Books by Subject
- AccessMedicine Lange Case files — Foodborne microbial pathogens : mechanisms and pathogenesis (100)
- Food-borne pathogens : methods and protocols — Microbiology of waterborne diseases : microbiological aspects and risks. Second edition. [2nd ed.] (100)
- Microbiology of wounds — Systems biology in biotech & pharma : a changing paradigm (100)
- Systems biology of bacteria — Yeast systems biology : methods and protocols (30)
- Toy, Eugene C.Clinical cases selected from the LANGE Case Files series, edited by Eugene C. Toy, MD.
- Advanced quantitative microbiology for foods and biosystems : models for predicting growth and inactivation2006 CRCnetBASEMicha Peleg.
- 2006 Springer[edited by] Yi-Wei Tang, Charles W. Stratton.
- 2013 SpringerYi-Wei Tang, Charles W. Stratton, editors.
- 2014 SpringerVijay C. Verma, Alan C. Gange, editors.In recent years there has been significant attention paid on the endophytic research by various groups working within this domain. Mutualistic endophytic microbes with an emphasis on the relatively understudied fungal endophytes are the focus of this special book. Plants are associated with micro-organisms: endophytic bacteria and fungi, which live inter- and intra-cellularly without inducing pathogenic symptoms, but have active biochemical and genetic interactions with their host. Endophytes play vital roles as plant growth promoters, biocontrol agents, biosurfactant producers, enzymes and secondary metabolite producers, as well as providing a new hidden repertoire of bioactive natural products with uses in pharmaceutical, agrochemical and other biotechnological applications. The increasing interest in endophytic research generates significant progress in our understanding of the host-endophyte relationship at molecular and genetic level. The bio-prospection of microbial endophytes has led to exciting possibilities for their biotechnological application as biocontrol agent, bioactive metabolites, and other useful traits. Apart from these virtues, the microbial endophytes may be adapted to the complex metabolism of many desired molecules that can be of significant industrial applications. These microbes can be a useful alternative for sustainable solutions for ecological control of pests and diseases, and can reduce the burden of excess of chemical fertilizers for this purpose. This book is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.
- 2006 Springeredited by A. D. Hocking, J.I. Pitt, R.A. Samson and U. Thrane.Section 1. Understanding the fungi producing important mycotoxins -- Section 2. Media and method development in food mycology -- Section 3. Physiology and ecology of mycotoxigenic fungi -- Section 4. Control of fungi and mycotoxins in foods.
- v.1-2=, 2016 Springerv.2, 2016 SpringerGianfranco Donelli, editor.Imported and indigenous cases of invasive meningococcal disease W:P1.5,2:F1-1:ST-11: the migration link. Italy, June-November 2014, Paola Stefanelli*, Cecilia Fazio, Arianna Neri, Giovanni Rezza, Santino Severoni, Paola Vacca, Teresa Fasciana, Alessandro Bisbano, Francesca Di Bernardo and Anna Giammanco -- Partial protection induced by 2011-2012 influenza vaccine against serologically evidenced A(H3N2) influenza virus infections in elderly institutionalized people, Barbara Camilloni, Michela Basileo, Giuseppe Menculini, Paolo Tozzi, Anna Maria Iorio* -- Fungal occurrence in the hair and skin of symptomatic pets in Turin, Italy, Valeria Allizond, Vivian Tullio, Anna Maria Cuffini*, Janira Roana, Daniela Scalas, Elisa Simona Marra, Giorgia Piersigilli, Narcisa Mandras, Giuliana Banche -- Infectious agents associated with head and neck carcinomas, Andrea Hettmann, Anett Demcsák, Gábor Decsi, Ádám Bach, Dóra Pálinkó,László Rovó, Katalin Nagy, Mária Takács, Janos Minarovits* -- Increase in peripheral CD3-CD56brightCD16- natural killer cells in Hashimoto's thyroiditis associated with HHV-6 infection, Roberta Rizzo*, Maria Chiara Zatelli, Antonella Rotola, Enzo Cassai, Ettore Degli Uberti, Dario Di Luca, Elisabetta Caselli -- In vitro and in vivo biofilm wound models and their application -- Gilles Brackman* and Tom Coenye -- The Lactobacillus plantarum Eno A1 enolase is involved in immunostimulation of Caco-2 cells and in biofilm development, Valeria Vastano, Annunziata Pagano, Alessandra Fusco, Gianluca Merola, Margherita Sacco, Giovanna Donnarumma* -- Role of sonication in the microbiological diagnosis of implant-associated infections: beyond the orthopedic prosthesis, Oliva A, Pavone P, D'Abramo A, Iannetta M, Mastroianni CM, Vullo V -- The isolation, identification and analyses of Lactobacillus genus bacteria with probiotic potential, Tatiana A. Cherdyntseva, Irina B. Kotova and Alexander I. Netrusov -- In vitro activity of tigecycline against Acinetobacter baumannii: Global epidemiology and resistance mechanisms -- Spyros Pournaras, Vasiliki Koumaki, Vasiliki Gennimata, Evangelia Kouskouni, and AthanassiosTsakris.Also available: Print – v. 1-2=, 2016
- 2012 SpringerRussell H. Vreeland, editor.Approaches toward the study of halophilic microorganisms in their natural environments : who are they and what are they doing? / Aharon Oren -- Media and conditions for the growth of halophilic and halolerant bacteria and ardchaea / Mark A. Schneegurt -- Taxonomy of halophilic archaea and bacteria / Antonio Ventosa ... [et al.] -- Halophilic viruses / Shereen Sabet -- Microorganisms in evaporites : review of modern geomicrobiology / Tim K. Lowenstein -- Searching for microbes and DNA in ancient halite / Russell H. Vreeland -- DNA replication and repair in halophiles / Adrienne Kish and Jocelyne DiRuggiero -- Gene transfer mechanisms, population genetics/genimics and the evolution of haloarchaea / R. Thane Papke and Scott Chimileski -- Worth your salt : halophiles in education / Bonnie K. Baxter, Jaimi K. Butler and Betsy Kleba -- Halophiles in the public media / Russell H. Vreeland.
- 2012 SpringerAlzira Maria Paiva de Almeida, Nilma Cintra Leal, editors.Also available: Print – 2012
- 2016 SpringerJürgen Harder, Jens-M. Schröder, editors.Antimicrobial peptides in cutaneous wound healing -- Antimicrobial peptides as endogenous antibacterials and antivirals at the ocular surface -- Function of antimicrobial peptides in lung innate immunity -- Role of antimicrobial peptides to prevent infections in the kidney and urinary tract -- Antimicrobial peptides in the gut -- Metal sequestration: An important contribution of antimicrobial peptides to nutritional immunity -- Regulation of antimicrobial peptide gene expression by vitamin D -- Dichotomous roles of cationic polypeptides targeting HIV -- Antimicrobial peptides in host-defense: functions beyond antimicrobial activity.
- 2006 SpringerW.M. Shafer (ed.).Paneth cell [alpha]-defensin synthesis and function / A.J. Ouellette -- Immunomodulatory properties of defensins and cathelicidins / D.M.E. Bowdish, D.J. Davidson, and R.E.W. Hancock -- Host antimicrobial defence peptides in human disease / B. Agerberth and G.H. Guðmundsson -- Antimicrobial peptides: an essential component of the skin defensive barrier / M.H. Braff and R.L. Gallo -- Antimicrobial peptides versus invasive infections / M.R. Yeaman and A.S. Bayer -- Antimicrobial peptides in the airway / D.M. Laube ... [et al.] -- Hepcidin: a peptide hormone at the interface of innate immunity and iron metabolism / T. Ganz -- Innate host defense of human vaginal and cervical mucosae / A.M. Cole -- Molecular mechanisms of bacterial resistance to antimicrobial peptides / D. Kraus and A. Peschel -- Bacterial evasion of antimicrobial peptides by biofilm formation / M. Otto.
- 2013 Springeredited by Pieter S. Hiemstra, Sebastian A.J. Zaat.Evolution of Antimicrobial Peptides: A View from the Cystine Chapel -- Innate Immunity in Plants: The Role of Antimicrobial Peptides -- Antimicrobial Peptides Produced by Microorganisms -- LL-37: An Immunomodulatory Antimicrobial Host Defence Peptide -- Wound Repair and Antimicrobial Peptides -- WAPing Out Pathogens and Disease in the Mucosa: Roles for SLPI and Trappin-2 -- Histatins: Multifunctional Salivary Antimicrobial Peptides -- Structure-Function Relationships of Antimicrobial Chemokines -- Mechanisms and Significance of Bacterial Resistance to Human Cationic Antimicrobial Peptides -- Antimicrobial Peptides and Inflammatory Bowel Disease -- Cystic Fibrosis and Defective Airway Innate Immunity -- Antimicrobial Peptides in Chronic Obstructive Pulmonary Disease -- Host Defense Peptides: Immune Modulation and Antimicrobial Activity In Vivo -- Helping the Host: Induction of Antimicrobial Peptides as a Novel Therapeutic Strategy Against Infections.Also available: Print – 2013
- 2014 WHOWorld Health Organization.This report examines, for the first time, the current status of surveillance and information on antimicrobial resistance (AMR) at country level worldwide, with particularly attention to antibacterial resistance.Also available: Print – 2014
- 2015 ScienceDirecteditors, Chin-Yi Chen, Xianghe Yan, Charlene R. Jackson.1. Introduction to antimicrobial-resistant foodborne pathogens / Patrick Butaye, Maria Angeles Argudín and John Threlfall -- 2. Antimicrobial resistance of Shiga toxin-producing Escherichia coli / Jinru Chen -- 3. Antibiotic resistance in pathogenic Salmonella / Steven C. Ricke and Juliany Rivera Calo -- 4. Antimicrobial resistance and Campylobacter jejuni and C. coli / Mirko Rossi, Satu Olkkola, Mati Roasto, Rauni Kivistö and Marja-Liisa-Hänninen -- 5. Antimicrobial resistance in Yersinia enterocolitica / Anna Fabrega, Clara Ballesté-Delpierre and Jordi Vila -- 6. Antimicrobial resistance in Vibrio species / Craig Baker-Austin -- 7. Antimicrobial resistance in Shigella species / Keith A. Lampel -- 8. Antimicrobial resistance in Listeria spp. / Nathan A. Jarvis, Philip G. Crandall, Corliss A. O'Bryan and Steven C. Ricke -- 9. Antibiotic resistance in Enterococci : a food safety perspective / Anuradha Ghosh and Ludek Zurek -- 10. Clostridium difficile: a food safety concern? / Jane W. Marsh and Lee H. Harrison -- 11. Methods for the detection of antimicrobial resistance and the characterization of Staphylococcus aureus isolates from food-producing animals and food of animal origin / Kristina Kadlec, Sarah Wendlandt, Andrea T. Fessler and Stefan Schwarz -- 12. Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae / Agnese Lupo, Krisztina M. Papp-Wallace, Robert A. Bonomo and Andrea Endimiani -- 13. Monitoring and surveillance : the national antimicrobial resistance monitoring system / Emily Crarey, Claudine Kabera and Heather Tate -- 14. Risk assessment of antimicrobial resistance / H. Gregg Claycamp -- 15. Food microbial safety and animal antibiotics / Louis Anthony (Tony) Cox -- 16. Antibiotic-resistant bacteria and resistance genes in the water-food nexus of the agricultural environment / Pei-Ying Hong -- 17. Development and application of novel antimicrobials in food and food processing / Yangjin Jung and Karl R. Matthews -- 18. Database resources dedicated to antimicrobial peptides / Guangshun Wang -- 19. Metabolic network analysis-based identification of antimicrobial drug target in pathogenic bacteria / Vinayak Kapatral -- 20. Application of metagenomic technologies for antimicrobial resistance and food safety research and beyond / Chin-Yi Chen, Xianghe Yan, Siyun Wang and Charlene R. Jackson.
