurs throughout the nervous system and impacts diverse neuronal processes. In this dissertation, I focus on an inhibitory circuit motif in the Drosophila olfactory system, parallel inhibition, which differs from the classical feed-forward or feedback inhibition. The Drosophila excitatory and GABAergic inhibitory projection neurons (ePNs and iPNs) each receive input from antennal lobe glomeruli and send parallel output to the lateral horn, a higher-order brain center implicated in regulating innate olfactory behavior. By incorporating in vivo two-photon calcium imaging, advanced fly genetics and optogenetic methods to manipulate and record neuronal activity, we find that iPNs selectively suppress food-related odorant responses but spare signals from pheromone channel stimulation when using specific lateral horn neurons as an olfactory readout. Co-applying food odorant does not affect pheromone signal transmission, suggesting that the differential effects likely result from connection specificity of iPNs, rather than a generalized inhibitory tone. Calcium responses in the ePN axon terminals show no detectable suppression by iPNs, arguing against presynaptic inhibition as a primary mechanism. The parallel inhibition motif may provide specificity in inhibition to funnel specific olfactory information, such as food and pheromone, into distinct downstream circuits.
  • Digital
    Faiz M. Khan, John P. Gibbons.
    Digital : Ovid2014
    Structure of matter -- Nuclear transformations -- Production of x-rays -- Clinical radiation generators -- Interactions of ionizing radiation -- Measurement of ionizing radiation -- Quality of x-ray beams -- Measurement of absorbed dose -- Dose distribution and scatter analysis -- A system of dosimetric calculations -- Treatment planning i : isodose distributions -- Treatment planning ii : patient data acquisition, treatment verification, and -- Inhomogeneity corrections -- Treatment planning iii: field shaping, skin dose, and field separation -- Electron beam therapy -- Low-dose-rate brachytherapy: rules of implantation and dose specification -- Radiation protection -- Quality assurance -- Total body irradiation -- Three-dimensional conformal radiation therapy -- Intensity-modulated radiation therapy -- Stereotactic radiotherapy and radiosurgery -- Stereotactic body radiation therapy -- High-dose-rate brachytherapy -- Prostate implants: technique, dosimetry, and treatment planning -- Intravascular brachytherapy -- Image-guided radiation therapy -- Proton beam therapy.
  • Digital
    Christopher Koerner Sramek.
    Digital2010
    Since its introduction nearly 40 years ago, laser photocoagulation has been the standard of care for treatment of numerous retinal pathologies. Recently, new approaches have been introduced for more selective targeting of various retinal layers, including patterned scanning photocoagulation, selective retinal therapy, and sub-lethal treatment. Despite its broad use in clinical practice, there remains a need for the quantitative description of laser-tissue interactions involved in retinal phototherapy. A unified description of various treatment regimes and associated mechanisms of tissue damage would allow for optimization of laser parameters to improve selectivity and safety of retinal photocoagulation, and for avoidance of undesirable collateral damage. The presented work describes an investigation into the dynamics of the retinal response to hyperthermia and vaporization. A finite-element computational model of photocoagulation and rupture was constructed based on experimental measurements of laser interactions with tissue, and verified in vivo in the millisecond time domain. Two approaches towards improvement of tissue heating uniformity were studied: spatial and temporal modulation of the treatment beam. After optimization using the computational model, beam shaping and pulse modulation systems were constructed. Experimental studies in vivo confirmed improvements in safety of the retinal treatment, potentially allowing for reductions in treatment time, thermal damage extent, and perceived pain. In addition, tissue response to sub-lethal thermal stress in the retina was explored using expression of heat shock protein in an animal model. Computational modeling of the corresponding treatment regime demonstrated that a similar response is likely to occur in clinical application of sub-lethal exposures. Photo-mechanical interactions in the retina were investigated in model systems and in vivo with microsecond-range exposures. The dominant mechanisms of tissue damage were identified and the corresponding limits of the safe therapeutic window were computed over a broad range of pulse durations - from microseconds to seconds. An understanding of the thermal and mechanical interactions involved in laser heating of the retina allows for the realization of safer and more selective treatment regimes. All three mechanisms investigated in the current study -- photocoagulation, photomechanical interactions and sub-lethal hyperthermia -- play a role in clinical treatment. The developed quantitative models of these interactions have immediate applicability to clinical practice, providing guidance towards optimization of retinal phototherapy, evaluation of retinal safety, and development of new clinical applications.
