Books by Subject
- Active pharmaceutical ingredients ......
- — Modified-release drug delivery techno...
- Molecular pathomechanisms and new tre...
- — Write it down. 2nd ed. .................
- Active pharmaceutical ingredients 2005, CRCnetBASE
- Advanced pharmaceutics 2004, CRCnetBASE
- Adverse drug reactions 2010, SpringerPt. 1. Target organ toxicity. -- Drug-induced liver injury / Michael Holt, Cynthia Ju.-- Drug herpersensitivity reactions involving skin / Oliver Hausmann, Benno Schnyder, Werner J. Pichler.-- Adverse drug reactions affecting blood cells / Richard H. Aster.-- Molecular mechanisms of adverse drug reactions in cardiac tissue / Reza Tabrizchi.-- Mechanisms of drug-induced nephrotoxicity / Thomas D. Nolin, Jonathan Himmelfarb.-- Receptor- and reactive intermediate-mediated mechanisms of teratogenesis / Peter G. Wells, Crystal J.J. Lee, Gordon P. McCallum, Julia Perstin, Patricia A. Harper.-- Pt. II. Mediators/Biochemical pathways.-- Role of reactive metabolites in drug-induced hepatotoxicity / A.M. Srivastava, J. L. Maggs, D. J. Antoine, D. P. Williams, D. A. Smith, B. K. Park.-- Role of cytokines in the mechanism of adverse drug reactions / Mary Jane Masson, Lindsay A. Collins, Lance R. Poh.-- Keap1-Nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity / Ian M. Copple, Christopher E. Goldring, Neil R. Kitteringham, B. Kevin Park.-- Signal transduction pathways involved in drug-induced liver injury / Derick Han, Mie Shinohara, Maria D. Ybanez, Behnam Saberi, Neil Kaplowitz.-- Mictrochondrial involvement in drug-induced liver injury / Dominique Pessayre, Abdellah Mansouri, Alain Berson, Bernard Fromenty.-- Pt. III. Examples/Models.-- Mechanisms of acetaminophen-induced liver necrosis / Jack A. Hinson, Dean W. Roberts, Laura P. James.-- Drug-induced liver injury in humans: the case of Ximelagtran / M. Keisu, T.B. Andersson.-- Troglitazone / Tsuyoshi Yokoi.-- Neviropine hypersensitivity / M. Popovic, J.M. Shenton, J. Chen, A. Baban, T. Tharmanathan, B. Mannargudi, D. Abdulla, J.P. Uetrecht.-- Mechanisms of adverse drug reactions to biologics / Janet B. Clarke.-- Pt. IV. Risk factors/Screening drug candidates.-- Pharmacogenetics of idiosyncratic adverse drug reactions / Munir Pirmohamed.-- Danger hypothesis applied to idiosyncratic drug reactions / Jinze Li, Jack P. Uetrecht.-- Approaches for minimizing metabolic activation of new drug candidates in drug discovery / Sanjeev Kumar, Kaushik Mitra, Kelem Kassahun, Thomas A. Baillie.
- Allosteric receptor modulation in drug targeting 2006, CRCnetBASE
- Analytical techniques for biopharmaceutical development 2005, CRCnetBASE
- Anticoagulants, antiplatelets, and thrombolytics 2004, Springer Protocols
- Assessing bioavailability of drug delivery systems 2005, CRCnetBASE
- Biocatalysis in the pharmaceutical and biotechnology industries 2007, CRCnetBASEch. 1. Nitrilases and nitrile hydratases / Robert DiCosimo -- ch. 2. Biocatalytic deracemization : dynamic resolution, stereoinversion, enantioconvergent processes, and cyclic deracemization / Yolanda Simeo, Wolfgang Kroutil, and Kurt Faber -- ch. 3. A decade of biocatalysis at Glaxo Wellcome / Mahmoud Mahmoudian -- ch. 4. Biocatalysis for synthesis for chiral pharamaceutical intermediates / Ramesh N. Patel -- ch. 5. Directed evolution of lipases and esterases for organic synthesis / Aurelio Hidalgo and Uwe T. Bornscheuer -- ch. 6. Flavin-containing oxidative biocatalysts / Marco W. Fraaije and Willem J.H. van Berkel -- ch. 7. Preparation of chiral pharmaceuticals through enzymatic acylation of alcohols and amines / Vicente Gotor-Fernandez, Francisca Rebolledo, and Vicente Gotor -- ch. 8. Dynamic kinetic resolution and asymmetric transformations by enzyme-metal combinations / Mahn-Joo Kim, Yangsoo Ahn, and Jaiwook Park -- ch. 9. Biotransformation of natural or synthetic compounds for the generation of molecular diversity / Robert Azerad -- ch. 10. Applications of aromatic hydrocarbon dioxygenases / Rebecca E. Parales and Sol M. Resnick -- ch. 11. A genomic approach to investigating baker's yeast reductions / Jon D. Stewart -- ch. 12. Immobilization of enzymes as cross-linked enzyme aggregates : a simple method for improving performance / Roger A. Sheldon -- ch. 13. Biotechnological applications of aldolases / Wolf-Dieter Fessner and Stefan Jennewein -- ch. 14. Enzymatic synthesis of modified nucleosides / Luis A. Condezo ... [et al.] -- ch. 15. Biocatalytic reduction of carbozylic acids : mechanism and applications / Padmesh Venkitasubramanian, Lacy Daniels, and John P.N. Rosazza -- ch. 16. Dehalogenases in biodegradation and biocatalysis / Dick B. Janssen -- ch. 17. Enzymatic synthesis of sugar esters and oligosaccharides from renewable resources / A. Ballestros ... [et al.] -- ch. 18. Efficient methods and instrumentation for engineering custom enzymes / Steven J. Robles, William J. Coleman, and Mary M. Yang -- ch. 19. Deaminating enzymes of the purine cycle as biocatalysts for chemoezymatic synthesis and transformation of antiviral agents structurally related to purine nucleosides / Enzo Santaniello, Pierangela Ciuffreda, and Laura Alessandrini -- ch. 20. Mircobial and enzymatic processes for the production of chiral compounds / Kohsuke Honda ... [et al.] -- ch. 21. Discovery of arylmalonate decarbozylase and conversion