Books by Subject
- 2014 Wileyedited by Ashutosh Tiwari and Anis N. Nordin.1. Frotiers for bulk nanostructured metals in biomedical applications -- 2. Stimuli-responsive materials used as medical devices in loading and releasing of drugs -- 3. Recent advances with liposomes as drug carriers -- 4. Fabrication, properties of nanoshells with controllable surface charge and its applications -- 5. Chitosan as an advanced healthcare material -- 6. Chitosan and low molecular weight chitosan: biological and biomedical applications -- 7. Anticipating behaviour of advanced materials in healthcare -- 8. Label-free biochips -- 9. Polymer MEMS sensors -- 10. Assembly of polymers/metal nanoparticles and their applications as medical devices -- 11. Combination of molecular imprinting and nanotechnology: beginning of a new horizon -- 12. Prussian blue and analogues: biosensing applications in health care -- 13. Efficiency of biosensors as new generation of analytical approaches at the biochemical diagnostics of diseases -- 14. Nanoparticles: scope in drug delivery -- 14. Smart polypeptide nanocarriers for malignancy therapeutics -- Index.
- 2014 Wileyedited by Ashutosh Tiwari, Biosensors and Bioelectronics Centre, Linkping University, Sweden."Advanced Healthcare Nanomaterials summarises the current status of knowledge in the fields of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, up and coming bio-engineering devices"-- Provided by publisher.
- 2010 Springeredited by Venkatram Prasad Shastri, George Altankov, Andreas Lendlein.Cell Adhesions and Signaling: A Tool for Biocompatibility Assessment / Roumen Pankov and Albena Momchilova -- Development of Provisional Extracellular Matrix on Biomaterials Interface: Lessons from In Vitro Cell Culture / George Altankov, Thomas Groth, Elisabeth Engel, Jonas Gustavsson and Marta Pegueroles, et al. -- Endothelial Progenitor Cells for Tissue Engineering and Tissue Regeneration Endothelial Progenitor Cells / Joyce Bischoff -- Dermal Precursors and the Origins of the Wound Fibroblast / Jeffrey M. Davidson -- Cell Based Therapies: What Do We Learn from Periosteal Osteochondrogenesis? / Peter J. Emans, Tim J. M. Welting and Venkatram Prasad Shastri -- Bioreactor Systems in Regenerative Medicine / Ivan Martin, Stefania A. Riboldi and David Wendt -- Biomimetic Approaches to Design of Tissue Engineering Bioreactors / Bojana Obradovic, Milica Radisic and Gordana Vunjak-Novakovic -- The Nature of the Thermal Transition Influences the Shape-Memory Behavior of Polymer Networks / Andreas Lendlein, Marc Behl and Stefan Kamlage -- Nanoengineered Systems for Regenerative Medicine Surface Engineered Polymeric Biomaterials with Improved Bio-Contact Properties / Todorka Vladkova and Natalia Krasteva -- Nanocomposites for Regenerative Medicine / Ryan Hoshi, Antonio R. Webb, Hongjin Qiu and Guillermo A. Ameer -- Role of Spatial Distribution of Matricellular Cues in Controlling Cell Functions / Daniela Guarnieri and Paolo A. Netti -- Materials Surface Effects on Biological Interactions / Josep A. Planell, Melba Navarro, George Altankov, Conrado Aparicio and Elisabeth Engel, et al. -- Chemical and Physical Modifications of Biomaterial Surfaces to Control Adhesion of Cells / Thomas Groth, Zhen-Mei Liu, Marcus Niepel, Dieter Peschel and Kristin Kirchhof, et al. -- Results of Biocompatibility Testing of Novel, Multifunctional Polymeric Implant Materials In-Vitro and In-Vivo / Dorothee Rickert, Rosemarie Fuhrmann, Bernhard Hiebl, Andreas Lendlein and Ralf-Peter Franke -- UFOs, Worms, and Surfboards: What Shapes Teach Us About Cell-Material Interactions / Julie A. Champion and Samir Mitragotri -- Nano-engineered Thin Films for Cell and Tissue-Contacting Applications / Richard F. Haglund -- Injectable Hydrogels: From Basics to Nanotechnological Features and Potential Advances / Biancamaria Baroli -- Polyelectrolyte Complexes as Smart Nanoengineered Systems for Biotechnology and Gene Delivery / Vladimir A. Izumrudov.
- Adverse effects of engineered nanomaterials : exposure, toxicology, and impact on human health. 1st ed.2012 ScienceDirectedited by Bengt Fadeel, Antonio Pietroiusti, Anna A. Shvedova.A. Engineered nanomaterials: hazard, exposure and safety assessment. Interactions with the human body / Renato Colognato ... [et al.] -- Exposure assessment / Antonio Bergamaschi, Ivo Iavicoli and Kai Savolainen -- Biomonitoring / Enrico bergamaschi and Andrea Magrini -- Critical evaluation of toxicity tests / Maria Dusinska ... [et al.] -- Computational approaches / Vidana Epa, Dave Winkler and Lang Tran -- Regulation and legislation / Maureen R. Gwinn and Birgit Sokull-Klüttgen -- B. Engineered nanomaterials: impact on human health. Respiratory system / Ken Donaldson and Craig Poland -- Cardiovascular system / Jennifer B. Raftis, Nicholas L. Mills and Rodger Duffin -- Neurological system / Sandra Ceccatelli and Giuseppe Bardi -- Immune system / Diana Boraschi and Albert Duschl -- Skin / Nancy A. Monteiro-Riviere and Francesca Larese Filon -- Gastrointestinal tract / Mark A. Jepson -- Reproductive toxicity / Karin Sørig Hougaard and Luisa Campagnolo -- Genotocicity and cancer / Shareen H. Doak, Ying Liu and Chunying Chen -- C. Biomedical applications of engineered nanomaterials. Diagnostic applications / Kalcheng and Zhen Cheng -- Therapeutic applications / Cyrill Bussy ... [et al.] -- Annex: synthesis of engineered nanomaterials / Muhammet S. toprak, Gulaim A. Seisenbaeva and Vadim G. Kessler.
- 2011 ScienceDirectGurumurthy Ramachandran, editor.The book represents a systematic look at nanoparticle risks within the paradigm of risk assessment, consider the limitations of this paradigm in dealing with the extreme uncertainties regarding many aspects of nanoparticle exposure and toxicity, and suggest new methods for assessing and managing risks in this context. It considers the occupational environment where the potential for human exposure is the greatest as well as the issues relevant to occupational exposure assessment (e.g., the exposure metric) and the evidence from toxicological and epidemiological studies. A chapter is devoted to how conventional risk assessment can be carried out for a candidate nanoparticle (e.g., carbon nanotubes), and the limitations that arise from this approach. The authors propose several alternate methods in another chapter including screening assessments and adapting the rich methodological literature on the use of experts for risk assessment. Another chapter deals with non-occupational populations, their susceptibilities, and life-cycle risk assessments. There is a chapter on current risk management and regulatory oversight frameworks and their adequacy. This chapter also includes a discussion of US and EU approaches to risk assessment, as well as corporate approaches.
- Atomic force microscopy, scanning nearfield optical microscopy and nanoscratching : application to rough and natural surfaces2006 SpringerG. Kaupp.
- Beta]-barrel channel proteins as tools in nanotechnology : biology, basic science and advanced applications2014 SpringerMarco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero.β-barrel outer membrane channel proteins (OMP) have great potential as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties without affecting the overall protein structure and stability. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. The β-barrel structure serviceability for the nano-material design will be its chief topic giving a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel to be adapted to a non-biological synthetic (i.e. polymer) environment, rendering it competitive with artificial non-biological nano-pores will be outlined specifically the design of a set of protein nano-channels with tailored geometry (diameter, length), conductance and functionality will be reported as a case study. In order to make this book a valuable source of information for both biotechnologists and other scientists interested in bio-nanotechnology an overview of the different steps involved in the nano-channel protein design and production will be reported. The scientific strategy from concept design, theoretical considerations, genetic engineering and large scale production, to system assembly and biophysical characterization with an overview on technological applications including membrane/polymersome technology, will be described.Also available: Print – 2014
- 2007 Springeredited by Warren C.W. Chan.Synthetic strategies to size and shape controlled nanocrystals and nanocrystal heterostructures / P. Davide Cozzoli and Liberato Manna -- Current approaches for engineering proteins with diverse biological properties / Isaac T.S. Li, Elizabeth Pham, and Kevin Truong -- Past, present, and future of gold nanoparticles / Travis Jennings and Geoffrey Strouse -- Multi-functional gold nanoparticles for drug delivery / Gang Han, Partha Ghosh, and Vincent M. Rotello -- Quantum dots for cancer molecular imaging / Xiaohu Gao and Shivang R. Dave -- Carbon nanostructures as a new high-performance platform for MR molecular imaging / Keith B. Hartman and Lon J. Wilson -- Magnetic nanoparticle assisted molecular MR imaging / Young-wook Jun, Jung-tak Jang, and Jinwoo Cheon -- Patterning metallic nanoparticles by DNA scaffolds / Rahul Chhabra ... [et al.] -- Liposomes in biology and medicine / Reto A. Schwendener -- Fluorescent nanoparticle for bacteria and DNA detection / Wenjun Zhao, Lin Wang, and Weihong Tan -- Dendrimer 101 / Lajos P. Balogh -- Quantum dots and other fluorescent nanoparticles: quo vadis in the cell? / Dusica Maysinger and Jasmina Lovri -- Toxicity studies of fullerenes and derivatives / Jelena Kolosnjaj, Henri Szwarc, and Fathi Moussa -- Toxicity studies of carbon nanotubes / Jelena Kolosnjaj, Henri Szwarc, and Fathi Moussa.Also available: Print – 2007
- 2014 ScienceDirectedited by Vladimir Uversky, Yuri Lyubchenko.Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin olig.
- 2013 Wileyedited by Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama, Fereidoon Shahidi.Nanotechnology / Hiroshi Muramatsu, Jun'ichi Wakayama, Kazumi Tsukamoto, Shigeru Sugiyama -- Applications of NMR to Biomolecular Systems of Interactions: An Overview / Shinya Hanashima, Yoshiki Yamaguchi -- Applications in Enhancing bioavailability and Controlling Pathogens. Bioavailability and Delivery of Nutraceuticals and Functional Foods Using Nanotechnology / Hailong Yu, Qingrong Huang -- Encapsulation of Bioactive Compounds in Micron/Submicron-Sized Dispersions Using Microchannel Emulsification or High-Pressure Homogenization / Marcos A Neves, Isao Kobayashi, Henelyta S Ribeiro, Katerina B Fujiu -- Nanometric-Size Delivery Systems for Bioactive Compounds for the Nutraceutical and Food Industries / Francesco Donsi, Mariarenata Sessa, Giovanna Ferrari -- Nanoemulsion Technology for Delivery of Nutraceuticals and Functional-Food Ingredients / Luz Sanguansri, Christine M Oliver, Fernando Leal-Calderon -- Nanotechnology and Nonpolar Active Compounds in Functional Foods: An Application Note / Philip J Bromley -- Safety, Toxicology and Regulatory Aspects. How Standards Inform the Regulation of Bio-nanotechnology / Martha E Marrapese -- FDA and Nanotech: Baby Steps Lead to Regulatory Uncertainty / Raj Bawa -- Toxicity and Environmental Risks of Nanomaterials: An Update / Paresh C Ray, Anant Kumar Singh, Dulal Senapati, Zhen Fan, Hongtao Yu -- Nanoparticle-Lung Interactions and Their Potential Consequences for Human Health / Craig A Poland, Martin J D Clift -- Future Directions in Bio-Nanotechnology Bio-Nanotechnology: A Journey Back to the Future / Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama, Fereidoon Shahidi.
- 2008 CRCnetBASEedited by Paul K. Chu and Xuanyong Liu.Electrohydrodynamic processing of micro- and nanometer biological materials / Yiquan Wu and Robert Lewis Clark -- Fabrication and function of biohybrid nanomaterials prepared via supramolecular approaches / Katsuhiko Ariga -- Polypyrrole nano- and microsensors and actuators for biomedical applications / Yevgeny Berdichevsky and Yu-Hwa Lo -- Processing of biosensing materials and biosensors / Yingchun Zhu, Yu Yang, and Yanyan Liu -- Synthetic and natural degradable polymeric biomaterials / Sanjukta Deb -- Electroactive polymers as smart materials with intrinsic actuation properties: new functionalities for biomaterials / Federico Carpi and Danilo De Rossi -- Blood contacting surfaces / Menno L.W. Knetsch -- Improving blood compatibility of biomaterials using a novel antithrombin-heparin covalent complex / Leslie Roy Berry and Anthony Kam Chuen Chan -- Surface modification of biomaterials using plasma immersion ion implantation and deposition / Xuanyong Liu, Ricky K.Y. Fu, Paul K. Chu -- Biomaterials for gastrointestinal medicine, repair and reconstruction / Richard M. Day -- Biomaterials for cartilage reconstruction and repair / Wojciech Swieszkowski ... [et al.]. Inorganic and composite bioactive scaffolds for bone tissue engineering / Q.Z. Chen, Oana Bretcanu, Aldo R. Boccaccini -- Design, fabrication and characterization of scaffolds via solid free-form fabrication techniques / Dietmar W. Hutmacher and Maria Ann Woodruff -- Control and monitoring of scaffold architecture for tissue engineering / Ying Yang ... [et al.] -- Rapid prototyping methods for tissue engineering applications / Giovanni Vozzi and Arti Ahluwalia -- Design and fabrication principles of electrospinning of scaffolds / Dietmar W. Hutmacher and Andrew K. Ekaputra -- Nanoparticles in cancer drug delivery systems / So Yeon Kim and Young Moo Lee -- Polymeric nano/microparticles for oral delivery of proteins and peptides / S. Sajeesh and Chandra P. Sharma -- Nanostructured porous biomaterials for controlled drug release systems / Yang Yang Li, Jifan Li, and Bunichiro Nakajima -- Inorganic nanostructures for drug delivery / Ying-Jie Zhu -- Self-assembly of nanostructures as biomaterials / Hua Ai, Yujiang Fan, and Zhongwei Gu --
- 2012 Wileyedited by Ashutosh Tiwari, Murugan Ramalingam, Hisatoshi Kobayashi, Anthony P.F. Turner.Application of the collagen as biomaterials / Kwangwoo Nam and Akio Kishida -- Biological and medical significance of nanodimensional and nanocrystalline calcium orthophosphates / Sergey V. Dorozhkin -- Layer-by-layer (LbL) thin film : from conventional to advanced biomedical and bioanalytical applications / Wing Cheung -- Polycaprolactone based nanobiomaterials / Narendra K. Singh and Pralay Maiti -- Bone substitute materials in trauma and orthopedic surgery properties and use in clinic / Esther M.M. Van Lieshout -- Surface functionalized hydrogel nanoparticles / Mehrdad Hamidi, Hajar Ashrafi, and Amir Azadi -- Utility and potential application of nanomaterials in medicine / Ravindra P. Singh [and others] -- Gold nanoparticle-based electrochemical biosensors for medical applications / Ulku Anik -- Impedimetric DNA sensing employing nanomaterials / Manel del Valle and Alessandra Bonanni -- Bionanocomposite matrices in electrochemical biosensors / Ashutosh Tiwari, Atul Tiwari -- Biosilica-nonocomposites-nanobiomaterials for biomedical engineering and sensing applications / Nikos Chaniotakis, Raluca Buiculescu -- Molecularly imprinted nanomaterial-based highly sensitive and selective medical devices / Bhim Bali Prasad and Mahavir Prasad Tiwari -- Immunosensors for diagnosis of cardiac injury / Swapneel R. Deshpande [and others] -- Ground-breaking changes in mimetic and novel nanostructured composites for intelligent-, adaptive-, and in vivo-responsive drug delivery therapies / Dipak K. Sarker -- Progress of nanobiomaterials for theranostic systems / Dipendra Gyawali [and others] -- Intelligent drug delivery systems for cancer therapy / Mousa Jafari [and others] -- The evolution of abdominal wall reconstruction and the role of nonobiotecnology in the development of intelligent abdominal wall mesh / Cherif Boutros, Hany F. Sobhi, and Nader Hanna -- Poly(polyol sebacate)-based elastomeric nanobiomaterials for soft tissue engineering / Qizhi Chen -- Electrospun nanomatrix for tissue regeneration / Debasish Mondal and Ashutosh Tiwari -- Conducting polymer composites for tissue engineering scaffolds / Yashpal Sharma, Ashutosh Tiwari, and Hisatoshi Kobayashi -- Cell patterning technologies for tissue engineering / Azadeh Seidi and Murugan Ramalingam.
