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Neurology

  • 2014 Alzheimer's Disease Facts and Figures is a statistical resource for U.S. data related to Alzheimer's disease, the most common type of dementia, as well as other dementias. Background and context for interpretation of the data are contained in the Overview. This information includes definitions of the various types of dementia and a summary of current knowledge about Alzheimer's disease. Additional sections address prevalence, mortality and morbidity, caregiving and use and costs of care and services. The Special Report discusses women and Alzheimer's disease.
  • The inaugural publication of the 7.0 Tesla MRI Brain Atlas: In-vivo Atlas with Cryomacrotome Correlation in 2010 provided readers with a spectacular source of ultra-high resolution images revealing a wealth of details of the brainstem and midbrain structures. This second edition contributes additional knowledge gained as a result of technologic advances and recent research. To facilitate identification and comparison of brain structures and anatomy, a detailed coordination matrix is featured in each image. Updated axial, sagittal, and coronal images are also included. This state-of-the-art and user-friendly reference will provide researchers and clinicians with important new perspectives.
  • The introduction of techniques that permit visualization of the human nervous system is one of the foremost advances in neuroscience and brain-related research. Among the most recent significant developments in this respect are ultra-high field MRI and the image post-processing technique known as track density imaging (TDI). It is these techniques (including super-resolution TDI) which represent the two major components of 7.0 Tesla MRI ? Brain White Matter Atlas. This second edition of the atlas has been revised and updated to fully reflect current application of these technological advancements in order to visualize the nervous system and the brain with the finest resolution and sensitivity. Exquisitely detailed color images offer neuroscientists, neurologists, and neurosurgeons a superb resource that will be of value both for the purpose of research and for the treatment of common brain diseases such as Alzheimer's disease and multiple sclerosis.
  • The aim of this new edition is to present information about neurological disorders in a structured and succinct way, following a "trickle down" principle: beginning with overviews and then moving on to specific disease categories. The latter address clinical features (i.e., information accessed by history-taking and physical examination), investigations, differential diagnosis, treatment, and prognosis. Cross-references to the Online Mendelian Inheritance in Man (OMIM) database have been given where relevant. --Preface excerpt.
  • A Brief Introduction to the History of the β-Amyloid Protein (Aβ) of Alzheimer's Disease / David Small and Colin Barrow -- The Aβcentric Pathway of Alzheimer's Disease / Victor Villemagne, Roberto Cappai, Kevin Barnham, Robert Cherny, Carlos Opazo, Kathy Novakovic, Christopher Rowe and Colin Masters -- The Function of the Amyloid Precursor Protein Family / Roberto Cappai, B. Elise Needham and Giuseppe Ciccotosto -- The Involvement of Aβ in the Neuroinflammatory Response / Piet Eikelenboom, Willem van Gool, Annemieke Rozemuller, Wiep Scheper, Rob Veerhuis and Jeroen Hoozemans -- Amyloid β-Peptide(1-42), Oxidative Stress, and Alzheimer's Disease / D. Butterfield -- Amyloid Toxicity, Synaptic Dysfunction, and the Biochemistry of Neurodegeneration in Alzheimer's Disease / Judy Ng, Marie-Isabel Aguilar and David Small -- Aβ Variants and Their Impact on Amyloid Formation and Alzheimer's Disease Progression / Laszlo Otvos -- Copper Coordination by β-Amyloid and the Neuropathology of Alzheimer's Disease / Cyril Curtain and Kevin Barnham -- Cholesterol and Alzheimer's Disease / Joanna Cordy and Benjamin Wolozin -- Amyloid β-Peptide and Central Cholinergic Neurons: Involvement in Normal Brain Function and Alzheimer's Disease Pathology / Satyabrata Karn, Z. Wei, David MacTavish, Doreen Kabogo, Mee-Sook Song and Jack Jhamandas -- Physiologic and Neurotoxic Properties of Aβ Peptides / Gillian Gregory, Claire Shepherd and Glenda Halliday -- Impact of β-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models / Jürgen Götz, Della David and Lars Ittner -- Glial Cells and Aβ Peptides in Alzheimer's Disease Pathogenesis / Gilbert Siu, Peter Clifford, Mary Kosciuk, Venkat Venkataraman and Robert Nagele -- The Role of Presenilins in Aβ-Induced Cell Death in Alzheimer's Disease / Maria Ankarcrona -- Immunotherapeutic Approaches to Alzheimer's Disease / Josef Karkos -- Mouse Models of Alzheimer's Disease / Dwight German.
  • This book provides recommendations for evaluation and therapy in the area of acute pediatric neurology; these are presented didactically with frequent use of illustrations and algorithms. Chapters in the first part of the book discuss presenting symptoms of acute neurological conditions. The second part of the book covers major areas of acute pediatric neurology and each of these chapters has three key elements: description of presenting symptoms; recommended assessments; and recommended interventions. Acute Pediatric Neurology provides an accessible, clinically focused guide to assist physicians in the emergency ward or intensive care unit in decisions on diagnosis and therapeutic interventions in all major acute pediatric neurological diseases.
  • Print Material
  • Ch. 1. Approach to the patient with neurologic disease -- Ch. 2. Imaging, electrophysiologic, and laboratory techniques for neurologic diagnosis -- Ch. 3. Motor paralysis -- Ch. 5. Ataxia and disorders of cerebellar function -- Ch. 6. Tremor, myoclonus, focal dystonias, and tics -- Ch. 7. Disorders of stance and gait -- Ch. 10. Headache and other craniofacial pains -- Ch. 11. Pain i n the back, neck, and extreities -- Ch. 12. Disorders of smell and taste -- Ch. 13. Disturbances of vision -- Ch. 14. Disorders of ocular movement and pupillary function -- Ch. 15. Deafness, dizziness, and disorders of equilibrium -- Ch. 16. Epilepsy and other seizure disorders -- Ch. 17. Coma and related disorders of consciousness -- Ch. 18. Faintness and syncope -- Ch. 19. Sleep and its abnormalities -- Ch. 20. Delirium and other acute confusional states.
  • What is addiction neuroethics and why does it matter? -- Brain Imaging in Addiction -- Molecular Neuroscience and Genetics -- Treating Opioid Dependence with Opioids: Exploring the Ethics -- Addiction Neuroscience and Tobacco Control -- Emerging Neurobiological Treatments of Addiction: Ethical and Public Policy Considerations -- Technical, Ethical and Social Issues in the Bioprediction of Addiction Liability and Treatment Response -- Autonomy, Responsibility and the Oscillation of Preference -- Consent and Coercion in Addiction Treatment -- Toward a Lay Descriptive Account of Identity in Addiction Neuroethics -- The Impact of Changes in Neuroscience and Research Ethics on the Intellectual History of Addiction Research -- The Diction of Addiction at the Intersection of Law and Neuroscience -- Social Epistemology: Communicating Neuroscience -- Population Approaches to Alcohol, Tobacco and Drugs: Effectiveness, Ethics and Interplay with Addiction Neuroscience -- Legal Regulation of Addictive Substances and Addiction -- Investment and Vested Interests in Neuroscience Research of Addiction: Ethical Research Requires More than Informed Consent -- Private and Public Approaches to Addiction Treatment: Evidence and Beliefs.
  • Addressing unmet medical needs in RR-MS / Robert A. Bermel & Richard A. Rudick -- Current guidelines and standard treatments of RR-MS / R. Philip Kinkel & Augusto Miravalle -- Oral agents for the treatment of RR-MS / Douglas R. Jeffery -- Monoclonal antibodies / Jennifer Graves & Emmanuelle L. Waubant -- Other therapeutics in the pipeline and future directions / Yuval Karmon, Bijal K. Mehta & Bianca Weinstock-Guttman.
  • Adenosine and Metabolism--A Brief Historical Note / Bertil B. Fredholm -- Adenosine Metabolism, Adenosine Kinase, and Evolution / Jaoek Park and Radhey S. Gupta -- Adenosine and Energy Metabolism--Relationship to Brain Bioenergetics / Xuesong Chen, Liang Hui and Jonathan D. Geiger -- Adenosine and Autocrine Metabolic Regulation of Neuronal Activity / Masahito Kawamura Jr. and David N. Ruskin -- Physiologic and Metabolic Regulation of Adenosine: Mechanisms / Chris G. Dulla and Susan A. Masino -- The Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the Books / Stephanie zur Nedden, Alexander S. Doney and Bruno G. Frenguelli -- Downstream Pathways of Adenosine / Ana M. Sebastião, Sofia Cristóvão-Ferreira and Joaquim A. Ribeiro -- Astrocytic ATP Release / Dustin J. Hines and Philip G. Haydon -- Role of Striatal A2A Receptor Subpopulations in Neurological Disorders / Sergi Ferré, César Quiroz, Marco Orrú, Xavier Guitart and Seema Gulyani, et al. -- Sleep and Adenosine: Human Studies / Tarja Porkka-Heiskanen -- Adenosine and Other Purinergic Products in Circadian Timing / Christine Muheim and Steven A. Brown -- Adenosine in the Immune System / György Hask, Balázs Koscsó́ and Balázs Csóka -- The Bioenergetic Network of Adenosine in Hibernation, Sleep, and Thermoregulation / Kelly L. Drew and Tulasi R. Jinka -- Adenosine and Stroke / Felicita Pedata, Anna Maria Pugliese, Francesca Corti and Alessia Melani -- The Many Roles of Adenosine in Traumatic Brain Injury / Patrick M. Kochanek, Jonathan D. Verrier, Amy K. Wagner and Edwin K. Jackson -- Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitution After Spinal Cord Injury / Kwaku D. Nantwi -- Adenosine and Pain / Jana Sawynok -- Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson's Disease / Annalisa Pinna, Nicola Simola, Lucia Frau and Micaela Morelli -- Adenosine Receptors and Alzheimer's Disease / David Blum, Ursula Sandau, Cyril Laurent, Vânia Batalha and Antoine Leboucher, et al. -- Adenosine Receptors in Huntington's Disease / David Blum, Alberto Martire, Sylvie Burnouf, Bernard Sablonnière and Pierre Krystkowiak, et al. -- Adenosine and Multiple Sclerosis / Maria Victoria Sánchez-Gómez, Estibaliz González-Fernández, Rogelio O. Arellano and Carlos Matute -- Adenosinergic Perspectives on Schizophrenia: Opportunity for an Integrative Synthesis / Benjamin K. Yee, Philipp Singer and Detlev Boison -- The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation / John D. Salamone, Merce Correa, Patrick A. Randall, Eric J. Nunes and Marta Pardo, et al. -- Adenosine and Autism: Physiological Symptoms and Metabolic Opportunities / Julia Svedova, Inge-Marie Eigsti and Susan A. Masino -- Stress, Brain Adenosine Signaling, and Fatigue-Related Behavioral Processes / Traci N. Plumb, Sarah R. Sterlace, Kelly A. Cavanaugh and Thomas R. Minor -- Disruption of Adenosine Homeostasis in Epilepsy and Therapeutic Adenosine Augmentation / Detlev Boison -- Ketogenic Diet and Epilepsy: The Role of Adenosine / Jong M. Rho, Beth Zupec-Kania and Susan A. Masino -- Silk: A Biocompatible and Biodegradable Biopolymer for Therapeutic Adenosine Delivery / Eleanor M. Pritchard, Detlev Boison and David L. Kaplan -- Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy / Zsolt Kovács and Arpád Dobolyi.
  • Neuroscience, Neuropsychology, and Attention-Deficit Hyperactivity Disorder: ADHD as a Model of Brain-Behavior Relationships -- ADHD, Attention, and DSM Diagnosis: History and Context -- ADHD and Neuropsychological Nomenclature -- Diagnostic Systems and Etiological Models -- Neuropsychological Models of Attention and ADHD -- Broad-Based Neuropsychological Test Batteries and ADHD -- Preliminary Answers to the Question -- Dimensional Approaches for Evaluating Disorders: Research Domain Criteria -- The Neocortex, Regional Functional Specialization, and Cognitive Networks -- Large-Scale Brain Networks and Functional Connectivity -- The Ontogeny of Functional Brain Networks -- Large-Scale Brain Network Disturbances in ADHD -- The Selection Problem -- The Basal Ganglia -- The Basal Ganglia and Intention Programs -- The Basal Ganglia: Focused Attention and Learning Through Integrative Networks -- Reward Circuitry and the Basal Ganglia -- The Cerebellum -- The Modular Organization of the Cerebellum -- The Development of Motor Skills, Executive Functions, and a Relationship to ADHD: A Preliminary Review -- Revisiting Neuropsychological Testing and the Paradox of ADHD -- Neural Network Dynamics: How Large-Scale Brain Networks Interact -- Concluding Remarks.
  • 1. Introduction -- 2. Diagnostic assessment -- 3. Diagnostic instruments -- 4. Treatment -- 5. Treatment: coaching adults with ADHD -- 6. Setup and organization of a specialist department.
  • The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer's disease and Parkinson's disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume.
  • Advances in Alzheimer's disease management / Serge Gauthier & Pedro Rosa-Neto -- Genetics of Alzheimer's disease / Jayashree Viswanathan, Hilkka Soininen & Mikko Hiltunen -- Diagnosis of Alzheimer's disease / Pedro Rosa-Neto, Jared Rowley, Antoine Leuzy, Sara Mohades, Monica Shin, Marina T. Dauar & Serge Gauthier -- Available symptomatic antidementia drugs / Marie-Pierre Thibodeau & Fadi Massoud -- New drugs under development for Alzheimer's disease / Lezanne Ooi, Kirubakaran Shanmugam, Mili Patel, Rachel Debono & Gerald Münch -- Management of agitation and aggression : controversies and possible solutions / Clive Ballard & Anne Corbett -- Guidelines for the diagnosis and treatment of Alzheimer's disease / Serge Gauthier & Christopher J.S. Patterson -- Ethical and clinically humane end-of-life care for those living with dementia / Michael Gordon -- Index.
  • Advances in antiepileptic drug development / Philip N. Patsalos -- Current guidelines and standard treatments / Dieter Schmidt & G{uml}unter Kr{uml}amer -- Advances in screening models for identifying new antiepileptic drugs / Kinga K. Borowicz & Stanislaw J. Czuczwar -- New antiepileptic drugs : advances in pharmacokinetics, drug interaction and adverse effect profiles / Domenico Italiano & Edoardo Spina -- Antiepileptic drugs in clinical trials and future direction / Alberto Verrotti, Chiara Cirillo & Giulia Loiacono.
  • "Preface This book brings together a wide-ranging set of contributed articles that address emerging practices and future trends in cognitive engineering and neuroergonomics. Both aim to harmoniously integrate human operator and computational system, the former through a tighter cognitive fit and the latter a more effective neural fit with the system. The chapters in this book uncover novel discoveries and communicate new understanding and the most recent advances in the areas of workload and stress, activity theory, human error and risk, and neuroergonomic measures, as well as associated applications.-- Provided by publisher.
  • Within our knowledge, the series of the International Conference on Cognitive Neurodynamics (ICCN) is the only conference series dedicating to cognitive neurodynamics. This volume is the proceedings of the 2nd International Conference on Cognitive Neurodynamics held in 2009, which reviews the progress in this field since the 1st ICCN -2007. The topics include: Neural coding and realistic neural network dynamics, Neural population dynamics, Firing Oscillations and Patterns in Neuronal Networks, Brain imaging, EEG, MEG, Sensory and Motor Dynamics, Global cognitive function, Multi-scalar Neurodyn
  • This book contains the Proceedings of the 3rd International Conference on Cognitive Neurodynamics held in Japan, June 9-13, 2011. It reviews the progress in this field since the first ICCN in 2007. The participants were treated to an exciting and stimulating conference that left everyone with an enthusiastic vision for the future. The discussed topics in this book include: Neural coding and realistic neural network dynamics, Neural population dynamics, Firing Oscillations and Patterns in Neuronal Networks, Brain imaging, EEG, MEG, Sensory and Motor Dynamics, Global cognitive function, Multi-scalar Neurodynamics - from Physiology to Systems Theory, Neural computing, Emerging Technologies for Brain Computer Interfaces, Neural dynamics of brain disorders.
  • Pt. 1. Methodologies to measure cognition in natural medicine trials -- pt. 2. Vitamins and nutrients -- pt. 3. Essential fatty acids and neurocognition -- pt. 4. Herbal medicines, nutraceuticals and neurocognition.
  • Advances in neuroendocrine tumor management / Kjell Öberg -- Classification of digestive neuroendocrine neoplasm / Guido Rindi & Frediano Inzani -- Molecular profile and diagnosis / Christos Toumpanakis -- Surgical approach / Rossella Bettini & Massimo Falconi -- Somatostatin analogs / Wouter W. de Herder -- Combinational chemotherapy and radiotherapy / Emilio Bajetta, Emilio Bombardieri, Laura Catena, Monica Valente & Nadia Bianco -- Which therapy for which patient? / Kjell Öberg.
  • Physical implementation of the memristor at industrial scale sparked the interest from various disciplines, ranging from physics, nanotechnology, electrical engineering, neuroscience, to intelligent robotics. As any promising new technology, it has raised hopes and questions; it is an extremely challenging task to live up to the high expectations and to devise revolutionary and feasible future applications for memristive devices. The possibility of gathering prominent scientists in the heart of the Silicon Valley given by the 2011 International Joint Conference on Neural Networks held in San Jose, CA, has offered us the unique opportunity of organizing a series of special events on the present status and future perspectives in neuromorphic memristor science. This book presents a selection of the remarkable contributions given by the leaders of the field and it may serve as inspiration and future reference to all researchers that want to explore the extraordinary possibilities given by this revolutionary concept.
  • Advances in Parkinson's disease management / Joseph H. Friedman -- Etiology and overview / Witold Polanski -- Biomarkers of Parkinson's disease / Mauro Fasano & Tiziana Alberio -- Imaging Parkinson's disease / David J. Brooks -- Dopaminergic agents / Lawrence W. Elmer & Robert A. Hauser -- Combined dopaminergic and nondopaminergic therapies / Mary Ann Thenganatt & Cheryl H. Waters -- Future drug therapy / Makoto Naoi & Wakako Maruyama -- Drug therapies for neuropsychiatric and autonomic disturbances in patients with PD / Thomas Müller -- Surgical treatment for Parkinson's disease / Sumito Sato & Hideki Mochizuki -- Cell and gene transplantation for Parkinson's disease : from the clinic / Paul E. Greene -- Current evidence-based guidelines for the management of Parkinson's disease / Nicolas Phielipp & Janis Miyasaki -- Index.
  • Advances in animal models of relapse for addiction research / Friedbert Weiss -- Application of chronic extracellular recording method to studies of cocaine self-administration : method and progress / Laura L. Peoples, Alexai V. Kravitz, and Karine Guillem -- Neurochemistry of addiction : monitoring essential neurotransmitters of addiction / Stefan G. Sandberg and Paul A. Garris -- Alcohol craving and relapse prediction : imaging studies / Andreas Heinz ... [et al.] -- Integrating behavioral and molecular approaches in mouse : self-administration studies / Danielle L. Graham and David W. Self -- Neuroeconomics : implications for understanding the neurobiology of addiction / Michael L. Platt ... [et al.].
  • Advances in the pathogenesis and treatment of glioblastoma multiforme / Michael Prados -- Pathogenesis, molecular characteristics and prognostic factors for survival / Keith L. Ligon -- Standard treatment approaches for newly diagnosed glioblastoma / Soon-Tae Lee & Patrick Y. Wen -- Targeted therapeutic strategies for relapsed disease / John F. de Groot & Howard Colman -- Genes, viruses, toxins and vaccines as therapeutic modalities / Tal Shahar, Manish K. Aghi & Zvi Ram -- Drug delivery strategies for glioblastoma / Pin-Yuan Chen, Dali Yin, John Forsayeth & Krystof S. Bankiewicz -- Index.
  • "This new edition of Meningiomas proves a valuable contribution to the literature on the fascinating aspects of meningioma biology, diagnosis, and management"--Provided by publisher.
  • "Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism"--Publisher's description.
  • This book is a comprehensive review of the main acquired disorders of reading: hemianopic, pure and central alexia. The authors review the diagnostic criteria for each of the different types of disorder, and the efficacy of the therapeutic studies that have attempted to remediate them. The different theoretical models of adult reading, which largely rest on how the reading system responds to injury, are also discussed and evaluated. Focal brain injury caused by stroke and brain tumors are discussed in depth as are the effects of dementia on reading. This book starts with a chapter on normal reading, followed by chapters on hemianopic alexia, pure alexia and central alexia, each structured in the same way, with: a description of the condition; a historical review of cases to date; psychophysics; consideration of the causative lesions; evidence from functional imaging studies on patients and, most importantly, a review of the evidence base for treating each condition. Finally, there is a chapter on how patient data has informed how we think about reading.
  • Relations between asthma and psychological distress: an old idea revisited -- Brain and asthma: what are the linkages? -- Stress-related programming of autonomic imbalance: role in allergy and asthma -- Role of parasympathetic nerves and muscarinic receptors in allergy and asthma -- Developmental programming of allergic diseases -- Mind-body interrelationship in DNA methylation -- Neurotrophins in chronic allergic airway inflammation and remodeling -- Pathways underlying afferent signaling of bronchopulmonary immune activation to the central nervous system -- Allergen-induced neuromodulation in the respiratory tract -- Role of microbiome in regulating the HPA axisd and its relevance to allergy -- Autonomic regulation of anti-inflammatory activities from salivary glands -- Mast cell-nerve functional unit: a key component of physiologic and pathophysiologic responses -- Neural and behavioral correlates of food allergy -- Neuroendocrine-immune connection regulates chronic inflammatory disease in allergy -- Itch and the brain.
  • Contemporary Approaches to Alzheimer's Disease and Frontotemporal Dementia / Erik D. Roberson -- Preparing Synthetic Aβ in Different Aggregation States / W. Blaine Stine, Lisa Jungbauer, Chunjiang Yu, Mary Jo LaDu -- Isolation of Low-n Amyloid β-Protein Oligomers from Cultured Cells, CSF, and Brain / Ganesh M. Shankar, Alfred T. Welzel, Jessica M. McDonald, Dennis J. Selkoe, Dominic M. Walsh -- Detecting Aβ*56 Oligomers in Brain Tissues / Mathew A. Sherman, Sylvain E. Lesné -- Assessing Aβ Aggregation State by Atomic Force Microscopy / Justin Legleiter -- Measuring APP Carboxy-Terminal Fragments / Luke A. Esposito -- Detection of APP Intracellular Domain in Brain Tissue / Sanjay W. Pimplikar, Anupama Suryanarayana -- Cell-Based Assays for Regulators of Tau Biology / Umesh K. Jinwal, Chad A. Dickey -- Split GFP Complementation Assay for Quantitative Measurement of Tau Aggregation In Situ / Wanjoo Chun, Geoffrey S. Waldo, Gail V. Johnson -- Apolipoprotein E Expression and Purification / Yvonne Newhouse, Karl H. Weisgraber -- Aβ Toxicity in Primary Cultured Neurons / Adriana Ferreira, Roxana C. Sinjoanu, Alexandra Nicholson, Sara Kleinschmidt -- Manipulation of Gene Expression in the Central Nervous System with Lentiviral Vectors / Binggui Sun, Li Gan -- Selecting a Mouse Model of Alzheimer's Disease / Jeannie Chin -- Monitoring Spatial Learning and Memory in Alzheimer's Disease Mouse Models Using the Morris Water Maze / Kimberly Scearce-Levie -- Step-by-Step In Situ Hybridization Method for Localizing Gene Expression Changes in the Brain / Jorge J. Palop, Erik D. Roberson, Inma Cobos -- Real-Time Visualization of Axonal Transport in Neurons / Yasuko Osakada, Bianxiao Cui -- Quantifying Biomarkers of Cognitive Dysfunction and Neuronal Network Hyperexcitability in Mouse Models of Alzheimer's Disease: Depletion of Calcium-Dependent Proteins and Inhibitory Hippocampal Remodeling / Jorge J. Palop, Lennart Mucke, Erik D. Roberson -- Epigenetic Changes in the Brain: Measuring Global Histone Modifications / Gavin Rumbaugh, Courtney A. Miller.
  • The global impact of Alzheimer's disease / M.C. Carrillo, W. Thies, L.J. Bain -- The genetics of Alzheimer's disease / M.C. Schu ... [et al.] -- Current conceptual view of Alzheimer's disease / K. Herrup -- Neuropathological basis of Alzheimer's disease and Alzheimer's disease diagnosis / J.A. Schneider ... [et al.] -- Diagnostic tools : fluid biomarkers for Alzheimer's disease / H. Zetterberg, H. Hampel, K. Blennow -- MRI-and PET-based imaging markers for the diagnosis of Alzheimer's disease / S. Teipel ... [et al.] -- Changing diagnostic concepts of Alzheimer's disease / G.M. McKhann, M.S. Albert, R.A. Sperling -- Pharmacological treatment of Alzheimer's disease / L.S. Schneider -- Regulatory requirements on clinical trials in Alzheimer's disease / K. Broich ... [et al.] -- Perspectives on Alzheimer's disease : past, present and future / Z.S. Khachaturian.
  • 2012 ClinicalKey
    The emergence of electrophysiology as an aid to neurology / Mary A.B. Brazier -- Electrophysiologic equipment and electrcial safety / John A. Cadwell and Richard A. Villarreal -- Electroencephalography and magnetoencephalography. Electroencephalography: general principles and clinical applications / Michael J. Aminoff -- Neonatal and pediatric electroencephalography / Jin S. Hahn -- Electroencephalographic artifacts and benign variants / Jeffrey W. Britton -- Video-EEG monitoring for epilepsy / John M. Stern and Jerome Engel, Jr. -- Invasive clinical neurophysiology in epilepsy and movement disorders / William J. Marks, Jr and Kenneth D. Laxer -- Topographic mapping, frequency analysis, and other quantitative techniques in electroencephalography / Marc R. Nuwer and Pedro Coutin-Churchman -- Intraoperative electroencephalographic monitoring during carotid endarterectomy and cardiac surgery / Gregory D. Cascino and Frank W. Sharbrough, III -- Magnetoencephalography / William W. Sutherling -- Electromyography, nerve conduction studies, and related techniques. Clinical electromyography / Michael J. Aminoff -- Quantitative electromyography / Mark B. Bromberg -- Nerve conduction studies / Jasper R. Daube and Devon I. Rubin -- Microneurography and its potential clinical applications / David Burke -- Nerve excitability: a clinical translation / Matthew C. Kiernan and Cindy Shin Yi Lin -- Neuromuscular ultrasound as a complement to the electrodiagnostic evaluation / Francis O. Walker and Michael S. Cartwright -- Electrophysiologic study of disorders of neuuromuscular transmission / Donald B. Sanders -- H-reflex and F-response studies / Morris A. Fisher -- The blink reflex and other cranial nerve reflexes / Josep Valls-Sole -- Electrophysiologic evaluation of movement disorders / Mark Hallett -- Evaluation of the autonomic nervous system / Michael J. Aminoff -- Evoked potentials and related techniques. Visual evoked potentials, electroretinography, and other diagnostic approaches to the visual system / Ari J. Green -- Visual evoked potentials in infants and children / Eileen E. Birch and Vidhya Subramanian -- Brainstem auditory evoked potentials: methodology, interpretation, and clinical application / Alan D. Legatt -- Brainstem auditory evoked potentials in infants and children / Terence W. Picton, margot J. Taylor, and Andree Durieux-Smith -- Somatosensory evoked potentials / Michael J. Aminoff and Andrew Eisen -- Somatosensory evoked potentials in infants and children / Michael J. Aminoff -- Diagnostic and therapeutic role of magnetic stimulation in neurologuy / Robert Chen and Nicolae Petrescu -- Event-related potentials / Douglas S. Goodin -- Intraoperative monitoring by evoked potential techniques / Ronald G. Emerson and David C. Adams -- Bladder, bowel, and sexual dysfunction. electrophysiologic evaluation of sacral function / Simon Podnar and David B. Vodusek -- Tests of vestibular function. Vestibular laboratory testing / Joseph M. Furman and Floris L. Wuyts -- Electrophysiologic evaluation in special situations. Polysomnographic evaluation fo sleep disroders / Vivien C. Abad and Christian Guilleminault -- Electrophysiologic evaluation of patients in the intensive care unit / G. Bryan Young and Charles F. Bolton -- Electrophysiologic evaluation of brain death: a critical appraisal / Thomas P. Bleck -- Electrophysiologic techniques in the evaluation of patients with suspected neurotoxic disorders / Michael J. Aminoff and James W. Albers.