of the function by rational design / Kenji Miyamoto and Hiromichi Ohta -- ch. 22. Chemoenzymatic preparation of enantiopure building blocks of synthetic utility / Kenji Mori -- ch. 23. Stereoselective modifications of polyhydorxylated steroids / Elena Fossati and Sergio Riva -- ch. 24. Recent developments in enzymatic acyloin condensations / Owen Ward and Ajay Singh -- ch. 25. Synthesis of chiral alcohols with carbonyl reductase library and robust NAD(P)H regenerating system / Hiroaki Yamamoto and Akinobu Matsuyama -- ch. 26. Comparative analysis of chemical and biocatalyic syntheses of drug intermediates / Michael J. Homann ... [et al.] -- ch. 27. Industrial processes using lyases fo C-C, C-N, and C-O bond formation / Martina Pohl an Andreas Lieses -- ch. 28. State of the art and applications in stereoselective synthesis of chiral cyanohydrins / Franz Effenberger, Siegfried Forster, and Christoph Kobler -- ch. 29. Chiral switches : problems, strategies, opportunities, and experiences / Rene Csuk -- ch. 30. Enzyme evolution for chemical process applications / Gjalt W. Huisman and James J. Lalonde -- ch. 31. Biocatalytic routes to nonracemic chiral amines / Nicholas J. Turner and Reuban Carr -- ch. 32. Enantioselective biocatalytic reduction of ketones for the synthesis of optically active alcohols / Stefan Buchholz and Harald Groger -- ch. 33. Enyzmes catalysis in nonaqueous media : past, present and future / Susanne Dreyer ... [et al.] -- ch. 34. Biocatalyic concepts for the synthesis of optically active amines / Stefan Buchholz and Harald Groger.
- Biochips as pathways to drug discovery 2007, CRCnetBASE
- Biomarkers in clinical drug development 2003, CRCnetBASE
- "... provides an established, recognized, authoritative and comprehensive source on medicinal chemistry and drug discovery and development. This flagship reference for medicinal chemists and pharmaceutical professions has been thoroughly updated and expanded across 8 volumes to incorporate the entire process of drug development (preclinical testing, clinical trials, etc.) alongside the traditional strengths in medicinal chemistry and drug discovery"--Provided by publisher.
- Cell culture technology for pharmaceutical and cell-based therapies 2005, CRCnetBASE
- Challenges for the FDA 2007, NAP
- Chemical and pharmaceutical industry in China 2005, Springer
- Chemistry and molecular aspects of drug design and action 2008, CRCnetBASEInflammatory mechanisms in Alzheimer's disease and other neurodegenerative disorders / Joseph Rogers ... [et al.] -- Treatment development strategies for Alzheimer's disease / Ernst Wulfert -- Lipoprotein-associated phospholipase A as a new prognostic factor for coronary artery disease / Alexandros D. Tselepis -- New molecular targets for the prevention and treatment of gastrointestinal ulcers and inflammation / Sandor Szabo ... [et al.] -- Stress activates corticotropin releasing : factor signaling pathways : implication in functional bowel disorders / Yvette Tache -- Design, synthesis, and pharmacological evaluation of high-affinity and selectivity sigma-1 and sigma-2 receptor ligands / Jacques H. Poupaert -- Synthesis of biologically active taxoids / K.C. Nicolaou and R.K. Guy -- From the molecular pharmacology to the medicinal chemistry of cannabinoids / Didier M. Lambert -- An appraisal of fomocaines : current situation and outlook / Herbert Oelschlager and Andreas Seeling -- Ligands for the GABA recognition site at the GABAA receptor : structure-activity studies / Bente Frlund ... [et al.] -- Strategies for development of new lead structures for inhibition of acetylcholinesterase / Petra Kapkova ... [et al.] -- Discovery of potent and selective inhibitors of human aldosterone synthase (CYP11B2) : a new target for the treatment of congestive heart failure and myocardial fibrosis--a review / R.W. Hartmann ... [et al.] --Thiocarboxanilides : a new class of nonnucleoside reverse transcriptase inhibitors (NNRTIs) with great potential for the treatment of human immunodeficiency virus type 1 (HIV-1) infections / E. De Clercq, A. Karlsson, and J. Balzarini -- Histamine H-receptor agonists and antagonists : chemical, pharmacological, and clinical aspects / Holger Stark and Walter Schunack -- Anti-inflammatory actions of flavonoids and structural requirements for new design / Theoharis C. Theoharides -- Molecular mechanisms of HO-induced DNA damage : the action of desferrioxamine / M. Tenopoulou, P.-T Doulias, and D. Galaris -- LNA (locked nucleic acid) and functionalized LNA : towards efficient gene targeting / Jesper Wengel -- The effect of diet on drug metabolism / K.J. Netter -- Cytochromes P450 in the metabolism and bioactivation of chemicals / Costas Ioannides -- In vitro methods to measure drug metabolism and drug interactions in drug discovery and development / O. Pelkonen ... [et al.] -- How to probe the sites of action of drug molecules / A. Makriyannis and F. Bitter -- Physicochemical profiling in early drug discovery : new challenges at the age of high-throughput screen and combinatorial chemistry / Bernard Faller -- Drug membrane interaction and its importance for drug efficacy / J.K. Seydel ... [et al.] -- The fight against AIDS : new avenues for inhibiting reverse transcriptase (RT), and old target / Maurizio Botta ... [et al.].