  • Print
    edited by Alexander Stone Macnow, MD.
    Status: Not Checked OutLane Catalog Record
    Kinematics and Dynamics -- Work and Energy -- Thermodynamics -- Fluids -- Electrostatics and Magnetism -- Circuits -- Waves and Sound -- Light and Optics -- Atomic and Nuclear Phenomena -- Mathematics -- Reasoning About the Design and Execution of Research -- Data-Based and Statistical Reasoning.
  • Digital
    Aakash Basu.
    Digital2013
    DNA gyrase is a molecular motor that directionally introduces negative supercoils into DNA, serving a function that is critical to most bacterial life. This thesis addresses the question of how gyrase transduces chemical energy stored in ATP into mechanical energy stored in supercoiled DNA. I have investigated how substeps in the ATPase cycle -- ATP binding, hydrolysis and product release -- coordinate structural transitions of the nucleoprotein complex during the course of the supercoiling reaction. Using single-molecule real-time tracking of DNA compaction and rotation, I have characterized the geometry and interconversion dynamics of DNA configurations under different nucleotide conditions. A critical step in the reaction cycle of DNA gyrase involves the formation and manipulation of a chiral wrap in the path of DNA on a scale of ~ 150 base pairs. I show that chiral wrapping is a multistep process that dominates the overall kinetics and is modulated by ATP. My results identify new roles for ATP binding, hydrolysis and product release, and show that nucleotide states in gyrase cannot be uniquely identified with structural intermediates. The work reveals a sophisticated molecular motor in which a conformational landscape of loosely coupled transitions funnels the enzyme toward productive energy transduction.
  • Print
    Fred A. Mettler, Jr., Arthur C. Upton.
    Print2008
    Status: Not Checked OutLane Catalog Record
    Basic radiation physics, chemistry, and biology -- Sources of radiation exposure -- Effects on genetic material -- Cancer induction and dose-response models -- Carcinogenesis of specific sites -- Deterministic effects of radiation -- Effects of radiation in combination with other agents -- Radiation exposure in utero -- Uranium, plutonium, and radium -- Attribution of radiation effects and probability of causation in a specific individual -- Perception of radiation and psychological risks -- Hormesis.
  • Digital
    Aaron Michael Streets.
    Digital2012
    Phase transitions are ubiquitous in nature. Fundamental study of phase transition phenomena is a cornerstone of condensed matter physics, and theoretical results in this area guide technology development in material science. Phase transitions also play an important role in biology. Biological macromolecule phase transitions occur in many biological processes, for example the gel-liquid transition in lipid bilayers and amyloid formation in protein aggregation disease. From a technological standpoint, the ability to crystallize proteins has enabled one of the most important advances in biology of the last century: protein structure determination with X-ray crystallography. However, biological macromolecule phase transitions often display stark phenomenological differences from their inorganic analogs. This owes to the sheer size and complexity of proteins and nucleic acid complexes. Macromolecular phase transition theory is rich in subtleties, anecdotal & counter-intuitive results, and often diverges from predictions of classical theory. In addition to developing theory, fundamental study in this area is also critical for improvements in high-throughput crystallography efforts and in understanding mechanisms of devastating neurodegenerative diseases. This thesis approaches the study of macromolecule phase transitions through the development of new measurement technology. In this work, spectroscopic and imaging techniques are combined with microfluidic systems to provide insight into three areas of macromolecule phase transitions. First, dynamic light scattering and microscopy are integrated onto a microfluidic platform to study and optimize protein crystallization. Additionally dynamic light scattering is combined with fluorescence spectroscopy to investigate amyloid fibril aggregation. Finally, a new technology is presented that demonstrates high-throughput mapping of macromolecule structure by integrating single-molecule fluorescence resonance energy transfer spectroscopy with a microfluidic mixing platform. This lab-on-a-chip platform enables examination of conformational transitions in nucleic acids in response to changes in the chemical and molecular environment in order to create a conformational "phase diagram". In addition to presenting new insight into the mechanism of protein crystallization and protein aggregation, this thesis introduces new technologies for studying biological macromolecule phase transitions.
