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- Host-pathogen interactions methods and protocols 2008Springer Protocols
- Human and animal relationships. 2nd ed. 2008Springer
- IgE antibodies generation and function 2015SpringerBiology of IgE production: IgE cell differentiation and the memory of IgE responses / Jin-Shu He, Sriram Narayanan, Sharrada Subramaniam, Wen Qi Ho, Juan J. Lafaille and Maria A. Curotto de Lafaille -- Molecular mechanisms of IgE class switch recombination / Pei Tong and Duane R. Wesemann -- Anti-IgE therapy: clinical utility and mechanistic insights / Stephanie L. Logsdon and Hans C. Oettgen -- New insights on the signaling and function of the high-affinity receptor for IgE / Ryo Suzuki, Jörg Scheffel and Juan Rivera -- Helminth-induced IgE and protection against allergic disorders / Firdaus Hamid, Abena S. Amoah, Ronald van Ree and Maria Yazdanbakhsh -- IgE immunotherapy against cancer / Lai Sum Leoh, Tracy R. Daniels-Wells and Manuel L. Penichet -- Index.
- Immunology of infection. 3rd ed. 2010ScienceDirect1. The Immune Response to Infectious Agents / Stefan H.E. Kaufmann, Dieter Kabelitz -- 2. Immunomagnetic Isolation of Subcellular Compartments / Vladimir Tchikov, Jürgen Fritsch, Dieter Kabelitz, Stefan Schütze -- 3. Use of Bioinformatics to Predict MHC Ligands and T-Cell Epitopes: Application to Epitope-Driven Vaccine Design / Anne S. De Groot, Tobias Cohen, Matthew Ardito, Lenny Moise, Bill Martin, Jay A. Berzofsky -- 4. Genetics of Susceptibility and Resistance to Infection / Aurelie Cobat, Marianna Orlova, Alexandre Alcaїs, Erwin Schurr -- 5. Proteomic Approaches to Study Immunity in Infection / Gustavo A.de Souza, Harald G. Wiker -- 6. Isolation and Characterization of Human Epithelial Antimicrobial Peptides and Proteins / Jens.-M. Schröder -- 7. Visualization and Functional Evaluation of Phagocyte Extracellular Traps / Maren von Köckritz-Blickwede, Ohn Chow, Mariam Ghochani, Victor Nizet -- 8. Killer Cell Assays / Patricia Graef, Veit R. Buchholz, Dirk H. Busch -- 9. Analysis of Intestinal T Cell Populations and Cytokine Productions / Jun Kunisawa, Hiroshi Kiyono -- 10. Isolation and Measuring the Function of Professional Phagocytes: Murine Macrophages / Leanne Peiser, Subhankar Mukhopadhyay, Richard Haworth, Siamon Gordon -- 11. Measuring Immune Responses In Vivo / Stefan Ehlers, Norbert Reiling, Christoph Hölscher, Sahar Aly -- 12. Murine and Guinea Pig Models of Tuberculosis / Diane J. Ordway, lan M. Orme -- 13. The Leishmaniasis Model / Pascale Kropf, Ulrich D. Kadolsky, Matthew Rogers, Thomas E. Cloke, Ingrid Müller -- 14. Animal Models of Mucosal Candida Infections / Flavia De Bernardis, Silvia Arancia, Silvia Sandini -- 15. Mucosal Immunity and Inflammation / Ulrich Steinhoff, Alexander Visekruna -- 16. CD8 T-Cell Immunotherapy of Cytomegalovirus Disease in the Murine Model / Niels A.W. Lemmermann, Jürgen Podlech, Christof K. Seckert, Kai A. Kropp, Natascha K.A. Grzimek, Matthias J. Reddehase, Rafaela Holtappels -- 17. Measuring Immune Responses In Situ: Immunofluorescent and Immunoenzymatic Techniques / Antje Müller, Torsten Goldmann, Ulrike Seitzer -- 18. Measuring Human Cytokine Responses / Hans Yssel, John Wijdenes, René de Waal Malefyt, Jean-François Mathieu, Jérôme Pène -- 19. Human Dendritic Cell Subsets / Hideki Ueno, Eynav Klechevsky, A. Karolina Palucka, Jacques Banchereau.
- Immunology of the lymphatic system 2013SpringerImmunology of the Lymphatic System is a comprehensive study of the lymphatic system and its immunological role. It begins with lymphatic capillaries, their origin and development. It addresses lymph circulation, in general, with a special emphasis on lymph circulation in parenchymal organs. The next section focuses on lymph nodes, subcortical circulation and the conduit system. It discusses organs with no lymphatic system, such as the brain. Finally, it covers lymph composition and cells in the lymph. While primarily basic research, the volume touches upon elements of the clinical, as well, broadening its scope and appeal.
- In remembrance of Rudolf Virchow (1821-1902) / Schmidt, A. -- In memoriam of Rudolf Virchow: a historical retrospective including aspects of inflammation, infection and neoplasia / Schmidt, A., Weber, O.F. -- Aneuploidy and cancer: from correlation to causation / Duesberg, P. ... [et al.] -- Adult stem cell theory of the multi-stage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiated stem cells / Trosko, J.E., Tai, M.-H. -- Helicobacter pylori and gastric neoplasia / Leung, W.K. -- Schistosomiasis and neoplasia / Yosry, A. -- Relevant oncogenic viruses in veterinary medicine: original pathogens and animal models for human disease / Truyen, U., L"chelt, M. -- The inflammatory tumor microenvironment and its impact on cancer development / de Visser, K.E., Coussens, L.M. -- Co-opting macrophage traits in cancer progression: a consequence of tumor cell fusion? / Pawelek, J. ... [et al.] -- Carcinogenesis driven by bone marrow-derived stem cells / Dittmar, T. ... [et al.] -- Chemokine-directed metastasis / Gomperts, B.N., Strieter, R.M. -- Involvement of chemokine receptors in organ-specific metastasis / Zlotnik, A. -- Visualization of tumor cell extravasation / Heyder, C. ... [et al.] -- Options for visualizing metastatic disease in the living body / Helms, M.W., Brandt, B.H., Contag, C. -- Infection, inflammation and neoplasia: an interdisciplinary challenge / Zaenker, K.S.
- Infectious agents and cancer 2013SpringerThe Criteria of Inclusion of Infectious Agents in the List of Biological Carcinogens -- General Mechanisms of Biological Carcinogenesis -- The Role of Bacteria in Cancer Development -- The Role of Protozoa in Cancer Development -- The Role of Helminthes and Fungi in Cancer Development -- Organ Microbiota in Cancer Development: The Holy Grail of Biological Carcinogenesis -- Conclusions: Are We There Yet?
- Influenza pathogenesis and control Volume II / 2015SpringerPart I. Innate immunity. The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options / John R. Teijaro -- Innate immune sensing and response to influenza / Bali Pulendran and Mohan S. Maddur -- The NS1 protein: a multitasking virulence factor / Juan Ayllon and Adolfo García-Sastre -- Role of NK cells in influenza infection / Stacey Shultz-Cherry -- Host detection and the stealthy phenotype in influenza virus infection / Pradyot Dash and Paul G. Thomas -- Part II. Vaccines and adaptive immunity. Inactivated and adjuvanted influenza vaccines / Giuseppe Del Giudice and Rino Rappuoli -- Live attenuated influenza vaccine / Hong Jin and Kanta Subbarao -- Design of alternative live attenuated influenza virus vaccines / Courtney Finch, Weizhong Li and Daniel R. Perez -- Rapid production of synthetic influenza vaccines / Philip R. Dormitzer -- Influenza neuraminidase as a vaccine antigen / Maryna C. Eichelberger and Hongquan Wan -- Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin / Florian Krammer, Peter Palese and John Steel -- Structural characterization of viral epitopes recognized by broadly cross-reactive antibodies / Peter S. Lee and Ian A. Wilson -- Skin immunization with influenza vaccines / Ioanna Skountzou and Richard W. Compans -- Mucosal immunization and adjuvants / Hideki Hasegawa, Elly van Reit and Hiroshi Kida -- B cell responses to influenza infection and vaccination / Christopher Chiu, Ali H. Ellebedy, Jens Wrammert and Rafi Ahmed -- Memory CD4 T cells in influenza / Kyra D. Zens and Donna L. Farber -- The effector T cell response to influenza infection / Matthew M. Hufford, Taeg S. Kim, Jie Sun and Thomas J. Braciale -- Part III. New antiviral discovery. Antiviral effects of inhibiting host gene expression / Ralph A. Tripp and S. Mark Tompkins -- Index.
- Influenza pathogenesis and control. Volume I / 2014SpringerThis two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
- Antifungal agents -- Antifungal susceptibility testing: Clinical Laboratory and Standards Institute (CLSI) methods -- Antifungal susceptibility testing methods: non-CLSI methods for yeast and moulds -- Susceptibility testing of dermatophytes -- Usual susceptibility patterns of common yeasts -- Usual susceptibility patterns of common moulds and systemic fungi -- Usual susceptibility patterns for systemic dimorphic fungi -- Utility of antifungal susceptibility testing and clinical correlations.
- Interleukin-10 in health and disease 2014Springer" This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date."--Publisher's website.
- International handbook of foodborne pathogens 2003CRCnetBASE
- Intrinsic immunity 2013SpringerThe APOBEC3 Family of Retroelement Restriction Factors / Eric W. Refsland, Reuben S. Harris -- Inhibition of Retroviral Replication by Members of the TRIM Protein Family / Adam J. Fletcher, Greg J. Towers -- The Antiviral Activities of Tetherin / Stuart J. D. Neil -- Restriction of Retroviral Infection of Macrophages / Mark Sharkey -- Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors / Welkin E. Johnson -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants / György Szittya, József Burgyán -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates / Arabinda Nayak, Michel Tassetto, Mark Kunitomi, Raul Andino -- Roles of MicroRNAs in the Life Cycles of Mammalian Viruses / Eva Gottwein -- Interplay Between DNA Tumor Viruses and the Host DNA Damage Response / Karyn McFadden, Micah A. Luftig.