- Chiral separations 2003, Springer Protocols
- Chiral separations by liquid chromatography and related technologies 2003, CRCnetBASE
- Clinical skills for pharmacists. 3rd ed. 2012, ScienceDirectIntroduction : the practice of clinical pharmacy -- Communication skills for the pharmacist -- Taking medication histories -- Physical assessment skills -- Review of laboratory and diagnostic tests -- The patient case presentation -- Therapeutics planning -- Monitoring drug therapies -- Researching and providing drug information -- Ethics in pharmacy and health care.
- Clinical trials of drugs and biopharmaceuticals 2006, CRCnetBASE
- Combination products 2008, CRCnetBASEOverview of combination products -- Ensuring successful combination product development -- Overview of FDA and other regulatory agency expectations -- Resource requirements -- Manufacturing of combination products -- Challenges and pitfalls to avoid with combination products -- Postlaunch compliance requirements -- Agency audits and challenges.
- Computational medicinal chemistry for drug discovery 2004, CRCnetBASE
- Controlled release in oral drug delivery 2011, Springer
- Cosmeceuticals and active cosmetics. 2nd ed. 2005, CRCnetBASE
- Introduction / Wayne R. Gombotz and Steven J. Shire -- Design of therapeutic MABS. CDR repair: a novel approach to antibody humanization / Mark S. Dennis -- Nanobodies, single-domain antigen-binding fragments of camelid heavy-chain antibodies / Gholamreza Hassanzadeh Ghassabeh, Serge Muyldermans, and Dirk Saerens -- Expression and production of MABS. GPEx® a flexible method for the rapid generation of stable, high expressing, antibody producing mammalian cells lines / Gregory T. Bleck -- Advancing our cell culture platform: incorporating lessons learned and new technologies / Carole Heath -- Recovery and purification. Addressing changes associated with technology transfer: a case study / Michele M. Myers ... [et al.] -- Concepts for disposables in biopharmaceutical manufacture / Joachim K. Walter and Uwe Gottschalk -- Formulation and delivery. Formulation and delivery issues for monoclonal antibody therapeutics / Ann L. Daugherty and Randall J. Mrsny -- Challenges in the development of high protein concentration formulations / Steven J. Shire, Zahra Shahrock, and Jun Liu -- Protein immobilization by crystallization and precipitation: an alternative to lyophilization / Karoline Bechtold-Peters -- Analytics and specification setting for MABS. Characterizing high affinity antigen/antibody complexes by kinetic and equilibrium based methods / Andrew W. Drake, David G. Myszka, and Scott L. Klakamp -- Analytical characterization of monoclonal antibodies: linking structure to function / Reed J. Harris ... [et al.] -- Analysis of irreversible aggregation, reversible self-association and fragmentation of monoclonal antibodies by analytical ultracentrifugation / James D. Andya, Jun Liu, and Steven J. Shires -- Biophysical signatures of monoconal antibodies / N. Harn ... [et al.] -- Pharmacokinetics and immunogenicity. Impact of Fc glycosylation on monoclonal antibody effector functions and degradation by proteases / T. Shantha Raju -- Immunogenicity assessment of antibody therapeutics / P. stas, Y. Gansemans, and I. Lasters -- Armed antibodies and new classes of antibodies. Production of monoclonal antibodies in E. coli / Dorothea E. Reilly and Daniel G. Yansura -- Recent advances in the use of antibody drug conjugates for cancer theapy / Peter D. Senter -- Antibody radiolabeling / Corinne Bensimon and Russell Redshaw.
- Depression 2010, KargerAntidepressant compounds : a critical review / S.W. Tang, D.M. Helmeste, B. Leonard -- The hypothalamic-pituitary-adrenal axis in depression / M. Julio-Pieper, T.G. Dinan -- Dysfunctional circadian rhythms and mood disorders : opportunities for novel therapeutic approaches / T.R. Norman -- The concept of depression as a dysfunction of the immune system / B.E. Leonard -- The role of polyunsaturated fatty acids in the pathology and treatment of depression / C. Song -- Overcoming antidepressant treatment resistance : focus on glutamate / J.W. Murrough, S.J. Mathew -- Neuroimaging and the pathophysiology and treatment of depression : recent advances and future needs / D.M. Cannon -- Animal models of depression : where are we going? / D.A. Slattery, J.F. Cryan -- Genetic models of depression and antidepressant response / I. Lucki -- The role of 5-HT2C receptors in the antidepressant response : a critical review / C.B.P. Martin ... [et al.] -- Chromatin-based treatments for affective disorders : insight or utopia / H.E. Covington III, O. Berton -- Neurotrophic factors and antidepressant action : recent advances / O.F. O'Leary, E. Castron -- Neurogenic basis of antidepressant action : recent advances / A. Tanti, C. Belzung -- The nature and treatment of therapy-resistant depression / S.H. Kennedy, S.J. Rizvi, P. Giacobbe -- Optimizing antidepressant management of depression : current status and future perspectives / T.L. Schwartz, S.M. Stahl.