  • Aminoff's Neurology and General Medicine is the standard and classic reference providing comprehensive coverage of the relationship between neurological practice and general medicine. As neurologists are asked to consult on general medical conditions, this reference provides an authoritative tool linking general medical conditions to specific neurological issues and disorders. This is also a valuable tool for the general practitioner seeking to understand the neurological aspects of their medical practice. Completely revised with new chapters covering metastatic disease, bladder disease, psychogenic disorders, dementia, and pre-operative and post-operative care of patients with neurologic disorders, this new edition will again be the go-to reference for both neurologists and general practitioners.
  • Since information in the brain is processed by the exchange of spikes among neurons, a study of such group dynamics is extremely important in understanding hippocampus dependent memory. These spike patterns and local field potentials (LFPs) have been analyzed by various statistical methods. These studies have led to important findings of memory information processing. For example, memory-trace replay, a reactivation of behaviorally induced neural patterns during subsequent sleep, has been suggested to play an important role in memory consolidation. It has also been suggested that a ripple/sharp wave event (one of the characteristics of LFPs in the hippocampus) and spiking activity in the cortex have a specific relationship that may facilitate the consolidation of hippocampal dependent memory from the hippocampus to the cortex. The book will provide a state-of-the-art finding of memory information processing through the analysis of multi-neuronal data. The first half of the book is devoted to this analysis aspect. Understanding memory information representation and its consolidation, however, cannot be achieved only by analyzing the data. It is extremely important to construct a computational model to seek an underlying mathematical principle. In other words, an entire picture of hippocampus dependent memory system would be elucidated through close collaboration among experiments, data analysis, and computational modeling. Not only does computational modeling benefit the data analysis of multi-electrode recordings, but it also provides useful insight for future experiments and analyses. The second half of the book will be devoted to the computational modeling of hippocampus-dependent memory.
  • Part I: Basic Spike Train Statistics -- 1 Stochastic Models of Spike Trains -- 2 Estimating the Firing Rate -- 3 Analysis and Interpretation of Interval and Count Variability in Neural Spike Trains -- 4 Processing of Phase-Locked Spikes and Periodic Signals -- Part II: Pairwise Comparison of Spike Trains -- 5 Pair-Correlation in the Time and Frequency Domain -- 6 Dependence of Spike-Count Correlations on Spike-Train Statistics and Observation Time Scale -- 7 Spike Metrics -- 8 Gravitational Clustering -- Part III: Multiple-Neuron Spike Patterns -- 9 Spatio-Temporal Patterns -- 10 Unitary Event Analysis -- 11 Information Geometry of Multiple Spike Trains -- 12 Higher-Order Correlations and Cumulants -- Part IV: Population-Based Approaches -- 13 Information Theory and Systems Neuroscience -- 14 Population Coding -- 15 Stochastic Models for Multivariate Neural Point Processes: Collective Dynamics and Neural Decoding -- Part V: Practical Issues -- 16 Simulation of Stochastic Point Processes with Defined Properties -- 17 Generation and Selection of Surrogate Methods for Correlation Analysis -- 18 Bootstrap Tests of Hypotheses -- 19 Generating Random Numbers -- 20 Practically Trivial Parallel Data Processing in a Neuroscience Laboratory -- Index.
  • Development and developmental disorders -- Neuroembryology -- Regional anatomy and related syndromes -- Peripheral nerves -- Plexuses -- Nerve roots and spinal nerves -- Spinal cord -- Brainstem -- Cranial nerves -- Cerebellum -- Thalamus -- Hypothalamus -- Basal ganglia -- Limbic system -- Cerebral cortex -- System-based anatomy and differential diagnosis -- Somatosensory system -- Visual system -- Auditory system -- Ocular motor system -- Motor system -- Autonomic nervous system -- Consciousness -- Fluid-system anatomy and function -- Vascular system -- Cerebrospinal fluid.
  • This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.
  • Conceptual Issues -- The Different Facets of Anhedonia and Their Associations with Different Psychopathologies -- Understanding Anhedonia: The Role of Perceived Control -- Circadian Fluctuation of Reward Response and Synchronization to Reward -- Anhedonia in Children and Adolescents -- Musical Anhedonia and Visual Hypoemotionality: Selective Loss of Emotional Experience in Music and Vision -- Projecting Oneself into the Future, an Intervention for Improving Pleasure in Patients with Anhedonia -- Neurobiological Advances -- Translational Models of Dopaminergic Mechanisms for Motivational Deficits in Anhedonic Patients -- Brain Systems for the Pleasure of Food and Other Primary Rewards -- Neurogenetics and Neurobiology of Dopamine in Anhedonia -- The Neuroendocrinology of Anhedonia -- Electrophysiological Signatures of Reward Processing in Anhedonia -- Anhedonia in Mouse Models of Methamphetamine-Induced Drug Seeking Behavior -- Neural Basis of Anhedonia Associated with Stress-Induced Eating Disorders -- Brain Imaging Correlates of Anhedonia.
  • Anhedonia in Psychotic Disorders -- Anhedonia in Schizophrenia: A Brief History and Overview of the Construct -- Measuring Anhedonia in Schizophrenia-Spectrum Disorders: A Selective Update -- Hedonic Capacity and Related Factors in Schizophrenia and Schizoaffective Disorder -- Anhedonia as an Indicator of Genetic Vulnerability to Schizophrenia -- Anhedonia in Schizophrenia: A Deficit in Translating Reward Information into Motivated Behavior -- Anhedonia in Mood and Personality Disorders -- Neural Correlates of Anhedonia as a Trait Marker for Depression -- Anhedonia in Trauma Related Disorders: The Good, the Bad, and the Shut-Down -- Anhedonia and Anorexia Nervosa: A Neurocognitive Perspective -- Anhedonia and Negative Symptom Schizotypy -- Anticipatory and Consummatory Anhedonia in Individuals with Schizotypal Traits -- Anhedonia and Risk of Suicide: An Overview -- Anhedonia in Neurological and Physical Disorders -- Anhedonia and Epilepsy -- Anhedonia in Parkinson's Disease and Other Movement Disorders -- Anhedonia in Heart Disease -- Cerebrovascular Diseases: Post-stroke Depression and Anhedonia.
  • Animal models of dementia 2011
    Springer Protocols
    General introduction to animal models of human conditions / Peter Paul De Deyn and Debby Van Dam -- Animal models of dementia : ethical considerations / I. Anna S. Olsson and Peter Sandøe -- The role of rodent models in the drug discovery pipeline for dementia / Debby Van Dam and Peter Paul De Deyn -- Species, strain, and gender issues in the development and validation of animal models of dementia / Annemie Van Dijck, Debby Van Dam, and Peter Paul De Deyn -- Transgenic and gene targeted models of dementia / Ronald A. Conlon -- Transgenic animals and intellectual property concerns / Susan L. Stoddard and James A. Rogers III -- Pathological validation of animal models of dementia / Daniel Pirici, Christine Van Broeckhoven, and Samir Kumar-Singh -- Behavioral validation in animal models of dementia / Debby Van Dam, Annemie Van Dijck, and Peter Paul De Deyn -- Pharmacological validation in animal models of dementia / Hugo Geerts -- Validation of animal models of dementia : neurochemical aspects / Giancarlo Pepeu and Maria Cristina Rosi -- Validation of dementia models employing neuroimaging techniques / Greet Vanhoutte, Adriaan Campo, and Annemie Van der Linden -- Drosophila melanogaster as a model organism for dementia / Maria E. Giannakou and Damian C. Crowther -- Caenorhabditis elegans as a model organism for dementia / Tjakko J. Van Ham and Ellen A.A. Nollen -- Zebrafish (Danio rerio) as a model organism for dementia / Rob Willemsen ... [et al.] -- Spontaneous vertebrate models of Alzheimer dementia : selectively bred strains (SAM strains) / Renã A. Sowell and D. Allan Butterfield -- Lesion-induced vertebrate models of Alzheimer dementia / Adolfo Toledano and Maria Isabel Álvarez -- A[Beta] infusion and related models of Alzheimer dementia / Patricia A. Lawlor and Deborah Young -- APP-based transgenic models : the PDAPP model / Jacob M. Basak and David M. Holtzman -- APP-based transgenic models : the Tg2576 model / Robert M.J. Deacon -- APP-based transgenic models : the APP23 model / Debby Van Dam and Peter Paul De Deyn -- Presenilin-based transgenic models of Alzheimer's dementia / Yuji Yoshiike and Akihiko Takashima -- APOE-based models of "pre-dementia" / Patrick M. Sullivan -- TAU models / Nicolas Sergeant and Luc Buée -- The 3xTg-AD mouse model : reproducing and modulating plaque and tangle pathology / Michael Sy, Masashi Kitazawa, and Frank LaFerla -- Cognitive dysfunction in genetic mouse models of parkinsonism / Sheila M. Fleming, J. David Jentsch, and Marie-Françoise Chesselet -- Mouse models of metachromatic leukodystrophy and adrenoleukodystrophy / Patrick Aubourg, Caroline Sevin, and Nathatie Cartier -- Animal models of amyotrophic lateral sclerosis / Ludo Van Den Bosch -- Animal models of frontotemporal dementia / Hana N. Dawson and Daniel T. Laskowitz -- CADASIL : molecular mechanisms and animal models / Karl J. Fryxell -- Spontaneously hypertensive rat (SHR) : an animal model of vascular brain disorder / Francesco Amenta and Daniele Tomassoni -- Animal models of normal pressure hydrocephalus / Petra M. Klinge -- Animal models of traumatically-induced dementia / Jennifer E. Slemmer, Mohammad Z. Hossain, and John T. Weber -- Animal models of alcohol-induced dementia / Angela Maria Ribeiro and Silvia R. Castanheira Pereira -- Animal models of metallic dementia / Luigi F. Rodella.
  • Animal models of drug addiction 2011
    Springer Protocols
    Intracranial self-stimulation / Styliani Vlachou and Athina Markou -- Stimulant self-administration / Leigh V. Panlilio -- Opiate self-administration / Francesco Leri -- Nicotine self-administration / Robert E. Sorge and Paul B.S. Clarke -- Alcohol self-administration / Friedbert Weiss -- Place conditioning / Christopher L. Cunningham, Peter A. Groblewski, and Charlene M. Voorhees -- Sensitization / Jessica A. Loweth and Paul Vezina -- Animal models of eating disorders / Stephanie D. Hancock and Mary C. Olmstead -- Acquisition of drug self-administration / Marilyn E. Carroll and Richard A. Meisch -- Escalation of drug use / Serge H. Ahmed -- Environmental modulation of drug taking / Aldo Badiani ... [et al.] -- Craving / Jeffrey W. Grimm -- Habit formation and compulsion / David Belin ... [et al.] -- Impulsivity / Andrea Bari, Trevor W. Robbins, and Jeffrey W. Dalley -- Binge drug taking / Herbert E. Covington, III and Klaus A. Miczek -- Withdrawal / Alasdair M. Barr, Heidi N. Boyda, and Ric M. Procyshyn -- Relapse / Suzanne Erb and Franca Placenza.
  • The nematode, Caenorhabditis elegans, as an emerging model for investigating epilepsy / Cody J. Locke, Kim A. Caldwell, and Guy A. Caldwell -- The genetics and molecular biology of seizure susceptibility in drosophila / Juan Song and Mark A. Tanouye -- The albino Xenopus laevis tadpole as a novel model of developmental seizures / D. Sesath Hewapathirane and Kurt Haas -- Zebrafish as a simple vertebrate organism for epilepsy research / Scott C. Baraban -- Modeling tuberous sclerosis complex: brain development and hyperexcitability / Devin C. Ess -- BK potassium channel mutations affecting neuronal function and epilepsy / David Petrik, Qing H. Chen, and Robert Brenner -- Mouse models of benign familial neonatal convulsions (BFNC): mutations in KCNQ (Kv7)genes / Nanda A. Singh ... [et al.] -- Interneuron loss as a cause of seizures: lessons from interneuron-deficient mice / Dorothy Jones-Davis, Maria-Elisa Calcagnotto, and Joy Y. Sebe -- Imaging seizure propagation in vitro / Andrew J. Trevelyan and Rafael Yuste -- Complexity untangled: large-scale realistic computational models in epilepsy / Robert J. Morgan and Ivan Soltesz -- Organotypic hippocampal slice cultures as a model of limbic epileptogenesis / Suzanne B. Bausch -- Seizure analysis and detection in vivo / Javier Echauz, Stephen Wong, and Brian Litt -- Viral vector gene therapy for epilepsy / Stacey B. Foti, Shelley J. Russek, Amy R. Brooks-Kayal, and Thomas J. McCown -- Neural stem cells in experimental mesial temporal lobe epilepsy / Michelle M. Kron and Jack M. Parent.
  • Animal Models of Speech and Language Disorders is arguably the first book that integrates several decades of research on the neuroscience and genetics of speech and language with behavioral, systems, cellular and molecular neurobiological studies on animal communication to create a synthesis of ideas with potential translational value in neurology, neurolinguistics and speech science. Speech and language dysfunctions plague a large segment of todays young and old alike because, besides being primary afflictions, they are also an integral part of the complex symptomatology of most of the common neurological and neurodevelopmental disorders, such as stroke, dementia, intellectual disability and autism. It is therefore essential that biomedical research be focused on understanding their neurobiological and genetic bases in order to have the chance of developing rational approaches to treating them. By weaving together findings from diverse disciplines in the comparative biology of vocal communication in songbirds, bats, New World monkeys and the great apes, with the applied and translational perspective in mind, this book attempts to create awareness among researchers and students about the strengths of the comparative and evolutionary approach to the scientific understanding of speech and language, and to addressing intractable clinical problems affecting higher brain functions. Animal Models of Speech and Language Disorders will be highly instructive to researchers, clinicians, advanced speech pathology and neuroscience students, and all those who are interested in the current state of knowledge in the basic and applied aspects of speech and language.
  • Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs. Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.
  • Evaluation and decision making for metastatic spine tumors / Yan Michael Li, Michael S. Dirks, Claudio E. Tatsui, and Laurence D. Rhines -- Neoplastic spinal instability / Daryl R. Fourney and Charles G. Fisher -- Major complications associated with stereotactic ablative radiotherapy (SABR) for spinal metastasis / Simon S. Lo, Arjun Sahgal, and Eric L. Chang -- En bloc resection in the treatment of spinal metastases : technique and indications / Ilya Laufer, Jean-Paul Wolinksy, and Mark H. Bilsky -- Region specific approaches / Daniel Sciubba -- Spinal reconstruction and fixation/fusion / Rajiv Saigal and Dean Chou -- Minimally invasive surgery for metastatic spine disease / Meic H. Schmidt -- Vertebral augmentation for metastatic disease / Ehud Mendel, Eric Bourekas, and Paul Porensky -- Surgical complications and avoidance / Michelle J. Clarke.
  • Evaluation and decision making / Stefano Boriani and Charles Fisher -- Safety and efficacy of surgery for primary tumors of the spine / Daryl R. Fourney, Charles Fisher, and Stefano Boriani -- Interventional options for primary tumors / Sudhir Kathuria -- Radiation therapy for primary bone tumors / Brent Y. Kimball and Yoshiya Yamada -- Medical oncology principles for the spine oncology surgeon / Scott H. Okuno, Steven Robinson and Shreyaskumar Patel -- Spinal osteoid osteoma and osteoblastoma / Melissa Nadeau and Christian DiPaola -- ABC, giant cell / Stefano Boriani, Stefano Bandiera, Riccardo Ghermandi, Simone Colangeli, Luca Amendola, and Alessandro Gasbarrini -- Chordoma / Jackson Sui, Patricia L. Zadnik, Mari L. Groves, and Ziya L. Gokaslan -- Chondrosarcoma / Stefano Boriani, Stefano Bandiera, Riccardo Ghermandi, Simone Colangeli, Luca Amendola, and Alessandro Gasbarrini -- Osteogenic and ewing sarcomas of the spine / Derek G. Ju, Patricia L. Zadnik, and Daniel M. Sciubba -- Margins in spine tumor resection : how much is enough? is planned -- Transgression okay? / Ilya Laufer, Mari Groves, and Jean-Paul Wolinsky -- Principles behind determining the right approach / Nicolas Dea and Rowan Schouten -- Spino-pelvic reconstruction/fixation and fusion / Peter Paul Varga -- Structural graft selection and wound closure techniques -- Complications and avoidance: how to plan primary tumor resection to minimize complications and maximize outcome / Michael C. Oh, Vedat Deviren, and Christopher P. Ames.
  • Culling together excerpts from a wide range of writings by Dr. Kewal K. Jain on biotechnology topics as they relate to disorders of the nervous system, Applications of Biotechnology in Neurology covers a variety of applications for those working in life sciences and the pharmaceutical sciences, particularly those developing diagnostics and therapeutics for the nervous system. This detailed volume delves into areas such as neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, various methods of improving systemic administration of drugs for targeted delivery to the nervous system, including the use of nanobiotechnology, biotechnology-based strategies and products for neuroprotection, as well as chapters on neurosurgery and personalized neurology.
  • Single channel theory and automaticity theory -- Attention control -- Visual attention control, scanning & information sampling -- Visual search -- Spatial attention and displays -- Resources and effort -- Time sharing and multiple resource theory -- Executive control: attention switching, interruptions, and task-management -- Individual differences in attention -- Cognitive neurosciences and neuroergonomics.
  • Ataxic disorders 2012
    ScienceDirect
  • Atlas of Brain and Spine Oncology Imaging presents a comprehensive visual review of pathologic disease variations of cancers of the brain and spine through extensive radiologic images. The focus of the book is on algorithmic strategies for identifying neoplastic pathologies commonly found in brain and spinal tumors through a visual representation of the variety of appearances that each neoplasm takes, within both benign and malignant manifestations.
  • Developmental disorders / Suresh Kotagal ... [et al.] -- Genetic diseases of the nervous system / Thomas D. Bird and Suman Jayadev -- Neuroendocrine disorders / Earl A. Zimmerman -- Critical care neurology / Marek A. Mirski ... [et al.] -- Cerebrovascular disease / David M. Greer ... [et al.] -- Dementias / Thomas J. Grabowski Jr. -- Behavioral neurology / Daniel Tranel and Thomas J. Grabowski, Jr. -- Neuro-oncology / Karen L. Fink and Elisabeth J. Rushing -- Movement disorders / Stanley Fahn ... [et al.] -- The epilepsies / Paul C. Van Ness -- Neuromuscular disease / Gil I. Wolfe ... [et al.] -- Infectious diseases of the nervous system / Burk Jubelt -- Neuroimmunology / Michael R. Swenson -- Neurotoxic disorders / Leon Prockop, Charles Brock, and Peter S. Spencer -- Headache / Marc E. Lenaerts.
  • Neurological investigation -- Motor neurone and peripheral nerve diseases -- Myopathies and myasthenia -- Cerebrovascular disease : cerebral infarction -- Cerebral haemorrhage and other cerebrovascular disorders -- Dementia syndromes -- Extra pyramidal disorders -- Intracranial tumours : paraneoplastic (non-metastatic) neurological syndromes -- Spinal tumours and paraneoplastic disorders -- Developmental and familial disorders -- Pain syndromes and trauma -- Infections -- Multiple sclerosis and other demyelinating disorders -- Spinal disorders -- Cranial neuropathies -- Neurological aspects of systemic disease -- Epilepsy.
  • Normal Sleep Stages -- Normal Electroencephalography Variants in Sleep -- Nonepileptiform Abnormalities -- Epileptiform Abnormalities -- Artifacts.
  • Atlas of epilepsies 2010
    Springer
  • Surface Anatomy of the Brain -- Sectional Anatomy of the Fetal Brain -- Sectional Anatomy of the Postnatal Brain.
  • Introduction. Headache disorders -- Epidemiology and burden -- Barriers to care -- Purpose of the atlas of headache disorders -- Methods. Questionnaire development -- Identification of respondents -- Data collection -- Data management and analysis -- Results. Data quality. Representativeness -- Limitations -- Data organization and presentation -- Themes. Epidemiology -- Impact on society, and national data -- Health-care utilization -- Diagnosis and assessment -- Treatment -- Professional training -- National professional organizations -- Issues -- The way forward.
  • v. 2, 2003 CRCnetBASE
    v. 3, 2005 CRCnetBASE
    v. 4, 2006 CRCnetBASE
    v. 5, 2008 CRCnetBASE
    v. 1. The spinal cord from gestational week 4 to the fourth postnatal month -- v. 2. The human brain during the third trimester -- v. 3. The brain during the second trimester -- v. 4. The brain during the late first trimester -- v. 5. The brain during the early first trimester.
  • 1. Tools -- 2. Principles of Peripheral Nerve Surgery -- 3. Principles of Nerve and Muscle Rehabilitation -- 4. Chronic Pain in Neuromuscular Disease -- 5. Cranial Nerve -- 6. Radiculopathies -- 7. Plexopathies -- 8. Mononeuropathies -- 9. Polyneuropathies -- 10. Neuromuscular Transmission: Endplate Disorders -- 11. Muscle and Myotonic Diseases -- 12. Motor Neuron Diseases -- 13. Autonomic Nervous System -- General Disease Finder.
  • In recent years, sonography of the peripheral nervous system has gained widespread acceptance. New diagnostic applications have emerged, and the field of ultrasound-guided interventions has expanded significantly: regional anesthesia, peripheral nerve blocks, and similar techniques are now frequently performed under ultrasound guidance by anesthesiologists and pain physicians alike. This atlas of peripheral nerve ultrasound is designed to meet the daily needs of both radiologists and clinicians by allowing rapid review of typical features, knowledge of which is important for successful diagnosis and intervention.
  • The number of surgical procedures performed on the brain, head, neck, and spine has increased markedly in recent decades. As a result, postoperative changes are being encountered more frequently on neuroradiological examinations and constitute an important part of the workflow. However, the imaging correlates of postsurgical changes can be unfamiliar to neuroradiologists and neurosurgeons and are sometimes difficult to interpret. This book is written by experts in the field and contains an abundance of high-quality images and concise descriptions, which should serve as a useful guide to postsurgical neuroradiology. It will familiarize the reader with the various types of surgical procedure, implanted hardware, and complications. Indeed, this work represents the first text dedicated to the realm of postoperative neuroimaging. Topics reviewed include imaging after facial cosmetic surgery; orbital and oculoplastic surgery; sinus surgery; scalp and cranial surgery; brain tumor treatment; psychosurgery, neurodegenerative surgery, and epilepsy surgery; skull base surgery including transsphenoidal pituitary resection; temporal bone surgery including various ossicular prostheses; orthognathic surgery; surgery of the neck including the types of dissection and flap reconstruction; CSF diversion procedures and devices; spine surgery; and vascular and endovascular neurosurgery.
  • 1. The Quest -- 2. Thinking About Thinking -- 3. Kinds of Thought -- 4. Carriers and Repositories of Thought -- 5. Examples of Specific Ways of Thinking -- 6. Global Interactions -- 7. On the Nature of Consciousness -- 8. Theories of Consciousness -- 9. Conclusions.
  • Attention-deficit hyperactivity disorder in adults : an overview / P.H. Wender, D.A. Tomb -- Family and twin studies in attention-deficit hyperactivity disorder / C.M. Freitag, W. Retz -- Molecular genetics of attention-deficit hyperactivity disorder / W. Retz, C.M. Freitag -- Neurophysiology of adult attention-deficit hyperactivity disorder / C.G. Baehne, A.J. Fallgatter -- Brain imaging in adult attention-deficit hyperactivity disorder / M. Schneider, M. Rösler, W. Retz -- Attention-deficit/hyperactivity disorder in adults : diagnosis and prevalence / R.-D. Stieglitz -- Comorbidity in adult attention-deficit hyperactivity disorder / R.G. Klein, S. Mannuzza -- Adult attention-deficit hyperactivity disorder : functional impairment, conduct problems, and criminality / M. Rösler -- Psychotherapy in adult attention-deficit hyperactivity disorder / A. Philipsen ... [et al.] -- Psychopharmacological treatment of attention-deficit hyperactivity disorder in adults / G.-E. Trott.
  • Historical aspects of attention deficit hyperactivity disorder / Roscoe A. Dykman -- Scanning the genome for attention deficit hyperactivity disorder / Aiveen Kirley -- Dopamine knockouts and behavior / Davide Viggiano, Daniela Vallone, Lucia A. Ruocco, and Adolfo G. Sadile -- The SHR as a model of attention deficit hyperactivity disorder / Vivienne Ann Russell -- The roles of Norepinephrine and Serotonin in attention deficit hyperactivity disorder / Roberd D. Oades -- Intermittent hypoxia during sleep as a model of environmental (nongenetic) contributions to attention deficit hyperactivity disorder / Barry W. Row and David Gozal -- The psychological evaluation of attention deficit hyperactivity disorder in school-aged children: a clinical approach based on recent practice guidelines / Dean W. Beebe -- Executive function / Martha Bridge Denckla -- The neuropsychology of attention deficit hyperactivity disorder: validity of the executive function hypothesis / Eric G. Willcutt, Kimberly Brodsky, Nomita Chhabildas, Michelle Shanahan [et al.] -- Attention deficit hyperactivity disorder and learning disabilities / Stephen R. Hooper and Emily A. Williams -- Selective attention deficits in children with attention deficit hyperactivity disorder: a review of behavioral and electrophysiological studies / Lisa M. Jonkman -- Working memory in children with attention deficit hyperactivity disorder / Jack Stevens -- Developmental underpinnings of the association of attention deficit hyperactivity disorder and its subtypes to neuropsychological and academic weaknesses / Tuija Aro, Margaret Semrud-Clikeman, Anne-Mari Lapvetelainen, and Heikki Lyytinen -- Social functioning of children with attention deficit hyperactivity disorder / Gaba Tur-Kaspa -- Reading disabilities in children with attention deficit hyperactivity disorder / Juliana S. Bloom, Carlin J. Miller, Mauricio A. Garcia, and George W. Hynd -- Attention deficit hyperactivity disorder and the brain: evidence from electrophysiological studies / Alexandra P. Fonaryova-Key, Melissa Ferguson, and Dennis L. Molfese -- Anatomical and functional neuroimaging studies of children and adolescents with attention deficit hyperactivity disorder / Jonathan C. Pfeifer, Melissa DelBello, and Scott Holland -- State regulation and attention deficit hyperactivity disorder / Jaap van der Meere -- Sleep and attention deficit hyperactivity disorder / Louise M. O'Brien and David Gozal -- Neurophysiological performance in adults with attention deficit hyperactivity disorder / Lisa Lee Weyandt -- Psychostimulants in attention deficit hyperactivity disorder: theoretical and practical issues for the community practitioner / Daniel F. Connor -- Pharmacokinetic and pharmacodynamic drug interactiions: methylphenidate, amphetamine or atomoxetine in attention deficit hyperactivity disorder / John S. Markowitz and Kennerly S. Patrick.