- Iron acquisition by the genus mycobacterium history, mechanisms, role of siderocalin, anti-tuberculosis drug development 2013SpringerIron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described. The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed. The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates.
- Jawetz, Melnick, & Adelberg's Medical microbiology 2013 (26th ed.)AccessMedicine
- Laboratory Protocols in Fungal Biology presents the latest techniques in fungal biology. This book analyzes information derived through real experiments, and focuses on cutting edge techniques in the field. The book comprises 57 chapters contributed from internationally recognised scientists and researchers. Experts in the field have provided up-to-date protocols covering a range of frequently used methods in fungal biology. Almost all important methods available in the area of fungal biology viz. taxonomic keys in fungi; histopathological and microscopy techniques; proteomics methods; genomics methods; industrial applications and related techniques; and bioinformatics tools in fungi are covered and complied in one book. Chapters include introductions to their respective topics, list of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting. Each chapter is self-contained and written in a style that enables the reader to progress from elementary concepts to advanced research techniques. Laboratory Protocols in Fungal Biology is a valuable tool for both beginner research workers and experienced professionals.
- Legionella pneumophila pathogenesis and immunity 2008Springer
- Leptospira and leptospirosis 2015SpringerThis volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world?s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis.
- Listeria, listeriosis, and food safety. 3rd ed. 2007CRCnetBASEThe genus Listeria and Listeria monocytogenes: phylogenetic position, taxonomy, and identification / Jocelyn Rocourt and Carmen Buchrieser -- Ecology of Listeria species and L. monocytogenes in the natural environment / Brian D. Sauders and Martin Wiedmann -- Listeriosis in animals / Irene V. Wesley -- Listeriosis in humans / John Painter and Laurence Slutsker -- Molecular virulence determinants of Listeria monocytogenes / Michael Kuhn and Werner Goebel -- Characteristics of Listeria monocytogenes important to food processors / Beatrice H. Lado and Ahmed E. Yousef -- Conventional methods to detect and isolate Listeria monocytogenes / Catherine W. Donnelly and David G. Nyachuba -- Rapid methods for detection of Listeria / Byron F. Brehm-Stecher and Eric A. Johnson -- Subtyping Listeria monocytogenes / Lewis M. Graves, Bala Swaminathan, and Susan B. Hunter -- Foodborne listeriosis / Dawn M. Norton and Christopher R. Braden -- Incidence and behavior of Listeria monocytogenes in unfermented dairy products / Elliot T. Ryser -- Incidence and behavior of Listeria monocytogenes in cheese and other fermented dairy products / Elliot T. Ryser -- Incidence and behavior of Listeria monocytogenes in meat products / Jeffrey M. Farber, Franco Pagotto, and Chris Scherf -- Incidence and behavior of Listeria monocytogenes in poultry and egg products / Elliot T. Ryser -- Incidence and behavior of Listeria monocytogenes in fish and seafood / Karen C. Jinneman, Marleen M. Wekell, and Mel W. Eklund -- Incidence and behavior of Listeria monocytogenes in products of plant origin / Robert E. Brackett -- Incidence and control of Listeria in food processing facilities / Jeffrey L. Kornacki and Joshua Gurtler -- Listeria: risk assessment, regulatory control, and economic impact / Ewen C.D. Todd -- Perspectives on research needs / Elmer H. Marth ... [et al.].
- Magnetoreception and magnetosomes in bacteria 2007Springer
- Management of antimicrobials in infectious diseases impact of antibiotic resistance. 2nd ed. 2010Springer
- V. 1: Introduction to the 11th Edition of the Manual of Clinical Microbiology -- Microscopy -- Laboratory Detection of Bacteremia and Fungemia -- Systems for Identification of Bacteria and Fungi -- Automation and Design of the Clinical Microbiology Laboratory -- Molecular Microbiology -- Immunoassays for Diagnosis of Infectious Diseases -- Prevention of Health Care-Associated Infections -- Investigation of Disease Outbreaks -- Molecular Epidemiology -- Procedures for the Storage of Microorganisms -- Prevention of Laboratory-Acquired Infections -- Decontamination, Disinfection, and Sterilization -- Biothreat Agents -- The Human Microbiome -- Microbial Genomics and Pathogen Discovery -- Taxonomy and Classification of Bacteria -- Specimen Collection, Transport, and Processing: Bacteriology -- Reagents, Stains, and Media: Bacteriology -- General Approaches to Identification of Aerobic Gram-Positive Cocci -- Staphylococcus, Micrococcus, and Other Catalase-Positive Cocci -- Streptococcus -- Enterococcus -- Aerococcus, Abiotrophia, and Other Aerobic Catalase-Negative, Gram-Positive Cocci -- General Approaches to the Identification of Aerobic Gram-Positive Rods -- Bacillus and Other Aerobic Endospore-Forming Bacteria -- Listeria and Erysipelothrix -- Coryneform Gram-Positive Rods -- Nocardia, Rhodococcus, Gordonia, Actinomadura, Streptomyces, and Other Aerobic Actinomycetes -- Mycobacterium: General Characteristics, Laboratory Detection, and Staining Procedures -- Mycobacterium: Laboratory Characteristics of Slowly Growing Mycobacteria -- Mycobacterium: Clinical and Laboratory Characteristics of Rapidly Growing Mycobacteria -- Approaches to the Identification of Aerobic Gram-Negative Bacteria -- Neisseria -- Aggregatibacter, Capnocytophaga, Eikenella, Kingella, Pasteurella, and Other Fastidious or Rarely Encountered Gram-Negative Rods -- Haemophilus -- Escherichia, Shigella, and Salmonella -- Klebsiella, Enterobacter, Citrobacter, Cronobacter, Serratia, Plesiomonas, and Other Enterobacteriaceae -- Yersinia -- Aeromonas -- Vibrio and Related Organisms -- Pseudomonas -- Burkholderia, Stenotrophomonas, Ralstonia, Cupriavidus, Pandoraea, Brevundimonas, Comamonas, Delftia, and Acidovorax -- Acinetobacter, Chryseobacterium, Moraxella, and Other Nonfermentative Gram-Negative Rods -- Bordetella and Related Genera -- Francisella -- Brucella -- Bartonella -- Legionella -- Approaches to Identification of Anaerobic Bacteria -- Peptostreptococcus, Finegoldia, Anaerococcus, Peptoniphilus, Veillonella, and Other Anaerobic Cocci -- Propionibacterium, Lactobacillus, Actinomyces, and Other Non-Spore-Forming Anaerobic Gram-Positive Rods -- Clostridium -- Bacteroides, Porphyromonas, Prevotella, Fusobacterium, and Other Anaerobic Gram-Negative Rods -- Algorithms for Identification of Curved and Spiral-Shaped Gram-Negative Rods -- Campylobacter and Arcobacter -- Helicobacter -- Leptospira -- Borrelia -- Treponema and Brachyspira, Human Host-Associated Spirochetes -- General Approaches to Identification of Mycoplasma, Ureaplasma, and Obligate Intracellular Bacteria -- Mycoplasma and Ureaplasma -- Chlamydiaceae -- Rickettsia and Orientia -- Ehrlichia, Anaplasma, and Related Intracellular Bacteria -- Coxiella -- Tropheryma whipplei -- Antibacterial Agents -- Mechanisms of Resistance to Antibacterial Agents -- Susceptibility Test Methods: General Considerations -- Susceptibility Test Methods: Dilution and Disk Diffusion Methods -- Antimicrobial Susceptibility Testing Systems -- Special Phenotypic Methods for Detecting Antibacterial Resistance -- Susceptibility Test Methods: Fastidious Bacteria -- Susceptibility Test Methods: Anaerobic Bacteria -- Susceptibility Test Methods: Mycobacteria, Nocardia, and Other Actinomycetes -- Molecular Detection of Antibacterial Drug Resistance. V. 2: Taxonomy and Classification of Viruses -- Specimen Collection, Transport, and Processing: Virology -- Reagents, Stains, Media, and Cell Cultures: Virology -- Algorithms for Detection and Identification of Viruses -- Human Immunodeficiency Viruses -- Human T-Cell Lymphotropic Viruses -- Influenza Viruses -- Parainfluenza and Mumps Viruses -- Respiratory Syncytial Virus and Human Metapneumovirus -- Measles and Rubella Viruses -- Enteroviruses and Parechoviruses -- Rhinoviruses -- Coronaviruses -- Hepatitis A and E Viruses -- Hepatitis C Virus -- Gastroenteritis Viruses -- Rabies Virus -- Arboviruses -- Hantaviruses -- Arenaviruses and Filoviruses -- Herpes Simplex Viruses and Herpes B Virus -- Varicella-Zoster Virus -- Human Cytomegalovirus -- Epstein-Barr Virus -- Human Herpesviruses -- Adenoviruses -- Human Papillomaviruses -- Human Polyomaviruses -- Parvovirus B19 and Bocaviruses -- Poxviruses -- Hepatitis B and D Viruses -- Transmissible Spongiform Encephalopathies -- Antiviral Agents -- Mechanisms of Resistance to Antiviral Agents -- Susceptibility Test Methods: Viruses -- Taxonomy and Classification of Fungi -- Specimen Collection, Transport, and Processing: Mycology -- Reagents, Stains, and Media: Mycology -- General Approaches for Direct Detection and Identification of Fungi -- Candida, Cryptococcus, and Other Yeasts of Medical Importance -- Pneumocystis -- Aspergillus and Penicillium -- Fusarium and Other Opportunistic Hyaline Fungi -- Agents of Systemic and Subcutaneous Mucormycosis and Entomophthoromycosis -- Histoplasma, Blastomyces, Coccidioides, and Other Dimorphic Fungi Causing Systemic Mycoses -- Trichophyton, Microsporum, Epidermophyton, and Agents of Superficial Mycoses -- Curvularia, Exophiala, Scedosporium, Sporothrix, and Other Melanized Fungi -- Fungi Causing Eumycotic Mycetoma -- Mycotoxins -- Lacazia, Lagenidium, Pythium, and Rhinosporidium -- Microsporidia -- Antifungal Agents -- Mechanisms of Resistance to Antifungal Agents -- Susceptibility Test Methods: Yeasts and Filamentous Fungi -- Taxonomy and Classification of Human Parasitic Protozoa and Helminths -- Specimen Collection, Transport, and Processing: Parasitology -- Reagents, Stains, and Media: Parasitology -- General Approaches for Detection and Identification of Parasites -- Plasmodium and Babesia -- Leishmania and Trypanosoma -- Toxoplasma -- Pathogenic and Opportunistic Free-Living Amebae -- Intestinal and Urogenital Amebae, Flagellates, and Ciliates -- Cystoisospora, Cyclospora, and Sarcocystis -- Cryptosporidium -- Nematodes -- Filarial Nematodes -- Cestodes -- Trematodes -- Less Common Helminths -- Arthropods of Medical Importance -- Antiparasitic Agents -- Mechanisms of Resistance to Antiparasitic Agents -- Susceptibility Test Methods: Parasites.
