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  • New Techniques for Thoracic Outlet Syndromes presents in a comprehensive format an up-to-date, state of the art reference that physicians can use in consultation to properly treat patients using the resources that modern medicine offers. This book offers the newer surgical approaches that have been developed during the past 30 years. Some of these techniques are modification of operations that were proposed previously but were not fully affective and left many patients suffering with permanent disability. This textbook is a compendium of the proper management of these patients that cannot be found in isolated reports of literature. The neurogenic-arterial thoracic outlet syndrome section covers how to diagnosis the illness using the proper tests, therefore eliminating the use of expensive, uncomfortable and inconvenient tests. The text is organized in three basic sections that cover all the aspects of the thoracic outlet syndromes. The first section addresses the neurogenic-arterial type, with the pertinent subsections: symptoms, diagnosis. A list of the useful tests is provided to make a correct diagnosis of this syndrome. This is followed by the sections on treatment, using the surgical approaches with historical aspects and evolution of the operations proposed. The second section involves the venous thoracic outlet syndrome divided into the corresponding subsections comprising: symptoms and physical findings, etiology, diagnosis. This section also includes a list of the usual tests to make the proper diagnosis. The last section of this text is dedicated to the presence of cervical ribs and their classification of the different types that occur, and also the proper surgical treatment when fusion of the upper ribs is present. New Techniques for Thoracic Outlet Syndromes offers the current, acceptable and most effective methods to handle thoracic outlet syndromes. It will be of great value to thoracic surgeons, vascular surgeons, interventional radiologists as well as fellows and residents in training for cardiothoracic and vascular surgery.
  • v. 221 ScienceDirect
    New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.
  • "This edition has several new features, reflective of the changes that have occurred in our field over the last 5 years since the fifth edition. More and more, the field of digital recording has expanded; however, in order to understand some of the shortcomings and pitfalls of digital EEG, people need to still address the issues of basic analog recording principles. With an increased use of digital recording, laboratories have collected new and different "technical artifacts." We present here an attempt to start a database for such artifacts in a hopes that future editions will continue to expand upon this and offer a fairly complete library for beginning individuals interested in our field. As noted in the fifth edition, epilepsy monitoring units (EMU's) have continued to mushroom. Similar growth has occurred in the use of EEG monitoring in newborn, cardiac, trauma, and post-operative intensive care units. With the significant advances in wireless communication and easy access to the Internet, such recordings can also be viewed and transmitted locally virtually instantaneously and can allow for well-trained clinical neurophysiologists to see and opine about patients' conditions on a very time-relevant basis. Hopefully, as future generations may show, this ability will significantly influence our patients' outcomes. Similarly, the field of intraoperative clinical neurophysiology for spinal cord function, cranial nerve function, and cranial vascular therapies has continued to evolve along with the wireless and iInternet communications. This has allowed for close monitoring of neurologic function during critical periods of operations, again with a time course that allows for corrective actions to be taken on a meaningful time frame"--Provided by publisher.
  • Gross anatomy of the brain -- Neurons and associated cells -- Basic neurophysiology -- Blood circulation and imaging -- Meninges, ventricles, and cerebrospinal fluid -- Development and growth of the nervous system -- The spinal cord -- Reflexes and muscle tone -- Pain and temperature -- Discriminative general senses, crude touch, and proprioception -- Motoneutrons and motor pathways -- Lesions of the spinal nerves and spinal cord -- Brainstem : medulla, pons, and midbrain -- Cranial nerves and chemical senses -- Neurotransmitters as the chemical messengers of certain circuits and pathways -- Auditory and vestibular systems -- Lesions of the brainstem -- Cerebellum -- The visual system -- Autonomic nervous system -- Hypothalamus -- The reticular formation and the limbic system -- Thalamus -- Basal ganglia and extrapyramidal system -- Cerebral cortex.
  • In our industrialized world, we are surrounded by occupational, recreational, and environmental noise. Very loud noise damages the inner-ear receptors and results in hearing loss, subsequent problems with communication in the presence of background noise, and, potentially, social isolation. There is much less public knowledge about the noise exposure that produces only temporary hearing loss but that in the long term results in hearing problems due to the damage of high-threshold auditory nerve fibers. Early exposures of this kind, such as in neonatal intensive care units, manifest themselves at a later age, sometimes as hearing loss but more often as an auditory processing disorder. There is even less awareness about changes in the auditory brain caused by repetitive daily exposure to the same type of low-level occupational or musical sound. This low-level, but continuous, environmental noise exposure is well known to affect speech understanding, produce non-auditory problems ranging from annoyance and depression to hypertension, and to cause cognitive difficulties. Additionally, internal noise, such as tinnitus, has effects on the brain similar to low-level external noise. Noise and the Brain discusses and provides a synthesis of the underlying brain mechanisms as well as potential ways to prvent or alleviate these aberrant brain changes caused by noise exposure. Authored by one of the preeminent leaders in the field of hearing research. Emphasizes direct and indirect changes in brain function as a result of noise exposure. Provides a comprehensive and evidence-based approach. Addresses both developmental and adult plasticityIncludes coverage of epidemiology, etiology, and genetics of hearing problems; effects of non-damaging sound on both the developing and adult brain; non-auditory effects of noise; noise and the aging brain; and more.
  • Diseases of the respiratory system often cause multisystem dysfunction and morbidity. Respiratory diseases not transmissible by a direct contact are rarer than those of inflammatory or infectious background. Such noncommunicable diseases, often entailing genetic and immune aspects, are areas of limited understanding; sarcoidosis being a case in point. This book tackles the issues relevant to such diseases. The research on novel cytokine markers, which may help in the diagnosis and management of sarcoidosis, is described. Modern approaches to the management of pneumothorax, a frequent accompaniment of lung diseases or chest wall trauma are dealt with as well. There are also chapters that underscore the immuno-inflammatory mechanisms of disorders seemingly unrelated to respiration, such as obesity or aplastic anemia, which may appreciably affect the control of the respiratory system and thus its vulnerability to diseases. The book will be of interest to clinicians and medical researchers.
  • Overview of cerebrovascular disease -- Overview of various noninvasive cerebrovascular techniques -- Duplex scanning of the carotid arteries -- The role of color duplex scanning in diagnosing diseases of the aortic arch branches and carotid arteries -- Vertebral artery ultrasonography -- Transcranial Doppler sonography -- Ultrasonic characterization of carotid plaques -- Carotid plaque echolucency measured by grayscale median identifies patients at increased risk of stroke during carotid stenting: the imaging in carotid antioplasty and risk of stroke study -- Duplex ultrasound in the diagnosis of temporal arteritis -- Duplex ultrasound velocity criteria for carotid stenting patients -- Use of transcranial Doppler in monitoring patients during carotid artery stenting -- Use of an angle-independent Doppler system for intraoperative carotid endarterectomy surveillance -- Clinical implications of the vascular laboratory in the diagnosis of cerebrovascular insufficiency.
  • Novel approaches in migraine treatment / Hans-Christoph Diener -- Potential treatment targets and the experience with triptans / Saurabh Gupta -- Calcitonin gene-related peptide receptor antagonists / Thomas P. Bravo, Bert B. Vargas & Rashmi B. Halker -- Lasmiditan / Alison J. Pilgrim, Uwe Reuter & Hans-Christoph Diener -- Microglial modulation in migraine / Jason D. Rosenberg, B. Lee Peterlin & Alan M. Rapoport -- Transcranial magnetic stimulation for migraine treatment / Stefan Evers -- Patent foramen ovale closure / Markus Schwerzmann, Hans-Christoph Diener & Bernhard Meier -- Biofeedback enhances the migraine threshold / Roger K. Cady & Kathleen Farmer -- Botulinum toxin for migraine treatment / Oliver Summ, Stefan Evers & Ingo W. Husstedt -- Sphenopalatine ganglion stimulation in primary headaches / Shaheen E. Lakhan, Stewart J. Tepper & Mihaela Avramut -- Nutraceuticals in migraine treatment / Saras Menon & Lyn R. Griffiths -- Index.
  • Novel insights into the pathophysiology and treatment of fibromyalgia / Bente Danneskiold-Samsøe & Else Marie Bartels -- The history of fibromyalgia / Bente Danneskiold-Samsøe & Else Marie Bartels -- Pain in fibromyalgia / Kirstine Amris -- Pain assessment in fibromyalgia / Else Marie Bartels & Bente Danneskiold-Samsøe -- Fatigue and fibromyalgia / Philip Mease -- Genetic influence on fibromyalgia / Laia Rodriguez-Revenga, Elisa Docampo, Antonio Collado & Montserrat Mila -- Biomarkers in fibromyalgia / Nurcan Üçeyler & Claudia Sommer -- Assessment of activities of daily living in fibromyalgia / Eva E. Wæhrens -- Assessment of muscle strength and muscle function in fibromyalgia / Kaisa Mannerkorpi & Petri Salo -- Clinical assessment of fibromyalgia / Bente Danneskiold-Samsøe & Else Marie Bartels -- Treatment options for fibromyalgia / David A. Williams & Daniel J. Clauw -- Index.
  • Object recognition. Occlusion awaits disclosure / Gijs Plomp, Cees van Leeuwen -- Functional MRI evidence for neural plasticity at early stages of visual processing in humans / Sophie Schwartz -- Pattern recognition in direct and indirect view / Hans Strasburger, Ingo Rentschler -- Part based strategies for visual categorisation and object recognition / Martin Juttner -- Recent psychophysical and neural research in shape recognition / Irving Biederman -- Object recognition in humans and machines / ChristianWallraven, Heinrich H. Bulthoff -- Prior knowledge and learning in 3D object recognition / Markus Gschwind, Hans Brettel, Ingo Rentschler -- Neural representation of faces in human visual cortex : the roles of attention, emotion, and viewpoint / Patrik Vuilleumier -- Attention. Object recognition : attention and dual routes / Volker Thoma, Jules Davidoff -- Interactions between shape perception and egocentric localization / Hiroyuki Sogo, Naoyuki Osaka -- Feature binding in visual working memory / Jun Saiki -- Biased competition and cooperation : a mechanism of mammalian visual recognition? / Gustavo Deco, Martin Stetter, Miruna Szabo -- Action. Influence of visual motion on object localisation in perception and action / Hiroshi Ashida -- Neural substrates of action imitation studied by fMRI / Shigeki Tanaka -- Two types of anticipatory timing mechanisms in synchronization tapping / Yoshihiro Miyake, Yohei Onishi, Ernst Poppel.
  • This book provides a comprehensive account of the pathogenesis, clinical features, and management of ocular vascular occlusive disorders, with the focus very much on the scientific evidence. This offers a sound basis for addressing the many controversies that surround these disorders, which collectively constitute the most common cause of visual impairment or blindness. The book is divided into two sections, the first of which addresses the basic science and encompasses vascular anatomy, blood supply and flow, and retinal tolerance time to acute ischemia. The second, clinical, section covers the presentation, clinical features, diagnosis, and treatment of the full range of vascular occlusive disorders of the retina, the choroid, the anterior segment of the eye, ophthalmic manifestations of carotid artery disease and the optic nerve. ℗ℓ In writing Ocular Vascular Occlusive Disorders, the author has drawn upon more than 55 years of experience in basic and clinical research. The book will be an invaluable source of information for general ophthalmologists, and particularly for retina specialists, neuro-ophthalmologists, and researchers. It is hoped that it will go far in rectifying the lack of in-depth scientific understanding that is the source of many misapprehensions and debates.
  • This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume explores interdisciplinary research on invertebrate and vertebrate models of odor memory and perception, as well as human odor memory and perception. This book brings together a collection of authors that cut across model systems, techniques, levels of analysis and questions to highlight important and exciting advances in the area of olfactory memory and perception.
  • Omega-6/omega-3 essential fatty acids : biological effects / Simopoulos, A.P. -- Depression, suicide, and deficiencies of omega-3 essential fatty acids in modern diets / Hibbeln, J.R. -- Serial structural magnetic resonance imaging analysis and proton and 31-phosphorus magnetic resonance spectroscopy to the investigation of cerebral fatty acids in major depressive disorder, Huntington's disease (chorea), and myalgic encephalomyelitis (chronic fatigue syndrome), and in forensic schizophrenic patients / Puri, B.K.; Tsaluchidu, S.; Treasaden, I.H. -- Omega-3 fatty acid docosahexaenoic acid is the precursor of neuroprotectin D1 in the nervous system / Niemoller, T.D.; Stark, D.T.; Bazan, N.G. -- Docosahexaenoic acid and amyloid-[beta] peptide signaling in Alzheimer's disease / Lukiw, W.J. -- Administration of docosahexaenoic acid, uridine, and choline increases levels of synaptic membranes and dendritic spines in rodent brain / Wurtman, R.J. ... [et al.] -- An assessment of dietary docosahexaenoic acid requirements for brain accretion and turnover during early childhood / Hadley, K.B. ... [et al.] -- Variation in lipid-associated genes as they relate to risk of advanced age-related macular degeneration / SanGiovanni, J.P., Mehta, S., Mehta, S.
  • Operative neuromodulation v. 1-2, 2007.
    v. 2, 2007 Springer
    v. 1. Functional neuroprosthetic surgery -- v. 2. Neural networks surgery.
  • Optic Nerve Disorders: Diagnosis and Management, Second Edition, is a thoroughly revised and updated reference, including new information on diagnostic techniques such as genetic testing for hereditary optic neuropathies, new data on toxic/drug-related optic neuropathies, and recent data from clinical trial studies. Additional novel therapies, including stem cell therapies, the use of nanotechnology, and gene therapies are featured highlights, as is spectral domain optical coherence tomography (OCT) for imaging of the optic nerve. The way in which OCT is used in differentiating optic nerve disorders from other retinal disorders, and how OCT is used in monitoring the course of the disease, is also discussed. This practical reference focuses on common optic nerve disorders. It addresses diagnosis, pathophysiology, management, and prognosis, and is written in a clear, concise style for quick, easy reference in the clinic. With additional color photographs to better illustrate the material, the second edition will prove to be the go-to reference for ophthalmologists, neurologists, and neurosurgeons working with optic nerve disorders.
  • Optogenetics is a fast-growing field concerning the invention, and use, of molecules that are genetically expressed in cells, and then either report on cellular physiology in optical form, or enable control of specific pathways in cells when actuated by light. This book reviews the current state, as well as the underlying principles and future directions, of a diversity of optogenetic tools of importance for observing and controlling cellular signaling and physiology. These tools are already revolutionizing neuroscience, and are starting to have impact on fields ranging from metabolism to
  • This issue of Progress in Brain Research reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist.
  • 1. The Neurobiology of Orofacial Pain -- 2. Oral Health Related Quality of Life and Facial Pain -- 3. Classification and Epidemiology of Orofacial Pain -- 4. Nociceptive Chemical Mediators In Oral Inflammation -- 5. Dental Sleep Medicine and the Use of Oral Devices -- 6. Local Anesthesia in the Orofacial Region -- 7. Analgesics and adjuvants for the management of orofacial pain across age groups -- 8. Cognitive-Behavioral Therapy in Pain Management -- 9. Management of Oral Ulcers and Burning Mouth Syndrome -- 10. Hypnosis and Biofeedback for Orofacial Pain Management -- 11. Headaches, Migraine and Cluster Headache -- 12. Management of Orofacial Neuropathic Pain -- 13. Preemptive Analgesia and Multimodal Pain Management for Temporomandibular Total Joint Replacement Surgery.
  • Print Material
    "Osborn's Brain: Imaging, Pathology, and Anatomy is the much-pleaded-for successor to Anne G. Osborn's 1993 award winning book Diagnostic Neuroradiology (a.k.a. "The Red Book"), which became one of the all-time bestselling neuroradiology texts. In this highly anticipated 1,200-page volume, Anne Osborn applies her special touch to make complex topics visually appealing and easy to understand. It wraps the "must know" aspects of brain imaging together with spectacular pathology examples, relevant anatomy, and the most up-to-date modalities and techniques in brain imaging"--Provided by publisher.
  • Chapter 1: The Role of Free Radicals in the Nervous System -- Chapter 2: Why Is the Nervous System Vulnerable to Oxidative Stress? -- Chapter 3: Perinatal Hypoxic-Ischemic Neural Injury and Free Radical Injury: A Fine Balance -- Chapter 4: Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy -- Chapter 5: Oxidative Stress in Multiple Sclerosis Pathology and Therapeutic Potential of Nrf2 Activation -- Chapter 6: Free Radicals in Central Nervous System Inflammation.
  • Section I. Palliative management -- Introduction to palliation -- Characteristics of palliation -- Nodal points in decision-making -- Common deficiencies in palliative management -- Common themes in palliation practice -- Section II. Major discomforts in advanced neurological illness -- Fatigue -- Problems with muscles and movement -- Bulbar symptoms -- Respiratory symptoms -- Gastrointestinal symptoms -- Urological symptoms -- Pain -- Cognitive, behavioural and psychological symptoms -- Miscellaneous symptoms -- Section III. Major neurological conditions requiring palliation -- Cerebrovascular diseases : stroke -- Demyelinating diseases -- Parkinson's disease and related disorders -- Dementia -- Amyotrophic lateral sclerosis (motor neurone disease) -- Incurable infections of the nervous system -- Muscular dystrophy -- Neuropathies -- Huntington's disease -- Cerebral neoplasms -- Sequelae of traumatic brain injury -- Section IV. Ethical Issues -- Consent and decision-making -- Advance directives -- Proxy decision-making -- Ethical issues in states of disordered consciousness -- Terminal sedation -- Euthanasia -- Section V. Appendices.
  • "The first authoritative review on the parasomnias - disorders that cause abnormal behavior during sleep - this book contains many topics never before covered in detail. The behaviors associated with parasomnias may lead to injury of the patient or bed-partner, and may have forensic implications. These phenomena are common but often unrecognized, misdiagnosed, or ignored in clinical practice. With increasing awareness of abnormal behaviors in sleep, the book fulfils the need for in-depth descriptions of clinical and research aspects of these disorders, including differential diagnosis, pathophysiology, morbidity, and functional consequences of each condition, where known. Appropriate behavioral and pharmacological treatments are addressed in detail. There are authoritative sections on disorders of arousal, parasomnias usually associated with REM sleep, sleep-related movement disorders and other variants, and therapy of parasomnias. Sleep specialists, neurologists, psychiatrists, psychologists and other healthcare professionals with an interest in sleep disorders will find this book essential reading"--Provided by publisher.
  • Part I. Overview -- Introduction -- Pathophysiology of parasomnias -- Classification of parasomnias -- Diagnosing parasomnias -- Part II. Clinical characteristics of arousal disorders -- Sleepwalking and its variants in adults -- Sleepwalking in children and adolescents -- Sleep terrors and confusional arousals in adults -- Sleep terrors and confusional arousals in children and adolescents -- Part III. Clinical characteristics of sleep-wake transition disorders -- Sleep starts and sleep talking -- Part IV. Clinical characteristics of parasomnias associated with REM sleep -- Physiology and content of dreams -- Nightmare disorders in adults -- Nightmare disorders in children -- Recurrent isolated sleep paralysis (RISP) -- Sleep-related hallucinations -- REM behavior disorder in adults -- REM behavior disorder in children -- Part V. Other parasomnias -- Nocturnal paroxysmal dystonia -- Sleep related dissociative disorders -- Sleep bruxism -- Nocturnal enuresis -- Sleep-related eating disorders: a separate entity or part of the NES clinical spectrum? -- Parasomnia overlap disorder -- Part VI. Neurological, psychiatric and medical disorders presenting as parasomnias -- Neurological conditions associated with parasomnias -- Psychiatric disorders presenting with parasomnias -- Medical disorders presenting with parasomnias -- Parasomnias caused by other conditions -- Part VIII. Interventions for parasomnias -- Treatment of parasomnias -- Use of alternative medicines in parasomnias for adults and children -- Part VIII. Medioclegal aspects -- Sexxomnia: a medicolegal case-based approach in analyzing potential sleep-related abnormal sexual behaviors -- Forensic aspects of the parasomnias.
  • Top experts from all over the world have been brought together by the editors, to give a world of expertise on this important subject, with a strong emphasis on therapy and management.
  • Parkinson's disease : diagnosis, motor symptoms and non-motor features / Joseph Jankovic -- Redefining Parkinson's disease / Charles H. Adler & Matthew B. Stern -- Motor features of Parkinson's disease / Ainhi D. Ha, Samuel D. Kim & Victor S.C. Fung -- Olfaction, pain and other sensory abnormalities in Parkinson's disease / Antoniya Todorova & Kallol Ray Chaudhuri -- Cognitive and behavioral abnormalities in Parkinson's disease / Laura Marsh -- Autonomic dysfunction in Parkinson disease / Lucy Norcliffe-Kaufmann & Horacio Kaufmann -- Biomarkers for Parkinson's disease / Andrew Siderowf -- Animal models of Parkinson's disease / Weidong Le & Joseph Jankovic -- Differentiating Parkinson's disease from other Parkinsonian disorders / Joseph Jankovic -- Multiple choice questions : answers.
  • Parkinson's disease : medical and surgical treatment / Joseph Jankovic -- Prevention of Parkinson's disease : preparing for the future / Connie Marras -- Initial and disease-modifying strategies in Parkinson's disease / Lawrence W. Elmer & Robert A. Hauser -- Prevention and management of levodopa-related motor complications / Cara A. Pecina & Alberto J. Espay -- Management of non-motor symptoms of Parkinson's disease / Mark Stacy -- Management of cognitive and behavioral aspects of Parkinson's disease / Joseph H. Friedman -- Surgical therapy for Parkinson's disease / Nawaz Hack & Michael S. Okun -- Experimental therapeutics for motor symptoms of Parkinson's disease / Susan H. Fox & Lorraine V. Kalia -- Parkinson's disease treatment pipelines / Joseph Jankovic -- Multiple choice questions : answers.
  • Part I: Overview -- Part II: Epidemiology -- Part III: Genetics -- Part IV: Clinical Features of Parkinson's Disease -- Part V: Pathophysiology of Parkinson's Disease -- Part VI: Theories of Pathogenesis -- Part VII: Diagnosis of Parkinson's Disease.
  • 1 Anatomy of headache -- 2 Animal models of migraine -- 3 Animal models of other primary headaches -- 4 Genetics of headache -- 5 Human models of primary headaches -- 6 Imaging of migraine -- 7 Imaging of other primary headaches -- 8 Neurophysiology of migraine -- 9 Neurophysiology of other primary headaches -- 10 Biochemistry of primary headaches -- 11 Pathophysiology of migraine: current status and future directions -- 12 Pathophysiology of TTH: current status and future directions -- 13 Pathophysiology of cluster headache: current status and future directions -- 14 Pathophysiology of MOH: current status and future directions.
  • Section 1. Induction and patterning of the CNS and PNS -- section 2. Generation of neuronal diversity -- section 3. Development of glia, blood vessels, choroid plexus, immune cells in the nervous system.
  • Between the growing numbers of children and adolescents playing sports and the increased attention to head injuries by the larger sports community and the general public, pediatric concussions are emerging as a major concern. And as practitioners are seeing more young clients with head injuries, questions arise about age-appropriate assessment, diagnosis, treatment, and return to activity. Pediatric and Adolescent Concussion: Diagnosis, Management, and Outcomes offers evidence-based guidelines where few previously existed. This comprehensive volume clearly explains the effects of traumatic injury on the developing brain in sports- and non-sports-related contexts, and establishes a framework for immediate and long-term management, especially the crucial first 24 hours. Chapters provide a basic grounding in its subject with a history of concussion as a medical entity and a review of definitional and classification issues, take the reader through the steps of a neuropsychological evaluation, pinpoint post-injury issues, and offer strategies for the prevention of further or future injury. Pediatric and Adolescent Concussion: Diagnosis, Management, and Outcomes serves as both educational resource and practical framework for a wide array of professionals, including neuropsychologists, sports medicine physicians, child psychologists and psychiatrists, pediatric and family physicians, athletic trainers, social workers, and educators.
  • Section I. The Respiratory System in Critical Illness and Injury -- Section II. The Cardiovascular System in Critical Illness and Injury -- Section III. The Central Nervous System in Critical Illness and Injury -- Section IV. The Gastrointestinal System in Critical Illness and Injury -- Section V. The Endocrine System in Critical Illness and Injury -- Section VI. The Renal System in Critical Illness and Injury -- Section VII. The Hematologic System in Critical Illness and Injury -- Section VIII. Oncologic Disorders in the PICU -- Section IX. The Immune System in Critical Illness and Injury.
  • The contributions in this volume cover recent advances and changing concepts on diagnosis and treatment of resistant epilepsy in children. Topics treated are new insights on mechanisms of epileptogenesis in developing brain, multimodality imaging in pediatric intractable epilepsy, pediatric intractable epilepsy syndromes, pediatric temporal lobe epilepsy surgery, critical review of palliative surgical techniques for intractable epilepsy, treatment modalities for intractable epilepsy in hypothalamic hemartomas, contemporary management of epilepsy in tuberous sclerosis.
  • "Neurogastroenterology is devoted to studying "the interface of all aspects of the digestive system with the different branches of the nervous system." Over the past 15 years, advances in this field have greatly improved our understanding in primary functional and motility disorders in children. Neurogastroenterology has also begun to revolutionize our vision of "organic" diseases like inflammatory bowel disease, obesity, and diabetes, as well as microbial-host interactions. Major advances have also been achieved during these years in the knowledge of mechanisms of development of the enteric nervous system at the molecular level, allowing a better understanding of diseases related to developmental anomalies and opening perspectives to new treatments with stem cells. * Pediatric Neurogastroenterology: Gastrointestinal Motility and Functional Disorders in Children is dedicated to reporting the most accurate and recent knowledge in the field. Written by the world-renown experts, the book covers the field by providing a comprehensive and up-to-date review and practical guide to pediatric gastrointestinal motility and functional disorders for pediatricians, pediatric gastroenterologists, adult gastroenterologists and all professionals involved in the treatment of children with such disorders"--Publisher's description.
  • Techniques and methods in pediatric neuroimaging / Christopher P. Hess and A. James Barkovich -- Normal development of the neonatal and infant brain, skull and, spine / A. James Barkovich and Pratik Mukherjee -- Metabolic, toxic, and inflammatory brain disorders / A. James Barkovich and Zoltan Patay -- Brain and spine injuries in infancy and childhood / Erin Simon Schwartz and Jim Barkovich -- Congenital malformations of the brain and skull / A. James Barkovich and Charles A. Raybaud -- The phakomatoses / Gilbert Vezina and A. James Barkovich -- Intracranial, orbital, and neck masses of childhood / Charles Raybaud and A. James Barkovich -- Hydrocephalus / A. Raybaud and A. James Barkovich -- Congenital anomalies of the spine / Erin Simon Schwartz and A. James Barkovich -- Neoplasms of the spine / A. James Barkovich -- Infections of the developing and mature nervous system / Gary Hedlund and A. James Barkovich -- Anomalies of cerebral vasculature: diagnostic and endovascular considerations / Philip M. Meyers, Van V. Halbach, and A. James Barkovich.
