search indicatorNeed Help?

Books by Subject

Cell Biology

Displaying all 424 matches
  • Acute neuronal injury 2010, Springer
  • Adhesion protein protocols. 2nd ed. 2007, Springer Protocols
  • Adhesion-GPCRs 2010, Springer
    The adhesion GPCRs : gene repertoire, phylogeny, and evolution / Helgi B. Schith, Karl J.V. Nordstrom, and Robert Fredriksson -- Cadherins : developmental roles and future challenges / Caroline J. Formstone -- Latrophilin signalling in tissue polarity and morphogenesis / Tobias Langenhan and Andreas P. Russ -- GPS proteolytic cleavage of adhesion-GPCRs / Hsi-Hsien Lin ... [et al.] -- The latrophilins : "split-personality" receptors / John-Paul Silva and Yuri A. Ushkaryov -- Studies on the very large G protein-coupled-receptor : from initial discovery to determining its role in sensorineural deafness in higher animals / D. Randy McMillan and Perrin C. White -- Adhesion-GPCRs in the CNS / Natalie Strokes and Xianhua Piao -- GPR56 interacts with extracellular matrix and regulates cancer progression / Lei Xu -- Adhesion-GPCRs in tumorigenesis / Gabriela Aust -- Immunity and adhesion-GPCRs / Simon Yona, Hsi-Hsien Lin, and Martin Stacey -- CD97 in leukocyte trafficking / Jorg Hamann ... [et al.] -- The role of CD97 in regulating adaptive T-cell responses / Ian Spendlove and Ruhcha Sutavani -- F4/80 : the macrophage specific adhesion-GPCR and its role in immunoregulation / Hsi-Hsien Lin ... [et al.] -- Signal transduction mediated through adhesion-GPCRs / Norikazu Mizuno and Hiroshi Itoh -- Emerging roles of brain specific angiogenesis inhibitor 1 / Daeho Park and Kodi S. Ravichandran -- Adhesion-GPCRs in the male reproductive tract / Ben Davies and Christiane Kirchhoff.
  • Adipose tissue biology 2012, Springer
    1. Adipocyte Precursors: Developmental Origins, Self-Renewal, and Plasticity / Christian Dani and Nathalie Billon -- 2. Adipocyte Differentiation / José María Moreno-Navarrete and José Manuel Fernández-Real -- 3. Brown Adipose Tissue / Martin Klingenspor and Tobias Fromme -- 4. White Adipose Tissue / Stephane Gesta and C. Ronald Kahn -- 5. Sex Differences in Body Fat Distribution / Alain Veilleux and André Tchernof -- 6. Macrophages and Inflammation / Elise Dalmas, Joan Tordjman, Michèle Guerre-Millo, and Karine Clément -- 7. Adipocyte Growth and Factors Influencing Adipocyte Life Cycle / Srujana Rayalam and Clifton A. Baile -- 8. The Evolution of Mammalian Adipose Tissue / Caroline M. Pond -- 9. Dietary Determinants of Fat Mass and Body Composition / María A. Zulet, María J. Moreno-Aliaga, and J. Alfredo Martínez -- 10. The Genetic Determinants of Common Obesity-Susceptibility / Ruth J.F. Loos -- 11. Early Origins of Obesity and Developmental Regulation of Adiposity / Shalini Ojha and Helen Budge.
