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Oncology

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  • Introduction /M. Alma Rodriguez --History of MD Anderson's tumor registry /Sarah H. Taylor --Statistical methods /Geoffrey G. Giacco, Sarah H. Taylor and Kenneth R. Hess --Breast cancer /Aman U. Buzdar ... [et al.] --Prostate cancer /Deborah A. Kuban ... [et al.] --Non-small cell lung cancer /Ritsuko Komaki, Anne S. Tsao, and Reza J. Mehran --Small cell lung cancer /Frank V. Fossella --Colon cancer /Cathy Eng, Patrick Lynch, and John Skibber --Ovarian cancer /Robert L. Coleman and David M. Gershenson --Cervical cancer /Patricia J. Eifel and Charles Levenback --Endometrial cancer /Thomas Burke ... [et al.] --Pancreatic cancer (exocrine) /Jason Fleming ... [et al.] --Kidney cancer /Scott E. Delacroix Jr. ... [et al.] --Bladder cancer /Robert S. Svatek ... [et al.] --Cutaneous melanoma /Jeffrey E. Gershenwald, Geoffrey G. Giacco, and Jeffrey E. Lee --Liver cancer /Evan S. Glazer and Steven A. Curley --Esophageal cancer /Linus Ho ... [et al.] --Gastric cancer /Alexandria T. Phan and Paul F. Mansfield --Acute myeloid leukemia /Emil J. Freireich --Chronic lymphocytic leukemia/small lymphocytic lymphoma /Apostolia-Maria Tsimberidou and Michael J. Keating --Hodgkin lymphoma /Michelle Fanale ... [et al.] --Non-hodgkin indolent B-cell lymphoma /Sattva S. Neelapu --Non-hodgkin aggressive B-cell lymphoma /M. Alma Rodriguez --Multiple myeloma /Donna Weber and Raymond Alexanian --Head and neck cancer /Ehab Hanna ... [et al.] --Thyroid cancer /Steven I. Sherman, Nancy Perrier, and Gary L. Clayman --Soft tissue sarcomas /Vinod Ravi, Raphael Pollock, and Shreyaskumar R. Patel --Sarcomas of bone /Valerae Lewis.
  • AACR Education book HighWire, Latest ed. only
  • Print Material
  • Approaching the treatment of AML from a biological perspective : an overview / Farhad Ravandi and Francis Giles -- Aberrant transcription factors in AML / Alan D. Friedman -- Myelodysplasia-related AML / Jane E. Parker -- Therapy-related AML / Lucy A. Godley and Michelle Le Beau -- The DNA damage response, DNA repair, and AML / David P. Steensma -- Altered apoptosis in AML : potential implications for pathogenesis and therapeutic response / Ruben A. Mesa and Scott H. Kaufmann -- Drug resistance transporters in AML / Douglas D. Ross -- Impact of cytogenetics on clinical outcome in AML / David Grimwade -- APL : a classic tale of bench to bedside / Olga Frankfurt ... [et al.] -- Emerging therapeutics for AML / Edward A. Sausville --FLT3 : a prototype receptor tyrosine kinase target in AML / Mark Levis -- Farnesyl transferase inhibitors in the therapy of AML / Jeffrey E. Lancet -- Modulating gene expression as a therapeutic approach in the treatment of AML / Tamer Fandy, Hetty Carraway, and Steven D. Gore -- Differentiation therapy in AML / Tara L. Lin and William Matsui -- Stem cell transplantation for AML / Javier Bolaños-Meade and Richard J. Jones -- Tumor vaccines in leukemia / Ivan Borrello -- Treatment, outcomes, and challenges of newly diagnosed AML in children and adolescents / Robert J. Arceci -- AML in older adults / Richard M. Stone -- Dameshek smiles : molecular clues to the chronic myeloproliferative disorders unmasked / Jason Gotlib -- New designs for clinical trials / Elihu Estey.
  • APL as a paradigm in biomedical research : a journey toward the cure / P.P. Pandolfi -- Mouse models of acute promyelocytic leukemia / S.C. Kogan -- The PLZF gene of t(11;17)-associated APL / M.J. McConnell and J.D. Licht -- SUMO, the three Rs and cancer / J.-S. Seeler ... [et al.] -- Emerging role for microRNAs in acute promyelocytic leukemia / C. Nervi ... [et al.] -- The theory of APL revisited / P.P. Scaglioni and P.P. Pandolfi -- Treatment of acute promyelocytic leukemia by retinoids / P. Fenaux, Z.Z. Wang, and L. Degos -- Arsenic trioxide and acute promyelocytic leukemia : clinical and biological / Z. Chen ... [et al.] -- Front line clinical trials and minimal residual disease monitoring in acute promyelocytic leukemia / F. Lo-Coco and E. Ammatuna -- Histone deacetylase inhibitors in APL and beyond / K. Petrie, N. Prodomou, and A. Zelent -- Monoclonal antibody therapy of APL / P.G. Maslak, J.G. Jurcic, and D.A. Scheinberg -- Targeting APL fusion proteins by peptide interference / A. Melnick -- The design of selective and non-selective combination therapy for acute promyelocytic leukemia / Y. Jing and S. Waxman.
  • Adrenocortical carcinoma 2011, Springer
  • A perspective on the treatment of acute lymphoblastic leukemia in adults -- Acute lymphocytic leukemia: clinical features and making the diagnosis -- The biology of adult acute lymphoblastic leukemia -- Minimal residual disease in acute lymphoblastic leukemia -- Cytogenetics -- Acute lymphoblastic leukemia: epidemiology -- Prognostic factors in adult acute lymphoblastic leukemia (ALL) -- The generalized care of the patient with acute lymphoblastic leukemia -- Treatment of acute lymphoblastic leukemia in middle-age and older adults -- Pharmacology of acute lymphoblastic leukemia therapy -- Assessment of response to treatment -- T-cell acute lymphoblastic leukemia -- Burkitt lymphoma and leukemia -- Treatment of acute lymphoblastic leukemia in young adults -- Philadelphia chromosome positive acute lymphoblastic leukemia -- Molecular therapies -- Treatment of relapsed acute lymphoblastic leukemia -- Allogeneic stem cell transplantation for acute lymphoblastic leukemia in adults -- Hematopoietic stem cell transplantation in Philadelphia-positive acute lymphoblastic leukemia -- Special challenges: genetic polymorphisms and therapy -- Late consequences of therapy of acute lymphoblastic leukemia -- Immunotherapy for acute lymphoblastic leukemia -- Unique subtypes in acute lymphoblastic leukemia.
  • Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. CLL has a highly varied clinical course. While advances in CLL therapy are noted, many patients still succumb to this illness. Like most progress in medicine, solid advances in the diagnosis, prognosis and treatment of CLL are rooted in an in-depth understanding of the basic and translational biology of CLL. In this book, CLL experts have contributed state-of-the-art summaries of various important aspects of CLL biology and have discussed the translational implication of such findings. This book, which is directed at physicians and researchers alike, aims to educate broadly and deeply. Intentionally, the many aspects and nuances of CLL clinical care that can only really be appreciated through direct patient care are not covered here, but instead, the book presents basic aspects of CLL that underlie many of the contemporary decisions that are made in CLL research and clinical settings. We hope that this book will critically inform the community and stimulate interest in CLL, which will ultimately translate into better CLL research, prognostication and therapy, with the end goal of providing a better outlook for patients afflicted with this common leukemia.
  • Repair of DNA Interstrand Cross-links Produced by Cancer Chemotherapeutic Drugs /Anderson T. Wang, Peter J. McHugh --DNA-PK, a Pharmacological Target in Cancer Chemotherapy and Radiotherapy? /Bernard Salles D.V.M., Ph.D. --Growth Factor Receptor Signaling, DNA Damage Response, and Cancer Cell Susceptibility to Chemotherapy and Relapses /Moulay Alaoui-Jamali, Amine Saad, Gerald Batist --The Relationship Between DNA-Repair Genes, Cellular Radiosensitivity, and the Response of Tumors and Normal Tissues to Radiotherapy /David Murray, Matthew Parliament --Important Roles of ERCC1 in DNA Repair and Targeted Therapy /Jennifer J. Hu, Joseph de la Garza --The Role of BRCA1 and BRCA2 in Anticancer Drug Therapy /Andrew Y. Shuen, Jorge S. Reis-Filho --DNA-PK in CLL Chemotherapy /L. Amrein, D. Davidson, R. Aloyz, L. Panasci --Poly(ADP) Ribose Polymerase at the Interface of DNA Damage Signaling and DNA Repair /Jana Krietsch, Michele Rouleau, Michel Lebel --Cellular Protection Against the Antitumor Drug Bleomycin /Dindial Ramotar Ph.D., Mustapha Aouida Ph.D. --ATR as a Therapeutic Target /Fiona K. Middleton, Nicola J. Curtin --Telomeres, Telomerase, and DNA Damage Response in Cancer Therapy /Raina A. Tamakawa, Helen B. Fleisig --RAD51 Is a Key Protein of DNA Repair and Homologous Recombination in Humans /Alexander V. Mazin Ph.D., Olga M. Mazina.
  • Genome instability, checkpoints, and the cell cycle. Comparison of DNA replication in Xenopus laevis and simian virus 40 / Maren Oehlmann, Cathal Mahon, and Heinz-Peter Nasheuer. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors / P. Mathijs Voorhoeve ... [et al.] An investigation into 53BP1 complex formation / Kevin C. Roche and Noel F. Lowndes. Short abstracts--session I -- Tumor and microenvironment interactions. Tumor promotion by tumor-associated macrophages / Chiara Porta ... [et al.] The AP-2[alpha] transcription factor regulates tumor cell migration and apoptosis / Francesca Orso ... [et al.] Modulatory actions of neuropeptide Y on prostate cancer growth: role of MAP kinase/ERK 1/2 activation / Massimiliano Ruscica ... [et al.] Short abstracts--session II -- Animal models. The Arf tumor suppressor in acute leukemias: insights from mouse models of Bcr-Abl-induced acute lymphoblastic leukemia / Richard T. Williams and Charles J. Sherr. Short abstracts--session III -- Transcription and epigenetics. Short abstracts--session IV -- High-throughput approaches and imaging. Identification and validation of the anaplastic large cell lymphoma signature / Roberto Piva, Elisa Pellegrino, and Giorgio Inghirami. Cell-cycle inhibitor profiling by high-content analysis / Fabio Gasparri, Antonella Ciavolella, and Arturo Galvani. Short abstracts-session V -- Novel pathways and therapeutic targets. Regulation for nuclear targeting of the Abl tyrosine kinase in response to DNA damage / Kiyotsugu Yoshida. Short abstracts--session VI -- Poster abstracts.
  • This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed nutrition and cancer from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the -omics) that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions. Advances in Nutrition and Cancer will be an invaluable source of topical information for all researchers and clinicians with an interest in this field.
  • Management of Peritoneal Surface Malignancy: A Short History / Paul H. Sugarbaker -- The Natural History of Free Cancer Cells in the Peritoneal Cavity / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Yoshio Endou, et al. -- Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer / Linmarie Ludeman and Neil A. Shepherd -- Principles of Perioperative Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis / Eelco de Bree and Dimitris D. Tsiftsis -- Experimental and Pharmacokinetic Studies in Intraperitoneal Chemotherapy: From Laboratory Bench to Bedside / Eelco de Bree and Dimitris D. Tsiftsis -- Technology for the Delivery of Hyperthermic Intraoperative Intraperitoneal Chemotherapy: A Survey of Techniques / Amod A. Sarnaik, Jeffrey J. Sussman, Syed A. Ahmad, Benjamin C. McIntyre and Andrew M. Lowy -- Adjuvant Intraperitoneal Chemotherapy: A Review / Paul H. Sugarbaker -- Clinical Research Methodology in Peritoneal Surface Oncology: A Difficult Challenge / François-Noël Gilly, Olivier Glehen, Annie C. Beaujard and Eddy Cotte -- Lessons Learnt from Clinical Trials in Peritoneal Surface Oncology: Colorectal Carcinomatosis / Frans A. N. Zoetmulder and Vic J. Verwaa -- Experimental Models and Questions in Basic Science Research for Pseudomyxoma Peritonei / Laura A. Lambert, Donald H. Lambert and Paul Mansfield -- Peritoneal Carcinomatosis of Colorectal Origin: Recent Advances and Future Evolution Toward a Curative Treatment / Dominique Elias and Diane Goere -- Pathologic Characterization and Differential Diagnosis of Malignant Peritoneal Mesothelioma / Nelson G. Ordóñez -- Advances in Clinical Research and Management of Diffuse Peritoneal Mesothelioma / Marcello Deraco, Dario Baratti, Nadia Zaffaroni, Antonello Domenico Cabras and Shigeki Kusamura -- Advances in the Management of Gastric Cancer with Peritoneal Dissemination / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Masayuki Nemoto, et al. -- Intraperitoneal Chemotherapy in the Management of Ovarian Cancer / Maurie Markman.
  • [1.] Non-genomic Action of Steroid Hormones: More Questions than Answers / Antimo Migliaccio, Gabriella Castoria, Antonio Bilancio, Pia Giovannelli, Marzia Di Donato and Ferdinando Auricchio -- Part I. Breast Cancer -- [2.] Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling / Guillermo P. Vicent, Roser Zaurin, Cecilia Ballaré, A. Silvina Nacht, Roni H. G. Wright, Francois Le Dily, Giancarlo Castellano, Jofre Font-Mateu and Miguel Beato -- [3.] Cooperative Interactions Between c-Src, Estrogen Receptors and Receptor Tyrosine Kinases in Breast Cancer / Sarah J. Parsons, Jessica E. Pritchard, Emily M. Fox and Margaret A. Shupnik -- [4.] Cross Talk Between ER[alpha] and Src Signaling and Its Relevance to ER Status and Hormone Responsiveness / Jun Sun, Wen Zhou, Zafar Nawaz and Joyce M. Slingerland -- [5.] Post-translational Modifications of ER Alpha in Rapid Estrogen's Action / Muriel Le Romancer, Coralie Poulard, Stéphanie Sentis, and Laura Corbo -- [6.] Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancer / Marina Ines Flamini, Angel Matias Sanchez, Xiao-Dong Fu and Tommaso Simoncini -- [7.] Unraveling the Role of GPER in Breast Cancer / Rosamaria Lappano and Marcello Maggiolini -- [8.] Nongenomic Actions of Estrogens and Xenoestrogens Affecting Endocrine Cancer Cells / Cheryl S. Watson, Dragoslava Zivadinovic, Yow-Jiun Jeng, Rebecca A. Alyea, Terumi Midoro-Horiuti, Randall Goldblum and Anannya Banga -- Part II. Prostate Cancer -- [9.] Differential Functions of Stromal and Epithelial Androgen Receptor in Prostate Cancer Before and After Castration Resistant Stage / S. Lee, K.-P. Lai, S. Yeh and C. Chang -- [10.] Role of Androgens and Androgen Receptor in Prostate Cancer: Genomic and Non-Genomic Actions / Sara Marchiani, Lara Tamburrino, Monica Muratori, Lorella Bonaccorsi, Gianni Forti and Elisabetta Baldi -- [11.] Mechanisms of Signal Transduction in Prostate Cancer: The Role of PI3-Kinase Pathway in Androgen Action / Laurent Morel and Silvère Baron -- [12.] The IGF-I Axis in Prostate Cancer: The Role of Rapid Steroid Actions / Antonino Belfiore -- Androgen Receptor Pathway in Prostate Cancer: Old Target and New Drugs / Christophe Massard and Karim Fizazi -- Part III. New Tools for Steroid Receptor Analysis and Regulatory Networks -- [13.] Quantitative Visualization of Sex Steroid Receptor Functions: AR and ER[alpha] / Michael J. Bolt, Sean M. Hartig, Adam T. Szafran, Sanjay N. Mediwala, Marco Marcelli and Michael A. Mancini -- [14.] Micropatterned Surfaces as Tools for the Study of the Rapid Non-genomic Actions of Steroid Receptors / Andrew C. B. Cato, Emmanuel Oppong and Sylwia Sekula-Neuner.
  • Dawn of a new era in molecular cancer therapeutics -- Obstacles and opportunities in the clinical development of targeted therapeutics -- Tumor models for preclinical development of targeted agents -- Angiogenesis inhibitors: what is the clinical future? -- Epidermal growth factor receptor (EGFR) inhibitors in cancer therapy -- Cell survival signaling during apoptosis: implications in drug resistance and anti-cancer therapeutic development -- Targeted histone deacetylase inhibition for cancer prevention and therapy -- Inhibitors of cyclin-dependent kinase modulators for cancer therapy -- Targeting cyclooxygenase-2 for cancer prevention and treatment -- Antisense approaches in drug discovery and development -- Preclinical development of Alimta (Pemetrexed LY231514), a multitargeted antifolate.
  • Roles of the TNF family in tissue homeostasis and normal development -- Novel aspects of signaling activation by the TNF family: novel aspects of the functions of the TRAFs and cIAPs -- Novel aspects of signaling activation by the TNF: ubiquitin modification of signaling proteins -- Novel aspects of signaling activation by the TNF family: TNF signaling and gene regulatory networks -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: roles of the TNF family in infectious diseases -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: interrelationship of the TNF family and pattern recognition receptor signaling -- Novel aspects of immune regulation by the TNF family -- Control of lymphocyte function and repertoire by the TNF family -- Advances in applying our knowledge to therapy: mechanisms of pathological and therapeutic effects of the TNF family -- Advances in applying our knowledge to therapy: rational design of new means for therapeutic modulation of function of the TNF family -- Roles of the TNF family in neuronal development, function, and pathology -- Cell death mechanisms controlled by the TNF family -- Contributors to abstracts of talks and posters at the 12th TNF Conference -- Abstracts of talks and posters presented at the 12th TNF Conference.
  • Ch. 1. AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression -- Ch. 2. AEG-1/MTDH/LYRIC: clinical significance -- Ch. 3. AEG-1/MTDH/LYRIC: signaling pathways, downstream genes, interacting proteins, and regulation of tumor angiogenesis -- Ch. 4. Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer -- Ch. 5. Drug resistance mediated by AEG-1/MTDH/LYRIC -- Ch. 6. The role of AEG-1/MTDH/LYRIC in the pathogenesis of central nervous system disease -- Ch. 7. AEG-1/MTDH/LYRIC in liver cancer -- Index.
  • General information on cancer staging and end-results reporting -- Head and neck -- Digestive system -- Thorax -- Musculoskeletal sites -- Skin -- Breast -- Gynecologic sites -- Genitourinary sites -- Ophthalmic sites -- Central nervous system -- Lymphoid neoplasms -- Personnel and contributors.
  • Alcohol and cancer 2011, Springer
  • The presence of oriented features in images often conveys important information about the scene or the objects contained; the analysis of oriented patterns is an important task in the general framework of image understanding. As in many other applications of computer vision, the general framework for the understanding of oriented features in images can be divided into low- and high-level analysis. In the context of the study of oriented features, low-level analysis includes the detection of oriented features in images; a measure of the local magnitude and orientation of oriented features over the entire region of analysis in the image is called the orientation field. High-level analysis relates to the discovery of patterns in the orientation field, usually by associating the structure perceived in the orientation field with a geometrical model. This book presents an analysis of several important methods for the detection of oriented features in images, and a discussion of the phase portrait method for high-level analysis of orientation fields. In order to illustrate the concepts developed throughout the book, an application is presented of the phase portrait method to computer-aided detection of architectural distortion in mammograms.
  • Androgen action and modulation of prostate and prostate cancer growth : an historical perspective / Shutsung Liao ... [et al.] -- Clinical progression to castration-recurrent prostate cancer / Mark Pomerantz and Philip Kantoff -- Differential roles of androgen receptor in prostate development and cancer progression / Shuyuan Yeh ... [et al.] -- Imaging androgen receptor function in vivo / Michael Carey and Lily Wu -- Increased expression of genes converting adrenal androgens to testosterone in castration-recurrent prostate cancer / Steven P. Balk -- Androgen-metabolic genes in prostate cancer predisposition and progression / Juergen K.V. Reichardt and Ann W. Hsing -- Effect of steroid 5[alpha]-reductase inhibitors on markers of tumor regression and proliferation in prostate cancer / Lynn N. Thomas and Roger S. Rittmaster -- 5[alpha]-reductase isozymes in castration-recurrent prostate cancer / Mark A. Titus and James L. Mohler -- Improving intermittent androgen-deprivation therapy : OFF cycle and the role of steroid 5[alpha]-reductase inhibitors / Shubham Gupta, Daniel Shevrin, and Zhou Wang -- Insights from AR gene mutations / Grant Buchanan ... [et al.] -- Functional motifs of the androgen receptor / Elizabeth M. Wilson -- The role of the androgen receptor polyglutamine tract in prostate cancer : in mice and men / Diane M. Robbins -- The androgen receptor coactivator-binding interface / Eva Estébanez-Perpiñá and Robert J. Fletterick -- Co-regulators and the regulation of androgen receptor action in prostate cancer / Irina U. Agoulnik and Nancy L. Weigel -- Androgen receptor coregulators and their role in prostate cancer / Latif A. Wafa, Robert Snoek, and Paul S. Rennie -- Interaction of the androgen receptor ligand-binding domain with the n-terminal domain and with coactivators / Jan Trapman -- Multitasking and interplay between the androgen receptor domains / F.Claessens, T. Tanner, and A. Haelens -- Chromatin remodeling and androgen receptor-mediated transcription / Li Jia ... [et al.] -- Ligand-independent androgen receptor activity / Scott M. Dehm and Donald J. Tindall -- Role of IL-6 in regulating the androgen receptor / Zoran Culig and Alfred Hobisch -- The role of cyclic AMP in regulating the androgen receptor / Marianne D. Sadar --Cellular and molecular signatures of androgen ablation of prostate cancer / Clifford G. Tepper and Hsing-Jien Kung -- Tissue levels of androgens in castration-recurrent prostate cancer / James L. Mohler and Mark A. Titus -- Unique effects of wnt signaling on prostate cancer cells : modulation of the androgen signaling pathway by interactions of the androgen receptor gene and protein with key components of the canonical wnt signaling pathway / Matthew J. Tanner ... [et al.] -- The role of foxa proteins in the regulation of androgen receptor activity / David J. DeGraff ... [et al.] -- Androgen receptor as a licensing factor for DNA replication / Donald J. Vander Griend and John T. Isaacs -- Androgen-regulated genes in the prostate / Nigel Clegg and Peter S. Nelson -- Mapping the androgen receptor cistrome / Qianben Wang and Myles Brown -- Differential regulation of clusterin isoforms by the androgen receptor Tanya K. Day, Colleen C. Nelson, and Martin E. Gleave -- Androgen regulation of prostate cancer gene fusions / Rou Wang, Scott A. Tomlins, and Arul M. Chinnaiyan -- Androgens and the lipogenic switch in prostate cancer / Johannes V. Swinnen ... [et al.] -- Molecular biology of novel targets identified through study of castration-recurrent prostate cancer / Philip A. Watson and Charles L. Sawyers -- Selenium and androgen receptor in prostate cancer / Nagalakshmi Nadiminty and Allen C. Gao.
  • Angiogenesis inhibition 2010, Springer
    Angiopoietins / Yvonne Reiss -- HIF-1 alpha and cancer therapy / Mei Yee Koh, Tally R. Spivak-Kroizman, Garth Powis -- Chemokines / Andreas Hippe, Bernhard Homey, Anja Meuller-Homey -- Angiogenesis inhibition in cancer therapy / Iris Appelmann ... [et al.] -- Vascular integrins : therapeutic and imaging targets of tumor angiogenesis / Curzio Ruegg, Gian Carlo Alghisi -- PDGF and vessel maturation / Carina Hellberg, Arne Ostman, C.-H. Heldin -- Lymphangiogenesis in cancer : current perspectives / Rudiger Liersch ... [et al.] -- Compounds in clinical phase III and beyond / Torsten Kessler ... [et al.] -- Metronomic chemotherapy : principles and lessons learned from applications in the treatment of metastatic prostate cancer / Urban Emmenegger ... [et al.] -- Targeting inflammatory cells to improve anti-VEGF therapies in oncology / Hans-Peter Gerber, Ezogelin Olazoglu, Iqbal S. Gerwal -- Antibody-based vascular tumor targeting / Christoph Schliemann, Dario Neri -- Caveolae and cancer / Kerri A. Massey, Jan E. Schnitzer.
  • Part I: Angiogenesis in cancer -- Strategies to prolong the nonangiogenic dormant state of human cancer / George N. Naumov and Judah Folkman -- Vascular endothelial growth factor: basic biology and clinical implications / Napoleone Ferrara -- Angiogenesis in solid tumors / Rakesh K. Jain and Dan G. Duda -- Pathophysiologic role of VEGF in hematologic malignancies / Klaus Podar ... [et al.] -- Tumor microenvironment and angiogenesis / Cheryl H. Baker and Isaiah J. Fidler -- Part II: Targeting angiogenesis for cancer therapy -- Tyrosine kinase inhibitors of angiogenesis / Janessa J. Laskin and Alan B. Sandler -- Development of antiangiogenic monoclonal antibodies for cancer therapy / Zhenping Zhu and Daniel J. Hicklin -- Targeting fibroblast growth factor / fibroblast growth factor receptor system in angiogenesis / Marco Rusnati and Marco Presta -- Development of the VEGF trap as a novel antiangiogenic treatment currently in clinical trials for cancer and eye diseases, and discovery of the next generation of angiogenesis targets / John S. Rudge ... [et al.] -- Proteinases and their inhibitors in angiogenesis / Yves A. DeClerck, Khalid Bajou, and Walter E. Laug -- Prostaglandins and COX-2: role in antiangiogenic therapy / Kristin Hennenfent, Daniel Morgensztern, and Ramaswamy Govindan -- Integrins, adhesion, and coadhesion inhibitors in angiogenesis / Abebe Akalu and Peter C. Brooks -- Conventional therapeutics with antiangiogenic activity / Christian Hafner, Thomas Vogt, and Albrecht Reichle -- Vascular disrupting agents / David J. Chaplin, Graeme J. Dougherty, and Dietmar W. Siemann -- Vascular and hematopoietic stem cells as targets for antiangiogenic therapy / Carlos Almeida Ramos, Hans-Georg Kopp, and Shahin Rafii -- Genetic strategies for targeting angiogenesis / Anita Tandle, Mijung Kwon, and Steven K. Libutti -- Identification of new targets using expression profiles / Thomas R. Burkard ... [et al.].; Part III: Translating angiogenesis inhibitors to the clinic -- Clinical trial design and regulatory issues / Ramzi N. Dagher and Richard Pazdur -- Surrogate markers for antiangiogenic cancer therapy / Darren W. Davis -- Noninvasive surrogates / Bruno Morgan and Mark A. Horsfield -- Pharmacodynamic markers in tissues / Darren W. Davis -- Blood-based biomarkers for VEGF inhibitors / Amado J. Zurita, Hua-Kang Wu, and John V. Heymach -- Part IV: Treatment of specific cancers with angiogenesis inhibitors -- Antiangiogenic therapy for colorectal cancer / Paulo M. Hoff and Everardo D. Saad -- Combined modality therapy of rectal cancer / Christopher G. Willett and Dan G. Duda -- Antiangiogenic therapy for breast cancer / Pablo M. Bedano ... [et al.] -- Antiangiogenic therapy for lung malignancies / David J. Stewart -- Antiangiogenic therapy for prostate cancer / Leslie K. Walker, Glenn Liu, and George Wilding -- Antiangiogenic therapy for hematologic malignancies / Karen W.L. Yee and Francis J. Giles -- Antiangiogenic therapy for gliomas / Heinrich Elinzano and Howard A. Fine -- Antiangiogenic therapy for Kaposi's sarcoma / Henry B. Koon, Liron Pantanowitz, and Bruce J. Dezube -- Antiangiogenic therapy for melanoma / Keith Dredge and Angus G. Dalgleish -- Sunitinib and renal cell carcinoma / Robert J. Motzer and Sakina Hoosen.
  • The concept of delivering 'magic bullets' to treat diseases was first proposed by Paul Erlich in the early 1900's. The realization of this concept for the treatment of cancer occurred in the late 1990's with the approval of monoclonal antibody therapies. The use of monoclonal antibodies conjugated (linked) to potent cytotoxic agents (antibody-drug conjugates, ADCs) for specifically delivering cytotoxics to cancer cells was an obvious extension of antibody-based therapy. ADCs have been under intense investigation for several decades; progress, however, has been limited due to toxicity or lack of improved efficacy compared to unconjugated cytotoxics. More recently, linker technology and target selection have advanced such that several ADCs and immunotoxins are undergoing clinical testing or are approved for use. This important volume gives the latest and most comprehensive information on the topic, describing different types of ADCs and immunotoxins for both hematologic and solid malignancies. Finally, the volume highlights the promise that this technology holds for diverse types of human cancer.
  • "This book covers clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. The second edition includes drugs that are currently in development. In addition, the text emphasizes the applications of synthetic and medicinal chemistry to the preparation of analogs with enhanced activities. Contributors also address the potential of novel drug discovery through the use of genome mining as well as the status of advanced development candidates. For each compound of class of compounds, the text provides information on the history, structure, mechanism of action, development, synthesis, medicinal chemistry, and clinical applications"-- Provided by publisher."The search for new lead compounds is a crucial element of modern pharmaceutical research. Natural products provided the only source of pharmaceuticals for thousands of years, and natural products have made enormous contributions to human health through compounds such as quinine, morphine, aspirin (a natural product analog), digitoxin, and many others. The potential of natural products as anticancer agents was recognized in the 1950's by the U. S. National Cancer Institute (NCI) under the leadership of the late Dr. Jonathan Hartwell, and the NCI has since made major contributions to the discovery of new naturally occurring anticancer agents through its contract and grant support, including an important program of plant and marine collections. Many, although not all, of the compound classes described in the following pages owe their origin in whole or in part to NCI support. In spite of the success of the natural products approach to anticancer drug discovery, as exemplified by the following chapters, in recent years their importance as a source of molecular diversity for drug discovery research and development has been overshadowed by newer chemical approaches currently in favor. These approaches include chemical ones which make heavy use of combinatorial chemistry, and biological ones such as manipulation of biosynthetic pathways of microbial metabolites through combinatorial biosynthetic techniques. It is thus worthwhile to review briefly the major reasons why natural products are so important. First, there is a strong biological and ecological rationale for plants and marine invertebrates to produce novel bioactive secondary metabolites"-- Provided by publisher.
  • Anticancer drug development 2002, ScienceDirect
    A brief history of cancer chemotherapy -- Novel targets in the cell cycle and cell cycle checkpoints -- Growth factor and signal transduction targets for cancer therapy -- Cell death pathways as targets for anticancer drugs -- Drug resistance pathways as targets -- Role of matrix metalloproteinases and plasminogen activators in cancer invasion and metastasis: therapeutic strategies -- Tumor vasculature as a target -- Gene-directed enzyme prodrug therapy -- Tumor antigens as targets for anticancer drug development -- Structure-based drug design and its contributions to cancer chemotherapy -- The contribution of synthetic organic chemistry to anticancer drug development -- Biosynthetic products for anticancer drug design and treatment: the bryostatins -- DNA-encoded peptide libraries and drug discovery -- Mechanism-based high-throughput screening for novel anticancer drug discovery -- Tumor cell cultures in drug development -- Screening using animal systems -- Relevance of preclinical pharmacology and toxicology to Phase I trial extrapolation techniques: relevance of animal toxicity -- Clinical trial design: incorporation of pharmacokinetic, pharmacodynamic, and pharmacogenetic principle -- Tumor imaging applications in the testing of new drugs -- Mechanistic approaches to Phase I clinical trials.
  • History of drug discovery : early evaluation studies and lessons learnt from them / Ahmad, Z., Makaya, N.H. and Grosset, J. -- Tuberculosis treatment trials past and present : old and new challenges / Nunn, N. -- The rifamycins : renewed interest in an old drug class / Burman, W., Dooley, K.E., and Nuermberger, E. -- Isoniazid pharmacokinetics and efficacy in adults and children / Donald, P.R. and Schaaf, H.S. -- Recent developments in the study of pyrazinamide : an update / Mitchison, D.A. and Zhang, Y. -- Experience with phase III clinical trials of antituberculosis drugs and regimens : conclusions and lessons for the future / Jindani, A. -- Tuberculosis recurrence : exogenous or endogenous? / Williams, M. ... [et al.] -- Second-line antituberculosis drugs : current knowledge, recent research findings and controversies / Schaaf, H.S., Seddon, J.A., and Caminero, J.A. -- Acquisition, transmission, and amplification of drug-resistant tuberculosis / Müller, B. ... [et al.] -- The treatment of tuberculosis in children -- Cruz, A.T. and Starke, J.R. -- Issues and challenges in the development of novel tuberculosis drug regimens / Erondu, N. and Ginsberg, A. -- Drug resistance in mycobacterium tuberculosis : molecular mechanisms and laboratory susceptibility testing / Bittger, E.C. -- The role of the mouse model in the evaluation of new antituberculosis drugs / Nuermberger, E.L. -- Current issues in tuberculosis pharmacokinetics / Egelund, E.F. and Peloquin, C.A. -- Pharmacological considerations of antitubercular agents in children / Goldman, J.L., Kearns, G.L., and Abdel-Rahman, S.M. -- Interactions between antituberculosis and antiretroviral agents / Mcilleron, H. and Khoo, S.H. -- Diabetes mellitus and tuberculosis treatment / Ruslami, R., Van Crevel, R. -- Early bactericidal activity of antituberculosis agents / Maritz, J.Z., Diacon, A.H., and Donald, P.R. -- Assessment of whole-blood bactericidal activity in the evaluation of new antituberculosis drugs / Wallis, R.S. -- Serial sputum colony counting in drug regimens / Sloan, D. and Davies, G. -- The evaluation of new antituberculosis drugs in children / Mcneeley, D.F. ... [et al.] -- A new era in tuberculosis treatment : what does the future hold? / Duncan, K.
  • APC proteins 2009, Springer
    APC and [beta]-catenin degradation -- Nuclear APC -- APC in cell migration -- The APC-EB1 interaction -- The role of APC in mitosis and in chromosome instability -- Role of APC and its binding partners in regulating microtubules in mitosis -- The adenomatous polyposis coli tumor -- Suppressor and Wnt signaling in the regulation of apoptosis -- APC and its modifiers in colon cancer -- Tissue-specific tumour suppression by APC -- Extra-colonic manifestations of familial adenomatous polyposis coli.
  • Apoptosis and cancer 2008, Springer Protocols
    Modulation of apoptosis to reverse chemoresistance /Gil Mor,Michele K. Montagna,andAyesha B. Alvero - -Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis /Suparna Mazumder,Dragos Plesca,andAlexandru Almasan - -Flow cytometry enumeration of apoptotic cancer cells by apoptotic rate /David Diaz... [et al.] - -Detection of cancer-related proteins in fresh-frozen ovarian cancer samples using laser capture microdissection /Dan-Arin Silasi... [et al.] - -Flow cytometric detection of activated caspase-3 /Richard FoxandMartine Aubert - -The chemofx® assay : an ex vivo chemosensitivity and resistance assay for predicting patient response to cancer chemotherapy /Stacey L. Brower,Jeffrey E. Fensterer,andJason E. Bush --Correlation of caspase activity and in vitro chemo-response in epithelial ovarian cancer cell lines /Ayesha B. Alvero,Michele K. Montagna,andGil Mor - -Assessing expression of apoptotic markers using large cohort tissue microarrays /Elah Pick,Mary M. McCarthy,andHarriet M. Kluger --Mitochondria potential, bax "activation," and programmed cell death /C. Michael KnudsonandNicholas M. Brown --In vitro and in vivo apoptosis detection using membrane permeant fluorescent-labeled inhibitors of caspases /Brian W. Lee... [et al.] - -Caspase activity assays /Andrew L. Niles,Richard A. Moravec,andTerry L. Riss - -Multiplex caspase activity and cytotoxicity assays /Andrew L. Niles,Richard A. Moravec,andTerry L. Riss - -Homogeneous, bioluminescent proteasome assays /Martha A. O'Brien... [et al.] - -A simple method for profiling mirna expression /Jia-Wang WangandJin Q. Cheng - -Apoptotic caspase activation and activity /Jean-Bernard DenaultandGuy S. Salvesen - -Biochemical analysis of the native trail death-inducing signaling complex /Henning WalczakandTobias L. Haas - -Laser microdissection sample preparation for RNA analyses /Christopher J. Vega.
  • v. 2, 2007 Springer
    BCR-ABL and human cancer / Maria Pérez-Caro and Isidro Sánchez-Garcia -- Angiogenesis and cancer / Yohei Maeshima -- Metastasis: the evasion of apoptosis / Christine E. Horak ... [et al.] -- Carcinogenesis: balance between apoptosis and survival pathways / Dean G. Tang and James P. Kehrer -- Aberrations of DNA damage checkpoints in cancer / Marikki Laiho -- c-Myc, apoptosis, and disordered tissue growth / Michael Khan and Stella Pelengaris -- Role of lysophospholipids in cell growth and survival / Xianjun Fang and Sarah Spiegel -- Alternative use of signaling by the [beta] GBP cytokine in cell growth and cancer control: from surveillance to therapy / Livio Mallucci and Valerie Wells -- Control nodes linking the regulatory networks of the cell cycle and apoptosis / Baltazar D. Aguda, Wee Kheng Yio, and Felicia Ng -- Regulation of NF-[kapa]B function: target for drug development / Daniel Sliva and Rakesh Srivastava -- 5-fluorouracil: molecular mechanisms of cell death / Daniel B. Longley and Patrick G. Johnston -- Apoptosis-inducing cellular vehicles for cancer gene therapy: endothelial and neural progenitors / Gergely Jarmy ... [et al.] -- Apoptosis and cancer therapy / Maurice Reimann and Clemens A. Schmitt -- Coupling apoptosis and cell division control in cancer: the survivin paradigm / Dario C. Altieri -- Clinical significance of histone deacetylase inhibitors in cancer / Sharmila Shankar and Rakesh K. Srivastava.
  • The intrinsic pathway of apoptosis -- The extrinsic pathway of apoptosis -- Evaluating the importance of apoptosis and other determinants of cell death and survival -- Mitotic catastrophe -- Autophagy and autophagic cell death -- Regulation and function of detachment-induced cell death (anoikis) in cancer progression and metastasis -- Structure and function of the telomere -- Overview of senescence -- Contributions of telomerase to tumorigenesis -- The role of telomeres in genomic instability -- Overview of the DNA damage checkpoint: ATM and ATR -- Interactions between myc- and cyclin-dependent kinase inhibitors in cancer -- Interplay between [gamma]H2AX and 53BP1 pathways in DNA double-strand break repair response -- DNA-dependent protein kinase in repair, apoptosis, telomere maintenance, and chemotherapy -- Resistance/signaling pathways -- Ceramide and multidrug resistance -- Chemo- and radiosensitization through inhibition of PI3K/Akt signaling -- The advancement of epidermal growth factor receptor inhibitors in cancer therapy -- Antimetabolites -- Topoisomerase I poisons and apoptotic topoisomerase I-DNA complexes -- Perturbations of cellular functions by topoisomerase II inhibitors: all roads lead to cell death? -- The significance of poly-targeting in apoptosis induction by alkylating agents and platinum drugs -- Contributions of apoptosis and senescence to cytotoxicity produced by microtubule-stabilizing agents -- Tyrosine kinase inhibitors -- Monoclonal antibodies in lymphomas -- Role of apoptosis in anti-angiogenic cancer therapies -- Photodynamic therapy-induced apoptosis -- Modulation of TRAIL signaling for cancer therapy.
  • Apoptosome 2010, Springer
  • Ch. 1. Cancer terminator viruses and approaches for enhancing therapeutic outcomes -- Ch. 2. Adenovirus strategies for tissue-specific targeting -- Ch. 3. Syrian hamster as an animal model to study oncolytic adenoviruses and to evaluate the efficacy of antiviral compounds -- Ch. 4. Design of improved oncolytic adenoviruses -- Ch. 5. The development of transcription-regulated adenoviral vectors with high cancer-selective imaging capabilities -- Ch. 6. Adenovirus-based immunotherapy of cancer, promises to keep -- Ch. 7. Cancer treatment with gene therapy and radiation therapy -- Ch. 8. Oncolytic adenoviruses for cancer immunotherapy, data from mice, hamsters, and humans -- Index.
  • Aromatase inhibitors 2006, Springer
  • Atlas of Brain and Spine Oncology Imaging presents a comprehensive visual review of pathologic disease variations of cancers of the brain and spine through extensive radiologic images. The focus of the book is on algorithmic strategies for identifying neoplastic pathologies commonly found in brain and spinal tumors through a visual representation of the variety of appearances that each neoplasm takes, within both benign and malignant manifestations.
  • The Atlas of Genitourinary Oncological Imaging presents a comprehensive visual review of appearances for normal anatomy and oncological diseases in the genitourinary system using over 900 radiological images and illustrations. The book presents current imaging techniques and discusses the role of imaging in pre-treatment staging and post-treatment follow-up. Diseases discussed include kidney, adrenal gland, upper tract, bladder, prostate, testes, and pediatric malignancies. Individual chapters include normal anatomy, imaging techniques, and pathology of each cancer type. The staging of the malignancy and what to include in the radiology report are discussed, and expected and complicated postoperative and post-treatment findings and recurrence are presented. Dedicated chapters on interventional and radiation therapy discuss their unique role in the management and treatment of oncology of the genitourinary system. Additionally, a chapter on chemotherapy toxicities discusses drug reaction treatment therapies unique to the genitourinary system.Edited and written by radiologists from the genitourinary disease management team at Memorial Sloan-Kettering Cancer Center, the Atlas of Genitourinary Oncological Imaging is an ideal resource for radiology and urology trainees seeking a review of the basics and for practicing radiologists looking for answers to challenging cases confronted in daily practice.
  • Male genital disorders represent a common issue in medical practice, especially in the dermatological setting. Correct clinical evaluation of these disorders is essential when addressing the diagnosis, which in some cases may require histopathological confirmation. Depending on the disease, early diagnosis may be not only lifesaving, but also of fundamental importance to the planning of successful treatment. This atlas introduces the most common penile diseases, along with more rarely encountered ones. It provides invaluable guidance on clinical diagnosis by highlighting prominent clinical features and presenting particular videodermatoscopy findings when these are indicative of the diagnosis. In addition, for each condition the most appropriate treatment is proposed, taking into account recent therapeutic advances of proven benefit.
  • Anatomy of the breast -- Techniques and positioning in mammography -- An approach to mammographic analysis -- Circumscribed masses -- Indistinct and spiculated masses -- Analysis of calcification -- Prominent ductal patterns -- Asymmetry and architectural distortion -- The thickened skin pattern -- The axilla -- The male breast -- The postsurgical breast -- The augmented breast -- Galactography -- Needle localization -- Percutaneous breast biopsy -- The roles of ultrasound and magnetic resonance imaging in breast imaging.
  • Lymphangiomatosis -- Pleuropulmonary blastoma -- Congenital pulmonary myofibroblastic tumor -- Alveolar adenoma -- Uncommon endobronchial surface tumors -- Mucous gland adenoma -- Pleomorphic adenoma -- Mucoepidermoid tumor -- Adenoid cystic carcinoma -- Inflammatory polyps -- Inflammatory pseudotumor -- Pulmonary chondroma -- Pulmonary hamartoma -- Localized fibrous tumor -- Lipomas and liposarcomas -- Cystic lymphangioma -- Lymphangioleiomyomatosis -- Epithelioid hemangioendothelioma -- Pulmonary artery sarcoma -- Synovial sarcoma -- Marginal zone B-cell lymphoma (maltoma) -- Diffuse large B-cell lymphoma -- Lymphomatoid granulomatosis -- Langerhans cell histiocytosis -- Typical and atypical carcinoids -- Teratoma -- Melanoma -- Thymoma -- Glomus tumor of the lung -- Sclerosing hemangioma -- Preinvasive disease -- Squamous cell carcinoma -- Adenocarcinoma -- Large cell carcinoma -- Small cell carcinoma -- Adenosquamous carcinoma -- Bronchioloalveolar carcinoma -- Large cell neuroendocrine carcinoma -- Sarcomatoid carcinoma -- Pulmonary blastoma -- Metastatic tumors.
  • Part 1. Pilocytic astrocytoma and Pilomyxoid Astrocytoma -- Pilocytic astrocytoma and Pilomyxoid Astrocytoma / Christine Fuller and Sonia Narendra -- Pleomorphic Xanthoastrocytoma / Christine E. Fuller -- Infiltrative Astrocytomas (Diffuse Astrocytoma, Anaplastic Astrocytoma, Glioblastoma) / Christine E. Fuller -- Oligodendroglial Tumors / Christine E. Fuller -- Ependymal Tumors / Christine E. Fuller, Sonia Narendra and Ioana Tolicica -- Introduction and Overview of Brain Tumors / Adekunle M. Adesina -- Part 2. Embryonal Neuroepithelial Tumors -- Central Nervous System Primitive Neuroectodermal Tumors and Medulloepithelioma / Adekunle M. Adesina, J. Hunter and L. Rorke-Adams -- Medulloblastoma / Adekunle M. Adesina and J. Hunter -- Atypical Teratoid Rhabdoid Tumor / Adekunle M. Adesina, J. Hunter and L. Rorke-Adams -- Part 3. Tumors of the Meninges -- Meningiomas / Christine Fuller and Brian Pavlovitz -- Hemangiopericytoma and Other Mesenchymal Tumors / Christine E. Fuller -- Melanocytic Lesions / Christine E. Fuller -- Hemangioblastoma -- Christine E. Fuller -- Part 4. Tumors of Cranial and Spinal Nerves -- Schwannoma / Tarik Tihan -- Neurofibroma / Tarik Tihan -- Malignant Peripheral Nerve Sheath Tumors / Tarik Tihan -- Part 5. Neuronal and Mixed Neuronal-glial Tumors -- Desmoplastic Infantile Astrocytoma and Ganglioglioma / Adekunle M. Adesina -- Dysembryoplastic Neuroepithelial Tumor / Adekunle M. Adesina and Ronald A. Rauch -- Ganglioglioma and Gangliocytoma / Adekunle M. Adesina and Ronald A. Rauch -- Central Neurocytoma and Extraventricular Neurocytoma / Adekunle M. Adesina and Ronald A. Rauch -- Papillary Glioneuronal Tumor / M. Rivera-Zengotita, A. Illner and Adekunle M. Adesina -- Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle / M. Rivera-Zengotita and Adekunle M. Adesina -- Malignant Epithelioid Glioneuronal Tumor / M. Rivera-Zengotita, R. Rauch and Adekunle M. Adesina -- Paraganglioma / A. Rivera and Adekunle M. Adesina -- Part 6. Neurocutaneous Syndromes -- Neurofibromatosis 1 / Tarik Tihan -- Neurofibromatosis 2 / Tarik Tihan -- Von Hippel-Lindau Disease / Tarik Tihan and Adekunle M. Adesina -- Tuberous Sclerosis Complex / Tarik Tihan and Adekunle M. Adesina -- L'hermitte-Duclos Disease and Cowden Disease / T. Hidehiro, S. Hiroyoshi and Adekunle M. Adesina -- Part 7. Tumors in the Region of the Pituitary Fossa -- Pituitary Tumors / Tarik Tihan and Christine E. Fuller -- Craniopharyngioma / Tarik Tihan -- Part 8. Choroid Plexus Neoplasms -- Choroid Plexus Neoplasms / Christine E. Fuller, Sonia Narendra and Ioana Tolocica -- Part 9. Pineal Based Tumors -- Pineal Parenchymal Tumors / Tarik Tihan -- Part 10. Germ Cell Tumors -- Germ Cell Tumors / Tarik Tihan -- Part 11. Paraneoplastic Disorders -- Paraneoplastic Disorders of the Central Nervous System / Christine E. Fuller and Sonia Narendra -- Part 12. Tumours of the Haematopoietic System -- Malignant Lymphoma / Adekunle M. Adesina -- Histiocytic Tumors / A. Mukherjee and Adekunle M. Adesina -- Part 13. Interesting/Challenging Cases and Exercises in Pattern Recognition -- Case Studies / Adekunle M. Adesina, Christine E. Fuller and Lucy Rocke-Adams.
  • This new project on PET/MR imaging in oncology includes digital interactive software matching the cases in the book. The interactive version of the atlas is based on the latest web standard, HTML5, ensuring compatibility with any computer operating system as well as a dedicated version for Apple iPad and iPhone. The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illustrated clinical case reports are then presented. Each case study includes a short clinical history, findings, and teaching points, followed by illustrations, legends, and comments. The multimedia version of the book includes dynamic movies that allow the reader to browse through series of rotating 3D images (MIP or volume rendered), display blending between PET and MR, and dynamic visualization of 3D image volumes. The movies can be played either continuously or sequentially for better exploration of sets of images. The editors of this state-of-the-art publication are key opinion leaders in the field of multimodality imaging. Professor Osman Ratib (Geneva) and Professor Markus Schwaiger (Munich) were the first in Europe to initiate the clinical adoption of PET/MR imaging. Professor Thomas Beyer (Zurich) is an internationally renowned pioneering physicist in the field of hybrid imaging. Individual clinical cases presented in this book are co-authored by leading international radiologists and nuclear physicians experts in the use of PET and MRI.
  • Atlas of skin cancers 2011, Springer
  • Soft tissue tumors are a large and heterogeneous group of tumors and pseudotumors with a spectrum of behavior from benign to frankly malignant. This Atlas of Soft Tissue Tumor Pathology provides an overview of reactive, pseudoneoplastic, benign and intermediate neoplasms, sarcomas and related conditions arising in subcutaneous and deep soft tissues. Emphasis is placed on microscopic appearances with correlation with gross diagnostic findings where relevant. In addition, the immunohistochemical and molecular genetic features of the major soft tissue tumor subtypes are presented.
  • Atlas of thyroid lesions 2011, Springer
    Physical and technical essentials -- Ultrasound features of thyroid lesions -- Nodular or colloid goiter, hyperplasia, and cysts -- Follicular adenoma and follicular thyroid carcinoma -- Oncocytic nodule/Hurtle cell tumors -- Follicular variant of papillary thyroid carcinoma -- Papillary thyroid carcinoma -- Medullary thyroid carcinoma -- Anaplastic carcinoma -- Lymphoma and plasmacytoma -- Thyroiditis -- Metastases -- Regional lymph node metastases.
  • Autophagy and cancer 2013, Springer
    This book covers the latest advances in the field of autophagy and cancer from the basics of the molecular machinery for autophagy induction and regulation up to current areas of interest, including modulation of autophagy and drug discovery for cancer prevention and treatment. The reader will be initially introduced to the historical context of autophagy, followed by a summary of the key players in autophagy, a discussion on the origin of autophagosomes, and an overview of signal transduction regulation of autophagy. The next chapters deal with the complex relationship between autophagy and tumorigenesis through in-depth discussions of how autophagy influences cell survival, apoptosis, inflammation, immunity, tumor microenvironment, metabolic stress, DNA damage, and genomic instability. The remaining chapters discuss how autophagy affects cancer cell response to therapy and how to best modulate autophagy for therapeutic benefit - what to target and how to target. We hope that this monograph will be an invaluable reference source for professionals, students, postdoctoral fellows, and senior scientists working in the fields of autophagy and cancer.
  • Bacteria and cancer 2012, Springer
  • Basic radiation oncology 2010, Springer
    Radiation physics -- Radiobiology -- Clinical radiation oncology -- Central nervous system tumors -- Head and neck cancers -- Lung cancer -- Breast cancer -- Genitourinary system cancers -- Gynecological cancers -- Gastrointestinal system cancers -- Soft tissue sarcoma -- Skin cancer -- Lymphomas and total body irradiation.
  • Basics of oncology 2009, Springer
  • BCL-2 protein family 2010, Springer
    Homeostatic functions of BCL-2 proteins beyond apoptosis / Nika N. Danial, Alfredo Gimenez-Cassina, and Daniel Tondera -- Alternative functions of the BCL-2 protein family at the endoplasmic reticulum / Diego Rojas-Rivera ... [et al.] -- BH3-only proteins and their effects on cancer / Thanh-Trang Vo and Anthony Letai -- Endoplasmic reticulum stress and BCL-2 family members / Ross T. Weston and Hamsa Puthalakath -- Targeting survival pathways in lymphoma / Luca Paoluzzi and Owen A. O'Connor -- The interplay between BCL-2 family proteins and mitochondrial morphology in the regulation of apoptosis / Maria Eugenia Soriano and Luca Scorrano -- Noncanonical functions of BCL-2 proteins in the nervous system / Heather M. Lamb and J. Marie Hardwick -- Mitochondria on guard : role of mitochondrial fusion and fission in the regulation of apoptosis / Mariusz Karbowski.
  • Sect. 1. Head and neck. Head and neck cancer / Barbara A. Conley ... [et al.] -- Sect. 2. Thorax. Non-small cell lung cancer / Anne M. Horgan and Oscar S. Breathnach -- Small cell lung cancer / Neelima Denduluri and Martin E. Gutierrez -- Sect. 3. Digestive system. Esophageal cancer / Gregory D. Leonard, David P. Kelsen, and Carmen J. Allegra -- Gastric cancer / M. Wasif Saif -- Biliary tract cancer / Gregory D. Leonard, Eileen M. O'Reilly, and Carmen J. Allegra -- Primary cancers of the liver / Gregory D. Leonard, William R. Jarnagin, and Carmen J. Allegra -- Colorectal cancer / George P. Kim, Chris H. Takimoto, and Carmen J. Allegra -- Pancreatic cancer / George P. Kim, James L. Gulley, Chris H. Takimoto -- Anal cancer / M. Wasif Saif -- Other gastrointestinal tumors / M. Wasif Saif -- Sect. 4. Breast. Breast cancer / Hamid R. Mirshahidi and Jame Abraham -- Sect. 5. Genitourinary. Renal cell cancer / Hung T. Khong, Christopher Klebanoff, and Susan Bates --Prostate cancer / James L. Gulley and William L. Dahut -- Bladder cancer / Manish Agarwal and William L. Dahut -- Testicular carcinoma / Avi S. Retter and Barnett S. Kramer -- Sect. 6. Gynecologic. Ovarian cancer / Eddie Reed and Ramin Altaha -- Endometrial cancer / Christina M. Annunziasta and Michael J. Birrer -- Cervical cancer / Edwin M. Posades and Herbert L. Kotz -- Vulvar cancer / Christina M. Annunziasta and Michael J. Birrer -- Sect. 7. Musculoskeletal. Sarcomas and malignancies of the bone / Patrick J. Mansky and Lee Helman -- Sect. 8. Skin cancer. Skin cancers and melanoma / Upendra P. Hegde and Barry Gause -- Sect. 9. Hematologic malignancies. Acute leukemias / Michael Craig, Jame Abraham, and Brian P. Monahan -- Chronic leukemias / Muzaffar H. Quazilbash and Michael J. Keating -- Chronic myeloid leukemia / Muzaffar H. Quazilbash and Jorge E. Cortes -- Myeloproliferative diseases / Manish Monga and Marcel P. Devetten --Multiple myeloma / Sattva S. Neelapu and Cynthia E. Dunbar -- Non-Hodgkin lymphoma / Martin Gutierrez, Richard F. Little, and Wyndham H. Wilson -- Hodgkin lymphoma / Gisa Schun, Jame Abraham, and Marcel P. Devetten -- Hematopoietic stem cell transplantation / Michael Craig, Jame Abraham, and Richard W. Childs -- Sect. 10. Other malignancies. Acquired immunodeficiency syndrome-related malignancies / Pallavi P. Kumar and Richard F. Little -- Carcinoma of unknown primary / Hung T. Khong -- Central nervous system tumors / Patrick J. Mansky, J. Paul Duic, and Howard A. Fine -- Endocrine tumors / Michael E. Menefee and Tito Fojo -- Sect. 11. Supportive care. Hematopoietic growth factors / Philip M. Arlen and James L. Gulley -- Infectious complications in oncology / Sarah M. Wynne and Juan C. Gea-Banacloche -- General principles of cancer pain management / Jason R. Beckrow and Richard A. Messmann --Oncologic emergencies and paraneoplastic syndromes / Muhammad K. Siddique and Richard A. Messmann -- Psychopharmacologic management in oncology / Donald L. Rosenstein, Maryland Pao, and June Cai -- Management of emesis in oncology / David R. Kohler -- Nutrition for oncology patients / Marnie Dobbin -- End-of-life care / Jane Carter -- Sect. 12. Targeted treatments and complimentary and alternative medicine. Targeted therapies / James L. Gulley and Gregory Curt -- Complementary and alternative medicine in oncology / Patrick J. Mansky, Dawn b. Wallerstedt, and Marc R. Blackman -- Sect. 13. Common procedures and chemotherapy drugs. Central venous access devices / Deborah C. Gutierrez and Naomi P. O'Grady -- Procedures in medical oncology / Suzanne G. Demko and Kerry Ryan -- Anticancer agents / Thomas E. Hughes.
  • Monitoring the burden of cancer in the United States -- Cancer biology and nutrigenomics -- Cellular cancer processes and their molecular targets -- Nutrigenetics: the relevance of polymorphisms -- Diet and epigenetics -- Nutrient signaling-protein kinase to transcriptional activation -- Dietary energy balance, calorie restriction, and cancer prevention -- Fiber and microbially generated active components -- Gut microbiota, probiotics, prebiotics and colorectal cancer -- Meats, protein and cancer -- Saturated fatty acids and cancer -- Conjugated linoleic acid and cancer -- Cancer and n-3PUFAs: the translational connection -- n-6 polyunsaturated fatty acids and cancer -- Carotenoids -- Vitamin A -- Vitamin D and cancer chemoprevention -- Folate -- Selenium -- Calcium and cancer -- Iron and cancer -- Zinc in cancer development and prevention -- Cruciferous vegetables, isothiocyanates, indoles, and cancer prevention -- Garlic and cancer prevention -- Mammary and prostate cancer chemoprevention and mechanisms of action of resveratrol and genistein in rodent models -- Cancer prevention by catechins, flavonols, and procyanidins -- Mechanisms of action of isoflavones in cancer prevention -- The anticarcinogenic properties of culinary herbs and spices -- Cancer prevention with berries: role of athocyanins -- Pomegranate -- Alcohol and cancer: biological basis -- Aryl hydrocarbon receptor-mediated carcinogenesis and modulation by dietary xenobiotic and natural ligands -- Opportunities and challenges for communicating food and health relationships to American consumers.
  • The emergence of bioinformatics : historical perspective, quick overview and future trends / Christos A. Ouzounis -- The statistical design and interpretation of microarray experiments / Kevin K. Dobbin and Richard M. Simon -- Whole-genome analysis of cancer / Steven A. Enkemann ... [et al.] -- Bioinformatics approaches to the analysis of the transcriptome of animal models of cancer / Mark J. Hoenerhoff ... [et al.] -- Significance of aberrant expression of miRNAs in cancer cells / George A. Calin ... [et al.] -- Proteomic methods in cancer research / Scot Weinberger and Egisto Boschetti -- Comprehensive genomic profiling for biomarker discovery for cancer detection, diagnostics and prognostics / Xiaofeng Zhou ... [et al.] -- Gene expression profiling of the leukemias : oncogenesis, drug responsiveness, and prediction of clinical outcome / Lars Bullinger, Hartmut Dohner, and Jonathon R. Pollack -- Personalized medicine in the clinical management of colorectal cancer / Anthony El-Khoueiry and Heinz Josef Lenz -- PIK3CA gene alterations in human cancers / Sérgia Velho, Carla Oliveira, and Raquel Seruca.
  • Biology of oral cancer 2014, CRCnetBASE
    "Cancer is a class of disease or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues. One new approach in dealing with cancer is through apoptotic regulators, which is the process of controlling cell growth by abnormally prolonging cell survival, facilitating the accumulation of transforming mutations and promoting resistance. This book uses oral cancers as the specific means to demonstrate this technique with this particular type of cancer, which is quite prevalent (and deadly) in India and other parts of Asia, in particular"--Provided by publisher.
  • Guidelines for the design of clinical studies for the development and validation of therapeutically relevant biomarkers and biomarker-based classification systems / Richard M. Simon -- Analytical aspects of biomarker immunoassays in cancer research / C. G. J. (Fred) Sweep, Chris M. G. Thomas and Manfred Schmitt -- Tissue microarrays: state-of-the-art, pitfalls, and promises / Chungyeul Kim and Soonmyung Paik -- Gene expression profiling with DNA microarrays / Michele De Bortoli and Nicoletta Biglia -- Assays for gene amplification / Chungyeul Kim, Yongkuk Song, and Soonmyung Paik -- Cell kinetics / Maria Grazia Daidone, Rosella Silvestrini, and Dino Amadori -- Urokinase-type plasminogen activator and PAI-1 / Michael J. Duffy -- Predictive value of c-erbb-2 for endocrine therapy and chemotherapy in breast cancer / Vered Stearns -- Erb-b-2 as a therapeutic target / Robert Mass -- The epidermal growth factor receptor pathway as a selective -- Molecular-targeting treatment in human breast cancer / Fortunato Ciardiello, Teresa Troiani, and Giampaolo Tortora -- P-53 as a prognostic and predictive indicator / Daniela Kandioler and Raimund Jakesz -- Occult metastatic cells in breast cancer patients / Stephan Braun, Julia Seeber, and Christian Marth -- Circulating HER-2/neu / Allan Lipton ... [et al.] -- Circulating vascular endothelial growth factor / Roberta Sarmiento ... [et al] -- Detection of early tumor dissemination in patients with breast cancer / Debra Hawes and Richard J. Cote -- New technologies/new markers/new challenges / Daniel F. Hayes and Giampietro Gasparini -- Index.
  • Biomarkers in oncology 2013, Springer
  • Biosensors and cancer 2013, CRCnetBASE
    Functional optical imaging-based biosensors / Pablo Iglesias and Jose A. Costoya -- Use of a surface plasmon resonance (SPR) biosensor to characterize zwitterionic coatings on SiO2 for cancer biomarker detection / Norman D. Brault, Shaoyi Jiang, and Qiuming Yu -- Microcantilever-based biosensor array for tumor angiogenic marker detection / Riccardo Castagna and Carlo Ricciardi -- Electrochemical DNA biosensors at the nanoscale / Rosa Letizia Zaffino ... [et al.] -- Aptamer-based biosensors for cancer studies / Ilaria Palchetti and Marco Mascini -- Fluorescent biosensors for cancer cell imaging and diagnostics / May C. Morris -- Electrical and electrochemical immunosensor for cancer study / Seung Yong Lee and Seung Yong Hwang -- Multifunctional nanobiosensors for cancer / Dai-Wen Pang and Er-Qun Song -- Silicon nanowire biosensor for cancer markers / Yang-Kyu Choi and Chang-Hoon Kim -- DNA-electrochemical biosensors and oxidative damage to DNA : application to cancer / Victor Constantin Diculescu and Ana Maria Oliveira Brett -- Asparaginase-based asparagine biosensors and their application to leukemia / Neelam Verma and Kuldeep Kumar -- Breast cancer detection using surface plasmon resonance-based biosensors / Chii-Wann Lin and Chia-Chen Chang -- Detection of miRNA with silicon nanowire biosensors / Guo-Jun Zhang -- Biosensors for BCR-ABL activity and their application to cancer / Yusuke Ohba ... [et al.] -- Optical fiber nanobiosensor for single living cell detections of cancers / Xin Ting Zheng and Chang Ming Li -- Microfluidic biosensors for thyroglobulin detection and application to thyroid cancer / Seokheun Choi and Junseok Chae -- Optical biosensors and applications to drug discovery and development in cancer research / Carlo Bertucci and Angela De Simone -- Single-chain fragment variable recombinant antibodies and their applications in biosensors for cancer diagnosis / Xiangqun Zeng and Ray Mernaugh -- DNA biosensor for rapid detection of anticancer drugs / Sigen Wang and Ruili Wang -- Using UV light to engineer biosensors for cancer detection : the case of prostate specific antigen / Maria Teresa Neves-Petersen, Antonietta Parracino, and Steffen B. Petersen.
  • Biosimilars 2013, Springer
    Biologicals' Characteristics / K. Ho and J.-H. Trouvin --From the Biosimilar Concept to the Marketing Authorisation / M. Pavlovic and J.-L. Prugnaud --Immunogenicity / J.-L. Prugnaud --Substitution and Interchangeability / J.-L. Prugnaud --G-CSFs: Onco-Hematologist's Point of View / D. Kamioner --The Oncologist's Point of View / C. Chouaïd --Biosimilars: Challenges Raised by Biosimilars: Who is Responsible for Cost and Risk Management? / F. Megerlin.
  • Central Nervous System Tumors /Paolo Aloisi, Francesco Martella, Davide Cerone and Giampiero Porzio --Head and Neck Tumours /Keith D. Hunter and Robert Bolt --Thyroid Cancer /Laura D. Locati, Angela Greco, Maria Grazia Borrello, Maria Luisa Carcangiu and Paolo Bossi, et al. --Targeted Therapies for Non-small-Cell Lung Cancer /Giulio Metro and Lucio Crinò --Non-Hodgkin's Lymphomas /Roberta Zappasodi and Massimo Di Nicola --Leukemias /Lia Ginaldi and Massimo De Martinis --Breast Cancer /Nadia Rucci, Luca Ventura and Anna Teti --Oesophago-Gastric Cancer /Alex M. Reece-Smith, Simon L. Parsons and Sue A. Watson --Colorectal Cancer /David N. Church, Rachel Susannah Midgley and David J. Kerr --Hepatocellular Carcinoma /Yasunori Minami and Masatoshi Kudo --Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma /Laura S. Schmidt --Bladder Cancer /Andrea Tubaro, Daniele Santini, Cosimo De Nunzio, Alice Zoccoli and Michele Iuliano --Biomarkers in Prostate Cancer /Mauro Bologna and Carlo Vicentini --Ovarian Cancer /Jessica Wangui Oribabor, Allison Ambrosio, Cesar M. Castro and Michael J. Birrer --Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer /Annekathryn Goodman, Leslie S. Bradford and Leslie A. Garrett --Biotargets in Sarcomas: The Past, Present, and a Look into the Future /Vivek Subbiah and Razelle Kurzrock --Melanoma and Other Skin Cancers /Kim H. T. Paraiso, Jobin K. John and Keiran S. M. Smalley --Molecular Pathology of Cancer Metastasis: Suggestions for Future Therapy /Adriano Angelucci and Edoardo Alesse --Current and Future Developments in Cancer Therapy Research: miRNAs as New Promising Targets or Tools /Marilena V. Iorio, Patrizia Casalini, Claudia Piovan, Luca Braccioli and Elda Tagliabue.
