Books by Subject
Drug Therapy
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A to Z drug facts Ovid
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Adrenomedullin in cardiovascular disease 2005, Springer
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Advances in the design of antifungal clinical trials Lane Catalog record
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Adverse drug reactions 2010, SpringerPt. 1. Target organ toxicity. -- Drug-induced liver injury / Michael Holt, Cynthia Ju.-- Drug herpersensitivity reactions involving skin / Oliver Hausmann, Benno Schnyder, Werner J. Pichler.-- Adverse drug reactions affecting blood cells / Richard H. Aster.-- Molecular mechanisms of adverse drug reactions in cardiac tissue / Reza Tabrizchi.-- Mechanisms of drug-induced nephrotoxicity / Thomas D. Nolin, Jonathan Himmelfarb.-- Receptor- and reactive intermediate-mediated mechanisms of teratogenesis / Peter G. Wells, Crystal J.J. Lee, Gordon P. McCallum, Julia Perstin, Patricia A. Harper.-- Pt. II. Mediators/Biochemical pathways.-- Role of reactive metabolites in drug-induced hepatotoxicity / A.M. Srivastava, J. L. Maggs, D. J. Antoine, D. P. Williams, D. A. Smith, B. K. Park.-- Role of cytokines in the mechanism of adverse drug reactions / Mary Jane Masson, Lindsay A. Collins, Lance R. Poh.-- Keap1-Nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity / Ian M. Copple, Christopher E. Goldring, Neil R. Kitteringham, B. Kevin Park.-- Signal transduction pathways involved in drug-induced liver injury / Derick Han, Mie Shinohara, Maria D. Ybanez, Behnam Saberi, Neil Kaplowitz.-- Mictrochondrial involvement in drug-induced liver injury / Dominique Pessayre, Abdellah Mansouri, Alain Berson, Bernard Fromenty.-- Pt. III. Examples/Models.-- Mechanisms of acetaminophen-induced liver necrosis / Jack A. Hinson, Dean W. Roberts, Laura P. James.-- Drug-induced liver injury in humans: the case of Ximelagtran / M. Keisu, T.B. Andersson.-- Troglitazone / Tsuyoshi Yokoi.-- Neviropine hypersensitivity / M. Popovic, J.M. Shenton, J. Chen, A. Baban, T. Tharmanathan, B. Mannargudi, D. Abdulla, J.P. Uetrecht.-- Mechanisms of adverse drug reactions to biologics / Janet B. Clarke.-- Pt. IV. Risk factors/Screening drug candidates.-- Pharmacogenetics of idiosyncratic adverse drug reactions / Munir Pirmohamed.-- Danger hypothesis applied to idiosyncratic drug reactions / Jinze Li, Jack P. Uetrecht.-- Approaches for minimizing metabolic activation of new drug candidates in drug discovery / Sanjeev Kumar, Kaushik Mitra, Kelem Kassahun, Thomas A. Baillie.
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Aloes 2004, CRCnetBASEAloe vera in thermal and frostbite injuries / Michael K. Obeng J., Gary D. Motykie, Robert L. McCauley and P. Heggers -- Plant saccharides and the prevention of sun-induced skin cancer / Faith M. Strickland and Ronald P. Pelley -- Aloes and the immune system / Ian R. Tizard and Lalitha Ramamoorthy -- Bioactivity of A. arborescens preparations / Akira Yagi -- Aloe biology: the chromosomes of aloe : variation on a theme / Peter Brandham -- Aloe leaf anatomy / David F. Cutler -- Pests of aloes / Monique S.J. Simmonds.The Plants : aloes in habitat / Leonard E. Newton -- Taxonomy of Aloaceae / Gideon F. Smith and Elsie M.A. Steyn -- Aloe constituents : aloe chemistry / Tom Reynolds -- Aloe polysaccharides / Yawei Ni, Kenneth M.Yates and Ian R. Tizard -- Aloe lectins and their activities / Hiroshi Kuzuya, Kan Shimpo and Hidehiko Beppu -- Analytical methodology : the gel analysis of aloe pulp and its derivatives / Yawei Ni and Ian R. Tizard -- Analytical methodology : the exudate / Tom Reynolds -- Industrial processing and quality control of A. barbadensis / Ronald P. Pelley, Todd A. Waller and Faith M. Strickland -- Therapeutic activity of aloes: healing powers of aloes / Nicola Mascolo, Angelo A. Izzo, Francesca Borrelli, Giulia di Carlo, Lidia Sautebin and Francesco Capasso -- Aloe vera in wound healing / Gary D. Motykie and John P. Heggers.
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Analgesia 2007, SpringerPart I. Introduction --Peripheral and central mechanism of pain generation /H.G. Schaible --Part II.Drugs in clinical use --Opioids /C. Zöllner, C. Stein --Antipyretic analgesics: nonsteroidal antiinflammatory drugs, selective COX-2 inhibitors, paracetamol and pyrazolionones /B. Hinz, K. Brune --Local anesthetics /R. Yanagidate, G.R. Strichartz --Serotonin receptor ligands: treatments of acute migraine and cluster headache /P.J. Goadsby --Anti-convulsants and anti-depressants /A.H. Dickenson, J. Ghandehari --Part III.Compounds in preclinical development --Neuropeptide and kinin antagonists /R. G. Hill, K.R. Oliver --Glutamate receptor ligands /V. Neugebauer --Adrenergic and cholinergic compounds /R. D. Sanders, M. Maze --Cannabinoids and pain /I.J. Lever, A.S.C. Rice --Part IV.Future targets in analgesia research --Adenosine and ATP receptors /J. Sawynok --Ion channels in analgesia research /J.N. Wood --Protein kinases as potential targets for the treatment of pathological pain /R. R. Ji, Y. Kawasaki, Z. Y. Zhuang, Y.R. Wen, Y.Q. Zhang --Part V.Pain Management beyond pharmacotherapy --Placebo and endogenous mechanisms of analgesia /F. Bededetti --Limitations of pharmacotherapy: behavioral approaches to chronic pain /H. Flor, M. Diers --Subject index.