- Developing solid oral dosage forms. 1st ed. 2009, ScienceDirect
- Directory of approved biopharmaceutical products 2005, CRCnetBASE
- Dose finding in drug development 2006, Springer
- Dose optimization in drug development 2006, CRCnetBASE
- Drug bioavailability 2003, WileyPart I. Studies of Membrane Permeability and Oral Absorption -- ch. 1. Physico-Chemical Approaches to Drug Absorption / Han van de Waterbeemd, p. 1-20 -- ch. 2. High-Throughput Measurement of log D and pKa / John E. A. Comer, p. 21-45 -- ch. 3. High-throughput Measurement of Permeability Profiles / Alex Avdeef, p. 46-71 -- ch. 4. Caco-2 and Emerging Alternatives for Prediction of Intestinal Drug Transport: A General Overview / Per Artursson and Staffan Tavelin, p. 72-89 -- ch. 5. Cell Cultures in Drug Discovery: An Industrial Perspective / Anna-Lena Ungell and Johan Karlsson, p. 90-131 -- ch. 6. Use of Animals for the Determination of Absorption and Bioavailability / Chris Logan, p. 132-154 -- ch. 7. In Vivo Permeability Studies in the Gastrointestinal Tract of Humans / Niclas Petri and Hans Lennernäs, p. 155-188 -- Part II. Drug Dissolution and Solubility -- ch. 8. Gastrointestinal Dissolution and Absorption of Drugs / Gladys E. Granero, Chandrasekharan Ramachandran and Gordon L. Amidon, p. 189-214 -- ch. 9. Aqueous Solubility in Discovery, Chemistry, and Assay Changes / Chris Lipinski, p. 215-231 -- ch. 10. Factors Influencing the Water Solubilities of Crystalline Drugs / James W. McFarland, Chau M. Du and Alex Avdeef, p. 232-242 -- Part III. Role of Transporters and Metabolism in Oral Absorption -- ch. 11. Transporters in the GI Tract / Ho-Chul Shin, Christopher P. Landowski, Duxin Sun and Gordon L. Amidon, p. 243-287 -- ch. 12. Hepatic Transport / Hiroshi Suzuki and Yuichi Sugiyama, p. 288-310 -- ch. 13. The Importance of Gut Wall Metabolism in Determining Drug Bioavailability / Kevin Beaumont, p. 311-328 -- ch. 14. Modified Cell Lines / Charles L. Crespi, p. 329-338 -- Part IV. Computational Approaches to Drug Absorption and Bioavailability -- ch. 15. Intestinal Absorption: The Role of Polar Surface Area / Per Artursson and Christel A. S. Bergström, p. 339-357 -- ch. 16. Calculated Molecular Properties and Multivariate Statistical Analysis in Absorption Prediction / Ulf Norinder and Markus Haeberlein, p. 358-405 -- ch. 17. VOLSURF: A Tool for Drug ADME-Properties Prediction / Gabriele Cruciani, Mirco Meniconi, Emanuele Carosati, Ismael Zamora and Raimund Mannhold, p. 406-419 -- ch. 18. Simulation of Absorption, Metabolism, and Bioavailability / Michael B. Bolger, Balaji Agoram, Robert Fraczkiewicz and Boyd Steere, p. 420-443 -- ch. 19. Prediction of Bioavailability / Arun K. Mandagere and Barry Jones, p. 444-460 -- ch. 20. Towards P-Glycoprotein Structure-Activity Relationships / PD Anna Seelig, Ewa Landwojtowicz, Holger Fischer and Xiaochun Li Blatter, p. 461-492 -- Part V. Drug Development Issues -- ch. 21. Application of the Biopharmaceutic Classification System Now and in the Future / Bertil Abrahamsson and Hans Lennernäs, p. 493-531 -- ch. 22. Prodrugs / Bente Steffansen, Anne Engelbrecht Thomsen and Sven Frokjaer, p. 532-546 -- ch. 23. Modern Delivery Strategies: Physiological Considerations for Orally Administered Medications / Clive G. Wilson, p. 547-568.
- Drug delivery to the oral cavity 2005, CRCnetBASE
- Drug discovery handbook 2005, WileyIntroduction. Drug discovery in the 21st century --ch. 1.Natural products /Charles B. Spainhour --ch. 2.Cancer cell proteomics using molecular aptamers /Weihong Tan ... [et al.] --ch. 3.Molecular similarity methods and QSAR models as tools for virtual screening /Jürgen Bajorath --ch. 4.Systems biology : applications in drug discovery /Sean Ekins ...[et al.] --ch. 5.High throughput flow cytometry /Larry A. Sklar ... [et al.] --ch. 6.Combining NMR spectral information with associated structural features to form computationally nonintensive, rugged, and objective models of biological activity /Richard D. Beger, Dan A. Buzatu, and Jon G. Wilkes --ch. 7.Using Microsoft Excel as a laboratory data management tool /A. Erik Rubin, Mark F. Russo, and William Neil --ch. 8.Age of regulation /Sandy Weinberg and Gerald J. Whartenby --ch. 9.Simultaneous screening of multiple cell lines using the CellCard system /Oren E. Beske --ch. 10.Protein X-ray crystallography in drug discovery /Peter Nollert ... [et al.] --ch. 11.Biological and chemistry assays available during drug discovery and developability assessment /Duane B. Lakings --ch. 12.Strategies and methods in monitoring and targeting protein-protein interactions /Arianna Loregian and Giorgio Palù --ch. 13.High-throughput screening : evolution of technology and methods --Martyn N. Banks ... [et al.] --ch. 14.Metal-enhanced fluorescence : application to high-throughput screening and drug discovery /Kadir Aslan ... [et al.] --ch. 15.Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays /Brian J. Eastwood ... [et al.] --ch. 16.Coupled luminescent methods in drug discovery : 3-minute assays for cytotoxicity and phosphatase activity /Michael J. Corey and Robert J. Kinders --ch. 17.Design and pharmaceutical applications of prodrugs /Tomi Järvinen ... [et al.] --ch. 18.GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders /Ulf Madsen ... [et al.] --ch. 19.Cardiac sarcolemmal ATP-sensitive potassium channel antagonists : novel ischemia-selective antiarrhythmic agents /George E. Billman --ch. 20.Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid, and anticoagulant therapies for sepsis /Peter C. Minneci ... [et al.] --ch. 21.Combinatorial chemistry in the drug discovery process /Nathan T. Ross, Brian R. McNaughton, and Benjamin L. Miller --ch. 22.Herbal medicines and animal models of gastrointestinal diseases /C.H. Cho and J.K.S. Ko --ch. 23.Endocrine and metabolic agents /Brian L. Furman --ch. 24.Respiratory viruses /Paul D. Olivo --ch. 25.Strategies in the design of antiviral drugs /Erik De Clercq and Piet Herdewijn --ch. 26.Protein kinase inhibitors in drug discovery /Keykavous Parang and Gongqin Sun --ch. 27.RNA-based therapies /Steve Pascolo --ch. 28.Novel imaging agents for molecular MR imaging of cancer /Dmitri Artemov and Zaver M. Bhujwalla --ch. 29.Targets and approaches for cancer drug discovery /Susan L. Mooberry.