  • Print
    Ray Hashman Hashemi, William G. Bradley Jr., Christopher J. Lisanti.
    Print2010
  • Digital
    Josselin Garnier (Université Paris Diderot, France), George Papanicolaou (Stanford University, USA).
    Digital : Cambridge2016
    Green's function estimation from noise cross correlations -- Travel time estimation from noise cross correlations using stationary phase -- Overview of conventional sensor array imaging -- Passive array imaging of reflectors using ambient noise illumination -- Resolution analysis for passive array imaging using ambient noise illumination -- Travel time estimation using ambient noise in weakly scattering media -- Correlation-based reflector imaging using ambient noise in weakly scattering media -- Virtual source imaging in homogeneous media -- Virtual source imaging in scattering media -- Imaging with intensity cross correlations -- A review of wave propagation in random media.
  • Digital
    edited by David L. Andrews.
    Digital : Wiley2015
  • Digital
    edited by David L. Andrews.
    Digital : Wiley2015
  • Digital
    by Gopal B. Saha.
    Digital : Springer2013
    Structure of Matter -- Radioactive Decay -- Kinetics of Radioactive Decay -- Statistics of Radiation Counting -- Production of Radionuclides -- Interaction of Radiation with Matter -- Gas-Filled Detectors -- Scintillation and Semiconductor Detectors -- Gamma Cameras -- Performance Parameters of Gamma Cameras -- Digital Computers in Nuclear Medicine -- Single Photon Emission Computed Tomography -- Positron Emission Tomography -- Internal Radiation Dosimetry -- Radiation Biology -- Radiation Regulations and Protection.
  • Digital
    James E. Martin.
    Digital : Wiley2013
    Structure of atoms -- Atoms and energy -- Radioactive transformation -- Interactions -- Nuclear fission and its products -- Naturally occurring radiation and radioactivity -- Interactions of radiation with matter -- Radiation shielding -- Internal radiation dose -- Environmental dispersion -- Nuclear criticality -- Radiation detection and measurement -- Statistics in radiation physics -- Neutrons -- Answers to selected problems -- Appendix A -- Appendix B -- Appendix C -- Appendix D -- Index.
  • Digital
    Aman Kalsi, Nikhail Balani.
    Digital : Cambridge2016
    Section 1. Mathematical concepts -- Section 2. Heat, temperature and humidity -- Section 3. Gases, vapours and liquids -- Section 4. Electricity and magnetism -- Section 5. Biological signals -- Section 6. Waves, light and sound -- Section 7. Gas analysis -- Section 8. Suction, CO2 absorption and cleaning -- Section 9. Radiology.
  • Digital
    Caterina La Porta, Università degli Studi di Milano, Stefano Zapperi, IENI-CNR, Milan.
    Digital : Cambridge2017
    Recent years have witnessed an increasing number of theoretical and experimental contributions to cancer research from different fields of physics, from biomechanics and soft-condensed matter physics to the statistical mechanics of complex systems. Reviewing these contributions and providing a sophisticated overview of the topic, this is the first book devoted to the emerging interdisciplinary field of cancer physics. Systematically integrating approaches from physics and biology, it includes topics such as cancer initiation and progression, metastasis, angiogenesis, cancer stem cells, tumor immunology, cancer cell mechanics and migration. Biological hallmarks of cancer are presented in an intuitive yet comprehensive way, providing graduate-level students and researchers in physics with a thorough introduction to this important subject. The impact of the physical mechanisms of cancer are explained through analytical and computational models, making this an essential reference for cancer biologists interested in cutting-edge quantitative tools and approaches coming from physics.
