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Laboratory Animal Science

  • Patent and licensing issues in transgenic technology /Karen S. Canady --Global resources : including gene trapped ES cell clones -- is your gene already knocked out /Lluis Montoliu --Designing transgenes for optimal expression /Eduardo Molto, Cristina Vicente-Garcıa, and Lluis Montoliu --Gene targeting vector design for embryonic stem cell modifications /Thomas L. Saunders --Transgenic production benchmarks /Thomas J. Fielder and Lluis Montoliu --Generation of transgenic mice by pronuclear microinjection /Katja Becker and Boris Jerchow --Generation of transgenic rats using microinjection of plasmid DNA or lentiviral vectors /Severine Menoret ... [et al.] --Generation of transgenic animals by use of YACs /Almudena Fernandez, Diego Munoz, and Lluis Montoliu --BAC transgenes, DNA purification, and transgenic mouse production /Michael G. Zeidler, Margaret L. Van Keuren, and Thomas L. Saunders --Generation of transgenic animals with lentiviral vectors /Carlos Lois --Vertebrate transgenesis by transposition /Aron Geurts, Darius Balciunas, and Lajos Mates --Rat spermatogonial stem cell-mediated gene transfer /Karen M. Chapman ... [et al.] --Mouse cloning by nuclear transfer /Sayaka Wakayama, Nguyen Van Thuan, and Teruhiko Wakayama --Gene targeting in embryonic stem cells /Elizabeth D. Hughes and Thomas L. Saunders --Importance of mouse ES cell line selection /Wojtek Auerbach and Anna B. Auerbach --Tetraploid complementation assay /Marina Gertsenstein --Combining ES cells with embryos /Elizabeth Williams ... [et al.] --Derivation of murine ES cell lines /Kristina Nagy and Jennifer Nichols --Rat embryonic stem cell derivation and propagation /Ping Li ... [et al.] --Induced pluripotency : generation of iPS cells from mouse embryonic fibroblasts /Han Li ... [et al.] --Preparation and analysis of DNA for use in transgenic technology /Anna B. Auerbach, Peter J. Romanienko, and Willie H. Mark --Colony management /Karen Brennan --Cryopreservation /B. Pintado and J. Hourcade --Shipment of mice and embryos /Shirley Pease --Pathogen-free mouse rederivation by IVF, natural mating and hysterectomy /J.M. Sztein, R.J. Kastenmayer, and K.A. Perdue --Refinement, reduction, and replacement /Jan Parker-Thornburg.
  • Animal hematotoxicology 2008, CRCnetBASE
    Hemopoiesis, blood cell types, and bone marrow examination -- Erythrocytes, anemias, and polycythemia -- Additional erythrocytic measurements -- Iron, associated proteins, and vitamins -- Leukocytes -- Immunotoxicology -- Hemostasis -- Pre-analytical variables -- Analytical variables and biosafety -- Data processing and interpretation.
  • Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, canc
  • General principles of animal selection and normal physiological values -- Preanesthesia, anesthesia, chemical restraint, and the recognition and treatment of pain and distress -- Normal cardiac function parameters -- Measuring cardiac function -- Measuring vascular function and ventricular/arterial coupling dynamics -- Isolated heart preparations, problems, and pitfalls -- Cardiovascular effects of anesthetics, sedatives, postoperative analgesic agents, and other pharmaceuticals -- Naturally occurring and iatrogenic animal models of valvular, infectious, and arrhythmic cardiovascular disease -- Iatrogenic models of ischemic heart disease -- Iatrogenic, transgenic, and naturally occurring models of cardiomyopathy and heart failure -- Iatrogenic, congenic, and transgenic models of hypertension -- Naturally occurring, iatrogenic and transgenic models of atherosclerotic disease -- Animal models for the study of neurohumeral and central neural control of the cardiovascular system -- Other transgenic animal models used in cardiovascular studies
  • The mouse -- The rat -- The hamster -- The guinea pig -- The rabbit -- The ferret -- The dog -- Primates -- The minipig -- Alternative species / Shayne C. Gad -- Clinical pathology of laboratory animals / Robert L. Hall -- Model selection and scaling / Shayne C. Gad -- Susceptibility factors / Shayne C. Gad -- Laws and regulations governing animal care and use in research / Shayne C. Gad.