  • Bladder cancer 2010, Springer
  • Bladder tumors 2011, Springer
  • Blasenkarzinom 2005, Springer
  • Bone and cancer 2009, Springer
  • Bone cancer. 1st ed. 2010, ScienceDirect
    Chapter 1. Epidemiology of Primary Bone Tumors and Economical Aspects of Bone Metastases / Esther I. Hauben, Pancras C.W. Hogendoorn -- Chapter 2. Tumor-Bone Cell Interactions in Bone Metastases / Pierrick G.J. Fournier, Lauren K. Dunn, Gregory A. Clines, Theresa A. Guise -- Chapter 3. Early Bone Metastasis-Associated Molecular and Cellular Events / Philippe Clézardin -- Chapter 4. Regulation of Osteoblast Differentiation and Bone Cancers by Wnt and PTH Signaling Pathways / Julia Billiard, John A. Robinson, Ramesh A. Bhat, Bheem M. Bhat, Richard J. Murrills, Peter V.N. Bodine -- Chapter 5. Osteoclast Differentiation and Function / Luis Filgueira -- Chapter 6. Immunoregulation of Osteoclast Differentiation in Multiple Myeloma Bone Disease / Maria Grano, Giacomina Brunetti, Silvia Colucci -- Chapter 7. Facts and Hypothesis on Osteolytic Lesions Related to Normal and Tumoral Epithelial Dental Cell Differentiation / Blandine Ruhin, Frédéric Lézot, Aymann Bouattour, Sonia Ghoul-Mazgar, Ariane Berdal, Vianney Descroix -- Chapter 8. The Role of the Interleukin-6 Family of Cytokines in Bone Remodeling and Bone Cancer / Frédéric Blanchard, Emmanuelle David, Bénédicte Brounais -- Chapter 9. Proteases and Therapeutic Approaches of Bone Tumors / Velasco C. Ruiz, Y. Fortun, D. Heymann, M. Padrines -- Chapter 10. Bone Remodeling Markers and Bone Cancer / Markus J. Seibel -- Chapter 11. Cytogenetic and Molecular Genetic Alterations in Bone Tumors / Suvi Savola, Tom Böhling, Sakari Knuutila -- Chapter 12. Cytogenetics of Bone Tumors / Jiyun Lee, Mallory Martin, Shibo Li -- Chapter 13. Genetic Aspects of Bone Tumors / Shamini Selvarajah, Maria Zielenska, Jeremy A. Squire, Paul C. Park -- Chapter 14. Proteomics of Bone Cancer / Stephanie Byrum, Eric R. Siegel, Sudeepa Bhattacharyya, Larry J. Suva -- Chapter 15. Genomic and Proteomic Profiling of Osteosarcoma / Tsz-Kwong Man, Pulivarthi H. Rao, Ching C. Lau -- Chapter 16. Molecular Pathology of Osteosarcoma / Walter C. Bell, Gene P. Siegal -- Chapter 17. Technical Aspects: How Do We Best Prepare Bone Samples for Proper Histological Analysis? / Daniel Chappard -- Chapter 18. Osteoclast-rich Lesions of Bone: A Clinical and Molecular Overview / Adrienne M. Flanagan, Roberto Tirabosco, Panagiotis D. Gikas -- Chapter 19. Recent Advances in the Biology of Bone Tumors and New Diagnostic Tools / Gonzague de Pinieux, Corinne Bouvier -- Chapter 20. Ewing's Sarcoma Family of Tumors / Joseph D. Khoury -- Chapter 21. The Histopathology of Skeletal Metastases / Ping Tang, David G. Hicks --Chapter 22. Interventional Radiologic Techniques and their Contribution to the Management of Bone Tumors / Robert G. Jones, Eric J. Heffernan, Faisal Rashid, Peter L. Munk -- Chapter 23. Imaging of Bone Metastases / Nieroshan Rajarubendra, Nathan Lawrentschuk -- Chapter 24. Diagnosis of Skeletal Metastases in Malignant Extraskeletal Cancers / Holger Schirrmeister, Coskun Arslandemir -- Chapter 25. Pain Control with Palliative Radiotherapy in Bone Metastases / Alysa Fairchild, Amanda Hird, Edward Chow -- Chapter 26. Mechanisms and Management of Bone Cancer Pain / Ma'ann C. Sabino, Denis R. Clohisy -- Chapter 27. Malignant Skeletal Pain: Mechanisms and Potential Therapeutic Opportunities / Monica Herrera, Juan Miguel Jimenez-Andrade, Marina Vardanyan, Patrick W. Mantyh -- Chapter 28. Animal Models of Malignant Primary Bone Tumors and Novel Therapeutic Approaches / Julie Rousseau, François Lamoureux, Gaëlle Picarda, François Gouin, Valérie Trichet, Françoise Rédini -- Chapter 29. In vivo Models Used in Studies of Bone Metastases / Ingunn Holen, Michelle A. Lawson -- Chapter 30. Cytokine Gene Therapy in Bone Remodeling / Carl D. Richards, David Smyth -- Chapter 31. Non-surgical Treatment of Chondrosarcoma: Current Concepts and Future Perspectives / Eric L. Staals, Emanuela Palmerini, Stefano Ferrari, Mario Mercuri -- Chapter 32. Mechanistic Role of RANKL in Cancer-induced Bone Diseases and Development of a Targeted Therapy to Inhibit this Pathway / William C. Dougall -- Chapter 33. Chondrosarcoma of Bone: Diagnosis and Therapy / Arne Streitbuerger, Jendrik Hardes, Georg Gosheger -- Chapter 34. Current Status of Immunotherapy for Osteosarcoma and its Future Trends / Kanji Mori, Kosei Ando, Yoshitaka Matsusue, Dominique Heymann -- Chapter 35. Bisphosphonates, Bone Health and the Clinical Biology of Bone Metastases from Breast Cancer / Alexander H.G.Paterson -- Chapter 36. A Multi-targeted Approach to Treating Bone Metastases / Robert D. Loberg, Kenneth J. Pienta -- Chapter 37. Bone Metastases of Prostatic Cancer: Pathophysiology, Clinical Complications, Actual Treatment and Future Directions / Sara De Dosso, Fernanda G. Herrera, Dominik R. Berthold -- Chapter 38. Apoptosis and Drug Resistance in Malignant Bone Tumors / Udo Kontny.
  • 1.New Insights in the Development of Human B Lymphocytes /Bianca Blom --2.The Aging Lymphocyte /Hector F. Valenzuela, Rita B. Effros --3.The Bone Marrow Microenvironment and Its Impact in Acute and Chronic B Cell Malignancies /Jan A. Burger --4.The Expanding Diagnostic Role of Flow Cytometry in Bone Marrow Studies of Patients with Lymphomas and Plasma Cell Disorders /Anna Porwit --5.The Application of Molecular Techniques on Bone Marrow Trephines /Falko Fend, Leticia Quintanilla-Martínez --6.Residual Disease Assessment and Its Role in Monitoring Lymphoid and Plasma Cell Neoplasms /Konnie M. Hebeda --7.Reporting of Bone Marrow Lymphoid Infiltrates /Yi-Hua Chen, LoAnn Peterson --8.Janus-Faced Lymphoid Infiltrates /Dimitra Anagnostou --9.Singularities in Pediatric Bone Marrow Lymphoid Processes /Sophia L. Yohe, Robert W. McKenna --10.Bone Marrow Involvement in Primary Mature B and T Cell Leukemias /Ayoma D. Attygalle --11.A Step Forward in the Diagnosis of B-Cell Lymphomas in the Bone Marrow /Ahmet Dogan, Mine Hekimgil --12.New Insights in Waldenström's Macroglobulinemia /Meletios A. Dimopoulos, Evangelos Terpos --13.Bone Marrow in Hodgkin Lymphoma and Mimickers /Stefano A. Pileri, Elena Sabattini --14.Misleading Features of Bone Marrow Involvement by Peripheral T-Cell Lymphomas /Philippe Gaulard, Sylvia Hoeller --15.Systemic Mastocytosis Associated with Lymphoproliferative Disorders (SM-AHNMD) /Hans-Peter Horny, Karl Sotlar, Peter Valent.
  • Bone metastasis 2005, Springer
    Overview / Sadmeet Singh and Gurmit Singh -- Parathyroid hormone-related peptide and malignancy / David Goltzman -- Vitamin D and vitamin D analogs in cancer / Richard Kremer and Shafaat A. Rabbani -- Role of TGF and IGF in tumor progression and bone metastases / Erin Giles and Gurmit Singh -- Biologic and therapeutic implications of osteomimicry and epithelial/mesenchymal transition in prostate cancer / Wen-Chin Huang, Valerie Odero-Marah, and Leland W.K. Chung -- The roles of immune-cell derived matrix metalloproteinases in tumor growth and metastasis / Kristina A. Szabo and Gurmit Singh -- Contribution of osteopontin to the development of bone metastasis / Alison L. Allan ... [et al.] -- The role of interleukin-11 in osteolytic bone metastasis / Ryan R. Simon ... [et al.] -- Cell adhesion moleculars in tumor metastasis / Sujata Persad ... [et al.] --Antithrombotics in tumor growth and metastasis / Shaker A. Mousa -- Challenges and strategies in the analysis of multiple events in oncology / Pierre P. Major and Richard J. Cook -- Integrins : novel targets for the treatment of bone metastasis / Graham C. Parry ... [et al.] -- Bone metastasis and pathological fractures : bone tissue engineering as a novel therapy / Laurie A. McDuffee, Nigel Colterjohn, and Gurmit Singh -- Role of photodynamic therapy for bone metastasis / Shane Burch and Albert J.M. Yee -- Docetaxel for metastatic cancer and its role in combination therapies for advanced prostate cancer / Ellen K. Wasan ... [et al.] -- The use of tetracyclines for bone metastasis / Eric Seidlitz, Zeina Saikali, and Gurmit Singh -- Role of bisphosphonates in skeletal metastases / Arif Hussain and Fred Saad -- Radiation treatment of bone metastases / Edward Chow, Jackson Wu, and Elizabeth Toni Barnes.
  • Bone sarcoma 2013, Springer
    Multidisciplinary approach to the management of sarcomas of bone /Bryan S. Moon --Bone sarcoma imaging /John E. Madewell ... [et al.] --Percutaneous image-guided biopsy for diagnosis of bone sarcomas /Kamran Ahrar --Orthopedic oncologic surgical specimen management and surgical pathology /A. Kevin Raymond and Alexander J. Lazar --Osteosarcoma /Patrick P. Lin and Shreyaskumar Patel --Ewing sarcoma /Patrick P. Lin ... [et al.] --Chondrosarco /Alan W. Yasko, Vinod Ravi, and Ashleigh Guadagnolo --Rare bone sarcomas /Valerae O. Lewis ... [et al.] --Skeletal reconstruction after bone sarcoma resection /Christopher P. Cannon and David W. Chang --Soft tissue reconstruction after bone sarcoma resection /Scott D. Oates --Bone sarcomas in the growing child /Valerae O. Lewis and David W. Chang --Perioperative management of patients with bone sarcomas /Janie Rutledge, Mark S. Pilarczyk, and Alan W. Yasko --Rehabilitation in orthopedic oncology /Benedict Konzen and Christopher P. Cannon --Follow-up evaluation and surveillance after treatment of bone sarcomas /Colleen M. Costelloe and Patrick P. Lin.
  • Bone tumors 2012, Springer
    Introduction to Bone Tumors --How to Evaluate a Bone Lesion --Imaging Modalities --Cartilage Tumors --Osseous Tumors --Fibrous Tumors --Miscellaneous Tumors --Bone Metastases --Bone Tumor Mimickers --Cases.
  • Brain cancer 2010, Springer
  • Brain metastases 2007, Springer
  • Brain tumor pathology 2006, Springer
  • Brain tumors 2005, Springer
    Epidemiology of brain tumors / Randa El-Zein, Melissa Bondy, and Margaret Wrensch -- Molecular genetics of tumors of the central nervous system / C. David James -- Molecular pathology of nervous system tumors / Catherine L. Nutt ... [et al.] -- Genetic modeling of glioma formation in mice / Martin Begemann ... [et al.] -- Biology of brain metastasis / Minsoo Kang ... [et al.] -- Analysis of neural precursor cells in the context of origin of brain tumors, their treatment, and repair of treatment-associated damage / Mark Noble and Joerg Dietrich -- Biology of primitive neuroectodermal tumors / John R. Hill, Shoichiro Ohta, and Mark A. Israel -- Molecular and cellular biology of the blood-brain barrier and its characteristics in brain tumors / Helga E. de Vries ... [et al.] -- Immune regulation in the brain : lessons from autoimmunity and implications for brain tumor therapy / Lois A. Lampson -- Genetic pathways in the evolution of gliomas / Hiroko Ohgaki and Paul Kleihues -- DNA damage and repair in the therapeutic response of tumors of the central nervous system / Henry S. Friedman, M. Eileen Dolan, and Francis Ali-Osman -- Role of urokinase-type plasminogen activator receptor in human glioma invasion / Sanjeeva Mohanam and Jasti S. Rao -- Regulation of the cell cycle and apoptosis in human brain tumors / Juan Fueyo, Candelaria Gomez-Manzano, and Timothy J. McDonnell -- Systemic chemotherapy for metastatic tumors of the central nervous system / Charles A. Conrad and W.K. Alfred Yung -- Radiation biology and therapy of tumors of the central nervous system / Nalin Gupta ... [et al.] -- Advances in the management of cerebral metastases / Fadi Hanbali and Raymond Sawaya -- Immunotherapy of central nervous system tumors: contemporary cancer research / Amy B. Heimberger ... [et al.] -- Targeting drugs to tumors of the central nervous system / Maciej S. Lesniak, James Frazier, and Henry Brem -- Rational design and development of targeted brain tumor therapeutics / Francis Ali-Osman ... [et al.].
  • Brain tumors. 3rd ed. / 2011, ScienceDirect
    Meet the increasing need for effective brain tumor management with the highly anticipated revision of Brain Tumors by Drs. Andrew H. Kaye and Edward R. Laws. Over the past decade, enormous advances have been made in both the diagnosis and the surgical and radiotherapeutic management of brain tumors. This new edition guides you through the latest developments in the field, including hot topics like malignant gliomas, functional brain mapping, neurogenetics and the molecular biology of brain tumors, and biologic and gene therapy. You'll also have easy access to the complete contents online, with links to PubMed and a downloadable image library, at www.expertconsult.com. Benefit from the knowledge and experience of Drs. Andrew H. Kaye and Edward R. Laws, globally recognized experts in the field of neurosurgery, as well as many other world authorities.
  • Burden of Breast and Gynecological Cancers in Low-Resource Countries -- Breast Cancer: Pathology, Cytology, and Core Needle Biopsy Methods for Diagnosis -- Gynecological Cancers: Pathology and Cytological Methods for Diagnosis of Gynecological Cancers -- Screening and Early Diagnosis of Breast Cancer: Proven Methodology and an Optimized Strategy for Developing Countries -- HPV and Cervical Cancer -- Screening for Cervical Cancer in Low-Resource Countries -- Ovarian Cancer Screening and Early Detection in Low- and Middle-Income Countries -- Endometrial Cancer: Risk Factors and Early Diagnosis in Low-Resource Countries -- Breast and Gynecologic Cancer Prevention in Low-Resource Countries -- Combined Screening for Breast and Gynecological Cancers Using Mobile Clinics: The Barretos Experience (Brazil) -- Cost-Effectiveness of Screening for and Early Diagnosis of Breast and Gynecological Cancers in Low-Income Countries -- Challenges for Breast and Gynecological Cancer Control by Early Detection in Less-Developed Countries -- Funding for Global Healthcare Intervention: Initiatives Aimed at Controlling Cancer in Women in Low-Resource Countries -- Coordinated Training on Early Detection and Diagnosis of Breast Cancer Across Different Levels of Health Workers: An Example from Peru -- Telemedicine in Cancer Control Programs in Developing Countries -- Breast Cancer Screening and Cervical Cancer Prevention in Developing Countries: Strategies for the Future -- Well Woman Clinic Concept: An Integrated Approach for Screening and Early Diagnosis of Breast and Gynecological Cancers in Developing Countries.
  • Breast cancer 2008, Springer
  • Breast cancer 2011, Springer
    The theory of the sick lobe -- Lobar anatomy of human breast and its importance for breast cancer -- Breast cancer may originate in utero: the importance of the intrauterine environment for breast cancer development -- Genetic alterations in normal and malignant breast tissue -- The role of ductal lavage: a cautionary tale -- The distribution of the earliest forms of breast carcinoma -- The implications of the imaging manifestations of multifocal and diffuse breast cancers -- Lobar ultrasound of the breast -- The lobar distribution of the lesions in breast carcinoma: ductoscopy and surgery -- Strop breast cancer now!: imagining imaging pathways towards search, destroy, cure, and watchful waiting of premetastasis breast cancer -- Epilogue: the diseased breast lobe in the context of X-chromosome inactivation and differentiation waves.
  • Overview -- Common benign conditions of low concern -- Benign conditions associated with a risk for the subsequent development of cancer -- Precursor lesions and noninvasive cancers -- Breast cancer -- Things pathologists must always consider -- Nuances and details of the pathology report.
  • Overview of resistance to systemic therapy in patients with breast cancer / Ana Maria Gonzalez-Angulo, Flavia Morales-Vasquez and Gabriel N. Hortobagyi -- Roles of multidrug resistance genes in breast cancer chemoresistance / M. Tien Kuo -- Therapy-induced apoptosis in primary tumors / David J. McConkey -- Cell cycle deregulation in breast cancer: insurmountable chemoresistance or achilles' heel? / Laura Lambert and Khandan Keyomarsi -- p53, BRCA1 and breast cancer chemoresistance / Kimberly A. Scata and Wafik S. El-Deiry -- Integrin-mediated adhesion: tipping the balance between chemosensitivity and chemoresistance / Mary M. Zutter --Insulin-like growth factors and breast cancer therapy / Xianke Zeng and Douglas Yee -- EGF receptor in breast cancer chemoresistance / Robert B. Dickson and T.B. Deb -- Molecular mechanisms of ErbB2-mediated breast cancer chemoresistance / Ming Tan and Dihua Yu -- Estrogen receptors in resistance to hormone therapy / Matthew H. Herynk and Suzanne A.W. Fuqua -- Novel approaches for chemosensitization of breast cancer cells: the E1A story / Yong Liao, Dihua Yu and Mien-Chie Hung.
  • Global burden of breast cancer / Jacques Ferlay ... [et al.] -- Breast cancer biology and clinical characteristics / Amanda I. Phipps and Christopher I. Li -- In situ breast cancer / Brian L. Sprague and Amy Trentham-Dietz -- Endogenous hormones / Amanda I. Phipps and Christopher I. Li -- Exogenous hormones / Christopher I. Li and Elisabeth F. Beaber -- Reproductive factors / Mats Lambe -- Physical activity and anthropometric factors / Katherine D. Henderson, Jennifer Prescott, and Leslie Bernstein -- Diet and nutrition / Martin Lajous and Shumin M. Zhang -- Environmental and occupational exposures / Amanda I. Phipps ... [et al.] -- Shift work and circadian disruption / Scott Davis and Dana K. Mirick -- Non-hormonal medications and chronic diseases / Patricia F. Coogan -- Male breast cancer / Ian S. Fentiman -- Inherited predisposition: familial aggregation and high risk genes / Kathleen E. Malone and Kerryn W. Reding -- Common genetic susceptibility loci / Mikkel Z. Oestergaard and Paul Pharoah -- Mammographic density as a potential surrogate marker for breast cancer / Norman F. Boyd, Lisa J. Martin, and Salomon Minkin -- Breast cancer screening / Karla Kerlikowske -- Principles of breast cancer therapy / Allison W. Kurian and Robert W. Carlson -- Breast cancer outcomes / Graham A. Colditz and Courtney Beers.
  • Burden of breast cancer in developing and developed countries -- Genetics of breast cancer in women of African Descent: an overview -- Biology of breast cancer: molecular and pathologic features of ductal neoplasia of the breast: racial considerations -- Screening and early detection of breast cancer in women in Africa and the Middle East -- Breast cancer at diagnosis in women of Africa and the Middle East -- Breast cancer aggressiveness in women of African descent -- Radiotherapy of breast cancer -- Adjuvant therapy of breast cancer -- Endocrine therapy of breast cancer -- Palliative care for breast cancer in the African-American population -- Outcome of African American women with breast cancer in cooperative group clinical trials -- Traditional medicine in breast cancer management with a focus on the Chinese integrative approach -- Impact of culture, education and socio-economic status -- Barriers to successful management of breast cancer.
  • Breast cancer research protocols 2005, Springer Protocols
    Breast tissue banking: collection, handling, storage, and release of tissue for breast cancer research / Linda Snell and Peter H. Watson -- Frozen biopsy collection and storage: frozen biopsy samples / Russell Leek -- Serial biopsies/fine-needle aspirates and their assessment / Irene Boeddinghaus and Stephen R.D. Johnson -- Breast tissue microarrays / Robert J. Springall and Cheryl E. Gillett -- Preparation of tumor homogenates for subsequent preparation of cytosols, membrane fractions, RNA, and DNA / Naomi Robertson and Russell Leek -- Isolation of RNA from tumor samples: single-step guanidinium acid-phenol method / Naomi Robertson and Russell Leek -- Isolation of DNA from tumor samples / Naomi Robertson and Russell Leek -- Laser-assisted microdissection and isolation of DNA and RNA / Ulrich Lehmann and Hans Kreipe --Fluorescence in situ hybridization and comparative genomic hybridization / Patricia Gorman and Rebecca Roylance -- Fluorescence in situ hybridization assessment of c-myc gene amplification in breast tumor tissues / Jan K. Blancato, Mary Steele Williams, and Robert B. Dickson -- Detection of HER2 gene amplification by fluorescence in situ hybridization in breast cancer / John M.S. Bartlett, and Amanda Forsyth -- In situ hybridization combined with immunohistochemistry to localize gene expression / Rosemary Jeffery, Toby Hunt, and Richard Poulsom -- Quantitation of RNA by ribonuclease protection assay / John W. Moore -- Identification of steroid hormone-regulated genes in breast cancer / Bruce R. Westley and Felicity E.B. May -- Sequencing of the tumor suppressor gene TP 53 / Barbro Linderholm, Torbjörn Norberg, and Jonas Bergh -- Expression profiling using cDNA microarrays / Chris Jones ... [et al.] -- Gene expression analysis using filter cDNA microarrays / Peter Simpson ... [et al.] --Immunohistochemistry / Cheryl E. Gillett -- Detection of aberrant glycosylation in breast cancer using lectin histochemistry / Tracey M. Carter and Susan A. Brooks -- SDS-PAGE and western blotting to detect proteins and glycoproteins of interest in breast cancer research / Chloe Osborne and Susan A. Brooks -- Breast cancer proteomics using two-dimensional electrophoresis: studying the breast cancer proteome / Miriam V. Dwek and Sarah L. Rawlings -- Procedures for the quantitative protein determination of urokinase and its inhibitor PAI-1 in human breast cancer tissue extracts using ELISA / Manfred Schmitt ... [et al.] --Methods to analyze the effects of the urokinase system on cancer cell adhesion, proliferation, migration, and signal transduction events / Ute Reuning ... [et al.] -- Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damage / Kum Kum Khanna, Magtouf Gatei, and Gordon Tribbick -- Models of hormone resistance in vitro and in vivo / Jennifer MacGregor Schafer and V. Craig Jordan -- Generation of genetically modified embryonic stem cells for the development of knockout mouse animal model systems / Stephen D. Robinson, Stephen Wilson, and Kairbaan M. Hodivala-Dilke -- In vivo xenograft models of breast cancer metastatsis / Ursula Valentiner, Susan A. Brooks, and Udo Schumacher -- Neoadjuvant endocrine therapy models / Juliette Murray, William R. Miller, and J. Michael Dixon -- Primary mouse endothelial cell culture for assays of angiogenesis / Louise E. Reynolds and Kairbaan M. Hodivala-Dilke.Traditional and established indicators of prognosis and treatment success / Derek E. Roskell and Ian D. Buley -- Sentinel lymph node biopsy in breast cancer / Celia Chao and Kelly M. McMasters -- Pathological evaluation of axillary sentinel lymph nodes in breast cancer / Michael Z. Gilcrease and Aysegul Sahin -- Measurement of estrogen receptor status by immunocytochemistry in paraffin wax sections / Bharat Jasani ... [et al.] -- Markers of apoptosis / Falzul H. Sarkar and Yiwei Li -- Quantitative angiogenesis in breast cancer / Stephen B. Fox --
  • Part I. Prevention -- Risk Factors / Polly A. Newcomb and Karen J. Wernli -- Lifestyle Factors and Risk of Breast Cancer: A Review of Randomized Trial Findings / Garnet L. Anderson -- Breast Cancer Chemoprevention / Mary B. Daly -- Surgical Management of Inherited Susceptibility to Breast Cancer / Francis Freisinger and Susan M. Domchek -- Part II. Early Detection -- Clinical Breast Examination and Breast Self-Examination / William H. Goodson -- Mammography / Barbara C. Cavanaugh and Sorcha McNally -- Current Status and Future Prospects in Breast Carcinoma of Positron Emission Tomography / Sandip Basu, Joshua I. Rosenbaum and Abass Alavi -- Breast MRI / Barbara C. Cavanaugh and Sorcha McNally -- Genetic and Molecular Approaches to Imaging Breast Cancer / Eric Wickstrom and Mathew L. Thakur -- Intraductal Approaches: Nipple Aspirate Fluid to Assist in Breast Cancer Detection / Edward R. Sauter -- Intraductal Approaches: Mammary Ductoscopy and Ductal Lavage to Assist in the Diagnosis of Breast Cancer / William C. Dooley -- Blood Markers / Mark W. Duncan -- Circulating Tumor Cells in Breast Cancer / Michail Ignatiadis and Dimitris Mavroudis.
  • Breast cancer. 2nd ed. 2008, Springer
  • Breast carcinoma 2008, Springer
  • Breast anatomy and basic histology, physiology, and pathology -- A pathologist's overview of the pathology of breast disease / Joseph Rabban -- Epidemiology, etiology, risk factors, and survival from breast cancer -- Screening for breast cancer -- Radiation risk -- Staging breast cancer -- Ductal carcinoma in situ and early-stage breast cancer: detection, diagnosis, and prognostic indicators -- Mammography: equipment and basic physics -- Quality assurance and quality control / Debra Deibel -- Mammographic positioning -- A systematic approach to breast imaging -- Mammography and the normal breast -- Interpreting the mammogram -- Benign lesions -- Probably benign findings appropriately managed with short-interval follow-up --Suspicious lesions and lesions with a high probability of malignancy -- Breast ultrasound -- The altered breast: pregnancy, lactation, abscess, post biopsy changes, mastectomy, radiation, and implants -- The male breast -- Magnetic resonance imaging of the breast / Carol A. Hulka and Daniel B. Kopans -- Evaluating women with lumps, thickening, discharge or pain: imaging women with signs or symptoms that might indicate breast cancer -- Image sequencing: problems and solutions in breast evaluation -- Histological, pathological and imaging correlation -- Interventional procedures in the breast -- The breast imaging report: data management and the breast imaging audit -- The medical-legal problem and breast imaging -- Digital mammography -- Digital breast tomosynthesis -- Cytopathology.
  • Breast MRI 2005, Springer
  • Breast MRI 2008, Springer
  • Pt. 1. Fundamentals -- pt. 2. Biologic principles -- pt. 3. Initial evaluation of the patient -- pt. 4. Common presenting complaints and concerns -- pt. 5. Diagnostic techniques -- pt. 6. Breast cancer overview -- pt. 7. Breast surgery : management of the primary tumor -- pt. 8. Breast surgery : sentinel node biopsy and axillary dissection -- pt. 9. Breast surgery : special issues -- pt. 10. Cytology and pathology -- pt. 11. Systemic therapy for breast cancer -- pt. 12. Radiation therapy of the breast -- pt. 13. The breast cancer survivor.
  • Breast ultrasound 2013, Springer
    Diagnosis of breast cancer: modern aspects -- Technique of breast ultrasound -- Ultrasound of the normal breast -- Ultrasound diagnosis of breast cancer -- Classification of breast masses -- Ultrasound features of different types of breast cancer -- Differential diagnosis of breast diseases -- Age-related changes in breast structure: breast ultrasound in children and adolescents -- Breast pathology in men -- Ultrasound examination of regional lymph nodes -- Ultrasound examination after breast surgery -- Recurrent breast cancer.
  • Burkitt's lymphoma 2013, Springer
  • Mechanism of action of topoisomerase I poisons / Leroy F. Liu and Shyamal D. Desai -- Crystallographic insight into the mechanism of drug-induced topoisomerase I DNA damage / Alex B. Burgin, Jr., Bart L. Staker, and Lance Stewart -- Inhibitors of topoisomerase I function / Sidney M. Hecht -- Cytotoxic mechanisms of the topoisomerase I inhibitors / Yves Pommier ... [et al.] -- Biochemical and genetic analyses of DNA topoisomerase I-mediated DNA damage / Robert C.A.M. Van Waardenburg and Mary-Ann Bjornsti -- Preclinical models for evaluating topoisomerase-I targeted drugs / Aarti S. Juvekar ... [et al.] -- Mechanisms of resistance to camptothecins / Zeshaan A. Rasheed and Eric H. Rubin -- Recent advances in camptothecin drug design and delivery strategies / Thomas G. Burke ... [et al.] -- Clinical experience with 9-aminocamptothecin: lessons for new drug development / Chris H. Takimoto -- Clinical studies of rubitecan (9-nitro 20(s) camptothecin) / Hilary Hewes, Judith A. Smith, and Claire Verschraegen -- Irinotecan: current clinical status and pharmacological aspects / Laurent P. Rivory -- Clinical experience with topotecan / Aimee K. Bence and Val R. Adams -- The clinical development of lurtotecan: experience with water-soluble and liposomal forms / Keith T. Flaherty ... [et al.] -- Preclinical and clinical development of dx-8951f (exatecan mesylate): a hexacyclic camptothecin analog / Eric K. Rowinsky -- Camptothecins in the treatment of primary brain tumors / Clinton F. Stewart, Markos Leggas, and Henry S. Friedman -- Camptothecins in the treatment of lung cancer / Pankaj Kumar ... [et al.] -- Use of camptothecins in the treatment of leukemia and related disorders / Bejamin M.F. Mow and Scott H. Kaufmann.
  • Cancer 2006, Springer
  • Cancer and aging 2013, Karger
    Chronic mechanistic target of rapamycin inhibition : preventing cancer to delay aging, or vice versa? / Sharp, Z.D.; Curiel, T.J.; Livi, C. -- Senescent cells and their secretory phenotype as targets for cancer therapy / Velarde, M.C.; Demaria, M.; Campisi, J. -- Cancer vaccination at older age / Gravekamp, C. -- Immunology of aging and cancer development / Fulop, T. ... [et al.] -- Metabolic syndrome and cancer : from bedside to bench and back / Extermann, M. -- Frailty : a common pathway in aging and cancer / Balducci, L. -- Targeting age-related changes in the biology of acute myeloid leukemia : is the patient seeing the progress? / Vey, N. -- Comprehensive geriatric assessment in oncology / Mohile, S.G.; Magnuson, A. -- Pharmacology of aging and cancer : how useful are pharmacokinetic tests? / Lichtman, S.M. -- Surgery in older cancer patients : recent results and new techniques : worth the investment? / Van Leeuwen, B.L.; Huisman, M.G.; Audisio, R.A. -- Organizing the geriatrician/oncologist partnership : one size fits all? practical solutions / Holmes, H.M.; Albrand, G. -- Geriatric oncology nursing : beyond standard care / Overcash, J. -- Exercise for older cancer patients : feasible and helpful? / Klepin, H.D.; Mohile, S.G. ; Mihalko, S. -- Aging and cancer : addressing a nation's challenge / Brochot, J.-M.; Le Quellec-Nathan, M.; Buzyn, A.
  • 1. Obesity and Cancer Epidemiology -- 2. Obesity and Cancer: Epidemiology in Racial/Ethnic Minorities -- 3. Obesity and Cancer in Asia -- 4. Genetic Epidemiology of Obesity and Cancer -- 5. Obesity and Cancer: Overview of Mechanisms -- 6. Caloric Restriction and Cancer -- 7. Physical Activity and Cancer -- 8. Energy Balance, Cancer Prognosis, and Survivorship -- 9. Behavior, Energy Balance, and Cancer: An Overview -- 10. Geographic and Contextual Effects on Energy Balance-Related Behaviors and Cancer.
  • Cancer and IgE 2010, Springer
  • Cancer and pregnancy 2008, Springer
  • Cancer and sexual health 2011, Springer
  • Peyton Rous: A Centennial Tribute to the Founding Father of Cancer Virology --Viruses and Cancer: A Historical Perspective - HBV and Prevention of a Cancer --Virus-Mediated Cell Proliferation --Viral-Encoded Genes and Cancer --Oncogenic Viruses and Cancer Transmission --DNA Viruses and Cancer: Taking a Broader Look --Herpesviruses and Cancer --Lymphocryptoviruses: EBV and Its Role in Human Cancer --Nonhuman Primate Gamma-herpesviruses and Their Role in Cancer --Rhadinoviruses: KSHV and Associated Malignancies --Retroperitoneal Fibromatosis Herpesvirus and Kaposi's Sarcoma-Like Tumors in Macaques --Murine Gammaherpesvirus-Associated Tumorigenesis --Marek's Disease Virus-Induced T-Cell Lymphomas --Polyomaviruses and Cancer --Polyomavirus SV40: Model Infectious Agent of Cancer --BK Polyomavirus and Transformation --Polyomavirus JC and Human Cancer: Possible Role of Stem Cells in Pathogenesis --Merkel Cell Polyomavirus --Human Papillomaviruses and Cancer --Tumorigenesis by Adenovirus Type 12 E1A --Overview of Hepatitis Viruses and Cancer --Hepadnaviruses and Hepatocellular Carcinoma --Hepatitis C Virus and Hepatocellular Carcinoma --Human and Animal Retroviruses: HIV-1 Infection Is a Risk Factor for Malignancy --HTLV-1 and Oncogenesis --Human T-Cell Leukemia Virus Type 2 (HTLV-2) Biology and Pathogenesis --Mechanisms of Oncogenesis by Avian and Murine Retroviruses --Rous Sarcoma Virus: Contributions of a Chicken Virus to Tumor Biology, Human Cancer Therapeutics, and Retrovirology --Mouse Mammary Tumor Virus and Cancer --Jaagsiekte Sheep Retrovirus and Lung Cancer --Small RNAs and Their Role in Herpesvirus-Mediated Cancers --Viral Malignancies in HIV-Associated Immune Deficiency.
  • Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology, but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis, and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers, and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer.
  • Cancer cell culture 2004, Springer Protocols
  • Cancer cell signaling 2002, Springer Protocols
  • Clinical strategies for cancer treatment: the role of drugs -- Target identification and drug discovery -- Clinical drug development and marketing approval -- Principles of pharmacokinetics -- Delivering anticancer drugs to brain tumors -- Pharmacogenetics -- Physical barriers to drug delivery -- Antifolates -- 5-fluoropyrimidines -- Cytidine analogues -- Purine antimetabolites -- Hydroxyurea -- Antimitotic drugs -- Alkylating agents -- Platinum analogues -- Bleomycin and other antitumor antibiotics -- Topoisomerase I-targeting drugs -- Topoisomerase II inhibitors: anthracyclines -- Topoisomerase II inhibitors: the epipodophyllotoxins -- Asparaginase -- Proteasome inhibitors -- Histone deacetylase inhibitors in oncology -- Differentiating agents -- Arsenic trioxide -- Antibodies -- Inhibitors of tumor angiogenesis -- Epidermal growth factor receptor inhibitors -- HER2 inhibitors -- Molecular targeted drugs -- Signaling inhibitors: IGFR, PI3K pathway, embryonic signaling inhibitors, and mitotic kinase inhibitors -- Cytokine therapy for cancer -- Cancer vaccines -- Adoptive cellular therapies -- Thalidomide and its analogs in the treatment of hematologic malignancies, including multiple myeloma, and solid tumors -- Hormonal therapy of breast cancer -- Hormone therapy for prostate cancer -- Drug therapy of pain in cancer patients -- Hematopoietic growth factors -- Antinausea medications -- Bisphosphonates and other bone-targeted therapies -- Intravenous access and catheter management -- Late effects of cancer chemotherapy -- Infertility after cancer chemotherapy.
  • A simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience. The first part of this book is unique in explaining the recent developments in the field in terms of their point of action in the natural history of cancer. The second and third sections contain a more straightforward description of practical aspects of chemotherapy, and the current place of drug treatment in everyday cancer management, including the outcomes of that treatment.
  • Cancer clinical trials 2007, Springer
    Historical perspective and evolving concerns for human research / Bernard Lo and Nesrin Garan -- Cancer trials and the Institutional Review Board (IRB) / Scott Kurtzman and Zita Lazzarini -- NCI's cancer therapy evaluation program: a commitment to treatment trials / Jeffrey S. Abrams, Anthony Murgo and Michaele C. Christian -- Practical guide for cancer clinical investigators / Steven Hirschfeld -- The role of cooperative groups in cancer clinical trials / Ann M. Mauer, Elizabeth S. Rich and Richard L. Schilsky -- The advocate role in clinical study development and partnering with patient advocates in your local institution / Barbara Parker -- The National Breast Cancer Coalition: setting the standard for advocate collaboration in clinical trials / Fran Visco -- The role of the principal investigator in cancer clinical trials / Stanley P.L. Leong -- The audit process and how to ensure a successful audit / Y. Nancy You, Lisa Jacobs, Elizabeth Martinez and David M. Ota -- The privacy rule (HIPAA) as it relates to clinical research / John M. Harrelson and John M. Falletta -- The Commission on Cancer, American College of Surgeons' response to HIPAA / E. Greer Gay -- Ethical and legal issues in the conduct of cancer clinical trials / Gerianne J. Sands and Peggy A. Means -- The role of the Office of Research Integrity in cancer clinical trials / Peter Abbrecht, Nancy Davidian, Samuel Merrill and Alan R. Price -- Strategies for the administration of a clinical trial infrastructure: lessons from a comprehensive cancer center / Leonard A. Zwelling and Carleen A Brunelli -- The clinical research process: building a system in harmony with its users / Greg Koski -- Cancer research and clinical trial in action: an important exercise before you embark on your study / Stanley P.L. Leong, Larry Carbone and Scott Kurtzman.
  • Cancer drug resistance 2006, Springer
  • Cancer epidemiology v. 1-2, 2009, Springer Protocols
    v. 2, 2009 Springer Protocols
    v. 1. Host susceptibility factors -- v. 2. Modifiable factors.
  • Cancer epigenetics 2009, CRCnetBASE
    The role of epigenetics in cancer / Trygve O. Tollefsbol -- DNA hypomethylation in cancer / Peter L. Molloy -- DNA hypermethylation in oncogenesis / J. Tyson DeAngelis ... [et al.] -- Imprinting alterations in tumorigenesis / Jeremiah Bernier-Latmani and Phillip Shaw -- Proteins that modulate DNA methylation aberrations in cancer / Sabrina L. Walthall ... [et al.] -- The role of DNA methylation in cancer progression / Sang-Woon Choi and Simonetta Friso -- Alterations in histone acetylation in tumorigenesis / Sabita N. Saldanha and Trygve O. Tollefsbol -- Histone methylation and the initiation of cancer / Shi Huang -- The role of sirtuins in aging and tumorigenesis / Xiaohong Zhang ... [et al.] -- Proteins that alter histone modifications in cancer / Ada Ao and Jianrong Lu -- Dietary and environmental influences on histone modifications in cancer / Sabita N. Saldanha ... [et al.] -- Noncoding RNAs in cancer / Maciej Szymanski and Jan Barciszewski -- Cancer-linked DNA hyper- and hypomethylation: chromosome positional effects / Melanie Ehrlich -- Chromatin remodeling and cancer / Sari Pennings and Richard R. Meehan --Poly-ADP-ribosylation in cancer / Rajeshwar N. Sharan -- Polycomb group proteins in tumorigenesis / Hanneke E.C. Niessen and Jan Willem Voncken -- Cancer and aging: the epigenetic connection / Craig A. Cooney -- DNA methylation in tumor diagnosis / Kavitha Ramachandran, Edna Gordian, and Rakesh Singal -- DNA methylation profiles as prognostic markers for cancer / Sam Thiagalingam and Panagiotis Papageorgis -- Diagnosing cancer using histone modification analysis / Mukesh Verma and Deepak Kumar -- Histone modifications in cancer biology and prognosis / Matthew A. McBrian, David B. Seligson, and Siavash K. Kurdistani -- Histone deacetylase inhibitors in cancer therapy / Aaron M. Sargeant ... [et al.] -- Methylation changes in neoplasia: diagnostic and therapeutic implications / Eleftheria Hatzimichael, Justin Stebbing, and Tim Crook -- Clinical trials and approved drugs for epigenetic cancer therapy / Debby M.E.I. Hellebrekers and Manon van Engeland -- Future directions in epigenetic cancer research / Jacob Peedicayil.
  • Cancer gene therapy 2005, Springer
    Cancer gene therapy : historical perspective / Malcolm K. Brenner -- The genetic basis of cancer / Akseli Hemminki and Kari Hemminki -- Tumor suppressor gene replacement for cancer / Jack A. Roth and Susan F. Grammer -- Antisense technology / Ruiwen Zhang and Hui Wang -- Cancer therapeutic applications of ribozymes and RNAi / Lisa Scherer and John J. Rossi -- Fusogeneic membrane glycoproteins for cancer gene therapy : a better class of killer / Andrew Bateman ... [et al.] -- Suicide gene therapy / Caroline J. Springer and Ion Niculescu-Duvaz -- Molecular chemotherapy approaches / Daniel H. Palmer and David J. Kerr -- Genetic immunotherapy approaches / Denise R. Shaw and Albert F. LoBuglio -- Immunotherapy of cancer by dendritic cell-targeted : gene transfer / Tanja D. de Gruijl, Herbert M. Pinedo, and Rik J. Scheper -- Dendritic cells / Weiping Zou, Shuang Wei and Tyler J. Curiel --Polynucleotide immunization for cancer therapy / Theresa V. Strong -- Development of oncolytic replication-competent herpes simplex virus vectors: the G207 paradigm / Tomoki Todo and Samuel D. Rabkin -- Development of oncolytic adenoviruses : from the lab bench to the bedside / John A. Howe, Robert Ralston, and Murali Ramachandra -- Conditionally replicating adenoviruses for cancer treatment / Ramon Alemany -- Reovirus as an oncolytic agent / Megan K. Patrick, Kara L. Norman, and Patrick W. K. Lee -- Antiangiogenic gene therapy of cancer / Steve Gyorffy ... [et al.] -- Proapoptotic strategy in cancer gene therapy / David H. Holman ... [et al.] -- Antimetastasis / Duen-Hwa Yan, Kung-Ming Rau, and Mien-Chie Hung -- Antimetastatic gene therapy : prostate cancer theory to therapy / Thomas A. Gardner ... [et al.] --Drug-resistance gene transfer as an antitumor strategy / Colin L. Sweeney and R. Scott McIvor -- Chemosensitization / Per Eystein Lønning -- Radiosensitization by gene therapy / Steven J. Chmura, Michael Garofalo, and Ralph R. Weichselbaum -- Nonviral vector systems for cancer gene therapy / Greg F. Walker and Ernst Wagner -- Viral vectors for cancer gene therapy / Joanne T. Douglas and David T. Curiel -- Bacterial systems for tumor-specific gene therapy / J. Martin Brown ... [et al.] -- Molecular imaging of cancer gene therapy / Harvey R. Herschman -- Cancer-related gene therapy clinical trials / Robert J. Korst and Ronald G. Crystal -- Regulatory aspects in the development of gene therapies / Rosemarie Aurigemma ... [et al.].
  • Cancer genetics 2010, Springer
  • Cancer genomics and proteomics 2007, Springer Protocols
    Reciprocal subtraction differential RNA display (RSDD) : an efficient technology for cloning differentially expressed genes / Devanand Sarkar, Dong-chul Kang, and Paul B. Fisher -- Cloning differentially expressed genes using rapid subtraction hybridization (RaSH) / Habib Boukerche ... [et al.] -- The application of differential display as a gene profiling tool / Ken Chien-Neng Chang ... [et al.] -- Serial analysis of gene expression (SAGE) / Fred van Ruissen and Frank Baas -- Gene expression profile analysis of tumors / Katia Basso and Riccardo Dalla-Favera -- cDNA microarray and bioinformatic analysis of nuclear factor [kappa]B related genes in squamous cell carcinoma / Zhong Chen ... [et al.] -- Gene profiling uncovers retinoid target genes / Yan Ma ... [et al.] -- Complete open reading frame (C-ORF) technique : rapid and efficient method for obtaining complete protein coding sequences / Dong-chul Kang and Paul B. Fisher -- Chromatin immunoprecipitation assays : molecular analysis of chromatin modification and gene regulation / Piyali Dasgupta and Srikumar P. Chellappan -- Manipulating genes and gene copy number by bacterial artificial chromosome transfection / Stephanie F. Phelps, Sharon Illenye, and Nicholas H. Heintz -- Molecular cytogenetic applications in analysis of the cancer genome / Pulivarthi H. Rao, Subhadra V. Nandula, and Vundavalli V. Murty -- Monitoring methylation and gene expression in cancer / Hetty Carraway and James Herman -- The use of phage display peptide libraries for basic and translational research / Renee Brissette and Neil I. Goldstein -- Yeast and mammalian two-hybrid systems for studying protein-protein interactions / Shu-ichi Matsuzawa and John C. Reed -- Ribonomic and short hairpin RNA gene silencing methods to explore functional gene programs associated with tumor growth arrest / Timothy E. Baroni ... [et al.] -- Surface-epitope masking (SEM) : an immunological subtraction approach for developing monoclonal antibodies targeting surface-expressed molecules / Neil I. Goldstein and Paul B. Fisher -- Approaches for monitoring signal transduction changes in normal and cancer cells / Paul Dent ... [et al.] -- PKR in innate immunity, cancer, and viral oncolysis / Siddharth Balachandran and Glen N. Barber -- Analysis of transformation and tumorigenicity using mouse embryonic fibroblast cells / Hong Sun and Reshma Taneja -- Analysis of growth properties and cell cycle regulation using mouse embryonic fibroblast cells / Hong Sun, Neriman Tuba Gulbagci, and Reshma Taneja -- Reverse phase protein microarrays for monitoring biological responses / Virginia Espina ... [et al.] -- Protein crystallization / Champion Deivanayagam, William J. Cook, and Mark R. Walter.
  • This is the second edition of a practice-oriented, well-illustrated manual on the microscopic grading of tumors. After an introduction on the history and basic tenets of tumor grading, subsequent chapters focus on specific organ systems. In each case, the most widely used system for grading common tumors is presented and discussed. Throughout, careful attention is paid to the principles of microscopic tumor grading, ancillary methods to improve grading, and the latest techniques used in evaluating tumors and formulating prognosis.
  • Immune infiltration in human cancer : prognostic significance and disease control / Wolf H. Fridman ... [et al.] -- Subversion and coercion : the art of redirecting tumor immune surveillance / John B. Mumm and Martin Oft -- STAT3 : a target to enhance antitumor immune response / Heehyoung Lee ... [et al.] -- Biology and clinical observations of regulatory T cells in cancer immunology / Michele W. Teng ... [et al.] -- Concepts and ways to amplify the antitumor immune response / Bent Rubin and Jean Edouard Gairin -- Angiogenesis and the tumor vasculature as antitumor immune modulators : the role of vascular endothelial growth factor and endothelin / Lana E. Kandalaft ... [et al.] -- Adoptive cellular therapy / Stephen A. Grupp and Carl H. June -- Dendritic cell subsets as vectors and targets for improved cancer therapy / Karolina Palucka ... [et al.] -- Identification of human idiotype-specific T cells in lymphoma and myeloma / Jinsheng Weng ... [et al.] -- Modulation of CTLA-4 and GITR for Cancer Immunotherapy / Francesca Avogadri ... [et al.] -- Immunobiology of cancer therapies targeting CD137 and B7-H1/PD-1 cosignal pathways / Shengdian Wang and Lieping Chen -- LAG-3 in cancer immunotherapy / Monica V. Goldberg and Charles G. Drake -- Immunologically active biomaterials for cancer therapy / Omar A. Ali and David J. Mooney -- Erratum : Identification of human idiotype-specific T cells in lymphoma and myeloma / Jinsheng Weng ... [et al.].
  • Introduction / W. Archie Bleyer ... [et al.] -- History of adolescent oncology / Cameron K. Tebbi -- Epidemiology and etiology of cancer in adolescents and young adults / Jillian M. Birch and W. Archie Bleyer -- Access to care before and during therapy / Karen H. Albritton and Tim Eden -- Older adolescents and young adults with cancer, and clinical trials: lack of participation and progress in North America / W. Archie Bleyer, Troy Budd, and Michael Montello -- Acute lymphoblastic leukemia / James Nachman, Giuseppe Masera, and W. Archie Bleyer -- Acute myelogenous leukemia / Ursula Creutzig and William G. Woods -- Hodgkin lymphoma / Tanya M. Trippett ... [et al.] -- Non-hodgkin lymphoma / Catherine Patte, W. Archie Bleyer, and Mitchell S. Cairo -- Central nervous system tumors in adolescents and young adults / David A. Walker ... [et al.] -- Soft-tissue sarcomas / Karen H. Albritton, Andrea Ferrari, and Michela Casanova -- Bone sarcomas / Michael S. Isakoff ... [et al.] -- Malignancies of the ovary / Jubilee Brown, Thomas Olson, and Susan Sencer -- Testicuar tumors / John W. Cullen and Robert Fallon -- Non-germ-cell genitourinary tract tumors / Michael Leahy and W. Archie Bleyer -- Thyroid cancer / Steven G. Waguespack and Samuel A. Wells --Malignant melanoma / Cynthia E. Herzog, W. Archie Bleyer, and Alberto S. Pappo -- Breast cancer / Marianne Phillips, Banu Arun, and W. Archie Bleyer -- Liver tumors / Marcio H. Malogolowkin, Arthur Zimmermann, and Jack Plaschkes -- Colorectal cancer / Wayne L. Furman, D. Ashley Hill, and Michael LaQuaglia -- Models of care and specialized units / Ian Lewis and Sue Morgan -- Drug compliance by adolescent and young adult cancer patients: challenges for the physician / Benjamin Gesundheit ... [et al.] -- Psychological support for adolescents and young adults / Christine Eiser and Aura Kuperberg -- Psychosocial support / Brad J. Zebrack, Mark A. Chesler, and Anthony Penn -- Health-related quality of life / Ernest R. Katz ... [et al.] -- Rehabilitation and exercise / Marilyn J. Wright -- Adolescent and young adult cancer survivors: late effects of treatment / Smita Bhatia ... [et al.] -- Ethical issues for the adolescent and young adult cancer patient: assent and end-of-life care / Susan Shurin and Eric Kodish -- Access to care after therapy / Karen E. Kinahan ... [et al.] -- Future health of survivors of adolescent and young adult cancer / Melissa M. Hudson and Kevin C. Oeffinger -- Information and resources for young adults and adolescents with cancer / David R. Freyer and Leonard J. Mattano -- Making ends meet: financial issues from the perspectives of patients and their healthcare team / David R. Freyer and Ronald D. Barr -- Challenges and opportunities - the way ahead / W. Archie Bleyer ... [et al.].
  • Cancer management in man 2011, Springer
    This book represents a comprehensive description and evaluation of the most up-to-date approaches to cancer management. Each chapter, prepared by leading basic researchers and clinicians, provides an in depth description of a specific method for cancer management. The chemotherapy section of the book is updated to include the newest drugs as well as those currently in development. Organized by drug class, this section provides the latest information on most drugs, including their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance.
  • Print Material
    Cancer biology -- Cancer immunology -- Cancer etiology -- Cancer epidemiology, prevention, and screening -- Clinical trials and outcomes assessment -- Cancer pathology -- Imaging -- Surgical oncology -- Radiation oncology -- Medical oncology -- Chemotherapy -- Chemotherapeutic agents -- Biotherapeutics -- Endocrine therapy -- Gene therapy -- Bone marrow transplantation -- Psycho-oncology -- Oncology nursing -- Cancer rehabilitation medicine -- Multidisciplinary management -- Pain and palliation -- Societal oncology -- Central nervous system -- The Eye -- Endocrine glands -- Head and neck -- The Thorax -- Gastrointestinal tract -- Genitourinary tract -- Female reproductive organs -- The Breast -- The Skin -- Bone and soft tissue -- Hematopoietic system -- Neoplasms in AIDS --- Unknown primary site -- Pediatric oncology -- Complications of cancer and their treatment -- Infection in the cancer patient -- Oncologic emergencies -- Oncology and informatics.
  • Cancer nanotechnology 2013, CRCnetBASE
    Basic principles of radiation therapy of cancers / Laurence Court and Radhe Mohan -- Biological principles of radiosensitization / Vikas Bhardwaj ... [et al.] -- Principles and applications of hyperthermia combined with radiation / Mark Hurwitz -- Synthesis and surface modification of nanomaterials for tumor targeting / Glenn Goodrich -- Safety concerns for nanomaterials in nanomedicinal applications / Qingxin Mu ... [et al.] -- Imaging with nanoparticles / Amit Joshi -- Optical microscopy of plasmonic nanoparticles / Varun P. Pattani and James Tunnell -- X-ray fluorescence computed tomography imaging of nanoparticles / Bernard L. Jones and Sang Hyun Cho -- Gold nanoparticle-mediated radiosensitization / Devika B. Chithrani -- Quantification of gold nanoparticle-mediated radiation dose enhancement / Sang Hyun Cho and Bernard L. Jones -- Semiconductor nanomaterials for radiotherapy / Ke Sheng -- Radioactive gold nanoparticle for tumor therapy / Raghuraman Kannan, Kattesh V. Katti, and Cathy Cutler -- Nanoparticles for the selective radioprotection of normal tissues / Jacob M. Berlin and Kathy A. Mason -- Gold nanoparticle-mediated hyperthermia in cancer therapy / Dev K. Chatterjee and Sunil Krishnan -- Magnetic resonance thermometry imaging for gold nanoparticle-mediated thermal therapy / R. Jason Stafford and John D. Hazle -- Modeling of plasmonic heat generation from gold nanoparticles / Francisco Reynoso and Sang Hyun Cho -- Carbon nanotubes for thermal therapy / Ravi N. Singh ... [et al.] -- Regulatory issues for clinical translations / J. Donald Payne -- Clinical translations of nanotechnology : present and future outlook / Dev K. Chatterjee, Sang Hyun Cho, and Sunil Krishnan.
  • Overview -- Diagnostic studies -- Neurologic symptoms -- Direct complications of cancer -- Indirect complications of cancer -- Complications of cancer therapy -- Neurologic complications of specific malignancies.
  • Cancer of the testis 2010, Springer
    The book covers the complete field of testis cancer including the germ cell tumors and the stromal tumors, from epidemiology to new chemotherapeutic agents and schedules, throughout genetic features, risk factors, risk adapted treatments, role of different types of surgery and special clinical situations. Special attention is focused on fertility issues, late effects of the primary therapy and the economical aspects of the different treatment policies. As a result of the third Consensus Conference, a consensual follow-up can be devised and a chapter dedicated to this controversial and not yet defined matter.
  • Cancer pain 2013, Springer
    Cancer remains a major challenge for medicine and it continues to claim lives and cause great suffering. Pain is a symptom experienced by most cancer patients regardless of disease stage, and less than 50% of cancer pain patients achieve effective pain and symptom control though available therapies. If these therapies are utilized correctly, many more patients can achieve effective control. While opioids are still seen as the mainstay of cancer pain treatment, it is necessary to examine whether this treatment strategy still holds true in the 21st century. Cancer Pain provides a comprehensive, up-to-date, practical guide to the management of pain in cancer patients. The book provides a clear, concise explanation of cancer pain syndromes, a modern understanding of the pathophysiological mechanism and an overview of recent developments in creating pre-clinical cancer pain models. It offers the reader the wide and improved options for management of cancer pain in clinical practice, including the use of opioid and non-opioid drugs, and defines the role of non-pharmacological methods for pain control. Cancer Pain also provides an overview of the latest developments in the management of cancer, which have major implications for the current and future thinking in cancer pain treatment strategy. This text is an invaluable resource for doctors, trainees and clinical nurse specialists in palliative medicine and oncology, and would be of interest to anyone who wishes to gain a better understanding of the complex nature of cancer pain and the tools available to alleviate it.
  • Cancer prevention 2007, Springer
  • Cancer prevention II 2009, Springer
  • Cancer proteomics 2008, Springer
    Proteomics technologies -- Cell signaling proteomics -- Tumor proteomics -- Bioinformatics and regulatory aspects of proteomics.
  • Cancer stem cells 2007, Springer
  • Cancer stem cells : historical perspectives and lessons from leukemia / Christopher R. Cogle -- Cancer stem cells in breast cancer / Jenny E. Chu and Alison L. Allan -- Cancer stem cells in brain cancer / Xin Wang, Chitra Venugopal, and Sheila K. Singh -- Cancer stem cells in colorectal cancer / Mauro Biffoni, Eros Fabrizi, and Lucia Ricci-Vitiani -- Cancer stem cells in pancreatic cancer / Jorge Dorado, Alicia G. Serrano, and Christopher Heeschen -- Cancer stem cells in prostate cancer / Paula Kroon ... [et al.] -- Cancer stem cells in melanoma / Ping Jin ... [et al.] -- Cancer stem cells in lung cancer / Jun Shen and Feng Jiang -- Cancer stem cells in ovarian cancer / Fang Fang ... [et al.] -- Cancer stem cells in hepatocellular cancer / Russell C. Langan and Itzhak Avital -- Cancer stem cells in head and neck cancer / Mark E.P. Prince and Samantha J. Davis -- Relationship between regulatory pathways in pluripotent stem cells and human tumors / Olga Gaidarenko and Yang Xu -- Influence of the embryonic microenvironment on tumor progression / Daniela Quail ... [et al.] -- The epithelial-to-mesenchymal transition and cancer stem cells / Jonas Fuxe -- Application of stem cell assays for the characterization of cancer stem cells / Pamela M. Willan and Gillian Farnie -- Zebrafish as a model to study stem cells in development, disease, and cancer / Viviana Anelli, Cristina Santoriello, and Marina C. Mione -- Imaging cancer stem cells / Paula Foster -- Mouse models for studying normal and cancer stem cells / David A. Hess -- Cancer stem cells and disease prognosis / Zeshaan A. Rasheed, Jeanne Kowalski, and William H. Matsui -- Mechanisms of radioresistance in cancer stem cells / Cleo Y-F Lee and Maximilian Diehn -- The role of ABC transporters in cancer stem cell drug resistance / Vera S. Donnenberg, Ludovic Zimmerlin, and Albert D. Donnenberg -- Resistance to endocrine therapy in breast cancer : are breast cancer stem cells implicated? / Ciara S. O'Brien ... [et al.] -- Future directions : cancer stem cells as therapeutic targets / Alysha K. Croker and Alison L. Allan -- Final thoughts : complexity and controversy surrounding the "cancer stem cell" paradigm / Craig Gedye, Richard P. Hill, and Laurie Ailles.
  • Cancer survivorship 2007, Springer
    Cancer survivors: a physician's perspective / Patricia A. Ganz -- Cancer survivorship: a nursing perspective / Susan Leigh -- Oncology social work for survivorship / Patricia Fobair -- Survivorship research: past, present, and future / Julia H. Rowland -- Surveillance after primary therapy / Craig C. Earle -- Late effects of cancer treatments / Noreen M. Aziz -- Medical and psychosocial issues in childhood cancer survivors / Smita Bhatia ... [et al.] -- Medical and psychosocial issues in Hodgkin's disease survivors / Jon Håvard Loge and Stein Kaasa -- Medical and psychosocial issues in testicular cancer survivors / S.D. Fosså, L.B. Travis, and A.A. Dahl -- Medical and psychosocial issues in gynecologic cancer survivors / Karen Basen-Engquist and Diane C. Bodurka -- Medical, psychosocial, and health-related quality of life issues in breast cancer survivors / Julie Lemieux, Louise J. Bordeleau, and Pamela J. Goodwin -- Medical and psychosocial issues in prostate cancer survivors / Tracey L. Krupski and Mark S. Litwin -- Physical and psychosocial issues in lung cancer survivors / Linda Sarna, Frederic W. Grannis, and Anne Coscarelli -- Cancer survivorship issues in colorectal cancer / Clifford Y. Ko and Patricia A. Ganz -- Medical and psychosocial issues in transplant survivors / Karen L. Syrjala ... [et al.] -- Cancer survivorship issues in older adults / Karim S. Malek and Rebecca A. Silliman -- Second malignancies after radiation treatment and chemotherapy for primary cancers / Lydia B. Zablotska, Matthew J. Matasar, and Alfred I. Neugut -- Psychosocial rehabilitation in cancer care / Richard P. McQuellon and Suzanne C. Danhauer -- Reproductive complications and sexual dysfunction in cancer survivors / Leslie R. Schover -- The employment and insurance concerns of cancer survivors / Barbara Hoffman -- Cancer advocacy / Ellen L. Stovall -- The survivorship care plan: what, why, how, and for whom / Craig C. Earle ... [et al.]
  • Cancer susceptibility 2010, Springer Protocols
  • Cancer systems biology 2010, CRCnetBASE
    A roadmap of cancer systems biology / Edwin Wang -- Network biology : the framework of systems biology / Jing-Dong Han -- Reconstructing gene networks using gene expression profiles / Mario Lauria and Diego di Bernardo -- Understanding cancer progression in protein interaction networks / Jinsheng Sun, Jie Li, and Edwin Wang -- From tumor genome sequencing to cancer signaling maps / Cong Fu and Edwin Wang -- Ubiquitin-mediated regulation of human signaling networks in normal and cancer cells / Cong Fu, Jie Li, and Edwin Wang -- MicroRNA regulation of networks of normal and cancer cells / Pradeep Kumar Shreenivasaiah, Do Han Kim, and Edwin Wang -- Network model of survival signaling in T-cell large granular lymphocyte leukemia / Ranran Zhang, Thomas P. Loughran Jr., and Réka Albert -- Cancer metabolic networks : metabolic pathways modelling and metabolomics in cancer research / Miroslava Cuperlovic-Culf -- Warburg revisited : modeling energy metabolism for cancer systems biology / Mathieu Cloutier --Cancer gene prediction using a network approach / Xuebing Wu and Shao Li -- Cancer genomics to cancer biology / Maria Luz Jaramillo and Chabane Tibiche -- Epithelial-to-mesenchymal transition (EMT) : the good, the bad, and the ugly / Anne EG Lenferink -- Tumors and their microenvironments / Nicholas R. Bertos and Morag Park -- Tumor angiogenesis : cell-microenvironment interactions / Ally Pen, Danica B. Stanimirovic, and Maria J. Moreno -- Modeling tools for cancer systems biology / Wayne Materi and David S. Wishart -- Advanced visualization, analysis, and inference of biological networks using visANT / Zhenjun Hu -- Gene set and pathway-based analysis for cancer omics / Dougu Nam and Seon-Young Kim -- SH2 domain signaling network and cancer / Shawn S.-C. Li and Thamara K.J. Dayarathna -- Data sources and computational tools for cancer systems biology / Yun Ma, Pradeep Kumar Shreenivasaiah, and Edwin Wang.
  • pt. 1. Introduction and background -- pt. 2. Laboratory, clinical, data and educational resources -- pt. 3. Bioinformatics and systems biology analysis -- pt. 4. Diagnosis, clinical and treatment applications -- pt. 5. Perspectives and conclusions.
  • The Cancer Genome -- Mechanisms of Genomic Instability -- Epigenetics of Cancer -- Telomeres, Telomerase, and Cancer -- Cell Signaling Growth Factors and Their Receptors -- Cell Cycle -- Mechanisms of Cell Death -- Cancer Metabolism -- Angiogenesis -- Invasion and Metastasis -- Cancer Stem Cells -- Biology of Personalized Cancer Medicine -- Tobacco -- Cancer Susceptibility Syndromes -- DNA Viruses -- RNA Viruses -- Inflammation -- Chemical Factors -- Physical Factors -- Dietary Factors -- Obesity and Physical Activity -- Epidemiologic Methods -- Global Cancer Incidence and Mortality -- Trends in Cancer Mortality -- Surgical Oncology: General Issues -- Surgical Oncology: Laparoscopic Surgery -- Radiation Oncology -- Medical Oncology -- Assessment of Clinical Response -- Cancer Immunotherapy -- Health Services Research and Economics of Cancer Care -- Pharmacokinetics and Pharmacodynamics -- Pharmacogenomics -- Alkylating Agents -- Platinum Analogs -- Antimetabolites -- Topoisomerase-Interacting Agents -- Antimicrotubule Agents -- Targeted Therapy with Small Molecule Kinase Inhibitors -- Histone Deacetylase Inhibitors and Demethylating Agents -- Proteasome Inhibitors -- Poly(ADP-Ribose) Polymerase Inhibitors -- Miscellaneous Chemotherapeutic Agents -- Interferons -- Interleukin Therapy -- Antisense Agents -- Antiangiogenesis Agents -- Monoclonal Antibodies -- Endocrine Manipulation -- Preventive Cancer Vaccines -- Tobacco Dependence and Its Treatment -- Role of Surgery in Cancer Prevention -- Principles of Cancer Risk Reduction Intervention -- Retinoids, Carotenoids, and Other Micronutrients in Cancer Prevention -- Drugs and Nutritional Extracts for Cancer Risk Reduction (Chemoprevention) -- Principles of Cancer Screening -- Early Detection Using Proteomics -- Screening for Gastrointestinal Cancers -- Screening for Gynecologic Cancers -- Screening for Breast Cancer -- Screening for Prostate Cancer -- Screening for Lung Cancer -- Genetic Counseling -- Vascular Access and Specialized Techniques -- Interventional Radiology -- Functional Imaging -- Molecular Imaging --Photodynamic Therapy -- Biomarkers -- Design and Analysis of Clinical Trials -- Molecular Biology of Head and Cancers -- Treatment of Head and Neck Cancer -- Rehabilitation after Treatment of Head and Neck Cancer -- Molecular Biology of Lung Cancer -- Non-Small Cell Lung Cancer -- Small Cell and Neuroendocrine Tumors of the Lung -- Neoplasms of the Mediastinum -- Molecular Biology of the Esophagus and Stomach -- Cancer of the Esophagus -- Cancer of the Stomach -- Molecular Biology of Pancreas Cancer -- Cancer of the Pancreas -- Molecular Biology of Liver Cancer -- Cancer of the Liver -- Cancer of the Biliary Tree -- Cancer of the Small Intestine -- Gastrointestinal Stromal Tumor -- Molecular Biology of Colorectal Cancer -- Cancer of the Colon -- Cancer of the Rectum -- Cancer of the Anal Region -- Molecular Biology of Kidney Cancer -- Cancer of the Kidney -- Molecular Biology of Bladder Cancer -- Cancer of the Bladder, Ureter, and Renal Pelvis -- Molecular Biology of Prostate Cancer -- Cancer of the Prostate -- Cancer of the Urethra and Penis -- Cancer of the Testis -- Molecular Biology of Gynecologic -- Cancer of the Cervix, Vagina, and Vulva -- Cancers of the Uterine Body -- Gestational Trophoblastic Neoplasms -- Ovarian Cancer, Fallopian Tube Carcinoma, and Peritoneal Carcinoma -- Molecular Biology of Breast Cancer -- Malignant Tumors of the Breast -- Molecular Biology of Endocrine Tumors -- Thyroid Tumors -- Parathyroid Tumors -- Adrenal Tumors -- Pancreatic Neuroendocrine Tumors -- Neuroendocrine (Carcinoid) Tumors and the Carcinoid Syndrome -- Multiple Endocrine Neoplasias -- Molecular Biology of Soft Tissue Sarcoma -- Soft Tissue Sarcoma -- Sarcomas of Bone -- Cancer of the Skin -- Molecular Biology of Cutaneous Melanoma -- Cutaneous Melanoma -- Molecular Biology of Central Nervous System Tumors -- Neoplasms of the Central Nervous System -- Molecular Biology of Childhood Cancers -- Solid Tumors of Childhood -- Leukemias and Lymphomas of Childhood -- Molecular Biology of Lymphomas -- Hodgkin Lymphoma -- Non-Hodgkin Lymphomas -- Cutaneous Lymphomas --Primary Central Nervous System Lymphoma -- Molecular Biology of Acute Leukemias -- Management of Acute Leukemias -- Molecular Biology of Chronic Leukemias -- Chronic Myelogenous Leukemia -- Chronic Lymphocytic Leukemias -- Myelodysplastic Syndromes -- Plasma Cell Neoplasms -- Cancer of Unknown Primary Site -- Benign and Malignant Mesothelioma -- Peritoneal Surface Malignancy -- Intraocular Melanoma -- AIDS-Related Malignancies -- Transplantation-Related Malignancies -- Superior Vena Cava Syndrome -- Increased Intracranial Pressure -- Spinal Cord Compression -- Metabolic Emergencies -- Metastatic Cancer to the Brain -- Metastatic Cancer to the Lung -- Metastatic Cancer to the Liver -- Metastatic Cancer to the Bone -- Malignant Effusions of the Pleura and the Pericardium -- Malignant Ascites -- Paraneoplastic Syndromes -- Autologous Stem Cell Transplantation -- Allogeneic Stem Cell Transplantation -- Infections in the Cancer Patient -- Leukopenia and Thrombocytopenia -- Cancer-Associated Thrombosis -- Nausea and Vomiting -- Diarrhea and Constipation -- Oral Complications -- Pulmonary Toxicity -- Cardiac Toxicity -- Hair Loss -- Gonadal Dysfunction -- Fatigue -- Second Primary Cancers -- Neurocognitive Effects -- Cancer Survivorship -- Management of Cancer Pain -- Nutritional Support -- Sexual Problems -- Psychological Issues in Cancer -- Communicating News to the Cancer Patient -- Specialized Care of the Terminally Ill -- Community Resources -- Rehabilitation of the Cancer Patient -- Regulatory Issues -- Health Disparities in Cancer -- Cancer Information on the Internet -- Complementary, Alternative, and Integrative Therapies in Cancer Care.