  • This book provides an overview of attentional impairments in brain-damaged patients from both clinical and neuroscientific perspectives, and aims to offer a comprehensive, succinct treatment of these topics useful to both clinicians and scholars. A main focus of the book concerns left visual neglect, a dramatic but often overlooked consequence of right hemisphere damage, usually of vascular origin, but also resulting from other causes such as neurodegenerative conditions. The study of neglect offers a key to understand the brain's functioning at the level of large-scale networks, and not only based on discrete anatomical structures. Patients are often unaware of their deficits (anosognosia), and often obstinately deny being hemiplegic. Diagnosis is important because neglect predicts poor functional outcome in stroke. Moreover, effective rehabilitation strategies are available, and there are promising possibilities for pharmacological treatments. Attention Disorders After Right Brain Damage is aimed at clinical neurologists, medics in physical medicine and rehabilitation, clinical psychologists and neuropsychologists. It will also be useful for graduate students and medical students who wish to understand the topic of attention systems and improve their knowledge of the neurocognitive mechanisms of attentional deficits. In addition, clinical researchers in neuropsychology and cognitive neuroscience will find in this book an up to date overview of current research dealing with the attention systems of the human brain.
  • Attention. 1st ed. 2009
    ScienceDirect
  • What is an atypical parkinsonian disorder? / Irene Litvan -- Historical issues and atypical parkinsonian disorders / Christopher G. Goetz -- Epidemiology of progressive supranuclear palsy and multiple system atrophy / Adam Zermansky and Yoav Ben-Shlomo -- Neuropathology of atypical parkinsonian disorders / Ian R.A. Mackenzie -- Animal models of tauopathies / Jada Lewis and Michael Hutton -- Neurodegenerative[alpha]-synucleinopathies / Michel Goedert and Maria Grazia Spillantini -- Computer modeling in basal ganglia disorders / José Luis Contreras-Vidal -- Atypical parkinsonian disorders: neuropathology and nosology / Charles Duyckaerts -- Genetics of atypical parkinsonism: implications for nosology / Thomas Gasser -- Medical history and physical examination in parkinsonian syndromes: how to examine a parkinsonian syndrome / Marie Vidailhet, Frédéric Bourdain, and Jean-Marc Trocello -- Role of neuropsychiatric assessment in diagnosis and research / Dag Aarsland, Uwe Ehrt, and Clive Ballard -- Added value of the neuropsychological evaluation for diagnosis and research of atypical parkinsonian disorders / Bruno Dubois and Bernard Pillon -- Role of praxis in diagnosis and assessment / Ramón Leiguarda -- Role of visuospatial cognition assessment in the diagnosis and research of atypical parkinsonian disorders / Paolo Nichelli and Anna Magherini -- Role of ocular motor assessment in diagnosis and research / R. John Leigh and David S. Zee -- Characterizing and assessing speech and language disturbances / Carol Frattali and Joseph R. Duffy -- Quality of life assessment in atypical parkinsonian disorders / Anette Schrag and Caroline E. Selai -- Progressive supranuclear palsy / Irene Litvan -- Corticobasal degeneration: the syndrome and the disease / Bradley F. Boeve -- Multiple system atrophy / Feliz Geser and Gregor K. Wenning -- Clinical diagnosis of dementia with Lewy bodies / David J. Burn, Urs P. Mosimann, and Ian G. McKeith -- Clinical diagnosis of familial atypical parkinsonian disorders / Yoshio Tsuboi, Virgilio H. Evidente, and Zbigniew K. Wszolek -- Clinical diagnosis of vascular parkinsonism and nondegenerative atypical parkinsonian disorders / Madhavi Thomas and Joseph Jankovic -- Role of electrophysiology in diagnosis and research in atypical parkinsonian disorders / Josep Valls-Solé -- Role of CT and MRI in diagnosis and research / Mario Savoiardo and Marina Grisoli -- Role of functional magnetic neuroimaging in diagnosis and research / Hartwig Roman Siebner and Günther Deuschl -- PET and SPECT imaging in atypical parkinsonian disorders / Alexander Gerhard and David J. Brooks -- Current and future therapeutic approaches / Elmyra V. Encarnacion and Thomas N. Chase -- Rehabilitation of patients with atypical parkinsonian disorders / Daniel K. White ... [et al.] -- Overview and future research / Andrew Lees.
  • Auditory cortex 2011
    Springer
  • ENGRAILED2 and cerebellar development in the pathogenesis of autism spectrum disorders / Ian T. Rossman and Emanuel DiCicco-Bloom -- Teratogenic alleles in autism and other neurodevelopmental disorders / William G. Johnson ... [et al.] -- Cholesterol deficit in autism : insights from Smith-Lemli-Opitz Syndrome / Alka Aneja and Elaine Tierney -- Autism in genetic intellectual disability : insights into idiopathic autism / Walter E. Kaufmann ... [et al.] -- Serotonin dysfunction in autism / Mary E. Blue ... [et al.] -- Excitotoxicity in autism : the role of glutamate in pathogenesis and treatment / Martin Evers and Eric Hollander -- Prenatal [beta]₂-adrenergic receptor signaling and autism : dysmaturation and retained fetal function / Susan L. Connors -- A role for fetal testosterone in human sex differences : implications for understanding autism / Bonnie Auyeung and Simon Baron-Cohen -- Interaction between genetic vulnerability and neurosteroids in purkinje cells as a possible neurobiological mechanism in autism spectrum disorders / Flavio Keller, Roger Panteri, and Filippo Biamonte -- Insulin-like growth factors : neurobiological regulators of brain growth in autism? / Raili Riikonen -- Oxidative stress and the metabolic pathology of autism / S. Jill James -- The immune system in autism : is there a connection? / Luke Heuer, Paul Ashwood, and Judy Van de Water -- Maternal immune activation, cytokines, and autism / Paul H. Patterson ... [et al.] -- Maternal antibodies and the placental-fetal IgG transfer theory / Christina M. Morris ... [et al.] -- Can neuroinflammation influence the development of autism spectrum disorders? / Carlos A. Pardo-Villamizar -- The significance of minicolumnar size variability in autism : a perspective from comparative anatomy / Manuel F. Casanova -- Imaging evidence for pathological brain development in autism spectrum disorders / Stephen R. Dager ... [et al.] -- Information processing, neural connectivity, and neuronal organization / Nancy J. Minshew, Diane L. Williams, and Kathryn McFadden -- Evidence for environmental susceptibility in autism : what we need to know about gene x environment interactions / Isaac N. Pessah and Pamela J. Lein -- An expanding spectrum of autism models : from fixed developmental defects to reversible functional impairments / Martha R. Herbert and Matthew P. Anderson.
  • Type, topography, and sequelae of neuropathological changes shaping clinical phenotype of autism / Jerzy Wegiel ... [et al.] -- Evidence for oxidative damage in the autistic brain / Teresa A. Evans ... [et al] -- Oxidative stress and neurotrophin signaling in autism / Elizabeth M. Sajdel-Sulkowska -- Genetics of autism / W. Ted Brown -- The phenotypic expression of autism, maternal depression, and the monoamine oxidase-a gene / Ira L. Cohen -- Paraoxonase 1 status, environmental exposures, and oxidative stress in autism spectrum disorders / Maria Dronca and Sergiu P. Pasca -- The redox/methylation hypothesis of autism : a molecular mechanism for heavy metal-induced neurotoxicity / Richard C. Deth -- Autism and oxidative stress : evidence from an animal model / Michelle A. Cheh ... [et al.] -- Neurotoxic brainstem impairment as proposed threshold event in autistic regression / Woody R. McGinnis ... [et al.] -- Abnormalities in membrane lipids, membrane-associated proteins, and signal transduction in autism / Ved Chauhan and Abha Chauhan -- Mitochondrial component of calcium signaling abnormality in autism / J. Jay Gargus -- Inflammation and neuroimmunity in the pathogenesis of autism : neural and immune network interactions / Carlos A. Pardo-Villamizar and Andrew W. Zimmerman -- Possible impact of innate immunity on autism / Harumi Jyonouchi -- Autism, gastrointestinal disturbance, and immune dysfunction : what is the link? / Paul Ashwood, Amanda Enstrom, and Judy van de Water -- Possible mechanism involving intestinal oxytocin, oxidative stress, and signaling pathways in a subset of autism with gut symptoms / Martha G. Welch and Benjamin Y. Klein -- Cytokine polymorphisms in autism : their role in immune alterations / Fabián Crespo ... [et al.] -- Autism, teratogenic alleles, HLA-DR4, and immune function / William G. Johnson ... [et al.] -- Autism : the centrality of active pathophysiology and the shift from static to chronic dynamic encephalopathy / Martha R. Herbert -- A re-evaluation of the state of autism treatment : the need for a biopsychosocial perspective / Eric London.
  • Time-frequency analysis : wavelet transforms -- Chaos theory -- Classifier designs -- Electroencephalograms and epilepsy -- Analysis of EEGs in an epileptic patient using wavelet transform -- Wavelet-chaos methodology for analysis of EEGs and EEG sub-bands -- Mixed-band wavelet-chaos neural network methodology -- Principal component analysis-enhanced cosine radial basis function neural network -- Alzheimer's disease and models of computation : imaging, classification, and neural models -- Alzheimer's disease : models of computation and analysis of EEGs -- A spatio-temporal wavelet-chaos methodology for EEG-based diagnosis of Alzheimer's disease -- Spiking neural networks : spiking neurons and learning algorithms -- Improved spiking neural networks with application to EEG classification and epilepsy and seizure detection -- A new supervised learning algorithm for multiple spiking neural networks -- Applications of multiple spiking neural networks : EEG classification and epilepsy and seizure detection.
  • Autonomic nervous system 2013
    ScienceDirect
    Autonomic Nervous System provides an introduction to the latest science and detailed chapters on advances in the clinical diagnosis and treatment of autonomic system disorders. The autonomic nervous system controls all involuntary actions within the human nervous system. Core body functions regulated by the autonomic system include breathing, heartbeat, blood pressure, body temperature, perspiration, and bowel, bladder and sexual function. Our understanding of the neurotransmitters associated with the autonomic nervous system has expanded over the past 15 years associated with current research efforts and are now impacting the diagnosis and treatment of autonomic nervous system disorders by clinical neurologists. This volume is a valuable companion for neuroscience and clinical neurology researchers and practitioners. A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurologyInternational list of contributors, including the leading workers in the fieldDescribes the advances that have occurred in clinical neurology and the neurosciences and their impact on the understanding of neurological disorders and on patient care.
  • Barrel cortex 2008
    ebrary
  • Basal ganglia IX 2009
    Springer
  • Basal ganglia VIII 2005
    Springer
    Oscillations in the basal ganglia -- Cholinergic mechanisms in the striatum -- Pharmacological and receptor studies of the basal ganglia -- Disorders of basal ganglia function I: studies in animal models -- Disorders of basal ganglia function II: clinical studies -- Physiological and anatomical studies of the functional organisation of the basal ganglia.
  • Peripheral processing -- Mosaic evolution of the mammalian auditory periphery -- A computer model of the auditory periphery and its application to the study of hearing -- A probabilistic account of absolute auditory thresholds and its possible physiological basis -- Cochlear compression: Recent insights from behavioural experiments -- Improved psychophysical methods to estimate peripheral gain and compression -- Contralateral efferent regulation of human cochlear tuning: Behavioural observations and computer model simulations -- Modeling effects of precursor duration on behavioral estimates of cochlear gain -- Is overshoot caused by an efferent reduction in cochlear gain? -- Accurate estimation of compression in simultaneous masking enables the simulation of hearing impairment for normal-hearing listeners -- Modelling the distortion produced by cochlear compression -- Temporal fine structure and pitch -- How independent are the pitch and the interaural-time-difference mechanisms that rely on temporal fine structure information? -- On the limit of neural phase-locking to fine-structure in humans -- Effects of sensorineural hearing loss on temporal coding of harmonic and inharmonic tone complexes in the auditory nerve -- A glimpsing account of the role of temporal fine structure information in speech recognition -- Assessing the possible role of frequency-shift detectors in the ability to hear out partials in complex tones -- Pitch perception: Dissociating frequency from fundamental-frequency discrimination -- Pitch perception for sequences of impulse responses whose scaling alternates at every cycle -- Putting the tritone paradox into context: insights from neural population decoding and human psychophysics -- Enhancement and perceptual compensation -- Spectral and level effects in auditory enhancement -- Enhancement of increments in spectral amplitude: further evidence for a mechanism based on central adaptation -- Differential sensitivity to appearing and disappearing objects in complex acoustic scenes -- Perceptual compensation when isolated test words are heard in room reverberation -- A new approach to sound source identification -- Binaural processing -- Maps of ITD in the Nucleus Laminaris of the Barn Owl -- The influence of the envelope waveform on binaural tuning of neurons in the inferior colliculus and its relation to binaural perception -- No evidence for ITD-specific adaptation in the frequency following response -- Interaural time difference thresholds as a function of frequency -- Interaural time processing when stimulus bandwidth differs at the two ears -- Neural correlates of the perception of sound source separation -- When and how envelope "rate-limitations" affect processing of interaural temporal disparities conveyed by high-frequency stimuli -- The sound source distance dependence of the acoustical cues to location and their encoding by neurons in the inferior colliculus: implications for the Duplex theory -- Cochlear contributions to the precedence effect -- Off-frequency BMLD: the role of monaural processing -- Measuring the apparent width of auditory sources in normal and impaired hearing -- Psychophysics of human echolocation -- Speech and temporal processing -- Formant-frequency variation and its effects on across-formant grouping in speech perception -- Do we need STRFs for cocktail parties? - On the relevance of physiologically motivated features for human speech perception derived from automatic speech recognition -- Modeling speech intelligibility in adverse conditions -- Better temporal neural coding with cochlear implants in awake animals -- Effects of auditory nerve refractoriness and adaptation on auditory perception -- Robust cortical encoding of slow temporal modulations of speech -- Wideband monaural envelope correlation perception -- Detection thresholds for amplitude modulations of tones in budgerigar (Melopsittacus undulatus) -- Phase discrimination ability in Mongolian gerbils provides evidence for possible processing mechanism of mistuning detection -- Auditory cortex and beyond -- Stimulus-specific adaptation beyond pure tones -- Mapping tonotopy in human auditory cortex -- Cortical activity associated with the perception of temporal asymmetry in ramped and damped noises -- Cortical representation of the combination of monaural and binaural unmasking -- Processing of short auditory stimuli: The Rapid Audio Sequential Presentation paradigm (RASP) -- Integration of auditory and tactile inputs in musical meter perception -- A dynamic system for the analysis of the acoustic features and valence of aversive sounds in the human brain -- Auditory scene analysis -- Can comodulation masking release occur when frequency changes would promote perceptual segregation of the on-frequency and flanking bands? -- Illusory auditory continuity despite neural evidence to the contrary -- High-acuity spatial stream segregation -- How early aging and environment interact in everyday listening: From brainstem to behaviour through modeling -- Energetic and informational masking in a simulated restaurant environment -- A computational model for the dynamic aspects of primitive auditory scene analysis -- A naturalistic approach to the cocktail party -- Temporal coherence and the streaming of complex sounds.
  • A comprehensive, state-of-the-art contribution to a field that is rapidly developing, The Behavioral Consequences of Stroke provides a broad overview of the cognitive and neurobehavioral effects of stroke. As attention to paralysis and the more obvious physical disabilities stroke patients incur expands, greater attention is being paid today to the cognitive and neurobehavioral complications that impact stroke morbidity and even functional neurological recovery in patients. Written by an international panel of experts and edited by a neurosurgeon and by a cognitive neuroscientist, this unique title addresses the full range of issues relevant to the field, including epidemiology, general treatment, sensorimotor control after stroke, post-stroke aphasia, memory loss after stroke, post-stroke depression, the role of imaging after a stroke, and an update on some stroke clinical trials, to name just some of the areas covered. Illuminative and an influential addition to the literature, The Behavioral Consequences of Stroke will serve as an invaluable resource for neurologists, neurosurgeons, physiatrists and other physicians, as well as physical, speech and occupational therapists, nurses, psychologists, and other professionals.
  • Epidemiology of Cognitive Aging and Alzheimer's Disease: Contributions of the Cache County Utah Study of Memory, Health and Aging / Kathleen M. Hayden and Kathleen A. Welsh-Bohmer -- Successful Cognitive Aging / Colin A. Depp, Alexandria Harmell and Ipsit V. Vahia -- Behavioral Neuroscience of Emotion in Aging / Alfred W. Kaszniak and Marisa Menchola -- Studying the Impact of Aging on Memory Systems: Contribution of Two Behavioral Models in the Mouse / Aline Marighetto, Laurent Brayda-Bruno and Nicole Etchamendy -- Functional Neuroimaging Studies in Normal Aging / Leslie M. Guidotti Breting, Elizabeth R. Tuminello and S. Duke Han -- Functional Magnetic Resonance Imaging in Aging and Dementia: Detection of Age-Related Cognitive Changes and Prediction of Cognitive Decline / John L. Woodard and Michael A. Sugarman -- Neuroanatomical Changes Associated with Cognitive Aging / Janice M. Juraska and Nioka C. Lowry. The Impact of Age-Related Ovarian Hormone Loss on Cognitive and Neural Function / Marissa I. Boulware, Brianne A. Kent and Karyn M. Frick -- Neuropsychological Features of Mild Cognitive Impairment and Preclinical Alzheimer's Disease / David P. Salmon -- Cerebrovascular Disease and Cognition in Older Adults / Gregory A. Seidel, Tania Giovannetti and David J. Libon -- Psychiatric Disorders in Ageing / C. Wijeratne, S. Reutens, B. Draper and P. Sachdev -- The Impact of Physical and Mental Activity on Cognitive Aging / Amy J. Jak -- Potential Benefits and Limitations of Enriched Environments and Cognitive Activity on Age-Related Behavioural Decline / Rosa Redolat and Patricia Mesa-Gresa -- Reproductive Experience may Positively Adjust the Trajectory of Senescence / Craig Howard Kinsley, R. Adam Franssen and Elizabeth Amory Meyer -- Treatment Trials in Aging and Mild Cognitive Impairment / Jody Corey-Bloom.
  • Part I. Mechanistic Aspects Underlying Alcoholism -- Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit Disorder / George F. Koob -- Synaptic Effects Induced by Alcohol / David M. Lovinger and Marisa Roberto -- Signaling Pathways Mediating Alcohol Effects / Dorit Ron and Robert O. Messing -- Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Access Points / Bo Söderpalm and Mia Ericson -- What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol / Gerald A. Deehan Jr., Mark S. Brodie and Zachary A. Rodd -- Part II. Genetics -- Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models / John C. Crabbe, Kenneth S. Kendler and Robert J. Hitzemann -- Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental Factors / Christina S. Barr -- Genetically Selected Alcohol Preferring Rats to Model Human -- Alcoholism / Roberto Ciccocioppo -- Advanced Transgenic Approaches to Understand Alcohol-Related Phenotypes in Animals / Ainhoa Bilbao -- Part III. Clinical Phenotypes and Preclinical Models Thereof Modeling Alcohol Self-Administration in the Human Laboratory / Ulrich S. Zimmermann, Sean O'Connor and Vijay A. Ramchandani -- Animal Models of Excessive Alcohol Consumption in Rodents / Howard C. Becker -- Modeling Relapse Situations in the Human Laboratory / Rajita Sinha -- Modeling Relapse in Animals / Rémi Martin-Fardon and Friedbert Weiss -- Invertebrate Models of Alcoholism / Henrike Scholz and Julie A. Mustard -- Part IV. Novel Insights from Brain Imaging The Dopamine System in Mediating Alcohol Effects in Humans / K. Charlet, A. Beck and A. Heinz -- Stimulant and Sedative Effects of Alcohol / Reuben A. Hendler, Vijay A. Ramchandani, Jodi Gilman and Daniel W. Hommer -- Chronic Alcohol Consumption, Abstinence and Relapse: Brain Proton Magnetic Resonance Spectroscopy Studies in Animals and Humans / Dieter J. Meyerhoff, Timothy C. Durazzo and Gabriele Ende -- Part V. Translational Aspects and Medication Development -- Translational Approaches to Medication Development / Selena Bartlett and Markus Heilig -- New Pharmacological Treatment Strategies for Relapse Prevention / Rainer Spanagel and Valentina Vengeliene -- The Challenge of Studying Parallel Behaviors in Humans and Animal Models / David N. Stephens, Hans S. Crombag and Theodora Duka -- A Translational Approach to Novel Medication Development for Protracted Abstinence / Barbara J. Mason and Amanda E. Higley -- New Approaches to Addiction Treatment Based on Learning and Memory / Falk Kiefer and Christina Dinter -- Adolescent Substance Misuse: Neurobiology and Evidence-Based Interventions / Nicola C. Newton, Maeve O'Leary-Barrett and Patricia J. Conrod -- Deep Brain Stimulation as a Therapy for Alcohol Addiction / Thomas F. Münte, Hans-Jochen Heinze and Veerle Visser-Vandewalle.
  • Course and Outcome of Bipolar Disorder /Philip B. Mitchell, Dusan Hadzi-Pavlovic, and Colleen K. Loo -- Genetics of Bipolar Disorder / Jens R. Wendland and Francis J. McMahon -- Understanding Bipolar Disorder: The Epigenetic Perspective / Tarang Khare, Mrinal Pal, and Arturas Petronis -- Clinical Endophenotypes for Bipolar Disorder / David C. Glahn and Katherine E. Burdick -- Strategies for the Development of Animal Models for Bipolar Disorder: New Opportunities and New Challenges / Haim Einat -- Partial Rodent Genetic Models for Bipolar Disorder / Guang Chen, Ioline D. Henter, and Husseini K. Manji -- The Role of the Aminergic Systems in the Pathophysiology of Bipolar Disorder / Espen Walderhaug, Monica Varga, Michelle San Pedro, Jian Hu, and Alexander Neumeister -- The Neurobiology of Bipolar Disorder: From Circuits to Cells to Molecular Regulation / Francine M. Benes -- Signal Transduction Pathways in the Pathophysiology of Bipolar Disorder / Jeremy W. Gawryluk and L. Trevor Young -- Synaptic Plasticity in the Pathophysiology and Treatment of Bipolar Disorder / Jing Du, Rodrigo Machado-Vieira, and Rushaniya Khairova -- Mitochondrial Dysfunction and Bipolar Disorder / Tadafumi Kato -- Neuroimaging and Neuropathological Findings in Bipolar Disorder / Jonathan Savitz and Wayne C. Drevets Functional Neuroimaging Research in Bipolar Disorder / Benjamin N. Blond and Hilary P. Blumberg -- Sleep and Circadian Rhythm Abnormalities in the Pathophysiology of Bipolar Disorder / Jessica Levenson and Ellen Frank --Pharmacological Treatments for Bipolar Disorder: Present Recommendations and Future Prospects / Charles L. Bowden -- Nonpharmacotherapeutic Somatic Treatments for Bipolar Disorder (ECT, DBS, rTMS) / Colleen Loo, Benjamin Greenberg, and Philip Mitchell -- Potential Novel Therapeutics for Bipolar Disorders / Rodrigo Machado-Vieira, Husseini K. Manji, and Carlos A. Zarate Jr. -- Bipolar Disorder: A Neurobiological Synthesis / Husseini K. Manji, Ioline D. Henter, and Carlos A. Zarate -- Index.
  • This volume brings together a series of authoritative chapters written by leading experts in preclinical and clinical aspects of pain neurobiology. It is essential reading for scientists, clinicians and students in need of a comprehensive review of behavioral readouts for the preclinical assessment of chronic pain and analgesic drug efficacy, or those with a general interest in behavioral neuroscience. At the core of this volume are emerging details of the physiology, pharmacology, and psychology of previously neglected types of chronic pain. These types include chronic post-operative pain in humans as well as animal behavioral assays that model the chronic pain of multiple sclerosis, post-herpetic neuralgia, painful diabetic neuropathy, visceral pain, latent central sensitization, and chronic muscle pain. Also emphasized are the complex bidirectional comorbidities between chronic pain and drug dependence, cognitive deficit, stress, anxiety, depression, social interaction, and prior injury history. The novel and exciting ideas introduced within this book, such as endogenous opioid dependence after tissue injury, generate real hope that effective treatment strategies for chronic pain will emerge in the near future.
  • Cognition and emotions in eating disorders -- Personality and temperment Lisa Rachelle Riso Lilenfeld -- Cognitions and emotions in eating disorders / Nicolette Siep, Anita Jansen, Remco Havermans, and Anne Roefs -- Neural circuits, neurotransmitters, and behavior -- Neurocircuitry of eating disorders / Walter H. Kaye, Angela Wagner, Julie L. Fudge, and Martin Paulus -- Serotonin: imaging findings in eating disorders / Ursula F. Bailer and Walter H. Kaye -- Dopamine-based reward circuitry responsivity, genetics and overeating / Eric Stice, Sonja Yokum, David Zald, and Alain Dagher -- Reward and neurocomputational processes / Guido K. W. Frank -- Cognitive-behavioral flexibility in anorexia nervosa / Hans-Christoph Friederich and Wolfgang Herzog -- Neural circuits, neurotransmitters and behavior / Howard Steiger, Kenneth R. Bruce, and Patricia Groleau -- Genetics, gender and heritability -- The heritability of eating disorders: methods and current findings / Laura M. Thornton, Suzanne E. Mazzeo, and Cynthia M. Bulik -- The genetics of eating disorders / Sietske G. Helder and David A Collier -- The influence of gender and puberty on the heritablility of disordered eating symptons / Kristen M. Culbert, Sarah E. Racine, and Kelly L. Klump -- Neuroendocrinology and animal research -- New frontiers in endocrinology of eating disorders / Palmiero Monteleone -- Animal models of eating disorder traits / Martien J. H. Kas and Roger A. H. Dan -- Neurobiology driving hyperactivity in activity-based anorexia / R. A. H. Adan, J. J. G. Hillebrand, U. N. Dammer, S. Cardona Cano, M. J. H. Kas, and L. A. W. Verhagen -- Translational approach to treatment -- Translating experimental neuroscience into treatment of eating disorders: two examples / Ulrike Schmidt, Anna Oldershaw, and Annemarie van Elburg -- Cognitive remediation therapy for eating disorders; development, refinement and future directions / Kate Tchanturia and James Lock -- Incorporating dispositional traits into the treatment of anorexia nervosa / Nancy L. Zucker, David Herzog, Ashley Moskovich, Rhonda Merwin, and Tammy Lin.
