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Pathology and Laboratory Medicine

  • 2011 Springer
    Bostwick, David G.; Cheng, Liang.
    Part 1. General Pathology -- Cytopathology / Fadi W. Abdul-Karim, Jennifer Brainard and Claire W. Michael -- Immunohistochemical Diagnosis in Surgical Pathology / Nancy Klipfel, Raul Simental-Pizarro and Clive R. Taylor -- Tumors of Unknown Primary / Nancy Klipfel, Raul Simental-Pizarro and Clive R. Taylor -- Diagnostic Electron Microscopy / Jean L. Olson -- Transplantation Pathology / Oscar W. Cummings -- Microbiology for the Surgical Pathologist / Deborah E. Blue and Stephen D. Allen -- Forensic Pathology / Frank P. Miller and Jeffrey J. Barnard -- Autopsy / Dean Hawley -- Biomedical Informatics for Anatomic Pathology / Waqas Amin, Uma Chandran, Anil V. Parwani and Michael J. Becich -- Quality Assurance and Regulations for Anatomic Pathology / Maxwell L. Smith and Stephen S. Raab -- Molecular Diagnostic Pathology / James Huang and Richard D. Press -- Molecular Pathology of Solid Tumors / Franklin R. Moore and Richard D. Press -- Human Genetic Disorders / Teresa M. Kruisselbrink, Noralane M. Lindor, Elyse B. Mitchell, Brittany C. Thomas and Cassandra K. Runke, et al. -- Part 2. Organ Systems -- Neuropathology / Eyas M. Hattab, Matthew C. Hagen, Bernd W. Scheithauer and Arie Perry -- Lymph Node / Ellen D. McPhail and Paul J. Kurtin -- Spleen / Dennis P. O'Malley and Attilio Orazi -- Bone Marrow / Dennis P. O'Malley -- Neoplasms of the Skin and Immunodermatology / Daniel P. Vandersteen, Melanie Triffet-Treviño and Chris H. Jokinen -- Nonneoplastic Skin Diseases / Steven D. Billings and Antoinette F. Hood -- Endocrine Pathology / Lori A. Erickson -- Bone and Joints / Jasvir S. Khurana and Guldeep Uppal -- Soft Tissue Tumors / Leona A. Doyle and Alessandra F. Nascimento -- Tumor of the Salivary Glands / Diana M. Bell and Adel K. El-Naggar -- Head and Neck / John D. Henley and Don-John Summerlin -- Eye and Ocular Adnexae / Jose M. Bonnin -- Mediastinum and Thymus / Chung-Che (Jeff) Chang, Munir Shahjahan and Joseph F. Tomashefski -- Cardiovascular Pathology / Eric A. Pfeifer -- Lung and Pleura / Carol F. Farver and Andrea V. Arrossi -- Breast / Mohiedean Ghofrani and Fattaneh A. Tavassoli -- Vulva and Vagina / Sharon X. Liang and Wenxin Zheng -- Uterus and Fallopian Tube / Maritza Martel and Fattaneh A. Tavassoli -- Ovary and Peritoneum / Robert E. Emerson -- Placenta and Gestational Trophoblastic Disease / Raymond W. Redline -- Nonneoplastic Renal Diseases / Geoffrey A. Talmon and Donna J. Lager -- Tumors of the Kidney / Gregory T. MacLennan and Liang Cheng -- Urinary Bladder / Liang Cheng, Antonio Lopez-Beltran and David G. Bostwick -- Renal Pelvis, Ureter, and Urethra / Antonio Lopez-Beltran, Sean R. Williamson and Liang Cheng -- Prostate / David G. Bostwick and Liang Cheng -- Testis and Testicular Adnexa / Kenneth A. Iczkowski and Thomas M. Ulbright -- The Penis / Alcides Chaux, Gustavo Ayala and Antonio L. Cubilla -- Esophagus and Stomach / Thomas P. Plesec and John R. Goldblum -- Small Intestine, Appendix, Colorectum, and Anus / Stephen C. Lawhorn and Shuan C. Li -- Pancreas / Olca Basturk and N. Volkan Adsay -- Nonneoplastic Hepatobiliary Disease / Romil Saxena -- Neoplasms of the Liver and Biliary System / Romil Saxena.
  • v. 3, 2006. Springer
    Rutty, Guy N.
    v. 1. No individual title -- v. 2. Recent advances, topics, and developments -- v. 3. Current methods and modern trends (2006).
  • 2014 Springer
    Rutty, Guy N.
    This book covers new and exciting topics which have emerged in the area of autopsy recently, including the three different post-mortem CT-angiography systems currently available to practitioners in this field; a highly topical chapter on the role of genetic abnormalities in the handling of drugs within the body and how this can affect the interpretation of toxicological results in relation to how the drug may have caused or contributed to death; an update on the current classification and considerations related to deaths due to hanging; a review of injuries and fatalities caused by animals including post-mortem scavenging; an authoritative review of poisons and toxins from water and the life that inhabits it; and recent advances in knowledge in the use of entomology as an investigative tool as well as knowledge related to colonisation of cadavers by insects, animals and birds. Essentials of Autopsy Practice: Advances, Updates and Emerging Technologies is a multi-subject book, aimed at different grades of practitioners, from different practice areas, covering topics that are currently discussed and anticipated to be discussed in the field of autopsy practice over the next few years.
  • 2008 Springer
    Rutty, Guy N.
    Postmorten toxicological redistribution -- Examination of fractures at autopsy -- The relationship of body weight and sudden death -- Fatal sexual abuse in childhood -- Elder abuse and gerontocide -- Air crash investigation for histopathologists -- Bioterrorism -- The chronological dating of injury.
  • 2013 Springer
    Zhao, Robert Chunhua.
    Basic Research/Mechanisms -- A Historical Overview and Concepts of Mesenchymal Stem Cells / Shihua Wang, Robert Chunhua Zhao -- Biology of MSCs Isolated from Different Tissues / Simone Pacini -- Secretome of Mesenchymal Stem Cells / Yuan Xiao ... [et al.] -- Immunomodulatory Properties of Mesenchymal Stem Cells and Related Applications / Lianming Liao, Robert Chunhua Zhao -- Mesenchymal Stem Cell Homing to Injured Tissues / Yaojiong Wu, Robert Chunhua Zhao -- Major Signaling Pathways Regulating the Proliferation and Differentiation of Mesenchymal Stem Cells / Joseph D. Lamplot ... [et al.] -- MicroRNAs in Mesenchymal Stem Cells / Mohammad T. Elnakish, Ibrahim A. Alhaider, Mahmood Khan -- Genetic Modification of MSCs for Pharmacological Screening / Jie Qin, Martin Zenke -- Control of Mesenchymal Stem Cells with Biomaterials / Sandeep M. Nalluri, Michael J. Hill, Debanjan Sarkar -- Clinical Translation -- Mesenchymal Stem Cells for Cardiovascular Disease / Wei Wu, Shuyang Zhang -- Mesenchymal Stem Cells as Therapy for Graft Versus Host Disease: What Have We Learned? / Partow Kebriaei ... [et al.] -- Mesenchymal Stem Cells for Liver Disease / Feng-chun Zhang -- Mesenchymal Stem Cells for Bone Repair / Hongwei Ouyang, Xiaohui Zou, Boon Chin Heng, Weiliang Shen -- Mesenchymal Stem Cells for Diabetes and Related Complications / Vladislav Volarevic, Majlinda Lako, Miodrag Stojkovic -- Mesenchymal Stromal Cell (MSC) Therapy for Crohn's Disease / Jignesh Dalal -- The Summary of Stroke and Its Stem Cell Therapy / Renzhi Wang ... [et al.] -- Mesenchymal Stem Cell Transplantation for Systemic Lupus Erythematosus / Lingyun Sun -- International Regulations and Guidelines Governing Stem Cell Based Products -- Considerations of Quality Control Issues for the Mesenchymal Stem Cells-Based Medicinal Products / Bao-Zhu Yuan ... [et al.] -- Regulations/Ethical Guidelines on Human Adult/Mesenchymal Stem Cell Clinical Trial and Clinical Translation / Xiaomei Zhai, Renzong Qiu.
  • 2011 Springer
    Marchevsky, Alberto M.; Wick, Mark R.
    Introduction to Evidence-Based Pathology and Laboratory Medicine -- Evidence-Based Pathology: A Stable Set of Principles for a Rapidly Evolving Specialty -- What Is Best Evidence in Pathology? -- Biostatistics 101 -- Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative Model -- Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem Cases -- Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study Results -- Power Analysis and Sample Sizes in Pathology Research -- Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies -- Decision Analysis and Decision Support Systems in Anatomic Pathology -- Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience -- Evidence-Based Cell Pathology Revisited: A Personal View -- Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical Cen -- Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based Approach -- Meta-Analysis 101 for Pathologists -- Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-Purposes -- Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into Practice -- The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory Evidence -- Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support Systems -- Evidence-Based Pathology and Tort Law: How Do They Compare?
  • 2013 Springer
    Malek, Anastasia.
    Metastatic dissemination of cancer is a main cause of cancer related deaths, therefore biological mechanisms implicated in metastatic process presents an essential object of cancer research. This research requires creation and utilization of adequate laboratory models. The book describes main approaches to model processes of metastatic cancer dissemination and metastases development. The book is structured in according with various metastatic pathways reflecting molecular specificity of metastatic process as well as anatomical specificity of aria of dissemination.
  • 2010 Springer
    Mader, I.; Fürst-Weger, P.; Mader, R.; Nogler-Semenitz, E.; Wassertheurer, S.
  • 2015 Springer
    Grossniklaus, Hans E.; Heegaard, Steffen.
    This book is a comprehensive, in-depth, and up-to-date resource on eye pathology that will be of great practical value for ophthalmic and general pathologists and ophthalmologists. Congenital abnormalities, inflammatory conditions, infections, injuries, degenerative diseases, and tumors are all covered with the aid of more than 700 images. In the case of tumors, the wide variety of neoplasms that occur in the eyelid, conjunctiva, retina, uveal tract, lacrimal gland and sac, orbit, and optic nerve are comprehensively reviewed, and the most recent knowledge on the relation between genetics and prognosis is presented. Entries on specific diseases are organized in a standard way, with information on etiology, epidemiology, clinical presentation, pathological characteristics, differential diagnosis, therapy, and prognosis. The authors are all recognized experts and members of the European and American ophthalmic pathology societies.
  • 2010 Springer
    Altarescu, Gheona; Beck, Michael; Elstein, Deborah.
  • 2006 NCBI Bookshelf
    Beck, Michael; Mehta, Atul B.; Sunder-Plassmann, Gere.
  • 2015 ClinicalKey
    Ferri, Fred F.
    For nearly 25 years, Ferri's concise, pocket-sized resources have served as the go-to medical reference books among students, residents, and other medical professionals. Ferri's Best Test continues that trend, providing fast, effective, and efficient guidance and helping you review the most important laboratory and imaging testing information, with an added focus on cost-effective decision making. Quickly access important information with concise, well-organized guidance to the most common lab tests and diagnostic imaging modalities.Simplify your decision-making process through analysis that describes the most common imaging studies for each organ system, reviewing their indications, advantages, disadvantages, and approximate costs. Confidently address problematic situations with background data that examines over 384 laboratory tests, describing the normal range of results in adult patients, typical abnormalities (positive tests, increased or decreased values), and the likeliest causes. Select the best test for diagnosing more than 200 common diseases and disorders. Keep important information at your fingertips with this portable, pocket-sized format that allows for convenient consultation anytime, anywhere.
  • 2007 Springer
    Keeling, Jean; Khong, T. Yee.
  • 2005 Springer Protocols
    Brenner, David; Phan, Sem Hin; Varga, John.
    Also available: Print – 2005
  • 2013 Springer
    Tse, Gary M.; Schmitt, Fernando; Tan, Puay Hoon.
    This book provides a detailed update on all aspects of fine-needle aspiration cytology of breast lesions. It will serve readers as an up-to-date reference and atlas on both new entities in breast pathology, including borderline lesions such as flat epithelial atypia, and the classic benign and malignant lesions. Throughout, emphasis is placed on the characteristic diagnostic features as well as the common pitfalls faced by cytologists. As cytologic features can be highly variable, corresponding cytology and histology images are displayed together, enabling readers to gain a good understanding of the morphologic features of various lesions. Core-needle biopsy and fine-needle aspiration cytology are compared in depth, with attention to their relative strengths and weaknesses and indications. In addition, the impact of molecular classification of breast cancers on cytologic diagnosis is explored, and the use of molecular techniques in diagnostic cytology is discussed.