  • Suggestions for history and physical examination -- Headache -- School problems and attention-deficit hyperactivity disorder -- Abnormal movements -- Behavioral and sleep problems -- Seizures, epilepsy, and related disorders -- Dizziness, fainting, and loss of balance -- Delay or regression of motor development associated with low muscle tone -- Autism and language disorders -- Cerebral palsy (static encephalopathy) and related problems -- Abnormalities of cranial size and shape, hydrocephalus, and spinal dysraphism -- Common neurological complications of trauma -- Stroke, acute paraparesis, and other serious disorders of acute and subacute onset -- Other important neurological syndromes.
  • pt. II ScienceDirect
    Pt. III ScienceDirect
    The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology - not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed - brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed. *A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. *International list of contributors including the leading workers in the field. *Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.
  • v. 1. Brain -- v. 2. Head and neck, spine.
  • Bridging the gap between the pediatric specialist unaccustomed to handling neurovascular pathologies and the neurovascular specialist unaccustomed to treating pediatric patients, this text covers the cutting-edge, multi-modal techniques for managing pediatric neurovascular disease, disorders, and malformations. It contains full descriptions and perspectives on the most advanced surgical, endovascular, and medical treatments for cerebral aneurysms, arteriovenous fistulas, arteriovenous malformations, Galen's vein malformations, moyamoya disease, spinal vascular malformations, pediatric stroke, and more.
  • The perception-action cycle is the circular flow of information that takes place between the organism and its environment in the course of a sensory-guided sequence of behaviour towards a goal. Each action causes changes in the environment that are analyzed bottom-up through the perceptual hierarchy and lead to the processing of further action, top-down through the executive hierarchy, toward motor effectors. These actions cause new changes that are analyzed and lead to new action, and so the cycle continues. The Perception-action cycle: Models, architectures and hardware book provides focused.
  • Peripheral and cerebrovascular disease / Vijay Nambi and Deepak L. Bhatt -- Lower extremity intervention / Samir K. Shah and Daniel G. Clair -- Critical limb ischemia / Raghotham Patlola and Craig Walker -- Renal and mesenteric intervention / Ramy A. Badawi and Christopher J. White -- Subclavian and upper extremity interventions / Khung Keong Yeo and John R. Laird -- Carotid and vertebral intervention / Douglas E. Drachman, Nicholas J. Ruggiero II and Kenneth Rosenfield -- Intracranial intervention / Muhammad Shazam Hussain and Rishi Gupta -- Abdominal and thoracic aortic aneurysms / Aravinda Nanjundappa ... [et al.] -- Venous intervention / Andrew B. McCann and Robert M. Schainfeld.
  • The new edition of this practical multimedia resource shows you exactly how to perform successfully a full range of peripheral nerve block techniques. Over four hundred illustrations, the majority of which are in colour, the relevant surface anatomy, the internal anatomy, the ultrasonographic anatomy to vividly depict correct needle placement in real patients.
  • Peripheral nerve disorders 2013
    "Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities"--Publisher's description.
  • The Peripheral Nervous System: Anatomy and Function -- Reactions to Injury -- Regeneration and Recovery of Function -- Clinical Aspects of Nerve Injury -- Operating on Peripheral Nerves.
  • History of peripheral nerve stimulation / Slavin, K.V. -- Central Mechanisms of Peripheral nerve stimulation in headache disorders / Bartsch, T., Goadsby, P.J. -- Peripheral nerve stimulation for chronic neurogenic Pain / Al-Jehani, H., Jacques, L. -- Percutaneous peripheral nerve stimulation / Al, K.M., Abramova, M.V., Richter, E.O. -- Peripheral nerve stimulation for the treatment of truncal pain / Cairns, K.D., McRoberts W.P., Deer, T. -- Peripheral subcutaneous stimulation for intractable abdominal pain / Barolat, G. -- Subcutaneous occipital region stimulation for intractable headache syndromes / Weiner, R.L. -- Peripheral nerve stimulation for occipital neuralgia: surgical leads / Kapural, L., Sable, J. -- Occipital nerve stimulation: technical and surgical aspects of implantation / Trentman, T.L., Zimmerman, R.S., Dodick, D.W. -- Peripheral neuromodulation for migraine headache / Ellens, D.J., Levy, R.M. -- Occipital neuromodulation for refractory headache in the chiari malformation population / Vadivelu, S., Bolognese, P., Milhorat, T.H., Mogilner, A.Y. -- Peripheral nerve stimulation in chronic custer headache / Magis, D., Schoenen, J. -- Peripheral nerve stimulation for fibromyalgia / Plazier, M. ... [et al.] -- Hybrid neurostimulator : simultaneous use of spinal cord and peripheral nerve field stimulation to treat low back and leg pain / Lipov, E.G. -- Stimulation of the peripheral nervous system for the painful extremity / McRoberts, W.P., Cairns, K.D., Deer, T. -- Sphenopalatine ganglion interventions: technical aspects and application / Oluigbo, C.O. ... [et al.] -- Spinal nerve root stimulation / Kellner, C.P., Kellner, M.A., Winfree, C.J. -- Technical aspects of peripheral nerve stimulation: hardware and complications / Slavin, K.V. -- Peripheral nerve stimulation: definition / Abejcentn, D., Perez-Cajaraville, J. -- The future of peripheral nerve stimulation / Stanton-Hicks, M. ... [et al.].
  • Personalized management of multiple sclerosis / Bianca Weinstock-Guttman, Murali Ramanathan & Robert Zivadinov -- Epidemiology and classification / Julia Pakpoor & Sreeram V. Ramagopalan -- Pathophysiology of multiple sclerosis : a controversial new perspective / Johannes M. van Noort & Sandra Amor -- Symptoms and diagnosis of multiple sclerosis / Eva Havrdová & Jana Lizrova Preiningerova -- Management of acute multiple sclerosis attacks / Finn T. Sellebjerg -- Disease-modifying treatments for relapsing-remitting multiple sclerosis / Per Soelberg Sørensen -- Disease-modifying treatments for secondary progressive and progressive relapsing multiple sclerosis / Laura J. Edwards & Cris Constantinescu -- Head-to-head versus therapy-change studies / Carlo Pozzilli & Luca Prosperini -- MRI as a surrogate marker for clinical outcomes in multiple sclerosis / Maria Pia Sormani -- Measurement of cerebral atrophy in multiple sclerosis / Ernst-Wilhelm Radue, Kerstin Bendfeldt & Till Sprenger -- Symptomatic therapy for multiple sclerosis / Scott E. Jarvis, Aaron Mackie & Luanne M. Metz -- Neurologic rehabilitation in multiple sclerosis / Susan E. Bennett -- Treatment of pediatric multiple sclerosis / Angelo Ghezzi -- Complementary and alternative treatments / Allen C. Bowling -- Future directions in multiple sclerosis / Anat Achiron -- Index.
  • PET and SPECT in Neurology highlights the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable to anybody in the field of neuroscience, from the neurologist and the radiologist/nuclear medicine specialist to the interested general practitioner and geriatrician. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.
  • PET and SPECT of Neurobiological Systems combines the expertise of renowned authors whose dedication to the development of novel probes and techniques for the investigation of neurobiological systems has achieved international recognition. Various aspects of neurotransmission in the brain are discussed, such as visualization and quantification of (more than 20 different) neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, -amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to anyone in the field of clinical or preclinical neuroscience, from the radiochemist and radiologist/nuclear medicine specialist to the interested neurobiologist and general practitioner. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences. Other volumes focus on PET and SPECT in psychiatry and PET and SPECT in "neurology".
  • Although more than 10 new antiepileptic drugs have been developed in the past decade, epilepsy remains resistant to drug therapy in about one-third of patients, many of whom struggle with the disease their entire lives. Managing these patients is a challenge and requires a structured multidisciplinary approach. The book includes chapters on all issues related to pharmacoresistance in epilepsy, and describes recent developments in the pathogenesis and treatment of this disorder. It addresses abnormalities in inhibitory mechanisms, epilepsy-related changes to the immune system, development of pharmacoresistance caused by chronic exposure to antiepileptic drugs, and novel therapeutic strategies for preventing or slowing down the progression of the disease. Clinicians and basic scientists alike will find up-to-date information on the development of pharmacoresistance, as well as reviews of mechanisms associated with epilepsy that may help them consider novel strategies for preventing the development of pharmacoresistance in the first place. The book also features information on new therapeutic strategies for control of epilepsy, such as transcutaneous electrical stimulation and virtual screening of new antiepileptic drugs. Pharmacoresistance in Epilepsy: From Genes and Molecules to Promising Therapies is useful to anyone working in the field, whether they're studying epilepsy in the lab or treating it in a doctor's office.
  • pt. 1. Foundations of phase response analysis -- pt. 2. Estimation of phase response curves -- pt. 3. Cellular mechanisms of neuronal phase response properties -- pt. 4. Prediction of network activity with phase response curves.
  • The Phosphatidylinositol 4-Kinases: Don't Call it a Comeback / Shane Minogue and Mark G. Waugh -- PIP Kinases from the Cell Membrane to the Nucleus / Mark Schramp, Andrew Hedman, Weimin Li, Xiaojun Tan and Richard Anderson -- The Phospholipase C Isozymes and Their Regulation / Aurelie Gresset, John Sondek and T. Kendall Harden -- Phosphoinositide 3-Kinases-A Historical Perspective / Alex Toker -- PI3Ks-Drug Targets in Inflammation and Cancer / Matthias Wymann -- Phosphoinositide 3-Kinases in Health and Disease / Alessandra Ghigo, Fulvio Morello, Alessia Perino and Emilio Hirsch -- Phosphoinositide Phosphatases: Just as Important as the Kinases / Jennifer M. Dyson, Clare G. Fedele, Elizabeth M. Davies, Jelena Becanovic and Christina A. Mitchell -- The PTEN and Myotubularin Phosphoinositide 3-Phosphatases: Linking Lipid Signalling to Human Disease / Nicholas R. Leslie, Elizabeth M. Davies, David A. Sheffield, Priyanka Tibarewal and Clare G. Fedele, et al.
  • Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol.
  • Part I. Overview of Chloride Transporters and Channels -- Part II. Current Methods for Studying Chloride Regulation -- Part III. From Cloning to Structure, Function and Regulation of Chloride Transporters and Channels -- Part IV. Cation-Chloride Cotransporters in Neural Function and Dysfunction -- Part V. Cation-Chloride Cotransport in Choroid Plexus and Blood-Brain Barrier.
  • Effect of Lifestyle, Aging, and Phytochemicals on the Onset of Neurological Disorders -- Beneficial Effects of Extra Virgin Olive Oil (n-9 Fatty Acids) on Neurological Disorders -- Beneficial Effects of Flaxseed Oil (n-3 Fatty Acids) on Neurological Disorders -- Beneficial Effects of Flavonoids on Neurological Disorders -- Beneficial Effects of Green Tea Catechins on Neurological Disorders -- Beneficial Effects of Curcumin on Neurological Disorders -- Beneficial Effects of Resveratrol on Neurological Disorders -- Beneficial Effects of Ginkgo biloba in Neurological Disorders -- Beneficial Effects of Garlic Components on Neurological Disorders -- Beneficial Effects of Propolis on Neurological Disorders -- Perspective and Direction for Future Research on Phytochemicals in Neurological Disorders.
  • Neck pain and shooting arm pain -- Shoulder pain -- Elbow pain -- Wrist and hand pain -- Low back pain, hip pain, and shooting leg pain -- Knee pain -- Ankle pain -- Foot pain.
  • This Pocket Reference offer a multifaceted guide on various aspects of Alzheimerℓ́ℓs disease. This thorough review discusses the challenges of diagnosis, different stages of the disease, testing, and current treatment methods, including pharmacological and nonpharmacological management of cognitive decline and symptoms due to Alzheimerℓ́ℓs disease. The book also has specific chapters on care issues for patients with Alzheimerℓ́ℓs disease, which describes what clinician's and caregivers should expect and how to manage the disease at its various stages. Additionally, the book provides helpful guides, tables, and tips for clinicians and caregivers to help care for the patient and the caregiver themselves.
  • Terms and Concepts -- History of the Key Disciplines -- Enviromics -- Genomics -- Epigenomics -- Molecular Phenomics -- Systems Phenomics -- Cohorts -- Challenges -- Personalized Preventive Medicine.
  • This book provides clear guidance on the prevention, early diagnosis, and treatment of positional plagiocephaly. Information is first presented on classification, epidemiology, and etiopathogenesis. Diagnosis is then explained in detail, covering the significance of anamnestic data, physical examination, differential diagnosis, instrumental examinations, and anthropometric measurements. Preventive measures such as 'tummy time' and physiotherapy are described, and the role of orthoses, osteopathy, and surgery in treatment is closely examined. The closing chapter addresses prognosis and complications. Positional plagiocephaly is not only a "cosmetic" problem but can cause facial and mandibular asymmetry, visual disturbances, and cognitive and psychomotor impairment, yet when correctly treated it usually resolves by 6-7 years of age. This book will be an ideal aid for pediatricians, neurosurgeons,maxillo-facial surgeons, orthopedic physicians, physiotherapists, and for all involved in preventing and managing the condition.
  • Post-traumatic stress disorder: definition, prevalence, and risk factors / Terence M. Keane, Brian P. Marx, and Denise M. Sloan -- The amygdala and the neural pathways of fear / Jacek Dębiec and Joseph LeDoux -- Physiology of the amygdala: implications for PTSD / Donald G. Rainnie and Kerry J. Ressler -- Counteracting molecular pathways regulating the reduction of fear: implications for the treatment of anxiety diseases / Andre Fischer and Li-Huei Tsai -- Memory in PTSD: a neurocognitive approach / Mieke Verfaellie and Jennifer J. Vasterling -- Toward animal models of post-traumatic stress disorder / Hagit Cohen and Gal Richter-Levin -- PTSD: from neurons to networks / Rajnish P. Rao ... [et al.] -- Arousal neurons in the brain / Priyattam J. Shiromani and Carlos Blanco-Centurion -- Hyperarousal and post-traumatic stress disorder: a role for the hypocretin system / Matt Carter and Luis de Lecea -- The locus coeruleus-noradrenergic system and stress: implications for post-traumatic stress disorder / Craig W. Berridge -- Effect of stress on sleep and its relationship to post-traumatic stress disorder / L.D. Sanford and X. Tang -- Stress hormones and PTSD / Rachel Yehuda -- Low basal cortisol and startle responding as possible biomarkers of PTSD: the influence of internalizing and externalizing comorbidity / Mark W. Miller, Erika J. Wolf, Laura Fabricant, and Nathan Stein -- Functional neuroimaging in post-traumatic stress disorder / Israel Liberzon and Sarah N. Garfinkel -- The amygdala in post-traumatic stress disorder / Lisa M. Shin -- Pharmacologic treatment of PTSD / Murray A. Raskind -- Guided imagery as a therapeutic tool in post-traumatic stress disorder / Jennifer L. Strauss, Patrick S. Calhoun, and Christine E. Marx -- Virtual reality exposure therapy for combat-related PTSD / Albert Rizzo ... [et al.].
  • "Practical Approach to Electroencephalography presents just enough detail, plus answers to common questions and problems - bringing even beginning readers to a highly sophisticated level of EEG interpretation. This guide goes beyond the basics of EEG interpretation, with and easy-to-understand explanation of the behaviour and electronics of EEG filters. Proper EEG terminology is explained and precisely defined. Abundant EEG examples throughout help you to recognize normal and abnormal EEGs in all situations."--BOOK JACKET.
  • Acknowledgements -- Preface -- Overview of headache in the emergency department -- Getting started -- Secondary headaches -- General treatment strategies -- Treating the child and adolescent with acute headache -- Treatment of pregnant and breastfeeding patients with acute headache in the ED -- Treatment of the older adult patient (>50 years old) with acute headache in the ED -- Managing risk in the ED -- After the ED: arranging post-ED follow-up care.
  • This simple guide to neurogenetics demystifies the overwhelming amount of information on the subject so you can identify key clinical features and understand your management options. Reach relevant differential diagnoses and provide appropriate counseling to your patients using the symptom-based approach. By integrating genetic and neurological approaches to diagnoses, this book ensures that the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis are clear and explicit. Concise and portable, this book is ideal for easy reference in clinical use. Details the underlying basic science and clinical features of genetic disorders by taking a symptom-based approach to provide you with a comprehensive understanding of the field. Focuses on the clinical application of neurogenetics to be of practical use to you in the clinic. Clarifies the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis by integrating genetic and neurological approaches to diagnoses. Discusses and evaluates necessary investigations so you know when to use them and when to refer. Highlights diagnostic and therapeutic tips so you can learn new concepts or refine your skills in practice. Refers to online sources, such as Online Mendelian Inheritance in Man (OMIM) and others, to help you supplement your knowledge.
  • 2011 ClinicalKey
    Practical Management of Pediatric and Adult Brachial Plexus Palsies covers in-depth surgical techniques for managing disorders of this crucial nerve complex so that you can most effectively treat injuries in patients of any age. Drs. Kevin Chung, Lynda Yan, and John McGillicuddy present a multidisciplinary approach to pediatric brachial plexus injury treatment and rehabilitation, obstetric considerations, and other hot topics in the field. With access to the full text and surgical videos online at, you'll have the dynamic, visual guidance you need to manage injuries to the brachial plexus. Access the fully searchable text online at, along with surgical videos demonstrating how to perform key procedures. See cases as they present in practice through color illustrations, photos, and diagrams that highlight key anatomical structures and relationships. Apply multidisciplinary best practices with advice from internationally respected authorities in neurosurgery, orthopaedics, plastic surgery, and other relevant fields. Hone your technique with coverage that emphasizes optimizing outcomes with pearls and discussions of common pitfalls. Prepare for collaborating with other physicians thanks to a multidisciplinary approach that covers medical and legal aspects in addition to surgery. Find information quickly and easily with a full-color layout.
  • Machine generated contents note: SECTION I Techniques and Safety -- 1.History and Introduction -- 2.Performing a Cerebral Arteriogram -- 3.Spinal Angiography: Technical Aspects -- 4.Pediatric Neuroangiography: Technical Aspects -- 5.Safety and Complications -- 6.Radiation Risks and Safety -- SECTION II Anatomy -- 7.Embryology of the Cranial Circulation -- 8.Aortic Arch -- 9.The Circle of Willis -- 10.The Internal Carotid Artery -- 11.The Anterior Cerebral Artery -- 12.The Middle Cerebral Artery -- 13.The Posterior Cerebral Artery -- 14.The Extradural Vertebral Arteries -- 15.The Arteries of the Posterior Fossa -- 16.The Venous System -- 17.The External Carotid Artery and Extracranial Circulation -- SECTION III Vascular Diseases: Diagnosis and Treatment -- 18.Intracranial Aneurysms, Diagnosis and Treatment -- 19.Vascular Malformation of the Brain -- 20.Cranial Dural Vascular Malformations -- 21.Vascular Malformations of the Spine -- 22.Pediatric Ischemic Stroke and Arteriopathy -- Contents note continued: 23.Carotid-Cavernous Fistulas -- 24.Nonaneurysmal Perimesencephalic Subarachnoid Hemorrhage -- 25.ENT Bleeding and Tumor Embolization -- 26.Reversible Cerebral Vasoconstriction Syndrome -- 27.Vasculitides Involving the Central Nervous System -- 28.Bow Hunter's Stroke -- 29.Dural Sinus Occlusive Disease -- 30.Cerebral Vasospasm -- 31.Angioplasty and Stenting of Atherosclerotic Disease -- 32.Endovascular Treatment of Ischemic Stroke -- 33.Vein of Galen Malformations.
  • Hypoxic-ischemic brain damage / Alejandro A. Rabinstein and Steven Resnick -- Clinical-anatomical syndromes of ischemic infarction / Alejandro A. Rabinstein and Steven Resnick -- Acute stroke imaging / Alejandro A. Rabinstein and Steven Resnick -- Cardiac embolism / Alejandro A. Rabinstein and Steven Resnick -- Extracranial large artery atherothrombosis / Sebastian Koch -- Intracranial atherosclerotic disease / Jose G. Romano -- Small vessel disease / Alejandro A. Rabinstein and Steven Resnick -- Uncommon causes of stroke / Alejandro A. Rabinstein and Steven Resnick -- Spinal cord infarction / Alejandro A. Rabinstein and Steven Resnick -- Spontaneous intraparenchymal hemorrhage / Alejandro A. Rabinstein and Steven Resnick -- Secondary intraparenchymal hemorrhages / Alejandro A. Rabinstein and Steven Resnick -- Subarachnoid hemorrhage / Alejandro A. Rabinstein and Steven Resnick -- Vascular anomalies of the brain / Nils Mueller-Kronast -- Cerebral venous thrombosis / Alexander Y. Zubkov, Steven Resnick, and Alejandro A. Rabinstein.
  • A volume in the new Pattern Recognition series- offers you a practical guide to solving the problems you encounter in the surgical reporting room. Drs. Arie Perry and Daniel J. Brat present diagnoses according to a pattern-based organization that guides you from a histological pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Lavish illustrations capture key neuropathological patterns for a full range of common and rare conditions, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance. No other single source delivers the practical, hands-on information you need to solve even the toughest diagnostic challenges in neuropathology.
  • Emotional, behavioral, and neuropsychiatric conditions are common in individuals with intellectual disabilities (IDs), most notably epilepsy, aggression, self-injurious behaviors, and bipolar and other mood disorders. Despite the prevalence of such problems, there is a scarcity in the literature of reliable information on medical treatments for those with IDs. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities provides a detailed framework for prescribing for this challenging population. Featuring the most up-to-date information on factors that inform prescribing, the Guide addresses basic issues and controversies (e.g., the rift between evidence-based and personalized medicine) in treating adults with cognitive deficits. Clients' specific needs are emphasized in developing appropriate and effective pharmacological intervention for improved outcomes and quality of life. Drugs discussed in the Guide include carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, Â tiagabine, topiramate, valproate, and zonisamide. For each of these compounds, the guidelines cover:Indications for use; relative and absolute contraindications. Assessment during treatment; therapeutic drug monitoring; warning signs and symptoms for caretakers. Dosage: administration; initial and maximum recommended dosage; modifications associated with drug-drug interactions, personal characteristics, and (where appropriate) genetic variations. Adverse drug reactions: common, relatively uncommon, and potentially lethal, plus risk of metabolic syndrome. Guidelines for discontinuation. References, tables, and drug utilization reviews. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities is an indispensable decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and clinical psychologists.
  • Prefrontal cortex. 4th ed. 2008
    Chapter 1. Introduction -- Chapter 2. Anatomy of the Prefrontal Cortex -- Chapter 3. Chemical Neurotransmission -- Chapter 4. Animal Neuropsychology -- Chapter 5. Human Neuropsychology -- Chapter 6. Neurophysiology -- Chapter 7. Neuroimaging -- Chapter 8. Overview of Prefrontal Functions: The Temporal Organization of Action.
  • Prevention of stroke 2002
  • Epidemiology and risk factors -- Molecular pathogenesis -- Cellular origins of malignant glioma: the cancer stem cell polemic -- Principles of supportive care -- Principles of clinical trial design and response assessment -- Complications of therapy -- Neuropsychological function and quality of life -- Low-grade gliomas -- High-grade astrocytomas -- Anaplastic oligodendrogliomas and mixed gliomas -- Ependymomas -- Uncommon gliomas in adults: brainstem gliomas, pilocytic astrocytomas, and pleomorphic xanthastrocytomas -- Pediatric tumors -- Primary central nervous system lymphoma -- Meningiomas -- Pituitary adenomas -- Vestibular schwannomas -- Medulloblastomas -- Pineal region tumors -- Genetic syndromes -- Rare tumors -- Spinal tumors.
  • Immunology for the Non-immunologist -- Neurology for the Non-neurologist -- Neuroimmunology for the Non-neuroimmunologist -- The Prototypic Neuroimmunological CNS Disease: Multiple Sclerosis, a Precis -- Multiple Sclerosis: Diagnosis -- Multiple Sclerosis Mimics -- Multiple Sclerosis Therapy -- Experimental Models of MS -- Guillain-Barré Syndrome (GBS) and Other Immune-Mediated Neuropathies -- Neuromuscular Neuroimmunological Diseases: Myasthenia Gravis -- The Prototypic Neuroimmunological Muscle Disease: Dermatomyositis -- A Introduction to Neurological Infections: Neuro-infectious Disease as Part of Neuroimmunology -- Neurological Manifestations of Systemic Chronic Inflammatory Disease -- The Neuroimmunology of Cancer: Paraneoplastic Syndromes and Primary CNS Lymphoma -- Neuroimmunology of Degenerative Diseases and Stroke -- Important Rare Neuroimmunological Diseases -- Neuroimmunological Molecules and Translational Medicine -- Neuroimmunological Diagnostic Tests -- Therapy in Neuroimmunological Disease.
  • 2011 ClinicalKey
    Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables.
  • The molecular basis of intervertebral disc degeneration / Leo, B.M.; Walker, M.H.; Anderson, D.G. -- Genetics of degenerative disc disease / Kurpad, S.N.; Lifshutz, J. -- Gene therapy for degenerative disc disease / Kim, J.; Gilbertson, L.G.; Kang, J.D. -- Bone morphogenetic proteins: spinal fusion applications / Bomback, D.A.; Grauer, J.N. -- Cellular and gene therapy approaches to spinal cord injury / Steinmetz, M.P.; Liu, J.K.; Boulis, N.M. -- Neural stem cell transplantation for spinal cord repair / Iwanami, A. ... [et al.] -- Contemporary applications of functional and stereotactic techniques for molecular neurosurgery / Couldwell, W. -- Xeno-neurotransplantation / Schumacher, J.M. -- Molecular mechanisms of epilepsy and gene therapy / Telfeian, A.; Celix, J.; Dichter, M. -- Adeno-associated viral (AAV) vectors for clinical gene therapy in the brain / Samulski, R.J. -- Molecular mechanisms of epilepsy and gene therapy / Telfeian, A.; Celix, J.; Dichter, M. -- Emerging treatment of neurometabolic disorders / Brady, R.O.; Brady, R.O. Jr. -- Gene therapy for Parkinson's disease / Hadaczek, P.; Daadi, M.; Bankiewicz, K. -- Simplifying complex neurodegenerative diseases by gene chip analysis / Scherzer, C.R.; Gullans S.R.; Jensen, R.V. -- Molecular pathology of dementia: emerging treatment strategies / Gouras, G.K. -- Expanding the role of deep brain stimulation from movement disorders to other neurological disorders / Leone, M. ... [et al.] -- Molecular mediators of pain / Chaudhary P.; Burchiel, K. -- Gene transfer in the treatment of pain / Fink, D.; Mata, M.; Glorioso, J.C. -- Gene discovery underlying stroke / Barone, F.C.; Read, S.J. -- Molecular mediators of hemorrhagic stroke / Macdonald, R.L. -- Advances towards cerebrovascular gene therapy / Watanabe, Y.; Heistad, D.D. -- Ex vivo gene therapy and cell therapy for stroke / Kondziolka, D.; Sheehan, J.; Niranjan, A. -- Neurosurgical applications for polymeric drug delivery systems / Wang, P.P.; Brem, H. -- Immunotherapy strategies for treatment of malignant gliomas / Harshyne, L.; Flomenberg, P.; Andrews, D.W. -- 'Glioma-genesis': signaling pathways for the development of molecular onco-therapy / Kapoor, G.S.; O'Rourke, D.M. -- Oncolytic viral therapy for glioma / Lamfers, M.L.M.; Visted, T.; Chiocca, E.A. -- Molecular neurosurgery in the pituitary gland: gene transfer as adjunctive treatment strategy -- Castro, M.G. ... [et al.] -- Stem cells for targeting CNS malignancy / Yip, S.; Sidman, R.L.; Snyder, E.Y.