  • Front Matter -- Diagnosis and Revision of the Classification Systems / Assen Jablensky -- Pathophysiology of Schizophrenia / Peter Falkai, Andrea Schmitt, Tyrone D Cannon -- Neurocognition, Social Cognition and Functional Outcome in Schizophrenia / William P Horan, Philippe-Olivier Harvey, Robert S Kern, Michael F Green -- The Genetics of Schizophrenia / James T R Walters, Michael O'Donovan, Michael J Owen, Wolfgang Gaebel -- Early Recognition and Prevention of Schizophrenia / Patrick D McGorry, Sherilyn Goldstone -- Pharmacological Treatment / Jonathan E Sherin, Stephen R Marder -- Cognitive-Behavioural Interventions / Suzanne Jolley, Philippa Garety -- Management, Rehabilitation, Stigma / Wulf R̲ssler -- Index.
  • Stress is such an over-used word that it is at time difficult to define its core features. When is an environment stressful? What does a stressful environment do to the brain and to the body? What are the biological mechanisms by which a stressor affects us? How does stress contributes to the onset and the progression of mental disorders? How do the effects of stress change over the life-time of an individual? These are just some of the overarching questions addressed by this book, thanks to the contribution of some of the world leading experts on the neurobiology of stress at the pre-clinical and clinical levels. Topics include current advances on the neurobiology of stress on various neurobiological systems such as immune, hypothalamic-pituitary-adrenal (HPA) axis, neurogenesis and neuroplasticity, neurotransmitter (glutamate, noradrenaline, dopamine, serotonin and endocannabinoid), neuropeptides, cognition and emotional processing as well as in utero and early postnatal effects. The clinical chapters deal with the relationship of stress and mental disorders such as depression, posttraumatic stress disorder (PTSD), anxiety disorders, schizophrenia, bipolar disorder, substance abuse and addiction, dementia and age-related cognitive decline as well as resilience to stress. Thus, this book brings together some of the most updated and authoritative views on the effects of stress of brain and behavior.
  • ADHD in children and adults: diagnosis and prognosis / Renata Kieling and Luis A. Rohde -- ADHD: volumetry, motor, and oculomotor functions / E. Mark Mahone -- Neurodevelopmental abnormalities in ADHD / Chandan J. Vaidya -- Intraindividual variability in ADHD and its implications for research of causal links / Jonna Kuntsi and Christoph Klein -- Hypothalamic-pituitary-adrenocortical axis function in attention-deficit hyperactivity disorder / Graeme Fairchild -- Brain processes in discounting : consequences of adolescent methylphenidate exposure / Walter Adriani, Francesca Zoratto, and Giovanni Laviola -- Attention deficit hyperactivity disorder and substance use disorders / Oscar G. Bukstein -- Linking ADHD, impulsivity, and drug abuse : a neuropsychological perspective / Gonzalo P. Urcelay and Jeffrey W. Dalley -- Obesity and ADHD : clinical and neurobiological implications / Samuele Cortese and Brenda Vincenzi -- Face processing in attention deficit/hyperactivity disorder / Daniel P. Dickstein and F. Xavier Castellanos -- Quantitative and molecular genetics of ADHD / Philip Asherson and Hugh Gurling -- Rodent models of ADHD / Xueliang Fan, Kristy J. Bruno, and Ellen J. Hess -- Rat models of ADHD / Terje Sagvolden and Espen Borgå Johansen -- Epigenetics: genetics versus life experiences / Josephine Elia ... [et al.] -- Sexual differentiation of the brain and ADHD: what is a sex difference in prevalence telling us? / Jaylyn Waddell and Margaret M. McCarthy -- ADHD : current and future therapeutics / David J. Heal, Sharon L. Smith, and Robert L. Findling -- Four causes of ADHD: a framework / Peter R. Killeen, Rosemary Tannock, and Terje Sagvolden.
  • Best practices in neurological care / Bruce Ovbiagele -- Epilepsy / Omotola A. Hope & Jeremy Lankford -- Parkinson's disease / Jori Fleisher & Nabila Dahodwala -- Neuromuscular diseases / Hajime Tokuno, Pooia Fattahi & Huned S. Patwa -- Dementia / Liana G. Apostolova -- Headache / Charles C. Flippen II -- Brain tumor management / Seema Nagpal, Scott G. Soltys, Gordon Li, Griffith Harsh & Lawrence Recht -- Neuroinfectious diseases / David Croteau -- Stroke / Shelly Ozark, Diana Goodman & Christine Holmstedt -- Multiple sclerosis / Lily Jung Henson -- Evidence-based therapies in neurologic rehabilitation / Bruce H. Dobkin & Andrew Dorsch -- Neurocritical care / Paul Vespa & Vikas Grover -- Palliative care in neurology / Eli L. Diamond & Alan C. Carver -- Index.
  • "Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are serious, debilitating conditions that affect millions of people in the United States and around the world. ME/CFS can cause significant impairment and disability. Despite substantial efforts by researchers to better understand ME/CFS, there is no known cause or effective treatment. Diagnosing the disease remains a challenge, and patients often struggle with their illness for years before an identification is made. Some health care providers have been skeptical about the serious physiological - rather than psychological - nature of the illness. Once diagnosed, patients often complain of receiving hostility from their health care provider as well as being subjected to treatment strategies that exacerbate their symptoms. eyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome proposes new diagnostic clinical criteria for ME/CFS and a new term for the illness - systemic exertion intolerance disease (SEID). According to this report, the term myalgic encephalomyelitis does not accurately describe this illness, and the term chronic fatigue syndrome can result in trivialization and stigmatization for patients afflicted with this illness. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome stresses that SEID is a medical - not a psychiatric or psychological - illness. This report lists the major symptoms of SEID and recommends a diagnostic process.One of the report's most important conclusions is that a thorough history, physical examination, and targeted work-up are necessary and often sufficient for diagnosis. The new criteria will allow a large percentage of undiagnosed patients to receive an accurate diagnosis and appropriate care. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome will be a valuable resource to promote the prompt diagnosis of patients with this complex, multisystem, and often devastating disorder; enhance public understanding; and provide a firm foundation for future improvements in diagnosis and treatment"--Publisher's description.
  • Angiogenesis plays a key role in human physiology and pathophysiology. While necessary for tissue growth and development, uncontrolled angiogenesis plays a role in the progression of certain tumors as well as atherosclerosis. Lack of angiogenesis may be the basis of myocardial ischemia and stroke. Knowledge on the mechanisms of angiogenesis is growing very rapidly, and may lead to important drugs for therapy of a variety of clinical disorders. Experts from around the world have contributed a vast array of data on different aspects of angiogenesis in this volume edited by Professors Mehta and Dhalla. This information will be of immense help to basic scientists, clinicians and those involved in drug development.
  • Attention-deficit/hyperactivity disorder / Coghill, D., Rohde, L.A., Banaschewski, T. -- Autism / Moura, P.J., Lombroso, P.J., Mercadante, M.T. -- Brain model for pediatric bipolar disorder / Pavuluri, M.N., Bogarapu, S.P. -- Neurobiology of depression in childhood and adolescence / Bark, C., Resch, F. -- The neurobiological basis of anxiety in children and adolescents / Grados, M.A. -- Obsessive-compulsive disorder in childhood / Rosário, M.C. ... [et al.] -- Neurobiological background of tic disorders / Roessner, V., Rothenberger, A. -- Schizophrenia in children and adolescents / Remschmidt, H. -- Eating disorders / Fleitlich-Bilyk, B., Lock, J. -- Conduct disorder / Popma, A., Vermeiren, R. -- Substance use disorders in adolescence / Szobot, C.M., Bukstein, O. -- Molecular genetics in child psychiatry / Stringaris, A.K., Asherson, P. -- Recent developments in neuropsychological models of childhood psychiatric disorders / Willcutt, E.G. ... [et al.] -- Electrophysiology in child psychiatric disorders / Banaschewski, T., Brandeis, D. -- Neuroimaging in child psychiatry / Durston, S.
  • Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible.
  • Morphology and properties of brain endothelial cells -- Morphology and properties of pericytes -- Morphology and properties of astrocytes -- The blood-cerebrospinal fluid barrier: Structure and functional significance -- The blood-retinal barrier: Structure and functional significance -- The blood-nerve barrier: Structure and functional significance -- Detection of multiple proteins in intracerebral vessels by confocal microscopy -- Multiparametric magnetic resonance imaging and repeated measurements of blood-brain barrier permeability to contrast agents -- Detection of brain pathology by magnetic resonance imaging of iron oxide micro-particles -- Measuring the integrity of the human blood-brain barrier using magnetic resonance imaging -- Assessing blood-cerebrospinal fluid barrier permeability in the rat embryo -- Detection of blood-nerve barrier permeability by magnetic resonance imaging -- Isolation of human brain endothelial cells and characterization of lipid raft-associated proteins by mass spectroscopy -- Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics -- Molecular and functional characterization of P-glycoprotein in vitro -- Methods to study glycoproteins at the blood-brain barrier using mass spectrometry -- Novel models for studying the blood-brain and blood-eye barriers in drosophila -- Zebrafish model of the blood-brain barrier: Morphological and permeability studies -- Methods to assess pericyte-endothelial cell interactions in a coculture model -- Isolation and properties of an in vitro human outer blood-retinal barrier model -- Isolation and properties of endothelial cells forming the blood-nerve barrier -- Treatment of focal brain ischemia with viral vector-mediated gene transfer -- Blood-brain barrier disruption in the treatment of brain tumors -- Integrated platform for brain imaging and drug delivery across the blood-brain barrier -- Targeting the choroid plexus-CSF-brain nexus using peptides identified by phage display.
  • Principles of functional MRI -- fMRI scanning methodologies -- Experimental design and data analysis for fMRI -- Challenges in fMRI and its limitations -- Clinical challenges of fMRI -- Brain mapping for neurosurgery and cognitive neuroscience -- fMRI of memory in aging and dementia -- fMRI of language systems: methods and applications -- fMRI Wada test: prospects for presurgical mapping of language and memory -- Cognitive neuroscience applications -- Neuroanatomical atlas.
  • v. 1. Principles of diagnosis and management -- v. 2. Neurological disorders.
  • Brain Aging: A Critical Reappraisal / Mahendra K. Thakur, Arpita Konar, Akash Gautam -- Base Excision DNA Repair: The House Keeping Guardian for Genomic Stability in the Brain / Umakanta Swain, Kalluri Subba Rao -- Role of Brain-Derived Neurotrophic Factor as a Modulator of Synaptic Plasticity / Yasuyuki Ishikawa, Masami Kojima -- Mitochondrial Dysfunction in Sporadic Alzheimer's Disease: Mechanisms, Consequences and Interventions / Sasanka Chakrabarti, Maitrayee Sinha -- Brain Aging: Influence of Early-Life Events on Late-Life Brain Disorders / Debomoy K. Lahiri -- The Importance of the Environment in Brain Aging: Be Happy, Live Longer! / Mónica De la Fuente, Lorena Arranz -- Consequences of Altered Mortalin Expression in Control of Cell Proliferation and Brain Function / Renu Wadhwa, Sunil C. Kaul -- Age- Induced Alterations in Biological Clock: Therapeutic Effects of Melatonin / Anita Jagota -- Neurolipofuscin in Aging and Aluminum-Induced Aging: Possible Therapeutic Interventions / Mahdi Hasan, Sandeep Tripathi, Abbas A. Mahdi -- Dietary Restriction as a Potential Intervention to Retard Age-associated Impairment of Brain Functions / Gurcharan Kaur, Sukhwinder S. Lakhman -- Understanding Mechanism of Action of Herbal Drugs in Age Related Degenerative Brain Disorders / Maheep Bhatnagar, Ayushi Jain, Neha Jaiswal -- Neurodegeneration in Hypoxia: Implications in Aging / Kalpana Barhwal Hota, Sunil Kumar Hota -- Stress and Memory: from Mechanisms to Long-Lasting Consequences / Harmen J. Krugers, Marian Joels -- Estrogen-Mediated Neuroprotection: Hope to Combat Neuronal Degeneration and Synaptic Plasticity Post-menopause / Raj D. Mehra, Mukesh K. Varshney, Pavan Kumar -- Potential Therapeutic Targets for Improving Memory Impairments and Dementia: Clues Obtained from Memory-Enhanced Mice / Shogo Endo -- Potential Beneficial Effects of a Diet with Walnuts in Aging and Alzheimer's Disease / Abha Chauhan, Ved Chauhan -- Smart Dietary Interventions and Prevention of Cognitive Decline with Aging / S. Asha Devi -- Herbal Cognitive Enhancers: New Developments and Challenges for Therapeutic Applications / Andrea Zangara, Keith A. Wesnes.
  • Changes in cognitive function in human aging / Elizabeth Glisky -- Successful versus unsuccessful cognitive aging in Rhesus monkeys / Mark B. Moss ... [et al.] -- Neuropsychology of cognitive aging in rodents / Joshua S. Rodefer -- Design-based stereology in brain aging research / Cristoph Schmitz -- The effects of normal aging on nerve fibers and neuroglia in the central nervous system / Alan Peters -- Neurogenesis in the adult and aging brain / David R. Riddle -- Expression profile analysis of brain aging / Steve Ginsberg -- Subtle alterations in glutamatergic synapses underlie the aging-related declines in hippocampal function / Lei Shi, Michelle Adams, and Judy Brunso-Bechtold -- Assessment of second messenger function in the hippocampus of aged rats with cognitive impairment / Michelle M. Nicolle, H. Zhang, Jennifer L. Bizon -- Neurophysiology of old neurons and synapses / Ashok Kumar and Thomas C. Foster -- Imaging cognition in the aging human brain / Trey Hedden -- Regulation of cerebrovascular aging / William Sonntag, Jeremy Ingraham, and Delrae Eckman -- Stress and glucocorticoid contributions to normal and pathological aging / Ki A. Goosens and Robert Sapolsky -- Altered calcium homeostasis in old neurons / Emil Toescu -- Oxidative stress in aging / Jennifer Vila and Paula C. Bickford. Changes in cognitive function in human aging / Elizabeth L. Glisky -- Successful vs. unsuccessful aging in the Rhesus monkey / Mark B. Moss ... [et al.] -- Neuropsychology of cognitive aging in rodents / Joshua S. Rodefer and Mark G. Baxter -- Design-based stereology in brain aging research / Cristoph Schmitz and Patrick R. Hof -- The effects of normal aging on nerve fibers and neuroglia in the central nervous system / Alan Peters -- Neurogenesis in the adult and aging brain / David R. Riddle and Robin J. Lichtenwalner -- Expression profile analysis of brain aging / Stephen D. Ginsberg -- Subtle alterations in glutamatergic synapses underlie the aging-related decline in hippocampal function / Lei Shi, Michelle Adams, and Judy K. Brunso-Bechtold -- Assessment of second messenger function in the hippocampus of aged rats with cognitive impairment / Michelle M. Nicolle, Hai-Yan Zhang, and Jennifer L. Bizon -- Neurophysiology of old neurons and synapses / Ashok Kumar and Thomas C. Foster -- Imaging cognition in the aging human brain / Trey Hedden -- Regulation of cerebrovascular aging / William E. Sonntag ... [et al.] -- Stress and glucocorticoid contributions to normal and pathological aging / Ki A. Goosens and Robert M. Sapolsky -- Altered calcium homeostasis in old neurons / Emil C. Toescu -- Oxidative stress and the aging brain: from theory to prevention / Carmelina Gemma ... [et al.].
  • Brain cancer 2010
    Springer
  • The human brain has long been a mystery, but twenty-first century science is beginning to reveal some of its inner workings. With microscopes and brain scans, with psychological experiments and breakthroughs in genetics, neuroscientists are developing new theories about every aspect of our minds--from the nature of consciousness to the causes of disorders like autism and schizophrenia. In Brain Cuttings, award-winning science writer Carl Zimmer takes readers on fascinating explorations of the frontiers of research, shedding light on our innermost existence--the speed of thought, our perception o.
  • The development of the Drosophila larval brain -- Anteroposterior regionalization of the brain: genetic and comparative aspects -- Dorsoventral patterning of the brain: a comparative approach -- Dissection of the embryonic brain using photoactivated gene expression -- Design of the larval chemosensory system -- Development of the Drosophila olfactory system -- The olfactory sensory map in drosophila -- Optic lobe development -- Clonal unit architecture of the adult fly brain.
  • This book describes the latest research on neurodegenerative disease and metal-binding proteins. It lays strong emphasis on biochemistry and cell biology. The diseases covered in the book include Parkinson's disease, Alzheimer's disease, prion disease, and ALS. The chapters separately examine such issues as mechanisms of metal binding, metal-induced structural changes in proteins, alterations in cellular metal metabolism in disease, and attempts at a therapeutic approach based on protein metal binding.
  • Brain edema XV 2013
    Springer
    Historical review -- Ischemia & hemorrhage -- Trauma (experimental) -- Trauma (clinical) -- Cerebral Hemorrhage -- Tumor -- Hydrocephalus & intracranial pressure (ICP) -- Neuromonitoring & neuroimaging -- Treatments -- Blood brain barrier, miscellaneous.
  • Brain edema. XIII 2006
    Springer
  • Brain edema. XIV 2010
    Springer
  • Brain imaging 2008
    Thieme
    Trauma -- Cerebral contusion -- Diffuse axonal injury -- Subdural hematoma (SDH) -- Epidural hematoma -- Traumatic subarachnoid hemorrhage -- Cerebral edema -- Herniation syndromes -- Skull fracture -- Inflammation -- Multiple sclerosis (MS) -- Postinfectious encephalomyelitis (ADEM) -- Herpes simplex encephalitis -- Cerebral abscess - Meningitis -- Cerebral vasculitis -- Toxoplasmosis -- Progressive multifocal leukoencephalopathy (PML) -- Tuberculosis of the CNS -- CNS cysticercosis -- Aneurysms -- Subarachnoid hemorrhage (SAH) -- Saccular aneurysm -- Fusiform aneurysm --Vascular malformations -- Cavernous hemangioma -- Venous dysplasia -- Capillary telangiectasia -- Pial arteriovenous malformation (AVM) -- Cranial dural arteriovenous fistula -- Variants of vascular anatomy -- Vascular compression syndromes -- Stroke -- Ischemic brain infarction -- Cerebral microangiopathy -- Primary intracerebral hemorrhage --- Amyloid angiopathy -- Vascular dissection -- Impaired venous drainage -- Diffuse hypoxic brain damage -- Tumors -- Meningioma - Higher grade gliomas -- Brain metastasis -- Low-grade astrocytoma -- Primary CNS lymphoma -- Sellar masses -- Nerve sheath tumors -- Oligodendroglioma -- Pilocytic astrocytoma -- Medulloblastoma -- Pineal tumors -- Epidermoid -- Embryonal tumors -- Ependymoma -- Glioneuronal tumors -- Hemangioblastoma -- Gilomatosis cerebri --Choroid plexus papilloma -- Cysts -- Arachnoid cyst -- Virchow-Robin spaces -- Pineal cyst -- Colloid cyst -- Rathke cleft cyst -- Choroid plexus cyst -- Meninges -- Meningeal carcinomatosis -- Reactive memingeal enhancement -- CNS sarcoidosis -- Ventricles and cisterns -- Obstructive hydrocephalus -- Idiopathic normal-pressure hyudrocephalus -- Pseudotumor cerebri -- Leukoencephalopathies -- Wallerian degeneration -- Alzheimer disease -- Central pontine myelinolysis -- Toxic leukoencephalopathies -- Reversible posterior leukoencephalopathy -- Multiple system atrophy -- Wilson Disease -- Hepatic encephalopathy -- Amyotrophic lateral sclerosis (ALS) -- Wernicke encephhalopathy -- Superficial siderosis of the brain -- Congenital malformations -- Chiari malformations -- Defective migration -- Anomalies of the corpus callosum -- Dandy-Walker complex -- Periventricular leukomalacia (PVL) -- Neurofibromatosis type 1 (Von Recklinghausen Disease) -- Neurofibromatosis type II -- Tuberous sclerosis (Bourneville-Pringle Disease) -- Sturge-Weber Syndrome -- Von Hippel-Lindau Syndrome -- Holoprosencephaly -- Artifacts in MRI -- Postoperative changes.
  • Brain imaging in behavioral medicine and clinical neuroscience: an introduction -- Basic MR physics: considerations for behavioral medicine and neurophysiology -- Functional magnetic resonance imaging -- Diffusion-tensor imaging and behavioral medicine -- Perfusion MRI -- Proton magnetic resonance spectroscopy: a practical guide for the clinical neuroscientist -- Functional near-infrared spectroscopy -- Methodological considerations for using bold fMRI in the clinical neurosciences -- Application of functional neuroimaging to examination of nicotine dependence -- Relationship between mood, stress, and tobacco smoking -- Imaging substance use and misuse: psychostimulants -- Eating disorders -- Structural and functional neuroimaging in obesity -- Neuropsychology and neuroimaging in metabolic dysfunction -- Neuroimaging of cardiovascular disease -- Exercise and the brain -- Neuroimaging of pain: a psychosocial perspective -- Neuroimaging in acute ischemic stroke -- Neuroimaging of Alzheimer's disease, mild cognitive impairment, and other dementias -- Application of neuroimaging methods to define cognitive and brain abnormalities associated with HIV -- Neuroimaging and cognitive function in multiple sclerosis -- Neuroimaging of fatigue -- Brain imaging in behavioral medicine and clinical neuroscience: synthesis.
  • The Cytokine System -- The Discovery of the Brain Immunomodulators -- Brain Neuroendocrine Immune System: Neurosecretion of Interleukins and New Cytokines Produced by NSO and NPV of Hypothalamus -- Antibacterial and Antiviral Activity of PRP-1 (Galarmin) and Some Immunological Mechanisms of its Action -- Treatment and Prophylaxis of Anthrax by Galarmin: Receptor Tyrosine Kinases is a Target of Galarmin -- Prophylaxis and Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection with Proline-Rich Polypeptides Galarmin and Its Structural Analogues in an Experimental Murine Model -- Treatment of Clostridium Perfringens-induced Gas Gangrene by New Cytokines of Brain -- Hypothalamic, Proline-Rich Polypeptide (Galarmin) has Protective and Immunogenic Activity on Experimental Mycobacterium Tuberculosis Infection -- Brain-Bone Marrow Neurohumoral Axis: Galarmin Controls Differentiation, Proliferation and Mobilization of Bone Marrow Progenitor cells -- Antioxidant-Antiradical and Electron Donating Function of Galarmin and Gx-NH2 -- Discussion -- Summary.
  • pt. 1. What educators need to know about the brain -- 1. Introduction and conceptual foundations -- 2. General principles of microstructure and microfunction -- 3. General principles of macrostructure and macrofunction -- 4. General principles of brain development -- pt. 2. Linking brain research to literacy research -- 5. Building a reading brain neurologically -- 6. Building a writing brain neurologically -- 7. Building a computing brain neurologically -- pt. 3. Linking literacy research to brain research -- 8. Building a reading brain pedagogically -- 9. Building a writing brain pedagogically -- 10. Building a computing brain pedagogically -- pt. 4. Educational applications of brain-literacy links -- 11. Implications for educational policy -- 12. Implications for classroom practice.
  • Making the lifetime connection between brain and machine for restoring and enhancing function -- Out of the frying pan into the fire: the P300-based BCI faces real-world challenges -- Toward a whole-body neuroprosthetic -- Biocompatible multichannel electrodes for long-term neurophysiological studies and clinical therapy: novel concepts and design -- Deep brain stimulation: BCI at large, where are we going to? -- Deep brain stimulation: emerging indications -- Development of neuromodulation treatments in a large animal model: Do neurosurgeons dream of electric pigs? -- Few examples of the contribution of animal research in rodents for clinical application of deep brain stimulation -- Cochlear implants: matching the prosthesis to the brain and facilitating desired plastic changes in brain function -- Multimodal, longitudinal assessment of intracortical microstimulation -- Functional consequences of chronic, physiologically effective intracortical microstimulation -- Reducting surface area while maintaining implant penetrating profile lowers the brain foreign body response to chronically implanted planar silicon microelectrode arrays -- Can histology solve the riddle of the nonfunctioning electrode? Factors influencing the biocompatibility of brain machine interfaces -- Changes in CNS structures after spinal cord lesions: implications for BMI -- Modeling the potentiality of spinal-like circuitry for stabilization of a planar arm system -- Advances in the use of electrical stimulation for the recovery of motor function -- Intraspinal microstimulation for the recovery of function following spinal cord injury -- Interfacing neurons with carbon nanotubes: (re)engineering neuronal signaling -- Nanomodified surfaces and neurite outgrowth -- Direct local polymerization of poly(3,4-ethylenedioxythiophene) in rat cortex.
  • Brain metastases 2007
    Springer
  • With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. This volume fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types -- lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection.
  • Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors fills that gap, serving as the first two-part reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types - lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age- and gender-related trends are also discussed, as is the use of biomarkers for early detection.
  • Molecular and biochemical basis of brain injury following heart surgery: interventions for the future -- Cardiopulmonary bypass circuit and the brain -- Neurological and cognitive sequelae of cardiac surgery -- Neurocognitive decline following cardiac surgery: incidence, risk factors, prevention, and outcomes -- Neuropathology of brain injury in cardiac surgery -- Biochemical markers of brain injury -- Pitfalls of neuropsychometric assessment and alternative investigative approaches -- Imaging of the brain in cardiac surgery as a tool in brain protection studies -- Current techniques of emboli detection and their utility in brain protection studies -- Intraoperative brain monitoring in cardiac surgery -- Near-infrared spectroscopy monitoring in cardiac surgery: theory, practice, and utility -- The design and methodology of clinical studies on neuroprotection in cardiac surgery -- Temperature and brain protection in cardiac surgery -- Studies of nonpharmacological interventions to reduce brain injury -- Pharmacological studies to reduce brain injury in cardiac surgery -- Off-pump and on-pump coronary artery surgery and the brain -- Experimental basis and clinical studies of brain protection in pediatric heart surgery -- Experimental basis and clinical studies of brain protection in aortic arch surgery -- The future of brain protection in cardiac surgery.