  • 2009 Karger
    Åkerman, Måns; Domanski, Henryk A.; Jonsson, Kjell.
    Epidemiology of bone tumours -- Radiological investigation of bone tumours -- Morphological diagnosis of bone tumours -- Cytology of normal constituents in bone aspirates and of reactive changes -- Cytological features of bone tumours in FNA smears I : osteogenic tumours -- Cytological features of bone tumours in FNA smears II : cartilaginous tumours -- Cytological features of bone tumours in FNA smears III : Ewing family tumours -- Cytological features of bone tumours in FNA smears IV : notochordal tumours -- Cytological features of bone tumours in FNA smears V : giant-cell lesions -- Rare targets for FNAC and diagnostic problems with benign tumours/lesions with variable numbers of osteoclast-like giant cells -- Lymphohaematopoetic and histiocytic tumours -- Inflammatory lesions -- Bone metastases -- Fine needle aspiration as the first diagnostic modality for spinal and sacral lesions.
  • 2009 Karger
    Skoog, Lambert; Porwit, Anja; Tani, Edneia.
    Historical aspects -- Techniques -- Flow cytometry in fine-needle aspiration diagnosis of lymphomas / in collaboration with Anna Porwit-MacDonald -- B cell neoplasms -- T cell neoplasms -- Hodgkin lymphoma -- Lymphadenopathy in HIV-infected patients -- Histiocytic and dendritic neoplasms -- Extranodal lymphomas -- Lymphoma look-alike.
    Also available: Print – 2009
  • 2011 Springer
    Dettmeyer, Reinhard.
    Introduction -- Staining Techniques and Microscopy -- Histopathology of Selected Trauma -- Histopathology and Drug Abuse -- Toxin- and Drug-Induced Pathologies -- Alcohol-Related Histopathology -- Heat, Fire, Electricity, Lightning, Radiation, and Gases -- Hypothermia -- Thrombosis and Embolism -- Vitality, Injury Age, Determination of Skin Wound Age, and Fracture Age -- Aspiration and Inhalation -- Forensic-Histological Diagnosis of Species, Gender, Age, and Identity -- Coronary Sclerosis, Myocardial Infarction, Myocarditis, Cardiomyopathy, Coronary Anomalies, and the Cardiac Conduction System -- Vascular, Cardiac Valve, and Metabolic Diseases -- Lethal Infections, Sepsis, and Shock -- Endocrine Organs -- Pregnancy-Related Death, Death in Newborns, and Sudden Infant Death Syndrome -- Forensic Cytology -- Histothanatology: Autolysis, Putrefaction, Mummification -- Forensic Neuropathology.
  • 2007 CRCnetBASE
    Black, Sue M.; Thompson, Timothy James Upton.
    section 1. Identification from biomolecular evidence -- section 2. Identification from latent prints -- section 3. Identification from the soft tissues -- section 4. Identification from the hard tissues -- section 5. Facial identification -- section 6. Identification from methods of communication -- section 7. Identification from podiatry and walking -- section 8. Identification from personal effects -- section 9. The Context of forensic human identification -- section 10. Forensic human identification case studies.
  • 2011 Springer Protocols
    Al-Mulla, Fahd.
    Regulatory and ethical Issues on the utilization of FFPE tissues in research / Catherine M. With, David L. Evers, and Jeffrey T. Mason -- Tissue microarrays : construction and uses / Carol B. Fowler ... [et al.] -- Standardization in immunohistology / Anthony S.-Y. Leong and Trishe Y.-M. Leong -- Multiple immunofluorescence labeling of formalin-fixed paraffin-embedded tissue / David Robertson and Clare M. Isacke -- Microwaves for chromogenic In situ hybridization / Anthony S.-Y. Leong and Zenobia Haffajee -- Automated analysis of FISH-stained HER2/neu samples with metafer / Christian Schunck and Eiman Mohammad -- Laser capture microdissection of FFPE tissue sections bridging the gap between microscopy and molecular analysis / Renate Burgemeister -- Nucleic acids extraction from laser microdissected FFPE tissue sections / Renate Burgemeister -- Microarray-based CGH and copy number analysis of FFPE samples / Fahd Al-Mulla -- Microarray profiling of DNA extracted from FFPE tissues using SNP 6.0 affymetrix platform / Marianne Tuefferd ... [et al.] -- Whole genome amplification of DNA extracted from FFPE tissues / Mira Bosso and Fahd Al-Mulla -- Pyrosequencing of DNA extracted from formalin-fixed paraffin-embedded tissue / Brendan Doyle, Ciaran O'Riain, and Kim Appleton -- Analysis of DNA methylation in FFPE tissues using the methylight technology / Ashraf Dallol ... [et al.] -- RT-PCR gene expression profiling of RNA from paraffin-embedded tissues prepared using a range of different fixatives and conditions / Mei-Lan Liu ... [et al.] -- RT-PCR-based gene expression profiling for cancer biomarker discovery from fixed, paraffin-embedded tissues / Aaron Scott ... [et al.] -- MicroRNA isolation from formalin-fixed, paraffin-embedded tissues / Aihua Liu and Xiaowei Xu -- Gene expression profiling of RNA extracted from FFPE tissues : NuGEN technologies' whole-transcriptome amplification system / Leah Turner, Joe Don Heath, and Nurith Kurn -- Protein mass spectrometry applications on FFPE tissue sections / Carol B. Fowler, Timothy J. O'Leary, and Jeffrey T. Mason -- Alternative fixative to formalin fixation for molecular applications : the RCL2®-CS100 approach / Amelie Denouel ... [et al.].
  • v. 1-, 2009- Springer
    Cagle, Philip T.
  • 2012 Springer
    Mohsin, Syed K.
    1. Sentinel Lymph Nodes -- 2. Assessment of the Surgical Margins -- 3. Diagnostic Evaluation of a Breast Mass -- 4. Handling of Specimens with a Nonpalpable Lesion -- 5. Core Needle Biopsies -- 6. Regulatory Requirements for Breast Specimens.
  • 2009 Springer
    Ro, Jae Y.; Shen, Steven S.; Truong, Luan D.
  • 2009 Springer
    Allen, Timothy C.; Cagle, Philip T.
  • 2012 Springer
    Dunphy, Cherie H.
  • 2010 Springer
    Allen, Timothy C.; Cagle, Philip T.
  • 2012 Thieme Book
    Steffers, Gabriele; Credner, Susanne.
  • 2012 Springer
    Green, Jeff; Ried, Thomas.
    Overview of designing genetically engineered mouse (GEM) models -- Use of Cre-loxP technology and inducible systems to generate mouse models of cancer -- Using recombineering technology to create genetically engineered mouse models -- Insertional mutagenesis for generating mouse models of cancer -- RCAS/TVA somatic gene transfer method in modeling human cancer -- Target-selected ENU mutagenesis to develop cancer models in the rat -- Tumor pathology of genetically engineered mice: genomic pathology -- Genomic DNA copy number alterations in mouse cancer models and human cancer -- Characterization of chromosomal translocations in mouse models of hematological malignancies using spectral karyotyping, FISH, and immunocytochemistry -- Expression profiling of mouse models of human cancer: model categorization and guidance for preclinical testing -- Imaging mouse models of human cancer -- Identifying mammary epithelial stem and progenitor cells -- Differentiation programs in development and cancer -- Roles of p53 and pRB tumor suppressor networks in human cancer: insight from studies in the engineered mouse -- Mouse models for colorectal cancer -- Src family tyrosine kinases: implications for mammary tumor progression -- Maspin and suppresion of tumor metastasis -- Epigenetic mouse models -- Modeling transforming growth factor-ss signalling in cancer -- Modeling stromal-epithelial interactions -- Utilizing mouse models of human cancer for assessing immune modulation of cancer development -- Transplanted tumor models for preclinical drug testing and the potential benefit of genetically engineered mouse models -- Development and use of genetically tractable preclinical mouse models -- Animal models for breast cancer prevention research -- Oncogene addiction: mouse models and clinical relevance for molecularly targeted therapies -- Mouse models in preclinical drug development: applications to CNS models -- Mouse models of human cancer: role in preclinical testing and personalized medicine -- Mighty, bow how useful? The emerging role of genetically engineered mice in cancer drug discovery and development.
  • 2015 Springer
    Magi-Galluzzi, Cristina; Przybycin, Christopher G.
    This book provides a comprehensive, state-of-the art review of the genitourinary tumor pathology field and the most contemporary insights regarding specimen submission, histologic morphology, immunohistochemistry, and molecular studies useful in the diagnosis of genitourinary neoplasms. Discussion of the clinical implications of pathological findings is contributed by renowned clinicians in the field. This handsome volume guides the reader through the intricacies of genitourinary tumor pathology, diagnosis, reporting, and prognosis. Written by experts in the field, Genitourinary Pathology: Practical Advances is of great value to anatomic pathologists, urologists, fellows in genitourinary pathology, as well as upper level residents training in pathology .
  • 2015 ClinicalKey
    Magi-Galluzzi, Cristina; Zhou, Ming.
    Nonneoplastic diseases of the prostate / Kiril Trpkov -- Neoplastic diseases of the prostate / Ming Zhou, Cristina Magi-Galluzzi -- Nonneoplastic diseases of the urinary bladder / Fang-Ming Deng, Jonathan Melamed -- Neoplasms of the urinary bladder / Jesse K. McKenney, Ming Zhou, Cristina Magi-Galluzzi -- Nonneoplastic diseases of the kidney / Stephen M. Bonsib -- Neoplasms of the kidney / Ming Zhou, Eyas M. Hattab, John N. Eble, Liang Cheng -- Introduction to renal biopsy / Laura Barisoni, Lois J. Arend, David B. Thomas -- Diseases of the ureter and renal pelvis / Ximing J. Yang -- Diseases of penis, urethra, and scrotum / Rajal B. Shah -- Nonneoplastic diseases of the testis / Cristina Magi-Galluzzi, Howard S. Levin -- Neoplasms of the testis / Charles C. Guo.
  • 2007 ClinicalKey
    Magi-Galluzzi, Cristina; Zhou, Ming.
    This volume in the Foundations in Diagnostic Pathology Series packs today's most essential genitourinary pathology know-how into a compact, high-yield format! Its pragmatic, well-organized approach, abundant full-color illustrations, and at-a-glance tables make the information you need easy to access. It covers both neoplastic and non-neoplastic diseases of the genitourinary system. Reviews normal histology before examining abnormal findings. Covers all of the most commonly seen neoplastic and non-neoplastic conditions of the genitourinary system. Uses a consistent, user-friendly format to explore each entity's clinical features pathologic features (gross and microscopic) ancillary studies differential diagnoses and prognostic and therapeutic considerations. Offers hundreds of full-color illustrations that demonstrate the key features of a wide variety of pathologic lesions.
  • 2015 Springer
    Netto, George J.; Schrijver, Iris.
    Genomic Applications in Pathology provides a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays are discussed together with issues related to reporting, including the pathologist?s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms are detailed, as well as genomic applications in pharmacogenomics, inherited genetic diseases, and infectious diseases. The latest iteration of practice recommendations and guidelines in genomic testing, put forth by stakeholder professional organizations such as the Association for Molecular Pathology and the College of American Pathologists, are also discussed in the volume, as well as regulatory issues and laboratory accreditation related to genomic testing. Written by experts in the field, Genomic Applications in Pathology provides a comprehensive resource that is of great value to practicing molecular pathologists, hematopathologists, other subspecialized pathologists, general pathologists, pathology trainees, oncologists, and geneticists.
  • 2015 Springer
    Tambouret, Rosemary H.; Wilbur, David C.
    This volume provides a compact, concise and up-to-date resource for pathologists and clinicians who are involved in women's health. The book summarizes the incidence, epidemiology and risk factors for cervical adenocarcinoma, while reviewing the normal histology of the cervix and glandular lesions of the cervix. The cytological appearance of glandular lesions of the cervix and their mimics is amply illustrated and discussed. Management of glandular lesions is also outlined. Written by authorities in the field, Glandular Lesions of the Uterine Cervix: Cytopathology with Histologic Correlates is of great value to cytopathologists, surgical pathologists, gynecologic oncologists and surgeons.