  • Understanding how populations of neurons encode information is the challenge faced by researchers in the field of neural coding. Focusing on the many mysteries and marvels of the mind has prompted a prominent team of experts in the field to put their heads together and "fire up" a book on the subject. Simply titled Principles of Neural Coding, this book covers the complexities of this discipline. It centers on some of the major developments in this area and presents a complete assessment of how neurons in the brain encode information. The book's collaborators contribute various chapters that describe results in different systems (visual, auditory, somatosensory perception, etc.) and different species (monkeys, rats, humans, etc.). The introductory chapters concentrate on the recording and analysis of the firing of single and multiple neurons as well as the analysis and recording of other integrative measures of network activity and network states, such as local field potentials or current source densities. The book then moves forward with a description of the principles of neural coding for different functions and in different species and concludes with theoretical and modeling works describing how information processing functions are implemented. The text not only contains the most important experimental findings, but gives an overview of the main methodological aspects for studying neural coding. In addition, the book describes alternative approaches based on simulations with neural networks and in silico modeling in this highly interdisciplinary topic. It can serve as an important reference to students and professionals.
  • 2012 ClinicalKey
    Part 1.General Overview . Landmarks in the History of Neurosurgery / James Tait Goodrich ; Clinical Evaluation of the Nervous System / Gerald A. Grant, Richard G. Ellenbogen ; Principles of Modern Neuroimaging / Kathleen R. Tozer Fink, Michael R. Levitt, James R. Fink ; Principles of Surgical Positioning / Genèvieve Lapointe, Joanna Kemp, Govind Rajan, Grace Elisabeth Walter, Saleem I. Abdulrauf. -- Part 2.Pediatric Neurosurgery. Spinal Dysraphism and Tethered Spinal Cord / Leslie N. Sutton, Joel A. Bauman, Luke J. Macyszyn ; Hydrocephalus in Children and Adults / Alia Hdeib, Alan R. Cohen ; Developmental Anomalies: Arachnoid Cysts, Dermoids, and Epidermoids / David F. Jimenez, Jennifer Gentry Savage, Mical Samuelson ; Diagnosis and Surgical Options for Craniosynostosis / Mitchel Seruya, Suresh N. Magge, Robert F. Keating ; The Chiari Malformations and Syringohydromyelia / R. Shane Tubbs, Todd C. Hankinson, John C. Wellons, III ; Posterior Fossa and Brainstem Tumors in Children / Adrienne Weeks, Aria Fallah, James T. Rutka ; Causes of Nontraumatic Hemorrhagic Stroke in Children: Pediatric Moyamoya Syndrome / Edward R. Smith, R. Michael Scott. -- Part 3.Vascular Neurosurgery. Cerebrovascular Occlusive Disease and Carotid Surgery / Geoffrey Appelboom, Matthew Piazza, E. Sander Connolly, Jr. ; Intracranial Aneurysms / Christopher S. Eddleman, Christopher C. Getch, Bernard R. Bendok, H. Hunt Batjer ; Vascular Malformations (Arteriovenous Malformations and Dural Arteriovenous Fistulas) / Ghaus M. Malik, Sandeep S. Bhangoo ; Cavernous Malformations Management Strategies / Aimee Two, Ali K. Ozturk, Murat Gunel ; Spontaneous Intracerebral Hemorrhage / Alan Hoffer, Justin Singer, Nicholas C. Bambakidis, Warren Selman ; Endovascular Neurosurgery / Sabareesh K. Natarajan, Adnan H. Siddiqui, L. Nelson Hopkins, Elad I. Levy ; Cerebral Revascularization for Giant Aneurysms of the Transitional Segment of the Internal Carotid Artery / Jonathon J. Lebovitz, Jorge L. Eller, Justin M. Sweeney, Deanna Sasaki-Adams, Aneela Darbar, Sheri K. Palejwala, Anja-Maria Radon, Saleem I. Abdulrauf. -- Part 4.Trauma. Intracranial Hypertension / Ryan Morton, Richard G. Ellenbogen ; Closed Head Injury / Clifford M. Houseman, Shawn A. Belverud, Raj K. Narayan ; Penetrating Brain Injury / Michael Cirivello, Randy S. Bell, Rocco A. Armonda ; Traumatic Skull and Facial Fractures / Fred H. Geisler, Eduardo Rodriguez, Paul N. Manson. -- Part 5.Spine. Injuries to the Cervical Spine / M. Yashar S. Kalani, Aristotelis S. Filippidis, Nicholas Theodore ; Thoracolumbar Spine Fractures / Edward M. Marchan, George M. Ghobrial, James S. Harrop ; Intradural Extramedullary and Intramedullary Spinal Cord Tumors. / Michaël Bruneau, Florence Lefranc, Danielle Balériaux, Jacques Brotchi ;Treatment of Spinal Metastatic Tumors / Ilya Laufer, Marcella A. Madera, Daniel Sciubba, Ziya L. Gokaslan ; Spinal Cord Injury / David W. Cadotte, Michael G. Fehlings ; Syringomyelia / Spyros Sgouros ; Craniovertebral Junction: A Reappraisal / Atul Goel ; Degenerative Spine Disease / James K.C. Liu, Edward C. Benzel ; Pediatric and Adult Scoliosis / David W. Polly, Jr., A. Noelle Larson (Part I) Frank Schwab, Benjamin Blondel, Virginie Lafage (Part II) ; Acute Nerve Injuries / Lynda J-S Yang ; Entrapment Neuropathies / Mikhail Gelfenbeyn, Henry Marsh. -- Part 6.Tumors. Low-Grade and High-Grade Gliomas / Nader Sanai, Mitchel S. Berger ; Metastatic Brain Tumors / Juanita M. Celix, Daniel L. Silbergeld ; Meningiomas / Federico Landriel, Peter Black ; Tumors of the Pineal Region / Christian Matula ; Cerebellopontine Angle Tumors / Madjid Samii, Venelin M. Gerganov ; Craniopharyngiomas and Suprasellar Tumors / Juraj ten¿o ; Pituitary Tumors: Diagnosis and Management / Carrie R. Muh, Nelson M. Oyesiku ; Endoscopic Approaches to Ventricular Tumors and Colloid Cysts / Scott D. Wait, Charles Teo ; Microsurgical Approaches to the Ventricular System / Timothy H. Lucas, II, Richard G. Ellenbogen ; Skull Base Approaches / Salvatore Di Maio, Laligam N. Sekhar ; Endoscopic Approaches to Skull Base Lesions, Ventricular Tumors, and Cysts / Nancy McLaughlin, Daniel M. Prevedello, Daniel Kelly, Ricardo L. Carrau, Amin B Kassam, Scott D. Wait, Charles Teo, Aneela Darbar, Sheri K. Palejwala. -- Part 7.Radiosurgery. Application of Current Radiation Delivery Systems and Radiobiology / Jay Loeffler, Helen Shih, Melin Khandekar ; Radiosurgery of Central Nervous System Tumors / Douglas Kondziolka, Ajay Niranjan, L. Dade Lunsford, John C. Flickinger ; Stereotactic Radiosurgery of Vascular Malformation / Chun Po Yen, Chris Cifarelli, David Schlesinger, Jason P. Sheehan. -- Part 8.Functional/Pain. Trigeminal Neuralgia / Gerald A. Grant, John D. Loeser ; Surgical Therapy for Pain / Giovanni Broggi, Francesco Acerbi, Morgan Broggi, Giuseppe Messina / Spasticity: Classification, Diagnosis, and Management / Michael R. Levitt, Samuel R. Browd ; Surgery for Temporal Lobe Epilepsy / Jeffrey G. Ojemann, Carlo Giussani, Carlo Marras ; Extratemporal Procedures and Hemispherectomy for Epilepsy / Gwyneth Hughes, William Bingaman ; Basic Principles of Deep Brain Stimulation for Movement Disorders, Neuropsychiatric Disorders, and New Frontiers / Alexander S. Taghva, Chima O. Oluigbo, Ali R. Rezai. -- Online only: E44 Minimal Access Skull Base Approaches / Paolo Cappabianca, Isabella Esposito, Luigi Maria Cavallo, Felice Esposito, Vita Stagno.
  • 1. Introduction to the Operating Room -- 2. Anatomy of Intraoperative Monitoring -- 3. Cellular Neurophysiology -- 4. Electrophysiology and Bioinstrumentation -- 5. Anesthesiology and Intraoperative Electrophysiological Monitoring -- 6. Somatosensory Evoked Potential Monitoring -- 7. Motor Evoked Potentials -- 8. Electromyography (EMG) -- 9. Brainstem Auditory Evoked Potentials -- 10. Electroencephalography -- 11. The H-Reflex and F-Response -- 12. Monitoring Procedures of the Spine -- 13. Intraoperative Monitoring for Surgery of the Spinal Cord and Cauda Equina -- 14. Monitoring Posterior Fossa Craniotomies -- 15. Intraoperative Monitoring for Carotid Endarterectomy -- 16. Monitoring for ENT Procedures -- 17. Peripheral Nerve Monitoring -- 18. Intraoperative Cortical Mapping: Basic Concepts, Indications, and Anesthesia Considerations -- 19. Neurological Assessment and Correlation in Spinal Cord Nerve Root Pathology -- 20. Electrophysiological Assessment of Spinal Cord Pathology in Pain Medicine -- 21. Spinal Cord Stimulation: Principles and Applications -- 22. New Vistas: Small-Pain-Fibers Method of Testing for Spinal Cord Assessment in Pain States.
  • Introduction and theoretical foundations / Sara A. Lawless, Julie K. Ries, and Antolin M. Llorente -- American population estimates, trends in American immigration, and neuropsychology : influences on assessment and inferential processes with Hispanic populations / Antolin M. Llorente -- Hispanic populations : special issues in neuropsychology / Antolin M. Llorente -- Intellectual abilities : theoretical and applied assessment considerations / Christian von Thomsen, Lori Gallup, and Antolin M. Llorente -- Language : development, bilingualism, and abnormal states / Christine French and Antolin M. Llorente -- The neuropsychological assessment of the Hispanic client / Antolin M. Llorente and Deborah Weber -- Hispanics and cultural bias : test development and applications / Peter Smith, Eric Lane, and Antolin M. Llorente -- Rehabilitation / Julie K. Ries, Brian Potter, and Antolin M. Llorente.
  • Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer's disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume covers history from the high Middle Ages to the TSE era of Daniel Carleton Gajdusek, followed by the prion era of Stanley Prusiner whose extraordinary discovery opened a new chapter in prion research. Volume I will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.
  • Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.
  • A survival guide to solving diagnostic challenges that are particularly problematic in neuroimaging. With a concise, practical, and instructional approach, it helps apply basic principles of problem solving to imaging of the head and interventional neck, brain, and spine. Inside, you'll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy, percutaneous drainage, and tumor ablation. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today's best practices at your fingertips, including protocols for optimizing the most state-of-the-art imaging modalities. A full-color design, including more than 700 high-quality images, highlights critical elements to enhance your understanding. Apply expert tricks of the trade and protocols for optimizing the most state-of-the-art imaging modalities and their clinical applications used for the brain and spine-with general indications for use and special situations. Make the most efficient use of modern imaging modalities including multidetector CT, PET, advanced MR imaging/MR spectroscopy (MRS), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), and perfusion weighted imaging (PWI). Successfully perform difficult interventional techniques such as biopsies of the spine and interventional angiography-key techniques for more accurately diagnosing cerebral vascular disease, aneurysm, and blood vessel malformations-as well as percutaneous drainage and tumor ablation. Know what to expect. A dedicated section is organized by the clinical scenarios most likely to be encountered in daily practice, such as neurodegenerative disease, vascular disease, and cancer. Avoid common problems that can lead to an incorrect diagnosis. Tables and boxes with tips, pitfalls, and other teaching points show you what to look for, while problem-solving advice helps you accurately identify what you see-especially those images that could suggest several possible diagnoses. See conditions as they appear in practice thanks to an abundance of case examples and specially designed full-color, high-quality images which complement the text and highlight important elements.
  • The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed the experimental landscape and opened new possibilities. The advances in PSC have provided an important tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled environment. For example, reprogramming cells from patients with neurological diseases allows the study of molecular pathways particular to specific subtypes of neurons such as dopaminergic neurons in Parkinson.s Disease, Motor neurons for Amyolateral Sclerosis or myelin for Multiple Sclerosis. In addition, because PSC technology allows for the study of human neurons during development, disease-specific pathways can be investigated prior to and during disease onset. Detecting disease-specific molecular signatures in live human brain cells, opens possibilities for early intervention therapies and new diagnostic tools. Importantly, it is now feasible to obtain gene expression profiles from neurons that capture the genetic uniqueness of each patient. Importantly, once the neurological neural phenotype is detected in vitro, the so-called "disease-in-a-dish" approach allows for the screening of drugs that can ameliorate the disease-specific phenotype. New therapeutic drugs could either act on generalized pathways in all patients or be patient-specific and used in a personalized medicine approach. However, there are a number of pressing issues that need to be addressed and resolved before PSC technology can be extensively used for clinically relevant modeling of neurological diseases.
  • Progress in brain research v. 1-, 1963-
  • "This volume is the most recent installment of the Progress in Motor Control series. It contains contributions based on presentations by invited speakers at the Progress in Motor Control IX meeting held in at McGill University, Montreal, in July, 2013. Progress in Motor Control is the official scientific meeting of the International Society of Motor Control (ISMC). The Progress in Motor Control IXI meeting, and consequently this volume, provide a broad perspective on the latest research on motor control in humans and other species"--Publisher's description.
  • Model-based and model-free mechanisms of human motor learning / Adrian M. Haith, John W. Krakauer -- The molecular basis of experience-dependent motor system development / Robert G. Kalb, Weiguo Zhou, Lei Zhang -- Neurocognitive mechanisms of error-based motor learning / Rachael D. Seidler ... [et al.] -- Plasticity in the motor network following primary motor cortex lesion / Numa Dancause -- The mirror system in monkeys and humans and its possible motor-based functions / Leonardo Fogassi, Luciano Simone -- A molecular basis for intrinsic muscle properties : implications for motor control / Kiisa C. Nishikawa ... [et al.] -- Theoretical and methodological issues in serial correlation analysis / Didier Delignières, Vivien Marmelat -- On the control of unstable objects : the dynamics of human stick balancing / Ramesh Balasubramaniam -- Intermittent motor control : the "drift-and-act" hypothesis / John G. Milton.
  • Progressive multiple sclerosis places a huge burden on individuals, carers and society and treatment options are currently limited. However, there have been significant recent advances in understanding progressive disease and this book draws the field together into a single, accessible, clinically focused text. Progressive Multiple Sclerosis sets out the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. The biological processes underlying disease progression are elucidated as are specific pathophysiological mechanisms. The basic science of axonal degeneration and the clinical understanding of progressive multiple sclerosis are discussed in the context of emerging and future therapies for disease progression as are trials which might be conducted for progressive multiple sclerosis. An overview of biomarkers for the disease is included and existing symptomatic therapies for progressive multiple sclerosis are covered in detail. Each chapter addresses specific aspects of progressive multiple sclerosis providing an extensive review of the current literature and a discussion of the likely mechanisms of tissue injury relevant to the disease. Progressive Multiple Sclerosis is ideal for both general neurologists and those with a specialist interest in multiple sclerosis. It will also be of interest to neurologists in training and other medical professionals treating this common disease. Dr Alastair Wilkins is Senior Lecturer in Neurology, University of Bristol, and Consultant Neurologist at Frenchay Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.
  • Protein folding and misfolding, relevance to disease, and biological function / Massimo Stefani -- Alzheimer's disease / Charlotte E. Teunissen and Tischa J.M. van der Cammen -- Improving cholinergic transmission -- Cholinergic transmission and acetylcholine release enhancers / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- AChE and its inhibition / Jure Stojan -- AChE inhibitors and their clinical assessment / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- Reduction in plaque formation -- Secretase and APP processing / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Mechanism of plaque formation and A[B] aggregation inhibitors / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Nonsteroidal anti-inflammatory drugs / Bruno P. Imbimbo and Francesca Speroni -- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors / Dario Cattaneo -- A[B] polymerization reduction / Harry LeVine III and Corrine E. Augelli-Szafran -- Carbonic anhydrase activators as potential anti-Alzheimer's disease agents / Claudiu T. Supuran and Andrea Scozzafava -- Detection and reduction of neurofibrillary lesions / Jeff Kuret -- Protein misfolding in Alzheimer disease : pathogenic or protective? / Rudy J. Castellani ... [et al.] -- Enhancement of brain retinoic acid levels / Ann B. Goodman ... [et al.] -- Parkinson's disease : what is it? what causes it? and how can it be cured? / Tom Foltynie, Andrew W. Michell, and Roger A. Barker -- Restoring dopamine levels / P. Nuno Palma .. [et al.] -- Huntington's disease / Claire-Anne Gutekunst and Fran Norflus -- Amyotrophic lateral sclerosis (motor neuron disease) / Teresa Sanelli ... [et al.] -- Transmissible spongiform encephalopathies / Michael D. Geschwind and Giuseppe Legname -- Overview / H. John Smith, Robert D.E. Sewell, and Claire Simons.
  • The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
  • The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans, and appears to occur many years before the onset of clinical symptoms. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer's disease, has increasingly implicated corruptive protein templating, or seeding, as a prime factor in the neurodegenerative process. The prion-like corruption of proteins also characterizes such clinically and etiologically diverse neurological disorders as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration. Understanding the misfolding, aggregation, trafficking and pathogenicity of affected proteins thus could reveal universal principles and common therapeutic targets for some of the most devastating and intractable human brain disorders.
  • Neurosphere and Neural Colony-Forming Cell Assays / Sharon A. Louis, Brent A. Reynolds -- Directed Neuronal Differentiation of Embryonic and Adult-Derived Neurosphere Cells / Marcos R. Costa, Ravi Jagasia, Benedikt Berninger -- Culture and Differentiation of Human Neural Stem Cells / Soojung Shin, Mohan Vemuri -- Neural Differentiation of Human Embryonic Stem Cells / Mirella Dottori, Alice Pébay, Martin F. Pera -- Isolation and Culture of Primary Human CNS Neural Cells / Manon Blain, Veronique E. Miron, Caroline Lambert, Peter J. Darlington, Qiao-Ling Cui, Philippe Saikali, V. Wee Yong, Jack P. Antel -- Bioengineering Protocols for Neural Precursor Cell Expansion / Behnam A. Baghbaderani, Arindom Sen, Michael S. Kallos, Leo A. Behie -- Intracellular Calcium Assays in Dissociated Primary Cortical Neurons / Navjot Kaur, David V. Thompson, David Judd, David R. Piper, Richard G. Del Mastro -- Dissociated Hippocampal Cultures / Francine Nault, Paul Koninck -- Primary Sensory and Motor Neuron Cultures / Andrea M. Vincent, Eva L. Feldman -- Retinal Cell and Tissue Culture / Francisco L.A.F. Gomes, Michel Cayouette -- Preparation of Normal and Reactive Astrocyte Cultures / Jean Vellis, Cristina A. Ghiani, Ina B. Wanner, Ruth Cole -- Oligodendrocyte Progenitor Cell Culture / Akiko Nishiyama, Ryusuke Suzuki, Hao Zuo, Xiaoqin Zhu -- Isolation of Microglia Subpopulations / Makoto Sawada, Hiromi Suzuki -- Microglia from Progenitor Cells in Mouse Neopallium / Sergey Fedoroff, Arleen Richardson -- Primary Schwann Cell Cultures / Haesun A. Kim, Patrice Maurel -- Primary Dissociated Astrocyte and Neuron Co-culture / Shelley Jacobs, Laurie C. Doering -- Cerebellar Slice Cultures / Josef P. Kapfhammer -- Hippocampal Slice Cultures / Jesse E. Hanson, Adrienne L. Orr, Silvia Fernandez-Illescas, Ricardo A. Valenzuela, Daniel V. Madison -- Molecular Substrates for Growing Neurons in Culture / Saulius Satkauskas, Arnaud Muller, Morgane Roth, Dominique Bagnard -- Guidance and Outgrowth Assays for Embryonic Thalamic Axons / Alexandre Bonnin -- Detection of Cell Death in Neuronal Cultures / Sean P. Cregan -- Live Imaging of Neural Cell Functions / Sabine Bavamian, Eliana Scemes, Paolo Meda -- Tissue Culture Procedures and Tips / Arleen Richardson, Sergey Fedoroff.
  • Epidemiology of psychiatric symptoms in Parkinson's Disease -- Depression, apathy and anxiety disorders -- Apathy in Parkinson's Disease -- Disorders of visual perception in Parkinson's Disease and other Lewy body disorders -- Psychosis and Parkinson's Disease -- Sleep in Parkinson's Disease and dementia with Lewy bodies -- Sexual problems in Parkinson's Disease -- An update on impulse control disorders in Parkinson's Disease -- Neuropsychological features of early cognitive impairment in Parkinson's Disease -- Parkinson's Disease with dementia -- Somatoform disorders in Parkinson's Disease and dementia with Lewy bodies evidence underlying psychotic traits -- Drug-induced Parkinsonism and abnormal involuntary movements.
  • Psychosurgery, or the surgical treatment of mental disorders, has enjoyed a spectacular revival over the past ten years as new brain stimulation techniques have become available. Neuromodulation offers new possibilities for the treatment of psychiatric disorders such as depression, obsessive-compulsive disorder (OCD), addiction, eating disorders and autism. This work presents the history of this unique specialty and investigates current techniques and ethical challenges. With a wealth of illustrations and detailed anatomical diagrams, it provides essential information for medical practitioners, as well as anyone else interested in the fascinating advances being made in neuroscience today.
  • Introduction -- Early History of Purinergic Signalling -- Purinergic Cotransmission -- Mechanisms of ATP Release and Inactivation -- Receptors for Purines and Pyrimidines -- Evolution of Purinergic Signalling -- Peripheral Nervous System -- Purinergic Signalling in the Central Nervous System -- Sensory Nerves -- Special Senses -- Ontogeny of Purinergic Neurotransmission.
  • Orofacial pain : a challenge and chance (not only) for dentistry / Turp, J.C., Hugger, A., Sommer, C. -- Characteristics of muscle nociception / Mense, S. -- Nociceptors of the joint with particular reference to silent nociceptors / Schaible, H.-G. -- Inflammatory mediators in temporomandibular joint pain / Kopp, S., Sommer, C. -- The role of reproductive hormones in orofacial pain / LeResche, L. -- Pathophysiology of orofacial pain / Sessle, B. -- Dental pain : pathophysiology and management / Khan, A.A., Hargreaves, K.M. -- Myofascial temporomandibular disorder pain : pathophysiology and management / Schindler, H.J., Svensson, P. -- Painful arthrogenous temporomandibular disorders : pathophysiology, diagnosis, management and prognosis / Steenks, M.H., Hugger, A., de Wijer, A. -- Neuralgic and idiopathic facial pain : pathophysiology and management / Sommer, C. -- Burning mouth syndrome : pathophysiology and management / Zakrzewska, J., Renton, T. -- Psychosocial impact of orofacial Pain / Dworkin, S.F. -- A rationale for the classification of orofacial pain / Woda, A. -- Orofacial pain: past and future / Greene, C.S. -- The end of an era: orofacial pain enters the genomic age : implications and opportunities for research and the care of patients / Stohler, C.S.
  • Key methodological issues -- Distress/protection vulnerability model of quality of life impairment syndrome -- Role of dopamine in pleasure, reward and subjective responses to drugs -- Neuroendocrine functions,mood and quality of life -- In the mind of the beholder neuronal mediators for the effect of emotional experience on quality of life -- Cross-cultural quality of life research in mental health -- Measuring the value of health-related quality of life -- Comparison of instruments for measuring the quality of life impairment syndrome in severe mental disorders -- Integrative bottom-up approach to HRQQL measurement -- Quality of life impairment syndrome in severe mental disorders -- Health related quality of life in subjects at risk for a first episode of psychosis -- Quality of life impairment syndrome in schizophrenia -- Insight and quality of life in schizophrenia spectrum disorders -- Quality of life and major depression -- Quality of life impairment in bipolar disorder -- Quality of life impairment in anxiety disorders -- Quality of life in obsessive-compulsive disorder -- Treatment and rehabilitation issues -- Antipsychotic medications, schizophrenia and the issue of quality of life -- Quality of life outcomes of ECT -- Quality of life in mental health services -- Subjective quality of life in relation to psychiatric rehabilitation and daily life -- Cost-utility analysis.
  • Neural anatomy -- Passive membranes -- Active membranes -- Propagation -- Neural branches -- Synapses -- Networks of neurons -- Extracellular recording and stimulation -- The neural code -- Applications.
  • Section I. Animal models of PD -- Chapter 1. What have we learned from Drosophila models of Parkinson's disease? / Ming Guo -- Chapter 2. Neurotoxic in vivo models of Parkinson's disease: recent advances / Jason R. Cannon, J. Timothy Greenamyre -- Chapter 3. Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease / Stephen B. Dunnett, Mariah Lelos -- Chapter 4. Genetic mouse models of Parkinson's disease: The state of the art / Iddo Magen, Marie-Françoise Chesselet -- Chapter 5. Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease / Ayse Ulusoy, Mickael Decressac, Deniz Kirik, Anders Björklund -- Chapter 6. Modeling neuroinflammatory pathogenesis of Parkinson's disease / Christopher J. Barnum, Malú G. Tansey -- Chapter 7. The MPTP-lesioned non-human primate models of Parkinson's disease. Past, present, and future / Susan H. Fox, Jonathan M. Brotchie -- Section II. Exploring PD with brain imaging. -- Chapter 8. Abnormal metabolic brain networks in Parkinson's disease: from blackboard to bedside / Chris C. Tang, David Eidelberg -- Chapter 9. Imaging the nigrostriatal system to monitor disease progression and treatment-induced complications / Renju Kuriakose, A. Jon Stoessl -- Chapter 10. Brain imaging after neural transplantation / Marios Politis, Paola Piccini -- Chapter 11. Imaging non-motor aspects of Parkinson's disease / David J. Brooks, Nicola Pavese -- Section III. Frontiers in PD treatment -- Chapter 12. Gene therapy for dopamine replacement / Tomas Björklund, Erik Ahlm Cederfjäll, Deniz Kirik -- Chapter 13. Neurotrophic factor therapy for Parkinson's disease / Suresh Babu Rangasamy, Katherine Soderstrom, Roy A.E. Bakay, Jeffrey H. Kordower -- Chapter 14. Neural grafting in Parkinson's disease: Problems and possibilities / Patrik Brundin, Roger A. Barker, Malin Parmar -- CHAPTER 15. Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia / Emma L. Lane, Anders Björklund, Stephen B. Dunnett, Christian Winkler -- Chapter 16. Deep brain stimulation: state of the art and novel stimulation targets / Francisco A. Ponce, Andres M. Lozano -- Chapter 17. The challenge of non-motor symptoms in Parkinson's disease / K. Ray Chaudhuri, Per Odin.