- Drug discovery strategies and methods 2004, CRCnetBASE
- Drug interactions in infectious diseases. 3rd ed. 2011, SpringerIntroduction to Drug-Drug Interactions -- Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion -- Mechanisms of Drug Interactions II: Transport Proteins -- Drug-Food Interactions -- Interactions Between Herbs and Antiinfective Medications -- Drug-Cytokine Interactions -- Beta-Lactam Antibiotics -- Macrolides, Azalides, and Ketolides -- Quinolones -- Glycopeptides, Lipopeptides, and Lipoglycopeptides -- Miscellaneous Antibiotics -- Drugs for Tuberculosis -- Drug Interactions with Antiretrovirals for HIV Infection -- Non-HIV Antiviral Agents -- Antifungal Agents -- Antimalarial Agents -- Antiprotozoal and Anthelmintic Agents -- Drug Interaction Considerations Throughout Drug Development -- Probe Cocktail Studies -- Design and Data Analysis in Drug Interaction Studies.
- Drug metabolism and pharmacokinetics quick guide 2011, Springer
- Drug metabolizing enzymes 2003, CRCnetBASE
- Drug misuse and community pharmacy 2003, CRCnetBASE
- Drug products for clinical trials. 2nd ed. 2006, CRCnetBASE
- Enhancement in drug delivery 2007, CRCnetBASE
- Introduction to the guidelines. Purpose, target and scope -- Background -- A dual obligation, a quadruple imperative -- Indispensability of controlled medicines in contemporary medical practices -- Safety of controlled medicines -- Current availability -- Impediments to availability, accessibility and affordability -- Why and how to work with this document? -- Guidelines for ensuring balance in national policies on controlled substances. Content of drug control legislation and policy -- Authorities and their role in the system -- Policy planning for availability and accessibility -- Healthcare professionals -- Estimates and statistics -- Procurement -- Other -- Country assessment checklist.
- Enzymes and their inhibition 2005, CRCnetBASE
- Essentials of pharmacy law 2003, CRCnetBASE
- Facility validation 2004, CRCnetBASE
- FDA regulatory affairs 2004, CRCnetBASE
- FDA-speak. 2nd ed. 2002, CRCnetBASE
- Formulating poorly water soluble drugs 2012, Springer1. Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs / Stephanie Bosselmann and Robert O. Williams III -- 2. Optimizing the Formulation of Poorly Water-Soluble Drugs / Kevin P. O'Donnell and Robert O. Williams III -- 3. Solid-State Techniques for Improving Solubility / Justin R. Hughey and Robert O. Williams III -- 4. Mechanical Particle-Size Reduction Techniques / Javier O. Morales, Alan B. Watts, and Jason T. McConville -- 5. Solubilized Formulations / Feng Zhang and James C. DiNunzio -- 6. Injectable Formulations of Poorly Water-Soluble Drugs / Michael P. Boquet and Dawn R. Wagner -- 7. Design and Development of Self-Emulsifying Lipid Formulations for Improving Oral Bioavailability of Poorly Water-Soluble and Lipophilic Drugs / Ping Gao -- 8. Structured Development Approach for Amorphous Systems / Navnit Shah, Harpreet Sandhu, Duk Soon Choi, Oskar Kalb, Susanne Page, and Nicole Wyttenbach -- 9. Melt Extrusion / James C. DiNunzio, Feng Zhang, Charlie Martin, and James W. McGinity -- 10. Spray-Drying Technology / Dave A. Miller and Marco Gil -- 11. Pharmaceutical Cryogenic Technologies / Wei Yang, Donald E. Owens III, and Robert O. Williams III -- 12. Precipitation Technologies for Nanoparticle Production / Jasmine M. Rowe and Keith P. Johnston -- 13. Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs / Justin R. Hughey and James W. McGinity -- 14. Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs / Zedong Dong and Hasmukh Patel.
- Functional protein microarrays in drug discovery 2007, CRCnetBASEHigh-throughput gene cloning using the Gateway technology / Scott N. Peterson ... [et al.] -- Protein expression for microarrays / Harry H. Yim, Thomas G. Chappell, and Steven H. Harwood -- Emerging trend: cell-free protein expression / Federico Katzen and Wieslaw Kudlicki -- The critical role of surface chemistry in protein microarrays / Athena Guo and X.-Y. Zhu -- Fabrication of sol-gel-derived protein microarrays for diagnostics and screening / Nicholas Rupcich and John D. Brennan -- Printing and QC of functional protein microarrays / Dee Shen, Fang X. Zhou, and Barry Schweitzer -- Protein engineering for surface attachment / Aparna Girish, Grace Y. J. Chen, and Shao Q. Yao -- Protein in situ arrays through cell-free protein synthesis / Mingyue He ... [et al.] -- Fluorescent detection methods for protein microarrays / Steven Roman and Scott Clarke -- Functional analysis of protein interactions using surface plasmon resonance-based microarrays / Alan McWhirter and Stefan Löfås -- Leaving the surface behind: at the intersection of protein microarrays and mass spectrometry / Darrell P. Chandler ... [et al.] -- High-resolution label-free detection applied to protein microarray research / Lance G. Laing and Brian Cunningham -- Studying protein-protein interactions with protein microarrays: rapid identification of 14-3-3 protein binding partners / Jun-ichi Satoh -- A combined force of chemical genetics and protein microarrays / Heng Zhu and Jing Huang -- Antibody profiling for protein drug development and clinical development / Steve H. Herrmann -- Humoral response profiling using protein microarrays / Arun Sreekumar ... [et al.] -- DNA interactions with arrayed proteins / Marina Snapyan and Vehary Sakanyan -- G protein-coupled receptor microarrays for drug discovery / John Salon ... [et al.] -- Kinase substrate identification using yeast protein microarrays / Geeta Devgan and Michael Snyder -- Protein microarray image analysis / Minzi Ruan -- The analysis of protein arrays / Brad Love -- Evaluating precision and recall in functional protein arrays / Keith Robison -- Visualization of protein microarray data / Kevin Clancy.