  • 2002 CRCnetBASE
    Gu, Jiang; Hacker, Gerhard W.
    1. Silver Stains for the Identification of Neuroendocrine Cell Types / L. Grimelius -- 2. Autometallographic Tracing of Gold, Silver, Bismuth, Mercury, and Zinc / G. Danscher, G. W. Hacker, and M. Stoltenberg -- 3. Silver- and Gold-Based Autometallography of Nanogold / J.E Hainfeld and R.D. Powell -- 4. Immunogold-Silver Staining for Light Microscopy Using Colloidal or Clustered Gold (Nanogold) / G.W. Hacker, A.L.M. Cheung, R.R. Tubbs, L. Grimelius, G. Danscher, and C. Hauser-Kronberger -- 5. The Protein A-Gold-Silver Staining Method / O. Fujimori -- 6. Microscopic Uses of Nanogold® / J.E Hainfeld, R.D. Powell, and FR. Furuya -- 7. Combined Fluorescent and Gold Probes for Microscopic and Morphological Investigations / R.D. Powell and J. Hainfeld -- 8. Detection of Human Papillomavirus by In Situ Hybridization Using an In Situ PCR Thermal Cycler / P. Jackson and F.A. Lewis -- 9. Supersensitive In Situ Hybridization by Tyramide Signal Amplification and Nanogold® Silver Staining: The Contribution of Autometallography and Catalyzed Reporter Deposition to the Rejuvenation of In Situ Hybridization / R.R. Tubbs, J. Pettay, T. Grogan, A.L.M. Cheung, R.D. Powell, J. Hainfeld, C. Hauser-Kronberger, and G.W. Hacker -- 10. Immunogold Labeling Techniques for Transmission Electron Microscopy: Applications in Cell and Molecular Biology / L. Lossi, P Aimar, E. Beltramo, and A. Merighi -- 11. Pre-Embedding Immunoelectron Microscopy with Nanogold® Immunolabeling, Silver Enhancement, and Its Stabilization by Gold / H. Sawada and M. Esaki -- 12. Gold Cluster Immunoprobes: Light and Electron Microscopy / J.M. Robinson, T. Takizawa, and D.D. Vandré -- 13. Highly Sensitive Ultrastructural Immunogold Detection Using Tyramide and Gold Enhancement / C. Schöfer and K. Weipoltshammer -- 14. In Situ Hybridization at the Electron Microscopic Level / C. Schöfer and K. Weipoltshammer -- 15. Immunogold-Silver Staining for Scanning Electron Microscopy in Cancer Research / B.-L. Wang, N. Flay, and G.W. Hacker -- 16. Immunogold-Silver Scanning Electron Microscopy Using Glycerol Liquid Substitution / J. Šamaj, H.-J. Ensikat, W. Barthlott, and D. Volkmann.
  • 2005 Springer
    Seiler, J. P.
  • 2005 Springer
    Corley, Ronald B.
    1. Detection and analysis of proteins -- 2. Detection and analysis of nucleic acids -- 3. Recombinant DNA techniques: cloning and manipulation of DNA -- 4. Antibody-based techniques -- 5. Microscopy: imaging of biological specimens -- 6. The derivation and manipulation of experimental animals in biomedical sciences.
  • 2008 Springer
    Adams, Vernard Irvine.
    Autopsy protocol -- Opinion reports -- Other reports -- Style -- Death certification -- Record retention.
  • 2009 Springer
    Waters, Brenda L.
    Autopsy techniques and procedures -- Ensuring quality in the hospital autopsy -- Principles of dissection -- Cardiovascular system -- Nervous system -- Eye and adnexa -- Autopsy laboratory -- Autopsy microbiology -- Autopsy chemistry -- Chromosome analysis of autopsy tissue -- Postmortem imaging techniques -- Autopsies of bodies containing radioactive materials -- The hospital autopsy report, death certification -- Medicolegal autopsy and postmortem toxicology -- Legal aspects of autopsy practice -- Fixation and transport of autopsy material -- Museum techniques.
  • 2008 Ovid
    Corwin, Elizabeth J.
  • 2011 Ovid
    Lazenby, Ramona Browder.
    "This pathophysiology handbook is ideally suited for easy reference in the classroom or clinical environment. The book presents a summary of physiology concepts for each body system, followed by an overview of important pathophysiology concepts related to 'alterations' in that body system. These pathophysiology concepts provide the necessary foundation for understanding the disease or injury states that are presented next in the chapter"--Provided by publisher.
  • 2005 Springer
    Gilbert-Barness, Enid; Debich-Spicer, Diane E.; Opitz, John M.
    General principles -- Pediatric autopsy: fetus, newborn, and child -- Examination of the human embryo -- The placenta -- Hydrops -- Chromosomal defects -- Congenital abnormalities -- Cardiovascular system -- Respiratory system -- Gastrointestinal system -- Liver, gallbladder, biliary tract, and pancreas -- Renal system -- Male and female genitourinary systems -- Central nervous system -- Thymus, spleen, lymph nodes, and immunodeficiency -- Skeletal system -- The eye and adnexa sectioning -- Metabolic diseases -- Sudden infant death -- Pediatric forensic pathology -- Special procedures -- Infection control and biological hazards in the autopsy.
    Also available: Print – 2005
  • 2014 Springer
    Gilbert-Barness, Enid; Debich-Spicer, Diane E.; Steffensen, Thora S.
    Pathologists have long recognized that pediatric autopsy requires great care in technique and dissection to ensure that easily overlooked malformations are recognized and accurate diagnoses are made. The highly experienced authors have created a new edition of Handbook of Pediatric Autopsy Pathology, a comprehensive reference guide to the actual performance of the pediatric autopsy and the optimal recognition and interpretation of pathologic findings. The Handbook of Pediatric Autopsy Pathology, Second Edition covers the spectrum of pediatric pathology with particular reference to those conditions that can be identified at autopsy. New and updated material includes microbiological studies, particularly with the advent of newly described micro-organisms causing disease. The volume also addresses new developments in metabolic diseases, new techniques of ultrasound imaging, and specialized laboratory testing. Furthermore, the book provides a wealth of practical information and bibliographic citations throughout, new copious illustrations and line drawings, numerous standard reference tables, and appendices at the end of multiple chapters. Authored by authorities in the field, Handbook of Pediatric Autopsy Pathology, Second Edition is a valuable resource that will assist general and pediatric pathologists, neonatologists, interns and residents in training, as well as specialists in cytogenetics and ultrasound technicians in understanding the manner and cause of death in its broadest and comprehensive sense.
  • 2013 ScienceDirect
    2013 ClinicalKey
    Bolon, Brad; Haschek, Wanda M.; Mahler, Beth W.; Ochoa, Ricardo; Rousseaux, Colin George; Wallig, Matthew A.
  • 2013 ScienceDirect
    2013 ClinicalKey
    Thompson, Lester D. R.
    "Part of the popular Foundations in Diagnostic Pathology Series, Head and Neck Pathology delivers vital diagnostic guidance in a compact, high-yield format. Concise and easy to use, this pathology reference offers a practical, well-organized approach to evaluating a wide range of specimens in both head and neck and related endocrine pathology. Easily review normal histology before examining abnormal findings so you can avoid false positives. Reach accurate diagnostic conclusions easily with a consistent, user-friendly format that explores each entity's clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnoses, and prognostic and therapeutic considerations. Apply the latest diagnostic criteria for all of the most commonly seen neoplastic and non-neoplastic conditions of the larynx, hypopharynx, and trachea; nasal cavity, paranasal sinuses, and nasopharynx; oral cavity and oropharynx; salivary glands; ear; and temporal bone. Gain a superb visual understanding of important histologic features with hundreds of full-color illustrations representing a wide variety of pathologic lesions. Quickly reference key information with convenient, at-a-glance clinical and pathologic boxes throughout."--Summary of the editor.
  • 2013 ClinicalKey
    Aster, Jon C.; Kutok, Jeffrey L.; Pozdnyakova, Olga.
  • 2008 ScienceDirect
    Naeim, Faramarz; Grody, Wayne W.; Rao, P. Nagesh.
  • 2011 ClinicalKey
    Jaffe, Elaine Sarkin.
    Pt. 1. Technical aspects: Processing of the lymph node biopsy specimen -- Fine-needle aspiration of lymph nodes -- Collection, processing, and examination of bone marrow specimens -- Immunohistochemistry for the hematopathology laboratory -- Flow cytometry -- Molecular diagnosis in hematopathology -- Cytogenetic analysis and related techniques in hematopathology -- Pt. 2. Normal and reactive conditions of hematopoietic tissues -- Normal lymphoid organs and tissues -- The reactive lymphadenopathies -- The normal bone marrow -- Evaluation of anemia, leukopenia, and thrombocytopenia -- Bone marrow findings in inflammatory, infectious, and metabolic disorders -- Pt. 3. Lymphoid neoplasms -- Principles of classification of lymphoid neoplasms -- section 1. Mature B-cell neoplasms -- Mature B-cell neoplasms: chronic lymphpcytic leukemia-small lymphocytic lymphoma, B-cell prolymphocytic leukemia, and lymphoplasmacytic lymphoma -- Hairy cell leukemia -- Splenic marginal zone lymphoma -- Follicular lymphoma -- Extranodal marginal zone lymphoma: MALT lymphoma -- Primary cutaneous B-cell lymphoma -- Nodal marginal zone lymphoma -- Mantle cell lymphoma -- Diffuse large B-cell lymphoma -- Lymphomatoid granulomatosis -- Burkitt's lymphoma -- Plasma cell neoplasms -- Nodular lymphocyte-predominant type of Hodgkin's lymphoma -- Classical Hodgkin's lymphoma -- section 2. Mature T-cell and NK-cell neoplasms -- NK-cell neoplasms -- Epstein-Barr virus - positive systemic T-lymphoproliferative disorders and related lymphoproliferations of childhood -- T-cell large granular lymphocytic leukemia -- T-cell prolymphocytic leukemia -- Adult T-cell leukemia/lymphoma -- Hepatosplenic T-cell lymphoma -- Peripheral T-cell lymphoma, not otherwise specified -- Angioimmunoblastic T-cell lymphoma -- Anaplastic large cell lymphoma, ALK positive and ALK negative -- Enteropathy-associated T-cell lymphoma and other primary intestinal T-cell lymphomas -- Mycosis fungoides and Sezary syndrome -- Primary cutaneous CD30-positive T-cell lymphoproliferative disorders-- Primary cutaneous T-cell lymphomas: rare subtypes -- section 3. Precursor B- and T-cell neoplasms -- Precursor B- and T-cell neoplasms -- Acute leukemias of ambiguous lineage -- Pt. 4. Myeloid neoplasms -- Principles of classification of myeloid neoplasms -- The myelodysplastic syndromes -- Acute myeloid leukemia -- Myeloproliferative neoplasms -- Myelodysplastic/Myeloproliferative neoplasms -- Mastocytosis -- Eosinophilia and chronic eosinophilic leukemia, including myeloid/lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 -- Blastic plasmacytoid dendritic cell neoplasm -- Pt. 5. Histiocytic proliferations -- Nonneoplastic histiocytic proliferations of lymph nodes and bone marrow -- Langerhans cell histiocytosis and Langerhans cell sarcoma -- Other histiocytic and dendritic cell neoplasms -- Pt. 6. Immunodeficiency disorders -- The pathology of primary immunodeficiencies -- Iatrogenic immunodeficiency-associated lymphoproliferative disorders -- Hematopathology of Human Immunodeficiency Virus (HIV) infection -- Pt. 7. Site-specific issues in the diagnosis of lymphoma and leukemia -- Bone marrow evaluation for lymphoma -- Evaluation of the bone marrow after therapy -- Nonhematopoietic neoplasms of the bone marrow -- Nonlymphoid lesions of the lymph nodes -- Spleen: normal architecture and neoplastic and nonneoplastic lesions -- Diagnosis of lymphoma in extranodal sites other than skin -- Appendix: Staining techniques.