  • Section I. Genetic and molecular mechanisms of neurodegeneration in PD -- Chapter 1. Identifying PD-causing genes and genetic susceptibility factors: Current approaches and future prospects / Thomas Gasser -- Chapter 2. The impact of genetic research on our understanding of Parkinson's disease / Ian Martin, Valina L. Dawson, Ted M. Dawson -- Chapter 3. Unravelling the role of defective genes / Mark R. Cookson -- Chapter 4. What causes the death of dopaminergic neurons in Parkinson's disease? / D. James Surmeier, Jaime N. Guzman, Javier Sanchez-Padilla, Joshua A. Goldberg -- Chapter 5. Intracellular signalling pathways in dopamine cell death and axonal degeneration / Robert E. Burke -- Chapter 6. Control of mitochondrial integrity in Parkinson's disease / Cristofol Vives-Bauza, Maja Tocilescu, Rosa L.A. deVries, Dana M. Alessi, Vernice Jackson-Lewis, Serge Przedborski -- Chapter 7. Role of post-translational modifications in modulating the structure, function and toxicity of α-synuclein: Implications for Parkinson's disease pathogenesis and therapies / Abid Oueslati, Margot Fournier, Hilal A. Lashuel -- Section II. Cellular and system-level pathophysiology of the basal ganglia in PD -- Chapter 8. The role of dopamine in modulating the structure and function of striatal circuits / D. James Surmeier, Weixing Shen, Michelle Day, Tracy Gertler, Savio Chan, Xianyong Tian, Joshua L. Plotkin -- Chapter 9. Assemblies of glutamate receptor subunits with post-synaptic density proteins and their alterations in Parkinson's disease / Fabrizio Gardoni, Veronica Ghiglieri, Monica di Luca, Paolo Calabresi -- Chapter 10. Pathophysiological roles for purines: Adenosine, caffeine and urate / Micaela Morelli, Anna R. Carta, Anil Kachroo, Michael A. Schwarzschild -- Chapter 11. Maladaptive striatal plasticity in l-DOPA-induced dyskinesia / M. Angela Cenci, Christine Konradi -- Chapter 12. Effects of GPi and STN inactivation on physiological, motor, cognitive and motivational processes in animal models of Parkinson's disease / Christelle Baunez, Paolo Gubellini -- Chapter 13. Computational physiology of the basal ganglia in Parkinson's disease / Michal Rivlin-Etzion, Shlomo Elias, Gali Heimer, Hagai Bergman -- Chapter 14. Neurocomputational models of motor and cognitive deficits in Parkinson's disease / Thomas V. Wiecki, Michael J. Frank.
  • Frontiers of spinal cord and spine repair : experimental approaches for repair of spinal cord injury / Choya Yoon and Mark H. Tuszynski -- Stem cell based strategies for spinal cord injury repair / Alexa Reeves and Hans S. Keirstead -- Strategies for endogenous spinal cord repair : HPMA hydrogel to recruit migrating endogenous stem cells / Araceli Espinosa-Jeffrey ... [et al.] -- Stem cells and spinal cord injury repair / Soheila Karimi-Abdolrezaee and Eftekhar Eftekharpour -- Chronic pain following spinal cord injury / Radi Masri and Asaf Keller -- Repair of radiation damage and radiation injury to the spinal cord / Timothy E. Schultheiss -- Malignancies of the spinal cord / J. Dawn Waters, Encarnacion Maria Navarro Peran, and Joseph Ciacci -- Molecular basis of intervertebral disc degeneration / Dipika Gopal ... [et al.] -- Bioceramics for osteogenesis, molecular and cellular advances / Hande Demirkiran -- Cell-based therapies for spinal fusion / Ronke Olabisi -- Clinical efficacy of stem cell mediated osteogenesis and bioceramics for bone tissue engineering / Josh Neman ... [et al.] -- Progenitor cells : role and usage in bone tissue engineering approaches for spinal fusion / Lonnissa H. Nguyen ... [et al.].
  • Introduction -- Adaptation and contraction theory for the synchronization of complex neural networks -- Temporal coding is not only about cooperation, it is also about competition -- Using non-oscillatory dynamics to disambiguate pattern mixtures -- Functional constraints on network topology via generalized sparse -- Evolution of time in neural networks, from the present to the past, and forward to the future -- Synchronization of coupled pulse-type hardware neuron models for CPG model -- A univesal abstract-time platform for real-time neural networks -- Solving complex control tasks via simple rule(s), using chaotic dynamics in a recurrent neural network model -- Time scale analysis of neuronal ensemble data used to feed neural network models -- Simultaneous EEG-fMRI, integrating spatial and temporal resolution -- Erratum to: Time scale analysis of neuronal ensemble data used to feed neural network models.
  • Repetitive transcranial magnetic stimulation (rTMS) treatment is increasingly being used in the management of patients with depression. Since the approval of one rTMS device in the United States in 2008, clinical services using this equipment have become relatively common there, and services are also being developed in a variety of other countries. However, considerable ignorance exists about the treatment in general psychiatric practice. This concise clinical guide will serve as a reference and practical tool for clinicians working with or learning about this treatment technique. The opening chapters provide basic information on the history and development of rTMS treatment and its mechanism of action. Use of the treatment in depression is then addressed in detail, with explanation of the evidence base and discussion of clinical issues such as selection of patients and type of treatment, dose, and treatment duration. Side-effects of treatment are explored, and careful consideration is given to various practical issues concerning the establishment of rTMS treatment programs and the training of clinicians. The final chapters will provides a brief overview of potential rTMS applications in other psychiatric conditions and some background on the use of related treatments, such as transcranial direct current stimulation.
  • Restless legs syndrome 2009
    Introduction -- General introduction: Restless Legs Syndrome as a neurological conundrum -- Patient's perspective -- From 1685 to 2008: an introduction to Restless Legs Syndrome -- Restless Legs Syndrome as a movement disorder -- Restless Legs Syndrome and nocturnal myoclonus (periodic limb movements during sleep) -- Clinical science of Restless Legs Syndrome -- Basic science of Restless Legs Syndrome -- Epidemiology and genetics -- Epidemiology of Restless Legs Syndrome -- Genetics of Restless Legs Syndrome -- Pathophysiology -- Iron metabolic system -- Iron dysregulation in Restless Legs Syndrome -- Brain's dopaine systems and their relevance to Restless Legs Syndrome -- Neuroimaging in Restless Legs Syndrome -- Circadian rhythm of Restless Legs Syndrome -- Spinal cord, dopamine, opiates, and Restless Legs Syndrome -- Clinical science of Restless Legs Syndrome -- Diagnosis -- Diagnosis of Restless Legs Syndrome -- Differential diagnosis of Restless Legs Syndrome -- Periodic limb movements in sleep -- Sleep laboratory diagnosis of Restless Legs Syndrome -- Actigraph assessment of periodic leg movements and Restless Legs Syndrome -- Assessment of Restless Legs Syndrome features with standardized methods -- Comorbidities and special populations -- Restless Legs Syndrome and periodic limb movement disorder in childhood and adolescence -- Restless Legs Syndrome and pregnancy -- Restless Legs Syndrome and periodic limb movements in the elderly with and without dementia -- Restless Legs Syndrome in medical disorders -- Restless Legs Syndrome in neurological disorders -- Is the manifestation of the Restless Legs Syndrome related to a pain mechanism? -- Restless Legs Syndrome and psychiatric disorders -- Management -- Introduction to management of Restless Legs Syndrome -- Nonpharmacological considerations and treatment of Restless Legs Syndrome -- Dopaminergic therapy of Restless Legs Syndrome -- Opioid agents in the treatment of Restless Legs Syndrome -- Anticonvulsants in the treatment of Restless Legs Syndrome -- Iron treatment -- Additional agents and miscellaneous therapies -- Management of Restless Legs Syndrome in the hospital and during surgery -- Restless Legs Syndrome morbidity: sleep and quality of life -- History of the Restless Legs Syndrome Foundation.
  • Decisions -- The injury -- Coming to terms with brain injury -- The origins of the vegetative state -- A shift since Quinlan -- Maggie's wishes -- Something happened in Arkansas -- From PVS to MCS -- Leaving the hospital -- Heather's story -- Neuroimaging and neuroscience in the public mind -- Contractures and contradictions : medical necessity and the injured brain -- Minds, monuments, and moments -- Heads and hearts, toil and tears -- What do families want? -- Deep brain stimulation in MCS -- Mending our brains, minding our ethics -- It's still freedom -- Maggie's in town -- When consciousness becomes prosthetic -- The rights of mind -- A call for advocacy.
  • The RNA infrastructure : an introduction to ncRNA networks / Lesley J. Collins -- RNA interactions / Manja Marz and Peter F. Stadler -- Plant RNA silencing in viral defence / Vitantonio Pantaleo -- Micrornas as post-transcriptional machines and their interplay with cellular networks / Sarath Chandra Janga and Swathi Vallabhaneni -- Spatiotemporal aspects of microRNA-mediated gene regulation / Joris Pothof and Dik C. van Gent -- Spliceosomal RNA infrastructure : the network of splicing components and their regulation by miRNAs / Lesley J. Collins -- Construction, structure, and dynamics of post-transcriptional regulatory network directed by RNA binding proteins / Sarath Chandra Janga and Nitish Mittal -- Safe keeping the message : mRNP complexes tweaking after transcription / Said Hafidh, Věra Čapková, and David Honys -- Unexpected functions of tRNA and tRNA processing enzymes / Rebecca L. Hurto -- Programmed DNA elimination in tetrahymena : a small RNA mediated genome surveillance mechanism / Kensuke Kataoka and Kazufumi Mochizuki -- Long noncoding RNA and epigenomics / Chandrasekhar Kanduri -- Promoter associated long noncoding RNAs repress transcription through a RNA binding protein TLS / Riki Kurokawa -- RNA networks in prokaryotes I :CRISPRs and riboswitches / Patrick J. Biggs and Lesley J. Collins -- RNA networks in prokaryotes II : tRNA processing and small RNAs / Lesley J. Collins and Patrick J. Biggs -- Localization of the bacterial RNA infrastructure / Kenneth C. Keiler -- Small RNA discovery and characterisation in eukaryotes using high throughput approaches / Helio Pais ... [et al.] -- How old are RNA networks? / Toni Daly, X. Sylvia Chen, and David Penny.
  • Coma, head trauma, and spinal cord injury / Galen V. Henderson -- Epilepsy / Edward B. Bromfield and Barbara A. Dworetzky -- Dizziness / Robert W. Baloh -- Back and neck pain / Allan H. Ropper -- Sleep disorders / Milena Pavlova -- Neurooncology / Patrick Y. Wen and Santosh Kesari -- Multiple sclerosis and other demyelinating diseases / Maria K. Houtchens and David M. Dawson -- Motor neuropathies and peripheral neuropathies / Anthony A. Amato -- Neuromuscular junction disorders and myopathies / Anthony A. Amato -- Chronic pain / Robert D. Helme -- Headache and facial pain / Elizabeth Loder and Paul Rizzoli -- Stroke and cerebrovascular disorders / Steven K. Feske -- Movement disorders / Lewis Sudarsky -- Behavioral neurology and dementia / Kirk R. Daffner and David A. Wolk -- Neuroophthalmology / Marc J. Dinken and Don C. Bienfang -- Toxic and metabolic disorders / Martin A. Samuels -- Infections of the central nervous system / Tracey A. Cho.
  • Scientific neurological basis for assessment -- Introductory scientific history to neuropsychological assessment -- Nature of science -- Theoretical foundation of neurological assessment -- Neuropsychological basis of assessment -- Brain-function analysis -- Formal analytic methodology -- Neuropsychological battery patterns -- Justification of formal procedures -- Fundamental psychometric status of neuropsychological batteries -- Justification of neuropsychological batteries -- Accuracy of formal neuropsychological methods -- Application to forensics -- Admissibility of neuropsychological expert testimony under the Daubert and Frye evidentiary standards -- Usefulness of a validated neuropsychological test battery is scientifically supporting and communicating forensic evaluation results -- Formal neuropsychological methods -- In defense of the Halstead-Reitan Battery: a critique of Lezak's review -- In defense of the Halstead-Reitan Battery: revisited -- Norming subjects for the Halstead-Reitan Battery -- Major Halstead-Reitan Battern norm sets.
  • Chapter 1- Epidemiology of Seizures and Epilepsy in Cerebrovascular Disease -- Chapter 2: Seizures in Ischemic Stroke -- Chapter 3: Seizures in Intracerebral Hemorrhage -- Chapter 4: Seizures in Subarachnoid Hemorrhage -- Chapter 5: Seizures in subdural hematoma -- Chapter 6: Seizures in Cerebral Cavernous Malformations -- Chapter 7: Seizures in Arteriovenous Malformations -- Chapter 8: Seizures in Cerebral Venous Sinus Thrombosis -- Chapter 9: Pediatric Stroke and Seizures -- Chapter 10: Medical Management of Seizures in Cerebrovascular Disorders.
  • Presentation and pathophysiology of seizures in the critical care environment: an overview -- Diagnosing and monitoring seizures in the ICU: the role of continuous EEG for detection and management of seizures in critically ill patients -- Stroke and critical care seizures -- Traumatic brain injury and seizures in the ICU -- Brain tumors and ICU seizures -- Global hypoxia-ischemia and critical care seizures -- Seizures in fulminant hepatic failure, multiorgan failure, and endocrine crisis -- Seizures in organ transplant recipients -- Extreme hypertension, eclampsia and critical care seizures -- Infection or inflammation and ICU seizures -- Electrolyte disturbances and critical care seizures -- Alcohol-related seizures in the intensive care unit -- Drug-induced seizures in critically ill patients -- Critical care seizures related to illicit drugs and toxins -- Management of status epilepticus and critical care seizures.
  • Sensory nerves 2009
  • "Sensory perception : mind and matter aims at a deeper understanding of the many facets of sensory perception and their relations to brain function and cognition. It is an attempt to promote the interdisciplinary discourse between the neurosciences and psychology, which speaks the language of cognitive experiences, and philosophy, which has been thinking about the meaning and origin of consciousness since its beginning. Leading experts contribute to such a discourse by informing the reader about exciting modern developments, both technical and conceptual, and by pointing to the big gaps still to be bridged. The various chapters provide access to scientific research on sensory perception and the mind from a broad perspective, covering a large spectrum of topics which range from the molecular mechanisms at work in sensory cells to the study of the unconscious and to neurophilosophy"--Publisher.
  • Quantitative imaging of serotonin autofluorescence with multiphoton microscopy / S.K. Kaushalya and Sudipta Maiti -- Monitoring receptor-mediated changes of intracellular cAMP level by using ion channels and fluorescent proteins as biosensors / Evgeni G. Ponimaskin ... [et al.] -- Membrane organization and dynamics of the serotonin1A receptor monitored using fluorescence microscopic approaches / Shanti Kalipatnapu, Thomas J. Pucadyil, and Amitabha Chattopadhyay -- Calmodulin is a 5-HT receptor interacting and regulatory protein / Justin N. Turner ... [et al.] -- Identification of novel transcriptional regulators in the nervous system / Federico Remes-Lenicov ... [et al.] -- Serotonin 2A (5-HT2A) receptor function: ligand-dependent mechanisms and pathways / Ishier Raote, Aditi Bhattacharya, and Mitradas M. Panicker -- The 5-HT1A receptor: a signaling hub linked to emotional balance / Probal Banerjee, Mukti Mehta, and Baishali Kanjilal -- Do limits of neuronal plasticity represent an opportunity for mental diseases, such as addiction to food and illegal drugs? Use and utilities of serotonin receptor knock-out mice / Valerie Compan -- Use of mice with targeted genetic inactivation in the serotonergic system for the study of anxiety / Miklos Toth.
  • Section I. General Overview -- Chapter 1. Sex differences in brain anatomy / Eileen Luders, Arthur W. Toga -- Chapter 2 . Sex differences in the human brain: A developmental perspective / Tomáš Paus -- Chapter 3. Sex influences on brain and emotional memory: The burden of proof has shifted / Larry Cahill -- Chapter 4. Sexual differentiation of the human brain in relation to gender identity and sexual orientation / Ivanka Savic, Alicia Garcia-Falgueras, Dick F. Swaab -- Section II. The Mechanisms Behind Sex Dimorphism in the Brain -- Chapter 5. Genes and brain sex differences / Francisco J. Sánchez, Eric Vilain -- Chapter 6. Genetic and epigenetic underpinnings of sex differences in the brain and in neurological and psychiatric disease susceptibility / Irfan A. Qureshi, Mark F. Mehler -- Chapter 7. Gene expression in neuroendocrine cells during the critical period for sexual differentiation of the brain / Khatuna Gagnidze, Donald W. Pfaff, Jessica A. Mong -- Chapter 8. Neurosteroids: Endogenous role in the human brain and therapeutic potentials / Doodipala Samba Reddy -- Section III. Clinical Implications -- Chapter 9. Sex and gender differences in pain and analgesia / Jeffrey S. Mogil, Andrea L. Bailey -- Chapter 10. The skewed sex distribution in affective disorders: A diagnostic, social, or biological problem? / Marianne J. Legato -- Chapter 11. Empathizing, systemizing, and the extreme male brain theory of autism / Simon Baron-Cohen -- Chapter 12. Gender and the injured brain / Paco S. Herson, Patricia D. Hurn.
  • Lomb's algorithm and the Hilbert transform -- Modeling -- Volterra series -- Wiener series -- Poisson-Wiener series -- Decomposition of multichannel data -- Causality.
  • Sleep and aging. 1st ed. 2005
  • GABA[subscript A] receptor subtypes in sedation and hypnosis / Esa R. Korpi -- Sleep hippocampal theta rhythm and sensory processing / Marisa Pedemonte and Ricardo A. Velluti -- Monoaminergic mechanisms in the regulation of sleep-wakefulness: special emphasis on preoptic noradrenergic system / Vijay Ramesh and Velayudhan Mohan Kumar -- REM sleep function and brain monoamine regulation: an application of the search activity concept / Vadim S. Rotenberg -- Role of wakefulness area in the brainstem reticular formation in regulating rapid eye movement sleep / Birendra N. Mallick ... [et al.] -- The mechanistic relationship between NREM sleep and anesthesia / Laura E. Nelson, Nicholas P. Franks, and Mervyn Maze -- Time-dependent psychotropic drug effects: hints of pharmacochronomics, broader than circadian time structures / Haruo Nagayama ... [et al.] -- Melatonin interaction with BZ-Gaba[subscript A] receptors: implications for sleep induction / Lennard P. Niles -- Melatonin: a chronobiotic that not only shifts rhythms / Dieter Kunz and Richard Mahlberg -- Melatonin and human sleep / Irina V. Zhdanova -- Melatonin efficacy to treat circadian alterations of sleep in Alzheimer's disease / Daniel P. Cardinali ... [et al.] -- Pharmacotherapy for seasonal affective disorder / Timo Partonen -- Use and discontinuation of hypnosedative medications / Mirko Petrovic -- Long-term use of sleeping pills in chronic insomnia / Milton Kramer -- Risks of chronic hypnotic use / Daniel F. Kripke -- Effects of psychotropics on driving performance / Henry J. Moller, Colin M. Shapiro, and Leonid Kayumov -- Diagnosis, pathophysiology and treatment of hypersomnias / Sebastiaan Overeem and Michel Billiard -- Chronic disease and sleep architecture pharmacotherapeutic considerations / James J. Herdegen -- Benzodiazepines for sedation in infants and children / Eugene Ng and Vibhuti Shah -- The pharmacological management of fatigue and sleepiness in affective disorders / Karl Doghramji -- Next-day residual effects of sleeping medications on driving ability: a review of the literature / Joris C. Verster, Marinus N. Verbaten, and Edmund R. Volkerts -- Sleep and pain / Wilfred R. Pigeon, Hyung Park, and Michael J. Sateia -- Head injuries and sleep / Chanth Seyone and Babita Kara -- Psychopharmacological management of restless legs syndrome and periodic limb movements in sleep / Raed Hawa ... [et al.] -- A comparison of visual analog scale and categorical ratings in assessing the patient's estimate of sleep quality / Nava Zisapel, Ricardo Tarrasch, and Moshe Laudon -- The pharmacostrategy of treating sleep disorders in Parkinsonism / Jean-Jacques Askenasy -- The neuropharmacology of nightmares / J.F. Pagel -- The night eating syndrome / Grethe Seta Birketvedt and Jon R. Florholmen -- Drug effects on dreaming / Mehmet Yucel Agargun and Hanefi Ozbek -- Sleep problems in primary care / Alan G. Wade -- SSRIs and sleep in man / Sue J. Wilson and David J. Nutt -- Sleep and antipsychotic drugs in schizophrenia patients / Jaime M. Monti and Daniel Monti -- Sleep and epilepsy: from interrelationships to influence of antiepileptic drugs / Antonio Martins da Silva ... [et all.] -- Herbal medicines and sleep / Marcello Spinella.
  • Electrical stimulation of the upper airways muscles / Randerath, W.J. -- Cardiac pacemaker therapy in sleep apnea / Schichtl, T., Pfeifer, M. -- Surgical treatment for obstructive sleep apnea / Boudewyns, A.N., Van de Heyning, P.H. -- Alternative therapies for obstructive sleep apnea syndrome : behavioral and pharmacological options / Smith, I.E. -- Central sleep apnea, hypoventilation syndromes, and periodic breathing disorders / Caples, S.M., Somers, V.K. -- Cardiovascular complications of sleep-related breathing disorders / Naughton, M.T., Sanner, B.M. -- Sleep-related breathing disorders in children / Amin, R.S. ... [et al.] -- Sleep-related breathing disorders in the elderly / Cooke, J.R., Ancoli-Israel, S. -- Sleep-disordered breathing in pregnancy / Sullivan, C.E., Edwards, N. Obstructive sleep apnea-hypopnea syndrome definitions of pathophysiology / De Backer, W. -- Oxidative stress--the culprit of obstructive sleep apnea syndrome / Lavie, L., Lavie, P. -- Genetics aspects of the obstructive sleep apnea/hypopnea syndrome / Riha, R.L. -- Upper airway muscles in obstructive respiratory sleep disorders / Svanborg, E. -- Obstructive sleep apnea : clinical presentation, diagnosis, and treatment / Yim, S., Jordan, A., Malhotra, A. -- Automatic positive airway pressure titration and treatment / Randerath, W.J. -- Treatment humidification in sleep-related breathing disorders / Benjafield, A.V., Richards, G.N. -- Oral appliances in the treatment of obstructive sleep apnea and snoring / Marklund, M. Sleep disorders and their classification--an overview / Lévy, P., Viot-Blanc, V., Pépin, J.-L -- Physiology of sleep and dreaming / Penzel, T., Kesper, K. -- Physiology of breathing during sleep / Schäfer, T. -- Physiology of the cardiovascular, endocrine, and renal systems during sleep / Peter, J.G., Fietze, I. -- History and questionnaires / Rühle K.-H. -- Objectifying sleepiness / Hein, H. -- Portable monitoring systems / Hein, H. -- Polysomnography / Penzel, T. -- Nasal, lung, and cardiovascular function tests / Galetke, W. -- Upper airway imaging in sleep apnea syndrome / Pinto Basto, R., Rodenstein, D.O. -- Upper airway obstruction in snoring and upper airway resistance syndrome / Kirkness, J.P. ... [et al.].
  • Sleep physiology -- Extent and health consequences of chronic sleep loss and sleep disorders -- Functional and economic impact of sleep loss and sleep-related disorders -- Improving awareness, diagnosis, and treatment of sleep disorders -- Ensuring adequate diagnosis and treatment : access, capacity, and technology development -- Opportunities to improve career development in somnology -- Bolstering somnology and sleep disorders research programs -- Building sleep programs in academic health centers.
  • Sleep disorders. Part I-II pt. 1-2, 2011.
    pt. 2, 2011 ScienceDirect
  • Circadian Clock Genes and the Regulation of Sleep / Thomas Curie and Paul Franken -- Clock Genes and Energy Metabolism / Hee-Kyung Hong, Wenyu Huang, Kathryn Moynihan Ramsey, Biliana Marcheva and Joseph Bass -- Neural Circuitry Responsible for Sleep and Wakefulness / Roda Rani Konadhode, Dheeraj Pelluru and Priyattam J. Shiromani -- Feeding as a Reward Mechanism / Ralph J. DiLeone, Nandakumar S. Narayanan and Douglas J. Guarnieri -- Plasticity of Brain Feeding Circuits in Response to Food / Tamas Horvath -- The Neurogenetics of Energy Balance / Martin G. Myers Jr. -- Short Sleep and Obesity Risk in Children / Chantelle N. Hart, Elizabeth S. Kuhl and Elissa Jelalian -- Circadian Misalignment and Sleep Disruption in Shift Work: Implications for Fatigue and Risk of Weight Gain and Obesity / Rachel R. Markwald and Kenneth P. Wright Jr. -- Sleep Apnea and Obesity / Vidya Krishnan and Sanjay R. Patel -- The Connection Between Sleep Loss, Obesity, and Type 2 Diabetes / Silvana Pannain, Guglielmo Beccuti and Eve Van Cauter -- Sleep Disturbances: Impact on Risk and Severity of Diabetes / Kelly A. Holes-Lewis -- Insufficient Sleep and Cardiovascular Disease / Susan Redline -- Clinical Guidelines for the Evaluation of Adults with Obstructive Sleep Apnea / Lawrence J. Epstein -- Pharmacological Treatment of Obesity / Dhiraj G. Kabra, Uma D. Kabra, Matthias H. Tschöp and Susanna Hofmann -- Bariatric Surgery for Treatment of Obesity / Mark J. Perna, Thomas Karl Byrne and Chitharanja C. Pullattrana.
  • A new addition to the Neurology in Practice series, Sleep Medicine in Neurology is a practical guide for neurologists diagnosing and managing sleep disorders in their patients. As a part of the series, various feature boxes are highlighted throughout. ""Tips and Tricks"" give suggestions on how to improve outcomes through practical technique or patient questioning. In addition, ""Caution"" warning boxes supply helpful advice on how to avoid problems and 'Science Revisited' boxes offer quick reminders of the basic science principles necessary for understanding the presented concepts.
  • Behavioral and electrophysiological correlates of sleep and sleep homeostasis -- Genetic dissection of sleep homeostasis -- Sleep deprivation and gene expression -- Sleep and synaptic homeostasis -- Sleep and synaptic plasticity in the developing and adult brain -- Sleep and adult neurogenesis: implications for cognition and mood -- Animal studies on the role of sleep in memory: from behavioral performance to molecular mechanisms -- A bird's eye view of sleep-dependent memory consolidation -- Neuroimaging studies of sleep and memory in humans -- The role of sleep in human declarative memory consolidation -- Sleep-dependent memory consolidation in healthy aging and mild cognitive impairment -- Adenosine, caffeine, and performance: from cognitive neuroscience of sleep to sleep pharmacogenetics -- Optogenetic control of hypocretin (orexin) neurons and arousal circuits -- Stress, arousal, and sleep -- Sleep and emotional functions -- Sleep and plasticity in schizophrenia -- Chronically restricted or disrupted sleep as a casula factor in the development of depression -- Sleep deprivation therapy for depression -- Pharmacological treatment of sleep disorders and its relationship with neuroplasticity -- Index.