  • Digital
    Val M. Runge, Wolfgang R. Nitz, Miguel Trelles, Frank L Goerner.
    Digital : Thieme Book2014
    "The text is organized into concise chapters, each discussing an important point relevant to clinical MR and illustrated with images from routine patient exams. The topics covered encompass the breadth of the field, from imaging basics and pulse sequences to advanced topics including contrast-enhanced MR angiography, spectroscopy, perfusion, and advanced parallel imaging techniques. Discussion of the latest hardware and software innovations--for example, MR-PET, interventional MR, compressed sensing, and multishot EPI--is included because these topics are critical to current and future advances. Included in the third edition are a large number of new topics, keeping the text up-to-date in this increasingly complex field. The text has also been revised to include additional relevant clinical images, to improve the clarity of descriptions, and to increase the depth of content"--Provided by publisher.
  • Digital
    [edited by] Magnus Dahlbom.
    Digital : CRCnetBASE2017
    Principles of SPECT and PET imaging / Magnus Dahlbom and Michael A. King -- Scintillators for PET and SPECT / Charles L. Melcher -- Photodetectors / Magnus Dahlbom -- Acquistion electronics / Thomas K. Lewellen -- SPECT instrumentation / Wei Chang, Michael Rozler, and Scott D. Metzler -- PET instrumentation / Andrew L. Goertzen and Jonathan D. Thiessen -- SPECT corrections: quantitative SPECT / Irène Buvat -- PET corrections/quantitative PET / Suleman Surti -- Image reconstruction for PET and SPECT / Richard M. Leahy, Bing Bai, and Evren Asma -- High-performance computing in emission tomography / Guillem Pratx -- Methods and applications of dynamic SPECT imaging / Anna M. Celler, Troy H. Farncombe, Alvin Ihsani, Arkadiusz Sitek and R. Glenn Wells -- Dynamic PET imaging / Sung-Cheng Huang and Koon-Pong Wong -- PET/CT / Søren Holm, Osama Mawlawi, and Thomas Beyer -- SPECT/CT / Yothin Rakvongthai, Jinsong Ouyang, and Georges El Fakhri -- PET/mri instrumentation and applications / Ciprian Catana and Leon Menezes -- Preclinical PET and SPECT / Steven R. Meikle, Andre Z. Kyme, Peter Kench, Frederic Boisson, Arvind Parmar -- Clinical applications of PET-CT and SPECT-CT imaging / Johannes Czernin, Ora Israel, Ken Herrmann, Martin Barrio, David Nathanson, and Martin Allen-Auerbach.
  • Digital
    Leonardo Rossi ... [et al.].
    Digital : Springer2006
  • Digital
    Alexander Fridman and Gary Friedman.
    Digital : Wiley2013
    Introduction to fundamental and applied aspects of plasma medicine -- Fundamentals of plasma physics and plasma chemistry relevant to biological and medical applications -- Selected concepts in biology and medicine for physical scientists -- Major plasma disharges and their applicability for plasma medicine -- Mechanisms of plasma interactions with cells -- Plasma sterilization of different surfaces and living tissues -- Plasma decontamination of water and air streams -- Plasma treatment of blood : non-thermal plasma-assisted blood coagulation and plasma control of blood properties -- Plasma assisted healing and treatment of diseases -- Plasma pharmacology -- Fundamentals of plasma-assisted tissue engineering and plasma processing of polymers.
  • Digital
    Sonja Dieterich, Eric Ford, Daniel Pavord, Jing Zeng.