  • 2003 Springer Protocols
    Nagel, R. L.
    Hemoglobin and hemoglobinologists. Preface / R.L. Nagel -- Solubility measurement of the sickle polymer / M.E. Fabry [and others] -- Nuclear magnetic resonance of hemoglobins / J.A. Lukin and C. Ho -- Recombinant single globin-chain expression and purification / K. Adachi -- Transgenic mice and hemoglobinopathies / M.E. Fabry [and others] -- Beta-globin-like gene cluster haplotypes in hemoglobinopathies / S. Muralitharan, R. Krishnamoorthy and R.L. Nagel -- Semisynthesis of hemoglobin / S.A. Acharya and S. Srinivasulu -- Nucleation and crystal growth of hemoglobins. The case of HbC / P.G. Vekilov, A. Feeling-Taylor and R.E. Hirsch -- Hemoglobin fluorescence / R.E. Hirsch -- Methods for analysis of prenatal diagnosis / J.M. Old -- DNA diagnosis of hemoglobin mutations / J.M. Old -- Electrophoretic methods for study of hemoglobins / H. Wajcman -- Measurement of rate constants for reactions of O2, CO, and NO with hemoglobin / J.S. Olson [and others] -- Oxygen equilibrium measurements of human red blood cells / J. Kister and H. Wajcman -- Purification and molecular analysis of hemoglobin by high-performance liquid chromatography / B.N. Manjula and S.A. Acharya -- Analysis of hemoglobins and globin chains by high-performance liquid chromatography / H. Wajcman -- X-ray crystallography of hemoglobins / M.K. Safo and D.J. Abraham.
  • 2011 ClinicalKey
    Henry, John Bernard; McPherson, Richard A.; Pincus, Matthew R.
    Pt. 1. The clinical laboratory. -- General concepts and administrative issues -- Optimizing laboratory workflow and performance -- Pre-analysis -- Analysis: principles of instrumentation -- Analysis: clinical laboratory automation -- Point-of-care and physician office laboratories -- Post-analysis: medical decision-making -- Interpreting laboratory results -- Laboratory statistics -- Quality control -- Clinical laboratory informatics -- Financial management -- Biological, chemical and nuclear terrorism: role of the laboratory -- Pt. 2. Clinical chemistry. -- Evaluation of renal function, water, electrolytes and acid-base balance -- Biochemical markers of bone metabolism -- Carbohydrates -- Lipids and dyslipoproteinemia -- Cardiac injury, atherosclerosis, and thrombotic disease -- Specific proteins -- Clinical enzymology -- Evaluation of liver function -- Laboratory diagnosis of gastrointestinal and pancreatic disorders -- Toxicology and therapeutic drug monitoring -- Evaluation of endocrine function -- Reproductive function and pregnancy -- Vitamins and trace elements -- Chemical basis for analyte assays and common interferences -- Pt. 3. Urine and other body fluids. -- Basic examination of urine -- Cerebrospinal, synovial, and serous body fluids -- Pt. 4. Hematology, coagulation, and transfusion medicine. -- Basic examination of blood and bone marrow -- Hematopoiesis -- Erythrocytic disorders -- Leukocytic disorders -- The flow cytometric evaluation of hematopoietic neoplasia -- Immunohematology -- Transfusion medicine -- Hemapheresis -- Tissue banking and progenitor cells -- Pt. 5. Hemostasis and thrombosis. -- Coagulation and fibrinolysis -- Blood platelets and Von Willebrand Disease -- Laboratory approach to thrombotic risk -- Antithrombotic therapy -- Pt. 6. Immunology and immunopathology. -- Overview of the immune system and immunologic disorders -- Immunoassays and immunochemistry -- Laboratory evaluation of the cellular immune system -- Laboratory evaluation of immunoglobin function and humoral immunity -- Mediators of inflammation: complement, cytokines, and adhesion molecules -- Human leukocyte antigen: the major histocompatibility complex of man -- The major histocompatibility complex and disease -- Immunodeficiency disorders -- Clinical and laboratory evaluation of systemic rheumatic diseases -- Vasculitis -- Organ-specific autoimmune diseases -- Allergic diseases -- Pt. 7. Medical microbiology. -- Viral infections -- Chlamydial, rickettsial, and mycoplasmal infections -- Medical bacteriology -- In vitro testing of antimicrobial agents -- Spirochete infections -- Mycobacteria -- Mycotic diseases -- Medical parasitology -- Specimen collection and handling for diagnosis of infectious diseases -- Pt. 8. Molecular pathology. -- Introduction to molecular pathology -- Molecular diagnostics: basic principles and techniques -- Polymerase chain reaction and other chain reaction amplification technology -- Hybridization array technologies -- Applications of cytogenetics in modern pathology -- Establishing a molecular diagnostics laboratory -- Molecular diagnosis of genetic diseases -- Identity analysis: use of DNA polymorphisms in parentage and forensic testing -- Pharmacogenomics and personalized medicine -- Pt. 9. Clinical pathology of cancer -- Diagnostic and management of cancer using serologic tumor markers -- Oncoproteins and early tumor detection -- Molecular diagnosis of hematopoietic neoplasms -- Molecular genetic pathology of solid tumors -- High-throughput genomic and proteomic technologies in the post-genomic era -- Appendix 1. Physiologic solutions, buffers, acid-base indicators, standard reference materials, and temperature conversions -- Appendix 3. Desirable weights, body surface area, and body mass index (BMI) -- Appendix 1. Approximations of total blood volume (TBV) -- Appendix 4. Periodic table of the elements -- Appendix 5. SI units -- Appendix 6. Common chimeric genes identified in human malignancies -- Appendix 7. Disease/organ panels -- Guidelines for ordering blood for elective surgery
  • 2007
    Henry, John Bernard; McPherson, Richard A.; Pincus, Matthew R.
    Status: Not Checked OutLane Catalog Record
    Blood platelets and Von Willebrand Disease -- Laboratory approach to thrombotic risk -- Antithrombotic therapy -- Overview of the immune system and immunologic disorders -- Immunoassays and immunochemistry -- Laboratory evaluation of the cellular immune system -- Laboratory evaluation of immunoglobin function and humoral immunity -- Mediators of inflammation: complement, cytokines, and adhesion molecules -- Human leukocyte antigen: the major histocompatibility complex of man -- The major histocompatibility complex and disease -- Immunodeficiency disorders -- Clinical and laboratory evaluation of systemic rheumatic diseases -- Vasculitis -- Organ-specific autoimmune diseases -- Allergic diseases -- Viral infections -- Chlamydial, rickettsial, and mycoplasmal infections -- Medical bacteriology -- In vitro testing of antimicrobial agents -- Spirochete infections -- Mycobacteria -- Mycotic diseases -- Medical parasitology -- Molecular pathology of infectious diseases -- Specimen collection and handling for diagnosis of infectious diseases -- Bioterrorism: microbiology -- Introduction to molecular pathology -- Molecular diagnostics: basic principles and techniques -- Polymerase chain reaction and other chain reaction amplification technology -- Hybridization array technologies -- Applications of cytogenetics in modern pathology -- Establishing a molecular diagnostics laboratory -- Molecular diagnosis of hematopoietic neoplasms -- Molecular diagnosis of genetic diseases -- Identity analysis: use of DNA polymorphisms in parentage and forensic testing -- Diagnostic and management of cancer using serologic tumor markers -- Oncoproteins and early tumor detection -- Diagnostic and prognostic impact of high-throughput genomic and proteomic technologies in the post-genomic era. General concepts and administrative issues -- Optimizing laboratory workflow and performance -- Pre-analysis -- Analysis: principles of instrumentation -- Analysis: clinical laboratory automation -- Point-of-care and physician office laboratories -- Post-analysis: medical decision-making -- Interpreting laboratory results -- Laboratory statistics -- Quality control -- Clinical laboratory informatics -- Financial management -- Biological, chemical and nuclear terrorism: role of the laboratory -- Evaluation of renal function, water, electrolytes and acid-base balance -- Biochemical markers of bone metabolism -- Carbohydrates -- Lipids and dyslipoproteinemia -- Evaluation of cardiac injury and function -- Specific proteins -- Clinical enzymology -- Evaluation of liver function -- Laboratory diagnosis of gastrointestinal and pancreatic disorders -- Toxicology and therapeutic drug monitoring -- Evaluation of endocrine function -- Reproductive function and pregnancy -- Vitamins and trace elements -- Basic examination of urine -- Cerebrospinal, synovial, and serous body fluids -- Basic examination of blood and bone marrow -- Hematopoiesis -- Erythrocytic disorders -- Leukocytic disorders -- The flow cytometric evaluation of hematopoietic neoplasia -- Immunohematology -- Transfusion medicine -- Hemapheresis -- Tissue banking and progenitor cells -- Coagulation and fibrinolysis --
  • 2014 Springer Protocols
    Day, Christina E.
  • 2012 ScienceDirect
    Greaves, P.
  • 2014 Springer
    Hellquist, Henrik B.; Skalova, Alena.
    Over the past 25 years it has become more and more evident that salivary gland pathology is by far the subject within head and neck pathology that causes the most diagnostic challenges and problems for general pathologists. Among the reasons for this are the relative rarity of salivary gland tumors (as a result of which the general pathologist does not gain sufficient personal experience in their diagnosis), their striking diversity (there are almost 40 different histological tumor entities), and the fact that some tumours dedifferentiate and some benign tumors progress to become malignant. This book is a comprehensive guide to salivary gland pathology that illustrates almost every type of salivary gland tumor and will assist greatly in routine diagnostic work. Non-neoplastic lesions, benign epithelial tumors, malignant epithelial tumors, and non-epithelial and secondary tumors are all covered in detail, and the WHO and TNM classifications are clearly explained. Another significant feature is the incorporation of important knowledge gained during the past few years regarding the genetics of salivary gland tumors. Histopathology of the Salivary Glands will be of interest not only to pathologists but also to dentists, ENT and head and neck surgeons, and oncologists.
  • 2013 Springer
    Allen, Derek C.; Cameron, R. Iain.
    Covering anatomical, clinical, pathological and laboratory aspects of surgical histopathology specimens, this book relates specimen dissection and its clinical context to relevant histopathology reports, and therefore a more comprehensive patient prognosis and management is possible. This book explains pathological and clinical terminology, including a glossary of clinical request form abbreviations. A standardised step-wise approach to specimen handling is illustrated with simple line diagrams and highlights essentials of the histopathology report, relating them to appropriate specimen dissection. The integrated multidisciplinary team approach taken to the modern clinical management of patients is reflected by correlating patient presentation, diagnostic and staging investigations with histopathology specimens. Current WHO and TNM tumor classifications are referenced. This book will be of educative value and act as a reference tool for the medical undergraduate student, medical trainee in histopathology and the biomedical scientist, and as a useful aide memoire for the histopathology consultant.
  • 2008 Springer
    Habu, Sonoko; Nomura, Tatsuji; Watanabe, Takeshi.
    Basic Concept of Development and Practical Application of Animal Models for Human Diseases / Tatsuji Nomura, N. Tamaoki, A. Takakura and H. Suemizu, p. 25-51-- Humanized SCID Mouse Models for Biomedical Research / T. Pearson, D. L. Greiner and L. D. Shultz, p. 53-76 -- NOD/Shi-scid IL2rγnull (NOG) Mice More Appropriate for Humanized Mouse Models / M. Ito, K. Kobayashi and T. Nakahata, p. 77-86 -- Humanizing Bone Marrow in Immune-Deficient Mice / K. Ando, Y. Muguruma and T. Yahata, p. 87-94 -- The Differentiative and Regenerative Properties of Human Hematopoietic Stem/Progenitor cells in NOD-SCID/IL2rγnull Mice / F. Ishikawa, Y. Saito, S. Yoshida, M. Harada and L. D. Shultz, p. 95-107 -- Antigen-Specific Antibody Production of Human B Cells in NOG Mice Reconstituted with the Human Immune System / M. Ito, M. Shiina, Y. Saito, Y. Tokuda and Y. Kametani, et al., p. 109-124 -- Humanized Immune System (HIS) Mice as a Tool to Study Human NK Cell Development / N. D. Huntington and J. P. Di Santo, p. 125-131 -- Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice / S. Baenziger, P. Ziegler, L. Mazzucchelli, L. Bronz and R. F. Speck, et al., p. 133-148 -- Humanized Mice for Human Retrovirus Infection / Y. Koyanagi, Y. Tanaka, M. Ito and N. Yamamoto, p. 149-165 -- Functional and Phenotypic Characterization of the Humanized BLT Mouse Model / A. K. Wege, M. W. Melkus, P. W. Denton, J. D. Estes and J. V. Garcia, p. 167-177 -- Novel Metastasis Models of Human Cancer in NOG Mice / M. Nakamura and H. Suemizu, p. 179-196 -- In Vivo Imaging in Humanized Mice / H. Masuda, H. J. Okano, T. Maruyama, Y. Yoshimura and H. Okano, et al.