  • "Human Impact Assessment (HuIA) is a relatively new concept describing an integrated process that encompasses both Health Impact Assessment and Social Impact Assessment and is used to anticipate the effects of programs, projects and decisions on human health and welfare. Sleep occupies approximately one-third of our lives, but its human impact remains largely unrecognized. The prevalence of excessive sleepiness is recognized to be increasing in industrialized societies. Sleepiness and fatigue have high costs in terms of both lives lost and socioeconomic impact. Sleepiness and Human Impact Assessment provides a comprehensive exploration of many different facets of sleepiness in our 24-hour society from the new HuIA point of view. Among the covered issues are the physiology and pathophysiology of sleep, its relationship to daytime alertness, fatigue and drugs, the relevance of sleep-related fatigue in various occupational settings and public safety. This book will be of assistance to physicians, occupational health professionals, ergonomists, researchers and decision-makers as they strive to understand the full significance of sleepiness and to create a culture of accountability in everyday life without sleep-related risks."--Publisher's website.
  • Slow oscillations in perspective and in detail -- Slow brain oscillations of sleep, resting, state, and vigilance -- Electrophysiological correlates of sleep homeostasis in freely behaving rats -- Involvement of cytokines in slow wave sleep -- Sleep and resting state EEG-profile as heritable endophenotype and during development -- Genetic determination of sleep EEG profiles in healthy humans -- Developmental aspects of sleep slow waves: linking sleep, brain maturation and behavior -- Phasic events during slow oscillations -- Phasic modulation of cortical high-frequency oscillations by pedunculopontine neurons -- Slow oscillations orchestrating fast oscillations and memory consolidation -- Spontaneous neural activity during human non-rapid eye movement sleep -- Thalamocortical and cortico-hippocampal network interactions during slow sleep oscillations -- Neuronal plasticity and thalamocortical sleep and waking oscillations -- Infraslow (<0.1 Hz) oscillations in thalamic relay nuclei: basic mechanisms and significance to health and diseaes states -- Hippocampal-cortical interactions and the dynamics of memory trace reactivation -- Cortica synchronization and travelling of slow oscillations -- Long-range correlation of the membrane potential in neocortical neurons during slow oscillation -- Temporal dynamics of cortical sources underlying spontaneous and peripherally evoked slow waves -- Functional beliefs of slow oscillations during sleep -- Sleep and developmental plasticity: not just for kids -- Evoked electrical and cerebral vascular responses during sleep and following sleep deprivation -- Reduction of nocturnal slow-wave activity affects daytime vigilance lapses and memory encoding but not reaction time or implicit learning -- Infraslow oscillations in resting state network activity during sleep and wakefulness -- Spectral characteristics of resting state networks -- Modulation of the brain's functional network architecture in the transition from wake to sleep -- Spontaneous fMRI activity during resting wakefulness and sleep -- Infraslow oscillations, consciousness and performance -- Hypnotic modulation of resting state mMRI default mode and extrinsic network connectivity -- Multimodal neuroimaging in patients with disorders of consciousness showing functional hemispherectomy -- Roles of multiscale brain activity fluctuations in shaping the variability and dynamics of psychophysical performance.
  • "Planning, conducting, and publishing the results of your clinical research can be a long and arduous journey. The SMART Approach to Spine Clinical Research presents and explains the many interrelated components essential to spine clinical research in an easily accessible way, guiding you step-by-step through the principles and methods of planning and evaluating clinical research."--Cover.
  • Sobotta - Atlas of Human Anatomy: the exam atlas for understanding, learning, and training anatomy The English-language Sobotta Atlas with English nomenclature is specifically adapted to the needs of preclinical medical students. Right from the start, the book and the Internet content concentrate on exam-relevant knowledge. The new study concept simplifies learning-understanding-training: Descriptive legends help the student identify the most important features in the figures. Clinical examples present anatomical details in a wider context. All illustrations have been optimized, and the lettering reduced to a minimum. Volume 3 "Head, Neck and Neuroanatomy" includes the following topics: HeadEyeEarNeckBrain and Spinal Cord.
  • "The study of mathematical cognition and the ways in which the ideas of space, time and number are encoded in brain circuitry has become a fundamental issue for neuroscience. How such encoding differs across cultures and educational level is of further interest in education and neuropsychology. This rapidly expanding field of research is overdue for an interdisciplinary volume such as this, which deals with the neurological and psychological foundations of human numeric capacity. A uniquely integrative work, this volume provides a much needed compilation of primary source material to researchers from basic neuroscience, psychology, developmental science, neuroimaging, neuropsychology and theoretical biology."--Publisher's description.
  • Cerebral palsy detection : from John Little to the present / Giovanni Cioni, Paola B. Paolicelli -- Guide to the interpretation of cerebral palsy / Adriano Ferrari, Silvia Alboresi -- Functional diagnosis in infants and in very young children : early predictive signs / Giovanni Cioni, Andrea Guzzetta, Vittorio Belmonti -- Motor defects / Adriano Ferrari -- Perceptive defects / Adriano Ferrari -- Praxic organization disorders / Simonetta Muzzini, Federico Posteraro, Roberta Leonetti -- Visual and oculomotor disorders / Andrea Guzzetta ... [et al.] -- Neuropsychological evaluation / Daniels Brizzolara, Paola Brovedani, Giovanni Ferretti -- Emotional, behavioral and social disorders in children and adolescents with cerebral palsy / Gabriele Masi, Paolo Brovedani -- Observing interactions / Sandra Maestro -- Critical aspects of classifications / Adriano Ferrari -- Kinematic classification / Adriano Ferrari -- Tetraplegic forms / Adriano Ferrari ... [et al.] -- Dysperceptive forms / Silvia Alboresi ... [et al.] -- Forms of diplegia / Adriano Ferrari ... [et al.] -- Forms of hemiplegia / Giovanni Cioni ... [et al.].
  • The organization of the spinal cord / Charles Watson and Gulgun Kayalioglu -- Development of the spinal cord / Kens WS Ashwell -- The vertebral column and spinal meninges / Gulgun Kayalioglu -- The spinal nerves / Gulgun Kayalioglu -- The spinal cord blood vessels / Oscar U. Scremin -- Cytoarchitecture of the spinal cord / Claire Heise and Gulgun Kayalioglu -- Localization of motoneurons in the spinal cord / Steve McHanwell and Charles Watson -- Spinal autonomic preganglionic neurons: the visceral efferent system of the spinal cord / Colin R. Anderson, Janet R. Keast and Elspeth M. McLachlan -- Central nervous system control of micturition / Gert Holstege and Han Collewijn -- Projections from the spinal cord to the brain / Gulgun Kayalioglu -- Projections from the brain to the spinal cord / Charles Watson and Alan R. Harvey -- The propriospinal system / Amanda C. Conta and Dennis J. Stelzner -- Spinal cord transmitter substances / Claire Heise and Gulgun Kayalioglu -- Spinal cord injury: experimental animal models and relation to human therapy / Stuart I. Hodgetts, Giles W. Plant and Alan R. Harvey -- Atlas of the rat spinal cord / Charles Watson ... [et al.] -- Atlas of the mouse spinal cord / Charles Watson ... [et al.] -- Toward a spinal cord ontology / Charles Watson and Amandeep Sidhu.
  • Spinal cord injury 2012
    Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury. Comprehensive coverage of the latest scientific understanding of spinal cord injuries Detailed coverage of current treatment best practices and potential future treatments Connects leading edge research programs to future treatment opportunities .
  • Section I. Spinal cord injuries in patients -- Section II. Spinal cord injuries in animal models -- Section III. Neuroprotection and transplantation -- Section IV. Molecular targets to promote axon regeneration in the CNS.
  • Spinal imaging 2008
    Thieme Book
    1. Congenital malformations -- Arnold-Chiari malformation -- Lumbarization and sacralization -- Diastematomyelia -- Tethering -- Sacrococcygeal teratoma -- Meningocele, myelomeningocele -- Vertebral malformations -- Klippel-Feil syndrome -- Kyphosis -- Scheuermann disease -- Scoliosis -- Malrotation -- 2. Trauma -- Spinal injury-magerl classification -- Vertebral fractures-causes -- Dens fracture -- Flexion fracture of the cervical spine -- Burst fracture of the spine -- Chance fracture (seat belt fracture) -- Jefferson fracture -- Hangmans's fracture -- Spinal cord trauma -- Syringohydromyelia -- Anterior subluxation -- Insufficiency fracture of the sacrum -- Stress phenomena in the spine -- Stress fractures in ankylosing spondylitis -- 3. Degenerative disorders -- Disk degeneration -- Degenerative disk disease modic I -- Degenerative disk disease modic II -- Spondylosis deformans-modic III -- Disk herniation -- Bulge, protrusion, extrusion, sequestration -- Disk calcification and vacuum phenomenon -- Facet joint degeneration -- Uncovertebral osteoarthritis -- Synovial cyst -- Hypertroply of the ligamenta flava -- Baastrup disease -- Spongylolisthesis and pseudospondylolisthesis -- Degenerative spinal stenosis -- Diffuse idiopathic skeletal hyperostosis -- 4. Inflammatory disorders -- Rheumatoid arthritis -- Rheumatoid arthritis-chronic trauma -- Psoriatic spondyloarthropathy -- Reiter syndrome -- Ankylosing spondylarthropathy -- Ankylosing spondylitis-ligament calcification and bamboo spine -- Ankylosing psondylitis-fractures --Acute bacterial spondylitis -- Tuberculous spondylitis -- Epidural abscess -- Granulomatous inflammations of the spinal cord -- Arachnoiditis -- Acute transverse myelitis -- Spinal Multiple sclerosis --; 5. Tumors -- Hemangioma -- Osteoid osteoma -- Osteoblastoma -- Osteochondroma -- Aneurysmal bone cyst -- Giant cell tumor -- Langerhans cell histiocytosis -- Malignant tumors -- Bone metastases -- Multiple myeloma -- Chordoma -- Ewing sarcoma -- Lymphoma -- Nerve sheath tumors -- Leptomeningeal and intramedullary metastases -- Meningioma -- Ependymoma -- Astrocytoma -- Hemangioblastoma -- 6. Vascular disorders -- Epidural hematoma -- Arteriovenous malformation -- Arterial spinal cord infarction -- 7. Postoperative disorders -- Failed back surgery syndrome -- CSF fistula -- Peridural fibrosis -- Rapidly progressive osteoarthritis (after intersegmental fusion) -- Complications of spinal instrumentation -- 8. Metabolic disorders -- Senile and postmenopausal osteoporosis -- Paget disease -- Spinal epidural lipomatosis.
  • Sect. I. General considerations. 1. History of spine injections / Sheryl L. Johnson and Kevin E. Vorenkamp -- 2. Therapeutic agents for spine injection: local anesthetics, steroids, and contrast media / Matthew J. Pingree and Marc A. Huntoon -- 3. Fluoroscopy, ultrasonography, computed tomography, and radiation safety / Stanley Golovac -- Sect. II. Peripheral nerve blocks. 4. Differential diagnostic nerve blocks / Jerald Garcia, I. Elias Veizi, and Salim M. Hayek -- 5. Head and neck blocks / Samer Narouze -- 6. Upper extremity peripheral nerve blockade / Hugh M. Smith and Christopher M. Duncan -- 7. Lower limb blacks / Padraig Mahon and Colin J.L. McCartney -- 8. Cervical and lumbar sympathetic blocks / Samer Narouze and Sean Graham -- 9. Nerve destruction for the alleviation of visceral pain / Kacey A. Montgomery and Robert W. Hurley -- 10. Peripheral applications of ultrasonography for chronic pain / Philip Peng -- Sect. III. Injections for back pain. 11. Therapeutic epidural injections: interlaminar and transoraminal / Marc A. Huntoon and Abram H. Burgher -- 12. Facet (zygapophyseal) intraarticular joint injections: cervical, lumbar, and thoracic / Jason E. Pope and Jianguo Cheng -- 13. Medial branch blocks: cervical, thoracic, and lumbar / Seth A. Waldman, Vinita Parikh, and Dawood Sayed -- 14. Radiofrequency rizotomy for facet syndrome / Jan van Zundert ... [et al.] -- 15. Sacroiliac joint injections and lateral branch blocks, including water-cooled neurotomy / Bryan S. Williams -- 16. Pulsed radiofrequency / Khalid Malik and Honorio T. Benzon -- 17. Discogenic pain and discography for spinal injections / Stanley Golovac -- 18. Minimally invasive intradiscal procedures for the treatment of discogenic lower back and leg pain / Leonardo Kapural and Dawn A. Sparks -- 19. Vertebral augmentation / Tristan C. Pico, Basem Hamid, and Allen W. Burton -- 20. Ultrasound-guided lumbar spine injections / Manfred Greher -- 21. Ultrasound-guided cervical spine injections / Samer Narouze -- 22. Musculoskeletal injections: iliopsoas, quadratus lumborum, piriformis, and trigger point injections / Anne Marie McKenzie-Brown, Kiran Chekka, and Honorio T. Benzon -- 23. Ultrasound-guided and fluoroscopically guided joint injections / Steve J. Wisniewski and Mark-Friedrich B. Hurdle.
  • Pathophysiology of spinal cord injury / B. Timothy Himes -- The neurological evaluation and medical management of acute spinal cord injury / Anthony S. Burns and Ralph J. Marino -- Surgical treatment of spinal injury / Daniel R. Fassett and James S. Harrop -- Controversies in clearing the spine / C. Craig Blackmore and Ken F. Linnau -- Plain film radiography and computed tomography of the cervical spine. Part I. Normal anatomy and spinal injury identification / Alejandro Zuluaga Santamaria and Diego B. Núñez, Jr. -- Plain film radiography and computed tomography of the cervical spine. Part II. Classification and subtypes of spinal injury / Alejandro Zuluaga Santamaria and Diego B. Núñez, Jr. -- Imaging of thoracolumbar spinal injury / George Koulouris, Amy Y.I. Ting, and William B. Morrison -- Magnetic resonance imaging of acute spinal trauma / Adam E. Flanders -- Imaging of pediatric spinal trauma / Avrum N. Pollock and Stephen M. Henesch -- Postoperative spinal imaging / Ashwini D. Sharan, Hana Choe, and Laura Snyder -- Imaging of the previously injured spinal cord / Steven Falcone -- Experimental therapies for spinal cord injury / Marion Murray -- Experimental techniques of spinal imaging / Eric D. Schwartz.
  • Offers information needed to maximize the potential of ultrasound in daily practice. Topics include nephrology, urology, the urogenital tract in the child, non-ultrasound imaging of the urogenital tract, oncological management of tumors of the urogenital tract, and more.
  • In the past decade, few issues at the intersection of medicine and sports have had as high a profile or have generated as much public interest as sports-related concussions. In recent years there has been a growing awareness and understanding that all concussions involve some level of injury to the brain and that athletes suspected of having a concussion should be removed from play for further evaluation (CDC, 2013; Halstead et al., 2010). Despite the increased attention, however, confusion and controversy persist in many areas, from how to define a concussion and how multiple concussions affect the vulnerability of athletes to future injury, to when it is safe for a player to return to sports and the effectiveness of protective devices and other interventions in reducing the incidence and severity of concussive injuries (Wilde et al., 2012). Parents worry about choosing sports that are safe for their children to play, about finding the equipment that can best protect their children, and about when, if a child does receive a concussion, it will be safe for him or her to return to play or if it might be time to quit a much-loved sport entirely. It is within this context that the Institute of Medicine (IOM) and National Research Council (NRC), in October 2012, convened the Committee on Sports-Related Concussions in Youth to review the science of sports-related concussions in youth from elementary school through young adulthood, including military personnel and their dependents, and to prepare a report on that topic based on that review. The committee was charged with reviewing the available literature on concussions within the context of developmental neurobiology, specifically relating to the causes of concussions, their relationship to impacts to the head or body during sports, the effectiveness of protective devices and equipment, screening for and diagnosis of concussions, their treatment and management, and their long-term consequences.
  • "The massive amount of nonstandard high-dimensional brain imaging data being generated is often difficult to analyze using current techniques. This challenge in brain image analysis requires new computational approaches and solutions. But none of the research papers or books in the field describe the quantitative techniques with detailed illustrations of actual imaging data and computer codes. Using MATLABʼ and case study data sets, Statistical and Computational Methods in Brain Image Analysis is the first book to explicitly explain how to perform statistical analysis on brain imaging data. The book focuses on methodological issues in analyzing structural brain imaging modalities such as MRI and DTI. Real imaging applications and examples elucidate the concepts and methods. In addition, most of the brain imaging data sets and MATLAB codes are available on the author's website. By supplying the data and codes, this book enables researchers to start their statistical analyses immediately. Also suitable for graduate students, it provides an understanding of the various statistical and computational methodologies used in the field as well as important and technically challenging topics."--Provided by publisher.
  • History of status epilepticus / Peter W. Kaplan -- Types of status epilepticus: definitions and classification / Frank W. Drislane -- Differential diagnosis of status epilepticus; pseudostatus epilepticus / Barbara A. Dworetzky, Edward B. Bromfield -- The epidemiology of status epilepticus / Elizabeth J. Waterhouse -- The electroencephalogram in status epilepticus / Susan T. Herman -- Generalized convulsive status epilepticus: causes, systemic manifestations, and consequences / Bernard S. Chang -- Focal status epilepticus / Donald L. Schomer -- The Cellular physiology of status epilepticus / Omotola Hope, Hal Blumenfeld -- Cellular damage and the neuropathology of status epilepticus / Nathan B. Fountain -- Clinical presentations of nonconvulsive status epilepticus / Peter W. Kaplan -- Cognitive manifestations of status epilepticus: ictal aphasia, amnesia, and psychosis / Michael Benatar -- Nonconvulsive status epilepticus: morbidity and consequences / Frank W. Drislane -- Treatment of generalized convulsive status epilepticus / Tina Shih, Carl W. Bazil -- Treatment of refractory status epilepticus / Teresa L. Smith, Thomas P. Bleck -- Treatment of nonconvulsive status epilepticus / Frank W. Drislane -- Status epilepticus in children / James J. Riviello, Jr. -- Status epilepticus in neonates / John N. Gaitanis, James J. Riviello, Jr.
  • "This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control"--Publisher's description.
  • Technology for peripheral nerve stimulation / Parker, J.L., Cameron, T. -- Theoretical basis of vagal nerve stimulation / Attenello, F., Amar, A.P., Liu, C., Apuzzo, M.L.J. -- Vagal nerve stimulation : surgical technique and complications / Tronnier, V.M. -- Vagus nerve stimulation for epilepsy : an evidence-based approach / Cukiert, A. -- Vagus nerve stimulation for major depressive episodes / Eljamel, S. -- Phrenic nerve stimulation : technology and clinical applications / Abdunnur, S.V., Kim, D.H. -- Trigeminal ganglion stimulation / Van Buyten, J.-P. -- Carotid sinus/nerve stimulation for treatment of resistant hypertension and heart failure / Yin, D., Slavin, K.V. -- Hypoglossal nerve stimulation for obstructive sleep apnea / Mwenge, G.B., Rombaux, P., Lengele, B., Rodenstein, D. -- Sphenopalatine ganglion stimulation in neurovascular headaches / Schoenen, J. -- Occipital stimulation for migraine : update from recent multicenter trials -- Schwedt, T.J., Green, A.L., Dodick, D.W. -- Peripheral nerve stimulation for back pain / Verrills, P., Russo, M. -- Peripheral nerve stimulation for pain in extremities : an update / Pope, J.E., Carlson, J.D., Rosenberg, W.S., Slavin, K.V., Deer, T.R. -- Peripheral neuromodulation to treat postamputation pain / Soin, A., Fang, Z.-P., Velasco, J. -- Peripheral neurostimulation with a microsize wireless stimulator / Yearwood, T.L., Perryman, L.T. -- Sacral neuromodulation for genitourinary problems / Banakhar, M., Hassouna, M. -- Sacral nerve stimulation in the treatment of bowel disorders / Nordenstam, J., Boller, A.-M., Mellgren, A. -- Stimulation of the dorsal root / Ganglion Liem, L. -- Regulation of peripheral nerve stimulation technology / Birk, D.M., Yin, D., Slavin, K.V.
  • Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authors concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation.
  • Stroke book. 2nd ed. 2013
    Section I. Assessment of Stroke Patients -- 1. Emergency medical services (EMS): first line of defense against stroke -- 2. Initial assessment of patients with stroke-like symptoms -- 3. Clinical stroke syndromes and localization -- Section II. The Hunt for a Stroke Etiology -- 4. The Hunt for a stroke etiology: ischemic stroke -- 5. The Hunt for a stroke etiology: hemorrhagic stroke -- 6. Uncommon causes of stroke and stroke mimics -- Section III. Acute Stroke Imaging -- 7. Computed tomography in acute stroke -- 8. Magnetic resonance imaging in acute stroke -- 9. Neurosonology in acute ischemic stroke -- Section IV. Management of Stroke Patients -- 10. Ischemic stroke in the first 24 hours -- 11. Management of the acute ischemic stroke patient beyond 24 hours -- 12. Intracerebral hemorrhage -- 13. Subarachnoid hemorrhage and its medical management -- 14. Dural and cerebral venous thrombosis -- Section V. Stroke in Consultation -- 15. Perioperative stroke -- 16. Stroke on OB/Gyn wards -- 17. Stroke on pediatric wards -- Section VI. Prevention of First and Recurrent Stroke -- 18. Antithrombotic therapies -- 19. Surgical and endovascular therapies -- 20. Stroke risk factors: impact and management -- 21. Synopsis of landmark studies in ischemic stroke.
  • Stroke genetics 2013
    Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Â Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
  • Introduction to stroke genomics / Simon J. Read and Frank C. Barone -- Choice, methodology, and characterization of focal ischemic stroke models: the search for clinical relevance / David Virley -- Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat / Hilary V. O. Carswell ... [et al.] -- Gene therapy in neurological disease / Midori A. Yenari and Robert M. Sapolsky -- Stem cell transplantation after middle cerebral artery occlusion / Paul Stroemer and Helen Hodges -- Endogenous brain protection: models, gene expression, and mechanisms / Frank C. Barone -- Production of transgenic and mutant mouse models / Alex Harper -- 3-nitropropionic acid model of metabolic stress: assessment by magnetic resonance imaging / Toby John Roberts -- Practicalities of genetic studies in human stroke / Ahamad Hassan and Hugh S. Markus -- Evaluation of the interactions of common genetic mutations in stroke / Zoltán Szolnoki -- Technologies of disease-related gene discovery using preclinical models of stroke / Xinkang Wang -- Quantitative analysis of gene transcription in stroke models using real-time RT-PCR / David C. Harrison and Brian C. Bond -- Effective analysis of genomic data / Paul R. Nelson, Andrew B. Goulter, and Richard J. Davis -- Bioinformatic approaches to assigning protein function from novel sequence data / David Michalovich and Richard Fagan -- Pragmatic target discovery from novel gene to functionally defined drug target: the interleukin-1 story / Stuart McRae Allen.
  • Stroke in children and young adults : overview, risk factors and prognosis / Betsy B. Love, José Biller -- Applied anatomy of the brain arteries / William DeMyer -- Stroke in neonates and children : overview / Meredith R. Golomb -- Diagnostic strategies in neonates, children, and young adults with stroke / Deborah K. Sokol, Hema Patel -- Atherosclerotic cerebral infarction in young adults / José Biller, Rima M. Dafer -- Non-atherosclerotic cerebral vasculopathies / Rima M. Dafer, José Biller -- Cardiac disorders and stroke in children and young adults / José Biller, Michael J. Schneck, Betsy B. Love -- Cerebral infarction and migraine / Rima M. Dafer, José Biller. Hemostatic disorders presenting as cerebral infarction / Rima M. Dafer, José Biller -- Stroke and pregnancy / Rima M. Dafer, José Biller -- Rare genetic disorders predisposing to stroke / Betsy B. Love, James F. Meschia, José Biller -- Cerebral venous thrombosis / Rima M. Dafer, José Biller -- Neonatal intracranial hemorrhage / Eugene R. Schnitzler, Marc G. Weiss -- Spontaneous intracerebral hemorrhage / José Biller, Michael Schneck -- Subarachnoid hemorrhage in young adults / Lotfi Hacein-Bey, Thomas C. Origitano, José Biller -- Pediatric CNS vascular malformations / Thomas J. Altstadt, Mitesh V. Shah -- Vascular disorders of the spinal cord in children and young adults / Richard B. Rodgers, Michael B. Pritz.
  • Stroke management and recovery / Bruce Ovbiagele -- Stroke pathophysiology / Sarkis Morales-Vidal & José Biller -- Risk factors and primary prevention / Rita V. Krishnamurthi, Kelly M. Jones & Valery L. Feigin -- Early symptoms, signs and diagnosis of stroke / Sweta Adatia & Andrew Demchuk -- Hyperacute stroke management / Edward Jauch, Christine Holmstedt & Mark McCaslin -- In-hospital management of stroke / Michel Shamy, Karl Meisel & S. Andrew Josephson -- Medications for recurrent stroke prevention / Muhammad U. Farooq & Philip B. Gorelick -- Surgical prevention of stroke / Andrew R. Barleben, Wesley S. Moore & Thomas G. Brott -- Stroke prevention : diet and lifestyle / Jorge Pagola & Carlos A. Molina -- Multidisciplinary stroke rehabilitation and prognosis / Robert W. Teasell & Ricardo Viana -- Physical and occupational therapy / Richard D. Zorowitz -- Speech and language therapy / Marlís González-Fernández & Argye E. Hillis -- Management of postdischarge complications / Bernadette N. Borte & Enrique C. Leira -- Stroke systems of care / Alec Fraser, Charles Wolfe, Anthony Rudd & Christopher McKevitt -- Index.
  • Safety and efficacy of transplanting immortalized neural stem cells in stroke patients -- Transplantation of bone marrow stromal cells for the treatment of stroke -- Cord blood cells as a treatment for stroke -- Adipose-derived stem cells as a potential therapy for stroke -- Novel imaging modalities to monitor implanted embryonic stem cells in stroke -- Cell transplantation for intracerebral hemorrhage -- Therapeutic strategies employing endogenous neural stem cells in tissue remodeling following ischemic injury: the promise, the peril and novel future applications -- Ethics and stem cell research -- Special conditions in the design of clinical stroke trials for cell transplantation.
