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Evidence-Based MedicineAccess restricted to Stanford unless otherwise noted

  • "The Consummate Clinician offers hospital-based physicians an organizing framework for coping with daily challenges both in patient care and in teaching. The book describes in a highly formatted, easily accessible way exactly how physicians and physicians-in-training can think critically and act decisively in this age of medical information overload. Special emphasis is on (1) error avoidance and reduction - a topic that has long been championed by hospitalists, (2) efficient practice management for best patient outcomes and improved cost control, (3) the use of evidence-based medicine, and (4) improving communication among and between physicians and other staff in the hospital setting. Using real-world clinical examples and scenarios, the book focuses on essential topics, many of which tend to fall between the cracks of print and electronic resources. Pearls and pitfalls of gathering, processing, and communicating medical information are presented, but more than these, this book is meant as a kind of clinical GPS--a way of helping hospital-based physicians find their clinical coordinates and keep their bearings in the face of new challenges and uncertainties. In addition to the clinical scenarios featured throughout, additional mini-cases are collected at the end of the book. The over-arching goal of this new resource is to enrich the way hospital-based physicians think about diagnosis, therapy, and prognosis, especially at the warp-speed of "ward world," which increasingly lurches between the frazzled and the frantic"--Provided by publisher.
  • Fulltext ClinicalKey
    Cervical disk herniation : anterior cervical diskectomy and fusion versus arthroplasty / Mir H. Ali, Frank M. Phillips -- Multilevel anterior cervical diskectomy and fusion : bone-grafting options / Sheeraz A. Qureshi, Andrew C. Hecht, Scott D. Boden -- Ossification of the posterior longitudinal ligament : anterior versus posterior approach / Garrick W. Cason, Edward R. Anderson III, Harry N. Herkowitz -- Minimally invasive approaches to thoracic disk herniations / Alfred T. Ogden, Michael G. Kaiser, Richard G. Fessler -- Lumbar disk herniation with mild neurological deficit : microdiskectomy versus conservative treatment / Kelli L. Crabtree, Paul M. Arnold -- Cervical spondylosis-spinal stenosis : laminoplasty versus laminectomy and fusion / Yu-Po Lee, Niraj Patel, Steven R. Garfin -- Lumbar degenerative disk disease : fusion versus artificial disk / Michael F. Duffy, Jack E. Zigler -- Degenerative spondylolisthesis with radicular pain : decompression only versus decompression and fusion / Tuan V. Nguyen, Robert A. McGuire Jr. -- Asymptomatic intradural Schwannoma : surgery versus radiosurgery versus observation / Christopher E. Mandigo, Paul C. McCormick -- Pseudotumor : transoral versus posterior fusion / Daniel M. Sciubba ... [et al.] -- Odontoid fracture in the elderly : odontoid screws versus posterior fusion / Harvey E. Smith, Scott D. Daffner, Alexander R. Vaccaro -- C1-C2 fusion : transarticular screws versus Harms procedure / Thomas J. Kesman, Bradford L. Currier -- Multilevel cervical corpectomy : anterior-only versus circumferential instrumentation / Andrew J. Schoenfeld, Christopher M. Bono -- Cervical jumped facets and incomplete neurological deficit : closed reduction versus urgent surgery / Michael A. Finn, Paul A. Anderson -- Laminectomy across cervico thoracic junction : fusion versus non fusion / Timothy E. Link, Rahul Jandial, Volker K.H. Sonntag -- Vertebral metastases : ventral and dorsal approach versus lateral -- Extracavitary transpedicular approach / John H. Shin, Edward C. Benzel -- Degenerative scoliosis: anterior and posterior fusion versus posterior fusion / Krishna Gumidyala, Sigurd Berven -- Sagittal imbalance: multiple Smith-Petersen osteotomies versus pedicle substraction osteotomies / Jamal McClendon ... [et al.] -- -- L1-S1 fusion: extending to T12 and pelvis and when to include L5-S1 anterior grafting / Steven Mardjetko -- High-grade spondylolisthesis : reduction and fusion versus in situ fusion / Matthew B. Maserati, Christopher I. Shaffrey, Adam S. Kanter.
  • The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.
  • "This book presents the first evidence-based casebook for hospitalists and other hospital-based physicians, associated staff, and trainees. Each clinical chapter concludes with practical "pearls" for application to the user's own practice, while a free CD contains all images and case summaries in PowerPoint files. Based on and expanded from the wildly popular Clinical Care Conundrum (CCC) series in the Journal of Hospital Medicine, this attractive new volume combines high-quality images and text to form an indispensable reference and study text for the wards or the classroom"--Provided by publisher.
  • "The Cochrane Handbook for Systematic Reviews of Interventions (the Handbook) provides guidance to authors for the preparation of Cochrane Intervention reviews (including Cochrane Overviews of reviews)." "The Handbook is updated regularly to reflect advances in systematic review methodology and in response to feedback from users. Please refer to the web site for the most recent version, for interim updates to the guidance and for details of previous versions of the Handbook."
  • Recent trends in health care across the United States and internationally have emphasized a novel approach that consists in comparing the effectiveness and efficacy of treatment interventions with a patient-centered emphasis (i.e., evidence-based health care), while ensuring cost constraints, maximizing benefits, and minimizing risks. In this book, experts in comparative effectiveness and efficacy research and analysis for practice (CEERAP) in health care in general address a range of topical issues. The emphasis is on implications for endodontics and nursing, both of which are considered in a series of detailed chapters. Commonalities and differences among CEERAP, utility-based and logic-based analysis and decision-making, and evidence-based and patient-centered practice are defined and discussed. The book concludes by examining applications for CEERAP in developing patient-centered optimal treatment interventions for the next decade.
  • Nationally recognized experts equip the reader with practical, actionable guidance on all of the challenges faced every day in hospital medicine, making it easier to provide optimal care for every patient in an efficiently managed unit.
  • Metabolic alterations of cancer cells / Marco Sciacovelli, Edoardo Gaude, Mika Hilvo, and Christian Frezza -- Autophagy and cancer metabolism / Juliet Goldsmith, Beth Levine, and Jayanta Debnath -- Regulation of cancer metabolism by oncogenes and tumor suppressors / Raffaella Iurlaro, Clara Lucía León-Annicchiarico, and Cristina Muñoz-Pinedo -- Cross talk between cell death regulation and metabolism / Simone Fulda -- Techniques to monitor glycolysis / Tara TeSlaa and Michael A. Teitell -- Measurement of enolase activity in cell lysates / Keigo Fukano and Kazuhiro Kimura / Extracellular flux analysis to monitor glycolytic rates and mitochondrial oxygen consumption / Martin Pelletier, Leah K. Billingham, Madhu Ramaswamy, and Richard M. Siegel -- Conventional techniques to monitor mitochondrial oxygen consumption / Hélène Simonnet, Arnaud Vigneron, and Jacques Pouysségur -- Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry / Gerhard Krumschnabel, Andrea Eigentler, Mario Fasching, and Erich Gnaiger -- Kinetic analysis of local oxygenation and respiratory responses of mammalian cells using intracellular oxygen-sensitive probes and time-resolved fluorometry / Alexander V. Zhdanov, Ruslan I. Dmietriev, James Hynes, and Dmitri B. Papkovsky -- Cell-based measurements of mitochondrial function in human subjects / Ju-Gyeong Kang, Ping-yuan Wang, and Paul M. Hwang -- Use of chemical probes to detect mitochondrial ROS by flow cytometry and spectrofluorometry / Jing Chen and Clayton E. Mathews -- Methods to monitor ROS production by fluorescence microscopy and fluorometry / Aleksandra Wojtala, Massimo Bonora, Dominika Malinska, Paolo Pinton, Jerzy Duszynski, and Mariusz R. Wieckowski -- Genetically encoded redox sensor / Wai Kan Chiu, Atif Towheed, and Michael J. Palladino -- Use of genetically encoded sensors to monitor cytosolic ATP/ADP ratio in living cells / Andrei I. Tarasov and Guy A. Rutter -- Methods to monitor and compare mitochondrial and glycolytic ATP production / Simone Patergnani, Federica Baldassari, Elena De Marchi, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski, and Paolo Pinton -- Measurement of ADP-ATP exchange in relation to mitochondrial transmembrane potential and oxygen consumption / Christos Chinopoulos, Gergely Kiss, Hibiki Kawamata, and Anatoly A. Starkov -- Real-time assessment of the metabolic profile of living cells with genetically encoded NADH sensors / Yuzheng Zhao, Yi Yang, and Joseph Loscalzo -- 13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells / Jie Zhang, Woo Suk Ahn, Paulo A. Gameiro, Mark A. Keibler, Zhe Zhang, and Gregory Stephanopoulos -- Measurement of fatty acid oxidation rates in animal tissues and cell lines / Frank K. Huynh, Michelle F. Green, Timothy R. Koves, and Matthew D. Hirschey -- Methods to assess lipid accumulation in cancer cells / Jørgen Sikkeland, Yang Jin, and Fahri Saatcioglu -- Analysis of hypoxia-induced metabolic preprogramming / Chendong Yang, Lei Jiang, Huafeng Zhang, Larissa A. Shimoda, Ralph J. Bernardinis, and Gregg L. Semenza.