    Also available: Print – 2008
  • 2003 ScienceDirect
    Ortner, Donald J.
  • 2007 Springer
    Frischknecht, Friedrich; Shorte, Spencer L.
    Considerations for routine imaging -- Entering the portal: understanding the digital image recorded through a microscope -- Quantitative biological image analysis -- The open microscopy environment: a collaborative data modeling and software development project for biological image informatics -- Design and function of a light-microscopy facility -- Advanced methods and concepts -- Quantitative colocalisation imaging: concepts, measurements, and pitfalls -- Quantitative FRET microscopy of live cells -- Flourescence photobleaching and flourescence correlation spectroscopy: two complementary technologies to study molecular dynamics in living cells -- Single fluorescent molecule tracking in live cells -- From live-cell microscopy to molecular mechanisms: deciphering the functions of kinetochore proteins -- Cutting edge applications & utilities -- Towards imaging the dynamics of protein signalling -- New technologies for imaging and analysis of individual microbial cells -- Imaging parasites in vivo -- Computer-assisted systems for dynamic 3D reconstruction and motion analysis of living cells -- High-throughput/high-content automated image acquisition and analysis -- Cognition network technology: a novel multimodal image analysis technique for automatic identification and quantification of biological image contents -- High-content phenotypic cell-based assays.
  • 2007 Springer Protocols
    Fairchild, Paul J.
  • 2010 CRCnetBASE
    Christian, Donnell R.; Drilling, Stephanie.
  • 2002 Springer Protocols
    Didenko, Vladimir V.
  • 2015 Springer Protocols
    Hauptmann, Giselbert.
    Optimization of in situ hybridization and co-expression analysis in the central nervous system / Louisa Mezache ... [et al.] -- In situ hybridization methods for RNA visualization in C. elegans / Gina Broitman-Maduro and Morris F. Maduro -- Multicolored visualization of transcript distributions in Drosophila embryos / Iris Söll and Giselbert Hauptmann -- Exploring brain genoarchitecture by single and double chromogenic in situ hybridization (ISH) and immunohistochemistry (IHC) in whole-mount embryos / José Luis ... [et al.] -- Exploring brain genoarchitecture by single and double chromogenic in situ hybridization (ISH) and immunohistochemistry (IHC) on cryostat, paraffin, or floating sections / José Luis Ferran ... [et al.] -- Combined radioactive and nonradioactive double in situ hybridization (DISH) / Jong-Hyun Son and Ursula H. Winzer-Serhan -- One FISH, dFISH, three FISH : sensitive methods of whole- mount fluorescent in situ hybridization in freshwater planarians / David D. R. Brown and Bret J. Pearson -- Whole-mount in situ hybridization and immunohistochemistry in xenopus embryos / Edgar M. Pera ... [et al.] -- Manual and automated whole-mount in situ hybridization for systematic gene expression analysis in embryonic Zebrafish forebrain / Iris Söll and Giselbert Hauptmann -- Large-scale ISH on mouse brain sections for systematic gene expression analysis in developing mouse diencephalon / Tomomi Shimogori and Seth Blackshaw -- High-throughput in situ hybridization : systematical production of gene expression data and beyond / Lars Geffers and Gregor Eichele -- Analysis of embryonic gene expression patterns in the hagfish / Yasuhiro Oisi ... [et al.] -- Gene expression analysis of lamprey embryos / Fumiaki Sugahara, Yasunori Murakami, and Shigeru Kuratani -- Detection of mRNA and microRNA expression in basal chordates, amphioxus and ascidians / Simona Candiani, Greta Garbarino, and Mario Pestarino -- Analysis of gene expression in neurons and synapses by multi-color in situ hybridization / Leonid L. Moroz and Andrea B. Kohn -- Fluorescent in situ hybridization in primary hippocampal neurons to detect localized mRNAs / Jacki E. Heraud-Farlow, Tejaswini Sharangdhar, and Michael A. Kiebler -- Combining whole-mount in situ hybridization with neuronal tracing and immunohistochemistry / Jeremy S. Duncan ... [et al.] -- Fluorescent in situ hybridization detection of microRNAs in Newt tissue cryosections / Jamie Ian Morrison -- Subcellular transcript localization in Drosophila embryos and tissues visualized by multiplex-FISH / Julie Bergalet ... [et al.] -- Application of alkaline phosphatase-mediated azo dye staining for dual fluorescent in situ hybridization in Zebrafish / Giselbert Hauptmann, Gilbert Lauter, and Iris Söll -- Multiplex fluorescent RNA in situ hybridization via RNAscope / Hongwei Wang ... [et al.] -- Quantum dot-based in situ hybridization and immunohistochemistry to detect mRNA and protein at subcellular levels, comparison with studies using electron microscopy / Akira Matsuno ... [et al.] -- Quantitative multiplexed quantum dot based in situ hybridization in formalin-fixed paraffin-embedded tissue / Eleni Tholouli, Judith A. Hoyland, and Richard J. Byers -- Single and multiplexed fluorescent in situ hybridization using quantum dots nanocrystals in xenopus / Andriani Ioannou ... [et al.] -- Quantitative single-molecule mRNA fluorescent in situ hybridization in C. elegans / Remco A. Mentink ... [et al.] -- In situ detection of individual mRNA molecules with padlock probes and target-primed rolling-circle amplification in fixed mouse brain tissues / Thomas Hauling ... [et al.] -- Extended multiplexed fluorescent in situ hybridization by combinatorial encoding of individual transcripts / Lars Martin Jakt and Satoko Moriwaki -- Characterizing cellular identity at one cell resolution / Amaresh K. Ranjan, Mugdha V. Joglekar, and Anandwardhan A. Hardikar -- Transglutaminase-mediated in situ hybridization (TransISH) for mRNA detection in mammalian tissues / Katsuyuki Miyawaki, Sumihare Noji, and Noriho Kamiya -- ECHO-FISH for gene transcript detection in neuronal and other cells and subcellular compartments / Dan Ohtan Wang and Akimitsu Okamoto.
  • 2014 Springer Protocols
    Bal-Price, Anna; Jennings, Paul.
    In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism, and in vitro in vivo extrapolation. The book also addresses biological processes such as stress response pathways and mechanistic biomarkers and how these can be uncovered and measured using high content approaches. Reliable and authoritative, In Vitro Toxicology Systems will be of benefit not only to students, scientists, and regulators working in the field of chemical safety assessment but also to a wider scientific audience.
  • v. 1-2, 2006. Springer
    Marshall, Lisa A.; Morgan, Douglas W.; Stevenson, Christopher S.
    Also available: Print – v. 1-2., 2006
  • 2012 CRCnetBASE
    Aggarwal, Bharat B.; Guha, Sushovan; Krishnan, Sunil.
    "Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to chronic diseases through inflammation. While short-term, acute inflammation generated by the immune system serves a therapeutic role, chronic low-level inflammation that may persist "silently" for decades is responsible for chronic diseases. Inflammation, Lifestyle, and Chronic Diseases: The Silent Link describes the role of dysregulated inflammation in persistent and recurring diseases. It investigates links to lifestyle and presents research on how the suppression of proinflammatory pathways may provide opportunities for both prevention and treatment of chronic diseases. The book covers neurodegenerative diseases, pulmonary diseases, asthma, rheumatic and arthritic diseases, skin disease, heart disease, chronic wounds, infectious disease, neuropsychiatric disorders such as depression, gastrointestinal diseases, insulin resistance, and cancer, many of which are also diseases of old age. For each chronic disease, contributors review the clinical and scientific literature and examine current and potential therapies, including conventional pharmacotherapies as well as natural products. Noting that the long-term use of steroids and nonsteroidal anti-inflammatory drugs (NSAIDs) can cause adverse side effects, many of the chapters address the role of dietary agents such as fruits, vegetables, legumes, pulses, nuts, and spices as ideal anti-inflammatory agents that can be consumed regularly. The book also suggests directions for further research. Clinical and science researchers, students, and health professionals interested in the link between inflammation, lifestyle, and chronic diseases will find this an informative resource"--Provided by publisher.
  • 2003 Springer Protocols
    Willoughby, D. A.; Winyard, Paul G.
    Ikappab kinase and nf-kappab signaling in response to pro-inflammatory cytokines / M. Delhase -- Screening for inhibitors of transcription factors using luciferase reporter gene expression in transfected cells / D. Phippard and A.M. Manning -- Adhesion molecule expression on cytokine-stimulated human endothelial cells / S.L. Cuvelier and K.D. Patel -- Phagocytosis by inflammatory phagocytes: Experimental strategies for stimulation and quantification / M.R. Morris [and others] -- Cytosolic ca2+ measurement and imaging in inflammatory cells / S. Dewitt [and others] -- Detection and visualization of oxidase activity in phagocytes / M.B. Hallett, C. Cole and S. Dewitt -- Measurement of complement activation / T.E. Mollnes -- Measurement of matrix metalloproteinase activities in the medium of cultured synoviocytes using zymography / L. Troeberg and H. Nagase -- Measurement of aggrecanase-generated interglobular domain catabolites in the medium and extracts of cartilage explants using western blot analysis / C.E. Hughes, C.B. Little and B. Caterson -- In vitro model of human articular cartilage degradation / W.D. Shingleton -- Carrageenan-induced paw edema in the rat and mouse / C.J. Morris -- Pleural models of inflammation: Immune and nonimmune / A.R. Moore -- Models of acute inflammation in the ear / M. Gabor -- Migration of specific leukocyte subsets in response to cytokine or chemokine application in vivo / M. Perretti and S.J. Getting -- Inflammatory joint disease: Clinical, histological, and molecular parameters of acute and chronic inflammation and tissue destruction / N.L. McCartney-Francis, J. Chan and S.M. Wahl -- The assessment of inflammation, cartilage matrix, and bone loss in experimental monoarticular arthritis of the rat / M.P. Seed -- Collagen-induced arthritis / A.R. Moore -- Air-pouch models of inflammation and modifications for the study of granuloma-mediated cartilage degradation / P. Colville-Nash and T. Lawrence -- Quantitative analysis of angiogenesis using the murine chronic granulomatous air pouch / C.A. Alam -- Models of coronary artery occlusion and reperfusion for the discovery of novel antiischemic and antiinflammatory drugs for the heart / N.S. Wayman [and others] -- Assessment of anticolitic drugs in the trinitrobenzene sulfonic acid (tnbs) rat model of inflammatory bowel disease / B.J. Whittle, M. Cavicchi and D. Lamarque -- An in vivo model of ischemia/reperfusion and inflammation of the kidneys of the rat / P.K. Chatterjee and C. Thiemermann -- In vivo models of inflammation: Immune rejection and skin transplantation in vivo / I. Binet and K.J. Wood -- Wound healing: A model of dermal wound repair / A. Tomlinson and M.W. Ferguson -- An iconoclastic approach to pharmacodynamics in model systems: Their relevance to humans / D.R. Blake and G.J. Taylor -- Quantifying inflammation in vivo using radiolabeled antibodies and leukocytes / D. Marshall and D.O. Haskard -- Immunoperoxidase histochemistry for the detection of cellular adhesion molecule, cytokine, and chemokine expression in the arthritic synovium / Z. Szekanecz and A.E. Koch -- Roles of nitric oxide and superoxide in inflammation / D. Salvemini, H. Ischiropoulos and S. Cuzzocrea -- Analysis of nitrite and nitrate in the study of inflammation / C.A. Davies [and others] -- In vivo assays for cox-2 / C.C. Chan -- Measurement of 8-epi-pgf2alpha as a marker of lipid peroxidation in vivo by immunoaffinity extraction and gas chromatography-mass spectrometry / N.K. Gopaul and E.E. Anggard -- Laboratory assessment of the acute phase response: Using crp as a model / R.F. Ritchie and T.B. Ledue -- Assays of matrix metalloproteinases (mmps) and mmp inhibitors: Bioassays and immunoassays applicable to cell culture medium, serum, and synovial fluid / J.B. Catterall and T.E. Cawston.