  • Vascular biology and athersclerosis of cerebral vessels / Sophocles Chrissobolis, Christopher G. Sobey -- Mechanisms of Thrombosis and thrombolysis / Gregory J. del Zoppo -- Cerebral blood flow and metabolism : regulation and pathophysiology in cerebrovascular disease / William J. Powers -- Histopathology of brain tissue response to stroke and injury / Roland N. Auer -- Molecular and cellular mechanisms of ischemia-induced neuronal death / Haiyue Zhang [and 6 others] -- Intracellular signaling : mediators and protective responses / John W. Thompson [and 3 others] -- The neurovascular unit and responses to ischemia / Gregory J. del Zoppo, Michael Moskowitz, Maiken Nedergaard -- Mechanisms of cerebral hemorrhage / Jaroslaw Aronowski [and 3 others] -- White matter pathophysiology / Bruce R. Ransom [and 3 others] -- Inflammation and immune response / Josef Anrather, Costantino Iadecola, John Hallenbeck -- Mechanisms of plasticity, remodeling and recovery / Zheng Gang Zhang, Michael Chopp -- Genetics and vascular biology of angiogenesis and vascular malformations / Helen Kim [and 3 others] -- Global burden of stroke / Valery L. Feigin, Rita V. Krishnamurthi -- Stroke disparities / George Howard, Virginia J. Howard -- Modifiable risk factors and determinants of stroke / Sudha Seshadri, Philip A. Wolf -- Prognosis after stroke / Tatjana Rundek, Ralph L. Sacco -- Vascular dementia and cognitive impairment / Sudha Seshadri, Alexis Economos, Clinton Wright -- Genetic basis of stroke occurrence, prevention and outcome / James F. Meschia, Daniel Woo, David Werring -- Preventing a first stroke / Larry B. Goldstein, Ralph L. Sacco -- Classification of ischemic stroke / Hakan Ay --Clinical scales to assess patients with stroke / Harold P. Adams, Jr. -- Carotid artery disease / Leo H. Bonati, Martin M. Brown -- Anterior cerebral artery disease / John C.M. Brust, Angel Chamorro -- Middle cerebral artery disease / Vijay K. Sharma, Lawrence K.S. Wong -- Posterior cerebral artery disease / Jong S. Kim -- Vertebrobasilar disease / Jong S. Kim, Louis R. Caplan -- Lcunar syndromes, lacunar infarcts, and cerebral small-vessel disease / Bo Norrving -- Intracerebral hemorrhage / Carlos S. Kase [and 3 others] -- Aneurysmal subarachnoid hemorrhage / José I. Suarez, Eric M. Bershad -- Arteriovenous malformations and other vascular anomalies / Christian Stapf -- Stroke and other vascular syndromes of the spinal cord / Joshua Z. Willey -- Cardiac diseases / David M. Greer, Shunichi Homma, Karen L. Furie -- Atherosclerotic disease of the proximal aorta / Marco R. Di Tullio, Shunichi Homma -- Stroke related to surgery and other procedures / Steven R. Messé, Michael T. Mullen -- Arterial dissections and fibromuscular dysplasia / Richard M. Zweifler, Gerald Silverboard -- Collagen vascular and infectious diseases / Jose Gutierrez, Mira Katan, Mitchell S.V. Elkind -- Reversible cerebral vasoconstriction syndromes / Aneesh B. Singhal -- Hypertensive encephalopathy / Catherine Lamy, Jean-Louis Mas -- Stroke and substance abuse / John C.M. Brust -- Moyamoya disease / Masahiro Yasaka, Takenori Yamaguchi, Jun Ogata -- CADASIL : cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy / Hugues Chabriat [and 3 others] -- Hematologic disorders and stroke / Cheryl Bushnell -- Migraine and stroke / Hans Christoph Diener, Tobias Kurth -- Cryptogenic stroke / Martin O'Donnell, Scott E. Kasner -- Cerebral venous thrombosis / José M. Ferro, Patrícia Canhão -- Ultrasonography / Michal Haršány, Georgios Tsivgoulis, Andrei V. Alexandrov -- Computed tomography-based evaluation of cerebrovascular disease / Imanuel Dzialowski [and 3 others] -- Magnetic resonance imaging of cerebrovascular diseases / Maarten G. Lansberg [and 4 others] -- Cerebral angiography / Ronald J. Sattenberg [and 4 others] -- Prehospital and emergency department care of the patient with acute stroke / Anna Gensic, Arthur Pancioli -- Intravenous thrombolysis / Wendy Brown, Patrick D. Lyden -- Antithrombotic therapy for treatment of acute ischemic stroke / Harold P. Adams Jr., Patricia H. Davis -- General stroke management and stroke units / Turgut Tatlisumak, Risto O. Roine -- Critical care of the patient with acute stroke / Marek Sykora, Silvia Schönenberger, Julian Bösel -- Pharmacologic modification of acute cerebral ischemia / Nicole R. Gonzales, James C. Grotta -- Treatment of "other" stroke etiologies / Scott E. Kasner, Brett L. Cucchiara -- Medical therapy of intracerebral and intraventricular hemorrhage / Darin B. Zahuranec, Lewis B. Morgenstern -- Rehabilitation and recovery of the patient with stroke / Bruce H. Dobkin -- Interventions to improve recovery after stroke / Steven C. Cramer -- Enhancing stroke recovery with cellular therapies / Sean I. Savitz, Kaushik Parsha -- Antiplatelet therapy for secondary prevention of stroke / Thalia S. Field [and 3 others] -- Secondary prevention of cardioembolic stroke / Karen Furie, Muhib Khan -- Conduct of stroke-related clinical trials / Adriana Pérez, Barbara C. Tilley -- Endovascular therapy of extracranial and intracranial occlusive disease / Maxim Mokin, Elad I. Levy -- Endovascular treatment of acute ischemic stroke / Reza Jahan, Jeffrey L. Saver -- Endovascular treatment of cerebral aneurysms / Ajay K. Wakhloo [and 3 others] -- Interventional therapy of brain and spinal arteriovenous malformations / Timo Krings, Sasikhan Geibprasert, Karel Ter Brugge -- Dural arteriovenous malformations / Javed Khader Eliyas, Issam A. Awad -- Surgery of anterior and posterior aneurysms / Mark J. Dannenbaum [and 4 others] -- Surgery for intracerebral hemorrhage / A. David Mendelow, Barbara A. Gregson --Intraventricular hemorrhage / J. Max Findlay -- Surgical management of cranial and spinal arteriovenous malformations / Jonathan Russin, Robert F. Spetzler -- Surgical cavernous malformations and venous anomalies / Najib E. El Tecle [and 7 others] -- Indications for carotid endarterectomy in patients with asymptomatic and symptomatic carotid stenosis / John A. Braca III [and 3 others] -- Extracranial to intracranial bypass for cerebral ischemia / David W. Newell, Marcelo D. Vilela, William J. Powers -- Decompressive craniectomy for infarction and hemorrhage / Hermann Neugebauer [and 3 others]
  • Part I. Structure and ligands of NCAM. -- Structural biology of NCAM / Vladislav Soroka, Christina Kasper, Flemming M. Poulsen. -- Extracellular protein interactions mediated by the neural cell adhesion molecule, NCAM: heterophilic interactions between NCAM and cell adhesion molecules, extracellular matrix proteins, and viruses / Janne Nielsen, Nikolaj Kulahin, Peter S. Walmod. -- Intracellular (intracelluar) ligands of NCAM / Bettina Buttner, Rudiger horstkorte. -- Role of ATP in the regulation of NCAM function / Martin V. Hubschmann, Galina Skladchikova. -- Part II. NCAM and plysialic acid. -- Polysialylation of NCAM / Herbert Hildebrandt, Martina Muhlenhoff, Rita Gerardy-Schahn. -- Structural basis for the polysialylation of the neural cell adhesion molecule / Karen J. Colley. -- Role of PSA-NCAM in adult neurogenesis / Eduardo Gascon, Laszlo Vutskits, Jozsel Zoltan Kiss. -- Use of PSA-NCAM in repair of the central nervous system / Abderrahman El Maarouf, Urs Rutishauser. -- Part III. NCAM-mediated signal transduction. -- Signaling pathways involved in NCAM-induced neurite outgrowth / Dorte Kornerup Ditlevsen, Kateryna Kolkova. -- Role of the growth-associated protein GAP-43 in NCAM mediated neurite outgrowth / Irina Korshunova, Mark Mosevitski. -- Neural cell adhesion molecule NCAM and lipid rafts / Gro Klitgaard Povlsen, Dorte Kornerup Ditlevsen. -- Neural cell adhesion molecule and epidermal growth factor receptor: signaling crosstalk / Gro Klitgaard Polvsen. -- Part IV. NCAM metabolism. -- Biosynthesis of NCAM / Kateryna Kolkova. -- Soluble NCAM / Thomas Secher. -- Part V. NCAM, synapses, emotions, and memory. -- Role of NCAM in spine dynamics and synaptogenesis / D. Muller, P. Mendez, M. DeRoo, P. Klauser, S. Steen, and L. Poglia. -- NCAM in long-term potentiation and learning / Barbara P. Hartz, Lars Christian B. Roon. -- Role of NCAM in emotion and learning / Lisa Conboy, Reto Bisaz, Kamila Markram, Carment Sandi. -- Part VI. NCAM in disease. -- NCAM in neuropsychiatric and neurodegenerative disorders / Leann H. Brennaman, Patricia F. Maness. -- Neural cell adhesion molecule in cancer: expression and mechanisms / Silvia Zecchini, Ugo Caallaro. -- Part VII. Pharmacology of NCAM: NCAM mimetics. -- NCAM mimetic peptides: an update / Vladimir Berezin, Elisabeth Bock. -- Synthetic NCAM-derived ligands of the fibroblast growth factor receptor / Stine maria Hansen, Shizhong Li, Elisabeth Bock, Vladimir Berezin. -- Dendritic spine and synapse morphological alterations induced by neural cell adhesion molecule mimetic / Michael Stewart, Victor Popov, Nikolai Medvedev, Paul Giabbon, Nicola Corbett, Igor Kraev, Heather Davies. -- Part VIII. Orthologs and paralogs of NCAM. -- Fasciclin II: the NCAM ortholog in Drosophila melanogaster / Lars V. Kristiansen, Michael Hortsch. -- Neural cell adhesion molecule NCAM2/OCAM/RNCAM, a close relative to NCAM / Nikolaj Kulahin, Peter S. Walmod. -- Part IX. Conclusion. -- Honoring Dr. Elisabeth Bock / Vladimir Berezin.
  • This volume systematically reviews the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as oxidative stress, in the pathology of Alzheimer's disease. It describes the most current diagnostic tools, laboratory methods and technology, and suggests ways of prevention and treatment to emphasize the concept of the bench-to-bedside approach. Studies on Alzheimer's Disease provides thorough coverage of emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents, and several more relevant aspects. In addition, this book promotes the concept of using biomarkers representative of oxidative stress reactions and free-radical damage, as well as describing the effects of antioxidants in treating disease in clinical trials. This content is invaluable to both researchers studying the development of and clinicians treating patients with a diagnosis of Alzheimer's Disease.
  • "This pocket-sized book is a quick-reference practical guide for physicians who deal with patients with subarachnoid hemorrhage or intracranial aneurysms outside the hospital. It describes briefly the epidemiology of subarachnoid hemorrhage, the early recognition and clinical course, and in more depth the aftercare, residual symptoms and deficits. The prognosis and management in the long term are discussed in detail. It also provides information on the counselling and treatment of patients with unruptured intracranial aneurysms. Subarachnoid Hemorrhage in Clinical Practice is aimed at general practitioners and family physicians and will also be informative for other specialists such as rehabilitation physicians, nursing home physicians, and physicians working for health insurance companies. It may also be of interest to patients, relatives, and paramedics."--Back cover.
  • Defines the functional neuroanatomy of cortical-subcortical circuitries and establishes that since structure is related to function, what the basal ganglia and cerebellum do for movement they also do for cognition and emotion. This book also examines neuropsychological assessment.
  • Introduction -- Cytology of the subthalamic nucleus -- Ontogeny of the subthalamic nucleus -- Topography of the rat, cat, baboon, and human subthalamic nucleus -- Connections of the subthalamic nucleus -- Nigro-subthalamic connections in rat.
  • Sudden infant death syndrome (SIDS) is characterised by the sudden death of an infant that is not predicted by prior medical history and it is still responsible for a large percentage of infant mortalities. The exact causes have long remained unknown, though some risk factors such as including exposure to tobacco smoke, no breast feeding, and prone sleeping position, have been identified. However an analysis linking neurophysiological and neuropathological aspects in a prospective study of SIDS suggests that one of the causes of SIDS is arousal deficiency. This unique book provides the latest, comprehensive information on SIDS research from epidemiology to physiology.
  • Sleep Disordered Breathing / Kerstin Rohde and Thomas Verse -- General Aspects of Therapy / Thomas Verse -- Identifying the Site of Obstruction / Joachim T. Maurer and Thomas Verse -- Nasal Surgery / Thomas Verse and Wolfgang Pirsig -- Nasopharyngeal Surgery / Thomas Verse and Wolfgang Pirsig -- Palatal Surgery / Thomas Verse, Wolfgang Pirsig and Joachim T. Maurer -- Lower Pharyngeal Airway Procedures / Boris A. Stuck, Thomas Verse, Nico de Vries and Joachim T. Maurer -- Maxillofacial Surgeries / Thomas Verse and Thomas Hierl -- Laryngeal OSA / Thomas Verse -- Multilevel Surgery / Thomas Verse -- Tracheotomy / Thomas Verse and Wolfgang Pirsig -- Bariatric Surgery / Helge Kleinhans and Thomas Verse -- Anesthesiologic Airway Management / Harald V. Genzwuerker.
  • Section I: Brachial plexus injury and entrapments -- Brachial plexus avulsion--diagnostic issues / Thomas Kretschmer and Robert L. Tiel -- Upper brachial plexus injury (duchenne-erb palsy) / Andrew C. Kam and Daniel H. Kim -- Lower trunk brachial plexus palsy / Lynda J-S. Yang and John E. McGillicuddy -- Gunshot wounds to the brachial plexus / Robert J. Spinner and Robert L. Tiel -- Lateral cord injury / Robert L. Tiel and Eric L. Zager -- Medial cord injury / Robert J. Spinner and Robert L. Tiel -- Pediatric plexus injuries / James M. Drake, Patrick A. Lo, and Rajiv Midha -- Secondary reconstruction in obstetric brachial plexus injuries / Rahul K. Nath ... [et al.] -- Free functioning muscle transfers for upper extremity reconstruction of plexus palsy / Dimitri J. Anastakis and Ralph T. Manktelow -- Dorsal root entry zone: lesioning for intractable deafferentation pain / Mahmood Fazl ... [et al.] -- Neurotization in brachial plexus injury / Rahul K. Nath ... [et al.] -- Thoracic outlet syndrome / Eric L. Zager -- Nerve transfers for shoulder reanimation / Bassam M. J. Addas and Rajiv Midha -- Fascicular nerve transfers to restore elbow flexion / Ronald T. Grondin, S. Durand, and Christophe Oberlin -- Section II: Upper extremity peripheral nerve injuries and entrapments -- Spinal accessory nerve palsy / Robert L. Tiel and Eric L. Zager -- Long thoracic nerve palsy / Adrian W. Laxton and Rajiv Midha -- Suprascapular nerve palsy / Adrian W. Laxton and Rajiv Midha -- Axillary nerve injury and repair / Deb Bhowmick and Eric L. Zager -- Injury to the median nerve above the elbow / Ben Roitberg -- Anterior interosseous nerve syndrome/compression / Allen H. Maniker -- Carpal tunnel syndrome / Sheila K. Singh and Rajiv Midha -- Endoscopic carpal tunnel release / David F. Jimenez and Thomas Loftus -- Recurrent or persistent symptoms following carpal tunnel release / Brent Graham -- Digital nerve injuries / Paul Binhammer -- Ulnar nerve injury / Marie-Noëlle Hébert-Blouin and Line Jacques -- Failed ulnar nerve transposition due to unrecognized snapping of the medial triceps / Robert J. Spinner and Rajiv Midha -- Ulnar nerve entrapment at the elbow / Farhad Pirouzmand and Rajiv Midha -- Ulnar nerve compression--guyon canal / Christopher Doumas and David R. Steinberg -- Failed ulnar nerve decompression / James B. Lowe III and Susan E. Mackinnon -- Management of penetrating (lacerating) nerve injuries / Mandeep S. Tamber and Rajiv Midha -- Radial nerve injury: midhumeral level / Mubarak Al-Gahtany and Rajiv Midha -- Radial tunnel syndrome / Farhad Pirouzmand and Rajiv Midha -- Posterior interosseous nerve injury / Andrew Nataraj and Rajiv Midha -- Nerve repair with conduits / Matthew Sanborn, Eric M. Jackson, and Eric L. Zager -- Section III: Lower extremity peripheral nerve injuries and entrapments -- Ilioinguinal/iliohypogastric neuropathy / R. Graham Vanderlinden and Rajiv Midha -- Meralgia paresthetica / Douglas Cook and Rajiv Midha -- Obturator nerve injury and repair / Jason H. Huang, Robert G. Whitmore, and Eric L. Zager -- Femoral neuropathy by compression from iliacus compartment hematoma / Farhad Pirouzmand and Rajiv Midha -- Femoral nerve injuries / Allen H. Maniker -- Saphenous nerve lesions / Robert J. Spinner and Robert L. Tiel -- Sciatic nerve compression and piriformis syndrome / Robert J. Spinner and Robert L. Tiel -- Sciatic nerve injury and repair / Robert G. Whitmore, Deb Bhowmick, and Eric L. Zager -- Diagnosis and treatment of common peroneal nerve problems / Tarvinder Singh and Michel Kliot -- Peroneal nerve entrapment / Kimberly Harbaugh and Rajiv Midha -- Sural nerve injury and neuroma / Rajiv Midha -- Posterior tibial nerve injury / Justin L. Owen ... [et al.] -- Tarsal tunnel syndrome / Robert J. Spinner and Robert L. Tiel -- Morton neuroma / Neal J. Naff -- Section IV: Nerve tumors, painful nerve conditions, and miscellaneous injuries -- Schwannoma / W. Bradley Jacobs and Rajiv Midha -- Neurofibroma / W. Bradley Jacobs and Rajiv Midha -- Management of malignant peripheral nerve sheath tumors / Nabeel Al-Shafai, Rajiv Midha, and Abhijit Guha -- Brachial plexus tumor / Mubarak Al-Gahtany and Rajiv Midha -- Neurogenic sarcoma of the sciatic nerve / Charles Christian Matouk and Rajiv Miidha -- Lumbar plexus injury / Eric M. Jackson and Eric L. Zager -- Complex regional pain syndrome / Raqeeb Haque and Christopher J. Winfree -- Upper dorsal sympathectomy for hyperhidrosis / Mahmood Fazl -- Electrical stimulation for painful neuroma / Michael J. Dorsi and Allan J. Belzberg.
  • Featuring an expanded focus on in-demand endoscopic and minimally invasive spine procedures, Surgical Anatomy and Techniques to the Spine, 2nd Edition pairs new anatomic photographs and radiographic images with expertly rendered color illustrations and clear, step-by-step descriptions to help you effectively perform all of the latest and most effective spine surgery techniques. A multidisciplinary approach makes this medical reference book relevant and informative to all surgeons regardless of their specialty or level of surgical experience with the spine. Proceed with confidence. An atlas-style format featuring clear, concise, step-by-step descriptions of the anatomy and procedures along with clinical hints and pearls, tables, and management algorithms provideing swift answers and trusted guidance.Sharpen your surgical acumen with a deeper understanding of the anatomy of the surgical target and related anatomy. Comprehensive information on cervical, cervical/thoracic, thoracic/lumbar, lumbar spine, lumbar/pelvis, and other surgical locations ensures the best approaches to spine surgery and results.Understand the spine from all angles with multiple-viewpoint, full-color photographs, and illustrations.
  • "Swaiman's Pediatric Neurology, by Drs. Kenneth Swaiman, Stephen Ashwal, Donna Ferriero, and Nina Schor, is a trusted resource in clinical pediatric neurology with comprehensive, authoritative, and clearly-written guidance. Extensively updated to reflect advancements in the field, this fifth edition covers new imaging modalities such as pediatric neuroimaging, spinal fluid examination, neurophysiology, as well as the treatment and management of epilepsy, ADHD, infections of the nervous system, and more. The fully searchable text is now available online at, along with downloadable images and procedural videos demonstrating intraventricular hemorrhage and white matter injury, making this an indispensable multimedia resource in pediatric neurology."--Publisher's website.
  • Part 1. Molecular organization of the pre- and postsynaptic scaffold -- Glutamate Receptors in Synaptic Assembly and Plasticity: Case Studies on Fly NMJs -- Scaffold Proteins at the Postsynaptic Density -- Diversity of Metabotropic Glutamate Receptor-Interacting Proteins and Pathophysiological Functions -- Regulation of the Actin Cytoskeleton in Dendritic Spines -- Synaptic Cell Adhesion Molecules -- Part 2. Molecular dynamics of the synapse -- Molecular Dynamics of the Excitatory Synapse -- The Brain's Extracellular Matrix and Its Role in Synaptic Plasticity -- Molecular Motors in Cargo Trafficking and Synapse Assembly -- Surface Traffic in Synaptic Membranes -- Synaptic Protein Degradation in Memory Reorganization -- AMPA Receptor Assembly: Atomic Determinants and Built-In Modulators -- Developmental Plasticity of the Dendritic Compartment: Focus on the Cytoskeleton -- Dendritic mRNA Targeting and Translation -- Gliotransmission and the Tripartite Synapse -- Part 3. Synapse-to-nucleus communication -- Roles of Neuronal Activity-Induced Gene Products in Hebbian and Homeostatic Synaptic Plasticity, Tagging, and Capture -- Long-Distance Signaling from Synapse to Nucleus via Protein Messengers -- Nuclear Calcium Signaling -- Integrating Neurotransmission in Striatal Medium Spiny Neurons -- Part 4.; Synaptic dysfunction and Synaptopathies -- Synaptic Dysfunction and Intellectual Disability -- Synaptic Pathology of Down Syndrome -- The Synaptic Pathology of Drug Addiction -- Synaptic Dysfunction in Schizophrenia -- Molecular and Cellular Aspects of Mental Retardation in the Fragile X Syndrome: From Gene Mutation/s to Spine Dysmorphogenesis -- Synaptic Dysfunction in Parkinson's Disease -- Synaptic Dysfunction in Alzheimer's Disease.
  • Syringomelia is a relatively rare clinical entity in which fluid-filled cavities develop within the spinal cord. Although modern imaging technologies usually permit an accurate diagnosis at an early stage, syringomyelia remains an enigmatic condition that continues to fascinate neurosurgeons, neurologists and other specialists. This reference monograph provides an up-to-date account of the present stateofunderstanding of syringomyelia and related disorders.The editors aim to document the best clinical practice in diagnosis and treatment and to provide clear guidance on how to reduce the incidence of severe outcomes. New challenges are addressed, including the appropriate management of the increasing number of apparently idiopathic syrinx cavities that are detected. In addition, controversies in current practice and directions for future research are fully discussed. Syringomelia will be an invaluable source of information for experts in the field, specialists in various related disciplines and other interested health care professionals.
  • Part I. Brain-Machine Interfaces and Neurorehabilitation Brain-Computer Interfaces in the Rehabilitation of Stroke and Neurotrauma / Surjo R. Soekadar, Niels Birbaumer, and Leonardo G. Cohen -- Brain-Machine Interfaces for Persons with Disabilities / Kenji Kansaku -- Brain-Machine Interfaces Based on Computational Model / Yasuharu Koike, Hiroyuki Kambara, Natsue Yoshimura, and Duk Shin -- Improvement of Spastic Stroke Hemiparesis Using rTMS Combined with Motor Training / Satoko Koganemaru, Tatsuya Mima, Hidenao Fukuyama, and Kazuhisa Domen -- Molecular and Electrophysiological Approaches for Functional Recovery in Patients with Injured Spinal Cord / Toru Ogata, Noritaka Kawashima, Kimitaka Nakazawa, and Masami Akai -- Part II. Augmenting Cognition -- Prism Adaptation and the Rehabilitation of Spatial Neglect / Sophie Jacquin-Ciourtois, Jacinta O'Shea, Jacques Luauté, Laure Pisella, Alessandro Farné, Patrice Revol, Gilles Rode, and Yves Rossetti -- Toward a Cure Based on a Better Understanding of Autism Spectrum Disorder / Shigeru Kitazawa and Tamami Nakano -- Exceeding the Limits: Behavioral Enhancement Via External Influence / Katsumi Watanabe -- Neural Correlates of Reasoning by Exclusion / Akitoshi Ogawa.
  • "This reference covers clinical and bioengineering aspects of muscle reinnervation, a popular new technique at the boundary of biomedical and rehabilitation engineering and neuroscience. With contributions from pioneers in the field, the book provides a review of muscle reinnervation from a biomedical engineering and clinical perspective. It describes neuroscience and other related neuroprosthetic techniques. A companion website offers a wide range of videos and multimedia material to aid in comprehension and application"--Provided by publisher.
  • "Practical and clinically focused, Brain and Spine Imaging - a title in the Teaching Files Series - provides you with over 300 interesting and well-presented cases to help you better diagnose any disease of the brain and spine. Expert in the field, Dr. Girish Fatterpekar, MD uses a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for board exams. And, with Expert Consult functionality, you'll have convenient access to the full text online, all of the book's illustrations, additional cases and images, and links to PubMed at"--Publisher's website.
  • "Medical information is now widely available on the Internet and through telephone helplines such as NHS Direct and the focus on patient self care is likely to increase. Clinicians in all specialties will often encounter patients who have made self-directed searches for medical information prior to the clinical encounter. 'Teleneurology by Internet and Telephone' is a study of patient information-seeking behaviour in neurology patients prior to referral from primary to secondary care. The book analyses frequency of Internet access and use, and of telephone helpline awareness and use. It also explores use of these modalities over time, use according to patient gender and age and by gender and age over time. 'Teleneurology by Internet and Telephone' is an accessible overview of the utility of these modalities of health information provision and will be of interest not only to neurologists and clinicians in other specialities but also to public health researchers, sociologists and political scientists with an interest in questions of health care provision"--Provided by publisher.
  • Teleneurology in the United States Veteran Health Administration -- International Teleneurology -- Military Telemedicine -- Telemedicine Technology -- Telestroke -- Teleneurointensive Care Unit (TeleneurolICU) -- Teleneurology and Neurointerventional Therapy for Acute Stroke -- Teleneurosurgery -- Hospital Teleneurology -- Telemedicine and Parkinson Disease -- Telebeuropatholgy -- Tele-Epilepsy and Tele-Electroencephalography -- The Emerging Relevance of Telemedicine in Sleep Medicine -- Teledementia -- The Emerging Role of Telemedicine in the Evaluation of Sports-related Concussion -- Teleneurology in Contemporary Graduate Medical Education -- Legal Considerations in the Use of Telemedicine in Neurology -- Reimbursement in Teleneurology.
  • Introduction to the tethered cord syndrome / Shokei Yamada -- Normal spinal cord development and the embryogenesis of spinal cord tethering malformations / Mark S. Dias and Elias B. Rizk -- Pathophysiology of the tethered cord syndrome / Shokei Yamada ... [et al.] -- Neurologic assessment of tethered spinal cord / Sanford Schneider -- Imaging of tethered spinal cord / David B. Hinshaw ... [et al.] -- Ultrasonographic evaluation of tethered cord syndrome / Marvin D. Nelson Jr -- Urological aspect of tethered cord syndrome I : lower urinary tract dysfunction in tethered cord syndrome / H. Roger Hadley ... [et al.] -- Urological aspect of tethered cord syndrome II : clinical experience in urological involvement with tethered cord syndrome / Antoine E. Khoury -- The cervical tethered spinal cord / Kenji Muro, Arthur J. DiPatri Jr., and David G. McLone -- Indication and treatment of tethered spinal cord / James M. Drake and Harold J. Hoffman. Tethered cord syndrome associated with myelomeningoceles and lipomyelomeningoceles / Shokei Yamada ... [et al.] -- The role of folate supplementation in spina bifida occulta / Elias Rizk and Bermans J. Iskandar -- In utero repair of myelomeningoceles / Nalin Gupta -- Epidermoid and dermoid tumors associated with tethered cord syndrome / David S. Knierim, Daniel J. Won, and Shokei Yamada -- Tethered cord syndrome in adult and late-teenage patients without neural spinal dysraphism / Shokei Yamada ... [et al.] -- Tethered cord syndrome in adults with spina bifida occulta / Sharad Rajpal, Samir B. Lapsiwala, and Bermans J. Iskandar -- The normal position of the conus medullaris does not exclude a tethered spinal cord / R. Shane Tubbs and W. Jerry Oakes -- Anomalies of the spinal cord length and filum thickness / Shokei Yamada, Javed Siddiqi, and Shoko M. Yamada -- Intraoperative neurophysiological monitoring of the lower sacral nerve roots and spinal cord / Dachling Pang -- Clinical neurophysiology of tethered cord syndrome and other dysraphic syndromes / Robin L. Gilmore, Sun Ik Lee, and John Walsh -- Conservative versus surgical treatment and prognostic evaluation for tethered cord syndrome / Shokei Yamada ... [et al.].