- 2006 ScienceDirectedited by Dilip K. Arora, Randy M. Berka, Gautam B. Singh.The advances in genomic technologies, such as microarrays and high throughput sequencing, have expanded the realm of possibilities for capturing data and analyzing it using automated computer driven bioinformatics tools. With the completion of the sequencing of genomes of human and several model organisms, a quest for scientific discoveries being fueled by integrative and multidimensional techniques in mathematics and computational sciences. In this volume, leading researchers and experts have provided an overview of significant concepts from biological, mathematical, and computational perspectives. It provides a high level view of fungal genomic data integration and annotation, classification of proteins and identification of vaccine targets, identification of secretome or secreted proteins in fungal genomes, as well as tools for analyzing microarray expression profiles. * Provides a survey of theoretical underpinnings on the technological tools and applications * Discusses the tools utilized for the annotation of fungal genomes and addresses issues related to automated annotation generation in a high throughput biotechnology environment * describing the applications of the concepts and methodologies presented throughout the book.
- 2012Audrie Lin.Overview: 555 million preschool children live in developing countries where malnutrition (undernutrition) is a significant problem. The factors that contribute to this issue are multiple, with two important factors being gut microbiota and gut function. To begin to understand gut microbiota and gut function in a developing country, we performed two parallel studies: in the first study, we characterized the baseline gut microbiota of healthy Bangladeshi children, and in the second study, we investigated the association between household environmental conditions and gut function in Bangladeshi children. The gut microbiota affect nutrient metabolism, immune function, and pathogen resistance. Loss of gut function as occurs in environmental enteropathy (a multifaceted, subclinical intestinal disorder likely derived from repeated episodes of infectious gastroenteritis and chronic inflammation) contributes to malnutrition and growth faltering. It is possible that these processes are interrelated with the gut microbiota serving a critical role in environmental enteropathy. Gut microbiota: Previous studies have focused on the gut microbiota of infants and adults from developed countries, but few have characterized the gut microbiota of people living in developing countries. Furthermore, little is known about the gut microbiota and its variation over time in primary-school-age children and adolescents in either developed or developing countries. In this study, we compared the monthly variation in fecal microbiota composition of healthy children (ages 8--14 years) living in an urban slum in Bangladesh with that of age-matched children from affluent suburban communities in the United States. We analyzed 8,000 near full-length sequences of the small-subunit ribosomal RNA gene (16S rDNA) and over 845,000 pyrosequencing reads spanning the V1-V3 variable region of the 16S rDNA. The distal gut of Bangladeshi children harbored significantly higher microbial diversity than U.S. children, a result validated by the discovery of several novel lineages from various bacterial phyla in the full-length Bangladeshi dataset. Bangladeshi and U.S. children displayed distinct gut microbiota architectures. Moreover, significantly lower month-to-month temporal stability was observed in Bangladeshi children compared to U.S. children. Together, these results suggest that different environmental or genetic variables may affect the microbiota of healthy children in the two countries. Further studies are necessary to investigate the underlying mechanisms of these differences and to incorporate these insights into prevention or treatment of diseases. Gut function: Although poor water quality, sanitation, and hygiene are putative risk factors for environmental enteropathy, there are no studies investigating the relationship of household environmental conditions to environmental enteropathy. We compared levels of environmental enteropathy markers to growth patterns and measured the prevalence of parasitic infections in children living in different levels of environmental cleanliness based on indictors of water, sanitation, and hygiene in their households. We conducted a follow-up study of 119 children (< 4 years old) from an existing cohort, living in rural Bangladesh and divided into two types of households: a 'mitigated household' had good water quality, improved sanitation, and a handwashing station stocked with water and soap, and a 'contaminated household' had poor water quality, and inadequate sanitation and handwashing facilities. We measured anthropometry, intestinal parasitic infection, and the following markers to assess gut function: Lactulose:Mannitol (L:M) ratio, immunoglobulin G endotoxin core antibody (IgG EndoCAb), and total IgG. After adjustment for potential confounding, children from mitigated households had higher height-for-age Z-scores (HAZ), lower L:M ratios, and lower IgG EndoCAb titers than children from contaminated households. The L:M ratio was also strongly associated with HAZ in the cohort. Children living in environmentally mitigated households had lower levels of parasitic infection, improved measures of gut function, and improved growth compared to children living in contaminated environments. These results support the hypothesis that environmental contamination mediated through environmental enteropathy could be a cause of growth faltering in low-income countries. Interpretation: By characterizing the baseline gut microbiota of healthy children living in a developing country and correlating their gut function with household environmental conditions, our work provides a foundation to address the role of the gut microbiota and environmental enteropathy in child health.
- 2007 Springeredited by Claudine Elmerich and William E. Newton.
- 2013 SpringerStacey Schultz-Cherry, editor.Since their initial discovery in the 1970's, astroviruses have been recognized as a leading cause of enteritis in infants, the elderly, and immunocompromised people, and were known to be widespread in animals and birds. In recent years, and with the advent of pyrosequencing, there has been a virtual explosion in the number of newly identified astrovirus genotypes. With this has come an increased understanding in astrovirus biology, structure, epidemiology, immunology, and disease pathogenesis including the likelihood of extraintestinal and systemic infections. The advent of new diagnostic tests that detect all of the currently identify human astrovirus strains may prove that these viruses are more prevalent in populations than currently realized.This book will provide state-of-the-art information on our current understanding of astroviruses for researchers, medical and veterinary providers, and diagnosticians as prepared by the leaders in the respective fields. The goal is to bring the reader up to date on the state of knowledge on this constantly evolving and exciting field of virology.
- 2016 SpringerTomohiro Kurosaki, Jürgen Wienands, editors.Assembly and function of the precursor B-cell receptor -- Receptor Dissociation and B cell activation -- Molecular mechanisms of B cell antigen gathering and endocytosis -- BTK signaling in B cell differentiation and autoimmunity -- The memory function of the B cell antigen receptor -- PI3K signaling in normal B cells and chronic lymphocytic leukemia (CLL) -- Role of Calcium Signaling in B Cell Activation and Biolog -- Roles of the NF-kappaB pathway in B-lymphocyte biology -- MAP kinase cascades in antigen receptor signaling and physiology.
- 2011 SpringerDirk Linke, Adrian Goldman, editors.Adhesins of Human Pathogens from the Genus Yersinia / Jack C. Leo and Mikael Skurnik -- Adhesive Mechanisms of Salmonella enterica / Carolin Wagner and Michael Hensel -- Adhesion Mechanisms of Borrelia burgdorferi / Styliani Antonara, Laura Ristow and Jenifer Coburn -- Adhesins of Bartonella spp. / Fiona O'Rourke, Thomas Schmidgen, Patrick O. Kaiser, Dirk Linke and Volkhard A.J. Kempf -- Adhesion Mechanisms of Plant-Pathogenic Xanthomonadaceae / Nadia Mhedbi-Hajri, Marie-Agnès Jacques and Ralf Koebnik -- Adhesion by Pathogenic Corynebacteria / Elizabeth A. Rogers, Asis Das and Hung Ton-That -- Adhesion Mechanisms of Staphylococci / Christine Heilmann -- Protein Folding in Bacterial Adhesion: Secretion and Folding of Classical Monomeric Autotransporters / Peter van Ulsen -- Structure and Biology of Trimeric Autotransporter Adhesins / Andrzej Łyskowski, Jack C. Leo and Adrian Goldman -- Crystallography and Electron Microscopy of Chaperone / Usher Pilus Systems / Sebastian Geibel and Gabriel Waksman -- Crystallography of Gram-Positive Bacterial Adhesins / Vengadesan Krishnan and Sthanam V. L. Narayana -- The Nonideal Coiled Coil of M Protein and Its Multifarious Functions in Pathogenesis / Partho Ghosh -- Bacterial Extracellular Polysaccharides / Kateryna Bazaka, Russell J. Crawford, Evgeny L. Nazarenko and Elena P. Ivanova -- Carbohydrate Mediated Bacterial Adhesion / Roland J. Pieters -- The Application of NMR Techniques to Bacterial Adhesins / Frank Shewmaker -- Electron Microscopy Techniques to Study Bacterial Adhesion / Iwan Grin, Heinz Schwarz and Dirk Linke -- EM Reconstruction of Adhesins: Future Prospects / Ferlenghi Ilaria and Fabiola Giusti -- Atomic Force Microscopy to Study Intermolecular Forces and Bonds Associated with Bacteria / Steven K. Lower -- Assessing Bacterial Adhesion on an Individual Adhesin and Single Pili Level Using Optical Tweezers / Ove Axner, Magnus Andersson, Oscar Björnham, Mickaël Castelain and Jeanna Klinth, et al. -- Short Time-Scale Bacterial Adhesion Dynamics / Jing Geng and Nelly Henry -- Deciphering Biofilm Structure and Reactivity by Multiscale Time-Resolved Fluorescence Analysis / Arnaud Bridier, Ekaterina Tischenko, Florence Dubois-Brissonnet, Jean-Marie Herry and Vincent Thomas, et al. -- Inhibition of Bacterial Adhesion on Medical Devices / Lígia R. Rodrigues.Also available: Print – 2011
- 2008 SpringerTony Romeo, editor.Also available: Print – 2008
- 2013 Springer Protocolsedited by Anne H. Delcour.Bird's eye view of the bacterial landscape / Natividad Ruiz -- Visualizing the bacterial cell surface : an overview / Harald Engelhardt -- Purification of the outer membrane usher protein and periplasmic chaperone-subunit complexes from the P and type 1 pilus systems / Nadine S. Henderson and David G. Thanassi -- Experimental manipulation of the microbial functional amyloid called curli / Yizhou Zhou [and others] -- Visualization of gram-positive bacterial pili / Chungyu Chang [and others] -- Single cell microfluidic studies of bacterial motility / Adrien Ducret, Olivier Theodoly, and Tam Mignot -- Chromatographic analysis of the Escherichia coli polysialic acid capsule / Susan M. Steenbergen and Eric R. Vimr -- Analysis of exopolysaccharides in Myxococcus xanthus using confocal laser scanning microscopy / Wei Hu, Renate Lux, and Wenyuan Shi -- Assessment of multidrug efflux assemblies by surface plasmon resonance / Elena B. Tikhonova and Helen I. Zgurskaya -- Fluorescence microscopy and proteomics to investigate subcellular localization, assembly, and function of the type II secretion system / Tanya L. Johnson [and others] -- Pore formation by T3SS translocators : liposome leakage assay / Eric Faudry, Caroline Perdu, and Ina Attree -- Isolation of bacterial type IV machine subassemblies / Mayukh K. Sarkar [and others] -- Production and crystallization of bacterial type V secretion proteins / Hye-Jeong Yeo -- Assembly of bacterial outer membrane proteins / Jan Grijpstra, Martine P. Bos, and Jan Tommassen -- Outer membrane of gram-negative bacteria : lipid A isolation and characterization / Jessica V. Hankins [and others] -- Quantitative and qualitative preparations of bacterial outer membrane vesicles / Halima Chutkan [and others] -- In vitro peptidoglycan synthesis assay with lipid II substrate / Jacob Biboy, Nhat Khai Bui, and Waldemar Vollmer -- Extraction of cell wall-bound teichoic acids and surface proteins from Listeria monocytogenes / Filipe Carvalho [and others] -- Subfractionation and analysis of the cell envelope (lipo) polysaccharides of Mycobacterium tuberculosis / Anna E. Grzegorzewicz and Mary Jackson -- Protein disulfide bond formation in the periplasm : determination / Katleen Denoncin [and others] -- Using reporter genes and the Escherichia coli ASKA overexpression library in screens for regulators of the gram negative envelope stress response / Julia L. Wong, Stefanie L. Vogt, and Tracy L. Raivio -- Isolation of bacteria envelope proteins / Shu Quan [and others] -- Patch clamp electrophysiology for the study of bacterial ion channels in giant spheroplasts of E. coli / Boris Martinac [and others] -- Electrophysiological characterization of bacterial pore-forming proteins in planar lipid bilayers / Owen S. Mapingire, Beau Wager, and Anne H. Delcour.