  • 2005 Springer
    Cowan, Daniel F.
  • 2007 Ovid
    Wallach, Jacques B.
    Introduction to normal values (reference ranges) -- Critical values -- Core blood analytes: alterations by diseases -- Urine -- Cardiovascular diseases -- Respiratory diseases -- Gastrointestinal diseases -- Hepatobiliary diseases and diseases of the pancreas -- Central and peripheral nervous system disorders -- Musculoskeletal and joint diseases -- Hematology -- Metabolic and hereditary disorders -- Endocrine diseases -- Genitourinary diseases -- Infectious diseases -- Autoimmune and miscellaneous diseases -- Disorders due to physical and chemical agents -- Therapeutic drug monitoring and drug effects -- Body substances.
    Also available: Print – 2007
  • 2015 ClinicalKey
    Abdul-Karim, Fadi; Balzer, Bonnie Lei; Marchevsky, Alberto M.
    "When a patient is under anesthesia, every second counts. An intraoperative consultation provides essential information to ensure every operation has a successful conclusion. The stakes are high and the challenges are great -- no special stains, limited access for consultation with colleagues, often suboptimal slide preparation, and cases that may be out of a pathologist's normal sphere of practice. Diagnostic Pathology: Intraoperative Consultation is designed to be the best resource when pathologists need assistance. No time is wasted looking for information because each chapter is directed to a specific question posed by a surgeon, such as 'Does this patient have pancreatic cancer?', 'Is there an intrauterine pregnancy?', 'Does this patient have lung cancer?', or 'Are the margins free of carcinoma?' The clinical setting and what the surgeon needs to know -- and why -- are explained. Specimen processing (gross and microscopic), tissue selection, and reporting of results are detailed. All major entities in the differential diagnosis are described and shown in photographs. Major pitfalls are discussed and illustrated. This is the book every pathologist will want at their side the next time a page calls them to the frozen section room"--Provided by publisher.
  • 2012 Springer
    Welsh, Cynthia T.
    This volume acquaints the non-neuropathologist with the advantages of clinical-radiologic-pathologic correlation in neuropathology specimens, particularly in the intra-operative environment. This volume covers the enormous and sometimes insurmountable artifacts involed with freezing tissue, especially central nervous system tissue and how a good cytology preparation can add to, or even supply in isolation, a diagnosis. The text presents how to perform, and stain the cytologic preparations, and how to interpret them. The advantages and disadvantages of both frozen sections and cytologic preparations of various kinds are discussed. The presentation and format is very visual with diagrams, tables (including pearls and pitfalls), and many figures (therefore easy reading).An introductory chapter presents the pros and cons of supplemental cytology, the advantages and disadvantages of frozen sections, and the artifacts in both. Also included is an argument for knowing what the scans reveal and the impact of relevant patient history. The volume uses a case-based approach to show correlation between scan, history, frozen section and cytologic preparations.With the combination of extensive correlation of scans, cytology and frozen section with differential diagnosis, and analysis of the information crucial to the neurosurgeon in a case-based approach and with a special chapter written by a neuroradiologist, this volume is unique in presentation and utility and will be of great value to the trainee in pathology (residents/fellows), and practicing pathologists who include neuropathology in their practice, but do not have formal fellowship training in neuropathology.
  • 2015 Springer
    Keeling, Jean; Khong, T. Yee; Malcomson, Roger D. G.
    The Perinatal Postmortem from a Clinician?s Viewpoint -- The Perinatal Necropsy: Methodology -- Genetic and Epigenetic Basis of Development and Disease -- The Placenta and Umbilical Cord -- Perinatal Imaging -- Epidemiology of Fetal and Neonatal Death -- Pathology of Early Pregnancy Loss -- Congenital Abnormalities: Prenatal Diagnosis and Screening -- The Impact of Infection During Pregnancy on the Mother and Baby -- Perinatal Haematology -- Genetic Metabolic Disease -- Fetal Hydrops -- Pathology of Twinning -- Macerated Stillbirth -- Intrapartum Problems -- Prematurity -- Iatrogenic Disease -- Congenital Tumors -- The Cardiovascular System -- The Respiratory System -- The Alimentary Tract and Exocrine Pancreas -- Liver and Gallbladder -- The Urinary System -- The Reproductive System -- The Endocrine System -- The Reticuloendothelial System -- Brain Malformations -- Degenerative and Metabolic Brain Diseases -- Acquired Diseases of the Nervous System -- Skeletal Muscle and Peripheral Nerves -- The Skeletal System -- The Skin -- The Special Senses.- Forensic Aspects of Perinatal Pathology.
  • 2014 Springer
    Faa, Gavino; Fanos, Vassilios.
    This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding, and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life, and the correlation with renal carcinogenesis. Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists, and researchers with an interest in kidney diseases.
  • 2007 CRCnetBASE
    Salerno, Reynolds M.; Gaudioso, Jennifer Marie.
  • 2010 Thieme eNeurosurgery
    Oschmann, Patrick; Reiber, Hansotto; Wildemann, Brigitte.
    "Up-to-date, comprehensive, and beautifully illustrated, Laboratory Diagnosis in Neurology presents all the measuring parameters and methods relevant to the analysis of cerebrospinal fluid, serum, and tissues affected by neurologic disease and syndromes. Following an introduction to basic concepts, the book guides clinicians through the methods of CSF analysis, neurochemical examinations, clinical applications of neuroimmunology, microbiology and virology, neurogenetic tests, and evaluation of biopsies. Readers will learn about the equipment and various procedures, and how to effectively differentiate similar methods. In the final section of the book, the authors provide a systematic introduction to the pathophysiology and laboratory findings for specific clinical disorders, indications for particular test methods, and criteria for diagnostic interpretation"--Provided by publisher.
  • 2015 Springer
    Bennett, Sterling T.; Lehman, Christopher M.; Rodgers, George M.
  • 2007 Springer
    Bennett, Sterling T.; Lehman, Christopher M.; Rodgers, George M.
  • 2005 ScienceDirect
    Wolfe-Coote, Sonia.
  • 2014 CRCnetBASE
    Bisen, Prakash S.
    Microscopy -- Microtome -- pH and Buffers -- Spectrophotometer -- Centrifugation -- Radiation Biology -- Chromatography -- Separation Technology -- Histochemical Techniques -- Cytogenetics -- Biomolecules -- Enzymology -- Membranes -- Photosynthesis and Respiration -- Microbiology -- Soil Biology -- Virology -- Immunochemical Methods -- Genetic Engineering -- Molecular Biology -- Biosensors -- Enzyme Immobilization -- Plant Tissue Culture -- Animal Cell Science and Technology -- Bioprocess Engineering -- Environmental Biology -- Bioinformatics
  • 2014 ScienceDirect
    Kallner, Anders.
    Laboratory Statistics: Handbook of Formulas and Terms presents common strategies for comparing and evaluating numerical laboratory data. In particular, the text deals with the type of data and problems that laboratory scientists and students in analytical chemistry, clinical chemistry, epidemiology, and clinical research face on a daily basis. This book takes the mystery out of statistics and provides simple, hands-on instructions in the format of everyday formulas. As far as possible, spreadsheet shortcuts and functions are included, along with many simple worked examples. This book is a must-have guide to applied statistics in the lab that will result in improved experimental design and analysis. Comprehensive coverage of simple statistical concepts familiarizes the reader with formatted statistical expressionSimple, worked examples make formulas easy to use in real lifeSpreadsheet functions demonstrate how to find immediate solutions to common problemsIn-depth indexing and frequent use of synonyms facilitate the quick location of appropriate procedures.
  • 2013 ClinicalKey
    Berger, Barbara J.; Chernecky, Cynthia C.
    "Look no further for quick, complete answers to questions such as which laboratory tests to order or what the results might mean. Laboratory Tests And Diagnostic Procedures, 5th Edition covers more tests than any other reference of its kind, with over 900 lab tests and diagnostic procedures in all. In Part I, you'll find a unique, alphabetical list of hundreds of diseases, conditions, and symptoms, including the tests and procedures most commonly used to confirm or rule out a suspected diagnosis. Part II presents key information on virtually every laboratory and diagnostic test available. All test entries are up-to-date, concise, complete, and consistently presented, making this resource the perfect choice for students or practitioners who need fast, accurate information on diagnostic tests."--Publisher's website.
  • 2014 Ovid
    Lewin, Klaus J.; Jain, Dhanpat; Riddell, Robert H.; Weinstein, Wilfred M.
  • 2015 Springer
    O'Neil, Maura; Damjanov, Ivan; Taylor, Ryan M.
  • 2013 Springer Protocols
    Bäckvall, Helena; Lehtiö, Janne.
    Part I. Low Molecular Weight Analysis Methods. Narrow-Range Peptide Isoelectric Focusing as Peptide Prefractionation Method Prior to Tandem Mass Spectrometry Analysis / Maria Pernemalm -- Analysis of Peptides by Denaturing Ultrafiltrationand LC-MALDI-TOF-MS / Yanming An and Radoslav Goldman -- Stable Isotope Labeling Methods in Protein Profiling / Johan Lengqvist and AnnSofi Sandberg -- Development of MRM-Based Assays for the Absolute Quantitation of Plasma Proteins / Michael A. Kuzyk, Carol E. Parker, Dominik Domanski, and Christoph H. Borchers -- Mass Spectrometric Profiling of Low-Molecular-Weight Proteins / Matthias Rainer, Constantin Sajdik, and Günther K. Bonn -- Developing an iMALDI Method / Brinda Shah, Jennifer D. Reid, Michael A. Kuzyk, Carol E. Parker, and Christoph H. Borchers -- Analysis of Neuropeptides by MALDI Imaging Mass Spectrometry / Anna Ljungdahl, Jörg Hanrieder, Jonas Bergquist, and Malin Andersson -- Highly Multiplexed Antibody Suspension Bead Arrays for Plasma Protein Profiling / Kimi Drobin, Peter Nilsson, and Jochen M. Schwenk -- Part II. Bioinformatics Of Proteomics Data. Protein Quantification by Peptide Quality Control (PQPQ) of Shotgun Proteomics Data / Jenny Forshed -- Part III Methods Applied In Clinical Research. Collection and Handling of Blood Specimens for Peptidomics / Harald Tammen and Rudiger Hess -- An Automated RP-SCX Solid-Phase Extraction Procedure for Urinary Peptidomics Biomarker Discovery Studies / Crina I.A. Balog, Rico Derks, Oleg A. Mayboroda, and André M. Deelder -- Application of Phage Display for Ligand Peptidomics to Identify Peptide Ligands Binding to AQP2-Expressing Membrane Fractions / Byung-Heon Lee and Tae-Hwan Kwon -- Protein Expression Profiling of Brain Tumor Tissue Using SELDI-MS / Carl Wibom -- Comprehensive Analysis of MHC Ligands in Clinical Material by Immunoaffinity-Mass Spectrometry / Kie Kasuga.
  • 2011 Springer
    Pambuccian, Stefan E.; Bardales, Ricardo H.
    Introduction -- Overview of ancillary methods in lymph node FNA diagnosis -- Lymphadenopathy: anatomic and clinical clues to fine needle aspiration diagnosis -- Cytology of normal/reactive lymph nodes -- Overall assessment of the aspirate: diagnostic clues -- Overview of the algorithmic pattern-based approach to lymph node FNA -- The polymorphous lymphoid cell pattern -- The monotonous small-cell pattern -- The monotonous intermediate-sized cell pattern -- The monotonous large cell pattern -- The pleomorphic cell pattern -- Infectious and noninfectious lympadenitis -- Unusual neoplastic and nonneoplastic conditions of lymph nodes -- Pitfalls and limitations of FNA of lymph nodes.
  • 2011 ScienceDirect
    2011 ClinicalKey
    Burt, Alastair D.; Ferrell, Linda D.; MacSween, Roderick N. M.; Portmann, Bernard.