  • Front Matter -- Colour Plates -- Descriptive Aspects. Concept of Schizophrenia: Past, Present, and Future / Nancy C Andreasen -- The Schizophrenia Construct: Symptomatic Presentation / Celso Arango, William T Carpenter -- Child and Adolescent Schizophrenia / Chris Hollis, Judith Rapoport -- Late-Onset Schizophrenia / Robert Howard, Dilip Jeste -- The Schizophrenia Spectrum Personality Disorders / Eran Chemerinski, Larry J Siever -- The Prodrome of Schizophrenia / Jean Addington, Sh̥n W Lewis -- Course and Outcome / Wolfram an der Heiden, Heinz H̃fner -- Neurocognitive Impairments in Schizophrenia: Their Character and Role in Symptom Formation / Terry E Goldberg, Anthony David, James M Gold -- Biological Aspects. The Secondary Schizophrenias / Thomas M Hyde, Maria A Ron -- Schizophrenia: The Epidemiological Horizon / Assen Jablensky, James B Kirkbride, Peter B Jones -- Environmental Risk Factors for Schizophrenia / John J McGrath, Robin M Murray -- Classical Genetic Studies of Schizophrenia / Brien Riley, Kenneth S Kendler -- Genetic Associations in Schizophrenia / Michael C O'Donovan, Michael J Owen -- Intermediate Phenotypes in Genetic Studies of Schizophrenia / Michael F Egan, Tyrone D Cannon -- Electrophysiology of Schizophrenia / Georg Winterer, Robert W McCarley -- Structural Brain Imaging in Schizophrenia and Related Populations / Stephen M Lawrie, Christos Pantelis -- Functional Brain Imaging in Schizophrenia / Andreas Meyer-Lindenberg, Edward T Bullmore -- Neuropathology of Schizophrenia / Paul J Harrison, David A Lewis, Joel E Kleinman -- Neurodevelopmental Origins of Schizophrenia / Daniel R Weinberger, Pat Levitt -- Dopamine and Schizophrenia / Anissa Abi-Dargham, Anthony A Grace -- Contributions of Glutamate and GABA Systems to the Neurobiology and Treatment of Schizophrenia / John H Krystal, Bita Moghaddam -- Animal Models of Schizophrenia / Barbara K Lipska, Joseph A Gogos -- Physical Treatments. Pharmacology and Neuroscience of Antipsychotic Drugs / John L Waddington, Colm M P O'Tuathaigh, Gary J Remington -- Principles of Pharmacological Treatment in Schizophrenia / Thomas R E Barnes, Stephen R Marder -- Comparative Efficacy and Effectiveness in the Drug Treatment of Schizophrenia / John R Geddes, T Scott Stroup, Jeffrey A Lieberman -- Approaches to Treatment-Resistant Patients / Stephan Leucht, Christoph U Correll, John M Kane -- Neurological Complications of Antipsychotic Drugs / Peter M Haddad, Venkata S Mattay -- Metabolic Adverse Effects Associated with Antipsychotic Medications / John W Newcomer, Stefan Leucht -- Psychosocial Aspects. Schizophrenia and Psychosocial Stresses / Paul E Bebbington, Elizabeth Kuipers -- Mental Health Services for Patients with Schizophrenia / Tom Burns, Bob Drake -- Societal Outcomes in Schizophrenia / Iain Kooyman, Elizabeth Walsh -- Psychological Treatment of Psychosis / Gillian Haddock, Will Spaulding -- Economics of the Treatment of Schizophrenia / Nancy H Covell, Susan M Essock, Linda K Frisman -- Index.
  • Brain repair 2006
    Springer
    Cell cycle activation in neurons: the final exit of brain-morpho-dysregulation / Thomas Arendt -- Paved with good intentions: the link between cell cycle and cell death in the mammalian central nervous system / Yan Yang and Karl Herrup -- The role of presenilins in the cell cycle and apoptosis / Mervyn J. Monteiro -- Cell cycle activation and cell death in the nervous system / Zsuzsanna Nagy -- Cell cycle and chromosome segregation defects in Alzheimer's disease / Huntington Potter -- Alzheimer disease: a new beginning or a final exit? / Mark E. Obrenovich ... [et al.] -- From cell cycle activation to the inhibition of the Wnt pathway: a hypothesis of how neurons die in response to b-Amyloid / Agata Copani ... [et al.].
  • The field of brain stimulation is expanding rapidly, with techniques such as DBS, TMS, and tDCS moving from the research community into clinical diagnosis and treatment. Clinical applications include treating disorders such as Parkinson's disease, dystonia, and even depression. The chapters of Brain Stimulation are written by leading international researchers and clinical specialists include coverage of techniques, modes of action and applications in physiology and therapeutics. The combination of research and clinical coverage will be of interest to neurologists, neurosurgeons, psychiatrists, neuroscientists, and health care workers. A comprehensive introduction and overview of deep brain stimulation (DBS)Coverage of DBS, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS)Details the basic science and research utility of DBS and clinical application.
  • Brain Theory From A Circuits And Systems Perspective offers a theory of human consciousness as a natural result of pulsating neurons and synapses within a complex circuit. The book summarizes the electrical, as opposed to the chemical, nature of a brain, and so moves away from customary molecular biology- and biochemistry-focused explanations for consciousness. The book goes beyond the usual structures of artificial neural networks; employing first principles, a particular physical system is synthesized for conscious short term memory, as well as for associative (subconsciously edited) long term memory. It pursues the search for deeper computational power: Where ordinary concepts of logic fail to explain inspired choices concerning artistic appraisal, truth judgment, and understanding, pulsating qubit logic unleashes a fresh avenue for connectivity. Neuroquantology is discussed, including electron tunneling as a regulator of neural actions, and proposed quantum computing within microtubules. This thought provoking work led the author to reveal neurons with qubit properties, or simulated qubits. Simulated qubits do not require a coherent quantum system, and so remain robust for massively parallel controlled toggling and probabilistic computations. Brain Theory From A Circuits And Systems Perspective is supported with physical circuit examples, end-of-chapter exercises, and neuron simulation experiments, and will be valuable to anyone interested in neuro-circuits, neuro-systems and qubits.
  • Brain tumors 2005
    Springer
    Epidemiology of brain tumors / Randa El-Zein, Melissa Bondy, and Margaret Wrensch -- Molecular genetics of tumors of the central nervous system / C. David James -- Molecular pathology of nervous system tumors / Catherine L. Nutt ... [et al.] -- Genetic modeling of glioma formation in mice / Martin Begemann ... [et al.] -- Biology of brain metastasis / Minsoo Kang ... [et al.] -- Analysis of neural precursor cells in the context of origin of brain tumors, their treatment, and repair of treatment-associated damage / Mark Noble and Joerg Dietrich -- Biology of primitive neuroectodermal tumors / John R. Hill, Shoichiro Ohta, and Mark A. Israel -- Molecular and cellular biology of the blood-brain barrier and its characteristics in brain tumors / Helga E. de Vries ... [et al.] -- Immune regulation in the brain : lessons from autoimmunity and implications for brain tumor therapy / Lois A. Lampson -- Genetic pathways in the evolution of gliomas / Hiroko Ohgaki and Paul Kleihues -- DNA damage and repair in the therapeutic response of tumors of the central nervous system / Henry S. Friedman, M. Eileen Dolan, and Francis Ali-Osman -- Role of urokinase-type plasminogen activator receptor in human glioma invasion / Sanjeeva Mohanam and Jasti S. Rao -- Regulation of the cell cycle and apoptosis in human brain tumors / Juan Fueyo, Candelaria Gomez-Manzano, and Timothy J. McDonnell -- Systemic chemotherapy for metastatic tumors of the central nervous system / Charles A. Conrad and W.K. Alfred Yung -- Radiation biology and therapy of tumors of the central nervous system / Nalin Gupta ... [et al.] -- Advances in the management of cerebral metastases / Fadi Hanbali and Raymond Sawaya -- Immunotherapy of central nervous system tumors: contemporary cancer research / Amy B. Heimberger ... [et al.] -- Targeting drugs to tumors of the central nervous system / Maciej S. Lesniak, James Frazier, and Henry Brem -- Rational design and development of targeted brain tumor therapeutics / Francis Ali-Osman ... [et al.].
  • 2011 ClinicalKey
    Meet the increasing need for effective brain tumor management with the highly anticipated revision of Brain Tumors by Drs. Andrew H. Kaye and Edward R. Laws. Over the past decade, enormous advances have been made in both the diagnosis and the surgical and radiotherapeutic management of brain tumors. This new edition guides you through the latest developments in the field, including hot topics like malignant gliomas, functional brain mapping, neurogenetics and the molecular biology of brain tumors, and biologic and gene therapy. You'll also have easy access to the complete contents online, with links to PubMed and a downloadable image library, at www.expertconsult.com. Benefit from the knowledge and experience of Drs. Andrew H. Kaye and Edward R. Laws, globally recognized experts in the field of neurosurgery, as well as many other world authorities.
  • Sect. I Saccadic eye movements / section editor, D.P. Munoz -- 1. Vying for dominance: dynamic interactions control visual fixation and saccadic initiation in the superior colliculus -- 2. Neural control of saccades -- 3. The latency of saccades toward auditory targets in humans -- 4. Contribution of the primate prefrontal cortex to the gap effect -- 5. Influence of stimulus characteristics on the latency of saccadic inhibition -- 6. Commentary: Saccadic eye movements: overview of neural circuitry -- Sect. II. Change blindness and transsaccadic integration / section editor, J. Hyönä -- 7. Converging evidence for the detection of change without awareness -- 8. Blinks, blanks and saccades: how blind we really are for relevant visual events -- 9. Multiple-object permanence tracking: limitation in maintenance and transformation of perceptual objects -- 10. What information survives saccades in the real world? -- 11. Transsaccadic memory of position and form -- 12. Transsaccadic memory for visual object detail -- 13. Commentary: Changes -- Sect. III. Smooth pursuit eye movements / section editors, W. Heide and D.P. Munoz -- 14. Non-target influences on the initiation of smooth pursuit eye movements -- 15. Integration of motion cues for the initiation of smooth pursuit eye movements -- 16. The role of expectancy and volition in smooth pursuit eye movements -- 19 Commentary: Smooth pursuit eye movements: from low-level to high-level vision -- Sect. IV. Eye-hand coordination / section editor, R. Radach -- 20. Cortical frames of reference for eye-hand coordination -- 21. Neuropsychological perspectives on eye-hand coordination in visually-guided reaching -- 22. Visuomotor transformations for eye-hand coordination -- 23. Implications of distracter effects for the organization of eye movements, hand movements, and perception -- 24. Visual short-term memory and motor planning -- 25. Commentary: Coordination of eye and hand in time and space -- Sect. V. Clinical aspects of eye movement research / section editor, W. Heide -- 26. Visual search in long-term cannabis users with early age of onset -- 27. Visual search in patients with left visual hemineglect -- 28. Saccadic adaptation in neurological disorders -- 29. Saccade sequences as markers for cerebral dysfunction following mild closed head injury -- 30. Cognition and the inhibitory control of saccades in schizophrenia and Parkinson's disease -- 31. Control of volitional and reflexive saccades in Tourette's syndrome -- 32. Oculomotor control in a group of very low birth weight (VLBW) children -- 33. A new framework for investigating both normal and abnormal eye movements -- 34. Commentary: Eye movement research with clinical populations -- Subject index.
  • 1. Posttranslational histone modifications and the neurobiology of psychosis -- 2. Epigenetic regulation of GABAergic targets in psychiatry -- 3. Possible roles of DNA methylation in bipolar disorder -- 4. The epigenetics of depression and suicide -- 5. Epidemiology research adn epigenetics: translational epidemiology of schizophrenia -- 6. Environmental studies as a tool for detecting epigenetic mechanisms in schizophrenia -- 7. Imprinting, inactivation and the behavioural genetics of the X chromosomes -- 8. The strategies of the genes: genomic conflicts, attachment theory, and development of the social brain -- 9. Genomic imprinting effects on brain and behavior: future directions -- 10. Epigenetic influence of the social environment -- 11. Toward an understanding of the dynamic interdependence of genes and environment in the regulation of phenotype -- 12. Histone deacetylase inhibitors: a novel therapeutic approach for cognitive disorders -- 13. Epigenetic mechanisms of memory consolidation -- 14. Epigenetic methanisms in memory formation.
  • 1. Brain structures and consciousness -- 2. Binding problem of consciousness -- 3.Consciousness and functional connectivity -- 4. Binding problem and dissociated mind -- 5. The unconscious mind -- 6. Mind and space -- 7. The universe within.
  • A. Introduction / Harry Whitaker, C.U.M. Smith, and Stanley Finger -- Chronology / C.U.M. Smith -- B. Background. Introduction / The editors -- Brain and mind in the 'long' eighteenth century / C.U.M. Smith -- Enlightening neurosciences : microscopes and microscopy in the eighteenth century / Brian J. Ford -- Corpus curricula : medical education and the voluntary hospital movement / Jonathan Reinarz -- Some thoughts on the medical milieu in the last quarter of the eighteenth century as reflected in the life and activities of James Parkinson (1755-1824) / Christopher Gardner-Thrope -- C. The nervous system. Introduction / The editors -- John Hunter's contribution to neuroscience / James L. Stone, James T. Goodrich, and George R. Cybulski -- William Cullen (1710-1790) and Robert Whytt (1714-1766) on the nervous system / Julius Rocca -- 1710 : the introduction of experimental nervous system physiology and anatomy by François Pourfour du Petit / Lawrence Kruger and Larry W. Swanson -- Irritable glue: the Haller-Whytt controversy on the mechanism of muscle contraction / Eugenio Frixione -- The taming of the electric ray : from an wonderful and dreadful "art" to "animal electricity" and "electric battery" / Marco Piccolino -- Luigi Galvani, physician, surgeon, physicist: from animal electricity to electro-physiology / Miriam Focaccia and Raffaella Simili -- D. Brain and behavior. Introduction / The editors -- The vision of William Porterfield / Nicholas J. Wade -- David Hartley's neural vibrations and psychological associations / Robert B. Glassman and Hugh W. Buckingham -- Charles Bonnet's neurophilosophy / Harry A. Whitaker and Yves Turgeon -- Swedenborg and localization theory / Ulf Norrsell -- E. Medical theories and applications. Introduction / The editors -- Neuroscience in the work of Boerhaave and Haller / Peter J. Koehler -- Apoplexy : changing concepts in the eighteenth century / Catherine E. Storey -- Benjamin Franklin and the electrical cure for disorders of the nervous system / Stanley Finger -- Gentleman's magazine, the advent of medical electricity, and disorders of the nervous system / Hannah Sypher Locke and Stanley Finger -- Therapeutic attractions: early applications of electricity to the art of healing / Paola Bertucci -- John Wesley on the estimation and cure of nervous disorders / James G. Donat -- Franz Anton Mesmer and the rise and fall of animal magnetism : dramatic cures, controversy, and ultimately a triumph for the scientific method / Douglas J. Lanska and Joseph T. Lanska -- Hysteria in the eighteenth century / Diana Faber -- F. Cultural consequences. Introduction / The editors -- Technological metaphors and the anatomy of representations in eighteenth-century French materialism and dualist mechanism / Timo Kaitaro -- Explorations of the brain, mind and medicine in the writings of Jonathan Swift / Marjorie Perlman Lorch -- Temperament and the long shadow of nerves in the eighteenth century / George Rousseau.
  • Chapter 1. Nerve cells and synapses -- Chapter 2. Central nervous system basics- the brain and spinal cord -- Chapter 3. A map of the brain -- Chapter 4. Peripheral nerves -- Chapter 5. Command and control- the motor systems -- Chapter 6. Gathering information- the sensory systems -- Chapter 7. The human cerebral cortex -- Chapter 8. Higher level functions consciousness, learning, memory, and emotions -- Chapter 9. When things go wrong- brain disease and injury -- Chapter 10. The development of the brain and spinal cord -- Chapter 11. Techniques for studying the brain.
  • Brainstem disorders 2011
    Springer
  • In recent years, the advent of MRI technology seems to have unlocked the secrets of the human mind, revealing the sources of our deepest desires, intentions, and fears. In this book, the authors argue that the explanatory power of brain scans in particular and neuroscience more generally has been vastly overestimated. Although acknowledging its tremendous potential, they believe that the overzealous application of the burgeoning field of brain science has put innocent people in jail, prevented addicts from healing themselves, and undermined notions of free will and responsibility.
  • pt. 2 ScienceDirect
  • Overview -- Diagnostic studies -- Neurologic symptoms -- Direct complications of cancer -- Indirect complications of cancer -- Complications of cancer therapy -- Neurologic complications of specific malignancies.
  • This book provides the practicing physician with a practical approach to the diagnosis, evaluation, and management of headache disorders based on lessons learned from real-life headache patients. Internationally well-known headache experts present cases from their own practice and discuss the evaluation and management of each case step by step. The clearly structured chapters cover initial evaluation and diagnostic work-up, imaging, differential diagnosis, interpretation of findings of further work-up, treatment options and response and key points. A wide spectrum of headache types is covered, including both primary and secondary headache disorders. The reader will learn how to diagnose and manage different headache disorders directly from the clinical experience of experts. Case-Based Diagnosis and Management of Headache Disorders will be of value for neurologists and a wide range of physicians - from those in other specialties to primary care givers.
  • PART I. Aneurysms and Subarachnoid Hemorrhage -- CASE 1. Embolization of a Ruptured Basilar Tip Aneurysm -- CASE 2. Embolization of a Ruptured Anterior Communicating Artery Aneurysm -- CASE 3. Multiple Aneurysms in a Patient with Subarachnoid Hemorrhage -- CASE 4. Management of an Unruptured Internal Carotid Artery Aneurysm -- CASE 5. Balloon-Assisted Embolization of a Ruptured Wide-Necked Anterior Communicating Artery Aneurysm -- CASE 6. Stent-Assisted Embolization of a Wide-Necked Recurrent Posterior Communicating Artery Aneurysm -- CASE 7. Management of Complications during Aneurysm Coiling: Proximal Mechanically Induced Vasospasm -- CASE 8. Management of Complications during Aneurysm Coiling: Periprocedural Aneurysm Rupture -- CASE 9. Management of Complications during Aneurysm Coiling: Periprocedural Thrombus Formation -- CASE 10. Management of Subarachnoid Hemorrhage-Induced Vasospasm -- CASE 11. Management of Giant “Partially Thrombosed” Aneurysms -- CASE 12. Embolization of a Dissecting Vertebral Artery Aneurysm -- CASE 13. Embolization of a Dissecting Distal Anterior Inferior Cerebellar Artery Aneurysm -- CASE 14. Embolization of an Infectious Distal Middle Cerebral Artery Aneurysm -- PART II. Brain Arteriovenous Malformations -- CASE 15. Arterial Embolization of an Unruptured Pial Arteriovenous Malformation -- CASE 16. Partial Targeted Embolization of an Unruptured Pial Arteriovenous Malformation -- CASE 17. Pre-radiosurgical Embolization of an Unruptured Pial Arteriovenous Malformation -- CASE 18. Embolization of an Acutely Ruptured Arteriovenous Malformation with Intranidal Aneurysm -- CASE 19. Management of Hydrocephalus in an Unruptured Pial Arteriovenous Malformation -- CASE 20. Embolization of a Pial Fistulous Arteriovenous Malformation -- CASE 21. Partial Embolization of a Choroidal Fistulous Arteriovenous Malformation -- CASE 22. Embolization of a Microshunt into a Developmental Venous Anomaly -- PART III. Cranial Dural Arteriovenous Shunts -- CASE 23. Arterial Embolization of a Lateral Epidural Type of Dural Arteriovenous Fistula -- CASE 24. Arterial Embolization of an Ethmoidal Dural Arteriovenous Fistula -- CASE 25. Transarterial Embolization of a Transverse Sinus Dural Arteriovenous Fistula -- CASE 26. Transvenous Embolization of a Transverse Sinus Dural Arteriovenous Fistula -- CASE 27. Transvenous Embolization through Thrombosed Dural Sinus of an Aggressive Transverse Sinus Dural Arteriovenous Fistula at the Level of an Isolated Dural Sinus -- CASE 28. Transvenous Embolization of a Condylar Confluence Dural Arteriovenous Fistula -- CASE 29. Transvenous Embolization of a Cavernous Sinus Dural Arteriovenous Fistula -- CASE 30. Multiple Dural Arteriovenous Fistulae -- PART IV. Head and Neck Vascular Lesions -- CASE 31. Transarterial Embolization of a Mandibular Arteriovenous Fistula -- CASE 32. Combined Direct Puncture and Transarterial Embolization of a Scalp Arteriovenous Malformation -- CASE 33. Percutaneous Puncture of a Facial Venous Vascular Malformation with Injection of Bleomycin -- CASE 34. Percutaneous Puncture of a Facial Venous Malformation with Injection of Alcohol -- CASE 35.Transarterial Particle Embolization of a Facial Hemangioma -- PART V. Tumors -- CASE 36. Preoperative Transarterial Particle Embolization of a Meningioma -- CASE 37. Preoperative Transarterial Particle Embolization of a Juvenile Angiofi broma -- CASE 38. Preoperative Embolization of a Carotid Body Tumor -- CASE 39. Preoperative Embolization of a Recurrent Temporal Paraganglioma -- CASE 40. Preoperative Transarterial Embolization of a Spinal Hemangioblastoma -- CASE 41. Preoperative Embolization of a Hypervascular Vertebral Body Metastasis -- PART VI .Trauma -- CASE 42. Balloon Embolization of a Traumatic Carotid-Cavernous Fistula -- CASE 43. Coil Embolization of a Traumatic Carotid-Cavernous Fistula -- CASE 44. Carotid Artery Blowout -- CASE 45. Balloon Occlusion Test of a Traumatic Internal Carotid Artery Aneurysm Treated by Internal Carotid Artery Sacrifice with Detachable Balloons -- CASE 46. Transarterial Particle Embolization for Epistaxis -- PART VII. Stroke -- CASE 47. Intra-arterial rtPA Thrombolysis in Acute Ischemic Stroke -- CASE 48. Mechanical Thrombolysis in Acute Stroke with an Aspiration Device -- CASE 49. Mechanical Thrombectomy in Acute Stroke with a Retrievable Stent -- CASE 50. Stent-Assisted Angioplasty of a Symptomatic Extracranial Internal Carotid Artery Stenosis -- CASE 51. Stenting of a Symptomatic Post-surgical Internal Carotid Artery Stenosis -- CASE 52. Intracranial Revascularization with a Self-Expandable Stent -- CASE 53. Balloon-Mounted Intracranial Stenting of a High-Grade Vertebral Artery Stenosis -- CASE 54. Subclavian Steal Syndrome -- CASE 55. Direct Thrombolysis of Cerebral Venous Sinus Thrombosis -- PART VIII. Pediatric Vascular Interventions -- CASE 56. Transarterial Embolization of a Vein of Galen Aneurysmal Malformation -- CASE 57. Embolization of a Pial Arteriovenous Fistula in a Patient with Hereditary Hemorrhagic Telangiectasia -- CASE 58. Management of Pediatric Cerebral Aneurysm -- CASE 59. Transarterial Embolization of a Dural Sinus Malformation -- PART IX. Spine Vascular Interventions -- CASE 60. Spinal Dural Arteriovenous Fistulae: Successful Arterial Embolization -- CASE 61. Spinal Dural Arteriovenous Fistulae: Unsuccessful Arterial Embolization -- CASE 62. Spinal Arteriovenous Malformation of the Fistulous Type: Treatment with Liquid Embolic Material -- CASE 63. Spinal Arteriovenous Malformation of the Fistulous Type: Treatment with Coils -- CASE 64. Spinal Arteriovenous Malformation of the Glomerular or Nidus Type: Treatment withLiquid Embolic Material -- CASE 65. Balloon Embolization of a Vertebrovertebral Fistula -- PART X. Spine Percutaneous Interventions [p.393] CASE 66 Fluoroscopy-Guided Percutaneous Vertebral Biopsy -- CASE 67. Percutaneous Vertebroplasty in Osteoporotic Vertebral Compression Fracture -- CASE 68. Balloon-Assisted Kyphoplasty in Osteoporotic Vertebral Compression Fracture -- CASE 69. Multilevel Kyphoplasty in Multiple Myeloma -- CASE 70. Radiofrequency Kyphoplasty in an Osteoporotic Vertebral Compression Fracture -- CASE 71. Radiofrequency Kyphoplasty in Multiple Myeloma [p.426] CASE 72 Intra-articular Facet Joint Block -- Index.
  • Cat primary visual cortex 2002
    ScienceDirect
    The concept of cat primary visual cortex / Bertram R. Payne and Alan Peters -- Optical imaging of functional architecture in cat primary visual cortex / Mark Hubener and Tobias Bonhoeffer -- 2-Deoxyglucose architecture of cat primary visual cortex / Siegrid Lowel -- Functional mapping in the cat primary visual cortex using high magnetic fields / Dae-Shik Kim, Timothy Q. Duong, Kamil Ugurbil, and Seong-Gi Kim -- Relationships of LGN afferents and cortical efferents to cytochrome oxidase blobs / Joanne A. Matsubara and Jamie D. Boyd -- Influence of topography and ocular dominance on the functional organization of callosal connections in cat striate cortex / Jaime F. Olavarria -- Essential and sustaining LGN inputs to cat primary visual cortex / Theodore G. Weyand -- Integration of thalmic inputs to cat primary visual cortex / R. Clay Reid, Jose-Manuel Alonso, and W. Martin Usrey -- The emergence of direction selectivity in cat primary visual cortex / Allen L. Humphrey and Alan B. Saul -- Long-range intrinsic connections in cat primary visual cortex / Kerstin E. Schmidt and Siegrid Lowell -- Pharmacological studies on receptive field architecture / Ulf T. Eysel -- Orientation selectivity and its modulation by local and long-range connections in visual cortex / David Somers, Valentin Dragoi, and Mriganka Sur -- Response synchronization, gamma oscillations, and perceptual binding in cat primary visual cortex / Wolf Singer -- The special relationship between B Retinal ganglion cells and cat primary visual cortex / Bertram R. Payne and R. Jarrett Rushmore -- Primary visual cortex within the cortico-cortico-thalmic network / Jack W. Scannell and Malcolm P. Young -- Behavioral analyses of the contributions of cat primary visual cortex to vision / Donald E. Mitchell -- Index.
  • A comprehensive overview of the basic science and current clinical knowledge on cavernous malformations of the brain and spinal cord. Cavernous Malformations of the Brain and Spinal Cord begins by covering general aspects of the disease, including the natural history, molecular biology, pathological processes, genetic basis, neuroradiology, and classification of cavernous malformations. Separate chapters then address the various types of cavernous malformations, thoroughly describing the clinical presentation and management approaches for each clinical situation. Incisive review of recent literature sheds light on topics of incidence, location, and outcomes. Neurosurgeons, neurologists, and neuroradiologists, especially those caring for patients with seizures and hemorrhagic stroke, will benefit from the information in this complete reference.