- 2010 SpringerRemus T. Dame, Charles J. Dorman, editors.
- 2012 Springer Protocolsedited by Jacques van Helden and Ariane Toussaint, Denis Thieffry.Bacterial molecular networks : bridging the gap between functional genomics and dynamical modelling / Jacques van Helden, Ariane Toussaint, and Denis Thieffry -- Bacterial interactomes : from interactions to networks / Emmanuelle Bouveret and Christine Brun -- From bacterial to microbial ecosystems (metagenomics) / Shannon J. Williamson and Shibu Yooseph -- Prokaryote genome fluidity : toward a system approach of the mobilome / Ariane Toussaint and Mick Chandler -- Reticulate classification of mosaic microbial genomes using NeAT website / Gipsi Lima-Mendez -- From metabolic reactions to networks and pathways / Masanori Arita -- Predicting metabolic pathways by sub-network extraction / Karoline Faust and Jacques van Helden -- Directed module detection in a large-scale expression compendium / Qiang Fu [and others] -- Using phylogenetic profiles to predict functional relationships / Matteo Pellegrini -- Extracting regulatory networks of Escherichia coli from RegulonDB / Heladia Salgado [and others] -- Browsing metabolic and regulatory networks with BioCyc / Mario Latendresse, Suzanne Paley, and Peter D. Karp -- Algorithms for systematic identification of small subgraphs / Joseph Geraci, Geoffrey Liu, and Igor Jurisica -- The degree distribution of ntworks : statistical model selection / William P. Kelly, Piers J. Ingram, and Michael P.H. Stumpf -- MAVisto : a tool for biological network motif analysis / Henning Schwöbbermeyer and Röbbe Wünschiers -- Using MCL to extract clusters from networks / Stijn van Dongen and Cei Abreu-Goodger -- Protein complex prediction with RNSC / Andrew D. King, Nataša Pržulj, and Igor Jurisica -- Network analysis and protein function prediction with the PRODISTIN web site / Anaïs Baudot, Ouissem Souiai, and Christine Brun -- Using NeAT Toolbox to compare networks to networks, clusters to clusters, and network to clusters / Sylvain Brohée -- Analyzing biological data using R : methods for graphs and networks / Nolwenn Le Meur and Robert Gentleman -- Detecting structural invariants in biological reaction networks / Jörn Behre [and others] -- Petri nets in Snoopy : a unifying framework for the graphical display, computational modelling, and simulation of bacterial regulatory networks / Wolfgang Marwan, Christian Rohr, and Monika Heiner -- Genetic Network Analyzer : a tool for the qualitative modeling and simulation of bacterial regulatory networks / Grégory Batt [and others] -- Logical modelling of gene regulatory networks with GINsim / Claudine Chaouiya, Aurélien Naldi, and Denis Thieffry -- Modelling the evolution of mutualistic symbioses / Maren L. Friesen and Emily I. Jones -- Modelling the onset of virulence in pthogenic bacteria / Wilfred D. Kepseu [and others] -- Spatial and stochastic cellular modeling with the Smoldyn Simulator / Steven S. Andrews.
- 2015 Springer Protocolsedited by Alessio Mengoni, Marco Galardini, Marco Fondi.Pulsed field gel electrophoresis and genome size estimates/ Rosa Alduina and Annalisa Pisciotta -- Comparative analyses of extrachromosomal bacterial replicons, identification of chromids, and experimental evaluation of their indispensability / Lukasz Dziewit and Dariusz Bartosik -- Choice of next-generation sequencing pipelines / F. Del Chierico ... [et al.] -- Pyrosequencing protocol for bacterial genomes / Ermanno Rizzi -- Bacterial metabarcoding by 16S rRNA gene ion torrent amplicon sequencing / Elio Fantini ... [et al.] -- Illumina-solexa sequencing protocol for bacterial genomes / Zhenfei Hu, Lei Cheng, and Hai Wang -- High-throughput phenomics / Carlo Viti ... [et al.] -- Comparative analysis of gene expression : uncovering expression conservation and divergence between Salmonella enterica serovar typhimurium strains LT2 and 14028S / Paolo Sonego ... [et al.] -- Raw sequence data and quality control / Giovanni Bacci -- Methods for assembling reads and producing contigs / Valerio Orlandini, Marco Fondi, and Renato Fani -- Mapping contigs using CONTIGuator / Marco Galardini, Alessio Mengoni, and Marco Bazzicalupo -- Gene calling and bacterial genome annotation with BG7 / Raquel Tobes ... [et al.] -- Defining orthologs and pangenome size metrics / Emanuele Bosi, Renato Fani, and Marco Fondi -- Robust identification of orthologues and paralogues for microbial pan-genomics using GET HOMOLOGUES : a case study of pIncA/C plasmids / Pablo Vinuesa and Bruno Contreras-Moreira -- Genome-scale metabolic network reconstruction / Marco Fondi and Pietro Liò -- From pangenome to panphenome and back / Marco Galardini, Alessio Mengoni, and Stefano Mocali -- Genome-wide detection of selection and other evolutionary forces / Zhuofei Xu and Rui Zhou -- Integrated microbial genome resource of analysis / Alice Checcucci and Alessio Mengoni.
- 2009 Kargervolume editors, Mattias Collin, Raymond Schuch.Chemical interactions between organisms in microbial communities / Duan, K. ... [et al.] -- Autoinducer-2-based chemical communication in bacteria : complexities of interspecies signaling / Federle, M.J. -- The molecular basis of excitation and adaptation during chemotactic sensory transduction in bacteria / Rao, C.V., Ordal, G.W. -- Bacterial PEP-dependent carbohydrate : phosphotransferase systems couple sensing and global control mechanisms / Lengeler, J.W., Jahreis, K.-- Correlations between carbon metabolism and virulence in bacteria / Poncet, S. ... [et al.] -- Stand-alone response regulators controlling global virulence networks in streptococcus pyogenes / McIver, K.S. -- The heme sensor system of staphylococcus aureus / Stauff, D.L., Skaar, E.P. -- Bacterial sensing of antimicrobial peptides / Otto, M. -- RNA thermosensors in bacterial pathogens / Johansson, J. -- Prevailing concepts of c-di-GMP signaling / Römling, U., Simm, R. -- Magnetosomes and magneto-aerotaxis / Frankel, R.B., Bazylinski, D.A. -- Engineering bacterial signals and sensors / Salis, H., Tamsir, A., Voigt, C.Also available: Print – 2009
- 2015 Springer Protocolsedited by Irina Artsimovitch, Thomas J. Santangelo.Mapping the Escherichia coli transcription elongation complex with exonuclease III / Zhaokun Liu and Irina Artsimovitch -- Purification of bacterial RNA polymerase : tools and protocols / Vladimir Svetlov and Irina Artsimovitch -- Monitoring translocation of multisubunit RNA polymerase along the DNA with fluorescent base analogues / Anssi M. Malinen, Matti Turtola, and Georgiy A. Belogurov -- In vitro and in vivo methodologies for studying the sigma-54-dependent transcription / Martin Buck [and nine others] -- Methods for the assembly and analysis of in vitro transcription-coupled-to-translation systems / Daniel Castro-Roa and Nikolay Zenkin -- Site-specific incorporation of probes into RNA polymerase by unnatural-amino-acid mutagenesis and Straudinger-Bertozzi ligation / Anirban Chakraborty [and seven others] -- Reconstruction of factor-dependent, promotor proximal pausing in Drosophila nuclear extracts / Jian Li and David S. Gilmour -- Direct competition assay for transcription fidelity / Lucyna Lubkowska and Maria L. Kireeva -- Single-stranded DNA aptamers for functional probing of bacterial RNA polymerase / Danil Pupov and Andrey Kulbachinskiy -- Biochemical analysis of transcription termination by RNA polymerase III from yeast Saccharomyces cerevisiae / Aneeshkumar G. Arimbasseri and Richard J. Maraia -- Use of RNA polymerase molecular beacon assay to measure RNA polymerase interactions with model promotor fragments / Vladimir Mekler and Konstantin Severinov -- Preparation of cDNA libraries for high-throughput RNA sequencing analysis of RNA 5' ends / Irina O. Vvedenskaya, Seth R. Goldman, and Bryce E. Nickels -- In situ footprinting of E. coli transcription elongation complex with chloroacetaldehyde / A. Rachid Rahmouni and Christine Mosrin-Hauman -- Using solutes and kinetics to probe large conformational changes in the steps of transcription initiation / Emily F. Ruff, Wayne S. Kontur, and M. Thomas Record Jr. -- Manipulating archaeal systems to permit analyses of transcription elongation-termination decisions in vitro / Alexandra M. Gehring and Thomas J. Santangelo -- Purification of active RNA polymerase I from yeast / Francis Dean Appling and David Alan Schneider -- Transcription in archaea : preparation of Methanocaldococcus jannaschii transcription machinery / Katherine Smollet, Fabian Blombach, and Finn Werner -- Transcription in archaea ; in vitro transcription assays for mjRNAP / Katherine Smollet, Fabian Blombach, and Finn Werner -- Experimental analysis of hFACT action during pol II transcription in vitro / Fu-Kai Hsieh, Olga I. Kulaeva, and Vasily M. Studitsky -- ChIP-Seq for genome-scale analysis of bacterial DNA-binding proteins / Richard P. Bonocora and Joseph T. Wade.