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Antibiotic policies 2007, Springer
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Antibiotics 2010, Springer
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Anticancer drug development 2002, ScienceDirectA brief history of cancer chemotherapy -- Novel targets in the cell cycle and cell cycle checkpoints -- Growth factor and signal transduction targets for cancer therapy -- Cell death pathways as targets for anticancer drugs -- Drug resistance pathways as targets -- Role of matrix metalloproteinases and plasminogen activators in cancer invasion and metastasis: therapeutic strategies -- Tumor vasculature as a target -- Gene-directed enzyme prodrug therapy -- Tumor antigens as targets for anticancer drug development -- Structure-based drug design and its contributions to cancer chemotherapy -- The contribution of synthetic organic chemistry to anticancer drug development -- Biosynthetic products for anticancer drug design and treatment: the bryostatins -- DNA-encoded peptide libraries and drug discovery -- Mechanism-based high-throughput screening for novel anticancer drug discovery -- Tumor cell cultures in drug development -- Screening using animal systems -- Relevance of preclinical pharmacology and toxicology to Phase I trial extrapolation techniques: relevance of animal toxicity -- Clinical trial design: incorporation of pharmacokinetic, pharmacodynamic, and pharmacogenetic principle -- Tumor imaging applications in the testing of new drugs -- Mechanistic approaches to Phase I clinical trials.
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Antifungal agents Springer ProtocolsSusceptibility testing methods of antifungal agents / Erika J. Ernst -- Deoxyribonucleic acid fingerprinting methods for Candida species / Shawn R. Lockhart ... [et al.] -- CARE-2 fingerprinting of Candida albicans isolates / Joachim Morschhäuser, Peter Staib, and Gerwald Köhler -- Targeted gene deletion in Candida albicans wild-type strains by MPAR flipping / Joachim Morschhäuser, Peter Staib, and Gerwald Köhler -- Application of Deoxyribonucleic acid microarray analysis to the study of azole antifungal resistance in Candida albicans / Katherine S. Barker and P. David Rogers -- Application of proteomic analysis to the study of azole antifungal resistance in Candida albicans / Massoumeh Z. Hooshdaran, George M. Hilliard, and P. David Rogers -- Techniques for antifungal susceptibility testing of Candida albicans biofilms / Gordon Ramage and Josʹe Luis Lʹopez-Ribot -- Natural products and antifungal drug discovery / Melissa R. Jacob and Larry A. Walker -- Use of an animal model of disseminated candidiasis in the evaluation of antifungal therapy / David Andes -- Murine model of invasive aspergillosis / Russell E. Lewis and Nathan P. Wiederhold -- Antifungal combinations / Roxana G. Vitale, Javier Afeltra, and Eric Dannaoui -- Post-antifungal effect methods / Roxana G. Vitale -- Evaluation of immunotherapy in invasive candidiasis: antifungal activity and cytokine expression assays / Maria Simitsopoulou and Emmanuel Roilides -- Interaction of histoplasma capsulatum with human macrophages, dendritic cells, and neutrophils / Simon L. Newman -- Immunology of infection caused by cryptococcus neoformans / Floyd L. Wormley, Jr. and John R. Perfect.
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Antiretroviral resistance in clinical practice NCBI Bookshelf
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Antisense therapeutics. 2nd ed. 2005, Springer ProtocolsAntisense therapeutics: a promise waiting to be fulfilled / M. Ian Phillips -- Antisense inhibition: oligonucleotides, ribozymes and siRNAs / Y. Clare Zhang ... [et al.] -- Local application of antisense for prevention of restenosis / Patrick L. Iversen ... [et al.] -- Antisense therapeutics for hypertension: targeting the renin-angiotensin system / M. Ian Phillips and Birgitta Kimura -- Antisense strategies for the treatment of heart failure / Sian E. Harding, Federica del Monte, and Roger J. Hajjar -- Clinical studies of antisense oligonucleotides for cancer therapy / Rosanne M. Orr and F. Andrew Dorr -- Antisense therapy in clinical oncology: preclinical and clinical experiences / Ingo Tamm -- Radionucleide-peptide nucleic acid diagnosis and treatment of pancreatic cancer / Eric Wickstrom ... [et al.] -- Suppression of pancreatic and colon cancer cells by antisense K-ras RNA expression vectors / Kazunori Aoki, Shumpei Ohnami, and Teruhiko Yoshida -- Induction of tumor cell apoptosis and chemosensitization by antisense strategies / Manuel Rieber and Mary Strasberg-Rieber -- Utility of an anti-oncogene ribozymes and antisense oligonucletoides in reversing drug resistance / Tadao Funato -- Transport of antisense across the blood-brain barrier / Laura B. Jaeger and William A. Banks -- Transdermal delivery of antisense oligonucletoides / Rhonda M. Brand and Patrick L. Iversen -- Antisense strategies for redirection of drug metabolism: using paclitaxel as a model / Vikram Arora -- Antisense oligonucletoide treatment of inflammatory bowel diseases / Bruce R. Yacyshyn -- Optimizing electroporation conditions for the intracellular delivery of morpholino antisense oligonucleotides directed against the hepatitis C virus internal ribosome entry site / Ronald Jubin.