  • Diabetes from growth hormone excess / Neggers, S.J., van der Lely, A.J. -- Diabetes in growth hormone deficiency / Prodam, F., Zavattaro, M., Caputo, M., Marzullo, P., Aimaretti, G. -- Diabetes associated with glucocorticoid excess / Janssen, J.A.M.J.L., Lamberts, S.W. -- Diabetes in hyperaldosteronism / Crudo, V., Mulatero, P., Monticone, S., Veglio, F. -- Diabetes from catecholamine excess / Mannelli, M., Parenti, G., Zampetti, B., Canu, L., Mannucci, E. -- Diabetes and hyperthyroidism / Mitrou, P., Dimitriadis, G., Raptis, S.A. -- Diabetes secondary to neuroendocrine gastroenteropancreatic tumors / Minuto, F., Ferone, D., Boschetti, M., Albertelli, M., Gatto, F. -- Type 2 diabetes in polycystic ovary syndrome / Pasquali, R., Gambineri, A. -- Diabetes in hyperparathyroidism / Thomas, A., Kautzky-Willer, A. -- Posttransplant diabetes / Secchi, A., Scavini, M. -- Diabetes in pancreatitis, pancreatectomy, and other pancreatic diseases / Tiengo, A., Vigili de Kreutzenberg, S., Del Prato, S. -- Fibrocalculous pancreatic diabetes / Unnikrishnan, R., Mohan, V. -- Diabetes and hemochromatosis / Wood, M.J., Gonsalkorala, E.S., Powell, L.W. -- Secondary diabetes : clinical considerations / Ghigo, E., Guaraldi, F., Porta, M.
  • A synthesis of the best available evidence on diagnosis, management and treatment of frequent and high-cost problems occurring in primary care, inpatient and emergency department settings. Includes the top conditions; recommends a course of action for diagnosis, disease management and drug therapy.
  • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment Of High Blood Pressure / Benjamin J. Epstein -- Hyperlipidemia / Andrew Cohen and Neil S. Skolnik -- Management of newly diagnosed atrial fibrillation: a clinical practice guideline from the American Academy of Family Physicians and the American College of Physicians / Jaya Udayasankar and Doron Schneider -- Antithrombotic therapy for venous thromboembolic disease / George P.N. Samraj -- Antithrombotic therapy for atrial fibrillation, valvular heart disease, management of elevated INRs and perioperative management / Ann Peff and Doron Schneider -- Prevention of bacterial endocarditis / Margot Boigon and Doron Schneider -- Clinical guidelines for the diagnosis and treatment of asthma / Michael Gagnon and Neil S. Skolnik -- Community acquired pneumonia and health-care associated pneumonia clinical guidelines / John Russell -- Diagnosis and management of otitis media: joint guidelines from the American Academy of Pediatrics and American Academy of Family Physicians / Richard Neill --Appropriate antibiotic use for treatment of nonspecific upper respiratory infections, rhinosinusitis, and acute bronchitis in adults / Tina H. Degnan and Neil S. Skolnik -- Group A streptococcal pharyngitis: the Infectious Disease Society of America / Mario Napoletano -- Prevention of perinatal group B streptococcal disease / Ross Albert, Neil S. Skolnik, and Richard Neill -- Adult immunizations / Brett Fissell and Neil S. Skolnik -- Rabies prevention / Doron Schneider -- Practice guidelines for the management of infectious diarrhea / Pam Fenstemacher -- Tuberculosis testing and treatment of latent infection / Pam Fenstemacher -- Sexually transmitted diseases treatment guidelines, 2006 / Neil S. Skolnik -- Updated US public health service guidelines for the management of occupational exposure to HBV, HCV, and HIV and recommendations for postexposure prophylaxis / David Gary Smith -- Screening for osteoporosis in postmenopausal women / Richard Neill --Managing abnormal cervical cytology and cervical intraepithelial neoplasia: 2001 consensus guidelines / Amy Clouse -- Dementia / William McCarberg -- Diagnosis and treatment of migraine headaches / Richard Neill -- Concussion guidelines in athletes / David Webner -- Restless legs syndrome / Matthew Clark -- Depression: pharmacological treatment / John E. Sutherland -- Diagnosis, evaluation, and treatment of the school-aged child with attention deficit hyperactive disorder / Richard Neill -- Practice guidelines for the treatment of patients with delirium / Mary Hofmann and Doron Schneider -- Panic disorder / Diane Dietzen and Doron Schneider.
  • Introduction to Evidence-Based Pathology and Laboratory Medicine -- Evidence-Based Pathology: A Stable Set of Principles for a Rapidly Evolving Specialty -- What Is Best Evidence in Pathology? -- Biostatistics 101 -- Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative Model -- Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem Cases -- Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study Results -- Power Analysis and Sample Sizes in Pathology Research -- Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies -- Decision Analysis and Decision Support Systems in Anatomic Pathology -- Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience -- Evidence-Based Cell Pathology Revisited: A Personal View -- Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical Cen -- Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based Approach -- Meta-Analysis 101 for Pathologists -- Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-Purposes -- Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into Practice -- The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory Evidence -- Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support Systems -- Evidence-Based Pathology and Tort Law: How Do They Compare?
  • Evidence Synthesis: Evolving Methodologies to Optimise Patient Care and Enhance Policy Decisions -- Barriers to Evidence Synthesis -- Systematic Review and Meta-analysis in Clinical Practice -- Diagnostic Tests -- An Introduction to Decision Analysis -- An Introduction to Cost-Effectiveness Analysis -- Evidence Synthesis Using Bayesian Belief Networks -- A Practical Introduction to Meta-analysis -- A Practical Approach to Diagnostic Meta-analysis -- Practical Examples of the Application of Decision Analysis in Healthcare -- A Practical Example of Cost-Effectiveness Analysis -- Exploring Bayesian Belief Networks Using Netica®
  • The addictions treatment field is currently undergoing a period of increased scrutiny, upheaval and change. The growing emphasis on treatment accountability and cost effectiveness is leading to major changes in standards of care. Inconsistent practices based solely on clinical intuition rather than hard scientific evidence of treatment efficacy are rapidly becoming unacceptable. Translating science-based treatments into clinical settings is an important priority in the addictions field and has been the subject of an influential Institute of Medicine report. Substance abuse treatment programs.
  • This book addresses the increasing demands on cardiology clinicians to manage complex patients with pregnancy, cancer, noncardiac surgery, systemic diseases and concurrent cardiac problems . It provides an up-to-date, detailed, evidence-based approach to key issues facing the consultant including practical clinical advice on the prevention, diagnosis, and treatment of heart disease. Evidence-Based Cardiology Consult addresses the issues specific and relevant to a cardiology consultation and focuses on cardiac issues in both the general medical patient and in specific populations. Topics covered include: The evaluation of chest pain, acute coronary syndromes, heart failure, infective endocarditis, sudden cardiac death, and imaging in cardiology consultation Cardiac problems in women, the elderly and athletes Cardiovascular disease in patients with chronic kidney disease and neurologic disease Pregnancy-related cardiac diseases Cardio-oncology, including cardiac disease resulting from chemotherapy and radiation in oncology patients. This book is a key practical resource for the management of patients with cardiac disease whether it be the primary diagnosis or as a result of other medical conditions. Therefore this is a must read for cardiology trainees and practicing cardiologists, neurologists, physicians in maternalfetal medicine, oncology, nephrology, radiology, and those who participate in preventative medicine programs.
  • The new endocrinologist: evidence-based medicine meets endocrine practice / Victor M. Montori -- A short history of evidence-based medicine / Jeanne Daly -- The philosophy of evidence-based medicine, 15 years later / Gordon H. Guyatt and Jason W. Busse -- Preparing future generations of evidence-based endocrinologists / Michael L. Green -- Finding current best evidence in clinical endocrinology / R. Brian Haynes and Cynthia J. Walker-Dilks -- Integrating evidence into clinical diagnosis / W. Scott Richardson -- Supporting evidence-based endocrine practice / Steven A. Smith and Geoffrey Gates -- Helping patients make decisions at the point of care / Annette M. O'Connor, Dawn Stacey, and France Légaré -- Incorporating evidence into health policy decisions / Eduardo Ortiz and Janelle Guirguis-Blake -- The value of observational studies in endocrinology / L. Joseph Melton III -- The value of clinical investigations in endocrinology / William L. Isley -- Systematic reviews and the Cochrane collaboration in endocrinology / Bernd Richter --Health-related quality of life of in endocrinology / Holger J. Schnemann and Elie A. Akl -- Using decision analyses in endocrinology / David Aron and Evelyn Mentari -- Clouded thinking: the misguided use of cost-effectiveness analysis and the implications for endocrine interventions / Amiram Gafni -- The value of translational research in diabetes: asking broader questions / Russell E. Glasgow, Elizabeth Bayliss, and Paul A. Estabrooks -- The patient with type 1 diabetes and hypoglycemia / Yogish C. Kudva, Teck-Kim Khoo and Peter J. Tebben -- The patient with medically complicated obesity / Kurt A. Kennel -- The patient at risk of type 2 diabetes: considering prevention / Sarah E. Capes -- The patient with type 2 diabetes and incomplete metabolic control / Sean F. Dinneen and Robert K. Semple -- The patient with diabetes using alternative medicine / Edward J. Mills and Dugald Seely -- The patient with osteoporosis / Clifford J. Rosen and Sue A. Brown -- The neuroendocrinology of medically unexplained syndromes: the example of chronic fatigue syndrome / Jason W. Busse.