  • Introduction for scientists -- Introduction for laypersons -- What cancers are -- Environmental and other causes of cancer -- Resources used to detect local increases in risk -- Methods used to detect local increases in risk -- Errors due to chance -- Comparison between "apples" and "oranges" -- Failure to detect local increases in risk -- Investigating a lead -- Guide to the figures -- Interpretation -- Scientific and technical notes -- Oropharyngeal carcinoma -- Salivary gland malignancies -- Squamous carcinoma of the esophagus/gastric cardia -- Adenocarcinoma of the esophagus/gastric cardia -- Adenocarcinoma of the (lower) stomach -- Carcinoma of the small intestine -- Colon carcinoma, total (both upper and sigmoid) -- Carcinoma of the upper colon -- Carcinoma of the sigmoid colon -- Carcinoma of the rectum -- Hepatocellular carcinoma -- Cholangiocarcinoma -- Gallbladder carcinoma -- Biliary tract carcinoma -- Pancreas carcinoma -- Carcinoma of the nose/sinuses -- Carcinoma of the larynx -- Lung and bronchus carcinoma, total (all types) -- Squamous cell carcinoma of the lung and bronchus -- Large cell carcinoma of the lung and bronchus -- Small cell carcinoma of the lung and bronchus -- Adenocarcinoma of the lung and bronchus -- Bronchioloalveolar carcinoma of the lung and bronchus -- Undifferentiated carcinoma of the lung and bronchus -- Carcinoma of the lung and bronchus, not otherwise classified -- Mesothelioma -- Soft tissue sarcoma -- Angiosarcoma -- Kaposi sarcoma -- Osteosarcoma -- Ewing's sarcoma -- Malignant chordoma -- Malignant melanoma -- Breast carcinoma -- Squamous cervix carcinoma (invasive) -- Endometrial (uterine corpus) carcinoma -- Epithelial carcinoma of the ovary -- Germ cell malignancies --Prostate carcinoma -- Anogenital adenocarcinoma -- Anogenital squamous carcinoma -- Mixed cell genital tumors -- Transitional cell (non-squamous) bladder carcinoma -- Squamous bladder carcinoma -- Renal cell carcinoma -- Wilms tumor (nephroblastoma) -- Retinoblastoma -- Brain malignancies (gliomas) -- Spinal cord malignancies -- Neurolemoma (nerve sheath malignancy) -- Neuroblastoma -- Malignant meningioma -- Papillary carcinoma of the thyroid -- Follicular carcinoma of the thyroid -- Other carcinoma of the thyroid -- Pituitary carcinoma -- Multiple endocrine neoplasia -- Carcinoma of the thymus -- Mixed cellularity Hodgkin lymphoma -- Nodular sclerosis Hodgkin lymphoma -- Other Hodgkin lymphoma -- All non-Hodgkin lymphomas (all non-Hodgkin lymphoma types) -- Follicular non-Hodgkin lymphoma -- Diffuse large B-cell non-Hodgkin lymphoma -- Diffuse small lymphocytic or plasmacytic B-cell non-Hodgkin lymphoma -- Diffuse mixed B-cell non-Hodgkin lymphoma -- High-grade non-Hodgkin lymphoma -- T-cell non-Hodgkin lymphoma -- Maltoma non-Hodgkin lymphoma -- Other non-Hodgkin lymphoma -- Central nervous system non-Hodgkin lymphomas (all non-Hodgkin lymphoma types) -- Stomach non-Hodgkin lymphomas (all non-Hodgkin lymphoma types) -- Other gastrointestinal non-Hodgkin lymphomas (all non-Hodgkin lymphoma types) -- Lymph node/other organ non-Hodgkin lymphomas (all non-Hodgkin lymphoma types) -- Multiple myeloma -- Acute lymphoblastic leukemia -- Chronic lymphocytic leukemia -- Hairy cell leukemia -- Acute non-lymphocytic leukemia -- Chronic myelocytic leukemia -- Other leukemias -- All malignancies of infants/toddlers -- All malignancies of older children -- All malignancies of young adults -- All malignancies of older adults -- All malignancies -- Overall summary.
  • Carbon Black -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale -- -- Titaniium Dioxide -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale -- -- Talc Not Containing Asbestiform Fibres -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale.
  • Cardiac tumor pathology 2013, Springer
  • Caveolins and caveolae 2012, Springer
    Lipid rafts, caveolae, and GPI linked proteins / Valerie L. Reeves, Candice M. Thomas, and Eric J. Smart -- Caveolae and the regulation of endocytosis / Anna L. Kiss -- Caveolin : role in cell signaling / Cecile Boscher and Ivan Robert Nabi -- Regulation of ENOS in caveolae / Chieko Mineo and Philip W. Shaul -- Recent developments in the interactions between caveolin and pathogens / Fabiana S. Machado ... [et al.] -- Caveolin and breast cancer : a new clinical perspective / Isabelle Mercier and Michael P. Lisanti -- Caveolin and prostate cancer progression / Michael R. Freeman, Wei Yang, and Dolores Di Vizio -- Caveolins and caveolae, roles in insulin signalling, and diabetes / Peter Strolfors -- Atherosclerosis, caveolae, and caveolin / Stephanos Pavlides ... [et al.] -- Caveolins and heart diseases / Mathivadhani Panneerselvam, Hemal H. Patel, and David M. Roth -- Caveolins and lung function / Nikolaos A. Maniatis ... [et al.].
  • 1. Local and Distant Effects of Caveolin-1 on Prostate Cancer Progression / T.C. Thompson, S.A. Tahir, L. Li, M. Watanabe, K. Naruishi, G. Yang, Ken-ichi Tabata, S. Kurosaka, K. Edamura, R. Tanimoto, P. Corn, D. Kadmon, C.J. Logothetis, P. Troncoso, C. Ren, A. Goltsov, and S. Park -- 2. Caveolin-1 in Colon Cancer: The Flexible Connection to Wnt Signaling / Andrew F.G. Quest, Vicente A. Torres, Diego A. Rodriguez, Jorge Gutierrez-Pajares, and Julio C. Tapia -- 3. Caveolin-1 and Pancreatic Ductal Adenocarcinoma / David W. Rittenhouse, Oeendree Mukherjee, Nathan G. Richards, Charles J. Yeo, Agnieszka K. Witkiewicz, and Jonathan R. Brody -- 4. Caveolin-1 in Brain Tumors / Rebecca Senetta and Paola Cassoni -- 5. The Role of Caveolin-1 in Skin Cancer -- / Alessandra Carè, Isabella Parolini, Federica Felicetti, and Massimo Sargiacomo -- 6. Caveolins in Tumor Angiogenesis / Grzegorz Sowa -- 7. Caveolin-1 and Breast Cancer / Gloria Bonuccelli and Michael P. Lisanti -- 8. Caveolin-1 and Cancer-Associated Stromal Fibroblasts / Isabelle Mercier and Michael P. Lisanti.
  • 1. GRB2 Signaling as a Molecular Target for Cancer / Alessio Giubellino -- 2. Human Arylamine N-acetyltransferase 1: From Drug Metabolism to Drug Target / Fernando Rodrigues-Lima, Julien Dairou, Florent Busi, and Jean-Marie Dupret -- 3. Targeting Argininosuccinate Synthetase in Cancer Therapy / Niramol Savaraj, Min You, Chunjing Wu, Macus Tien Kuo, Vy Dinh, Medhi Wangpaichitr, and Lynn Feun -- 4. Parathyroid Hormone-Related Peptide Signaling in Cancer / Franco Oreste Ranelletti and Giovanni Monego -- 5. Signalling Molecules as Selective Targets for Therapeutic Strategies in Multiple Myeloma / Francesco Piazza and Gianpietro Semenzato -- 6. Role of Bile Acids in Carcinogenesis of Gastrointestinal Tract / Hiroshi Yasuda and Fumio Itoh -- 7. AIB1: A Transcriptional Coactivator Which Integrates Signaling Cross Talk in Cancer Cells / Macarena Ferrero and Jaime Font de Mora -- 8. Rational Design of DNA Anticancer Agent That Targets Signal Transducer and Activator of Transcription 3 (Stat3) for Cancer Therapy / Naijie Jing -- 9. Estrogen Receptor Signaling in Lung Cancer / P.A. Hershberger and J.M. Siegfried -- 10. Microparticle Dissemination of Biological Activities: Implications for Cancer Biology / Pauline P. Goh -- 11. Protein Kinase D Signaling in Cancer / Peter Storz -- 12. Cell Signaling and Cancer: Integrated, Fundamental Approach Involving Electron Transfer, Reactive Oxygen Species, and Antioxidants / Peter Kovacic and Ratnasamy Somanathan -- 13. Targeting Signal Transducer and Activator of Transcription (STAT) for Anticancer Therapy / Fabio P.S. Santos, Inbal Hazan-Halevy, and Zeev Estrov.
  • Checkpoint controls and cancer v. 1-2, 2004., Springer Protocols
    v. 2, 2004 Springer Protocols
    v. 1. Reviews and model systems -- v. 2. Activation and regulation protocols.
  • Chemical carcinogenesis 2011, Springer
  • Introduction to cancer -- Antimetabolites -- DNA-interactive agents -- Antitubulin agents -- Cell signaling inhibitors -- Hormonal therapies -- Tumour targeting strategies -- Biologicals -- The future -- Personalized medicine (oncogenomics) -- Adjunct therapies.
  • Chemo fog 2010, Springer
    Short introduction and history / Robert B. Raffa -- Patient's perspective / Robert B. Raffa and Kathy Martin -- Oncology nurse's perspective / Jamie S. Myers -- Oncology pharmacist's perspective / Rachel Clark-Vetri -- The impact of chemo brain on the patient with a high grade glioma / Michele R. Lucas -- Oncology pharmacist's perspective / Rachel Clark-Vetri -- The impact of chemo brain on the patient with a high grade glioma / Michele R. Lucas -- Neurocognitive effects of childhood cancer treatment / Jennifer Costa -- The economic burden / Albert I. Wertheimer -- Designing conceptual model-based research in chemotherapy-related changes in cognitive function / Lisa M. Hess -- Neuropsychologic testing for chemotherapy-related cognitive impairment / Jamie S. Myers -- Imaging as a means of studying chemotherapy-related cognitive impairment / Robert B. Raffa -- Chemotherapy associated central nervous system damage / Jørg Dietrich -- Is systemic anti-cancer therapy neurotoxic? Does chemo brain exist? And should we rename it? / Sophie Taillibert -- Evaluation of multiple neurotoxic outcomes in cancer chemotherapy / Bernard Weiss -- Chemotherapy-related visual system toxicity / Robert B. Raffa -- The possible role of cytokines in chemotherapy-induced cognitive deficits / Jamie S. Myers -- Pharmacokinetics of anti-cancer drugs used in breast cancer chemotherapy / Swati Nagar -- Combination analysis / Ronald J. Tallarida -- Animal models / Ellen A. Walker -- Chemo brain (chemo fog) as a potential side effect of doxorubicin administration : role of cytokine-induced, oxidative/nitrosative stress in cognitive dysfunction / Christopher D. Aluise ... [et al.] -- Effects of 5-FU / Peter M. Wigmore ... [et al.] -- Future directions / Robert B. Raffa and Ronald J. Tallarida.
  • Chemosensitivity v. 1-2, 2005., Springer Protocols
    v. 2, 2005 Springer Protocols
    v. 1. In vitro assays -- v. 2 In vitro models, imaging, and molecular regulators.
  • Scientific basis of cancer chemotherapy -- Norton-simon hypothesis -- Drug resistance -- Principles of chemotherapy -- Clinical trials -- Hematopoietic growth factors -- Biologic response modifiers: principles of biotherapy -- Intraventricular and intrathecal therapy -- Intraperitoneal chemotherapy -- Continuous intravenous infusion chemotherapy -- Intraarterial chemotherapy -- Isolated regional therapy -- Hematopoietic stem cell transplantation -- Oral toxicity -- Dermatologic toxicity -- Extravasation -- Hypersensitivity reactions -- Ocular side effects of chemotherapy -- Cardiotoxicity of cancer therapy -- Pulmonary toxicity of antineoplastic therapy -- Gastrointestinal complications of chemotherapy -- Hepatotoxicity of chemotherapeutic agents -- Renal and electrolyte abnormalities due to chemotherapy -- Chemotherapy-induced peripheral neuropathy -- Vascular toxicity of antineoplastic agents -- Second malignancies after chemotherapy -- Chemotherapy in pregnancy -- Gonadal complications and teratogenicity of cancer therapy -- Central venous access for chemotherapy -- Systemic therapy for advanced melanoma -- General issues in brain tumor chemotherapy -- Chemotherapy of head and neck cancer -- Chemotherapy of lung cancer -- Breast cancer -- Gastrointestinal cancer -- Endocrine tumors -- Chemotherapy of genitourinary cancers -- Chemotherapy of gynecologic cancers -- Chemotherapy of carcinoma of unknown primary site -- Chemotherapy of bone and soft tissue sarcomas -- Chemotherapy for pediatric solid tumors -- Chemotherapy of hodgkin's lymphoma -- Non-hodgkin's lymphoma -- Acute myeloid leukemia, acute lymphoblastic leukemia, and chronic lymphocytic leukemia -- Chemotherapy of the myelodysplastic syndromes -- Management of myeloproliferative disorders and chronic myeloid leukemia -- Chemotherapy of multiple myeloma and other plasma cell disorders.
  • Introduction to Electroporation -- Electroporation and Cellular Physiology -- The Cell in the Electric Field -- Understanding Electric Fields for Clinical Use -- Generators and Applicators: Equipment for Electroporation -- Cell Electropermeabilization and Cellular Uptake of Small Molecules: The Electrochemotherapy Concept -- Vascular-Disrupting Action of Electrochemotherapy: Mode of Action and Therapeutic Implications -- Electrochemotherapy of Small Tumors; The Experience from the ESOPE (European Standard Operating Procedures for Electrochemotherapy) Group -- Electrochemotherapy for Larger Malignant Tumors -- Cell Electroporation in Bone Tissue -- Drug and Gene Electrotransfer to the Brain -- Minimally Invasive Intraluminal Tumor Ablation -- Electrotransfer of Plasmid DNA -- Gene Electrotransfer to Tumor -- Gene Electrotransfer to Lung -- Gene Electrotransfer to Muscle Tissue: Moving into Clinical Use -- Gene Electrotransfer to Skin -- Electroporation-Mediated DNA Vaccination -- Irreversible Electroporation (IRE) on Liver Tumor Ablation: A Summary of Preclinical Translational Research -- Translational Research on Irreversible Electroporation: VX2 Rabbit Head and Neck -- Clinical Research on Irreversible Electroporation of the Liver.
  • My Aunt Minnie -- Screening -- Diagnostic breast imaging -- Management.
  • Conceived as a guide for practitioners in their work in dermatology, this book is unique in its approach. From cutaneous signs to the richness of differential diagnosis, it guides practitioners through every step, from semiological analysis to diagnosis. The aim is to provide readers with the essentials of relevant dermatological reasoning. The first part of the book focuses on physical examination and on recognizing basic lesions, the practitioners building blocks. The diseases requiring understanding are then described in the form of a richly illustrated atlas, in which each diagram has been chosen as an exemplary educational tool. In the final part, differential diagnosis is proposed in the form of various tables summarizing the different cutaneous signs, providing readers with a complete toolkit to assist with diagnosis. This book will give trainee dermatologists, general physicians and internists the knowledge they need to identify basic lesions and a complete and detailed overview of the various diseases they are likely to encounter. At the same time, experienced dermatologists will find this book a valuable reference work for differential diagnosis.
  • Print Material
  • CNS cancer 2009, Springer
    Covers three areas of research in brain tumors: a) animal models for brain tumors, including spontaneous occurrence of brain tumors in mammals, transgenic models in rodents and transplant models; b) Prognostic factors and biomarkers; c) Therapeutic targets and targeting approaches to brain tumors.
  • Coagulation in cancer 2009, Springer
  • Metallic cobalt particles (with or without tungsten carbide) -- Introduction to the monographs on gallium arsenide and indium phosphide. Studies of cancer in humans -- Gallium arsenide -- Indium phosphide -- Vanadium pentoxide.
  • Colorectal cancer 2007, Springer
    Molecular biology of colon cancer / William M. Grady -- Chemoprevention of colorectal cancer / Yu-Ning Wong ...[et al.] -- Colorectal cancer screening and surveillance / Arnold J. Markowitz -- Cytotoxic chemotherapy for metastatic colorectal cancer / M. Wasif Saif, Richard Kim, and Edward Chu -- Integration of antiangiogenic strategies in colorectal cancer treatment / John M. Strother and Charles D. Blanke -- The role of EGFR inhibition in colorectal cancer / Nabeel Shalan and Paulo M. Hoff -- Second-line strategies in the treatment of patients with metastatic colorectal cancer / Anthony B. El-Khoueiry and Heinz-Josef Lenz -- Adjuvant chemotherapy for colon cancer / Bert H. O'Neil ... [et al.] -- Management of locally advanced rectal cancer / Yu Jo Chua and David Cunningham -- Rationale for adjuvant and neoadjuvant chemotherapy in the resection of liver metastases / Axel Grothey and Steven A. Alberts -- Percutaneous radiofrequency ablation in the management of patients with colorectal cancer / Karen Brown -- Colorectal cancer imaging / Sean D. Curran and Laurence H. Schwartz -- Nursing issues in colorectal cancer chemotherapy / Ellen Hollywood and Deborah Semple -- Pain management in the colorectal cancer patient / Vivek Tim Malhotra -- Novel agents and new paradigms for colorectal cancer / Chris Takimoto and Russell Kruzelock.
  • Colorectal cancer 2009, Springer
  • Targeting of the EGFR as a modulator of cancer chemotherapy / Jose Baselga -- Cyclin dependent kinase inhibitors in combination chemotherapy / Manish A. Shah and Gary K. Schwartz -- Development of protein kinase C and cyclin-dependent kinase inhibitors as potentiators of cytotoxic drug action in leukemia / Steven Grant -- Carboxyamidotriazole, an inhibitor of nonvoltage operated calcium entry : single agent and combination therapy for ovarian carcinoma / Chad M. Michener and Elise C. Kohn -- Targeted alpha particle therapy : a rational approach to drug development in hematologic diseases and solid tumors / John M. Burke, David A. Scheinberg, and Joseph G. Jurcic -- Pharmacologic modulation of fluoropyrimidines : building upon the lessons of the past / Owen A. O'Connor -- Development of inhibitors of HER2 with taxanes : new directions in breast cancer therapy / Shanu Modi, Monica N. Fornier, and Andrew D. Seidman -- Targeting nf-b to increase the activity of cisplatin in solid tumors / Don S. Dizon ... [et al.] -- Combinations of chemotherapy and G3139, an antisense BCL-2 oligonucleotide / Luba Benimetskaya, Sridhar Nami, and C. A. Stein -- Use of animal models to evaluate signal transduction inhibitors as modulators of cytotoxic therapy / Beverly A. Teicher.
  • Computational biology 2009, Springer
    Identification of Relevant Genes from Microarray Experiments based on Partial Least Squares Weights: Application to Cancer Genomics -- Geometric Biclustering and Its Applications to Cancer Tissue Classification Based on DNA Microarray Gene Expression Data -- Statistical Analysis on Microarray Data: Selection of Gene Prognosis Signatures -- Agent-Based Modeling of Ductal Carcinoma In Situ: Application to Patient-Specific Breast Cancer Modeling -- Multicluster Class-Based Classification for the Diagnosis of Suspicious Areas in Digital Mammograms -- Analysis of Cancer Data Using Evolutionary Computation -- Analysis of Population-Based Genetic Association Studies Applied to Cancer Susceptibility and Prognosis -- Selected Applications of Graph-Based Tracking Methods for Cancer Research -- Recent Advances in Cell Classification for Cancer Research and Drug Discovery -- Computational Tools and Resources for Systems Biology Approaches in Cancer -- Laser Speckle Imaging for Blood Flow Analysis -- The Challenges in Blood Proteomic Biomarker Discovery.
  • Contemporary IMRT 2005, CRCnetBASE
  • Content-based image retrieval (CBIR) is the process of retrieval of images from a database that are similar to a query image, using measures derived from the images themselves, rather than relying on accompanying text or annotation. To achieve CBIR, the contents of the images need to be characterized by quantitative features; the features of the query image are compared with the features of each image in the database and images having high similarity with respect to the query image are retrieved and displayed. CBIR of medical images is a useful tool and could provide radiologists with assistance in the form of a display of relevant past cases. One of the challenging aspects of CBIR is to extract features from the images to represent their visual, diagnostic, or application-specific information content. In this book, methods are presented for preprocessing, segmentation, landmarking, feature extraction, and indexing of mammograms for CBIR. The preprocessing steps include anisotropic diffusion and the Wiener filter to remove noise and perform image enhancement. Techniques are described for segmentation of the breast and fibroglandular disk, including maximum entropy, a moment-preserving method, and Otsu's method. Image processing techniques are described for automatic detection of the nipple and the edge of the pectoral muscle via analysis in the Radon domain. By using the nipple and the pectoral muscle as landmarks, mammograms are divided into their internal, external, upper, and lower parts for further analysis. Methods are presented for feature extraction using texture analysis, shape analysis, granulometric analysis, moments, and statistical measures.
  • Prognostic factors in histopathology of lung cancer / A. Fisseler-Eckhoff -- FDG-PET/CT in lung cancer : an update / R.-P. Baum, C. Świętaszczyk, V. Prasad -- Whole-body magnetic resonance imaging for staging of lung cancer / R. Puls ... [et al.] -- Bronchoscopy/endobronchial ultrasound / F.J.F. Herth -- New developments in videomediastinoscopy : video-assisted mediastinoscopic lymphadenectomy and mediastinoscopic ultrasound / B. Witte -- Resection in stage I/II non-small cell lung cancer / F.M. Smolle-Juettner ... [et al.] -- Role of mediastinal lymph node dissection in non-small cell lung cancer / S. Bölükbas, M.H. Eberlein, J. Schirren -- Radiation therapy for early stage (I/II) non-small cell lung cancer / B. Jeremic ... [et al.] -- Stereotactic body radiation therapy for early non-small cell lung cancer / F. Zimmermann ... [et al.] -- Extended surgical resection in stage III non-small cell lung cancer / S. Hillinger, W. Weder -- Stage III : definitive chemoradiotherapy / R. Fietkau, S. Semrau -- Adjuvant therapy in early-stage non-small cell lung cancer / M. Serke -- Postoperative irradiation in non-small cell lung cancer / S. Höcht ... [et al.] -- Altered fractionation schemes in radiotherapy / M. Stuschke, C. Pöttgen -- Chemotherapy of advanced non-small cell lung cancer / R. Pirker, W. Minar -- Radiotherapy / I.A. Adamietz -- Treatment of limited disease small cell lung cancer / D. de Ruysscher -- Radiochemotherapy in extensive disease small cell lung cancer ED-SCLC / B. Jeremic ... [et al.] -- Radiotherapy for extensive stage small cell lung cancer / B.J. Slotman -- Controversies in the treatment of advanced stages of small cell lung cancer / A. Schmittel -- Complementary and alternative medicine in lung cancer patients : a neglected phenomenon? / O. Micke.
  • Prostate cancer and active surveillance / Abrahamsson, P.A. -- Radical Prostatectomy in the 21th Century: the gold standard for localized and locally advanced prostate cancer / Schostak, M.; Miller, K.; Schrader, M. -- Radiotherapy as primary treatment modality / Sia, M.; Rosewall, T.; Warde, P. -- Combined radiotherapy and hormonal therapy in the treatment of prostate cancer / Boehmer, D. -- Postoperative adjuvant radiotherapy: standard of care? / Bottke, D.; Wiegel, T. -- Adjuvant hormonal treatment: the bicalutamide early prostate cancer program / Wirth, M.P.; Hakenberg, O.W.; Froehner, M. -- Hormone therapy for prostate cancer: immediate initiation / Schostak, M.; Miller, K.; Schrader, M. -- Lymphadenectomy in prostate cancer: radioguided lymph node mapping: an adequate staging method / Winter, A.; Wawroschek, F. -- Radiotherapy in lymph-node positive prostate cancer patients: potentially curable?: single institutional experience regarding outcome and side effects / Goldner, G.; Pötter, R. -- Radiotherapy in biochemical recurrences after surgery for prostate cancer / Hocht, S. ... [et al.] -- Recurrence following radiotherapy / Desgrandchamps, F. -- Secondary hormonal manipulation / Merseburger, A.S. ... [et al.] -- Chemotherapy in hormone-refractory prostate cancer / Wolff, J.M. -- A randomized phase II trial comparing weekly taxotere + prednisone (P) versus prednisone alone in androgen-independent prostate cancer / Fossa, S.D. -- Hormone-refractory and metastatic prostate cancer: palliative radiotherapy / Moser, L.; Schubert, T.; Hinkelbein, W.
  • Cutaneous lymphomas - radiotherapeutic strategies / Wilson, L.D., Jones, G.W., Smith, B.D. -- The clinical impact of T cell receptor rearrangement analysis in cutaneous T cell lymphoma / Assaf, C. -- Classification of primary cutaneous lymphomas / Assaf, C. ... [et al.] -- Basal cell and squamous cell carcinoma - radiotherapeutic approaches / Panizzon, R.G. -- Kaposi's sarcoma - radiotherapeutic aspects / Niewald, M.; Räbe, C. -- Pathogenesis and clinical manifestation of Kaposi's sarcoma / Geilen, C.C., Husak, R., Steinhoff, M. -- Merkel cell carcinoma - clinical presentation and treatment / Moll, I. -- Merkel cell carcinoma - uncommon and aggressive cutaneous tumour / Greiner, R.H. ... [et al.] -- Potential of radiation therapy in the multimodal management of Merkel cell carcinoma / Becker, G., Bottke, D. --Skin and other reactions to radiotherapy - clinical presentation and radiobiology of skin reactions / Dörr, W. -- Management of skin and related reactions to radiotherapy / Seegenschmiedt, H. -- Malignant melanoma - markers for progression and prognosis in malignant melanoma / Geilen, C.C. ... [et al.] -- Malignant melanoma - sentinel lymph node biopsy and surgical procedures / Kaufmann, R. -- The role of radiotherapy in malignant melanoma / Marnitz, S., Hoecht, S., Hinkelbein, W. -- Malignant melanoma: classification and staging of malignant melanoma / Eigentler, T.K., Garbe, C. -- Malignant melanoma: PET/CT as a staging procedure / Müller, S.P. -- Malignant melanoma - clinical development of peptide-based melanoma vaccines / Schmittel, A. ... [et al.].
  • Development of a conditional mouse model for head and neck squamous cell carcinoma / Bindels, E.M.J., van de Brekel, M.W.M. -- Hypofolatemia as a risk factor for head and neck cancer / Almadori, G. ... [et al.] -- Reduced DNA repair capacity in laryngeal cancer subjects: a comparison of phenotypic and genotypic results / Gajacka, M. ... [et al.] -- Intratumoral genomic heterogeneity in advanced head and neck cancer detected by comparative genomic hybridization / Götte, K. ... [et al.] -- Function and importance of p63 in normal oral mucosa and squamous cell carcinoma of the head and neck / Thurfjell, N. ... [et al.] -- p53, p63 and p73 expression in squamous cell carcinomas of the head and neck and their response to cisplatin exposure / Balz, V. ... [et al.] --Expression of p16 protein is associated with human papillomavirus status in tonsillar carcinomas and has implications on survival / Wittekindt, C. ... [et al.] -- EGFR-antibody-supplemented TPF chemotherapy: preclinical investigations to a novel approach for head and neck cancer induction treatment / Knecht, R. ... [et al.] -- Nuclear factor kappa B as a common target and activator of oncogenes in head and neck squamous cell carcinoma / Chang, A.A., Van Waes, C. -- Antiangiogenic therapy of head and neck squamous cell carcinoma by vascular endothelial growth factor antisense therapy / Riedel, F. ... [et al.] -- Expression pattern of chemokine receptors 6 and 7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype / Wang, J. ... [et al.] -- p53-based immunotherapy of cancer / De Leo, A.B. --p53 as an immunotherapeutic target in head and neck cancer: approaches to reversing unresponsiveness of T lymphocytes and preventing tumor escape / Hoffmann, T.K. ... [et al.] -- Imbalance in absolute counts of T lymphocyte subsets in patients with head and neck cancer and its relation to disease / Kuss, I. ... [et al.] -- Antitumor immunization of head and neck squamous cell carcinoma patients with a virus-modified autologous tumor cell vaccine / Herold-Mende, C. ... [et al.] -- Prognostic factors: confusion caused by bad quality of design, analysis and reporting of many studies / Sauerbrei, W.
  • Cutaneous lymphomas v. 2, 2006., Springer
    v. 2 Unusual cases.
  • Cytokines and cancer 2005, Springer
  • Helicobacter pylori and cytokines in the genesis of gastric cancer / Richard M. Peek, Jr. -- HTLV-1, cytokines, and cancer / Michael Lairmore and Lee Ratner -- Herpesviruses, cytokines, and cancer / Frank J. Jenkins and Heather R. Hensler -- Tumor necrosis factor and cancer / Mark DeWitte ... [et al.] -- Transforming growth factor-[beta] and cancer / Alyssa R. Bonine-Summers, Brian K. Law, and Harold L. Moses -- Interleukin-1 family of cytokines and cancer / Michael T. Lotze--Interleukin-4/13 and cancer / Koji Kawakami and Raj K. Puri -- Interleukin-6 and Castleman's disease / Norihiro Nishimoto -- Interleukin-10 (IL-10): biology, immune, regulation, and cancer / Shin-ichiro Fujii and Michael T. Lotze -- Cytokines in multiple myeloma: therapeutic implications / Dharminder Chauhan, Teru Hideshima, and Kenneth C. Anderson -- In vivo murine cytokine models and the genesis of cancer / Todd A. Fehniger, Megan A. Cooper, Michael A. Caligiuri --Experimental models of cytokines and cancer prevention / Mark J. Smyth ... [et al.] -- Cytokines in the tumor stroma / Michael C. Ostrowski -- Cytokines and tumor angiogenesis / Sharmila Roy-Chowdhury and Charles K. Brown -- Chemokine and receptor expression in tumor progression / Paola Allavena, Federica Marchesi, and Alberto Mantovani -- The biology of cancer cachexia and the role of TNF-[alpha] / Denis C. Guttridge -- Interleukin-2 and cancer therapy / Kim Margolin and Joseph Clark -- Interleukin-12 and cancer therapy / Timothy E. Bael and Jared Gollob -- The type I interferon system with emphasis on its role in malignancies: interferons are more than "antivirals" / Stergios J. Moschos ... [et al.] -- Combination cytokine therapy / Seth M. Cohen and Howard L. Kaufman -- Novel strategies for cytokine administration via targetting / Paul M. Sondel ... [et al.] -- Cytokines and cancer vaccines / Hideho Okada and Michael T. Lotze -- Anticytokine therapy / Miguel A. Villalona-Calero -- Cytokines in the supportive care of cancer / John A. Glaspy.
  • In recent decades, cytopathology has assumed an increasing role in the primary diagnosis of mass lesions owing to its ability to provide rapid, non-invasive, and timely information. With cytopathology at the forefront of diagnosis and prognostication of neoplastic lesions, it is essential that physicians involved in the diagnosis and treatment of precancerous lesions and cancer have a clear understanding of specimen collection techniques, terminology for reporting, and outcomes in various diagnostic categories. This book provides a comprehensive overview of the role of cytology at various body sites. The diagnostic details covered are abbreviated in comparison with those in pathology texts. Instead, a more clinical approach is taken, with the focus on the advantages and limitations of techniques and the key features of entities that are important to clinicians. Pathological clinical correlation is highlighted throughout the book, ensuring that it will be highly relevant for clinicians. In particular, physicians who deal with oncology patients will find it to be a rich source of guidance on how to use and understand cytopathology in the diagnosis and exclusion of malignancy.
  • Cytopathological techniques for the diagnosis of glandular lesions of the genital tract -- Bethesda System Classification of glandular lesions on cervical cytology -- Cytopathology of the benign glandular lesions of the cervix and glandular cytopathology of the vagina -- Cytopathology of adenocarcinoma in situ of the endocervix and its differential diagnosis -- Cytopathology of the malignant invasive lesions of the endocervix -- Endometrial hyperplasias -- Endometrial adenocarcinoma : current status and future of prevention and early diagnosis -- Cytopathology of ovarian lesions : the intraoperative approach -- Glandular lesions of the vulva -- Glandular lesions of the fallopian tube -- Metastatic glandular lesions -- Ancillary techniques for the diagnosis of glandular lesions of the female genital tract
  • Part 1.Basics of the Cytoskeleton --ACTIN /Vera Dugina, Richard Arnoldi, Paul A. Janmey and Christine Chaponnier --Microtubules /Pavel Dráber and Eduarda Dráberová --The Kinesin Superfamily /Linda Wordeman --Basics of the Cytoskeleton: Myosins /Omar A. Quintero, Judy E. Moore and Christopher M. Yengo --Part 2.Actin and Disease --The Actin Cytoskeleton and Membrane Organisation in T Lymphocytes /Rhea Cornely, Thomas Grewal and Katharina Gaus --Thin Filament Diseases of Striated Muscle /Anthony J. Kee and Edna C. Hardeman --Filamins and Disease /Stephen P. Robertson and Philip B. Daniel --LIM Kinase and Cancer Metastasis /Alice Schofield and Ora Bernard --Actin Mutations and Deafness /Matías Morín, Fernando Mayo, Felipe Moreno and Miguel A. Moreno-Pelayo --Therapeutic Targeting of the Actin Cytoskeleton in Cancer /Teresa Bonello, Jason Coombes, Galina Schevzov, Peter Gunning and Justine Stehn.Part 3.Microtubules and Disease --Microtubules as a Target in Cancer Therapy /April L. Risinger and Susan L. Mooberry --Microtubules, Drug Resistance, and Tumorigenesis /Joshua A. McCarroll and Maria Kavallaris --Posttranslational Modifications of Tubulin /Suzan K. Chao, Chia-Ping H. Yang and Susan Band Horwitz --Stathmin and Cancer /Dominic Chi Hiung Ng and Frances Byrne --The Biology and Pathobiology of Tau Protein /Garth F. Hall --Tubulin-Related Malformations of Cortical Development /Xavier H. Jaglin, Jamel Chelly and Nadia Bahi-Buisson --Part 4.Intermediate Filaments and Disease --Spectrins in Human Diseases /Marie-Christine Lecomte --Laminopathies /Nadir M. Maraldi and Giovanna Lattanzi --Desmin and Heart Disease /J. Scott Pattison and Jeffrey Robbins --Neurodegenerative Diseases and Intermediate Filaments /Rodolphe Perrot and Jean-Pierre Julien.
  • The role of TNF in cancer / Harald Wajant -- Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses / Madhu Ramaswamy ... [et al.] -- FasL expression and reverse signaling / M. Lettau ... [et al.] -- Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling / Stefan Schütze and Wulf Schneider-Brachert -- Ubiquitination and TNFR1 signaling / Ken-ichi Fujita and Srinivasa M. Srinivasula -- From biochemical principles of apoptosis induction by TRAIL to application in tumour therapy / Stefanie M. Cordier, Kerstin Papenfuss, and Henning Walczak -- Therapeutic targeting of TWEAK/Fn14 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway / Jennifer S. Michaelson and Linda C. Burkly -- APRIL in B-cell malignancies and autoimmunity / Fiona C. Kimberly, Jan Paul Medema, and Michael Hahne -- Autophagy in cancer and chemotherapy / Shida Yousefi and Hans-Uwe Simon -- Glucocorticoid-mediated apoptosis resistance of solid tumors / Ingrid Herr, Markus W. Büchler, and Jürgen Mattern -- Targeting death-receptors in radiation therapy / Olivier Niemöller and Claus Belka -- Death ligands designed to kill: development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands / Jeannette Gerspach, Harald Wajant, and Klaus Pfizenmaier.
  • v. 2, 2011 Springer
  • The central role of dendritic cells in immunity / Jessica Chu and Russell D. Salter -- Dendritic cells in cancer: emergence of the discipline / Michael R. Shurin and Michael T. Lotze -- Part I. Alterations of the dendritic cell system in cancer -- Tumor-infiltrating dendritic cells: the pathologist's perspective / Dmitry W. Gutkin -- Functional defects of dendritic cells in cancer / Mikhail M. Dikov and Irina S. Chekneva -- General properties of dendritic cell populations in cancer / Benjamin J. Daniel, Duane P. Jeansonne, Suzanne R. Thibodeaux, and Tyler J. Curiel -- Elimination of dendritic cells in cancer ? Viktor Umansky and Dirk Schadendorf -- Part II. Mechanisms of dendritic cell dysfunction in cancer -- Tumor-derived factors responsible for dendritic cell dysfunction / Alberto Pinzon-Charry and J. Alejandro López -- Tumor-derived exosomes as dendritic cell modulators / Roberta Valenti ... [et al.] -- Signaling pathways mediating dendritic cell dysfunction in cancer / Jing Yang and Qing Yi -- A role for STAT3 in dendritic cell regulation by tumor-derived factors / Dmitry I. Gabrilovich -- Tumor-associated inflammation and impact of dendritic cell function / Zoltan Pos ... [et al.] -- Changes in dendritic cells in cancer and aging / Annabelle Grolleau-Julius and Raymond L. Yung -- Stress, immunity and dendritic cells in cancer / Rachel Kohman and Alexander W. Kusnecov -- Cancer therapy and dendritic cell immunomodulation / Galina V. Shurin, Neil Amina, and Michael R. Shurin --Part III. Role of dendritic cells in tumor escape -- Role IDO in dendritic cell differentiation and function in cancer / Alexey Popov and Joachim L. Schultze -- Dendritic cells: from inducers of specific T-cell responses to promoters of angiogenesis / George Coukos and Fabian Benencia -- Protumorigenic function of dendritic cells / Anjli Kukreja -- Dendritic cell maturation versus polarization in tumor escape / Michael W. Lipscomb, Walter J. Storkus, and Amy K. Wesa -- Part IV. Dendritic cells in cancer: clinical aspects -- Trafficking of dendritic cells in the tumor environment / Zoya R. Yurkovetsky and Ghena N. Yurkovetsky -- Dendritic cells in tumor-draining lymph nodes / Alistair J. Cochran ... [et al.] -- Dendritic cell vaccines in cancer: obstacles to overcome / Ezra D. Mirvish, Rebecca G. Pomerantz, Louis D. Falo, and Larisa J. Geskin -- How best to generate dendritic cells from patients with cancer and how best to use them for immunotherapeutic purposes / Mark M. Aloysius, Richard A. Robins, and Oleg Eremin -- Genetically modified dendritic cells in cancer immunotherapy / Brian J. Morrison ... [et al] -- Dendritic cell tumors / Lourdes R. Ylagan -- Future directions in dendritic cell research in cancer / Madhav V. Dhodapkar.
  • Dermal tumors 2011, Springer
  • Desmoid tumors 2011, Springer
    Clinical Presentation of Desmoid Tumors -- Pathology of Desmoid Tumors -- APC/β-Catenin Deregulation in Desmoid Tumors: Important Implications for Diagnosis, Prognosis, and Therapy -- Imaging Techniques in Desmoid Tumors -- Surgical Management of Desmoid Tumors -- Systemic Therapy in the Treatment of Desmoid Tumors -- Radiation Therapy for Desmoid Tumors -- Interventional Radiology -- Introduction -- Desmoid Disease in Familial Adenomatous Polyposis -- Desmoid Tumor in Children and Adolescents: The Influence of Age -- Microarrays and High-Throughput Sequencing in Desmoid-Type Fibromatosis and Scar -- Desmoid Tumors: Are They Benign or Malignant? -- The Role of Patient Advocacy Groups in Rare Tumors Such as Desmoid Tumors.
  • The hedgehog signaling pathway in cancer / J. Vestergaard, Mads Bak, L.A. Larsen -- Rho GTPases and cancer / P. Buongiorno, B. Bapat -- Developmental biology of fibroblasts and neoplastic disease / D. Brouty-Boyé -- The extracellular matrix during normal development and neoplastic growth / J. Labat-Robert, L. Robert -- Wilms' tumor : starting off the kidney all over again? / M. Little -- Testicular teratomas : back to pluripotent stem cells / T. Kimura ... [et al.] / Tumor suppressors APC and VHL : gatekeepers of the intestine and kidney / R.H. Giles, E.E. Voest -- Hormonal and stromal regulation of normal and neoplastic prostatic growth / W.A. Ricke ... [et al.] -- Neoplastic growth through the developmental stages of the organism / A. Maciera-Coelho.
  • The Cancer Genome -- Mechanisms of Genomic Instability -- Epigenetics of Cancer -- Telomeres, Telomerase, and Cancer -- Cell Signaling Growth Factors and Their Receptors -- Cell Cycle -- Mechanisms of Cell Death -- Cancer Metabolism -- Angiogenesis -- Invasion and Metastasis -- Cancer Stem Cells -- Biology of Personalized Cancer Medicine -- Tobacco -- Cancer Susceptibility Syndromes -- DNA Viruses -- RNA Viruses -- Inflammation -- Chemical Factors -- Physical Factors -- Dietary Factors -- Obesity and Physical Activity -- Epidemiologic Methods -- Global Cancer Incidence and Mortality -- Trends in Cancer Mortality -- Surgical Oncology: General Issues -- Surgical Oncology: Laparoscopic Surgery -- Radiation Oncology -- Medical Oncology -- Assessment of Clinical Response -- Cancer Immunotherapy -- Health Services Research and Economics of Cancer Care -- Pharmacokinetics and Pharmacodynamics -- Pharmacogenomics -- Alkylating Agents -- Platinum Analogs -- Antimetabolites -- Topoisomerase-Interacting Agents -- Antimicrotubule Agents -- Targeted Therapy with Small Molecule Kinase Inhibitors -- Histone Deacetylase Inhibitors and Demethylating Agents -- Proteasome Inhibitors -- Poly(ADP-Ribose) Polymerase Inhibitors -- Miscellaneous Chemotherapeutic Agents -- Interferons -- Interleukin Therapy -- Antisense Agents -- Antiangiogenesis Agents -- Monoclonal Antibodies -- Endocrine Manipulation -- Preventive Cancer Vaccines -- Tobacco Dependence and Its Treatment -- Role of Surgery in Cancer Prevention -- Principles of Cancer Risk Reduction Intervention -- Retinoids, Carotenoids, and Other Micronutrients in Cancer Prevention -- Drugs and Nutritional Extracts for Cancer Risk Reduction (Chemoprevention) -- Principles of Cancer Screening -- Early Detection Using Proteomics -- Screening for Gastrointestinal Cancers -- Screening for Gynecologic Cancers -- Screening for Breast Cancer -- Screening for Prostate Cancer -- Screening for Lung Cancer -- Genetic Counseling -- Vascular Access and Specialized Techniques -- Interventional Radiology -- Functional Imaging -- Molecular Imaging --Photodynamic Therapy -- Biomarkers -- Design and Analysis of Clinical Trials -- Molecular Biology of Head and Cancers -- Treatment of Head and Neck Cancer -- Rehabilitation after Treatment of Head and Neck Cancer -- Molecular Biology of Lung Cancer -- Non-Small Cell Lung Cancer -- Small Cell and Neuroendocrine Tumors of the Lung -- Neoplasms of the Mediastinum -- Molecular Biology of the Esophagus and Stomach -- Cancer of the Esophagus -- Cancer of the Stomach -- Molecular Biology of Pancreas Cancer -- Cancer of the Pancreas -- Molecular Biology of Liver Cancer -- Cancer of the Liver -- Cancer of the Biliary Tree -- Cancer of the Small Intestine -- Gastrointestinal Stromal Tumor -- Molecular Biology of Colorectal Cancer -- Cancer of the Colon -- Cancer of the Rectum -- Cancer of the Anal Region -- Molecular Biology of Kidney Cancer -- Cancer of the Kidney -- Molecular Biology of Bladder Cancer -- Cancer of the Bladder, Ureter, and Renal Pelvis -- Molecular Biology of Prostate Cancer -- Cancer of the Prostate -- Cancer of the Urethra and Penis -- Cancer of the Testis -- Molecular Biology of Gynecologic -- Cancer of the Cervix, Vagina, and Vulva -- Cancers of the Uterine Body -- Gestational Trophoblastic Neoplasms -- Ovarian Cancer, Fallopian Tube Carcinoma, and Peritoneal Carcinoma -- Molecular Biology of Breast Cancer -- Malignant Tumors of the Breast -- Molecular Biology of Endocrine Tumors -- Thyroid Tumors -- Parathyroid Tumors -- Adrenal Tumors -- Pancreatic Neuroendocrine Tumors -- Neuroendocrine (Carcinoid) Tumors and the Carcinoid Syndrome -- Multiple Endocrine Neoplasias -- Molecular Biology of Soft Tissue Sarcoma -- Soft Tissue Sarcoma -- Sarcomas of Bone -- Cancer of the Skin -- Molecular Biology of Cutaneous Melanoma -- Cutaneous Melanoma -- Molecular Biology of Central Nervous System Tumors -- Neoplasms of the Central Nervous System -- Molecular Biology of Childhood Cancers -- Solid Tumors of Childhood -- Leukemias and Lymphomas of Childhood -- Molecular Biology of Lymphomas -- Hodgkin Lymphoma -- Non-Hodgkin Lymphomas -- Cutaneous Lymphomas --Primary Central Nervous System Lymphoma -- Molecular Biology of Acute Leukemias -- Management of Acute Leukemias -- Molecular Biology of Chronic Leukemias -- Chronic Myelogenous Leukemia -- Chronic Lymphocytic Leukemias -- Myelodysplastic Syndromes -- Plasma Cell Neoplasms -- Cancer of Unknown Primary Site -- Benign and Malignant Mesothelioma -- Peritoneal Surface Malignancy -- Intraocular Melanoma -- AIDS-Related Malignancies -- Transplantation-Related Malignancies -- Superior Vena Cava Syndrome -- Increased Intracranial Pressure -- Spinal Cord Compression -- Metabolic Emergencies -- Metastatic Cancer to the Brain -- Metastatic Cancer to the Lung -- Metastatic Cancer to the Liver -- Metastatic Cancer to the Bone -- Malignant Effusions of the Pleura and the Pericardium -- Malignant Ascites -- Paraneoplastic Syndromes -- Autologous Stem Cell Transplantation -- Allogeneic Stem Cell Transplantation -- Infections in the Cancer Patient -- Leukopenia and Thrombocytopenia -- Cancer-Associated Thrombosis -- Nausea and Vomiting -- Diarrhea and Constipation -- Oral Complications -- Pulmonary Toxicity -- Cardiac Toxicity -- Hair Loss -- Gonadal Dysfunction -- Fatigue -- Second Primary Cancers -- Neurocognitive Effects -- Cancer Survivorship -- Management of Cancer Pain -- Nutritional Support -- Sexual Problems -- Psychological Issues in Cancer -- Communicating News to the Cancer Patient -- Specialized Care of the Terminally Ill -- Community Resources -- Rehabilitation of the Cancer Patient -- Regulatory Issues -- Health Disparities in Cancer -- Cancer Information on the Internet -- Complementary, Alternative, and Integrative Therapies in Cancer Care.
  • Diabetes and cancer 2008, Karger
  • Morphologic Patterns -- Common Diagnostic Discrepancies -- Frozen Section of Ovarian Lesions -- Surface Epithelial Tumors: Pathology Introduction -- Surface Epithelial Tumors: Clinical Introduction -- Pathology of Serous Tumors -- Pathology of Endometrioid Tumors -- Pathology of Clear Cell Tumors -- Pathology of Mucinous Tumors -- Uncommon Epithelial Ovarian Tumors -- Metastatic Tumors -- Germ Cell and Sex Cord Stromal Tumors: Clinical Introduction -- Pathology of Germ Cell Tumors -- Sex Cord Stromal Tumors of the Ovary -- Pathology of Mesenchymal and Hematopoietic Tumors -- Tumors of Uncertain Histogenesis -- Fallopian Tube and Peritoneum -- Familial Cancer and Prophylactic Surgery -- Peritoneal Cytology.
  • 1. Gene Signatures and Soft Tissue Sarcomas: Status of Art and Perspectives / Bruno Vincenzi, Anna Maria Frezza, Daniele Santini, and Giuseppe Tonini -- 2. Heterogeneity of Breast Cancer: Gene Signatures and Beyond / Gaia Schiavon, Marcel Smid, Gaorav P. Gupta, Stefania Redana, Daniele Santini, and John W.M. Martens -- 3. Gene Signatures in CRC and Liver Metastasis / Daniele Fanale, Lidia Corsini, Sergio Rizzo, and Antonio Russo -- 4. Gene Signatures in Gastrointestinal Stromal Tumors / Piotr Rutkowski, Giuseppe Badalamenti, Laura La Paglia, Joanna Przybył, and Maria Debiec-Rychter -- 5. Pancreatic Cancer Genetics / Juan Iovanna, Ezequiel Luis Calvo, Jean Charles Dagorn, and Nelson Dusetti -- 6. Diagnostic, Prognostic, and Therapeutic Value of Gene Signatures in Non-Small Cell Lung Cancer / Rafael Rosell, Miquel Taron, Christian Diego Rolfo, Delvys Rodriguez-Abreu, and Jia Wei -- 7. Gene Signatures in Gastric Cancer / Laura Ottini, Mario Falchetti, and Gabriella Nesi -- 8. Gene Signatures in Colorectal Cancer / Alessandro Lugli and Inti Zlobec -- 9. The Role of Epigenetics in Cancer: From Molecular Function to High-Throughput Assays / Aleksandra Pekowska, Joaquin Zacarias-Cabeza, Jinsong Jia, Pierre Ferrier, and Salvatore Spicuglia -- 10. Primary Epithelial Ovarian Neoplasms: New Concepts Concerning Origin, Pathogenesis and Classification Based on Morphology, Immunomarkers, Molecular Features, and Gene Expression Studies / Bernard Czernobilsky, Leonor Leider-Trejo, Daniele Fanale, and Antonio Russo -- 11. Thyroid Carcinoma: Molecular Signature by Histotype-Specific Mutations and Gene Expression Patterns / Umberto Malapelle, Claudio Bellevicine, Lajos Pustzai, and Giancarlo Troncone.
  • Diet and cancer v. 1-, 2010-, Springer
  • Radiologic and pathologic approach to bone tumors -- Bone-forming (osteogenic) lesions -- Cartilage (chondrogenic) lesions -- Fibrogenic, fibroosseous, and fibrohistiocytic lesions -- Round cell lesions -- Vascular lesions -- Miscellaneous tumors and tumor-like lesions -- Metastases -- Tumors and tumor-like lesions of the joints.
  • The biology, behavior and management of diffuse low-grade gliomas (DLGG) in adults have been matters of controversy for many decades. However, recent technical and conceptual advances in genetics, imaging and treatments have paved the way towards individualized management. In addition, advancing knowledge of brain processing means that it is possible to take into consideration the interaction between the disease (low-grade glioma) and the host (the brain) and thus to modulate the therapeutic strategies with the goal to increase the median survival as well as to improve the quality of life. Diffuse Low-Grade Gliomas in Adults: Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualized therapy for this kind of tumor. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book. This book uniquely focuses on addressing diffuse low-grade gliomas in adults and is a valuable resource for medical oncologists, neuro-oncologists and neurologists.
  • Breast anatomy and development -- Molecular mechanisms regulating breast development -- Stem cells in breast development and carcinogenesis: concepts and clinical perspectives -- Physical examination of the breast -- Management of the palpable breast mass -- Management of disorders of the ductal system and infections -- Management of breast pain -- Abnormalities of the breast in pregnancy and lactation -- Management of gynecomastia -- Pathology of benign breast disorders -- Screening for breast cancer -- Imaging analysis: mammography -- Breast ultrasound -- Imaging analysis: magnetic resonance imaging -- Imaging: new techniques -- Image-guided biopsy of nonpalpable breast lesions -- Management summary on breast imaging -- Inherited genetic factors and breast cancer -- Genetic testing and management of patients with hereditary breast cancer -- Nongenetic factors in the causation of breast cancer -- Management of other high risk patients -- Chemoprevention: clinical aspects -- Pathology and biological features of premalignant breast disease -- Lobular carcinoma in situ: biology and pathology -- Lobular carcinoma in situ: clinical management -- Ductal carcinoma in situ and microinvasive carcinoma -- Breast cancer genomics -- Pathology of invasive breast cancer -- Clinical aspects of estrogen and progesterone receptors -- ERBB2 testing: assessment of status for targeted therapies -- Prognostic and predictive markers -- Gene arrays, prognosis, and therapeutic interventions -- Bone marrow micrometastases and circulating tumor cells -- Evaluation of patients for metastasis prior to primary therapy -- Staging of breast cancer -- Mastectomy -- Breast-conserving therapy: conventional whole breast irradiation -- Breast-conserving therapy: accelerated partial breast irradiation -- Breast reconstruction -- Local therapy for the breast and chest wall -- Sentinel lymph node dissection -- Axillary dissection -- Axillary irradiation -- Preserving and restoring function after local treatment -- Lymphedema -- Treatment of the axilla and other regional nodes -- Postmastectomy radiation therapy -- Adjuvant systemic therapy: endocrine therapy -- Adjuvant systemic therapy: chemotherapy --Adjuvant systemic therapy: chemoendocrine -- Adjuvant treatment of ERBB2 positive breast cancer -- Adjuvant systemic therapy: bisphosphonates -- Lifestyle issues in breast cancer survivors -- Management of menopausal symptoms in breast cancer survivors -- Side effects of systemic therapy: neurocognitive, cardiac, and secondary malignancies -- Pharmacogenomics of systemic therapy of breast cancer -- Guidelines for adjuvant systemic therapy -- Preoperative therapy for operable breast cancer -- Preoperative endocrine therapy for operable breast cancer -- Local-regional therapy considerations in patients receiving preoperative chemotherapy -- Locally advanced breast cancer -- Inflammatory breast cancer -- Management summary on preoperative systemic therapy -- Male breast cancer -- Phyllodes tumors -- Paget's disease -- Nonepithelial malignancies of the breast -- Breast cancer during pregnancy and subsequent pregnancy in breast cancer survivors -- Occult primary cancer with axillary metastases -- Surveillance of patients following primary therapy -- Surgery for the primary in patients with distant metastases -- Local-regional recurrence after breast-conservation treatment or mastectomy -- Treatment of metastatic breast cancer: endocrine therapy -- Treatment of metastatic breast cancer: chemotherapy -- Treatment of HER2-overexpressing metastatic breast cancer -- End-of-life considerations in patients with breast cancer -- Management summary for metastatic disease for the care of patients with metastatic disease -- Angiogenesis inhibition in breast cancer -- Tyrosine kinase inhibitors -- Newer targeted therapy in breast cancer -- Brain metastases -- Epidural metastases -- Leptomeningeal metastasis -- Brachial plexopathy in patients with breast cancer -- Ocular metastases -- Malignant effusions -- Management of discrete pulmonary nodules -- Management of lsolated liver metastases -- Bone-directed therapy and breast cancer: bisphosphonates, monoclonal anitbody, and radionuclides -- Local management of bone metastases -- Breast cancer in older women -- Breast cancer in younger women -- Breast cancer in minority women -- Nursing care in patient management and quality of life -- Psychosocial adaptation during and after breast cancer -- Reproductive issues in breast cancer survivors -- Medical legal aspects of breast cancer evaluation -- Cost and cost-effectiveness considerations.
  • The HIF-2[alpha]-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization / A. Pietras, A.S. Johnsson and S. Pahlman -- Hypoxia and hypoxia inducible factors in cancer stem cell maintenance / Z. Li and J.N. Rich -- Role of carcinoma-associated fibroblasts and hypoxia in tumor progression / A.J. Giaccia and E. Schipani -- The role of hypoxia regulated microRNAs in cancer / R. McCormick ... [et al.] -- Oxygen sensing: A common crossroad in cancer and neurodegeneration / A. Quaegebeur and P. Carmeliet -- Hypoxia-inducible factors as essential regulators of inflammation / H.Z. Imtiyaz and M.C. Simon -- Hypoxia and metastasis in breast cancer / H. Rundqvist and R.S. Johnson.
  • DNA damage response 2009, Springer
    DNA Damage Sensing and Signaling / Daniel Durocher -- Signaling at Stalled Replication Forks / Daniel A. Mordes and David Cortez -- An Oncogene-Induced DNA Replication Stress Model for Cancer Development / Thanos D. Halazonetis -- Cellular Responses to Oxidative Stress / Inbal Dar and Ari Barzilai -- Cell Cycle Regulation and DNA Damage / Ryo Sakasai and Randal S. Tibbetts -- Chromatin Modifications Involved in the DNA Damage Response to Double Strand Breaks / Julia Pagan, Emma Bolderson, Mathew Jones and Kum Kum Khanna -- Telomere Metabolism and DNA Damage Response / Tej K. Pandita -- DNA Double Strand Break Repair: Mechanisms and Therapeutic Potential / Laura M. Williamson, Chris T. Williamson and Susan P. Lees-Miller -- DNA Base Excision Repair: A Recipe for Survival / Rabindra Roy and Sankar Mitra -- DNA Damage Tolerance and Translesion Synthesis / Alan R. Lehmann -- Nucleotide Excision Repair: from DNA Damage Processing to Human Disease / Mischa G. Vrouwe and Leon H.F. Mullenders -- Chromosomal Single-Strand Break Repair / Keith W. Caldecott -- Mouse Models of DNA Double Strand Break Repair Deficiency and Cancer / Sachin Katyal and Peter J. McKinnon -- Cancer Biomarkers Associated with Damage Response Genes / Anne E. Kiltie, Marie Fernet and Janet Hall -- Linking Human RecQ Helicases to DNA Damage Response and Aging / Wen-Hsing Cheng, Byungchan Ahn and Vilhelm A. Bohr -- Single-Stranded DNA Binding Proteins Involved in Genome Maintenance / Derek J. Richard and Kum Kum Khanna -- The Fanconi anemia-BRCA Pathway and Cancer / Toshiyasu Taniguchi -- BRCA1 and BRCA2: Role in the DNA Damage Response, Cancer Formation and Treatment / Kienan Savage and D. Paul Harkin.
  • DNA methylation : three decades in search of function / Aharon Razin -- Epigenetic mechanisms of gene regulation : relationships between DNA methylation, histone modification, and chromatin structure / Keith D. Robertson -- DNA hypo- vs. hypermethylation in cancer : tumor specificity, tumor progression, and therapeutic implications / Melanie Ehrlich and Guanchao Jiang -- DNA methylation in urological cancers / Wolfgang A. Schulz and Hans-Helge Seifert -- DNA methylation in colorectal cancer / Jeremy R. Jass ... [et al.] -- CpG island hypermethylation of tumor suppressor genes in human cancer : concepts, methodologies and uses / Michel Herranz and Manel Esteller -- The loss of methyl groups in DNA of tumor cells and tissues : the immunochemical approach / Alain Niveleau ... [et al.] -- Identifying clinicopathological association of DNA hypermethylation in cancers using CpG island microarrays / Susan H. Wei ... [et al.] -- Methylation analysis in cancer : (epi)genomic fast track from discovery to clinical routine / Carolina Haefliger, Sabine Maier and Alexander Olek --Regulation of DNA methyltransferases in cancer / Nancy Detich and Moshe Szyf -- Inhibition of poly(ADP-ribosyl)ation allows DNA hypermethylation / Anna Reale ... [et al.] -- The role of active demethylation in cancer and its therapeutic potential / Moshe Szyf ... [et al.] -- Purine analogues and their role in methylation and cancer chemotherapy / Katherine L. Seley and Sylvester L. Mosley -- DNA methyltransferase inhibitors : paving the way for epigenetic cancer therapeutics / Gregory K. Reid and A. Robert MacLeod -- Preclinical and clinical studies on 5-aza-2'-deoxycytidine, a potent inhibitor of DNA methylation, in cancer therapy / Richard L. Momparler -- Anticancer gene therapy by in vivo DNA electrotransfer of MBD2 antisense / Pascal Bigey and Daniel Scherman.
  • Regulation of chromatin and DNA-methylation patterns in blood cell development / C. Bonifer, P. Lefevre, and H. Tagoh -- Methylation dynamics in the early mammalian embryo : implications of genome reprogramming defects for development / T. Haaf -- Epigenetic regulation in drosophila / F. Lyko ... [et.al.] -- Epimutations in human disease / B. Horsthemke -- Epigenotypes of latent herpesvirus genomes / J. Minarovits -- Epigenetics of complex diseases : from general theory to laboratory experiments / A. Schumacher and A. Petronis -- MSL proteins and the regulation of gene expression / S. Rea and A. Akhtar -- DNA methylation profiles of female steroid hormone-driven human malignancies / M. Campan, D.J. Weisenberger, and P.W. Laird -- Genome-wide analysis of DNA methylation changes in human malignancies / C. Plass and D.J. Smiraglia -- Decreased fidelity in replicating DNA methylation patterns in cancer cells leads to dense methylation of a CpG island / N. Watanabe ... [et.al.] -- Methylation of endogenous human retroelements in health and disease / W. A. Schulz, C. Steinhoff, and A.R. Florl -- Cancer-linked DNA hypomethylation and its relationship to hypermethylation / M. Ehrlich.
  • Introduction and overview of current targets: bench to clinic / Mark R. Kelley -- 2. MGMT a critical DNA repair gene target for chemotherapy resistance / Stanton L. Gerson and Lili Liu -- 3. Blockade of base excision repair: inhibition of small lesions results in big consequences to cancer cells / Melissa Fishel and Carlo Vascotto -- 4. PARP inhibitors -- scientific rationale and clinical development for cancer / Ruth Plummer, Nicola J. Curtin and Yvette Drew -- 5. Inhibiting selective DNA polymerases for therapeutic intervention / Anthony J. Berdis -- 6. Targeting the nucleotide excision repair pathway for therapeutic applications / John Turchi and Stephan M. Patrick -- 7. Homologous recombination and ATM/ATR targets / Henning Willers, Lee Zou and Heike N. Pfaffle -- 8. DNA double strand break repair by nonhomologous end joining and its clinical relevance / Michael Weinfeld and Susan Lees-Miller -- 9. Defective MMR-c-Abl-p73-GADD45alpha expression in cancer chemoresistance / David Boothman and Long Shan Li -- 10. DNA repair signaling targets / Susan Ashwell -- 11. Redox regulation of DNA repair and therapeutic / Millie M. Georgiadis -- 12. Personalized cancer medicine: DNA repair alterations is a promising predictive marker in cancer / Srinivasan Madhusudan -- 13. The role of DNA damage and repair in neurotoxicity caused by cancer therapies / Michael R. Vasko -- 14. Future directions with DNA repair inhibitors / Mark R. Kelley.
  • Introduction and historical perspective / Patrick Forterre -- Human DNA topoisomerase I : structure, enzymology and biology / James J. Champoux -- Mitochondrial topoisomerases / Ilaria Dalla Rosa, Yves Pommier, and Hongliang Zhang -- Structure and mechanism of eukaryotic type IIA topoisomerases / James M. Berger and Neil Osheroff -- Essential functions of topoisomerase III-alpha in the nucleus and mitochondria / Stefanie Hartman Chen, Jianhong Wu, and Tao-shih Hsieh -- DNA topoisomerase I and illegitimate recombination / Céline Auzanneau and Philippe Pourquier -- Topoisomerase-induced DNA damage / Yves Pommier and Neil Osheroff -- Topoisomerases and carcinogenesis : topoisomerases III-alpha and BLM / Mounira Amor-Guéret and Jean-François Riou -- Topoisomerases inhibitors : a paradigm for interfacial inhibition / Christophe Marchand and Yves Pommier -- Topoisomerases I inhibitors : chemical biology / Beverly A. Teicher -- Topoisomerases II inhibitors : chemical biology / Anna Rogojina ... [et al.] -- Topoisomerases I inhibitors : current use and prospects / Yan Makeyev ... [et al.] -- Topoisomerases II inhibitors : current use and prospects / Olivier Mir ... [et al.] -- Transcriptional stress by camptothecin : mechanisms and implications for the drug antitumor activity / Giovanni Capranico ... [et al.] -- Mechanisms regulating cellular responses to DNA topoisomerases I-targeted agents / Piero Benedetti and Mary-Ann Bjornsti -- Tyrosyl-DNA-phosphodiesterase / Thomas S. Dexheimer ... [et al.] -- Ubiquitin and ubiquitin-like proteins in repair of topoisomerases-mediated DNA damage / Shyamal D. Desai -- Repair of topoisomerases II-mediated DNA damage : fixing DNA damage arising from a protein covalently trapped on DNA / John L. Nitiss ... [et al.] -- Topoisomerases and apoptosis / Olivier Sordet and Stéphanie Solier.
  • Multidrug Resistance Mediated by MDR-ABC Transporters / Gergely Szakács ... [et al.] -- Metastasis and Drug Resistance / Dominic Fan ... [et al.] -- The Role of Autophagy and Apoptosis in the Drug Resistance of Cancer / Tomohisa Yokoyama ... [et al.] -- Mechanisms of Resistance to targeted Tyrosine Kinase Inhibitors / Stacey J.Baker, E. Premkumar Reddy -- Targeting Transglutaminase-2 to overcome Chemoresistance in Cancer Cells / Kapil Mehta, Jansina Y. Fok -- Extracellular Matrix-Mediated Drug Resistance / P.S. Hodkinson, Tariq Sethi -- Oxidative Stress and Drug Resistance in Cancer / Dunyaporn Trachootham, Wan Zhang, Peng Huang -- Nuclear Factor-kB and Chemoresistance / Ajaikumar B.Kunnumakkara, Preetha Anand, Bharat B. Aggarwal -- Drug Resistance and the Tumor Suppressor p53 : The Paradox of Wild-Type Genotype in Chemorefractory Cancers / Zahid H. Siddik -- Resistance to Differentiation Therapy / Bulent Ozpolat -- MicroRNAs and Drug Resistance / Elisa Barbarotto, George A. Calin -- Molecular Signatures of Drug Resistance / Melissa A. Troester, Jason I. Herschkowitz, Katherine A. Hoadley -- Assessment of Drug Resistance in Anticancer Therapy by Nuclear Imaging / Natalie Charnley, Catharine West, Pat Price -- Overcoming Drug Resistance by Phytochemicals / Marion M. Chan, Dunne Fong.
  • Dynamics of cancer 2007, NCBI Bookshelf
    Age of cancer incidence -- Multistage progression -- History of theories -- Progression dynamics -- Theory I -- Theory II -- Genetics of progression -- Carcinogens -- Aging -- Inheritance -- Stem cells : tissue renewal -- Stem cells : population genetics -- Cell lineage history.
  • Clinically relevant study end points in rectal cancer -- Neoadjuvant treatment in rectal cancer : do we always need radiotherapy or can we risk assess locally advanced rectal cancer better? -- Treatment dilemmas in patients with synchronous colorectal liver metastases -- Pancreatic surgery : beyond the traditional limits -- Adjuvant therapy for pancreatic cancer -- Radiotherapy of the pancreas : state of the art in 2012 -- Adenocarcinoma of the GEJ : gastric or oesophageal cancer? -- Why is there a change in patterns of GE cancer? -- Endoscopic treatment for esophageal squamous cell carcinoma -- Open or minimally invasive resection for oesophageal cancer? -- Choosing the best treatment for esophageal cancer -- Multimodal therapy of GEJ cancer : when is the definitive radiochemotherapy the treatment of choice? -- Radiotherapy of gastroesophageal junction cancer -- Optimizing neoadjuvant chemotherapy through the use of early response evaluation by positron emission tomography -- Optimal surgery for gastric cancer : is more always better? -- Can adjuvant chemoratiotherapy replace extended lymph node dissection in gastric cancer? -- Predicting the response to chemotherapy in gastric adenocarcinoma : who benefits from neoadjuvant chemotherapy? -- Prediction of response and prognosis by a score including only pretherapeutic parameters in 410 neoadjuvant treated gastric cancer patients -- Adjuvant chemotherapy : an option for Asian patients only? -- Selecting the best treatment for an individual patient.
  • ECTO-NOX proteins 2013, Springer
  • EGF receptor family 2004, ScienceDirect
  • Electric Cell-Substrate Impedance Sensing Concept to Commercialization /Ivar Giaever and Charles R. Keese --Protein Kinase C Isoforms in the Formation of Focal Adhesion Complexes: Investigated by Cell Impedance /Havovi Chichger, Katie L. Grinnell and Elizabeth O. Harrington --ECIS as a Tool in the Study of Metastasis Suppressor Genes: Epithelial Protein Lost In Neoplasm (EPLIN) /Andrew J. Sanders, Vladimir M. Saravolac, Malcolm D. Mason and Wen G. Jiang --Electrical Cell-Substrate Impedance Sensing for Measuring Cellular Transformation, Migration, Invasion, and Anticancer Compound Screening /Bryan Plunger, Chang Kyoung Choi and Tim E. Sparer --Epithelial-Mesenchymal Transition and the Use of ECIS /Jane Lane and Wen G. Jiang --Cell Growth and Cell Death Studied by Electric Cell-Substrate Impedance Sensing /Judith Anthea Stolwijk, Stefanie Michaelis and Joachim Wegener --Tight Junctions in Cancer Metastasis and Their Investigation Using ECIS (Electric Cell-Substrate Impedance Sensing) /Tracey A. Martin and Wen G. Jiang --Epithelial Wound Healing and the Effects of Cytokines Investigated by ECIS: Electric Cell-Substrate Impedance Sensing in Epithelial Research /Katalin Szaszi, Matthew Vandermeer and Yasaman Amoozadeh --Tumour-Endothelial and Tumour-Mesothelial Interactions Investigated by Impedance Sensing Based Cell Analyses /Wen G. Jiang, Lin Ye, Haiying Ren, Ann Kift-Morgan and Nicholas Topley, et al. --Application of Electric Cell-Substrate Impedance Sensing in Evaluation of Traditional Medicine on the Cellular Functions of Gastric and Colorectal Cancer Cells /Lin Ye, Ke Ji, Jiafu Ji, Rachel Hargest and Wen G. Jiang --Electric Cell-Substrate Impedance Sensing as a Screening Tool for Wound Healing Agents /Cheuk Lun Liu, Jacqueline Chor Wing Tam, Andrew J. Sanders, David G. Jiang and Chun Hay Ko, et al. --ECIS, Cellular Adhesion and Migration in Keratinocytes /David C. Bosanquet, Keith G. Harding and Wen G. Jiang --Current and Future Applications of ECIS Models to Study Bone Metastasis /Lin Ye, Sivan M. Bokobza, Howard G. Kynaston and Wen G. Jiang.