  • Methodological considerations in the evaluation of cell cycle in the central nervous system / Richard A. Prayson -- Neural stem cells / Philippe Taupin -- Progenitors and precursors of neurons and glial cells / Monika Bradl -- Vaculogenesis and angiogenesis / Gerald A. Grant and Damir Janigro -- Neuronal migration and malformation of cortical development / Giorgio Battaglia and Stefania Bassanini -- Genome-wide expression profiling of neurogenesis in relation to cell cycle exit / P. Roy Walker ... [et al.] -- Neurogenesis and apoptotic cell death / Klaus van Leyen ... [et al.] -- Ion channels and cell cycle / Annarosa Arcangeli and Andrea Becchetti -- Nonsynaptic GABAergic communication and postnatal neurogenesis / Xiuxin Liu, Anna Bolteus, and Angélique Bordey -- Critical roles of Ca2+ and K+ homeostasis in apoptosis / Shan Ping Yu -- Mammalian neural stem-cell renewal / Yvan Arsenijevic -- Methods of determining apoptosis in neuro-oncology: review of the literature / Brian T. Ragel ... [et al.] -- Cell cycle, neurological disorders, and reactive gliosis / Kerri L. Hallene and Damir Janigro -- Potassium channels, cell cycle and tumorigenesis in the central nervous system / Gabriele Dini, Erin V. Ilkanich, and Damir Janigro -- Enhanced neurogenesis following neurological disease / Philippe Taupin -- Endothelial injury and cell cycle re-entry / Ljiliana Krizanac-Bengez -- The contribution of bone marrow-derived cells to cerebrovascular formation and integrity / David Kobiler and John Glod -- Microvessel remodeling in cerebral ischemia / Danica B. Stanimirovic, Maria J. Moreno, and Arsalan S. Haqqani -- Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders / Lieve Moons, Peter Carmeliet, and Mieke Dewerchin -- Epidermal growth factor receptor in the adult brain / Carmen Estrada and Antonio Villalobo -- Neurodegeneration and loss of cell cycle control in postmitotic neurons / Randall D. York, Samantha A. Cicero, and Karl Herrup -- Cell cycle activation and the amyloid-[beta] protein in Alzheimer's disease / Katarzyna A. Gustaw ... [et al.] -- Neuronal precursor proliferation and epileptic malformations of cortical development / Jorge A González-Martínez, William E. Bingaman, and Imad M. Najm -- Vascular differentiation and cell cycle / Luca Cucullo -- Adult neurogenesis and central nervous system cell cycle analysis: novel tools for exploration of the neural causes and correlates of psychiatric disorders / Amelia J. Eisch and Chitra D. Mandyam -- Neurogenesis and Alzheimer's disease: compensation, crisis, or chaos? / Gemma Casadesus ... [et al.] -- P53 and multidrug resistance transporters in the central nervous system / Shirley Teng and Micheline Piquette-Miller -- Signaling modules in glial tumors and implications for molecular therapy / Gurpreet S. Kapoor and Donald M. O'Rourke -- Detection of proliferation in gliomas by positron emission tomography imaging / Alexander M. Spence ... [et al.] -- Transition of normal astrocytes into a tumor phenotype / Sean E. Aeder and Isa M. Hussaini -- Mechanisms of gliomagenesis / Wei Zhang and Howard A. Fine -- Cell cycle of encapsulated cells / Roberto Dal Toso and Sara Bonsiegna -- Viral vector delivery to dividing cells / Yoshinaga Saeki -- Electrical stimulation and angiogenesis: electrical signals have direct effects on endothelial cells / Min Zhao -- Development and potential therapeutic aspects of mammalian neural stem cells / L. Bai, S.L. Gerson, and R.H. Miller -- Mammalian Sir2 proteins: a role in epilepsy and ischemia / Barbara Aumayr and Damir Janigro.
  • Current views of the embryonic and neural stem cell : cell replacement or molecular repair? / Roya Sabetrasekh ... [et al.] -- Developing novel cell sources for transplantation in Parkinson's disease / Nicolaj S. Christophersen ... [et al.] -- Neural transplantation in the nonhuman primate model of Parkinson's disease / Kimberly B. Bjugstad and John R. Sladek, Jr. -- Cell-based therapy for Huntington's disease / Claire M. Kelly, Stephen B. Dunnett, and Anne E. Rosser -- Use of bone marrow stem cells as therapy for behavioral deficits in rodent models of Huntington's disease / Gary L. Dunbar, Justin D. Oh-Lee, and Laurent Lescaudron -- Human neuroteratocarcinoma cells as a neural progenitor graft source for cell transplantation in stroke / Cesario V. Borlongan ... [et al.] -- Therapeutic applications of bone marrow-derived stem cells in neurologic injury and disease / C. Dirk Keene ... [et al.] -- Cell therapy for models of pain and traumatic brain injury / Mary Eaton and Jacqueline Sagen -- The use of sertoli cells in neural transplantation / Dwaine F. Emerich, Cesario V. Borlongan, and Craig Halberstadt -- The choroids plexus : a novel graft source for neural transplantation / Cesario V. Borlongan ... [et al.] -- Progress and challenges in immunoisolation for CNS cell therapy / Christopher G. Thanos and Dwaine F. Emerich -- Evidence-based methodology for advancing neural reconstruction / Stephen Polgar -- Hematopoietic cell therapy for brain repair / Martina Vendrame and Alison E. Willing -- Stem cells and regenerative medicine : commercial and pharmaceutical implications / L. Eduardo Cruz and Silvia P. Azevedo.
  • Stroke remains one of the main causes of death and disability worldwide. Effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.
  • Age-related macular degeneration: clinical findings, histopathology, and imaging techniques / Zarbin, M.A.; Casaroli-Marano, R.P.; Rosenfeld, P.J. -- General pathophysiology in retinal degeneration / Wert, K.J.; Lin, J.H.; Tsang, S.H. -- Juvenile-onset macular degeneration and allied disorders / North, V.; Gelman, R.; Tsang, S.H. -- Diagnosis and complementary examinations / Menghini, M.; Duncan, J.L. -- Stem cells for retinal repair / Stern, J.; Temple, S. -- Differentiation of pluripotent stem cells into retinal pigmented epithelium / Croze, R.H.; Clegg, D.O. -- Neural retinal regeneration with pluripotent stem cells / Ramsden, C.M.; Powner, M.B.; Carr, A.-J.F.; Smart, M.J.K.; da Cruz, L.; Coffey, P.J. -- Stem cells, retinal ganglion cells and glaucoma / Sluch, V.M.; Zack, D.J. -- Stem cells : immunology and immunomodulation / Tena, A.; Sachs, D.H. -- Biochemical restoration of aged human Bruch's membrane : experimental studies to improve retinal pigment epithelium transplant survival and differentiation / Sugino, I.K.; Sun, Q.; Cheewatrakoolpong, N.; Malcuit, C.; Zarbin, M.A. -- Approaches to cell delivery : substrates and scaffolds for cell therapy / Kundu, J.; Michaelson, A.; Baranov, P.; Young, M.J.; Carrier, R.L. -- Microdevice-based cell therapy for age-related macular degeneration / Lu, B.; Tai, Y.-C.; Humayun, M.S. -- Cell and gene therapy / Rao, R.C.; Zacks, D.N. -- Cellular manufacturing for clinical applications / Sheu, J.; Klassen, H.; Bauer, G. -- Regulatory issues in cell-based therapy for clinical purposes / Casaroli-Marano, R.P.; Tabera, J.; Vilarrodona, A.; Trias, E.
  • Cell cycle activation in neurons: the final exit of brain-morpho-dysregulation / Thomas Arendt -- Paved with good intentions: the link between cell cycle and cell death in the mammalian central nervous system / Yan Yang and Karl Herrup -- The role of presenilins in the cell cycle and apoptosis / Mervyn J. Monteiro -- Cell cycle activation and cell death in the nervous system / Zsuzsanna Nagy -- Cell cycle and chromosome segregation defects in Alzheimer's disease / Huntington Potter -- Alzheimer disease-a new beginning or a final exit? / Mark E. Obrenovich ... [et al.] -- From cell cycle activation to the inhibition of the WNT pathway: a hypothesis of how neurons die in response to B-Amyloid / Agata Copani ... [et al.].
  • Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches. Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians.
  • The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components developFeatures leading experts in various subfields as Section Editors and article AuthorsAll articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarshipVolume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity.
  • Introduction : homeostasis and cellular physiology -- Diffusion and permeability -- Osmotic pressure and water movement -- Electrical consequences of ionic gradients -- Ion channels -- Passive electrical properties of membranes -- Generation and propagation of the action potential -- Ion channel diversity -- Electrochemical potential energy and transport processes -- Passive solute transport -- Active transport -- Synaptic physiology I -- Synaptic physiology II -- Molecular motors and the mechanism of muscle contraction -- Excitation-contraction coupling in muscle -- Mechanics of muscle contraction.
  • Respiration is one of the most basic motor activities crucial for survival of the individual. It is under total control of the central nervous system, which adjusts respiratory depth and frequency depending on the circumstances the individual finds itself. For this reason this volume not only reviews the basic control systems of respiration, located in the caudal brainstem, but also the higher brain regions, that change depth and frequency of respiration. Scientific knowledge of these systems is crucial for understanding the problems in the many patients suffering from respiratory failure.
  • "The field of critical care medicine is in the midst of a dramatic change. Technological and scientific advances during the last decade have resulted in a fundamental change in the way we view disease processes, such as sepsis, shock, acute lung injury, and traumatic brain injury. Pediatric intensivists have been both witness to and active participants in bringing about these changes and it is imperative that all physicians caring for critically ill children in this new era have a thorough understanding of the applicability of these modern developments to the care of patients at the bedside and to keep up with the rapidly evolving field of critical care medicine. Neurologic emergencies are a common reason for admission to the pediatric intensive care unit (PICU). A thorough understanding of the diseases and disorders affecting the pediatric central nervous system is vital for any physician or health care provider working in the PICU. The Central Nervous System in Pediatric Critical Illness and Injury has been written by an international panel of experts to provide readers with an in-depth discussion on the resuscitation, stabilization, and ongoing care of the critically ill or injured child with central nervous system dysfunction. This book is therefore absolutely crucial for anyone working in the PICU, from physicians, residents and fellows in critical care, neurology, and pediatrics to specialist nurses and support personnel on the PICU and all medical professionals who are involved in the management of these patients."--Publisher's website.
  • The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. Central Nervous System Intraoperative Cytopathology covers the full spectrum of benign and malignant conditions of the CNS with emphasis on common disorders. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. Central Nervous System Intraoperative Cytopathology is a valuable quick reference for pathologists, cytopathologists, and fellows and trainees dealing with this exigent field.
  • Introduction to brain metastasis / Diane Palmieri -- Molecular biology of brain metastasis / Stephan Woditschka ... [et al.] -- Brain microenvironment / Mami Noda -- Vascular permeability within brain metastases / Chris E. Adkins ... [et al.] -- Imaging experimental brain metastases / Amanda M. Hamilton and Paula J. Foster -- Possibilities of targeted therapies for brain metastasis / Frank Winkler -- Surgery for brain metastasis / Douglas L. Stofko, Robert J. Weil, and Steven A. Toms -- Is there a role for systemic chemotherapy in the treatment of brain metastases / Marc C. Chamberlain -- Radiation therapy of CNS metastases / DeeDee Smart -- Leptomeningeal metastasis / Priscilla K. Brastianos, Charilaos H. Brastianos, and April F. Eichler -- Quality of life with CNS metastasis / Lauren A. Chandler and Kathleen L. Fuchs.
  • Cerebellar learning 2014
    ScienceDirect
    Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biologi
  • This revised and enlarged edition of Cerebral Angiography, which includes new angiographic studies and illustrative drawings, offers detailed guidance on diagnostic use of the procedure. The first part of the book describes the normal anatomy of the cerebral arteries and veins, with attention to morphological aspect, embryological development, function, and vascular territories. The intraorbital and extracranial vascularization is also considered. The reader will gain a sound knowledge of normal vascular anatomy and its variations that will serve as a basis for the correct interpretation of pathological processes and their clinical significance, as covered in the second part of the book. Among the pathologies considered are vascular abnormalities, including angiomas, fistulas and aneurysms; atherosclerotic and non-atherosclerotic stenosis and occlusion of the cerebral vessels; venous thrombosis; intraorbital and extracranial vascular malformations. Pathogenesis, morphological and dynamic aspects, responsible for clinical symptoms and influencing the therapy are described. While the emphasis throughout is on the diagnostic value of cerebral angiography, many examples of endovascular treatment in different pathological situations are also presented, with discussion of indications, risks and results.
  • Historical Perspectives in Understanding Traumatic Brain Injury and in Situating Disruption in CBF in the Pathotrajectory of Head Trauma / Christopher Betrus and Christian W. Kreipke -- Situating Cerebral Blood Flow in the Pathotrajectory of Head Trauma / Justin Graves, Christopher Betrus and Jose A. Rafols -- Modeling of Traumatic Brain Injury and its Implications in Studying the Pathology of Repeated Mild Impacts to the Head / Michael J. Kane, Mariana Angoa Pérez, Denise I. Briggs, David C. Viano and Christian W. Kreipke, et al. -- The Presence of Venous Damage and Microbleeds in Traumatic Brain Injury and the Potential Future Role of Angiographic and Perfusion Magnetic Resonance Imaging / E. M. Haacke, Waqar Raza, Bo Wu and Zhifeng Kou -- Situating the Endothelin System in the Pathotrajectory of TBI-Induced Changes in Hemodynamics / Anthony Kropinski, Paula Dore-Duffy and Christian W. Kreipke -- Age and Sex Differences in Cerebral Blood Flow and Autoregulation after Pediatric Traumatic Brain Injury / William M. Armstead and Monica S. Vavilala -- New Frontiers in Clinical Trials Aimed at Improving Outcome Following Traumatic Brain Injury / Christian W. Kreipke, Anthony Kropinski, Justin Graves, David Tiesma and Michael Kaufman, et al.
  • Cerebral hemorrhage 2008
    Springer
  • Cerebral palsy 2005
    Springer
  • This is a thought-provoking book which introduces a new way of thinking on the development and use of interventions. Relevant to current practice, it advocates early, targeted activity that is focused on increasing muscle activation, training basic actions and minimizing (or preventing) mal-adaptive changes to muscle morphology and function. The authors present recent scientific findings in brain science, movement sciences (developmental biomechanics, motor control mechanisms, motor learning, exercise science) and muscle biology. This knowledge provides the rationale for active intervention, underpinning the need for an early referral to appropriate services. The book features methods for promoting relatively intensive physical activity in young infants without placing a burden on parents which include assistive technologies such as robotics, electronic bilateral limb trainers and baby treadmills. This book begins by specifying the guidelines for training and exercise, outlining the rationale for such intervention. It goes on to cover the fundamentals of neuromotor plasticity and the development and negative effects of limited motor activity on brain organization and corticospinal tract development. Neuromuscular adaptations to impairments and inactivity are discussed along with the General Movement assessment that can provide early diagnosis and prognosis, facilitating very early referral from paediatric specialists to training programs. The book ends with a section featuring various methods of training with the emphasis on preventing/minimizing muscle contracture, stimulating biomechanically critical muscle activity and joint movement.
  • Section 1. Cerebral hemodynamics and cerebrovascular imaging -- section 2. EC-IC bypass surgical techniques -- section 3. Cerebral ischemia -- section 4. Giant cerebral aneurysms -- section 5. Skull base tumors.
  • The book contains 48 articles presented at the 11th International Conference on Cerebral Vasospasm held in Cincinnati, Ohio, USA, in July 2011. This collection of papers represents a cross-section of the enormous progress that has been made towards a thorough understanding and effective treatment of neurovascular events following aneurysmal subarachnoid hemorrhage, including cerebral vasospasm. It is of interest to clinicians who wish to apply state-of-the-art knowledge to their management of this devastating condition and to basic scientists wishing to expand their understanding of cerebrovascular and neural pathophysiology related to subarachnoid hemorrhage.
  • The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.
  • Part 1. Brain plasticity across the lifespan. Chapter 1. Balancing plasticity/stability across brain development / Anne E. Takesian, Takao K. Hensch. Chapter 2. Brain plasticity in the developing brain / Bryan Kolb, Richelle Mychasiuk, Arif Muhammad, Robbin Gibb. Chapter 3. Cortical plasticity, excitatory-inhibitory balance, and sensory perception / Iona Carcea, Robert C. Froemke. Chapter 4. Changes in plasticity across the lifespan : cause of disease and target for intervention / Lindsay Oberman, Alvaro Pascual-Leone. Chapter 5. What does it take to show that a cognitive training procedure is useful? : a critical evaluation / Nori Jacoby, Merav Ahissar. Chapter 6. Principles of neuroplasticity-based rehabilitation / Mor Nahum, Hyunkyu Lee, Michael M. Merzenich -- Part 2. Brain plasticity-based therapies for the treatment of developmental disorders. Chapter 7. Fast ForWord® : the birth of the neurocognitive training revolution / Paula Tallal. Chapter 8. Music training for the development of reading skills / Adam Tierney, Nina Krauss. Chapter 9. Mechanisms of plasticity in the developing and adult visual cortex / Mriganka Sur, Ikue Nagakura, Naiyan Chen, Kiroki Sugihard. Chapter 10. Brain mechanisms of plasticity in response to treatments for core deficits in autism / Pamela E. Ventola, Devon Oosting, Laura C. Anderson, Kevin A. Pelphrey -- Part 3. Brain plasticity-based therapeutics for the treatment of clinical indications in the adult brain. Chapter 11. Targeting plasticity with vagus nerve stimulation to treat neurological disease / Seth A. Hays, Robert L. Rennaker, Michael P. Kilgard. Chapter 12. Computerized cognitive training targeting brain plasticity in schizophrenia / Bruno Biagianti, Sophia Vinogradov. Chapter 13. The nonspacial side of spacial neglect and related approaches to treatment / Thomas M. Van Vleet, Joseph M. DeGutis. Chapter 14. A cognitive framework for understanding and improving interference resolution in the brain / Jyoti Mishra, Joaquin A. Anguera, David A. Ziegler, Adam Gazzaley. Chapter 15. Constraint-induced movement therapy : a method for harnessing neuroplasticity to treat motor disorders / Gitendra Uswatte, Edward Taub/ Chapter 16. Novelty interventions to enhance broad cognitive abilities and prevent dementia : synergistic approaches for the facilitation of positive plastic change / Patrick Fissler, Olivia Küster, Winfried Schlee, Iris-Tatjana Kolassa. Chapter 17. Decoding speech for understanding and treating aphasia / Brian N. Pasley ; Robert T. Knight.
  • Missing Links in the Evolution of Language -- Consciousness as a Decision to Engage -- Thinking About Brain and Consciousness -- The Global Neuronal Workspace Model of Conscious Access: From Neuronal Architectures to Clinical Applications -- Disorders of Consciousness: What Do We Know? -- When Thoughts Become Actions: Imaging Disorders of Consciousness -- Rhythmic Neuronal Synchronization Subserves Selective Attentional Processing -- Studying Consciousness Using Direct Recording from Single Neurons in the Human Brain -- Intrinsic Activity and Consciousness -- Beyond Libet: Long-Term Prediction of Free Choices from Neuroimaging Signals --Subliminal Motivation of the Human Brain -- From Conscious Motor Intention to Movement Awareness.
  • Genius and dilettantism often go hand in hand. Nowhere is this truer than in the life of Charles-Edouard Brown-Sequard, the bilingual physician and neurologist who succeeded Claude Bernard as the Chair of Experimental Medicine at the College de France in Paris after having practiced in Paris, London and in the USA, especially in Harvard. For most men, making one discovery of global importance would have sufficed to satisfy their curiosity and self-image. Not so Brown-Sequard. His explanation of the neurological disparity following the hemi-section of the spinal cord was a unique achievement that added his name to the syndrome and made him immortal. Yet, the demons of his mind tormented him in his endless search for medical truths and drove him to explore other phenomena, seeking to explain and remedy them. This unique biography shows for the first time the conflict between his professional and personal life, and should appeal to all students of medical history and psychology.
  • "Written for Pain Management Practitioners, Oncologists, Oncology Nurses, Nurse Practitioners, Social Workers, Pharmacologists, and Primary Care Practitioners, as well as students in these fields, this reference provides insight into chemotherapy-induced neuropathic pain cancer survivors suffer. It reviews the basic and clinical research into the normal physiology of pain transmission pathways, neuropathic pain pathology, the chemotherapeutic drug mechanisms of action and adverse effects, chemotherapy-induced neuropathy, and drug discovery efforts for treatment. Bridging the gap between theory and practice, this reference covers both basic science and clinical research, providing a unique insight into drug discovery efforts"--Provided by publisher.
  • "Once an uncommon clinical finding, the Chiari malformations are now frequently seen with the advent of more sophisticated imaging modalities. With more than one hundred years of experience with these entities, medicine currently has a much better understanding of the embryology and pathophysiology of the disorder. Long-term outcome studies are becoming more prevalent and patients are commonly operated on with generally favorable results. Comprehensive in design, the The Chiari malformations focuses on the two most common forms of hindbrain herniation, the Chiari I and II malformations. Since the original description and classification of hindbrain hernias more than one hundred and twenty years ago, the Chiari malformations have revealed much of their pathophysiology and have become easily diagnosed radiologically. Indeed with the availability of MRI, more and more patients are being labeled with the diagnosis but without symptoms or appropriate symptoms. Timely and an invaluable addition to the literature, The Chiari malformations thoroughly details the progress that has been made with our understanding of these conditions, their radiologic definition, details of operative intervention and prediction of outcome"-- From publisher's website.
  • Inherited metabolic diseases of the nervous system / John H. Menkes and William R. Wilcox -- Mitochondrial encephalomyopathies / Harvey B. Sarnat and John H. Menkes -- Heredodegenerative diseases / John H. Menkes -- Chromosomal anomalies and contiguous-gene syndromes / John H. Menkes and Rena E. Falk -- Neuroembryology, genetic programming, and malformations of the nervous system / Harvey B. Sarnat ... [et al.] -- Perinatal asphyxia and trauma / John H. Menkes and Harvey B. Sarnat -- Infections of the nervous system / Bernard L. Maria, James F. Bale, Jr., and G. Ellis Ziel -- Autoimmune and postinfectious diseases / Agustin Legido ... [et al.] -- Postnatal trauma and injuries by physical agents / John H. Menkes and Richard G. Ellenbogen -- Toxic and nutritional disorders / John H. Menkes -- Tumors of the nervous system / Bernard L. Maria and John H. Menkes -- Neurocutaneous syndromes / Bernard L. Maria and John H. Menkes -- Cerebrovascular disorders / Cesar C. Santos and E. Steve Roach -- Paroxysmal disorders / Raman Sankar ... [et al.] -- Headaches and nonepileptic episodic disorders / A. David Rothner and John H. Menkes -- Diseases of the motor unit / John H. Menkes and Harvey B. Sarnat -- Neurologic manifestations of systemic illness / S. Robert Snodgrass -- Disorders of mental development / Marcel Kinsbourne and Frank Wood.
  • During the past decade, significant advances have been made in the field of neurodevelopmental disorders, resulting in a considerable impact on conceptualization, diagnostics, and practice. The second edition of Child Neuropsychology: Assessment and Interventions for Neurodevelopmental Disorders brings readers up to speed clearly and authoritatively, offering the latest information on neuroimaging technologies, individual disorders, and effective treatment of children and adolescents. Starting with the basics of clinical child neuropsychology and functional anatomy, the authors present a transactional framework for assessment, diagnosis, and intervention. The book carefully links structure and function - and behavioral and biological science - for a more nuanced understanding of brain development and of pathologies as varied as pervasive developmental disorders, learning disabilities, neuromotor dysfunction, seizure disorders, and childhood cancers. This volume features a range of salient features valuable to students as well as novice and seasoned practitioners alike, including: overview chapters that discuss the effects of biogenic and environmental factors on neurological functioning; new emphasis on multicultural/cross-cultural aspects of neuropsychology and assessment; brand new chapters on interpretation, neuropsychological assessment process, and report writing; an integrative model of neurological, neuroradiological, and psychological assessment and diagnosis; balanced coverage of behavioral, pharmacological, and educational approaches to treatment; case studies illustrating typical and distinctive presentations and successful diagnosis, treatment planning, and intervention; and important practice updates, including the new HIPAA regulations. Child Neuropsychology, 2nd Edition, is vital reading for school, clinical child, and counseling psychologists as well as neuropsychologists.
  • 1. A Clinician's Approach to Chorea / Peter A. LeWitt -- 2. Benign Hereditary Chorea / Carlos Zúñiga-Ramírez and Héctor Alberto González-Usigli -- 3. Chorea-Acanthocytosis / Andreas Hermann -- 4. Sydenham's Chorea / Francisco Cardoso -- 5. Huntington's Disease: Clinical Phenotypes and Therapeutics / Michael Orth -- 6. Huntington's Disease: Molecular Pathogenesis and New Therapeutic Perspectives / Claudia Perandones and Ignacio Muñoz-Sanjuan -- 7. Huntington Disease and Huntington Disease-Like Syndromes: An Overview / Susanne A. Schneider and Felix Gövert -- 8. McLeod Syndrome / Hans H. Jung -- 9. Neuroferritinopathy / Vanderci Borges and Roberta Arb Saba -- 10. Neurodegeneration with Brain Iron Accumulation / Nardocci Nardo , Vanessa Cavallera , Luisa Chiapparini, and Giovanna Zorzi -- 11. Aceruloplasminemia / Hiroaki Miyajima -- 12. Chorea in Inherited Ataxias / Hélio A. Ghizoni Teive and Renato Puppi Munhoz -- 13. Chorea in Prion Diseases / Marie-Claire Porter and Simon Mead -- 14. Inherited Metabolic Disorders Causing Chorea / Mônica Santoro Haddad -- 15. Drug-Induced Chorea / Federico E. Micheli -- 16. Structural Causes of Chorea / Jon Snider and Roger L. Albin -- 17. Chorea: A Surgical Approach / Raul Martinez-Fernandez and Elena Moro -- 18. Chorea in Childhood / Emilio Fernández-Alvarez -- 19. Psychogenic Chorea / Juan Carlos Giugni , Daniel Martínez-Ramírez, and Ramon L. Rodríguez-Cruz.
  • It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. Philosophical and social concepts of pain; testimonials of chronic-pain patients. Clinical data from pain patients' brains. Advances in noninvasive brain imaging for pain patients. Combining theoretical and empirical approaches to the analysis of pain-related brain function. Manipulation of brain function in animal models. Emerging neurotechnology principles for pain diagnostics and therapeutics.
  • Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more recently, Wnt signaling pathways upon cilia to regulate fate decisions and morphogenesis. Both primary and motile cilia also play crucial roles in the function of the nervous system, including the primary processing of sensory information, the control of body mass, and higher functions such as behavior and cognition, serving as 'antennae' for neurons to sense and process their environment. In this book we describe the structure and function of cilia and the various tissues throughout the brain and spinal cord that are dependent upon cilia for their proper development and function.