- Fundamentals of nuclear pharmacy. 6th ed. 2010, SpringerEstablished as a classic text on nuclear chemistry and pharmacy, 'Fundamentals of Nuclear Pharmacy' has been thoroughly revised and now includes new information covering innovations in imaging technology and clinical applications in the field.
- G protein-coupled receptors in drug discovery 2006, CRCnetBASE
- Gene profiles in drug design 2008, CRCnetBASEA perspective on the future clinical impact of genetic diagnosis and gene-based drug therapies for patient health / Julian W. Tang -- Virally-encoded microRNA (miRNA): candidates for gene silencing / Ralph A. Tripp ... [et al.] -- Development of gene profile-responsive antisense agents / Sergei A. Kazakov and Brian H. Johnston -- Gene profiles in drug development: applications in target identification, biomarker discovery, and compound characterization / Eric A.G. Blomme and Dimitri Semizarov -- Gene profiles and cancer / Beverly A. Teicher -- RNA viruses and RNA-based drugs: a perfect match for RNA delivery and the identification of candidate therapeutic target inflammatory molecules / Brett A. Lidbury ... [et al.] -- Ethical considerations for a genetic future in diagnosis and drug development / Lexie Brans and Brett A. Lidbury.
- Generic drug product development 2005, CRCnetBASE
- Glutamate and GABA receptors and transporters 2002, CRCnetBASE
- Good design practices for GMP pharmaceutical facilities 2005, CRCnetBASE
- Good laboratory practice regulations. 3rd ed. 2003, CRCnetBASE
- Good pharmaceutical manufacturing practice 2005, CRCnetBASE
- Guide to pharmaceutical particulate science 2003, CRCnetBASEParticulate systems: manufacture and characterization -- Sampling and measurement biases -- Particle size descriptors and statistics -- Behavior of particles -- Instrumental analysis -- Methods of particle size measurement and their importance for specific applications (instrument synergy) -- Particle size behavior and physical behavior of a powder -- Clinical effect of pharmaceutical particulate systems.
- Handbook of assay development in drug discovery 2006, CRCnetBASE
- Handbook of bioanalysis and drug metabolism 2004, CRCnetBASE
- Handbook of biogeneric theraupetic proteins 2005, CRCnetBASE
- Handbook of combinatorial chemistry 2002, WileyPart I. General Aspects -- ch. 1. Combinatorial Chemistry in Perspective / K. C. Nicolaou, R. Hanko and W. Hartwig, p. 1-9 -- ch. 2. Introduction to Combinatorial Chemistry / David L. Coffen and Joachim E. A. Luithle, p. 10-23 -- ch. 3. Solid Phase and Soluble Polymers for Combinatorial Synthesis / Rainer Haag, André Hebel and Jean-François Stumbé, p. 24-58 -- ch. 4. Linkers for Solid-Phase Synthesis / Stefan Bräse and Stefan Dahmen, p. 59-169 -- ch. 5. Encoding Technologies / Thomas Krämer, Valery V. Antonenko, Reza Mortezaei and Nicolay V. Kulikov, p. 170-189 -- ch. 6. Instrumentation for Combinatorial Chemistry / Marcus Bauser and Hubertus Stakemeier, p. 190-224 -- Part II. Synthetic Chemistry -- ch. 7. Radical Reactions in Combinatorial Chemistry / A. Ganesan and Mukund P. Sibi, p. 225-246 -- ch. 8. Nucleophilic Substitution in Combinatorial and Solid-Phase Synthesis / Jan-Gerd Hansel and Stephan Jordan, p. 247-269 -- ch. 9. Electrophilic Substitution in Combinatorial and Solid-Phase Synthesis / Jan-Gerd Hansel and Stephan Jordan, p. 270-278 -- ch. 10. Elimination Chemistry in the Solution- and Solid-Phase Synthesis of Combinatorial Libraries / Demosthenes Fokas and Carmen Baldino, p. 279-304 -- ch. 11. Addition to CC Multiple Bonds (Except for CC Bond Formation / Adrian L. Smith, p. 305-321 -- ch. 12. Addition to Carbon-Hetero Multiple Bonds / Philipp Grosche, Jörg Rademann and Günther Jung, p. 322-345 -- ch. 13. Chemistry of the Carbonyl Group / Tobias Wunberg, p. 346-368 -- ch. 14. Oxidation Except CC Double Bonds / Henning Steinhagen, p. 369-386 -- ch. 15. Reductions in Combinatorial Synthesis / Christopher P. Corrette and Conrad W. Hummel, p. 387-439 -- ch. 16. Cycloadditions in Combinatorial and Solid-Phase Synthesis / Markus Albers and Thorsten Meyer, p. 440-469 -- ch. 17. Main Group Organometallics / Christopher Kallus, p. 470-491 -- ch. 18. Enolates and Related Species in Combinatorial and Solid-Phase Synthesis / Jochen Krüger, p. 492-530 -- ch. 19. Solid-Phase Palladium Catalysis for High-Throughput Organic Synthesis / Yasuhiro Uozumi and Tamio Hayashi, p. 531-584 -- ch. 20. Olefin Metathesis and Related Processes for CC Multiple Bond Formation / Florencio Zaragoza, p. 585-609 -- Part III. Special Synthetic Topics -- ch. 21. Solid-Phase Synthesis of Natural Products and Natural Product-Like Libraries / K. C. Nicolaou and Jeffrey A. Pfefferkorn, p. 611-642 -- ch. 22. Solid-Phase Synthesis