- 2005 CRCnetBASEedited by Neelina H. Malsch.Converging technologies : nanotechnology and biomedicine / Mihail C. Roco -- Trends in biomedical nanotechnology programs worldwide / Mark Morrison and Ineke Malsch -- Nanotechnology and trends in drug delivery systems with self-assembled carriers / Kenji Yamamoto -- Implants and prostheses / Jeroen J.J.P. van den Beucken, X. Frank Walboomers, and John A. Jansen -- Diagnostics and high throughput screening / Aránzazu del Campo and Ian J. Bruce -- Nano-enabled components and systems for biodefense / Calvin Shipbaugh ... [et al.] -- Social and economic contexts : making choices in the development of biomedical nanotechnology / Ineke Malsch -- Potential risks and remedies / Emmanuelle Schuler.Also available: Print – 2005
- 2011 Springer Protocolsedited by Sarah J. Hurst.Biomedical nanotechnology / Sarah J. Hurst -- Multiplexed detection of oligonucleotides with biobarcoded gold nanoparticle probes / Jae-Seung Lee -- Molecular detection of biomarkers and cells using magnetic nanoparticles and diagnostic magnetic resonance / Jered B. Haun ... [et al.] -- Real-time quantum dot tracking of single proteins / Jerry C. Chang and Sandra J. Rosenthal -- Titanium dioxide nanoparticles in advanced imaging and nanotherapeutics / Tijana Rajh, Nada M. Dimitrijevic, and Elena A. Rozhkova -- Surface modification and biomolecule immobilization on polymer spheres or biosensing applications / Chris R. Taitt ... [et al.] -- Multivalent conjugation of peptides, proteins, and DNA to semiconductor quantum dots / Duane E. Prasuhn, Kimihiro Susumu, and Igor L. Medintz -- Single snO2 nanowire-based microelectrode / Jun Zhou ... [et al.] -- Biosensing using nanoelectromechanical systems / Ashish Yeri and Di Gao -- Nano "Fly Paper" technology for the capture of circulating tumor cells / Shutao Wang, Gwen E. Owens, and Hsian-Rong Tseng -- Polymeric nanoparticles for photodynamic therapy / Young-Eun Koo Lee and Raoul Kopelman -- Hydrogel templates for the fabrication of homogeneous polymer microparticles / Ghanashyam Acharya ... [et al.] -- Antibacterial application of engineered bacteriophage nanomedicines : antibody-targeted, chloramphenicol prodrug loaded bacteriophages for inhibiting the growth of staphylococcus aureus bacteria / Lilach Vaks and Itai Benhar -- Viruses as nanomaterials for drug delivery / Dustin Lockney, Stefan Franzen, and Steven Lommel -- Applications of carbon nanotubes in biomedical studies / Hongwei Liao ... [et al.] -- Electrospun nanofibrous scaffolds for engineering soft connective tissues / Roshan James ... [et al.] -- Peptide amphiphiles and porous biodegradable scaffolds for tissue regeneration in the brain and spinal cord / Rutledge G. Ellis-Behnke and Gerald E. Schneider -- Computational simulations of the interaction of lipid membranes with DNA-functionalized gold nanoparticles / One-Sun Lee and George C. Schatz -- Cytotoxic assessment of carbon nanotube interaction with cell cultures / Hanene Ali-Boucetta, Khuloud T. Al-Jamal, and Kostas Kostarelos -- Nanoparticle toxicology : measurements of pulmonary hazard effects following exposures to nanoparticles / Christie M. Sayes, Kenneth L. Reed, and David B. Warheit -- Nanoparticle therapeutics : FDA approval, clinical trials, regulatory pathways, and case study / Aaron C. Eifler and C. Shad Thaxton -- Legislating the laboratory? Promotion and precaution in a nanomaterials company / Robin Phelps and Erik Fisher -- Navigating the patent landscapes for nanotechnology : english gardens or tangled grounds / Douglas J. Sylvester and Diana M. Bowman -- Scientific entrepreneurship in the materials and life science industries / Jose Amado Dinglasan, Darren J. Anderson, and Keith Thomas -- Applying the marketing mix (5 Ps) to bionanotechnology / Michael S. Tomczyk -- Managing the "Known Unknowns" : theranostic cancer nanomedicine and informed consent / Fabrice Jotterand and Archie A. Alexander.
- 2013 Wileyedited by Murugan Ramalingam, Xiumei Wang, Guoping Chen, Peter Ma, and Fu-Zhai Cui.1. Biomimetic polysaccharides and derivatives for cartilage tissue regeneration -- 2. Biomimetic synthesis of self-assembled mineralized collagen-based composites for bone tissue engineering -- 3. Biomimetic mineralization of hydrogel biomaterials for bone tissue engineering -- 4. Biomimetic nanofibrous scaffolds for bone tissue engineering applications -- 5. Bioactive polymers and nanobiomaterials composites for bone tissue engineering -- 6. Strategy for a biomimetic paradigm in dental and craniofacial tissue engineering -- 7. Strategies to prevent bacterial adhesion on biomaterials -- 8. Nanostructured selenium- a novel biologically-inspired material for antibacterial medical device applications -- 9. Hydroxyapatite-biodegradable polymer nanocomposite microspheres toward injectable cell scaffold -- 10. Biomimetic ECM scaffolds prepared from cultured cells -- 11. Design and synthesis of phoreactive polymers for biomedical applications -- 12. The emerging applications of graphene oxide and graphene in tissue engineering -- 13. Biomimetic preparation and morphology control of mesoporous silica -- 14. Biomimetic materials for engineering stem cells and tissues.
- 2007Jian-Qin Liu, Katsunori Shimohara.
- 2009 CRCnetBASEedited by David E. Reisner.
- 2006 Springeredited by V. Renugopalakrishnan and Randolph V. Lewis.
- 2007Elisabeth S. Papazoglou, Aravind Parthasarathy.
- 2014 Wileyedited by Ashutosh Tiwari and Anthony P.F. Turner."This book provides detailed review chapters on a range of nanostructures such as nanoparticles, nanowires, nanotubes, nanoribbons, nanorods, nanobelts and nanosheets in the construction of biosensors with set applications of biosensors nanotechnology for biological and chemical analyses, food safety industry, biomedical diagnostics, clinical detection, and environmental monitoring. The authors provide a comprehensive view of cutting-edge research on advanced materials for healthcare technology and applications. The book is written for scientists, researchers, and clinicians from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering"--Provided by publisher.
- 2013 CRCnetBASEedited by Sang Hyun Cho, Sunil Krishnan.Basic principles of radiation therapy of cancers / Laurence Court and Radhe Mohan -- Biological principles of radiosensitization / Vikas Bhardwaj ... [et al.] -- Principles and applications of hyperthermia combined with radiation / Mark Hurwitz -- Synthesis and surface modification of nanomaterials for tumor targeting / Glenn Goodrich -- Safety concerns for nanomaterials in nanomedicinal applications / Qingxin Mu ... [et al.] -- Imaging with nanoparticles / Amit Joshi -- Optical microscopy of plasmonic nanoparticles / Varun P. Pattani and James Tunnell -- X-ray fluorescence computed tomography imaging of nanoparticles / Bernard L. Jones and Sang Hyun Cho -- Gold nanoparticle-mediated radiosensitization / Devika B. Chithrani -- Quantification of gold nanoparticle-mediated radiation dose enhancement / Sang Hyun Cho and Bernard L. Jones -- Semiconductor nanomaterials for radiotherapy / Ke Sheng -- Radioactive gold nanoparticle for tumor therapy / Raghuraman Kannan, Kattesh V. Katti, and Cathy Cutler -- Nanoparticles for the selective radioprotection of normal tissues / Jacob M. Berlin and Kathy A. Mason -- Gold nanoparticle-mediated hyperthermia in cancer therapy / Dev K. Chatterjee and Sunil Krishnan -- Magnetic resonance thermometry imaging for gold nanoparticle-mediated thermal therapy / R. Jason Stafford and John D. Hazle -- Modeling of plasmonic heat generation from gold nanoparticles / Francisco Reynoso and Sang Hyun Cho -- Carbon nanotubes for thermal therapy / Ravi N. Singh ... [et al.] -- Regulatory issues for clinical translations / J. Donald Payne -- Clinical translations of nanotechnology : present and future outlook / Dev K. Chatterjee, Sang Hyun Cho, and Sunil Krishnan.
- 2008 CRCnetBASESilvana Fiorito.
- 2013 Springer Protocolsedited by Volkmar Weissig, Tamer Elbayoumi, and Mark Olsen.Nanoparticle-GFP "chemical nose" sensor for cancer cell identification / Daniel F. Moyano and Vincent M. Rotello -- Method to map spatiotemporal pH changes in a multicellular living organism using a DNA nanosensor / Sunaina Surana and Yamuna Krishnan -- Simple method to visualize and assess the integrity of lysosomal membrane in mammalian cells using a fluorescent dye / Syed K. Sohaebuddin and Liping Tang -- Gold nanoparticle as a marker for precise localization of nano-objects within intracellular sub-domains / Valeriy Lukyanenko and Vadim Salnikov -- Immunoisolation of nanoparticles containing endocytic vesicles for drug quantitation / Ari Nowacek [and others] -- Methods for isolation and identification of nanoparticle-containing subcellular compartments / Ari Nowacek [and others] -- Permeabilization of cell membrane for delivery of nano-objects to cellular sub-domains / Valeriy Lukyanenko -- Method to encapsulate molecular cargo within DNA Icosahedra / Dhiraj Bhatia [and others] -- Delivery of plasmid DNA to mammalian cells using polymer-gold nanorod assemblies / James Ramos, Huang-Chiao Huang, and Kaushal Rege -- Lipophilic-formulated gold porphyrin nanoparticles for chemotherapy / Puiyan Lee and Kenneth K.Y. Wong -- Mitochondria-specific nano-emulsified therapy for myocardial protection against doxorubicin-induced cardiotoxicity / Amy Faulk, Volkmar Weissig, and Tamer Elbayoumi -- Formation of pit-spanning phospholipid bilayers on nanostructured silicon dioxide surfaces for studying biological membrane events / Indriati Pfeiffer and Michael Zach -- Characterization of nanoparticle-lipid membrane interactions using QCM-D / Rickard Frost and Sofia Svedhem -- Single-cell nanosurgery / Maxwell B. Zeigler and Daniel T. Chiu -- Single quantum dot imaging in living cells / Jerry C. Chang and Sandra J. Rosenthal -- Fabrication of fluorescent silica nanoparticles with aggregation-induced emission luminogens for cell imaging / Sijie Chen, Jacky W.Y. Lam, and Ben Zhong Tang -- Monitoring the degradation of reduction-sensitive gene carriers with fluorescence spectroscopy and flow cytometry / Constantin Hozsa, Miriam Breunig, and Achim Gopferich -- Quantification of intracellular mitochondrial displacements in response to nanomechanical forces displacements in response to nanomechanical forces / Yaron R. Silberberg and Andrew E. Pelling -- Imaging select mammalian organelles using fluorescent microscopy : application to drug delivery / Paul D.R. Dyer [and others] -- Real-time particle tracking for studying intracellular trafficking of pharmaceutical nanocarriers / Feiran Huang [and others] -- Interactions of nanoparticles with proteins : determination of equilibrium constants / Lennart Treuel and Marcelina Malissek -- Tracing the endocytic pathways and trafficking kinetics of cell signaling receptors using single QD nanoparticles / Katye M. Fichter and Tania Q. Vu -- Cellular internalization of quantum dots / Yue-Wern Huang [and others] -- Electrochemical scanning tunneling microscopy and spectroscopy for single-molecule investigation / Andrea Alessandrini and Paolo Facci -- Intracellular delivery of biologically active proteins with peptide-based carriers / Seong Loong Lo and Shu Wang -- Lipo-oligoarginine-based intracellular delivery / Jae Sam Lee and Ching-Hsuan Tung -- Fluorescent spherical monodisperse silica core-shell nanoparticles with a protein-binding biofunctional shell / Achim Weber, Marion Herz, and Gunter E.M. Tovar -- Direct quantification of PTD transduction using real-time monitoring / Mi-Sook Lee and Song Her -- Genotoxic assessment of carbon nanotubes / Olivera Neskovic [and others] -- Separation science : principles and applications for the analysis of bionanoparticles by asymmetrical flow field-flow fractionation (AF4) / Alexandre Moquin, Francoise M. Winnik, and Dusica Maysinger -- Polymersomes-mediated delivery of fluorescent probes for targeted and long-term imaging in live cell microscopy / Irene Canton and Giuseppe Battaglia -- Protocol for the preparation of stimuli-responsive gold nanoparticles capped with elastin-based pentapeptides / Vincent Lemieux, P. Hans H.M. Adams, and Jan C.M. van Hest.
- 2014 Wileyedited by Dr. Ravin Narain.General methods of bioconjugation -- Covalent and noncovalent bioconjugation strategies -- Polymer bioconjugates -- Bioconjugates based on poly(ethylene glycol)s and polyglycerols -- Synthetic polymer bioconjugate systems -- Natural polymer bioconjugate systems -- Dendrimer bioconjugates: synthesis and applications -- Organic nanoparticles based bioconjugates -- Bioconjugation strategies: lipids, liposomes, polymersomes, and microbubbles -- Organic nanoparticle bioconjugate: micelles, cross-linked micelles, and nanogels -- Carbon nanotubes and fullerene C60 bioconjugates -- Inorganic nanomaterials bioconjugates (metals, metal oxides--quantum dots, iron-oxide) -- Gold nanomaterials bioconjugates -- Methods for magnetic nanoparticle synthesis and functionalization -- Quantum dots bioconjugates -- Silica nanoparticle bioconjugates -- Polyhedral oligomeric silsesquioxanes (POSS) bioconjugates -- Cell-based, hydrogels/microgels and glyco-bioconjugates -- Cell-based bioconjugates -- Bioresponsive hydrogels and microgels -- Conjugation strategies used for the preparation of carbohydrate-conjugate vaccines -- Characterization, physico-(bio)chemical properties, and applications of bioconjugates -- Properties and characterization of bioconjugates -- Physico-chemical and biochemical properties of bioconjugates -- Applications of bioconjugates.
- v. 1-2, 2004 WileyC.N.R. Rao, A. Müller, A.K. Cheetham (eds.).v. 1. Nanomaterials : an introduction / C.N.R. Rao, A. Müller, A.K. Cheetham -- Strategies for the scalable synthesis of quantum dots and related nanodimensional materials / Paul O'Brien, N. Pickett -- Moving nanoparticles around : phase-transfer processes in nanomaterials synthesis / M. Sastry -- Mesoscopic assembly and other properties of metal and semiconductor nanocrystals / G.U. Kulkarni, P.J. Thomas, C.N.R. Rao -- Oxide nanoparticles / R. Seshadri -- Sonochemistry and other novel methods developed for the synthesis of nanoparticles / Y. Mastai, A. Gedanken -- Solvothermal synthesis of non-oxide nanomaterials / Y.T. Qian, Y.L. Gu, J. Lu -- Nanotubes and nanowires / A. Govindaraj, C.N.R. Rao -- Synthesis, assembly and reactivity of metallic nanorods / C.J. Murphy ... [et al.] -- Oxide-assisted growth of silicon and related nanowires : growth mechanism, structure and properties / S.T. Lee, R.Q. Zhang, Y. Lifshitz -- v. 2. Electronic structure and spectroscopy of semiconductor nanocrystals / S. Sapra, D.D. Sarma -- Core-shell semiconductor nanocrystals for biological labeling / R.E. Bailey, S. Nie -- Large semiconductor molecules / J.F. Corrigan, M.W. DeGroot -- Oxomolybdates : from structures to functions in a new era of nanochemistry / A. Müller, S. Roy -- Nanostructured polymers / S. Ramakrishnan -- Recent developments in the chemistry and chemical applications of porous silicon / J.M. Schmeltzer, J.M. Buriak -- Nanocatalysis / S. Abbet, U. Heiz -- Nanoporous materials / A.K. Cheetham, P.M. Forster -- Photochemistry and electrochemistry of nanoassemblies / P.V. Kamat -- Electrochemistry with nanoparticles / S. Devarajan, S. Sampath -- Nanolithography and nanomanipulation / A.K. Raychaudhuri.