  • Animal welfare 2008, Springer
  • 1. Introduction / Piper M. Treuting, Suzanne M. Dintzis, Kathleen S. Montine -- 2. Phenotyping / Cory Brayton, Piper M. Treuting -- 3. Necropsy and Histology / Sue Knoblaugh, Julie Randolph-Habecker, Steve Rath -- 4. Mammary Gland / Robert D. Cardiff, Kimberly H. Allison -- 5. Skeletal System / Christopher Jerome, Benjamin Hoch -- 6. Nose, Sinus, Pharynx, and Larynx / Jack R. Harkema, Stephan A. Carey, James G. Wagner, Suzanne M. Dintzis, Denny Liggitt -- 7. Oral Cavity and Teeth / Piper M. Treuting, Thomas H. Morton Jr. -- 8. Salivary Glands / Piper M. Treuting, Suzanne M. Dintzis -- 9. Respiratory / Carlos Jose Suarez, Suzanne M. Dintzis, Charles W. Frevert -- 10. Cardiovascular / Michael A. Laflamme, Manu M. Sebastian, Bernard S. Buetow -- 11. Upper Gastrointestinal Tract / Piper M. Treuting, Mark A. Valasek, Suzanne M. Dintzis -- 12. Lower Gastrointestinal Tract / Piper M. Treuting, Suzanne M. Dintzis -- 13. Liver and Gallbladder / Arlin B. Rogers, Renee Z. Dintzis -- 14. Pancreas / Suzanne M. Dintzis, Denny Liggitt -- 15. Endocrine System / Krista Marie DuBray La Perle, C. Diana Jordan -- 16. Urinary System / Piper M. Treuting, Jolanta Kowalewska -- 17. Female Reproductive System / Mara H. Rendi, Atis Muehlenbachs, Rochelle L. Garcia, Kelli L. Boyd -- 18. Male Reproductive System / Sue Knoblaugh, Lawrence True -- 19. Hematopoietic and Lymphoid Tissues / Michael Linden, Jerrold M. Ward, Sindhu Cherian -- 20. Nervous System / Catherine E. Hagan, Brad Bolon, C. Dirk Keene -- 21. Special Senses: Eye / Piper M. Treuting, Rachel Wong, Daniel C. Tu, Isabella Phan -- 22. Special Senses: Ear / Piper M. Treuting, Suzanne M. Dintzis -- 23. Skin and Adnexa / John P. Sundberg, Lillian B. Nanney, Philip Fleckman, Lloyd E. King.
  • Diplomatic theory and practice -- International funding for animal protection -- International conferences and delegation management -- The media as a tool for diplomacy -- Important associations and international organizations -- Epilogue
  • Bioethics and animal care -- Control of stress and distress -- Management of pain in laboratory animals -- Anesthesia and analgesia -- Euthanasia -- Antibiotics -- Operating theatre -- Rat identification -- Antisepsis, sterilization, and asepsis -- Suture -- Substances administration -- Samples -- Catheterization of the femoral artery and vein -- Cardiac catheterization -- Cannulation of the thoracic duct -- Tracheostomy -- In situ isolation of the stomach -- In situ isolation of the intestinal loop -- Intestinal everted sacs -- In situ perfusion of the small intestine -- Experimental models for the study of diabetes -- Islets of langerhans isolation -- Incubation of pancreatic tissue slices -- In situ perfusion of the pancreas -- Experimental pancreatitis -- Hepatic circulation impairment -- Extrahepatic cholestasis model -- Adrenalectomy -- Ovariectomy -- Thyroparathyroidectomy -- Parathyroid glands -- Measurement techniques of renal parameters -- Kidney isolation and perfusion -- Acute renal failure models -- Renal blood flow measurement -- Transport studies in plasma membrane vesicles isolated from renal cortex -- Remnant kidney model -- Experimental myocardial infarction -- Experimental arteriosclerosis -- Isolated heart: langendorff technique -- Polyclonal antibodies preparation -- Histological procedures -- Bones and bone tissue -- Equipment -- Solution preparation -- Normal values in IIm/Fm rat subline "M".
  • "Incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. Provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates."--Publisher's description (excerpt).
  • v. 2, 2003 CRCnetBASE
    v. 3, 2005 CRCnetBASE
    v. 1. Essential principles and practices -- v. 2-3. Animal models.