  • Adipose-derived stem cells 2011, Springer Protocols
    Isolation and culture of rhesus adipose-derived stem cells -- Isolation of human adipose-derived stem cells from lipoaspirates -- Isolation of murine adipose-derived stem cells -- In vitro adult rat adipose tissue-derived stromal cell isolation and differentiation -- In vitro adult canine adipose tissue-derived stromal cell growth characteristics -- Adipogenic differentiation of adult equine mesenchymal stromal cells -- Isolation and culture of porcine adipose tissue-derived somatic stem cells -- Automated isolation and processing of adipose-derived stem and regenerative cells -- Methods for the purification and characterization of human adipose-derived stem cells -- Characterization of human adipose-derived stem cells using flow cytometry -- Evaluation of cellular and humoral immune responses to allogeneic adipose-derived stem/stromal cells -- Adipose-derived stromal cells: Cytokine expression and immune cell contaminants -- Gel-based and gel-free proteomic technologies -- Adipogenic differentiation of adipose-derived stem cells -- Three-dimensional culture systems to induce chondrogenesis of adipose-derived stem cells -- Neural differentiation of human adipose tissue-derived stem cells -- Osteogenic differentiation strategies for adipose-derived mesenchymal stem cells -- Generation of adipose stromal cell-derived hepatic cells -- Adipose stem cell differentiation into smooth muscle cells -- Endothelial and cardiac regeneration from adipose tissues -- Epithelial differentiation of human adipose-derived stem cells -- Screening for epigenetic target genes that enhance reprogramming using lentiviral-delivered shRNA -- Adipogenic differentiation of human adipose-derived stem cells on 3D silk scaffolds -- A first approach for the production of human adipose tissue-derived stromal cells for therapeutic use -- Viral transduction of adipose-derived stem cells -- Use of adipose-derived stem cells in high-throughput screening to identify modulators of lipogenesis -- Preservation protocols for human adipose tissue-derived adult stem cells -- Soft tissue reconstruction -- Methods for analyzing microRNA expression and function during osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells -- The generation and the manipulation of human multipotent adipose-derived stem cells -- Cell sheet technology for tissue engineering: The self-assembly approach using adipose-derived stromal cells -- Differentiation of adipose-derived stem cells for tendon repair -- Adipose-derived stem cells for skin regeneration -- Adipose-derived stem cells for periodontal tissue regeneration.
  • Adult stem cells 2006, ScienceDirect
    Ectoderm -- Mesoderm -- Endoderm -- Extraembryonic and perinatal stem cells.
  • Adult stem cells 2011, Springer
  • "A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last several decades, this book discusses the theoretical and experimental evidence and considerations the effects of strong electromagnetic fields and/or electric pulses and their importance in medicine and biology. The authors present the basic techniques applied in electroporation and the advanced methods for creation of nanopores, highlighting their basic science and clinical applications. Topics include nano electroporation, classic electroporation, experimental evidence for electroporation of living cells, and electroporation for cancer and wound healing"--Provided by publisher.
  • 1. Cancer Stem Cells: A Revisitation of the "Anaplasia" Concept / Roberto Scatena -- 2. Stem Cells and Cancer Stem Cells: New Insights / Toru Kondo -- 3. Molecular Biology of Cancer Stem Cells / Oswaldo Keith Okamoto -- 4. Biomarkers of Cancer Stem Cells / Jun Dou and Ning Gu -- 5. Cancer Stem Cells and the Microenvironment / Alfonso Colombatti, Carla Danussi, Eliana Pivetta, and Paola Spessotto -- 6. Leukemia Stem Cells / Steven W. Lane and David A. Williams -- 7. Cancer Stem Cells and the Central Nervous System / Serdar Korur, Maria Maddalena Lino, and Adrian Merlo -- 8. Cancer Stem Cells and Glioblastoma Multiforme: Pathophysiological and Clinical Aspects / Akio Soeda, Mark E. Shaffrey, and Deric M. Park -- 9. Breast Cancer Stem Cells / Nuria Rodríguez Salas, Enrique González González, and Carlos Gamallo Amat -- 10. Colon Cancer Stem Cells / Ugo Testa -- 11. Liver Tumor-Initiating Cells/Cancer Stem Cells: Past Studies, Current Status, and Future Perspectives / Kwan Ho Tang, Stephanie Ma, and Xin-Yuan Guan -- 12. Pancreatic Cancer Stem Cells / Erica N. Proctor and Diane M. Simeone -- 13. Cancer Stem Cells and Renal Carcinoma / Benedetta Bussolati and Giovanni Camussi -- 14. Cancer Stem Cells: Proteomic Approaches for New Potential Diagnostic and Prognostic Biomarkers / Patrizia Bottoni, Bruno Giardina, and Roberto Scatena -- 15. Cancer Stem Cells: An Innovative Therapeutic Approach / Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio, Salvatore Scarà, and Bruno Giardina -- 16. Cancer Stem Cell and ATP-Binding Cassette: Which Role in Chemoresistance? / Andrea Silvestrini, Elisabetta Meucci, Giuseppe Ettore Martorana, Bruno Giardina, and Alvaro Mordente -- 17. Stem Cells and Cancer Stem Cells: Biological and Clinical Interrelationships / Cinzia Bagalà and Carlo Barone -- 18. Immunomodulatory Functions of Cancer Stem Cells / Tobias Schatton, Jennifer Y. Lin, and Markus H. Frank.