- 2008 CRCnetBASEedited by Kiichi Fukui, Tatsuo Ushiki.Mechanical approaches to elucidate mechanisms of chromosome condensation at the nano- and microlevels / Kazushige Kawabata ... [et al.] -- Development of novel AFM probes for chromosome manipulation / Masato Saito, Gen Hashiguchi and Eiichi Tamiya -- Microchamber array-based sequence-specific DNA detection from a single chromosome via trace volume PCR / Masato Saito and Eiichi Tamiya -- On-chip chromosome sorter using electric and magnetic fields / Takahito Inoue ... [et al.] -- Fluorescence microscopy for analysis of chromosome dynamics / Sachihiro Matsunaga -- Fluorescence in situ hybridization (FISH) as a tool for comparative genomics: application of FISH to studies of chromosome evolution in vertebrates / Yoichi Matsuda ... [et al.] -- Immunocytochemistry for analyzing chromosomes / Osamu Hoshi ... [et al.] -- Proteome analysis of human metaphase chromosomes / Kiichi Fukui and Susumu Uchiyama -- Antipeptide antibodies for examining the conformation and molecular assembly of an intracellular protein / Masatoshi Nakagawa ... [et al.] -- Structure and interactions of the imitation SWI-type chromatin-remodeling complex, ATP-dependent chromatin-assembly facter / Tadayasu Ohkubo ... [et al.] -- Dynamic and functional analysis of chromosomal proteins / Nobuko Ohmido ... [et al.] -- Development of a sustainable chromosome imaging database / Kenji Taniguchi ... [et al.] -- Image database and image analysis of chromosome information / Shin-ichi Toyabe ... [et al.]. Transmission and scanning electron microscopy of mammalian metaphase chromosomes / Sumire Inaga, Keiichi Tanaka and Tatsuo Ushiki -- Atomic force microscopy of human chromosomes in relation to their higher-order structure / Osamu Hoshi, Daisuke Fukushi and Tatsuo Ushiki -- Mechanism of higher-order chromatin folding revealed by AFM observation of in vitro reconstituted chromatin / Kohji Hizume ... [et al.] -- Scanning near-field optical/atomic force microscopy as a tool for simultaneous specification of chromosome topography and particular gene location on the nanometer scale / Motoharu Shichiri ... [et al.] -- Isolation of human and plant chromosomes as nanomaterials / Susumu Uchiyama, Tomoyuki Doi and Kiichi Fukui --
- 2014 CRCnetBASESara Brenner, MD, MPH, editor.Nanotechnology applications for infectious diseases / Ellis H. Tobin -- Nanotechnology applications in dermatology / David Schairer, Jason Chouake, Adnan Nasir, and Adam Friedman -- Nanotechnology applications in ophthalmology / Eman Elhawy and John Danias -- Nanotechnology applications in urology / Himanshu Aggarwal and Barry A. Kogan -- Nanotechnology applications in preventive medicine and public health / Julielynn Wong and Sara Brenner -- Nanotechnology applications in vascular medicine and surgery / Manish Mehta, Philip S.K. Paty, W. John Byrne, Yaron Sternbach, John B. Taggert, and Kathleen J. Ozsvath -- Therapeutic applications and targeted delivery of nanomedicines and nanopharmaceutical products / Heidi M. Mansour and Chun-Woong Park.
- 2013 Wileyedited by Takafumi Ueno, Yoshihito Watanabe.pt. I. Coordination chemistry in native protein cages -- pt. II. Design of metalloprotein cages -- pt. III. Coordination chemistry of protein assembly cages -- pt. IV. Applications in biology -- pt. V. Applications in nanotechnology -- pt. VI. Coordination chemistry inspired by protein cages.
- v. 1-5, 2004 CRCnetBASEedited by James A. Schwarz, Cristian I. Contescu, Karol Putyera.v. 1. A-C -- v. 2. D-Mec -- v. 3. Met-Nano -- v. 4. Near-R -- v. 5. S-XYZ.
- 2012 Wileyedited by Yiyun Cheng.Dendrimer Chemistry: Supramolecular Perspectives and Applications / Charles N Moorefield, Sujith Perera, George R Newkome -- Physicochemical Properties of Dendrimers and Dendrimer Complexes / Toyoko Imae -- The Use of Dendrimers to Optimize the Physicochemical and Therapeutic Properties of Drugs / Nicole Stieger, Wilna Liebenberg, Marique E Aucamp, Melgardt M De Villiers -- Biological Properties of Phosphorus Dendrimers / Anne-Marie Caminade, Jean-Pierre Majoral -- Dendrimer-Based Prodrugs: Synthesis and Biological Evaluation / Mohammad Najlah, Zhengyuan Zhou, Antony D'Emanuele -- Improving the Biocompatibility of Dendrimers in Drug Delivery / Yiwen Li, Libo Zhao, Yiyun Cheng -- Degradable Dendrimers for Drug Delivery / Marc Gingras, Myriam Roy -- Design of Stimuli-Responsive Dendrimers for Biomedical Purposes / Chie Kojima -- Dendrimer-Based Gene Delivery Systems: Administration Routes and Evaluation / M J Santander-Ortega, I F Uchegbu, A G -- Triazine Dendrimers for DNA and siRNA Delivery: Progress, Challenges, and Opportunities / Meredith A Mintzer, Olivia M Merkel, Thomas Kissel, Eric E Simanek -- Dendrimer-Coated Carbohydrate Residues as Drug Delivery Trojan Horses in Glycoscience / Yoann M Chabre, Reň Roy -- Nuclear Magnetic Resonance Techniques in the Analysis of Pamam Dendrimer-Based Drug Delivery Systems / Xueyan Feng, Kun Yang, Jingjing Hu, Tongwen Xu, Yiyun Cheng -- Dendrimer-Based Medical Nanodevices for Magnetic Resonance Imaging Applications / Hongdong Cai, Mingwu Shen, Xiangyang Shi -- Dendrimer-Related Nanoparticle System for Computed Tomography Imaging / Chen Peng, Xiangyang Shi -- Index -- Wiley Series in Drug Discovery and Development.
- Development of techniques for three-dimensional super-resolution fluorescence microscopy and their application to biological systems2011Michael Anthony Thompson.Fluorescence microscopy is one of the most widely used tools in cell biology due its intrinsically high detection sensitivity coupled with the ability to genetically label proteins and other cellular structures with fluorescent tags. However, the resolution of fluorescence microscopy has historically been limited to about 200 nm laterally and 800 nm axially because of the diffraction limit of visible light. In the past five years, imaging below the diffraction limit ("super-resolution imaging") by localizing single fluorophores, one at a time (1-3), has opened a wide a variety of new biological systems for study. This Dissertation is a collection of both techniques for two and three dimensional super-resolution imaging as well as applications in bacterial and yeast imaging. References 1. Betzig E, et al (2006) Imaging intracellular fluorescent proteins at nanometer resolution. Science 313: 1642-1645. 2. Hess ST, Girirajan TPK & Mason MD (2006) Ultra-high resolution imaging by fluorescence photoactivation localization microscopy. Biophys J 91: 4258-4272. 3. Rust MJ, Bates M & Zhuang X (2006) Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat Methods 3: 793-795.
- 2013 SpringerVolker A. Erdmann, Jan Barciszewski, editors.DNA and RNA nanobiotechnologies have currently reached the status of one of the most dynamic research areas in the field of drug delivery in molecular medicine. Scientists and bio-engineers are creating totally new nanometer-scale structures with unique biological properties for a wide range of medical applications. The book, written by world-leading scientists in this new field, gives an overview of various aspects and applications of DNA and RNA nanotechnologies. These include the design and synthesis of DNA and RNA nanostructures with the aim of using them for different kinds of drug deliveries, for genetic immunization, for metabolite and nucleic acid detection, gene regulation, siRNA delivery for cancer treatment, and even analytical and therapeutic applications of aptamer-based nanoparticles. This volume will be of interest not only to graduate students and researchers in the field of molecular medicine and molecular biology, but also to chemists interested in the biological fields. As a matter of fact, the book contains so many new and unique approaches to this area of molecular medicine that it may inspire the interested reader to undertake research into nucleic acid nanotechnologies.
- 2011 Springer Protocolsedited by Giampaolo Zuccheri and Bruno Samori.Synthesis and characterization of self-assembled DNA nanostructures / Chenxiang Lin [and others] -- Protocols for self-assembly and imaging of DNA nanostructures / Thomas L. Sobey and Friedrich C. Simmel -- Self-assembly of metal-DNA triangles and DNA nanotubes with synthetic junctions / Hua Yang [and others] -- DNA-templated Pd conductive metallic nanowires / Khoa Nguyen, Stephane Campidelli, and Arianna Filoramo -- Method to map spatiotemporal pH changes inside living cells using a pH-triggered DNA nanoswitch / Souvik Modi and Yamuna Krishnan -- Control of helical handedness in DNA and PNA nanostructures / Roberto Corradini [and others] -- G-quartet, G-quadruplex, and G-wire regulated by chemical stimuli / Daisuke Miyoshi and Naoki Sugimoto -- Preparation and atomic force microscopy of quadruplex DNA / James Vesenka -- Synthesis of long DNA-based nanowires / Alexander Kotlyar -- G-wire synthesis and modification with gold nanoparticle / Christian Leiterer, Andrea Csaki, and Wolfgang Fritzsche -- Preparation of DNA nanostructures with repetitive binding motifs by rolling circle amplification / Edda Rei7, Ralph Holzel, and Frank F. Bier -- Controlled confinement of DNA at the nanoscale : nanofabrication and surface bio-functionalization / Matteo Palma [and others] -- Templated assembly of DNA origami gold nanoparticle arrays on lithographically patterned surfaces / Albert M. Hung and Jennifer N. Cha -- DNA-modified single crystal and nanoporous silicon / Andrew Houlton [and others] -- Atomic force microscopy as a lithographic tool : nanografting of DNA nanostructures for biosensing applications / Matteo Castronovo and Denis Scaini -- Trapping and immobilization of DNA molecules between nanoelectrodes / Anton Kuzyk, J. Jussi Toppari, and Paivi Torma -- DNA contour length measurements as a tool for the structural analysis of DNA and nucleoprotein complexes / Claudio Rivetti -- DNA molecular handles for single-molecule protein-folding studies by optical tweezers / Ciro Cecconi [and others] -- Optimal practices for surface-tethered single molecule total internal reflection fluorescence resonance energy transfer analysis / Matt V. Fagerburg and Sanford H. Leuba -- Engineering mononucleosomes for single-pair FRET experiments / Wiepke J.A. Koopmans, Ruth Buning, and John van Noort -- Measuring DNA-protein binding affinity on a single molecule using optical tweezers / Micah J. McCauley and Mark C. Williams -- Modeling nanopores for sequencing DNA / Jeffrey R. Comer, David B. Wells, and Aleksei Aksimentiev.
- 2012 WileyJoachim H. Wendorff, Seema Agarwal, Andreas Greiner."Electrospinning is from the academic as well as technical perspective presently the most versatile technique for the preparation of continuous nanofibers obtained from numerous materials including polymers, metals, and ceramics. Shapes and properties of fibers can be tailored according to the demand of numerous applications including filtration, membranes, textiles, catalysis, reinforcement, or biomedicals. This book summarizes the state-of-the art in electrospinning with detailed coverage of the various techniques, material systems and their resulting fi ber structures and properties, theoretical aspects and applications. Throughout the book, the current status of knowledge is introduced with a critical view on accomplishments and novel perspectives. An experimental section gives hands-on guidance to beginners and experts alike."-- Provided by publisher.
- 2012 Future Mededitors, Joseph R. Lakowicz, Jian Zhang.Emerging applications of colloidal noble metals in cancer nanomedicine / Jian Zhang & Joseph R. Lakowicz -- Particle characterizations and synthesis methods / Jian Zhang & Joseph R. Lakowicz -- Diagnostics and treatments / Anna M. Sitarski, Jeremy L. Grant, Sanjeev Kumar Kandpal & Michael D. Mason -- Photothermal agents for cell theranostics / Dmitri O. Lapotko -- Drug delivery carriers / Marie-Christine Daniel -- Other applications and future directions / Ismail Ocsoy, Tao Chen & Weihong Tan -- Applications of noble metal nanoparticles in fluorescence sensing / Yi Fu -- Index.
- 2014 Wileyedited by Rebecca A. Bader, David A. Putnam.Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-
- 2006 Springerby Martina Newell-McGloughlin and Edward Re.
- FAO/WHO Expert meeting on the application of nanotechnologies in the food and agriculture sectors : potential food safety implications : meeting report.2010 WHO"The advent of nanotechnology has unleashed enormous prospects for the development of new products and applications for a wide range of industrial and consumer sectors. The new technological developments have already opened up a multibillion dollar industry in recent years, the global market impact of which is expected to reach US$1 trillion by 2015, with around 2 million workers. While the majority of manufacturing and use of nanoscale materials occurs in the United States, the European Union, with its around 30 percent global share of the sector, is not lagging far behind in this field. Like other sectors, nanotechnology promises to revolutionize the whole food chain--from production to processing, storage, and development of innovative materials, products and applications. Although the potential applications of nanotechnoloy are wide ranging, the current applications in the food and agricultural sectors are relatively few, because the science is still newly emergent. An overview of more than 800 nanotechnology-based consumer products that are currently available worldwide, suggests that only around 10 percent of these are foods, beverages and food packaging products. However, nanotechnology-derived products and applications in these sectors have been steadily increasing in recent years, and are predicted to grow rapidly in the future. This is because the new technologies have a great potential to address many of the industry's current needs." - p. 3Also available: Print – 2010
- 2006 CRCnetBASEedited by Aleksandar M. Spasic, Jyh-Ping Hsu.
- From solid state to soft matter : photonic nanocavities as advanced optoelectronic devices and single-cell biomedical probes2013Gary Shambat.Photonic nanocavities are wavelength-scale dielectric structures that possess remarkable properties due to their intrinsic small sizes and high quality factors. Simply by modifying the device materials and optical properties, one can realize nanocavities for diverse applications ranging from lasers to quantum optics and even biosensing. In this dissertation work, two drastically different functions of nanocavities are presented, both of which make them more practical for real-world adoption. The first part of this dissertation will focus on engineered optical devices for interconnect applications in computing and communications. We have shown that heavily doped germanium on silicon can be used as a CMOS-compatible light source with peak emission at 1.5 microns. Microdisk resonators were fabricated and shown to sustain cavity resonances through both photoluminescence (PL) and electroluminescence (EL) measurements. To access these microresonators, we developed a coupling process using a tapered optical fiber and further showed the versatility of these fibers by using them to tune the cavity wavelength. High performance optical sources were then demonstrated in a gallium arsenide platform containing embedded quantum dots (QDs). We have developed a new platform for efficiently driving photonic crystal (PC) cavities using a lithographically defined, lateral p-i-n junction. With our lateral junction we have demonstrated a world record low threshold laser with a threshold power of only 208 nW at 50K. At room temperature we find that these same devices behave as ultra-fast light-emitting diodes which can be directly modulated at up to 10 GHz with operational energies below 1 fJ/bit. Additional active photonic devices incorporating a lateral junction such as electro-optic modulators and photodetectors were also created using this same platform. The second part of this dissertation describes the demonstration of a whole new class of tools geared towards biomedical photonics that marry PC cavities to the tips of optical fibers. The form factor of the optical fiber lends itself to operation of the tool in exotic environments never before accessible to a nanocavity. Fiber-cavity hybrid devices were constructed using a custom epoxy-based assembly procedure which successfully relocates the small semiconductor templates containing nanocavities. The completed device, called a fiberPC, was then used as a sensor to detect gold nanoparticles through optical readout. We have used our probes to interrogate single human prostate cells with internalized PC cavities showing, for the first time, resonant photonic modes inside biological cells. The beams can be loaded in cells and tracked for days at a time, with cells undergoing regular division and migration. Furthermore, we present in vitro label-free protein sensing with our probes as a path towards quantitative, real-time biomarker detection in single cells. The developed tool may find future applications in drug screening, cancer detection, and fundamental cell biology.
- 2013 SpringerIjeoma F. Uchegbu, Andreas G. Schätzlein, Woei Ping Cheng, Aikaterini Lalatsa, editors.Nanoscience and nanotechnology overview -- Liposome preparation and characterization -- Solid polymeric nanoparticles -- Lipid nanoparticles -- Polymeric vesicles -- Low molecular weight amphiphile micelles -- Polymeric micelles -- Niosomes -- Quantum dots -- Magnetic particles -- Drug nanoparticles -- Polymeric pro-drugs -- Therapeutic Applications of pharmaceutical nanosystems -- Drug solubilisation -- Gene therapy -- Chemotherapy -- Tissue engineering -- Anti-infectives -- Vaccination -- Anti-arthritic drugs -- Imaging agents -- Commercial exploitation of pharmaceutical nanosystems -- Future perspectives -- Multiple Choice -- Problem Sets -- Case Studies -- Suggested Reading.
- Giant magnetoresistive nanosensors for ultrasensitive in vitro diagnostics and biomolecular kinetics2011Richard S. Gaster.Nanotechnology has the unique capability of manipulating and sensing matter at the molecular scale with unprecedented speed, sensitivity, and throughput. The medical application of nanotechnology, nanomedicine, has leveraged nanoscience tools for the advancement of medical diagnostics, therapy, and basic science research. In this work, arrays of magnetically responsive nanosensors, originally developed for use as read heads in computer hard disk drives, have been utilized to achieve in-depth proteomic studies for the advancement of medical diagnostics and therapy. In particular, this dissertation will focus on the following four topics of applying magnetic nanotechnology to science and medicine. First, the application of magnetic nanosensor arrays to early cancer diagnostics and monitoring response to chemotherapy. The utility of magnetic nanosensors as a molecular diagnostics tool capable of profiling a patient's disease state and leveraging a patient's unique molecular signature will be demonstrated. Second, this report will discuss a novel mathematical model expressly developed to describe the kinetic interactions of magnetically labeled biomolecules binding to capture agents immobilized on a surface. Third, a novel autoassembly immunoassay capable of screening for antibody cross-reactivity in a high-density, high-fidelity, and rapid manner will be described. Finally, this report will address the utility of the autoassembly immunoassay in conjunction with a miniaturized magnetic nanosensor platform for point-of-care diagnostics in a cost-effective and easy-to-use (e.g. wash-free) process that can make a significant contribution to global health.