    1. Anatomy, pathophysiology and basic mechanisms of disease / James M. Crawford and Alastair D. Burt -- 2. Cellular and molecular techniques / Pierre Bedossa and Valerie Paradis -- 3. Developmental abnormalities and liver disease in childhood / Bernard C. Portmann and Eve A. Roberts -- 4. Genetic and metabolic liver disease / Richard J. Thompson, Bernard C. Portmann and Eve A. Roberts -- 5. Disorders of iron overload / Alan C. Paterson and Antonello Pietrangelo -- 6. Fatty liver disease : alcoholic and non-alcoholic / Elizabeth M. Brunt, Brent A. Neuschwander-Tetri and Alastair D. Burt -- 7. Acute and chronic viral hepatitis / Neil D. Theise, Henry C. Bodenheimer Jr. and Linda D. Ferrell -- 8. Other viral and infectious diseases and HIV-related liver disease / Sebastian B. Lucas, Sherif R. Zaki and Bernard C. Portmann -- 9. Autoimmune hepatitis / M. Kay Washington and Michael P. Manns -- 10. Diseases of the bile ducts / Yasuni Nakanuma, Yoh Zen and Bernard C. Portmann -- 11. Diseases of the gallbladder / Jorge Albores-Saavedra and Arturo Angeles-Angeles --12. Vascular disorders / Ian R. Wanless and Weei-Yuarn Huang -- 13. Hepatic injury due to drugs, herbal compounds, chemicals and toxins / James H. Lewis and David E. Kleiner -- 14. Tumours and tumour-like lesions of the liver / Zachary D. Goodman, Luigi M. Terracciano and Aileen Wee -- 15. Transplantation pathology / Stefan G. Hübscher and Andrew D. Clouston -- 16. Systemic disease / Alberto Quaglia, Alastair D. Burt, Linda D. Ferrell, Bernard C. Portmann.
  • 2014 CRCnetBASE
    Howard, Gary C.; Kaser, Matthew R.
    "This second edition provides guidance on all aspects of how to make and use antibodies for research, and commercial and industrial applications. All chapters are revised, updated, or expanded. New material in the book includes western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present descriptions of basic methods for making and using antibodies and describe basic laboratory techniques in detail. Each chapter includes introductory material, allowing for a better understanding of each concept. Practical examples are also included"--Provided by publisher.
  • 2015 Ovid
    Dunning, Marshall Barnett; Fischbach, Frances Talaska.
    Diagnostic testing -- Blood studies : hematology and coagulation -- Urine studies -- Stool studies -- Cerebrospinal fluid studies -- Chemistry studies -- Microbiologic studies -- Immunodiagnostic studies -- Nuclear medicine studies -- X-ray studies -- Cytologic, histologic, and genetic studies -- Endoscopic studies -- Ultrasound studies -- Pulmonary function, arterial blood gases (abgs), and electrolyte studies -- Prenatal diagnosis and tests of fetal well-being -- Special diagnostic, special specimen collection, and postmortem studies.
  • 2004 Ovid
    Fischbach, Frances Talaska; Dunning, Marshall Barnett.
    Also available: Print – 2004
  • 2009 Ovid
    Fischbach, Frances Talaska; Dunning, Marshall Barnett.
    Diagnostic testing -- Blood studies : hematology and coagulation -- Urine studies -- Stool studies -- Cerebrospinal fluid studies -- Chemistry studies -- Microbiologic studies -- Immunodiagnostic studies -- Nuclear medicine studies -- X-ray studies -- Cytologic, histologic, and genetic studies -- Endoscopic studies -- Ultrasound studies -- Pulmonary function, arterial blood gases (ABGs), and electrolyte studies -- Prenatal diagnosis and tests of fetal well-being -- Special diagnostic, special specimen collection, and postmortem studies.
  • 2010 ClinicalKey
    Lester, Susan Carole.
    Dr. Lester's Manual of Surgical Pathology, 3rd Edition offers complete, practical guidance on the evaluation of the surgical pathology specimen, from its arrival in the department to preparation of the final report. Inside, you'll find step-by-step instructions on specimen processing, tissue handling, gross dissection technique, histological examination, application of special stains, development of a differential diagnosis, and more. This thoroughly revised New Edition integrates cutting-edge procedures well as the latest staging and classification information. Coverage of the latest standards and procedures for the laboratory and handling of surgical pathology specimens are valuable assets to pathologists, pathology assistants, and anyone working in a pathology laboratory. Plus, with Expert Consult functionality, you'll have easy access to the full text online as well as all of the books illustrations and links to Medline. Features more than 150 tables that examine the interpretation of histochemical stains, immunohistochemical studies, electron microscopy findings, cytogenetic changes, and much more. Presents a user-friendly design, concise paragraphs, numbered lists, and bulleted material throughout the text that makes information easy to find. Offers detailed instructions on the dissection, description, and sampling of specimens. Includes useful guidance on operating room consultations, safety, microscope use, and error prevention. Explains the application of pathology reports to patient management. Discusses how to avoid frequent errors and pitfalls in pathology specimen processing.
  • 2005 Springer
    2005 Springer Protocols
    Rapley, Ralph; Walker, John M.
    Basic techniques in molecular biology / Ralph Rapley -- Probe design, production, and applications / Marilena Aquino de Muro -- Restriction enzymes: tools in clinical research / Gareth J.S. Jenkins -- Southern blotting as a diagnostic method / Bronwen Harvey and Pirkko Soundy -- Western blotting as a diagnostic method / Pirkko Soundy and Bronwen Harvey -- Principles and medical applications of the polymerase chain reaction / Bimal D. M. Theophilus -- Single strand conformation polymorphism (SSCP) analysis / Igor Vorechovsky -- Denaturing gradient gel electrophoresis (DGGE) / Jeroen H. Roelfsema and Dorien J.M. Peters -- Quantitative analysis of DNA sequences by PCR and solid phase sequencing / Anu Suomalainen and Ann-Christine Syvänen -- Introduction to capillary electrophoresis of DNA: biomedical applications / Beatriz Sanchez-Vega -- Mapping techniques / Simon G. Gregory -- Dideoxyfingerprinting for mutation detection / Ioannis Bossis, Antonios Voutetakis, and Constantine A. Stratakis -- Conformation sensitive gel electrophoresis / Marian Hill -- Amplification refractory mutation system and molecular diagnostics / Richard Kitching and Arun Seth -- Ligase chain reaction / Carla Osiowy -- Chemical cleavage of mismatch: theory and clinical applications / Neil V. Whittock and Louise Izatt -- The protein truncation test / Johan T. den Dunnen -- Linkage, allele sharing, and association / Mara Giordano -- Single nucleotide polymorphisms: technology and applications / Cyril Mamotte, Frank Christiansen, and Lyle J. Palmer -- cDNA microarrays / Philip G. Febbo -- Nucleic acid sequence-based amplification / Katherine Loens, D. Ursi, H. Goosens, and M. Ieven -- The oligonucleotide ligation assay / Faye A. Eggerding -- Quantitative taqman real-time PCR: diagnostic and scientific applications / Jörg Dötsch, Ellen Schoof, and Wolfgang Rascher -- Use of denaturing high-performance liquid chromatography in molecular medicine / Elizabeth L. Rugg and Gareth J. Magee -- Quantitative PCR / David Sugden -- Liquid chromatography-mass spectrometry of nucleic acids / Herbert Oberacher and Walther Parson -- Comparative genomic hybridization in clinical and medical research / Peng-Hui Wang, Yann-Jang Chen, and Chi-Hung Lin -- Bioinformatics tools for gene and protein sequence analysis / Bernd H.A. Rehm and Frank Reinecke -- In situ hybridization / Amanda D. Watters -- Enzyme-linked immunosorbent assay / William J. Jordan -- Protein therapeutics: mouse, humanized, and human antibodies / Benny K.C. Lo -- Karyotyping / Avery A. Sandberg, John F. Stone, and Zhong Chen -- Microsatellite analysis / Rachel E. Ibbotson and Anton E. Parker -- Analysis of chromosomal translocations / Andreas Hochhaus -- Differential display: theory and applications / Irina Gromova, Pavel Gromov, and Julio E. Celis -- Techniques for gene expression profiling / Mark P. Richards -- Capillary electrophoresis in clinical analysis / Margaret A. Jenkins and Sujiva Ratnaike -- Flow cytometry in the biomedical arena / James L. Weaver and Maryalice Stetler-Stevenson -- Immunocytochemistry / Patricia A. Fetsch -- Ribotyping in clinical microbiology / Patricia Severino and Sylvain Brisse -- Diagnostic applications of protein microarrays / Samir Hanash -- The human genome project / Rahul Chodhari and Eddie Chung -- Prenatal diagnosis of inborn errors of metabolism / Guy T.N. Besley -- Gene therapy: methods and application / Stella B. Somiari.
  • 2003 Springer Protocols
    Floyd, Robert A.; Hensley, Kenneth.
  • 2009 Springer Protocols
    Bilitewski, Ursula.
    DNA microarrays: an introduction to the technology / Ursula Bilitewski -- Discussion of the applicability of microarrays: profiling of leukemias / Torsten Haferlach ... [et al.] -- Expression profiling using Affymetrix GeneChip microarrays / Herbert Auer, David L. Newsom, and Karl Kornacker -- Genotyping of mutation in the beta-globin gene using DNA microarrays / Martin Dufva and Lena Poulsen -- Antibody-based microarrays / Christer Wingren and Carl A.K. Borrebaeck -- Application of protein ArrayTubes to bacteria, toxin, and biological warfare agent detection / Ralf Ehricht ... [et al.] -- Detection of known allergen-specific IgE antibodies by immunological methods / Barbara I. Fall and Reinhard NieSner -- Peptide microarrays for serum antibody diagnostics / Heiko Andresen and Frank F. Bier -- Microchips for cell-based assays / Martin Dufva -- Bio-cell chip fabrication and applications / Honggu Chun, Dong Soon Lee, and Hee Chan Kim -- Microchip capillary electrophoresis / Elaine T.T. Tay ... [et al.] -- Detection of enteropathogenic Escherichia Coli by microship capillary electrophoresis / Wai S. Law, Sam F.Y. Li, and Larry J. Kricka.
  • 2012 Springer
    Hegde, Madhuri R.; Hu, Peter C.; Lennon, Patrick Alan.
    Part 1. Current Molecular Laboratory Methods -- Specimen Collection, Handling, and Processing / Lindsy Hengesbach and John A. Gerlach -- DNA/RNA Isolation and Quantitation / Jing Wang -- Test Validation / Cindy McCloskey and S. Terence Dunn -- In Vitro Amplification Methods in Molecular Diagnostics / C. Alexander Valencia and Bradford Coffee -- Whole Genome Sequencing in the Clinical Laboratory / Tina Hambuch, Brad Sickler, Arnold Liao, Suneer Jain and Philip D. Cotter -- Estimation of Exon Dosage Using Real-Time Quantitative Polymerase Chain Reaction / Applications to Factor VIII Gene in Hemophilia A and Endoglin/ACVRL1 Genes in Hereditary Hemorrhagic Telangiectasia / Juliana Purrazzella and Arupa Ganguly -- Reporting Clinical Molecular Genetic Laboratory Results / Victor Wei Zhang and Lora J. H. Bean -- Part 2. Clinical Molecular Infectious Disease Testing -- HIV-1 Genotyping and Virtual Phenotyping / Fangling Xu and Jianli Dong -- COBAS® AmpliPrep/COBAS® TaqMan® HIV-1 Test, Version 2.0 / Tavat A. Buraruk and Charles E. Stager -- Hepatitis C Virus (HCV) Genotype Assay (LiPA) / Charles E. Stager and Tavat A. Buraruk -- COBAS® AmpliPrep/COBAS® TaqMan® HCV Test / Charles E. Stager and Tavat A. Buraruk -- Epstein-Barr Virus and Cytomegalovirus Viral Load Monitoring by Quantitative Real-Time Polymerase Chain Reaction / Su S. Chen, Seema Hai, Margaret L. Gulley and Rajyalakshmi Luthra -- Quantification of BK Viral Load / Hai Wu and Jianli Dong -- Molecular Diagnosis and Epidemiology of Rabies / Rodney E. Rohde and Bonny C. Mayes -- Pyrosequencing for Bacterial Identification / Laura Millecker and Ruth Ann Luna -- Other Pathogens of Significant Public Health Concern / Chris L. McGowin, Rodney E. Rohde and Greg C. Whitlock -- Part 3. Clinical Molecular Oncology Testing -- Gene Rearrangements Testing / Siby Sebastian, Juan Du and Rizwan Naeem -- Mutation Analysis in Cancer / Keyur Pravinchandra Patel, John Galbincea and Rajyalakshmi Luthra -- Minimal Residual Disease / Wesley O. Greaves and Rajyalakshmi Luthra -- Pyrosequencing in Cancer / Shalini Verma, Bedia A. Barkoh and Rajyalakshmi Luthra -- Clinical Applications of Microarrays in Cancer / Marilyn M. Li, Ankita Patel and Xiaofeng Hu -- Basic Theories and Clinical Applications of Molecular Flow Cytometry / Hua-Kang Wu, Hongli Chen and Peter C. Hu -- Part 4. Clinical Molecular Pre/Postnatal Testing -- Molecular Prenatal Diagnostic Testing / Joanna Wiszniewska and Christine M. Eng -- PCR Based Diagnosis of Fragile X Syndrome / Daniel J. Dykas and Allen E. Bale -- Part 5. Human Identity Testing -- Microsatellite Testing Short Tandem Repeat Profile Generation / Robin DeVille Guidry and Laura Gahn -- Parentage / Laura Gahn and Robin DeVille Guidry -- Part 6. Clinical Molecular Training -- Diagnostic Molecular Training / Peter C. Hu, Patrick Alan Lennon and Madhuri R. Hegde -- Molecular Diagnostics Point of Care Testing Training / Chang W. Lee and Peter C. Hu.