  • Surface anatomy of the back and vertebral levels of clinically important structures / Barclay W. Bakkum -- General characteristics of the spine / Gregory D. Cramer -- General anatomy of the spinal cord / Susan A. Darby -- Muscles that influence the spine / Barclay W. Bakkum, Gregory D. Cramer -- The cervical region / Gregory D. Cramer -- The thoracic region / Gregory D. Cramer -- The lumbar region / Gregory D. Cramer -- The sacrum, sacroiliac joint, and coccyx / Gregory D. Cramer, Chae-Song Ro -- Neuroanatomy of the spinal cord / Susan A. Darby, Robert J. Frysztak -- Neuroanatomy of the autonomic nervous system / Susan A. Darby -- Pain of spinal origin / Gregory D. Cramer, Susan A. Darby, Robert J. Frysztak -- Development of the spine and spinal cord / Barclay W. Bakkum, William E. Bachop -- Unique anatomic features of the pediatric spine / Gregory D. Cramer -- Microscopic anatomy of the zygapophysial joints, intervertebral discs, and other major tissues of the back / Gregory D. Cramer, Barclay W. Bakkum.
  • Clinical Application of Neuromuscular Techniques, Volume 2 - The Lower Body discusses the theory and practice of the manual treatment of chronic pain, especially with regards to the soft tissues of the lower body.
  • This book presents the concepts underlying the measurement of parasympathetic and sympathetic (P & S) activity in the autonomic nervous system and the application of these measurements in the development of therapeutic guidelines for treating dysfunctions in these processes. It provides an overview of the anatomy, physiology, and biochemistry of the autonomic nervous system; details general clinical applications of P & S monitoring that are independent of specialty or disease; presents the pathophysiology of P & S dysfunction in specific disorders, expected test results, therapeutic options, and expected outcomes; and includes case studies and longitudinal studies that demonstrate the major concepts for the common diseases for which P & S monitoring is recommended. Clinical Autonomic Dysfunction enables clinicians to improve patient outcomes by identifying and treating clinical problems related to autonomic nervous system disorders.
  • The second, revised edition of this successful textbook provides an up-to-date description of the use of preoperative functional magnetic resonance imaging (fMRI) in patients with brain tumors and epilepsies. State of the art fMRI procedures are presented, with detailed consideration of practical aspects, imaging and data processing, normal and pathological findings, and diagnostic possibilities and limitations. Relevant information on brain physiology, functional neuroanatomy, imaging technique, and methodology is provided by recognized experts in these fields. Compared with the first edition, chapters have been updated to reflect the latest developments and in particular the current use of diffusion tensor imaging (DTI) and resting-state fMRI. Entirely new chapters are included on resting-state presurgical fMRI and the role of DTI and tractography in brain tumor surgery. Further chapters address multimodality functional neuroimaging, brain plasticity, and pitfalls, tips, and tricks. The book is designed to be of value to beginners, trained clinicians, and experts alike.
  • General aspects of epilepsies -- Epileptic seizures and their classification -- Status epilepticus -- Imitators of epileptic seizures -- Epileptic syndromes and their classification -- EEG and brain imaging -- Principles of therapy in the epilepsies -- Neonatal epileptic seizures and neonatal epileptic syndromes -- Idiopathic epileptic seizures and syndromes in infancy -- Epileptic encephalopathies in infancy and early childhood -- Severe neocortical epileptic syndromes in infancy and childhood -- Benign childhood focal seizures and related epileptic syndromes -- Idiopathic generalised epilepsies -- Familial (autosomal dominant) focal epilepsies -- Symptomatic and cryptogenic (probably symptomatic) focal epilepsies -- Reflex seizures and related epileptic syndromes -- Diseases frequently associated with epileptic seizures -- Pharmacopoeia.
  • Part I. Overview -- Defining insomnia / H.P. Attarian and M.L. Perlis -- Epidemiology of insomnia / Ritu Grewal and Karl Doghramji -- Physiological basis of insomnia / Michael H. Bonnet and Donna L. Arand -- Differential diagnosis of insomnia / Michael Saletu and Bernd Saletu -- Insomnia in primary care practice with a special focus for the midlevel practitioner / Nancy I. Resi -- Part II. Insomnia in special populations -- Behavioral insomnias of childhood: assessment and treatment / Daniel S. Lewin and Edward Huntley -- Insomnia in teens / John Garcia -- Insomnia during pregnancy / Beth Ann Ward -- Menopausal insomnia / Tarja Saaresranta, Päivi Polo-Kantola, and Olli Polo -- Sleep and aging: insomnia in the geriatric population / Clifford Singer and Francine Nanda -- Part III. The primary insomnias -- Psychophysiological insomnia / Mary B. O'Malley and Edward B. O'Malley -- Idiopathic insomnia / Garrick Applebee -- Paradoxical insomnia / Hrayr Attarian -- Sleep hygiene / Hrayr Attarian -- Part IV. The secondary insomnias -- Insomnia caused by medical disorders / Kenneth Plotkin -- Insomnia in neurological diseases and disorders / Federica Provini, Carolina Lombardi, and Elio Lugaresi -- Insomnia in psychiatric disorders / Samy S. Karaz -- Circadian rhythms and insomnia / Leon C. Lack and Helen R. Wright -- Insomnia secondary to sleep-related breathing disorders / Brooke G. Judd -- Insomnia as a presenting symptom of sleep-related movement disorders, hypersomnias and parasomnias / Keith J. Nagle -- Insomnia and pain disorders / Catherine C. Schuman and Melissa M. Clark -- Part V. Treatments -- Cognitive-behavioral therapy for insomnia / M.L. Perlis, M.T. Smith, C. Jungquist, S. Nowakowski, H. Orff, and J. Soeffing -- Pharmacological treatment of insomnia / Paula K. Schweitzer, Denise Troy Curry, Rhody D. Eisenstein, and James K. Walsh -- Part VI. Appendix. Contents/directory.
  • Clinical neuroanatomy 2013 (27th ed.).
    AccessMedicine
  • Clinical Neuroanatomy and Neuroscience by Drs. M.J.T. FitzGerald, Gregory Gruener, and Estomih Mtui, already known as the most richly illustrated book available to help you through the complexity of neuroscience, brings you improved online resources with this updated edition. You'll find the additional content on Student Consult includes one detailed tutorial for each chapter, 200 USMLE Step I questions, and MRI 3-plane sequences. With clear visual images and concise discussions accompanying the text's 30 case studies, this reference does an impressive job of integrating clinical neuroanatomy with the clinical application of neuroscience. Aid your comprehension of this challenging subject by viewing more than 400 explanatory illustrations drawn by the same meticulous artists who illustrated Gray's Anatomy for Students. Get a complete picture of different disorders such as Alzheimer's disease and brain tumors by reading about the structure, function, and malfunction of each component of the nervous system. Grasp new concepts effortlessly with this book's superb organization that arranges chapters by anatomical area and uses Opening Summaries, Study Guidelines, Core Information Boxes, Clinical Panels, and 23 "flow diagrams," to simplify the integration of information. Use this unique learning tool to help you through your classes and prep for your exams, and know that these kind of encompassing tutorials are not usually available for self-study.
  • "Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death may progress through connections. Knowledge of how the various parts of the brain are interconnected to form functional systems is a prerequisite for the proper understanding of data from all fields in the neurosciences. Clinical Neuroanatomy: Brain Circuitry and Its Disorders bridges the gap between neuroanatomy and clinical neurology. It emphasizes human and primate data in the context of disorders of brain circuitry which are so common in neurological practice. In addition, numerous clinical cases demonstrate how normal brain circuitry may be interrupted and to what effect. Following an introduction into the organization and vascularisation of the human brain and the techniques to study brain circuitry, the main neurofunctional systems are discussed, including the somatosensory, auditory, visual, motor, antonomic and limbic systems, the cerebral cortex and complex cerebral functions."--Publisher's website.
  • This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischemic causes. The introductory chapters give an overview of the development of the human brain and the spinal cord, the mechanisms of development as obtained in experimental studies of various invertebrates and vertebrates, and the causes of congenital malformations. In the main part, the developmental disorders of the human brain and the spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These are underlined by carefully chosen clinical case studies, including imaging data and, when available, postmortem verification of the developmental disorders involved. Numerous color photographs and illustrations complement the text. This second edition emphasizes the prenatal diagnosis by ultrasound, MRI, and DTI and implements new classifications of developmental disorders.
  • Clinical neuroendocrinology 2014
    ScienceDirect
    Ch. 1. Genetic aspects of hypothalamic and pituitary gland development -- Ch. 2. Neuroendocrinology of pregnancy and parturition -- Ch. 3. Disorders of water metabolism: diabetes insipidus and the syndrome of inappropriate antidiuretic hormone secretion -- Ch. 4. The role of oxytocin and vasopressin in emotional and social behaviors -- Ch. 5. Corticotropin-releasing hormone and the hypothalamic-pituitary-adrenal axis in psychiatric disease -- Ch. 6. Genetic aspects of human obesity -- Ch. 7. Sleep characteristics and insulin sensitivity in humans -- Ch. 8. Hypothalamic-pituitary hormones during critical illness: a dynamic neuroendocrine response -- Ch. 9. Central regulation of the hypothalamo-pituitary-thyroid (HPT) axis: focus on clinical aspects -- Ch. 10. Evaluation of pituitary function -- Ch. 11. Imaging of pituitary pathology -- Ch. 12. Nonfunctioning pituitary tumors -- Ch. 13. Hyperprolactinemia and prolactinoma -- Ch. 14. Acromegaly -- Ch. 15. Cushing's disease -- Ch. 16. Craniopharyngioma -- Ch. 17. Rathke's cleft cyst -- Ch. 18. Alternative causes of hypopituitarism: traumatic brain injury, cranial irradiation and infections -- Ch. 19. Surgical approach to pituitary tumors -- Ch. 20. Medical approach to pituitary tumors -- Ch. 21. Radiation therapy in the management of pituitary adenomas -- Ch. 22. Nelson syndrome: definition and management -- Ch. 23. Familial pituitary tumors -- Ch. 24. Long-term effects of treatment of pituitary adenomas -- Ch. 25. Neuroendocrine mechanisms in athletes -- Ch. 26. Uncertainties in endocrine substitution therapy for central hypocortisolism -- Ch. 27. Uncertainties in endocrine substitution therapy for central endocrine insufficiencies: hypothyroidism -- Ch. 28. Uncertainties in endocrine substitution therapy for central endocrine insufficiencies: growth hormone deficiency -- Ch. 29. Autoimmune hypophysitis: new developments -- Index.
  • MS: Pathology and Immunology -- MS: Epidemiology and Genetics -- MS: Clinical Features, Symptom Management, and Diagnosis -- Advances in Magnetic Resonance Imaging of Multiple Sclerosis -- Disease Modifying Agents in the Treatment of Multiple Sclerosis -- Pediatric Multiple Sclerosis -- Is Multiple Sclerosis a Vascular Disease? -- Multiple Sclerosis: The Next 20 Years -- Introduction to Neuroimmunology -- Acute Disseminated Encephalomyelitis -- Neuromyelitis Optica Spectrum Disorders -- The Neuroimmunology of Cancer -- Infections of the Central Nervous System -- The Neuroimmunology of Cortical Disease (Dementia, Epilepsy, and Autoimmune Encephalopathies) -- Autoimmune Movement Disorders -- CNS Vasculitis -- Principles of Immunotherapy -- Immunologic Disorders of Neuromuscular Junction and Muscle -- Autoimmune Neuropathies -- Systemic Autoimmune Diseases with Neurological Manifestations.
  • Clinical neurology (Appleton & Lange) 2012 (8th ed.)
    AccessMedicine
  • Over the past two decades, electrophysiology has undergone unprecedented changes thanks to technical improvements, which simplify measurement and analysis and allow more compact data storage. This book covers in detail the spectrum of electrophysiology applications in patients with disorders of consciousness. Its content spans from clinical aspects of the management of subjects in the intensive care unit, including EEG, evoked potentials and related implications in terms of prognosis and patient management to research applications in subjects with ongoing consciousness impairment. While the first section provides up-to-date information for the interested clinician, the second part highlights the latest developments in this exciting field. The book comprehensively combines clinical and research information related to neurophysiology in disorder-of- consciousness patients, making it an easily accessible reference for neuro-ICU specialists, epileptologists and clinical neurophysiologists as well as researchers utilizing EEG and event-related potentials. ℗ℓ
  • Neurotherapy, sometimes called EEG biofeedback and/or neurobiofeedback involves techniques designed to manipulate brain waves through non-invasive means and are used as treatment for a variety of psychological and medical disorders. The disorders covered include ADHD, mood regulation, addiction, pain, sleep disorders, and traumatic brain injury. This book introduces specific techniques, related equipment and necessary training for the clinical practitioner. Sections focus on treatment for specific disorders and which individual techniques can be used to treat the same disorder and examples.
  • Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You'll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors, such as heavy metals and pesticides, and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. And, Expert Consult functionality allows you to access the full text of the book online, from any Internet connection.
  • This text prepares its users to deliver expert care in this most challenging nursing specialty. It addresses neuroanatomy, assessment, diagnostic evaluation and management of the complete range of neurological disorders for which nurses provide patient care, including trauma, stoke, tumors, seizures, headache, aneurysms, infections, degenerative disorders and features new chapters on neurological critical care and peripheral neuropathies. The new edition has been thoroughly revised to reflect standards of care based on evidence-based practice. It now includes separate pathophysiology sections in each chapter, new resource guides, such as internet sites and professional and patient information sources, key points summaries, evidence-based boxes, and nursing research features.
  • Mechanisms of functional recovery after stroke / Ko, S.-B.; Yoon, B.-W -- Diagnostic approach to functional recovery : functional magnetic resonance imaging in stroke / Havsteen, I. ... [et al.] -- Diagnostic approach to functional recovery : diffusion-weighted imaging and tractography / Raffin, E.; Dyrby, T -- Compensatory development of the contralateral pyramidal tract after experimental cerebral ischemia / Takatsuru, Y.; Nakamura, K.; Nabekura, J -- Compensatory contribution of the contralateral pyramidal tract after stroke / Otsuka, N. ... [et al.] -- Regeneration of neuronal cells following cerebral injury / Dailey, T. ... [et al.] -- Translational challenge for cell therapy following stroke / Kuroda, S.; Houkin, K. -- Experimental and clinical challenge for neuroregeneration following stroke / Kasahara, Y.; Ihara, M.; Taguchi, M. -- Therapeutic drug approach to stimulate clinical recovery after brain injury / Krieger, D.W. -- Rehabilitation and plasticity / Luft, A.R. -- A brain-computer interface to support functional recovery / Kjaer, T.W.; Sorensen, H.B. -- Novel methods to study aphasia recovery after stroke / Hartwigsen, G.; Siebner, H.R. -- Role of repetitive transcranial magnetic stimulation in stroke rehabilitation / Pinter, M.M.; Brainin, M. -- Influence of therapeutic hypothermia on regeneration after cerebral ischemia / Yenari, M.A.; Han, H.S. -- Reasonable suppression of body weight with high-voltage electric potential therapy in humans: a translational study to increase brain-derived neurotrophic factor levels in the brain / Hiroji, Y. ... [et al.] -- Prevention of post-stroke disuse muscle atrophy with a free radical scavenger / Naritomi, H.
  • The impaired brain has often been difficult to rehabilitate owing to limited knowledge of the brain system. Recently, advanced imaging techniques such as fMRI and MEG have allowed researchers to investigate spatiotemporal dynamics in the living human brain. Consequently, knowledge in systems neuroscience is now rapidly growing. Advanced techniques have found practical application by providing new prosthetics, such as brain?machine interfaces, expanding the range of activities of persons with disabilities, or the elderly. The book?s chapters are authored by researchers from various research fields such as systems neuroscience, rehabilitation, neurology, psychology, and engineering. The book explores the latest advancements in neurorehabilitation, plasticity, and brain?machine interfaces among others, and constitutes a solid foundation for researchers who aim to contribute to the science of brain function disabilities and ultimately to the well-being of patients and the elderly worldwide.
  • Carbamazepine -- Felbamate -- Gabapentin -- Lamotrigine -- Levetiracetam -- Oxcarbazepine -- Phenobarbital, primidone -- Phenytoin -- Pregabalin -- Tiagabine -- Topiramate -- Valproic -- Zonisamide.
  • Covers three areas of research in brain tumors: a) animal models for brain tumors, including spontaneous occurrence of brain tumors in mammals, transgenic models in rodents and transplant models; b) Prognostic factors and biomarkers; c) Therapeutic targets and targeting approaches to brain tumors.
  • "This clinically oriented book covers selected infections of the central nervous system which are of considerable current interest. Aspects that are less well documented, such as spinal cord infections, central nervous system infections in patients with cancer, tropical infections, healthcare-associated ventriculitis or meningitis, and immunological problems in the international traveler are also discussed, as these are all problems relevant to daily practice."--Publisher's website.
  • This new graduate level textbook, Cognition and Acquired Language Disorders: An Information Processing Approach, addresses the cognitive aspects of language and communication. It assembles the most recent information on this topic, addressing normal cognitive processing for language in adults, the cognitive impairments underlying language disorders arising from a variety of neurologic conditions, and current assessment and treatment strategies for the management of these disorders. The text is organized using an information processing approach to acquired language disorders, and thus can be set apart from texts that rely upon a more traditional, syndrome-based approach (e.g., stroke, dementia, and traumatic brain injury). This approach facilitates the description and treatment of acquired language disorders across many neurologic groups when particular cognitive deficits are identified. Other useful features of the text include assessment and treatment protocols that are based on current evidence. These protocols provide students and clinicians a ready clinical resource for managing language disorders due to deficits in attention, memory, linguistic operations, and executive functions. Unique process-oriented approach organizes content by cognitive processes instead of by syndromes so you can apply the information and treatment approaches to any one of many neurologic groups with the same cognitive deficit. Cognitive domains are described as they relate to communication rather than separated as they are in many other publications where they are treated as independent behaviors. A separate section on normal processing includes five chapters providing a strong foundation for understanding the factors that contribute to disordered communication and its management. The evidence-based approach promotes best practices for the most effective management of patients with cognitive-communication disorders. Coverage of the cognitive aspects of communication helps you meet the standards for certification in speech-language pathology. A strong author team includes two lead authors who are well known and highly respected in the academic community, along with expert contributors, ensuring a comprehensive, advanced clinical text/reference.
  • Medical and Psychosocial Aspects of Cognitive Enhancement -- Pharmacological Neuroenhancement: Substances and Epidemiology / Andreas G. Franke, Klaus Lieb -- Psychopharmacological Neuroenhancement: Evidence on Safety and Efficacy / Dimitris Repantis -- A Bubble of Enthusiasm: How Prevalent Is the Use of Prescription Stimulants for Cognitive Enhancement? / Bradley Partridge -- Modeling the Effects of Modafinil on Selective Attention Electroencephalographic Neural Correlates / Carlos Trenado -- Behavioral Neuroenhancement / Martin Dresler -- The Influence of Sports on Cognitive Task Performance - A Critical Overview / Pavel Dietz -- The Human Experiment: How We Won't Win the Rat Race. What Can We Learn from Brain Stimulation in Humans and Rats About Enhancing the Functional Neurobiology of Higher Cognitive Functions? / Colleen A. Dockery -- Philosophical and Ethical Aspects of Cognitive Enhancement -- Better Brains or Bitter Brains? The Ethics of Neuroenhancement / Kirsten Brukamp -- Cognitive Enhancement - To What End? / Michael Hauskeller -- Nano-bionic Devices for the Purpose of Cognitive Enhancement: Toward a Preliminary Ethical Framework / Frédéric Gilbert -- Cognitive-Enhancing Drugs, Behavioral Training and the Mechanism of Cognitive Enhancement / Emma Peng Chien -- What Is Cognitive Enhancement and Is It Justified to Point Out This Kind of Enhancement Within the Ethical Discussion? / Roland Kipke -- No Pain, No Gain? Objections to the Use of Cognitive Enhancement on the Basis of Its Potential Effects on the Value of Achievement / Lisa Forsberg -- Does the Cognitive Enhancement Debate Call for a Renewal of the Deliberative Role of Bioethics? / Cynthia Forlini, Eric Racine -- Sociological, Political and Legal Aspects of Cognitive Enhancement -- The Biopolitics of Cognitive Enhancement / Peter B. Reiner -- Are We Heading Towards an 'Enhancement Society'? / Armin Grunwald -- Leveling the Playing Field: Fairness in the Cognitive Enhancement Debate / Greta Wagner -- My Mind Is Mine!? Cognitive Liberty as a Legal Concept / Jan-Christoph Bublitz -- Cognitive Enhancement and Criminal Behavior / Elizabeth Shaw -- Enhanced Control and Criminal Responsibility / John Danaher.
  • 1. History of Cognitive Rehabilitation -- 2. The Role of Assessment in Treatment Planning -- 3. Treatment Strategies -- 4. Cognitive Remediation with NeurXercise -- 5. Treatment Generalization and Ecological Validity -- 6. A NeurXercise Casebook -- 7. Conclusions -- Appendicies A-N.
  • Self-organization in the nervous system / David Willshaw -- Large-scale, small-scale systems / Jim Austin ... [et al.] -- Representation / Vincent Walsh and Simon Laughlin -- Sensory processing / Lionel Tarassenko and Mike Denham -- Speech and language / William D. Marslen-Wilson -- Action / Philip Barnard and Peter Redgrave -- Social cognition / Uta Frith and Sarah-Jayne Blakemore -- Motivation, planning and interaction / Nicholas R. Jennings and Anthony G. Cohn ... [et al.] -- Learning and memory / Richard Morris ... [et al.] -- Memory, reasoning and learning / Kieron O'Hara ... [et al.] -- Advanced neuroscience technologies / Bashir Ahmed ... [et al.] -- Applications and impact / Bill Sharpe.
  • Describes the COMPASS model for working with preschool and elementary age students with autism spectrum disorders. This book offers a framework for individualized assessment and program planning based in students' life experiences along with family and teacher input. At the same time, its two-tiered consultation/coaching strategy is designed to minimize the setbacks that occur even in optimal family and classroom situations. Featured in the text: theory and rationale behind COMPASS; self-evaluation tools for assessing core skills and competencies; guidelines for writing effective Individual Education Programs and the COMPASS Action Plan; detailed instructions for implementing Action Plans and monitoring progress; case studies of the COMPASS program in real-life situations; a complete kit of forms, scales, and checklists.
  • One of the challenges the field of clinical neuropsychology faces is to develop an assessment process that is relevant and responsive to the needs of patients. This book describes developments in methods of neuropsychological assessment feedback that involve patients in an open exchange of information and results.
  • Basic elements of the nervous system -- Spinal cord and spinal nerves -- Brain stem and cranial nerves -- Cerebellum -- Diencephalon -- Telencephalon -- Cerebrovascular and ventricular sytstems -- Autonomic nervous system -- Functional systems -- The eye -- The ear.
  • Behavioral Assessment and Diagnosis of Disorders of Consciousness / Caroline Schnakers and Steve Majerus -- Prognosis of Patients with Altered State of Consciousness / Marie-Aurélie Bruno, Didier Ledoux, Audrey Vanhaudenhuyse, Olivia Gosseries and Aurore Thibaut, et al. -- Functional Imaging and Impaired Consciousness / Audrey Vanhaudenhuyse, Melanie Boly, Marie-Aurélie Bruno, Olivia Gosseries and Athena Demertzi, et al. -- Multivariate Pattern Recognition Analysis: Brain Decoding / Jessica Schrouff and Christophe L. M. Phillips -- Spectroscopy and Diffusion Tensor Imaging in Disorders of Consciousness / Jean-Flory Luaba Tshibanda, Athena Demertzi and Andrea Soddu -- Electrophysiology and Disorders of Consciousness / Quentin Noirhomme and Rémy Lehembre -- Brain-Computer Interface: A Communication Aid? / Camille Chatelle, Zulay Lugo, Quentin Noirhomme, Bettina Sorger and Dorothee Lulé -- Using Transcranial Magnetic Stimulation to Measure Cerebral Connectivity in Patients with Disorders of Consciousness / Melanie Boly, Olivia Gosseries, Marie-Aurélie Bruno, Mario Rosanova and Marcello Massimini -- Sleep in Disorders of Consciousness / Victor Cologan and Manuel Schabus -- Sensory Stimulation Program / Haibo Di and Caroline Schnakers -- Feasibility of Oral Feeding in Patients with Disorders of Consciousness / Audrey Maudoux, Ingrid Breuskin, Olivia Gosseries, Caroline Schnakers and Audrey Vanhaudenhuyse -- Pharmacological Treatments / Olivia Gosseries, Marie Thonnard and Steven Laureys -- Deep Brain Stimulation / Marie Thonnard -- The Ethics of Managing Disorders of Consciousness / Athena Demertzi, Olivia Gosseries, Marie-Aurélie Bruno, Caroline Schnakers and Audrey Vanhaudenhuyse, et al. -- Future Perspectives of Clinical Coma Science / Steven Laureys and Caroline Schnakers.
  • What is dementia? -- Signposts : what to look for and when to seek help -- Finding help -- Preparing for a visit to the doctor -- Making the most of the doctor's visit -- The seven common senses of dementia care -- Caring for the caregiver -- Dementia medications -- Alternative therapies in dementia -- Alcohol and other substances -- Mood issues in dementia -- Psychosis -- Dealing with problem behaviors in dementia -- Legal and financial matters -- Selecting level of care -- Looking ahead : the later stages.
  • Neuroanatomy / Jose Rafols, Gregory P. Van Stavern, and Marchello Cherchi -- Vascular diseases of the nervous system / Mark K. Borsody, Renee Bailey Van Stavern -- Seizures and epilepsy / Stephan Schuele -- Disorders of myelination / Rana Zabad -- Tumors of the nervous system / Jeffrey Raizer -- Headache and pain disorders / Jan Lewis Brandes and Susan Roberson -- Behavioral neurology and psychiatry / Randall Benson ... [et al.] -- Movement disorders / Aleksander Videnovic -- Diseases of the nerves / Jeffrey Allen -- Diseases of the muscles / Huned Patwa and Hajime Tokuno -- Infections of the nervous system / Mahmoud Rayes and Alexandros Tselis -- Development and metabolic diseases of the nervous system / Alexander Bassuk -- Systemic diseases affecting the nervous system / Casey Dunn, Jeff Wiese, and Joe Tarsia.
  • This volume, 'Computational Models of the Auditory System', will have as its unifying theme a systems approach where the focus will be on studies whose intent is to contribute to the big picture of hearing.
  • Pt. 1. Pharmacological-based models of addiction -- pt. 2. Neurocomputational models of addiction -- pt. 3. Economic-based models of addiction.