  • Hypothalamic-pituitary disorders -- Thyroid disorders -- Adrenal disorders -- Metabolic bone disorders -- Reproductive disorders -- Diabetes mellitus -- Lipid disorders -- Obesity and nutrition -- Multiple endocrine neoplasia -- Carcinoid tumors -- Paraneoplastic endocrine syndromes -- Genetics.
  • The latest addition to the Evidence-Based Book series, Evidence-Based Geriatric Medicine provides non-geriatrician clinicians an overview of key topics central to the care of the older patient. This guide focuses on the management of common problems in the elderly taking into account their life situations as well as treatment of specific conditions. Leading geriatricians with expertise in evidence-based medicine utilize the best available evidence and present this information in a concise, easy-to-use, question-based format. Evidence-Based Geriatric Medicine is a unique guide to the optimum management of older patients." Fifty-five full-color narrated video clips on the companion DVD show you clinicians and patients performing the techniques described in the text.
  • Somatic dysfunction mechanisms -- Manual diagnostic procedures overview -- Treatment procedures overview -- Mechanical low back pain -- Mechanical neck and upper back pain -- Cervicogenic headache -- Temporomandibular joint dysfunction -- Shoulder pain and dysfunction -- Carpal tunnel syndrome -- Ankle sprain -- Manual medicine coding.
  • "This handbook delivers the assistance you need to provide timely and effective, evidence-based consultations for a range of commonly encountered clinical situations. This book will help you: navigate the most common clinical scenarios requiring medical consultation by reviewing 20-25 clinical questions for each patient type; locate evidence-based answers for each question, collected from the latest clinical findings; and find the information you need quickly thanks to a user-friendly format."--BOOK JACKET.
  • How to search for evidence -- Epidemiology -- Clinical manifestations -- Laboratory tests -- Rational antibiotic use -- Adjunctive treatment -- Bacterial meningitis -- Respiratory tract infections -- Osteomyelitis and septic arthritis -- Urinary tract infections -- Necrotizing enterocolitis and gastrointestinal infections -- Eye infections -- Skin and soft tissue infections -- Bacterial infections -- Mycoplasmas -- Fungal infections -- Viral infections -- Other congenital infections -- Breast milk -- Surveillance -- Infection control -- Developing countries -- Prevention of neonatal infections -- Neonatal antimicrobials.
  • With the aging population ever growing, healthcare for persons suffering from stroke and related illnesses is increasingly important. Evidence-Based Nursing Care in Stroke and Neurovascular Conditions provides a comprehensive and practical guide for novice, experienced and advanced practice nurses working with patients suffering from stroke and other neurovascular conditions. With a focus specifically on neurovascular disorders, this highly detailed text offers easy-to-find information on evidence-based care guidelines.
  • Dr. James Wright, Associate Editor for the Journal of Bone and Joint Surgery, presents this landmark publication and novel approach to orthopaedic problems and solutions. This new, evidence-based reference examines clinical options and discusses relevant research evidence to provide you with expert recommendations for best practice. The consistent chapter format and featured summary tables provide "at-a-glance" access to the evidence-based literature and clinical options. Leading authorities contribute their expertise so you can apply the most effective clinical solutions to the persistent questions you encounter in your practice.
  • This book is updated with evidence from the latest published reviews and is more clinically focused, with an emphasis on application of the trial findings. With increased coverage of trials in the area of supportive care for pediatric cancer patients, each chapter opens with a clinical question and concludes with a summary on the trial findings from an expert commentator.
  • Fulltext ClinicalKey
    Pt. 1. Introduction. What is evidence-based physical diagnosis? -- Pt. 2. Understanding the evidence. Diagnostic accuracy of physical findings -- Using the tables in this book -- Reliability of physical findings -- Pt. 3. General appearance of the patient. Mental status examination -- Stance and gait -- Jaundice -- Cyanosis -- Anemia -- Hypovolemia -- Protein-energy malnutrition and weight loss -- Obesity -- Cushing syndrome -- Pt. 4. Vital signs. Pulse rate and contour -- Abnormalities of pulse rhythm -- Blood pressure -- Temperature -- Respiratory rate and abnormal breathing patterns -- Pulse oximetry -- Pt. 5. Head and neck. The pupils -- Diabetic retinopathy -- Hearing -- Thyroid and its disorders -- Meninges -- Peripheral lymphadenopathy -- Pt. 6. the lungs. Inspection of the chest -- Palpation and percussion of the chest -- Auscultation of the lungs -- Ancillary tests -- Pt. 7. Selected pulmonary disorders. Pneumonia -- Chronic obstructive lung disease -- Pulmonary embolism -- Pleural effusion -- Pt. 8. The heart. Inspection of the neck veins -- Percussion of the heart -- Palpation of the heart -- Auscultation of the heart: general principles -- The first and second heart sounds -- The third and fourth heart sounds -- Miscellaneous heart sounds - Heart murmurs: general principles -- Pt. 9. Selected cardiac disorders. Aortic stenosis -- Aortic regurgitation -- Miscellaneous heart murmurs -- Disorders of the pericardium -- Congestive heart failure -- Coronary artery disease -- Pt. 10. Abdomen. Inspection of the abdomen -- Palpation and percussion of the abdomen -- Abdominal pain and tenderness -- Auscultation of the abdomen -- Pt. 11. Extremities. Peripheral vascular disease -- The diabetic foot -- Edema and deep vein thrombosis -- Examination of the musculoskeletal system -- Pt. 12. Neurologic examination. Visual field testing -- nerves of the eye muscles (III, IV, and VI): approach to diplopia -- Miscellaneous cranial nerves -- Examination of the motor system: approach to weakness -- Examination of the sensory system -- Examination of the reflexes -- Disorders of the nerve roots, plexuses, and peripheral nerves -- Coordination and cerebellar testing -- Pt. 13. Selected neurologic disorders. Tremor and Parkinson disease -- Hemorrhagic versus ischemic stroke -- Acute vertigo and imbalance -- Examination of nonorganic neurologic disorders -- Pt. 14. Examination in the intensive care unit. Examination of patients in the intensive care unit -- Appendix. Likelihood ratios, confidence intervals, and pretest probability.
  • pt. I. Evidence-Based and Comparative Effectiveness Analysis -- 1. Fundamentals: Evidence-Based Practice in Complementary and Alternative Medicine: Perspectives, Protocols, Problems, and Potentials / Francesco Chiappelli -- pt. II. Evidence-Based Medicine and Ayurveda -- 2. Transforming Ayurveda: Stepping into the Realm of Evidence-Based Practice / Ram Harsh Singh -- 3. Diet and Nutrition Concepts in Ayurveda: Gleaming into Opportunities for Evidence-Based Applications in Health Care / Rajiv Rastogi -- 4. Clinical Evidence in the Tradition of Ayurveda / P. Ram Manohar -- 5. Evidence-Based Traditional Persian Medicine / Francesco Chiappelli -- pt. III. Substantiating Ayurvedic Theory and Practice Toward Evidence-Base -- 6. Prakriti Analysis in Ayurveda: Envisaging the Need of Better Diagnostic Tools / Sanjeev Rastogi -- 7. Panchakarma: Ayurvedic Detoxification and Allied Therapies---Is There Any Evidence? / Ingebritt Ziegler -- 8. Gut and Joint Interconnections: A Reappraisal to Ayurvedic Understanding of Joint Diseases / Ranjana Rastogi -- 9. Ayurvedic Approach to Cardiovascular Diseases: Delineating the Literary and Clinical Evidences / P.S. Srivastav -- 10. Rasayana Therapy and Rejuvenation / Sanjeev Rastogi -- 11. Translational Effectiveness in Ayurvedic Medicine: Implications for Oral Biology and Medicine / Francesco Chiappelli -- pt. IV. Towards Future Perspectives of Evidence-Based Ayurveda -- 12. Safety Aspects of Ayurvedic Drugs / Arun Gupta -- 13. Toward Evidence-Based Practice of Ayurveda: Extrapolating the Challenges in the Current Decade / Sanjeev Rastogi.
  • The ethical debate on evidence-based medicine - introduction to the volume -- Regulating health care. The development of guidelines in medical practice and health policy -- Evidence-based medicine and power shifts in health care systems -- Beyond legitimate science: the case for policy-related science -- Teaching evidence-based medicine -- Evidence-based medicine and clinical guidelines in cardiology. Promoting science, practice, or bureaucracy? -- Are particular patients disadvantaged by EBM? Focus on frail elderly patients -- Evidence-based medicine in mental health: towards better and fairer treatment? -- Current epistemological problems in evidence-based medicine -- Coordinating the norms and values of medical research, medical practice and patient worlds. The ethics of evidence-based medicine in 'boundary fields of medicine' -- Research ethics and evidence-based medicine -- Clinical evaluative research: which patients benefit, how and when? A contribution to a European discussion -- Defining a proper background for discussing evidence-based medicine -- Evidence-based medicine and equity: the exclusion of disadvantaged groups -- The role of formal outcome evaluations in health policy making: a normative perspective -- The usefulness of formal outcome evaluations in health policy making: looking for the baby in the bathwater -- Evidence-based medicine and managed care -- Recommendations from the evibased project.