- Marine microbiology 2001ScienceDirect
- Mechanisms of epithelial defense 2005Karger
- Medical microbiology 2005Thieme Book
- Medical microbiology. 18th ed. 2012ClinicalKeyMicrobiology and medicine -- Morphology and nature of micro-organisms -- Classification, identification and typing of micro-organisms -- Bacterial growth, physiology and death -- Antimicrobial agents -- Bacterial genetics -- Virus-cell interactions -- Immunological principles: Antigens and antigen recognition -- Innate and acquired immunity -- Immunity in viral infections -- Parasitic infections: Pathogenesis and immunity -- Immunity in bacterial infections -- Bacterial pathogenicity -- The natural history of infection -- Staphylococcus: Skin infections; osteomyelitis; bloodstream infection; food poisoning; foreign body infections; MRSA -- Streptococcus and enterococcus: Pharyngitis; scarlet fever; skin and soft tissue infections; streptococcal toxic shock syndrome; pneumonia; meningitis; urinary tract infections; rheumatic fever; post-streptococcal glomerulonephritis -- Coryneform bacteria, listeria and erysipelothrix: Diphtheria; listeriosis; erysipeloid -- Mycobacterium: Tuberculosis; leprosy -- Environmental mycobacteria: Opportunist disease -- Actinomyces, nocardia and tropheryma: Actinomycosis; nocardiasis; Whipple's disease -- Bacillus: Anthrax; food poisoning -- Clostridium: Gas gangrene; tetanus; food poisoning; pseudomembranous colitis -- Neisseria and moraxella: Meningitis; septicaemia; gonorrhoea; respiratory infections -- Salmonella: Food poisoning; enteric fever -- Shigella: Bacillary dysentery -- Escherichia: Urinary tract infection; travellers' diarrhoea; haemorrhagic colitis; haemolytic uraemic syndrome -- Klebsiella, enterobacter, proteus and other enterobacteria: Pneumonia; urinary tract infection; opportunist infection -- Pseudomonads and non-fermenters: Opportunist infection; cystic fibrosis; melioidosis -- Campylobacter and helicobacter: Enteritis; polyneuropathy; gastritis; peptic ulcer disease; gastric cancer -- Vibrio, mobiluncus, gardnerella and spirillum: Cholera; vaginosis; rat bite fever -- Haemophilus: Respiratory infections; meningitis; chancroid -- Bordetella: Whooping cough -- Legionella: Legionnaires' disease; Pontiac fever -- Brucella, bartonella and streptobacillus: Brucellosis; Oroya fever; trench fever; cat scratch disease; bacillary angiomatosis; rat bite fever -- Yersinia, pasteurella and francisella: Plague; pseudotuberculosis; mesenteric adenitis; pasteurellosis; tularaemia -- Non-sporing anaerobes: Wound infection; periodontal disease; abscess; normal flora -- Treponema and borrelia: Syphilis; yaws; relapsing fever; Lyme disease -- Leptospira: Leptospirosis; Weil's disease -- Chlamydia: Genital and ocular infections; infertility; atypical pneumonia -- Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever -- Mycoplasmas: Respiratory and genital tract infections -- Adenoviruses: Respiratory disease; conjunctivitis; gut infections -- Herpesviruses: Herpes simplex; varicella and zoster; infectious mononucleosis; B cell lymphomas; cytomegalovirus disease; exanthem subitum; Kaposi's sarcoma; herpes B -- Poxviruses: Smallpox; molluscum contagiosum; parapoxvirus infections -- Papillomaviruses and polyomaviruses: Warts: warts and cancers; polyomavirus associated nephropathy; progressive multifocal leuco-encephalopathy -- Hepadnaviruses: Hepatitis B virus infection; hepatitis delta virus infection -- Parvoviruses: B19 infection; erythema infectiosum -- Picornaviruses: Meningitis; paralysis; rashes; intercostal myositis; myocarditis; infectious hepatitis; common cold -- Orthomyxoviruses: Influenza -- Paramyxoviruses: Respiratory infections; mumps; measles; Hendra/Nipah disease -- Arboviruses: alphaviruses, flaviviruses and bunyaviruses: Encephalitis; yellow fever; dengue; haemorrhagic fever; miscellaneous tropical fevers; undifferentiated fever -- Hepaciviruses and hepeviruses: Hepatitis C and E viruses; non-A, non-B hepatitis -- Arenaviruses and filoviruses: Viral haemorrhagic fevers -- Reoviruses: Gastroenteritis -- Retroviruses: Acquired immune deficiency syndrome; HTLV-1 -- Caliciviruses and astroviruses: Diarrhoeal disease -- Coronaviruses -- Rhabdoviruses -- Togaviruses: Rubella -- Prion diseases (transmissible spongiform encephalopathies): Creutzfeldt-Jakob disease; Gerstmann-Sträussler-Scheinker syndrome; fatal familial insomnia; iatrogenic Creutzfeldt-Jakob disease; kuru; variant Creutzfeldt-Jakob disease; bovine spongiform encephalopathy; scrapie-- Fungi: Superficial, subcutaneous and systemic mycoses -- Protozoa: Malaria; toxoplasmosis; cryptosporidiosis; amoebiasis; trypanosomiasis; leishmaniasis; giardiasis; trichomoniasis -- Helminths: Intestinal worm infections; filariasis; schistosomiasis; hydatid disease -- Arthropods: Arthropod-borne diseases; ectoparasitic infections; allergy -- Infective syndromes -- Diagnostic procedures -- Strategy of antimicrobial chemotherapy -- Epidemiology and control of community infections -- Hospital infection -- Immunization.
- Medical microbiology. 7th edition. 2013ClinicalKeyQuickly learn the microbiology fundamentals you need to know with this 7th Edition, by Dr. Patrick R. Murray, Dr. Ken S. Rosenthal, and Dr. Michael A. Pfaller. Newly reorganized to correspond with integrated curricula and changing study habits, this practical and manageable text is clearly written and easy to use, presenting clinically relevant information about microbes and their diseases in a succinct and engaging manner. Learn the most up-to-date and relevant information in medical microbiology. Study efficiently thanks to a reorganized format that places review chapters at the beginning of each section and review questions at the end of each chapter. Focus on clinical relevance with new interactive case presentations to introduce each of the microbial pathogens that illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Visualize the clinical presentations of infections with new and updated clinical photographs, images, and illustrations.
- Metagenomics-- sequences from the environment 2006NCBI BookshelfAcid mine drainage biofilm -- Waseca County farm soil -- Whale fall community -- Methane-oxidizing archaea -- Human fecal virus -- Sargasso Sea marine microbial metagenome -- Human distal gut microbiome -- Enhanced biological phosphorus removal (EBPR) sludge community -- Mouse gut microbiota metagenome.
- Microbial biochemistry. 2nd ed. 2011SpringerBacterial growth -- The outer membrane of gram-negative bacteria and the cytoplasmic membrane -- Peptidoglycan synthesis and cell division -- Cellular permeability -- Allosteric enzymes -- Glycolysis, gluconeogenesis and glycogen synthesis -- The pentose phosphate and Entner-Doudoroff pathways -- The tricarboxylic acid cycle and the glyoxylate bypass -- ATP-generating processes : respiration and fermentation -- Biosynthesis of lipids -- Iron-sulfur proteins -- The archaea -- Methanogens and methylotrophs -- Enzyme induction in catabolic systems -- Transcription : RNA polymerase -- Negative regulation -- Enzyme repression in anabolic pathways -- Positive regulation -- The ribosomes -- The genetic code, the transfer RNAs and the aminoacyl-tRNA-synthetases -- Attenuation -- Riboswitches -- The biological fixation of nitrogen -- How biosynthetic pathways have been established -- The aspartic acid family of amino acids : biosynthesis -- Regulation of the biosynthesis of the amino acids of the aspartic acid family in Enterobacteriaceae -- Other patterns of regulation of the synthesis of amino acids of the aspartate family -- Biosynthesis of the amino acids of the glutamic acid family and its regulation -- Biosynthesis of amino acids derived from phosphoglyceric acid and pyruvic acid -- Selenocysteine and selenoproteins -- Biosynthesis of aromatic amino acids and its regulation -- The biosynthesis of histidine and its regulation -- The biosynthesis of nucleotides -- The biosynthesis of deoxyribonucleotides -- Biosynthesis of some water-soluble vitamins and of their coenzyme forms -- Biosynthesis of carotene, vitamin A, sterols, ubiquinones and menaquinones -- Biosynthesis of the tetrapyrrole ring system -- Biosynthesis of cobalamins including vitamin B12 -- Interactions between proteins and DNA -- Evolution of biosynthetic pathways.