  • Elephant in the room 2012, Springer
    Rick's Big Adventure -- All My Trials -- Fish Ate My Cancer -- Smoker's Cough -- Conference With Counsel -- Coming Through -- Here's Henry -- Why Me? -- How Do They Know What I've Got? -- Doctors and Cancer: Firewall.
  • V. 1. A-B -- v. 2. C -- v. 3. D-G -- v. 4. H-L -- v. 5. M-O -- v. 6. P-R -- v. 7. S-Z.
  • Endocrine neoplasia 2010, Springer
    Part. I Thyroid.-- Biology of thyroid oncogenesis / Insoo Suh, Electron Kebebew.-- Evaliation of the thyroid nodule / Dina M. Elaraj.-- Differentiated thyroid cancers of follicular cell origin / Linwah Yip, Sally E. Carty.-- Sporadic medullary thyroid cancer / Adrian Harvey, Janice L. Pasieka.-- Anaplastic thyroid cancer / Alan P.B. Dackiw.-- Part II. Parathyroid.-- Primary hyperparathyroidism / Kaitlyn J. Kelly, Herbert Chen, Rebecca S. Sippel.-- Parathyromatosis and parathyroid cancer / Wen T. Shen.-- Part III. Incidentaloma / Jacob Malem, Insoo Suh, Quan-Yang Duh.-- Pheochromocytoma and paraganglioma / Goswin Y. Meyer-Rochow, Stan B. Sidhu.-- Functional cortical neoplasms / Ali Zarrinpar, Michael W. Yeh.-- Adrenocortical carcinoma / Patsy S.H. Soon, Stan B. Sidhu.-- Part IV. Pnacreatic neuroendocrine tumors.-- Gastrinoma / Anthony J. Chambers, Janice L. Pasieka.-- Insulinoma / Kimberly Vanderveen, Clive Grant.-- Rare neuroendocrine tumors of the pancreas / Shih-Ping Cheng, Gerard M. Doherty.-- Part V. Multiple endocrine neoplasia.-- Menin gene / Hsin-Chieh Jennifer Shen, Steven K. Libutti.-- Multiple endocrine neoplasia type I: clinical manifestations and management / Anathea C. Powell, Steven K. Libutti.-- RET protooncogene / Amber L. Traugott, Jeffrey F. Moley.-- Multiple endocrine neoplasia type 2: clinical manifestations and management / Amber L. Traugott, Jeffrey F. Moely.
  • Multiple endocrine neoplasia type 1 / Agarwal, S.K. -- Multiple endocrine neoplasia type 2 / Lodish, M. -- Von Hippel-Lindau syndrome / Chou, A. ... [et al.] -- Carney complex -- Espiard, S., Bertherat, J. -- Multiple endocrine neoplasia type 4 / Lee, M., Pellegata, N.S. -- Novel hereditary forms of pheochromocytomas and paragangliomas / Dahia, P.L.M. -- Carney triad / Carney, J.A. -- Genetics of pituitary adenomas / Gadelha, M.R. ... [et al.] -- Clinical behavior and genetics of nonsyndromic, familial nonmedullary thyroid cancer / Bauer, A.J. -- Genetic defects associated with familial and sporadic hyperparathyroidism / Hendy, G.N., Cole, D.E.C. -- Endocrine tumors associated with neurofibromatosis type 1, Peutz-Jeghers syndrome, and other familial neoplasia syndromes / Kalkan, E., Waguespack, S.G.
  • Hypopituitarism following radiotherapy revisited / Darzy, K.H., Shalet, S.M. -- Alterations in pubertal timing following therapy for childhood malignancies / Armstrong, G.T., Chow, E.J., Sklar, C.A. -- Obesity during and after treatment for childhood cancer / Reilly, J.J. -- Metabolic disorders / Gregory, J.W. -- Bone and bone turnover / Crofton, P.M. -- Male fertility and strategies for fertility preservation following childhood cancer treatment / Mitchell, R.T. ... [et al.] -- Fertility in female childhood cancer survivors / De Bruin, M.L. ... [et al.] -- Long-term follow-up of survivors of childhood cancer / Edgar, A.B. ... [et al.].
  • Current status of the prevention and early diagnosis of endometrial adenocarcinoma -- The value of endometrial cytology -- Techniques of endometrial cytology -- Techniques of endometrial histopathology -- New techniques for the diagnosis of endometrial pathology -- Cytology of the normal endometrium - cycling and postmenopausal -- Benign endometrial lesions -- Cytopathology of endometrial hyperplasias -- Cytopathology of endometrial adenocarcinoma -- Cytopathology of the non-epithelial malignant tumors of the uterine corpus.
  • Endoscopic oncology 2006, Springer
    Barrett's esophagus : screening, diagnosis, and management / Glenn M. Eisen -- Endoscopic screening for squamous cell carcinoma of the esophagus / Brian C. Jacobson -- Image enhancement endoscopy / Stephan M. Wildi and Michael B. Wallace -- Staging of esophageal cancer / Jason Vollweiler and Gregory Zuccaro, Jr. -- Endoscopic therapy for early esophageal cancer and premalignant lesions in Barrett's esophagus / Granapathy A. Prasad and Kenneth K. Wang -- Endoscopic therapy for advanced esophageal cancer / Sanjay Jagannath and Marcia I. Canto -- Radiological imaging of the upper gastrointestinal tract / Marc S. Levine -- Esophageal cancer therapy : surgery, radiation, and chemotherapy / John M. Holland and Christopher A. Canning -- Premalignant lesions of the stomach / Omid A. Shaye and Andrew Ippoliti -- Gastric polyps / George A. Makar and Gregory G. Ginsberg -- Endoscopic ultrasound for staging gastric cancer / Gregory Olds and Amitabh Chak -- Endoscopic treatment for gastric cancer / Takuji Gotoda and Roy M. Soetikno -- Diagnosis and management of gastrointestinal lymphoma / John G. Kuldau, Peter R. Holman, and Thomas J. Savides -- Gastrointestinal stromal tumors / Raquel E. Davila -- Carcinoid tumors / Wilscott E. Naugler and Gordon C. Hunt -- Medical and surgical therapy for gastric cancer / Diane Hershock -- Colorectal cancer screening / Jason A. Dominitz and William M. Grady --Polyposis and familial cancer syndromes / Fernando S. Velayos, Madhulika G. Varma, and Jonathan P. Terdiman -- Endoscopic colon surveillance : post-polypectomy, post-colorectal cancer resection, and inflammatory bowel disease / Douglas B. Nelson and Mandeep S. Sawhney -- Endoscopic ultrasound for staging rectal and anal cancer / Deepak V. Gopal -- Endoscopic therapy of colorectal carcinoma / Vaman Jakribettuu and Yang K. Chen -- Radiological imaging of the lower gastrointestinal tract / Steven E. Rubesin -- Current status of colorectal cancer therapy / John Strother ... [et al.] -- Cystic neoplasms of the pancreas / William R. Brugge -- Diagnosis and evaluation of pancreatic ductal adenocarcinoma / Kenneth H. Yu and Nuzhat A. Ahmad -- Adenocarcinoma of the pancreas : endoscopic palliation / Georgios I. Papachristou, Kevin McGrath, and Adam Slivka -- Pancreatic neuroendocrine tumors / Erik-Jan Wamsteker and James M. Scheiman -- Endoscopic diagnosis and management of cholangiocarcinoma / Vanessa M. Shami and Irving Waxman -- Ampullary neoplasia / Ian D. Norton -- Magnetic resonance imaging of neoplasms of the pancreatobiliary system / Evan S. Siegelman and Wendy C. Hsu -- Medical and surgical therapy of pancreatic cancer / Weijing Sun, Jon Morris, and Jeffrey Drebin -- Endoscopic ultrasound for thoracic disease / Timothy Woodward, Massimo Raimondo, and Michael B. Wallace.
  • Endourooncology 2005, Springer
    Merging of endourology and oncology: endourooncology / A. El-Hakim, B.R. Lee, and A.D. Smith -- Surgical robots and three-dimensional displays for computer-aided surgery / T. Dohi -- Robot-assisted (Da Vinci) urologic surgery: an emerging frontier / A.K. Hemal and M. Menon -- Robotic surgery assisted by the ZEUS system / M. Eto and S. Naito -- Telesurgery: remote monitoring and assistance laparoscopy / T. Inagaki, S.B. Bhayani, and L.R. Kavoussi -- Remote percutaneous renal access using a telesurgical robotic system / B. Challacombe, L. Kavoussi, and D. Stoianovici -- Radiofrequency ablation for percutaneous treatment of malignant renal tumors / S. Kanazawa, T. Iguchi, K. Yasui, H. Mimura, T. Tsushima, and H. Kumon -- High-intensity focused ultrasound for noninvasive renal tumor thermoablation / A. Häckr, M.S. Michel, and K.U. Köhrmann -- High-intensity focused ultrasound (HIFU) for the treatment of localized prostate cancer / T. Uchida, H. Ohkusa, H. Yamashita, and Y. Nagata -- Renal cryoablation / K. Nakagawa and M. Murai -- Prostate cryoablation / B.J. Donnelly and J.C. Rewcastle -- Tumor control outcome and tolerance of permanent interstitial implanation for patients with clinically localized prostate cancer / Y. Nasu, F. Abarzua, and H. Kumon.
  • Energy balance and cancer v. 1-, 2011-, Springer
  • Epidemiologic basis of the role of environmental endocrine disruptors in breast cancer /Robert A. Hiatt --Puberty as a window of susceptibility /Frank M. Biro and Mary S. Wolff --In search of the optimal experimental model /Irma H. Russo and Jose Russo --Early life exposure to bisphenol A and breast neoplasia /Maricel V. Maffini, Carlos Sonnenschein, and Ana M. Soto --Endocrine disruptors affect the genomic profile of the rat mammary gland at different developmental stages /Ricardo Lopez de Cicco ... [et al.] --Proteomic basis for the increased susceptibility of the mammary gland to carcinogenesis after perinatal exposure to bisphenol A /Sarah Jenkins ... [et al.] --Dioxin as an environmental pollutant and its role in breast cancer /Stephen Safe, Kelcey Walker, and Shu Zhang --Mammary gland as a sensitive tissue to developmental exposures of perfluorooctanoic acid (PFOA) in the mouse /Sally S. White ... [et al.] --Atropine : an environmental endocrine disruptor that alters mammary gland development and tumor susceptibility /Jennifer L. Rayner and Suzanne E. Fenton --Biological impact of radiation exposure on breast cancer development /David H. Nguyen, Irineu Illa Bochaca, and Mary Helen Barcellos-Hoff --Brain estrogens and metabolism /Yong Xu and Deborah J. Clegg.
  • Part 1. General Principles -- Introduction / Deodutta Roy and M. Tevfik Dorak -- Gene-Environment Interactions, Phenotypic Changes, and Human Health / Rosemarie G. Ramos and Kenneth Olden -- Statistics for Testing Gene-Environment Interaction / Momiao Xiong and Xuesen Wu -- Clustering Studies for Identifying the Role of Environmental Factors in Aetiology of Human Cancers / Richard J.Q. McNally -- Discovering Gene-Gene and Gene-Environment Causal Interactions Using Bioinformatics Approaches / Changwon Yoo -- Gene Environment Interactions and Vascular Lesions / Quentin Felty -- Epigenetic Changes in Cancer: Role of Environment / Zdenko Herceg and Paolo Boffetta -- Approaches to Identify Environmental and Epigenomic Components or Covariates of Cancer and Disease Susceptibility / Alok Deoraj and Deodutta Roy -- Part 2. Environment and Specific Types of Cancer -- Gene-Environment Interaction and Susceptibility to Pediatric Brain Tumors / Brian Kunkle, David Sandberg, Prasanna Jayakar, Quentin Felty and Deodutta Roy -- Genetic Polymorphisms Predisposing Individuals to Breast Cancer Via Gene-Environment Interaction / Keun-Young Yoo, Sue K. Park and Aesun Shin -- Environment, Genetic Immunology and Childhood Cancer / Esma Ucisik-Akkaya and M. Tevfik Dorak -- Exposure to Environmental Mutagens: APC and Colorectal Carcinogenesis / Aruna S. Jaiswal, Melissa L. Armas, Shahnjayla K. Connors, Harekrushna Panda and Satya Narayan -- Gene-Environmental Interactions and Susceptibility to Liver Cancer / John B. Colerangle -- Genetic Epidemiology of Mismatch Repair Deficiency in Ovarian Cancer / Tuya Pal, Jenny Permuth Wey and Thomas A. Sellers -- Part 3. Case Studies -- Betel Nut and Susceptibility to Cancer / Rajesh N. Sharan and Yashmin Choudhury -- Birth Weight and Cancer Associations / Nadia Barahmani and M. Fatih Okcu -- Iron Excess and Cancer / Charronne F. Davis and M. Tevfik Dorak.
  • Epidermal cell tumors 2011, Springer
    Benign melanocytic proliferations -- Essential criteria for diagnosing melanoma -- Histologic mimics of malignant melanoma -- Epidermal neoplasms -- Pilosebaceous neoplasms -- Tumors with eccrine differentiation -- Merkel cell carcinoma.
  • The Normal Breast -- Specimen Processing -- Fibrocystic Change and Duct Ectasia -- Adenosis -- Intraductal Proliferative Lesions -- Intraductal Papillary Neoplasms -- Lobular Intraepithelial Neoplasia (LIN) -- Infiltrating Ductal Carcinoma (NOS Type) -- Invasive Lobular Carcinoma (ILC) -- Special Types of Breast Carcinomas -- Biphasic Tumors -- Disease of the Nipple -- Male Breast Lesions -- Mesenchymal Lesions/Tumors -- Myoepithelial Lesions/Neoplasms -- Miscellaneous Lesions -- Cytopathology of Benign and Malignant Lesions (Selected Topics) -- Immunohistochemistry (Selected Topics).
  • This book is updated with evidence from the latest published reviews and is more clinically focused, with an emphasis on application of the trial findings. With increased coverage of trials in the area of supportive care for pediatric cancer patients, each chapter opens with a clinical question and concludes with a summary on the trial findings from an expert commentator.
  • Historical Introduction --Descriptive Biostatistics --Inferential Biostatistics (I): Estimating Values of Biomedical Magnitudes --Inferential Biostatistics (II): Estimating Biomedical Behaviors --Equations: Formulating Biomedical Laws and Biomedical Magnitudes --Systems of Equations: The Explanation of Biomedical Phenomena (I). Basic Questions --Systems of Equations: The Explanation of Biomedical Phenomena (II). Dynamic Interdependencies --Optimal Control Theory: From Knowledge to Control (I). Basic Concepts --Optimal Control Theory: From Knowledge to Control (II). Biomedical Applications --Game Theory.
  • T cell therapy: state-of-the-art -- Extending the use of adoptive T cell immunotherapy for infections and cancer -- Non-T cell therapeutic approaches -- B lymphocytes in cancer immunology -- Monoclonal antibody therapy for cancer -- Natural killer cells for cancer immunotherapy -- Dendritic cell-based cancer vaccines: practical considerations -- Mesenchymal stromal cells: an emerging cell-based pharmaceutical -- T cell therapeutic approaches -- Tumor-specific mutations as targets for cancer immunotherapy -- Counteracting subversion of MHC class II antigen presentation by tumors -- Mechanisms and implications of immunodominance in CD8⁺ T-cell responses -- T regulatory cells and cancer immunotherapy -- Negative regulators in cancer immunology and immunotherapy -- Genetically engineered antigen specificity in T cells for adoptive immunotherapy -- Non-cellular aspects of cancer immunotherapy -- Cytokine immunotherapy -- Transcriptional modulation using histone deacetylase inhibitors for cancer immunotherapy -- Combining cancer vaccines with conventional therapies -- Combining oncolytic viruses with cancer immunotherapy -- Radiation therapy and cancer treatment: from the basics to combination therapies that ignite immunity -- Assessing immunotherapy through cellular and molecular imaging -- Transplantation -- Allogeneic and autologous transplantation therapy of cancer: converging themes.
  • Extranodal lymphomas 2011, ScienceDirect
    Introduction to extranodal lymphomas / Judith A. Ferry -- Lymphomas of the nervous system and the meninges / Judith A. Ferry -- Lymphomas of the head and neck / Judith A. Ferry -- Lymphomas of the thorax / Judith A. Ferry -- Lymphomas of the esophagus, gastrointestinal tract, hepatobiliary tract, and pancreas / Judith A. Ferry -- Lymphomas of the spleen / Aliyah R. Sohani and Lawrence R. Zukerberg -- Adrenal lymphomas / Judith A. Ferry -- Lymphomas of the urinary tract / Judith A. Ferry -- Lymphomas of the male genital tract / Judith A. Ferry -- Lymphomas of the female genital tract / Judith A. Ferry -- Cutaneous lymphomas / Lyn M. Duncan, Johanna l. Baran, and Judith A. Ferry -- Lymphomas of bone / Judith A. Ferry -- Lymphomas of the bone marrow / Robert P. Hasserjian -- Intravascular lymphomas / Judith A. Ferry.
  • FDG PET/CT has rapidly emerged as an invaluable combined imaging modality that can identify tumors on the basis of not only anatomical alterations but also metabolic activity, thus allowing the detection of lesions that would otherwise be too small to distinguish. This book, comprising a collection of images from oncology cases, is organized according to the role of FDG PET/CT in the evaluation and management of oncology patients, and only secondarily by organ or tumor entity. In this way, it reflects the issues that clinicians actually address in their daily practice, namely: identification of an unknown or unsuspected primary; determination of the extent of disease; evaluation of response to therapy; and surveillance after response, i.e., detection of recurrent disease. In total, 100 cases involving different primary tumors are presented to illustrate findings in these different circumstances. FDG PET/CT in Clinical Oncology will be of great value to all newcomers to this field, whether medical students, radiology, nuclear medicine, or oncology fellows, or practicing physicians.
  • This book provides a detailed update on all aspects of fine-needle aspiration cytology of breast lesions. It will serve readers as an up-to-date reference and atlas on both new entities in breast pathology, including borderline lesions such as flat epithelial atypia, and the classic benign and malignant lesions. Throughout, emphasis is placed on the characteristic diagnostic features as well as the common pitfalls faced by cytologists. As cytologic features can be highly variable, corresponding cytology and histology images are displayed together, enabling readers to gain a good understanding of the morphologic features of various lesions. Core-needle biopsy and fine-needle aspiration cytology are compared in depth, with attention to their relative strengths and weaknesses and indications. In addition, the impact of molecular classification of breast cancers on cytologic diagnosis is explored, and the use of molecular techniques in diagnostic cytology is discussed.
  • Historical aspects -- Techniques -- Flow cytometry in fine-needle aspiration diagnosis of lymphomas / in collaboration with Anna Porwit-MacDonald -- B cell neoplasms -- T cell neoplasms -- Hodgkin lymphoma -- Lymphadenopathy in HIV-infected patients -- Histiocytic and dendritic neoplasms -- Extranodal lymphomas -- Lymphoma look-alike.
  • History, indications, technique and limitations / Singh, A.D. ... [et al.] -- Cytological preparation / Brainard, J.A., Biscotti, C.V. -- Uveal metastases / Biscotti, C.V., Singh, A.D. -- Uveal lymphoma / Chute, D.J., Biscotti, C.V., Singh, A.D. -- Uveal melanoma : diagnostic features / Biscotti, C.V., Singh, A.D. -- Uveal melanoma : prognostication / Turell, M.E. ... [et al.] -- Vitreous biopsy : specimen preparation and interpretation / Coupland, S.E. -- Fine needle aspiration biopsy of retinal tumors / Ali, M.J. ... [et al.] -- Fine needle aspiration cytology in orbital tumors / Seregard, S., Tani, E. -- Future of ophthalmic fine needle aspiration biopsy / Singh, A.D., Dolan, B., Biscotti , C.V.
  • Fractal analysis is useful in digital image processing for the characterization of shape roughness and gray-scale texture or complexity. Breast masses present shape and gray-scale characteristics in mammograms that vary between benign masses and malignant tumors. This book demonstrates the use of fractal analysis to classify breast masses as benign masses or malignant tumors based on the irregularity exhibited in their contours and the gray-scale variability exhibited in their mammographic images. A few different approaches are described to estimate the fractal dimension (FD) of the contour of a mass, including the ruler method, box-counting method, and the power spectral analysis (PSA) method. Procedures are also described for the estimation of the FD of the gray-scale image of a mass using the blanket method and the PSA method.
  • Cancer survivors -- The medical and psychological concerns of cancer survivors after treatment -- Delivering cancer survivorship care -- Providers of survivorship care: their supply and education and training -- Employment, insurance, and economic issues -- Research.
  • The origin and development of neural crest-derived melanocytes / Debra L. Silver and William J. Pavan -- MITF : a matter of life and death for the developing melanocytes / Heinz Arnheiter ... [et al.] -- MITF : critical regulator of the melanocyte lineage / Erez Feige, Laura L. Poling, and David E. Fisher -- Melanocytes and the transcription factor Sox10 / Michael Wegner -- Human cutaneous pigmentation : a collaborative act in the skin, directed by paracrine, autocrine, and endocrine factors and the environment / Zalfa A. Abdel-Malek and Ana Luisa Kadekaro -- Melanocyte distribution and function in human skin : effects of ultraviolet radiation / Yuji Yamaguchi and Vincent J. Hearing --Altered signal transduction in melanoma / Pablo López Bergami, Anindita Bhoumik, and Ze'ev Ronai -- BRN2 in melanocytic cell development, differentiation, and transformation / Anthony L. Cook ... [et al.] -- The dynamic roles of cell-surface receptors in melanoma development / Dong Fang and Meenhard Herlyn -- Familial melanoma genes, melanocyte immortalization, and melanoma initiation / Dorothy C. Bennett -- Genetic progression from melanocyte to malignant melanoma / Boris C. Bastian -- The multiple roles of the oncogenic protein SKI in human malignant melanoma / Dahu Chen ... [et al.] -- RB/E2F regulation and dual activity in the melanocytic system / Ruth Halaban -- Melanoma development and pigment cell transformation / Claudia Wellbrock -- The biology and genetics of melanoma / Norman E. Sharpless and Lynda Chin -- The biology of xeroderma pigmentosum : insights into the role of ultraviolet light in the development of melanoma / James E. Cleaver -- Divergent pathways to cutaneous melanoma / David C. Whiteman and Adéle C. Green -- Pigmentation, DNA repair, and candidate genes : the risk of cutaneous malignant melanoma in a mediterranean population / Maria Teresa Landi -- Low-penetrance genotypes, pigmentation phenotypes, and melanoma etiology / Peter A. Kanetsky and Timothy R. Rebbeck -- The biology of melanoma progression : from melanocyte to metastatic seeds / A. Neil Crowson, Cynthia Magro, and Martin C. Mihm, Jr. -- Optical imaging analysis of atypical nevi and melanoma / Amanda Pfaff Smith and Dorothea Becker -- Proteomics analysis of melanoma cell lines and cultured melanocytes / Katheryn A. Resing and Natalie G. Ahn --Paradigm of metastasis for malignant melanoma / Stanley P.L. Leong -- Repair of UV-induced DNA damage and melanoma risk / Qingyi Wei -- High risk factors for melanoma metastasis / Neil A. Accortt and Seng-jaw Soong -- Role of melanoma inhibitory activity in early development of malignant melanoma / Anja-Katrin Bosserhoff -- Role and regulation of PAR-1 in melanoma progression / Carmen Tellez and Menashe Bar-Eli -- Molecular mechanisms of melanoma metastasis / Mohammed Kashani-Sabet -- Overview of tumor progression in melanoma / David E. Elder -- The plasticity of melanoma cells and associated clinical implications / Mary J. C. Hendrix ... [et al.] -- The clinical use of molecular markers as predictors of disease outcome and response to therapy in malignant melanoma / Steve R. Martinez, Hiroya Takeuchi, Dave S.B. Hoon -- The role of DCT/TYRP2 in resistance of melanoma cells to drugs and radiation / Brian J. Pak and Yaacov Ben-David -- How melanoma cells evade chemotherapy : role of transporter-dependent and -independent resistance mechanisms / Kevin G. Chen and Michael M. Gottesman -- Apoptosis in melanoma: approaches to therapy / Heicke Röckmann and Dirk Schadendorf -- Role of melanoma-associated antigens / Rishab K. Gupta, Ana M. McElrath-Garza, and Donald L. Morton -- Host responses to melanoma : implications for immunotherapy / Julian A. Kim and Ernest Borden -- Future perspectives / Vincent J. Hearing and Stanley P.L. Leong.
  • "The traditional problem of the poor presentability as well as diagnostic and therapeutic practicability of individual patient care is still unresolved. The present book aims at leading the reader (cancer researchers, pharmacologists, biologists) away-in a scientifically accessible manner-from the daily conflicts between theory and practice and between the generalized and individual tumor patient, so that more personalized diagnostic and therapeutic strategies can be developed for controlling metastatic tumor disease: First, recording the systems concept of tumor biology based on rather different sciences (biochemistry, cell biology, and medical oncology) including their potential contribution to communication, then, giving reductionistically derived systems features an internal communicative context (formal-pragmatic communication theory), and finally, binding the systems features to (tumor-immanent) evolutionary processes (modularity of biochemical and cellular processes, rationalization of biologic functions)"--Back cover.
  • Intraoperative evaluation of colorectal specimens containing cancer -- Intraoperative evaluation for extracolonic disease in colon cancer patients -- Metastases and mimics of colorectal carcinoma -- Non-epithelial tumors of the colorectum -- Frozen section assessment of the colorectum in the pediatric population -- Frozen section evaluation of the appendix -- Frozen section evaluation of anal disease.
  • 1. Sentinel Lymph Nodes -- 2. Assessment of the Surgical Margins -- 3. Diagnostic Evaluation of a Breast Mass -- 4. Handling of Specimens with a Nonpalpable Lesion -- 5. Core Needle Biopsies -- 6. Regulatory Requirements for Breast Specimens.
  • Ch. 1. Introduction -- Ch. 2. Potential to reduce the cancer burden through cancer prevention and early detection -- Ch. 3. Lifestyle behaviors contributing to the burden of cancer -- Ch. 4. Modifying health risk behaviors -- Ch. 5. Potential of screening to reduce the burden of cancer -- Ch. 6. Improving participation in cancer screening programs -- Ch. 7. Adopting new technology in the face of uncertain science: the case of screening for lung cancer -- Ch. 8. Professional education and training -- Ch. 9. Federal programs that support cancer prevention and early detection -- Ch. 10. Research trends and opportunities -- Ch. 11. Findings, policy implications, and recommendations.
  • Introduction of cancer prevention -- Assessing human and economic benefits of cancer prevention -- The role of diet, physical activity and body composition in cancer prevention -- Hereditary risk for cancer -- Human categories and health: the power of the concept of ethnicity -- Complementary and alternative approaches to cancer prevention -- The drug development process -- Developing topical prodrugs for skin cancer prevention -- Skin cancer prevention -- Colorectal cancer prevention -- Lung cancer prevention -- Breast cancer prevention -- Prostate cancer prevention -- Cervical and endometrial cancer prevention -- Ovarian cancer prevention -- Cancer survivorship.
  • Gamma knife neurosurgery 2011, Springer
  • Gastrointestinal cancer 2005, Springer
  • Gene therapy for cancer 2007, Springer
    Adenovector-mediated cancer gene therapy /Bingliang Fang and Jack A. Roth --Efficacy, toxicity, and immunogenicity of adenoviral vectors /Dmitry M. Shayakhmetov --Lentiviral and retroviral vector systems /Renata Stripecke and Noriyuki Kasahara --Vaccinia and pox-virus /Sricharan Chalikonda and David L. Bartlett --Herpes simplex virus as a therapy for cancer /Ian J. Mohr --Alphavirus vectors for gene therapy applications /Kenneth Lundstrom --Vesicular stomatitis virus and RNA viruses as gene therapy vectors /Glen N. Barber --Parvovirus vectors /Selvarangan Ponnazhagan --Nonviral vector systems /Pui-yan Lee and Leaf Huang --Oncogenes, tumor suppressor genes, and apoptosis-inducing genes utilized in cancer gene therapy /Lidong Zhang and Bingliang Fang --Gene silencing therapy against cancer /Chao-Zhong Song --Tumor targeting-retargeted adenovirus /Masato Yamamoto and David T. Curiel --Oncolytic herpes simplex for gene therapy in preclinical and clinical trials /Richard H. Pin ... [et al.] --Cytokine gene therapy for genitourinary cancer /Terry L. Timme ... [et al.] --Combination of gene therapy with radiation /Anupama Munshi and Raymond E. Meyn --Gene transfer for chemoprotection and enrichment of hematopoietic stem cells /Justin C. Roth and Stanton L. Gerson --Nonviral genetic vaccines for cancer /Steven R. Little, Daniel G. Anderson, and Robert Langer --Gene therapy targeted at angiogenesis and lymphangiogenesis for cancer treatment /Anita T. Tandle and Steven K. Libutti --Tumor-specific replicating adenoviruses : delta 24 for human gliomas /Giacomo G. Vecil, Juan Fueyo, and Frederick F. Lang --Problems, side effects, and disappointments in clinical cancer gene therapy /Ta-Chiang Liu and David H. Kirn --Trials and tribulations in developing clinical trials of gene therapy : E1A for breast or ovarian cancer /Naoto T. Ueno ... [et al.] --Phase I clinical experience with intravenous administration of PV701, an oncolytic virus /Andrew L. Pecora and Robert M. Lorence --MDA-7/IL-24 as a multi-modality therapy for cancer /Sunil Chada ... [et al.] --Development of therapeutic genes for breast cancer treatment /Mien-Chie Hung and Duen-Hwa Yan --Steps in a translational cancer gene therapy trial /Urs W. von Holzen and Stephen G. Swisher.
  • General principles of tumor immunology -- A perspective on cancer immunology and immunotherapy -- Tumor antigens -- T cells and antigen recognition -- The role of natural killer T cells in tumor immunity -- Immunomodulatory molecules of the immune system -- HLA class I antigen abnormalities in tumors -- The local tumor microenvironment -- Tumor vaccines -- Peptide and protein vaccines for cancer -- DNA vaccines against cancer -- Recombinant viral and bacterial vaccines -- Dendritic cell vaccines -- Whole cell vaccines -- Carbohydrate vaccines against cancer -- Passive immunotherapy approaches -- Monoclonal antibody therapy of cancer -- Adoptive cellular therapy for the treatment of cancer -- Checkpoint blockade and combinatorial immunotherapies -- Clinical tumor immunotherapy -- General approaches to measuring immune responses -- Interferon therapy -- High dose interleuken-2 therapy -- Monoclonal antibodies in cancer therapy -- Unmasking tumor cell immunogenicity by chemotherapy: implications for therapy.
  • Genetic recombination in cancer 2003, ScienceDirect
  • Genetics for surgeons 2005, NCBI Bookshelf
  • Genomic experimental approaches in oncology -- Pharmacogenomics of toxicity and response of chemotherapy -- Pharmacogenomics in clinical drug development in oncology.
  • Geocoding health data 2008, CRCnetBASE
  • Geriatric oncology 2009, Springer
    Aging and cancer, what oncologists need to know / Arti Hurria, Lodovico Balducci -- Assessing the older cancer patient / Melissa Cohen, David Reuben, Arash Naeim -- Cancer screening in older adults / Louise C. Walter -- Physiological consequences of aging / Bindu Kanapuru, William B. Ershler -- Assessment and impact of comorbidity in older adults with cancer / Athanasios Karampeasiz, Martine Extermann -- Geriatric syndromes defined and explained for oncology practice / Miriam B. Rodin -- Family caregivers / Betty R. Ferrell, Polly Mazanec -- Surgical management of the older patient with cancer / David M. Heimann, M. Margaret Kemeny -- Chemotherapy for the older adult with cancer / Supriya Mohile, Nail Nagovskiy, Lodovico Balducci -- Radiation therapy in geriatric oncology / Sarah E. Hoffe, Mark S. Russell -- Palliative care, special considerations for older adults with cancer / Genevieve N. Thompson, Harvey M. Chochinov.
  • Glioblastoma 2010, Springer
  • Glioma 2012, Springer
    Molecular biology of glioma / Tomotoshi Marumoto and Hideyuki Saya -- Recent surgical management of gliomas / Nader Sanai and Mitchel S. Berger -- Recent medical management of glioblastoma / Derek R. Johnson and Susan M. Chang -- Basic concepts in glioma immunology / Ian F. Parney -- Mechanisms of immune evasion by gliomas / Cleo E. Rolle, Sadhak Sengupta, and Maciej S. Lesniak -- Glioma antigen / Masahiro Toda -- Cytokine therapy / Masasuke Ohno, Atsushi Natsume, and Toshihiko Wakabayashi -- Immunotherapeutic approach with oligodeoxynucleotides containing CpG motifs (CpG ODN) in malignant glioma / Renata Ursu and Antoine F. Carpentier -- Adoptive cell transfer therapy for malignant gliomas / Eiichi Ishikawa ... [et al.] -- Monoclonal antibody therapy for malignant glioma / Kevin S. Chen and Duane A. Mitchell -- Animal models for vaccine therapy / Dong-Sup Chung, Chang-Hyun Kim, and Yong-Kil Hong -- Immunogene therapy / Terry Lichtor and Roberta P. Glick -- Peptide vaccine / Shuichi Izumoto -- Active immunotherapy : oncolytic virus therapy using HSV-1 / Tomoki Todo -- Dendritic cell vaccines / Ryuya Yamanaka and Koji Kajiwara -- Antigen-receptor gene-modified T cells for treatment of glioma / Hiroaki Ikeda and Hiroshi Shiku -- Glioma stem cell research for the development of immunotherapy / Qijin Xu, Xiangpeng Yuan, and John S. Yu.
  • Glioma signaling 2013, Springer
  • Gliomas 2009, Springer
    Part I. Gliomas -- Astrocytic tumors / Markus J. Riemenschneider and Guido Reifenberger -- Molecular pathology of oligodendroglial tumors / Christian Hartmann and Andreas von Deimling -- Ependymal tumors / Martin Hasselblatt -- Pediatric gliomas / Stefan Pfister and Olaf Witt -- Hereditary tumor syndromes and gliomas / David Reuss and Andreas von Deimling -- Part II. Management of gliomas -- Surgical management of intracranial gliomas / Matthias Simon and Johannes Schramm -- Radiation therapy / Stephanie E. Combs -- Adjuvant therapy / Wolfgang Wick and Michael Weller -- Other experimental therapies for glioma / Manfred Westphal and Katrin Lamszus -- Neurotoxicity of treatment / Pasquale Calabrese and Uwe Schlegel -- Neuroimaging / R. Klingebiel and G. Bohner -- Part III. Angiogenesis in gliomas / Marcia Machein and Lourdes Sánchez de Miguel -- Gene regulation by methylation / Wolf C. Mueller and Andreas von Deimling -- Brain tumor stem cells / Christian Nern, Daniel Sommerlad, Till Acker and Karl H. Plate.
  • Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes. Aids the development of therapeutic treatments for cancer. Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research.
  • Regulation of tumor initiation and metastatic progression by eph receptor tyrosine kinases / Jin Chen -- Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis / Ombretta Salvucci, Giovanna Tosato -- Semaphorin signals tweaking the tumor microenvironment / Claudia Muratori, Luca Tamagnone -- Guidance for life, cell death, and colorectal neoplasia by netrin dependence receptors / Christian Gespach -- Roundabout way to cancer / Mimmi S. Ballard, Lindsay Hinck -- Role of the VEGF/VEGFR axis in cancer biology and therapy.
  • This study (EGF104911) is designed to evaluate the efficacy and safety of lapatinib in patients with advanced or metastatic breast cancer. Eligible subjects must have ErbB2 overexpressing tumors and are refractory to treatment with anthracycline, taxanes and trastuzumab containing regimens. The study data obtained from EGF104911 will be combined with the data from EGF100642 and integrated analysis will be carried out in order to enhance the credibility of the study results.
  • Gynecologic cancer 2006, Springer
    Multidisciplinary care of patients with gynecologic cancers / David M. Gershenson ... [et al.] -- Prevention and early detection of endometrial and ovarian cancers / Karen H. Lu -- Preinvasive disease of the lower genital tract / Andrea Milbourne -- Selected topics in gynecologic pathology / Anais Malpica, Michael T. Deavers, and Elvio G. Silva -- Imaging of gynecologic malignancies / Revathy Iyer -- Contemporary treatment of vaginal and vulvar cancers / Patricia J. Eifel and Thomas W. Burke -- Treatment of early cervical cancer / Charles F. Levenback -- Treatment of locally advanced cervical cancer / Anuja Jhingran, Patricia J. Eifel, and Pedro T. Ramirez -- Uterine sarcomas / Lois M. Ramondetta ... [et al.] -- Treatment of endometrial cancer / Lois M. Ramondetta ... [et al.] -- Surgery for ovarian cancer / Judith K. Wolf and J. Taylor Wharton -- Chemotherapy for epithelial ovarian cancer / Michele L. Donato ... [et al.] -- Treatment of rare ovarian malignancies / Jubilee Brown and David M. Gershenson -- Gestational trophoblastic disease / Hui T. See ... [et al.] -- Fertility-sparing options for treatment of women with gynecologic cancers / Pedro T. Ramirez -- Quality of life and sexual functioning / Diane C. Bodurka and Charlotte C. Sun -- Palliative care for gynecologic malignancies / Florian Strasser, Michael W. Bevers, and Eduardo Bruera.
  • Gynecological imaging 2013, Springer
    This book provides a detailed guide to the use and interpretation of color Doppler ultrasound, CT, and MR imaging in patients with gynecological disorders. The advantages and limitations of each modality in imaging different pathologies are clearly presented, and advice is provided on the most appropriate option when ultrasound does not permit a definite diagnosis or fails to determine the precise extension of a lesion. Throughout, emphasis is placed on the importance of microscopic and macroscopic findings for a full understanding of the radiological appearances, and relevant points from the basic sciences are also highlighted. Special attention is paid to issues of differential diagnosis and imaging results that are characteristic of a particular type of lesion. The authors are recognized experts in the field who draw upon their considerable experience to provide an up-to-date reference book highly relevant to everyday clinical practice.
  • Biologic and pharmacologic basis of cancer chemotherapy and biotherapy / Roland T. Skeel and Samir N. Khleif -- Systemic assessment of the patient with cancer and long-term consequences of treatment / Roland T. Skeel -- Selection of treatment for the patient with cancer / Roland T. Skeel -- Antineoplastic drugs and biologic response modifiers : classification, use, and toxicity of clinically useful agents / Roland T. Skeel -- High-dose chemotherapy and hematopoietic stem cell transplantation in hematologic malignancies / Roberto Rodriguez and Chatchada Karanes -- Carcinomas of the head and neck / Harlan A. Pinto -- Carcinoma of the lung / Sophie Sun and Joan H. Schiller -- Carcinomas of the gastrointestinal tract / Al B. Benson, III -- Carcinomas of the pancreas, liver, gallbladder, and bile ducts / Rekha T. Chaudhary -- Carcinoma of the breast / Iman Mohamed -- Gynecologic cancer / Stephen Andrews -- Urologic and male genital cancers / Joseph S. Chan, Scott B. Saxman, and Craig R. Nichols -- Kidney cancer / Walter D. Y. Quan, Jr. and Mikhail Vinogradov -- Thyroid and adrenal carcinomas / Haitham S. Abu-Lebdeh and Samir N. Khleif -- Melanomas and other skin malignancies / Karen S. Milligan and Walter D. Y. Quan, Jr. -- Primary and metastatic brain tumors / April F. Eichler and Tracy T. Batchelor -- Soft tissue sarcomas / Robert S. Benjamin --Bone sarcomas / Robert S. Benjamin -- Acute leukemias / Olga Frankfurt and Martin S. Tallman -- Chronic leukemias / Peter White and Paul R. Walker -- Myeloproliferative diseases and myelodysplastic syndromes / Peter White and Paul R. Walker -- Hodgkin's lymphoma / Richard S. Stein and David S. Morgan -- Non-Hodgkin's lymphoma / Richard S. Stein and John P. Greer -- Multiple myeloma, other plasma cell disorders , and primary amyloidosis / Rachid Baz and Mohamad A. Hussein -- Metastatic cancer of unknown origin / James M. Leonardo -- Human immunodeficiency virus / Mary E. Cianfrocca -- Side effects of cancer chemotherapy / Janelle M. Tipton -- Infections : etiology, treatment, and prevention / Joan M. Duggan -- Transfusion therapy, bleeding, and clotting / Mary R. Smith and NurJehan Quraishy -- Oncology emergencies and critical care issues, anaphylaxis, spinal cord compression, cerebral edema, superior vena cava syndrome, hypercalcemia, tumor lysis syndrome, and respiratory failure / Roland T. Skeel -- Malignant pleural, peritoneal, and pericardial effusions and meningeal infiltrates / Rekha T. Chaudhary -- Cancer pain / Michael J. Fisch and Charles S. Cleeland -- Emotional and psychiatric problems in patients with cancer / Kathleen S. N. Franco-Bronson and Kristi S. Williams.
  • SECTION I: BASIC PRINCIPLES AND CONSIDERATIONS OF RATIONAL CHEMOTHERAPY AND MOLECULAR THERAPY -- 1. Biologic and pharmacologic basis of cancer chemotherapy / Roland T. Skeel -- 2. Biologic basis of molecular targeted therapy / Osama E. Rahma, Samir N. Khleif -- 3. Systemic assessment of the patient with cancer and consequences of treatment / Roland T. Skeel -- 4. Selection of treatment with the patient with cancer / Roland T. Skeel -- SECTION II: CHEMOTHERAPY AND MOLECULAR THERAPY OF HUMAN CANCER -- 5. Carcinonas of the head and neck / Barbara A. Murphy -- 6. Carcinomas of the lung / David E. Gerber, Joan H. Schiller -- 7. Carcinomas of the gastrointestinal tract / Maxwell Vergo, AI B. Benson III -- 8. Carcinomas of the pancreas, liver, gallbladder, and bile ducts / Timothy J. Kennedy, Steven K. Libutti -- 9. Carcinomas of the breast / Patrick Glyn Morris, Clifford A. Hudis -- 10. Gynecologic cancer / Thomas McNally, Richard T. Penson, Chau Tran, Michael J. Birrer -- 11. Urologic and male genital cancers / Brendan D. Curti, Craig R. Nichols -- 12. Kidney cancer / Mark T. Andolina, Colleen Darnell, Olivier Rixe -- 13. Thyroid and adrenal cancinomas / Haitham S. Abu-Lebdeh, Michael E. Menefee, Keith C. Bible -- 14. Melanomas and other cutaneous malignancies / Ragini Kudchadkar, Jeffrey S. Weber -- 15. Primary and metastatic brain tumors / April Fitzsimmons Eichler, Tracy T. Batchelor -- 16. Soft tissue sarcomas / Robert S. Benjamin -- 17. Bone sarcomas / Robert S. Benjamin -- 18. Acute leukemias / Olga Frankfurt, Martin S. Tallman -- 19. Chronic leukemias / Khaled el-Shami, Bruce D. Cheson -- 20. Myeloproliferative neoplasms and myledysplastic syndromes / Elias Jabbour, Hagop Kantarjian -- 21. Hodgkin lymphoma / Richard S. Stein, David S. Morgan -- 22. Non-Hodgkin lymphoma / Mark Roschewski, Wyndham H. Wilson -- 23. Multiple myeloma, other plasma cell disorders, and primary amyloidosis / Rachid Baz, Mohamad A. Hussein -- 24. Metastatic cancer of unknown origin / James M. Leonardo -- 25. HIV-associated malignancies / Thomas S. Uldrick, Mark N. Polizzotto, Robert Yarchoan -- SECTION III: SUPPORTIVE CARE OF PATIENTS WITH CANCER -- 26. Side effects of chemotherapy and molecular targeted therapy / Janelle M. Tipton -- 27. Infections: etiology, treatment, and prevention / Thomas J. Walsh, Joan M. Duggan -- 28. Transfusion therapy, bleeding, and clotting / Mary R. Smith, NurJehan Quraishy -- 29. Oncology emergencies and critical care issues: spinal cord compression, cerebral edema, Superior Vena Cava Syndrome, anaphylaxis, respiratory failure, Tumor Lysis Syndrome, hypercalcemia, and bone metastasis / Roland T. Skeel -- 30. Malignant pleural, peritoneal, and pericardial effusions and meningeal infiltrates / Rekha T. Chaudhary -- 31. Cancer pain / Richard T. Lee, Michael J. Fisch -- 32. Emotional and psychiatric problems in patients with cancer / Kristi Skeel Williams, Kathleen S.N. Franco-Bronson -- SECTION IV: CHEMOTHERAPEUTIC AND MOLECULAR TARGETED AGENTS AND THEIR USE -- 33. Classification, use, and toxicity of clinically useful chemocherapy and molecular targeted therapy / Roland T. Skeel -- Appendix A: Nomogram for determining body surface area of adults from height and mass -- Appendix B: Nomogram for determining boy surface area of children from height and mass.
  • Part I: --Burden --Cancer survivorship: a bird's eye view from an insider /Michael Feuerstein --The burden of cancer survivorship: a pandemic of treatment success /Steven N. Wolff --Quality of care /Craig C. Earle --Quality of life in long-term cancer survivors /Joan Bloom, Soo H. Kang, Dana M. Petersen, and Susan L. Stewart --Health care disparities /Salewa Oseni and Ismail Jatoi --Measuring quality of life in cancer survivors /David Victorson, David Cella, Lynne Wagner, Laura Kramer, and Mary Lou Smith --Part II: --Common problems --Exercise motivation and behavior change /Kerry S. Corneya, Kristina H. Karvinen, and Jeffrey K.H. Vallance --Fatigue /Alexander V. Ng, Carlynn A. Alt, and Elizabeth M. Gore --Pain /Victor T. Chang and Ryuichi Sekine --Depression /Peter C. Trask and Timothy Pearman --Interpersonal relationships /Andrea A. Thorton and Martin A. Perez --Adaptation in the face of advanced cancer /Carissa A. Low, Tammy Beran, and Annette L. Stanton --Part III: --Secondary prevention --Restoring emotional well-being: a model /Robert W. Lent --Physical activity for cancer survivors: potential benefits and guidelines /Clare Stevinson, Kristin L. Campbell, Christopher M. Sellar, and Kerry S. Courneya --Nutrition and weight management in cancer survivors /Virginia Uhley and K. L. Catherine Jen --Management of chemotherapy related cognitive dysfunction /Robert J. Ferguson, Raine Riggs, Tim Ahles, and Andrew J. Saykin --Smoking cessation and cancer survivors /Jamie S. Ostroff and Lara K. Dhingra --Psychological distress, depression, and anxiety /Arthur M. Nezu and Christine Maguth Nezu --Managing daily and long-term stress /Linda E. Carlson and Michael Speca --Pain and function: a psychosocial perspective /Michael J.L. Sullivan, Pascal Thibault, Andre Savard, and Ana Velly --Work /Jos Vebeek and Evelien Spelten --Comprehensive long-term follow-up: cancer survivorship centers /Linda A. Jacobs, Jane Alavi, Angela DeMichele, Steven Palmer, Carrie Stricher, and David Vaughn --Part IV: --Survivor and provider perspectives --Survivor perspectives on quality care /Kathryn McPherson and Rod MacLeod --Living with advanced cancer /Sheila Payne --Part V: --International perspective --Global considerations /Patricia A. Findley --Part VI: --Future directions --Cancer survivorship: research, practice, and policy /Michael Feuerstein.
  • Skin cancer -- Central nervous system -- Malignant and benign diseases of the eye and orbit -- Cancer of the ear -- Nasopharyngeal cancer -- Nasal cavity and paranasal sinus cancer -- Oropharyngeal cancer -- Cancer of the lip and oral cavity -- Larynx and hypopharynx cancer -- Salivary gland tumors -- Thyroid cancer -- Unusual neoplasms of the head and neck -- Management of the neck and unknown primary of the head and neck -- Small cell lung cancer -- Non-small cell lung cancer -- Mesothelioma and thymic tumors -- Breast cancer -- Esophageal cancer -- Gastric cancer -- Pancreatic cancer -- Hepatobiliary cancer -- Colorectal cancer -- Anal cancer -- Renal call carcinoma -- Bladder cancer -- Prostate cancer -- Cancer of the penis -- Testicular cancer -- Cervical cancer -- Endometrial cancer -- Ovarian cancer -- Vaginal cancer -- Vulvar cancer -- Urethral cancer -- Hodgkin's lymphoma -- Non-Hodgkin's lymphoma -- Cutaneous lymphomas -- Multiple myeloma and plasmacytoma -- Bone tumors -- Soft-tissue sarcoma -- Pediatric (Non-CNS) tumors -- Palliation and benign conditions -- Clinical radiobiology and physics.
  • v. 1. Molecular genetics; Lung and breast carcinomas -- v. 2. Molecular pathology; Colorectal carcinoma and prostate carcinoma -- v. 3. Molecular genetics; Liver carcinoma and pancreatic carcinoma -- v. 4. Molecular genetics; Gastrointestinal carcinoma and ovarian carcinoma.
  • 1. Overview : therapeutic biomarkers in cancer / Sherry X. Yang and Janet E. Dancey -- 2. Statistical considerations in the development and evaluation of therapeutic biomarkers in cancer / Lisa M. McShane, Edward L. Korn, and Boris Freidlin -- 3. Role of biomarkers in clinical development of cancer therapies / Helen X. Chen -- 4. HER-2 as a prognostic and predictive biomarker in cancer / Suparna B. Wedam and Stanley Lipkowitz -- 5. Hormone receptors and endocrine therapy in breast cancer / Sherry X. Yang -- 6. Predictive biomarkers for epidermal growth factor receptor agents in non-small cell lung cancer / John Hilton, Penelope A. Bradbury, and Janet Dancey -- 7. Markers of sensitivity and resistance to EGFR inhibitors in colorectal cancer / Jose G. Monzon and Janet Dancey -- 8. Targeting BCR-ABL for molecular therapy of chronic myelogenous leukemia / Shamudheen Rafiyath, Guoqing Wei, and Delong Liu -- 9. Gastrointestinal stromal tumors : from molecular pathogenesis to therapy / Joaquina Baranda, Rashna Madan, and Andrew K. Godwin -- 10. PML/RARa fusion gene and response to retinoic acid and arsenic trioxide treatment / Alicja M. Gruszka and Myriam Alcalay -- 11. Dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity -- 12. UGT1A1 polymorphisms and mutations lead to irinotecan-induced toxicity / K.M. Reece and W.D. Figg -- 13. The 21-gene recurrence score and benefit of chemotherapy in estrogen receptor-positive breast cancer / Petra Rietschel and Joseph A. Sparano -- 14. Mammaprint for individualized recurrence risk assessment and treatment recommendations for early-stage breast cancer patients / Sonal J. Desai and Tianhong Li -- 15. BRCA mutation and PARP inhibitors / Marcie K. Weil ... [et al.] -- 16. EML4-ALK fusion gene and therapy with ALK-targeted agents in non-small cell lung cancer / Vimal Patel and Biren Saraiya -- 17. BRAF-targeted therapy in metastatic melanoma / Noori Kim and April Deng.
  • Head and neck cancer 2011, Springer
    Epidemiology and Aetiology of Head and Neck Cancers -- Head and Neck Cancer Prevention -- Cellular and Molecular Pathology of Head and Neck Tumors -- Oncogenomics/Proteomics of Head and Neck Cancers -- Genetics and Epigenetics of Head and Neck Cancer -- Immunology of Head and Neck Cancer -- HPV and EBV in Head and Neck Cancer -- Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCC -- Biomarkers in Head and Neck Cancer -- Hypoxia in Head and Neck Cancers: Clinical Relevance and Treatment -- Translational Research in Head and Neck Oncology -- Preclinical Models of Head and Neck Squamous Cell Carcinoma -- Morphologic Investigations in Head and Neck Cancer -- Ultrasound Investigations in Head and Neck Cancer Patients -- Functional Imaging -- Sentinel Node Biopsy for Head and Neck Cancer -- Approaches to Supportive Care -- Intensity-Modulated Radiation Therapy for Head and Neck Cancer -- Principles of Systemic Chemotherapy for Squamous Cell Head and Neck Cancer -- Molecular Targeted Therapies in Head and Neck Cancer -- Phase I Study Methodology in Head and Neck Oncology -- Evidence-Based Head and Neck Oncology: Principles and Pitfalls -- Programs of Organ and Function Preservation -- Multidisciplinary Approach of Unresectable Head and Neck Cancer -- Laser Endoscopic Treatment -- Multidisciplinary Management of Skull Base and Superstructure Tumors.Multidisciplinary Management of Oral Cavity and Maxillary Sinus Cancers -- Cancers of the Larynx: Tis, T1, T2 Evaluation and Management -- Multidisciplinary Management of Oropharynx Carcinomas -- Multidisciplinary Management of Hypopharyngeal Carcinoma -- Cancers of the Larynx: Tis, T1, T2 Evaluation and Management -- Diagnosis and Multidisciplinary Treatment of Laryngeal Cancers -- Principles and New Approaches in Surgical Reconstruction -- Multidisciplinary Treatment of the Neck -- Postoperative Management of High-Risk Resectable Head and Neck Cancer -- Management of Salivary Gland Cancer -- Head and Neck Melanoma -- Cervical Lymph Node Metastases of Squamous Cell Carcinoma from an Unknown Primary Site -- Management of Thyroid and Parathyroid Cancers -- Head and Neck Paragangliomas --Treatment of the Elderly Head and Neck Cancer Patient -- Interstitial Radiation Therapy in Cancer of the Oropharynx and Oral Cavity -- Proton Beam Therapy for Head and Neck Cancer -- Normal Tissue Complications and Protection in Head and Neck Cancer Patients -- Rehabilitation of Heavily Treated Head and Neck Cancer Patients -- Salvage Therapy in Head and Neck Cancer Patients -- Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck -- Best Supportive Care for Palliative Treatment -- Quality of Life in Head and Neck Cancer Patients -- Quality Assurance of Clinical Trials in the Management of Cancer in the Head and Neck.
  • Head and neck cancer 2003, ScienceDirect
  • General principles of management of head and neck cancer --General principles of head and neck pathology /Bruce M. Wenig and Jean-Marc Cohen --Prognostic factors in patients with head and neck cancer /Benjamin D. Smith and Bruce G. Haffty --General clinical evaluation of the head and neck patient /Douglas K. Frank and Roy B. Sessions --Special radiologic imaging considerations in the evaluation of squamous cell cancer of the head and neck /Suresh K. Mukherji --Novel radiation therapy techniques in the management of head and neck cancer /Avraham Eisbruch --Dental oncology and maxillofacial prosthetics /Jack W. Martin, James C. Lemon, and Mark C. Chambers --Total supportive care: nutrition, symptom management, pain, and psychosocial support /Elise Carper, Stewart B. Fleishman, and David Seres --General principles of rehabilitation of speech, voice, and swallowing function after treatment of head and neck cancer /Jan S. Lewin and Katherine A. Hutcheson --Site-specific principles of management of head and neck cancer --Management of the Neck-Surgery --Management of the neck: radiation therapy and chemotherapy /Kenneth S. Hu, Harry Quon, and Louis B. Harrison --Metastatic cancer to the neck from an unknown primary site --Cancer of the oral cavity --Cancer of the oropharynx --Early-stage cancer of the larynx --Advanced stage cancer of the larynx --Cancer of the hypopharynx and cervical esophagus --Cancer of the nasal vestibule, nasal cavity, and paranasal sinus: surgical management /Mark S. Persky and Abtin Tabaee --Cancer of the nasal cavity and paranasal sinus: radiation therapy and chemotherapy management --Cancer of the nasopharynx --Basal and squamous cell skin cancers --Melanoma of the head and neck --Malignant salivary gland tumors --Cancers involving the skull base and temporal bone /Ivo P. Janecka, et. al. --Pargangliomas of the head and neck --Cancer of the thyroid and parathyroid --Soft tissue and bone sarcomas of the head and neck --Cancer of the orbit: surgical management --Cancer of the orbit and ocular structures: radiation therapy and management /Jorge E. Freire, et.al. --Systemic targeted therapy for recurrent and metastatic head and neck cancer /Syed M. Ahmed, Victoria Villaflor, and Ezra E. W. Cohen --Basic science and epidemiology of head and neck cancer --Molecular biology of head and neck cancer /Patrick K. Ha, Joseph A. Califano, and David Sidransky --Molecular and genetic predisposition for the squamous cell carcinoma of the head and neck /Qingyi Wei, Kathryn L. Patterson, Erich M. Sturgis, and Margaret R. Spitz --Angiogenesis and metastases in head and neck cancer /Chad E. Galer and Jeffrey N. Myers --Human papillomavirus and prevention and therapy of head and neck cancer /Maura L. Gillison --Chemoprevention of head and neck cancer /Anne Tsao and Vassiliki A. Papadimitrakopoulou.
  • "Part of the popular Foundations in Diagnostic Pathology Series, Head and Neck Pathology delivers vital diagnostic guidance in a compact, high-yield format. Concise and easy to use, this pathology reference offers a practical, well-organized approach to evaluating a wide range of specimens in both head and neck and related endocrine pathology. Easily review normal histology before examining abnormal findings so you can avoid false positives. Reach accurate diagnostic conclusions easily with a consistent, user-friendly format that explores each entity's clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnoses, and prognostic and therapeutic considerations. Apply the latest diagnostic criteria for all of the most commonly seen neoplastic and non-neoplastic conditions of the larynx, hypopharynx, and trachea; nasal cavity, paranasal sinuses, and nasopharynx; oral cavity and oropharynx; salivary glands; ear; and temporal bone. Gain a superb visual understanding of important histologic features with hundreds of full-color illustrations representing a wide variety of pathologic lesions. Quickly reference key information with convenient, at-a-glance clinical and pathologic boxes throughout."--Summary of the editor.
  • Specific Challenges in Optimizing Health Care for Cancer Survivors -- What Is Quality Health Care for Cancer Survivors? -- Managing Symptoms over Time -- Health Behaviors and Wellness -- Rehabilitation in the Context of Cancer Survivorship -- Long-Term Psychological Well-Being: Strategies for Assessment and Intervention -- Disparities in Care for Cancer Survivors -- Cancer Survivorship Plans: A Paradigm Shift in the Delivery of Quality Cancer Care -- Optimizing Health: Primary Care -- Optimizing Health: Oncology Care -- Optimizing Survivorship Care: Academic and Community Clinic Models -- The Final Phase of Cancer Survivorship: End-of-Life Care -- Building a Critical Mass of Health-Care Providers, Administrators, and Services for Cancer Survivors -- Epidemiology of Cancer Recurrence, Second Primary Cancer, and Comorbidity Among Cancer Survivors -- Health Economics and Cancer Survivorship -- Human Factors Engineering: Targeting Systems for Change -- Cancer Survivorship and National Health Reform -- Quality Health Care for Cancer Survivors.
  • The Nature of cancer and its psychosocial challenges -- Why work with couples? -- Assessing the couple's adjustment to cancer -- Integrating tasks of illness into the couple's daily routine -- Building cognitive coping skills -- Communicating support -- Expanding the couple's coping skills -- Enhancing sexuality and body image -- Helping children to cope when a mother has cancer -- Living with cancer after treatment ends.
  • Hematologic cancers 2012, Springer
  • Hematologic malignancies 2007, Springer
  • Part 1. Background: Biology, Physiology and Pharmacology -- Part 2. The Colony-Stimulating Factors -- Part 3. The Erythroid-Stimulating Agents -- Part 4. The Thrombopoietic Agents -- Part 5. Special Considerations.
  • Hepatocellular carcinoma 2011, Springer
    Epidemiology and pathogenesis of hepatocellular carcinoma -- Biology of hepatocellular carcinoma -- Hepatocellular cancer: pathologic considerations -- Screening program in high-risk populations -- Staging of hepatocellular carcinoma -- Multidisciplinary care of the hepatocellular carcinoma patient -- Evidence-based guidelines for treatment of hepatocellular carcinoma in Japan -- Hepatocellular carcinoma arising in the non-viral, non-alcoholic liver -- Liver resection for hepatocellular carcinoma -- Ultrasound-guided liver resection for hepatocellular carcinoma -- Portal vein embolization prior to resection -- Laparoscopic liver resection for HCC: a European perspective -- Laparoscopic liver surgery for the management of hepatocellular carcinoma: the American perspective -- Liver transplant for hepatocellular carcinoma -- Vascular resection for hepatocellular carcinoma -- Radiofrequency ablation for hepatocellular carcinoma -- Microwave ablation and hepatocellular carcinoma -- Transarterial chemoembolization -- Chemoembolization with drug-eluting beads -- Yttrium-90 radioembolotherapy for hepatocellular carcinoma -- Cytotoxic chemotherapy and endocrine therapy for hepatocellular carcinoma -- Targeted therapies for hepatocellular carcinoma -- The future: combination systemic therapy for hepatocellular carcinoma -- Follow-up and salvage therapy for recurrent hepatocellular carcinoma.
  • Epidemiology of hepatocellular carcinoma -- Environmental carcinogens and risk for human liver cancer -- Primary liver cancer: chemical carcinogenesis -- Molecular mechanisms of hepatocellular carcinoma: insights to therapy -- Genomic profiling of human hepatocellular carcinoma -- Pathologic aspects of hepatocellular tumors -- Hepatocellular carcinoma associated with hepatitis B virus -- Hepatitis C and hepatocellular carcinoma -- Metabolic disease and hepatocellular carcinoma -- Clinical features and a clinician's diagnostic approach to hepatocellular carcinoma -- Screening and biomarkers for hepatocellular carcinoma -- Use of imaging techniques to screen for hepatocellular carcinoma -- MRI for detection and evaluation of hepatocellular carcinoma -- Ultrasound of hepatocellular carcinoma: the important contribution of contrast enhancement -- Percutaneous ethanol injection -- Radiofrequency ablation of hepatocellular carcinoma -- Resection of hepatocellular carcinoma -- Liver transplantation for hepatocellular carcinoma -- Living donor liver transplantation for hepatocellular carcinoma -- Medical therapy of HCC -- Percutaneous interventional technique for intra-arterial chemoembolization -- Molecular targeted therapies for HCC -- Radiation therapy for hepatocellular carcinoma -- Psychosocial issues in hepatocellular carcinoma -- Putting it all together.
  • High-grade gliomas 2007, Springer
    Histologic classification of high-grade gliomas / Richard A. Prayson -- Molecular classifications / Gregory N. Fuller-- Pediatric high-grade glioma / Bruce H. Cohen -- Adult high-grade glioma / Nicholas Butowski, Susan Chang -- Computerized tomography / Manzoor Ahmed, Thomas J. Masaryk -- Magnetic resonance imaging / Paul M. Ruggieri -- Magnetic resonance spectroscopy / G. Evren Keles, Soonmee Cha, Mitchell S. Berger -- Imaging tumor biology: physiological and molecular insights / Timothy P. L. Roberts, Andrea Kassner -- Nuclear imaging of gliomas / Alexander M. Spence ... [et al.] -- Magnetoencephalography / Michael P. Steinmetz, Jurgen Luders, Edward C. Benzel -- General considerations / Glen H. J. Stevens -- Surgical techniques / Gene H. Barnett -- Radiation therapy / Hiral K. Shah, Minesh P. Mehta -- Brachytherapy / Marcus L. Ware, P. K. Sneed, Michael W. McDermot -- Radiosurgery / John H. Suh, Gene H. Barnett -- Chemotherapy / Manmeet Singh Ahluwalia, David M. Peereboom -- Nursing considerations / Kathleen Lupica, Gail Ditz -- Convection-enhanced delivery / Andrew A. Kanner -- Immunotoxins for glioma therapy / Syed Rafat Husain, Raj K. Puri -- Small molecule agents / Michael Vogelbaum, Tina Thomas -- Cytokine immuno-gene therapy for malignant brain tumors / Roberta P. Glick ... [et al.] -- Monoclonal antibodies / Abraham Boskovitz ... [et al.] -- Clinical trials of oncolytic viruses for gliomas / E. Antonio Chiocca, M. L. Lamfers -- Biological modifiers / Alexander Mason, Steven Toms, Aleck Hercbergs -- Gene therapy / Maciej S. Lesniak, Alessandro Olivi -- Boron neutron capture therapy of brain tumors: current status and future prospects / Rolf F. Barth ... [et al.] -- Photodynamic therapy / Bhadrakant Kavar, Andrew H. Kaye.
  • Hilar Cholangiocarcinoma 2013, Springer
    This is a multi-author book on hilar cholangiocarcinoma, written by an international team of world-renowned experts covering topics in their respective areas of expertise. There are altogether 71 authors from 14 countries/regions, mainly Argentina, Australia, China, Germany, Italy, Japan, Korea, Malaysia, Thailand, the Netherlands, the United Kingdom and the United States of America.This book aims to provide an up-to-date, fully referenced text that is as succinct as possible, but as comprehensive as necessary, addressing all topics in hilar cholangiocarcinoma.
  • Histone code and beyond 2006, Springer
  • Histone deacetylases 2006, Springer
    Histone deacetylase 1 / Dominique Meunier and Christian Seiser -- Biochemistry of multiprotein HDAC complexes / Alejandro Vaquero, Michael Scher, and Danny Reinberg -- The biology of HDAC3 / Edward Seto -- The biology of HDAC8, a unique class I histone deacetylase / David Waltregny and Vincent Castronovo -- Regulation of muscle gene expression by histone deacetylases / Timothy A. McKinsey and Eric N. Olson -- The class IIA histone deacetylases: functions and regulation / Herbert G. Kasler and Eric Verdin -- Histone deacetylases in the response to misfolded proteins / J. Andrew McKee and Tso-Pang Yao -- Evolution of sirtuins from archaea to vertebrates / Roy A. Frye -- Structure of the Sir2 family of NAD+-dependent histone/protein deacetylases / Kehao Zhao and Ronen Marmorstein -- The enzymology of Sir2 proteins / Margie T. Borra and John M. Denu -- The class III protein deacetylases: homologs of yeast Sir2P / Bjoern Schwer ... [et al.] -- HDAC inhibitors: discovery, development, and clinical impacts / Akihiro Ito, Norikazu Nishino, and Mitsuaki Yoshida -- Cell cycle targets of histone deacetylase inhibitors / Brian Gabrielli -- HDAC inhibitors: an emerging anticancer therapeutic strategy / Paul Kwon, Meier Hsu, Dalia Cohen, and Peter Atadja.
  • Histone deacetylases 2011, Springer
    K-acetylation and its enzymes: overview and new developments / Juliette Adjo Aka, Go-Woon Kim, Xiang-Jiao Yang.-- Biology of HDAC in cancer: the nuclear and epigenetic components / Astrid Hagelkruys, Anna Sawicka, Magdalena Rennmayer, Christian Seiser.-- Deacetylation of nonhistone proteins by HDACs and the implications in cancer / Lirong Peng, Edward Seto.-- Biology and therapeutic implications of HDACs in the heart / Timothy A. McKinsey.-- HDACs in skeletal muscle remodeling and neuromuscular disease / Bryan J. Simmons, Todd J. Cohen, Richard Bedlack, Tso-Pang Yao.-- Rationale for HDAC inhibitor therapy in autoimmunity and trasplantation / Wayne W. Hancock.-- Role of mammalian sirtuins in the regulation of metabolism, aging, and longevity / Akiko Satoh, Liana Stein, Shin Imai.-- Mictochondrial sirtuins in the regulation of mictochondrial activity and metabolic adaption / David B. Lombard, Daniel X. Tishkoff, Jianjun Bao.-- Characterization of nuclear sirtuins: molecular mechanisms and physiological relevance / Debra Toiber, Carlos Sebastian, Raul Mostoslavsky.-- Structural biology of human netal-dependent histone deacetylases / Matthieu Schapira.-- Sirtuin modulators / Sumit S. Mahajan, Vid Leko, Julian A. Simon, Antonio Bedalov.