  • 1. Evidence-Based Practice Parameters : The Approach of the American Society of Anesthesiologists -- 2. Update on Preprocedure Testing -- 3. Is a Preoperative Screening Clinic Cost-Effective? -- 4. Who Should Have a Preoperative 12-Lead Electrocardiogram? -- 5. Is Routine Preoperative Pregnanc y Testing Necessary? -- 6. What Are the Risk Factors for Perioperative Stroke? -- 7. Should We Delay Surgery in the Patient with Recent Cocaine Use? -- 8. Should All Antihypertensive Agents Be Continued before Surgery? -- 9. What Is the Optimal Timing for Smoking Cessation? -- 10. Which Patient Should Have a Preoperative Cardiac Evaluation (Stress Test)? -- 11. Should Patients with Stable Coronary Artery Disease Undergo Prophylactic Revascularization before Noncardiac Surgery? -- 12. What Are the Role and Management of Percutaneous Coronary Intervention for Noncardiac Surgery? -- 13. How Should We Prepare the Patient with a Pacemaker/Implantable Cardioverter-Defibrillator? -- 14. When Should Pulmonary Function Tests Be Performed Preoperatively? -- 15. Does the Airway Examination Predict Difficult Intubation? -- 16. Is There a Best Approach for Patients with Difficult Airways : Regional versus General Anesthesia? -- 17. What Is the Optimal Airway Management in Patients Undergoing Gastrointestinal Endoscopy? -- 18. Is There a Best Approach to Induction of Anesthesia in Emergent Situations? -- 19. Do Inhalational Agents Have Beneficial or Harmful Effects on Ischemia-Reperfusion Injury? -- 20. Does Anesthetic Choice Affect Surgical and Recovery Times? -- 21. What Are the Benefits of Different Ventilatory Techniques? -- 22. Is There an Optimal Perioperative Hemoglobin Level? -- 23. When Are Platelets and Plasma Transfusions Indicated? -- 24. What Drugs Decrease Perioperative Bleeding? -- 25. Does Perioperative Hyperglycemia Increase Risk? Should We Have Aggressive Glucose Control Perioperatively? -- 26. When and Why Should Perioperative Glucocorticoid Replacement Be Administered? -- 27. Does the Choice of Fluid Matter in Major Surgery? -- 28. What Works in a Patient with Acute Respiratory Distress Syndrome? -- 29. What Actions Can Be Used to Prevent Peripheral Nerve Injury? 30. What Is the Best Means of Preventing Perioperative Renal Injury? -- 31. Does Nitrous Oxide Affect Outcomes? -- 32. Are Alpha-2 Agonists Effective in Reducing Perioperative Cardiac Complications in Noncardiac Surgery? -- 33. What Is the Role of Ketamine in Perioperative Management? -- 34. Should Hypothermia Be Used Routinely after Intraoperative Cardiac Arrest? -- 35. Which Are the Best Techniques for Reducing the Incidence of Postoperative Deep Vein Thrombosis? -- 36. Are There Special Techniques in Obese Patients? -- 37. Is There an Ideal Approach to the Patient Susceptible to Malignant Hyperthermia? -- 38. What Is the Best Strategy for Prevention of Postoperative Nausea and Vomiting? -- 39. How Should Beta-Blockers Be Used Perioperatively? -- 40. How Can We Prevent Postoperative Cognitive Dysfunction? -- 41. Do Intensive Care Specialists Improve Patient Outcomes? -- 42. Fast-Track Cardiac Anesthesia : What Works Best for Safety and Efficacy? -- 43. Can We Prevent Recall during Anesthesia? -- 44. Are Patients with Sleep Apnea Appropriate for Ambulatory Surgery? -- 45. What Criteria Should Be Used for Discharge after Outpatient Surgery? -- 46. What Must I Consider in Order to Safely Anesthetize Someone in the Office Setting? -- 47. Is Propofol Safe If Given by Nonanesthesia Providers? -- 48. Aspiration : Is There an Optimal Management Strategy? -- 49. Nonsteroidal Antiinflammatory Drugs, Antiplatelet Medications, and Spinal Axis Anesthesia -- 50. DVT Prophylaxis with Heparin and Heparin-Like Drugs (UH, LMWH, Fondaparinux, and Rivaroxaban) Used in Combination with Neuraxial Anesthesia and Deep Plexus Blocks -- 51. Is Regional Anesthesia Appropriate for Outpatient Surgery? -- 52. What Is the Best Technique for Hip Surgery? -- 53. Does Intraoperative Regional Anesthesia Decrease Perioperative Blood Loss? -- 54. What Is the Optimal Management of Postdural Puncture Headache? -- 55. Should Ultrasound Guidance Be the Standard of Practice for Peripheral Nerve Blockade? -- 56. Should Regional Anesthesia Be Used for Orthopedic Trauma Patients? -- 57. What Is the Best Method of Diagnosing Perioperative Myocardial Infarction? -- 58. Does Neurologic Electrophysiologic Monitoring Affect Outcome? -- 59. Is Regional Superior to General Anesthesia for Infrainguinal Revascularization? -- 60. Is There a Best Technique to Decrease Blood Loss and Transfusion after Coronary Artery Bypass Grafting? -- 61. Should Thoracic Epidural/Spinal Analgesia be Used for Coronary Artery Bypass Grafting? -- 62. Is There a Best Technique in the Patient with Increased Intracranial Pressure? -- 63. What Works for Brain Protection? -- 64. Anesthesia for Cesarean Delivery : Regional or General? -- 65. When Should a Combined Spinal-Epidural Be Used? 66. Does Labor Analgesia Affect Labor Outcome? -- 67. Does Anesthesia Increase the Risk to the Parturient Undergoing Nonobstetric Surgery? -- 68. How Young Is the Youngest Infant for Outpatient Surgery? -- 69. Should a Child with a Respiratory Tract Infection Undergo Elective Surgery? -- 70. When Should Regional Anesthesia Be Used in Pediatric Patients? -- 71. Optimal Postoperative Analgesia -- 72. Is Pre-Emptive Analgesia Clinically Effective?
  • Evidence-Based Practice of Critical Care, edited by Drs. Clifford S. Deutschman and Patrick J. Neligan, provides objective data and expert guidance to help answer the most important questions challenging ICU physicians today. It discusses the clinical options, examines the relevant research, and presents expert recommendations on everything from acute organ failure to prevention issues. An outstanding source for "best practices" in critical care medicine, this book is a valuable framework for translating evidence into practice. It also provides access to the full text online, with regular updates to emerging clinical evidence. Gain valuable evidence-based recommendations on key topics such as acute organ failure, infection, sepsis and inflammation, and prevention issues pointing the way to the most effective approaches. Get an overview of each question, an outline of management options, a review of the relevant evidence, areas of uncertainty, existing management guidelines, and authors₂ recommendations. Navigate a full range of challenges from routine care to complicated and special situations. Find the information you need quickly with tables that summarize the available literature and recommended clinical approaches. Stay current on the latest advances in the field with full-text, online access that includes regular updates to emerging clinical evidence.