- Microbial drug resistance 2013Future MedAntibiotic resistance : postantibiotic era is here / Vladimir Krcmery -- Current challenges in treating methicillin-resistant Staphylococcus aureus : what are the options? / Noha E.I. Sakka & Ian M . Gould -- Antimicrobial-resistant Streptococcus pneumoniae : trends and management / Michael R. Jacobs -- Emergence and management of drug-resistant enterococcal infections / William R. Miller, Barbara E. Murray & Cesar A. Arias -- Enterobacteriaceae that produce newer b-lactamases / Johann D.D. Pitout -- Extensively drug-resistant tuberculosis : new strains, new challenges / Megan Coffee -- Clinical significance of extended-spectrum b-lactamases / Jesés Rodréguez-Baño, Belén Gutiérrez, Lorena Lépez-Cerero & Alvaro Pascual -- Plasmid-mediated quinolone resistance / José Manuel Rodréguez-Marténez, Maréa Eliecer Cano, Jorge Calvo, Álvaro Pascual & Luis Marténez-Marténez -- Antibiotic resistance in the absence of antimicrobial use / Lucia Pallecchi, Alessandro Bartoloni, Eduardo Gotuzzo & Gian Maria Rossolini -- Resistance in bacteria of the food chain : epidemiology and control strategies / Lina Maria Cavaco & Frank Møller Aarestrup -- Measures to prevent antimicrobial resistance / Vhairi M. Bateman & Ian M. Gould -- Where does novel antibiotics R&D stand among other pharmaceutical products? / Glenn S. Tillotson -- Resistance to antiretroviral drugs / Manuela Colafigli, Simona Di Giambenedetto & Roberto Cauda -- Index.
- Microbial enzymes and biotransformations 2005Springer Protocols
- Microbial food contamination. 2nd ed. 2008CRCnetBASEPreface: Food--A Necessity and a Threat -- Editor -- Contributors -- Section I. Instances and Nature of Microbial Food Contamination -- 1. PulseNet and Emerging Foodborne Diseases / Efrain M. Ribot, Eija Hyytia-Trees, and Kara Cooper -- 2. Pathogenic Mechanisms of the Enterohemorrhagic
- Microbial forensics 2005ScienceDirect
- Microbial gene essentiality protocols and bioinformatics 2008Springer ProtocolsOverview of whole-genome essentiality analysis / Karen Joy Shaw -- Pt. I. Experimental protocols. IA. Populational genome-wide essentiality screens. Transposon-based strategies for the identification of essential bacterial genes / William S. Reznikoff and Kelly M. Winterberg -- Identification and analysis of essential genes in Haemophilus influenzae / Sandy M.S. Wong and Brian J. Akerley -- Transposon site hybridization in Mycobacterium tuberculosis / Jeffrey P. Murry ... [et al.] -- Essential genes in the infection model of Pseudomonas aeruginosa PCR-based signature-tagged mutagenesis / François Sanschagrin, Irena Kukavica-Ibrulj, and Roger C. Levesque -- Whole-genome detection of conditionally essential and dispensable genes in Escherichia coli via genetic footprinting / Michael D. Scholle and Svetlana Y. Gerdes -- Generating a collection of insertion mutations in the Staphylococcus aureus genome using bursa aurealis / Taeok Bae ... [et al.] -- Multipurpose transposon insertion libraries for large-scale analysis of gene function in yeast / Anuj Kumar -- IB. Systematic collections of knockout mutants. How to make a defined near-saturation mutant library. Case 1: Pseudomonas aeruginosa PAO1 / Michael A. Jacobs -- Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality / Nicole T. Liberati ... [et al.] -- The construction of systematic in-frame, single-gene knockout mutant collection in Escherichia coli K-12 / Tomoya Baba and Hirotada Mori -- The applications of systematic in-frame, single-gene knockout mutant collection of Escherichia coli K-12 / Tomoya Baba ... [et al.] -- A novel, simple, high-throughput method for isolation of genome-wide transposon insertion mutants of Escherichia coli K-12 / Takeyoshi Miki, Yoshihiro Yamamoto, and Hideo Matsuda -- High-throughput creation of a whole-genome collection of yeast knockout strains / Angela M. Chu and Ronald W. Davis -- Analysis of genetic interactions on a genome-wide scale in budding yeast: diploid-based synthetic lethality analysis by microarray / Pamela B. Meluh ... [et al.] -- IC. Genome minimization. Scarless engineering of the Escherichia coli genome / Tamás Fehér ... [et al.] -- Minimization of the Escherichia coli genome using the Tn5-targeted Cre/loxP excision system / Byung Jo Yu and Sun Chang Kim -- Construction of long chromosomal deletion mutants of Escherichia coli and minimization of the genome / Jun-ichi Kato and Masayuki Hashimoto -- ID. Conditional knockouts. Identification of essential genes in Staphylococcus aureus by construction and screening of conditional mutant library / Dezhong Yin and Yinduo Ji -- Techniques for the isolation and use of conditionally expressed antisense RNA to achieve essential gene knockdowns in Staphylococcus aureus / Allyn Forsyth and Liangsu Wang -- Introduction of conditional lethal amber mutations in Escherichia coli / Christopher D. Herring -- Pt. II. Bioinformatics. IIA. Statistics. Statistical methods for building random transposon mutagenesis libraries / Oliver Will -- Statistical evaluation of genetic footprinting data / Gábor Balázsi -- Modeling competitive outgrowth of mutant populations : why do essentiality screens yield divergent results? / Alexander I. Grenov and Svetlana Y. Gerdes -- Statistical analysis of fitness data determined by TAG hybridization on microarrays / Brian D. Peyser, Rafael Irizarry, and Forrest A. Spencer -- IIB. Data integration and modeling. Profiling of Escherichia coli chromosome database / Yukiko Yamazaki, Hironori Niki, and Jun-ichi Kato -- Gene essentiality analysis based on DEG, a database of essential genes / Chun-Ting Zhang and Ren Zhang -- Detection of essential genes in Streptococcus pneumoniae using bioinformatics and allelic replacement mutagenesis / Jae-Hoon Song and Kwan Soo Ko -- Design and application of genome-scale reconstructed metabolic models / Isabel Rocha, Jochen Förster, and Jens Nielsen -- Predicting gene essentiality using genome-scale in silico models / Andrew R. Joyce and Bernhard Ø. Palsson -- Comparative approach to analysis of gene essentiality / Andrei L. Osterman and Svetlana Y. Gerdes.
- Microbial genomics and drug discovery 2003CRCnetBASE
- Microbial glycobiology structures, relevance and applications. 1st ed. 2009ScienceDirect
- Microbial imaging. 1st ed. 2005ScienceDirect
- Microbial linear plasmids 2007Springer
- Microbial processes and products 2005Springer Protocols
- Microbial protein toxins 2005SpringerDiphtheria toxin, diphtheria-related fusion protein toxins, and the molecular mechanism of their action against eukaryotic cells -- Anthrax toxin and genetic aspects regulating its expression -- Shiga toxins and their mechanisms of cell entry -- Cholera toxin: mechanisms of entry into host cells -- ExoU: a cytotoxin delivered by the type III secretion system of pseudomonas aeruginosa -- Staphylococcal alpha-toxin -- S. cerevisiae K28 toxin- a secreted virus toxin of the A/B family of protein toxins -- Kluyveromyces lactis zymocin and other plasmid-encoded yeast killer toxins -- The ustilago maydis killer toxins -- Zygocin- a monomeric protein toxin secreted by virus-infected zygosaccharomyces bailii -- Acidophilic structure and killing mechanism of the pichia farinosa killer toxin SMKT.
- Microbial safety of minimally processed foods 2003CRCnetBASE
- Microbial siderophores 2007Springer
- Chapter 1: Overview -- Chapter 2: Performance Criteria -- Chapter 3: Library-dependent Source Tracking Methods -- Chapter 4: Library-Independent Source Tracking Methods -- Chapter 5: Viruses as Tracers of Fecal Contamination -- Chapter 6: Phage Methods -- Chapter 7: Pathogenic Protozoa -- Chapter 8: Chemical-Based Fecal Source Tracking Methods -- Chapter 9: Statistical Approaches for Modeling in Microbial Source Tracking -- Chapter 10: Mitochondrial DNA as Source Tracking Markers of Fecal Contamination -- Chapter 11: Community Analysis-Based Methods -- Chapter 12: Public Perception of and Public Participation in Microbial Source Tracking -- Chapter 13: Use of Microbial Source Tracking in the Legal Arena: Benefits and Challenges -- Chapter 14: Applications of Microbial Source Tracking in the TMDL Process -- Chapter 15: Relating MST Results to Fecal Indicator Bacteria, Pathogens, and Standards -- Chapter 16: Minimizing Microbial Source Tracking at All Costs -- Chapter 17: Environmental Persistence and Naturalization of Fecal Indicator Organisms -- Chapter 18: Agricultural and Rural Watersheds -- Chapter 19: Case Studies of Urban and Suburban Watersheds -- Chapter 20: Beaches and Coastal Environmenta -- Chapter 21: Source tracking in Australia and New Zealand: Case Studies -- Chapter 22: Microbial Source Tracking in China and Developing Nations -- Chapter 23: A National Security Perspective of Microbial Source Tracking -- Chapter 24: Applications of Quantitative Microbial Source Tracking (QMST) and Quantitative Microbial Risk Assessment (QMRA) -- Chapter 25: Food Safety and Implications for Microbial Source Tracking -- Chapter 26: Training Future Scientists: Teaching Microbial Source Tracking (MST) to Undergraduates -- Index.