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Antiviral nucleosides 2003, ScienceDirect
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Anxiety and anxiolytic drugs 2005, Springer
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Aromatase inhibitors 2006, Springer
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Bacterial resistance to antimicrobials 2002, CRCnetBASE
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Bacterial resistance to antimicrobials. 2nd ed. 2008, CRCnetBASEMicrobial drug resistance: a historical perspective / William C. Summers -- Ecology of antibiotic resistance genes / Abigail A. Salyers, Nadja Shoemaker, and David Schlesinger -- Global response systems that confer resistance / Paul F. Miller and Philip N. Rather -- Multidrug efflux pumps: structure, mechanism, and inhibition / Olga Lomovskaya ... [et al.] -- Mechanisms of aminoglycoside antibiotic resistance / Gerard D. Wright -- Resistance to [beta]-lactam antibiotics mediated by [beta]-lactamases : structure, mechanism, and evolution / Jooyoung Cha, Lakshmi P. Kotra, and Shahriar Mobashery -- Target modification as a mechanism of antimicrobial resistance / David C. Hooper -- Antibiotic permeability / Harry Taber -- Genetic methods for detecting bacterial resistance genes / Ad C. Fluit --Evolution and epidemiology of antibiotic-resistant pneumococci / Christopher Gerard Dowson and Krzysztof Trzcinski -- Antimicrobial resistance in the enterococcus / George M. Eliopoulos -- Methicillin resistance in staphylococcus aureus / Keeta S. Gilmore, Michael S. Gilmore, and Daniel F. Sahm -- Mechanism of drug resistance in mycobacterium tuberculosis / Alex S. Pym and Stewart T. Cole -- Antibiotic resistance in enterobacteria / Nafsika H. Georgopapadakou -- Resistance as a worldwide problem / Paul Shears -- Public health responses to antimicrobial resistance in outpatient and inpatient settings / Cindy R. Friedman and Arjun Srinivasan -- Antibacterial drug discovery in the 21st century / Steven J. Projan.
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Bioactive natural products. 2nd ed. 2008, CRCnetBASE
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Bioinformatics in cancer and cancer therapy 2009, SpringerThe emergence of bioinformatics : historical perspective, quick overview and future trends / Christos A. Ouzounis -- The statistical design and interpretation of microarray experiments / Kevin K. Dobbin and Richard M. Simon -- Whole-genome analysis of cancer / Steven A. Enkemann ... [et al.] -- Bioinformatics approaches to the analysis of the transcriptome of animal models of cancer / Mark J. Hoenerhoff ... [et al.] -- Significance of aberrant expression of miRNAs in cancer cells / George A. Calin ... [et al.] -- Proteomic methods in cancer research / Scot Weinberger and Egisto Boschetti -- Comprehensive genomic profiling for biomarker discovery for cancer detection, diagnostics and prognostics / Xiaofeng Zhou ... [et al.] -- Gene expression profiling of the leukemias : oncogenesis, drug responsiveness, and prediction of clinical outcome / Lars Bullinger, Hartmut Dohner, and Jonathon R. Pollack -- Personalized medicine in the clinical management of colorectal cancer / Anthony El-Khoueiry and Heinz Josef Lenz -- PIK3CA gene alterations in human cancers / Sérgia Velho, Carla Oliveira, and Raquel Seruca.
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Bisphosphonates and osteonecrosis of the jaw 2012, Springer
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Botulinum toxin in aesthetic medicine 2007, Springer
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Botulinum toxin in painful diseases 2003, Karger
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Camptothecins in cancer therapy 2005, SpringerMechanism of action of topoisomerase I poisons / Leroy F. Liu and Shyamal D. Desai -- Crystallographic insight into the mechanism of drug-induced topoisomerase I DNA damage / Alex B. Burgin, Jr., Bart L. Staker, and Lance Stewart -- Inhibitors of topoisomerase I function / Sidney M. Hecht -- Cytotoxic mechanisms of the topoisomerase I inhibitors / Yves Pommier ... [et al.] -- Biochemical and genetic analyses of DNA topoisomerase I-mediated DNA damage / Robert C.A.M. Van Waardenburg and Mary-Ann Bjornsti -- Preclinical models for evaluating topoisomerase-I targeted drugs / Aarti S. Juvekar ... [et al.] -- Mechanisms of resistance to camptothecins / Zeshaan A. Rasheed and Eric H. Rubin -- Recent advances in camptothecin drug design and delivery strategies / Thomas G. Burke ... [et al.] -- Clinical experience with 9-aminocamptothecin: lessons for new drug development / Chris H. Takimoto -- Clinical studies of rubitecan (9-nitro 20(s) camptothecin) / Hilary Hewes, Judith A. Smith, and Claire Verschraegen -- Irinotecan: current clinical status and pharmacological aspects / Laurent P. Rivory -- Clinical experience with topotecan / Aimee K. Bence and Val R. Adams -- The clinical development of lurtotecan: experience with water-soluble and liposomal forms / Keith T. Flaherty ... [et al.] -- Preclinical and clinical development of dx-8951f (exatecan mesylate): a hexacyclic camptothecin analog / Eric K. Rowinsky -- Camptothecins in the treatment of primary brain tumors / Clinton F. Stewart, Markos Leggas, and Henry S. Friedman -- Camptothecins in the treatment of lung cancer / Pankaj Kumar ... [et al.] -- Use of camptothecins in the treatment of leukemia and related disorders / Bejamin M.F. Mow and Scott H. Kaufmann.