  • 1. How Should Opioids Be Started and Titrated in Routine Outpatient Settings? -- 2. How Should Opioids Be Started and Titrated in Hospital or Inpatient Settings? -- 3. How Should Patient-Controlled Analgesia Be Used in Patients With Serious Illness and Those Experiencing Postoperative Pain? -- 4. How Should Opioids Be Used to Manage Pain Emergencies? -- 5. What Principles Should Guide Oral, Transcutaneous, and Intravenous Opioid Dose Conversions? -- 6. Which Opioids Are Safest and Most Effective in Renal Failure? -- 7. How Should Methadone Be Started and Titrated in Opioid-Naïve and Opioid-Tolerant Patients? -- 8. What Special Considerations Should Guide the Safe Use of Methadone? -- 9. When Should Corticosteroids Be Used to Manage Pain? -- 10. When Should Nonsteroidal Antiinflammatory Drugs Be Used to Manage Pain? -- 11. What Is Neuropathic Pain? How Do Opioids and Nonopioids Compare for Neuropathic Pain Management? -- 12. Should Bisphosphonates Be Used Routinely to Manage Pain and Skeletal Complications in Cancer? -- 13. Should Bisphosphonates Be Used Routinely to Manage Pain and Skeletal Complications in Other Conditions? -- 14. When Should Radiotherapy Be Considered for Pain Management and What Principles Should Guide the Consideration of Limited-Fraction Versus Full-Dose Radiotherapy? -- 15. When Should Radiopharmaceuticals Be Considered for Pain Management? -- 16. What Principles Should Guide the Prescribing of Opioids for Non-Cancer-Related Pain? -- 17. What Approaches Should Be Used to Minimize Opioid Diversion and Abuse in Palliative Care? -- 18. When Should Epidural or Intrathecal Opioid Infusions and Pumps Be Considered for Pain Management? -- 19. When Should Nerve Blocks Be Used for Pain Management? -- 20. What Interventions Are Effective for Managing Dyspnea in Cancer? -- 21. What Is the Role of Opioids in Treatment of Refractory Dyspnea in Advanced Chronic Obstructive Pulmonary Disease? -- 22. What Nonopioid Treatments Should Be Used to Manage Dyspnea Associated With Chronic Obstructive Pulmonary Disease? -- 23. What Interventions Are Effective for Managing Dyspnea in Heart Failure? -- 24. What Medications Are Effective in Preventing and Relieving Constipation in the Setting of Opioid Use? -- 25. How Should Medications Be Initiated and Titrated to Reduce Acute and Delayed Nausea and Vomiting in the Setting of Chemotherapy? -- 26. How S hould Medications Be Initiated and Titrated to Prevent and Treat Nausea and Vomiting in Clinical Situations Unrelated to Chemotherapy? -- 27. What Interventions Are Effective for Relieving Acute Bowel Obstruction in Cancer and Other Conditions? -- 28. What Medications Are Effective in Improving Anorexia and Weight Loss in Cancer? -- 29. What Therapeutic Strategies Are Effective in Improving Anorexia and Weight Loss in Nonmalignant Disease? -- 30. When Should Enteral Feeding by Percutaneous Tube Be Used in Patients With Cancer and in Patients With Non-Cancer-Related Conditions? -- 31. When Should Parenteral Feeding Be Considered for Patients With Cancer and for Patients With Non-Cancer-Related Conditions? -- 32. How Does One Assess for Psychiatric Illness in Patients With Advanced Disease? -- 33. What Treatments Are Effective for Depression in the Palliative Care Setting? -- 34. What Treatments Are Effective for Anxiety in Patients With Serious Illness? -- 35. What Is Delirium? -- 36. What Are Effective Pharmacological Treatments for Delirium? -- 37. What Nonpharmacological Treatments Are Effective for Delirium? -- 38. What Are the Differences When Treating a Patient at the End of Life With Delirium (Terminal Delirium)? -- 39. How Do Symptoms Change for Patients in the Last Days and Hours of Life? -- 40. What Is Known About Prognostication in Advanced Illness? -- 41. What Is a Useful Strategy for Estimating Survival in Palliative Care Settings for Persons With Advanced Cancer? -- 42. What Is a Useful Strategy for Estimating Survival for Persons With Advanced Non-Cancer-Related Illness in Palliative Care Settings? -- 43. What Are the Key Elements to Having a Conversation About Setting Goals and Communicating Serious News? -- 44. What Do Palliative Care Clinicians Need to Know About Teaching Communication? -- 45. What Are Advance Care Plans and How Are They Different From Advance Directives? -- 46. What Elements Are Essential to Effective Advance Care Planning? -- 47. What Is the Evidence That Advance Care Plans Change Patient Outcomes? -- 48. What Is the Role for Palliative Care in Patients With Advanced Cancer? -- 49. What Is the Clinical Course of Advanced Cancer? -- 50. What Is the Relationsh ip Between Patient Performance Status and Ability to Offer Chemotherapeutic Treatments? -- 51. What Is the Clinical Course of Advanced Dementia? -- 52. What Are Appropriate Palliative Interventions for Patients With Advanced Dementia? -- 53. What Is the Clinical Course of Advanced Liver Disease and What Symptoms Are Associated With It? -- 54. What Special Considerations Are Needed for Treating Patients With Chronic Liver Disease? -- 55. What Is the Role of Palliative Care in Stroke? -- 56. What Special Considerations Are Needed for Individuals With Amyotrophic Lateral Sclerosis, Multiple Sclerosis, or Parkinson Disease? -- 57. What Is the Clinical Course of Advanced Heart Failure and How Do Implanted Cardiac Devices Alter This Course? -- 58. What Is Chronic Critical Illness and What Outcomes Can Be Expected? -- 59. What Special Considerations Are Needed in Patients With Head and Neck Cancer? -- 60. What Special Considerations Are Needed in Treating Symptoms in Patients With End-Stage Renal Disease? -- 61. How Is the Patient Who Stops Dialysis Best Managed? -- 62. Which Patients With End-Stage Renal Disease Should Not Be Started on Dialysis? -- 63. What Is Frailty? -- 64. What Are the Special Needs of Patients With Frailty? -- 65. What Are Special Considerations for Treating Pediatric Patients and Their Families? -- 66. What Are the Signs and Symptoms of Spinal Cord Compression? -- 67. What Are the Best Pharmacological and Surgical Treatments for Patients With Spinal Cord Compression? -- 68. What Techniques Can Be Used in the Hospital or Home Setting to Best Manage Uncontrollable Bleeding? -- 69. What Can Be Done for Patients With Crisis Dyspnea? -- 70. What Are the Arguments That Show That Palliative Care Is Beneficial to Hospitals? -- 71. What Are the Arguments That Show Outpatient Palliative Care Is Beneficial to Medical Systems? -- 72. What Is the Eff ect of Serious Illness on Caregivers? -- 73. What Can Be Done to Improve Outcomes for Caregivers of Patients With Serious Illness? -- 74. What Is Prolonged Grief Disorder and How Can Its Likelihood Be Reduced? -- 75. What Are the Eligibility Criteria for Hospice? -- 76. In What Settings Can Hospice Be Provided? -- 77. What Models Exist for Delivering Palliative Care and Hospice in Nursing Homes? -- 78. How Can Palliative Care Be Integrated Into Home-Based Primary Care Programs? -- 79. What New Models Exist for Ambulatory Palliative Care? -- 80. What New Models Exist for Palliative Care in the Emergency Department? -- 81. What Are Sources of Spiritual and Existential Suffering for Patients With Advanced Disease?
  • Introduction: research synthesis in evidence-based clinical decision-making -- Overview, strengths, and limitations of systematic reviews and meta-analyses -- Understanding and interpreting systematic review and meta-analysis results -- Making evidence-based decisions in nursing -- A model for implementing evidence-based decisions in dental practice -- Evidence-based decisions in human immunodeficiency virus infection and cardiac disease -- Bringing evidence basis to decision making in complementary and alternative medicine (CAM): prakriti (constitution) analysis in Ayurveda -- Evidence-based clinical decisions in oral surgery -- Evidence-based issues in maxillofacial trauma -- Strengths and limitations of the evidence-based movement aimed to improve clinical outcomes in dentistry and oral surgery -- Evidence-based decisions for pharmacological management of alcoholic liver disease and alcohol dependence -- Temporomandibular joint disorders, a bibliometric evidence-based approach to analysis -- The efficacy of horizontal and vertical bone augmentation procedures for dental implants: a Cochrane systematic review -- Evidence-based medicine: what does it mean and where are we going? -- Future avenues of research synthesis for evidence-based clinical decision making.
  • Evidence-based practices in autism: Where we started / Brian Reichow and Fred R. Volkmar -- Development, procedures, and application of the evaluative method for determining evidence-based practices in autism / Brian Reichow -- On the reliability and accuracy of the evaluative method for identifying evidence-based practices in autism / Domenic V. Cicchetti -- evidence-based treatment of behavioral excesses and deficits for individuals with autism spectrum disorders / Michael D. Powers, Mark J. Palmieri, Kristen S. D'Eramo, and Kristen M. Powers -- Evidence-based treatments in communication for children with autism spectrum disorders / Patricia A. Prelock, Rhea Paul, and Elizabeth M. Allen -- Treatments to increase social awareness and social skills / Suzannah J. Ferraioli and Sandra L. Harris -- Cognitive behavioral therapy in high-functioning autism: Review and recommendations for treatment development / Jeffrey J. Wood, Cori Fujii, and Patricia Renno -- Psychopharmacology in children with PDD: Review of current evidence / Lawrence Scahill and Susan Griebell Boorin -- Interventions that address sensory dysfunction for individuals with Autism Spectrum Disorders: Preliminary evidence for the superiority of sensory integration compared to other sensory approaches / Roseann C. Schaaf -- Dietary, complementary, and alternative therapies / Susan L. Hyman and Susan E. Levy -- The role of adaptive behavior in evidence-based practices for ASD: Translating intervention into functional success / Katherine D. Tsatsanis, Celine Saulnier, Sara S. Sparrow, and Domenic V. Cicchetti -- Practicing evidence-based practices / Ruth Blennerhassett Eren and Pamela Owen Brucker -- The implementation of evidence-based practices in public schools / Peter Doehring and Vincent Winterling -- Evidence-based practices in autism: Where we are now and where we need to go / Fred R. Volkmar, Brian Reichow, and Peter Doehring.
  • Covers the spectrum of procedural dermatology, including skin cancer surgery, laser techniques, fillers and neurotoxins, minimally invasive cosmetic surgery, and emerging procedures.
  • The challenge of providing mental health services in schools -- Evidence-based tier 1, tier 2, and tier 3 mental health interventions in schools -- Strengthening school-counseling interventions -- Affect education at tiers 1, 2, and 3 -- Importance of emotion regulation training for children and adolescents -- Emotion regulation training at tiers 1, 2, and 3 -- Support for the use of CBT in schools -- Preparing young and/or disabled children to benefit from CBT in school-based settings -- CBT in schools -- Sustainability, current programs, and a look to the future.
  • Part 1. Early artistic contributions to the neurosciences -- part 2. Neuroscientists with artistic talents and artists on the neurosciences -- part 3. Some great artists and their neurological disorders.
  • This is a basic book on evidence-based medicine (EBM). It starts with an introduction to the topic. It outlines the relationship between EBM and research and quality of care. Then It goes on to cover the most commonly used modules of EBM, i.e. therapy, diagnosis, prognosis and meta-analysis. Each module starts with an introduction to fundamental concepts, and description of the related research process, and then follows the critical appraisal of related type of research artcle. At the end, it covers the different systems of grading of level of evidence and strength of recommendations. The book also has three examples of critical appraisal on diagnosis, therapy, and meta-analysis.
  • Fundamental Implications for Clinical Practice -- Translational Effectiveness in the Context of Translational Science -- Comparative Effectiveness Analysis and Evidence-Based Decisions -- Methodology I: The Best Available Evidence -- Methodology II: Sampling and Assessment of the Evidence -- Methodology III: Systematic Evaluation of the Statistical Analysis: Data Analysis in Research Synthesis -- Optimizing Clinical Practice-Based Patient-Centered Outcomes Research -- Getting and Understanding Data -- Obtaining Data -- Describing and Analyzing Data -- Translational Effectiveness Analysis -- Optimizing Clinical Outcomes by Individualizing Observations -- Evaluation in Patient-Centered Outcomes Research -- Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research.