  • This bookprovides an easily comprehensible and practicable framework for standardised histopathology reports in surgical cancer. It details the gross description, histological classification, tumor differentiation, extent of local tumor spread, involvement of lymphovascular channels, lymph nodes and excision margins of the common carcinomas and also summarises non-carcinomatous malignancies. The 7th edition TNM and WHO classifications of cancers are incorporated, with comments on any associated pathology, diagnostic clues and prognostic criteria. Staging information is supplemented visually by line diagrams. Each chapter has a more formal introductory paragraph than in the previous edition,giving epidemiological, clinical, investigative and treatment summary details, and chapter references are updated; specimen type notes new clinical procedures. Other pathology includes updated immunophenotypic expression with use of newantibodies and molecular techniques. The impact of these ancillary investigations on diagnosis, and as biomarkers of prognosis and prediction of response to treatment is summarised. The effect of adjuvant treatments on cancers is also noted. Experience based clues are given throughout as aids to tumor typing, grading, staging and gauging prognosis and response to treatment. The key information in this book equips the pathologist to produce high quality, clinically appropriate histopathology reports, and to participate in contemporary multidisciplinary team management of patients with surgical cancer. Histopathology Reporting: Guidelines for Surgical Cancer, Third Edition is invaluable for trainee and consultant diagnostic histopathologists all over the world.
  • Hodgkin lymphoma 2011, Springer
  • Household Use of Solid Fuels -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale -- -- High-temperature Frying -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale
  • HPV and cervical cancer 2012, Springer
    Infection and Cervical Cancer: An Old Fact with a Recent Solution /Lutz Gissman --Human Papillomavirus: Natural History of a Viral Infection in the Genesis of a Cancer /Franco Borruto and Ciro Comparetto --The Immunobiology of Human Papillomavirus Associated Oncogenesis /Peter L. Stern and Mark H. Einstein --The Epidemiology of Cervical Cancer /Xavier Castellsagué, Laia Bruni, Laia Alemany, Mireia Diaz and Silvia de Sanjosé, et al. --The Basic Elements of a Correct Diagnosis: From Cytohistopathology to Screening /Franco Borruto and Ciro Comparetto --Human Papillomavirus DNA Testing: What, How, and When /Ciro Comparetto and Franco Borruto --Colposcopic Appearance of HPV Infection /Santiago Dexeus, Montserrat Cararach and Damian Dexeus --Multiple Aspects of Human Papillomavirus Infections /Franco Borruto and Ciro Comparetto --Prevention of HPV-Associated Diseases in the United States /Diane M. Harper --Immunogenicity, Efficacy, Effectiveness and Overall Impact of HPV Vaccines /Matti Lehtinen, Pekka Nieminen, Dan Apter, Proscowa Namujju and Kari Natunen, et al. --Treatment, Follow-up, and Prevention of Papillomavirus Infection and Cervical Cancer /Franco Borruto and Ciro Comparetto --Therapeutic Vaccines for HPV Infection /Margaret Stanley --Perspectives on Therapeutic HPV Vaccines: Where Are We Now? /Connie Wang, Barbara Ma, Alexander Chen, Chien-Fu Hung and T. C. Wu.
  • Human cancer viruses 2008, Karger
    Molecular epidemiology of human papillomavirus infection -- / Gillison, M.L -- Molecular pathogenesis of the human papillomavirus / Mao, C.-P., Wu, T.-C -- Human papillomavirus vaccines / Roden, R., Hung, C.-F., Monie, A., Wu, T.-C -- Hepatitis C virus genetics and the discovery of mechanism based inhibitors of the Ns3/4A protease and NS5B polymerase / LaFemina, R.L -- Role of the hepatitis B virus in hepatocellular carcinoma / Toh, S.-T., Lee, C.G -- Carcinogenesis induced by hepatitis B virus / Cougot, D., Buendia, M.-A., Neuveut, C -- Disease and pathogenesis associated with Epstein-Barr virus / Ambinder, R.F -- The biology and molecular biology underlying Epstein-Barr virus oncogenesis / Martin, H.J., Hayward, S.D -- Kaposi-sarcoma-associated herpesvirus clinical diseases and viral pathogenesis / Damania, B., Dittmer, D.P. -- Molecular biology of human herpesvirus 8 neoplasia / Chaudhary, P.M., Nicholas, J -- Human cancer viruses. Human T cell leukemia virus type 1 and 2: mechanisms of pathogenesis / Arnold, J., Green, P.L -- Chromosomal instability and human T cell leukemia virus 1 transformation / Chi, Y.-H., Jeang, K.-T.
  • Pt. 1. Multistep models -- pt. 2. Prostate cancer/stem cells -- pt. 3. Breast cancer/stem cells -- pt. 4. Multistep/genes.
  • Human papillomavirus 2009, Springer
  • 1. Human Papillomavirus (HPV) infection -- 2. Studies of cancer in humans -- 3. Studies of animal papillomaviruses -- 4. Molecular mchanisms of HPV-induced carcinogenesis -- 5. Summary of data reported and evaluation -- 6. References
  • Association between cancer and "acid mucopolysaccharides" : an old concept comes of age, finally -- Hyaluronan-CD44 interactions and chemoresistance in cancer cells -- Growth factor regulation of hyaluronan deposition in malignancies -- Hyaluronan binding protein 1 (HABP1/p32/gClqR) : a new perspective in tumor development -- CD44 meets Merlin and Ezrin : their interplay mediates the pro-tumor activity of CD44 and tumor-suppressing effect of Merlin -- Hyaluronan-mediated CD44 interaction with receptor and non-receptor kinases promotes oncogenic signaling, cytoskeleton activation, and tumor progression -- Adhesion and penetration : two sides of CD44 signal transduction cascades in the context of cancer cell metastasis -- Involvement of CD44, a molecule with a thousand faces, in cancer dissemination -- RHAMM/HMMR : an itinerant and multifunctional hyaluronan binding protein that modifies CD44 signaling and mitotic spindle formation -- Altered hyaluronan biosynthesis in cancer progression --Hyaluronidase : both a tumor promoter and suppressor -- The hyaluronidases in cancer biology -- Hyaluronan fragments : informational polymers commandeered by cancers -- Hyaluronan in human tumors : importance of stromal and cancer cell-associated hyaluronan -- The oncofetal paradigm revisited : MSF and HA as contextual drivers of cancer progression -- Hyaluronan synthesis and turnover in prostate cancer -- Role of hyaluronan in melanoma progression -- Role of hyaluronan metabolism in the initiation, invasion, and metastasis of breast cancer -- Clinical use of hyaluronidase in combination cancer chemotherapy : a historic perspective -- Exploring the hyaluronan:CD44 interaction for cancer therapy -- Hyaluronidase-2 and its role as a cell-entry receptor for sheep retroviruses that cause contagious respiratory tract cancers.
  • "Advances in computed tomography have made it possible to detect small lung cancers, which has changed lung cancer surgery from lobectomy to a lesser lobar resection such as a segmentectomy or wedge resection. Although wedge resection is a simple procedure, it has a higher risk of hilar lymph node or surgical margin recurrence than does a lobectomy. On the other hand, segmentectomy is a well-known curative surgery for small lung cancers. It is difficult to perform accurately, however, because of its anatomical complexity, which makes surgeons hesitant to use it. Illustrated Anatomical Segmentectomy for Lung Cancer provides readers a detailed explanation of segmentectomy with numerous easy-to-understand color illustrations showing the precise segmental anatomies for each pattern of the procedure. To better illustrate an accurate anatomical segmentectomy, the text shows details of anatomy during the procedure. Up to 25 patterns can be involved, each of which is shown in approximately 10 illustrations."--publisher's website
  • Image-Guided Cancer Therapy: A Multidisciplinary Approach provides clinicians with in-depth coverage of the growing, dynamic field of interventional oncology. Combining the knowledge of expert editors and authors into one powerhouse reference, this book looks at tumor ablation, HIFU, embolic therapies, emerging technologies, and radiation therapy throughout the body (liver, bone, breast, gynecologic and prostate cancers, to name just a few), and includes discussion of different imaging modalities. In the words of Peter Mueller, MD, author of the books Foreword: The senior authors are all world renowned experts in interventional oncology, which is another example of the high quality authorship and experience that is brought to this book. The later chapters discuss therapies that are simply not covered in any other source. Everyone who is doing or wants to do ablation therapies and interventional oncology will face a time when they will be asked to use their expertise in less used and less investigated areas. There is nowhere else where the reader can get information on the prostate, breast, and gynecologic areas, and especially pediatrics. This book is an outstanding contribution to the literature and will become a must read for all physicians who are interested in Interventional Oncology.
  • Imaging in oncology 2008, Springer
    Anatomic, physiologic and metabolic imaging in neuro-oncology / Sanjeev Chawla, Harish Poptani, and Elias R. Melhem -- Imaging of spinal tumors / Izlem Izbudak ... [et al.] -- PET imaging of brain tumors / Alan J. Fischman -- Extracranial head and neck neoplasms: role of imaging / Myria Petrou and Suresh K. Mukherji -- Imaging of thoracic malignancies / Subba R. Digumarthy and Suzanne L. Aquino -- Imaging of mediastinal tumors / Scott Moore, Hetal Dave-Verma, and Ajay Singh -- Imaging cardiac tumors / Mannudeep K. Kalra and Suhny Abbara -- Diagnostic imaging and image-guided interventions of hepatobiliary malignancies / Unni Udayasankar ... [et al.] -- Recent advances in imaging of pancreatic neoplasms / Chad B. Rabinowitz, Hima B. Prabhakar, and Dushyant V. Sahani -- Imaging of colorectal carcinoma / Jorge A. Soto -- Imaging of primary malignant tumors of peritoneal and retroperitoneal origin / J. Louis Hinshaw and Perry J. Pickhardt -- Imaging of urinary tract tumors / Michael A. Blake and Mannudeep K. Kalra -- Current status of imaging for adrenal malignant involvement / Michael A. Blake and Mannudeep K. Kalra -- Recent advances in imaging of male reproductive tract malignancies / Jurgen J. Fütterer and J. Roan Spermon -- Imaging of malignant skeletal tumors / Jay Pahade, Aarti Sekhar, and Sanjay K. Shetty -- Radiology of soft tissue tumors including melanoma / M.J. Shelly, P.J. MacMahon, and S. Eustace -- Reticuloendothelium malignancy: current role of imaging / Sunit Sebastian and Brian C. Lucey -- Pediatric malignancies: synopsis of current imaging techniques / Sabah Servaes ... [et al.] -- Interventional radiology in oncology / O.J. O'Connor, J. M. Buckley, and M. M. Maher -- Breast tumor imaging / Deirdre Coll
  • Imaging of kidney cancer 2006, Springer
  • Origin and classification of soft tissue tumors -- Soft tissue tumors in a large referral population: prevalence and distribution of diagnoses by age, sex, and location -- Imaging of soft tissue tumors -- Lipomatous tumors -- Vascular and lymphatic tumors -- Benign fibrous and fibrohistiocytic tumors -- Malignant fibrous and fibrohistiocytic tumors -- Muscle tumors -- Neurogenic lesions -- Synovial tumors -- Extraskeletal osseous and cartilaginous lesions -- Tumors of uncertain histogenesis -- Masses which may mimic soft tissue tumors -- Compartmental anatomy.
  • Which cells control the anti-cancer T cell immune response? -- Antigen presentation -- T cells and cancer cells : components of immune-based anti-cancer therapy -- Anti-cancer vaccines : new approaches -- How and why do we get cancer and can immune-based anti-cancer therapy save us? -- Immunotherapeutic approaches to the treatment of leukemia -- Cancer-induced autoimmunity -- Can we solve the cancer stem cell program and cure cancer using T cell-based immunotherapy? -- Translational immunology and its impact on anti-cancer T cell immunity and the development of immunotherapeutic treatments for cancer -- Dendritic cells, immunotherapy, and the anti-cancer T cell response -- Regulatory T cells, dendritic cells, and the success of immunotherapeutic treatments for cancer -- NK cells and their role in the development of immune-based anti-cancer therapy -- How cancer cells influence the anti-cancer T cell imune response and why this is a problem during the immunotherapeutic treatment of cancer -- The T cell anti-cancer response, T cell regulation, and immunotherapy of neural crest cancers -- The immunological hole : will we fall in?
  • Immunotherapy of cancer 2006, Springer
    Discovery of target molecules for cancer immunotherapy by genetic and bioinformatic approaches -- Current strategies for the identification of immunogenic epitopes of tumor antigens -- Current and future role of natural-killer cells in cancer immunotherapy -- The role of immune monitoring in evaluating cancer immunotherapy -- Statistical analysis of immune response assays -- DNA vaccines for cancer immunotherapy -- Dendritic cells -- Different approaches to dendritic cell-based cancer immunotherapy -- Anti-idiotype antibody vaccines for the immunotherapy of cancer -- Autologous tumor-derived heat shock protein vaccine as a new paradigm for individualized cancer therapeutics -- Tumor-reactive T-cells for adoptive immunotherapy -- T-cell adoptive immunotherapy of cancer: from translational models to clinical significance -- Retroviral-mediated gene transfer for engineering tumor-reactive T-cells -- Harnessing the potential of graft-vs-tumor -- Tumor-induced immune suppression and immune escape: mechanisms and impact on the outcome of immunotherapy of malignant disease -- The tumor microenvironment: regulation of antitumor immunity and implications for immunotherapy -- Manipulation of lymphocyte homeostasis for enhancing antitumor immunity -- Fast-lane evolution in the tumor microenvironment -- Manipulating immunological checkpoints to maximize antitumor immunity -- Interleukin-2 as cancer therapy -- Biological and clinical properties of the type 1 interferons -- Promising g [gamma]-chain cytokines for cancer immunotherapy: interleukins-7, -15, and -21 as vaccine adjuvants, growth factors -- The therapeutic use of natural-killer cells in hematological malignancies -- Antibody therapy for solid tumors -- Antibody therapy for non-Hodgkin's lymphoma -- Approaches to in vivo imaging of cancer immunotherapy -- Design issues for early-stage clinical trials for cancer vaccines -- Monoclonal antibody therapy for cancer.
  • Immunotherapy of cancer 2010, Springer Protocols
    Hypoxic tumors and their effect on immune cells and cancer therapy / Patricia Yotnda, Danli Wu, and Anna May Swanson -- Characterization of regulatory T cells in tumor suppressive microenvironments / Guangyong Peng -- Generation of cytotoxic T lymphocytes for immunotherapy of EBV-associated malignancies / Corey Smith and Rajiv Khanna -- Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy / Dean A. Lee, Michael R. Verneris, and Dario Campana -- Enhanced migration of human dendritic cells expressing inducible CD40 / Natalia Lapteva -- Differentiation of human embryonic stem cells into hematopoietic cells in vitro / Eun-Mi Kim and Nicholas Zavazava -- Gene therapy to improve migration of T cells to the tumor site / Antonio Di Stasi, Biagio De Angelis, and Barbara Savoldo -- Gene therapy to improve function of T cells for adoptive immunotherapy / Concetta Quintarelli, Barbara Savoldo, and Gianpietro Dotti -- Cytokine-FC fusion genes as molecular adjuvants for DNA vaccines / Daniel Hirschhorn-Cymerman and Miguel-Angel Perales -- Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials / Jung Hee Woo ... [et al.] -- Construction of human antibody gene libraries and selection of antibodies by phage display / Thomas Schirrmann and Michael Hust -- Identification of immunogenic peptides of the self-tumor antigen : our experience with telomerase reverse transcriptase / Xochitl Cortez-Gonzalez and Maurizio Zanetti -- Rescue, amplification, purification, and PEGylation of replication defective first-generation adenoviral vectors / Michael A. Barry, Eric A. Weaver, and Sean E. Hofherr -- Adenovirus-mediated interleukin (IL)-24 immunotherapy for cancer / Rajagopal Ramesh ... [et al.] -- Liposomes for gene transfer in cancer therapy / Nancy Smyth Templeton -- Oncolytic HSV as a vector in cancer immunotherapy / Hongtao Li and Xiaoliu Zhang -- Generation of chimeric T-cell receptor transgenes and their efficient transfer in primary mouse T lymphocytes / Linda J. Howland, Nicole M. Haynes, and Phillip K. Darcy -- Multi-walled carbon nanotube (MWCNT) synthesis, preparation, labeling, and functionalization / Babak Kateb ... [et al.] -- Cellular immunotherapy of cancer / Fatma V. Okur and Malcolm K. Brenner.
  • Novel antineoplastics targeting genetic changes in colorectal cancer / Jamal Joudeh...[et al.] -- Update on clinical trials: genetic targets in breast cancer / Bora Lim, Leah V. Cream, Harold A. Harvey -- Impace of genetic targets on cancer therapy in esophagogastric cancer / Yixing Jiang -- Impact of genetic targets on cancer therapy: hapatocellular cancer / Osama Hamed...[et al.] -- Toward the goal of personalizaed therapy in pancreatic cancer by targeting the molecular phenotype / Nelson S. Yee -- Impact of genetic markers on treatment of non-small cell lung cancer / Nicholas Lamparella, Amit Barochia, Salah Almokadem -- Impact of genetic targets on therapy in head and neck squamous cell carcinoma / Irina Chaikhoutdinov, David Goldenberg -- Tyrosine kinase targeted treatment of chronic myelogenous leukemia and other myeloproliferative neoplasms / Ajit Bisen, David F. Claxton -- Targeted tehrapy of multiple myeloma / Nathan G. Dolloff, Giampaolo Talamo -- Current and future trials of targeted therapies and cutaneous melanoma / Matthew S. Evans...[et al.] -- Current approaches to epigenetic therapy for the treatment of mantle cell lymphoma / Vikas Ghai...[et al.] -- Impact of genetic targets on primary brain tumor therapy: what's ready for prime time / O. Zalatimo...[et al.] -- Rational therapy for renal cell carcinoma based on its genetic targets / Jaime Messer, Joseph Drabick, Matthew Kang -- Molecular and genetic markers of follicular-cell thyroid cancer : etiology and diagnostic and therapeutic opportunities / Neerav Goyal...[et al.] -- Genetic targets in pediatric acute lymphoblastic leukemia / Chandrika Gowda, Sinisa Dovat -- Emerging molecular therapies for the treatment of acute lymphoblastic leukemia / Monali Vasekar...[et al.] -- Impact of genetic targets on prostate cancer therapy / Hassan Sheikh...[et al.] -- Small-cell lung cancer : an update on targeted therapues / Monika Joshi, Ayodele Ayoola, Chandra P. Belani -- Impact of genetic targets on cancer therapy in acute myelogenous leukemia / Mithun Vinod Shah, Amit Barochia, Thomas P. Loughran.
  • IMRT, IGRT, SBRT 2007, Karger
  • Over the last 4 years, IMRT, IGRT, SBRT: Advances in the Treatment Planning and Delivery of Radiotherapy has become a standard reference in the field. During this time, however, significant progress in high-precision technologies for the planning and delivery of radiotherapy in cancer treatment has called for a second edition to include these new developments. Thoroughly updated and extended, this new edition offers a comprehensive guide and overview of these new technologies and the many clinical treatment programs that bring them into practical use. Advances in intensity-modulated radiothera.
  • Induction chemotherapy 2011, Springer
  • In remembrance of Rudolf Virchow (1821-1902) / Schmidt, A. -- In memoriam of Rudolf Virchow: a historical retrospective including aspects of inflammation, infection and neoplasia / Schmidt, A., Weber, O.F. -- Aneuploidy and cancer: from correlation to causation / Duesberg, P. ... [et al.] -- Adult stem cell theory of the multi-stage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiated stem cells / Trosko, J.E., Tai, M.-H. -- Helicobacter pylori and gastric neoplasia / Leung, W.K. -- Schistosomiasis and neoplasia / Yosry, A. -- Relevant oncogenic viruses in veterinary medicine: original pathogens and animal models for human disease / Truyen, U., L"chelt, M. -- The inflammatory tumor microenvironment and its impact on cancer development / de Visser, K.E., Coussens, L.M. -- Co-opting macrophage traits in cancer progression: a consequence of tumor cell fusion? / Pawelek, J. ... [et al.] -- Carcinogenesis driven by bone marrow-derived stem cells / Dittmar, T. ... [et al.] -- Chemokine-directed metastasis / Gomperts, B.N., Strieter, R.M. -- Involvement of chemokine receptors in organ-specific metastasis / Zlotnik, A. -- Visualization of tumor cell extravasation / Heyder, C. ... [et al.] -- Options for visualizing metastatic disease in the living body / Helms, M.W., Brandt, B.H., Contag, C. -- Infection, inflammation and neoplasia: an interdisciplinary challenge / Zaenker, K.S.
  • Inflammation and cancer v. 1-2, 2009, Springer Protocols
    v. 2, 2009 Springer Protocols
    v. 1. Experimental models and practical approaches -- v. 2. Molecular analysis and pathways.
  • Basic concepts of inflammation and its role in carcinogenesis -- Inherited syndromes predisposing to inflammation and GI cancer -- Stem cells and inflammation in the intestine -- Acid reflux and oesophageal cancer -- Helicobacter pylori and gastric cancer -- Inflammatory bowel disease and colon cancer -- Primary sclerosing cholangitis -- Chronic inflammation and hepatocellular carcinoma -- Gastrointestinal cancer: current screening strategies -- Targeted drug therapies and cancer -- Genetics of inflammation in the gastrointestinal tract and how it can cause cancer -- Endoscopic methods.
  • Introduction: Why IBC Now? /Naoto T. Ueno and Massimo Cristofanilli --Epidemiology of Inflammatory Breast Cancer /Shannon Wiggins, Sarah Taylor and Melissa Bondy --Clinical Aspect of Inflammatory Breast Cancer: Diagnosis, Criteria, Controversy /Shaheenah Dawood and Vicente Valero --Inflammatory Breast Cancer Registry /Jie S. Willey and Naoto T. Ueno --Pathology: Histomorphometrical Features of IBC - Angiogenesis, Lymphangiogenesis, and Tumor Emboli /Sanford H. Barsky and Fredika M. Robertson --Imaging for the Diagnosis and Staging of IBC /Wei Tse Yang --Surgical Therapy for Inflammatory Breast Cancer /Sarah M. Gainer, Hideko Yamauchi and Anthony Lucci --Radiation Therapy for Inflammatory Breast Cancer /Thomas A. Buchholz, Ian Bristol and Wendy Woodward --Systemic and Targeted Therapy /Hideko Yamauchi, Teruo Yamauchi, Naoto T. Ueno and Vicente Valero --Inflammatory Breast Cancer: Chemotherapy of Metastatic Disease /Anthony Gonçalves and Patrice Viens --The Role of the Multidisciplinary Team in Inflammatory Breast Cancer /Nabila Chowdhury and Sandra M. Swain --High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplantation in Inflammatory Breast Cancer /Yee Chung Cheng and Naoto T. Ueno --Models of Inflammatory Breast Cancer /Lara Lacerda and Wendy A. Woodward --Signaling Pathways in Inflammatory Breast Cancer /Dongwei Zhang and Naoto T. Ueno --Molecules That Drive the Invasion and Metastasis of Inflammatory Breast Cancer /Madhura Joglekar and Kenneth L. van Golen --Inflammatory Mediators as Therapeutic Targets for Inflammatory Breast Cancer /Fredika M. Robertson, Khoi Chu, Rita Circo, Julia Wulfkuhle and Lance Liotta, et al. --Immunology of Inflammatory Breast Cancer /James M. Reuben and Bang-Ning Lee --Angiogenesis and Lymphangiogenesis in IBC: Insights from a Genome-Wide Gene Expression Profiling Study /Peter B. Vermeulen, Gert Van den Eynden, Pascal Finetti, Daniel Birnbaum and Naoto T. Ueno, et al. --Microarray Analysis Identifies an Expression Signature for Inflammatory Breast Cancer /François Bertucci, Pascal Finetti, Max Chaffanet, Patrice Viens and Daniel Birnbaum --Cell Gene Expression Signatures in Inflammatory Breast Cancer /Wendy A. Woodward --The Effect of Systemic Chemotherapy on Minimal Residual Disease in the Blood and Bone Marrow of Patients with Inflammatory Breast Cancer /Luc Y. Dirix, Dieter Peeters, Steven Van Laere and Peter B. Vermeulen --Perspective of Patient Advocacy /Michelle Esteban and Patti Bradfield.
  • Ingested nitrate and nitrite -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale -- -- Cyanobacterial peptide toxins -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale
  • Epidemiology of IGF-1 and cancer / Katharina Nimptsch and Eward Giovannucci -- Aging and cancer : the IGF- I connection / Kalina Biernacka, Claire Perks, and Jeff Holly -- Obesity, type 2 diabetes and cancer / Rosalyn D. Ferguson and Derek LeRoith -- IGF system and breast cancer / Marc A. Becker and Douglas Yee -- The role of insulin-like growth factor signaling in prostate cancer development and progression / Bruce Montgomery, James Dean, and Stephen Plymate -- IGF-1 cellular action and its relationship to cancer : evidence from in vitro and in vivo studies / Rosalyn D. Ferguson ... [et al.] -- Insulin-like growth factor signaling in pediatric sarcomas / Xiaolin Wan, Su Young Kim, and Lee J. Helman -- Cancer genes, tumor suppressors, and regulation of IGF1-R gene expression in cancer / Haim Werner ... [et al.] -- Mouse models of IGF-1R and cancer / Craig I. Campbell, James J. Petrik, and Roger A. Moorehead -- Targeting the insulin-like growth factor-I receptor in cancer therapy / David R. Clemmons -- Targeting insulin-like growth factor receptor 1 (IGF-1R) and insulin receptor signaling by tyrosine kinase inhibitors in cancer / Joan M. Carboni, Mark Wittman, and Fei Huang -- Calories and cancer : the role of insulin-like growth factor-1 / Stephen D. Hursting ... [et al.] -- Cancer cell metabolism / Akash Patnaik, Jason W. Locasale, and Lewis C. Cantley -- Overlaps between the insulin and IGF-I receptor and cancer / Antonino Belfiore and Roberta Malaguarnera.
  • Microenvironmental effects on tumour progression and metastasis -- Role of microenvironment on gene expression, angiogenesis and microvascular function in tumors -- Imaging of angiogenesis in vivo with fluorescent proteins -- The epigenetic influence of the tumor microenvironment on melanoma plasticity -- Dynamics of cell adhesion interactions during melanoma development -- Matrix metalloproteinases: mediators of tumour-host cell interactions -- Role of brain microenvironments in brain metastases -- Influence of the bone microenvironment on breast cancer metastasis to bone -- Interaction of tumour with host stroma in hepatocellular carcinoma -- Dynamic nature of tumour-host interactions within the tumor microenvironment -- Breast cancer progression: a "vicious cycle" of pro-malignancy activities is mediated by inflammatory cells, chemokines and cytokines -- Tumor and host endothelial cell selective interactions and modulation by microenvironmental chemokines: tumor-endothelial cell cross talk specificity -- The role of chemokine receptors, in particular CXCR4, in lymphoma and carcinoma metastasis --Energy homeostasis and the tumor/host interaction: the role of the brain -- Anti-angiogenic and pro-apoptotic effects of dietary restriction in experimental brain cancer: role of glucose and ketone bodies -- Dietary restriction of specific amino acids modulates tumor and host interactions -- Role of tumour microenvironment in chemoresistance -- Integrin-mediated resistance to chemotherapy-induced apoptosis in cancer cells -- Bone metastasis microenvironment participates in the development of androgen ablation refractoriness and chemotherapy resistance of prostate cancer cells residing in the skeleton: clinical implications -- Current and future therapeutic targets of the tumour-host microenvironment -- Bone stromal cells as therapeutic targets in osseous metastasis -- Organtropism of lung cancer metastasis and its molecular targeted therapy -- Maspin: a novel serine protease inhibitor -- Metastasis suppressor genes: a brief review of an expanding field -- Tumor-host interactions at the metastatic site: MKK4, signal transduction and the stress response.
  • Integrative oncology 2008, Springer
    Introduction -- A word of caution: risk of harm associated with alternative complementary/integrative approaches in cancer management and the critical need for quality research to understand and decrease that risk -- Using legal and ethical principles to guide clinical decision making in complementary/integrative cancer medicine -- Communicating with patients about the use of complementary and integrative medicine in cancer care -- The integrative medicine program at The University of Texas M. D. Anderson Cancer Center -- The integrative medicine service at Memorial Sloan-Kettering Cancer Center -- Integrative oncology-Leonard P. Zakim Center: the Dana-Farber Cancer Institute experience -- The Johns Hopkins complementary and integrative medicine service -- Integrative oncology at Mayo Clinic: research informing practice -- Mind-body research in cancer -- Herbs and other botanicals: interactions with pharmaceuticals -- Acupuncture in cancer care at Dana-Farber Cancer Institute: an integrative medical practice -- Acupuncture for the side effects of cancer treatments.
  • This practice-oriented handbook covers complementary and alternative medicine (CAM) practices in pediatric oncology worldwide, with a focus on methods used in Western countries. Provides a road map for establishing integrative pediatric oncology worldwide.
  • Introduction -- Epidemiology and Prevention of Prostate Cancer -- Imaging Localised Prostate Carcinoma -- Patient Selection and Recommendations on Permanent Seed Implantation as Monotherapy for Localized Prostate Cancer -- Patient Selection and Recommendations: HDR -- Prostate Brachytherapy Implantation Treatment Techniques -- HDR Technique -- Pulsed-Dose Rate Brachytherapy in Prostate Cancer -- Imaging for Post-implant Dosimetry -- Dosimetry Planning for Permanent Seeds -- HDR Planning -- Postimplant Dosimetry -- Dose-Response Relationship in Permanent Implant Brachytherapy for Prostate Cancer -- HDR Versus LDR Seeds -- Results of Permanent Prostate Brachytherapy -- Results of HDR Prostate Brachytherapy Treatments -- Results of PDR Treatments: The AMC PDR Experience -- Incidence and Prognostic Factors for Complications After Permanent Interstitial Brachytherapy -- Salvage Treatment for Recurrent Prostate Cancer Following Brachytherapy: For Whom, When and Which? -- Prostate Cancer Brachytherapy: Radiation Protection Issues.
  • Interventional oncology 2012, Springer
  • Interventions in Pulmonary Medicine is an important new volume that addresses all areas of interventional pulmonology, a minimally invasive endoscopic way to diagnose and treat lung disorders. This volume contains dedicated chapters that outline the many issues related to lung cancer, both in early and advanced stages, from diagnosis to personalized treatment. It also covers bronchoscopic therapeutic options to benign conditions that are highly prevalent, such as COPD and asthma. Techniques described in this volume are: laser therapy, argon plasma coagulation therapy, cryotherapy, brachytherapy, placement of intrapleural drainage systems, endoscopic treatment of emphysema, stents in the airway, and thermoplasty for bronchial asthma. Diagnostic procedures that are covered are: medical thoracoscopy, flexible and rigid bronchoscopy, endobronchial ultrasound, electromagnetical navigation, and trends in personalized treatment for lung cancer and other benign lung conditions. Chapters are written by experts and the developers of the techniques that are currently considered gold standard. Evidence-based reviews are presented for all topics and indications, and contraindications are discussed. Interventions in Pulmonary Medicine is a must have for pulmonologists, endoscopists, pulmonary oncologists, ENT physicians, thoracic surgeons, anesthesiologists, and intensive care specialists and their teams.
  • Management of ovarian cancer : the theory / Maurie Markman -- Management of ovarian cancer : clinical trials / Maurie Markman -- A systematic review and meta-analysis of randomized trials / Kenneth Jaaback -- Immunobiology and intraperitoneal immunobiologics in ovarian cancer / Ralph S. Freedman -- Intraperitoneal chemotherapy : technique and complications / Joan L. Walker -- Hyperthermia and chemotherapy : the science / Roger A. Vertrees, Jeffrey M. Jordan, and Joseph B. Zwischenberger -- Hyperthermic intraperitoneal chemotherapy in nongynecologic cancers / Bing Yi, Jason M. Foster, and Brian W. Loggie -- Peritoneal carcinomatosis of colorectal origin / Frans A.N. Zoetmulder -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : experience in France / Olivier Glehen and Francois-Noel Gilly -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : world experience / C. William Helm -- Techniques of delivering hyperthermic intraperitoneal chemotherapy / Jesus Esquivel, Paul H. Sugarbaker, and C. William Helm -- Future directions in the delivery of hyperthermic intraperitoneal chemotherapy / Scott Richard and Robert P. Edwards.
  • Current chemotherapy of ovarian cancer -- Principles of intraperitoneal chemotherapy -- Intraperitoneal chemotherapy: phase III trials -- Criteria for using intraperitoneal (IP) chemotherapy for advanced ovarian cancer -- Selection and placement of intraperitoneal catheters for IP chemotherapy for ovarian cancer -- Selection of drugs for intraperitoneal chemotherapy for ovarian cancer -- Administration guidelines for intraperitoneal chemotherapy for ovarian cancer -- Novel drugs for intraperitoneal therapy for ovarian cancer -- Cytoreductive surgery and perioperative intraperitoneal chemotherapy: an ongoing research effort -- Health-related quality of life and patient-reported outcomes.
  • Invasive bladder cancer 2007, Springer
  • The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This publication presents two IPCS frameworks originally published in Critical Reviews in Toxicology. Part 1 contains the IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans, along with three case studies illustrating its application. Part 2 contains the IPCS Framework for Analyzing the Relevance of a Non-Cancer Mode of Action for Humans. The frameworks provide a means of ensuring a transparent evaluation of the data, identification of key data gaps and of information that would be of value in the further risk assessment of the chemical in question.--Publisher's description.
  • Kidney cancer 2012, Springer
  • Killer lymphocytes 2005, Springer
  • Kinetochore 2009, Springer
    Centromeres and kinetochores : an historical perspective /Kerry S. Bloom --The basics of chromosome segregation /Mitsuhiro Yanagida --The centromere /Beth A. Sullivan --Neocentromeres /Owen J. Marshall and K.H. Andy Choo --Human artificial centromeres : de novo assembly of functional centromeres on human artificial chromosomes /Hiroshi Masumoto, Teruaki Okada, and Yasuhide Okamoto --Kinetochore composition, formation, and organization /Tatsuo Fukagawa and Peter De Wulf --Evolution of centromeres and kinetochores : a two-part fugue /Paul B. Talbert, Joshua J. Bayes, and Steven Henikoff --Mitotic spindle assembly mechanisms /Rebecca Heald and Claire E. Walczak --Kinetochore-microtubule interactions /Lesley Clayton and Tomoyuki U. Tanaka --Post-translational modifications that regulate kinetochore activity /Chitra V. Kotwaliwale and Sue Biggins --The role of the kinetochore in spindle checkpoint signaling /P. Todd Stukenberg and Daniel J. Burke --Kinetochore regulation of anaphase and cytokinesis /Scott Thomas and Kenneth B. Kaplan --Roles of centromeres and kinetochores in meiosis /Adele L. Marston --The kinetochore-cancer connection /Takeshi Tomonaga --The kinetochore as target for cancer drug development /Song-tao Liu and Tim J. Yen.
  • Part I. Overview of brain tumor survivorship -- Introduction to brain tumor survivorship and historical perspective / Stewart Goldman and Christopher D. Turner -- Late effects of neurosurgery / Arthur J. DiPatri, Martin Pham, and Kenji Muro -- Late effects of CNS radiation therapy / Helen A. Shih, Jay S. Loeffler, and Nancy J. Tarbell -- Late effects of chemotherapy / Sridharan Gururangan -- Late effects of stem cell transplantation in brain tumor survivors / Karina Danner-Koptik, David A. Jacobsohn, and Kimberley J. Dilley -- Effect of cancer treatment on neural stem and progenitor cells / Jörg Dietrich and Santosh Kesari -- The pediatric brain tumor late effects clinic / Kimberly J. Dilley and Barbara Lockart -- Part II. Medical late effects of brain tumor treatment -- Neurological complications in adults / Michelle Monje and Patrick Y. Wen -- Neurological complications in children / Sonia Partap and Paul Graham Fisher -- Strokes among childhood brain tumor survivors / Daniel C. Bowers -- Endocrine late effects: manifestations and treatments / Jason R. Fangusaro and Elizabeth Eaumann Littlejohn -- Ocular consequences and late effects of brain tumor treatments / María E. Echevarría and Joanna L. Weinstein -- Auditory late effects of chemotherapy / Anna K. Meyer and Nancy M. Young -- Reproductive health issues in survivors of childhood and adult brain tumors / Tress Goodwin, B. Elizabeth Delasobera, and Paul Graham Fisher -- Cancer predisposition syndromes / Joanna L. Weinstein, Kanyalakshmi Ayyanar, and Melody A. Watral -- Secondary neoplasms following treatment for brain tumors / Joanna L. Weinstein, Kanyalakshmi Ayyanar, and Melody A. Watral.
  • Leukaemia 2003, Wellcome Trust
  • Leukemia 2009, Springer Protocols
    An overview: from discovery of candidate mutations to disease modeling and transformation mechanisms of acute leukemia / C.W. So -- Backtracking of leukemic clones to birth / J. Wiemels, M. Kang and M. Greaves -- Fluorescence In situ hybridization (FISH) as a tool for the detection of significant chromosomal abnormalities in childhood leukaemia / Z.J. Konn ... [et al.] -- Specialized fluorescence in situ hybridization (FISH) techniques for leukaemia research / L. Kearney and S. Colman -- LDI-PCR: identification of known and unknown gene fusions of the human MLL gene / C. Meyer and R. Marschalek -- Panhandle PCR approaches to cloning MLL genomic breakpoint junctions and fusion transcript sequences / B.W. Robinson and C.A. Felix -- MRD detection in acute lymphoblastic leukemia patients using Ig/TCR gene rearrangements as targets for real-time quantitative PCR / V.H. van der Velden and J.J. van Dongen -- Array-based comparative genomic hybridization as a tool for analyzing the leukemia genome / J.C. Strefford and H. Parker -- Application of SNP genotype arrays to determine somatic changes in cancer / M. Gupta and B.D. Young -- Retroviral/Lentiviral transduction and transformation assay / B.B. Zeisig and C.W. So -- Gene expression profiling of leukemia stem cells / A.V. Krivtsov ... [et al.] -- Humanized model to study leukemic stem cells / D. Bonnet -- Model systems for examining effects of leukemia-associated oncogenes in primary human CD34+ cells via retroviral transduction / M. Wunderlich and J.C. Mulloy -- Ex vivo assays to study self-renewal and long-term expansion of genetically modified primary human acute myeloid leukemia stem cells / J.J. Schuringa and H. Schepers -- Identification and characterization of hematopoietic stem and progenitor cell populations in mouse bone marrow by flow cytometry / J. Yeung and A.C. Wai Eric So -- In vitro differentiation of mouse embryonic stem cells as a model of early hematopoietic development / P. Sroczynska ... [et al.] -- Analysis of the mouse placenta as a hematopoietic stem cell niche / K. Ottersbach and E. Dzierzak -- Identification of protein interaction partners by the yeast two-hybrid system / M.P. Garcia-Cuellar, D. Mederer and R.K. Slany -- Complete array of HOX gene expression by RQ-PCR / G.J. Dickson, T.R. Lappin and A. Thompson -- Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias / M.E. Figueroa, A. Melnick and J.M. Greally -- Chromatin immunoprecipitation (ChIP) for analysis of histone modifications and chromatin-associated proteins / T.A. Milne, K. Zhao and J.L. Hess.
  • Inflammation and cancer: the role of the immune response and angiogenesis /Angus G. Dalgleish and Ken O'Byrne --Chronic inflammation and pathogenesis of GI and pancreatic cancers /Lindsey N. Jackson and B. Mark Evers --Cytokines, NF-[kappa]B, microenvironment, intestinal inflammation and cancer /Arndt J. Schottelius and Harald Dinter --Regulation of NF-[kappa]B transcriptional activity /Linda Vermeulen, Wim Vanden Berghe and Guy Haegeman --The role of immune cells in the tumor microenvironment /Theresa L. Whiteside --Tumor-microenvironment interactions: the seletcin-selectin ligand axis in tumor-endothelium cross talk /Isaac P. Witz --CD95L/FasL and trail in tumour surveillance and cancer therapy /Harald Wajant --Infection & neoplastic growth 101: the required reading for microbial pathogens aspiring to cause cancer /Jessica Berout and Andrei Thomas-Tikhonenko --Cytokines as mediators and targets for cancer cachexia /Josep M. Argilés, Sílvia Busquets and Francisco J. López-Soriano --Targeting NF-[kappa]B in anticancer adjunctive chemotherapy /Burkhard Haefner.
  • Structure and synthesis of lipid A / Shoichi Kusumoto, Masahito Hashimoto and Kazuyoshi Kawahara -- Conformation and supramolecular structure of lipid A / Klaus Brandenburg and Ulrich Seydel -- Interactions between lipid A and serum proteins / Jèorg Andrèa ... [et al.] -- The lipid A receptor / Kiyoshi Takeda -- Lipid A receptor TLR4-mediated signaling pathways / Masahiro Yamamoto and Shizuo Akira -- Lipid A-induced responses in vivo / Néjia Sassi ... [et al.] -- Lipid A-mediated tolerance and cancer therapy / Cheryl E. Rockwell, David C. Morrison and Nilofer Qureshi -- Lipid A in cancer therapies : preclinical results / Daniele Reisser and Jean-François Jeannin -- Monophosphoryl lipid A (MPL) as an adjuvant for anti-cancer vaccines : clinical results / Christopher W. Cluff -- Antitumoral effects of lipids A : clinical studies / Marc Bardou and Danièle Reisser.
  • Liver cancer 2009, Springer
  • Liver metastases 2009, Springer
  • Liver metastasis 2011, Springer
  • OBJECTIVES: We prepared this report on the comparative effectiveness and harms of lung-directed nonsurgical therapies for non-small-cell lung cancer (NSCLC) in three distinct patient populations: (1) patients with stage I NSCLC who are not surgical candidates (Key Question 1), (2) patients with stage I NSCLC who are deemed operable but decline surgery (Key Question 2), and (3) patients with endoluminal NSCLC causing obstruction (Key Question 3). For stage I NSCLC, the local nonsurgical interventions could include conformal radiotherapy modalities and radiofrequency ablation (RFA). For patients with airway obstruction due to an endoluminal NSCLC, local nonsurgical interventions could include those for the stage I setting, as well as conventional wide-field radiotherapy, brachytherapy, laser and mechanical debridement, endoluminal stents, cryoablation, and photodynamic therapy. Surgical resection of any type is not considered as a comparator for any of the Key Questions. DATA SOURCES: MEDLINE(r), Embase(r), and the Cochrane Controlled Trials Registry were searched from January 1, 1995, to July 25, 2012. A search of the gray literature included databases with regulatory information, clinical trial registries, abstracts and conference papers, and information from manufacturers. REVIEW METHODS: We sought studies reporting overall survival, cancer-specific survival, local control, symptom relief, adverse events, and quality of life among our populations of interest. Data were abstracted for each Key Question by a team of reviewers, with independent data verification. Study quality and the risk of bias of randomized controlled trials (RCTs) were assessed using the United States Preventive Services Task Force criteria. The quality and risk of bias of single-arm studies were assessed using the Carey and Boden criteria. The strength of the body of evidence was assessed according to the Agency for Healthcare Research and Quality Methods Guide. RESULTS: In our searches, we identified 4,648 unique titles and screened 1,178 in full text. Of the latter, 55 met the inclusion criteria. Thirty-five studies were relevant to Key Question 1, considering medically inoperable patients with stage I NSCLC; 6 were relevant to Key Question 2, considering medically operable patients with stage I NSCLC who decline surgery; and 17 were relevant to Key Question 3, considering patients with inoperable endoluminal NSCLC causing symptoms of obstruction. Three studies addressed both Key Questions 1 and 2. All studies relevant to Key Questions 1 and 2 were single-arm design, prospective (n=15), retrospective (n=21), or not specified (n=2). Among 17 papers included for Key Question 3, 5 were RCTs, 1 was a nonrandomized comparative study, and 11 were single-arm studies. Because comparative study evidence on RFA and debridement and stenting was unavailable for Key Question 3, we included evidence from two single-arm studies involving stents and one on RFA. All RCTs were of poor quality. Only one comparison was available per study, with no two studies examining the same set of interventions. Outcomes of therapy for all Key Questions included overall survival, adverse effects, and quality of life. CONCLUSIONS: Evidence on localized nonsurgical therapies for patients with stage I NSCLC who are not surgical candidates or who decline surgery consists only of single-arm studies, with no direct comparisons among interventions. The best evidence for NSCLC patients with endoluminal obstruction consists of poor-quality single RCTs for each comparison; we did not identify evidence that permitted us to draw conclusions based on indirect comparisons. Overall, evidence is insufficient to permit conclusions on the comparative effectiveness of local nonsurgical therapies for inoperable or operable patients with stage I NSCLC or inoperable NSCLC patients with endoluminal tumor causing pulmonary symptoms.
  • Lung cancer 2010, Springer
  • Lung cancer 2003, Springer Protocols
    v. 2 Springer Protocols
    v. 1. Molecular pathology methods and reviews -- v. 2. Diagnostic and therapeutic methods and reviews.
  • Lung cancer imaging 2013, Springer
    While specialists often guide the care to lung cancer patients, it is often a general radiologist who is left to interpret studies that impact patient care and management. Lung Cancer Imaging provides a comprehensive guide to the diagnosis, staging and overview of the management of lung cancer relevant to practicing radiologists so that they can better understand the decision making issues and provide more directed and useful communication to the treating physicians. It Primary Care physicians will also find this book valuable to understand the relevant issues that they face when one of their.
  • Lung cancer metastasis 2009, Springer
    Lung Cancer: Overview / Shirish M. Gadgeel and Gregory P. Kalemkerian -- Hallmarks of Metastasis / M. Roshni Ray and David M. Jablons -- Tumor Stem Cells and Metastasis / Jaclyn Y. Hung -- Epithelial-Mesenchymal Transition as a Mechanism of Metastasis / Katia Savary, Stefan Termén, Sylvie Thuault, Venkateshwar Keshamouni and Aristidis Moustakas -- Mechanisms of Tumor Cell Migration and Invasion in Lung Cancer Metastasis / Charles Kumar Thodeti and Kaustabh Ghosh -- Immunologic Mechanisms in Lung Carcinogenesis and Metastasis / Jay M. Lee, Jane Yanagawa, Saswati Hazra, Sherven Sharma and Tonya Walser, et al. -- Angiogenesis and Angiogenic Diversity in Lung Cancer Metastasis / Douglas A. Arenberg -- Chemokines in Lung Cancer Metastasis / Borna Mehrad, Ellen C. Keeley and Robert M. Strieter -- Molecular Control of Lymphatic Metastasis in Lung Cancer / Mark M. Fuster and Judith A. Varner -- Carcinoma-Associated Fibroblasts in Lung Cancer / Roya Navab, Bizhan Bandarchi and Ming-Sound Tsao -- The Role of Tumor-Associated Macrophages and Other Innate Immune Cells in Metastatic Progression of Lung Cancer / Zvi G. Fridlender, M. Cecilia Crisanti and Steven M. Albelda -- Experimental Animal Models for Studying Lung Cancer / Jiang Liu and Michael R. Johnston -- Molecular Imaging in Lung Cancer Metastases / Mahaveer Swaroop Bhojani, Shyam Nyati, Hyma R. Rao, Brian D. Ross and Alnawaz Rehemtulla -- Biomarker Discovery for Metastatic Disease / Gilbert S. Omenn and James D. Cavalcoli -- Current Clinical Management of Metastatic Lung Cancer / Bryan J. Schneider and Suresh S. Ramalingam -- Site-Directed Therapy for Lung Cancer Metastases / Kevin S Oh, Baskaran Sundaram, Venkataramu Krishnamurthy, Allan Pickens and Malini Venkatram, et al. -- Systems Approach for Understanding Metastasis / Peter J. Woolf, Angel Alvarez and Venkateshwar G. Keshamouni.
  • Etiology and epidemiology -- Lung cancer biology -- Screening/early detection/prevention -- Pathology and molecular classification -- Clinical presentation, diagnosis, staging, and prognosis -- Surgery -- Radiation therapy -- Chemotherapy -- Multimodality therapy of NSCLC -- Treatment of small cell lung cancer -- Novel therapeutic strategies -- Palliation and special considerations -- Other thoracic tumors.
  • "Lung cancer remains the leading cause of cancer-related deaths worldwide. Early diagnosis can improve the effectiveness of treatment and increase a patient's chances of survival. Thus, there is an urgent need for new technology to diagnose small, malignant lung nodules early as well as large nodules located away from large diameter airways because the current technology, namely, needle biopsy and bronchoscopy, fail to diagnose those cases. However, the analysis of small, indeterminate lung masses is fraught with many technical difficulties. Often patients must be followed for years with serial CT scans in order to establish a diagnosis, but inter-scan variability, slice selection artifacts, differences in degree of inspiration, and scan angles can make comparing serial scans unreliable. Lung Imaging and Computer Aided Diagnosis brings together researchers in pulmonary image analysis to present state-of-the-art image processing techniques for detecting and diagnosing lung cancer at an early stage. The book addresses variables and discrepancies in scans and proposes ways of evaluating small lung masses more consistently to allow for more accurate measurement of growth rates and analysis of shape and appearance of the detected lung nodules. Dealing with all aspects of image analysis of the data, this book examines: Lung segmentation, Nodule segmentation, Vessels segmentation, Airways segmentation, Lung registration, Detection of lung nodules, Diagnosis of detected lung nodules, Shape and appearance analysis of lung nodules. Contributors also explore the effective use of these methodologies for diagnosis and therapy in clinical applications. Arguably the first book of its kind to address and evaluate image-based diagnostic approaches for the early diagnosis of lung cancer, Lung Imaging and Computer Aided Diagnosis constitutes a valuable resource for biomedical engineers, researchers, and clinicians in lung disease imaging"--Provided by publisher.
  • Lymphoma 2005, Springer Protocols
  • Lymphoma 2013, Springer
    Recently, understanding the molecular pathogenesis of malignant lymphomas has led to improvement in the diagnostic precision and to the identification of a variety of molecular therapeutic targets. In addition, new drugs have been approved in the US and Europe, resulting in changes in the standard of care of several types of lymphoid malignancies. Comprehensive in scope and developed by a team of internationally renowned authors, Lymphoma: Diagnosis and Treatment provides a timely update on the most important advances in the biology, diagnosis, and therapy of lymphomas. As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies.
  • 1. Noninvasive Breast Cancer /Robert H. I. Andtbacka ... [et al.] --2. Invasive Breast Cancer /Jonathan S. Zager ... [et al.] --3. Melanoma /Timothy M. Pawlik and Jeffrey E. Gershenwald --4. Nonmelanoma Skin Cancer /Nestor F. Esnaola and Keith M. Heaton --5. Soft Tissue and Bone Sarcoma /Keith A. Delman and Janice N. Cormier --6. Cancer in the Head and Neck /Kenneth A. Newkirk and F. Christopher Holsinger --7. Thoracic Malignancies /Shanda H. Blackmon and Ara A. Vaporciyan --8. Esophageal Carcinoma /Alexander A. Parikh, Ara A. Vaporciyan, and Wayne L. Hofstetter --9. Gastric Cancer /Waddah B. Al-Refaie and Paul F. Mansfield --10. Small-Bowel Malignancies and Carcinoid Tumors /Keith D. Amos and Rosa F. Hwang --11. Cancer of the Colon, Rectum, and Anus /George J. Chang and Barry W. Feig --12. Hepatobiliary Cancers /Eugene A. Choi, Steven E. Rodgers, Syed A. Ahmad, and Eddie K. Abdalla --13. Pancreatic Adenocarcinoma /Rosa F. Hwang ... [et al.] --14. Pancreatic Endocrine Tumors and Multiple Endocrine Neoplasia /Jeffrey T. Lenert ... [et al.] --15. Adrenal Tumors /Ricardo J. Gonzalez and Jeffrey E. Lee --16. Carcinoma of the Thyroid and Parathyroid Glands /Keith D. Amos, Mouhammed A. Habra, and Nancy D. Perrier --17. Hematologic Malignancies and Splenic Tumors /Wayne A. I. Frederick ... [et al.] --18. Cancer of Unknown Primary Site /Gauri R. Varadhachary --19. Genitourinary Cancer /Christopher G. Wood and Colin P.N. Dinney --20. Gynecologic Cancers /Brian M. Slomovitz, Pamela T. Soliman, Judith K. Wolf --21. Oncologic Emergencies /Jeffrey D. Wayne and Richard J. Bold --22. Biologic Cancer Therapy /Daniel Albo, Thomas N. Wang, and George P. Tuszynski --23. Pharmacotherapy of Cancer /Judy L. Chase and Chad M. Barnett --24. Reconstructive Surgery in the Cancer Patient /Jules A. Feledy, Jr. Matthew M. Hanasono, and Geoffrey L. Robb --Index.
  • Malignant effusions 2012, Springer
    Morphological and Functional Characteristics of Serous Cavities /Olga V. Lebedinskaya, Irina Zh Shubina, Natalia Yu Anisimova, Alexey N. Kopylov and Mikhail V. Kiselevsky --Pathogenesis of Malignant Effusions /Irina O. Chikileva, Natalia Yu Anisimova, Irina Zh Shubina and Mikhail V. Kiselevsky --Diagnosis and Treatment of Malignant Pleural Effusion /Sergi Call, David Sánchez and Ramón Rami-Porta --Malignant Ascites: Diagnosis and Treatment /Fausto Petrelli and Sandro Barni --Malignant Pericardial Disease /Caroline Chiles and Girish Shroff --Adoptive Immunotherapy of Malignant Effusions /Irina Zh Shubina, Konstantin S. Titov, Irina O. Chikileva, Lev V. Demidov and Mikhail V. Kiselevsky --Hyperthermia and Intracavitary Chemotherapy in Prevention and Treatment of Malignant Effusions /Gianfranco Baronzio, Giammaria Fiorentini, Marco Ballerini, Valter Cassuti and Giorgio Forzenigo, et al.
  • Malignant mesothelioma 2005, Springer
  • Malignant mesothelioma 2011, Springer
  • 1. Background and Epidemiology -- Basic Science of Breast Cancer in Older Patients / Irmgard Irminger-Finger -- Tumor Biology and Pathology / Virginie Durbecq and Denis Larsimont Clinical Epidemiology and the Impact of Co-Morbidity on Survival / Adri C. Voogd, Marieke J. Louwman and Jan Willem W. Coebergh -- 2. Special Considerations in the Management of Older Women -- Comprehensive Geriatric Assessment / Margot A. Gosney -- A Practical Mini-Guide to Comprehensive Geriatric Assessment / Siri Rostoft Kristjansson -- Impact of the Physiological Effects of Aging on the Pharmacokinetics and Pharmacodynamics of Systemic Breast Cancer Treatment / Paul Hamberg, Maja J. A. de Jonge and Caroline M. Seynaeve -- Impact of Hormone Replacement Therapy on Breast Cancer / Toral Gathani and Valerie Beral -- Experiences of a Multidisciplinary Elderly Breast Cancer Clinic: Using the Right Specialists, in the Same Place, with Time / Anne Stotter, Mohammad Tahir, Robert S. Pretorius and Thompson Robinson -- 3. Therapeutics -- Mammographic Breast Screening in Elderly Women / Lynda Wyld -- Primary Endocrine Therapy for the Treatment of Early Breast Cancer in Older Women / Lynda Wyld and Daniel Hind -- Peroperative Radiotherapy / Roberto Orecchia, Giovanni Battista Ivaldi and Maria Cristina Leonardi -- General and Local Anesthetics / Bernadette Th. Veering -- The Surgical Management of Breast Cancer in Elderly Women / Malcolm W. R. Reed, Lynda Wyld and Riccardo A. Audisio -- Breast Reconstruction / Marcus J. D. Wagstaff, Malcolm W. R. Reed and Christopher M. Caddy -- Adjuvant Endocrine Therapy / Laura Biganzoli -- Adjuvant Chemotherapy / Sumanta Kumar Pal, Nilesh Vora and Arti Hurria -- Adjuvant Radiotherapy / Pierre G. M. Scalliet -- Prevention and Treatment of Skeletal Complications / Matthew C. Winter, Helen L. Neville-Webbe and Robert E. Coleman -- Medical Management of Advanced Disease / Hans P. M. W. Wildiers -- The Use of Chemotherapy in Elderly Cancer Patients: Dose Adjusting, Drug Interactions, and Polypharmacy / Lazzaro Repetto and Claudia Di Bartolomeo -- 4. Psychosocial Considerations -- Delayed Presentation of Breast Cancer in Older Women / Lindsay J. L. Forbes and Amanda J. Ramirez -- Patient Decision Making / Martine Extermann -- Culture, Ethnicity, and Race: Persistent Disparities in Older Women with Breast Cancer / Antonella Surbone and Marjorie Kagawa-Singer -- Supportive, Palliative and End-of-Life Care for Older Breast Cancer Patients / Elaine Cachia, Ruth Broadhurst and Sam H. Ahmedzai.
  • Anatomy and Physiology of the Breast -- Congenital and Developmental Abnormalities of the Breast -- Nipple Discharge -- Mastalgia -- Management of Common Lactation and Breastfeeding Problems -- Evaluation of a Breast Mass -- Breast Cancer Epidemiology -- Breast Cancer Screening -- Breast Imaging -- Premalignant and Malignant Breast Pathology -- Lobular Carcinoma in Situ -- Ductal Carcinoma in Situ -- Surgical Considerations in the Management of Primary Invasive Breast Cancer -- Sentinel Node Concept -- Breast Reconstructive Surgery -- The Role of Radiotherapy in Breast Cancer Management -- Adjuvant Systemic Therapy for Breast Cancer: An Overview -- Endocrine Therapy -- Chemotherapeutic Agents -- HER2-Targeted Therapy -- Inflammatory and Locally Advanced Breast Cancer -- Preoperative (Neoadjuvant) Systemic Therapy -- Metastatic Breast Cancer -- Hormone Replacement Therapy: A Critical Review -- Breast Diseases in Males -- Breast Cancer in the Elderly -- Breast Cancer in Younger Women -- Psychological Support for the Breast Cancer Patient -- Management of the Patient with a Genetic Predisposition for Breast Cancer -- Chemoprevention of Breast Cancer -- Design, Implementation, and Interpretation of Clinical Trials -- Structure of Breast Care Center -- Medicolegal Pitfalls in Breast Cancer Diagnosis and Management.
  • The risk of cancer increases with age and the number of older adults seeking treatment is rising dramatically in line with the aging population. The care of older patients differs from that of younger adults because of variation in the biology of the tumor, age-related variation in host physiology, co-morbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Management of Colorectal Cancers in Older People focuses on treatment strategies of colorectal cancers and provides guidance on the issues specific to older patients, spanning background and epidemiology, special considerations in the care of older people, therapeutics, and psychosocial considerations. This book offers a thorough review of current approaches to treating older colorectal cancer patients, detailing the special issues and considerations involved. The discipline-spanning coverage outlines best practice and proposes topics for future research. The third volume in the Management of Cancer in Older People series, this book will be of interest to all surgical oncologists, medical and radiation oncologists, gerontologists, proctologists and other members of the multidisciplinary team involved in the care of elderly colorectal cancer patients.
  • The risk of cancer increases with age and the number of older adults seeking treatment is rising dramatically in line with the aging population. The care of older patients differs from that of younger adults because of variation in the biology of the tumor, age-related variation in host physiology, co-morbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy.Management of Gynecological Cancers in Older Women focuses on treatment strategies of gynecological cancers and provides guidance on the issues specific to older patients, spanning background and epidemiology, special considerations in the care of older women, therapeutics, and psychosocial considerations. This book offers a thorough review of current approaches to treating older gynecological cancer patients, detailing the special issues and considerations involved. The discipline-spanning coverage outlines best practice and proposes topics for future research.The second volume in the Management of Cancer in Older People series, this book will be of interest to all surgical oncologists, medical oncologists, gerontologists, gynecologists and other members of the multidisciplinary team involved in the care of elderly gynecological cancer patients.
  • Epidemiology of Prostate Cancer in Europe /Ruben G. Cremers and Lambertus A. Kiemeney --Chemoprevention of Prostate Cancer /Bertrand Tombal --Individual and Mass Screening /Chris H. Bangma, Pim J. van Leeuwen and Monique J. Roobol --Anatomo-Pathology /Theodorus H. Van der Kwast --Biomarkers for Prostate Cancer /Gisele H. J. M. Leyten, Peter F. A. Mulders and Jack A. Schalken --Diagnosis, Clinical Work Up, TNM Classification, Markers /Jean-Luc Descotes and Anne-Sophie Gauchez --Active Surveillance for Favorable Risk Prostate Cancer: Background, Patient Selection, Triggers for Intervention, and Outcomes /Laurence Klotz --Open Radical Prostatectomy /Hein van Poppel and Steven Joniau --Robot-Assisted Radical Prostatectomy /Stefan Carlsson and Nils Peter Wiklund --Permanent Prostate Brachytherapy /Jan J. Battermann --High-Dose-Rate Brachytherapy: Indications, Technique, and Results /Alberto Bossi, Rodolfe Verstraet, Lucie Calmels and Pierre Blanchard.Intensity Modulated Radiotherapy for Prostate Cancer /Olivier Chapet, Corina Udrescu and Ciprian Enachescu --Combination of Androgen Deprivation Therapy and Radiation Therapy for Locally Advanced and Localized Prostate Cancer /Michel Bolla and Camille Verry --Postoperative Irradiation: Immediate or Early Delayed? /Dirk Bottke and Thomas Wiegel --High-Intensity Focused Ultrasound (HIFU) for Prostate Cancer /Albert Gelet, Sebastien Crouzet, Olivier Rouviere and Jean-Yves Chapelon --Cryotherapy /Matvey Tsivian and Thomas J. Polascik --Follow-up After Radical Treatments and Relapse /Nicolas Mottet --First-Line Hormonal Manipulation of Prostate Cancer /Suresh Venugopal and John Anderson --Resistance to Chemical Castration: Second-Line Hormonal Treatment /Yohann Loriot, Christophe Massard and Karim Fizazi --Targeted Therapies and Vaccination /Guru Sonpavde and Cora N. Sternberg --How to Interpret Results? /Laurence Collette --Management of Prostate Cancer: EAU Guidelines on Screening, Diagnosis and Treatment /Axel Heidenreich --Better Patients' Perspective /Louis J. Denis.
  • Epidemiology and risk factors / Ranko Miocinovic -- Twenty years and counting : is PSA still useful in 2010? / Haluk Ozen and Sertac Yazici -- Prostate cancer screening : a review of the evidence with clinical practice implications / Timothy J. Wilt -- Beyond PSA : promising new markers for prostate cancer / Leonard Marks -- Hereditary prostate cancer and genetic risk / Adam C. Reese, Graham Casey, and John S. Witte -- Prostate inflammation and prostate cancer / William G. Nelson ... [et al.] -- Molecular progression of prostate cancer : androgens and estrogens / Stephen A. Boorjian and Donald J. Tindall -- The role of obesity and diet in prostate cancer / Jean-Alfred Thomas II and Stephen J. Freedland -- Prostate cancer risk reduction by chemoprevention / Kenneth G. Nepple, Adam S. Kibel, and Gerald L. Andriole -- Current issues in pathologic evaluation / Sara M. Falzarano, Howard S. Levin, and Cristina Magi-Galluzzi -- Optimum prostate biopsy : techniques and strategies / Osama M. Zaytoun and J. Stephen Jones -- The utility of nomograms in routine clinical practice / Carvell T. Nguyen and Michael W. Kattan -- Active surveillance comes of age / Laurence Klotz -- Focal therapy : prostate hemiablation as the first historical treatment model for focal therapy of early stage prostate cancer / Vladimir Mouraviev and Thomas J. Polascik -- Contemporary external beam radiotherapy / Rahul Tendulkar and Kevin Stephans -- Surgery, brachytherapy, or external beam radiation for low- and intermediate-risk disease? / Jay P. Ciezki and Eric A. Klein -- The role for radical prostatectomy in advanced prostate cancer / R. Jeffrey Karnes and Michael L. Blute -- Radiation therapy in the management of locally advanced prostate cancer / Joseph D. Mancias and Anthony L. Zietman -- Clinical implications of measuring quality-of-life in early stage prostate cancer / Peter Chang, Mehrdad Alemozaffar, and Martin G. Sanda -- Treatment modalities of post-prostatectomy incontinence : a historical perspective as well as current therapy options / Christina Ching and Drogo K. Montague -- Management of biochemical recurrence after localized treatment for prostate cancer / Stephen B. Williams and Toni K. Choueiri -- Management of newly diagnosed metastatic disease / C. Lance Cowey and Thomas E. Hutson -- Pitfalls of androgen deprivation therapy / Alicia K. Morgans and Matthew R. Smith -- Current management of castration-resistant prostate cancer (CRPC) / Jorge A. Garcia and Robert Dreicer -- Beta-emitting radiopharmaceuticals and bone metastasis / Oliver Sartor.
  • Management of Soft Tissue Sarcoma addresses the diagnosis and best current management of adult soft tissue sarcomas. Edited by world renonwed experts, this book dileneates and discusses each different sarcoma subtype individually --source other than Library of Congress.
  • Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing. The book summarizes the high risk breast imaging options, including newest techniques and schedules. Pathologic evaluation of high risk lesions are featured as well as the management issues surrounding these lesions. The volume also covers the management of concomitant cancer risk and screening strategies.
  • Managing skin cancer 2010, Springer
    Diagnosis of Skin Cancer -- Histopathology of Skin Cancer -- Basal Cell Carcinoma -- Squamous Cell Carcinoma In Situ -- Invasive Squamous Cell Carcinoma of the Skin -- Cutaneous Malignant Melanoma -- Merkel Cell Carcinoma -- Cutaneous Lymphomas -- Kaposi Sarcoma -- Other Skin Cancers. Fibrohistiocytic Skin Cancers and Extramammary Paget's Disease -- Skin Cancer Under Special Circumstances -- Skin Cancer Prevention.
  • Chapter 1. Classification and Diagnosis of Anemia in Children -- Chapter 2. Anemia During the Neonatal Period -- Chapter 3. Iron-Deficiency Anemia -- Chapter 4. Megaloblastic Anemia -- Chapter 5. Hematologic Manifestations of Systemic Illness -- Chapter 6. Bone Marrow Failure -- Chapter 7. Red Cell Membrane and Enzyme Defects -- Chapter 8. Hemoglobinopathies -- Chapter 9. Extracorpuscular Hemolytic Anemia -- Chapter 10. Polycythemia -- Chapter 11. Disorders of White Blood Cells -- Chapter 12. Disorders of Platelets -- Chapter 13. Hemostatic Disorders -- Chapter 14. Thrombotic Disorders -- Chapter 15. Lymphadenopathy and Splenomegaly -- Chapter 16. Lymphoproliferative Disorders, Myelodysplastic Syndromes and Myeloproliferative Disorders -- Chapter 17. Leukemias -- Chapter 18. Histiocytosis Syndromes -- Chapter 19. Hodgkin Lymphoma -- Chapter 20. Non-Hodgkin Lymphoma -- Chapter 21. Central Nervous System Malignancies -- Chapter 22. Neuroblastoma -- Chapter 23. Renal Tumors -- Chapter 24. Rhabdomyosarcoma and Other Soft-Tissue Sarcomas -- Chapter 25. Malignant Bone Tumors -- Chapter 26. Retinoblastoma -- Chapter 27. Germ Cell Tumors -- Chapter 28. Hepatic Tumors -- Chapter 29. Hematopoietic Stem Cell Transplantation -- Chapter 30. Management of Oncologic Emergencies -- Chapter 31. Supportive Care of Patients with Cancer -- Chapter 32. Evaluation, Investigations and Management of Late Effects of Childhood Cancer -- Chapter 33. Psychosocial Aspects of Cancer for Children and their Families.
  • Cancer symptoms and side effects of treatment -- Cancer pain -- Cancer-related fatigue -- Palliative care: end-of-life symptoms -- Supportive care in elderly cancer patients -- Supportive care in pediatric oncology -- Quality-of-life assessment: the challenge of incorporating quality-of-life and patient-reported outcomes into investigative trials and clinical practice -- Cardiac toxicities of cancer therapies: challenges for patients and survivors of cancer -- Malignant pericardial effusion and cardiac tamponade (cardiac and pericardial symptoms) -- The vena cava syndrome -- Pulmonary toxicity of therapy -- Management of respiratory symptoms in people with cancer -- Endocrine and metabolic symptoms of cancer and its treatment -- Sexual problems in patients with cancer -- Sterility, infertility, and teratogenicity -- Menopause symptoms -- Preserving cardiac health in the breast cancer patient treated with anthracyclines -- Thrombosis and bleeding in cancer patients -- Lymphedema care -- Infections and cancer --Cancer cachexia and anorexia -- Xerostomia and dental problems in the head and neck radiation patient -- Dysphagia, reflux, and hiccups -- Nausea and vomiting -- Mucositis (oral and gastrointestinal) -- Diarrhea, constipation, and obstruction in cancer management -- Ascites -- Hepatotoxicity and hepatic dysfunction -- Urological symptoms and side effects of treatment -- Gynecological symptoms -- Central nervous system symptoms: headache, seizures, encephalopathy, and memory impairment -- Neuromuscular disease and spinal cord compression -- Eye symptoms and toxicities of systemic chemotherapy -- Extravasation -- Dermatologic toxicities -- Chemotherapy-induced alopecia: overview and methodology for characterizing hair changes and regrowth -- Rehabilitation in cancer -- Oral health and survivorship: late effects of cancer and cancer therapy -- Survivorship: psychosocial, physical issues, and insomnia -- Spiritual issues in supportive cancer care.