- 2006 CRCnetBASEKimball Nill.
- 2011Drew Alexander Hall.Nanotechnology has had a transformative effect on medical diagnostics due to the influx of new sensing modalities and transducers. Magnetic nanotechnologies, in particular, have shown significant potential in several areas of nanomedicine such as imaging, therapeutics, and early disease detection. Giant magnetoresistive spin-valve (GMR SV) sensors, commonly used in hard disk drives, coupled with magnetic nanotags have shown great promise as biosensors. In this work, we present several custom designed circuit interface and readout systems tailored to specific application spaces and their unique needs. Taken together, we have demonstrated that innovative electronic circuits play an indispensable role in unlocking the tremendous potential of nanosensors in the biomedical arena. The first system was designed for ultrasensitive early cancer diagnostics and built using off-the-shelf components for an 8x8 array of GMR SV sensors. At the core of this design, we demonstrate a new circuit architecture based on a transimpedance amplifier (TIA) with a carrier suppression technique to reduce the dynamic range requirement and a multiplexing scheme to reduce the readout time. This system is capable of real-time, multiplex detection with a detection limit of 5 femtomolar (fM) and over 6 orders of linear dynamic range. The second system is a miniaturized, portable platform called the nanoLAB. Although there is a growing need for point-of-care (POC) testing for global health, the current options are bulky, slow, expensive, and often not sensitive. The nanoLAB addresses these needs and pushes the state of the art with sensitive 8-plex detection using a wash-free assay that can be run by anyone, anywhere. This platform was tested and validated using human immunodeficiency virus (HIV) biomarkers with detection down to 50 fM in as little as 15 minutes. We also show how a GMR SV biosensor can be integrated into a continuous time sigma delta modulator. This proof-of-concept hybrid sigma delta modulator has a peak SNR of 99.3 dB and a dynamic range of over 92 dB in a 1 kHz bandwidth using the sensor as part of the first integrator. The carrier suppression and multiplexing concepts were also incorporated into the hybrid sigma delta modulator. Lastly, we conclude by describing an integrated platform for a large 16x16 array of GMR SV sensors implemented in a 0.18 [mu]m CMOS technology. Arranged like an imager chip, each of the 16 column level readout channels contains an analog front-end and an analog-to-digital converter. Each readout channel occupies less than 0.2 mm^2 of chip area and consumes 3.4 mW of power. This system is designed as a replacement for optical protein microarrays while being fully quantitative and providing real-time readout.
- 2010 CRCnetBASEeditors, Vladimir Torchilin, Mansoor M. Amiji.pt. 1. Organic nanostructures -- pt. 2. Inorganic nanostructures.
- 2012 SpringerKewal K. Jain.Nanotechnologies -- Nanotechnologies for Basic Research Relevant to Medicine -- Nanomolecular Diagnostics -- Nanopharmaceuticals -- Role of Nanotechnology in Biological Therapies -- Nanodevices and Techniques for Clinical Applications -- Nanooncology -- Nanoneurology -- Nanocardiology -- Nanopulmonology -- Nanoorthopedics -- Nano-ophthalmology -- Nanomicrobiology -- Miscellaneous Healthcare Applications of Nanobiotechnology -- Nanobiotechnology and Personalized Medicine -- Nanotoxicology -- Ethical and Regulatory Aspects of Nanomedicine -- Research and Future of Nanomedicine.
- 2014 Wileyeditors, Saura C. Sahu, Daniel A. Casciano.
- 2014 CRCnetBASEedited by Ioannis S. Vizirianakis.This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigila.
- Handbook of safety assessment of nanomaterials : from toxicological testing to personalized medicine2015 CRCnetBASEedited by Bengt Fadeel.1. Nanomedicine(s) and their regulation / Ruth Duncan -- 2. Nanotoxicology : focus on nanomedicine / Helinor Johnston, Ali Kermanizadeh, and Vicki Stone -- 3. Nanomaterial characterization for toxicity testing / David B. Warheit and Christie M. Sayes -- 4. The synthetic and biological identities of nanomaterials / Bengt Fadeel and Wolfgang J. Parak -- 5. Nanotoxicology : the case for in vitro tests / Thomas Hartung -- 6. Nanotoxicology : the case for in vivo studies / David Y. Lai and David B. Warheit -- 7. Predictive nanotoxicology : in silico approaches / Enrico Burello -- 8. Physiologically based nanomaterial pharmacokinetic models / Jim E. Riviere -- 9. Immunotoxicity of nanomaterials / Barbara Lettiero, Z. Shadi Farhangrazi, and S. Moein Moghimi -- 10. Complement activation by nanomaterials / Janos Szebeni -- 11. Biodegradation of carbon-based nanomaterials / Cyrill Bussy, Alberto Bianco, Maurizio Prato, and Kostas Kostarelos -- 12. Genotoxicity and carcinogenicity of nanomaterials / Kee Woei Ng, Yun Zhao, Mustafa Hussain Kathwala, Sijing Xiong, Chit Fang Cheok, and Say Chye Joachim Loo -- 13. Pulmonary and cardiovascular toxicity of nanomaterials / Flemming R. Cassee and Vincent Castranova -- 14. Neurotoxicity of nanomaterials / Hari Shanker Sharma and Aruna Sharma -- 15. Dermatotoxicity of nanomaterials / Nancy A. Monteiro-Riviere and Jim E. Riviere -- 16. Reproductive toxicity of nanomaterials / Margaret Saunders, Gary Hutchison, and Sara Correia Carreira -- 17. Nanomedicine : ethical considerations / Todd Kuiken.
- 2014 CRCnetBASEedited by Varvara Karagkiozaki, Stergios Logothetidis.1. Introduction in clinical nanomedicine / Stergios Logothetidis -- 2. Nanomedicine combats atherosclerosis / Varvara Karagkiozaki -- 3. Nanomedicine advancements in cancer diagnosis and treatment / Eric Michael Bratsolias Brown -- 4. Nanomedicine and blood diseases / Emmanouil Nikolousis -- 5. Nanomedicine and orthopaedics / Fares E. Sayegh -- 6. Nanopharmaceutics : structural design of cationic gemini surfactant-phospholipid-DNA nanoparticles for gene delivery / Marianna Foldvari -- 7. Nanomedicine and embryology : causative embryotoxic agents which can pass the placenta barrier and induce birth defects / Elpida-Niki Emmanouil-Nikoloussi -- 8. Nanomedicine and HIV/AIDS / Enikő R. Tőke and Julianna Lisziewicz -- 9. Nanoscaffolds and other nano-architectures for tissue engineering-related applications / Paraskevi Kavatzikidou and Stergios Logothetidis -- 10. Biocompatible 2D and 3D polymeric scaffolds for medical devices / Masaru Tanaka -- 11. Regenerative dentistry : stem cells meet nanotechnology / Lucía Jiménez-Rojo, Zoraide Granchi, Anna Woloszyk, Anna Filatova, Pierfrancesco Pagella, and Thimios A. Mitsiadis -- 12. Toxicity and genotoxicity of metal and metal oxide nanomaterials : a general introduction / Mercedes Rey, David Sanz, and Sergio E. Moya -- 13. Analogies in the adverse immune effects of wear particles, environmental particles, and medicinal nanoparticles / Eleonore Fröhlich.
- 2013 Springer Protocolsedited by Yaron Shav-Tal.As imaging technologies and approaches have evolved, the scope of certain imaging techniques has moved far beyond the production of purely illustrative images or appealing time-lapse movies to providing the scientist with a rich range of ways to measure and quantify the biological process and outcome of gene expression. In Imaging Gene Expression: Methods and Protocols, expert authors offer up-to-date approaches and protocols that scientists in the field have developed, which would benefit the broader scientific community. Divided in three convenient parts, this detailed book covers the output of a gene, namely the RNA molecules that are transcribed from the gene and the way by which these molecules can be tracked or quantified in fixed or living cells, protocols that focus on the gene, DNA, or chromatin, as well as a variety of ways by which nuclear processes intertwined with gene expression can be followed and quantified in living cells as well as approaches for studying several sub-nuclear structures found in eukaryotic cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective subjects, lists of materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Imaging Gene Expression: Methods and Protocols will serve researchers working toward imaging in the context of complete organisms.
- 2010 SpringerBert Gordijn, Anthony Mark Cutter, editors.This volume assembles an interdisciplinary team of leading academics, industry figures, policymakers and NGOs to consider the legal, ethical and social issues that are raised by innovations in nanoscience and nanotechnology. By bringing together international experts from a diverse range of fields this volume addresses the implications and impact that nanotechnology has on society. Through the exploration of six key themes the contributors analyse both the impact of nanotechnology and the emergence of the concept of nanoethics. Each section includes authors from both sides of the political and scientific divide incorporating both positive and negative perspectives on nanotechnology, as well as including discussions of associated concepts such as converging technologies. The result provides for the widest and most balanced discussion of these issues to date.
- Infectious diseases and nanomedicine. I-II : first International Conference (ICIDN-2012), Dec. 15-18, 2012, Kathmandu, Nepal2014 Springerv. 2 SpringerRameshwar Adhikari, Santosh Thapa, editors.The volumes address the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences.Also available: Print – v. 1-2, 2014.
- 2014 ScienceDirectGerardo Caruso, Lucia Merlo, Maria Caffo.
- 2012 SpringerTobias Knopp, Thorsten M. Buzug ; with the collaboration of Jörn Borgert and Bernhard Gleich.How Magnetic Particle Imaging Works -- How to Build an MPI Scanner -- Prior to Reconstruction - The System Function -- From Data to Images: Reconstruction -- Special System Topologies -- Putting MPI to Use: Applications.
- MEMS and nanotechnology-based sensors and devices for communications, medical and aerospace applications2008 CRCnetBASEA.R. Jha.
- 2015 ScienceDirectedited by Yaoliang Tang, Buddhadeb Dawn.Insights into the Mechanism of Exosome Formation and Secretion / Kobina Essandoh, Guo-Chang Fan -- An Overview of the Proteomic and miRNA Cargo in MSC-Derived Exosomes / Soon Sim Tan, Tian Sheng Chen, Kok Hian Tan, Sai Kiang Lim -- Exosome Function in miRNA-Mediated Paracrine Effects / Sathyamoorthy Balasubramanian, Sheeja Rajasingh, Jayakumar Thangavel, Buddhadeb Dawn, Johnson Rajasingh -- Current Methods to Purify and Characterize Exosomes / W. Michael Dismuke, Yutao Liu -- Stem Cell Extracellular Vesicles: A Novel Cell-Based Therapy for Cardiovascular Diseases / Ewa K. Zuba-Surma, Marta Adamiak, Buddhadeb Dawn -- Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles in Cardioprotection and Myocardium Repair / Bin Yu, Muhammad Ashraf, Meifeng Xu -- Engineered/Hypoxia-Preconditioned MSC-Derived Exosome: Its Potential Therapeutic Applications / Wei Zhu, Han Chen, Jian'an Wang -- Exosome-Based Translational Nanomedicine: The Therapeutic Potential for Drug Delivery / Lei Lv, Qingtan Zeng, Shenjun Wu, Hui Xie, Jiaquan Chen, Xiang Jiang Guo, Changning Hao, Xue Zhang, Meng Ye, Lan Zhang -- Effect of Exosomes from Mesenchymal Stem Cells on Angiogenesis / Susmita Sahoo, Feng Dong, Lola DiVincenzo, William Chilian, Liya Yin -- Exosomes for Bone Diseases / Paulomi Sanghavi, Porter Young, Sunil Upadhyay, Mark W. Hamrick -- Diagnostic and Prognostic Applications of MicroRNA-Abundant Circulating Exosomes / Baron Arnone, Xiaoqi Zhao, Zhipeng Zou, Gangjian Qin, Min Cheng.
- 2008 ScienceDirectedited by Bhanu P. Jena.Also available: Print – 2008
- 2012 CRCnetBASEedited by Jaime Castillo-León, Winnie Edith Svendsen, Maria Dimaki.Interfacing biological material with micro- and nanodevices / Jaime Castillo-León and Winnie E. Svendsen -- Atomic force microscopy for liquid applications / Zachary James Davis -- Manipulation by electrical fields / Maria Dimaki -- Optical manipulation techniques / Kirstine Berg-Sørensen -- Ultrasonic manipulation techniques / Stefano Oberti and Jürg Dual -- 3D biomanipulation using microgrippers / Peter Bøggild -- Magnetic manipulation of biological structures / Maria Dimaki and Winnie E. Svendsen -- Microfluidic manipulation of biological samples / Fridolin Okkels.
- 2013 Wileyedited by Murugan Ramalingam, Esmaiel Jabbari, Seeram Ramakrishna, and Ali Khadembosseini.Stem cells and nanotechnology in tissue engineering and regenerative medicine / Rocky Tuan -- Nanofiber technology for controlling stem cell functions and tissue engineering / Seeram Ramakrishna, Shayanti Mukherjee -- Micro- and nanoengineering approaches to developing gradient biomaterials suitable for interface tissue engineering / Ali Khademhosseini, Serge Ostrovidov -- Microengineered polymer and ceramic-based biomaterial scaffolds : a topical review on design, processing, and biocompatibility properties / Bikramjit Basu, Garima Tripathi -- Synthetic enroutes to engineer electrospun scaffolds for stem cells and tissue regeneration / Seeram Ramakrishna, Radhakrishnan Sridhar -- Integrating top-down and bottom-up scaffolding tissue engineering approach for bone regeneration / Esmaiel Jabbari, Yunzhi Yang -- Characterization of the adhesive interactions between cells and biomaterials / John Fisher -- Microfluidic formation of cell-laden hydrogel modules for tissue engineering / Shoji Takeuchi, Yuya Morimoto -- Micro- and nanospheres for tissue engineering / John Jansen -- Micro and nano technologies to engineer bone regeneration / Balaji Sitharaman -- Micro and nanotechnology for vascular tissue engineering / Laura Suggs -- Application of stem cells in ischemic heart disease / Gangapatnam Subrahmanyam, Ravi Shankar.
- Microfabricated magnetic sifter and high throughput physical fabrication of magnetic nanoparticles for applications in protein and cell separation2010Christopher Michael Earhart.Nanoscience and nanotechnology have been applied in recent years to cancer research, with the goal of bringing about a revolutionary change in the ways in which cancer is diagnosed and treated. Magnetic nanotechnologies, in particular, have shown significant potential in several areas, such as imaging, therapeutics, early detection, and point-of-care therapy monitoring. Most applications of magnetic nanotechnology in cancer research involve the use of nanoscale magnetic carriers. Depending on the properties of the particular carrier and the manner in which they are employed, magnetic carriers can act as MRI contrast enhancing agents, drug delivery vehicles, bio-labels for detection with magnetic biosensors, or selection agents in immunomagnetic separation platforms. The small sizes (10-100 nm), functional surface chemistries, and controllable magnetic responses of nanoscale magnetic carriers allows for interaction with and control of biological entities in both novel and powerful ways. The focus of this thesis is on a specific application of magnetic carriers -- magnetic separation of biomolecules and rare cells. After an introduction and an overview of magnetic separation principles are given in Chapters 1 and 2, Chapters 3-6 discuss the design, fabrication, and use of a novel magnetic separation device, the magnetic sifter. The magnetic sifter is a microfabricated, 7 x 7 mm planar die containing a dense array of pores (~200-5000/mm^2) in a magnetically soft membrane. When magnetized by an external field, the sifter pores generate large magnetic field gradients (~10^6 T/m) near the pore edges, which can capture nanoscale magnetic carriers with high efficiency and throughput. The gradients can be turned off by removing the external field, and the magnetic carriers can be released. The magnetic sifter is a microfluidic device, in the sense that it contains microfabricated, micron-scale pores which generate large field gradients. It is also a macrofluidic device, in that high volume throughput is achieved by parallel flow through the dense array of pores. Magnetic modeling of the magnetic sifter and a method for its fabrication are presented in Chapters 3 and 4. When paired with magnetic carriers functionalized with recognition moieties, the magnetic sifter can be used in both protein and cell enrichment schemes. The focus of Chapter 5 is on using the magnetic sifter to capture individual magnetic nanoparticles. The intended application is for enrichment of cancer protein markers prior to detection with a magnetic spin-valve biosensor. High capture efficiencies (80-100%) of magnetic nanoparticles have been achieved for a single pass through the magnetic sifter. Magnetic nanoparticles can also be released from the magnetic sifter with nearly 100% efficiency. The focus of Chapter 6 is the use of the magnetic sifter for rare cell enrichment, for applications in enumeration and enrichment of circulating tumor cells. It is shown that the magnetic sifter can capture tumor cells from whole blood with high efficiency and throughput (~60% at 5 ml/hr). Furthermore, with its planar structure and presentation of captured cells, the magnetic sifter doubles as a cell imaging platform, allowing for identification and quantification with optical microscopy. In addition to its high capture efficiency and gentle release of captured cells, the small size and scalable fabrication of the magnetic sifter are attractive for applications in point-of-care cancer diagnostics for early detection and monitoring of metastatic disease. In Chapter 7, a method for high-throughput fabrication of novel magnetic carriers, synthetic antiferromagnetic (SAF) nanoparticles is presented. The method has enabled production of large quantities of SAF nanoparticles, which have desirable properties for applications in magnetic separation. The capture and release behavior of SAF nanoparticles with the magnetic sifter has been demonstrated. High capture efficiencies are achieved at flow rates 10-20x higher than what was previously possible with commercially available magnetic carriers. Both the magnetic sifter and physically fabricated SAF nanoparticles offer unique advantages over traditional technologies. They are each, in their own right, promising new technologies for applications in cancer detection and therapy monitoring.