- 2007 SpringerM.A. Riley, M.A. Chavan (eds.).
- v. 1-2, 2009 Springer Protocolsv. 2, 2009 Springer Protocolsedited by Martha R.J. Clokie and Andrew M. Kropinski.v. 1. Isolation, characterization, and interactions -- v. 2. Molecular and applied aspects.
- v. 2a-2c, 2005. Springerv. 2b 2005 Springerv. 2c 2005 SpringerDavid R. Boone, Richard W. Castenholz, editors , volume one ; George M. Garrity, editor-in-chief ; editorial board, James T. Staley ... [et al.].v. 1. The Archaea and the deeply branching and phototrophic bacteria -- v. 2. The Proteobacteria: part A. Introductory essays; part B. The Gammaproteobacteria; part C. The Alpha-, beta-, delta-, and epsilonproteobacteria -- v. 3. The Firmicutes -- v. 4. The Bacteroidetes, Spirochaetes, Tenericutes (Mollicutes), Acidobacteria, Fibrobacteres, Fusobacteria, Dictyoglomi, Gemmatimonadetes, Lentisphaerae, Verrucomicrobia, Chlamydiae, and Planctomycetes -- v. 5. The Actinobacteria.Also available: Print – v. 1-5, 2001-12.
- 2015 Wileysupervising editor, William B. Whitman ; editors, Paul DeVos, Jonsik Chun, Sveltlana Dedysh, Brian Hedlund, Peter Kämpfer, Fred Rainey, Martha Trujillo.
- 2013 SpringerUlrich Dobrindt, Jörg H. Hacker, Catharina Svanborg, editors.E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity / Andreas Leimbach, Jörg Hacker, Ulrich Dobrindt -- What Distinguishes Highly Pathogenic Staphylococci from Medium- and Non-pathogenic? / Ralf Rosenstein, Friedrich Götz -- Microevolution of Pseudomonas aeruginosa to a Chronic Pathogen of the Cystic Fibrosis Lung / Michael Hogardt, Jürgen Heesemann -- Lactobacillus: Host-Microbe Relationships / John O'Callaghan, Paul W. O'Toole -- Bacterial Moonlighting Proteins and Bacterial Virulence / Brian Henderson, Andrew Martin -- Symbionts and Pathogens: What is the Difference? / Vicente Pérez-Brocal, Amparo Latorre, Andrés Moya -- Ecology and Physiology of the Intestinal Tract / Michael Blaut -- The Gut Microflora and Its Variety of Roles in Health and Disease / Julia-Stefanie Frick, Ingo B. Autenrieth -- Host-Recognition of Pathogens and Commensals in the Mammalian Intestine / Oriana Rossi, Peter van Baarlen, Jerry M. Wells -- Contribution of the Intestinal Microbiota to Human Health: From Birth to 100 Years of Age / Jing Cheng, Airi M. Palva, Willem M. de Vos.
- 2007 Springervolume author, J. William Costerton.
- 2006 CRCnetBASEedited by John L. Pace, Mark E. Rupp, and Roger G. Finch.Microbial biofilms / Xiuping Jiang and John L. Pace -- Economic impact of biofilms on treatment costs / John G. Thomas, Isaiah Litton, and Harald Rinde -- Biofilm-related indwelling medical device infections / Matthew K. Schinabeck and Mahmoud A. Ghannoum -- Medical device composition and biological secretion influences on biofilm formation / Sean P. Gorman and David S. Jones -- Role of biofilms in infections caused by Escherichia coli / Grégory Jubelin, Corinne Dorel, and Philippe Lejeune -- Staphylococcus aureus biofilms / Julie M. Higashi and Paul M. Sullam -- Coagulase-negative staphylococci / Dietrich Mach ... [et al.] -- Pseudomonas aeruginosa biofilm infections in cystic fibrosis / Andrea Smiley and Daniel J. Hassett -- Candida / Stephen Hawser and Khalid Islam -- Current perspectives on the regulation of the ica operon and biofilm formation in Staphylococcus epidermidis / Paul D. Fey and Luke D. Handke -- Cell-to-cell communication in bacteria / Kenneth D. Tucker and Luciano Passador -- Persisters: specialized cells responsible for biofilm tolerance to antimicrobial agents / Kim Lewis ... [et al.] -- Minimal biofilm eradication concentration (MBEC) assay: susceptibility testing for biofilms / Howard Ceri ... [et al.] -- Environmental cues regulate virulence and biofilm formation / John L. Pace and Steven M. Frey -- In vivo models for the study of biomaterial-associated infection by biofilm-forming staphylococci / Luke D. Handke and Mark E. Rupp -- Host response to biofilms / Susan Meier-Davis -- Pharmacodynamics and the treatment of IMD-related infections / Roger Finch and Sarah Gander -- Protein synthesis inhibitors, fluoroquinolones, and rifampin for biofilm infections / Steven L. Barriere -- [beta][beta]-lactams for the treatment of biofilm-associated infections / Ingrid L. Dodge, Karen Joy Shaw, and Karen Bush -- Glycopeptide antibacterials and the treatment of biofilm-related infections / John L. Pace, Roasaire Verna, and Jan Verhoef -- Antibiotic resistance in biofilms / Nafsika H. Georgopapadakou -- Treatment protocols for infections of vascular catheters / Russell E. Lewis and Issam I Raad -- Treatment protocols for bacterial endocarditis and infection of electrophysiologic cardiac devices / Martin E. Stryjewski and G. Ralph Corey -- Treatment protocol of infections of orthopedic devices / Vera Antonios, Elie Berbari, and Douglas Osmon.
- 2010 SpringerHéctor M. Alvarez, editor.Systematics of Members of the Genus Rhodococcus (Zopf 1891) Emend Goodfellow et al. 1998: The Past, Present and Future / Volker Gűrtler and Robert J. Seviour -- The Rhodococcal Cell Envelope: Composition, Organisation and Biosynthesis / Iain C. Sutcliffe, Alistair K. Brown and Lynn G. Dover -- Genomes and Plasmids in Rhodococcus / Michael J. Larkin, Leonid A. Kulakov and Christopher C. R. Allen -- Central Metabolism of Species of the Genus Rhodococcus / Héctor M. Alvarez -- Adaptation of Rhodococcus to Organic Solvents / Carla C. C. R. de Carvalho -- Catabolism of Aromatic Compounds and Steroids by Rhodococcus / Katherine C. Yam, Robert van der Geize and Lindsay D. Eltis -- Catabolism of Nitriles in Rhodococcus / Ludmila Martínková, Miroslav Pátek, Alicja Barbara Veselá, Ondřej Kaplan and Bronislava Uhnáková, et al. -- The Desulfurization Pathway in Rhodococcus / Ting Ma -- Application of Rhodococcus in Bioremediation of Contaminated Environments / Maria S. Kuyukina and Irena B. Ivshina -- Physiology, Biochemistry, and Molecular Biology of Triacylglycerol Accumulation by Rhodococcus / Héctor M. Alvarez and Alexander Steinbüchel -- Rhodococcus Biosurfactants: Biosynthesis, Properties, and Potential Applications / Maria S. Kuyukina and Irena B. Ivshina -- Phytopathogenic Strategies of Rhodococcus fascians / Elisabeth Stes, Marcelle Holsters and Danny Vereecke -- Rhodococcus equi and Its Pathogenic Mechanisms / José A. Vázquez-Boland, Michal Letek, Ana Valero-Rello, Patricia González and Mariela Scortti, et al.
- 2007 Springervolume editors, R.J. Howard, N.A.R. Gow
- 2008 SpringerDaryl S. Paulson.
- 2010 Springeredited by Ramkrishna Sen.Also available: Print – 2010
- 2011 SpringerGloria Soberón-Chávez, editor.Biosurfactants: A General Overview / Gloria Soberón-Chávez and Raina M. Maier -- Rhamnolipids: Detection, Analysis, Biosynthesis, Genetic Regulation, and Bioengineering of Production / Ahmad Mohammad Abdel-Mawgoud, Rudolf Hausmann, Francois Lépine, Markus M. Müller and Eric Déziel -- Surfactin and Other Lipopeptides from Bacillus spp. / Philippe Jacques -- Serrawettins and Other Surfactants Produced by Serratia / Tohey Matsuyama, Taichiro Tanikawa and Yoji Nakagawa -- Trehalolipids / Zongze Shao -- Mannosylerythritol Lipids: Microbial Production and Their Applications / J. Arutchelvi and M. Doble -- Sophorolipids / Inge N. A. Van Bogaert and Wim Soetaert.
- 2013 SpringerAndreas Rummel, Thomas Binz, editors.The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion.Also available: Print – 2013
- 2006Michael T. Madigan, John M. Martinko.Microorganisms and microbiology -- An overview of microbial life -- Macromolecules -- Cell structure/function -- Nutrition, laboratory culture, and metabolism of microorganisms -- Microbial growth -- Essentials of molecular biology -- Metabolic regulation -- Essentials of virology -- Bacterial genetics -- Microbial evolution and systematics -- Prokaryotic diversity : the bacteria -- Prokaryotic diversity : the archaea -- Eukaryotic cell biology and eukaryotic microorganisms -- Microbial genomics -- Viral diversity -- Metabolic diversity -- Methods in microbial ecology -- Microbial ecology -- Microbial growth control -- Microbial interactions with humans -- Essentials of immunology -- Molecular immunology -- Diagnostic microbiology and immunology -- Epidemiology -- Person-to-person microbial diseases -- Animal-transmitted, arthropod-transmitted, and soilborne microbial diseases -- Wastewater treatment, water purification, and waterborne microbial diseases -- Food preservation and foodborne microbial diseases -- Industrial microbiology -- Genetic engineering and biotechnology.
- 2009Michael T. Madigan, John M. Martinko, Paul V. Dunlap, David P. Clark.