- Microbial stress adaptation and food safety 2003CRCnetBASE
- Microbial synthetic biology. First edition. [1st ed.] 2013ScienceDirectComputational intelligence in the design of synthetic microbial genetic systems / Jennifer S. Hallinan -- Constraints in the design of the synthetic bacterial chassis / Antoine Danchin and Agnieszka Sekowska -- Social dimensions of microbial synthetic biology / Jane Calvert, Emma Frow -- Bacillus subtilis: model gram-positive synthetic biology chassis / Colin R. Harwood, Suzanne Pohl, Wendy Smith, Anil Wipat -- Engineering microbial biosensors / Lisa Goers, Nicolas Kylilis, Marios Tomazou, Ke Yan Wen, Paul Freemont, Karen Polizzi -- Noise and stochasticity in gene expression: a pathogenic fate determinant / Mikkel Girke Jørgensen, Renske van Raaphorst, Jan-Willem Veening -- Platforms for genetic design automation / Chris J. Myers.
- Microbicides for prevention of HIV infection 2014SpringerOne of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.
- Microbiological analysis of red meat, poultry and eggs 2007CRCnetBASE
- Microbiology and aging clinical manifestations 2009Springer
- Microbiology monographs v. 1-, 2006-Springer
- Microbiology of fruits and vegetables 2005CRCnetBASE
- Microbiology of waterborne diseases microbiological aspects and risks. Second edition. [2nd ed.] 2014ScienceDirectThe second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus. Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen. Contains new material on antimicrobial resistance and biofilms. Covers drinking water and both marine and freshwater recreational bathing waters.
- Microbiology of wounds 2010CRCnetBASEAn introduction to the world of microbiology and biofilmology / Steven L. Percival, John G. Thomas, and David Williams -- Human skin and microbial flora / Rose A. Cooper and Steven L. Percival -- An introduction to wounds / Michel H.E. Hermans and Terry Treadwell -- Burn wound management / Michel H.E. Hermans -- Cell biology of normal and impaired healing / Keith Moore -- The microbiology of wounds / Steven L. Percival and Scott E. Dowd -- Types of wounds and infections / Randall D. Wolcott ... [et al.] -- Biofilms and significance to wound healing / Keith F. Cutting ... [et al.] -- Wounds, enzymes, and proteases / Steven L. Percival and Christine A. Cochrane -- Wound healing immunology and biofilms / Emma J. Woods ... [et al.] -- Antimicrobial interventions for wounds / Steven L. Percival, Rose A. Cooper, and Benjamin A. Lipsky -- Wound dressings and other topical treatment modalities in bioburden control / Richard White -- Factors affecting the healing of chronic wounds : an iconoclastic view / Marissa J. Carter and Caroline E. Fife.
- Microorganisms in home and indoor work environments diversity, health impacts, investigation and control. 2nd ed. 2011CRCnetBASEMachine generated contents note: ch. 1 Microorganisms in air -- 1.1.Microorganisms in outdoor air / B. Flannigan -- 1.2.Microorganisms in indoor air / B. Flannigan -- 1.3.Pollen in indoor air / A. Rantio-Lehtimaki -- ch. 2 Microorganisms in homes and work environments -- 2.1.Microbial growth in indoor environments / J.D. Miller -- 2.2.Bacteria and other bioaerosols in industrial workplaces / J.R.M. Swan -- 2.3.Remediation and control of microbial growth in problem buildings / P.R. Morey -- ch. 3 Airborne microorganisms and disease -- 3.1.Allergenic microorganisms and hypersensitivity / J.H. Day -- 3.2.Occupational respiratory disease: hypersensitivity pneumonitis and other forms of interstitial lung disease / B. Flannigan -- 3.3.Respiratory tract infections caused by indoor fungi / R.C. Summerbell -- ch. 4 Microbiological investigation of indoor environments -- 4.1.Mycological investigations of indoor environments / J.D. Miller -- 4.2.Molecular methods for bioaerosol characterization / J.A. Scott -- 4.3.Isolation and identification of fungi / J. Houbraken -- 4.4.Analysis of microbial volatile organic compounds / T.J. Ryan -- 4.5.Analysis for toxins and inflammatory compounds / J.D. Miller -- 4.6.Interpreting sampling data in investigations of indoor environments: selected case studies / P.R. Morey -- ch. 5 Common and important species of Actinobacteria and fungi in indoor environments -- Common and important species of fungi and actinomycetes in indoor environments / J.D. Miller -- Descriptions and illustrations of common fungi and actinomycetes.
- Mims' Medical microbiology. 5th ed. 2013ClinicalKeyUsing a clinically relevant, systems-based approach, this medical textbook accessibly explains the microbiology of the agents that cause diseases and the diseases that affect individual organ systems. With lavish illustrations and straightforward, accessible explanations, Richard Goering makes this complex subject simple to understand and remember. 150 multiple choice review questions. "Pathogen Parade" and many other features to enhance learning and retention. Enhance your learning and absorb complex information in an interactive, dynamic way. Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventive medicine. A completely re-written chapter on this topic keeps abreast of the very latest findings.
- This book focuses on the function of antibodies in vivo. Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. These new results dramatically changed our view of how antibodies function in vivo. The importance of this class of molecules is demonstrated by the heightened susceptibility to infections of humans and mice with an altered capacity to generate pathogen specific antibody responses. Thus, the majority of our currently available vaccines, such as vaccines against influenza, measles and hepatitis focus on the generation of long lasting antibody responses. Recent evidence from a variety of in vivo model systems and from human patient cohorts has highlighted the exclusive role of cellular Fc-receptors for certain immunoglobulin isotypes and subclasses. With the recent discovery of a human Fc-receptor for IgM all different human immunoglobulin isotypes now have a cellular receptor, providing a feedback mechanism and link between antibodies and the cellular components of the immune system. Moreover it has become clear the complement and Fc-receptor system are tightly connected and regulate each other to ensure a well balanced immune response. Among the immunoglobulin isotypes IgG plays a very important protective role against microbial infections and also as a therapeutic agent to kill tumor cells or autoantibody producing B cells in autoimmune disease. Transfer of our knowledge about the crucial function of Fc-receptors has led to the production of a second generation of therapeutic antibodies with enhanced binding to this class of receptors. Binding of antibodies to Fc-receptors leads to the recruitment of the potent pro-inflammatory effector functions of cells from the innate immune system. Hence, Fc-receptors link the innate and adaptive immune system, emphasizing the importance of both arms of the immune system and their crosstalk during anti-microbial immune responses. Besides this pro-inflammatory activity immunoglobulin G (IgG) molecules are long known to also have an anti-inflammatory function. This is demonstrated by the use of high dose intravenous immunoglobulins as a therapeutic agent in many human autoimmune diseases. During the past five years several new insights into the molecular and cellular pathways of this anti-inflammatory activity were gained radically changing our view of IgG function in vivo. Several lines of evidence suggest that the sugar moiety attached to the IgG molecule is responsible for these opposing activities and may be seen as a molecular switch enabling the immune system to change IgG function from a pro- to an anti-inflammatory activity. There is convincing evidence in mice and humans that aberrant IgG glycosylation could be an important new pathway for understanding the impaired antibody activity during autoimmune disease. Besides this tremendous increase in basic knowledge about factors influencing immunoglobulin activity the book will also provide insights into how these new insights might help to generate novel therapeutic approaches to enhance IgG activity for tumor therapy on the one hand, and how to block the self-destructive activity of IgG autoantibodies during autoimmune disease on the other hand.
- Molecular biology of fungal development 2002CRCnetBASE
- Molecular cellular microbiology 2002ScienceDirect
- Molecular detection of human fungal pathogens 2011CRCnetBASEPt. 1. Ascomycota -- pt. 2. Bastidiomycota -- pt. 3. Entomohpthoromycotina and Muscoromyotina -- pt. 4. Microsporidia -- pt. 5. Oomycota, Chlorophyta, and Mesomycetozoea -- pt. 6. Panfungal and drug resistance detection.
- Molecular identification of fungi 2010Springer
- Molecular mechanisms in Legionella pathogenesis 2014SpringerLegionnaires' disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.
- Molecular medical microbiology 2002ScienceDirect
- Molecular microbiology of heavy metals 2007Springer
- Molecular virology 2013SpringerThe book gives a comprehensive overview on the knowledge of virus infection relevant for humans and animals. For each virus family the molecular details of the virus particle and the viral replication cycle are described. In the case of virus types with relevance for human and/or animal health the data on molecular biology, genetics and virus-cell interaction are combined with those concerning, pathogenesis, epidemiology, clinics, prevention and therapy.
- Why the investigation was started -- Materials and methodology -- Evidence not recorded on videotape -- The phenomenon of the disappearing hair follicles -- Particles entering the eyes -- Particles exiting the eyes -- A substance that transverses the optic globe -- The irregular iris -- Particles that exit the feet -- Particles that enter the feet -- The microorganism mobility : an internal propulsion system -- Green feet illuminate the role of the epidermis in the life-cycle of the microorganism -- Coated hairs under the microscope -- The micro organism possibly growing on a piece of cocaine -- A summary of the observations -- The structure of the microorganism -- A model accounting for the observed phenomena -- Is there a cure? -- Future considerations : a microorganism as an etiology for delusional parasitosis.
- Morphogenesis and pathogenicity in fungi 2012SpringerThis book combines state-of-the-art expertise from a variety of diverse pathogen model systems to provide an update to our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.
- Mucosal immunology of acute bacterial pneumonia 2013SpringerIn contrast to the substantial literature that focuses upon innate immune signaling in the gut, there is remarkably less known about the response of the airway to bacterial pathogens. The purpose of this book will be to review the current status of theunderstanding of the pathogenesis of acute bacterial pneumonia, slanted toward the mucosal immunology of these infections. It will describe, in general, the signaling cascades that control the proinflammatory response to bacterial infection in the lung. How innate immune signaling is orchestrated in response to specific common airway pathogens is addressed, targeting Staphylococus aureus (including MRSA), Streptococcus pneumoniae and Klebsiella pneumoniae. By describing the general immunological responses to conserved bacterial components and then detailing how specific organisms cause infection, this book provides a targeted but comprehensive review of this important topic.