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Cancer chemotherapy and biotherapy. 5th ed. 2011, OvidClinical strategies for cancer treatment: the role of drugs -- Target identification and drug discovery -- Clinical drug development and marketing approval -- Principles of pharmacokinetics -- Delivering anticancer drugs to brain tumors -- Pharmacogenetics -- Physical barriers to drug delivery -- Antifolates -- 5-fluoropyrimidines -- Cytidine analogues -- Purine antimetabolites -- Hydroxyurea -- Antimitotic drugs -- Alkylating agents -- Platinum analogues -- Bleomycin and other antitumor antibiotics -- Topoisomerase I-targeting drugs -- Topoisomerase II inhibitors: anthracyclines -- Topoisomerase II inhibitors: the epipodophyllotoxins -- Asparaginase -- Proteasome inhibitors -- Histone deacetylase inhibitors in oncology -- Differentiating agents -- Arsenic trioxide -- Antibodies -- Inhibitors of tumor angiogenesis -- Epidermal growth factor receptor inhibitors -- HER2 inhibitors -- Molecular targeted drugs -- Signaling inhibitors: IGFR, PI3K pathway, embryonic signaling inhibitors, and mitotic kinase inhibitors -- Cytokine therapy for cancer -- Cancer vaccines -- Adoptive cellular therapies -- Thalidomide and its analogs in the treatment of hematologic malignancies, including multiple myeloma, and solid tumors -- Hormonal therapy of breast cancer -- Hormone therapy for prostate cancer -- Drug therapy of pain in cancer patients -- Hematopoietic growth factors -- Antinausea medications -- Bisphosphonates and other bone-targeted therapies -- Intravenous access and catheter management -- Late effects of cancer chemotherapy -- Infertility after cancer chemotherapy.
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Cancer drug resistance 2006, Springer
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Cardiac drug therapy. 7th ed. 2007, Springer
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Cardiac safety of noncardiac drugs 2005, Springer
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Chemotherapy source book. 4th ed. 2008, OvidScientific basis of cancer chemotherapy -- Norton-simon hypothesis -- Drug resistance -- Principles of chemotherapy -- Clinical trials -- Hematopoietic growth factors -- Biologic response modifiers: principles of biotherapy -- Intraventricular and intrathecal therapy -- Intraperitoneal chemotherapy -- Continuous intravenous infusion chemotherapy -- Intraarterial chemotherapy -- Isolated regional therapy -- Hematopoietic stem cell transplantation -- Oral toxicity -- Dermatologic toxicity -- Extravasation -- Hypersensitivity reactions -- Ocular side effects of chemotherapy -- Cardiotoxicity of cancer therapy -- Pulmonary toxicity of antineoplastic therapy -- Gastrointestinal complications of chemotherapy -- Hepatotoxicity of chemotherapeutic agents -- Renal and electrolyte abnormalities due to chemotherapy -- Chemotherapy-induced peripheral neuropathy -- Vascular toxicity of antineoplastic agents -- Second malignancies after chemotherapy -- Chemotherapy in pregnancy -- Gonadal complications and teratogenicity of cancer therapy -- Central venous access for chemotherapy -- Systemic therapy for advanced melanoma -- General issues in brain tumor chemotherapy -- Chemotherapy of head and neck cancer -- Chemotherapy of lung cancer -- Breast cancer -- Gastrointestinal cancer -- Endocrine tumors -- Chemotherapy of genitourinary cancers -- Chemotherapy of gynecologic cancers -- Chemotherapy of carcinoma of unknown primary site -- Chemotherapy of bone and soft tissue sarcomas -- Chemotherapy for pediatric solid tumors -- Chemotherapy of hodgkin's lymphoma -- Non-hodgkin's lymphoma -- Acute myeloid leukemia, acute lymphoblastic leukemia, and chronic lymphocytic leukemia -- Chemotherapy of the myelodysplastic syndromes -- Management of myeloproliferative disorders and chronic myeloid leukemia -- Chemotherapy of multiple myeloma and other plasma cell disorders.
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Clinical drug trials and tribulations. 2nd ed., rev. and expanded. 2002, CRCnetBASE
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Clinical use of anti-infective agents 2012, Springer
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Clinician's guide to antiepileptic drug use 2006, OvidCarbamazepine -- Felbamate -- Gabapentin -- Lamotrigine -- Levetiracetam -- Oxcarbazepine -- Phenobarbital, primidone -- Phenytoin -- Pregabalin -- Tiagabine -- Topiramate -- Valproic -- Zonisamide.
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Colorectal cancer 2007, SpringerMolecular biology of colon cancer / William M. Grady -- Chemoprevention of colorectal cancer / Yu-Ning Wong ...[et al.] -- Colorectal cancer screening and surveillance / Arnold J. Markowitz -- Cytotoxic chemotherapy for metastatic colorectal cancer / M. Wasif Saif, Richard Kim, and Edward Chu -- Integration of antiangiogenic strategies in colorectal cancer treatment / John M. Strother and Charles D. Blanke -- The role of EGFR inhibition in colorectal cancer / Nabeel Shalan and Paulo M. Hoff -- Second-line strategies in the treatment of patients with metastatic colorectal cancer / Anthony B. El-Khoueiry and Heinz-Josef Lenz -- Adjuvant chemotherapy for colon cancer / Bert H. O'Neil ... [et al.] -- Management of locally advanced rectal cancer / Yu Jo Chua and David Cunningham -- Rationale for adjuvant and neoadjuvant chemotherapy in the resection of liver metastases / Axel Grothey and Steven A. Alberts -- Percutaneous radiofrequency ablation in the management of patients with colorectal cancer / Karen Brown -- Colorectal cancer imaging / Sean D. Curran and Laurence H. Schwartz -- Nursing issues in colorectal cancer chemotherapy / Ellen Hollywood and Deborah Semple -- Pain management in the colorectal cancer patient / Vivek Tim Malhotra -- Novel agents and new paradigms for colorectal cancer / Chris Takimoto and Russell Kruzelock.