- v. 1-4, 1999-2002. Springer
- v. 5-, 2002- Springer
- Characterization of an RNaseIII protein and its potential roles in the RNA interference pathway of the protozoan parasite, Entamoeba histolytica2012Justine Michelle Pompey.Entamoeba histolytica, a human intestinal parasite and a leading cause of death worldwide, contains a complex repertoire of endogenous small RNAs. Core elements of the RNAi machinery have been identified in the E. histolytica genome including three Argonaute proteins (EhAgo2-1, EhAgo2-2, and EhAgo2-3) and two genes with RNA-directed RNA polymerase (RdRP) domains. However, to date no canonical Dicer enzyme, an RNaseIII endonuclease responsible for cleaving double-stranded RNA (dsRNA) to 20-30nt small RNAs and a critical player in the RNAi pathway, has been identified in the E. histolytica genome. We conducted bioinformatics searches of the genome which revealed only one gene with an RNaseIII domain, EhRNaseIII. Interestingly, this candidate lacks the canonical Dicer structure - it is substantially smaller than other Dicers, contains only a single RNaseIII domain, and lacks PAZ or double-stranded RNA binding domain (dsRBD). Most eukaryotic Dicer proteins identified to date contain two RNaseIII domains, which form a heterodimer required for cleavage of the dsRNA, and contain PAZ or dsRBDs. We determined that EhRNaseIII exists as a homodimer in E. histolytica trophozoites. We sought to probe the contributions of EhRNaseIII, EhAgo2-2, and EhRdRP1 to the RNAi pathway in E. histolytica. Attempts to downregulate these genes using RNA-based methods including antisense mediated silencing and the production of gene-specific secondary small RNAs were unsuccessful. Expression of EhRNaseIII dominant-negative mutants also failed to impair production of small RNAs. In order to determine if EhRNaseIII was capable of generating small RNAs of the size observed in E. histolytica trophozoites, we conducted in vitro cleavage assays of dsRNA. Despite using multiple protein sources (E. histolytica whole cell lysate, immunoprecipitated EhRNaseIII, and recombinant EhRNaseIII protein) and two structurally distinct dsRNA substrates, we were unable to detect small RNA cleavage products. We further investigated whether EhRNaseIII was sufficient to act as a Dicer enzyme by co-expressing it with a dsRNA substrate in Saccharomyces cerevisiae, which lacks an RNAi pathway. However, no small RNAs were detected. We also assessed whether EhAgo2-2, which associates with 5'-polyphosphate small RNAs in E. histolytica, could mediate silencing using 5'-monophosphated small RNAs in S. cerevisiae. No downregulation in reporter transcript or protein was observed. These data indicate that EhRNaseIII is not a minimal Dicer enzyme and suggest that small RNA biogenesis may occur solely through a Dicer-independent small pathway in E. histolytica. These data also suggest that EhAgo2-2 may be specific for 5'-polyphosphate small RNAs. Future studies will continue to investigate the mechanism of small RNA-induced silencing in E. histolytica.
- 2010Patrick Ryan Eimerman.Listeria monocytogenes is a facultative intracellular pathogen that causes severe invasive disease in susceptible populations. Using in vivo bioluminescent imaging, it was recently discovered that this bacterium can colonize the murine gallbladder of otherwise asymptomatic mice. This finding was surprising as L. monocytogenes, after invasion of the intestines, was thought to survive only intracellularly in an infected host and in the gallbladder the bacteria lived extracellularly. It was also surprising that a bacterium could grow and replicate in the pure bile environment of the gallbladder lumen as bile is a potent antimicrobial compound. In this study, we characterized how Listeria monocytogenes is able to reach the gallbladder during infection and examined how this pathogen is able to survive in this environment. Using a mouse adapted L. monocytogenes which expresses a modified InlA capable of binding murine E-cadherin we were able to follow the kinetics of gallbladder colonization after oral infection using in vivo bioluminescent imaging. We then utilized surgical manipulation of the mouse host and repeated the oral infection to determine how L. monocytogenes reaches the gallbladder. Once we had determined the mechanism of gallbladder entry, we then utilized whole genome microarrays to characterize the transcriptome of L. monocytogenes during in vivo growth in the gallbladder and in freshly isolated murine bile. Finally, we attempted to determine what nutrients are utilized by L. monocytogenes during growth in bile and looked at the ability of other bacterial species to grow in this environment. Through these experiments we demonstrated regular asymptomatic gallbladder colonization by L. monocytogenes after oral infection and that L. monocytogenes reaches the gallbladder via the hepatic duct only after first causing systemic infection and escaping the liver. We also demonstrated that the lifestyle in the gallbladder is similar to that in the intestine with the exception of the need for bile resistance genes, and finally that it appears as though simple carbon sources may be utilized during bile growth and that bile may not be as toxic to bacteria as has been thought. Our work suggests that gallbladder colonization may not be exclusive to only L. monocyctogenes and Salmonella Typhi since other bacteria can grow, and in some cases better than L. monocyctogenes, in pure bile.
- v. 1-2, 2004. ScienceDirectv. 2 (2004) ScienceDirectedited by Patrick F. Fox ... [et al.].v. 1. General aspects -- v. 2. Major cheese groups.
- v. 1-2, 2006-07. Springerv. 2, 2007 SpringerLetts, L. Gordon; Moser, Bernhard; Neote, Kuldeep.v. 1. Immunology of chemokines / Bernhard Moser, Gordon L. Letts [sic], Kuldeep Neote (editors) -- v. 2. Pathophysiology of chemokines / Kuldeep Neote, Gordon L. Letts [sic], Bernard Moser (editors).Also available: Print – v. 1-2, 2006-07.
- pt. A-B, 2009. ScienceDirectpt. B ScienceDirectedited by Tracy M. Handel and Damon J. Hamel.Chemokines and receptors in disease -- Chemokine related proteins from pathogens -- Atypical and novel chemoattractants and receptors -- Chemokine signaling.Also available: Print – pt. A-B, 2009.
- 2009 SpringerKeya Chaudhuri, S.N. Chatterjee.
- 2008 SpringerDenis H. Lynn.
- 2008 ClinicalKeyW. John Spicer ; illustrated by Peter Lamb and Robert Britton.Microbes -- Microbial attack and control by intrinsic defences -- Specific pathogens. Bacteria ; Fungi ; Arthropods ; Parasites ; Viruses -- Microbial attack succeeds : clinical infection -- Microbe control by extrinsic defences.
- 2007Mark Gladwin, Bill Trattler.
- 2010 Springeredited by Iqbal Ahmad, Mohammad Owais, Mohammed Shahid, Farrukh Aqil"Presents recent research developments to aid fighting fungal infections The currently available means of combating fungal infections are still weak and clumsy. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. Interestingly, several novel antifungal drug targets have already been identified and validated. However, it is too early to expect any novel antifungal drug as drug discovery programs are still in their infancy. In addition to classical and genomic approaches to drug discovery, traditional knowledge derived from natural products and phytomedicine can provide a multitude of alternative modes of combating fungal infection. This book comprises 20 chapters on various aspects pertaining to fungal diseases in human and animals, their reservoir, fungal pathogenesis, their management and recent advances in their treatment. Issues of antifungal drug toxicity, especially nephrotoxicity, are also discussed. The development of resistance in fungal pathogens, including multidrug resistance and its mechanism, is dealt with in two chapters. Diverse diagnostic approaches to fungal infections are also reviewed. The combinational drug strategies used in combating invasive fungal infections are addressed in detail. The management of pulmonary mycoses in stem cell transplantation is also given special focus. Novel antifungal drugs (synthetic and herbal), fungal vaccines, and metabolic pathways as drug targets are discussed in detail in three different chapters. Subsequently the roles of innate immunity, cytokine therapy and immunomodulators in the treatment of fungal infections are elaborated upon. As novel drug delivery systems have a great potential for modifying the pharmacokinetics of medications, the last chapter takes this fact into consideration in its examination of state-of-the-art delivery systems in controlling fungal infections."--Publisher's website.
- 2011Yana Emmy Evangeline Hoy.The importance of the intestinal microbiota to the health of an organism is well recognized. Alterations in the composition of the microbiota are associated with a number of diseases. However, the extent to which the microbiota varies across healthy individuals and time and the causes of this variation are still not fully understood. In order to distinguish between microbial community states of health and disease, the range of healthy microbial communities must be determined. In addition, the effect of perturbations on the microbiota is an area of active research. Recent studies indicate that intestinal infections can have a significant impact on the composition of intestinal microbiota. However, the extent and duration of these changes during different infections have not been fully characterized. My aims were to characterize the range of healthy microbiota in an inbred mouse population over time and to determine the dynamics of alterations in the microbiota during disease. I also wanted to determine if certain characteristics of the microbiota make animals more or less susceptible to infection. In this work, 46 individual healthy mice were sampled over time to assess the range of microbial communities in health. A mouse model of Salmonella enterica serovar Typhimurium infection was used to assess the impact of infection on the microbiota. Mice were sampled prior to infection and over the course of infection. This work finds that the microbiota of healthy mice varies significantly over time and among individuals. However, there are stable differences among individual mice, which may be established at the point of weaning when adult microbial communities develop. In addition, this work finds significant changes in the microbiota during infection that differ with the level of infection. This data also shows that there are some taxa whose abundance prior to infection correlates with outcome of infection. This work provides insights into the dynamics of the microbiota in health and disease and its impact on the health of the host.
- 2006 Springervolume editor, Jessup M. Shively.
- 2013 WileySaroj K. Mishra, Dipti Agrawal.Introduction -- Host-microbe interactions -- Antibiotics and other chemotherapeutic agents -- Antiseptics and disinfectants -- Gram-positive cocci -- Gram-positive bacilli -- Gram-positive bacteria with rudimentary filaments -- Gram-negative cocci -- Gram-negative bacilli -- Miscellaneous gram-negative bacteria -- Spirochetes and bacteria without a cell wall -- Actinomycetes -- Introduction to pathogenic fungi and superficial mycoses -- Subcutaneous and systemic mycoses -- Unicellular parasites -- Multicellular parasites -- Viruses and prions.
- 2011 SpringerGabriele Halwachs-Baumann, editor.Congenital cytomegalovirus (CMV) infection is the most common intrauterine transmitted viral infection, with a tremendous impact on fetuses and newborns. In this book the history of this disease, its pathophysiological background, epidemiology and symptoms, as well as diagnostic and therapeutic strategies, will be discussed. Since economic aspects are gaining more and more importance in health politics, one chapter is dedicated to this issue in the context of congenital CMV infection. The content is based on the latest scientific findings and written in an understandable manner, allowing persons not working in the field of congenital CMV to also profit from it. Thus, this book is of interest for medical doctors, nurses, midwives, economists, but also for men and women who want to inform themselves about this topic.
- 2008 SpringerNaomi Balaban, editor ; foreword by J. William Costerton.