  • Mast cells and tumours 2011, Springer
  • Part I. Leukemia -- Chapter 1. Acute Lymphoblastic Leukemia -- Chapter 2. Adult Acute Myeloid Leukemia -- Chapter 3. Chronic Lymphocytic Leukemia and Associated Disorders -- Chapter 4. Chronic Myeloid Leukemia -- Chapter 5. Myelodysplastic Syndromes: The MD Anderson Cancer Center Approach -- Chapter 6. Philadelphia Chromosome-Negative Myeloproliferative Neoplasms -- Part II. Lymphoma and Myeloma -- Chapter 7. The Indolent Lymphomas -- Chapter 8. Aggressive and Highly Aggressive B-Cell Lymphomas -- Chapter 9. T-Cell Lymphomas -- Chapter 10. Hodgkin Lymphoma -- Chapter 11. Multiple Myeloma and Other Plasma Cell Dyscrasias -- Part III. Stem Cell Transplantation -- Chapter 12. Allogeneic Transplantation -- Chapter 13. Autologous Stem Cell Transplantation -- Part IV. Lung Cancer -- Chapter 14. Small Cell Carcinoma of the Lungs -- Chapter 15. Non-Small Cell Lung Cancer -- Part V. Head and Neck Cancer -- Chapter 16. Head and Neck Cancer -- Part VI. Gastrointestinal Carcinomas -- Chapter 17. Gastric and Esophageal Cancer -- Chapter 18. Pancreatic Cancer -- Chapter 19. Hepatobiliary Malignancies -- Chapter 20. Small Bowel Cancer and Appendiceal Tumors -- Chapter 21. Colorectal Cancer -- Chapter 22. Anal Cancer -- Chapter 23. Neuroendocrine Tumors -- Part VII. Breast Cancer -- Chapter 24. Early-Stage and Locally Advanced Breast Cancer -- Chapter 25. Metastatic Breast Cancer --Chapter 26. Inflammatory Breast Cancer -- Chapter 27. Special Situations in Breast Cancer -- Part VIII. Gynecologic Malignancies -- Chapter 28. Ovarian Cancer -- Chapter 29. Tumors of the Uterine Corpus -- Chapter 30. Tumors of the Uterine Cervix -- Chapter 31. Gestational Trophoblastic Tumors -- Part IX. Genitourinary Carcinoma -- Chapter 32. Renal Cell Carcinoma -- Chapter 33. Bladder Cancer -- Chapter 34. Prostate Cancer -- Chapter 35. Penile Cancer -- Chapter 36. Germ Cell Tumors -- Part X. Miscellaneous Tumors -- Chapter 37. Tumors of the Central Nervous System -- Chapter 38. Endocrine Malignancies -- Chapter 39. Malignant Melanoma -- Chapter 40. Soft Tissue and Bone Sarcomas -- Chapter 41. The AIDS-Related Cancers -- Chapter 42. Carcinoma of Unknown Primary -- Part XI. Supportive Care -- Chapter 43. Infection in the Neutropenic Patient -- Chapter 44. Fungal and Viral Infections in Cancer Patients -- Chapter 45. Endocrine and Metabolic Complications of Cancer Therapy -- Chapter 46. Oncologic Emergencies -- Part XII. Palliative Care and Symptom Management -- Chapter 47. Defining Palliative Care in Oncology -- Chapter 48. Pain Management and Symptom Control -- Part XIII. Long-Term Survival -- Chapter 49. Pediatric Long-Term Follow-Up -- Chapter 50. Adult Long-Term Follow-Up -- Chapter 51. Rehabilitation.
  • "The current edition of The Handbook provides an overview of current care of patients with cancer diagnoses commonly evaluated and treated by surgical oncologists, and in doing so continues to align such care with the underlying philosophy of the Department of Surgical Oncology at M.D. Anderson: multidisciplinary, cooperative care is the ideal way to manage patients with cancer. Such care begins with an understanding of the underlying tumor biology and natural history of the disease and includes technical excellence in the delivery of indicated surgical treatment. It also demands integration of essential information from the available literature on currently preferred treatment modalities, and emphasizes appropriate inclusion of adjunctive specialty care, including medical oncology, radiation oncology, interventional radiology, palliative care, pain management, physical therapy, nutritional support, social services and nursing"--Provided by publisher.
  • Melanoma development 2011, Springer
  • Manufacturing of microarrays -- Technological platforms for microarray gene expression profiling -- Principles of gene microarray data analysis -- Gaining weights ... and feeling good about it! -- Complementary techniques -- Microarrays for cancer diagnosis and classification -- Gene profiling for the prediction of tumor response to treatment: the case of immunotherapy -- Identification of molecular determinants of tumor sensitivity and resistance to anticancer drugs -- SNP and mutation analysis -- Cancer development and progression -- Gene expression profiling in malignant lymphomas -- Tumor immunology.
  • Micrometastasis 2003, Springer
  • MicroRNA and Cancer 2011, Springer Protocols
    MicroRNA Biogenesis and Cancer / Julia Winter, Sven Diederichs -- Computational Identification of miRNAs Involved in Cancer / Anastasis Oulas, Nestoras Karathanasis, Panayiota Poirazi -- The Principles of MiRNA-Masking Antisense Oligonucleotides Technology / Zhiguo Wang -- The Concept of Multiple-Target Anti-miRNA Antisense Oligonucleotide Technology / Zhiguo Wang -- Modulation of MicroRNAs for Potential Cancer Therapeutics / Wei Wu -- Detection of MicroRNAs in Cultured Cells and Paraffin-Embedded Tissue Specimens by In Situ Hybridization / Ashim Gupta, Yin-Yuan Mo -- MicroRNA Northern Blotting, Precursor Cloning, and Ago2-Improved RNA Interference / Julia Winter, Sven Diederichs -- miRNA Profiling on High-Throughput OpenArray System / Elena V. Grigorenko, Elen Ortenberg, James Hurley, Andrew Bond, Kevin Munnelly -- Silicon Nanowire Biosensor for Ultrasensitive and Label-Free Direct Detection of miRNAs / Guo-Jun Zhang -- High-Throughput and Reliable Protocols for Animal MicroRNA Library Cloning / Caide Xiao -- MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer Cells / Keith M. Giles, Andrew Barker, Priscilla M. Zhang, Michael R. Epis, Peter J. Leedman -- Epigenetic Regulation of MicroRNA Expression in Cancer / Hani Choudhry, James W. Catto -- In Vitro Functional Study of miR-126 in Leukemia / Zejuan Li, Jianjun Chen -- Prediction of the Biological Effect of Polymorphisms Within MicroRNA Binding Sites / Debora Landi, Roberto Barale, Federica Gemignani, Stefano Landi -- The Guideline of the Design and Validation of MiRNA Mimics / Zhiguo Wang -- Analysis of Targets and Functions Coregulated by MicroRNAs / Shu-Jen Chen, Hua-Chien Chen -- Utilization of SSCprofiler to Predict a New miRNA Gene / Anastasis Oulas, Panayiota Poirazi -- MicroRNA Profiling Using Fluorescence-Labeled Beads: Data Acquisition and Processing / Thomas Streichert, Benjamin Otto, Ulrich Lehmann.
  • MicroRNA in cancer 2013, Springer
  • Measurement and interpretation of microRNA expression profiles / Bo Curry and Robert Ach -- MicroRNA expression analysis by LNA enhanced microarrays / Rolf Sokilde ... [et al.] -- Analysis and QC for real-time OPCR arrays of human microRNAs / Dirk P. Ditmer ... [et al.] -- Massively parallel microRNA profiling in the haematologic malignancies / Ryan D. Morin ... [et al.] -- Who dunit? microRNAs involved in prostate cancer / Chang Hee Kim -- Intronic microRNA : creation, evolution and regulation / Sailen Barik and Titus Barik -- miRome architechture and genomic instability / Konrad Huppi ... [et al.] -- Interconnection of microRNA and transcription factor-mediated regulatory networks / Yiming Zhou -- Analysis of microRNA profiling data with systems biology tools / Yuriy Gusev ... [et al.] -- Mathematical and computational modeling of post-transriptional gene regulation by microRNAs / Raya Khanin and Desmond J. Higham.
  • Part 1.Introduction --Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer: Open Questions for Research /Michail Ignatiadis, Christos Sotiriou and Klaus Pantel --Part 2.Minimal residual disease and breast cancer metastasis --Self-Seeding in Cancer /Elizabeth Comen and Larry Norton --Microenvironments Dictating Tumor Cell Dormancy /Paloma Bragado, Maria Soledad Sosa, Patricia Keely, John Condeelis and Julio A. Aguirre-Ghiso --Part 3.Technologies for circulating tumor cell (CTC) and disseminated tumor cell (DTC) detection and characterization --Immunomagnetic Separation Technologies /Astrid E. L. M. Hoeppener, Joost F. Swennenhuis and Leon W. M. M. Terstappen --Microfluidic Technologies /Ali Asgar. S. Bhagat and Chwee Teck Lim --EPISPOT Assay: Detection of Viable DTCs/CTCs in Solid Tumor Patients /Catherine Alix-Panabières --Advances in Optical Technologies for Rare Cell Detection and Characterization /Lou Dietz and Richard Bruce --Size-Based Enrichment Technologies for CTC Detection and Characterization /Anthony Williams, Marija Balic, Ram Datar and Richard Cote --Emerging Technologies for CTC Detection Based on Depletion of Normal Cells /Maryam Lustberg, Kris R. Jatana, Maciej Zborowski and Jeffrey J. Chalmers --Molecular Assays for the Detection and Characterization of CTCs /Evi S. Lianidou and Athina Markou --Multiplex Molecular Analysis of CTCs /Anieta M. Sieuwerts and Stefanie S. Jeffrey.Part 4.Other blood-based biomarkers /Circulating DNA and Next-Generation Sequencing --Susanna Cooke and Peter Campbell --Circulating MicroRNAs as Noninvasive Biomarkers in Breast Cancer /Maria Angelica Cortez, James William Welsh and George Adrian Calin --Circulating Endothelial Cells and Circulating Endothelial Progenitors /Patrizia Mancuso, Angelica Calleri and Francesco Bertolini --Part 5.Disseminated tumor cells (DTCs) and circulating tumor cells (CTCs) in breast cancer clinical research and practice --DTCs in Breast Cancer: Clinical Research and Practice /W. Janni, Brigitte Rack, N. Kasprowicz, C. Scholz and P. Hepp --CTCs in Primary Breast Cancer (I) /Brigitte Rack, Ulrich Andergassen, Wolfgang Janni and Julia Neugebauer --CTCs in Primary Breast Cancer (II) /E. Saloustros and D. Mavroudis --CTCs in Metastatic Breast Cancer /Antonio Giordano and Massimo Cristofanilli --HER2-Positive DTCs/CTCs in Breast Cancer /Andreas D. Hartkopf, Malgorzata Banys and Tanja Fehm --DTCs/CTCs in Breast Cancer: Five Decades Later /Susan Alsamarai, Maysa M. Abu-Khalaf and Lyndsay N. Harris --Part 6.Drug and circulating tumor cell co-development --Challenges in Drug and Biomarker Co-Development /Sheila E. Taube and Tracy Lively --Challenges and Opportunities in the Use of CTCs for Companion Diagnostic Development /Elizabeth A. Punnoose and Mark R. Lackner.
  • Mitochondria and cancer 2009, Springer
  • Malignant tumors due to breast cancer and masses due to benign disease appear in mammograms with different shape characteristics: the former usually have rough, spiculated, or microlobulated contours, whereas the latter commonly have smooth, round, oval, or macrolobulated contours. Features that characterize shape roughness and complexity can assist in distinguishing between malignant tumors and benign masses. In spite of the established importance of shape factors in the analysis of breast tumors and masses, difficulties exist in obtaining accurate and artifact-free boundaries of the related regions from mammograms. Whereas manually drawn contours could contain artifacts related to hand tremor and are subject to intra-observer and inter-observer variations, automatically detected contours could contain noise and inaccuracies due to limitations or errors in the procedures for the detection and segmentation of the related regions. Modeling procedures are desired to eliminate the artifacts in a given contour, while preserving the important and significant details present in the contour.
  • Modern molecular biology 2010, Springer
    Genome-Scale Analysis of Data from High-Throughput Technologies / Sarah J. Wheelan -- Analysis of Inherited and Acquired Genetic Variation / Srinivasan Yegnasubramanian and William B. Isaacs -- Examining DNA-Protein Interactions with Genome-Wide Chromatin Immunoprecipitation Analysis / Esteban Ballestar and Manel Esteller -- Genome-Wide DNA Methylation Analysis in Cancer Research / Srinivasan Yegnasubramanian and William G. Nelson -- Use of Expression Microarrays in Cancer Research / Jun Luo and Yidong Chen -- Signal Sequencing for Gene Expression Profiling / Biaoyang Lin, Jeremy Wechsler and Leroy Hood -- Mass Spectrometry Based Proteomics in Cancer Research / Mohamad A. Abbani, Parag Mallick and Maryann S. Vogelsang -- Tissue Microarrays in Cancer Research / Toby C. Cornish and Angelo M. De Marzo.
  • An Introduction to Mohs Micrographic Surgery --Indications for Mohs Micrographic Surgery --Preoperative Evaluation --Mohs Micrographic Surgery Operative Room Setup --Anesthetic Considerations: Local Versus Regional --Cutaneous Anatomy in Mohs Micrographic Surgery --Mohs Surgery: Fixed Tissue Technique --Fresh Tissue Technique --Special Considerations for Mohs Micrographic Surgery in Organ Transplant Recipients --Mohs Micrographic Surgery in Ethnic Skin --Histopathology Laboratory Setup and Necessary Instrumentation --Tissue Transport and Initial Processing Cryostat Preparation of Slides --Histopathologic Interpretation of Mohs Slides --Tissue Specimen Documentation, Record Keeping, and Sample Storage --Immunostains --Basal Cell Carcinoma --Squamous Cell Carcinoma --Mohs Micrographic Surgery for the Treatment of Cutaneous Melanoma --Dermatofibrosarcoma Protuberans --Microcystic Adnexal Carcinoma --Atypical Fibroxanthoma --Extramammary Paget Disease --Leiomyosarcoma --Merkel Cell Carcinoma --Selected Sweat Gland Carcinomas --Sebaceous Carcinoma --Mohs Micrographic Surgery for the Eyelid --Mohs Surgery for Periungual and Subungual Skin Cancer --Genitalia --Deep Structures of the Head and Neck --Complications of Mohs Micrographic Surgery --Eyelid Reconstruction After Mohs Micrographic Surgery --Flaps --Skin Grafting --Side to Side Closure After Mohs Surgery --Prosthetic Rehabilitation --Combination Therapy for the Nonsurgical Treatment of Skin Cancers: Latest Research at Mount Sinai --Training and Regulation in Mohs Surgery --Establishing a Mohs Practice --International Perspective of Mohs Micrographic Surgery: South America --International Perspective of Mohs Micrographic Surgery: Europe --International Perspective of Mohs Micrographic Surgery: East Asia --International Perspective of Mohs Micrographic Surgery: Australia and New Zealand --Information for Patients and Safety Considerations --Ethical Issues Related to Mohs Skin Cancer Surgery --Medicolegal Issues Regarding Mohs Micrographic Surgery --Psychological Issues Regarding Mohs Micrographic Surgery.
  • Molecular approaches to controlling cancer 2005, Cold Spring Harb Lab Press
    Cancer genetics and genomes -- DNA damage response -- Cancer biology and stem cells -- Telomeres, senescence, and aging -- Animal models for cancer -- Gene expression and cancer -- Tumor responses to microenvironment -- Angiogenesis -- Discovering cancer targets -- Therapeutic approaches.
  • Part 1.Molecular Biology of Selected Hemato-oncologic Diseases --Molecular Biology of Acute Lymphoblastic Leukemia /Małgorzata Dawidowska, Monika D. Kraszewska, Katarzyna Derwich and Tomasz Szczepański --Genetic Mechanisms and Molecular Markers of Neoplastic Transformation in Acute Myeloid Leukemia /Agata A. Filip, Marta Libura, Sebastian Giebel and Olga Haus --Molecular Pathogenesis of Aggressive B-cell Lymphomas /Przemysław Juszczyński and Krzysztof Warzocha --Molecular Biology and Classification of Multiple Myeloma /Anna Dmoszyńska and Norbert Grząśko --Chronic Lymphocytic Leukemia /Anton W. Langerak and Yorick Sandberg --Molecular Biology of Chronic Myeloid Leukemia /Tomasz Sacha, Kajetana Foryciarz and Aleksander B. Skotnicki --Molecular Biology of Myelodysplastic Syndromes /Francesc Solé --Myeloproliferative Neoplasms /Andrzej Hellmann, Maria Bieniaszewska, Witold Prejzner and Aleksandra Leszczyńska --Part 2.Diagnostics and Monitoring of Therapy of Hemato-oncologic Deseases --Flow Cytometric Immunophenotyping as Diagnostic Tool of Hematopoietic Malignancies /Łukasz Sędek, Juan Flores-Montero, Joanna Bulsa, Susana Barrena and Julia Almeida, et al. --Cytogenetics in Hematology /Olga Haus, Anna Poluha and Katarzyna Skonieczka --Monitoring of Minimal Residual Disease in Acute Lymphoblastic Leukemia /Tomasz Szczepański, Małgorzata Dawidowska and Katarzyna Derwich --Gene Expression Profiling in Hematologic Malignancies /Przemysław Juszczyński, Bjoern Chapuy, Małgorzata Szczepaniak and Krzysztof Warzocha --Part 3.Molecular Procedures Involved in Hematopoietic Stem Cell Transplantation --Allogeneic Transplantation of Hematopoietic Stem Cells /Jacek Wachowiak --Genetic Basis of Donor-Recipient Matching in Allogeneic Transplantation of Hematopoietic Stem Cells /Jacek Nowak and Jacek Wachowiak --Chimerism Following Allogeneic Transplantation of Hematopoietic Stem Cells /Małgorzata Dawidowska, Katarzyna Guz, Ewa Brojer, Jacek Wachowiak and Michał Witt --Peritransplantation Monitoring of Minimal Residual Disease in Acute Lymphoblastic Leukemia /Małgorzata Dawidowska, Katarzyna Derwich and Tomasz Szczepański --Biobanks of Cellular Material /Wiesław Wiktor-Jędrzejczak and Elżbieta Urbanowska --Part 4.Molecular Diagnostic Protocols --Biobanking of Cellular Material /Anna Poluha and Elżbieta Urbanowska --Isolation of Mononuclear Cells from Human Blood and Bone Marrow by Density Gradient Centrifugation /Małgorzata Dawidowska --Molecular Techniques Commonly Used in Hemato-oncology /Monika D. Kraszewska and Ewa Ziętkiewicz --Genetic Methods of HLA Typing /Jacek Nowak, Renata Mika-Witkowska and Elżbieta Graczyk-Pol --Post-Transplant Chimerism Analysis Through STR-PCR and RQ-PCR /Małgorzata Dawidowska, Katarzyna Guz, Agnieszka Orzińska, Justyna Smolarczyk-Wodzyńska and Monika D. Kraszewska, et al. --Analysis of Minimal Residual Disease with the Use of Rearrangements of Ig/TCR Genes Through RQ-PCR /Małgorzata Dawidowska, Vincent H. J. van der Velden, Michał Witt and Tomasz Szczepański --Molecular Diagnostics of Acute Myeloblastic Leukemia /Marta Libura, Agata A. Filip and Olga Haus --Assessment of the Presence and the Level of BCR-ABL Fusion Gene Expression and Mutational Status in ABL Kinase Domain /Sylwia Czekalska, Magdalena Zawada and Izabela Florek --Studies of Rearrangements and Somatic Hypermutation of IGHV Genes in Chronic Lymphocytic Leukemia /Anton W. Langerak, Richard Rosenquist, Paolo Ghia, Chrysoula Belessi and Kostas Stamatopoulos, et al. --Molecular Biology Methods in the Diagnosis of Multiple Myeloma /Anna Dmoszyńska and Sylwia Chocholska --Molecular Methods in Myeloproliferative Neoplasms /Aleksandra Leszczyńska, Witold Prejzner, Maria Bieniaszewska and Andrzej Hellmann --Informed Consent for Participation in Research Project /Małgorzata Dawidowska and Michał Witt.
  • Carcinogens and mutagens -- Whole animal carcinogenicity bioassays -- Molecular mechanisms of action of selected organic carcinogens -- Binding of carinogens to DNA and covalent adducts and DNA damage - PAH, aromatic amines, nitro-aromatic compounds, and halogenated compounds -- Cellular oncogenes and carcinogenesis -- Tumor suppressor genes -- Hepatitis B, Hepatitis C, and hepatocellular carcinoma -- Oncongenesis in transgenic and knockout mice -- Chemically induced morphological and neoplastic transformation in C3H/10T1/2 C1 8 mouse embryo cells -- Radiation carcinogenesis -- DNA microarrays and computational analysis of DNA microarray data in cancer research -- Application of proteomics in basic biological sciences and cancer -- Overview of human cancer induction and human exposure to carcinogens -- Complex mixtures of chemical carcinogens: principles of action and human cancer -- Lung cancer -- Breast cancer -- Cancer of the prostate - Mechanisms of molecular carcinogenesis -- Skin cancer: epidemiology, clinical manifestations, and genetic and molecular aspects -- Cell and molecular biology of cancer of the brain --Thyroid cancer: molecular biology and clinical aspects -- Chemoprevention of chemical carcinogenesis and human cancer -- Carcinogen biomarkers and exposure assessment -- Risk assessment for chemical carcinogens -- Prevention and regulation approaches to carcinogens.
  • Molecular diagnosis of cancer. 2nd ed. 2004, Springer Protocols
  • Molecular diagnostics 2010, CRCnetBASE
  • 1. Brain tumors -- 2. Immunophenotypic characterizaton of infiltrating poly- and mononuclear cells in childhood brain tumors -- 3. Experimental therapies in brain tumors -- 4. Biologic anti-neoplastic therapies -- 5. The lymphokine activated killer (LAK) cell phenomenon -- 6. Angiogenesis inhibition in anti-neoplastic therapy -- 7. Antigen presentation by dendritic cells and their significance in anti-neoplastic immunotherapy -- 8. Genetically engineered antibodies for direct anti-neoplastic treatment and systematic delivery of various therapeutic agents to cancer cells -- 9. Cancer-testis antigens: promising targets for antigen directed anti-neoplastic immunotherapy -- 10. Materials and methods -- 11. Index.
  • The epidemiology of basal cell and squamous cell carcinoma / Hao Wang and Thomas L. Diepgen -- Histology of epithelial skin tumors / Jörg Reichrath and Kerstin Querings -- UV damage and DNA repair in basal cell and squamous cell carcinomas / Knuth Rass -- Papillomavirus infections and cancerogenesis of squamous cell and basal cell carcinomas / Guido Bens -- The immune system and nonmelanoma skin cancers / Elma D. Baron -- Cytogenetics of basal cell carcinoma and squamous cell carcinomas / Melanie A. Carless, Kevin J. Ashton and Lyn R. Griffiths -- The hedgehog signaling pathway and epithelial skin cancer / Julia Reifenberger -- p53 protein and nonmelanoma skin cancer / Vladislava O. Melnikova and Honnavara N. Ananthaswamy -- TGF-[beta] pathway and cancerogenesis of epithelial skin tumors / Miguel Quintanilla ... [et al.] -- PDGF pathways and growth of basal cell and squamous cell carcinomas / Jingwu Xie -- Apoptosis and cancerogenesis of basal cell and squamous cell carcinoma / Peter Erb ... [et al.] -- The role of telomerase for cancerogenesis of basal cell and squamous cell carcinomas / Eva-Maria Fabricius.
  • Theories of carcinogenesis -- Physioloigic correlates of malignancy -- Cell division and survival -- Cellular senescence -- Invasiveness -- DNA repair -- Epigenetic regulation of cancer-associated gene products -- Interaction of the groups of cancer-related gene products -- Structural growth control -- The organ preference of metastasis formation -- Angiogenesis -- Interactions with the immune system -- Endocrine dysregulation -- Dormancy and minimal residual disease -- Epithelial tumors -- Hematologic malignancies -- Mesenchymal tumors -- Neurologic tumors -- Tumors of serous cavities -- Embryonic tumors.
  • Section I. Molecular Pathology of Hematolymphoid Neoplasms: General Principles -- Molecular Oncogenesis / Aniruddha J. Deshpande, Christian Buske, Leticia Quintanilla-Martinez, and Falko Fend -- Genetic Predispositions for Hematologic and Lymphoid Disorders / Frederick G. Behm -- Prognostic Markers / David Bahler -- Cancer Stem Cells: Potential Targets for Molecular Medicine / Isabel G. Newton and Catriona H.M. Jamieson -- Gene Therapy for Leukemia and Lymphoma / Xiaopei Huang and Yiping Yang -- Chemical and Environmental Agents (Including Chemotherapeutic Agents and Immunosuppression) / Richard J.Q. McNally -- Viral Oncogenesis / Alexander A. Benders and Margaret L. Gulley -- Section II. Specific Techniques and Their Applications in Molecular Hematopathology -- Techniques to Determine Clonality in Hematolymphoid Malignancies / Daniel E. Sabath -- Techniques to Detect Defining Chromosomal Translocations/Abnormalities / Jennifer J.D. Morrissette, Karen Weck, and Cherie H. Dunphy -- Molecular Techniques to Detect Disease and Response to Therapy: Minimal Residual Disease / Marie E. Beckner and Jeffrey A. Kant -- Detection of Resistance to Therapy in Hematolymphoid Neoplasms / Karen Weck -- Monitoring Engraftment of Bone Marrow Transplant by DNA Fingerprinting / Jessica K. Booker -- Gene Expression Profiling / Cherie H. Dunphy -- Proteomics of Human Malignant Lymphoma / Megan S. Lim, Rodney R. Miles, and Kojo S.J. Elenitoba-Johnson -- Mouse Models of Hematolymphoid Malignancies / Krista M.D. La Perle and Suzana S. Couto -- Section III. Molecular Pathology of Hematolymphoid Neoplasms: Specific Subtypes -- Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma / Patricia Aoun -- Marginal Zone B-Cell Lymphoma / Lynne V. Abruzzo and Rachel L. Sargent -- Lymphoplasmacytic Lymphoma / Pei Lin -- Molecular Pathology of Plasma Cell Neoplasms / James R. Cook -- The Roles of Molecular Techniques in the Diagnosis and Management of Follicular Lymphoma / W. Richard Burack -- Mantle Cell Lymphoma / Kai Fu and Qinglong Hu -- Diffuse Large B-Cell Lymphomas / Cherie H. Dunphy --The Molecular Pathology of Burkitt Lymphoma / Claudio Mosse and Karen Weck -- Precursor B-Cell Acute Lymphoblastic Leukemia / Julie M. Gastier-Foster -- Molecular Genetics of Mature T/NK Neoplasms / John P. Greer, Utpal P. Davé, Nishitha Reddy, Christine M. Lovly, and Claudio A. Mosse -- Precursor T-Cell Neoplasms / Kim De Keersmaecker and Adolfo Ferrando -- Classical Hodgkin Lymphoma and Nodular Lymphocyte-Predominant Hodgkin Lymphoma / Michele Roullet and Adam Bagg -- Posttransplant Lymphoproliferative Disorder / Margaret L. Gulley -- AIDS-Related Lymphomas / Amy Chadburn and Ethel Cesarman -- Chronic Myelogenous Leukemia / Dan Jones -- Molecular Pathogenesis of Nonchronic Myeloid Leukemia Myeloproliferative Neoplasms / Mike Perez and Chung-Che (Jeff) Chang -- Molecular Pathology of Myelodysplastic/Myeloproliferative Neoplasms, Myeloid, and Lymphoid Neoplasms with Eosinophilia and Abnormalities of PDGFRA, PDGFRB, and FGFR1, and Mastocytosis / Robert P. Hasserjian -- Molecular Pathogenesis of Myelodysplastic Syndromes / Jesalyn J. Taylor and Chung-Che "Jeff" Chang -- Acute Myeloid Leukemias with Recurrent Cytogenetic Abnormalities / Sergej Konoplev and Carlos Bueso-Ramos -- Acute Myeloid Leukemias with Normal Cytogenetics / Sergej Konoplev and Carlos Bueso-Ramos -- Acute Myeloid Leukemia with Myelodysplasia-Related Changes and Therapy-Related Acute Myeloid Leukemia / Sergej N. Konoplev and Carlos E. Bueso-Ramos -- Molecular Pathology of Hemoglobin and Erythrocyte Membrane Disorders / Murat O. Arcasoy and Patrick G. Gallagher -- White Blood Cell and Immunodeficiency Disorders / John F. Bastian and Michelle Hernandez -- Molecular Basis of Disorders of Hemostasis and Thrombosis / Alice Ma -- Sarcoidosis: Are There Sarcoidosis Genes? / Helmut H. Popper -- Castleman's Disease / Richard Flavin, Cara M. Martin, Orla Sheils, and John James O'Leary -- Molecular Pathology of Histiocytic Disorders / Mihaela Onciu -- Reactive Lymphadenopathies: Molecular Analysis / Dennis P. O'Malley -- Molecular Pathology of Infectious Lymphadenitides / Kristin Fiebelkorn -- Gene Therapy for Nonneoplastic Hematologic and Histiocytic Disorders / Kareem N. Washington, John F. Tisdale, and Matthew M. Hsieh.
  • Introduction -- Mechanisms of Gastrointestinal Carcinogenesis /Frank I. Scott, John P. Lynch -- Epithelial Neoplastic Disease -- Targeted Therapies and Molecular Diagnostics of Gastrointestinal Cancers /Davendra Sohal, Antonia R. Sepulveda, Weijing Sun -- Molecular Pathology of Barrett's Metaplasia and Esophageal Adenocarcinoma /Mamoun Younes -- Molecular Pathology of Squamous Carcinomas of the Esophagus /Rohinton S. Tarapore, Jonathan P. Katz -- Molecular Mechanisms and Pathology of Gastric Carcinogenesis: Sporadic Cancers /Shuko Harada, Antonia R. Sepulveda -- Hereditary Diffuse Gastric Cancer and Other Gastric Cancers Associated with Hereditary Predisposition Syndromes /Fátima Carneiro, Carla Oliveira, Raquel Seruca -- Cancer Predisposition Syndromes of the Gastrointestinal Tract /Ian S. Hagemann, Antonia R. Sepulveda -- Molecular Pathology of Colon and Small Bowel Cancers: Sporadic Type /Asif Rashid -- Cancers of the Rectum and Anal Canal /Jenia Jenab-Wolcott, Bruce Giantonio -- Molecular Pathology of Inflammatory Bowel Disease-Associated Neoplasia /Takeshi Uehara, Deqin Ma, Antonia R. Sepulveda -- Non-Epithelial Neoplastic Tumors -- Molecular Biology and Pathology of Gastrointestinal Stromal Tumors /Paul J. Zhang -- Neuroendocrine Tumors /Joseph R. Pisegna -- Metastatic Disease and Tumor Markers -- Molecular Mechanisms of Tumor Metastasis /Andrew D. Rhim, Davendra Sohal, Hiroshi Nakagawa -- Circulating Tumor Cells and Nucleic Acids for Tumor Diagnosis /Loren Joseph -- Serological Markers of Digestive Tract Cancers /Jorge L. Sepulveda.
  • Pituitary tumor classification : functionality, invasiveness, and aggressiveness -- Immunohistochemistry and electron microscopy as evaluation criteria in tumor classification in the deciphering of pituitary adenomas -- Proliferation -- Angiogenesis -- Apoptosis -- Signal transduction -- Stem cell markers in pituitary adenomas -- MicroRNAs -- New generic tools for diagnosis: genomics and proteomics -- Therapeutic approaches: drug, surgical, and radiotherapy.
  • Part 1. Hematologic Malignancies -- The Emerging Era of Targeted Therapy in Childhood Acute Lymphoblastic Leukemia / William L. Carroll and Rob Pieters -- Molecular Targeted Therapies in T-Cell Acute Lymphoblastic Leukemia / Alejandro Gutierrez and A. Thomas Look -- Molecularly Targeted Therapy for Infant ALL / Patrick A. Brown and Carolyn A. Felix -- Targeted Therapeutic Approaches for AML / Robert J. Arceci and Donald Small -- Acute Promyelocytic Leukaemia / Andrea Biondi, Anna Maria Testi and Brenda E. S. Gibson -- Down Syndrome and Acute Myeloid Leukemia: An Unique Genetic Sensitivity to Chemotherapy / Jeffrey W. Taub, Yubin Ge and Yaddanapudi Ravindranath -- Targeting RAS Signaling Pathways in Juvenile Myelomonocytic Leukemia (JMML) / Jennifer O'Hara Lauchle and Benjamin S. Braun -- Chronic Myeloid Leukemia: Pathophysiology and Therapeutics / Seth J. Corey and Jorge Cortes -- Molecularly Targeted Therapies in Pediatric Myelodysplastic Syndromes / Lia Gore -- New Therapeutic Frontiers for Childhood Non-Hodgkin Lymphoma / Megan S. Lim and Mitchell S. Cairo -- Molecular Targeting of Post-transplant Lymphoproliferative Disorders / Michael Wang and Thomas G. Gross -- Part 2. Solid Tumors -- Molecularly Targeted Therapies for Astrocytomas / Ian F. Pollack -- Targeted Therapy in Medulloblastoma in Molecularly Targeted Therapy for Childhood Cancer / Yoon-Jae Cho and Scott L. Pomeroy -- Future Treatments of Ependymoma / Richard J. Gilbertson -- Development of Targeted Therapies for Rhabdoid Tumors Based on the Functions of INI1/hSNF5 Tumor Suppressor / Ganjam V. Kalpana and Melissa E. Smith -- Development of Targeted Therapies for Neurofibromatosis Type 1 (NF1) Related Tumors / Brigitte Widemann -- Molecular Therapy for Neuroblastoma / Yaël P. Mossé and John M. Maris -- Ewing's Sarcoma Family of Tumors: Molecular Targets Need Arrows / Jeffrey A. Toretsky and Aykut Üren -- Molecular Targeted Therapy for Wilms' Tumor / James I. Geller and Jeffrey S. Dome -- Molecular Therapy for Rhabdomyosarcoma / Raushan T. Kurmasheva, Hajime Hosoi, Ken Kikuchi and Peter J. Houghton -- Molecularly Targeted Therapy for Osteosarcoma: Where Do We Go from Here? / Rosanna Ricafort and Richard Gorlick -- Nonrhabdomyosarcoma Soft Tissue Sarcoma in Children: Developing New Treatments Based on a Better Understanding of Disease Biology / Stephen X. Skapek.
  • Mortalin biology 2012, Springer
    Part 1.Structure and Function of Mortalin /Birth of Mortalin: Multiple Names, Niches and Functions Connecting Stress, Senescence and Cancer /Renu Wadhwa and Sunil C. Kaul --Mortalin's Machinery /Custer C. Deocaris, Sunil C. Kaul and Renu Wadhwa --The Role of Mortalin in Iron Homeostasis /Wen-I Luo and James A. Cowan --Functional Characteristics of Mortalin /Walter A. Baseler, Tara L. Croston and John M. Hollander --Part 2.Mortalin in Evolution2 Deocaris /Mortalin and Drosophila DmHsp22: Two Mitochondrial Chaperones Regulating Aging and Carcinogenesis /Marie Le Pécheur, Geneviève Morrow and Robert M. Tanguay --Mortalin in Invertebrates and The Induction of Apoptosis by Wild-Type p53 Following Defeat of Mortalin-Based Cytoplasmic Sequestration in Cancerous Clam Hemocytes /Charles W. Walker, Ben Low and S. Anne Böttger --Mortalin and Stem Cells: A Study from Planarians /Renata Batistoni --Part 3.Mortalin in Health and Disease /Mortalin in Cell Protection from Immune Attack /Moran Saar, Oren Moskovich and Zvi Fishelson --Mortalin in Neurological Diseases /Jinghua Jin, Jing Zhang, Travis J. Cook and Jake G. Hoekstra --Loss of Mortalin Function in Parkinson's Disease-Supporting the Mitochondrial Pathway of Neurodegeneration /Lena F. Burbulla and Rejko Krüger --Hsp75/mortalin and Protection from Ischemic Brain Injury /Robin E. White, Yi-Bing Ouyang and Rona G. Giffard --Catecholamine Regulated Protein (CRP40), A Splice Variant of Mortalin-2: Functional Role in CNS Disorders /Joseph P. Gabriele, Sarah E. Groleau, Ritesh P. Daya, Zdenek B. Pristupa and Ram K. Mishra --Chaperonopathies: Diseases in Which Mortalin and Other Hsp-Chaperones Play a Role in Etiology and Pathogenesis /Alberto J. L. Macario, Francesco Cappello and Everly Conway de Macario --Part 4.Mortalin and Cancer /Many Faces of Mortalin and Tid1 /Ohad Iosefson and Abdussalam Azem --Mortalin: A Positive Regulator of Centrosome Duplication and Amplification /Masayuki Kanai and Kenji Fukasawa --Mortalin Expression in Normal and Neoplastic Tissues /Angheliki Nomikos, Sinclair R. Dundas and Graeme I. Murray --Mortalin-p53 Interaction as a Target for Liver Cancer Therapy /Wen-Jing Lu, Nikki P. Lee, Renu Wadhwa and John M. Luk --Mortalin Targeting Gadgets for Cancer Therapy /Chae-Ok Yun and Renu Wadhwa --Part 5.Mortalin Based Technologies /Cell Internalizing Anti-Mortalin Antibody for Generation of Illuminating MSCs for Long-Term In vitro and In vivo Tracking /Toshimasa Uemura, Masanori Nishi, Sunil C. Kaul and Renu Wadhwa --Mortalin Staining Pattern as a Reporter for Cell Based Anti-Cancer Drug Screening /Ran Gao, Zeenia Kaul, Tomoko Yaguchi and Renu Wadhwa --Cell Internalizing Anti-mortalin Antibody as a Nanocarrier /Zeenia Kaul, Tomoko Yaguchi, Renu Wadhwa and Sunil C. Kaul.
  • MRI of rectal cancer 2010, Springer
  • mTORC1: a signalling integration node involved in cell growth -- The regulation of the IGF-1/mTOR pathway by the p53 tumor suppressor gene functions -- mTOR signaling in angiogenesis -- mTORC1 signaling and hypoxia -- mTOR signaling in glioblastoma: lessions learned from bench to bedside -- mTOR and cancer therapy: general principles -- mTOR and cancer therapy: clinical development and novel prospects -- Drug combinations as a therapeutic approach for mTORC1 inhibitors in human cancer -- Downstream targets of mTORC1 -- Downstream of mTOR: translational and control of cancer -- Genome-wide analysis of translational control -- Translational control of cancer: implications for targeted therapy -- Downstream from mTOR: therapeutic approaches to targeting the eIF4F translation initiation complex.
  • Multiple myeloma 2005, Springer Protocols
    Identification of malignant plasma cells by mRNA in situ hybridization / Ross D. Brown and P. Joy Ho -- The SCID-hu myeloma model / Joshua Epstein and Shmuel Yaccoby -- The 5T2MM murine model of multiple myeloma: maintenance and analysis / Karin Vanderkerken ... [et al.] -- Determination of telomerase activity and telomere length / Kai-da Wu and Malcolm A.S. Moore -- Dendritic cell/myeloma hybrid vaccine / Dajing Xia, Tim Chan, and Jim Xiang -- Genetically engineered myeloma cell vaccine / Siguo Hao, Tim Chan, and Jim Xiang -- An in vitro osteoclast-forming assay to measure myeloma cell-derived osteoclast-activating factors / Andrew C.W. Zannettino ... [et al.] -- Clonality detection of the expanded T-cell populations in patients with multiple myeloma / Daniel M-Y. Sze -- Detecting mismatch repair defects in myeloma / Mark Velangi ... [et al.] -- Methylation-specific polymerase chain reaction / Oliver Galm and James G. Herman -- Making sense of DNA microarray data / Wei-min Liu, Sunhee K. Ro, and Walter H. Koch.Multiple myeloma: challenges and opportunities / Douglas Joshua, Ross D. Brown, and P. Joy Ho -- Immunophenotyping of plasma cells in multiple myeloma / Gema Mateo Manzanera, Jesús F. San Miguel Izquierdo, and Alberto Orfao de Matos -- Plasma cell labeling index / Philip R. Griepp and Shaji Kumar -- Conventional cytogenetics in myeloma / Lynda J. Campbell -- Multicolor spectral karyotyping in multiple myeloma / Jeffrey R. Sawyer -- Detection of chromosome 13 deletions by fluorescent in situ hybridization / Scott VanWier and Rafael Fonseca -- Comparative genomic hybridization for analysis of changes in DNA copy number in multiple myeloma / Pulivarthi H. Rao -- Southern blotting of IgH rearrangements in B-cell disorders / Edna Yuen and Ross D. Brown -- Identification and assembly of V genes as idiotype-specific DNA fusion vaccines in multiple myeloma / Surinder S. Sahota, Mark Townsend, and Freda K. Stevenson -- Identification of clonotypic IgH VDJ sequences in multiple myeloma / Brian J. Taylor ... [et al.] -- Real-time polymerase chain reaction of immunoglobulin rearrangements for quantitative evaluation of minimal residual disease in myeloma / Mara Compagno ... [et al.] -- Incomplete DJH rearrangements / David González and Ramón Garcia-Sanz ...
  • Multiple myeloma 2011, Springer
  • Part I. Epidemiology and clinical presentation -- Clinical presentation and differential diagnosis -- Epidemiology and etiology -- Part II. Pathology, pathophysiology and staging -- Cytogenetic diagnosis of myelodysplastic syndromes -- MDS stem cell biology -- The biology of myelodysplastic syndrome associated with Isolated del(5q) -- A personalized molecular pathogenesis of MDS -- Myelodysplastic/myeloproliferative neoplasms -- Classification and staging of myelodysplastic syndromes -- Immunophenotyping in myelodysplastic syndromes -- Prognostic models for patients with myelodysplastic syndromes -- Part III. Treatment -- Management of low-risk MIDS -- Management of high-risk myelodysplastic syndrome -- Hematopoietic cell transplantation (HCT) -- Part IV. MIDS in children -- Myelodysplastic syndrome in children.
  • Myeloid leukemia 2005, Springer Protocols
    Diagnosis and monitoring of AML1-MTG8 (ETO)-positive acute myeloid leukemia by qualitative and real-time quantitative RT-PCR / Khalid Tobal and John A. Liu Yin -- Diagnosis and monitoring of CBFB-MYH11-positive acute myeloid leukemia by qualitative and quantitative RT-PCR / Bert A. van der Reijden and Joop H. Jansen -- Detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia / Jan Cools, Elizabeth H. Stover, and D. Gary Gilliland -- FLT3 mutations in acute myeloid leukemia / Hitoshi Kiyoi and Tomoki Naoe -- WT1 overexpression in acute myeloid leukemia and myelodysplastic syndromes / Daniela Cilloni, Enrico Gottardi, and Giuseppe Saglio -- Classification of AML by DNA-oligonucleotide microarrays / Alexander Kohlmann ... [et al.] -- Classification of AML using a monoclonal antibody microarray / Richard I. Christopherson ... [et al.] --Isolation of RNA and DNA from leukocytes and cDNA synthesis / Joop H. Jansen and Bert A. van der Reijden -- Cytogenetics and FISH techniques in myeloid malignancies / Lynda J. Campbell -- Overview of real-time RT-PCR strategies for quantification of gene rearrangements in the myeloid malignancies / Christophe Picard, Monique Silvy, and Jean Gabert -- Diagnosis and monitoring of chronic myeloid leukemia by qualtitative and quantitative RT-PCR / Susan Branford and Timothy Hughes -- Detection of BCR-ABL mutations and resistance to imatinib mesylate / Susan Branford and Timothy Hughes -- Deletion of the derivative chromosome 9 in chronic myeloid leukemia / Lynda J. Campbell -- Diagnosis and monitoring of PML-RARA-positive acute promyelocytic leukemia by qualitative RT-PCR / Vincenzo Rossi, Laura Levati, and Andrea Biondi -- Diagnosis and monitoring of PML-RARA-positive acute promyelocytic leukemia by quantitative RT-PCR / Elisa Mokany ... [et al.] --Methods for the detection of the JAK2 V617F mutation in human myeloproliferative disorders / Peter J. Campbell ... [et al.] -- Overexpression of PRV-1 gene in polycythemia rubra vera and essential thrombocythemia / Maurizio Martini, Luciana Teofili, and Luigi M. Larocca -- Chimerism analysis following nonmyeloablative stem cell transplantation / Thomas Lion and Franz Watzinger.
  • Myeloma bone disease 2010, Springer
    Clinical Presentation of Myeloma Bone Disease / Rebecca Silbermann and G. David Roodman -- Imaging of Multiple Myeloma, Solitary Plasmacytoma, MGUS, and Other Plasma Cell Dyscrasias / Ronald C. Walker, Laurie Jones-Jackson, Twyla Bartel, Tracy Brown and Bart Barlogie -- Biochemical Markers of Bone Remodeling in Multiple Myeloma / Evangelos Terpos -- Radiation Therapy in Multiple Myeloma / Joel S. Greenberger -- Surgical Management of Bone Disease / Mohamad A. Hussein -- Bisphosphonates in the Treatment of Myeloma Bone Disease / James R. Berenson -- Osteonecrosis of the Jaw / Ashraf Badros -- Murine Models of Myeloma Bone Disease: The Importance of Choice / Peter I. Croucher, Karin Vanderkerken, Joshua Epstein and Babatunde Oyajobi -- RANK Ligand Is a Therapeutic Target in Multiple Myeloma / William C. Dougall, Michelle Chaisson-Blake, Howard Yeh and Susie Jun -- Osteoclast Activation in Multiple Myeloma / Sonia Vallet and Noopur Raje -- Potential Role of IMiDs and Other Agents as Therapy for Myeloma Bone Disease / Suzanne Lentzsch -- Proteasome Inhibitors and the Wnt Signaling Pathway in Myeloma Bone Disease / Claire M. Edwards and Gregory R. Mundy -- Mechanisms Involved in Osteoblast Suppression in Multiple Myeloma / Nicola Giuliani.
  • Diagnosis and classification of the BCR-ABL1-negative myeloproliferative neoplasms -- Genetics of the myeloproliferative neoplasms -- Cytogenetic findings in classical MPNs -- Prognostic factors in classic myeloproliferative neoplasms -- Therapy of polycythemia vera and essential thrombocythemia -- Conventional and investigational therapy for primary myelofibrosis -- Hematopoietic cell transplantation for myelofibrosis -- JAK2 inhibitors for therapy of myeloproliferative neoplasms -- Blastic transformation of classic myeloproliferative neoplasms -- Eosinophilic disorders: differential diagnosis and management -- Pathogenesis, diagnosis, classification, and management of systemic mastocytosis.
  • Nanomedicine and cancer 2012, CRCnetBASE
    Nanomedicine-based use of sirna in cancer / Guillermo N. Armaiz-Pena ... [et al.] -- Nanocarriers for gene delivery / Conchita Tros de Ilarduya and Gloria Gonzalez-Aseguinolaza -- Cancer cell photothermolysis and gold nanorod surface plasmons / Cheng-Lung Chen and Yang-Yuan Chen -- Tocotrienol loaded lipid nanoparticles in cancer / Sami Nazzal and Paul W. Sylvester -- Utilization of magnetic nanoparticles for cancer therapy / Deryl L. Troyer and Stefan H. Bossmann -- Nanoparticle probes and molecular imaging in cancer / Dongfang Liu and Ning Gu -- Iron and ethylcellulose nanoplatforms for cancer targeting / José L. Arias, Margarita López-Viota, and Ma Adolfina Ruiz -- Matrix scaffolds in cancer cell biology, physiological representation and nanoscale characterisation / Hsin-ya Chien ... [et al.] -- Fluorescence nanoprobe imaging tumor by sensing the acidic microenvironment / Lu Wang and Cong Li -- Magnetic nanorings and nanotubes for cancer detection and therapy / Hai Ming Fan and Malini Olivo -- Silicon nanowire arrays and other silicon nanostructures and their clinical applications to cancer / Murugan Veerapandian and Min-Ho Lee -- Silver nanomedicine and cancer / ... [et al.] -- Nanobubbles and their putative application to cancer medicine / Tianyi M. Krupka and Agata A. Exner -- Nano-strategies in the delivery of antitumor drugs to cancer / José L. Arias -- Gene silencing with sirna encapsulated nanoparticles to overcome tumor multidrug resistance / Mansoor M. Amiji, Francis Hornicek, and Zhenfeng Duan -- Nano-flow liquid chromatography mass spectrometric analysis of glycans in cancer / S. Hunter Walker and David C. Muddiman -- Composite nano-sensor arrays technology in lung cancer / Silvano Dragonieri, Giorgio Pennazza, and Marco Santonico -- Nano arsenic oxide (As2o3)/(Fe2o3) iron oxide complexes for liver cancer / Ziyu Wang and Dongsheng Zhang -- Hepatocellular carcinoma and midkine-antisense oligonucleotide-loaded nanoparticles / Licheng Dai, Yaoxing and Zhongjing -- Nanotechnology and nanostructures applied to head and neck cancer / Erik C. Dreaden, Mostafa A. El-Sayed, and Ivan H. El-Sayed.
  • Nasopharyngeal carcinoma 2013, Springer
    Diagnosis and clinical evaluation of nasopharyngeal carcinoma / Alan Soo-Beng Khoo and Kin-Choo Pua -- Histopathological diagnosis of nasopharyngeal carcinoma : looking beyond the blue book / John Nicholls and Gerald Niedobitek -- Descriptive, environmental and genetic epidemiology of nasopharyngeal carcinoma/ -- Bing-jian feng -- Epstein-Barr virus and the pathogenesis of nasopharyngeal carcinomas / Claire Gourzones, Pierre Busson and Nancy Raab-Traub -- Acquired genetic and epigenetic alterations in nasopharyngeal carcinoma / Kwok-Wai Lo, Grace Tin-Yun Chung and Ka-Fai To -- Cellular interactions in nasopharyngeal carcinomas / Claire Gourzones ... [et al.] -- Biological tools for NPC population screening and disease monitoring / Claire Gourzones ... [et al.] -- Medical imaging of nasopharyngeal carcinomas : current tools and applications / François Bidault -- Radiotherapy of NPC : current strategies and perspectives / John Kim -- The evolving role of systemic therapy in nasopharyngeal carcinoma : current strategies and perspectives / Edwin P. Hui and Anthony T.C. Chan -- Nasopharyngeal carcinoma immunotherapy current strategies and perspectives / Corey Smith and Rajiv Khanna -- Therapeutic induction of apoptosis in nasopharyngeal carcinoma / Carlo Bastianutto ... [et al.].
  • Introduction -- The science of developing cancer therapy -- Operations, oversight, and funding of cancer clinical trials -- Physician and patient participation in cancer clinical trials.
  • Natural killer T cells 2012, Springer
    Introduction : mechanisms of NKT-cell-mediated adjuvant activity and function of iPS-derived NKT cells / Masaru Taniguchi ... [et al.] -- Structure and recognition of antigens for invariant NKT cells / Bo Pei and Mitchell Kronenberg -- Invariant NKT cell-based vaccine strategies / John-Paul Jukes ... [et al.] -- Immune regulation of tumor immunity by NKT cells / Jessica J. O'Konek, Jay A. Berzofsky, and Masaki Terabe -- The regulation of CD1d+ and CD1d- tumors by NKT cells : the roles of NKT cells in regulating CD1d+ and CD1d- tumor immunity / Jianyun Liu, Gourapura J. Renukaradhya, and Randy R. Brutkiewicz -- DC-based immunotherapy targeting NKT cells / Shin-ichiro Fujii and Kanako Shimizu -- Therapeutic approaches utilising NKT cells / Stephen R. Mattarollo and Mark J. Smyth -- NKT cells or cancer patients and how models can inform therapeutic plans / Mark A. Exley, Lydia Lynch, and Michael Nowak -- Understanding the role of natural killer T cells in hematologic malignancies : progress and challenges / Natalia Neparidze and Madhav V. Dhodapkar -- Clinical trials with alpha-galactosylceramide (KRN7000) in advanced cancer / Famke L. Schneiders ... [et al.] -- Clinical trials of invariant natural killer T cell-based immunotherapy for cancer / Shinichiro Motohashi, Yoshitaka Okamoto, and Toshinori Nakayama.
  • Part 1.Natural Product Drugs and Cancer Therapeutics --The Impact of Natural Products Upon Cancer Chemotherapy /A. Ganesan --Identification and Development of Vascular Disrupting Agents: Natural Products That Interfere with Tumor Growth /Andrea T. Hooper, Frank Loganzo, Chad May and Hans-Peter Gerber --Discodermolide: Past, Present, and Future /Ross E. Longley --HDAC Inhibitors and Other Histone Modifying Natural Products as Emerging Anticancer Agents /Lilibeth A. Salvador and Hendrik Luesch --Natural Product Cytotoxins as Payloads for Antibody Drug Conjugates /Frank E. Koehn --Part 2.Advances in Natural Product Cancer Drug Discovery --Natural Product Scaffolds in Cancer Therapy /Christian P. Mang and Lars Ole Haustedt --The Role of Genetic Engineering in Natural Product-Based Anticancer Drug Discovery /Claudia Eva-Maria Unsin, Scott R. Rajski and Ben Shen --Accessing Anti-cancer Natural Products by Plant Cell Culture /Lisa M. Leone and Susan C. Roberts --Natural Products as Tools for Discovering New Cancer Targets /John A. Beutler.
  • Neuro-oncology Part I-II pt. I-II, 2012., ScienceDirect
    pt. II ScienceDirect
  • Neuroblastoma 2005, Springer
  • Neuroblastoma 2012, Springer
  • Neuroendocrine tumors 2011, Springer
    Global epidemiology of neuroendocrine tumors -- Pathology -- Multiple endocrine neoplasia -- Other genetic syndromes -- Imaging of neuroendocrine tumors -- Surgical management of sporadic gastrointestinal neuroendocrine tumors -- Management of neuroendocrine tumor hormonal syndromes -- Management of metastatic carcinoid tumors -- Medical management of islet cell carcinoma -- Poorly differentiated neuroendocrine tumors -- Hereditary and sporadic medullary thyroid carcinoma -- Adrenocortical carcinoma -- Pheochromocytoma -- Merkel cell carcinoma.
  • Neurofibromatoses 2008, Karger
    The neurofibromatoses: classification, clinical features, and genetic counselling / S.M. Huson -- Treatment and management of neurofibromatosis 1 / V.F. Mautner, E. Boltshauser -- Neurofibromatosis type 1 and other syndromes of the Ras pathway / D.A. Stevenson, J.J. Swensen, D.H. Viskochil -- NF1 gene structure and NF1 genotype/phenotype correlations / M. Upadhyaya -- NF1 mutational spectrum / L.M. Messiaen, K. Wimmer -- Clinical phenotypes in patients with NF1 microdeletions / S. Tinschert --Structure of the NF1 gene region and mechanisms underlying gross NF1 deletions / H. Kehrer-Sawatzki -- NF1 gene evolution in mammals / G. Assum, C. Schmegner -- Structure and function of neurofibromin / S. Welti, I. D'Angelo, K. Scheffzek -- Composition of neurofibromas, NF1 expression, and comparison of normal and NF1 haploinsufficient cells / J. Peltonen, S. Peltonen -- Somatic NF1 mutations in tumors and other tissues / T. De Raedt ... [et al.] -- NF2: mutations and management of disease / D.G.R. Evans, A. Wallace -- Function of merlin in genesis of tumours and other symptoms of NF2 / C.O. Hanemann -- Molecular studies on schwannomatosis / L. Kluwe.
  • Neurofibromatosis 1 -- Neurofibromatosis Type 2 (NF2) -- The Neurofibromatoses: Differential Diagnosis and Rare Subtypes -- Psychological Impact of the Neurofibromatoses -- Clinical Quiz: Diagnostic and Management Pitfalls of Neurocutaneous Disease.
  • Neuronal development / K.M. Giehl -- Organization of peripheral nerves in skin, musculoskeletal system, and viscera / M. von Düring, B. Fricke -- Neurotransmitter receptor-mediated signaling pathways as modulators of carcinogenesis / H.M. Schuller -- Neuronal markers in non-neuronal tissues / C. Hagel, D. Stavrou -- Chemotropic axon guidance molecules in tumorigenesis / A. Chédotal -- Neoneurogenesis and the neuro-neoplastic synapse / D. Palm, F. Entschladen -- Neurotransmitter effects on tumor cells and leukocytes / K. Lang, P. Bastian -- Stem cells and neurogenesis in tumors / J.A. Varner -- Potential inhibition of the neuro-neoplastic interactions: the clue of a GPCR-targeted therapy / J.-M. Muller -- The neuro-neoplastic synapse: does it exist? / K.S. Zänker.
  • Neutron capture therapy 2012, Springer
  • Nevogenesis 2012, Springer
  • Prognostic and therapeutic targets in the Ewing's family of tumors (PROTHETS) / P. Picci ... [et al.] -- Targeted therapies in Ewing's sarcoma / K. Scotlandi -- The CCN3 protein and cancer / B. Perbal -- EWS-FLI1 in Ewing's sarcoma: real targets and collateral damage / J. Ban ... [et al.] -- Molecular karyotyping in sarcoma diagnostics and research / H. Vauhkonen ... [et al] -- TuBaFrost: European virtual tumor tissue banking / P.H.J. Riegman ... [et al] -- Virtual microscopy in virtual tumor banking / M. Isabelle ... [et al] -- Harmonizing cancer control in Europe / U. Ringborg -- The diagnosis of cancer: from H&E to molecular diagnosis and back / J. Costa -- From morphological to molecular diagnosis of soft tissue tumors / M. Miettinen -- Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract / H. Höfler ... [et al] -- Integrating the diagnosis of childhood malignancies / D. López-Terrada -- Preclinical models for cell cycle-targeted therapies / M. Malumbres -- WWOX, a chromosomal fragile site gene and its role in cancer / D. Ramos and C.M. Aldaz -- From genome to proteome in tumor profiling: molecular events in colorectal cancer genesis / J.K. Habermann ... [et al] -- Effect of hypoxia on the tumor phenotype: the neuroblastoma and breast cancer models / L. Holmquist, T. Löfstedt, and S. Påhlman -- Methylation patterns and chemosensitivity in NSCLC / J.L. Ramírez ... [et al] -- Pharmacogenomics and colorectal cancer / H.J. Lenz -- Development of pharmacogenomic predictors for preoperative chemotherapy of breast cancer / L. Pusztai -- Vascular endothelial growth factor inhibitors in colon cancer / E. Díaz-Rubio -- Molecular imaging of cancer using PET and SPECT / A. Kjær -- MRS as endogenous molecular imaging for brain and prostate tumors: FP6 project "eTUMOR" / B. Celda ... [et al] -- From Linac to tomotherapy: new possibilities for cure? / G. Storme ... [et al] -- Targeting mTOR for cancer treatment / B. Rubio-Viqueira and M. Hidalgo -- Dual/pan-her tyrosine kinase inhibitors: focus in breast cancer / J. Albanell -- Antitumor-associated antigens IGGS: dual positive and negative potential effects for cancer therapy / E. Barberá Guillem and J.W. Sampsel -- Synergistic molecular mechanisms in hormone-sensitive breast cancer / A. Llombart Cussac.
  • History of the Mini Invasive Video Assisted Breast Surgery: From East to West -- Surgical Anatomy of the Breast: Key Points for Mini Invasive Video Assisted Approach -- Mini Invasive Video Assisted Breast Surgery: Feasibility and Safety -- Indication for Mini Invasive Video Assisted Mastectomy -- Diagnostic Work Out -- Operative Instruments -- Mini Invasive Video Assisted Mastectomy: Techniques -- Reconstructive Options -- Case Reports.
  • Nitric oxide and cancer: an overview -- A role for eNOS in oncogenic Ras-driven cancer -- Dual role of nitric oxide in cancer biology -- Nitric oxide expression in cancer -- S-nitrosylation: how cancer cells say NO to cell death -- Cytotoxic and protective activity of nitric oxide in cancers -- Cytotoxic/protective activity of nitric oxide in cancer -- Nitric oxide and life or death of human leukemia cells -- Inhibition of apoptosis by endogenous nitric oxide in chronic lymphocytic leukaemia -- Nitric oxide: a rate-limiting factor for metastases development -- Nitric oxide inhibits tumor cell metastasis via dysregulation of the NF-kB/Snail/RKIP loop -- Sensitizing effect of nitric oxide to cytotoxic stimuli -- Nitric oxide is a promising enhancer for cancer therapy -- Role of nitric oxide for modulation of cancer therapy resistance -- Breaking resistance: role of nitric oxide in the sensitization of cancer cells to chemo- and immunotherapy -- Prognostic significance of iNOS in human melanoma -- Prognostic significance of iNOS in hepatocellular carcinoma -- Prognostic significance of iNOS in esophageal cancer -- Prognostic significance of nitrative DNA damage in infection- and inflammation-related carcinogenesis -- Nitric oxide-releasing molecules for cancer therapy and chemoprevention -- Nitric oxide: monotherapy or sensitiser to conventional cancer treatments? -- Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies -- (S, R)-3-Pheynyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide (GIT-27NO): new dress for nitric oxide mission -- Nitric oxide donors are a new class of anti-cancer therapeutics for the reversal of resistance and inhibition of metastasis -- Role of inducible nitric oxide synthase (iNOS) in regulation of nitric oxide (NO) production and stabilization of nitric oxide of HIF-1a: potential role of Se-Methylselenocysteine(MSC), an antioxidant multi-targeted small molecule.
  • Non-Hodgkin lymphoma 2013, Springer
    Biology --Cancer Stem Cells: A Matter of Perspective /Peter J. Quesenberry, J. Reagan, B. Ramratnam, L. Goldberg --B and T Cell Development /Loren D. Fast --HIV Lymphomagenesis /Liron Pantanowitz, Antonino Carbone --Epstein-Barr Virus Lymphomagenesis and Therapeutic Targets /Huilan Rao, Roberto N. Miranda --Antigen-Driven Lymphomagenesis /Reve Shields, James N. Butera --Preclinical Modeling in Lymphoid Malignancies /Richa Dawar, Francisco J. Hernandez-Ilizaliturri --Prognostic Factors --Prognostic Factors in B-Cell Lymphomas /Diana O. Treaba, Diana O. Treaba --Prognostic Factors in Peripheral T-Cell Lymphomas /Brady E. Beltran, Jorge J. Castillo --Prognostic Factors in HIV-Associated Lymphoma /Jodi L. Layton, Jorge J. Castillo --Therapy --Future Directions in Aggressive Lymphomas /Guilherme F. Perini, Luis E. Fayad --New Monoclonal Antibodies for Indolent Non-Hodgkin Lymphoma /Tadeusz Robak --Current Therapies for T-cell Lymphomas /Francine M. Foss --Overview of Stem Cell Transplantation for Lymphoma /Karen Ballen --Autologous Hematopoietic Stem Cell Transplantation in Non-Hodgkin Lymphomas /Natthapol Songdej, Eric S. Winer --The Role of Hematopoietic Stem Cell Transplantation for HIV-Associated Lymphomas /Pascual Balsalobre, David Serrano, Jorge Gayoso, Juan Berenguer, José L. Díez-Martín --The Role of Hematopoietic Stem Cell Transplantation in Peripheral T-Cell Lymphomas /Jenna D. Goldberg, Carla Casulo, Steven M. Horwitz.
  • Apoptosis Inducer from Streblus asper Extracts for Cancer Chemoprevention /Azman Seeni, Nur Ayunie Zulkepli and Ridhwan Abdul Wahab --Apoptosis Induction by Nimbolide, a Limonoid from Azadirachta indica: Molecular Targets and Signaling Networks /Nagini Siddavaram and Vidya Priyadarsini Ramamurthi --Heterocyclics as Inducers of Apoptosis /Ahmed Kamal, Adla Mallareddy and Paidakula Suresh --Anthocyanins as Apoptotic Regulators /Jairam Vanamala, Sridhar Radhakrishnan, Lavanya Reddivari and Aaron Massey --Apoptosis as a Mechanism Involved in the Anticancer Effect of Dietary n-3 Polyunsaturated Fatty Acids /Simona Serini, Elena Fasano, Elisabetta Piccioni, Achille Renato Maria Cittadini and Gabriella Calviello --Apoptotic Pathways upon Arsenite Treatment /Dongyun Zhang and Chuanshu Huang --Flavokawains in Cancer Prevention and Treatment: Potentials and Challenges /Danielle D. Jandial, Anne R. Simoneau and Xiaolin Zi --Progesterone Receptor Modulators Induce Apoptosis in Mammary Tumors and Uterine Leiomyomas /Konstantin Christov and Ronald D. Wiehle --Apoptotic Regulators and Its Clinical Implications in Mammary Carcinoma /Subhadeep Das and Malay Chatterjee --Curcumin Analogs as Inhibitors of the Jak-STAT Signal Transduction Pathway /Jennifer Yang and Gregory B. Lesinski --Targeting Cancer by Betulin and Betulinic Acid /René Csuk.
  • Part 1.Basic Science and Experimental Studies on Stem Cell Mobilization --Preclinical Experience with AMD3100 for Mobilization of Hematopoietic Stem and Progenitor Cells --Molecular Pharmacology of CXCR4 Inhibition --Combination Strategies for Stem Cell Mobilization Targeting CXCR4 and S1P Receptors --Should We Stay or Should We Go Now? --Cell Adhesion and Mobilization Pathways of Hematopoietic Cells --Role of the CXCR4/CXCL12 Axis in Hematopoietic Stem Cell Trafficking --Part 2.Clinical Studies on Stem Cell Mobilization --Front matter --Early Studies of AMD3100/Plerixafor in Healthy Volunteers --The Current Role of Plerixafor in Stem Cell Mobilization for Hematopoietic Stem Cell Transplantation --Experience with Apheresis Procedures After Plerixafor Mobilisation --Influence of Different Stem Cell Mobilization Strategies on Graft Composition and Outcome of Autologous or Allogeneic Transplantation --Relevance and Clinical Implications of Tumor Cell Mobilization in Autologous Transplantation of Multiple Myeloma and Non-Hodgkin's Lymphoma --Plerixafor: Data from the Compassionate Use Program --Stem Cell Mobilization with Chemomobilization Plus Plerixafor in Hard-to-Mobilize Patients: The Experience at Kuopio University Hospital, Finland --Blood Stem Cell Mobilization in Solid Tumors: Experience with Plerixafor and Alternative Ways of Hematopoietic Stem Cell Mobilization --Mobilization with Chemotherapy + G-CSF + Plerixafor in Europe: The Italian Experience --Experience with Plerixafor in Poor Mobilizers --CXCR4 Antagonists --Part 3.CXCR4 Antagonists for Treatment of Leukemias and Solid Tumors --Front matter --Application of CXCR4 Inhibitors in Leukemia --CXCR4 Antagonists for the Treatment of CML --Targeting CXCR4 in Chronic Lymphocytic Leukemia: Preclinical Rationale and Early Clinical Experience --CXCR4-Blockade for Treatment of Breast Cancer --Molecular Imaging of CXCR4 Receptor Expression in Tumors --Part 4.Novel applications --Potential Use of CXCR4 Antagonists to Mobilize Endothelial and Mesenchymal Stem Cells --Strategies to Enhance Hematopoietic Stem Cell Engraftment Following Transplantation --Mobilization for Gene Therapy.