- 2011Sarah Paige Sherlock.In recent years there has been a growing interest in utilizing nanomaterials for drug delivery and biomedical imaging applications. This work focuses on the development of two multifunctional graphitic-carbon based nanomaterials capable of acting as both drug delivery agents and as contrast agents for either magnetic resonance imaging or near-infrared fluorescence imaging. Both of these agents heat under near-infrared light and are capable of loading chemotherapy drugs making them multifunctional in nature. The first material discussed is a FeCo-graphitic carbon nanocrystal loaded with doxorubicin. Addition of near-infrared photothermal therapy significantly increases the cellular toxicity of these nanocrystals in vitro. Treatment of breast cancer tumors in mice using combined nanocrystal drug delivery and photothermal therapy resulted in complete tumor regression in 45% of mice. The imaging capability of these nanocrystals is demonstrated through high-resolution magnetic resonance imaging of microvessels in rabbits. The potential long-term biodistribution and safety of this material is evaluated. The second graphitic-carbon nanomaterial used in this work is single-walled carbon nanotubes. This material is developed as a deep-tissue fluorescent imaging agent due to their inherit photoluminescence beyond 1 micron. This light emission is demonstrated to be particularly useful for in vivo imaging by minimizing light scattering by tissues leading to crisp anatomical resolution.
- 2012 SpringerEran Zahavy ... [et al.], editors.Biomolecule/nanomaterial hybrid systems for nanobiotechnology -- Superresolution optical fluctuation imaging (SOFI) -- Application of nanoparticles for the detection and sorting of pathogenic bacteria by flow-cytometry -- Advancing nanostructured porous si-based optical transducers for label free bacteria detection -- Gold fibers as a platform for biosensing -- Surface-enhanced raman spectroscopy of organic molecules adsorbed on metallic nanoparticles -- Quantum dots and fluorescent protein FRET-based biosensors -- Semiconductor quantum dots as FRET acceptors for multiplexed diagnostics and molecular ruler application -- Assembly and microscopic characterization of DNA origami structures -- DNA nanotechnology -- Role of carbohydrate receptors in the macrophage uptake of dextran-coated iron oxide nanoparticles -- Toxicity of gold nanoparticles on somatic and reproductive cells -- Ultrasound activated nano-encapsulated targeted drug delivery and tumour cell poration -- Ultrasound mediated localized drug delivery -- Sonochemical proteinaceous microspheres for wound healing -- Alendronate liposomes for antitumor therapy: activation of [gamma] [delta] T cells and inhibition of tumor growth.Also available: Print – 2012
- 2011Kosar Baghbani Parizi.Biosensors are used for detecting biological molecules such as proteins and nucleic acids. Traditional techniques, such as Enzyme-linked Immuno-sorbent Assay (ELISA) are sensitive but require several hours to yield results and usually require attaching a fluorophore molecule to the target molecule. The creation of label-free, fast, more accurate and integrated detection devices is imperative and we are increasingly looking to the nano-world for such technology. Micro-machined biosensors that employ electrical detection are now being developed. Impedance biosensor is a class of electrical biosensors that shows promise for point-of-care and other applications due to low cost, ease of miniaturization and label-free operation. Critically important component of any bio-detection system is the core biosensor device. Here we have designed, developed, tested and optimized a nano-biosensor that is configured and fabricated using silicon process technology. Electrical nano-sensors rely on label free detection of biochemical reactions in real time. These electrical sensors can measure impedance change as an electrical 'signature' of the nucleic acid or proteins interactions via a number of different mechanisms that are determined by their specific design and geometry. These nano-sensor designs will lead to an improvement in sensitivity by increasing the signal to noise ratio which results in more accurate readings through a reduction of spurious signal generation. We have developed a nano-bridge biosensor with a depletion-mode silicon 'nano-resistor' for the detection of DNA and protein at very low concentrations. In order to achieve higher sensitivity the sensing surface area is significantly increased as well as doping profile of impurities in silicon nano-resistor is optimized.. In contrast to a conventional Si enhancement mode MOSFET, this device behaves similar to depletion mode MOSFET, thereby it is always in the "ON" state, and no threshold voltage is needed to turn it into the active sensing mode. In addition signal calibration is not required due to a linear I-Vg characteristic at low Vg. The nano-bridge design has been optimized for maximal [Delta]I/I. The linearity of the response shows that the design will allow measurement of charge induced changes over a wide range with no threshold and high signal to noise ratios. To increase sensing throughput we will flow the solution containing the target molecules over an array of such sensing structures each of which has its own integrated readout circuitry that will offer 'real-time' detection (i.e. several minutes) of un-labeled molecules without sacrificing sensitivity. These electrical nano-biosensors are much more suited for the development of affordable bio-detection platforms, because they do not require expensive labeling reagents, rely on fabrication processes well established in the semiconductor IC industry, do not need bulky, expensive optical readout systems, and more importantly, can generate data on real time. One of the most important issues in the design of these sensor devices is to achieve high signal to noise ratio in order to make them amenable to sensitive detection of biological events, molecular interactions or chemical reactions. In order to improve the sensitivity and signal to noise ratio and to address the need for high density array construction we have designed and partially tested a nano-scale sensor with spatial structure, type and signal detection principles. The nano-bridge sensor is a double-gated depletion-mode semiconductor nano-resistive sensor. The structure and fabrication of these sensors will lead to improved sensitivity and greater accuracy of DNA hybridization detection up to 10 fM.
- 2010 CRCnetBASEeditors, Kamilla Lein Kjølberg, Fern Wickson."This book explores the enormous diversity in social perspectives on the emergence of nanoscale sciences and technologies. It points to four nodes of interest where nano meets macro: in the making, in the public eye, in the big questions, and in the tough decisions. Each node draws attention to important lines of research and pertinent issues. The book is designed for interdisciplinary teaching, but the richness of issues and perspectives makes it of interest to all researchers, practitioners, and non-academics wanting an introduction to social perspectives on nanoscale sciences and technologies."
- v. 2, 2007 Wileyedited by Christof M. Niemeyer and Chad A. Mirkin.[v. 1]. Concepts, applications, and perspectives -- 1 . Biocompatible inorganic devices / Thomas Sawitowski -- 2. Microfluidics meets nano : lab-on-a-chip devices and their potential for nanobiotechnology / Holger Bartos, Friedrich Götz, and Ralf-Peter Peters -- 3. Microcontact printing of proteins / Emmanuel Delamarche -- 4. Cell-nanostructure interactions / Joachim P. Spatz -- 5. Defined networks of neuronal cells in vitro / Andreas Offenhäusser and Angela K. Vogt -- 6. S-Layers / Uwe B. Sleytr ... [et al.] -- 7. Engineered nanopores / Hagan Bayley ... [et al.] -- 8. Genetic approaches to programmed assembly / Stanley Brown -- 9. Microbial nanoparticle production / Murali Sastry ... [et al.] -- 10. Magnetosomes : nanoscale magnetic iron minerals in bacteria / Richard B. Frankel and Dennis A. Bazylinski -- 11. Bacteriorhodopsin and its potential in technical applications / Norbert Hampp and Dieter Oesterhelt -- 12. Polymer Nanocontainers / Alexandra Graff ... [et al.] -- 13. Biomolecular motors operating in engineered environments / Stefan Diez, Jonne H. Helenius, and Jonathon Howard -- 14. Nanoparticle-biomaterial hybrid systems for bioelectronic devices and circuitry / Eugenii Katz and Itamar Willner -- 15. DNA-protein nanostructures / Christof M. Neimeyer -- 16. DNA-templated electronics / Erez Braun and Uri Sivan -- 17. Biomimetic fabrication of DNA-based metallic nanowires and networks / Michael Mertig and Wolfgang Pompe -- 18. Mineralization in nanostructured biocompartments : biomimetic ferritins for high-density data storage / Eric L. Mayes and Stephen Mann -- 19. DNA-gold nanoparticle conjugates / C. Shad Thaxton and Chad A. Mirkin -- 20. DNA nanostructures for mechanics and computing : nonlinear thinking with life's central molecule / Nadrian C. Seeman -- 21. Nanoparticles as non-viral transfection agents / M.N.V. Ravi Kumar, Udo Bakowsky, and Claus-Michael Lehr -- 22. Luminescent quantum dots for biological labeling / Xiaohu Gao and Shuming Nie -- 23. Nanoparticle molecular labels / James F. Hainfeld, Richard D. Powell, and Gerhard W. Hacker -- 24. Surface biology : analysis of biomolecular structure by atomic force microscopy and molecular pulling / Emin Oroudjev, Signe Danielsen and Helen G. Hansma -- 25. Force spectroscopy / Markus Seitz -- 26. Biofunctionalized nanoparticles for surface-enhanced raman scattering and surface plasmon resonance / Mahnaz El-Kouedi and Christine D. Keating -- 27. Bioconjugated silica nanoparticles for bioanalytical applications / Timothy J. Drake, Xiaojun Julia Zhao, and Weihong Tan. -- v. 2. More concepts and applications -- Part I. Self-Assembly and Nanoparticles: Novel Principles -- ch. 1. Self-Assembled Artificial Transmembrane Ion Channels / Mary S. Gin, Emily G. Schmidt and Pinaki Talukdar, p. 1-15 -- ch. 2. Self-Assembling Nanostructures from Coiled-Coil Peptides / Maxim G. Ryadnov and Derek N. Woolfson, p. 17-38 -- ch. 3. Synthesis and Assembly of Nanoparticles and Nanostructures Using Bio-Derived Templates / Erik Dujardin and Stephen Mann, p. 39-63 -- ch. 4. Proteins and Nanoparticles: Covalent and Noncovalent Conjugates / Rochelle R. Arvizo, Mrinmoy De and Vincent M. Rotello, p. 65-78 -- ch. 5. Self-Assembling DNA Nanostructures for Patterned Molecular Assembly / Thomas H. LaBean, Kurt V. Gothelf and John H. Reif, p. 79-97 -- ch. 6. Biocatalytic Growth of Nanoparticles for Sensors and Circuitry / Ronan Baron, Bilha Willner and Itamar Willner, p. 99-121 -- Part II. Nanostructures for Analytics -- ch. 7. Nanoparticles for Electrochemical Bioassays / Joseph Wang, p. 123-140 -- ch. 8. Luminescent Semiconductor Quantum Dots in Biology / Thomas Pons, Aaron R. Clapp, Igor L. Medintz and Hedi Mattoussi, p. 141-157 -- ch. 9. Nanoscale Localized Surface Plasmon Resonance Biosensors / Katherine A. Willets, W. Paige Hall, Leif J. Sherry, Xiaoyu Zhang, Jing Zhao and Richard P. Van Duyne, p. 159-173 -- ch. 10. Cantilever Array Sensors for Bioanalysis and Diagnostics / Hans Peter Lang, Martin Hegner and Christoph Gerber, p. 175-195 -- ch. 11. Shear-Force-Controlled Scanning Ion Conductance Microscopy / Tilman E. Schäffer, Boris Anczykowski, Matthias Böcker and Harald Fuchs, p. 197-212 -- ch. 12. Label-Free Nanowire and Nanotube Biomolecular Sensors for In-Vitro Diagnosis of Cancer and other Diseases / James R. Heath, p. 213-232 -- ch. 13. Bionanoarrays / Rafael A. Vega, Khalid Salaita, Joseph J. Kakkassery and Chad A. Mirkin, p. 233-259 -- Part III. Nanostructures for Medicinal Applications --. ch. 14. Biological Barriers to Nanocarrier-Mediated Delivery of Therapeutic and Imaging Agents, p. 261-284 / Rudy Juliano -- ch. 15. Organic Nanoparticles: Adapting Emerging Techniques from the Electronics Industry for the Generation of Shape-Specific, Functionalized Carriers for Applications in Nanomedicine / Larken E. Euliss, Julie A. DuPont and Joseph M. DeSimone, p. 285-303 -- ch. 16. Poly(amidoamine Dendrimer-Based Multifunctional Nanoparticles / Thommey P. Thomas, Rameshwer Shukla, Istvan J. Majoros, Andrzej Myc and James R. Baker, p. 305-319 -- ch. 17. Nanoparticle Contrast Agents for Molecular Magnetic Resonance Imaging / Young-Wook Jun, Jae-Hyun Lee and Jinwoo Cheon, p. 321-346 -- ch. 18. Micro- and Nanoscale Control of Cellular Environment for Tissue Engineering / Ali Khademhosseini, Yibo Ling, Jeffrey M. Karp and Robert Langer, p. 347-364 -- ch. 19. Diagnostic and Therapeutic Targeted Perfluorocarbon Nanoparticles / Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza and Samuel A. Wickline, p. 365-380 -- Part IV. Nanomotors -- ch. 20. Biological Nanomotors / Manfred Schliwa, p. 381-399 -- ch. 21. Biologically Inspired Hybrid Nanodevices / David Wendell, Eric Dy, Jordan Patti and Carlo D. Montemagno, p. 401-418.
- 2013 Springer Protocolsedited by Sandra J. Rosenthal and David W. Wright.High-aspect-ratio gold nanorods : their synthesis and application to image cell-induced strain fields in collagen films / Davin J. Chernak ... [et al.] -- Imaging intracellular quantum dots : fluorescence microscopy and transmission electron microscopy / Craig J. Szymanski ... [et al.] -- Imaging of cell populations in atherosclerosis using quantum dot nanocrystals / Joshua R. Trantum and Ashwath Jayagopal -- Imaging of endothelial progenitor cell subpopulations in angiogenesis using quantum dot nanocrystals / Joshua M. Barnett, John S. Penn, and Ashwath Jayagopal -- Imaging single synaptic vesicles in mammalian central synapses with quantum dots / Qi Zhang -- Quantum dot-based single-molecule microscopy for the study of protein dynamics / Jerry C. Chang and Sandra J. Rosenthal -- Three-dimensional molecular imaging with photothermal optical coherence tomography / Melissa C. Skala ... [et al.] -- Detecting respiratory syncytial virus using nanoparticle-amplified immuno-PCR / Jonas W. Perez ... [et al.] -- Gold nanoparticle-oligonucleotide conjugates for the profiling of malignant melanoma phenotypes / John W. Stone ... [et al.] -- Methods for isolating RNA sequences capable of binding to or mediating the formation of inorganic materials / Carly Jo Carter, Alina Owczarek, and Daniel L. Feldheim -- Single-walled carbon nanotube-mediated small interfering RNA delivery for gastrin-releasing peptide receptor silencing in human neuroblastoma / Jingbo Qiao ... [et al.] -- Amino acid mediated linear assembly of au nanomaterials / Manish Sethi and Marc R. Knecht -- Enzyme-gold nanoparticle bioconjugates : quantification of particle stoichiometry and enzyme specific activity / Jacqueline D. Keighron and Christine D. Keating -- In vivo testing for gold nanoparticle toxicity / Carrie A. Simpson, Brian J. Huffman, and David E. Cliffel -- Methods for studying toxicity of silica-based nanomaterials to Living Cells / Yang Zhao ... [et al.].