  • Speakers at the symposium / Morita, M. -- Aging of the niche and the microenvironment and its role in stem cell aging / Geiger, H. -- Hematopoietic stem cell aging and cancer / Chen, Y., Ju, Z. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Kleinhans, K.N., Burkhalter, M.D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Morita, Y. -- Stem cell therapy and stress response in pancreas and intestine -- Sperka, T., Omrani, O. -- Niche-stem cell interations and environmental influences / Tang, D. -- Stem cells and metabolism / Missios, P., Guachalla, L. -- Molecular mechanisms of muscle stem cell aging / Baig, A.H., Tümpel, S. -- Neural stem cells in development and aging / Schmidt-Strassburger, U.
  • Advances in stem cell research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
  • Roles of the TNF family in tissue homeostasis and normal development -- Novel aspects of signaling activation by the TNF family: novel aspects of the functions of the TRAFs and cIAPs -- Novel aspects of signaling activation by the TNF: ubiquitin modification of signaling proteins -- Novel aspects of signaling activation by the TNF family: TNF signaling and gene regulatory networks -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: roles of the TNF family in infectious diseases -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: interrelationship of the TNF family and pattern recognition receptor signaling -- Novel aspects of immune regulation by the TNF family -- Control of lymphocyte function and repertoire by the TNF family -- Advances in applying our knowledge to therapy: mechanisms of pathological and therapeutic effects of the TNF family -- Advances in applying our knowledge to therapy: rational design of new means for therapeutic modulation of function of the TNF family -- Roles of the TNF family in neuronal development, function, and pathology -- Cell death mechanisms controlled by the TNF family -- Contributors to abstracts of talks and posters at the 12th TNF Conference -- Abstracts of talks and posters presented at the 12th TNF Conference.
  • Aging 2014, Karger
    The commitment of human cells to senescence / R. Holliday -- Evolutionary theories of aging can explain why we age / E. Le Bourg -- Control of cell replication during aging / A. Macieira-Coelho -- Cell senescence : role in aging and age-related diseases / J. Campisi, L. Robert, -- Aging of cell membranes : facts and theories / I. Zs.-Nagy -- Oxidative stress, mitochondrial dysfunction, and the mitochondria theory of aging / Y. Kong, S.E. Trabucco, H. Zhang -- Aging of connective tissues : experimental facts and theoretical considerations / J. Labat-Robert, L. Robert -- Aging of cell communication : loss of receptor function / L. Robert, T. Fulop -- On the immunological theory of aging / T. Fulop, J.M. Witkowski, G. Pawelec, C. Alan, A. Larbi -- Aging of the brain, dementias, role of infectious proteins : facts and theories / F. Morinet -- Aging as alteration / P.-A. Miquel -- Longevity and its regulation : centenarians and beyond / L. Robert, T. Fulop.