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Combination cancer therapy 2005, SpringerTargeting of the EGFR as a modulator of cancer chemotherapy / Jose Baselga -- Cyclin dependent kinase inhibitors in combination chemotherapy / Manish A. Shah and Gary K. Schwartz -- Development of protein kinase C and cyclin-dependent kinase inhibitors as potentiators of cytotoxic drug action in leukemia / Steven Grant -- Carboxyamidotriazole, an inhibitor of nonvoltage operated calcium entry : single agent and combination therapy for ovarian carcinoma / Chad M. Michener and Elise C. Kohn -- Targeted alpha particle therapy : a rational approach to drug development in hematologic diseases and solid tumors / John M. Burke, David A. Scheinberg, and Joseph G. Jurcic -- Pharmacologic modulation of fluoropyrimidines : building upon the lessons of the past / Owen A. O'Connor -- Development of inhibitors of HER2 with taxanes : new directions in breast cancer therapy / Shanu Modi, Monica N. Fornier, and Andrew D. Seidman -- Targeting nf-b to increase the activity of cisplatin in solid tumors / Don S. Dizon ... [et al.] -- Combinations of chemotherapy and G3139, an antisense BCL-2 oligonucleotide / Luba Benimetskaya, Sridhar Nami, and C. A. Stein -- Use of animal models to evaluate signal transduction inhibitors as modulators of cytotoxic therapy / Beverly A. Teicher.
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Complement therapeutics 2013, Springer
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Comprehensive medicinal chemistry II ScienceDirectv. 1. Global perspective / volume editor, Peter D. Kennewell -- v. 2. Strategy and drug research / volume editor, Walter H. Moos -- v. 3. Drug discovery technologies / volume editor, Hugo Kubinyi -- v. 4. Computer-assisted drug design / volume editor, Jonathan S. Mason -- v. 5. ADME-Tox approaches / volume editors, Bernard Testa and Han van de Waterbeemd -- v. 6. Therapeutics areas I: central nervous system, pain, metabolic syndrome, urology, gastrointestinal and cardiovascular / volume editor, Michael Williams -- v. 7. Therapeutic areas II: cancer, infectious diseases, inflammation & immunology and dermatology / volume editors, Jacob J. Plattner & Manoj C. Desai -- v. 8. Case histories and cumulative subject index / volume editors, John B. Taylor & David J. Triggle.
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Daschner guide to in-hospital antibiotic therapy. 2nd ed. 2012, Springer
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Deoxynucleoside analogs in cancer therapy 2006, Springer
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Dermatological and transdermal formulations 2002, CRCnetBASE
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DNA repair in cancer therapy. 1st ed. 2012, ScienceDirectIntroduction and overview of current targets: bench to clinic / Mark R. Kelley -- 2. MGMT a critical DNA repair gene target for chemotherapy resistance / Stanton L. Gerson and Lili Liu -- 3. Blockade of base excision repair: inhibition of small lesions results in big consequences to cancer cells / Melissa Fishel and Carlo Vascotto -- 4. PARP inhibitors -- scientific rationale and clinical development for cancer / Ruth Plummer, Nicola J. Curtin and Yvette Drew -- 5. Inhibiting selective DNA polymerases for therapeutic intervention / Anthony J. Berdis -- 6. Targeting the nucleotide excision repair pathway for therapeutic applications / John Turchi and Stephan M. Patrick -- 7. Homologous recombination and ATM/ATR targets / Henning Willers, Lee Zou and Heike N. Pfaffle -- 8. DNA double strand break repair by nonhomologous end joining and its clinical relevance / Michael Weinfeld and Susan Lees-Miller -- 9. Defective MMR-c-Abl-p73-GADD45alpha expression in cancer chemoresistance / David Boothman and Long Shan Li -- 10. DNA repair signaling targets / Susan Ashwell -- 11. Redox regulation of DNA repair and therapeutic / Millie M. Georgiadis -- 12. Personalized cancer medicine: DNA repair alterations is a promising predictive marker in cancer / Srinivasan Madhusudan -- 13. The role of DNA damage and repair in neurotoxicity caused by cancer therapies / Michael R. Vasko -- 14. Future directions with DNA repair inhibitors / Mark R. Kelley.
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Drug interactions in infectious diseases. 3rd ed. 2011, SpringerIntroduction to Drug-Drug Interactions -- Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion -- Mechanisms of Drug Interactions II: Transport Proteins -- Drug-Food Interactions -- Interactions Between Herbs and Antiinfective Medications -- Drug-Cytokine Interactions -- Beta-Lactam Antibiotics -- Macrolides, Azalides, and Ketolides -- Quinolones -- Glycopeptides, Lipopeptides, and Lipoglycopeptides -- Miscellaneous Antibiotics -- Drugs for Tuberculosis -- Drug Interactions with Antiretrovirals for HIV Infection -- Non-HIV Antiviral Agents -- Antifungal Agents -- Antimalarial Agents -- Antiprotozoal and Anthelmintic Agents -- Drug Interaction Considerations Throughout Drug Development -- Probe Cocktail Studies -- Design and Data Analysis in Drug Interaction Studies.
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Drugs affecting growth of tumours 2006, Springer
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Drugs for relapse prevention of alcoholism 2005, Springer
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Drugs in ophthalmology 2006, Springer
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Drugs in pregnancy and lactation. 9th ed. 2011, Ovid
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Entry inhibitors in HIV therapy 2007, Springer
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Genomic experimental approaches in oncology -- Pharmacogenomics of toxicity and response of chemotherapy -- Pharmacogenomics in clinical drug development in oncology.