- 2015 Springer Protocolsedited by Helena Jane Maier, Erica Bickerton, Paul Britton.Coronaviruses : an overview of their replication and pathogenesis / Anthony R. Fehr and Stanley Perlman -- Identification of a novel coronavirus from Guinea Fowl using metagenomics / Mariette F. Ducatez and Jean-Luc Guérin -- Serological diagnosis of feline coronavirus infection by immunochromatographic test / Tomomi Takano and Tsutomu Hohdatsu -- Estimation of evolutionary dynamics and selection pressure in coronaviruses / Muhammad Munir and Martí Cortey -- Preparation of chicken tracheal organ cultures for virus isolation, propagation, and titration / Ruth M. Hennion -- Preparation of chicken kidney cell cultures for virus propagation / Ruth M. Hennion and Gillian Hill -- Isolation and propagation of coronaviruses in embryonated eggs / James S. Guy -- Characterization of human coronaviruses on well- differentiated human airway epithelial cell cultures / Hulda R. Jonsdottir and Ronald Dijkman -- Quantification of infectious bronchitis coronavirus by titration in vitro and in ovo / Joeri Kint, Helena Jane Maier, and Erik Jagt -- Purification of coronavirus virions for Cryo-EM and proteomic analysis / Stuart Dent and Benjamin W. Neuman -- Partial purification of IBV and subsequent isolation of viral RNA for next-generation sequencing / Sarah M. Keep, Erica Bickerton, and Paul Britton -- Transient dominant selection for the modification and generation of recombinant infectious bronchitis coronaviruses / Sarah M. Keep, Erica Bickerton, and Paul Britton -- Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes / Fernando Almazán ... [et al.] -- Protein histochemistry using coronaviral spike proteins : studying binding profiles and sialic acid requirements for attachment to tissues / Iresha N. Ambepitiya Wickramasinghe and M. Hélène Verheije -- Identification of protein receptors for coronaviruses by mass spectrometry / V. Stalin Raj ... [et al.] -- Single particle tracking assay to study coronavirus membrane fusion / Deirdre A. Costello and Susan Daniel -- Studying coronavirus-host protein interactions / Chee-Hing Yang ... [et al.] -- Field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions / Pierre- Olivier Vidalain ... [et al.] -- Investigation of the functional roles of host cell proteins involved in coronavirus infection using highly specific and scalable RNA interference (RNAi) approach / Jean Kaoru Millet and Béatrice Nal -- Transcriptome analysis of feline infectious peritonitis virus infection / Parvaneh Mehrbod ... [et al.] -- Quantification of interferon signaling in avian cells / Joeri Kint and Maria Forlenza -- Studying the dynamics of coronavirus replicative structures / Marne C. Hagemeijer and Cornelis A. M. de Haan -- Preparation of cultured cells using high-pressure freezing and freeze substitution for subsequent 2D or 3D visualization in the transmission electron microscope / Philippa C. Hawes.
- 2013 SpringerHideaki Yukawa, Masayuki Inui, editors.Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its "microbial factory" qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
- v. 1-<9>, 1977-<1988>editors, Allen I. Laskin, Hubert A. Lechevalier.v. 1. Bacteria.--v. 2. Fungi, algae, protozoa, and viruses.--v. 3. Microbial composition : amino acids, proteins, and nucleic acids.--v. 4. Microbial composition : carbohydrates, lipids, and minerals.--v. 5. Microbial products.--v. 6. Growth and metabolism.--v. 7. Microbial transformation.--v. 8. Toxins and enzymes.--v. 9, pt. A. Antibiotics.
- 2013 SpringerRodolphe Barrangou, John van der Oost, editors.CRISPR-Cas is a recently discovered defense system which protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR-Cas immune systems has been identified in at least half of the available prokaryotic genomes. On-going biochemical and functional analyses have resulted in substantial insight into the functions and possible applications of these fascinating systems, although many secrets remain to be uncovered. In this book, experts summarize the state of the art of this exciting field.
- 2015 ScienceDirectedited by Andew Sails and Yi-Wei Tang.Chapter 1. Total laboratory automation in clinical bacteriology -- Chapter 2. MALDI-TOF mass spectrometry for microorganism identification -- Chapter 3. POC tests in microbial diagnostics: current status -- Chapter 4. Molecular diagnostics in the diagnosis of parasitic infection -- Chapter 5. Clinical applications of quantitative real-time PCR in virology -- Chapter 6. Low-density TaqMan® array cards for the detection of pathogens -- Chapter 7. Invasive fungal infections and approaches to their diagnosis -- Chapter 8. Technical and software advances in bacterial pathogen typing -- Chapter 9. Molecular strain typing and characterisation of toxigenic Clostridium difficile -- Chapter 10. Accurate whole-genome sequencing-based epidemiological surveillance of Mycobacterium Tuberculosis -- Chapter 11. Solid and suspension microarrays for microbial diagnostics -- Chapter 12. Gene amplification and sequencing for bacterial identification -- Chapter 13. Host-based diagnostics for detection and prognosis of infectious diseases -- Chapter 14. MALDI-TOF mass spectrometry in the clinical microbiology laboratory: beyond identification -- Chapter 15. Next-generation sequencing for pathogen detection and identification -- Chapter 16. Virology: the next generation from digital PCR to single virion genomics -- Chapter 17. Artificial nucleic acid probes and their applications in clinical microbiology -- Index.
- 2006- Wileyeditorial board, Richard Coico ... [et al.].Emerging technologies -- Microscopy -- Alpha proteobacteria -- Beta proteobacteria -- Enteric gamma proteobacteria -- Nonenteric gamma proteobacteria -- Delta proteobacteria -- Epsilon proteobacteria -- Firmicutes (low G+C gram positive) -- Actinobacteria (high G+C gram positive) -- Chlamydiae -- Spirochetes -- Other eubacteria -- Animal DNA viruses -- Animal RNA viruses -- Plant RNA viruses.
- v. 285-, 2005- SpringerAlso available: Print – v. 40-241, 243-, 1967-99, , 2001-
- 2011 Springeredited by Mark W. Robinson, John P. Dalton."Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research"--Provided by publisher.Also available: Print – 2011
- 2006Paul Singleton, Diana Sainsbury.
- 2013 Springer Protocolsedited by Ludwig Eichinger, Francisco Rivero.Amoebozoa / Christina Schilde and Pauline Schaap -- Model organism Dictyostelium discoideum / Salvatore Bozzaro -- Comparative genomics of the dictyostelids / William F. Loomis -- One stop shop for everything Dictyostelium : dictyBase and the dicty stock center in 2012 / Petra Fey [and others] -- Fluorescent reporters and methods to analyze fluorescent signals / Annette Müller-Taubenberger and Hellen C. Ishikawa-Ankerhold -- Collection and cultivation of dictyostelids from the wild / Tracy E. Douglas [and others] -- Identification and verification of microRNAs by high-throughput sequencing / Jimmie Hällman [and others] -- Transcriptional profiling of Dictyostelium with RNA sequencing / Edward Roshan Miranda [and others] -- Analysis of chromatin organization by deep sequencing technologies / James L. Platt [and others] -- Pharmacogenetics of resistance to cisplatin and other anticancer drugs and the role of sphingolipid metabolism / Stephen Alexander, William S. Swatson, and Hannah Alexander -- N-glycomic and n-glycoproteomic studies in the social amoebae / Christa L. Feasley -- Measuring cheating, fitness, and segregation in Dictyostelium discoideum / Neil J. Buttery [and others] -- Application of the Cre-loxP system for generating multiple knock-out and knock-in targeted loci / Jan Faix [and others] -- Extrachromosomal inducible expression / Douwe M. Veltman and Peter J.M. Van Haastert -- Isolation of Dictyostelium nuclei for light and electron microscopy / Petros Batsios [and others] -- Investigation of DNA repair pathway activity / Anne-Marie C. Couto, Nicholas D. Lakin, and Catherine J. Pears -- Transcript localization in Dictyostelium discoideum cells by RNA FISH / Patrick Hofmann, Janis Kruse, and Christian Hammann -- Analysis of mitochondrial gene expression / Jessica E. Accari [and others] -- Mitochondrial respiratory complex function and the phenotypic consequences of dysfunction / Sarah J. Annesley [and others] -- Micropipette aspiration for studying cellular mechanosensory responses and mechanics / Yee-Seir Kee and Douglas N. Robinson -- Quantitative analysis of phagocytosis and phagosome maturation / Natascha Sattler, Roger Monroy, and Thierry Soldati -- Setting up and monitoring an infection of Dictyostelium discoideum with mycobacteria / Sonia Arafah [and others] -- Isolation of pathogen-containing vacuoles / Olga Shevchuk and Michael Steinert -- Immunomagnetic purification of fluorescent legionella-containing vacuoles / Ivo Finsel, Christine Hoffmann, and Hubert Hilbi -- Secretory lysosomes in Dictyostelium : visualization, characterization, and dynamics / Wanessa C. Lima and Pierre Cosson -- Monitoring autophagy in Dictyostelium / Ana Mesquita [and others].
- 2011Kaitian Peng.Francisella is a gram-negative bacterium that causes tularemia. It is capable of infecting a remarkably broad host range including humans, mammals, birds and fish via multiple different routes of infection, establishing a successful colonization event within the various organs. This facultative, intracellular pathogen is also capable of invading a broad range of host cell types ranging from macrophages to fibroblasts. This is an extremely fascinating facet of the bacterium. The ability of Francisella to infect such a wide range of hosts and cell types suggests that the bacterium either co-opts cellular mechanisms common to all hosts and cell types or has the requisite bacterial genes to adapt to many different intraorganismal environments, or both. We were interested in studying the diverse repertoire of interactions that may occur between the bacterium and its murine host. In this thesis, the transposon site hybridization (TraSH) negative selection strategy was applied in a range of in vivo and in vitro systems to identify novel host-pathogen interactions in Francisella. We subsequently demonstrated that Francisella require tryptophan for virulence specifically in the lungs due to lung-specific induction of a host innate immune molecule indoleamine 2,3-dioxygenase 1. Alveolar macrophages may also deplete intracellular trytophan via a novel mechanism and microbial lung-specific requirement of tryptophan for virulence may be widely applicable to all bacterial species. We also demonstrate that Francisella hypercytotoxic mutants, unlike previously suggested, induce macrophage hypercytotoxicity due to increased bacteriolysis in the intracellular milieu. Identification and characterization of bacterial mutants that are attenuated under different in vitro and in vivo conditions have led to further insights into the interactions that occur between Francisella and its murine host.
- 2009 SpringerVadrevu Sree Hari Rao, Ponnada Raja Sekhara Rao.Basic models -- Chemostat versus the lake -- Instability tendencies -- Self-regulation -- Wall growth -- Zones of no activation -- Influence of the control mechanisms -- Parameter estimation using dynamic optimization.
- 2012 CRCnetBASEAbdelhamid Ajbar, Khalid Alhumaizi.1. Introduction to stability of bioreactors -- 2. Introduction to bioreactors models -- 3. Introduction to stability and bifurcation theory -- 4. The basic model of ideal chemostat -- 5. The chemostat with wall attachment -- 6. Pure and simple microbial competition -- 7. Stability of continuous recombinant DNA cultures -- 8. Biodegradation of mixed substrates -- 9. Predator-prey interactions -- 10. Ratio-dependent models -- 11. Models with product formation -- 12. Models with product formation : type II models -- 13. Models with product formation : type III models -- 14. Operability of nonideal bioreactors -- 15. Operability of prefermentation of cheese culture -- 16. Biodegradation of wastewater -- 17. Dynamics of activated sludge reactors -- 18. Complex dynamics in forced bioreactors.