  • Aging research in yeast 2012, Springer
    Introduction -- Oxidative stresses and ageing -- The role of mitochondria in the aging processes of yeast -- The retrograde response and other pathways of interorganelle communication in yeast replicative aging -- Chronological aging in Saccharomyces cerevisiae -- Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- Maximising the yeast chronological lifespan -- Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae -- DNA damage and DNA replication stress in yeast models of aging -- Yeast aging and apoptosis -- Cellular homeostasis in fungi: impact on the aging process -- Genome-wide analysis of yeast aging -- Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities -- Evolution of asymmetric damage segregaton: a modelling approach -- Cellular ageing and the actin cyoskeleton.
  • This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.
  • Apoptosis 2009, Springer
  • Apoptosis 2010, CRCnetBASE
  • Apoptosis 2004, Springer
    1. Caspase Regulation at the Molecular Level / Hitto Kaufmann and Martin Fussenegger, p. 1-23 -- 2. The BCL-2 Family / Amelia Petch and Mohamed Al-Rubeai, p. 25-47 -- 3. The IGF-1 Receptor in Cell Survival: Signalling and Regulation / Patrick Kiely, Denise O'Gorman, Anthony Lyons and Rosemary O'Connor, p. 49-92 -- 4. Apoptosis in Hepatocytes / N. Mukwena and Mohamed Al-Rubeai, p. 93-106 -- 5. Programmed Cell Death in Plants During Development and Stress Responses / S. Panter and M. Dickman, p. 107-152 -- 6. A Systems View of Cell Death / Jeffrey Varner and Martin Fussenegger, p. 153-179 -- 7. The Role of Caspases in Apoptosis and Their Inhibition in Mammalian Cell Culture / T. Sauerwald and M. Betenbaugh, p. 181-210 -- 8. Improvement of Industrial Cell Culture Processes by Caspase-9 Dominant Negative and Other Apoptotic Inhibitors / Jana van De Goor, p. 211-221 -- 9. Therapeutic Small Molecule Inhibitors of BCL-2 / Pierre Beauparlant and Gordon Shore, p. 223-237 -- 10. Apoptosis Control Based on Down-Regulating the Inhibitor-of-Apoptosis (IAP) Proteins: Xiap Antisense and Other Approaches / E. Lacasse, p. 239-280 -- 11. Monitoring of Apoptosis / Adiba Ishaque and Mohamed Al-Rubeai, p. 281-306 -- 12. Molecular Imaging of Programmed Cell Death; from Basic Mechanisms to Clinical Applications / Bas Kietselaer, Chris Reutelingsperger and Leonard Hofstra, 307-27.
  • Apoptosome 2010, Springer
  • Arterial chemoreception 2012, Springer
  • Arterial chemoreceptors 2009, Springer
  • Asymmetric cell division 2007, Springer
  • Autophagy v. 1-, 2014, ScienceDirect
    v. 2, 2014 ScienceDirect
    v.3, 2014 ScienceDirect
    Volume 1. Molecular mechanisms -- Volume 2. Role in general diseases -- Volume 3. Mitophagy.
  • Autophagy and cancer 2013, Springer
    This book covers the latest advances in the field of autophagy and cancer from the basics of the molecular machinery for autophagy induction and regulation up to current areas of interest, including modulation of autophagy and drug discovery for cancer prevention and treatment. The reader will be initially introduced to the historical context of autophagy, followed by a summary of the key players in autophagy, a discussion on the origin of autophagosomes, and an overview of signal transduction regulation of autophagy. The next chapters deal with the complex relationship between autophagy and tumorigenesis through in-depth discussions of how autophagy influences cell survival, apoptosis, inflammation, immunity, tumor microenvironment, metabolic stress, DNA damage, and genomic instability. The remaining chapters discuss how autophagy affects cancer cell response to therapy and how to best modulate autophagy for therapeutic benefit - what to target and how to target. We hope that this monograph will be an invaluable reference source for professionals, students, postdoctoral fellows, and senior scientists working in the fields of autophagy and cancer.