- 2006 Springeredited by M. Reza Mozafari.Also available: Print – 2006
- 2014 CRCnetBASEedited by Bhanu P. Jena and Douglas J. Taatjes.Porosomes--the universal secretory portals in cells: a brief essay / Bhanu P. Jena -- The hair cell porosome: molecular and synaptic implications / Dennis G. Drescher -- The neuronal porosome complex in mammalian brain: a study using electron microscopy / Mzia G. Zhvania, Nadezhda J. Japaridze, Mariam G. Qsovreli, Vera G. Okuneva, Arkadi G. Surmava, and Tamar G. Lordkipanidze -- Granule size distribution suggests mechanism: the case for granule growth and elimination as a fusion nano-machine / Ilan Hammel and Isaac Meilijson -- Probing protein assembly, biomineralization, and biomolecular interactions by atomic force microscopy / Kang Rae Cho and James J. De Yoreo -- High-resolution imaging of amylin aggregation and internalization in pancreatic cells: implications in health and disease / Saurabh Trikha, Sanghamitra Singh, and Aleksandar M. Jeremic -- Repair of Nanodefects in a two-dimensional crystal anticoagulant shield in the antiphospholipid syndrome: novel molecular strategies assessed by atomic force microscopy / Douglas J. Taatjes, Anthony S. Quinn, Xiao-Xuan Wu, Han-Mou Tsai, and Jacob H. Rand -- A novel approach to study molecular evolution: detection of ancestral conformation hidden in present-day proteins using antibody as nanostructure probes / Jian-Ping Jin -- mRNA nanomachines and stress reprogramming following brain ischemia / Donald J. DeGracia, Jill T. Jamison, Manupreet Chawla, Monique K. Lewis, Michelle Smith, and Jeffery J. Szymanski -- Physical properties and biomedical applications of superparamagnetic iron oxide nanoparticles / Gavin Lawes, Ratna Naik, and Prem Vaishnava -- Atomic force microscopy imaging of DNA delivery nanosystems / Yi Zou, David Oupicky, and Guangzhao Mao -- Impedance spectroscopy for characterization of biological function / Brian C. Riggs, Janet L. Paluh, G.E. Plopper, and Douglas B. Chrisey.
- Nanofunctional materials, nanostructures and nanodevices for cancer applications : November 28-December 3, 2011, Boston, Massachusetts, USA2012 Cambridgeeditors, S. Svenson, P. Grodzinski, S. Manalis, X-J. Liang, W. Lin.Synthesis of Gold Nanoparticles Coated with pH-Responsive Polymers and Evaluation of the Cellular Uptake. -- Demonstration of biocompatibility of single walled carbon nanotubes with blood leukocytes. -- "Design of Poly(ethylene glycol)-Polycaprolactone Diblock Micelles with RGD Targeting Ligands and Embedded Iron Oxide Nanoparticles for Thermally-activated Release". -- Stable Colloids of Paclitaxel Nanoparticles Coated with PEGylated Polyelectrolyte Shells. -- Composite nanosilver structures suitable for plasmonic biosensors. -- Microemulsion Synthesis of Iron Core/Iron Oxide Shell Magnetic Nanoparticles and Their Physicochemical Properties. -- Near Infrared Tunable Gold Nanoparticles for Low Power Laser Ablation of Esophageal Adenocarcinoma. -- Rapid Diagnosis of E. Coli using Carbon Nanotube Field Effect Transistor Direct Binding Assay. -- Biocompatible Hybrid Plasmonic-Magnetic Nanoparticles for Bioimaging. -- Cytotoxic and Anti-cancer Effects of Nickel Nanowires against Pancreatic Cancer Cells. -- Breast Adenocarcinoma Cell Functions on Nanopatterned PLGA Surfaces. -- Surface Engineered Porous Silicon-based Nanostructures for Cancer Therapy.
- 2013 Springer Protocolsedited by Alioscka A. Sousa, Michael J. Kruhlak.Introduction : nanoimaging techniques in biology / Alioscka A. Sousa and Michael J. Kruhlak -- Live-cell imaging of vesicle trafficking and divalent metal ions by total internal reflection fluorescence (TIRF) microscopy / Merewyn K. Loder, Takashi Tsuboi, and Guy A. Rutter -- 4Pi microscopy / Roman Schmidt, Johann Engelhardt, and Marion Lang -- Fluorescence in situ hybridization applications for super-resolution 3D structured illumination microscopy / Yolanda Markaki [and others] -- Two-color STED imaging of synapses in living brain slices / Jan Tonnesen and U. Valentin Nagerl -- Super-resolution imaging by localization microscopy / Dylan M. Owen [and others] -- High-content super-resolution imaging of live cell by uPAINT / Gregory Giannone [and others] -- Super-resolution fluorescence imaging with blink microscopy / Christian Steinhauer, Michelle S. Itano, and Philip Tinnefeld -- Photoswitchable fluorophores for single-molecule localization microscopy / Kieran Finan, Benjamin Flottmann, and Mike Heilemann -- Single-molecule tracking of mRNA in living cells / Mai Yamagishi, Yoshitaka Shirasaki, and Takashi Funatsu -- Semiautomatic, high-throughput, high-resolution protocol for three-dimensional reconstruction of single particles in electron microscopy / Carlos Oscar Sorzano [and others] -- Mass mapping of amyloid fibrils in the electron microscope using STEM imaging / Alioscka A. Sousa and Richard D. Leapman -- Elemental mapping by electron energy loss spectroscopy in biology / Maria A. Aronova and Richard D. Leapman -- Cellular nanoimaging by cryo electron tomography / Roman I. Koning and Abraham J. Koster -- Large-volume reconstruction of brain tissue from high-resolution serial section images acquired by SEM-based scanning transmission electron microscopy / Masaaki Kuwajima, John M. Mendenhall, and Kristen M. Harris -- 3D imaging of cells and tissues by focused ion beam/ scanning electron microscopy (FIB/SEM) / Damjana Drobne -- Preparation of gold nanocluster bioconjugates for electron microscopy / Christine L. Heinecke and Christopher J. Ackerson -- Atomic force microscopy imaging of macromolecular complexes / Sergio Santos, Daniel Billingsley, and Neil Thomson -- Imaging of transmembrane proteins directly incorporated within supported lipid bilayers using atomic force microscopy / Daniel Levy and Pierre-Emmanuel Milhiet -- Functional AFM imaging of cellular membranes using functionalized tips / Lilia A. Chtcheglova and Peter Hinterdorfer -- Near-field scanning optical microscopy for high-resolution membrane studies / Heath A. Huckabay [and others] -- Correlative fluorescence and EFTEM imaging of the organized components of the mammalian nucleus / Michael J. Kruhlak -- High data output method for 3-D correlative light-electron microscopy using ultrathin cryosections / Katia Cortese [and others] -- Correlative optical and scanning probe microscopies for mapping interactions at membranes / Christopher M. Yip -- Nanoimaging cells using soft x-ray tomography / Dilworth Y. Parkinson [and others] -- Secondary ion mass spectrometry imaging of biological membranes at high spatial resolution / Haley A. Klitzing, Peter K. Weber, and Mary L. Kraft.
- 2014 SpringerDavid G. Capco, Yongsheng Chen, editors.Presence in, and release of, nanomaterials from consumer products / Yu Yang and Paul Westerhoff -- Nanoparticle aggregation: principles and modeling / Wen Zhang -- Influences of nanomaterials on the barrier function of epithelial cells / Shariq Ali and Erik Rytting -- Engineered nanoparticles induced brush border disruption in a human model of the intestinal epithelium / James J. Faust, Benjamin M. Masserano, Adam H. Mielke, Anup Abraham, and David G. Capco -- Nanoparticles: cellular uptake and cytotoxicity / Isaac M. Adjei, Blanka Sharma and Vinod Labhasetwar -- Atomic force microscopy study of the interaction of DNA and nanoparticles / Kungang LI, Songyan Du, Steven Van Ginkel, and Yongsheng Chen -- Intracellular signal modulation by nanomaterials / Salik Hussain, Stavros Garantziotis, Fernando Rodrigues-Lima, Jean-Marie Dupret, Armelle Baeza-Squiban, Sonja Boland -- Nanomaterials: impacts on cells and cell organelles / Željka Krpetić, Sergio Anguissola, David Garry, Philip Kelly and Kenneth A. Dawson -- Design, synthesis, and functionalization of nanoparticles for therapeutic drug delivery / Taraka Sai Pavan Grandhi and Kaushal Rege -- Preparation of nanoscale pulmonary drug delivery formulations by spray drying / Adam Bohr, Christian A. Ruge, and Moritz Beck-Broichsitter -- Nanomedicine: the promise and challenges in cancer chemotherapy / Youssef W. Naguib and Zhengrong Cui -- Transgenerational effects of NMs / Anna Poma, Sabrina Colafarina, Gabriella Fontecchio, and Giuseppe Chichiricco -- Stem cells and nanomaterials / Maria-Claude Hofmann.Also available: Print – 2014
- 2013 Springer Protocolsedited by Paolo Bergese, Kimberly Hamad-Schifferli.Preparation of 2 nm gold nanoparticles for in vitro and in vivo applications / Daniel F. Moyano, Bradley Duncan, and Vincent M. Rotello -- DNA conjugation to nanoparticles / Sunho Park -- Conjugation of nanoparticles to proteins / Marie-Eve Aubin-Tam -- Water-solubilization and functionalization of semiconductor quantum dots / Christina M. Tyrakowski, Adela Isovic, and Preston T. Snee -- Synthesizing and modifying peptides for chemoselective ligation and assembly into quantum dot-peptide bioconjugates / W. Russ Algar ... [et al.] -- Reliable methods for silica coating of au nanoparticles / Isabel Pastoriza-Santos and Luis M. Liz-Marzán -- Surface modifications by polymers for biomolecule conjugation / Laura Sola ... [et al.] -- Functionalization protocols of silicon micro/nano- mechanical biosensors / Francesca Frascella and Carlo Ricciardi -- Stability and aggregation assays of nanoparticles in biological media / James Chen Yong Kah -- Electrochemical measurements of DNA melting on surfaces / Irina Belozerova, Dongbiao Ge, and Rastislav Levicky -- Formation and characterization of the nanoparticle-protein corona / Marco P. Monopoli ... [et al.] -- Electrophoretic implementation of the solution-depletion method for measuring protein adsorption, adsorption kinetics, and adsorption competition among multiple proteins in solution / Hyeran Noh ... [et al.] -- Hyperspectral microscopy for characterization of gold nanoparticles in biological media and cells for toxicity assessment / Christin Grabinski, John Schlager, and Saber Hussain -- Immunocytochemistry, electron tomography, and energy dispersive x-ray spectroscopy (EDXS) on cryosections of human cancer cells doped with stimuli responsive polymeric nanogels loaded with iron oxide nanoparticles / Roberto Marotta ... [et al.] -- Zwitterion siloxane to passivate silica against nonspecific protein adsorption / Zaki G. Estephan and Joseph B. Schlenoff -- Preparation and characterization of DNA block copolymer assemblies loaded with nanoparticles / Xi-Jun Chen, Robert J. Hickey, and So-Jung Park -- Polyaspartic acid coated iron oxide nanoprobes for PET/MRI imaging / Taku Cowger and Jin Xie -- Ligand synthesis and passivation for silver and large gold nanoparticles for single-particle-based sensing and spectroscopy / Daniel Montiel ... [et al.] -- Noncovalent intracellular drug delivery of hydrophobic drugs on au NPs / Tennyson Doane and Clemens Burda -- Modification of carbon nanotubes for gene delivery vectors / Victor Ramos-Perez ... [et al.] -- Lipid-based nanoparticles as nonviral gene delivery vectors / Daniele Pezzoli ... [et al.] -- Stabilizing gold nanoparticle bioconjugates in physiological conditions by PEGylation / Joan Comenge and Víctor F. Puntes.
- 2007 Springeredited by M. Resa Mozafari.Micro and nano systems in biomedicine and drug delivery / Nesrin Hasirci -- Newlipid- and glycolipid-based nanosystems for targeted gene delivery: cholenims, glycoclips, and chitosan / R.I. Zhdanov ... [et. al] -- Artificial implants - new developments and associated problems / Abdelwahab Omri -- Niosomes as nanocarrier systems / Nefise Ozlen Sahin -- Starch - a potential biomaterial for biomedical application / Lovedeep Kaur, Jaspreet Singh, Qiang Liu -- Alternative applications for drug delivery: nasal and pulmonary routes / A. Yekta Ozer -- An overview of lipsome-derived nanocarrier technologies / M. Reza Mozafari, Kianoush Khosravi-Darani -- Uptake studies of free and liposomal sclareol by MCF-7 and H-460 human cancer cell lines / Agnes Paradissi ... [et. al] -- Release advantages of a liposomal dendrimer- doxorubicin complex, over conventional liposomal formulation of doxorubicin / Aristarchos Papagiannoros, Costas Demetzos -- Applications of light and electron microscopic techniques in liposome research / A. Yekta Ozer.
- 2013 Wileyedited by Ashutosh Tiwari and Atul Tiwari.Part I: Biomedical nanomaterials -- Nanoemulsions : preparation, stability and application in biosciences / Thomas Delmas, Nicolas Atrux-Tallau, Mathieu Goutayer [and others] -- Multifunctional polymeric nanostructures for therapy and diagnosis / Angel Contreras-García, Emilio Bucio -- Carbon nanotubes : nanotoxicity testing and bioapplications / R. Sharma, S. Kwon -- Part II: Advanced nanomedicine -- Discrete metalla-assemblies as drug delivery vectors / Bruno Therrien -- Nanomaterials for management of lung disorders and drug delivery / Jyothi U. Menon, Aniket Wadajkar, Zhiwei Xie [and others] -- Nano-sized calcium phosphate (CaP) carriers for non-viral gene/drug delivery / Donghyun Lee, Geunseon Ahn, Prashant N. Kumta -- Part III: Nanotheragnostics -- Organics modified mesoporous silica for controlled drug delivery systems / Jingke Fu, Yang Zhao, Yingchun Zhu [and others] -- Responsive polymer-inorganic hybrid nanogels for optical sensing, imaging, and drug delivery / Weitai Wu, Shuiquin Zhou -- Core/shell nanoparticles for drug delivery and diagnosis / Hwanbum Lee, Jae Yeon Kim, Eun Hee Lee [and others] -- Dendrimer nanoparticles and their applications in biomedicine / Arghya Paul, Wei Shao, Tom J. Burdon [and others] -- Theranostic nanoparticles for cancer imaging and therapy / Mami Murakami, Mark J. Ernsting [and others] -- Part IV: Nanoscaffolds technology -- Nanostructure polymers in function generating substitute and organ transplants / S.K. Shulka -- Electrospun nanofiber for three dimensional cell culture / Yashpal Sharma, Ashutosh Tiwari, Hisatoshi Kobayashi [and others] -- Magnetic nanoparticles in tissue regeneration / Anuj Tripathi, Jose Savio Melo, Stanislaus Francis D'Souza -- Core-sheath fibers for regenerative medecine / Rajesh Vasita, Fabrizio Gelain.
- 2015 CRCnetBASEedited by Dipanjan Pan.Chapter 1. Introduction -- chapter 2. Nuclear imaging with nanoparticles / Ali Azhdarinia and Sukhen C. Ghosh -- chapter 3. Molecular imaging at nanoscale with magnetic resonance imaging / Patrick M. Winter -- chapter 4. Optical imaging with nanoparticles / Walter J. Akers -- chapter 5. Contrast agents for computed tomographic imaging / Dipanjan Pan, Santosh K. Misra, and Sumin Kim -- chapter 6. Nanomedicine : perspective and promises / Dipanjan Pan.
- 2009 CRCnetBASEedited by Mingjun Zhang, Ning Xi.This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory. It will advance knowledge of nanoscale science and engineering by efficiently employing quantitative tools for fundamental biomedical engineering and biological science research. The book starts by introducing the concept of nanomedicine, and provides basic mathematical modeling techniques that can be used to model nanoscale biomedical and biological systems. It then demonstrates how this id.
- 2011 Kargervolume editor, Christoph Alexiou.Speakers at the symposium -- Nanoscale drug delivery/drug design -- Nanotoxicity -- Diagnostics and imaging -- Therapeutic applications -- Antibody therapies.