- 2012 ScienceDirectStephen M. King.Research on dyneins has a direct impact on human diseases, such as viruses and cancer. With an accompanying website showing over one hundred streaming videos of cell dynamic behavior for best comprehension of material, Dynein: Structure, Biology and Disease is the only reference covering the structure, biology and application of dynein research to human disease. From bench to bedside, Dynein: Structure, Biology and Disease offers research on fundamental cellular processes to researchers and clinicians across developmental biology, cell biology, molecular biology, biophysics, biomedicine, genetics and medicine. . Broad-based up-to-date resource for the dynein class of molecular motors . Chapters written by world experts in their topics . Numerous well-illustrated figures and tables included to complement the text, imparting comprehensive information on dynein composition, interactions, and other fundamental features.
- 2013 SpringerLori Frappier.Introduction -- Roles of EBNA1 at EBV Episomes -- EBNA1-DNA Interactions -- EBNA1 Contributions to EBV-Associated Tumours -- Cellular Effects of EBNA1 -- Conclusion.
- Ecology in the dentist's chair : patterns of biogeography and stability in human subgingival microbial communities2013Katie Marie Shelef.Recent work on the human microbiome represents the essence of community ecology: "What makes assemblages of species more or less similar to each other at different places and times?" (Vellend 2010; Anderson et al. 2011). The complex microbial communities of the human subgingival crevice are particularly relevant since multiple, spatially distinct but ecologically similar sites are found in a single subject. Healthy sites and sites affected by periodontitis (gum disease) can coexist in the same mouth simultaneously; periodontal disease may reflect community processes since it is thought to have a polymicrobial etiology rather than a single species etiology in the tradition of Koch's postulates. Subgingival communities therefore provide a unique, clinically relevant context to apply ecological concepts. The goal of this work was to advance our ecological understanding of the human subgingival microbiota, drawing on two fields of ecological research: biogeography and the stability of complex communities. The first half of this work explored oral biogeography and treating subgingival sites as isolated, island-like patches of similar habitat distributed within a mouth. A survey of twenty-three to thirty subgingival sites per mouth within five periodontally healthy subjects uncovered non-random, spatially relevant patterns of community distributions. Specifically, a left-right symmetric pattern of community similarity and a positive correlation between physical distance between sites and the dissimilarity of their respective communities were observed. However, these patterns were only discernable among deeply sequenced communities. Additional applications of co-occurrence analysis and neutral theory models to the data indicated that both competitive interactions and stochastic, demographic processes influence distributions of subgingival taxa. The second half of this work assessed the temporal stability of health and periodontitis-associated subgingival and salivary microbial communities before and after a single disturbance event of professional teeth cleaning. Communities were surveyed in 8 subjects (4 healthy, 4 with moderate chronic periodontitis), at 4 sites per subject, and at four sampling times ranging from 2 weeks to 1 day before the cleaning to assess baseline spatial and temporal variation. Samples collected at seven time points ranging from 1 hour to 3 months after the cleaning were also examined in order to monitor the compositional response to the perturbation. The results of this work demonstrated that healthy and periodontitis-associated subgingival communities are resilient to a teeth-cleaning perturbation, but the displacement of community composition immediately after cleaning was greater in periodontitis than in health. Periodontitis-associated subgingival communities more closely resembled a health-like composition as they recovered from the cleaning, although this change was transient. Salivary communities were also shown to be resilient to a teeth cleaning perturbation, but the impact of the cleaning on community composition is less pronounced in saliva. The results further suggest that post-cleaning residual subgingival communities contribute more to subgingival recolonization than salivary communities. The results of this work generated testable hypotheses about the ecological mechanisms governing observed spatial and temporal patterns. I hope these findings will contribute to the development of novel, ecologically informed approaches to the clinical treatment of the subgingival environment.
- 2009 Springer Protocolsby John R. Crowther.
- 2012 ClinicalKeyJeffrey K. Actor.This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in immunology and microbiology while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material.
- Elucidating Toxoplasma gondii's engagement with the host : identification of dense granule protein 25 (GRA25), a novel member of the parasite's arsenal and characterization of strain-specific differences in the modulation of host immune responses2013Anjali Joshi Shastri.The ubiquitous parasite Toxoplasma gondii has developed an exquisite arsenal of effectors to support its intracellular lifestyle and its persistence within its diverse hosts. In order to survive and resist clearance, this obligate intracellular parasite must contend with the host immune response. Different strains of the parasite vary dramatically in their interaction with the immune system, and studying these strain differences has furthered our understanding of the spectrum of host-pathogen interactions and led to the identification of parasite effectors. The work described here dissects the interactions between different strains of the parasite and host macrophages: innate immune cells that paradoxically both serve as a niche for parasite replication and defend the host against parasite infection. Chapter 1 introduces Toxoplasma, the immune response to infection, and discusses the role of known parasite effectors. Experiments described in Chapter 2 identify a novel secreted parasite factor, GRA25, which modulates cytokine secretion in macrophages and controls parasite virulence in mice. In Chapter 3, high throughput methods are used to characterize the transcriptional and phosphorylation landscape of macrophages infected with different Toxoplasma strains. These analyses demonstrate that a secreted polymorphic tyrosine kinase, ROP16, directs murine macrophage polarization towards an alternatively activated phenotype. They also reveal that Toxoplasma parasites activate the Type I interferon response, a response classically associated with cytosolic pathogens. Chapter 4 describes work demonstrating that Toxoplasma strain-specifically modulates the innate immune response via secretion of a parasite factor, MAF1, which recruits host mitochondria to the parasitophorous vacuole. Finally, Chapter 5 discusses the future directions and implications of this work in the broader context of host-pathogen interactions.
- A fully searchable, working editorial site of articles by scientists and scientific historians in the fields of biochemistry and physiology, cell biology, developmental biology, ecology, evolution, genetics, immunology, molecular biology, neuroscience, microbiology and virology, plant science, structural biology, and science and society.
- 2009 ScienceDirecteditor-in-chief, Moselio Schaechter.Subject Classification: -- Applied Microbiology: Agro/Food -- Applied Microbiology: Industrial -- Archaea -- Bacteria -- Cell Structure Chemical Composition -- Environmental Microbiology and Ecology -- Evolution and Systematics -- Fungi -- Genetics, Genomics -- History and Culture, (and Biographies) -- Mutualism and Commensalism -- Pathogenesis -- Physiology -- Protists -- Public Issues -- Techniques -- Viruses.
- 2015 SpringerFriedrich Koch-Nolte, editor.Part I. Evolution and detection of endogenous ADP-ribosylation. The natural history of ADP-ribosyltransferases and the ADP-ribosylation system / L. Aravind, Dapeng Zhang, Robson F. de Souza, Swadha Anand and Lakshminarayan M. Iyer -- Identification and analysis of ADP-ribosylated proteins / Friedrich Haag and Friedrich Buck -- Part II. ADP-ribosylation by ARTCs (R-S-E ARTs). Photorhabdus luminescens Toxins TccC3 and TccC5: insecticidal ADP-ribosyltransferases that modify threonine and glutamine / Klaus Aktories, Gudula Schmidt and Alexander E. Lang -- Reaction mechanism of mno-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein / Hideaki Tsuge and Toshiharu Tsurumura -- Regulation of nitrogenase by reversible mono-ADP-ribosylation / Vivian R. Moure, Flavia F. Costa, Leonardo M. Cruz, Fabio O. Pedrosa, Emanuel M. Souza, Xiao-Dan Li, Fritz Winkler and Luciano F. Huergo -- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells / Björn Rissiek, Friedrich Haag, Olivier Boyer, Friedrich Koch-Nolte and Sahil Adriouch -- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish / Tsuyoshi Nakano, Azusa Takahashi-Nakaguchi, Masafumi Yamamoto and Masahiko Watanabe -- Part III. ADP-ribosylation by ARTDs (H-Y-E ARTs). Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family / Ana Filipa Pinto and Herwig Schüler -- Function and regulation of the mono-ADP-ribosyltransferase ARTD10 / Max Kaufmann, Karla L.H. Feijs and Bernhard Lüscher -- Regulation of nucleocytoplasmic transport by ADP-tibosylation: the emerging role of Karyopherin-[Beta]1 mono-ADP-ribosylation by ARTD15 / Maria Di Girolamo -- Index.
- 2010 SpringerJohannes H.P. Hackstein, editor.Free-Living Protozoa with Endosymbiotic Methanogens / Tom Fenchel and Bland J. Finlay -- Anaerobic Ciliates and Their Methanogenic Endosymbionts / Johannes H. P. Hackstein -- Symbiotic Methanogens and Rumen Ciliates / Kazunari Ushida -- The Methanogenic and Eubacterial Endosymbionts of Trimyema / Naoya Shinzato and Yoichi Kamagata -- Termite Gut Flagellates and Their Methanogenic and Eubacterial Symbionts / Yuichi Hongoh and Moriya Ohkuma -- Methanogens in the Digestive Tract of Termites / Andreas Brune -- Methanogenic Archaea in Humans and Other Vertebrates / Everly Conway de Macario and Alberto J. L. Macario -- Methanogens in the Gastro-Intestinal Tract of Animals / Johannes H. P. Hackstein and Theo A. van Alen -- Syntrophy in Methanogenic Degradation / Petra Worm, Nicolai Müller, Caroline M. Plugge, Alfons J. M. Stams and Bernhard Schink -- Hydrogenosomes / Johannes H. P. Hackstein and Aloysius G. M. Tielens -- Evolution of Prokaryote-Animal Symbiosis from a Genomics Perspective / Rosario Gil, Amparo Latorre and Andrés Moya.
- 2013David Halladin.This thesis examines three topics that are related to the Gram-positive bacterial cell envelope. First, I examine how transmembrane proteins navigate through the thick, heavily cross-linked Gram-positive cell wall while remaining anchored to the bacterial membrane. I develop a theoretical model that predicts that entropic confinement of a disordered protein can drive translocation through the cell wall. I experimentally test important predictions of the model to demonstrate that translocation depends on the length of the translocating protein and the geometry of the bacterial surface, while demonstrating that entropy-driven translocation occurs in a variety of Gram-positive species. Second, I study how the antimicrobial peptide nisin causes cell death in Gram-positive bacteria. I demonstrate that nisin treatment triggers membrane collapse in multiple Gram-positive species, and provide evidence that collapse is initiated by an increase in compressive stress in the membrane. Finally, I examine the process of cell division in the Gram-positive coccus Staphylococcus aureus. Contrary to the current view of S. aureus division, cell volume increases monotonically during the cell cycle, as opposed to occurring entirely during cell separation. I observed a dramatic millisecond hemisphere-to-sphere transition during cell separation that was accompanied by a decrease in surface area, suggesting that separation is associated with a redistribution of cell wall stress.