of Heterocyclic Systems (Heterocycles Containing One Heteroatom / Roland E. Dolle, p. 643-684 -- ch. 23. Multicomponent Reactions / Arounarith Tuch and Stefan Wallé, p. 685-705 -- ch. 24. Strategies for Creating the Diversity of Oligosaccharides / Pamela Sears and Chi-Huey Wong, p. 706-722 -- Part IV. Molecular Design and Combinatorial Compound Libraries -- ch. 25. Design Criteria / Josef Pernerstorfer, p. 723-742 -- ch. 26. Estimation of Physicochemical and ADME Parameters / Michael W. Härter, Jörg Keldenich and Walter Schmitt, p. 743-760 -- ch. 27. Virtual Compound Libraries and Molecular Modeling / Roger M. Brunne, Gerhard Hessler and Ingo Muegge, p. 761-783 -- ch. 28. Erythropoietin Sensitizer - A Case Study / Berthold Hinzen, Gabriele Bräunlich, Christoph Gerdes, Thomas Krämer, Klemens Lustig, Ulrich Nielsch, Michael Sperzel and Josef Pernerstorfer, p. 784-805 -- ch. 29. Estimation of Stability and Shelf Life for Compounds, Libraries, and Repositories in Combination with Systematic Discovery of New Rearrangement Pathways / Ferenc Darvas, György Dorman, Tamás Karancsi, Tamás Nagy and István Bágyi, p. 806-828 -- Part V. Novel Applications of Combinatorial Chemistry -- ch. 30. Concepts of Combinatorial Chemistry in Process Development / Markus Eckert and Ulrich Notheis, p. 829-863 -- ch. 31. High-Throughput Screening Applied to Process Development / Oliver Brümmer, Bernd Jandeleit, Tetsuo Uno and W. Henry Weinberg, p. 864-884 -- ch. 32. Combinatorial Methods in Catalysis / Bill Archibald, Oliver Brümmer, Martin Devenney, Sasha Gorer, Bernd Jandeleit, Tetsuo Uno, W. Henry Weinberg and Thomas Weskamp, p. 885-990 -- ch. 33. Diversity-Based Identification of Efficient Homochiral Organometallic Catalysts for Enantioselective Synthesis / Amir H. Hoveyda, p. 991-1016 -- ch. 34. Combinatorial Aspects of Materials Science / Bill Archibald, Oliver Brümmer, Martin Devenney, Daniel M. Giaquinta, Bernd Jandeleit, W. Henry Weinberg and Thomas Weskamp, p. 1017-1062 -- ch. 35. Reprogramming Combinatorial Biology for Combinatorial Chemistry / Sean V. Taylor, p. 1063-1097.
- Handbook of drug screening 2001, CRCnetBASE
- Handbook of food-drug interactions 2003, CRCnetBASE
- Handbook of pharmaceutical analysis 2002, CRCnetBASE
- Handbook of pharmaceutical granulation technology. 2nd ed. 2005, CRCnetBASE
- Handbook of pharmaceutical manufacturing formulations v. 1-6, 2004., CRCnetBASEv. 2, 2004 CRCnetBASEv. 3, 2004 CRCnetBASEv. 4, 2004 CRCnetBASEv. 5, 2004 CRCnetBASEv. 6, 2004 CRCnetBASEv. 1. Compressed solid products -- v. 2. Uncompressed solid products -- v. 3. Liquid products -- v. 4. Semisolid products -- v. 5. Over-the-counter products -- v. 6. Sterile products.
- Handbook of regression and modeling 2007, CRCnetBASE
- Handbook of topical antimicrobials 2003, CRCnetBASE
- Herbal supplements-drug interactions 2006, CRCnetBASE
- High dilution effects 2004, Springer
- High-throughput analysis in the pharmaceutical industry 2009, CRCnetBASEHigh throughput sample preparation techniques and their application to bioanalytical protocols and purification of combinatorial libraries / Krishna Kallury -- High-throughput quantitative bioanalysis / Katty X. Wan -- Optimizing LCMS equipment to increase throughput in pharmaceutical analysis / Michael G. Frank and Douglas E. Mcintyre -- Throughput improvement of bioanalytical LC-MS/MS by sharing of detector between HPLC systems / Min Shuan Chang and Tawakol El-Shourbagy -- High throughput strategies for metabolite identification in drug discovery / Patrick J. Rudewicz, Qin Yue, and Young Shin -- Utilizing micro parallel liquid chromatography for high-throughput analyses in the pharmaceutical industry / Sergio A. Guazzotti -- Strategies and techniques for higher throughput ADME/PK assays / Walter Korfmacher -- High-throughput analysis in drug metabolism during early drug discovery / Yau Yi Lau --High-throughput analysis in the support of process chemistry and formulation research & development in the pharmaceutical industry / Zhong Li -- On-line SPE LC/MS/MS for high throughput bioanalytical analysis / Dong Wei and Liyu Yang -- Applications of high-throughput analysis in therapeutic drug monitoring / Quanyun A. Xu and Timothy L. Madden -- High-throughput quantitative pharmaceutical analysis in drug metabolism and pharmacokinetics (DMPK) using liquid crhomatrography-mass spectrometry / Xiaohui Xu -- Designing high throughput HPLC assays for small and biological molecules / Roger K. Gilpin and Wanlong Zhou -- The advances in capillary and nano-HPLC technology for drug discovery and development / Frank J. Yang and Richard Yu -- High-throughput analysis of complex protein mixtures by mass spectrometry / Kojo S.J. Elenitoba-Johnson.