- 2012 CRCnetBASEeditors, Rajaventhan Srirajaskanthan, Victor R. Preedy.Nanomedicine-based use of sirna in cancer / Guillermo N. Armaiz-Pena ... [et al.] -- Nanocarriers for gene delivery / Conchita Tros de Ilarduya and Gloria Gonzalez-Aseguinolaza -- Cancer cell photothermolysis and gold nanorod surface plasmons / Cheng-Lung Chen and Yang-Yuan Chen -- Tocotrienol loaded lipid nanoparticles in cancer / Sami Nazzal and Paul W. Sylvester -- Utilization of magnetic nanoparticles for cancer therapy / Deryl L. Troyer and Stefan H. Bossmann -- Nanoparticle probes and molecular imaging in cancer / Dongfang Liu and Ning Gu -- Iron and ethylcellulose nanoplatforms for cancer targeting / José L. Arias, Margarita López-Viota, and Ma Adolfina Ruiz -- Matrix scaffolds in cancer cell biology, physiological representation and nanoscale characterisation / Hsin-ya Chien ... [et al.] -- Fluorescence nanoprobe imaging tumor by sensing the acidic microenvironment / Lu Wang and Cong Li -- Magnetic nanorings and nanotubes for cancer detection and therapy / Hai Ming Fan and Malini Olivo -- Silicon nanowire arrays and other silicon nanostructures and their clinical applications to cancer / Murugan Veerapandian and Min-Ho Lee -- Silver nanomedicine and cancer / ... [et al.] -- Nanobubbles and their putative application to cancer medicine / Tianyi M. Krupka and Agata A. Exner -- Nano-strategies in the delivery of antitumor drugs to cancer / José L. Arias -- Gene silencing with sirna encapsulated nanoparticles to overcome tumor multidrug resistance / Mansoor M. Amiji, Francis Hornicek, and Zhenfeng Duan -- Nano-flow liquid chromatography mass spectrometric analysis of glycans in cancer / S. Hunter Walker and David C. Muddiman -- Composite nano-sensor arrays technology in lung cancer / Silvano Dragonieri, Giorgio Pennazza, and Marco Santonico -- Nano arsenic oxide (As2o3)/(Fe2o3) iron oxide complexes for liver cancer / Ziyu Wang and Dongsheng Zhang -- Hepatocellular carcinoma and midkine-antisense oligonucleotide-loaded nanoparticles / Licheng Dai, Yaoxing and Zhongjing -- Nanotechnology and nanostructures applied to head and neck cancer / Erik C. Dreaden, Mostafa A. El-Sayed, and Ivan H. El-Sayed.
- 2012 CRCnetBASEedited by Mathew Sebastian, Neethu Ninan, and A.K. Haghi.1. Ethosomes as non-invasive loom for transdermal drug delivery system / Sudhakar C.K. ... [et al.] -- 2. Colloidal delivery systems for phytochemicals / Ashok R. Patel -- 3. Polymer-modified gene delivery vectors retargeted with recombinant proteins / R. Pola ... [et al.] -- 4. Study of drug transport properties of acrylic based iron (III) oxide filled IPN / S. Goswami ... [et al.] -- 5. Poly(amido-amine)s as carriers for intracellular delivery of drugs and proteins / Fabio Fenili ... [et al.] -- 6. Nanoparticles as adjuvant(s) for mucosal vaccine delivery / P.N. Gupta ... [et al.] -- 7. Biosynthesis of silver nanoparticles, characterization and their antimicrobial activity / K. Mallikarjuna ... [et al.] -- 8. Gold-peptide nanoparticles activation of macrophages / Jagat R. Kanwar, Ganesh Mahidhara, and Rupinder K. Kanwar -- 9. Combating infectious diseases : nanotechnology-based drug delivery / Zahoor Ahmad and Rajesh Panday -- 10. Dendrimers in biology and medicine / Dzmitry Shcharbin ... [et al.] -- 11. Capsules based on lipid vesicles : potentiality for drug delivery / Brigitte Pépin-Donat ... [et al.] -- 12. A simulation study on the transport of ions through ion channels / Keka Talukdar and Apurba Krishna Mitra -- 13. Effects of intranasal administration of interferon-alpha on rat behavior / Loginova N.A. ... [et al.] -- 14. Neurotransplantation of neural and mesenchymal stem cells for correction of posthypoxic disorders / Loseva E.V. ... [et al.] -- 15. Spray drying in pharmaceutical manufacturing an overview / Prathima Srinivas -- 16. RNA nanotechnology in nanomedicine / Wade W. Grabow ... [et al.].
- 2012 CRCnetBASEeditors, Ross J. Hunter, Victor R. Preedy."The nanosciences are a rapidly expanding field of research with applicability to all areas of health and disease prevention, including cardiology in its broadest sense. This book covers a variety of nano subjects and areas as applied to the heart and circulatory system. There are state-of-the-art chapters on nanoparticles, nanowires, nanoscale topography, nanosensors, nanospheres, nanospin probes, nanomatrices and nanobubbles to name but a few topics. Their applications to cardiovascular disorders and their treatments are also described"--Provided by publisher.
- Nanomedicine. Cancer, diabetes, and cardiovascular, central nervous system, pulmonary and inflammatory diseases. 1st ed.2012 ScienceDirectedited by Nejat Düzgüneş.
- 2013 Wileyedited by Ajay Kumar Mishra.Nanomedicine -- High-technology therapy using biomolecules or synthetic compounds for hiv inhibition -- Emerging nanomedicine approaches for osteochondral tissue regeneration -- Synthesis of poly(methacrylate) encapsulated magnetite nanoparticles via phosphonic acid anchoring chemistry and its applications toward biomedicine -- Potentiometric PVC membrane sensors and their analytical applications in pharmaceuticals and environmental samples at micro- and nano-level -- Bioceramics: silica-based organic-inorganic hybrid materials for medical applications -- Recent advances of multifunctional nanomedicines -- Nanomedicinal approaches for diabetes management -- Polymeric nanofibers in regenerative medicine -- Drug delivery and therapeutics -- Multifunctional nano/micro polymer capsules as potential drug delivery and imaging agents -- Nanophosphors-nanogold immunoconjugates in isolation of biomembranes and in drug delivery -- Cyclodextrin-based nanoengineered drug delivery system -- Medicinal patches and drug nanoencapsulation: a noninvasive alternative -- Dendrimers: a class of polymer in the nanotechnology for drug delivery -- Designing nanocarriers for drug delivery -- Multifunctional polymeric micelles for drug delivery and therapeutics -- Nanoparticles-based carriers for gene therapy and drug delivery.
- 2013 CRCnetBASEedited by Arun Kumar, Heidi M. Mansour, Adam Friedman, and Eric R. Blough.Nanoparticles in drug delivery systems / Emilio Castro and Arun Kumar -- Synthesis and characterization of nanoencapsulated drugs / Arun Kumar, Ashley E. Saienni, and Niketa Dixit -- Nanoparticles for pulmonary drug delivery / Heidi M. Mansour, Chun-Woong Park, and Don Hayes -- Biological systems for the delivery of nanoparticles / Niketa Dixit ... [et al.] -- Nanodermatology : giant role of nanotechnology in diagnosis and treatment of skin disease / Adam Friedman -- Nanoparticles for drug delivery of small molecules / Ana Sofia Macedo and Eliana B. Souto -- Nanoparticle therapies for wounds and ulcer healing / Chiara Gardin ... [et al.] -- Nanoparticles in bioimaging / Javier L. Pou Ucha -- Nanoparticles in anticancer drug delivery / Frederic Lagarce -- Formulations of nanoparticles in drug delivery / Sushama Talegaonkar -- Nanoparticles for ocular drug delivery / Jaleh Barar -- Toxicology of nanoparticles / Eric R. Blough -- Animal and cellular models for use in nanoparticles safety study / Kevin M. Rice and Eric R. Blough.
- 2011 CRCnetBASEeditors, Ross J. Hunter, Victor R. Preedy.Nanomedicine : an introduction / Lajos P. Balogh -- The regulation of nanomedicine / Joel D'Silva and Diana Bowman -- Nanotubes and their application to nanomedicine / Gianni Ciofani -- Nanoparticles for topical application / Kerriann R. Greenhalgh -- Nanocrystal formulations for improved delivery / Jan Möschwitzer and Rainer H. Müller -- Antioxidant nanoparticles / Beverly A. Rzigalinski ... [et al.] -- Lipid nanocapsules in nanomedicine / Marie Morille ... [et al.] -- Nanotheragnostic colloids in disease / José L. Arias -- Nanotechnology in controlling infectious disease / Rehab Amin -- Virus-based nanoparticles as tools for biomedicine / Stefan Franzen, Steven A. Lommel, and Bruce Oberhardt -- Safety of nanoparticles in medicine / Maria Dusinska ... [et al.] -- Pulmonary drug delivery with nanoparticles / Moritz Beck-Broichsitter ... [et al.] -- Carbon nanotubes in infectious diseases / Yitzhak Rosen ... [et al.] -- Radiation protection with nanoparticles / Cheryl H. Baker -- Nanoparticle therapy in arthritis / José L. Arias -- Phospholipid-based nanomicelles in cancer nanomedicine / Hayat Onyuksel and Amrita Banerjee -- Tumor-specific liposomal nanomedicines : antitumor antibody-modified doxorubicin-loaded liposomes / Tamer Elbayoumi and Vladimir Torchilin -- Nanomedicine in blood diseases / Denis B. Buxton -- Nanomedicine and neurodegenerative disorders / Ari Nowacek ... [et al.] -- Nanotechnological applications in tissue and implant / Viswanathan S. Saji and Han-Cheol Choe.
- Nanomedicine. Infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology, and gene medicine. 1st ed.2012 ScienceDirectedited by Nejat Düzgüneş.Enhanced antiviral activity of acyclovir loaded into nanoparticles / Roberta Cavalli ... [et al.] -- Gold manno-glyconanoparticles for intervening in HIV gp120 carbohydrate-mediated processes/ Paolo Di Gianvincenzo ... [et al.] -- Nanoparticle-mediated targeted delivery of antiretrovirals to the brain / Supriya D. Mahajan ... [et al.] -- Antibacterial activity of doxycycline-loaded nanoparticles / Ranjita Misra and Sanjeeb K. Sahoo -- Antimicrobial properties of electrically formed elastomeric polyurethane-copper oxide nanocomposites for medical and dental applications / Z. Ahmad ... [et al.] -- Gastrointestinal delivery of anti-inflammatory nanoparticles / Hamed Laroui, Shanthi V. Sitaraman, and Didier Merlin -- Chitosan-based nanoparticles as a hepatitis B antigen delivery system / Filipa Lebre ... [et al.] -- Targeting nanoparticles to dendritic cells for immunotherapy / Luis J. Cruz ... [et al.] -- Protein-carbon nanotube sensors : single platform integrated micro clinical lab for monitoring blood analytes / Sowmya Viswanathan ... [et al.] -- Investigating the toxic effects of iron oxide nanoparticles / Stefaan J. Soenen ... [et al.] -- Cytotoxicity of gold nanoparticles / Yu Pan, Matthias Bartneck, and Willi Jahnen-Dechent -- Design of target-seeking antifibrotic compounds / Tero A.H. Järvinen -- Design and fabrication of N-alkyl-polyethylenimine-stabilized iron oxide nanoclusters for gene delivery / Gang Liu ... [et al.] -- Cell-penetrating peptide-based systems for nucleic acid delivery : a biological and biophysical approach / Sara Trabulo ... [et al.] -- Multifunctional envelope-type nano device (MEND) for organelle targeting via a stepwise membrane fusion process / Yuma Yamada, Hidetaka Akita, and Hideyoshi Harashima -- Lipopolyplexes as nanomedicines for therapeutic gene delivery / Leire García ... [et al.] -- Interfering nanoparticles for silencing microRNAs / Huricha Baigude and Tariq M. Rana -- Genetic nanomedicine : gene delivery by targeted lipoplexes / Nejat Nejat Düzgüneş and Conchita Tros de Ilarduya.
- 2009 ScienceDirectedited by Hari S. Sharma.
- 2014 ScienceDirectDiana Boraschi and Albert Duschl.Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage.
- 2012 Springer Protocolsedited by Mikhail Soloviev.Procedures for the synthesis and capping of metal nanoparticles / Claudia Gutierrez-Wing, J. Jesus Velazquez-Salazar, and Miguel Jose-Yacaman -- Preparation of concentrated colloids of gold core-silica shell nanoparticles for biomedical applications / Yeon-Su Park -- Biosynthesis of silver and gold nanoparticles using Bacillus licheniformis / Muthu Irulappan Sriram, Kalimuthu Kalishwaralal, and Sangiliyandi Gurunathan -- Gold nanoparticle antibody conjugates for use in competitive lateral flow assays / Julian Bailes [and others] -- Gold nanoparticles for immunogold localization of antigens in plant tissues / Sadaki Yokota -- RNA quantification using noble metal nanoprobes : simultaneous identification of several different mRNA targets using color multiplexing and application to cancer diagnostics / Joao Conde [and others] -- Effect of gold nanoparticle conjugation on the activity and stability of functional proteins / Julian Bailes [and others] -- Synthesis of semiconductor nanoparticles / Xianfeng Chen and Peter J. Dobson -- Size-selective synthesis of ultrasmall hydrophilic CdSe nanoparticles in aqueous solution at room temperature / Yeon-Su Park [and others] -- Synthesis and functionalization of CdSe/ZnS QDs using the successive ion layer adsorption reaction and mercaptopropionic acid phase transfer methods / Ana Sofia Miguel, Christopher Maycock, and Abel Oliva -- In vivo, site-specific, covalent conjugation of quantum dots to proteins via split-intein splicing / Anna Charalambous [and others] -- Evaluating the potential of quantum dots for in vitro biological studies : effects on gene expression using microarray analysis / Babu R. Prasad [and others] -- Use of quantum dots for immunochemistry applications / Helena Monton [and others] -- Quantum Dots for Labeling Live Cells / Yun Chen -- Labeling and imaging mesenchymal stem cells with quantum dots / Maria C. Collins [and others] -- Application of semiconductor quantum dots for enhancing peptide desorption, improving peak resolution and sensitivity of detection in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry / Julian Bailes and Mikhail Soloviev -- Near-infrared fluorescence labeling of iron nanoparticles and applications for cell labeling and in vivo imaging / Jinke Wang [and others] -- Labeling stem cells with superparamagnetic iron oxide nanoparticles : analysis of the labeling efficacy by microscopy and magnetic resonance imaging / Jasmin, Ana Luiza Machado Torres [and others] -- Noninvasive quantification of magnetic nanoparticles by means of magnetorelaxometry / Maik Liebl and Dietmar Eberbeck -- Synthesis, application, and tracking of magnetic carbon-coated nanoparticles in plants / Alejandro Perez-de-Luque [and others] -- Synthesis of biocompatible gelatinated thioglycolic acid-capped CdTe quantum dots ("jelly dots") / Valerie A. Gerard [and others] -- Preparation and characterization of biomimetic nanoparticles for drug delivery / Ana Maria Carmona-Ribeiro -- Preparation of nanoparticles by spray-drying and their use for efficient pulmonary drug delivery / Hao-Ying Li and Fan Zhang -- Synthesis and evaluation of airway targeted PLGA nanoparticles for drug delivery in obstructive lung diseases / Neeraj Vij -- Preparation of siRNA-encapsulated PLGA aanoparticles for sustained release of siRNA and evaluation of encapsulation efficiency / Panayotis Pantazis [and others] -- Synthesis of poly (2-hydroxyethyl methacrylate) (PHEMA) based nanoparticles for biomedical and pharmaceutical applications / Rajesh Saini, Jaya Bajpai, and Anil K. Bajpai -- Preparation of lipid : peptide : DNA (LPD) nanoparticles and their use for gene transfection / Fan Zhang and Hao-Ying Li -- Crotamine : a novel cell-penetrating polypeptide nanocarrier with potential anti-cancer and biotechnological applications / Mirian A.F. Hayashi [and others] -- Elastin-based nanoparticles for delivery of bone morphogenetic proteins / Raul Machado [and others] -- Synthesis, surface modification, characterization, and biomedical in vitro applications of organically modified silica (ORMOSIL) nanoparticles / Diksha and Indrajit Roy -- Extraction of organic nanoparticles from plants / Scott C. Lenaghan [and others] -- Assessment of cytotoxicity of carbon nanoparticles using 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)- 2-(4-sulfophenyl)-2h-tetrazolium (MTS) cell viability assay / Amanda M. Schrand, Jonathan B. Lin, and Saber M. Hussain -- Luciferase reporter system for studying the effect of nanoparticles on gene expression / Min Ding, Linda Bowman, and Vincent Castranova -- Single cell gel electrophoresis assay (comet assay) for evaluating nanoparticles-induced DNA damage in cells / Linda Bowman, Vincent Castranova, and Min Ding -- Assessment of toxicity of nanoparticles using insects as biological models / Yan Zhou [and others] -- Evaluation of cytotoxicity of 3-mercaptopropionic acid-modified quantum dots on Medicago sativa cells and tissues / Ana Raquel Santos [and others] -- Scanning transmission electron microscopy methods for the analysis of nanoparticles / Arturo Ponce, Sergio Mejia-Rosales, and Miguel Jose-Yacaman -- Total internal reflection fluorescence (TIRF) microscopy for real-time imaging of nanoparticle-cell plasma membrane interaction / Ladan Parhamifar and S. Moein Moghimi -- Microscopy imaging methods for the detection of silver and titanium nanoparticles within cells / Robert Martin Zucker and Kaitlin Marie Daniel -- Detection of TiO2 nanoparticles in cells by flow cytometry / Robert Martin Zucker and Kaitlin Marie Daniel -- Nanoparticle tracking analysis for the multiparameter characterization and counting of nanoparticle suspensions / Matthew Wright -- Relevance of two-dimensional brownian motion dynamics in applying nanoparticle tracking analysis / Paul Van der Meeren, Marios Kasinos, and Hans Saveyn -- Nanoparticle bridges for studying electrical properties of organic molecules / Klaus Leifer [and others].