  • Evidence-based medicine for neurosurgeons: introduction and methodology / M.E. Linskey -- Evaluation of epidemiologic evidence for primary adult brain tumor risk factors using evidence-based medicine / J.L. Fisher ... [et al.] -- Benign adult brain tumors: an evidence-based medicine review / M. Aghi, F.G. Barker, II -- Pediatric neurosurgery / C.O. Maher, A.A. Cohen-Gadol, C. Raffel -- Cerebrovascular-endovascular / K.M. Cockroft, R.H. Rosenwasser -- Evidence-based guidelines in lumbar spine surgery / D.K. Resnick, M.C. Groff -- Spine: minimally invasive techniques / P.C. Gerszten, W.C. Welch -- An evidence-based medicine review of stereotactic radiosurgery / B.E. Pollock -- Evidenced-based guidelines for traumatic brain injuries / D.W. Marion -- Treatment of chronic pain with neurostimulation / J.K. Birknes, A. Sharan, A.R. Rezai.
  • Current theories and treatment of depression -- Cognitive theory of depression -- Hypnosis and hypnotherapy -- Circular feedback model of depression -- Clinical implications and empirical evidence -- Cognitive hypnotherapy case formulation -- First aid for depression -- Cognitive behavior therapy -- Hypnotherapy -- Cognitive hypnotherapy -- Developing antidepressive pathways -- Breaking ruminative pattern -- Behavioral activation therapy -- Improving social skills -- Mindfulness and acceptance -- Relapse prevention -- Future directions.
  • This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding numerous references to make this book the most current and thorough treatment of evidence-based critical care available. The handbook enables the clinician to find the evidence to support or refute an intervention and to help choose the most appropriate, cost-effective treatment. The analysis of treatment strategies is presented by organ system, and the handbook also covers miscellaneous ICU topics (such as sedation, toxicology, radiology, and sepsis) based on the most frequently found and difficult to solve problems in ICU patient management.
  • Skin cancer -- Central nervous system -- Malignant and benign diseases of the eye and orbit -- Cancer of the ear -- Nasopharyngeal cancer -- Nasal cavity and paranasal sinus cancer -- Oropharyngeal cancer -- Cancer of the lip and oral cavity -- Larynx and hypopharynx cancer -- Salivary gland tumors -- Thyroid cancer -- Unusual neoplasms of the head and neck -- Management of the neck and unknown primary of the head and neck -- Small cell lung cancer -- Non-small cell lung cancer -- Mesothelioma and thymic tumors -- Breast cancer -- Esophageal cancer -- Gastric cancer -- Pancreatic cancer -- Hepatobiliary cancer -- Colorectal cancer -- Anal cancer -- Renal call carcinoma -- Bladder cancer -- Prostate cancer -- Cancer of the penis -- Testicular cancer -- Cervical cancer -- Endometrial cancer -- Ovarian cancer -- Vaginal cancer -- Vulvar cancer -- Urethral cancer -- Hodgkin's lymphoma -- Non-Hodgkin's lymphoma -- Cutaneous lymphomas -- Multiple myeloma and plasmacytoma -- Bone tumors -- Soft-tissue sarcoma -- Pediatric (Non-CNS) tumors -- Palliation and benign conditions -- Clinical radiobiology and physics.
  • This title discusses obesity and shows how it is a major risk factor for a variety of cardiovascular, cardiopulmonary, endocrinologic, metabolic, musculoskeletal, and behavioral disorders.
  • "his book, written by expert surgeons, offers a comprehensive and up-to-date overview of all aspects of laparoscopic cholecystectomy. Coverage includes the indications for surgery, anesthesia, establishment of pneumoperitoneum, surgical technique, and the prevention and management of complications. Performance of laparoscopic cholecystectomy in the specific contexts of biliary tree stones and acute cholecystitis is described. Extensive reference is made to the latest clinical evidence, and the real benefits of the laparoscopic approach, for example in terms of outcomes and day surgery, are carefully assessed. New technologies, including SILS, NOTES, robotic surgery, and miniaturized instruments, are reviewed. The learning curve and training are also extensively discussed, and an individual chapter is devoted to the views of international experts in the field. Some 20 years after the National Institutes of Health Consensus Conference first published recommendations regarding indications for laparoscopic cholecystectomy, it remains the gold standard approach and continues to evolve."--Publisher's website.
  • This book is a comprehensive analysis of the definitions, concepts, and recent research on malingering, feigning, and other response biases in psychological injury/ forensic disability populations. It presents a new model of malingering and related biases, and develops a "diagnostic" system based on it that is applicable to PTSD, chronic pain, and TBI. Included are suggestions for effective practice and future research based on the literature reviews and the new systems, which are useful also because they can be used readily by psychiatrists as much as psychologists.
  • Here's all the guidance you need to write clear, concise, safe, and effective medical orders! Whether you've had training in order writing or not, and whether you use an electronic order system or not, this handy guide offers you strategies, templates, decision-making guidelines, and a systematic, evidence-based approach to reinforce what you know ... simplify and improve communication with your colleagues ... and thus reduce confusion, unnecessary steps, and costly mistakes. Includes sample admitting orders for almost 100 illnesses and conditions. Offers valuable guidelines for revising original orders. Provides special procedures for handling verbal orders given in fast-paced, intense situations. Thoroughly reviewed by a large number of experienced clinicians for optimal "real-world" practicality.
  • Clinically relevant carbohydrate metabolism -- Clinically relevant fat metabolism -- Clinically relevant protein metabolism -- Overview of clinically relevant micronutrient metabolism -- Diet, weight regulation, and obesity -- Diet, diabetes mellitus, and insulin resistance -- Diet, atherosclerosis, and ischemic heart disease -- Diet and hypertension -- Diet and hemostasis -- Diet and cerebrovascular and peripheral vascular disease -- Diet and immunity -- Diet and cancer -- Diet and hematopoiesis: nutritional anemias -- Diet, bone metabolism, and osteoporosis -- Diet and respiratory diseases -- Diet and renal disease -- Diet and hepatobiliary disease -- Diet and common gastrointestinal disorders -- Diet, dyspepsia, and peptic ulcer disease -- Diet and rheumatologic disease -- Diet and neurologic disorders -- Diet and dermatoses -- Diet and wound healing -- Food allergy and intolerance -- Eating disorders -- Malnutrition and cachexia -- Diet, pregnancy, and lactation -- Diet and the menstrual cycle -- Diet and early development: pediatric nutrition -- Diet and adolescence -- Diet and senescence -- Ergogenic effects of foods and nutrients: diet and athletic performance -- Endocrine effects of diet: phytoestrogens -- Diet, sleep-wake cycles, and mood -- Diet and cognitive function -- Diet and vision -- Diet and dentition -- Hunger, appetite, taste, and satiety -- Health effects of chocolate -- Health effects of ethanol -- Health effects of coffee -- Macronutrient food substitutes -- Vegetarianism, veganism, and macrobiotic diets -- Culture, evolutionary biology, and the determinants of dietary preference -- Dietary recommendations for health promotion and disease prevention -- Models of behavior modification for diet and activity patterns and weight management -- Dietary counseling in clinical practice.
  • Evidence-based medicine is the future of orthopedic surgery. The escalating costs of medical care drive the need for physicians to base clinical decisions on data in order to provide optimal care to every patient. Orthopedic Traumatology: An Evidence-Based Approach provides readers a model for evidence-based decision making in orthopedic trauma. Renowned orthopedic trauma surgeons describe interesting clinical scenarios, give expert opinions on management, and include relevant imaging to create a complete picture of each fascinating case. Useful for residents and practicing physicians alike, Orthopedic Traumatology is a unique guide to orthopedic trauma and evidence-based medicine.
  • Introduction to positive relationships: evidence-based practice across the world / Sue Roffey -- Wellbeing and resilience in young people and the role of positive relationships / Toni Noble and Helen McGrath -- Peaceful and compassionate futures: positive relationships as an antidote to violence / Robyn Hromek and Angela Walsh -- Learning about relationships / Gretchen Brion-Meisels and Stephanie M. Jones -- Positive couple relationships: the evidence for long-lasting relationship satisfaction and happiness / Vagdevi Meunier and Wayne Baker -- Positive parent-child relationships / Kimberly O'Brien and Jane Mosco -- Promoting positive outcomes for children experiencing change in family relationships / Emilia Dowling and Diana Elliott -- Friendships: the power of positive alliance / Karen Majors -- Developing positive relationships in schools / Sue Roffey -- Positive relationships at work / Sue Langley -- Positive professional relationships / Elizabeth Gillies -- Positive mentoring relationships: nurturing potential / Ann M. Brewer -- Spirited leadership: growing leaders for the future / Hilary B. Armstrong -- Positive community relations: border crossings and repositioning the "other" / Florence E. McCarthy and Margaret H. Vickers -- Positive relations between members of groups with divergent beliefs and cultures / Zalman Kastel -- Conflict and confrontation / Lois Edmund -- The repair and restoration of relationships / Peta Blood.
  • Pt.1. Introduction -- Pt.2. Observational Studies -- Pt.3. Step-by-Step Biostatistics of a Clinical Trial -- Pt.4. Additional Concepts in Biostatistics.