  • v.1-2, 2009 ClinicalKey
    Weidner, Noel.
    Part I: The Surgical Pathology Laboratory -- 1. Gross Room and Specimen Handling -- Lucien E. Nochomovitz -- 2. Intraoperative Consultations in Surgical Pathology -- Mahendra Ranchod -- 3. The Surgical Pathology Report -- Debra Hawes, Richard J. Cote, Noel Weidner -- 4. Anatomic Pathology Laboratory Information Systems -- Anil V. Parwani, Eric Schubert, William Gross, John Gilbertson, Michael J. Becich -- 5. Immunohistochemistry -- Debra Hawes, Shan-Rong Shi, David J. Dabbs, Clive R. Taylor, Richard J. Cote -- 6. Role of Electron Microscopy in Modern Diagnostic Surgical Pathology -- Robert A. Erlandson -- 7. Molecular Biology -- Sharon P. Wilczynski -- 8. The Essential Quality Improvement and Educational Programs in Surgical Pathology -- Robert R. Rickert -- 9. Medicolegal Issues in Surgical Pathology -- David B. Troxel -- Part 2: Head and Neck -- 10. Nasal Cavity, Paranasal Sinuses, and Nasopharynx -- Bruce M. Wenig, Mary Richardson -- 11. Larynx -- Lester D.R. Thompson -- 12. Salivary Glands -- Gary L. Ellis, Paul L. Auclair -- 13. Ear and Temporal Bone -- Bruce M. Wenig -- 14. Oral Cavity and Jaws -- Noel Weidner, Kurt Matthews, Joseph A. Regezi -- Part 3: Thoracic System -- 15. Lung -- Saul Suster, Cesar A. Moran -- 16. Serosal Membranes -- Lawrence M. Weiss -- 17. Mediastinum -- Saul Suster, Cesar A. Moran -- 18. Heart and Blood Vessels -- Allen Burke, Renu Virmani -- Part 4: Breast -- 19. Breast -- Noel Weidner -- Part 5: Gastrointestinal Tract -- 20. Esophagus -- Christopher A. Moskaluk -- 21. Stomach -- David Lewin, Klaus J. Lewin (deceased) -- 22. Small Intestine -- David Lewin, Klaus J. Lewin (deceased) -- 23. Large Intestine (Colon) -- Robert E. Petras, Wendy Frankel -- 24. Appendix -- Norman J. Carr, Leslie H. Sobin -- 25. Anus -- David A. Owen -- 26. Pancreas -- Ralph H. Hruban, Noriyoshi Fukushima, Robb E. Wilentz -- 27. Liver -- M. Kay Washington -- 28. Gallbladder and Extrahepatic Bile Ducts -- M. Kay Washington -- Part 6: Urinary Tract and Male Genital System -- 29. Non-Neoplastic Kidney -- Sharda G. Sabnis, Michael N. Koss, W.B. Ross, Zdena Pavlova -- 30. Renal Neoplasia -- John N. Eble, Liang Cheng -- 31. Bladder and Urethra -- Richard J. Cote, Anirban P. Mitra, Mahul B. Amin -- 32. Prostate -- David G. Bostwick, Isabelle Meiers -- 33. Penis and Scrotum -- Pheroze Tamboli, Antonio L. Cubilla, Mahul B. Amin -- 34. Testis and Paratestis Including Spermatic Cord -- Satish K. Tickoo, Pheroze Tamboli, Nancy E. Warner, Mahul B. Amin -- Part 7: Female Reproductive System -- 35. Vulva and Vagina -- Juan C. Felix, R. Tucker Burks, Charles A. Amezcua -- 36. Cervix -- Juan C. Felix, Thomas C. Wright, Jr., Charles A. Amezcua -- 37. Uterus -- Noel Weidner, Michael Peterson -- 38. Fallopian Tubes and Broad Ligament -- Noel Weidner, Michael Peterson -- 39. Ovaries -- Noel Weidner, Michael Peterson -- 40. Gestational Pathology -- Cynthia G. Kaplan -- Part 8: Hematolymphoid System -- 41. Lymph Nodes -- Karen L. Chang, Daniel A. Arber, Lawrence M. Weiss -- 42. Spleen -- Daniel A. Arber -- 43. Bone Marrow -- Daniel A. Arber -- Part 9: Endocrine System -- 44. Thyroid and Parathyroid -- Loretta L.Y. Tse, John K.C. Chan -- 45. Adrenal Gland -- Lawrence M. Weiss, Sean K. Lau -- Part 10: Soft Tissue and Skeletal System -- 46. Soft Tissues -- Lawrence M. Weiss -- 47. Joint and Bone Pathology -- Noel Weidner, Grace Y. Lin, Michael Kyriakos -- Part 11: Skin -- 48. Inflammatory Skin Conditions -- Još Antonio Plaza, Victor G. Prieto -- 49. Tumors of the Skin -- Saul Suster, Tai-Yuen Wong, Martin C. Mihm, Jr. -- Part 12: Nervous System -- 50. Pituitary -- David R. Hinton, Sylvia L. Asa -- 51. Central Nervous System Tumors -- Mahlon D. Johnson, James B. Atkinson -- 52. The Molecular and Genetic Basis of Neurodegenerative Diseases -- Thomas A. Tousseyn, Jeffrey P. Simko, David A. Gaskin, Stephen J. DeArmond -- 53. Muscle and Nerve Biopsy -- James B. Atkinson, Mahlon D. Johnson, Thomas W. Bouldin, William O. Whetsell, Jr. -- 54. Eye and Ocular Adnexa -- Somsiri Sukavatcharin, Narsing A. Rao.
  • 2011 Springer
    Das, Undurti N.
    The book describes how the balance between pro- and anti-inflammatory molecules is related to health and disease. It is suggested that many diseases are initiated and their progress is influenced by inflammatory molecules and a decrease in the production and/or action of anti-inflammatory molecules and this imbalance between pro- and anti-inflammatory molecules seems to have been initiated in the perinatal period. This implies that strategies to prevent and manage various adult diseases should start in the perinatal period. An alteration in the metaolism of essential fatty acids and their anti-inflammatory molecules such as lipoxins, resolvins, protecitns, maresins and nitrolipids seems to play a major role in the pathobiology of several adult diseases. Based on these concepts, novel therapeutic approaches in the management of insulin resistance, obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, lupus, rheumatoid arthritis and other auto-immune diseases are presented. Based on all these evidences, a unified concept that several adult diseases are due to an alteration in the balance between pro- and anti-inflammatory molecules is discussed and novel methods of their management are presented.
  • 2014 Springer
    Highsmith, W. Edward.
    Molecular Diagnostics: 12 Tests That Changed Everything focuses on specific laboratory tests and emphasizes how the availability of these tests has altered how clinicians treat their patients. Presented as a standard outline, each chapter focuses on a specific molecular test and provides background on the test and its clinical applications. Continuing with some discussion on how the test is done, interpreted, and used clinically, each chapter then concludes with a discussion of how that test has changed the way medicine is practiced with respect to the disease or condition in question. Authored by renowned experts in the field, Molecular Diagnostics: 12 Tests That Changed Everything is a valuable resource for pathologists, pathology residents, laboratory directors, development personnel, lab medicine fellows and those working in the broad area of oncology, infectious disease and genetics.
  • 2014 Springer
    Hosler, Gregory A.; Murphy, Kathleen M.
    "This textbook presents the current (and near-future) state of affairs of molecular testing as it pertains to the dermatology patient. It focuses on practical applications of molecular diagnostics over a cross-section of dermatologic disease, including melanoma, lymphoma, soft tissue tumors, genodermatoses, and infectious disease. It includes practical advice to those ordering molecular tests as well as to those considering performing such tests, providing a potential template for a comprehensive dermatologic molecular diagnostics test menu. Pitfalls of interpretation and algorithmic approaches to testing are included. The textbook is directed towards all readers -- clinicians, pathologists, laboratorians, and other inquisitive minds -- independent of their level of molecular expertise, to provoke thought or perhaps even change practice. The context for the book is the rapid evolution of the field of molecular diagnostics, which is becoming more pervasive in all disciplines of medicine, including dermatology. This is indeed an exciting time in dermatology. Molecular testing is now incorporated into all aspects of patient management, including diagnostics (identifying and classifying disease), prognostics (predicting disease course), and theranostics (predicting response to therapy). For example, molecular tests are now used to detect germline mutations that result in genodermatoses, somatic genetic events that characterize tumors such as melanoma and sarcomas, and genetic material of otherwise undetectable infectious organisms. For melanoma and lymphoma, testing can potentially predict tumor behavior and modify patient staging. Regarding theranostics, molecular tests that identify specific mutations in proto-oncogenes, such as BRAF and others, are now used to predict which patients will respond to designer targeted therapies. Molecular theranostics has revolutionized the entire treatment paradigm for patients with advanced melanoma, replacing "excise and pray" approaches with personalized medicine."--Publisher's website.
  • 2011 Springer
    Murphy, Michael J.
    Springer eBooks.
  • 2013 Springer
    Cheng, Liang; Eble, John N.; Zhang, David Y.
    Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
  • 2015 Springer
    Dumur, Catherine Isabelle; Garrett, Carleton T.; Idowu, Michael Ola.
    Part I. Overview of Basic Cellular Biology -- 1. Normal molecular biology and definition of terms -- 2. Pathologic changes: Chromosomes, genes, DNA, RNA and proteins -- 3. Standard nomenclature -- introduction and brief overview -- Part II. Molecular Oncology Methodology -- 4. General principles of Oncology testing -- 5. Molecular methodologies -- 6. General principles of validating a molecular test -- Part III. Molecular testing in Solid Tumors -- 7. Lung and mediastinum -- 8. Breast -- 9. Head and neck (salivary glands) -- 10. Thyroid and parathyroid (endocrine) -- 11. Gastrointestinal and Pancreatobiliary -- 12. Soft tissue -- 13. Genitourinary system -- 14. Central Nervous System -- 15. Skin and adnexa -- 16. Common Hereditary Cancer Syndromes -- Part IV. The future is here -- 17. Application of next generation sequencing -- Part V. Quality Assurance and Regulatory affairs -- 18. Quality Assurance -- pre-analytic, analytic and post-analytic -- 19. Regulatory affairs (including accreditation) -- 20. Coding and re-imbursement.

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In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.

A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.

A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.

Over 10,000 notes outline the status of specific infections within each country.

Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.

Provides online, full-text access to Springer's journal titles as well as journals from other publishers.

Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.

Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.
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