- 2010 SpringerJan C.M. Marijnissen, Leon Gradoń, editors.
- 2008 CRCnetBASEAntonietta M. Gatti, Stefano Montanari.Describes the impact of nanoparticles and microparticles on human and animal health and offers criteria for preventing potential problems deriving from these particles.
- 2011Chong Xie.Abstract: The small scale of nano-materials makes them one of the best man-made candidates to interact with biological systems at subcellular or even molecular level. It has been the focal point of the research interests to interfacing live cells with one dimensional nanostructures, such as nanowires and nanopillars. In my Phd research, I have utilized nanopillar based structures and devices to interface biological cells electrically, optically and mechanically. 1. We achieve improved electric interface between biological cells and solid state device by using arrays of vertically aligned nanopillar electrodes. Their tight attachment to the cell membrane allows us to acquire intracellular-like action potential signals non-destructively from cultured cardiomyocytes, which is responsible for various important cellular functions. 2. We demonstrate below-the-diffraction-limit observation volume in vitro and inside live cells by using vertically aligned silicon dioxide nanopillars. With a diameter much smaller than the wavelength of visible light, a transparent silicon dioxide nanopillar embedded in a nontransparent substrate restricts the propagation of light and affords evanescence wave excitation along its vertical surface. This effect creates highly-confined illumination volume that selectively excites fluorescence molecules in the vicinity of the nanopillar. We show that this nanopillar illumination can be used for in vitro single molecule detection with high fluorescence background. In addition, we demonstrate that vertical nanopillars interface tightly with live cells and function as highly localized light sources inside the cell. Furthermore, chemical modification of the nanopillar surface provides a unique way to locally recruit proteins of interest and simultaneously observe their behavior within the complex, crowded environment of the cell. 3. We engineer and fabricate vertically nanopillar arrays, and culture various types of cells atop. We study the cell growth pattern in presence of nanopillar arrays, including attachment, migration, etc. We also design patterned nanopillar arrays and utilized them to guide and control cell growth via cell-nanopillar interaction.
- 2012 Springer Protocolsedited by Maria E. Gracheva.Detecting and characterizing individual molecules with single nanopores -- Protein sensing with engineered protein nanopores -- Measurements of DNA immobilized in the alpha-hemolysin nanopore -- DNA unzipping and protein unfolding using nanopores -- DNA characterization with ion beam-sculpted silicon nitride nanopores -- DNA sequencing by nanopore-induced photon emission -- Optical tweezers for mechanical control over DNA in a nanopore -- Analyzing single DNA molecules by nanopore translocation -- DNA characterization by transverse electrical current in a nanochannel -- Optimization of the molecular dynamics method for simulations of DNA and ion transport through biological nanopores -- Polymer translocation through an electrically tunable nanopore in a multilayered semiconductor membrane -- Graphene nanopore devices for DNA sensing -- Measuring single-wall carbon nanotubes with solid-state nanopores -- Passive and electrically actuated solid-state nanopores for sensing and manipulating DNA.
- 2011 Springer Protocolsedited by Steven A. Toms, Robert J. Weil.MALDI-TOF serum profiling using semiautomated serum peptide capture with magnetic reversed phase (C18) beads / Jaco C. Knol and Connie R. Jimenez -- Proteomics of epithelial lining fluid obtained by bronchoscopic microprobe sampling / Lorenza Franciosi [and others] -- Protein identification using nano-HPLC-MS : ESI-MS and MALDI-MS interfaces / Rui Vitorino [and others] -- Three-dimensional peptide fractionation for highly sensitive nanoscale LC-based shotgun proteomic analysis of complex protein mixtures / Sricharan Bandhakavi [and others] -- Nanospray ion mobility mass spectrometry of selected high mass species / Iain Campuzano and Kevin Giles -- Nanoelectrospray-MSn of native and permethylated glycans / Christina Bleckmann, Hildegard Geyer, and Rudolf Geyer -- N-linked global glycan profiling by nanoLC mass spectrometry / Michael S. Bereman and David C. Muddiman -- Applications of nanoscale liquid chromatography coupled to tandem mass spectrometry in quantitative studies of protein expression protein-protein interaction, and protein phosphorylation / Metodi V. Metodiev -- Nano LC-MS/MS : a robust setup for proteomic analysis / Marco Gaspari and Giovanni Cuda -- Nanofluidic devices for rapid continuous-flow bioseparation / Pan Mao and Jianping Fu -- Quantifying attomole amounts of proteins from complex samples by nano-LC and selected reaction monitoring / Thomas Frohlich and Georg J. Arnold -- Sample preparation method for gold nanoparticle-assisted laser desorption/ionization time-of-flight mass spectrometry / Yen-Hsiu Lin and Wei-Lung Tseng -- Nanostructured TiO2 thin films for phosphoproteomics studies with MALDI mass spectrometry / Federico Torta [and others] -- Nanofilament silicon for matrix-free laser desorption/ionization mass spectrometry / Chia-Wen Tsao and Don L. DeVoe -- Protein nanoarrays for high-resolution patterning of bacteria on gold surfaces / Cait Costello [and others] -- Engineered multifunctional nanotools for biological applications / Mohammed Ibrahim Shukoor [and others] -- Selective capture of phosphopeptides by zirconium phosphonate-magnetic nanoparticles / Liang Zhao, Renan Wu, and Hanfa Zou -- Nanowire biosensors for label-free, real-time, ultrasensitive protein detection / Gengfeng Zheng and Charles M. Lieber -- Generation of anti-infectome/anti-proteome nanobodies / Gholamreza Hassanzadeh-Ghassabeh, Dirk Saerens, and Serge Muyldermans -- Isolation, propagation, and analysis of biological nanoparticles / Michael P. Linnes [and others] -- Functionalized soluble nanopolymers for phosphoproteome analysis / Anton Iliuk [and others] -- Elucidating structural dynamics of integral membrane proteins on native cell surface by hydroxyl radical footprinting and nano LC-MS/MS / Yi Zhu, Tiannan Guo, and Siu Kwan Sze -- Application of electrostatic repulsion hydrophilic interaction chromatography to the characterization of proteome, glycoproteome, and phosphoproteome using nano LC-MS/MS / Piliang Hao, Huoming Zhang, and Siu Kwan Sze.
- 2011 Springer Protocolsedited by Ping Wang.Nanoscale-engineered cytochrome P450 system with a branch structure / Hidehiko Hirakawa and Teruyuki Nagamune -- Chemically induced self-assembly of enzyme nanorings / Brian R. White, Qing Li, and Carston R. Wagner -- Self-assemblies of polymer-enzyme conjugates at oil-water interfaces for interfacial biocatalysis / Guangyu Zhu and Ping Wang -- Molecular assembly-assisted biocatalytic reactions in ionic liquids / Muhammad Moniruzzaman and Masahiro Goto -- Organic-soluble enzyme nano-complexes formed by ion-pairing with surfactants / Songtao Wu, Andreas Buthe, and Ping Wang -- Enzyme-immobilized CNT network probe for in vivo neurotransmitter detection / Gi-Ja Lee [and others] -- Kinesin I ATPase manipulates biohybrids formed from tubulin and carbon nanotubes / Cerasela Zoica Dinu [and others] -- Reversible his-tagged enzyme immobilization on functionalized carbon nanotubes as nanoscale biocatalyst / Liang Wang and Rongrong Jiang -- TiO2 nanoparticle system for sacrificial solar H2 production prepared by rational combination of a hydrogenase with a ruthenium photosensitizer / Erwin Reisner and Fraser A. Armstrong -- Preparation and characterization of single-enzyme nanogels / Jun Ge [and others] -- Fabrication and characterization of bioactive thiol-silicate nanoparticles / Frances Neville and Paul Millneri -- Immobilization of enzymes on fumed silica nanoparticles for applications in nonaqueous media / Juan C. Cruz [and others] -- Microencapsulation of bioactive nanoparticles / Fei Gao, Ping Wang, and Guanghui Ma -- Engineering the logical properties of a genetic and gate / Daniel J. Sayut, Yan Niu, and Lianhong Sun -- Strain engineering strategies for improving whole-cell biocatalysis : engineering Escherichia coli to overproduce xylitol as an example / Jonathan W. Chin and Patrick C. Cirino -- Enzyme-carrying electrospun nanofibers / Hongfei Jia -- Uniform lab-scale biocatalytic nanoporous latex coatings for reactive microorganisms / Jimmy L. Gosse and Michael C. Flickinger -- Entrapment of enzymes in nanoporous sol-gels / Andreas Buthe.
- 2014 Springer Protocolsedited by U. Valentin Nägerl, Interdisciplinary Insitute for Neuroscience, CNRS/University of Bordeaux, Bordeaux, France, Antoine Triller, Insitute of Biology, Ecole Normal Supérieure/INSERM/CNRS, Paris, France.
- 2009 Springer[edited by] Donglu Shi.Stem Cells and Nanostructured Materials / Vince Beachley and Xuejun Wen -- Biomedical Polymer Nanofibers for Emerging Technology / Kwideok Park, Won Ho Park, Jun Sik Son and Dong Keun Han -- Nanoscale Mechanisms for Assembly of Biomaterials / Zhijie Sui and William L. Murphy -- Fabrication and Assembly of Nanomaterials and Nanostructures for Biological Detections / Qingkai Yu and Jie Lian -- Nanostructured Materials Constructed from Polypeptides / Peng Jing, Jangwook P. Jung and Joel H. Collier -- Photoluminescent Carbon Nanomaterials: Properties and Potential Applications / Yaping Sun, Fushen Lu, Xin Wang, Li Cao and Yi Lin, et al. -- Microwave-assisted Synthesis and Processing of Biomaterials / Yingjie Zhu and Jiang Chang -- Characterizing Biointerfaces and Biosurfaces in Biomaterials Design / Kalpana S. Katti, Devendra Verma and Dinesh R. Katti -- Carbon Nanotubes for Electrochemical and Electronic Biosensing Applications / Ningyi Liu, Qing Zhang, Mary B Chan-Park, Changming Li and Peng Chen -- Heparin-Conjugated Nanointerfaces for Biomedical Applications / Ki Dong Park, Yoon Ki Joung, Jin Woo Bae and Dong Hyun Go -- Inorganic Nanoparticles for Biomedical Applications / Mei Chee Tan, Gan Moog Chow, Lei Ren and Qiqing Zhang -- Nano Metal Particles for Biomedical Applications / Kyung A. Kang, Bin Hong and Hanzhu Jin -- Micro- and Nanoscale Technologies in High-Throughput Biomedical Experimentation / Vikramaditya G. Yadav, Mark D. Brigham, Ling Yibo, Christopher Rivest and Utkan Demirci, et al. -- Delivery System of Bioactive Molecules for Regenerative Medicine / Gilson Khang, Yoon Sun Jung, Soon Hee Kim, Moon Suk Kim and Hai Bang Lee -- Modification of Nano-sized Materials for Drug Delivery / Tao Xu, Heather L. Nichols, Ning Zhang and Xuejun Wen -- Polymeric Nano Micelles as a Drug Carrier / Moon Suk Kim, Hyun Hoon, Gilson Khang and Hai Bang Lee -- DNA Nanotechnology / Junping Zhang and Roger J. Narayan -- Nanoscale Bioactive Surfaces and Endosseous Implantology / Yunzhi Yang, Yongxing Liu, Sangwon Park, Hyunseung Kim and Kwangmin Lee, et al. -- Carbon Nanotube Smart Materials for Biology and Medicine / Yeo Heung Yun, Vesselin N. Shanov, Adam Bange, William R. Heineman and H. Brian Halsall, et al. -- Microscopic Modeling of Phonon Modes in Semiconductor Nanocrystals / Wei Cheng, Shangfen Ren and David T. Marx -- Fracture Processes in Advanced Nanocrystalline and Nanocomposite Materials / I. A. Ovid'ko -- Synthesis, Properties and Application of Conducting PPY Nanoparticles / Xingui Li, Meirong Huang and Yunbin Xie -- Field Emission of Carbon Nanotubes / Baoqing Zeng and Zhifeng Ren -- Flexible Dye-Sensitized Nano-Porous Films Solar Cells / Dongshe Zhang, Tony Pereira, Torsten Oekermann, Katrin Wessels and Changyong Qin, et al. -- Magnetic Nanofluids: Synthesis and Structure / L. Vékás, M. V. Avdeev and Doina Bica.
- 2010 CRCnetBASEedited by Alberto Diaspro.STED microscopy with compact light sources / Lars Kastrup ... [et al.] -- Nonlinear fluorescence imaging by saturated excitation / Nicholas I. Smith ... [et al.] -- Far-field fluorescence microscopy of cellular structures at molecular optical resolution / Christoph Cremer ... [et al.] -- Fluorescence microscopy with extended depth of field / Kai Wicker and Rainer Heintzmann -- Single particle tracking / Kevin Braeckmans ... [et al.] -- Fluorescence correlation spectroscopy / Xianke Shi and Thorsten Wohland -- Two-photon excitation microscopy: a superb wizard for fluorescence imaging / Francesca Cella and Alberto Diaspro -- Photobleaching minimization in single- and multi-photon fluorescence imaging / Partha Pratim Mondal ... [et al.] -- Applications of second harmonic generation imaging microscopy / Paolo Bianchini and Alberto Diaspro -- Green fluorescent proteins as intracellular pH indicators / Fabio Beltram ... [et al.] -- Fluorescence photoactivation localization microscopy / Manasa V. Gudheti, Travis J. Gould, and Samuel T. Hess -- Molecular resolution of cellular biochemistry and physiology by FRET/FLIM / Fred S. Wouters and Gertrude Bunt -- FRET-based determination of protein complex structure at nanometer length scale in living cells / Valerică Raicu -- Automation in multidimensional fluorescence microscopy: novel instrumentation and applications in biomedical research / Mario Faretta -- Optical manipulation, photonic devices, and their use in microscopy / G. Cojoc ... [et al.] -- Optical tweezers microscopy: piconewton forces in cell and molecular biology / Francesco Difato ... [et al.] -- In vivo spectroscopic imaging of biological membranes and surface imaging for high-throughput screening / Jo L. Richens ... [et al.] -- Near-field optical microscopy: insight on the nanometer-scale organization of the cell membrane / Davide Normanno, Thomas van Zanten, and María F. García-Parajo.
- 2008 Springer Protocolsedited by Ehud Gazit, Ruth Nussinov.Molecular design of performance proteins with repetitive sequences, recombinant flagelliform spider silk as basis for biomaterials / Charlotte Vendrely, ... [et al.] -- Creation of hybrid nanorods from sequences of natural trimeric fibrous proteins by use of the fibritin trimerization motif / Katerina Papanikolopoulou, Mark J. van Raaij, Anna Mitraki -- Leucine zipper as a building block for self-assembled protein fibers / Maxim G Ryadnov, David Papapostolou, Derek N Woolfson -- Bioimimetic synthesis of bimorphic nanostructures / Joseph M. Slocik, Rajesh R. Naik -- Synthesis and primary characterization of self-assembled peptide-based hydrogels / Radhika P. Nagarkar and Joel P. Schneider -- Periodic assembly of nanospecies on repetitive DNA sequences generated on gold nanoparticles by rolling circle amplification / Weian Zhao, Michael A. Brook, Yingfu Li -- Protocols for the In Silico design of RNA nanostructures / Bruce A. Shapiro, ... [et al.] -- Self-assembly of fused homo-oligomers to create nanotubes / Idit Buch, ... [et al.] -- Computational methods in nanostructure design, replica exchange simulations of self-assembling peptides / Giovanni Bellesia, Sotiria Lampoudi, Joan-Emma Shea -- Modeling amyloid fibril formation / Maarten G. Wolf, Jeroen van Gestel, Simon W. de Leeuw -- Computer modeling in biotechnology / Aleksei Aksimentiev, ... [et al.] -- What can we learn from highly-connected 7-rich structures for structural interface design / Ugur Emekli, ... [et al.].
- 2012 CRCnetBASEYuri M. Yevdokimov, V.I. Salyanov, S.G. Skuridin."Written for chemists, physicists, molecular biologists, and students in related fields, this reference covers information presently available on the specific properties of metallic nanoparticles, and compares their properties with those related to nanoobjects formed by biological molecules. It also discloses details of formation and physic-chemical peculiarities of the DNA nanostructures and DNA-based nanoconstructions. Timely in publication, the reference contains more DNA physics and molecular biology than other published titles. Authors discuss how nucleic acid molecules and their complexes with chemical and biologically active compounds are of great interest in the development of various nanoscale systems and devices of practical importance"-- Provided by publisher.
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- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
- Red Book Online
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