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Handbook of cancer chemotherapy. 7th ed. 2007, OvidBiologic and pharmacologic basis of cancer chemotherapy and biotherapy / Roland T. Skeel and Samir N. Khleif -- Systemic assessment of the patient with cancer and long-term consequences of treatment / Roland T. Skeel -- Selection of treatment for the patient with cancer / Roland T. Skeel -- Antineoplastic drugs and biologic response modifiers : classification, use, and toxicity of clinically useful agents / Roland T. Skeel -- High-dose chemotherapy and hematopoietic stem cell transplantation in hematologic malignancies / Roberto Rodriguez and Chatchada Karanes -- Carcinomas of the head and neck / Harlan A. Pinto -- Carcinoma of the lung / Sophie Sun and Joan H. Schiller -- Carcinomas of the gastrointestinal tract / Al B. Benson, III -- Carcinomas of the pancreas, liver, gallbladder, and bile ducts / Rekha T. Chaudhary -- Carcinoma of the breast / Iman Mohamed -- Gynecologic cancer / Stephen Andrews -- Urologic and male genital cancers / Joseph S. Chan, Scott B. Saxman, and Craig R. Nichols -- Kidney cancer / Walter D. Y. Quan, Jr. and Mikhail Vinogradov -- Thyroid and adrenal carcinomas / Haitham S. Abu-Lebdeh and Samir N. Khleif -- Melanomas and other skin malignancies / Karen S. Milligan and Walter D. Y. Quan, Jr. -- Primary and metastatic brain tumors / April F. Eichler and Tracy T. Batchelor -- Soft tissue sarcomas / Robert S. Benjamin --Bone sarcomas / Robert S. Benjamin -- Acute leukemias / Olga Frankfurt and Martin S. Tallman -- Chronic leukemias / Peter White and Paul R. Walker -- Myeloproliferative diseases and myelodysplastic syndromes / Peter White and Paul R. Walker -- Hodgkin's lymphoma / Richard S. Stein and David S. Morgan -- Non-Hodgkin's lymphoma / Richard S. Stein and John P. Greer -- Multiple myeloma, other plasma cell disorders , and primary amyloidosis / Rachid Baz and Mohamad A. Hussein -- Metastatic cancer of unknown origin / James M. Leonardo -- Human immunodeficiency virus / Mary E. Cianfrocca -- Side effects of cancer chemotherapy / Janelle M. Tipton -- Infections : etiology, treatment, and prevention / Joan M. Duggan -- Transfusion therapy, bleeding, and clotting / Mary R. Smith and NurJehan Quraishy -- Oncology emergencies and critical care issues, anaphylaxis, spinal cord compression, cerebral edema, superior vena cava syndrome, hypercalcemia, tumor lysis syndrome, and respiratory failure / Roland T. Skeel -- Malignant pleural, peritoneal, and pericardial effusions and meningeal infiltrates / Rekha T. Chaudhary -- Cancer pain / Michael J. Fisch and Charles S. Cleeland -- Emotional and psychiatric problems in patients with cancer / Kathleen S. N. Franco-Bronson and Kristi S. Williams.
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Acute resuscitation -- Anesthesia -- Cardiovascular therapies -- Pulmonary therapies -- Renal, electrolyte, and acid base disturbances -- Endocrine therapies -- Gastroenterology, liver, and nutrition therapies -- Hematologic therapies -- Neurologic and psychiatric therapeutics -- Infectious diseases -- Allergy -- Poisonings -- Drug monitoring.
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Hormone therapy in breast and prostate cancer 2009, Springer
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Immunopotentiators in modern vaccines 2006, ScienceDirectMicroparticles as vaccine delivery systems / Derek T. O'Hagan -- MF59: a safe and potent adjuvant for human use / Audino Podda, Giuseppe Del Giudice, and Derek T. O'Hagan -- Development and evaluation of AS04, a novel and improved adjuvant system containing MPL and aluminium salt / Nathalie Garçon, Marcelle van Mechelen, and Martine Wettendorff -- Virosomes for vaccine delivery / Ian C. Metcalfe and Reinhard Glück -- The ISCOMATRIX adjuvant / Debbie Drane and Martin J. Pearse -- Mineral adjuvants / Erik B. Lindblad --Mucosal adjuvants based on cholera toxin and E. coli heat-labile enterotoxin / Jan Holmgren ... [et al.] -- Transcutaneous immunization using the heat-labile enterotoxin of E. coli as an adjuvant / Richard T. Kenney and Gregory M. Glenn -- T cell adjuvants and novel strategies for their identification / Laurence Van Overvelt and Philippe Moingeon -- Vaccination to treat noninfectious diseases: surveying the opportunities / Stephen W. Martin and Martin F. Bachmann -- Clinical evaluation of adjuvants / Jakub K. Simon and Robert Edelman -- Regulatory considerations in the nonclinical safety assessment of adjuvanted preventive vaccines / Elizabeth M. Sutkowski and Marion F. Gruber.Unravelling "the immunologist's dirty little secret" / Virgil E.J.C. Schijns -- Dendritic cells as targets and tools in vaccines / Imerio Capone, Paola Rizza, and Filippo Belardelli -- Host-derived molecules as adjuvants / Tom Barr, Jennifer Carlring, and Andrew W. Heath -- Innate immune mechanisms and the identification of immune potentiators as vaccine adjuvants / Achal Pashine, Jeffrey B. Ulmer, and Nicholas M. Valiante -- CpG oligodeoxynucleotides as vaccine adjuvants / Michael J. McCluskie and Risini D. Weeratna -- Toll-like receptor 4 agonists as vaccine adjuvants / David H. Persing ... [et al.] -- Immunomodulatory adjuvants from Quillaja saponaria / Charlotte Read Kensil --
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Induction chemotherapy 2011, Springer
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Inflammation in the pathogenesis of chronic diseases 2007, Springer
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Influenza virus sialidase-- a drug discovery target 2012, Springer
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Juzen-taiho-to (si-quan-da-bu-tang) 2005, CRCnetBASE
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Medication treatments for nicotine dependence 2007, CRCnetBASE
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Metabolic issues of clinical nutrition 2004, Karger
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mTOR pathway and mTOR inhibitors in cancer therapy 2010, SpringermTORC1: a signalling integration node involved in cell growth -- The regulation of the IGF-1/mTOR pathway by the p53 tumor suppressor gene functions -- mTOR signaling in angiogenesis -- mTORC1 signaling and hypoxia -- mTOR signaling in glioblastoma: lessions learned from bench to bedside -- mTOR and cancer therapy: general principles -- mTOR and cancer therapy: clinical development and novel prospects -- Drug combinations as a therapeutic approach for mTORC1 inhibitors in human cancer -- Downstream targets of mTORC1 -- Downstream of mTOR: translational and control of cancer -- Genome-wide analysis of translational control -- Translational control of cancer: implications for targeted therapy -- Downstream from mTOR: therapeutic approaches to targeting the eIF4F translation initiation complex.