  • Nuclear oncology 2013, Springer
  • Criteria and classification of obesity in Japan and Asia-Oceania / M. Kanazaw ... [et al.] - Exercise and obesity in China / C. Chang -- Obesity in childhood: the Greek experience / A. Kafatos, C.A. Codrington, M. Linardakis -- Epidemiology of physical activity from adolescence to young adulthood / D.J. Aaron, Y.S. Jekal, R.E. Laporte -- Adolescent obesity and physical activity / N. Hwalla, A.M. Sibai, N. Adra -- Nutrition and physical activity of the population in Serbia / M. Pavlovic, V. Grujic, A. Oshaug -- Physical activity and body composition / D. Andreoli, A. De Lorenzo -- Syndrome X: clinical aspects / D. Labadarios -- Metabolic syndrome: is there a pathophysiological common denominator?: lessons learned from the Pima Indians / P.A. Tataranni -- Lifestyle-gene-drug interactions in relation to the Metabolic syndrome / L. Storlien ... [et al.] -- Coronary heart disease, genetics, nutrition and physical activity / M.B. Donati, I. Iacoviello -- Role of nutrients and physical activity in gene expression / R. De Caterina, R. Madonna -- Physical activity and hypertension: an overview / G.P. Rontoyannis --Omega-3 fatty acids and ventricular arrhythmias / A. Leaf, J.X. Kang, Y.-F. Xiao -- A method for the direct evaluation of the fatty acid status in a drop of blood from a fingertip in humans: application to population studies and correlations with biological parameters / F. Marangoni, C. Colombo, C. Galli -- Measurement error in the assessment of interaction between dietary and genetic factors in cohort studies of cancer / S.A. Bingham -- Cancer frequency in poor rural communities consuming a very limited diet / M. Muñoz Rivera ... [et al.] -- Omega-6/omega-3 polyunsaturated fatty acids ratio and breast cancer / P. Bougnoux, V. Maillard, V. Chajés -- Fish, [omega]-3 polyunsaturated fat intake and cancer at selected sites / A. Tavani ... [et al.] -- Cancer risk reduction by physical exercise / A. Willer.
  • Aberrant Signaling Pathways in Cancer: Modulation by the Dietary Flavonoid, Quercetin /Ramamurthi Vidya Priyadarsini and Siddavaram Nagini --Micronutrients and Cancer: Add Spice to Your Life /Sahdeo Prasad, Subash C. Gupta and Bharat B. Aggarwal --Chemoprevention of Prostate Cancer with Cruciferous Vegetables: Role of Epigenetics /Laura M. Beaver, David E. Williams, Roderick H. Dashwood and Emily Ho --Molecular Insight and Preclinical Perspective of Thymoquinone as Chemopreventive Agent and Therapeutic Adjunct in Cancer /Sanjeev Banerjee, Mansi Parasramka, Fazlul H. Sarkar and Ramzi M. Mohammad --Dietary Biofactors in the Management of Cancer: Myth or Reality? /Vidushi S. Neergheen-Bhujun, K. S. Kang, O. I. Aruoma and T. Bahorun --Nutritional Compounds as Chemopreventive Agents by Proteasome Inhibition /Kristin Landis-Piwowar, Elizabeth Smerczak, Jian Zuo and Q. Ping Dou --STAT Signaling in Cancer Prevention /Su-Ni Tang, Sharmila Shankar and Rakesh K. Srivastava --[gamma][delta] T Cells, Tea and Cancer /Jingwei Lu, Vincent J. Pompili and Hiranmoy Das --Phytochemical Intakes with a Mediterranean Diet: Levels Achievable with an Exchange List Diet and Potential Biomarkers in Blood /Zora Djuric --Plant Polyphenols and Their Role in Cancer Prevention and Chemotherapy /Sharmila Shankar, Brahma N. Singh and Rakesh K. Srivastava --Role of Food Micro-molecules in the Prevention of Cancer /Latha Sabikhi, Alok Jha, Sudhir Kumar Tomer and Ashish Kumar Singh.The Protective Role of Zinc in Cancer: A Potential Chemopreventive Agent /Bin Bao, Amir Ahmad, Azfar S Azmi, Zhiwei Wang and Sanjeev Banerjee, et al. --Diet-Induced Epigenetic Changes and Cancer Prevention: A Mantra for Healthy Living /Ajay Goel and Gaurav Chaturvedi --Western Diet-Induced Pancreatic Cancer /M. Mura Assifi and Guido Eibl --Intracellular Signaling Network as a Prime Chemotherapy Target of Green Tea Catechin, (-)-Epigallocatechin-3-gallate /Brahma N. Singh, Sharmila Shankar and Rakesh K. Srivastava --Role of Dietary Antioxidants in Cancer /C. M. Ajila and S. K. Brar --Curcumin: Structure, Biology and Clinical Applications /Sharmila Shankar and Rakesh K. Srivastava --Obesity, Cancer and Psychopathology: Can Vegetarian Diet Be of Help? /Vikas Kumar, Ajit Kumar Thakur and Shyam Sunder Chatterjee --Dietary Phytochemicals as Epigenetic Modulators in Cancer /Vijay S. Thakur and Sanjay Gupta --Modulation of the Nrf2 Signaling Pathway by Chemopreventive Dietary Phytoconstituents /Altaf S. Darvesh and Anupam Bishayee --Role of Fish Oil from Gene Expression to Pharmacological Effect in Cancer Prevention /Malay Chatterjee, Subhadeep Das, Mary Chatterjee and Kaushik Roy --Antioxidant Supplements: An Evidence-Based Approach to Health Benefits and Risks /Goran Bjelakovic, Dimitrinka Nikolova and Christian Gluud --Natural Antioxidants and Their Role in Cancer Prevention /Akanksha Singh, Akansha Jain, Birinchi Kumar Sarma, Alok Jha and H. B. Singh --Dietary and Non-dietary Phytochemicals in Cancer Control /Dhanir Tailor and Rana P. Singh.
  • Assessment of Malnutrition and Nutritional Therapy Approaches in Cancer Patients --Cancer Anorexia (CA) --Cancer Cachexia (CC) --Oral Mucositis --Nausea and Vomiting in Cancer --Cancer-Related Fatigue (CRF) --Treatment-Induced Enteritis (Radiation- or Combination Therapy-Induced Enteropathies) --Neurocognitive Impairment (NI) --Dysfunction of the Bowel/Constipation --Dysphagia.
  • Nutritional oncology. 2nd ed. 2006, ScienceDirect
  • Part I. The Science and Technology of Oncofertility -- Reproductive health after cancer -- Designing follicle-environment interactions with biomaterials -- Gamete preservation -- To transplant or not to transplant: that is the question -- Clinical cases in oncofertility -- Cancer genetics: risks and mechanisms of cancer in women with inherited susceptibility to epithelial ovarian cancer -- Protecting and extending fertility for females of wild and endangered mammals -- -- Part II. Historical and Legal Perspectives -- Placing the history of oncofertility -- Medical hope, legal pitfalls: potential legal issues in the emerging field of oncofertility -- Domestic and international surrogacy laws: implications for cancer survivors -- -- Part III. Clinical and Theoretical Ethics -- Adoption after cancer: adoption agency attitudes and perspectives on the potential to parent post-cancer -- Ovarian tissue cryopreservation and bioethical discourse -- Lessons of oncofertility for assisted reproduction -- Morally justifying oncofertility research -- Ethical dilemmas in oncofertility: an exploration of three clinical scenarios -- Participation in investigational fertility preservation research: a feminist research ethics approach -- Reproductive "choice" and egg freezing -- Impact of infertility: why ART should be a higher priority for women in the global south -- Oncofertility and informed consent: addressing beliefs, values, and future decision making -- -- Part IV. Religious Perspectives -- Bioethics and oncofertility: arguments and insights from religious traditions -- Sacred bodies: considering resistance to oncofertility in Muslim communities -- Unlikely motherhood in the Qur'an: oncofertility as devotion -- Technology and wholeness: oncofertility and Catholic tradition -- Jewish perspectives on oncofertility: the complexities of tradition -- --Part V. Ramifications for Education and Economics -- Oncofertility Saturday academy: a paradigm to expand the educational opportunities and ambitions of high school girls -- Myoncofertility.org: a web-based patient education resource supporting decision making under severe emotional and cognitive overload -- Anticipating ovarian tissue cryopreservation in the health-care marketplace: a willingness to pay assessment -- Perspectives on oncofertility from demography and economics -- For the sake of consistency and fairness: why insurance companies should cover fertility preservation treatment for iatrogenic infertility -- -- Part VI. Repercussions of Oncofertility for Patients and Their Families -- Health provider perspectives on fertility preservation for cancer patients -- Counseling and consenting women with cancer on their oncofertility options: a clinical perspective -- Fertility-related treatment choices of cancer patients: cancer-related infertility and family dynamics -- Whose future is it?: ethical family decision making about daughters' treatment in the oncofertility context -- -- Part VII. Healthcare Provider Stories and Final Thoughts -- Choosing life when facing death: understanding fertility preservation decision-making for cancer patients -- Discussing fertility preservation with breast cancer patients -- Warning: Google can be hazardous to your health: fertility preservation is an important part of cancer care -- Role of a patient navigator in fertility preservation -- Judaism and reproductive technology -- Reading between the lines of cancer and fertility: a provider's story -- Rewarding experience for a pediatric urologist -- Final thoughts.
  • Part I. Introduction --The emergence of a new discipline: oncofertility /Teresa K. Woodruff --Part II. Fertility risk and treatment options --Fertility management for women with cancer /Sanjay K. Agarwal and R. Jeffrey Chang --Fertility preservation in adult male cancer patients /Robert E. Brannigan --Managing fertility in childhood cancer patients /Kimberley J. Dilley --Fertility risk in pediatric and adolescent cancers /Clarisa R. Gracia and Jill P. Ginsberg --Part III. Oncofertility techniques and research --Bioengieneering and the ovarian follicle /Min Xu, Teresa K. Woodruff, and Lonnie D. Shea --The science of cryobiology /Steven F. Muller and John K. Critser --Ovarian tissue cryopreservation and transplantation: banking reproductive potential for the future /David Lee --Progress, history and promise of ovarian cryopreservation and transplantation for pediatric cancer patients /Yasmin Gosiengfiao --Part IV. Health care decision-making --Oncofertility and the social sciences /Karrie Ann Snyder --Shared decision making: fertility and pediatric cancers /Marla L. Clayman, Kathleen M. Galvin, and Paul Arnston --Part V. Ethical and psychosocial impact of cancer-related infertility --Today's research, tomorrows cures: the ethical implications of oncofertility /Leilah E. Backhus and Laurie Zoloth --The psychosocial context of cancer-related infertility /Matthew J. Loscalzo and Karen L. Clark --Childhood cancer: fertility and psychosocial implications /Karen E. Kinahan, Aarati Didwania, and Carrie L. Nieman --Fertility preservation and adolescent cancer patients: lessons from adult survivors of childhood cancer and their parents /Carrie L. Nieman ... [et al.] --Part VI. Training in a new medical discipline and medical guidelines --Oncofertility: a new medical discipline and the emerging scholar /Laxmi A. Kondapalli --Oncofertility Consortium consensus statement: guidelines for ovarian tissue cryopreservation /Leilah E. Backhus ... [et al.] --Part VII. Patient stories and oncofertility --Personal accounts of cancer and infertility /provided by Fertile Hope.
  • Oncogenomics handbook 2005, Springer
  • Oncologic imaging 2012, ScienceDirect
  • Oncology 2006, Springer
    Sect. 1. Principles of oncology. Evidence-based approach to oncology -- Principles of chemotherapy -- Principles of radiation oncology -- Principles of surgical therapy in oncology -- Principles of targeted and biological therapies -- Biologic principles of hematopoietic stem cell transplantation -- Evaluation of tumor markers: an evidence-based guide for determination of clinical utility -- Design and analysis of oncology clinical trials -- Ethics of clinical oncology research -- Informatics infrastructure for evidence-based cancer medicine -- Economics of cancer care -- Principles of screening for cancer -- Patient decision making -- Establishing an interdisciplinary oncology team -- Principles of complementary and alternative medicine for cancer -- Sect. 2. Translational basic science. Fundamental aspects of the cell cycle and signal transduction -- Viral carcinogenesis -- Environmental carcinogenesis -- Cancer metastasis -- Tumor immunology and immunotherapy -- Technologies in molecular biology: diagnostic applications -- Sect. 3. Cancer prevention and control. Cancer epidemiology -- Evidence-based cancer prevention research: a multidisciplinary perspective on cancer prevention trials -- Screening --Genetic screening and counseling for high-risk populations -- Behavior modification -- Sect. 4. Cancer imaging. Central nervous system imaging -- Breast imaging -- Imaging of throacic malignancies -- Imaging of gastrointestinal stromal tumor -- Genitourinary imaging -- Musculoskeletal imaging -- Positron emission tomography and cancer -- Sect. 5. Solid tumors. Central nervous system tumors -- Eye, orbit, and adnexal structures -- Head and neck cancer -- Lung cancer -- Therapy for malignant pleural mesothelioma -- Mediastinum -- Esophageal cancer -- Stomach -- Colon, rectal, and anal cancer management -- Adenocarcinoma and other small intestinal malignancies -- Cancer of the lung and bile ducts -- An evidence-based approach to the management of pancreatic cancer -- Renal cell cancer -- Ureter, bladder, penis, and urethra -- Prostate cancer -- Testis cancer -- Cervix, vulva, and vagina -- Gastational trophoblastic neoplasms -- Ovarian cancer -- Uterine malignancies -- Evidence-based management of breast cancer -- Thyroid and Parathyroid -- Tumors of the endocrine system -- Sarcomas of bone -- Soft tissue sarcoma --Cutaneous melanoma -- Nonmelanoma cutaneous malignancies -- Cancer of unknown primary site -- Solid tumors of childhood -- Sect. 6. Hematologic malignancies. Acute myeloid leukemia and the myelodysplastic syndromes -- Acute lymphoblastic leukemia -- Chronic lymphocytic leukemia and related chronic leukemias -- Chronic myeloid leukemia -- An evidence-based approach to the management of Hodgkin's lymphoma -- The non-Hodgkin's lymphomas -- Multiple myeloma -- Sect. 7. Practice of oncology. Superior vena cava syndrome -- Central nervous system emergencies -- Metabolic emergencies in oncology -- Surgical emergencies -- Oral complications of cancer therapy -- Alopecia and cutaneous complications of chemotherapy -- Infectious complications of cancer therapy -- Acute toxicities of therapy: pulmonary complications -- Cardiac complications -- Neurologic complications of therapy -- Acute toxicities of therapy: urologic complications -- Issues in vascular access with special emphasis on the cancer patient -- Management of cancer pain -- Nausea and vomiting in the cancer patient -- Nutritional support for the cancer patient --Paraneoplastic syndromes -- Malignant effusions -- Evidence-based use of hematopoietic growth factors for optimal supportive care of patients with cancer -- Management of the bone marrow transplant patient -- Management of anxiety and depression in adult cancer patients: toward an evidence-based approach -- Reproductive complications and sexual dysfunction in the cancer patient -- Metastatic cancer to the central nervous system -- Metastatic cancer in lung -- Surgical and regional therapy for liver metastases -- Metastatic cancer to bone -- Cancer in the immunosuppressed patient -- Cancer in the older population -- Chemotherapy in patients with organ dysfunction -- Management of the pregnant cancer patient -- Sect. 8. Cancer survivorship. Survivorship research: past, present, and future -- Late effects of cancer treatments -- Medical and psychosocial issues in childhood cancer survivors -- Medical and psychosocial issues in Hodgkin's disease survivors --Medical and psychosocial issues in testicular cancer survivors -- Medical and psychosocial issues in testicular cancer survivors -- Medical and psychosocial issues in gynecologic cancer survivors -- Medical, psychosocial, and health-related quality of life issues in breast cancer survivors -- Medical and psychosocial issues in prostate cancer survivors -- Physical and psychosocial issues in lung cancer survivors -- Cancer survivorship issues in colorectal cancer -- Medical and psychosocial issues in transplant survivors -- Second malignancies after radiation treatment and chemotherapy for primary cancers -- Psychosocial rehabilitation in cancer care -- Cancer advocacy.
  • Section I: Evaluation and management of musculoskeletal oncology problems -- Evaluation of bone tumors / Timothy A. Damron -- Evaluation of soft tissue tumors / Carol D. Morris -- Biopsy of musculoskeletal tumors / Edward A. Athanasian -- Treatment principles -- Surgical margins / Robert Quinn -- Benign tumors of bone / Cynthia M. Kelly -- Malignant bone lesions / Francis R. Patterson, Timoth A. Damron, and Carol D. Morris -- Soft tissue tumors / John Heiner and Jeremy White -- Pathologic fractures / Timothy A. Damron --Section II: Specific bone neoplasms and simulators -- Benign bone tumors -- Bone lesions / Felasfa M. Wodajo -- Cartilage lesions / Felasfa M. Wodajo -- Cystic lesions / Sung Wook Seo, Young Lae Moon, and Francis Young-In Lee -- Myogenic, lipogenic, and neural tumors / Sean V. McGarry and C. Parker Gibbs -- Fibrous lesions of bone / Sung Wook Seo, Young Lae Moon, and Francis Young-In Lee -- Giant cell tumor of bone / Sean V. McGarry and C. Parker Gibbs -- Vascular lesions / Sean V. McGarry and C. Parker Gibbs -- Other tumors of undefined neoplastic nature / Sean V. McGarry and C. Parker Gibbs -- Bone sarcomas -- Osteosarcoma / Francis R. Patterson -- Ewing sarcoma and primitive neuroectodermal tumor of bone / Bruce Rougraff -- Chondrosarcoma / R. Lor Randall and Kenneth J. Hunt -- Fibrous, fibrohistiocytic, and giant cell tumor malignancies / Hannah D. Morgan -- Notochordal tumors / Hannah D. Morgan -- Vascular sarcomas of bone / Hannah D. Morgan -- Myogenic, lipogenic, and epithelial bone sarcomas / Hannah D. Morgan -- Congenital and inherited bone conditions -- Familial adenomatous polyposis / Kathryn Palomino -- Beckwith-Wiedemann syndrome / Danielle A. Katz -- Skeletal dysplasias / Danielle A. Katz -- Retinoblastoma syndrome / Timothy A. Damron -- Rothmund-Thomson syndrome / Kathryn Palomino -- Werner syndrome / Kathryn Palomino -- Metastatic disease / Timothy A. Damron -- Hematologic malignancies / Valerae O. Lewis -- Metabolic bone diseases / Susan V. Bukata --Section III: Specific soft tissue neoplasms and simulators -- Benign soft tissue tumors / Timothy A. Damron and Gustavo de la Roza -- Soft tissue sarcomas / Carol D. Morris --Section IV: Basic science -- Cellular and molecular biology / Matthew J. Allen -- Growth and development of the musculoskeletal system / Donald E. Sweet and Thomas V. Smallman -- Genetic basis of musculoskeletal disorders / Sathappan S. Sathappan, Kirill Ilalov, and Paul E. Di Cesare -- Biomechanics / Frederick W. Werner and Joseph A. Spadaro -- Biomaterials / Joseph A. Spadaro, Michael T. Clarke, and Julie M. Hasenwinkel -- Principles of orthopaedic pharmacology / Carol D. Morris -- Bone form, function, injury, regeneration, and repair / Alexia Hernandez-Soria and Mathias Bostrom -- Articular cartilage structure, composition, and repair / Peter J. Roughley and Thomas V. Smallman -- Diarthrodial joints / Thomas V. Smallman, Kris Shekitka, and Donald Flemming -- Meniscal structure, function, repair, and replacement / Mark C. Drakos and Answorth A. Allen -- Intervertebral disk structure, composition, and mechanical function / Samuel A. Joseph, Jr., and Patrick Boland -- Tendon and ligament anatomy, biology, and biomechanics / Brian J. Harley and Joseph W. Bergman -- Peripheral nerve physiology, anatomy, and pathology / Shikha Sethi ... [et al.] -- Skeletal muscle anatomy, physiology, and mechanics / Bryan T. Kelly and William J. Robertson -- Infectious disorders of bone and joint / Thomas V. Smallman ... [et al.] -- Bacterial infection -- Granulomatous infection -- Infection associated with neuropathy -- Viral disorders -- Neoplasia / Matthew J. Allen.
  • 1. General Surgery -- Surgical Anatomy / Elisabeth Würinger -- Breast Cancer Surgery: Standard Principles / Florian Fitzal -- Oncoplastic Breast Surgery / Peter Schrenk -- 2. Oncoplastic Surgery (OPS) -- OPS and Breast Conserving Surgery (BSC) / Peter Schrenk, Elizabeth J. Hall-Findlay, Florian Fitzal, Andrea Grisotti and Donato Casella, et al. -- OPS and Mastectomy / Grant W. Carlson, Francesca De Lorenzi, Mario Rietjens, Andrea Manconi and Daniela Hoch, et al. -- Special Considerations / Florian Fitzal, Rupert Koller, Stefan Gärner, Elisabeth Grafinger-Witt and Mario Rietjens, et al.
  • Oncothermia 2011, Springer
  • Oral cancer metastasis 2010, Springer
  • Orbital tumors 2005, Springer
  • Origin of cancers 2010, Springer
  • Ovarian cancer 2008, Springer
  • Ovarian cancer. 2nd ed. 2009, Springer
  • Oxidation 2008, Springer
  • P53 in the clinics 2013, Springer
  • Pancreatic cancer 2010, Springer
    v. 1. Chapters 1-25 -- v. 2. Chapters 26-54.
  • Pancreatic cancer 2008, Springer
  • Pancreatic cancer 2005, Springer Protocols
  • Epidemiology of Mesothelioma -- Molecular Biology -- Serosal Anatomy and Anatomic Distribution of Mesothelioma -- Clinical Aspects of Mesothelioma -- Management of Malignant Serosal Effusions -- Pathologic Diagnosis and Classification of Mesothelioma -- Macroscopic Features of Mesotheliomas -- Classification and Histologic Features of Mesotheliomas -- Differential Diagnosis: Mesothelial Proliferations -- Differential Diagnosis: Other Mesothelial Lesions -- Differential Diagnosis: Nonmesothelial Lesions -- Differential Diagnosis: Nonmesothelial Tumors of the Serosal Cavity: Sarcomas -- Differential Diagnosis: Other Nonmesothelial Tumors.
  • Patient Surveillance After Cancer Treatment covers the history of cancer patient surveillance after curative-intent treatment, the rationale, the methodologies used in the past and at present, the methodologies that will probably emerge in the future, the costs of surveillance, the definitions of various terms used in the field, and how those who are interested in the topic can get more information about it from the internet. The secondary focus of the book is to publicize the need for well-designed, adequately powered randomized clinical trials comparing two (or more) surveillance strategies for each type of cancer.The audience includes all oncologists, cancer researchers, medical economists and policy makers in government and insurance companies, and finally, interested patients.This book is part of the Current Clinical Oncology series, which provides cutting-edge knowledge of cancer diagnosis, management, and treatment. World renowned experts share their insights in all the major fields of clinical oncology. From the fundamentals of pathophysiology to the latest developments in experimental and novel therapies, Current Clinical Oncology is an indispensable resource for today's practicing oncologist.
  • Pediatric bone sarcomas 2009, Springer
  • Pediatric cancer 2012, Springer
  • Pediatric lymphomas 2007, Springer
    Introduction and historical background: pediatric Hodgkin lymphoma -- Biology and pathology of Hodgkin's disease -- Treatment of pediatric Hodgkin lymphoma -- Treatment of relapsed/refractory Hodgkin lymphoma -- Non-Hodgkin's lymphoma: introduction and historical background -- Biology and pathology of pediatric non-Hodgkin lymphoma -- B-cell lymphoma/ Burkitt lymphoma -- Anaplastic large-cell lymphoma -- Precursor B and precursor T-cell lymphoblastic lymphoma -- Cutaneous T-cell lymphomas and rare T-cell non-Hodgkin lymphomas -- Lymphoproliferative disorders related to immunodeficiencies -- Late effects following lymphoma treatment.
  • Pediatric neoplasia 2012, Springer
  • Pediatric oncology 2005, Springer
    Acute Leukemia / Michael E. Rytting, Mary S. Choroszy, Demetrios Petropoulos and Ka Wah Chan -- Hodgkin Lymphoma and Non-Hodgkin Lymphoma / Ka Wah Chan, Demetrios Petropoulos, Eric L. Chang and Michael E. Rytting -- Brain Tumors: Diagnosis, Surgery and Radiotherapy, and Supportive Care / Joann L. Ater, Jeffrey S. Weinberg, Moshe H. Maor, Bartlett D. Moore and Donna R. Copeland -- Brain Tumors: Chemotherapy and Investigational Therapy / Joann L. Ater, Jeffrey S. Weinberg, Moshe H. Maor and Demetrios Petropoulos -- Wilms' Tumor / Norman Jaffe and Margaret G. Pearson -- Neuroblastoma / Joann L. Ater and Laura L. Worth -- Soft-Tissue Tumors / R. Beverly Raney, Richard J. Andrassy, Martin Blakely, Tina V. Fanning and Moshe H. Maor, et al. -- Osteosarcoma / Norman Jaffe and Margaret G. Pearson -- Ewing's Sarcoma / Cynthia E. Herzog, Anita Mahajan and Valerae O. Lewis -- Retinoblastoma / Misha Faustina, Cynthia E. Herzog and Dan S. Gombos -- Differentiated Thyroid Cancer / Rena Vassilopoulou-Sellin -- Medullary Thyroid Carcinoma / Robert F. Gagel -- Melanoma / Cynthia E. Herzog, Hafeez Diwan, Merrick I. Ross and Victor G. Prieto -- Novel Therapeutic Approaches / Sima S. Jeha and Laura L. Worth -- Supportive Care: Myelosuppression / Nidra I. Rodriguez Cruz, Renee M. Madden and Craig A. Mullen -- Supportive Care: Symptom Control / Renee M. Madden, Susannah E. Koontz-Webb, Donna S. Zhukovsky and Craig A. Mullen -- Behavioral Medicine in Cancer Care / Donna R. Copeland and Martha A. Askins -- The Adolescent and Young Adult Program / Sima S. Jeha and Martha A. Askins.
  • Pediatric oncology 2006, Springer
    General aspects of childhood leukemia -- Acute lymphoblastic leukemia -- Acute myelogenous leukemia -- Myelodysplastic syndrome -- Myeloproliferative syndromes (chronic myeloproliferative disorders) -- Non-Hodgkin lymphoma -- Hodgkin disease -- Histiocytoses -- Brain tumors -- Neuroblastoma -- Nephroblastoma (Wilms tumor) -- Soft tissue sarcoma -- Osteosarcoma -- Ewing sarcoma family of tumors -- Retinoblastoma -- Germ cell tumors -- Hepatic tumors -- Emergencies in pediatric oncology -- Oncological nursing care -- Psychology and psychosocial issues in children with cancer.
  • "Pediatric Radiation Oncology is the definitive text and reference on use of radiation therapy for childhood cancer. The fifth edition reviews all significant recent clinical trials--including, for the first time, significant European clinical trials--and provides increased coverage of international and Third World issues. The latest cancer staging guidelines are included. New chapters cover psychosocial aspects of radiotherapy for the child and family and medical management of pain, nausea, nutritional problems, and blood count depression in the child with cancer"--Provided by publisher.
  • Overview of childhood cancer : incidence, survival, and late effects -- Challenges of treating children with radiation therapy -- Leukemia -- Tumors of the central nervous system -- Hodgkin lymphoma -- Neuroblastoma -- Wilms' tumor -- Soft-tissue tumors : (rhabdomyosarcoma and other soft-tissue sarcomas) -- Bone sarcomas (osteosarcoma and Ewing's sarcoma) -- Retinoblastoma.
  • Penile cancer 2013, Springer
    Penile Cancer: Diagnosis and Management provides a comprehensive overview of penile cancer for medical and surgical urologists oncologists, and other healthcare professionals. This book highlights many of the significant advances made in this field, which include a discussion of penile-sparing surgical and radiotherapeutic approaches to select primary penile tumors typically of lower stage and grade as well as advances in our understanding of the epidemiology, risk factors, and pathophysiology of penile cancer. The book also addresses many of the novel diagnostic and therapeutic surgical appro
  • "Inside the Sixth Edition of this now-classic reference, you will discover encyclopedic coverage of topics ranging from basic science to sophisticated computer-based radiation therapy treatment planning and supportive care. The book's comprehensive scope and abundantly illustrated format provide you with better understanding of the natural history of cancer, the physical methods of radiation application, the effects of radiation on normal tissues, and the most judicious ways in which you can employ radiation therapy in patient care. Traditionally available as a printed textbook, now it comes with acompletely revamped digital experience, powered by Inkling! NEW to the Sixth Edition ... site-specific chapters include relevant background information on each tumor including epidemiology, pathology, diagnostic work-up, prognostic factors, treatment techniques, applications of surgery and chemotherapy, end results, and more. Over 1,400 full-color illustrationshighlight key concepts in tumor pathogenesis, diagnosis, and targeted radiation therapy. Increased emphasis on new approaches and technologies improve your understanding of three-dimensional treatment planning, intensity-modulated radiotherapy, combined modality therapy, and particle therapy. Greater emphasis on palliative and supportive carereflects the role of radiation treatment in non-curative roles. New editors and contributors let you benefit from their decades of experience. Digital version includes the complete text, index-based search, note sharing, regular content updates integrated into the text, and much more."
  • Scientific basis of cancer chemotherapy -- Norton-Simon hypothesis -- Drug resistance -- Principles of chemotherapy -- Clinical trials -- Hematopoietic growth factors -- Biologic response modifiers: principles of biotherapy -- Intraventricular and intrathecal therapy -- Intraperitoneal chemotherapy -- Intraarterial chemotherapy -- Hematopoietic stem cell transplantation -- Oral toxicity -- Dermatologic toxicity -- Extravasation -- Hypersensitivity reactions -- Ocular side effects of cancer therapeutics -- Cardiotoxicity of cancer therapy -- Pulmonary toxicity of chemotherapeutic agents -- Gastrointestinal complications of chemotherapy -- Hepatotoxicity of chemotherapeutic agents -- Chemotherapy-induced renal and electrolyte dysfunction -- Chemotherapy-induced peripheral neuropathy -- Vascular toxicity of antineoplastic agents -- Second malignancies after chemotherapy -- Chemotherapy in pregnancy -- Gonadal complications and teratogenicity of cancer therapy -- Central venous access for chemotherapy -- Systemic therapy for advanced melanoma -- Chemotherapy of primary brain tumors -- Chemotherapy for head and neck cancer -- Chemotherapy of lung cancer -- Breast cancer -- Gastrointestional cancer -- Endocrine tumors -- Chemotherapy of genitourinary cancer -- Chemotherapy of gynecologic cancers -- Chemotherapy of carcinoma of unknown primary site -- Chemotherapy of bone and soft tissue sarcomas -- Chemotherapy for pediatric solid tumors -- Chemotherapy for childhood leukemia -- Chemotherapy of Hodgkin lymphoma -- Non-Hodgkin lymphoma -- Chronic lymphocytic leukemia -- Acute myeloid leukemia -- Myelodysplastic syndromes -- Management of myeloproliferative disorders and chronic myeloid leukemia -- Chemotherapy of multiple myeloma -- Appendics: I: Chemotherapeutic agents -- II: Chemotherapy programs -- III: Common terminology criteria for adverse events (CTCAE) version 4.0.
  • PET in oncology 2008, Springer
  • PET Physics and Instrumentation / Brad Kemp -- PET Radiochemistry and Radiopharmacy / Mark S. Jacobson, Raymond A. Steichen and Patrick J. Peller -- PET/CT Interpretation / Patrick J. Peller -- Central Nervous System / Jeffrey A. Miller and Terence Z. Wong -- Head and Neck / Rathan M. Subramaniam, J. M. Davison, Ujas Parikh and M. Abou-Zied -- Chest / Rathan M. Subramaniam, J. M. Davison, D. S. Surasi, Gregory Russo and P. J. Peller -- Breast Cancer / Gustavo A. Mercier, Felix-Nicolas Roy and François Ba\0302enard -- Gastrointestinal / Roland Hustinx -- Genitourinary / Jacqueline Brunetti and Patrick J. Peller -- Gynecologic / Patrick J. Peller -- Musculoskeletal / Jeffrey J. Peterson -- Hematology / Rathan M. Subramaniam, Leonne Prompers, A. Agarwal, Ali Guermazi and Felix M. Mottaghy -- Dermatological / David Brandon and Bruce Barron -- Pediatric / Hossein Jadvar, Frederic H. Fahey and Barry L. Shulkin -- Assessment of Response to Therapy / Ali Gholamrezanezhad, Alin Chirindel and Rathan Subramaniam -- Metastatic Disease / Patrick J. Peller -- Radiotherapy Planning / Minh Tam Truong and Rathan M. Subramaniam -- Patients with HIV / Rathan M. Subramaniam, J. M. Davison, Devaki S. Surasi, T. Jackson and T. Cooley -- Pitfalls and Artifacts / Geoffrey Bates Johnson and Christopher Harker Hunt.
  • Pharmacogenetics 2010, Springer
    Principles of Cancer Treatment / William G. Newman and Fiona H. Blackhall -- Clinical Pharmacology and Anticancer Drugs / Cristina Rodríguez-Antona and Julia Kirchheiner -- Principles of Genetics and Pharmacogenetics / William G. Newman -- Pharmacogenetics in the Management of Breast Cancer / Sacha J. Howell -- Pharmacogenetics in Colorectal Cancer / Roberta Ferraldeschi -- Pharmacogenetics in Lung Cancer / Fiona Blackhall -- Pharmacogenetics and Cancer Treatment in Children / P. Kellie Turner and Gareth J. Veal -- Pharmacogenetics in Palliative Care / Andrew A. Somogyi -- Genetic Predictors of Normal Tissue Response to Radiotherapy / Catharine M.L. West, Gillian C. Barnett, Alison M. Dunning, Rebecca M. Elliott and Neil G. Burnet -- Cancer Pharmacogenetics in Industry / Mireille Cantarini -- Ethical Issues in Pharmacogenetics / Tara Clancy -- Economics of Cancer Pharmacogenetics / Katherine Payne -- Future Advances in Cancer Pharmacogenomics / William G. Newman.
  • Epidemiology of overweight/obesity and cancer risk -- Epidemiology of physical activity and cancer risk -- Energetics and cancer: exploring a road less traveled -- Calorie restriction, exercise, and colon cancer prevention: a mechanistic perspective -- Mechanisms linking obesity to cancer risk -- Mechanisms underlying the effects of physical activity on cancer -- Physical activity, weight control, and cancer prognosis.
  • Measuring endogenous electric fields / Richard Nuccitelli -- Investigation systems to study the biological effects of weak physiological electric fields / Francis X. Hart -- Endogenous bioelectric signals as morphogenetic controls of development, regeneration, and neoplasm / Michael Levin -- Stem cell physiological responses to noninvasive electrical stimulation / Igor Titushkin ... [et al.] -- Electrical signals control corneal epithelial cell physiology and wound repair / Colin D. McCaig -- Physiological electric fields can direct keratinocyte migration and promote healing in chronic wounds / Christine E. Pullar -- Electrical control of angiogenesis / Entong Wang ... [et al.] -- Inflammatory cell electrotaxis / Francis Lin and Christine E. Pullar -- Effects of DC electric fields on migration of cells of the musculoskeletal system / Najmuddin J. Gunja, Clark T. Hung, and J. Chlöe Bulinski -- Neuronal growth cone guidance by physiological DC electric fields / Ann M. Rajnicek -- Can applied voltages be used to produce spinal cord regeneration and recovery in humans? / Richard Ben Borgens -- Bioelectricty of cancer : voltage-gated ion channels and direct-current electric fields / Mustafa B. A. Djamgoz.
  • Pineal region tumors 2009, Karger
    Statistical analysis of pineal tumors based on the data of brain tumor registry of Japan / Shibui, S., Nomura, K. -- Pathology of pineal parenchymal tumors / Sato, K., Kubota, T. -- Occipital transtentorial approach and combined treatments for pineal parenchymal tumors / Tsumanuma, I., Tanaka, R., Fujii, Y. -- Role of stereotactic radiosurgery in the management of pineal parenchymal tumors -- Kano, H. ... [et al.] -- Pathology of intracranial germ cell tumors / Sato, K., Takeuchi, H., Kubota, T. -- Pineal germ cell tumors / Matsutani, M. -- Strategy of combined treatment of germ cell tumors / Sawamura, Y. -- Radiation therapy for intracranial germ cell tumors / Aoyama, H. -- Stereotactic radiosurgery for pineal and related tumors / Mori, Y. ... [et al.] -- Management of central nervous system germinoma : proposal for a modern strategy / Shibamoto, Y. -- Quality of life of extremely long-time germinoma survivors mainly treated with radiotherapy / Sugiyama, K. ... [et al.].
  • Plants that fight cancer 2004, CRCnetBASE
  • Polyploidy, aneuploidy, and the evolution of cancer / Lauren M.F. Merlo ... [et al.] -- Molecular mechanisms and function of the spindle checkpoint : a guardian of the chromosome stability / Daisuke Ito and Tomohiro Matsumoto -- Understanding cytokinesis failure / Guillaume Normand and Randall W. King -- DNA damage and polyploidization / Jeremy P.H. Chow and Randy Y.C. Poon -- Role of the p53 family in stabilizing the genome and preventing polyploidization / Flaminia Talos and Ute M. Moll -- Centrosomes, polyploidy, and cancer / Anette Duensing and Stefan Duensing -- Polyploidy : mechanisms and cancer promotion in hematopoietic and other cells / Hao G. Nguyen and Katya Ravid -- Polyploidization of liver cells / Séverine Celton-Morizur and Chantal Desdouets -- Analysis of cellular DNA content by flow and laser scanning cytometry / Zbigniew Darzynkiewicz, H. Dorota Halicka, and Hong Zhao.
  • This handbook, written in a clear and precise style, describes the principles of positron emission tomography (PET) and provides detailed information on its application in clinical practice. The first part of the book explains the physical and biochemical basis for PET and covers such topics as instrumentation, image reconstruction, and the production and diagnostic properties of radiopharmaceuticals. The focus then turns to the use of PET in clinical practice, including its role in hybrid imaging (PET-CT). A wide range of oncological applications are discussed, including for cancers of the head and neck, breast, lung, digestive system, urinary tract, female reproductive system, and prostate, lymphoproliferative disorders, melanoma, and musculoskeletal tumors. Uses of PET in cardiology, neurology, and psychiatry are also addressed. Characteristic findings are described and illustrated by numerous images, many of them in color. This book will be of value not only for nuclear medicine physicians and radiologists but also for all oncologists, surgeons, cardiologists, neurologists, psychiatrists, and residents with an interest in molecular imaging.
  • An overview of the management of thyroid cancer -- The UK evidence-based guidelines for the management of thyroid cancer: key recommendations -- Thyroid cancer multidisciplinary team and the organisational paradigm -- Thyroid cancer form the perspective of a patient -- The role of the specialist nurse -- The role of the clinical psychologist -- Thyroid nodules -- Thyroid cancer and the general practitioner -- The role of pathologist -- Thyroid cancer and the endocrinologist -- The specialist endocrine surgeon -- Initial thyroid surery for patient with differentiated thyroid carcinoma -- Management of cervical lymph nodes in differentiated thyroid cancer -- Complications of thyroid surgery -- Non-surgical management of thyroid cancer -- Fertility following treatment with iodine-131 for thyroid cancer -- Recombinant human TSH (rhTSH): use in papillary and follicular thyroid cancer -- Thyroglobulin -- Follow-up of patients with differentiated thyroid carcinoma --- Management of differentiated thyroid carcinoma patients with negative whole-body radioiodine scans and elevated serum thyroglobulin levels -- Medullary thyroid cancer: diagnosis and management -- Nonmedullary thyroid cancer and the role of the geneticist -- Thyroid cancer in childhood -- Radiation-induced thyroid cancer: lessons from Chernobyl -- The use of stable potassium iodide (KI) in the event of a nuclear emergency -- Ultrasound of the thyroid -- Diagnostic nuclear medicine investigations in the management of thyroid cancer -- CT and MRI in thyroid cancer -- Papillary microcarcinoma of the thyroid -- Rare thyroid cancers -- Management of anaplastic thyroid cancer -- Specialist palliative care for anaplastic thyroid carcinoma -- Emerging therapies for thyroid cancer -- Clinical trials for thyroid carcinoma: past, present, and future.
  • Pre-invasive disease 2011, Springer
  • Overview of the topic -- Meaning of SPC -- Importance of SPC -- Framework and methodology -- Lymphomas -- Leukemias -- Breast cancer (female) -- Lung cancer -- Cancers of the head and neck -- Gastrointestinal cancers -- Genitourinary cancers -- Gynecologic cancers -- Skin cancers -- Pediatric cancers -- Summary of significant SPC associations -- Population health priorities.
  • Epidemiology and risk factors -- Molecular pathogenesis -- Cellular origins of malignant glioma: the cancer stem cell polemic -- Principles of supportive care -- Principles of clinical trial design and response assessment -- Complications of therapy -- Neuropsychological function and quality of life -- Low-grade gliomas -- High-grade astrocytomas -- Anaplastic oligodendrogliomas and mixed gliomas -- Ependymomas -- Uncommon gliomas in adults: brainstem gliomas, pilocytic astrocytomas, and pleomorphic xanthastrocytomas -- Pediatric tumors -- Primary central nervous system lymphoma -- Meningiomas -- Pituitary adenomas -- Vestibular schwannomas -- Medulloblastomas -- Pineal region tumors -- Genetic syndromes -- Rare tumors -- Spinal tumors.
  • Primary liver cancer 2012, Springer
  • Primary liver cancer 2012, Springer
  • Primo vascular system 2012, Springer
  • Infections in patients with cancer : overview / Amar Safdar, Gerald Bodey, and Donald Armstrong -- Infections in hematopoietic stem cell transplant recipients / Georg Maschmeyer and Per Ljungman -- Infections in patients with hematologic malignancies / Genovefa Papanicolaou and Jayesh Mehta -- Infections in solid tumor patients / Alison G. Freifeld -- Infections in patients with hematologic malignancies treated with monoclonal antineoplastic therapy / André Goy and Susan O'Brien -- Postsurgery infections in cancer patients / Emilio Bouza ... [et. al] -- Management of infections in critically ill cancer patients / Henry Masur -- Management of the neutropenic patient with fever / Kenneth V. I. Rolston and Gerald P. Bodey -- Controversies in empiric therapy of febrile neutropenia / John R. Wingard -- Catheter-related infections in cancer patients / Iba Al Wohoush, Anne-Marie Chaftari, and Issam Raad -- Intravascular device-related infections : catheter salvage strategies and prevention of device-related infection / Nasia Safdar and Dennis G. Maki -- Pneumonia in the cancer patient / Scott E. Evans and Amar Safdar -- Noninfectious lung infiltrates that may be confused with pneumonia in the cancer patient / Rana Kaplan ... [et. al] -- Mucosal barrier injury and infections / Nicole M. A. Blijlevens and J. Peter Donnelly -- Bacterial colonization and host immunity / Coralia N. Mihu, Karen J. Vigil, and Javier A. Adachi -- Neutropenic enterocolitis and clostridium difficile infections / Amar Safdar ... [et. al] -- Management of reactivation of hepatitis B and hepatitis C during antineoplastic therapy / Marta Davila and Harrys A. Torres -- Management of genitourinary tract infections / Amar Safdar and Maurie Markman -- Central nervous system infections in cancer patients / Victor Mulanovich and Amar Safdar -- Endocarditis in oncology patients / Sara E. Cosgrove and Aruna Subramanian -- Skin disorders difficult to distinguish from infections / Sharone Hymes, Susan Chon, and Ana Ciurea -- Overview of invasive fungal disease in oncology patients / Amar Safdar -- Diagnosis of invasive fungal disease / Dionissios Neofytos and Kieren Marr -- Invasive candidiasis in management of infections in cancer patients / Matteo Bassetti ... [et. al] -- Management of aspergillosis, zygomycosis, and other clinically relevant mold infections / Konstantinos Leventakos and Dimitrios P. Kontoyiannis -- Cryptococcal disease and endemic mycosis / Johan A. Maertens and Hélène Schoemans -- Current controversies in the treatment of fungal infections / Christopher D. Pfeiffer, John R. Perfect, and Barbra D. Alexander --Fungal drug resistance and pharmacologic considerations of dosing newer antifungal therapies / Russell E. Lewis and David S. Perlin -- Immunotherapy for difficult-to-treat invasive fungal diseases / Brahm H. Segal, Amar Safdar, and David A. Stevens -- Cytomegalovirus in patients with cancer / Morgan Hakki, Per Ljungman, and Michael Boeckh -- Epstein-Barr virus, varicella zoster virus, and human herpes viruses-6 and -8 / Mini Kamboj and David M. Weinstock -- Respiratory viruses / Roy F. Chemaly, Dhanesh B. Rathod, and Robert Couch -- BK, JC and parvovirus infections in patients with hematologic malignancies / Véronique Erard and Michael Boeckh -- Antiviral resistance and implications for prophylaxis / Robin K. Avery -- Management of gram-positive bacterial disease : staphylococcus aureus, streptococcal, pneumococcal, and enterococcal infections / Samuel Shelburne and Daniel M. Musher -- Infections caused by aerobic and anaerobic gram-negative bacilli / Kenneth V. I. Rolston, David E.Greenberg, and Amar Safdar -- Listeriosis and nocardiosis / Heather E. Clauss and Bennett Lorber -- Antibacterial distribution and drug-drug interactions in cancer patients / Ursula Theuretzbacher and Markus Zeitlinger -- Mycobacterium tuberculosis infection / Michael Glickman -- Nontuberculous mycobacterial infections / Amar Safdar -- Parasitic infections in cancer patients : toxoplasmosis, strongyloidiasis and other parasites / Brian G. Blackburn and José G. Montoya -- Zoonoses in cancer patients / Donald Armstrong -- Antibiotic stewardship : considerations for a cancer Center / Coralia N. Mihu, Alla Paskovaty, and Susan K. Seo -- Controversies in antimicrobial stewardship / Graeme N. Forrest -- Prevention of antimicrobial resistance : current and future strategies / Cesar A. Arias and Adolf W. Karchmer -- Antibacterial, antifungal, and antiviral prophylaxis / Marcio Nucci and John R. Wingard -- Controversies in antimicrobial prophylaxis / Ben de Pauw and Marta Stanzani -- Infection prevention : protected environment and infection control / J. Peter Donnelly -- Prevention of tropical and parasitic infections : the immunocompromised traveler / Francesca F. Norman and Rogelio López-Vélez -- Prophylactic vaccination of cancer patients and hematopoietic stem cell transplant recipients / William Decker and Amar Safdar.
  • Gastrointestinal cancer: epidemioloy -- Gastrointestinal cancer: pathology and molecular pathology -- Gastrointestinal cancer: cancer genetics -- Gastrointestinal cancer: screening and surveillance -- Gastrointestinal cancer: surgical oncology -- Gastrointestional cancer management: biological aspects of radiation therapy -- Gastrointestinal cancer: medical oncology -- Gastrointestinal cancer: nutritional support -- Imaging of gastrointestinal malignancies -- Endoscopic diagnosis, staging, and management of gastrointestinal cancers -- An overview of outcomes research in gastrointestinal cancer -- Integrative oncology: complementary therapies in gastrointestinal cancer care -- Pain and symptom control -- Esophageal cancer: epidemiology, screening, and prevention -- The molecular genetics of esophageal cancer -- Esophageal cancer: pathology -- Esophageal cancer: anatomy and staging -- Esophageal cancer: clinical management -- Gastric cancer: epidemiology, screening, surveillance, and prevention -- Gastric cancer: molecular biology and genetics -- Gastric cancer: pathology -- Gastric cancer: staging systems and techniques -- Gastric cancer: clinical management -- Pancreas cancer: epidemiology and risk factors -- Pancreatic cancer: molecular biology and genetics -- Pancreas cancer: anatomy, staging systems, and techniques -- Pathology of pancreatic cancer -- Pancreas cancer: clinical management -- Hepatocellular carcinoma: epidemiology, screening and prevention -- Hepatocellular carcinoma: molecular biology and genetics -- Hepatocellular cancer: pathology -- Hepatocellular cancer: anatomy and staging -- Hepatocellular cancer: clinical management -- Cancer of the gallbladder and biliary tree: epidemiology -- Pathology of biliary tract cancer -- Cancers of the biliary tree: anatomy and staging -- Cancers of the biliary tree: clinical management -- Environmental and lifestyle issues in colorectal cancer -- Colorectal cancer: screening and surveillance -- Colorectal cancer: molecular biology and genetics -- Colorectal cancer: pathology -- Colorectal cancer: anatomy and staging -- Colon cancer: management of locoregional disease -- Rectal cancer: management of locoreginal disease -- Systemic therapy for metastatic colorectal cancer -- Colorectal cancer: surgery and local ablation of liver metasteses -- Anal canal cancer -- Neuroendocrine tumors of the gastrointestinal tract -- Lymphomas of the gastrointestinal tract -- Gastrointestinal stromal tumors -- Small bowel cancers -- Cancer of unknown primary site -- Malignant peritoneal mesothelioma.
  • Pt. I. General information -- Epidemiology and etiology of breast cancer -- Staging of breast cancer -- Molecular classification -- Prognostic and predictive factors -- Mechanisms of resistance to radiation -- Interaction of chemotherapy, radiotherapy, and timing -- Interactions of radiotherapy with hormonotherapy -- pt. II. Therapeutic results of radiotherapy in breast cancer -- Ductal carcinoma in situ -- Early stage breast cancer -- Locally advanced breast cancer -- Metastatic breast cancer -- pt. III. Radiotherapy atlas in breast cancer -- The organs at risk and radiation tolerance doses -- Chest wall and regional lymphatics -- Breast and tumor bed -- pt. IV. Modern radiotherapy techniques in breast cancer -- Simulation and patient fixation methods -- Three-dimensional planning techniques -- Inverse planning, intensity modulated radiation therapy, and image-guided radiation therapy -- Forward planning intensity modulated radiation therapy techniques -- Boost techniques -- Quality assurance -- Partial breast irradiation -- Hypofractionation -- Application of tomotherapy in breast cancer patients -- pt. V. Radiotherapy complications in breast cancer -- Radiotherapy complications.
  • Difficult pain syndromes: neuropathic pain, bone pain, and visceral pain -- Opioid pharmacotherapy -- Nonpharmacologic management of pain -- Interventional approaches to pain -- Pathology of bone metastases-implications for treatment -- Pathophysiology of chemotherapy-induced peripheral neuropathy -- Cancer-related fatigue -- Fever and sweats -- Hot flashes -- Anorexia/weight loss -- Dysphagia/speech rehabilitation in palliative care -- Chemotherapy-related nausea and vomiting and treatment-related nausea and vomiting -- Assessment of management of chronic nausea and vomiting -- Diarrhea, malabsorption, and constipation -- Bowel obstruction -- Diagnosis and management of effusions -- Hiccups and other gastrointestinal symptoms -- Biology of treatment-induced mucositis -- Oral manifestations and complications of cancer therapy -- Approach to liver metastases in palliative oncology -- Palliative endoscope procedures -- Palliative interventional radiologic procedures -- Pruritus -- Treatment of tumor-related skin disorders -- Dermatologic adverse events during treatment -- Management of pressure ulcers and fungating wounds -- Lymphedema -- Principles of fistula and stoma management -- Dyspnea in the cancer patient -- Hemoptysis, airway obstruction, bronchospasm, cough, and pulmonary complications/symptoms of cancer and its treatment -- Prevention, assessment, and management of treatment-induced cardiac disease in cancer patients -- Management of hypercoagulable states and coagulopathy -- Urologic issues in palliative care -- Impact of hepatic and renal dysfunction on pharmacology of palliative care drugs -- Hypercalcemia -- Metabolic disorders in the cancer patient -- Infectious complications/management --Management of intracranial metastases -- Management of spinal cord and cauda equina compression -- Recognizing and managing delirium -- Treating depression at the end of life -- Anxiety -- Cognitive decline following cancer treatment -- Substance-abuse issues in palliative care -- Epidemiology and prognostication in advanced cancer -- Hospice -- Cultural issues -- Communication during transitions of care -- The family meetings -- Psychosocial consequences of advanced cancer -- Disorders of sexuality and reproduction -- Caregiving in the home -- Management of symptoms in the actively dying patient -- Spirituality -- Bereavement care -- Staff stress and burnout -- Advance directives, decision making, and withholding and withdrawing treatment -- Palliative care: ethics and the law -- Hematologic support of the cancer patient -- Issues in nutrition and hydration -- Complementary, alternative, and integrative therapies in oncology -- Geriatric palliative care -- Palliative care in pediatrics -- Hematopoietic stem cell transplantation and supportive care -- Long-term survivorship: late effects -- Survivorship issues in adults -- Outcomes assessment in palliative care -- Measurement of quality of life outcomes -- Research issues: ethics and study design.
  • Basic biostatistics for the clinical trialist / Elizabeth G. Hill and Elizabeth Garrett-Mayer -- Fundamental concepts in clinical pharmacology / Daniel L. Gustafson and Erica L. Bradshaw-Pierce -- Bioanalycial methods in clinical drug development / Walter J. Loos, Peter de Bruijn and Alex Sparreboom -- Preclinical models for anticancer drug development / Edward A. Sausville -- Phase I clinical trials with anticancer agents / Stephen Leong ... [et al.] -- Phase II trials with anticancer agents / Hui K. Gan, J. Jack Lee and Lillian L. Siu -- Phase III clinical trials with anticancer agents / Wendy R. Parulekar and Daniel J. Sargent -- Pharmacokinetic studies in early anticancer drug development / Alex Sparreboom and Sharyn D. Baker -- Pharmacodynamic studies in early phase drug development / D. Ross Camidge, Robert C. Doebele and Antonio Jimeno -- Prediction of antitumor response / Fred R. Hirsch and Yu Shyr -- Imaging studies in anticancer drug development / David A. Mankoff -- Role of the U.S. Food and drug administration in cancer drug development / Ann T. Farrell, Ramzi N. Dagher and Richard Pazdur -- Early clinical trials with cytotoxic agents / M.J.A. de Jonge and Jaap Verweij -- Challenges and successes in developing effective anti-angiogenic agents / Laura Q.M. Chow and S. Gail Eckhardt -- Targeted therapeutics in cancer treatment / Colin D. Weekes and Manuel Hidalgo -- Cancer chemoprevention / Christopher H. Lieu, William N. William Jr. and Scott Lippman -- Combined modality therapy in cancer management / David Raben and Kyle Rusthoven -- Cancer vaccines / Daniel Laheru -- Optimising the development of antibodies as treatment for cancer / Craig P. Carden, Hendrik-Tobias Arkenau and Johann S. de Bono -- Oligonucleotide therapeutics / Cy A. Stein, Britta Hoehn and John Rossi -- Anticancer drug development in pediatric patients / Lia Gore and Margaret Macy -- Clinical trials in special populations / S. Percy Ivy ... [et al.] -- NCI-sponsored clinical trials / Andriana Papaconstantinou and Janet E. Dancey.
  • Cancer biotherapy : general principles / Robert K. Oldham -- The pathogenesis of cancer metastasis : relevance to therapy / Sun-Jin Kim ... [et al.] -- Developmental therapeutics and the design of clinical trials / Robert K. Oldham -- Recombinant proteins and gnomics in cancer therapy / Kapil Mehta ... [et al.] -- Current concepts in immunology / Robert K. Oldham -- Therapeutic approaches to cancer-associated immune suppression / Robert K. Oldham -- Cancer vaccines / Kenneth A. Foon and Malek M. Safa -- Cytokines / Walter M. Lewko and Robert K. Oldham -- Interferons : therapy for cancer / David Goldstein ... [et al.] -- Monoclonal antibody therapy / Robert O. Dillman -- Immunotoxins / Arthur E. Frankel, Jung-Hee Woo, and David M. Neville -- Drug immunoconjugates / Malek Safa, Kenneth A. Foon, and Robert K. Oldham -- Targeted radionuclide therpy of cancer / John M. Pagel ... [et al.] -- Stem cell/bone marrow transplantation as biotherapy / Robert K. Oldham -- Cellular immunotherapy (CI), where have we been and where are we going? / John R.Yanelli -- Growth and differentiation factors as cancer therapeutics / Kapil Mehta, Robert K. Oldham, and Bulent Ozpolat -- Granulocyte colony-stimulating factor : biology and clinical potential / MaryAnn Foote and George Morstyn -- Granulocyte-macrophage colony-stimulating factor / MaryAnn Foote and George Morstyn -- Cancer gene therapy / Donald J. Buchsbaum ... [et al.] -- Regulatory process for approval of biologicals for cancer therapy / Antonio J. Grillo-López -- Cancer biotherapy : 2009 disease-related activity / Robert K. Oldham and Robert O. Dillman -- Biological therapy of melanoma / Robert K. Oldham -- Biological therapy of genitourinary cancer / Robert K. Oldham -- Biological therapy of colon cancer / Robert O. Dillman -- Biological therapy of breast cancer / Robert O. Dillman -- Biological therapy of lung cancer / Robert O. Dillman -- Biological therapy of B and T cell lymphoproliferative disorders / Robert O. Dillman -- Biological therapy of multiple myeloma / Robert K. Oldham -- Biological therapy of squamous cell cancers of the head and neck / Robert O. Dillman -- Biological therapy of glioblastoma / Robert O. Dillman -- Speculations for 2009 and beyond / Robert K. Oldham.
  • Plastic surgery: a component in the comprehensive care of cancer patients -- The principles of cancer reconstruction -- Breast reconstruction: timing and coordination with adjuvant therapy -- Breast reconstruction: autogenous tissue -- Breast reconstruction: implant and nipple reconstruction -- Skin cancer and reconstruction -- Lip, cheek, and scalp reconstruction -- Reconstruction of mandible, maxilla, and skull base -- Pharynx, cervical esophagus, and oral cavity reconstruction -- Concepts in nasal reconstruction -- Extremity reconstruction -- Abdominal wall tumors and their reconstruction -- Reconstruction of the intra-abdominal pelvis and the perineum -- Management of chemotherapeutic agent extravasation and radiation therapy adverse effects.
  • Basic Principles of Cancer Genetics / Leif W. Ellisen and Daniel A. Haber -- Principles of Cancer Genetic Counseling and Genetic Testing / Kristen M. Shannon and Devanshi Patel -- Genetics of Hereditary Breast Cancer / Paula D. Ryan -- Surgical Management of Hereditary Breast and Ovarian Cancer / Michelle C. Specht, Marcela G. del Carmen and Barbara L. Smith -- Hereditary Colon Cancer: Colonic Polyposis Syndromes / Andrew T. Chan and Daniel C. Chung -- Hereditary Colon Cancer: Lynch Syndrome / Eunice L. Kwak and Daniel C. Chung -- Hereditary Pancreatic Cancer / Janivette Alsina and Sarah P. Thayer -- Hereditary Diffuse Gastric Cancer / Prakash K. Pandalai and Sam S. Yoon -- Familial Renal Cell Cancers and Pheochromocytomas / Gayun Chan-Smutko and Othon Iliopoulos -- Familial Atypical Mole Melanoma (FAMM) Syndrome / Elizabeth D. Chao, Michele J. Gabree and Hensin Tsao -- Multiple Endocrine Neoplasia / Yariv J. Houvras and Gilbert H. Daniels -- Pediatric Malignancies: Retinoblastoma and Wilms' Tumor / David A. Sweetser and Eric F. Grabowski -- Neurofibromatosis and Schwannomatosis / Miriam J. Smith and Scott R. Plotkin -- The HapMap Project and Low-Penetrance Cancer Susceptibility Alleles / Edwin Choy and David Altshuler -- Somatic Genetic Alterations and Implications for Targeted Therapies in Cancer (GIST, CML, Lung Cancer) / Alice T. Shaw, Eyal C. Attar, Edwin Choy and Jeffrey Engelman.
  • Section I. Introduction of cancer biology and cancer genetics -- Section II. Molecular techniques -- Section III. Molecular tests and cancer management -- Section IV. Molecular diagnostics of common malignancies -- Section V. Molecular basis of cancer therapeutics -- Section VI. Personalized medicine and targeted therapy of cancer -- Section VII. Future of molecular diagnostics and personalized cancer medicine.
  • Selecting the right targets for cancer therapy / Miguel H. Bronchud -- Clinical importance of prognostic factors: moving from scientifically interesting to clinically useful / N. Lynn Henry and Daniel F. Hayes -- Genetic markers in sporadic tumors / Elena Tamborini ... [et al.] -- Genetic markers in breast tumors with hereditary predisposition / Tatyana A. Grushko and Olufunmilayo I. Olopade -- Circulating tumor markers / Alan Horwich and Gill Ross -- Antibody-based proteomics analysis of tumor cell signaling pathways / Steven Pelech and Hong Zhang -- Gene expression arrays for pathway analysis in cancer research / Xiang Sean Yu ... [et al.] -- Signaling pathways in cancer / Daniel Kalderon -- Estrogen receptor pathways and breast cancer / Jing Peng and V. Craig Jordan -- Cyclin-dependent kinases and their regulators as potential targets for anticancer therapeutics / Marcos Malumbres -- Angiogenesis switch pathways / Jaume Piulats and Francesc Mitjans -- Apoptosis pathways and new anticancer agents / Frank A.E. Kruyt, Jose A. Rodriguez, and Giuseppe Giaccone -- Genomic instability, DNA repair pathways and cancer / Gabriel Capellá, Josep Balart, and Miquel Angel Peinado -- Epigenomics and cancer / Isabel Lopéz de Silanes and Manel Esteller -- Harnessing the power of immunity to battle cancer: Much ado about nothing or All's well that ends well? / Angelo A. Cardoso -- Aurora Kinases: a new target for anticancer drug development / Teresa Macarulla, Francisco Javier Ramos, and Josep Tabernero -- Emerging molecular therapies: drugs interfering with signal transduction pathways / Alison H.M. Reid, Richard Baird, and Paul Workman -- Suicide gene therapy / Silke Schepelmann, Ion Niculescu-Duvaz, and Caroline J. Springer -- Genotypes that predict toxicity and genotypes that predict efficacy of anticancer drugs / Rosario García-Campelo ... [et al.] -- A personal account of the chemoprevention of breast cancer: possible or not possible? / V. Craig Jordan.
  • Cell death : history and future / Zahra Zakeri and Richard A. Lockshin -- Caspase mechanisms / Guy S. Salvesen and Stefan J. Riedl -- The mitochondrial death pathway / Anas Chalah and Roya Khosravi-Far -- Apoptotic pathways in tumor progression and therapy / Armelle Melet ... [et al.] -- Therapeutic targeting of death pathways in cancer : mechanisms for activating cell death in cancer cells / Ting-Ting Tan and Eileen White -- Overcoming resistance to apoptosis in cnacer therapy / Peter Hersey, Xu Dong Zhang, and Nizar Mhaidat -- Trail receptors : targets for cancer therapy / Robin C. Humphreys and Wendy Halpern -- Rational design of therapeutics targeting the BCL-2 family : are some cancer cells primed for death but waiting for a final push? / Victoria Del Gaizo Moore and Anthony Letai -- Autophagy and tumor suppression : recent advancesin understanding the link between autophagic cell death pathways and tumor development / Shani Bialik and Adi Kimchi -- Regulation of programmed cell death by the P53 pathway / Kageaki Kuribayashi and Wafik S. El-Deiry -- Regulation of programmed cell death by NF-[kappa]B and its role in tumorigenesis and therapy / Yongjun Fan ... [et al.] -- Targeting proteasomes as therapy in multiple myeloma / Dharminer Chauhan, Teru Hideshima, and Kenneth C. Anderson -- Histone deacetylase inhibitors : mechanisms and clinical significance in cancer : HDAC inhibitor-induced apoptosis / Sharmila Shankar and Rakesh K. Srivastava -- RNA interference and cancer : endogenous pathways and therapeutic approaches / Derek M. Dykxhoorn, Dipanjan Chowdhury, and Judy Lieberman -- Cancer stem cells and impaired apoptosis / Zainab Jagani and Roya Khosravi-Far.
  • Prominin-1 (CD133) 2013, Springer
  • Virology and pathogenesis / Pfister, H. -- Epidemiology of mucosotropic papillomaviruses / Gissmann, L. -- Condylomata acuminata / Gross, G. -- Recurrent respiratory papillomatosis / Wittekindt, C.; Wagner, S.; Klussmann, J.P. -- Cervical cancer and intraepithelial neoplasia / Schneider, A. ... [et al.] -- Cancer and intraepithelial neoplasia of the vulva and vagina / Petry, K.U. -- Penile cancer and penile intraepithelial neoplasia / Gross, G. -- Anal cancer and intraepithelial neoplasia / Wieland, U. ; Kreuter, A. -- Tonsillar cancer / Klussmann, J.P.; Wagner, S.; Wittekindt, C. -- Cytology / Ikenberg, H. -- Concepts of biomarker development / von Knebel Doeberitz, M.; Vinokurova, S.; Reuschenbach, M. -- Detection of human papillomavirus DNA and RNA / Ikenberg, H. -- Human papillomavirus testing in primary screening for cervical cancer / Petry, K.U. -- Primary prevention by vaccination / Kaufmann, A.M.; Gissmann, L.
  • Mechanistic aspects of COX-2 expression in colorectal neoplasia -- Mode of action of aspirin as a chemopreventive agent -- Coxibs: pharmacology, toxicity and efficacy in cancer clinical trials -- COX-2 active agents in the chemoprevention of colorectal cancer -- New NSAID targets and derivatives for colorectal cancer chemoprevention -- Aspirin in prevention of sporadic colorectal cancer: current clinical evidence and overall balance of risks and benefits -- Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal neoplasia -- Genetics, inheritance and strategies for prevention in populations at high risk of colorectal cancer (CRC).
  • Prostate biopsy 2008, Springer
    Defining the problem : from subclinical disease to clinically insignificant prostate cancer / Wael Sakr -- What every patient should know about prostate cancer before he submits to biopsy of his prostate / Thomas A. Stamey, Rosalie Nolley, and Dorothea Torti -- Prostate-specific antigen and prostate cancer screening / Stacy Loeb, Misop Han, and William J. Catalona -- The role of complexed prostate-specific antigen in prostate cancer screening / Matthew E. Nielsen and Alan W. Partin -- Newly recognized forms of prostate-specific antigen and emerging molecular markers / Eduardo I. Canto and Kevin M. Slawin -- The role of prostate-specific antigen velocity in the diagnosis and management of prostate cancer / H. Ballentine Carter -- Prostate cancer screening : navigating the controversy / Timothy C. Brand and Ian M. Thompson -- Prostate cancer nomograms and how they measure up to neural networks / Pierre I. Karakiewicz and Michael W. Kattan -- Preparation for prostate biopsy / Alan M. Nieder and Mark S. Soloway -- Principles of prostate ultrasound / Martha K. Terris -- Minimizing pain and optimizing patient experience during prostate biopsy / J. Stephen Jones -- Prostate biopsy techniques / Katsuto Shinohara -- Biopsy strategies-how many and where? / Joseph C. Presti, Jr. -- Transperineal prostate biopsy / Paolo Emiliozzi and Vito Pansadoro -- Repeat prostate biopsies and the Vienna nomograms / Bob Djavan and Sibylle Marihart -- Saturation biopsy for detection and characterization of prostate cancer / J. Stephen Jones -- Pathologic implications of prostate biopsy / Ming Zhou and Cristina Magi-Galluzzi -- Complications of transrectal ultrasound-guided prostate biopsy / Sam S. Chang and Michael S. Cookson -- Management and controversies of high-grade prostatic intraepithelial neoplasia and atypical small acinar proliferation on prostate biopsy / Alon Z. Weizer ... [et al.] -- Future directions in prostate cancer diagnosis / Nicholas J. Fitzsimons ... [et al.]
  • Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Practice -- Prostate Needle Biopsy Sampling Techniques: Impact on Pathological Diagnosis -- Diagnosis of Limited Cancer in Prostate Biopsy -- Immunohistochemistry in Prostate Biopsy Evaluation -- Contemporary Approach to Gleason Grading of Prostate Cancer -- Histologic Variants of Prostate Carcinoma -- Benign Mimics of Prostate Carcinoma -- Atypical Cribriform Lesions of the Prostate Gland: Emerging Concepts of Intraductal Carcinoma of the Prostate (IDC-P) -- High-Grade Prostatic Intraepithelial Neoplasia -- Atypical Glands Suspicious for Cancer -- Spindle Cell Lesions of the Prostate Gland -- Treatment Effect in Benign and Malignant Prostate Tissue -- Molecular Biology of Prostate Cancer and Emerging Diagnostic and Prognostic Biomarkers -- Biopsy Specimen Handling, Processing, Quality Assurance Program -- Reporting of Prostate Biopsy.
  • Prostate cancer 2013, Springer
  • Prostate cancer 2007, Springer
  • Prostate cancer 2013, Springer
  • Prostate cancer 2008, Springer
    Histopathology and molecular biology of prostate atrophy: a lesion associated with inflammation, prostate intraepithelial neoplasia, and prostate cancer -- Epigenetic gene silencing in prostate cancer -- Inherited genetic changes in prostate cancer -- Prostate molecular oncogenesis: gene deletions and somatic mutations -- Somatic genetic changes in prostate cancer: androgen receptor alterations -- Androgen receptor in prostate cancer progression -- Epigenetic modification and aceylation of androgen receptor regulate prostate cellular growth -- Estrogen receptor a [alpha] and b [beta] in the regulation of normal and malignant prostate epithelium -- Estrogen action in normal prostate epithelium and in prostate cancer -- Hypoxia-inducible factor 1 in the angiogenesis of prostate cancer -- Signal transduction by the Ras-MAP kinase pathway in prostate cancer progression -- Transcription factors STAT5 and STAT3: survival factors for prostate cancer cells -- Role of P13K-Akt and PTEN in the growth and progression of prostate cancer -- New perspectives in prediction of clinical outcome of prostate cancer; TMPRSS2-ETS gene fusion in prostate cancer -- New directions in radiation therapy of prostate cancer: brachytherapy and intensity-modulated radiation therapy -- The current knowledge of hormonal therapy in the treatment of prostate cancer -- Advances in surgical intervention of porstate cancer: comparison of the benefits and pitfalls of retropubic, perineal, and laparoscopic radical prostatectormy -- Targeted therapy trials for prostate cancer -- New perspectives on chemotherapy in prostate cancer -- Concluding remarks: the future of prostate cancer.