  • Listening to an injured brain is not easy. It takes knowledge, dedication, and understanding of the critically ill patient and their family. It takes an appreciation of the logistics of care in these difficult times of imbalance between more and sicker patients and fewer medical specialists. The impact of the right personnel, whose interest and training is in neurocritical care, has shown promise, both in terms of improving patient outcome and quality. The editors have updated this second edition with the latest knowledge and trends. Gathering together a group of international experts who champions the three characteristics Patient and Family Centered High Quality Care, Education, and Discovery needed in our NeuroICUs, the editors present to the reader a comprehensive textbook of neurocritical care, incorporating best practice / evidence-based medicine and performance improvement. This book is not an effort to embellish the shelf of a medical library; it is a practical bedside friend to be used to improve the neurological outcomes of those for whom we are honored to care: our patients.
  • Textbook of Neuromodulation encompasses the basic principles, methods and current clinical applications of invasive and non-invasive neuromodulation. Neurophysiological systems are reviewed along with the basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. The overview of the neuromodulatory techniques is provided with special regard to safety and specific patient populations. Comprehensive and authored by leaders in the field, this resource presents the clinical potential, significance and practical applications of this innovative treatment approach.
  • Cervical spine anatomy -- Approaches to the upper cervical spine -- Anterior surgical approach to the cervical spine -- Posterior surgical approach to the cervical spine -- Anterior approaches and surgical considerations for pathology of the cervicothoracic junction -- Developmental and congenital disorders of the cervical spine -- Biomechanics of the cervical spine -- Evaluation of the cervical spine -- Radiographic and computed tomography evaluation of the cervical spine -- Magnetic resonance imaging of the cervical spine -- Neurophysiologic monitoring of the cervical spine -- Cervical degenerative disk disease -- Cervical radiculopathy -- Cervical spondylotic myelopathy -- Cervical deformity and treatment algorithms -- Ossification of the posterior longitudinal ligament -- Occipitocervical and upper cervical spine fractures -- Subaxial cervical spine injuries -- Spinal cord injuries and syndromes -- Traumatic arterial injuries : diagnosis and management -- Stingers and transient paresis -- Primary tumors of the spinal cord -- Primary bony tumors of the cervical spine -- Metastatic disease of the cervical spine -- Infections of the cervical spine -- Tuberculosis of the cervical spine -- Rheumatoid arthritis of the cervical spine -- Ankylosing spondylitis of the cervical spine -- Syringomyelia -- Anterior cervical diskectomy and fusion -- Anterior cervical corpectomy and fusion and hybrid techniques -- Cervical disk arthroplasty -- Anterior cervical foraminotomy -- Laminectomy and fusion -- Cervical laminoplasty -- Posterior cervical endoscopic laminoforaminotomy -- Osteotomies of the cervical spine -- Occipitocervical fixation -- C1 lateral mass and C2 pedicle screw fixation -- C1-C2 transarticular screws -- C2 translaminar screw fixation -- Cervical pedicle screws -- Lateral mass screws -- Interspinous wiring -- Minimally invasive techniques in the cervical spine -- Image-guided navigation for cervical spine surgery -- Biologics for intervertebral disk regeneration and repair -- Biologics for spinal fusion -- Intervertebral disk transplantation -- Vascular injuries -- Spinal cord and nerve injuries in the cervical spine -- Tracheoesophageal injuries -- Dural tear -- Wound complications -- Adjacent segment disease -- Nonunions and implant failures of the cervical spine.
  • As soldiers and combat veterans have returned from the wars in Iraq and Afghanistan traumatic brain injury (TBI) has been identified as the "signature injury" of those wars. TBI is also in the news on a daily basis due to sports injuries. This new edition has been revised and updated from the 2005 first edition to reflect the exponential expansion of research and clinical data amassed in the intervening years. Each chapter was written and reviewed by the foremost authorities in neuropsychiatry, neurology, rehabilitation medicine, and the other specialties who assess, diagnose, and treat these patients. The revisions and additions to this comprehensive volume were made to ensure that the scope and coverage is both up-to-date and down-to-earth. Key features include: New chapters on epidemiology, neuropathology, and genetics of TBI; new chapter on TBI in the military emphasizing the unique feature of blast injury; A new chapter on posttraumatic stress disorder (PTSD), which emphasizes the common co-occurrence of TBI and PTSD in both combat and other settings; Enhanced coverage of psychopharmacology and psychotherapy for the psychiatric symptoms associated with TBI; Information on the social ramifications of TBI so that clinicians will better understand and help their patients cope with the complex legal, financial, and insurance-based struggles their patients who have sustained TBI encounter; Each chapter concludes with essential points and key references to focus attention and consolidate learning; A foreword written by Bob Woodruff (the ABC World News correspondent who sustained a TBI while covering the war in Iraq) and his wife, Lee Woodruff, who underscore that although this volume is intended to be read primarily by professionals, patients and families may also find the information in the textbook to be of keen interest and practical application.
  • Therapy in sleep medicine 2012
    2012 ClinicalKey
    Introduction to sleep medicine -- Background to sleep medicine therapeutics -- Pharmacology principles -- Insomnias -- Sleep-related breathing disorders -- Central hypersomnolence -- Movement disorders affecting sleep -- Circadian rhythm disorders -- Therapy in pediatric sleep-related disorders -- Parasomnias in adults -- Sleep-related medical disorders -- Neurologic disorders and sleep -- Therapy of sleep disturbances associated with psychiatric disorders -- Special situations and the future -- Appendix: Effects of drugs on sleep.
  • Thoracic outlet syndrome (TOS) is a condition estimated to affect as many as 80 of every 1000 patients in the US alone. While estimates vary widely based in part on lack of consensus as to the definition of the syndrome, as many as 3000 first rib resections are performed annually in the US. TOS comprises at least three separate conditions. The most common, neurogenic TOS, refers to the condition where the brachial plexus is compressed at the scalene triangle or retropectoral space, and is manifest as local and extremity pain and neurologic symptoms. Venous TOS refers to the situation where the subclavian vein is compressed by the structures making up the costoclavicular junction, and presents as acute or chronic venous thrombosis or injury or occasionally intermittent positional obstruction. Finally, arterial TOS refers to the situation where arterial injury occurs as the result of abnormal bony or ligamentous structures at the outlet, and presents as occlusion of or embolization from an abnormal artery in this area. Thoracic Outlet Syndrome brings together many experts who treat this disease and are leaders in their fields. While it can certainly be read in its entirety (and should, by all who concentrate on this condition), it is designed to be a clinical reference, residing on a shelf in a busy surgical, vascular or neurologic clinic where individual chapters can be quickly referenced. As such, the chapters are thorough, but concise and useful to answer when a specific question arises in the course of daily practice.
  • History of transient ischemic attack definition / Mohr, J.P. -- The concept of acute cerebrovascular syndrome / Uchiyama, S. -- Transient ischemic attack as a medical emergency / Okada, Y. -- TIA clinic : a major advance in management of transient ischemic attacks / Lavalle, P.; Amarenco, P. -- Risk scores for transient ischemic attack / Wolf, M.E.; Held, V.E.; Hennerici, M.G. -- Epidemiology of transient ischemic attack / Kokubo, Y. -- Symptoms of transient ischemic attack / Kim, J.S. -- Guidelines for management of patients with transient ischemic attack / Uehara, T.; Minematsu, K. -- Radiological examinations of transient ischemic attack / Tung, C.E.; Olivot, J.M.; Albers, G.W. -- Neurosonological examinations of transient ischemic attack / Sharma, V.K.; Wong, K.S.L. -- Stroke subtypes and interventional studies for transient ischemic attack / Lavalle, P.; Amarenco, P. -- Antithrombotic therapy in transient ischemic attack patients / Held, V.E.; Wolf, M.E.; Hennerici, M.G.
  • "Recent advances in brain science measurement technology have given researchers access to very large-scale time series data such as EEG/MEG data (20 to 100 dimensional) and fMRI (140,000 dimensional) data. To analyze such massive data, efficient computational and statistical methods are required. Time Series Modeling of Neuroscience Data shows how to efficiently analyze neuroscience data by the Wiener-Kalman-Akaike approach, in which dynamic models of all kinds, such as linear/nonlinear differential equation models and time series models, are used for whitening the temporally dependent time series in the framework of linear/nonlinear state space models. Using as little mathematics as possible, this book explores some of its basic concepts and their derivatives as useful tools for time series analysis. Unique features include: statistical identification method of highly nonlinear dynamical systems such as the Hodgkin-Huxley model, Lorenz chaos model, Zetterberg Model, and more Methods and applications for Dynamic Causality Analysis developed by Wiener, Granger, and Akaike state space modeling method for dynamicization of solutions for the Inverse Problems heteroscedastic state space modeling method for dynamic non-stationary signal decomposition for applications to signal detection problems in EEG data analysis An innovation-based method for the characterization of nonlinear and/or non-Gaussian time series An innovation-based method for spatial time series modeling for fMRI data analysis The main point of interest in this book is to show that the same data can be treated using both a dynamical system and time series approach so that the neural and physiological information can be extracted more efficiently. Of course, time series modeling is valid not only in neuroscience data analysis but also in many other sciences and engineering fields where the statistical inference from the observed time series data plays an important role"--Provided by publisher.
  • Tinnitus 2012
    Historical Reflections on Current Issues in Tinnitus / Jos J. Eggermont and Fan-Gang Zeng -- Behavioral Tests for Tinnitus in Animals / Henry E. Heffner and Rickye S. Heffner -- Molecular Mechanism of Tinnitus / Marlies Knipper, Marcus Müller and Ulrike Zimmermann -- The Cochlea and the Auditory Nerve as a Primary Source of Tinnitus / Régis Nouvian, Michel Eybalin and Jean-Luc Puel -- Dorsal Cochlear Nucleus: Somatosensory-Auditory Interactions in Tinnitus / Susanne Dehmel, Seth D. Koehler and Susan E. Shore -- The Inferior Colliculus: Involvement in Hyperactivity and Tinnitus / Donald Robertson and Wilhelmina Mulders -- Cortex: Way Station or Locus of the Tinnitus Percept? / Jos J. Eggermont -- Human Brain Imaging of Tinnitus / Jennifer R. Melcher -- The Psychophysics of Tinnitus / Brian C. J. Moore -- Stimulating the Auditory System to Treat Tinnitus: From Alleviating the Symptoms to Addressing the Causes / Arnaud J. Noreña -- Treatment: Pharmacological, Repetitive Transcranial Magnetic Stimulation, Epidural Stimulation, and Deep Brain Stimulation / Berthold Langguth, Dirk De Ridder, Tobias Kleinjung and Ana Belén Elgoyhen.
  • Overview of toll-like receptors in the CNS / Tammy Kielian -- Toll-like receptors in bacterial meningitis / Uwe Koedel -- Toll-like receptors in brain abscess / Nilufer Esen and Tammy Kielian -- Toll-like receptors in CNS viral infections / Hyeon-Sook Suh, Celia F. Brosnan and Sunhee C. Lee -- Toll-like receptors in CNS parasitic infections / Bibhuti B. Mishra, Uma Mahesh Gundra and Judy M. Teale -- Toll-like receptors in neurodegeneration / Trevor Owens -- Toll-like receptors in spinal cord injury / Kristina A. Kigerl and Phillip G. Popovich -- Toll-like receptors in Alzheimer's disease / Gary E. Landreth and Erin G. Reed-Geaghan -- Toll-like receptors in multiple sclerosis / Michael K. Racke and Phil D. Drew -- Toll-like receptors in peripheral nerve injury and neuropathic pain / Donghoon Kim, Soojin Lee and Sung Joong Lee.
  • Congenital and developmental -- Attenuation and signal abnormality -- Masses and masslike lesions -- Vasculature and cerebrospinal fluid spaces -- Calvarium and skull base -- Temporal bone -- Sinonasal -- Maxillofacial -- Neck (including spaces) -- Orbits.
  • The book explains how to understand cognition in terms of brain anatomy, physiology and chemistry, using an approach adapted from techniques for understanding complex electronic systems. These techniques create hierarchies of information process based descriptions on different levels of detail, where higher levels contain less information and can therefore describe complete cognitive phenomena, but are more approximate. The nature of the approximations are well understood, and more approximate higher level descriptions can therefore be mapped to more precise detailed descriptions of any part of a phenomenon as required. Cognitive phenomena, the anatomy and connectivity of major brain structures, neuron physiology, and cellular chemistry are reviewed. Various cognitive tasks are described in terms of information processes performed by different major anatomical structures. These higher level descriptions are selectively mapped to more detailed physiological and chemical levels.--[Source inconnue].
  • Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
  • Electroconvulsive therapy : update and new research / Eser, D. ... [et al.] -- Repetitive transcranial magnetic stimulation effects in vitro and in animal models / Keck, M.E. -- Neuroimaging of repetitive transcranial magnetic stimulation effects on the brain / George, M.S. ... [et al.] -- Efficacy and safety of prefrontal repetitive transcranial magnetic stimulation in affective disorders / Padberg, F. ... [et al.] -- Repetitive transcranial magnetic stimulation in augmentation of antidepressant drugs / Ortega Rumi, D.O. ... [et al.] -- Transcranial magnetic stimulation versus electroconvulsive therapy for the treatment of more severe major depression / Janicak, P.G. ... [et al.] -- Transcranial magnetic stimulation in schizophrenia / Odebrecht Rosa, M. ... [et al.] -- Repetitive transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder and other anxiety disorders / Pridmore, S., Marcolin, M.A., Mansur, C.G. -- Repetitive transcranial magnetic stimulation in non-psychiatric disorders : pain, Parkinson's disease, stroke, tinnitus / Lefaucheur, J.-P, Khedr, E.M. -- Induction and modulation of neuroplasticity by transcranial direct current stimulation / Nitsche, M.A. ... [et al.] -- Magnetic seizure therapy for the treatment of depression / Lisanby, S.H., Peterchev, A. -- Theta burst stimulation / Huang, Y.-Z., Rothwell, J.C. -- Transcranial magnetic stimulation of deep brain regions : principles and methods / Roth, Y., Padberg, F., Zangen, A.
  • Principles of cerebral ultrasound contrast imaging / Powers, J., Averkiou, M. -- Physical principles of microbubbles for ultrasound imaging and therapy / Stride, E. -- Ultrasound bio-effects and safety considerations / Ter Haar, G. -- Intima-media thickness of carotid arteries / Touboul, P.-J. -- Functional TCD : regulation of cerebral hemodynamics, cerebrovascular autoregulation, vasomotor reactivity, neurovascular coupling / Wolf, M.E. -- Intracranial perfusion imaging with ultrasound / Meairs, S., Kern, R. -- Parenchymal imaging in movement disorders / Fernandes, R.C.L., Berg, D. -- Sonothrombolysis / Meairs, S. -- Non-invasive transcranial brain ablation with high-intensity focused ultrasound / Jenne, J.W. -- Ultrasound-induced blood-brain barrier opening for drug delivery / Alonso, A.
  • Pt. 1. Theoretical overview -- pt. 2. Mechanisms and targets -- pt. 3. Translational models -- pt. 4. De-risking of drug candidates -- pt. 5. Therapy delivery -- pt. 6. Therapy development -- pt. 7. Clinical trial design.
  • Trauma surgery has increasingly become a specialized field inspired by different principles and philosophy. A good trauma surgeon is a surgeon who knows how to perform abdominal vascular, thoracic, urologic, gynecologic, and orthopaedic procedures and is able to repair multiple traumatic injuries in the best sequence possible. In this first volume, practical, up-to-date guidance is provided on the optimal critical care and ICU management of trauma patients. In addition, individual chapters focus on specific injuries in orthopaedic trauma (and especially spinal trauma) and neurotrauma, with the aim of providing a fresh view of the surgical approach and practical suggestions for improving the skills of treating surgeons. Educational issues and the organization of a trauma center are also covered. The volume will be a handy pocket guide for trainee surgeons and any surgeon, physician, or nurse who treats trauma patients. It will be particularly relevant for emergency department physicians, critical care and ICU doctors, orthopaedic surgeons, neurosurgeons, and professionals responsible for trauma care and decision making, programs of trauma education, or organization of a trauma center.
  • Overview of TBI / David F. Moore, Michael S. Jaffee, Geoffrey Ling -- Imaging diagnosis of TBI / Tuong H. Le, Shirley I. Stiver, Alisa D. Gean -- Neurocognitive assessment of mTBI / W. Huw Williams, Seb Potter, Helen Ryland, Philip Yates, James Tonks & Adam Reuben -- Management of moderate and severe TBI / Scott A. Marshall, Randy Bell, Rocco A. Armonda, Geoffrey S.F. Ling -- Sports concussion / Sharon R. Weeks, Jack W. Tsao -- Blast-related concussion / Carson Lawall -- Sleep/wake disturbances in mild traumatic brain injury patients / Michael Russo, Aimee Alphonso, Ian Murphy -- Vestibular consequences of mTBI / Michael E Hoffer, Kim Gottshall, Erik S. Viirre -- Post-traumatic headache / Jay C. Erickson, Brett J. Theeler -- Seizures after TBI / John Betjemann, Karen Parko -- Endocrine disturbances following TBI / Victoria Tepe, Arthur Guerrero -- Confronting mild TBI and Co-occurring PTSD symptoms in combat deployed service members / Justin S. Campbell, Jeffrey H. Greenberg, Jennifer M. Weil -- Behavioral and psychiatric comorbidities of TBI / Robert L. Collins, Nicholas J. Pastorek, Andra L. Teten, Thomas A. Kent -- Rehabilitation of TBI / Mel Glenn -- Interventions to improve cognitive functioning after TBI / Anthony J.-W. Chen, Tatjana Novakovic-Agopian -- Current diagnostic and therapeutic challenges / Donald W. Marion.
  • Traumatic brain injury. Parts I-II pt. 1-2, 2015
    pt. 2 ScienceDirect
    The Handbook of Clinical Neurology volume on traumatic brain injury (TBI) provides the reader with an updated review of emerging approaches to traumatic brain injury (TBI) research, clinical management and rehabilitation of the traumatic brain injury patient. Chapters in this volume range from epidemiology and pathological mechanisms of injury, and neuroprotection to long-term outcomes with a strong emphasis on current neurobiological approaches to describing the consequences and mechanisms of recovery from TBI. The book presents contemporary investigations on blast injury and chronic traumatic encephalopathy, making this state-of-the-art volume a must have for clinicians and researchers concerned with the clinical management, or investigation, of TBI.
  • Anatomical overview of the central and peripheral nervous system -- Physiology of the nervous system -- Characterization of tremor -- Principal disorders associated with tremor -- Quantification of tremor -- Mechanisms of tremor -- Treatments.
  • Historical Perspectives on Trigeminal Nerve Injuries -- Classification of Nerve Injuries -- Etiology and Prevention of Nerve Injuries -- Injection Injuries of the Trigeminal Nerve -- Third Molar Injuries of the Trigeminal Nerve -- Dental Implant-Related Injuries of the Trigeminal Nerve -- Nerve Repositioning Injuries of the Trigeminal Nerve -- Orthognathic Injuries of the Trigeminal Nerve -- Nerve Injury and Regeneration -- Clinical Evaluation of Nerve Injuries -- Imaging of the Trigeminal Nerve -- Nonsurgical Management of Trigeminal Nerve Injuries -- Surgical Management of Lingual Nerve Injuries -- Surgical Management of Inferior Alveolar Nerve Injuries -- Surgical Management of Facial Nerve Injuries -- Nerve Grafts and Conduits -- Complications of Trigeminal Nerve Repair -- Neurosensory Rehabilitation -- Outcomes of Trigeminal Nerve Repair -- Guidelines for Diagnosis and Treatment of Trigeminal Nerve Injuries.
  • Triptans for migraine 2012
    Future Med
    Triptans for migraine / Hans-Christoph Diener & David W. Dodick -- Pathophysiology of migraine & triptan mechanism of action / Rashmi B. Halker & Bert B. Vargas -- Overview of oral triptans / Michail Vikelis & Alan M. Rapoport -- The non-orally administered triptans / Todd J. Schwedt -- Triptans for migraine in special populations : pediatric migraine / Paul Winner -- Migraine and triptan therapy in an aging population : weighing risks against benefits / Roger K. Cady & Kathleen Farmer -- Triptans for migraine in special populations : migraine during pregnancy and lactation / Sylvia Lucas -- Treatment recommendations & consensus guidelines / Hans-Christoph Diener & Stephen D. Silberstein -- Index.
  • Vol. 1. Gliomas: Glioblastoma (part 1) -- Vol. 2. Gliomas: Glioblastoma (part 2) -- Vol. 3. Brain tumors (part 1) -- Vol. 4. Brain tumors (part 2) -- Vol. 5. Astrocytomas, hemangioblastomas, and gangliomas -- Vol. 6. Spinal Tumors (Part 1) -- Vol. 7. Meningiomas and Schwannomas -- Vol. 8. Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma --Vol. 9. Lymphoma, supratentorial tumors, glioneuronal tumors, gangliogliomas, neuroblastoma in adults, astrocytomas, ependymomas, hemangiomas, and craniopharygiomas -- Vol. 10. Pineal, pituitary, and spinal tumors -- Vol. 11. Pineal, pituitary and, spinal tumors -- Vol. 12. Molecular mechanisms, children's cancer, treatments, and radiosurgery -- Vol. 13. Types of tumors, diagnosis, ultrasonography, surgery, brain metastasis, and general CNS diseases -- Vol. 14. Glioma, meningioma, neuroblastoma, and spinal tumors
  • Adding to a vitally important cycle of publications covering the latest research developments in our understanding of neoplasms affecting the human central nervous system, this edition focuses on numerous aspects of pineal, pituitary, and spinal tumors. As with the previous volumes in the series, this latest work addresses a central imperative in cancer research--the need to standardize classifications, written definitions and investigative guidelines in order to achieve a measure of shared objectivity among academics engaged in one of the most important medical endeavors of our era. It brings together the very latest work by oncologists, neurosurgeons, physicians, research scientists, and pathologists, providing the medical community with a wealth of data and results that, taken together, will advance the cause of cancer research. The volume synthesizes work on diagnosis, drug development, and therapeutic approaches that are typically scattered in a variety of journals and books. It features promising recent work in applying molecular genetics to clinical practice and evidence-based therapy, covering molecular profiling of tumors as well as a number of surgical treatments such as resection and radiosurgery. Together with its counterpart publications, it represents a much-needed central resource that will inform and guide future research efforts.
  • Classification/Diagnosis of Brain Tumors Using Discriminant Function Analysis -- Neuronal Differentiation in the Adult Brain: CDK6 as the Molecular Regulator -- Prolactinomas: Role of VEGF, FGF-2 and CD31 -- Human Brain Tumor Growth: Role of Aquaporins -- Molecular and Functional Characterization of Human Adipocytes -- Inhibition of Neuroblastoma Progression by Targeting Lymphangiogenesis: Role of an Endogenous Soluble Splice-Variant of VEGFR-2 -- Hyperinsulinemia Tends to Induce Growth Without Growth Hormone in Children with Brain Tumors After Neurosurgery -- Childhood Brain Tumours: Proton Beam Therapy -- Pathogenesis of Medulloblastoma: Role of Molecular Genetic Alterations -- Medulloblastomas: Survival Differences Between Children and Adults -- Survivors of Childhood Cancer: Risk of Glioma and Meningioma Following Radiotherapy -- Survivors of Childhood Cancer: Risk of New Primary Neoplasms of the CNS -- Brain Tumor Typing and Therapy Using Combined Ex Vivo Magnetic Resonance Spectroscopy and Molecular Genomics -- Atlas-Based Segmentation of Tumor-Bearing Brain Images -- Nonthermal Irreversible Electroporation as a Focal Ablation Treatment for Brain Cancer -- The Role of Whole Brain Radiation Therapy for Metastatic Brain Tumors -- Craniotomy for Intracranial Tumors: Role of Postoperative Hematoma in Surgical Mortality -- Pituitary Adenomas: Treatment Using the Endonasal Approach -- Intracranial Tumors: Treatment with Endoscopic Neurosurgery -- Incidence of Recraniotomy for Postoperative Infections After Surgery for Intracranial Tumors -- Transsphenoidal Surgery for Non-Adenomatous Tumors: Effect on Pituitary Function -- Treatment of Brain Tumors: Electrochemotherapy -- Comparison of Navigated Transcranial Magnetic Stimulation to Direct Electrical Stimulation for Mapping the Motor Cortex Prior to Brain Tumor Resection -- The Role of Glutathione and the Glutathione-Linked Enzyme Systems in Brain Tumor Drug Resistance -- Drugs for Primary Brain Tumors: An Update -- Neurosurgical Treatment for Brain Metastases: Clinical Features, Operative Strategies, Recurrence and Survival -- Image-Guided Radiosurgery for Hypothalamic Hamartomas -- Image-Guided Stereotactic Radiosurgery for Spinal Pathology -- Image-Guided Stereotactic Radiosurgery for Optic Nerve Sheath Meningiomas -- Brain Metastases: The Application of Stereotactic Radiosurgery and Technological Advances -- Treatment of Chordomas by Stereotactic Radiosurgery with a Linear Accelerator: Comparison with Other Modes.
  • Volume 13: Pineal, Pituitary, and Spinal Tumors is organized in six sections, for convenience and quick access to critical information. Section I, Types of Tumors includes a chapter on molecular characterization of Embryonal tumors, a chapter on diagnosis of metastatic oligodendroglioma using fine-needle aspiration cytology, one covering intra-arterial chemotherapy of oligodendroglial tumors and another on the role of cyclooxygenase-2 in the development and growth of Schwannomas, and others, closing with a chapter on trigeminal neuralgia with cerebellopontine angle tumors. Section II, Diagnosis, includes two chapters on cell counting in histopathologic slides of tumors. Section III offers three chapters which discuss aspects of intraoperative ultrasonography. Section IV covers brain tumor surgery, and Section V surveys Brain Metastasis. The final section offers a wide-ranging review of General Diseases, with chapters on, among others, Alexander Disease; Lipoma; Transplantation of human umbilical cord blood mononuclear cells in cases of neonatal hypoxic-ischemic brain damage; and a chapter discussing the use of mobile phones and brain cancer risk in children. Like its twelve predecessors in the series, this volume merits distinction for its thorough approach, its roster of 78 distinguished contributors representing 14 different countries and its detailed examination of leading-edge technology and methods.