- 2007 Springervolume editors, C.P. Kubicek, I.S. Druzhinina.
- 2005 ScienceDirectedited by Jared R. Leadbetter.Cultivation -- Physiological ecology -- Nucleic acid techniques.Also available: Print – 2005
- 2014 Springer Protocolsedited by Ian T. Paulsen, Andrew J. Holmes.Methods for isolation and cultivation of filamentous fungi / Helena Nevalainen, Liisa Kautto, and Junior Te'o -- Rapid extraction of PCR-competent DNA from recalcitrant environmental samples / Michael R. Gillings -- Quantitative PCR for detection of mRNA and gDNA in environmental isolates / Anthony J. Brzoska and Karl A. Hassan -- Analysis of community dynamics in environmental samples using denaturing gradient gel electrophoresis / Claire L. Thompson -- Terminal restriction fragment length polymorphism (T-RFLP) profiling of bacterial 16S rRNA genes / Catherine A. Osborne -- Profiling the diversity of microbial communities with single-strand conformation polymorphism (SSCP) / Achim Schmalenberger and Christoph C. Tebbe -- Human fecal source identification with real-time quantitative PCR / Orin C. Shanks ... [and 4 others] -- Next generation barcode tagged sequencing for monitoring microbial community dynamics / Katy Breakwell, Sasha G. Tetu, and Liam D.H. Elbourne -- Analysis of methanotroph community structure using a pmoA-based microarray / Guy C.J. Abell ... [and 3 others] -- Biolog Phenotype MicroArrays for phenotypic characterization of microbial cells / Amanda M. Mackie ... [and 3 others] -- Visualization of metabolic properties of bacterial cells using nanoscale secondary ion mass spectrometry (NanoSIMS) / Yi Vee Chew, Andrew J. Holmes, and John B. Cliff -- Single-cell Raman sorting / Mengqiu Li ... [and 3 others] -- Bacterial whole-cell biosensors for the detection of contaminants in water and soils / Yun Wang ... [and 3 others] -- Stable isotope probing to study functional components of complex microbial ecosystems / Sophie Mazard and Hendrik Schäfer -- Metagenomics using next-generation sequencing / Lauren Bragg and Gene W. Tyson -- Targeted genomics of flow cytometrically sorted cultured and uncultured microbial groups / Sophie Mazard ... [and 4 others] -- Quantitative microbial metatranscriptomics / Scott Gifford, Brandon Satinsky, and Mary Ann Moran -- Quantitative metaproteomics : functional insights into microbial communities / Chongle Pan and Jillian F. Banfield.
- 2011 SpringerCarol A. Kauffman, Peter G. Pappas, Jack D. Sobel, William E. Dismukes, editors."Clinical Mycology" offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.
- World Health Organization, Food and Agriculture Organization of the United Nations.Exposure assessment is one of the four steps of microbiological risk assessment. This volume provides guidelines for the exposure assessment of microbiological hazards in food. It outlines the principles of exposure assessment as well as the data needed and approaches available for carrying out exposure assessment.--Publisher's description.Also available: Print – 2008
- 2007 ScienceDirectedited by Fred A. Rainey and Aharon Oren.
- 2015 SpringerSikha Mandal, Jnanendra Rath.This volume presents recent developments in the novel drug development and potential of extremophilic cyanobacteria. It discusses how these tiny organism originated, produce oxygen that leads to evolution of life on the earth, how their survival strategies in extreme climatic conditions lead to diverse metabolic pathways, and the opportunity to use them to develop novel drugs. The book is comprised of five chapters, starting with the origin of cyanobacteria, their survival strategies under extreme conditions, and their capabilities to change metabolic activities.The second chapter explores the different metabolic pathways found in cyanobacteria and examines advances in this field and recent techniques like MALDI-TOF imaging and metagenomics tools as well as in silico techniques for rapid screening of secondary metabolites. Further chapters cover the glycomics of cyanobacteria, anticancer drug development, and some issues and challenges of using cyanobacteria to develop drugs. Extremophilic Cyanobacteria For Novel Drug Development provides insight into future perspectives in drug development and is a key resource for students, researchers and professionals in pharmacy, medicinal chemistry, pharmacognosy biotechnology, biology, and academics.
- 2006 Springer[edited by] Harald Wajant.FasL and Fas: typical members of the TNF ligand and receptor family / Anja Krippner-Heidenreich and Peter Scheurich -- FasL-independent activation of Fas / Faustino Mollinedo and Consuelo Gajate -- Role of ceramide in CD95 signaling / Volker Teichgräber, Gabriele Hessler and Erich Gulbins -- Regulation of Fas signaling by FLIP proteins / Margot Thome -- Fas-induced necrosis / Tom Vanden Berghe ... [et al.] -- Fas - more than an apoptosis inducer / Harald Wajant -- Retrograde Fas ligand signaling -- FasL and Fas in liver homeostasis and hepatic injuries -- Fas-activation, development and homeostasis of T cells / Georg Häcker -- The FasL-Fas system in disease and therapy -- Tools for activation and neutralization of Fas signaling.
- 2014 SpringerMarc Daëron, Falk Nimmerjahn, editors.This volume provides a state-of-the-art update on Fc Receptors (FcRs). It is divided into five parts. Part I, Old and New FcRs, deals with the long-sought-after Fc[micro]R and the recently discovered FCRL family and TRIM21. Part II, FcR Signaling, presents a computational model of Fc[epsilon]RI signaling, novel calcium channels, and the lipid phosphatase SHIP1. Part III, FcR Biology, addresses major physiological functions of FcRs, their glycosylation, how they induce and regulate both adaptive immune responses and inflammation, especially in vivo, FcR humanized mice, and the multifaceted properties of FcRn. Part IV, FcRs and Disease, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection. In Part V, FcRs and Therapeutic Antibodies, the roles of various FcRs, including FcgRIIB and FcbRI, in the immunotherapy of cancer and autoimmune diseases using monoclonal antibodies and IVIg are highlighted. All 18 chapters were written by respected experts in their fields, offering an invaluable reference source for scientists and clinicians interested in FcRs and how to better master antibodies for therapeutic purposes.
- 2012 SpringerEssam Kotb.
- 2007 Springeredited by E. Velázquez and C. Rodriguez-Barrueco.
- 2006 CRCnetBASEedited by Morris Potter.pt. 1. Factors that influence interactions between foodborne pathogenic agents and consumers -- pt. 2. Human host factors that influence foodborne disease -- pt. 3. Agent factors of pathogenicity and virulence that influence foodborne disease.
- 2013 Am Soc Microbioledited by Michael P. Doyle, Robert L. Buchanan.Factors of special significance to food microbiology -- Microbial spoilage and public health concerns -- Foodborne pathogenic bacteria -- Nonbacterial pathogens -- Preservatives and preservation methods -- Fermentations and beneficial microorganisms -- Advanced techniques in food microbiology.
- 2007 CRCnetBASEedited by Jan Dijksterhuis, Robert A. Samson.
- 2006 CRCnetBASEedited by Clive de W. Blackburn.pt. 1. Detection and analysis of food spoilage -- pt. 2. Managing food spoilage -- pt. 3. Spoilage yeasts -- pt. 4. Spoilage moulds -- pt. 5. Spoilage bacteria.
- 2007 Springeredited by Shabbir Simjee ; foreword by Toni L. Poole.Escherichia coli / Jianghong Meng and Carl M. Schroeder -- Listeria / Franz Allerberger -- Clostridium botulinum and Clostridium perfringens / Jim McLauchlin and Kathie A. Grant -- Yersinia enterocolitica and Yersinia pseudotuberculosis / Maria Fredriksson-Ahomaa -- Foodborne pathogenic vibrios / T. Ramamurthy and G. Balakrish Nair -- Enterococcus and its association with foodborne illness / Simona F. Oprea and Marcus J. Zervos -- Foodborne viral hepatitis / Hazel Appleton ... [et al.] -- Gastroenteric virus / Miren Iturriza-Gómara, Chris I. Gallimore, and Jim Gray -- Cryptosporidium / Huw V. Smith -- Toxoplasma gondii / Dolores E. Hill ... [et al.] -- Aflatoxins : background, toxicology, and molecular biology / Joan W. Bennett, S. Kale, and Jiujiang Yu -- Scombroid fish poisoning / Elijah W. Stommel -- Pathogen control in meat and poultry production: implementing the USDA food safety and inspection service's hazard analysis and critical control point system / Moshe S. Dreyfuss ... [et al.] -- Use of antimicrobials in food animal production / Frank M. Aaestrup and Lars B. Jensen -- Alternatives to antimicrobials* / Toni L. Poole, Todd R. Callaway, and David J. Nisbet -- Microbial risk assessment / Carl M. Schroeder -- Food irradiation and other sanitation procedures / Donald W. Thayer -- Molecular techniques of detection and discrimination of foodborne pathogens and their toxins / Steven L. Foley and Kathie A. Grant -- Future directions in food safety* / Ross C. Beier and Suresh D. Pillai.
- 2008 SpringerArun K. Bhunia.
- AccessMedicine Lange Case files — Foodborne microbial pathogens : mechanisms and pathogenesis (100)
- Food-borne pathogens : methods and protocols — Microbiology of waterborne diseases : microbiological aspects and risks. Second edition. [2nd ed.] (100)
- Microbiology of wounds — Systems biology in biotech & pharma : a changing paradigm (100)
- Systems biology of bacteria — Yeast systems biology : methods and protocols (30)
- Harrison's Principles of Internal Medicine
- AAP Red Book Online
- Robbins & Cotran Pathologic Basis of Disease
- Sabiston Textbook of Surgery
- Nelson's Textbook of Pediatrics
- Surgical Exposures in Orthopaedics
- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
- Red Book Online
- ICU Book
- Primary Care Medicine
- Campbell-Walsh Urology
Access restricted to Stanford community
Shortcut to Licensed Content
TO INSTALL, DRAG THIS BUTTON to your browser Bookmarks or Tools Bar.
Bookmark on Other Websites
- TO INSTALL, RIGHT CLICK this button.
- Select "Add to Favorites" (click “Continue” if you see a security alert)
- From the "Create in" menu, select “Favorites Bar” (IE8, IE9) to install
- Once installed it will look like this
- Click "Bookmark on Lane" to bookmark any webpage
- Your saved bookmark will appear on this page
Can't find it?
Look if we have it in print
- Springer Protocols
- Lange Series
- National Academy Press
- NCBI Bookshelf
- Thieme Atlases
A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.
Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed Plus is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available.Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.
Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences.
Includes cited reference searching, citation maps, and an analyze tool.
Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not.
Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.The National Guideline Clearinghouse (NGC): A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.
Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities.
In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.
A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.
Over 10,000 notes outline the status of specific infections within each country.
Provides online, full-text access to Springer's journal titles as well as journals from other publishers.
Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.