- High-throughput lead optimization in drug discovery 2008, CRCnetBASEApplication of parallel synthesis to the optimization of inhibitors of the ZipA-FtsZ protein-protein interaction / Lee D. Jennings -- Case studies of parallel synthesis in hit identification, hit exploration, hit-to-lead, and lead optimization programs / Alexander Ernst and Daniel Obrecht -- A successful application of parallel synthesis to computer-assisted structural optimization of new leads targeting human immunodeficiency virus-1 reverse transcriptase : the case of acylthiocarbamates and thiocarbamates / Angelo Ranise, Andrea Spallarossa, and Sara Cesarini -- How high-throughput medicinal chemistry can expedite lead discovery, lead optimization, and beyond / Rongshi Li -- Rapid lead identification of inhibitors of adenine nucleotide translocase: a case study of applying combinatorial chemistry techniques in drug discovery / Yazhong Pei, Walter H. Moos, and Soumitra Ghosh -- Parallel synthesis of anticancer, antiinflammatory, and antiviral agents derived from L- and D-amino acids / Robert C. Reid and David P. Fairlie -- Application of solid-phase parallel synthesis in lead optimization studies / Bijoy Kundu -- High-throughput solid-phase synthesis of nucleoside-based libraries in the search for new antibiotics / Dianqing Sun and Richard E. Lee.
- Hooked 2007The Good, the bad, and the ugly : a story of two medications -- An Ethical framework -- The Pharmaceutical industry and the free market -- Patents, generic drugs, and academic science -- Research and profits -- Suppression of research data -- The Quality of pharmaceutical research -- The Drug rep: historical background -- The Drug rep today -- The Influence of drug reps: what the data show -- Continuing medical education -- Professional organizations and journal advertising -- The Industry and the consumer -- The FDA: from patent medicines to AIDS drugs -- The FDA and the industry, 1990-2004 -- Solutions: the management and divestment strategies -- Solutions requiring enhanced professionalism in medicine -- Solutions requiring regulatory reform.
- Immunology for pharmacy 2012, ScienceDirect
- Industrialization of drug discovery 2005, CRCnetBASE
- Injectable dispersed systems 2005, CRCnetBASE
- Integrated drug discovery technologies 2002, CRCnetBASE
- Isolation technology. 2nd ed. 2004, CRCnetBASE
- Law and ethics of the pharmaceutical industry 2006, ScienceDirect
- Ligand-macromolecular interactions in drug discovery 2010, Springer ProtocolsPart I. Reviews -- 1. An Historical overview of drug discovery / Ana Sofia Pina, Abid Hussain, and Ana Cecília Roque -- 2. Ligand macromolecule interactions : theoretical principles of molecular recognition / Tammy Nolan, Nidhi Singh, and Christopher R. McCurdy -- 3. X-Ray cystallography in drug discovery / Ana Luísa Carvalho, José Trincão, and Maria João Romão -- 4. Virtual screening of compound libraries / Nuno M.F.S.A. Cerqueira, Sérgio F. Sousa, Pedro A. Fernandes, and Maria João Ramos -- Part II: Protocols -- 5. Combinatorial chemistry and the synthesis of compound libraries / Rolf Breinbauer and Matthias Mentel -- 6. Ligand-based nuclear magnetic resonance screening techniques / Aldino Viegas, Anjos L. Macedo, and Eurico Cabrita -- 7. Isothermal titration calorimetry and differential scanning calorimetry / Geoff Holdgate -- 8. Adaptive combinatorial design of focused compound libraries / Gisbert Schneider and Andreas Schüller -- 9. Chemical microarrays : a new tool for discovery enzyme inhibitors / Shuguang Liang, Wei Xu, Kurumi Y. Horiuchi, Yuan Wang, and Haiching Ma -- 10. Fluorescence polarization and time-resolved fluorescence resonance energy transfer techniques for PI3K assays / Kurumi Y. Horiuchi and Haiching Ma -- 11. Small molecule protein interaction profiling with functional protein microarrays / Lihao Meng, Dawn Mattoon, and Paul Predki -- 12. Capillary electrophoresis in drug discovery / Milena Quaglia and Ersilia De Lorenzi -- 13. SPR in drug discovery : searching bioactive compounds in plant extracts / Maria Minunni and Anna Rita Bilia -- 14. Application of frontal affinity chromatography with mass spectrometry (FAC-MS) for stereospecific ligand-macromolecule interaction, detection and screening / Jacek Slon-Usakiewicz and Peter Redden -- 15. GPC spin column HPLC-ESI-MS methods for screening drugs noncovalently bound to proteins / Marshall M. Siegel -- 16. A scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening / Yuren Wang and Philip Jones -- 17. A natural products approach to drug discovery : probing modes of action of antitumor agents by genome-scale cDNA library screening / Hendrik Luesch and Pedro Abreu -- 18. Ligand-macromolecule interactions in live cells by fluorescence correlation spectroscopy / Aladdin Pramanik
- Liposome technology. 3rd ed. v. 1-3, 2007, CRCnetBASEv. 2, 2007 CRCnetBASEv. 3, 2007 CRCnetBASEv. 1. Liposome preparation and related techniques -- v. 2. Entrapment of drugs and other materials into liposomes -- v. 3. Interactions of liposomes with the biological milieu.
- Lipospheres in drug targets and delivery 2005, CRCnetBASE
- Lippincott's Nursing drug guide. [12th ed.] 2012, Ovid
- Long acting injections and implants 2012, Springer
- Managing pharmacy practice 2004, CRCnetBASE
- Mass spectrometry in drug discovery 2002, CRCnetBASE
- Medicinal chemistry. 3rd ed. 2005, MyiLibrary
- Merck index. 14th ed. 2006, CambridgeSoft
- Microbial contamination control in the pharmaceutical industry 2004, CRCnetBASE
- Microbiological contamination control in pharmaceutical clean rooms 2004, CRCnetBASE
- Microencapsulation. 2nd ed. 2006, CRCnetBASE
- Modern pharmaceutics. 4th ed., rev. and expanded. 2002, CRCnetBASE
- Modified-release drug delivery technology 2003, CRCnetBASE
- Harrison's Principles of Internal Medicine
- AAP Red Book Online
- Robbins & Cotran Pathologic Basis of Disease
- Sabiston Textbook of Surgery
- Nelson's Textbook of Pediatrics
- Surgical Exposures in Orthopaedics
- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
- Red Book Online
- ICU Book
- Primary Care Medicine
- Campbell-Walsh Urology
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