  • Evidence-based physiotherapy : what, why and how? -- What do I need to know? -- What constitutes evidence? -- Finding the evidence -- Can I trust this evidence? -- What does this evidence mean for my practice? -- Clinical guidelines as a resource for evidence-based physiotherapy -- When and how should new therapies be introduced into clinical practice? -- Making it happen -- Am I on the right track?
  • Ways we see, learn, and practice medicine today : paradigms of what we are doing -- How physicians and other health professionals really (or should) think -- Reasoning in step-by-step clinical work and care : risk, diagnosis, treatment, prognosis -- Clinical and community medicine decision making -- How physicians communicate with themselves, their patients, and others : clinical communication and its vehicles -- Conclusions (with a short recapitulation) : welcome to the world of reasoned and evidence-based medicine.
  • This book contains a collection of critical reviews on the expression of biologically functional proteins in Leishmania and Trypanosoma, which was written by renowned researchers on this field. Species belonging to these trypanosomatids genera are etiological agents of leishmaniasis, Chagas' disease and sleeping sickness that are extremely debilitating human infection diseases, which remain a major health problem especially in countries from Latin America, Africa and Middle East. Substantiating the problem, the currently accepted drugs for these diseases are quite unsatisfying due to their low efficacy and high toxicity. In order to solve these real problems, several research groups around the world have become involved in the study and identification of novel potential targets in the trypanosomatid cell. Since proteins are key macromolecules involved in crucial metabolic processes of all living cells, studies have focused on the expression of specific proteins produced by Leishmania and Trypanosoma by means of different biochemical, molecular and proteomic approaches in order to explore them as targets for understanding the parasite life cycle and developing new strategies against trypanosomiasis. With these proposals in mind, the book "Proteins and Proteome of Leishmania and Trypanosoma" encompasses (i) an integrated view about the biochemistry of parasites belonging to the Leishmania and Trypanosoma genera; (ii) an updated review on the expression of biologically relevant proteins by human pathogenic trypanosomatids and their possible role in the interaction with host cells/molecules as well as a target for development of both alternative chemotherapies and vaccine; and (iii) several pictures, diagrams and tables that can be used to illustrate both undergraduate and postgraduate teaching as well as scientific lectures, being a useful resource for students and researchers.
  • Front Matter -- Colour Plates -- Factors of High-Risk Pregnancy. Overview of High-Risk Pregnancy / John T Queenan, Catherine Y Spong, Charles J Lockwood -- Maternal Nutrition / Edward R Newton -- Alcohol and Substance Abuse / William F Rayburn -- Environmental Agents and Reproductive Risk / Laura Goetzl -- Genetics. Genetic Screening for Mendelian Disorders / Deborah A Driscoll -- Screening for Congenital Heart Disease / Lynn L Simpson -- First- and Second-Trimester Screening for Fetal Aneuploidy and Neural Tube Defects / Julia Unterscheider, Fergal D Malone -- Monitoring: Biochemical and Biophysical. Sonographic Dating and Standard Fetal Biometry / Eliza Berkley, Alfred Abuhamad -- Fetal Lung Maturity / Alessandro Ghidini, Sarah H Poggi -- Antepartum Fetal Monitoring / Brian L Shaffer, Julian T Parer -- Interpreting Intrapartum Fetal Heart Tracings / Michael Nageotte -- Maternal Disease. Sickle Cell Anemia / Scott Roberts -- Anemia / Alessandro Ghidini -- Thrombocytopenia / Robert M Silver -- Inherited and Acquired Thrombophilias / Michael J Paidas -- Thromboembolic Disorders / Christian M Pettker, Charles J Lockwood -- Cardiac Disease / Stephanie R Martin, Alexandria J Hill, Michael R Foley -- Renal Disease / David C Jones -- Pregnancy in Transplant Patients / James R Scott -- Gestational Diabetes Mellitus / Deborah L Conway -- Diabetes Mellitus / George Saade -- Hypothyroidism and Hyperthyroidism / Brian Casey -- Asthma / Michael Schatz -- Epilepsy / Autumn M Klein, Page B Pennell -- Chronic Hypertension / Heather A Bankowski, Dinesh M Shah -- Systemic Lupus Erythematosus / Christina S Han, Edmund F Funai -- Perinatal Infections / Jeanne S Sheffield -- Malaria / Richard M K Adanu -- Group B Streptococcal Infection / Ronald S Gibbs -- Hepatitis / Patrick Duff -- HIV Infection / Howard L Minkoff -- Pregnancy in Women with Physical Disabilities / Caroline C Signore -- Obstetric Complications. Recurrent Spontaneous Abortion / Charles J Lockwood -- Cervical Insufficiency / John Owen -- Gestational Hypertension, Preeclampsia, and Eclampsia / Labib M Ghulmiyyah, Baha M Sibai -- Postpartum Hemorrhage / Michael A Belfort -- Emergency Care / Garrett K Lam, Michael R Foley -- Rh and Other Blood Group Alloimmunizations / Kenneth J Moise -- Multiple Gestations / Karin E Fuchs, Mary E D'Alton -- Polyhydramnios and Oligohydramnios / Ron Beloosesky, Michael G Ross -- Prevention of Preterm Birth / Paul J Meis -- Pathogenesis and Prediction of Preterm Delivery / Catalin S Buhimschi, Charles J Lockwood -- Preterm Premature Rupture of Membranes / Brian M Mercer -- Management of Preterm Labor / Vincenzo Berghella -- Placenta Previa and Related Placental Disorders / Yinka Oyelese -- Complications of Labor and Delivery. Prolonged Pregnancy / Teresa Marino, Errol R Norwitz -- Induction of Labor / Nicole M Petrossi, Deborah A Wing -- Cesarean Delivery / Michael W Varner -- Vaginal Birth after Cesarean Delivery / Mark B Landon -- Breech Delivery / Edward R Yeomans, Larry C Gilstrap -- Operative Vaginal Delivery / Edward R Yeomans -- Obstetric Analgesia and Anesthesia / Gilbert J Grant -- Patient Safety / Christian M Pettker -- Neonatal Encephalopathy and Cerebral Palsy / Maged M Costantine, Mary E D'Alton, Gary D V Hankins -- Procedures. Genetic Amniocentesis and Chorionic Villus Sampling / Ronald J Wapner -- Fetal Surgery / Robert H Ball, Hanmin Lee -- Index.
  • Actin filament dynamics using microfluidics -- Bacterial actin-like proteins: purification and characterization of self-assembly properties -- Quantitative analysis of microtubule self-assembly kinetics and tip structure -- Biochemical reconstitution of the WAVE regulatory complex -- Rotational movement of formins evaluated by using single-molecule fluorescence polarization -- Single-molecule studies of actin assembly and disassembly factors -- Assaying microtubule nucleation of the [gamma]-Tubulin ring complex -- Reconstituting dynamic microtubule polymerization regulation by TOG domain proteins -- Generation of differentially modified microtubules using In Vitro enzymatic approaches -- Engineering defined motor ensembles with DNA origami -- Construction and analyses of elastically coupled multiple-motor systems -- Reconstitution of cortical dynein function -- Reconstitution of microtubule-dependent organnelle transport -- Reconstituting the motility of isolated intracellular cargoes -- Reconstitution of contractile actomyosin arrays -- Directed actin assembly and motility -- In Vitro reconstitution of dynamic microtubules interacting with actin filament networks -- Measuring kinetochore-microtubule interaction In Vitro -- Micropattern-guided assembly of overlapping pairs of dynamic microtubules -- WAVE regulatory complex activation -- Dissecting principles governing actin assembly using yeast extracts -- Xenopus egg ctyoplasm with intact actin -- Glycogen-supplemented mitotic cytosol for analyzing xenopus egg microtubule organization -- Spindle assembly on immmobilized chromatin micropatterns.
  • Introduction: challenges in reducing disparities in reproductive and perinatal outcomes through evidence-based public health -- Methodological approach to assessing the evidence -- Evidence-based public health: origins, assumptions, and cautions -- Access to family planning and induced abortion -- Preconceptional health promotion -- Infertility status and infertility treatment: racial and ethnic disparities -- Public health interventions for perinatal HIV and STI screening in pregnancy -- What is the role of prenatal care in reducing racial and ethnic disparities in pregnancy outcomes? -- Current approaches to reducing premature births and implications for disparity elimination -- Prenatal case management of pregnant women: what is the evidence for its contribution to a reduction of disparities in perinatal outcomes? -- Behavioral treatment methods for pregnant smokers: the evidence base for prenatal care programs and professional practice -- Substance abuse in pregnancy: the impact of screening and treatment on improving perinatal outcomes and reducing racial and ethnic disparities -- The evidence for perinatal depression screening and treatment -- Supplemental nutrition programs during pregnancy and the early postnatal period -- Group prenatal care and doula care for pregnant women -- Contemporary childbirth in the United States: interventions and disparities -- Regionalized perinatal care: an evidence-based intervention in development.
  • "In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. The volume on Arthritis covers, rheumatoid arthritis, cytokines, leukocyte immunoglobulin-like receptors, alleles, cardiovascular risk, disease outcomes, treatment protocols, and drugs for arthritis. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.
  • "In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. This volume on Asthma covers, inter alia, asthma care in primary care centers, rhinosinusitis and asthma, asthma and psychological distress, inhalation techniques for different inhalers, emergency treatment for acute asthma, therapy for elderly patients, treatment for pediatric asthma, nursing care at home and so on. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.