- Multiplication of RNA plant viruses 2006Springer
- Myc/Max/Mad transcription factor network 2006SpringerMaking Myc / J. Liu and D. Levens -- Transcriptional activation by the Myc oncoprotein / M. D. Cole and M. A. Nikiforov -- Mechanisms of transcriptional repression by Myc / D. Kleine-Kohlbrecher, S. Adhikary and M. Eilers -- The mad side of the Max network : antogonizing the function of Myc and more / S. Rottmann and B. Luscher -- Structural aspects of interactions with the Myc/Max/Mad network / S. K. Nair and S. K. Burley -- Myc target transcriptomes / L. A. Lee and C. V. Dang -- c-Myc, genome instability, and tumorigenesis : the devil is in the details / M. Wade and G. M. Wahl -- Lessons learned from Myc/Max/Mad knockout mice / M. Pirity, J. K. Blanck and N. Schreiber-Agus -- Myc/Max/Mad in invertebrates : the evolution of the Max network / P. Gallant -- The mix network : evidence for a parallel Max-like transcriptional network that regulates energy metabolism / A. N. Billin and D. E. Ayer.
- Mycota v. 1, 4, , 6, 8-10, 13-15, 2006-12.Springer
- National Institute of Allergy and Infectious Diseases, NIH. Volume 1-3 v. 1-3, 2008-2010.Springerv. 2, 2009 Springerv. 3, 2010 Springerv. 1. Frontiers in research -- v. 2. Impact on Global Health -- v. 3. Intramural research.
- Negative co-receptors and ligands 2011SpringerTIM-3 and its regulatory role in immune responses / Chen Zhu, Ana C. Anderson and Vijay K. Kuchroo -- Role of PD-1 in regulating T-cell immunity / Hyun-Tak Jin, Rafi Ahmed and Taku Okazaki -- The role of IL-10 in regulating immunity to persistent viral infections / Elizabeth B. Wilson and David G. Brooks -- Inhibitory Ly49 receptors on mouse natural killer cells / Mark T. Orr and Lewis L. Lanier -- Immunoregulatory roles for Fc receptor-like molecules / Götz R.A. Ehrhardt and Max D. Cooper -- Fc[gamma]Rs in health and disease / Falk Nimmerjahn and Jeffrey V. Ravetch -- TGF-[beta] function in immune suppression / Akihiko Yoshimura and Go Muto.
- New antibiotic targets 2008Springer Protocols
- New approaches for the generation and analysis of microbial typing data 2001ScienceDirectAn introduction to the generation and analysis of microbial typing data / Lenie Dijkshoorn and Kevin Towner -- Theoretical aspects of pattern analysis / Arjen van Ooyen -- Setting-up intra- and inter-laboratory databases of electrophoretic profiles / Herre F. Heersma, Kristin Kremer, Dick van Soolingen and John Hauman -- Fingerprinting of microorganisms by protein and lipopolysaccharide SDS-PAGE / Lenie Dijkshoorn -- rRNA gene restriction pattern determination (ribotyping) and computer interpretation / Patrick A.D. Grimont and Francine Grimont -- Generation and analysis of RAPD fingerprinting profiles / Kevin Towner and Hajo Grundmann -- Analysis of microbial genomic macrorestriction patterns by pulsed-field gel electrophoresis (PFGE) typing / Marc J. Struelens, Raf De Ryck and Ariane Deplano -- Selective restriction fragment amplification by AFLPTM / Paul J.D. Janssen -- Application and analysis of ARDRA patterns in bacterial identification, taxonomy and phylogeny / Mario Vaneechoutte and Marc Heyndrickx -- Insertion sequence (IS) typing and oligotyping / Nicholas A. Saunders -- Molecular characterisation of microbial communities based on 16S rRNA sequence diversity / Erwin G Zoetendal, Antoon DL Akkermans and Willem M de Vos -- From multilocus enzyme electrophoresis to multilocus sequence typing / Dominique A. Caugant.
- New approaches to prokaryotic systematics. First edition. [1st ed.] 2014ScienceDirectChapter 1. The Need for Change: Embracing the Genome / William B. Whitman -- Chapter 2. An Introduction to Phylogenetics and the Tree of Life / Tom A. Williams, Sarah E. Heaps -- Chapter 3. The All-Species Living Tree Project / Pablo Yarza, Raul Munoz -- Chapter 4. 16S rRNA Gene-Based Identification of Bacteria and Archaea using the EzTaxon Server / Mincheol Kim, Jongsik Chun -- Chapter 5. Revolutionizing Prokaryotic Systematics Through Next-Generation Sequencing / Vartul Sangal, Leena Nieminen, Nicholas P. Tucker, Paul A. Hoskisson -- Chapter 6. Whole-Genome Analyses: Average Nucleotide Identity / David R. Arahal -- Chapter 7. Whole-Genome Sequencing for Rapid and Accurate Identification of Bacterial Transmission Pathways / Simon R. Harris, Chinyere K. Okoro -- Chapter 8. Identification of Conserved Indels that are Useful for Classification and Evolutionary Studies / Radhey S. Gupta -- Chapter 9. Reconciliation Approaches to Determining HGT, Duplications, and Losses in Gene Trees / Olga K. Kamneva, Naomi L. Ward -- Chapter 10. Multi-Locus Sequence Typing and the Gene-by-Gene Approach to Bacterial Classification and Analysis of Population Variation / Alison J. Cody, Julia S. Bennett, Martin C.J. Maiden -- Chapter 11. Multi-locus Sequence Analysis: Taking Prokaryotic Systematics to the Next Level / Xiaoying Rong, Ying Huang -- Chapter 12. Bacterial Typing and Identification By Genomic Analysis of 16S-23S rRNA Intergenic Transcribed Spacer (ITS) Sequences / Volker Gürtler, Gangavarapu Subrahmanyam, Malathi Shekar, Biswajit Maiti, Indrani Karunasagar -- Chapter 13. MALDI-TOF Mass Spectrometry Applied to Classification and Identification of Bacteria / Peter Schumann, Thomas Maier -- Chapter 14. Continuing Importance of the “Phenotype” in the Genomic Era / Peter Kämpfer -- Index.
- New insights in medical mycology 2007SpringerImmunity to fungi -- In vitro models to analyse fungal infection -- Insects as models for studying the virulence of fungal pathogens of humans -- Novel antifungal therapies -- Candida albicans: new insights in infection, disease, and treatment -- Pathogenesis of Cryptococcus neoformans -- Zygomycetes -- Virulence of Aspergillus fumigatus -- Biology of the thermally dimorphic fungal pathogen Penicillium marneffei -- Immune responses to dermatophytoses -- Insights in Paracoccidioides brasiliensis pathogenicity -- Fusarium and Scedosporium: emerging fungal pathogens.
- New perspectives in regeneration 2013SpringerMechanisms of Vessel Regression: Toward an Understanding of the Resolution of Angiogenesis / Mateusz S. Wietecha, Wendy L. Cerny, Luisa A. DiPietro -- Wound Healing in Mammals and Amphibians: Toward Limb Regeneration in Mammals / Aiko Kawasumi, Natsume Sagawa, Shinichi Hayashi -- Cellular Plasticity During Vertebrate Appendage Regeneration / James R. Monaghan, Malcolm Maden -- Cell Signaling Pathways in Vertebrate Lens Regeneration / Jonathan J. Henry, Alvin G. Thomas, Paul W. Hamilton -- Regenerative Medicine: Challenges and Perspectives for Successful Therapies / S. Viswanathan, C. Joshi -- Employing the Biology of Successful Fracture Repair to Heal Critical Size Bone Defects / Jo Ann Cameron, Derek J. Milner, Jung Seok Lee -- Muscle Repair and Regeneration: Stem Cells, Scaffolds, and the Contributions of Skeletal Muscle to Amphibian Limb Regeneration / Derek J. Milner, Jo Ann Cameron -- Neural Regeneration / Melissa M. Steward, Akshayalakshmi Sridhar -- Teleost Fish as a Model System to Study Successful Regeneration of the Central Nervous System / Günther K. H. Zupanc, Ruxandra F. Sîrbulescu -- Epigenetics and Regeneration / Nobuyasu Maki, Hironobu Kimura -- Cell Cycle Regulation and Regeneration / Ellen Heber-Katz, Yong Zhang, Khamila Bedelbaeva.
- NF-kB in health and disease 2011SpringerUnderstanding the logic of I[kappa]B:NF-[kappa]B regulation in structural terms / Tom Huxford, Alexander Hoffmann and Gourisankar Ghosh -- NF-[kappa]B/Rel proteins and the humoral immune responses of Drosophila melanogaster / Sandhya Ganesan ... [et al.] -- Specialized chromatin patterns in the control of inflammatory gene expression / Gioacchino Natoli -- IKK regulation and human genetics / Giles Courtois and Alain Israel -- Control of NF-[kappa]B activity by proteolysis / Veronique Baud and Emmanuel Derudder -- NF-[kappa]B and Innate immunity / Anurupa Dev ... [et al.] -- NF-[kappa]B and mucosal homeostasis / Lars Eckmann and Andrew S. Neish -- IKK- and NF-[kappa]B-mediated functions in carcinogenesis / Melek C. Arkan and Florian R. Greten -- Macrophages and NF-[kappa]B in cancer / Toby Lawrence -- NF-[kappa]B in liver cancer : The plot thickens / Shlomi Finkin and Eli Pikarsky -- NF-[kappa]B as a target for oncogenic viruses / Shao-Cong Sun and Ethel Cesarman -- Inhibition of NF-[kappa]B signaling as a strategy in disease therapy / Thomas D. Gilmore and Michael R. Garbati.