  • Handbook of laboratory animal science. 3rd ed. v. 1, 3, 20011, 2014., CRCnetBASE
    v. 3, 2014 CRCnetBASE
    v. 1. Essential principles and practices. -- v. 2. Animal models.
  • Humanized mice 2008, Springer
    Basic Concept of Development and Practical Application of Animal Models for Human Diseases / Tatsuji Nomura, N. Tamaoki, A. Takakura and H. Suemizu, p. 25-51-- Humanized SCID Mouse Models for Biomedical Research / T. Pearson, D. L. Greiner and L. D. Shultz, p. 53-76 -- NOD/Shi-scid IL2rγnull (NOG) Mice More Appropriate for Humanized Mouse Models / M. Ito, K. Kobayashi and T. Nakahata, p. 77-86 -- Humanizing Bone Marrow in Immune-Deficient Mice / K. Ando, Y. Muguruma and T. Yahata, p. 87-94 -- The Differentiative and Regenerative Properties of Human Hematopoietic Stem/Progenitor cells in NOD-SCID/IL2rγnull Mice / F. Ishikawa, Y. Saito, S. Yoshida, M. Harada and L. D. Shultz, p. 95-107 -- Antigen-Specific Antibody Production of Human B Cells in NOG Mice Reconstituted with the Human Immune System / M. Ito, M. Shiina, Y. Saito, Y. Tokuda and Y. Kametani, et al., p. 109-124 -- Humanized Immune System (HIS) Mice as a Tool to Study Human NK Cell Development / N. D. Huntington and J. P. Di Santo, p. 125-131 -- Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice / S. Baenziger, P. Ziegler, L. Mazzucchelli, L. Bronz and R. F. Speck, et al., p. 133-148 -- Humanized Mice for Human Retrovirus Infection / Y. Koyanagi, Y. Tanaka, M. Ito and N. Yamamoto, p. 149-165 -- Functional and Phenotypic Characterization of the Humanized BLT Mouse Model / A. K. Wege, M. W. Melkus, P. W. Denton, J. D. Estes and J. V. Garcia, p. 167-177 -- Novel Metastasis Models of Human Cancer in NOG Mice / M. Nakamura and H. Suemizu, p. 179-196 -- In Vivo Imaging in Humanized Mice / H. Masuda, H. J. Okano, T. Maruyama, Y. Yoshimura and H. Okano, et al.
  • Preparing for anaesthesia -- Anaesthesia -- Anaesthetic management -- Special techniques -- Analgesia and post-operative care -- Anaesthesia of common laboratory species : special considerations.
  • Laboratory ferret 2012, CRCnetBASE
    "This book deals with the care and humane treatment of the laboratory ferret. Renowned for its inquisitive nature, the ferret is helping advance the current state of medical knowledge because its biological characteristics have allowed it to emerge as an important laboratory animal model for the study of human viral respiratory diseases such as influenza"--Provided by publisher.
  • Laboratory fish 2000, ScienceDirect
  • Laboratory mouse 2001, CRCnetBASE
  • Laboratory mouse. 2nd ed. 2012, ScienceDirect
  • Laboratory nonhuman primate 2002, CRCnetBASE
  • Laboratory primate 2005, ScienceDirect
  • The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well illustrated reference includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. With many expert contributors, this will be an extremely valuable publication for biomedical researchers, laboratory animal veternarians and other professionals engaged in laboratory animal science. A new gold standard publication from the American College of Laboratory Animal Medicine series One stop resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu Includes up-to-date, common experimental methods Organized by species for easy access during bench research.
  • Laboratory rat. 2nd ed. 2013, CRCnetBASE
    Important biological features -- Husbandry -- Management -- Veterinary care -- Experimental methodology.