    Digital : ClinicalKey2016
    Reference dosimetry for ionizing radiation -- Relative dosimetry for MV beams -- In-vivo dosimetry -- Quality assurance and commissioning of new radiotherapy technology -- Quality assurance of radiotherapy dose calculations -- Immobilization techniques in radiotherapy -- Image guidance and localization technologies for radiotherapy -- Brachytherapy -- Proton radiotherapy -- Radiation safety and shielding in radiotherapy -- Information technology in radiation oncology -- Quality and safety improvement in radiation oncology -- Simulation for radiotherapy treatment planning -- Treatment planning and quality metrics -- The use of electrons for external beam radiotherapy -- IMRT and VMAT -- SRS and SBRT -- Clinical aspects of image guidance and localization in radiotherapy -- Respiratory motion management for external beam radiotherapy -- Intracavitary brachytherapy -- Interstitial brachytherapy -- Prostate seed implant -- Intraoperative radiotherapy (IORT) -- Special procedures -- Resource documents.
  • Digital
    José A. Gutierrez, Brian S.R. Armstrong.
    Digital : Springer2008
  • Print
  • Digital
    Walter Huda.
    Digital : Ovid2016
    "This book remains focused on imaging using X-rays (i.e., projection radiography, fluoroscopy, and CT), as well as nuclear medicine, ultrasound, and MR"--Provided by publisher.
  • Digital
    W.C.K. Poon, D. Andelman, [editors].
    Digital : CRCnetBASE2006
  • Digital
    edited by Ute Resch-Genger.
    Digital : Springer2008
  • Digital
    Yen Ling Adelene Sim.
    Digital2012
    RNA is an important biological macromolecule that carries out a variety of roles in the cell. To function, RNA needs to fold into precise three-dimensional structures. Different physical forces like entropy, base-pairing and stacking interactions, tertiary contacts and electrostatics affect this folding process. In the first part of this thesis, we focus on nucleic acid electrostatics; RNA molecules have negatively charged backbones that require counterions to neutralize charge-repulsion and facilitate folding. We discuss the ion conditions necessary for a riboswitch (gene-regulating RNA found on 5' or 3' ends of messenger RNA) folding, studied how the flexibility of single stranded DNA is affected by the presence of different amounts of counterions and present a benchmark experimental dataset that can be used for direct comparison to electrostatic theories. The second part of the thesis deals with computational and analysis tools developed to model and understand nucleic acid systems with the ultimate goal of being able to predict RNA structure. Since RNA typically folds hierarchically, we devised a general hierarchical sampling protocol that naturally explores RNA three-dimensional conformational space efficiently and can be used in concert with any force field, such as an RNA knowledgebased potential that we also discuss in this thesis. Additionally, we examined a clustering method that can assist analysis of structural models. Lastly, we applied our modeling techniques to study simple two-way RNA junctions with all-atom representation, and probed the modeled effects of sterics, chain connectivity and sequence on dynamic RNA behavior.
  • Digital
    Adam Richard Sciambi.
    Digital2012
    Two dimensional electron systems (2DESs) at semiconductor interfaces are a useful medium for studying complex physics due to their very low disorder and relative simplicity. Many interesting effects, such as the quantum Hall effect, have been discovered through transport measurements in such systems. Unfortunately, the interfacial nature of 2DESs and the related surface energy barrier means that directly accessing them from the surface is difficult. This has limited our understanding of theoretically-predicted, spatially-organized effects such Wigner-crystal microemulsions and quantum Hall stripes, which have been probed only indirectly. In this dissertation, we develop a new type of local probe that circumvents the surface barrier by tunneling into a 2DES from a second 2DES grown nearby. The interlayer tunneling happens directly below a scanned metal tip outside the sample, behaving as a virtual tip in a system we call Virtual Scanning Tunneling Microscopy (VSTM). In the first half of the dissertation, we discuss a novel mechanism for tuning tunneling locally between two 2DESs. Its premise is that raising a quantum potential well next to an adjacent barrier is energetically similar to lowering the barrier relative to a fixed well. A lower barrier leads to the quantum well wave function extending into it and to increased tunneling into a second quantum well on the opposite side. We characterize this mechanism in a GaAs-AlGaAs heterostructure as a new type of transistor. In the second half of the dissertation, results from a working VSTM system are presented, with local interlayer tunneling revealing hidden features in the interfaces below the surface.
  • Digital
    edited by Chris D. Geddes.
    Digital : Springer2008

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