- Nucleic acids and proteins in soil 2006Springer
- Pathogens in the sea: an overview / Colin B. Munn -- Diversity, sources, and detection of human bacterial pathogens in the marine environment / Janelle R. Thompson, Luisa A. Marcelino, and Martin F. Polz -- Biotic and abiotic effects / Lester W. Sinton -- Survival of enteric bacteria in seawater: molecular aspects / Yael Rozen and Shimshon Belkin -- Human pathogenic viruses in the marine environment / Albert Bosch, F. Xavier Abad, and Rosa M. Pinto -- Survival of viruses in the marine environment / Charles P. Gerba -- Zoonotic protists in the marine environment / Ronald Fayer and James M. Trout -- Marine and estuarine harmful algal blooms: impacts on human and animal health / Jan Landsberg, Fran Van Dolah, and Gregory Donelli -- Vibrio vulnificus / James D. Oliver -- Vibrio parahaemolyticus--seafood safety and associations with higher organisms / Firdausi Qadri ... [et al.] -- Global microbial ecology of vibrio cholerae / Rita R. Colwell -- Gram-positive bacteria in the marine environment / Maria del mar Lleo, Caterina Signoretto, and Pietro Canepari -- Fecal contamination in coastal areas: an engineering approach / M. Pommepuy ... [et al.] -- Retention of pathogenicity in viable nonculturable pathogens / Iddya Karunasagar and Indrani Karunasagar -- Thalassogenic infectious diseases caused by wastewater pollution of the marine environment / Hillel Shuval -- Bacterial pathogens of marine fish / Brian Austin -- Microbial diseases of corals / E. Rosenberg and Y. Barash -- Aquacultures and animal pathogens in the marine environment with emphasis on marine shrimp viruses / Jeffrey M. Lotz, Robin M. Overstreet, and D. Jay Grimes.
- One Health: the human-animal-environment interfaces in emerging infectious diseases. Food safety and security, and international and national plans for implementation of One Health activities 2013SpringerThe second volume on One Health explains in detail how to implement three key aspects of the One Health paradigm food safety and security, national plans for a holistic one health approach, and relevant new technologies and approaches. The fourteen chapters, each by an internationally recognized authority, are organized into three sections of four or five chapters each, that break new ground in clarifying precisely how One Health can become an operational reality in local, national and international public health initiatives. Section three begins with an international overview on food safety and security. The importance of a One Heath approach is then explained in relation to four specific problems?the growing prevalence of antibiotic resistance, bovine spongiform encephalopathy and pathogenic E.coli. Section four begins with the role of the Food and Agricultural Organization (FAO) in promoting One Health. The formulation and implementation of national plans for implementing the One Health paradigm are then set out for Africa, the Western Pacific, Southeast Asia and Mongolia. The final section of this two volume book is devoted to implementing new technologies and new approaches to One Health. A wide-ranging analysis considers the importance of climate change and a social-ecological systems approach, as well as how to operationalize One Health, how to move from emergency response to prevention at source, and how to implement an educational strategy that builds a foundation for One Health in emerging disease management. It is anticipated that this two volume book will become a benchmark for practitioners of One Health, empowering a balanced multidisciplinary approach to the complexities of the human-animal-environment interface.
- One health: the human-animal-environment interfaces in emerging infectious diseases. The concept and examples of a one health approach 2013SpringerOne Health: its origins and future -- One Health and emerging infectious diseases: clinical perspectives -- The historical, present, and future role of veterinarians in One Health -- The importance of understanding the human-animal interface -- The human environment interface: applying ecosystem concepts to health -- Wildlife: the need to better understand the linkages -- The economic value of One Health in relation to the mitigation of zoonotic disease risks -- The application of One Health approaches to henipavirus research -- H5N1 highly pathogenic avian influenza in Indonesia: retrospective considerations -- Rabies in Asia: the classical zoonosis -- Japanese encephalitis: on the One Health agenda -- Cost estimate of bovine tuberculosis to Ethiopia -- The pandemic H1N1 influenza experience -- One Health: the Hong Kong experience with avian influenza -- Clostridium difficile infection in humans and piglets: a 'One Health' opportunity -- Men, primates, and germs: an ongoing affair -- Erratum to: Cost estimate of bovine tuberculosis to Ethopia -- Index.
- An overview : identity from bacteria to belief -- The prokaryotes : viruses, hyperparasites and the origin of group identity -- Sensory systems (light, odor, pheromones) in communities of oceanic microbes -- Subjugation of the individual : prokaryotic group living : blooms, slime and mats -- Animal group identity : from slime to worms, emergence of the brain -- Group identity in aquatic animals : learning to belong -- Development of tetrapod group identity, the smell of self -- Origin of primate group identity : vision and the great ERV invasion -- Human group identity : language and a social mind.
- Orthopoxviruses pathogenic for humans 2005Springer
- Paleomicrobiology past human infections 2008SpringerGreat plagues of the past and remaining questions / Cheston B. Cunha and Burke A. Cunha -- Identification and interpretation of historical cemeteries linked to epidemics / Dominique Castex -- Archaeological proof of an abrupt mortality crisis : simultaneous deposit of cadavers, simultaneous deaths? / Henri Duday -- Molecular detection of past pathogens / Michel Drancourt and Didier Raoult -- Histologic detection of past pathogens / Hubert Lepidi -- Palaeomicrobiology of tuberculosis / Helen D. Donoghue -- Past leprae / Andreas G. Nerlich and Albert R. Zink -- Archaeology of human pathogens : palaeopathological appraisal of palaeoepidemiology / Olivier Dutour -- Past plague / Michel Drancourt and Didier Raoult -- Typhoid fever epidemic in ancient Athens / Manolis J. Papagrigorakis, Christos Yapijakis and Philippos N. Synodinos -- Dental pulp as a tool for the retrospective diagnosis of infectious diseases / Vu Dang La ... [et al.] -- History of influenza pandemics / Bruno Lina -- Human lice : Pediculus and Pthirus / Kosta Y. Mumcuoglu.
- Paramecium genetics and epigenetics 2008CRCnetBASEMating types in paramecium -- General description of the protista and of paramecium -- Methods of studying genetic processes in organisms of the paramecium Aurelia species group -- The determination of mating types in paramecium -- Symbionts and mitochondria of paramecium -- Determination of i-antigens -- Micronuclei and macronuclei -- Ribosomal RNA and DNA -- Cortical morphogenesis -- Behavior -- Epigenetics.
- Pasteurella multocida: Diseases and Pathogenesis / I. W. Wilkie, M. Harper, J. D. Boyce and B. Adler -- Pathogenomics of Pasteurella multocida / J. D. Boyce, T. Seemann, B. Adler and M. Harper -- The Key Surface Components of Pasteurella multocida: Capsule and Lipopolysaccharide / Marina Harper, John D. Boyce and Ben Adler -- Pasteurella multocida and Immune Cells / Katharina F. Kubatzky -- Molecular Biology of Pasteurella multocida Toxin / Joachim H. C. Orth and Klaus Aktories -- Pasteurella multocida Toxin Interaction with Host Cells: Entry and Cellular Effects / Brenda A. Wilson and Mengfei Ho -- Swine Atrophic Rhinitis Caused by Pasteurella multocida Toxin and Bordetella Dermonecrotic Toxin / Yasuhiko Horiguchi -- The Pasteurella multocida Toxin: A New Paradigm for the Link Between Bacterial Infection and Cancer / Alistair Lax.
- Pathogen derived immunomodulatory molecules 2009SpringerBacterial toxins as immunomodulators / David S. Donaldson and Neil A. Williams -- Innate immune evasion by staphylococci / Karin Ellen Veldkamp and Jos A.G. van Strijp -- Bacterial complement escape / Ilse Jongerius, Sanjay Ram, and Suzan Rooijakkers -- Modulation of innate immune signalling pathways by viral proteins / Orla Mulhern, Barry Harrington, and Andrew G. Bowie -- Viral TNF inhibitors as potential therapeutics / Masmudur M. Rahman, Alexandra R. Lucas, and Grant McFadden -- Lipoxins as an immune-escape mechanism / Fabiana S. Machado and Julio Aliberti -- Immunomodulatory activity and therapeutic potential of the filarial nematode secreted product, ES62 / William Harnett and Margaret M. Harnett -- Helminth-derived immunomodulatory molecules / Poom Adisakwattana ... [et al.] -- Fungal-derived immune modulating molecules / Tania C. Sorrell and Sharon C.A. Chen -- The immunosuppresive tick salivary protein, Salp15 / Ignacio J. Juncadella and Juan Anguita -- The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics / Alexandra Lucas ... [et al.] -- Helminthic therapy : using worms to treat immune-mediated disease / David E. Elliott and Joel V. Weinstock -- Chemokine binding proteins encoded by pathogens / Antonio Alcami and Margarida Saraiva.
- Pathogenic yeasts 2010Springer
- PCR detection of microbial pathogensSpringer Protocols
- Part 1. PCR Fundamentals -- Part 2. Clinical Aspects and Diagnosis of Infectious Disease -- Part 3. PCR Protocols for Bacterial Pathogens -- Part 4. PCR Protocols for Viral Pathogens -- Part 5. PCR Protocols for Fungal and Parasitic Pathogens -- Part 6. Susceptibility Screening.