  • Epidemiology of angina / John F. Beltrame -- Chest pain : cardiac and non-cardiac causes / Geraldine Lee -- Coronary plaque rupture in patients with acute coronary syndrome / Toshio Imanishi -- The use and application of angina questionnaires / Norul Badriah Hassan and Muhammad Termizi Hassan -- American College of Cardiology/American Heart Association guidelines for ST-elevation myocardial infarction : overview of guidelines for care before, during, and after STEMI / Rohit S. Loomba and Rohit R. Arora -- Non-invasive coronary angiography with cardiac CT in patients with angina pectoris / Christof Burgstahler, Harald Brodoefel, and Stephen Schroeder -- Drugs used in angina : an overview / Mario Marzilli and Alda Huqi -- Current clinical application of direct thrombin inhibitors in angina pectoris / Bernardo Cortese and Marco Centola -- Anti-anginal drugs in focus : trimetazidine / Mario Marzilli and Alda Huqi -- Enhanced external counterpulsation therapy in coronary artery disease management / Ozlem Soran and Debra L. Braverman.
  • 1. Abdominal Pain -- 2. Abnormal Vaginal Bleeding -- 3. Amenorrhea -- 4. Anemia -- 5. Anxiety -- 6. Arthralgia -- 7. Back Pain -- 8. Behavior Problems in Children -- 9. Bleeding and Bruising -- 10. Blood in Stool -- 11. Breast Masses and Nipple Discharge -- 12. Chest Pain -- 13. Child Abuse -- 14. Confusion -- 15. Congestion -- 16. Cough -- 17. Depression -- 18. Diarrhea -- 19. Dizziness -- 20. Earache -- 21. Family Discord -- 22. Fatigue -- 23. Fever -- 24. Headache -- 25. Health Maintenance -- 26. Heartburn -- 27. Hypertension -- 28. Jaundice -- 29. Lower Extremity Pain and Swelling -- 30. Lymphadenopathy -- 31. Menopause --- 32. Neck Pain -- 33. Pelvic or Genital Pain -- 34. Polyuria -- 35. Rashes -- 36. Seizures -- 37. Sexual Dysfunction -- 38. Shortness of Breath -- 39. Sleep Disorders -- 40. Sore Throat -- 41. Substance Abuse -- 42. Urinary Problems -- 43. Vaginal Discharge -- 44. Generalized Weakness -- 45. Weight Change
  • Evidence-based information plays a critical role in clinical practice decisions. Secondary sources are often unreliable; it.s up to the student, then, to critically assess peer-reviewed research literature. Using a highly structured yet accessible method, this text teaches students to critically analyze research from primary sources. Step-by-step approach. learn to recognize a meaningful study, clues to potential study flaws, and ways to apply solid evidence in clinical practice. Simple 6-point framework. learn to evaluate studies in terms of the authors trademark mnemonic device, M.A.A.R.I.E. (Methods, Assignment, Assessment, Results, Interpretation and Extrapolation). Unique Learning Aids - question checklists, real-world scenarious, flaw-catching exercises and more help to make complex concepts easy to grasp.
  • The diagnostic process -- Screening & health maintenance -- Abdominal pain -- Acid-base abnormalities -- AIDS/HIV infection -- Anemia -- Back pain -- Chest pain -- Cough, fever, and respiratory infections -- Delirium and dementia -- Diabetes -- Diarrhea, Acute -- Dizziness -- Dyspnea -- Edema -- Fatigue -- Gastrointestinal bleeding -- Headache -- Hypercalcemia -- Hypertension -- Hyponatremia and hypernatremia -- Jaundice and abnormal liver enzymes -- Joint pain -- Rashes -- Renal failure, acute -- Syncope -- Weight loss, involuntary -- Wheezing and stridor.
  • ""This book makes a great leap in the conceptualization of transdisciplinary approaches, as well as provides concrete examples in practice, teaching, policy, and research."" -From the Foreword by Edward F. Lawlor, dean and the William E. Gordon Distinguished Professor, the Brown School; and founding director, Institute for Public Health at Washington University in St. Louis The complexity of public health and social problems is becoming more challenging. Understanding and designing solutions for these problems requires perspectives from multiple disciplines and fields as well
  • OBJECTIVES: There are two generally accepted strategies for managing atrial fibrillation (AF): rate control and rhythm control. However, within each strategic approach there are a large number of potential pharmacological and nonpharmacological therapies, and the comparative safety and effectiveness of these therapies--both within and between strategies--are uncertain. DATA SOURCES: We searched PubMed(r), Embase(r), and the Cochrane Database of Systematic Reviews for relevant English-language comparative studies. REVIEW METHODS: Two investigators screened each abstract and full-text article for inclusion, abstracted data, rated quality and applicability, and graded evidence. When possible, random-effects models were used to compute summary estimates of effects. RESULTS: Our review included 182 articles (148 unique studies): 14 studies relevant to rate-control drugs, 3 relevant to strict versus lenient rate control, 6 relevant to rate-control procedures versus drugs in patients for whom initial pharmacotherapy was ineffective, 42 relevant to antiarrhythmic drugs and electrical cardioversion for conversion to sinus rhythm, 83 relevant to rhythm-control procedures and drugs for maintenance of sinus rhythm, and 14 focusing on the comparison of rate- and rhythm-control strategies. Our ability to draw conclusions for the Key Questions addressing rate-control strategies was limited by the small number of available studies that assessed comparable therapies and outcomes, although we found a high strength of evidence for consistent benefit of calcium channel blockers (verapamil or diltiazem) compared with digoxin for ventricular rate control. For comparisons of methods for electrical cardioversion for conversion to sinus rhythm, there was high strength of evidence that use of a single biphasic waveform was more effective than use of a single monophasic waveform (odds ratio [OR] 4.39; 95% confidence interval [CI], 2.84 to 6.78) and that a 200 Joules (J) biphasic shock was less effective than a 360 J monophasic shock (OR 0.16; 95% CI, 0.05 to 0.53). Drug enhancement of external electrical cardioversion demonstrated a benefit compared with no drug enhancement (moderate strength of evidence), but data evaluating whether any one antiarrhythmic agent was more effective than others at restoring sinus rhythm were inconclusive. Our review found high strength of evidence supporting pulmonary vein isolation (PVI) versus antiarrhythmic drugs for maintenance of sinus rhythm in a select subset of patients (those with paroxysmal AF who were younger and with no more than mild structural heart disease; OR 6.51; 95% CI, 3.22 to 13.16) and moderate strength of evidence for adding a surgical Maze procedure at the time of other cardiac surgery (specifically mitral valve surgery) as opposed to mitral valve surgery alone (OR 5.80; 95% CI, 1.79 to 18.81). Comparing rate- and rhythm-control strategies, there was moderate strength of evidence supporting comparable efficacy with regard to all-cause mortality (OR 1.34; 95% CI, 0.89 to 2.02); cardiovascular mortality (OR 0.96; 95% CI, 0.77 to 1.20); stroke (OR 0.99; 95% CI, 0.76 to 1.30); and bleeding events (OR 1.10; 95% CI, 0.87 to 1.38). Cardiovascular hospitalizations were lower with rate-control strategies than with rhythm-control strategies (OR 0.25; 95% CI, 0.14 to 0.43; high strength of evidence). We were unable to conclude whether treatment effects varied by patient characteristics due to the paucity of studies that focused on specific patient subgroups. CONCLUSIONS: In assessing clinical outcomes associated with rate- versus rhythm-control strategies, our review of recent evidence agrees with prior reviews demonstrating little overall difference in outcomes between these two strategic approaches. Uncertainties still exist within specific subgroups of interest, among the wide variety of pharmacological and procedural therapies within each strategic approach, and in the impact of strategies on long-term clinical outcomes. Specifically, our review highlights the need for additional studies evaluating final outcomes such as mortality, stroke, and cardiovascular hospitalizations.
  • Taking the history -- Physical examination -- How to manage the patient after history and examination -- How to conduct urodynamic studies: essentials of a good urodynamic report -- Outcome measures used to assess response -- Conservative therapy of urodynamic stress incontinence -- Step-by-step guide to treatment of overactive bladder (OAB)/Detrusor overactivity -- Anal incontinence and disorders of obstructive defecation -- Surgery for urodynamic stress incontinence -- Management of prolapse -- Recurrent bacterial cystitis in women -- Interstitial cystitis.
  • "The Yale Swallow Protocol is an evidence-based protocol that is the only screening instrument that both identifies aspiration risk and, when passed, is able to recommend specific oral diets without the need for further instrumental dysphagia testing. Based upon research by Drs. Steven B. Leder and Debra M. Suiter, an easily administered, reliable, and validated swallow screening protocol was developed and can be used by speech-language pathologists, nurses, otolaryngologists, oncologists, neurologists, intensivists, and physicians assistants. In addition, the protocol can be used in a variety of environments, including acute care, rehabilitation, and nursing homes. The Yale Swallow Protocol meets all of the criteria necessary for a successful screening test, including being simple to administer, cross-disciplinary, cost effective, acceptable to patients, and able to identify the target attribute by giving a positive finding when aspiration risk is present and a negative finding when aspiration risk is absent. Additionally, early and accurate identification of aspiration risk can significantly reduce health-care costs associated with recognized prandial aspiration."--Publisher's website.

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