  • Prostate cancer. 2nd ed. 2007, Springer
    Xenograft models of human prostate cancer -- The pathology of human prostatic atrophy and inflammation -- Tissue microarrays in prostate cancer research -- Prostate (cancer) stem cells -- Cancer-host interactions: a paradigm shift brings new understanding and new opportunities -- Androgen receptor function in prostate cancer progression -- Hedgehog signaling in development and cancer -- Cholesterol, cell signaling, and prostate cancer -- Gene therapy for advanced prostate cancer -- Role of transforming growth factor-ss in immunotherapy of prostate cancer -- Biology and therapeutic basis of prostate cancer bone metastasis -- Molecular imaging: noninvasive strategies to visualize gene expression in living subjects -- Quantum dot nanotechnology for prostate cancer research -- Expression profiling of prostate cancer progression -- Somatic alterations in prostate cancer progression -- Linkage studies of prostate cancer families to identify susceptibility genes -- Somatic DNA methylation changes and prostatic carcinogenesis -- Telomeres, telomerase, chromosome stability, and prostate cancer -- Racial differences in prostate cancer mortality -- Radiotherapy for the treatment of locally advanced prostate cancer -- Recombinant antibody candidates for treatment of prostate cancer -- Differentiation agents and epigenomic therapies: an overview and potential use for prostate cancer -- Taxane-based chemotherapy for prostate cancer -- Co-targeting therapeutics for hormone refractory prostate cancer -- Intercellular targets of prostate cancer -- Novel and efficient translational clinical trial designs in advanced prostate cancer.
  • Proteases and cancer 2009, Springer Protocols
    1. Delineating protease functions during cancer development / Nesrine I. Affara, Pauline Andreu, and Lisa M. Coussens -- 2. Proteolytic systems: constructing degradomes / Gonzalo R. Ordóñez ... [et al.] -- 3. Microarrays for protease detection in tissues and cells / Kamiar Moin ... [et al.] -- 4. Positional scanning synthetic combinatorial libraries for substrate profiling / Eric L. Schneider and Charles S. Craik -- 5. Mixture-based peptide libraries for identifying protease cleavage motifs / Benjamin E. Turk -- 6. High throughput substrate phage display for protease profiling / Boris Ratnikov, Piotr Cieplak, and Jeffrey W. Smith -- 7. Imaging specific cell surface protease activity in living cells using reengineered bacterial cytotoxins / John P. Hobson ... [et al.] -- 8. Cell-based identification of natural substrates and cleavage-sites for extracellular proteases by SILAC proteomics / Magda Gioia, Leonard J. Foster, and Christopher M. Overall -- 9. Optical proteolytic beacons for in vivo detection of matrix metalloproteinase activity -- J. Oliver McIntyre and Lynn M. Matrisian -- 10. Dissecting the urokinase activation pathway using urokinase-activated anthrax toxin / Shihui Liu ... [et al.] -- 11. On-demand cleavable linkers for radioimmunotherapy / Pappanaicken R. Kumaresan, Juntao Luo, and Kit S. Lam.
  • Protein kinase C in cancer signaling and therapy: introduction and historical perspective -- Regulation of conventional and novel protein kinase C isozymes by phosphorylation and lipids -- Phorbol esters and diacylglycerol: the PKC activators -- Diacylglycerol signaling: the C1 domain, generation of DAG and termination of signals -- Regulation of PKC by protein-protein interaction in cancer -- Introduction: PKC isozymes in the control of cell function -- Regulation and function of protein kinase C signaling -- PKC and control of the cell cycle -- PKC and the control of apoptosis -- Atypical PKC's, NF-kB and inflammation -- Introduction: PKC and cancer -- Protein kinase C, p53, and DNA damage -- PKCs as mediators of the hedgehog and Wnt signaling pathways -- PKC-PKD interplay in cancer -- Transgenic mouse models to investigate functional specificity of protein kinase C isoforms in the development of squamous cell carcinoma, a nonmelanoma human skin cancer -- PKC isozymes and skin cancer -- PKC and breast cancer -- PKC and prostate cancer -- Protein kinase C and lung cancer -- Introduction [PKC isozymes as targets for cancer therapy] -- PKC and resistance to chemotherapeutic agents -- PKCd as a target for chemotherapeutic drugs -- Atypical PKCs as targets for cancer therapy.
  • Protein tyrosine kinases 2006, Springer
    Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro -- Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward -- Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.] -- Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin -- JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki -- Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville -- Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.] -- Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.] -- Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens -- Phosphoproteomics in drug discovery and development / Michel F. Moran.
  • Proton beam therapy 2013, Springer
    While radiation therapy is a mainstay of cancer treatment, traditional linear accelerators mainly use photons to irradiate cancerous tissue. Photons deposit much more energy in the surrounding normal tissue than protons. Proton beam therapy is a revolutionary alternative that deposits most of its cancer-killing energy within the area of the tumor, thereby potentially improving cure rates and reducing side effects in properly selected patients. This book guides the reader through existing evidence supporting proton beam therapy for an increasing number of patients and conditions, including pediatric, prostate, and lung cancer, mediastinal tumors, skull base tumors, conditions of the eye, and sarcomas.
  • Psycho-oncology 2014, Springer
    Psycho-oncology is a thriving discipline in cancer care, and numerous research activities have been undertaken in the endeavor to improve treatment outcomes and to gain a better understanding of the psychological consequences of cancer. This book presents and discusses the latest findings from science and practice for a broad range of psychological and social issues related to cancer and its treatments. Not only are general psychosocial impacts of cancer described, but the very common fear of progression is elucidated. The relevance of psychooncology at different stages of disease (during oncological treatment, in rehabilitation, and during palliative care) is explained, and various psychooncological interventions are illustrated. Other important topics are the experience of being a cancer survivor, who may be cured but not be healthy, the psychological burden on relatives, and gender differences in coping with cancer. Quality of life and patient-reported outcomes are also commented on since they are among the key benchmarks for successful coping with the diagnosis of cancer, its treatment, and its late effects.
  • Psychoneuroimmunology and cancer : incidence, progression, and quality of life -- Inflammation, chronic disease, and cancer : is psychological distress the common thread? -- Psychological aspects of hereditary cancer risk counseling and genetic testing -- Mastectomy to prevent breast cancer : psychosocial aspects of women's decision-making -- Decision aids in advanced cancer -- Cancer fatalism : attitudes toward screening and care -- Positive psychology perspectives across the cancer continuum : meaning, spirituality, and growth -- Stress, coping, and hope -- Religiousness and spirituality in coping with cancer -- Controversies in psycho-oncology -- Psychosocial interventions for couples coping with cancer : a systematic review -- The impact of cancer and its therapies on body image and sexuality -- Cancer caregivership -- Psychosocial interventions in cancer -- Quality of life -- Exercise for cancer patients : treatment of side effects and quality of life -- Use of the classic hallucinogen Psilocybin for treatment of existential distress associated with cancer -- The placebo and nocebo effects in cancer treatment -- Psychological factors and survivorship : a focus on post-treatment cancer survivors -- Complementary mind-body therapies in cancer -- End-of-life communication in cancer care -- The intersection between cancer and caregiver survivorship -- Resources for cancer patients -- Bringing it all together.
  • Quantitative MRI in cancer 2012, CRCnetBASE
  • Radiation oncology 2008, Springer
  • Radiation oncology 2012, Springer
    Radiation Physics --Radiobiology --Clinical Radiation Oncology --Central Nervous System Tumors --Head and Neck Cancers --Lung Cancer --Breast Cancer --Genitourinary System Cancers --Gynecological Cancers --Gastrointestinal System Cancers --Soft Tissue Sarcoma --Skin Cancer --Lymphomas and Total Body Irradiation --Pediatric Tumors --Rare Tumors and Benign Diseases.
  • Central Nervous System Tumors: Adult and Pediatric -- Skin Cancer -- Head and Neck Cancer -- Lung Cancer -- Tumors of the Mediastinum -- Breast Cancer -- Upper Gastrointestinal Cancers -- Lower Gastrointestinal Cancers -- Urinary System Cancers -- Male Genitourinary Cancer -- Gynecologic Malignancies -- Hematologic Malignancies -- Sarcoma -- Pediatric Non-central Nervous System Cancers -- Benign and Metastatic Disease.
  • Ideal for on-the-spot consultation, this pocket manual, Radiation Oncology: Management Decisions, provides easily accessible information for residents and practitioners in radiation oncology. It presents the most essential information that is immediately required in the clinical setting. The first eight chapters of the book focus on key basic concepts; the remaining 46 chapters describe treatment regimens for all cancer sites and tumor types. Includes coverage of pain and palliation, and covers all latest therapeutic techniques. This edition includes expanded information on image-guided therapy, 3D techniques, and 4D protocols. The updated cancer staging guidelines have been used throughout the manual. In addition, there is a brand-new chapter devoted to QUANTEC dosage recommendations.
  • Radiation toxicity 2006, Springer
  • Radioguided surgery 2008, Springer
    Part I. Chemistry and Physics -- Radiopharmaceuticals for Radioguided Surgery / Esteban Obenaus, Paola A. Erba, Marco Chinol, Christophe Van de Wiele and Gyozo A. Janoki, et al. -- Physical Performance Parameters of Intraoperative Probes / Carlo Chiesa, Francesca Toscano, Mario Mariani and Emilio Bombardieri -- Positron-Sensitive Probes / Schlomo Schneebaum, Richard Essner and Einat Even-Sapir -- Gamma Ray Imaging Probes for Radioguided Surgery and Site-Directed Biopsy / Francesco Scopinaro and Alessandro Soluri -- Radiation Protection in Radioguided Surgery / Edwin C. Glass and Wendy A. Waddington -- Training and Credentialing for Radioguided Surgery / Eric D. Whitman -- Part II. Sentinel Lymph Nodes -- The Anatomy and Physiology of Lymphatic Circulation / Preya Ananthakrishnan, Giuliano Mariani, Luciano Moresco and Armando E. Giuliano -- The Role of Lymph Node Staging for Clinical Decision Making in Patients with Solid Cancers / Fausto Badellino, Ilaria Pastina, Elisa Borsò, Sergio Ricci and H. William Strauss, et al. -- Sentinel Lymph Node Biopsy in Patients with Breast Cancer / Charles E. Cox, John M. Cox, Giuliano Mariani, Caren E.G. Wilkie and Laura B. White, et al. -- Sentinel Lymph Node Biopsy in Cutaneous Melanoma / Jeffrey E. Gershenwald, Roger F. Uren, Giuliano Mariani and John F. Thompson -- Dynamic Sentinel Lymph Node Biopsy in Penile Carcinoma / Simon Horenblas, Bin K. Kroon, Renato A. Valdés Olmos and Omgo E. Nieweg -- Sentinel Lymph Node Biopsy in Cancer of the Head and Neck / Luca Calabrese, David Soutar, Jochen Werner, Roberto Bruschini and Concetta De Cicco, et al. -- Sentinel Lymph Node Biopsy in Gynecologic Malignancies / Emilio Bombardieri, Marco Maccauro, Rosanna Fontanelli, Francesco Raspagliesi and Giovanni Paganelli -- Sentinel Lymph Node Biopsy in Cancers of the Gastrointestinal Tract / Yuko Kitagawa, Sukamal Saha and Masaki Kitajima --Sentinel Lymph Node Biopsy in Prostatic Cancer / Alexander Winter, Harry Vogt, Dorothea Weckermann, Rolf Harzmann and Friedhelm Wawroschek -- Radioguided Biopsy of the Sentinel Lymph Node in Patients with Non-Small Cell Lung Cancer / Giuseppe Boni, Gianpiero Manca, Franca M. A. Melfi, Marco Lucchi and Alfredo Mussi, et al. -- Sentinel Lymph Node Biopsy in Thyroid Cancer / Massimo Salvatori, Domenico Rubello, Michael J. O'Doherty, Maria Rosa Pelizzo and Giuliano Mariani -- Histopathology of Sentinel Lymph Nodes / Giuseppe Viale, Giovanni Mazzarol and Eugenio Maiorano -- Frozen Section and Imprint Cytology in Sentinel Lymph Node Biopsy for Breast Cancer / Santo V. Nicosia and Charles E. Cox -- Molecular Assessment of Sentinel Lymph Nodes / Farin Amersi, Armando E. Giuliano and Dave S.B. Hoon -- Part III. Occult Lesion Localization -- Where It All Began: The Heritage of Radioimmunoguided Surgery / Fausto Badellino, Mario Roselli, Marzio Perri, Fiorella Guadagni and Giuliano Mariani -- Radioguided Occult Lesion Localization in the Breast / Giovanni Paganelli, Concetta De Cicco, Giovanna Gatti and Alberto Luini -- Minimally Invasive Radioguided Parathyroidectomy in Primary Hyperparathyroidism / James Norman, Domenico Rubello, Armando E. Giuliano and Giuliano Mariani -- Radioguided Surgery of Neuroendocrine Tumors / Richard P. Baum, Sergio Sandrucci and Stefan Adams -- Radioguided Surgery of Solitary Pulmonary Nodules / Giuseppe Boni, Franca M. A. Melfi, Gianpiero Manca, Marco Lucchi and Alfredo Mussi, et al. -- Radioguided Surgery of Occult Lesions in Patients with Thyroid Cancer / Domenico Rubello, Massimo Salvatori, Maria Rosa Pelizzo, Giuseppe Boni and Giuliano Mariani -- Radioguided Bone Lesion Localization / Gianpiero Manca, Giuliano Mariani and Lary A. Robinson.
  • Radiopharmaceuticals 2011, CRCnetBASE
    "This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It examines the relative benefits of various radiopharmaceuticals and provides guidance on dose estimation and agent selection. Utilizing figures of merit for quantitative assessment, it covers standard medical internal radiation dose (MIRD), absorbed dose method for imaging agents, vivo methods for obtaining activity data, errors of activity estimation techniques, phantom-based and patient-based dose estimates and their associated uncertainties, and options available to clinical physicists. Supported by numerous examples from clinical trials, it discusses two and three dimensional estimation processes, including modern hybrid scanners such as SPECT/CT and PET/CT"--Provided by publisher.
  • In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an experimental therapy with a prospective control therapy.
  • Epidemiology and databases -- Rare and uncommon gynecological cancers: a clinical guide -- The contribution of diagnostic imaging in rare gynecological malignancies -- Mucinous cancers: ovary -- Pseudomyxoma peritonei -- Ovarian clear cell carcinoma -- Clear cell carcinoma of the ovary -- The continuum of serious ovarian tumors of low malignant potential and low-grade serous carcinoma of the ovary -- Sex cord-stromal tumors -- Squamous cell carcinomas arising from dermoids -- Ovarian carcinosarcomas -- Small cell and neuroendocrine cancers of the ovary -- Primary ovarian carcinoids and neuro-endocrine tumors including struma ovarii -- Reed uterine carcinosarcomas -- Leiomyosarcomas of uterus -- Mucinous tumors of the uterine corpus -- Clear cell cancers of uterus -- Small cell and neuroendocrine cancers of the cervix -- Primary malignant melanoma of the vulva and vagina -- Gynecologic cancers in pregnancy: guidelines of an international consensus meeting.
  • Razoxane and dexrazoxane 2010, Springer
  • Re-irradiation 2011, Springer
  • Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super.
  • Rectal cancer 2013, Springer
  • Rectal cancer 2005, Springer
  • Rectal cancer 2010, Springer
  • Rectal cancer treatment 2005, Springer
  • Regional cancer therapy 2007, Springer
  • Renal cancer 2013, Springer
  • Renal cell cancer 2008, Springer
  • Renal cell carcinoma 2012, Springer
    Pt. 1. Biology of renal cell carcinoma -- pt. 2. Current and future molecular targets for RCC.
  • Renal cell carcinoma 2013, Springer
  • Targeted therapy for metastatic renal call carcinoma: overview -- Molecular genetics in inherited renal cell carcinoma: identification of targets in the hereditary syndromes -- Molecular targets in renal tumors: pathologic assessment -- Interferons and interleukin-2: molecular basis of activity and therapeutic results -- The molecular biology of kidney cancer and its clinical translation into treatment strategies -- VEGF: biologic aspects and clinical approaches -- VEGF and PDGF receptors: biologic relevance and clinical approaches to inhibition -- Sunitinib and axitinib in renal cell carcinoma -- Sorafenib in renal cell carcinoma -- Additional tyrosine kinase inhibitors in renal cell carcinoma -- Integrin [alpha]5[beta]1 as a novel therapeutic target in renal cancer -- Carbonic anhydrase IX: biology and clinical approaches -- Monoclonal antibody G250 recognizing carbonic anhydrase IX in renal cell carcinoma: biological and clinical studies -- Chemokines in renal cell carcinoma: implications for tumor angiogenesis and metastasis -- P13K/Akt/mTOR pathway: a growth and proliferation pathway -- EGFR and HER2: relevance in renal cell carcinoma -- Proteasome-NF[kappa]B signaling pathway: relevance in RCC -- The role of hepatocyte growth factor pathway signaling in renal cell carcinoma -- Smac/DIABLO: a proapoptotic molecular target in renal cell cancer -- EphA2: a novel target in renal cell carcinoma -- Restoring host antitumoral immunity: how coregulatory molecules are changing the approach to the management of renal cell carcinoma -- The role of gangliosides in renal cell carcinoma -- Tumour necrosis factor: misnomer and therapeutic target -- Molecular markers for predicting prognosis of renal cell carcinoma -- Adjuvant therapy for renal cell carcinoma: targeted approaches.
  • Principles of cancer treatment: impact on reproduction -- Fertility preservation options for females -- Options for fertility preservation in men and boys with cancer -- Contraception and cancer treatment in young persons -- Sexual health during cancer treatment -- Unique reproductive concerns of young women with breast cancer -- Pregnancy and cancer -- Preimplantation genetic diagnosis for hereditary cancers -- Non-traditional family building planning -- Parenting with cancer I: developmental perspective, communication, and coping -- Parenting with cancer II: parenting at different stages of illness -- Pediatric oncology and reproductive health -- Institutional approaches to implementing fertility preservation for cancer patients -- Patient provider communication and reproductive health -- Fertility preservation in cancer patients: ethical considerations -- Legal issue and of assisted reproductive technologies.
  • Retinoblastoma 2010, Springer
  • Rho GTPases in cancer 2010, Springer
  • RNA and cancer 2013, Springer
    Coupling Between Transcription and Alternative Splicing /Ignacio E. Schor, Luciana I. Gómez Acuña, Alberto R. Kornblihtt --Detection of Alternatively Spliced or Processed RNAs in Cancer Using Oligonucleotide Microarray /Marieta Gencheva ... [et al.] --Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing /Lulzim Shkreta ... [et al.] --Alternative Splicing of Tumor Suppressors and Oncogenes /Claudia Ghigna, Silvano Riva, Giuseppe Biamonti --MicroRNAs in Cancer /Jianzhong Jeff Xi --The Perinucleolar Compartment: RNA Metabolism and Cancer /John T. Norton, Sui Huang --Regulation of ARE-mRNA Stability by Cellular Signaling: Implications for Human Cancer /Christian Kroun Damgaard, Jens Lykke-Andersen --Alternative Pre-mRNA Splicing, Cell Death, and Cancer /Kong Ruirui ... [et al.] --Oligonucleotide Therapeutics in Cancer /Jing Wan, John A. Bauman, Maria Anna Graziewicz, Peter Sazani --Clinical Perspective on Chemo-Resistance and the Role of RNA Processing /Nancy L. Krett, Shuo Ma, Steven T. Rosen.
  • Interdiction of sphingolipid metabolism to improve standard cancer therapies -- Diverse functions of ceramide in cancer cell death and proliferation -- Cermaide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance -- Use of acid sphingomyelinase for cancer therapy -- Hypoxia therapeuric resistance and sphingosine 1-phosphate -- Therapeutic potential of targeting SK1 in human cancers -- Sphinogosine kinase 1 in cancer -- Natural products as platforms for the design of sphingolipid-related anticancer agents.
  • Ch. 1. Anatomy and physiologic morphology -- Ch. 2. Abnormalities of mammary growth and development -- Ch. 3. Inflammatory and reactive tumors -- Ch. 4. Specific infections -- Ch. 5. Papilloma and related benign tumors -- Ch. 6. Myoepithelial neoplasms -- Ch. 7. Adenosis and microglandular adenosis -- Ch. 8. Fibroepithelial neoplasms -- Ch. 9. Ductal hyperplasia: ordinary and atypical -- Ch. 10. Precancerous breast disease: epidemiologic, pathologic, and clinical considerations -- Ch. 11. In Situ (intraepithelial) carcinoma: an overview -- Ch. 12. Staging of breast carcinoma -- Ch. 13. Intraductal carcinoma -- Ch. 14. Invasive duct carcinoma: assessment of prognosis, morphologic prognostic markers, and tumor growth rate -- Ch. 15. Tubular carcinoma -- Ch. 16. Papillary carcinoma -- Ch. 17. Medullary carcinoma -- Ch. 18. Carcinoma with metaplasia -- Ch. 19. Squamous carcinoma -- Ch. 20. Mucinous carcinoma -- Ch. 21. Apocrine carcinoma -- Ch. 22. Mammary carcinoma with endocrine features -- Ch. 23. Small cell (oat cell) carcinoma -- Ch. 24. Secretory carcinoma -- Ch. 25. Mammary carcinoma with osteoclast-like.giant cells -- Ch. 26. Cystic hypersecretory carcinoma and cystic hypersecretory hyperplasia -- Ch. 27. Adenoid cystic carcinoma -- Ch. 28. Cribriform carcinoma -- Ch. 29. Lipid-rich carcinoma -- Ch. 30. Gylcogen-rich carcinoma -- Ch. 31. Invasive micropapillary carcinoma -- Ch. 32. Paget's disease of the nipple -- Ch. 33. Lobular carcinoma In Situ and atypical lobular hyperplasia -- Ch. 34. Invasive lobular carcinoma -- Ch. 35. Unusual clinical presentations of carcinoma -- Ch. 36. Metastases in the breast from nonmammary malignant neoplasms -- Ch. 37. Benign proliferative lesions of the male breast -- Ch. 38. Carcinoma of the male breast -- Ch. 39. Breast tumors in children -- Ch. 40. Benign mesenchymal neoplasms -- Ch. 41. Sarcoma -- Ch. 42. Lymphoid and hematopoietic tumors -- Ch. 43. Pathologic effects of therapy -- Ch. 44. Cutaneous neoplasms -- Ch. 45. The pathology of axillary and intramammary lymph nodes -- Ch. 46. Pathologic examination of breast and lymph node specimens.
  • Anatomy and physiological morphology --Abnormalities of mammary growth and development --Inflammatory and reactive tumors --Specific infections --Papilloma and related benign tumors --Myoepithelial neoplasms --Adenosis and microglandular adenosis --Fibroepithelial neoplasms --Ductal hyperplasia: usual and atypical --Precancerous breast disease: epidemiological, pathological, and clinical considerations --Intraductal carcinoma --Invasive duct carcinoma: assessment of prognosis, morphologic prognostic markers, and tumor growth rate --Tubular carcinoma --Papillary carcinoma --Medullary carcinoma --Carcinoma with metaplasia --Squamous carcinoma --Mucinous carcinoma --Apocrine carcinoma --Mammary carcinomas with endocrine features --Small cell (oat cell) carcinoma --Secretory carcinoma --Mammary carcinoma with osteoclast-like giant cells --Cystic hypersecretory carcinoma and cystic hypersecretory hyperplasia --Adenoid cystic carcinoma --Cribriform carcinoma --Lipid-rich carcinoma --Glycogen-rich carcinoma --Invasive micropapillary carcinoma --Paget's disease of the nipple --Lobular carcinoma in situ and atypical lobular hyperplasia --Invasive lobular carcinoma --Unusual clinical presentations of carcinoma --Metastases in the breast from nonmammary malignant neoplasms --Benign proliferative lesions of the male breast --Carcinoma of the male breast --Breast tumors of children --Benign mesenchymal neoplasms --Sarcoma --Lymphoid and hematopoietic tumors --Pathologic effects of therapy --Cutaneous neoplasms --The pathology of axillary and intramammary lymph nodes --Pathologic examination of breast and lymph node specimens, including sentinel lympth nodes.
  • Selfish cell 2008, Springer
  • Serous effusions 2012, Springer
  • Sexual dysfunction presents a major challenge to physicians who take on the task of treating men with prostate cancer. While curing the disease and saving a life is paramount, improving technologies and therapies offer skilled surgeons and clinical oncologists the opportunity to eradicate the disease without compromising sexual function. In Sexual Function of the Prostate Cancer Patient, John Mulhall and a panel of internationally recognized experts on prostate cancer and sexual function assess in detail the current state of prostate cancer treatment. The authors offer a broad overview of the pathophysiology and treatment of erectile dysfunction in men with prostate cancer, reviewing the latest findings regarding erection-sparing radiation therapy and sexual function outcomes after laparascopic and robotic prostatectomy. Additional chapters discuss intra-operative maneuvers to minimize post-operative erectile dysfunction and pharmacologic penile preservation and rehabilitation. Timely and authoritative, Sexual Function in the Prostate Cancer Patient is a highly readable guide to preserving post-prostate cancer sexual function that no urologist or radiation and medical oncologist should be without.
  • Shaped-beam radiosurgery 2011, Springer
  • "The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published, we take comprehensive review in regard with the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. Specifically, the initial stage of tumor metastasis will be highlighted. The complex tumor microenvironment accumulate a lot of growth factors, inflammatory cytokines and extracellular matrix which may turn into a group of potent metastatic factors. An integrated and sustained signaling induced by these metastatic factors may trigger EMT, migration and invasion of primary tumor into surround tissue. Blockade of these signal pathways is the most effective approach for prevention of tumor metastasis. A lot of clinical trials are under way for this purpose and the outcome are promising. The expert reviews compiled in this book may encourage the researcher in this exciting field for future study."--Back cover
  • Signs in MR-mammography 2008, Springer
  • Skin Cancer 2014, Springer
  • Skin cancer 2011, Springer
  • Skin cancer management 2010, Springer
    Biopsy techniques and interpretation / Deborah F. MacFarlane and Ronald P. Rapini -- Topical therapies for nonmelanoma skin cancers / Abel Torres and Tejas Desai -- Chemical peels for precancerous skin lesions / Gary D. Monheit and Chad L. Prather -- Photodynamic therapy / Nathalie C. Zeitouni, Allan Oseroff, and David J. Najarian -- Intralesional and perilesional treatment of skin cancers / Christopher J. Arpey, Nicole M. Annest, Stephen B. Tucker, Ronald P. Rapini, and Deborah F. MacFarlane -- Electrodesiccation and curettage / Gloria F. Graham -- Cryosurgery / Gloria F. Graham -- Optimizing surgical outcomes / Thomas Stasko and Amy Ross -- Anesthesia / Susannah L. Collier and George J. Hruza -- Excision techniques, staples, and sutures / Mollie A. MacCormack -- Mohs surgery / Desiree Ratner and Jennifer L. MacGregor -- Cutaneous flaps / Tatyana Humphreys -- Techniques in skin grafting / Deborah F. MacFarlane -- Nail surgery and malignant tumors of the nail unit / Deborah F. MacFarlane and Richard K. Scher -- Practical management of melanoma / Mark F. Naylor -- Skin cancer in skin of color / Brooke A. Jackson -- Management of skin cancers in solid organ transplant recipients / John Carucci and Dariush Moussai -- Imaging of head and neck skin cancer / Komal Shah, Jane Onufer, and Deborah F. MacFarlane -- Radiation oncology in skin cancer treatment / Susan L. McGovern and Matthew T. Ballo -- When to refer out / Daniel M. Siegel, Laura T. Cepeda, and Deborah F. MacFarlane -- Chemoprevention of skin cancer / Fiona Zwald and David Lambert.
  • Protein kinase inhibitors -- Imatinib mesylate -- Erlotinib -- Axitinib -- Lapatinib -- Sorafenib -- Sunitinib -- Dasatinib -- Nilotinib -- Bosutinib -- Epigenetic modifiers -- Decitabine -- 5-Azacytidine/Azacitidine -- Cell cycle inhibitors -- Bortezomib -- Temsirolimus -- Danusertib (formerly PHA-739358): a novel combined pan-aurora kinases and third generation Bcr-Abl tyrosine kinase inhibitor -- BI_2536: targeting the mitotic kinase polo-like kinase 1 (Plk1) -- Other novel agents -- Imetelstat (GRN163L): Telomerase-based cancer therapy -- GDC-0449: targeting the hedgehog signaling pathway.
  • Sphingolipids in disease 2013, Springer
    Sphingolipids in Cancer.Sphingosine Kinase/Sphingosine 1-Phosphate Signaling in Cancer Therapeutics and Drug Resistance /Shanmugam Panneer Selvam, Besim Ogretmen --Using ASMase Knockout Mice to Model Human Diseases /Guoqiang Hua, Richard Kolesnick --New Perspectives on the Role of Sphingosine 1-Phosphate in Cancer /Susan Pyne, Nigel J. Pyne --Sphingolipids and Response to Chemotherapy /Marie-Thérèse Dimanche-Boitrel, Amélie Rebillard --Lung Cancer and Lung Injury: The Dual Role of Ceramide /Tzipora Goldkorn, Samuel Chung, Simone Filosto --Sphingolipids' Role in Radiotherapy for Prostate Cancer /Carla Hajj, Adriana Haimovitz-Friedman --Sphingolipids in Cardio-Reno-vascular Diseases.Sphingolipid Metabolism and Atherosclerosis /Xian-Cheng Jiang, Jing Liu --Cardiovascular Effects of Sphingosine-1-Phosphate (S1P) /Bodo Levkau --Cross Talk Between Ceramide and Redox Signaling: Implications for Endothelial Dysfunction and Renal Disease /Pin-Lan Li, Yang Zhang --Sphingolipids in Inflammation, Infection and Lung Diseases.Sphingolipids in Lung Endothelial Biology and Regulation of Vascular Integrity /Taimur Abbasi, Joe G. N. Garcia --Sphingolipids in Acute Lung Injury /Stefan Uhlig, Yang Yang --The Involvement of Sphingolipids in Chronic Obstructive Pulmonary Diseases /Irina Petrache, Daniela N. Petrusca --Ceramide in Cystic Fibrosis /Heike Grassmé, Joachim Riethmüller, Erich Gulbins --Regulation of the Sphingosine Kinase/Sphingosine 1-Phosphate Pathway /K. Alexa Orr Gandy, Lina M. Obeid --Bacterial Infections and Ceramide /Heike Grassmé, Katrin Anne Becker --Viral Infections and Sphingolipids /Jürgen Schneider-Schaulies, Sibylle Schneider-Schaulies --Ceramide in Plasma Membrane Repair /Annette Draeger, Eduard B. Babiychuk --Sphingolipids and Inflammatory Diseases of the Skin /Burkhard Kleuser, Lukasz Japtok --Sphingolipids in Obesity, Type 2 Diabetes, and Metabolic Disease /S. B. Russo, J. S. Ross, L. A. Cowart --Sphingolipids in Neuro-psychiatry and Muscle Diseases.Neuronal Forms of Gaucher Disease /Einat B. Vitner, Anthony H. Futerman Sphingolipids in Neuroinflammation /Laura Davies, Klaus Fassbender, Silke Walter --Sphingolipids in Psychiatric Disorders and Pain Syndromes /C. Mühle, M. Reichel, E. Gulbins, J. Kornhuber --Role of Sphingosine 1-Phosphate in Skeletal Muscle Cell Biology /Paola Bruni, Chiara Donati.
  • Part 1. Bone marrow-derived stem cells -- Part 2. Embryonic stem cells -- Part 3. Cancer stem cells.
  • Introduction /Simon S. Lo, Bin S. Teh, Jiade J. Lu and Tracey E. Schefter --Historical Development of Stereotactic Ablative Radiotherapy /Timothy D. Solberg, Robert L. Siddon and Brian Kavanagh --CyberKnife System /Jun Yang, John P. Lamond, Jing Feng, Xiaodong Wu and Rachelle Lanciano, et al. --Novalis and Varian Systems /Isaac I. Rosen and Ramiro Pino --Helical TomoTherapy System /Whitney Warren, Walter H. Grant III and Bin S. Teh --Elekta System /Julian R. Perks, Megan E. Daly, David Schlesinger and Stanley H. Benedict --Treatment Planning for Stereotactic Body Radiation Therapy /Moyed Miften, Shiva K. Das, Indrin J. Chetty and David Westerly --Launching a Stereotactic Body Radiation Therapy Program /Michael Lamba --Radiobiology of Stereotactic Body Radiation Therapy/Stereotactic Ablative Radiotherapy /Michael D. Story, Chaitanya Nirodi and Clinton Park --Primary Lung Cancer /Joe Y. Chang, Shervin M. Shirvani, Billy W. Loo Jr., John P. Lamond and Ben J. Slotman, et al. --Primary Liver Cancer /Higinia R. Cárdenes and Foster Lasley --Prostate Cancer /Hiromichi Ishiyama, Alan Katz, Angel I. Blanco, Jose Hinojosa and Simon S. Lo, et al. --Renal Cell Carcinoma /Bin S. Teh, Hiromichi Ishiyama, Angel I. Blanco, Lee E. Ponsky and Simon S. Lo, et al. --Gynecologic Cancer /Charles A. Kunos, Jeffrey Fabien, Yuxia Zhang, James Brindle and Nina A. Mayr --Pancreatic Cancer /A. Yuriko Minn, Daniel T. Chang and Albert C. Koong --Benign and Malignant Primary Spinal Tumors /Brett Cox, Iris C. Gibbs and Yoshiya Yamada --Non-Skull Base Head and Neck Cancer /Farzan Siddiqui, David Raben, Sue S. Yom, Jiade J. Lu and Min Yao --Skull Base Head and Neck Cancer /Sue S. Yom, David Raben, Farzan Siddiqui, Jiade J. Lu and Min Yao --Lung Metastasis /Neha Amin, Tracey E. Schefter, Paul Okunieff, Brian Kavanagh and Michael T. Milano --Liver Metastasis /Michelle Stinauer, Rachelle Lanciano, Tracey E. Schefter, Brian Kavanagh and Julie A. Carlson, et al. --Adrenal Metastasis /Mirna Abboud, Simon S. Lo, Arnold C. Paulino, Daniel E. Lehane and Bin S. Teh --Histology-Specific Metastasis /Michael T. Milano and Joseph K. Salama --Bone Metastasis /Mirna Abboud, Arnold C. Paulino, B. S. Teh, Simon S. Lo and Rex Marco --Spinal Metastasis /Simon S. Lo, Andrew E. Sloan, Mitchell Machtay, Bin S. Teh and Arjun Sahgal, et al. --Reported Toxicities Associated with Stereotactic Body Radiation Therapy /Simon S. Lo, Arjun Sahgal, Charles A. Kunos, Bin S. Teh and Min Yao, et al. --Normal Tissue Constraints /Simon S. Lo, Arjun Sahgal, Lijun Ma, Ben J. Slotman and Zhibin Huang, et al. --Erratum: Primary Liver Cancer /Higinia R. Cárdenes and Foster Lasley --Erratum: Bone Metastasis /Mirna Abboud, Arnold C. Paulino, B. S. Teh, Simon S. Lo and Rex Marco.
  • Targeting oncogenic drivers / Zhao, Y.; Adjei, A.A. (Buffalo, N.Y.) -- Successes and limitations of targeted cancer therapy in breast cancer / Curigliano, G.; Criscitiello, C. (Milan) -- Successes and limitations of targeted cancer therapy in colon cancer / Khne, C.-H. (Oldenburg) -- Successes and limitations of targeted cancer therapy in gastrointestinal stromal tumors / Casali, P.G. (Milano) -- Successes and limitations of targeted cancer therapy in lung cancer / Suda, K. (Osaka-Sayama/Fukuoka); Mitsudomi, T. (Osaka-Sayama) -- Successes and limitations of targeted cancer therapy in melanoma / Romano, R.; Michielin, O. (Lausanne) -- / successes and limitations of targeted cancer therapy in ovarian cancer / Damia, G. (Milan); Sessa, C. (Bellinzona) -- Successes and limitations of targeted therapies in renal cell carcinoma / Pracht, M.; Berthold, D. (Lausanne).
  • Suicide gene therapy 2004, Springer Protocols
  • Supportive oncology 2011, ScienceDirect
  • History of cerebellopontine angle surgery -- Microsurgical anatomy of the cerebellopontine angle by the retrosigmoid approach -- Neuropathology of the cerebellopontine angle and its surroundings -- Approaches to the cerebellopontine angle -- Vestibular schwannomas -- Neurofibromatosis Type 2 and other bilateral cerebellopontine angle tumors -- Meningiomas -- Cerebellopontine angle epidermoids -- Nonvestibular schwannomas -- Jugular foramen tumors -- Other cerebellopontine angle tumors -- Management of facial palsy.
  • Surgery of spinal tumors 2007, Springer
    History -- Anatomy -- Intramedullary tumors -- Extramedullary tumors -- Epidural tumors.
  • Historical Background or De quibusdam Renum glandulis: The History of Adrenals /Donatella Lippi --Surgical Anatomy /Celestino Pio Lombardi, Carmela De Crea, Francesco Pennestri and Marco Raffaelli --Pathology /Gabriella Nesi and Raffaella Santi --Diagnosis and Clinical Pictures /Gabriele Parenti and Massimo Mannelli --Imaging /Massimo Falchini and Vittoria Rufini --Perioperative Management /Tommaso Borracci, Luca Vitali, Lorenzo Antonuzzo, Liliana Sollazzi and Valter Perilli, et al. --General Principles of Adrenal Surgery /Robin M. Cisco and Quan-Yang Duh --Instrumentation and High-Technology /Francesco Corcione, Valentina Brancato and Michele Giuseppe Iovino --Right Flank Trans-Abdominal Laparoscopic Adrenalectomy /Carlo Bergamini and Andrea Valeri --Left Flank Trans-Abdominal Laparoscopic Adrenalectomy /Celestino Pio Lombardi, Marco Raffaelli, Carmela De Crea, Francesco Pennestri and Rocco Bellantone --Posterior Retroperitoneoscopic Adrenalectomy /Rocco Bellantone, Marco Raffaelli, Carmela De Crea, Luigi Oragano and Celestino Pio Lombardi --Open Adrenalectomy /Giorgio De Toma, Andrea Polistena and Giuseppe Cavallaro --Other Techniques of Video-Assisted and Open Adrenalectomies /Rocco Bellantone, Francesco Corcione, Celestino Pio Lombardi, Marco Raffaelli and Carmela De Crea, et al. --Outcome of Adrenal Surgery /Andrea Valeri and Carlo Bergamini.
  • Imaging of endocrine and neuroendocrine tumors -- Fine needle aspiration cytology of endocrine tumors -- Fine needle aspiration cytology of neuroendocrine tumors arising in non-endocrine organs -- Tumors of the pituitary gland -- Tumors of thyroid gland : non-C cell tumors -- Tumors of the thyroid gland (C-cells) -- Tumors of parathyroid gland -- Tumors of the adrenal cortex -- Tumors of the adrenal medulla and extra-adrenal paraganglia -- Endocrine tumors of the lung and upper airways -- Neuroendocrine tumors of the pancreas -- Neuroendocrine tumors of the gastrointestinal tract -- Neuroendocrine tumours of the breast -- Neuroendocrine tumors of female genital tract -- Neuroendocrine tumors of prostate, urinary bladder, and kidney -- Neuroendocrine tumors of other miscellaneous sites : thymus and skin -- Endocrine tumors and tumor-like lesions of infancy, childhood, and adolescents and inherited tumor syndromes -- Application of molecular diagnosis techniques in the diagnosis and management of endocrine tumors.
  • Overview / Cindy L. Schwartz ... [et al.] -- Algorithms of late effects by disease / Cindy L. Schwartz, Wendy L. Hobbie, Louis S. constine -- Facilitating assessment of late effects by organ system / Cindy L. Schwartz, Wendy L. Hobbie, Louis S. Constine -- Central nervous system effects / Nina S. Kadan-Lottick, Joseph P. Neglia -- Neuroendocrine complications of cancer therapy / Wing Leung, Susan R. Rose, Thomas E. Merchant -- Ocular complications due to cancer treatment / Michael Ober, Camille A. Servodidio, David Abramson -- Head and neck / Arnold C. Paulino, Mary Koshy, Della Howell -- Adverse effects of cancer treatment on hearing / Wendy Landier, Thomas E. Merchant -- The thyroid gland / Tithi Biswas, Louis S. constine, Cindy L. Schwartz -- Cardiovascular effects of cancer therapy / M. Jacob Adams ... [et al.] --Pulmonary effects of antineoplastic therapy / Andrea S. Hinkle, Cindy Proukou, Yuhchyau Chen -- Late gastrointestinal and hepatic effects / M.M. Hudson -- The ovary / Debra L. Friedman -- The testes / Jill P. Ginsberg, Amit Maity -- Genitourinary / Lawrence Marks, Nicole Larrier -- Musculoskeletal, integument, breast / Robert B. Marcus, Jr. ... [et al.] -- Hematopoietic stem cell transplantation / Nancy Bunin, constance DiDomenico, Virginia Guzikowski -- Second malignancies following treatment for childhood cancer / Barbara Anne Hieb, Susan K. Ogle, Anna T. Meadows -- Psychological aspects of long-term survivorship / Mary T. Rourke, Anne E. Kazak -- Legal issues / Barbara Hoffman -- Methodological issues in the study of survivors of childhood cancer / Ann C. Mertens, Yutaka Yasui -- Transition issues / Kevin C. Oeffinger, Debra A. Eshelman.
  • T-cell lymphomas 2013, Springer
  • v. 2 Springer Protocols
    v. 1. Emerging strategies for targets and biomarker discovery -- v. 2. Emerging molecular targets and treatment options.
  • Targeted cancer therapy 2008, Springer
    Perspectives : bench to bedside and back / Jennifer Wheler and Razelle Kurzrock -- Targeted therapy in acute myelogenous leukemia / Elihu Estey -- Targeted therapy in breast cancer / Barbara S. Craft and Stacy Moulder -- Targeted therapy in chronic lymphocytic leukemia / Apostolia-Maria Tsimberidou and Michael J. Keating -- Targeted therapy in chronic myeloid leukemia / Elias Jabbour, Jorge Cortes, and Hagop Kantarjian -- Targeted therapy in colorectal cancer / Scott Kopetz -- Targeted therapy in non-small cell lung cancer / David J. Stewart -- Targeted therapy in lymphoma / Amanda Wedgwood and Anas Younes -- Targeted therapy in melanoma / Michael Davies, Sunil Patel, and Kevin B. Kim -- Targeted therapy in multiple myeloma / Yuhong Zhou, Raymond Alexanian, and Micael Wang -- Targeted therapy in myelodysplastic syndrome / Alfonso Quintás-Cardama ... [et al.] -- Targeted therapy in epithelial ovarian cancer / Maurie Markman -- Targeted drug therapy in pancreatic cancer / Don L. Gibbons, Robert A. Wolff, and Gauri Varadhachary -- Targeted therapy in prostate cancer / Amado J. Zurita, John F. Ward, and Jeri Kim -- Targeted therapy in renal cell carcinoma / Eric Jonasch and Nizar Tannir -- Targeted therapy of Sarcoma / Joseph Ludwig and Jonathan C. Trent -- Targeted and functional imaging / Vikas Kundra, Dawid Schellingerhout, and Edward F. Jackson -- Combining targeted therapies / David Hong and Lakshmi Chintala -- Drug development in cancer medicine : challenges for targeted approaches / Luis H. Camacho -- Toward personalized therapy for cancer / Sarah J. Welsh and Garth Powis.
  • Introduction: the rationale for the development of targeted drugs in cancer therapy -- Identifying critical signaling molecules for the treatment of cancer -- Tyrosine kinase inhibitors and cancer therapy -- Targeting ERBB receptors in cancer -- Inhibition of the IGF-I receptor for treatment of cancer. Kinase inhibitors and monoclonal anitbodies as alternative approaches -- Inhibition of the TGF-B signaling pathway in tumor cells -- The mammalian target of rapamycin kinase and tumor growth inhibtition -- The ras signalling pathway as a target in cancer therapy -- The mitogen-activated protein kinase pathway for molecular-targeted cancer treatment -- Clinical relevance of tareted interference with Src-mediated signal transduction events.
  • Targeted therapies 2011, Springer
    Resistance to Targeted Therapies As a Result of Mutation(s) in the Target / Alexis B. Cortot and Pasi A. Jänne -- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies / Daniel Gioeli -- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry / Jason R. Neil and Forest M. White -- Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications / Julia D. Wulfkuhle, Menawar Khalil, Joseph C. Watson, Lance A. Liotta and Emanuel F. Petricoin -- Using Phosphoflow® to Study Signaling Events of Subpopulations Resistant to Current Therapies / Omar D. Perez -- Mathematical and Computational Models in Cancer / Sudhir Chowbina, Kevin A. Janes, Shayn M. Peirce and Jason A. Papin -- Somatic Evolution of Acquired Drug Resistance in Cancer / John W. Pepper -- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer / Edward Gunther -- microRNA: A Potential Therapy Able to Target Multiple Cancer Pathways / Benjamin Kefas and Benjamin W. Purow -- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance / Yun Dai and Steven Grant.
  • Telomerase inhibition 2007, Springer Protocols
    Methods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.
  • "Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. 4 of cover.
  • Thyroid cancer 2012, Springer
  • Thyroid cancer 2011, CRCnetBASE
    "Thyroid cancer evaluation and treatment has enjoyed very little evolution in comparison with other disease management strategies. The standard treatment algorithms for thyroid cancer have varied only in response to major, though infrequent, biotechnological innovations. These resultant algorithm node insertions produced paradigm changes, but there has been little to advance the care of the patient with advanced thyroid cancer--until very recently. Perhaps the reasons for a relative lack of interest and scientific progress are the overwhelming likelihood of benignity among thyroid nodules, the overwhelmingly favorable clinical outcome even if a patient has thyroid cancer, and the overwhelming long time required for clinical follow-up of these cancer patients. Unfortunately, the problem now is that we may be overmanaging low-risk patients, and we have not achieved the clinical responses we would have liked with high-risk patients"--Provided by publisher.
  • Thyroid cancer. 2nd ed. 2005, Springer
  • Thyroid cancer. 2nd ed. 2006, Springer
  • Thyroid neoplasms 2005, ScienceDirect
    Gene rearrangements in thryoid cancer -- Molecular markers of thyroid nodules -- Ultrasound in the diagnosis and management of thyroid cancer -- Controversies in the use of radioiodine for remnant ablation and therapy of thyroid carcinoma -- Thyroglobulin measurements in thryoid cancer evaluation and surveillance -- The role of fluoro-deoxy glucose (FDG) positron emission tomorgraphy (PET) in the management of differentiated thyroid cancer -- Preclinical studies of chemotherapy for undifferentiated thyroid carcinoma -- Medullary thyroid carcinoma -- Thyroid neoplasms in children and adolescents.
  • Phylogeny of the TRAF/math domain / Juan M. Zapata, Vanesa Martínez-García, and Sophie Lefebvre -- TRAF1 and its biological functions / Soo Young Lee and Yongwon Choi -- Physiological roles and mechanisms of signaling by TRAF2 and TRAF5 / Ping-Yee Billie Au and Wen-Chen Yeh -- TRAF3 and its biological function / Jeannie Q. He ... [et al.] -- TRAF4, the unique family member / Valérie Kedinger and Marie-Christine Rio -- Characteristics and biological functions of TRAF6 / Jun-ichiro Inoue, Jin Gohda and Taishin Akiyama -- Ubiquitination and TRAF signaling / Gabriel Pineda, Chee-Kwee Ea and Zhijian J. Chen -- Structural revelations of TRAF2 function in TNF receptor signaling pathway / Jee Y. Chung ... [et al.] -- Protein-protein interactions in TRAF3 / Kathryn R. Ely, Ramadurgam Kodandapani and ShuangDing Wu -- Molecular basis for the unique specificity of TRAF6 / Jee Y. Chung ... [et al.] --TRAF proteins in CD40 signaling / Gail A. Bishop ... [et al.] -- TRAFs in rank signaling / Bryant G. Darnay ... [et al.] -- The LT[beta]R signaling pathway / Paula S. Norris and Carl F. Ware -- LMP1 trafficking activates growth and survival pathways / Vishal Soni, Ellen Cahir-McFarland and Elliott Kieff -- Targeting TRAFs for therapeutic intervention / Juan M. Zapata, Sophie Lefebvre and John C. Reed.
  • TNM atlas. 5th ed. / 2004, Springer
  • v. 2 2008 Springer
    v. 1. Basic and clinical biology -- v. 2. Cancer treatment and therapy.
  • "With the advent of computer technology and medical imaging, treatment planning in radiation oncology has evolved from a way of devising beam arrangements to a sophisticated process whereby imaging scanners are used to define target volume, simulators are used to outline treatment volume, and computers are used to select optimal beam arrangements for treatment. As such, this book is designed to provide a comprehensive discussion of the clinical, physical, and technical aspects of treatment planning. The intent of Treatment Planning in Radiation Oncology is to review these methodologies and present a contemporary version of the treatment planning process"--Provided by publisher.
  • Tumeurs malignes rares 2010, Springer
  • Tumor ablation 2013, Springer
  • Tumor angiogenesis 2008, Springer
  • Tumor microenvironment 2010, Springer
  • The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.
  • Perspectives on the history and evolution of tumor models -- Murine L1210 and P388 leukemias -- Transplantable syngeneic rodent tumors: solid tumors in mice -- B16 murine melanoma: historical perspective on the development of a solid tumor model -- Human tumor xenograft efficacy models -- Imaging the steps of metastasis at the macro and cellular level with fluorescent proteins in real time -- Patient-derived tumor models and explants -- The pediatric preclinical testing program -- Imaging efficacy in tumor models -- Mammary cancer in rats -- Animal models of melanoma -- Experimental animal models for investigating renal cell carcinoma pathogenesis and preclinical therapeutic approaches -- Animal models of mesothelioma -- The use of mouse models to study leukemia/lymphoma and assess therapeutic approaches -- Spontaneous companion animal (pet) cancers -- Genetically engineered mouse models of pancreatic ductal adenocarcinoma -- Transgenic adenocarcinoma of the mouse prostate: a validated model for the identification and characterization of molecular targets and the evaluation of therapeutic agents -- The utility of transgenic mouse models for cancer prevention research -- Models for evaluation of targeted therapies of invasive and metastatic disease -- Animal models of toxicities caused by anti-neoplastic therapy -- Bone marrow as a critical normal tissue that limits drug dose/exposure in preclinical models and the clinic -- Anesthetic considerations for the study of murine tumor models -- Preclinical tumor response end points -- Tumor cell survival -- Apoptosis in vivo -- Transparent window models and intravital microscopy: imaging gene expression, physiological function and therapeutic effects in tumors.
  • Tumor necrosis factor 2004, Springer Protocols
  • Tumor neurosurgery 2006, Springer
    I. Investigations -- Neurophysiology / Allen E. Waziri, Derek A. Taggard and Vincent C. Traynelis -- Neuroradiology and Ultrasound / David G. Hughes and Roger A. Chisholm -- Neuropathology / Cheng-Mei Shaw and Ellsworth C. Alvord -- II. Perioperative Care -- Neuroanesthesia / Maryke A. Kraayenbrink and Gregory R. McAnulty -- Neurosurgical Intensive Care / Tessa L. Whitton and Arthur M. Lam -- III. Techniques -- Neuroendoscopy / Jonathan Punt -- Principles and Practice of Image-guided Neurosurgery / Kristian Aquilina, Philip Edwards and Anthony Strong -- Stereotactic Radiosurgery / Andras A. Kemeny, Matthias W. R. Radatz and Jeremy G. Rowe -- IV. Tumors -- Low-grade Gliomasin Adults / Henry Marsh -- Neurosurgical Management of High-grade Gliomas / Robert C. Rostomily, Alexander M. Spence and Daniel L. Silbergeld -- Sellar and Parasellar Tumors / Richard J. Stacey and Michael P. Powell -- Meningiomas / James J. Evans, Joung H. Lee, John Suh and Mladen Golubic -- Intraventricular and Pineal Region Tumors / Sandeep Kunwar, G. Evren Keles and Mitchell S. Berger -- Cerebello-pontine Angle Tumors / Peter C. Whitfield and David G. Hardy -- Skull Base Tumors / Richard S. C. Kerr and Christopher A. Milford -- Tumors: Cerebral Metastases and Lymphoma / Sepideh Amin-Hanjani and Griffith R. Harsh -- Pediatric Neuro-oncology / Kevin L. Stevenson, J. Russell Geyer and Richard G. Ellenbogen -- Management of Spinal Tumors / Karl F. Kothbauer, George I. Jallo and Fred J. Epstein -- Management of Extradural Spinal Tumors / David A. Lundin, Charlie Kuntz and Christopher I. Shaffrey.
  • Lifestyle and Medical Approaches to Cancer Prevention / Peter Greenwald, p. 1-15 -- Application of Genetics to the Prevention of Colorectal Cancer / John Hopper, p. 17-33 -- Genetics and Prevention of Oesophageal Adenocarcinoma / Rebecca Fitzgerald, p. 35-46 -- Preclinical Models Relevant to Diet, Exercise, and Cancer Risk R. James Barnard and William Aronson, p. 47-62 -- Individualizing Interventions for Cancer Prevention / Michael Pollak, p. 63-70 -- Can Animal Models Help Us Select Specific Compounds for Cancer Prevention Trials? / Ernest Hawk, Asad Umar, Ronald Lubet, Levy Kopelovich and Jaye Viner, p. 71-88 -- Problems with Using Biomarkers as Surrogate End Points for Cancer: A Cautionary Tale / Arthur Schatzkin, p. 89-98 -- Can a Marker Be a Surrogate for Development of Cancer, and Would We Know It if It Exists? / William Armstrong, Thomas Taylor and Frank Meyskens, p. 99-112 -- How Should We Move the Field of Chemopreventive Agent Development Forward in a Productive Manner? / Frank Meyskens and Eva Szabo, p. 113-124 -- The Problems with Risk Selection; Scientific and Psychosocial Aspects / Anne-Renée Hartman, p. 125-144 -- Chemoprevention of Lung Cancer / Stéphane Vignot, Jean-Philippe Spano, Sylvie Lantuejoul, Fabrice André, Thierry Le Chevalier and Jean-Charles Soria, p. 145-165 -- Anti-nicotine Vaccination: Where Are We? / T. Cerny, p. 167-175 -- Primary Prevention of Colorectal Cancer: Lifestyle, Nutrition, Exercise / María Martínez, p. 177-211 -- Chemoprevention of Colorectal Cancer: Ready for Routine Use? / Nadir Arber and Bernard Levin, p. 213-230 -- Screening of Colorectal Cancer: Progress and Problems Sidney Winawer, p. 231-244 -- The Role of Endogenous Hormones in the Etiology and Prevention of Breast Cancer: The Epidemiological Evidence / Paola Muti, p. 245-256 -- Innovative Agents in Cancer Prevention / Margaret Manson, Peter Farmer, Andreas Gescher and William Steward, p. 257-275 -- The IARC Commitment to Cancer Prevention: The Example of Papillomavirus and Cervical Cancer / Silvia Franceschi, p. 277-297 -- Health Economics in the Genomic Age / Thomas Szucs, p. 299-313 -- Screening for Cancer: Are Resources Being Used Wisely? / Robert Kaplan, p. 315-334.
  • Tumor suppressor genes Springer Protocols
    v. 2 Springer Protocols
    v. 1 Pathways and isolation strategies -- v. 2 Regulation, function, and medicinal application.
  • During the last 20 years, it has become increasingly clear that the tumor micro-environment, the tumor stroma with its cellular end extracellular components, plays an crucial role in regulating tumor growth and progression. This book on 'Tumor-associated fibroblasts and their matrix' as part of the series on "Tumor-Microenvironment" is the first comprehensive discussion of these two main players of the tumor microenvironment. The best experts in this new area of tumor research and therapy review the role of these major components in the tumor stroma in the process of tumor developmen.
  • Tumors of the central nervous system v. 1-, 2011-, Springer
    Pt. 1. Astrocytomas : diagnosis and biomarkers -- pt. 2. Astrocytomas : therapy -- pt. 3. Astrocytomas : prognosis -- pt. 4. Hemangioblastoma -- pt. 5. Ganglioglioma -- pt. 6. Spinal Tumors (Part 1) -- pt. 7. Meningiomas and Schwannomas -- pt. 8. Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma.
  • v. 2, 2012 Springer
  • v. 4 Springer
  • The ninth volume in this essential series discusses key advances in our understanding of neoplasms in the human central nervous system. This publication deals with various aspects of nine separate types of brain tumors. With 70 contributors from 17 nations, this edition offers an unrivalled thoroughness and breadth of coverage that includes the very latest research results on the following tumor types: astrocytoma, lymphoma, supratentorial and glioneuronal tumors, gangliogliomas, neuroblastoma in adults, hemangioma, and ependymoma.The content introduces new technologies and their applications
  • Tumors of the chest 2006, Springer
  • Twenty years of G-CSF 2012, Springer
  • Two faces of evil 2011, Springer
    Homeostasis involves a delicate interplay between generative and degenerative processes to maintain a stable internal environment. In biological systems, equilibrium is established and controlled through a series of negative feedback mechanisms driven by a range of signal transduction processes. Failures in these complex communication pathways result in instability leading to disease. Cancer represents a state of imbalance caused by an excess of cell proliferation. In contrast, neurodegeneration is a consequence of excessive cell loss in the nervous system. Both of these disorders exhort profo
  • Urinary tract 2012, Springer
  • Urological cancers 2005, Springer
  • Urological oncology 2008, Springer
  • Uterine cancer 2009., Springer
    Essential epidemiology of cancer of the endometrium -- Endometrial cancer: screening, diagnosis, and surgical staging -- Imaging in the diagnosis and treatment of endometrial cancer -- Uterine cancer: pathology -- Molecular pathology and cytogenetics of endometrial carcinoma, carcinosarcoma, and uterine sarcomas -- Prognostic factors in uterine cancer -- Primary hormonal therapy of endometrial cancer -- Early-stage endometrial cancer: surgery -- Early-stage endometrial cancer: radiation -- Therapeutic modalities in early-stage uterine papillary serous carcinomas, carcinosarcomas, clear-cell and mixed histology carcinomas: building a case for combined chemotherapy and radiation -- Treatment of advanced and recurrent carcinoma: hormonal therapy -- Treatment of advanced and recurrent carcinoma: chemotherapy -- Treatment for advanced and recurrent carcinoma: combined modalities -- Management of uterine sarcomas -- Future directions: new targets.
  • Part 1. Pre-clinical development -- The Discovery and Characterisation of Tumour Endothelial Markers / Dario Neri and Roy Bicknell -- The Use of Animal Models in the Assessment of Tumour Vascular Disrupting Agents (VDAs) / R. Barbara Pedley and Gillian M. Tozer -- Combination Therapy with Chemotherapy and VDAs / Giulia Taraboletti, Katiuscia Bonezzi and Raffaella Giavazzi -- Lessons from Animal Imaging in Preclinical Models / Lesley D. McPhail and Simon P. Robinson -- Combining Antiangiogenic Drugs with Vascular Disrupting Agents Rationale and Mechanisms of Action / Yuval Shaked, Paul Nathan, Laura G. M. Daenen and Robert S. Kerbel -- Development of Vascular Disrupting Agents / Graeme J. Dougherty and David J. Chaplin -- Part 2. Imaging in the development of vascular disruptive agents -- MRI to Assess Vascular Disruptive Agents / Martin Zweifel and Anwar R. Padhani -- Contrast Ultrasound in Imaging Tumor Angiogenesis / Grzegorz Korpanty and Rolf A. Brekken -- Part 3. Clinical development -- The Clinical Development of Tubulin Binding Vascular Disrupting Agents / Martin Zweifel and Gordon Rustin -- ASA404 (DMXAA): New Concepts in Tumour Vascular Targeting Therapy / Bruce C. Baguley -- Vascular Disruptive Agents in Combination with Radiotherapy / Henry C. Mandeville and Peter J. Hoskin.
  • Cruciferous vegetables and biological activity of isothiocyanates and indoles -- Green leafy vegetables in cancer prevention -- The role of tomato lycopene in cancer prevention -- [Beta]-carotene and other carotenoids in cancer prevention -- The role of alliums and their sulfur and selenium constituents in cancer prevention -- Molecular mechanisms of chemoprevention with capsaicinoids for chili peppers -- Influence of dietary soy isoflavones genistein and daidzein on genotoxicity and mammary carcinogenicity in rats exposed to the model carcinogen 7, 12-dimethylbenz[a]anthracene (DMBA) -- The potential roles of seeds and seed bioactives on the prevention and treatment of breast and prostate cancer -- Nuts as part of a whole diet approach to cancer prevention -- Whole grains and their constituents in the prevention of colon cancer.
  • "This book presents a variety of vibrational spectroscopic techniques, focusing on Raman and Fourier transform infrared (FTIR) spectroscopy and their use in noninvasive optical tissue diagnosis. It covers the most recent research in this area to create a unique database of different chemical bands and their assignments of spectral bands. The text explores the spectroscopic investigation of different tissues and samples, including breast tissue, lung tissue, and brain tissue. Based on their years of experience with various applications, the authors provide definitions of peak frequencies as well as other aspects of spectroscopy that could be helpful to a wide range of scientists"--Provided by publisher.
  • Why we do CTC : screening for colorectal cancer / Richard M. Mendelson -- The performance of CTC / Didier Bielen -- Starting CT colonography in your department / Darra Murphy, Alan O'Hare, and Helen Fenlon -- The eligible patient : indications and contraindications / M. Raquel Oliva, Ayodale S. Odulate, and Koenraad J. Mortele -- Patient preparation for CT colonography / J. Yee -- The prerequisite : faecal tagging / Philippe Lefere and Stefaan Gryspeerdt -- How to get the colon distended? / David Burling, Stuart Taylor, and Steve Halligan -- Right parameters / Andrea Laghi -- How to interpret CTC data : evaluation of the different lesion morphologies / Beth G. McFarland -- How to avoid pitfalls in imaging : causes and solutions to overcome false-negatives and false-positives / Stefaan Gryspeerdt and Philippe Lefere -- 3D imaging : invaluable for the correct diagnosis? / Ayso H. De Vries and Jaap Stoker -- The challenge : detection of early-stage superficial colorectal lesions -- Gen Iinuma ... [et al.] -- Extracolonic findings / Francesca Turini, Francesca Cerri, and Emanuele Neri -- The future : computer-aided detection / H. Yoshida -- Quality and consistency in reporting CT colonography / Abraham H. Dachman, Piotr R. Obara, and Michael E. Zalis -- Virtual colonoscopy : beyond polyp detection? / T. Mang ... [et al.] -- Pictorial overview of normal anatomy, mimics of disease, and neoplasia using CT colonography / J.G. Fletcher, Fargol Booya, and Luis S. Guimaraes.
  • Vitamin D and cancer 2011, Springer
  • Negotiating personal and political settlements with breast cancer: women finding their own ways to live with human contingency / Rosemarie Tong -- Personalizing the political: negotiating the feminist, medical, scientific and commercial discourses surrounding breast cancer / Susan Sherwin -- Power, gender, and pizzazz: the early years of breast cancer activism / Barron Lerner -- Breast cancer: dueling discourses and the persistence of an outmoded paradigm / Gwynne Gertz -- Doing things with ideas and affects in the illness narratives of Susan Sontag and Eve Kosofsky Sedgwick / Lisa Diedrich -- The breast cancer diaries / Anita Ho -- Breast cancer: the maternal body reflected in a three-way mirror / Debra Gold -- Learn to love what's left: poems on breast cancer / Leatha Kendrick -- Death and the other: rethinking authenticity / Gail Weiss -- Breast cancer research: a political cause and paradigm for scientific inquiry / John S. Kovach -- Clinical trials for breast cancer and informed consent: how women helped make research a cooperative venture / Loretta M. Kopelman -- The role of psychosocial research in understanding and improving the experience of breast cancer and breast cancer risk / Anne Moyer and Marci Lobel -- Teaching about breast cancer and "common health" / Helen Rodnite Lemay -- Theoretical considerations on "reading" the breast / Tanfer Emin-Tunc -- Recent developments in breast cancer research / Sofya Maslyanskaya.
  • War on cancer 2005, Springer
  • Astrocytic Tumours -- Oligodendroglial Tumours -- Ependymal Tumours -- Choroid Plexus Tumours -- Other Neuroepithelial Tumours -- Neuronal and Mixed Neuronal- Glial Tumours -- Tumours of the Pineal Region -- Embryonal Tumours -- Tumours of the Cranial and Paraspinal Nerves -- Meningeal Tumours -- Tumours of the Haematopoietic System -- Germ Cell Tumours -- Familial Tumour Syndromes involving the Nervous System -- Tumours of the Sellar Region --Metastatic Tumours of the CNS.
  • Epidemiology / David Neary -- Economic burden / Richard J. Butler, William G. Johnson, and Timothy Gubler -- Employers' and survivors' perspectives / Ziv Amir, David R. Strauser, and Fong Chan -- Work disability : it is not just the "lesion" / Patrick Loisel -- The meaning of work / Guy Maytal and John Peteet -- Fatigue, pain, and physical function / Mary E. Sesto and Maureen J. Simmonds -- Cognitive limitations / Tracy Veramonti and Christina Meyers -- Young survivors of childhood cancer / Angela de Boer, Jos Verbeek, and Frank van Dijk -- Primary and occupational health care providers / Jos Verbeek, Angela de Boer, and Taina Taskila -- Rehabilitation / Michael J.L. Sullivan ... [et al.] -- Workplace accomodations / Fong Chan ... [et al.] -- Individuals with cancer in the workforce and their federal rights / Peter Blanck ... [et al.] -- International efforts : perspectives, policies, and programs / Patricia Findley and Catherine P. Wilson -- Future research, practice, and policy -- Michael Feuerstein.
  • From DNA replication to genome instability in schizosaccharomyces pombe: pathways to cancer /Julie M. Bailis and Susan L. Forsburg --Dissecting layers of mitotic regulation essential for maintaining genomic stability /Jeffiner S. Searle and Yolanda Sanchez --Yeast as a tool in cancer research: nuclear trafficking /Anita H. Corbett and Adam C. Berger --Studies of protein farnesylation in yeast /Nitika Thaper and Fuyuhiko Tamanoi --From bread to bedside: what budding yeast has taught us about the immortalization of cancer cells /Soma S.R. Banik and Christopher M. Counter --Hsp90 co-chaperones in saccharomyces cerevisiae /Marija Tesiccc and Richard F. Gaber --Yeast as a model system for studying cell cycle checkpoints /Carmela Palermo and Nancy C. Walworth --Metabolism and function of sphingolipids in saccharomyces cerevisiae: relevance to cancer research /L. Ashley Cowart, Yusuf A. Hannun, and Lina M. Obeid --Exploring and restoring the p53 pathway using the p53 dissociator assay in yeast /Rainer K. Brachmann --Functional analysis of the Human p53 tumor suppressor and its mutants using yeast /Alberto Inga, Francesca Storici and Michael A. Resnick --ABC transporters in yeast - drug resistance and stress response in a nutshell /Karl Kuchler and Christoph Schüller --The FHCRC/NCI yeast anticancer drug screen /Susan L. Holbeck and Julian Simon --Yeast as a model to study the immunosuppressive and chemotherapeutic drug rapamycin /John R. Rohde, Sara A. Zurita-Martinez, and Maria E. Cardenas --Use of yeast as a model of system for identifying and studying anti-cancer drugs /Jun O. Liu and Julian A. Simon --Genetic analysis of cisplatin resistance in yeast and mammals /Seiko Ishida and Ira Herskowitz --Using yeast tools to dissect the action of anti-cancer drugs: mechanisms of enzyme inhibition and cell killing: agents targeting DNA topoisomerases /Anna Rogojina, ... [et al].
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Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides one-click access to important clinical resources; includes evidence-based diagnosis and treatment guidelines, Books, EBM articles, Ovid MEDLINE, Drug facts and comparisons, Drug interaction facts, guidelines from National Guideline Clearinghouse, patient handouts (English and Spanish), and local content.MD consult provides access to textbooks, electronic journals, practice guidelines, drug information, and patient education handouts.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.
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