  • Laboratory rat. 2nd ed. 2006, ScienceDirect
    Historical foundations / J. Russell Lindsey and Henry J. Baker -- Ethical and legal perspectives / Beverly J. Gnadt -- Taxonomy and stocks and strains / Hans J. Hedrich -- Morphophysiology / John Hofstetter, Mark A. Suckow, and Debra L. Hickman -- Clinical pathology of the rat / Bruce D. Car ... [et al.] -- Reproduction and breeding / Jeffrey J. Lohmiller and Sonya P. Swing -- Assisted reproductive technologies and genetic modifications in rats / Yuksel Agca and John K. Critser -- Analysis of behavior in laboratory rats / Ian Q. Whishaw ... [et al.] -- Nutrition / Sherry M. Lewis ... [et al.] -- Housing and environment / Robert E. Faith and Jack R. Hessler -- Bacterial, mycoplasmal and mycotic infections / Steven H. Weisbroth, Dannis F. Kohn, and Ron Boot -- Viral disease / Robert O. Jacoby and Diane J. Gaertner -- Parasitic diseases / David G. Baker -- Neoplastic disease / Gary A. Boorman and Jeffrey I. Everitt -- Metabolic, traumatic, and miscellaneous diseases / William W. King and Steven P. Russell --Medical management and diagnostic approaches / Glen Otto and Craig L. Franklin -- Occupational health and safety / Sanford H. Feldman and David N. Easton -- Experimental modeling and research methodology / Michael A. Koch -- Anesthesia and analgesia / George A. Vogler -- Euthanasia and necropsy / Jeffrey I. Everitt and Elizabeth A. Gross -- Integrating biology with rat genomic tools / Carol Moreno-Quinn and Howard J. Jacob -- Gnotobiotics / Philip b. Carter and Henry L. Foster -- Spontaneous, surgically and chemically induced models of disease / Dwight R. Owens -- The nude rat / Martha A. Hanes -- Gerontology and age-associated lesions / Nancy L. Nadon -- Cardiovascular research / Peter G. Anderson, Sanford P. Bishop, and J. Thomas Peterson -- Toxicology / Thomas E. Hamm, Mary Ann Vasbinder, and Angela King-Herbert -- Embryology and teratology / Carol Erb -- Immunology / Veronica Jennings and Dirck Dillehay -- Wild and black rats / Marc Hulin and Robert Quinn.
  • The basics of managing a laboratory animal facility -- The organizational environment -- The management of human resources -- Managing financial resources -- Management of information resources -- Time management -- Leadership.
  • Chapter 1. Introduction to the Research Process -- Chapter 2. Mice -- Chapter 3. Tests of Mouse Behavior -- Chapter 4. Designs -- Chapter 5. Sample Size -- Chapter 6. Ethics Approval -- Chapter 7. Logistics -- Chapter 8. Getting Ready for Testing -- Chapter 9. Prelude to Data Analysis -- Chapter 10. Domains and Test Batteries -- Chapter 11. Motivating Mice -- Chapter 12. Qualities of Behavioral Tests -- Chapter 13. Task Refinement and Standardization -- Chapter 14. Video Tracking -- Chapter 15. The Laboratory Environment.
  • Post-transcriptional Control of Gene Expression During Mouse Oogenesis /Hugh J. Clarke --Polarity and Asymmetry During Mouse Oogenesis and Oocyte Maturation /Malgorzata Kloc, Rafik M. Ghobrial, Ewa Borsuk and Jacek Z. Kubiak --Chromatin Structure and ATRX Function in Mouse Oocytes /Rabindranath De La Fuente, Claudia Baumann and Maria M. Viveiros --Cyclin B in Mouse Oocytes and Embryos: Importance for Human Reproduction and Aneuploidy /Zbigniew Polański, Hayden Homer and Jacek Z. Kubiak --Src Protein Kinases in Mouse and Rat Oocytes and Embryos /Mattan Levi, Lihi Ninio-Mani and Ruth Shalgi --Gradual Meiosis-To-Mitosis Transition in the Early Mouse Embryo /Aurélien Courtois and Takashi Hiiragi --Maternal Control of Mouse Preimplantation Development /Wenjing Zheng and Kui Liu --Preimplantation Mouse Embryo: Developmental Fate and Potency of Blastomeres /Aneta Suwińska --Creation of Trophectoderm, the First Epithelium, in Mouse Preimplantation Development /Yusuke Marikawa and Vernadeth B. Alarcon --Cell Lineage Allocation Within the Inner Cell Mass of the Mouse Blastocyst /Panagiotis Xenopoulos, Minjung Kang and Anna-Katerina Hadjantonakis --Formation of Distinct Cell Types in the Mouse Blastocyst /Samantha A. Morris