  • v. 2, 2012 Springer
  • v. 4 Springer
  • Pt. 1. Astrocytomas : diagnosis and biomarkers -- pt. 2. Astrocytomas : therapy -- pt. 3. Astrocytomas : prognosis -- pt. 4. Hemangioblastoma -- pt. 5. Ganglioglioma.
  • This volume contains information on the diagnosis, therapy, and prognosis of spinal tumors. Various aspects of different major types of spinal tumors (astrocytomas, ependymomas, and oligodendroglioma) are discussed. Insights into the understanding of molecular pathways involved in tumor biology are explained. Classification of intradural spinal tumors, including the percentages of each of the three major types, is detailed. Symptoms, radiological features, and clinicopathological parameters of spinal cord tumors are explained. Diagnosis, outcome, and prognosis of primary spinal cord and oligodendroglioma are discussed. Diagnosis of some other spinal tumors (e.g., pilomyxoid and chordomas) is also explained. The useful role of neuroimaging in diagnosing spinal teratoid/rhabdoid and gangliogliomas is included. A wide variety of treatments of a number of spinal cord tumor types are presented in detail. Therapies discussed include chemotherapy, surgery, radiosurgery, stereotactic radiosurgery, Cyberknife stereotactic radiotherapy, standard radiation alone, and rhenium-186 intracavity radiation. Also are duiscussed embolozation and spondylectomy. The usefulness of transplantation of human embryonic stem cells-derived oligodendrocyte progenitors and motoneuron progenitors in the repair of injured spinal cord is emphasized. Symptoms of the advent of spinal tumors are pointed out. Introduction to new technologies and their applications to spinal cord tumor diagnosis, treatment, and therapy assessment are explained
  • This volume offers in-depth discussion of two types of brain tumors - meningioma and schwannoma - covering diagnosis, therapy, and prognosis. It covers molecular genetics, and such therapeutic methods as neurosurgery, gamma knife radiosurgery, and adjuvant radiation
  • With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma. Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targetedand thus more effective.
  • The ninth volume in this essential series discusses key advances in our understanding of neoplasms in the human central nervous system. This publication deals with various aspects of nine separate types of brain tumors. With 70 contributors from 17 nations, this edition offers an unrivalled thoroughness and breadth of coverage that includes the very latest research results on the following tumor types: astrocytoma, lymphoma, supratentorial and glioneuronal tumors, gangliogliomas, neuroblastoma in adults, hemangioma, and ependymoma.The content introduces new technologies and their applications
  • Print Material
  • Homeostasis involves a delicate interplay between generative and degenerative processes to maintain a stable internal environment. In biological systems, equilibrium is established and controlled through a series of negative feedback mechanisms driven by a range of signal transduction processes. Failures in these complex communication pathways result in instability leading to disease. Cancer represents a state of imbalance caused by an excess of cell proliferation. In contrast, neurodegeneration is a consequence of excessive cell loss in the nervous system. Both of these disorders exhort profound tolls on humanity and they have been subject to a great deal of research designed to ameliorate this suffering. ...--Foreword.
  • Section I. Foundations for clinical practice in neurological rehabilitation. Foundations for clinical practice / Darcy A. Umphred, Rolando T. Lazaro and Margaret L. Roller -- Health and wellness: The beginning of the paradigm / Janet R. Bezner -- Movement analysis across the life span / Dale Scalise-Smith and Darcy A. Umphred -- Contemporary issues and theories of motor control, motor learning, and neuroplasticity / Margaret L. Roller ... [] -- The limbic system : Influence over motor control and learning / Darcy A. Umphred, Marcia Hall Thompson and Therese Marie West -- Psychosocial aspects of adaptation and adjustment during various phases of neurological disability / Rochelle McLaughlin and Gordon U. Burton -- Differential diagnosis phase 1 : Medical screening by the therapist / William G. Boissonnault and Darcy A. Umphred -- Differential diagnosis phase 2 : Examination and evaluation of functional movement activities, body functions and structures, and participation / Rolando T. Lazaro, Margaret L. Roller and Darcy A. Umphred -- Interventions for clients with movement limitations / Darcy A. Umphred ... [] -- Payment systems for services : Documentation through the care continuum / Barbara Edmison and John G. Wallace, Jr. -- Section II. Rehabilitation management of clients with neurological system pathology. Neonates and parents : Neurodevelopmental perspectives in the neonatal intensive care unit and follow-up / Jane K. Sweeney, Teresa Gutierrez and Joanna C. Beachy -- Management of clinical problems of children with cerebral palsy / Claudia R. Senesac -- Genetic disorders : A pediatric perspective / Sandra G. Bellamy and Eunice Yu Chiu Shen -- Learning disabilities and developmental coordination disorder / Stacey E. Szklut and Darbi Breath Philibert -- Spina bifida : A congenital spinal cord injury / Kristin J. Krosschell and Mari Jo Pesavento -- Traumatic spinal cord injury / Myrtice B. Atrice ... [] -- Neuromuscular diseases / Ann Hallum and Diane D. Allen -- Beyond the central nervous system : Neurovascular entrapment syndromes / Bradley W. Stockert, Laura J. Kenny and Peter I. Edgelow -- Multiple sclerosis / Gail L. Widener -- Basal ganglia disorders / Marsha E. Melnick -- Movement dysfunction associated with cerebellar damage / Susanne M. Morton and Amy J. Bastian -- Balance and vestibular dysfunction / Leslie K. Allison and Kenda Fuller -- Movement dysfunction associated with hemiplegia / Susan D. Ryerson -- Traumatic brain injury / Patricia A. Winkler -- Brain tumors / Corrie J. Stayner, Rachel M. Lopez and Karla M. Tuzzolino -- Inflammatory and infectious disorders of the brain / Judith A. Dewane -- Aging, dementia, and disorders of cognition / Osa Jackson Schulte, James Stephens and Joyce Ann -- Section III. Neurological disorders and applications issues. Disorders of vision and visual-perceptual dysfunction / Laurie Ruth Chaikin -- Pelvic floor treatment of incontinence and other urinary dysfunctions in men and women / Beate Carriere -- Cardiovascular and pulmonary system health in populations with neurological disorders / Marilyn Mackay-Lyons -- Human immunodeficiency virus infection : Living with a chronic illness / Kerri Sowers, Mary Lou Galantino and David M. Kietrys -- Pain management / Annie Burke-Doe -- Electrophysiological testing and electrical stimulation in neurological rehabilitation / Alain Claudel ... [] -- Orthotics : Evaluation, intervention, and prescription / Heidi Truman and Walter Racette -- Management of chronic impairments in individuals with nervous system conditions / Myla U. Quiben -- Impact of drug therapy on patients receiving neurological rehabilitation / Annie Burke-Doe and Timothy J. Smith -- Use of medical imaging in neurorehabilitation / Rolando T. Lazaro and Darcy A. Umphred -- Integrating technology into clinical practice in neurological rehabilitation / Katie Byl ... [] -- Complementary and alternative therapies : Beyond traditional approaches to intervention in neurological diseases and movement disorders / Darcy A. Umphred, Carol M. Davis and Mary Lou Galantino.
  • Integrating basic and clinical neuroscience perspectives, this book presents a comprehensive perspective on state-of-the-art research in epidemiology, genetics, and clinical neuroscience and neural systems implicated in autism. This book seeks to stimulate new directions for autism research on etiology, pathophysiology, and the development of new drug treatment. An underlying theme focuses on the potential for future research given the availability of the human, mouse, and other genomes. The text also explores the role of autism in society, including health economics and advocacy issues of interest to legislators.
  • 1. Introduction -- 2. Discovery and validation of biomarkers based on computational models of normal and pathological hippocampal rhythms -- 3. DCM conductance based models and clinical applications -- 4. Computational models of closed-loop deep brain stimulation -- 5. A multiscale "working brain" model -- 6. How to render neural fields more realistic -- 7. Multilevel computational modelling in epilepsy: classical studies and recent advances -- 8. Computational modeling of neuronal dysfunction at molecular level validates the role of single neurons in circuit functions in cerebellum granular layer -- 9. Modelling cortical and thalamocortical synaptic loss and compensation mechanism in Alzheimer's disease -- 10. Toward networks from spikes -- 11. Epileptogenic networks: applying network analysis techniques to human seizure activity -- Index.
  • The aging population and the importance of vascular dementia / Kelly L. Lange and Robert H. Paul -- Clinical forms of vascular dementia / Gustavo C. Román -- Neuropathological substrates of vascular ischemic dementia / Kurt A. Jellinger -- Diagnosis of vascular dementia : conceptual challenges / José G. Merino and Vladimir Hachinski -- Cerebral hemodynamics in the elderly / Jorge M. Serrador and Lewis A. Lipsitz -- The cadasil syndrome and other genetic causes of stroke and vascular dementia / Stephen Salloway and Sophie Desbiens -- Estrogen, the cerebrovascular system, and dementia / Sharon X.C. Yang and George A. Kuchel -- Hypertension and cerebrovascular disease : effects of hypertension on young and middle-aged rhesus monkeys / Mark B. Moss and Elizabeth M. Jonak -- The cognitive profile of vascular dementia / Angela Lee Jefferson ... [et al.] -- Progression of cognitive impairments associated with cerebrovascular disease / Sally Stephens ... [et al.] -- Neuropsychiatric correlates of vascular injury : vascular dementia and related neurobehavioral syndromes / Anand Kumar, Helen Lavretsky, and Ebrahim Haroon -- Functional impairment in vascular dementia / Patricia A. Boyle and Deborah Cahn-Weiner -- Functional brain imaging of cerebrovascular disease / Ronald Cohen ... [et al.] -- Contributions of subcortical lacunar infarcts to cognitive impairment in older persons / Dan Mungas -- White matter hyperintensities and cognition / David J. Moser, Jason E. Kanz, and Kelly Davis Garrett -- Poststroke dementia : the role of strategic infarcts / Anelyssa D'Abreu and Brian R. Ott -- Understanding incidence and prevalence rates in mixed dementia / John Gunstad and Jeffery Browndyke -- Vascular basement membrane abnormalities and alzheimer's disease / Edward G. Stopa, Brian D. Zipser, and John E. Donahue -- Amyloid beta and the cerebral vasculature / Paula Grammas -- Cerebrovascular disease and the expression of Alzheimer's disease / Margaret M. Esiri and Zsuzsanna Nagy -- The neuropsychological differentiation between Alzheimer's disease and subcortical vascular dementia / David J. Libon ... [et al.] -- Pharmacological treatment of vascular dementia / Timo Erkinjuntti ... [et al.] -- Understanding and managing caregiver burden in cerebrovascular disease / Geoffrey Tremont, Jennifer Duncan Davis, and Mary Beth Spitznagel -- Quality of life in patients with vascular dementia / Rebecca E. Ready and Brian R. Ott -- Approaches to neuroprotection and recovery enhancement after acute stroke / Marc Fisher and Magdy Selim.
  • Basic principles of UVI / Ana Maria Braz and Jaime Leal Pamplona -- Clinical applications of UVI / Ana Maria Braz, Maria Madalena Patricio, and Joana Ramalho -- Novel applications of UVI / Elsa Azevedo and Pedro Castro -- Basic principles of CTA / Margareth Kimura and Mauricio Castillo -- Intracranial CTA / Isabel R. Fragata and Joana Ramalho -- Extra-cranial CTA / Tiago Baptista and João Lopes Reis -- Basic principles of time-of- flight magnetic resonance angiography (TOF MRA) and MRV (2D and 3D) / Hugo A. Ferreira and Joana Ramalho -- Basic principles of phase contrast magnetic resonance angiography (PC MRA) and MRV / Hugo A. Ferreira and Joana Ramalho -- Time-of-flight magnetic resonance angiography (TOF MRA) and MRV : clinical applications / Mauricio Castillo, Juan Camilo Márquez and Francisco Jose Medina -- Phase contrast magnetic resonance angiography (PC MRA) and flow analysis : clinical applications / Pedro Vilela -- Contrast-enhanced MRA fundamentals and clinical applications / Khurram Javed and Mauricio Castillo -- Intracranial magnetic resonance angiography (MRA), 1.5T versus 3T : advantages and disadvantages / Sara Safder, Benjamin Huang, and Mauricio Castillo -- Time-resolved techniques / Nuno Almeida, David Monteiro, and Daniela Seixas -- DSA : basic principles / Mauricio Castillo -- DSA in clinical practice / Yueh Z. Lee and Mauricio Castillo -- Advanced and future DSA applications / Pedro Vilela -- CT perfusion, basic concepts and clinical applications / Joana Ramalho and Isabel R. Fragata -- Dynamic susceptibility contrast-enhanced MRI perfusion : basic principles and clinical applications / Francisco Medina Valencia, Mauricio Castillo, and Juan Marquez -- Arterial spin labeling (ASL) perfusion basic concepts, artifacts, and clinical applications / Debora Bertholdo and Mauricio Castillo -- Imaging of carotid plaque / Sangam Kanekar -- Basic concepts and clinical applications of intravascular imaging hideki / Sitahara, Peter J. Fitzgerald, Paul G. Yock, and Yasuhiro Honda -- Pediatric vascular imaging techniques and clinical applications / Carla R. Conceio, Rita Lopes da Silva, and Joana Ramalho.
  • Vascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma.Twenty nine chapters are arranged in three sections:Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities. The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury.
  • Vasovagal syncope 2015
    This book is exceptional in being devoted solely to vasovagal syncope (VVS), the most frequent cause of transient loss of consciousness in the general population. All aspects of VVS are covered, including epidemiology, pathophysiology, diagnosis and differential diagnosis, prognosis, therapy and implications for particular activities such as work, driving and physical activity. The context for the book is that about half of the population suffer from this type of loss of consciousness during their lifetime and then often call for general practitioner and/or emergency room assistance. While many pathophysiological aspects of VVS have been clarified, others remain elusive. The diagnosis of VVS may be easy, but it is sometimes challenging. From the therapeutic standpoint, few evidence-based therapies have been established and the large majority of treatments remain unsatisfactory. Vasovagal Syncope presents the latest evidence on all these issues and will be of value for internists, cardiologists, neurologists, emergency physicians and general practitioners.
  • Part I. Fundamentals -- Nomenclature and epidemiology -- Basic sciences, clinical evaluation and investigations -- Part II. Clinical conditions -- Meniere's disease -- Benign paroxysmal positional vertigo (BPPV) -- Vestibular migraine -- Cervical vertigo/labyrinthitis/ototoxicity -- Chronic suppurative otitis media (CSOM) -- Central causes -- General causes -- Paediatric clinical conditions -- Part III. Rehabilitation and ethical issues -- Rehabilitation -- Vertigo in the elderly: quality of life and some ethical issues.
  • Many congenitally deaf infants and children suffer vestibular failure, which produces problems with their postural control, locomotion, and gait. However it is known that these children can eventually catch up with their normal balance control status in terms of development and growth as a result of central vestibular compensation. In Vertigo and Balance Disorders in Children the author provides comprehensive and integrative information on the vestibular system. The materials presented range from the history of its study, basic anatomy and physiology of vestibular organs, and the mechanism of balance and motor function development, to clinical aspects of vestibular disorders including their evaluation and pediatric neurology. Although there have been books discussing postural responses of infants and children with vestibular disorders, this is the first to present the influence of peripheral vestibular disorders and central vestibular compensation comprehensively. This book will benefit not only practitioners in this field such as pediatric otolaryngologists, pediatricians, and neurologists treating both children and adults, but also clinical specialists such as neonatologists, physical therapists, and speech therapists, helping them to better care for patients with vestibular failure.
  • "This book describes in detail rehabilitation protocols specific for those disorders that most frequently induce vertigo and dizziness. In particular, it highlights exercise protocols that will enable the best result to be obtained within the shortest time and with the most enduring therapeutic effect. Drawing on their personal experience, the authors describe physical exercises that will prove effective in delivering vestibular rehabilitation all over the world, regardless of the rehabilitation tools available. The protocol standardization and the reduction in instrumental rehabilitation mean that even though some individual tailoring is required, it will be possible to plan cost-effective rehabilitation within both the institutional and the private practice setting. The presented protocols cover vertigo in a wide range of conditions, including acute and chronic vestibular loss, vestibular ataxia, benign positional paroxysmal vertigo, Ménière's disease, dizziness in the elderly, whiplash-associated balance disorders, phobic postural vertigo, and autonomic vertigo. Helpful information is provided on clinical approach to vertigo and dizziness and on vestibular rehabilitation from Cawthorne-Cooksey onward. The quantification of rehabilitation outcome and the role of life-style counseling are also discussed. By documenting effective functional and therapeutic approaches and presenting guidelines for each balance disorder, Vertigo Rehabilitation Protocols will be an invaluable resource for neurologists, ENT physicians, orthopedists, and rehabilitation specialists."--Publisher's website.
  • Vestibular migraine 2015
    Vestibular Migraine is a concise monograph that presents the scientific basis for the diagnosis and treatment of this common yet largely unrecognized cause of dizziness. Current knowledge of the features of the disorder is described, and clear guidance is provided on the differentiation of vestibular migraine from other conditions that induce dizziness, including M©♭ni©·reℓ́ℓs disease. Symptomatic treatment and the various prophylactic options are discussed and evaluated, and advice is also included on long-term treatment and the circumstances under which treatment should be discontinued. Approximately one-third of migraineurs experience dizziness that sometimes occurs in conjunction with the headaches but often arises separately. The vestibular symptoms in this population vary in frequency, severity, and duration; they are described as spinning or lightheadedness or both and are often exacerbated by position change. Ear fullness, tinnitus, and hearing loss are frequent complaints. Vestibular migraine is diagnosed by carefully obtaining a history: there are no pathognomonic blood, urine, or imaging studies. This book will be of interest to all physicians and other health care providers who deal with dizzy patients, including internists, family physicians, neurologists, otolaryngologists, and trainees in those specialties, as well as nurse practitioners and physician assistants.
  • This book provides a multidisciplinary approach to vestibular migraine and related syndromes in which dizziness is the most predominant feature. Starting from the neurological point of view, the pathophysiology, classification, neurophysiology, and therapy of migraine are discussed. Readers will learn how to recognize and properly treat vestibular migraine, which is often undiagnosed or misdiagnosed as Ménière's syndrome (a form of vertigo characterized by vertigo spells and hearing loss that presents comorbidity with migraine) or benign paroxysmal positional vertigo (in which patients experience brief episodes of vertigo, lasting from seconds to 1 minute, when they move their heads in a certain way). The described diagnostic and therapeutic strategies include the newest, state of the art approaches. Further aspects of migraine that are considered include hyperexcitability in the brain and the triad of migraine, dizziness, and anxiety. In addition, the imaging of migraine, and of vestibular migraine in particular, is discussed and clinical records are reported. Vestibular Migraine and Related Syndromes is based on the practical and clinical experiences of an authoritative group of well-known neurologists, ENT specialists, and neuro-otologists. It provides neurologists with a complete overview of relevant clinical features, otolaryngologists with clear descriptions of clinical aspects and the pathophysiology of migraine, and radiologists with guidance on the role of imaging techniques.
  • Machine generated contents note: pt. I Encephalitis -- Measles Virus Infection and Subacute Sclerosing Panencephalitis / Kalbiye Yalaz -- Epstein-Barr Virus and Cytomegalovirus Infections / Alex Tselis -- Herpes Simplex Virus Meningoencephalitis / Israel Steiner -- Progressive Multifocal Leukoencephalopathy / Allen J. Aksamit -- Varicella Zoster Virus Infections / Don Gilden -- pt. II Meningitis/Encephalitis/Poliomyelitis -- Enterovirus Infections / Burk Jubelt -- pt. III Retroviruses -- Human Immunodeficiency Virus Infection/AIDS / William Tyor -- Human T-Cell Lymphotropic Virus Type 1 Infection / Raya Massoud -- pt. IV Viral Zoonoses -- Rabies / Alan C. Jackson -- West Nile Virus Infection / Marc Fischer -- Japanese Encephalitis Virus Infection / Tom Solomon -- Chikungunya Virus Infection / Philippe Gasque -- Nipah Virus Infection / Chong-Tin Tan -- Viral Hemorrhagic Fevers / Marylou V. Solbrig -- pt. V Unconventional Agents -- Prion Diseases / Valerie L. Sim.
  • Sexual abuse, literay genius and a mind gone awry -- Development of early 20th century psychiatry and its failure -- Freud, the subconscious and Virginia Woolf -- Virginia Woolf's suicide -- Neuropsychiatry and suicide -- Brain networks, hormones, and genes implicated in depression -- Pathology of synapses in brain networks implicated in depression -- On the mechanism of action of an anti-depressant -- On the identification of drugs modulating epigenetic mechanisms in depression -- Brain networks in psychosis -- On mental illness -- Mind, mental illness and the stream of consciousness.
  • Visual Perception pt. 1-2.
    Fulltext (pt. 2) ScienceDirect
    Pt. 1. Fundamentals of vision: low and mid-level processes in perception -- Pt. 2. Fundamentals of awareness: multi-sensory integration and high-order perception.
  • V. 1 -- Sect. I Visual sensory system -- Sect. II The Autonomic nervous system -- Sect. III The Ocular motor system -- Sect. IV The Eyelid -- Sect. V Facial pain and headache -- Sect. VI Nonorganic disease -- V. II -- Sect. VII Tumors -- Sect. VIII The Phacomatoses -- Sect. IX Vascular disease -- V. III -- Sect. X Degenerative and metabolic diseases -- Sect. XI Infectious, inflammatory, and demyelinating diseases.
  • The first book to provide a systematic expert summary of normal white matter morphology as well as white matter injury following stroke and other CNS injuries. White matter injury can result from both ischemic and hemorrhagic stroke as well as a host of other CNS diseases and conditions such as neonatal injuries, neurodegenerative disorders including Alzheimer's disease, traumatic brain injuries, carbon monoxide poisoning, and drug or alcohol overdoses. The extent of white matter injury is extremely important to patient outcomes. Several recent technological developments including advanced neuroimaging and the breeding of new rodent models of white matter injury have provided growing insight into initial damage and repair after a stroke or other damaging event.
  • Astrocytic Tumours -- Oligodendroglial Tumours -- Ependymal Tumours -- Choroid Plexus Tumours -- Other Neuroepithelial Tumours -- Neuronal and Mixed Neuronal- Glial Tumours -- Tumours of the Pineal Region -- Embryonal Tumours -- Tumours of the Cranial and Paraspinal Nerves -- Meningeal Tumours -- Tumours of the Haematopoietic System -- Germ Cell Tumours -- Familial Tumour Syndromes involving the Nervous System -- Tumours of the Sellar Region --Metastatic Tumours of the CNS.
  • The term psychoneuroimmunology was originally coined to acknowledge the existence of functional interactions between the brain, the immune system and the endocrine system. As our understanding deepens regarding the interplay between the brain and the way bodies function, the field continues to grow in importance.
  • The controversial seat of myself -- A simple architecture of the brain -- Seeing through oneself : brain imaging -- Dispersed memories -- The prevention of Parkinson Disease -- The treatment of Alzheimer Disease -- The cerebrovascular accident -- The fatality of tumors -- Altered states of consciousness -- The myth of the artificial brain -- The power and the fragility of oneself.
  • Video-Aided Analysis of Zebrafish Locomotion and Anxiety-Related Behavioral Responses / Jonathan M. Cachat, Peter R. Canavello, Salem I. Elkhayat, Brett K. Bartels, Peter C. Hart, Marco F. Elegante, Esther C. Beeson, Autumn L. Laffoon, Whitlee A.M. Haymore, David H. Tien, Anna K. Tien, Sopan Mohnot, Allan V. Kalueff -- Videograms: A Method for Repeatable Unbiased Quantitative Behavioral Analysis Without Scoring or Tracking / Russell C. Wyeth, Oliver R. Braubach, Alan Fine, Roger P. Croll -- Automated Imaging of Avoidance Behavior in Larval Zebrafish / Ruth M. Colwill, Robbert Creton -- Quantifying Anti-predator Responses to Chemical Alarm Cues / Brian D. Wisenden -- Modified Associative Learning T-Maze Test for Zebrafish (Danio rerio) and Other Small Teleost Fish / Georgianna G. Gould -- Zebrafish Conditioned Place Preference Models of Drug Reinforcement and Relapse to Drug Seeking / Amit Parmar, Miral Parmar, Caroline H. Brennan -- A Simple and Effective Method to Condition Olfactory Behaviors in Groups of Zebrafish / Oliver R. Braubach, Russell C. Wyeth, Andrew Murray, Alan Fine, Roger P. Croll -- Aquatic Light/Dark Plus Maze Novel Environment for Assessing Anxious Versus Exploratory Behavior in Zebrafish (Danio rerio) and Other Small Teleost Fish / Georgianna G. Gould -- A Novel Test Battery to Assess Drug-Induced Changes in Zebrafish Social Behavior / David J. Echevarria, Christine Buske, Christina N. Toms, David J. Jouandot -- Measuring Agonistic Behavior in Zebrafish / Henning Schneider -- Measuring Endocrine (Cortisol) Responses of Zebrafish to Stress / Peter R. Canavello, Jonathan M. Cachat, Esther C. Beeson, Autumn L. Laffoon, Chelsea Grimes, Whitlee A.M. Haymore, Marco F. Elegante, Brett K. Bartels, Peter C. Hart, Salem I. Elkhayat, David H. Tien, Sopan Mohnot, Hakima Amri, Allan V. Kalueff -- Phenotyping of Zebrafish Homebase Behaviors in Novelty-Based Tests / Adam Stewart, Jonathan M. Cachat, Keith Wong, Nadine Wu, Leah Grossman, Christopher Suciu, Jason Goodspeed, Marco F. Elegante, Brett K. Bartels, Salem I. Elkhayat, David H. Tien, Siddharth Gaikwad, Ferdous Kadri, Kyung Min Chung, Julia Tan, Ashley Denmark, Thomas Gilder, John DiLeo, Katie Chang, Kevin Frank, Eli Utterback, Patrick Viviano, Allan V. Kalueff -- Neurophenotyping of Adult Zebrafish Using the Light/Dark Box Paradigm / Adam Stewart, Caio Maximino, Thiago Marques de Brito, Anderson Manoel Herculano, Amauri Gouveia, Silvio Morato, Jonathan M. Cachat, Siddharth Gaikwad, Marco F. Elegante, Peter C. Hart, Allan V. Kalueff -- Intraperitoneal Injection as a Method of Psychotropic Drug Delivery in Adult Zebrafish / Adam Stewart, Jonathan M. Cachat, Christopher Suciu, Peter C. Hart, Siddharth Gaikwad, Eli Utterback, John DiLeo, Allan V. Kalueff -- Assessing the Maximum Predictive Validity for Neuropharmacological Anxiety Screening Assays Using Zebrafish / Amanda Linker, Adam Stewart, Siddharth Gaikwad, Jonathan M. Cachat, Marco F. Elegante, Allan V. Kalueff, Jason E. Warnick -- Deconstructing Adult Zebrafish Behavior with Swim Trace Visualizations / Jonathan M. Cachat, Adam Stewart, Eli Utterback, Evan Kyzar, Peter C. Hart, Dillon Carlos, Siddharth Gaikwad, Molly Hook, Kathryn Rhymes, Allan V. Kalueff.

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A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available. 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