- Peptide-based drug design 2008Springer ProtocolsPeptide-based drug design : here and now / Laszlo Otvos, Jr. -- Strategies for the discovery, isolation, and characterization of natural bioactive peptides from the immune system of invertebrates / Philippe Bulet -- Sequence analysis of antimicrobial peptides by tandem mass spectrometry / Christin Stegemann and Ralf Hoffmann -- The spot technique : synthesis and screening of peptide macroarrays on cellulose membranes / Dirk F.H. Winkler and William D. Campbell -- Analysis of A[beta] interactions using ProteinChip technology / Eleni Giannakis ... [et al.] -- NMR in peptide drug development / Jan-Christoph Westermann and David J. Craik -- Molecular dynamics simulations of peptides / Jeffrey Copps, Richard F. Murphy and Sandor Lovas -- Short linear cationic antimicrobial peptides : screening, optimizing, and prediction / Kai Hilpert, Christopher D. Fjell and Artem Cherkasov -- Investigating the mode of action of proline-rich antimicrobial peptides using a genetic approach : a tool to identify new bacterial targets amenable to the design of novel antibiotics / Marco Scocchi ... [et al.] -- Serum stability of peptides / Håvard Jenssen and Stein Ivar Aspmo -- Preparation of glycosylated amino acids suitable for Fmoc solid-phase assembly / Mare Cudic and Gayle D. Burstein -- Synthesis of O-phosphopeptides on solid phase / David Singer and Ralf Hoffmann -- Peptidomimetics : Fmoc solid-phase pseudopeptide synthesis / Predrag Cudic and Maciej Stawikowski -- Synthesis of toll-like receptor-2 targeting lipopeptides as self-adjuvanting vaccines / Brandon Y. Chua, Weiguang Zeng and David C. Jackson -- Synthesis of a multivalent, multiepitope vaccine construct / Laszlo Otvos, Jr. -- Cysteine-containing fusion tag for site-specific conjugation of therapeutic and imaging agents to targeting proteins / Marina V. Backer ... [et al.].
- Phosphoinositides and disease 2012SpringerLinkPhosphoinositides (PIs) are minor components of cellular membranes that play critical regulatory roles in several intracellular functions. This book describes the main enzymes regulating the turnover of each of the seven PIs in mammalian cells, some of their intracellular functions and some evidence of their involvement in human diseases. Due to the complex inter-relation between the distinct PIs and the plethora of functions that they can regulate inside a cell, this book is not meant to be a comprehensive coverage of all aspects of PIs signalling but rather an overview on the current state of the field and where it could go from here. Phosphoinositide and inositol phosphates interact with and modulate the recruitment and activation of key regulatory proteins and in doing so control diverse functions including cell growth and proliferation, apoptosis, cytoskeletal dynamics, insulin action, vesicle trafficking and nuclear function. Initially, inositide signaling was limited to the PLC pathway; however, it is now clear that all the seven phosphoinositides and more than 30 different inositol phosphates likely have specific signaling functions. Moreover there is a growing list of proteins that are regulated by inositol signaling. This has raised the question as to how inositol signaling can control diverse processes and yet maintain signaling specificity. Controlling the levels of inositol signaling molecules and their subcellular compartmentalisation is likely to be critical. This meeting will bring together scientists from different backgrounds to discuss how understanding inositol signaling may be used to target complex human diseases that manifest themselves when inositol signaling is deregulated.
- Recent Developments in the Molecular Taxonomy of Fungi / Roland W.S. Weber -- Sordaria macrospora, a Model System for Fungal Development / Ulrich Kück, Stefanie Pöggeler, Minou Nowrousian, Nicole Nolting and Ines Engh -- Inteins - Selfish Elements in Fungal Genomes / Skander Elleuche and Stefanie Pöggeler -- Apoptosis in Fungal Development and Ageing / Diana Brust, Andrea Hamann and Heinz D. Osiewacz -- Communication of Fungi on Individual, Species, Kingdom, and Above Kingdom Levels / Ursula Kües and Mónica Navarro-González -- Yeast Killer Toxins: Fundamentals and Applications / Friedhelm Meinhardt and Roland Klassen -- Evolutionary and Ecological Interactions of Mould and Insects / Marko Rohlfs, Monika Trienens, Ulrike Fohgrub and Frank Kempken -- Endophytic Fungi, Occurrence and Metabolites / Daniela Weber -- Fungal Origin of Ergoline Alkaloids Present in Dicotyledonous Plants (Convolvulaceae) / Eckhard Leistner and Ulrike Steiner -- Secondary Metabolites of Basidiomycetes / Anja Schüffler and Timm Anke -- Identification of Fungicide Targets in Pathogenic Fungi / Andrew J. Foster and Eckhard Thines -- Helminth Electron Transport Inhibitors Produced by Fungi / Rokuro Masuma, Kazuro Shiomi and Satoshi Ōmura -- Cyclic Peptides and Depsipeptides from Fungi / Heidrun Anke and Luis Antelo -- Fungal Genome Mining and Activation of Silent Gene Clusters / Axel A. Brakhage, Sebastian Bergmann, Julia Schuemann, Kirstin Scherlach and Volker Schroeckh, et al. -- Non-Ribosomal Peptide Synthetases of Fungi / Katrin Eisfeld -- Biosynthesis of Fungal Polyketides / Julia Schuemann and Christian Hertweck -- Physiological and Molecular Aspects of Ochratoxin A Biosynthesis / Rolf Geisen and Markus Schmidt-Heydt -- Genetic and Metabolic Engineering in Filamentous Fungi / Jochen Schmid, Ulf Stahl and Vera Meyer.
- Planctomycetes cell structure, origins and biology 2013SpringerHistory, classification and cultivation of the planctomycetes / Cheryl Jenkins and James T. Staley -- Cell compartmentalization and endocytosis in planctomycetes: structure and function in complex bacteria / John A. Fuerst, Richard I. Webb, and Evgeny Sagulenko -- Structural aspects of MC proteins of PVC superphylum members / Damien P. Devos -- Cell biology of anaerobic ammonium-oxidizing bacteria: unique prokaryotes with an energy-conserving intracellular compartment / Sarah Neumann, Muriel C.F. van Teeseling and Laura van Niftrik -- Acidophilic planctomycetes: expanding the horizons of new planctomycete diversity / Svetlana N. Dedysh and Irina S. Kulichevskaya -- Toward the development of genetic tools for Planctomycetes / Mareike Jogler and Christian Jogler -- Genomics and bioinformatics of the PVC superphylum / Olga K. Kamneva, Daniel H. Haft, Stormy J. Knight, Davide A. Liberles, and Naomi L. Ward -- Distribution and evolution of C1 transfer enzymes and evolution of the planctomycetes / Ludmila Chistoserdova -- Unusual members of the PVC superphylum: the methanotrophic Verrucomicrobia genus "Methylacidiphilum" / Christine E. Sharp, Huub J.M. Op den Camp, Ivica Tamas, and Peter F. Dunfield -- Phyla related to Planctomycetes: members of phylum Chlamydiae and their implications for Planctomycetes cell biology / Claire Bertelli and Gilbert Greub -- Planctomycetes: their evolutionary implications for models for origins of eukaryotes and the eukaryote nucleus and endomembranes / John A. Fuerst and Evgeny Sagulenko -- Final word: the future of planctomycetology and related studies / John A. Fuerst -- Index.
- Introduction / Joseph Seckbach, Aharon Oren, and Helga Stan-Lotter -- Foreword / Richard W. Castenholz -- Preface / Koki Horikoshi -- Editors' biographies -- List of authors and their addresses -- Polyextremophiles and the constraints for terrestrial habitability / M.C. Capece et al. -- Life on the edge and astrobiology : who is who in the polyextremophiles world? / J. Seckbach -- The dynamic genomes of acidophiles / F.J. López de Saro et al. -- Two centuries of microbiological research in the Wadi Natrun, Egypt : a model system for the study of the ecology, physiology, and taxonomy of haloalkaliphilic microorganisms / A. Oren -- Adaptation in haloalkaliphiles and natronophilic bacteria / H.L. Banciu and D.Y. Sorokin -- A random biogeochemical walk into three soda lakes of the western USA : with an introduction to a few of their microbial denizens / R.S. Oremland -- Halophilic, acidophilic, and haloacidophilic prokaryotes / H. Minegishi -- Life in magnesium- and calcium-rich hypersaline environments : salt stress by chaotropic ions / A. Oren -- Survival strategies of halophilic oligotrophic and desiccation resistant prokaryotes / H. Stan-Lotter and S. Fendrihan -- Radiation resistance in extremophiles : fending off multiple attacks / K.M. Webb and J. DiRuggiero -- Thermoalkaliphilic microbes / V. Kumar and T. Satyanarayana -- Acido- and thermophilic microorganisms : their features, and the identification of novel enzymes or pathways / Y. Kawarabayasi -- Microbial diversity in acidic high-temperature steam vents / R.L. Weiss Bizzoco and S.T. Kelley -- Left out in the cold : life in cryoenvironments / J. Goordial et al. -- Microbial diversity and enzymes in ikaite columns : a cold and alkaline environment in Greenland / J.K. Vester et al. -- Microbial communities thriving in various ice ecosystems / B. Sattler et al. -- Snow algae : adaptation strategies to survive on snow and ice / T. Leya -- Adaptation of Antarctic freshwater green algae to extreme environments / H. Hu -- Deep subsurface oil reservoirs as poly-extreme habitats for microbial life. A current review / A. Wentzel et al. -- Expanding limits for life to a new dimension : microbial growth at hypergravity / S. Deguchi and K. Horikoshi -- Microbial eukaryotes in marine oxygen minimum zones / W.D. Orsi and V.P. Edgcomb -- Deep hypersaline anoxic basins as model systems for environmental selection of microbial plankton / A. Stock et al. -- Microbial eukaryotes in hypersaline anoxic deep-sea basins / V.P. Edgcomb and W.D. Orsi -- Life at high salt and low oxygen : how do the Halobacteriaceae cope with low oxygen concentrations in their environment? / A. Oren -- Niches and adaptations of polyextremotolerant black fungi / M. Grube et al. -- Polyextremophilic photoautotrophic eukaryotic algae / W. Reisser -- Extremophilic magnetotactic bacteria / C.T. Lefèvre and D.A. Bazylinski -- Tardigrades : an example of multicellular extremophiles / D. Schulze-Makuch and J. Seckbach -- Polyextremophiles : summary and conclusions / J. Chela-Flores.
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