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Multimodal concepts for integration of cytotoxic drugs 2006, Springer
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New concepts of antiviral therapy 2006, Springer
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New drug development. 2nd ed. 2010, SpringerNew drug development -- The regulatory environment -- Drug discovery -- Nonclinical research -- Designing clinical trials -- Conducting clinical trials I: Experimental methodology -- Conducting clinical trials II: Operational execution -- Statistical analysis -- Statistical significance -- Clinical significance -- Sample size estimation -- General safety assessments -- Efficacy assessment -- Cardiac and cardiovascular safety assessments -- Manufacturing small molecule drugs and biologicals -- Postmarketing surveillance -- Main themes and concluding comments -- References -- Index.
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Nitric oxide (NO) and cancer 2010, SpringerNitric oxide and cancer: an overview -- A role for eNOS in oncogenic Ras-driven cancer -- Dual role of nitric oxide in cancer biology -- Nitric oxide expression in cancer -- S-nitrosylation: how cancer cells say NO to cell death -- Cytotoxic and protective activity of nitric oxide in cancers -- Cytotoxic/protective activity of nitric oxide in cancer -- Nitric oxide and life or death of human leukemia cells -- Inhibition of apoptosis by endogenous nitric oxide in chronic lymphocytic leukaemia -- Nitric oxide: a rate-limiting factor for metastases development -- Nitric oxide inhibits tumor cell metastasis via dysregulation of the NF-kB/Snail/RKIP loop -- Sensitizing effect of nitric oxide to cytotoxic stimuli -- Nitric oxide is a promising enhancer for cancer therapy -- Role of nitric oxide for modulation of cancer therapy resistance -- Breaking resistance: role of nitric oxide in the sensitization of cancer cells to chemo- and immunotherapy -- Prognostic significance of iNOS in human melanoma -- Prognostic significance of iNOS in hepatocellular carcinoma -- Prognostic significance of iNOS in esophageal cancer -- Prognostic significance of nitrative DNA damage in infection- and inflammation-related carcinogenesis -- Nitric oxide-releasing molecules for cancer therapy and chemoprevention -- Nitric oxide: monotherapy or sensitiser to conventional cancer treatments? -- Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies -- (S, R)-3-Pheynyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide (GIT-27NO): new dress for nitric oxide mission -- Nitric oxide donors are a new class of anti-cancer therapeutics for the reversal of resistance and inhibition of metastasis -- Role of inducible nitric oxide synthase (iNOS) in regulation of nitric oxide (NO) production and stabilization of nitric oxide of HIF-1a: potential role of Se-Methylselenocysteine(MSC), an antioxidant multi-targeted small molecule.
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Ophthalmologic drug guide. 2nd ed. 2011, SpringerAntibacterial agents -- Antifungal agents -- Antiviral agents -- Anti-parasitic agents -- Anti-glaucoma agents -- Neuro-ophthalmology -- Anti-inflammatory agents -- Mydriatics, cycloplegics, and reversal agents -- Lubricants and viscoelastics -- Miscellaneous -- Anti-angiogenesis agents -- Contact lens solutions.
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Oral delivery of macromolecular drugs 2009, Springer
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Pain 2003, CRCnetBASE
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PEGylated protein drugs 2009, Springer
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Peptide antibiotics 2002, CRCnetBASE
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Percutaneous penetration enhancers. 2nd ed. 2006, CRCnetBASE
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Pharmaceutical gene delivery systems 2003, CRCnetBASE
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Pharmaceutical perspectives of cancer therapeutics 2009., Springer
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Pharmacogenetics 2010, SpringerPrinciples of Cancer Treatment / William G. Newman and Fiona H. Blackhall -- Clinical Pharmacology and Anticancer Drugs / Cristina Rodríguez-Antona and Julia Kirchheiner -- Principles of Genetics and Pharmacogenetics / William G. Newman -- Pharmacogenetics in the Management of Breast Cancer / Sacha J. Howell -- Pharmacogenetics in Colorectal Cancer / Roberta Ferraldeschi -- Pharmacogenetics in Lung Cancer / Fiona Blackhall -- Pharmacogenetics and Cancer Treatment in Children / P. Kellie Turner and Gareth J. Veal -- Pharmacogenetics in Palliative Care / Andrew A. Somogyi -- Genetic Predictors of Normal Tissue Response to Radiotherapy / Catharine M.L. West, Gillian C. Barnett, Alison M. Dunning, Rebecca M. Elliott and Neil G. Burnet -- Cancer Pharmacogenetics in Industry / Mireille Cantarini -- Ethical Issues in Pharmacogenetics / Tara Clancy -- Economics of Cancer Pharmacogenetics / Katherine Payne -- Future Advances in Cancer Pharmacogenomics / William G. Newman.