and Magdalena Zernicka-Goetz --Cell Movements in the Egg Cylinder Stage Mouse Embryo /Bradley Joyce and Shankar Srinivas --Balancing the Dose in the Mouse /Mary E. Donohoe --Mouse Oviduct Development /C. Allison Stewart and Richard R. Behringer --Cell Lineages, Growth and Repair of the Mouse Heart /Fabienne Lescroart and Sigolène M. Meilhac --Cellular Reprogramming During Mouse Development /Zoë D. Burke, Gabriela Miron-Buchacra and David Tosh --Differentiation of Definitive Endoderm from Mouse Embryonic Stem Cells /Peter T. W. Kim and Christopher J. Ong --Mouse and Human Pluripotent Stem Cells and the Means of Their Myogenic Differentiation /I. Grabowska, K. Archacka, A. M. Czerwinska, M. Krupa and M. A. Ciemerych --Stem Cells and Corneal Epithelial Maintenance: Insights from the Mouse and Other Animal Models /Richard L. Mort, Panagiotis Douvaras, Steven D. Morley, Natalie Dorà and Robert E. Hill, et al. --Mouse-Induced Pluripotent Stem Cells /Hui Zhang and Ying Jin --Aging in the Mouse and Perspectives of Rejuvenation Through Induced Pluripotent Stem Cells (iPSCs) /Ken-ichi Isobe, Zhao Cheng, Sachiko Ito and Naomi Nishio.
  • Fulltext v. 2 ScienceDirect
    V. 1. Biology and management -- v. 2. Diseases.
  • Small animal imaging 2011, Springer
  • Biology, handling, husbandry, and anatomy -- Anesthesia, analgesia, and perioperative care -- Wound closure and integument -- Gastrointestinal procedures --Liver and biliary system -- Pancreas and spleen -- Urinary system and adrenal glands -- The reproductive system -- Cardiothoracic and vascular surgery/chronic intravascular catheterization -- Head and neck surgery/central nervous system -- Musculoskeletal system and orthopedic procedures -- Cardiovascular catheterization, electrophysiology, and imaging laboratory procedures -- Endoscopic, laparoscopic, and minimally invasive surgery -- Xenotransplantation and transgenic technologies --Toxicology -- Radiobiology -- Imaging techniques: CT, MRI, and PET scanning -- Ossabaw Island miniature swine: cardiometabolic syndrome assessment.
  • Introduction: strategies for developing genetically modified mice / Marten H. Hofker -- Genetic modification of the mouse: general technology - pronuclear and blastocyst injection / Jan Willem Voncken -- Generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos / Jérôme Artus and Anna-Katerina Hadjantonakis -- Cryopreservation of mouse spermatozoa and in vitro fertilization / Naomi Nakagata -- Autopsy and histological analysis of the transgenic mouse / Marion J.J. Gijbels and Menno P.J. de Winther -- Transgene design / Bart van de Sluis and Jan Willem Voncken -- Inducible transgenic mouse models / Thomas L. Saunders -- Lentiviral transgenesis / Terunaga Nakagawa and Casper C. Hoogenraad -- Transgenesis in mouse embryonic stem cells / Janine van Ree, Wei Zhou, Ming Li, and Jan M. van Deursen -- Engineering BAC reporter gene constructs for mouse transgenesis / Yu Fu and Peter Maye -- Targeting vector construction through recombineering / Liviu A. Malureanu -- Generating conditional knockout mice / Roland H. Friedel, Wolfgang Wurst, Benedikt Wefers, and Ralf Kühm -- Hypomorphic mice / Darren J. Baker -- MICER targeting vectors for manipulating the mouse genome / Chunbong Liu, Paul F. Szurek, and Y. Eugene Yu -- Knock-in approaches / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans -- Generation of a series of knock-in alleles using RMCE in ES cells / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans -- Selection of targeting mutants from a library of randomly mutagenized ES cells / Kyoji Horie, George Gaitanaris, and Alexander Gragerov -- Generation of genetically modified rodents using random ENU mutagenesis / Ruben van Boxtel and Edwin Cuppen -- Bone marrow transplantations of study gene function in hematopoietic cells / Menno P.J. de Winther and Peter Heeringa -- Adenovirus-mediated gene transfer / Ko Willems van Dijk, Kyriakos E. Kyreos, Frits J. Fallaux, and Jurre Hageman.

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