  • Functional Genomics and Molecular Networks Gene Expression Regulations in Complex Diseases: Down Syndrome as a Case Study / Marie-Claude Potier and Isabelle Rivals -- Reconstructing Models from Proteomics Data / Lysimachos Zografos, Andrew J. Pocklington and J. Douglas Armstrong -- Using Chemical Kinetics to Model Neuronal Signalling Pathways / Lukas Endler, Melanie I. Stefan, Stuart J. Edelstein and Nicolas Le Novère -- Breakdown of Mass-Action Laws in Biochemical Computation / Fidel Santamaria, Gabriela Antunes and Erik De Schutter -- Spatial Organization and Diffusion in Neuronal Signaling / Sherry-Ann Brown, Raquell M. Holmes and Leslie M. Loew -- The Performance (and Limits) of Simple Neuron Models: Generalizations of the Leaky Integrate-and-Fire Model / Richard Naud and Wulfram Gerstner -- Multi-compartmental Models of Neurons / Upinder S. Bhalla -- Noise in Neurons and Other Constraints / A. Aldo Faisal -- Methodological Issues in Modelling at Multiple Levels of Description / Kevin Gurney and Mark Humphries -- Virtues, Pitfalls, and Methodology of Neuronal Network Modeling and Simulations on Supercomputers / Anders Lansner and Markus Diesmann -- Co-operative Populations of Neurons: Mean Field Models of Mesoscopic Brain Activity / David T. J. Liley, Brett L. Foster and Ingo Bojak -- Cellular Spacing: Analysis and Modelling of Retinal Mosaics / Stephen J. Eglen -- Measuring and Modeling Morphology: How Dendrites Take Shape / Todd A. Gillette and Giorgio A. Ascoli -- Axonal Growth and Targeting / Duncan Mortimer, Hugh D. Simpson and Geoffrey J. Goodhill -- Encoding Neuronal Models in SBML / Sarah M. Keating and Nicolas Le Novère -- NeuroML / Padraig Gleeson, Volker Steuber, R. Angus Silver and Sharon Crook -- XPPAUT / Bard Ermentrout -- NEST by Example: An Introduction to the Neural Simulation Tool NEST / Marc-Oliver Gewaltig, Abigail Morrison and Hans Ekkehard Plesser.
  • Neuronal dendritic trees are complex structures that endow the cell with powerful computing capabilities and allow for high neural interconnectivity. Studying the function of dendritic structures has a long tradition in theoretical neuroscience, starting with the pioneering work by Wilfrid Rall in the 1950s. Recent advances in experimental techniques allow us to study dendrites with a new perspective and in greater detail. The goal of this volume is to provide a rsum of the state-of-the-art in experimental, computational, and mathematical investigations into the functions of dendrites in a variety of neural systems. Thebook firstlooks at morphological properties of dendrites and summarizes the approaches to measure dendrite morphology quantitatively and to actually generate synthetic dendrite morphologies in computer models. This morphological characterization ranges from the study of fractal principles to describe dendrite topologies, to the consequences of optimization principles for dendrite shape. Individual approaches are collected to study the aspects of dendrite shape that relate directly to underlying circuit constraints and computation. The second main theme focuses on how dendrites contribute to the computations that neurons perform. What role do dendritic morphology andthe distributions of synapses and membrane properties over the dendritic tree have in determining the output of a neuron in response to its input? A wide range of studies is brought together, with topics ranging from general to system-specific phenomenasome having a strong experimental component, and others being fully theoretical. The studies come from many different neural systems and animal species ranging from invertebrates to mammals. With this broad focus, an overview is given of the diversity of mechanisms that dendrites can employ to shape neural computations.
  • Concussion 2014
    Karger
    Cerebral concussion : a historical perspective / Maroon, J.C -- Biomechanics of concussion / B.D. Stemper, F.A. Pintar -- The neurophysiology of concussion / D.A. Hovda -- Chronic traumatic encephalopathy / B. Omalu -- Cumulative effects of repetitive mild traumatic brain injury / J.E. Bailes, M.L. Dashnaw, A.L. Petraglia, R.C. Turner -- Understanding concussive injuries using investigational imaging methods / L.C. Henry -- Neurometabolic, electrophysiological, and imaging abnormalities / E. Chamard, M. Lassonde, H. Théoret -- Detection of white matter injury in concussion using high-definition fiber tractography / S.S. Shin, S. Pathak, N. Presson, W. Bird, L. Wagener, W. Schneider, D.O. Okonkwo, J.C. Fernandez-Miranda -- Magnetoencephalography in the diagnosis of concussion / R.R. Lee, M. Huang -- Evidence-based management of sport-related concussion / M. McCrea, K. Guskiewicz -- In-office management of sport-related concussion / E. Reynolds, M.W. Collins -- Treating prolonged symptoms of mild traumatic brain injury : neuropharmacology / K. Lercher, C. Camiolo Reddy -- Rehabilitation from postconcussion syndrome : nonpharmacological treatment / A.L. Nelson Sheese, T.A. Hammeke -- Concussion in ice hockey / C.M. Bonfield, D.A. Wecht, L.D. Lunsford -- Management of concussion in the professional football player / E.M. Pieroth, C. Hanks -- Developing an interdisciplinary community-based sports concussion management program / A. LoGalbo, C.M. Salinas, M. Dougherty, M. Field -- The multidisciplinary concussion management program / D.M. Panczykowski, J.E. Pardini -- Vulnerability in speed of visuomotor ability / A.B. Shuttleworth-Edwards, S.E. Radloff, V.J. Whitefield-Alexander -- Detecting eye movement abnormalities from concussion / J. Maruta, J. Ghajar -- Neurodegenerative changes after mild traumatic brain injury / S. Fakhran, L. Alhilali -- Future directions in brain injury research / T.A. Gennarelli.
  • Consequences of Ignorance and Arrogance for Mismanagement of Sports-Related Concussions: Short- and Long-Term Complications -- Neuropsychological Testing in Sports Concussion Management: An Evidence-Based Model when Baseline Is Unavailable -- Feasibility of Virtual Reality for Assessment of Neurocognitive, Executive, and Motor Functions in Concussion -- Feasibility of Electroencephalography for Direct Assessment of Concussion -- The Relevance of Assessing Cerebral Metabolic Recovery for a Safe Return to Play Following Concussion -- The Biomechanics of Concussion: 60 Years of Experimental Research -- Acute and Lingering Impairments in Post-concussion Postural Control -- Biomechanical Studies of Impact and Helmet Protection -- Neuropathology of Mild Traumatic Brain Injury: Relationship to Structural Neuroimaging Findings -- Metabolic Dysfunction Following Traumatic Brain Injury -- Advanced Neuroimaging of Mild Traumatic Brain Injury -- Biomarkers for Concussion -- Functional Magnetic Resonance Imaging in Mild Traumatic Brain Injury -- Predicting Postconcussive Symptoms After Mild Traumatic Brain Injury in Children and Adolescents -- Long-Term Effects of Pediatric Mild Traumatic Brain Injury -- Neuropsychological Assessment of Sports-Related Concussion: Pediatric Challenges -- Management of Collegiate Sport-Related Concussions -- Sports-Related Subconcussive Head Trauma -- The Role of the Quantitative EEG in the Diagnosis and Rehabilitation of the Traumatic Brain Injured Patients -- Current Understanding of Concussion: Treatment Perspectives -- Post-concussion Syndrome, Persistent Symptomatic Concussion, Related Sequelae, and Treatment of Mild Closed Head Injury.
  • "Continuing the tradition of the bestselling first edition, this second edition provides comprehensive coverage of neurobehavioral disorders in children and adults following impact and acceleration accidents. Completely revised and updated, the book includes comprehensive coverage of consciousness including normal, acute, and persistent alterations. Drawing on his training, education, and experience in human physiology, neuroanatomy, and endocrinology, the author not only gives readers a solid foundation for understanding, diagnosing, and treating concussive brain trauma, but also gives them tools to increase standards of care"--Provided by publisher.
  • "Controversies in Stereotactic Radiosurgery: Best Evidence Recommendations is a comprehensive reference that compiles, synthesizes, and summarizes the most relevant scientific literature on the topic. Each succinct, problem-oriented chapter addresses a different controversy surrounding stereotactic radiosurgery. This book saves physicians significant amounts of time by distilling years of scientific research into sound guidelines that will help them make fully-informed treatment decisions. Key Features: Covers both intracranial and spine radiosurgery, providing complete coverage of this rapidly evolving technology Includes more than 35 chapters on treatment controversies for brain and spine tumors as well as vascular malformations Contains summary tables throughout the text that present the main conclusions of published studies All neurosurgeons, radiation oncologists, and neuro-oncologists, involved in the treatment of patients who may be candidates for stereotactic radiosurgery of the brain and spine will find this book to be an essential decision making guide".
  • Correlations of cellular activities in the nervous system : Physiological and methodological considerations -- Synchronization between sources : Emerging methods for understanding large-scale functional networks in the human brain -- Approaches to the detection of direct directed interactions in neuronal networks -- The phase oscillator approximation in neuroscience : An analytical framework to study coherent activity in neural networks -- From synchronisation to networks : Assessment of functional connectivity in the brain -- The size of neuronal assemblies, their frequency of synchronization, and their cognitive function -- Synchrony in neural networks underlying seizure generation in human partial epilepsies -- Detection of phase synchronization in multivariate single brain signals by a clustering approach -- Denoising and averaging techniques for electrophysiological data -- Dissection of synchronous population discharges in vitro -- Time-frequency methods and brain rhythm signal processing -- Complex network modeling : A new approach to neurosciences.
  • The study and modulation of cortical connections is a rapidly growing area in neuroscience. This unique book by prominent researchers in the field covers recent advances in this area. The first section of the book describes studies of cortical connections, modulation of cortical connectivity and changes in cortical connections with activities such as motor learning and grasping in primates. The second section covers the use of non-invasive brain stimulation to study and modulate cortical connectivity in humans. The last section describes changes in brain connectivity in neurological and psychiatric diseases, and potential new treatments that manipulate brain connectivity. This book provides an up-to-date view of the study of cortical connectivity, and covers its role in both fundamental neuroscience and potential clinical applications.
  • Schizophrenia genes: searching for common features, functions, and mechanisms -- Towards a molecular classification of illness: effects of schizophrenia susceptibility loci on clinical symptoms and cognitive function -- Homer: a genetic factor in schizophrenia? -- Neuroregulin-erbB signaling and the pathogenesis of schizophrenia -- Nicotinic cholinergic cortical dysfunction in schizophrenia -- Role for glutamate receptors, transporters, and interacting proteins in cortical dysfunction in schizophrenia -- Cortical circuit dysfunction in the NMDA receptor hypofunction model for the psychosis of schizophrenia -- Alterations in hippocampal function in schizophrenia: its genetic associations and systems implications -- Identifying novel target genes in psychotic disorder network association analyses -- Alterations in cortical GABA neurotransmission in schizophrenia: causes and consequences -- Increased cortical excitability as a critical element in schizophrenia pathophysiology.
  • This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.
  • This beautifully illustrated book combines a detailed exposition of the anatomy and function of the cranial nerves with practical coverage of clinical concepts for the assessment and differential diagnosis of cranial nerve dysfunction. An introductory chapter provides a brief overview of cranial nerve anatomy and function, skull base anatomy, classification of pathologies, and imaging approaches. Each of the twelve chapters that follow is devoted to in-depth coverage of a different cranial nerve. These chapters open with detailed discussion of the various functions of each nerve and normal anatomy. The authors then describe common lesions and present a series of cases that are complemented by CT images and MRIs to illustrate disease entities that result in cranial nerve dysfunction.
  • Development of the cerebellum -- Structural cerebellar plasticity -- Cell physiological cerebellar plasticity -- Imaging of cerebellar activity -- Oscillations and synchrony in cerebellar cortex and inferior olive -- Cerebellar motor control -- Cerebellar neuro-anatomical organization -- Excitability in cerebellar cortex -- Cerebellar pathology -- Epilogue.
  • Critical care in spinal cord injury / Michael G. Fehlings -- Epidemiology of traumatic and nontraumatic spinal cord injury / Vanessa K. Noonan, Marcel F. Dvorak & Michael G. Fehlings -- Novel insights into pathophysiology and emerging therapeutic opportunities / Nicole Forgione & Michael G. Fehlings -- Imaging evaluation of the injured spinal column and spinal cord / David W. Cadotte, David Mikulis & Michael G. Fehlings -- Acute spinal cord injury : clinical evaluation, diagnosis and classification / W. Bradley Jacobs & Rita Nguyen -- Nonoperative management of acute spinal cord injury / Steven Kirshblum, Monifa Brooks, Jeremiah Nieves & Peter Yonclas -- Surgery for acute spinal cord injury / Ravichandra A. Madineni, Angud Mehdi & James S. Harrop -- Principles of spinal cord rehabilitation / Michelle L. Starkey, Markus Wirz, Thomas M. Kessler & Armin Curt -- Prognosis for spinal cord injury / Fin Biering-Sørensen & Ralph Marino -- Emerging therapies for traumatic spinal cord injury / Newton Cho & Anick Nater -- Index.
  • Cultural neuroscience combines brain imaging techniques such as functional magnetic resonance imaging and event-related brain potentials with methods of social and cultural psychology to investigate whether and how cultures influence the neural mechanisms of perception, attention, emotion, social cognition, and other human cognitive processes. The findings of cultural neuroscience studies improve our understanding of the relation between human brain function and sociocultural contexts and help to reframe the 'big question' of nature versus nurture.blications and an overview on his outstanding life.
  • Current clinical neurology v. 44-, 2005-13 ; 2013-
    Springer
  • Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a blueprint for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
  • ch. 1. Neuroanatomical Methods -- ch. 2. Imaging -- ch. 3. Cellular and Developmental Neuroscience -- ch. 4. Gene Cloning, Expression, and Mutagenesis -- ch. 5. Molecular Neuroscience -- ch. 6. Neurophysiology -- ch. 7. Neurochemistry/Neuropharmacology -- ch. 8. Behavioral Neuroscience -- ch. 9. Preclinical Models of Neurologic and Psychiatric Disorders -- ch. 10. Human Neuroscience -- Appendix 1. Molecular Biology Techniques -- Appendix 2. Stock Solutions, Equipment, and Laboratory Guidelines -- Appendix 3. Commonly Used Techniques -- Appendix 4. Animal Techniques -- Appendix 5. Databases -- Suppliers.
  • Current topics in neurotoxicity v. 1-, 2012-
    Springer
    Consists of volumes that cover the latest developments in neurotoxicity studies including neurodegeneration, neuroprotection, and neuroregeneration. The series has a translational focus and addresses the causes of neurotoxicity associated with diseases such as Alzheimers, Parkinsons Disease, autism, HIV associated dementia etc.
  • Epidemiology of Gliomas -- Glioma biology and molecular markers -- Surgery for Gliomas-- Radiation therapy of Glioblastoma -- Low-grade Glioma -- Treatment of anaplastic Glioma -- Current medical treatment of Glioblastoma -- Novel chemotherapeutic approaches in adult high-grade Gliomas -- Immunotherapy for malignant Gliomas -- Glioblastoma in the elderly -- Palliative and supprotive care for Glioma patients.
  • The Peripheral Nerve and Cutaneous Neural Tumors: Introduction, Definitions, and Classification -- Special Techniques for the Study of Cutaneous Neural Tumors -- Nonneoplastic and Hamartomatous Lesions of the Cutaneous Peripheral Nerve -- Benign Cutaneous Neoplasms with Peripheral Nerve Differentiation -- Malignant Cutaneous Neoplasms with Peripheral Nerve Differentiation -- Cutaneous Proliferations with Putative Neural Differentiation -- Cutaneous Neuroblastic and Ganglion Cell Proliferations -- Cutaneous Glial and Meningothelial Proliferations -- Appendix: Practical Approach to Neural Tumors? Flowcharts and Differential Diagnostic Table.
  • Neurocysticercosis (neural infection by larvae of Taenia solium) occurs when humans become intermediate hosts of the tapeworm Taenia solium after ingesting its eggs, usually directly from a Taenia carrier. Nowadays, the disease is the most common helminthic infection of the nervous system in humans, and a major cause of acquired epilepsy. It has long been endemic in developing countries of Latin America, sub-Saharan Africa, the Indian subcontinent, and Southeast Asia. Recently, however, mass migration from endemic to non-endemic areas and growth in overseas travel have resulted in an increase in the prevalence of cysticercosis in countries where it was formerly considered exotic. The introduction of modern neuroimaging and serologic techniques has improved the diagnosis of neurocysticercosis, and the development of potent cysticidal drugs has changed the prognosis of most affected patients. Nevertheless, much remains to be learned about this parasitic disease. This book provides a comprehensive and up-to-date review of the various aspects of cysticercosis of the nervous system that will be of interest to all who are involved in the care of patients with the disease. Epidemiology, neuropathology, immunopathogenesis, clinical manifestations, diagnosis, and management are all thoroughly discussed based on current evidence and practice.
  • Cytokines and the brain 2008
    ScienceDirect
  • From important aspects of the physical examination to imaging studies to treatment options and dosage guidelines, this book provides a solid introduction to the evidence-based management of patients in the neurological intensive care unit. Succinct text in a highly accessible bullet-point format details the essentials of history-taking, physical examination, differential diagnosis, diagnostic evaluation, and treatments for a range of neurological problems in the critical care setting.
  • This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields.This volume explores interdisciplinary research on decision making taking a neural and behavioural approach *Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research *Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered *All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist.
  • Basic Principles of Deep Brain Stimulation / F. L. H. Gielen and G. C. Molnar -- Neural Circuits Affected by Deep Brain Stimulation for the Treatment of Psychiatric Disorders / Suzanne N. Haber and Benjamin D. Greenberg -- Mechanisms of Action of Deep Brain Stimulation for the Treatment of Psychiatric Disorders / J. Luis Lujan and Cameron C. McIntyre -- Deep Brain Stimulation in the Ventral Capsule/Ventral Striatum for the Treatment of Obsessive-Compulsive Disorder: Role of the Bed Nucleus of the Stria Terminalis / Loes Gabriëls and Bart Nuttin -- Deep Brain Stimulation in Obsessive-Compulsive Disorder Targeted at the Nucleus Accumbens / Pelle P. de Koning, Pepijn van den Munckhof, Martijn Figee, Rick Schuurman and Damiaan Denys -- What is the Role of the Subthalamic Nucleus in Obsessive-Compulsive Disorder? Elements and Insights from Deep Brain Stimulation Studies / William I. A. Haynes and Luc Mallet -- Obsessive-Compulsive Disorders in Animals / Christine Winter -- Subcallosal Cingulate Cortex Deep Brain Stimulation for the Treatment of Refractory Mood Disorders: Evidence and Challenges / Peter Giacobbe, Nir Lipsman and Andres M. Lozano -- Deep Brain Stimulation of the Human Reward System as a Putative Treatment for Refractory Major Depression / T. E. Schlaepfer, V. A. Coenen and B. H. Bewernick -- Depression in Humans: The Ventral Capsule/Ventral Striatum / Mayur Pandya, Andre Machado and Donald Malone -- Deep Brain Stimulation in Animal Models of Depression / Brian W. Scott, José N. Nobrega and Clement Hamani -- Deep Brain Stimulation in Tourette Syndrome / L. Ackermans, I. Neuner, J. Kuhn and V. Visser-Vandewalle -- Surgical Treatments for Drug Addictions in Humans / Bomin Sun and Wei Liu -- Manipulating Addictive Behaviour in Animal Models / Rolinka M. C. Schippers, Tommy Pattij and Taco J. De Vries -- Neuropsychiatric Side Effects of Deep Brain Stimulation in Parkinson's Disease / Christine Daniels and Jens Volkmann -- Psychiatric Aspects of Parkinson's Disease in Animal Models of Deep Brain Stimulation of the Subthalamic Nucleus / S. K. H. Tan, H. Hartung, V. Visser-Vandewalle, T. Sharp and Y. Temel -- Scientific Recordings in Deep Brain Stimulation / Michael X. Cohen -- Neurotransmitter Release During Deep Brain Stimulation / Osama A. Abulseoud, Emily J. Knight and Kendall H. Lee -- The Potential Role of Nonneuronal Cells in the Deep Brain Stimulation Mechanism: What Are Glia? What Are Their Functions? Could They Be Players in Deep Brain Stimulation? / Vinata Vedam-Mai, Michael S. Okun and Elly M. Hol -- Animal Studies in Deep Brain Stimulation Research / Matthijs G. P. Feenstra and Damiaan Denys -- Neuroimaging Deep Brain Stimulation in Psychiatric Disorders / Martijn Figee, Pepijn van den Munckhof, Rick Schuurman and Damiaan Denys -- Optogenetic Strategies for the Treatment of Neuropsychiatric Disorders: Circuit-Function Analysis and Clinical Implications / Daniel L. Albaugh and Garret D. Stuber -- Next-Generation Electrodes for Steering Brain Stimulation / H. C. F. Martens, M. M. J. Decré and E. Toader -- Future Applications: Nanotechniques / Russell J. Andrews, Jessica E. Koehne and Meyya Meyyappan -- Ethical Guidance for the Use of Deep Brain Stimulation in Psychiatric Trials and Emerging Uses: Review and Reflections / Emily Bell and Eric Racine -- History of "Psychiatric" Deep Brain Stimulation: A Critical Appraisal / Marwan I. Hariz.
  • Chronic electrical stimulation of the brain has become a standard surgical therapy for Parkinson's disease, with many studies demonstrating excellent outcomes without any serious complications. Recently this surgical intervention has also been applied to various other neurological diseases, such as involuntary movement disorders, intractable pain, and psychological conditions including depression and obsessive-compulsive disorder. This comprehensive, up-to-date textbook will meet the needs of all who wish to learn more about the application of deep brain stimulation and will provide a sound basis for safe and accurate surgery. The book comprises two main parts, the first of which presents relevant anatomical and functional background information on the basal ganglia, thalamus, and other brain structures as well as on the mechanism of brain stimulation. The second part describes clinical studies on deep brain stimulation, covering results in a range of movement disorders and psychiatric diseases and also important aspects of instrumentation and technique. The authors are outstanding scientists and experts in the field from across the world. This book will be welcomed by all young neurosurgeons, neurologists, psychiatrists, and other medical staff who are interested in electrical stimulation of the brain for the treatment of neurological disorders.
  • Introduction -- Overview of the nervous system -- The neurologic history -- The general physical examination -- General outline of the neurologic examination -- Gross and microscopic anatomy of the cerebral hemispheres -- Functions of the central cortex and regional cerebral diagnosis -- The mental status examination -- Disorders of speech and language -- Agnosia, apraxia, and related disorders of higher cortical function -- An overview of brainstem and cranial nerve anatomy -- The olfactory nerve -- The optic nerve -- The ocular motor nerves -- The trigeminal nerve -- The facial nerve -- The acoustic (vestibulocochlear) nerve -- The glossopharyngeal and vagus nerves -- The spinal accessory nerve -- The hypoglossal nerve -- Brainstem and multiple cranial nerve syndromes -- Overview of the motor system -- The motor unit level -- The spinal cord level -- The corticospinal (pyramidal) level -- The extrapyramidal level -- Motor strength and power -- Muscle tone -- Muscle volume and contour -- Abnormalities of movement -- Overview of the sensory system -- The exteroceptive sensations -- The proprioceptive sensations -- The interoceptive, or visceral, sensations -- Cerebral sensory functions -- Sensory localization -- Introduction to the reflexes -- The deep tendon or muscle stretch reflexes -- The superficial (cutaneous) reflexes -- Pathologic reflexes -- Postural and righting reflexes -- Associated movements -- Cerebellar function -- Gait and station -- The autonomic nervous system -- Peripheral neuroanatomy and focal neuropathies -- Neck and back pain -- Other musculoskeletal disorders -- The blood supply of the brain -- The ventricular system and the cerebrospinal fluid -- The examination in coma -- Miscellaneous neurologic signs -- Diagnostic reasoning and neurologic differential diagnosis.
  • Clinical investigations in primary care / de Souza, L.C. ... [et al.] -- The concept of mild cognitive impairment : relevance and limits in clinical practice / Michon, A. -- Pathological substrates of cognitive decline in Alzheimer's disease / Giannakopoulos, P. ... [et al.] -- Functional imaging in mild cognitive impairment and early Alzheimer's disease : is it pertinent? / Ibáñez, V.; Deiber, M.-P. -- Electrophysiological markers of rapid cognitive decline in mild cognitive impairment / Giannakopoulos, P. ... [et al.] -- The future : new methods of imaging exploration in Alzheimer's disease / Nordberg, A. -- Pharmacological interventions in primary care : hopes and illusions / Assal, F.; van der Meulen, M. -- Investigations in primary care / Poggesi, A.; Pantoni, L. -- The concept of vascular cognitive impairment / Erkinjuntti, T.; Gauthier, S. -- Defining the neuropathological background of vascular and mixed dementia and comparison with magnetic resonance imaging findings / Gold, G. -- Is it possible to treat vascular dementia? / Zekry, D. -- Dementia with Lewy bodies : clinical diagnosis and therapeutic approach / Gold, G. -- Significance of brain lesions in Parkinson disease dementia and Lewy body dementia / Jellinger, K.A. -- Delineating dementia with Lewy bodies : can magnetic resonance imaging help? / von Gunten, A.; Meuli, R. -- Pharmacotherapy of Parkinson disease dementia and Lewy body dementia / Gauthier, S. -- Clinical features and diagnosis of frontotemporal dementia / Kertesz, A. -- Neuropathological spectrum of frontal lobe dementias / Kövari, E. -- Frontotemporal dementia neuroimaging : a guide for clinicians / Seeley, W.W. -- Frontotemporal dementia : therapeutic interventions / Mendez, M.F.
  • This concise, pragmatic, pocket-sized book addresses neurological contributions to the diagnosis and management of dementia through a longitudinal examination of the work undertaken in a dedicated neurological dementia clinic. It covers the use of cognitive and non-cognitive screening instruments and their diagnostic utility and the use of other diagnostic investigations: neuroimaging, neurophysiology and neuropathology. The diagnostic mix is discussed in terms of both neuropsychological syndromes and neurological diagnoses, as is the use of conventional treatments for dementia and the impact of national directives (e.g. NICE, National Dementia Strategy) on day-to-day clinical practice. Dementia in Clinical Practice: A Neurological Perspective, Second Edition is an illustrated, practical resource for medical professionals involved in the assessment and management of dementia patients. It is of particular benefit to neurologists, psychiatrists, geriatricians, primary care practitioners and those working in the fields of neuropsychology, psychology, occupational therapy, speech and language therapy and nursing.
  • Dementias 2008
    ScienceDirect
  • Development of the dopamine systems in zebrafish / Jørn Schweitzer and Wolfgang Driever -- Dopamine systems in the forebrain / John W. Cave and Harriet Baker -- The role of Otx genes in progenitor domains of ventral midbrain / Antonio Simeone ... [et al.] -- Terminal differentiation of mesodiencephalic dopaminergic neurons : the role of Nurr1 and Pitx3 / Marten P. Smidt and J. Peter H. Burbach -- Foxa1 and Foxa2 transcription factors regulate differentiation of midbrain dopaminergic neurons / Siew-Lan Ang -- Transcriptional regulation of their survival : the engrailed homeobox genes / Horst H. Simon and Kambiz N. Alavian -- Neurotrophic support of midbrain dopaminergic neurons / Oliver von Bohlen und Halbach and Klaus Unsicker -- TGF in dopamine neuron development, maintenance, and neuroprotection / Eleni Roussa, Oliver von Bohlen und Halbach, and Kerstin Krieglstein -- Axon guidance in the dopamine system / Asheeta A. Prasad and R. Jeroen Pasterkamp -- Protocols for generating ES-cell-derived dopamine neurons / Sonja Kriks and Lorenz Studer -- Molecular and cellular determinants for generating ES-cell-derived dopamine neurons for cell therapy / -- Jan Pruszak and Ole Isacson.

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