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Pharmacotherapy in chronic obstructive pulmonary disease 2004, CRCnetBASEProviding evidence of therapeutic benefit in clinical drug development / Steven Kesten and Theodore J. Witek -- Use of expiratory airflows and lung volumes to assess outcomes in COPD / Gary T. Ferguson -- Exercise testing / Denis E. O'Donnell and Katherine A. Webb -- Sleep-related breathing disturbances in COPD / Walter T. McNicholas -- Airway and alveolar determinants of airflow limitation in COPD / Noe Zamel -- Gas exchange / Antoni Ferrer, Joan Albert Barberá, and Roberto Rodriguez-Roisin -- Genetics of COPD / Jian-Quing He, Ikuma Kasuga, and Peter D. Paré -- Dyspnea / Donald A. Mahler -- Exacerbations of COPD / Jadwiga A. Wedzicha -- Health status measurement in COPD / Paul W. Jones -- Health resource utilization / Mitchell Friedman -- Anticholinergics / Peter J. Barnes -- β-adrenergic receptor agonist bronchodilators in the treatment of COPD / Stephen I. Rennard -- Theophylline and phosphodiesterase inhibitors in COPD / Alicia R. ZuWallack and Richard L. ZuWallack -- Corticosteroids in COPD / Mario Cazzola, Maria Gabriella Matera, and Romain Pauwels -- Antioxidants and protease inhibitors / Mario Cazzola and Maria Gabriella Matera -- An integrated approach to the pharmacological therapy of COPD / Bartolome R. Celli.
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Pharmacotherapy of cachexia 2006, CRCnetBASE
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Pharmacotherapy of obesity 2004, CRCnetBASE
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Plants that fight cancer 2004, CRCnetBASE
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Pocket guide to critical care pharmacotherapy 2008, Springer
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Preventing medication errors and improving drug therapy outcomes 2003, CRCnetBASE
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Protein kinase C in cancer signaling and therapy 2010, SpringerProtein kinase C in cancer signaling and therapy: introduction and historical perspective -- Regulation of conventional and novel protein kinase C isozymes by phosphorylation and lipids -- Phorbol esters and diacylglycerol: the PKC activators -- Diacylglycerol signaling: the C1 domain, generation of DAG and termination of signals -- Regulation of PKC by protein-protein interaction in cancer -- Introduction: PKC isozymes in the control of cell function -- Regulation and function of protein kinase C signaling -- PKC and control of the cell cycle -- PKC and the control of apoptosis -- Atypical PKC's, NF-kB and inflammation -- Introduction: PKC and cancer -- Protein kinase C, p53, and DNA damage -- PKCs as mediators of the hedgehog and Wnt signaling pathways -- PKC-PKD interplay in cancer -- Transgenic mouse models to investigate functional specificity of protein kinase C isoforms in the development of squamous cell carcinoma, a nonmelanoma human skin cancer -- PKC isozymes and skin cancer -- PKC and breast cancer -- PKC and prostate cancer -- Protein kinase C and lung cancer -- Introduction [PKC isozymes as targets for cancer therapy] -- PKC and resistance to chemotherapeutic agents -- PKCd as a target for chemotherapeutic drugs -- Atypical PKCs as targets for cancer therapy.
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Protein tyrosine kinases 2006, SpringerProtein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro -- Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward -- Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.] -- Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin -- JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki -- Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville -- Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.] -- Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.] -- Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens -- Phosphoproteomics in drug discovery and development / Michel F. Moran.
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Sparking signals 2008, Springer
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Targeted delivery of small and macromolecular drugs 2010, CRCnetBASETherapeutic potential of targeted drug delivery / Ajit S. Narang and Ram I. Mahato -- Antibody therapies for liver malignancy and transplantation / John M. Luk and Kwong-Fai Wong -- Transferrin receptor-mediated transcytosis in intestinal epithelial cells for gastrointestinal absorption of protein drugs / Nurmamet Amet ... [et al.] -- Ionizing radiation for tumor targeted drug delivery / Roberto Diaz, Li Zhou, and Dennis E. Hallahan -- Recent advances in gene expression and delivery systems / Ravikiran Panakanti and Ram I. Mahato -- Cellular barriers for nucleic acid delivery and targeting / Arto Urtti -- Targeted delivery systems of non-viral nucleic acid-based therapeutics / Ga Yong Shim ... [et al.] -- Delivery and targeting of oligonucleotides and siRNA / Ningning Yang and Ram I. Mahato -- Liposomes for non-viral gene delivery / Jiasheng Tu ... [et al.] -- Delivering the bullet to the right intracellular target : a cellular perspective on drug delivery / Maria Teresa Tarragâo-Trani and Brian Storrie -- Mitochondria-targeted drug delivery / Volkmar Weissig and Gerard G. M. D'Souza -- Site-specific prodrug activation strategies for targeted drug action / Mark D. Erion -- Enzyme-activated prodrug strategies for targeted drug action / Jarkko Rautio ... [et al.] -- Targeting colon and kidney : pathophysiological determinants of design strategy / Ajit S. Narang and Ram I. Mahato -- Principles and practice of pulmonary drug delivery / Vivek Gupta, Chandan Thomas, and Fakhrul Ahsan -- Recent advances in ocular drug delivery : role of transporters, receptors, and nanocarriers / Gyan P. Mishra ... [et al.] -- Injectable polymers for regional drug delivery / Rajendra P. Pawar ... [et al.] -- Polymer-drug conjugates / Lucienne Juillerat-Jeanneret and Feride Cengelli -- Polymer micelles for drug delivery / Sungwon Kim and Kinam Park -- Multifunctional stimuli-responsive nanoparticles for targeted delivery of small and macromolecular therapeutics / Srinivas Ganta, Arun Iyer, and Mansoor Amiji -- Physiological stress responsive gene regulation systems for tissue targeting / Hyun Ah Kim and Minhyung Lee.
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Targeted therapies in cancer 2007, Springer
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Telomerase inhibition 2007, Springer ProtocolsMethods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.
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Transdermal drug delivery. 2nd ed., rev. and expanded. 2003, CRCnetBASE
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Treatments from toxins 2007, CRCnetBASE
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Twenty years of G-CSF 2012, Springer
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Vetiveria 2002, CRCnetBASE
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