  • Culture of primary adherent cells and a continuously growing nonadherent cell line / Cheryl D. Helgason -- Detection of mycoplasma contaminations / Cord C. Uphoff and Hans G. Drexler -- Eradication of mycoplasma contaminations / Cord C. Uphoff and Hans G. Drexler -- Authentication of scientific human cell lines: easy-to-use DNA fingerprinting / Wilhelm G. Dirks and Hans G. Drexler -- Cytogenetic analysis of cell lines / Roderick A.F. MacLeod and Hans G. Drexler -- Human and mouse hematopoietic colony-forming cell assays / Cindy L. Miller and Becky Lai -- Isolation and culture of murine macrophages / John Q. Davies and Siamon Gordon -- Isolation and culture of human macrophages / John Q. Davies and Siamon Gordon -- Development of T-lymphocytes in mouse fetal thymus organ culture / Tomoo Ueno ... [et al.] -- In vitro generation of lymphocytes from embryonic stem cells / Renée F. de Pooter, Sarah K. Cho and Juan Carlos Zúñiga-Pflücker --Hematopoietic development of human embryonic stem cells in culture / Xinghui Tian and Dan S. Kaufman -- Generation of murine stromal cell lines: models for the microenvironment of the embryonic mouse aorta-gonads-mesonephros region / Robert A.J. Oostendorp, Kirsty Harvey, and Elaine E. Dzierzak -- Culture of human and mouse mesenchymal cells / Emer Clarke -- Isolation, purification, and cultivation of murine and human keratinocytes / Frizell L. Vaughan and Ludmila I. Bernstam -- Isolation and culture of primary human hepatocytes / Edward L. LeCluyse ... [et al.] -- Primary kidney proximal tubule cells / Mary Taub -- Enzymatic dissociation and culture of normal human mammary tissue to detect progenitor activity / John Stingl, Joanne T. Emerman, and Connie J. Eaves -- Generation and differentiation of neurospheres from murine embryonic day 14 central nervous system tissue / Sharon A. Louis and Brent A. Reynolds -- Isolation and culture of skeletal muscle myofibers as a means to analyze satellite cells / Gabi Shefer and Zipora Yablonka-Reuveni -- Adult ventricular cardiomyocytes: isolation and culture / Klaus-Dieter Schlüter and Daniela Schreiber --Isolation and culture of primary endothelial cells / Bruno Larrivée and Aly Karsan -- Studying leukocyte rolling and adhesion in vitro under flow conditions / Susan L. Cuvelier and Kamala D. Patel -- Isolation and characterization of side population cells / Margaret A. Goodell, Shannon McKinney-Freeman, and Fernando D. Camargo -- Scalable production of embryonic stem cell-derived cells / Stephen M. Dang and Peter W. Zandstra.
  • BetaSys 2011, Springer
  • Glycomics: An Overview of the Complex Glycocode / Garima Gupta and Avadhesha Surolia -- Structural Glycomic Approaches to Molecular Recognition Events on Cell Surfaces / Koichi Kato -- ISCSM2011 Chondroitin Sulfate E-type Structure at Tumor Cell Surface Is Involved in Experimental Metastasis / Kazuyuki Sugahara and Shuji Mizumoto -- Chondroitin Sulfate-Specific Novel Hydrolase in Human / Shuhei Yamada -- Identification of Endothelial Cell Surface Carbohydrate-Binding Receptors by Carbohydrate Ligand Mimicry Peptides / Michiko N. Fukuda -- Lysosomal Enzyme Sorting Receptors - Where Did They First Appear in the Animal Kingdom? / Suryanarayanaraju Vegiraju, Suresh Koduru and Siva Kumar Nadimpalli -- Endoplasmic Reticulum-Targeted Bcl-2 Inhibitable Mitochondrial Fragmentation Initiates ER Stress-Induced Cell Death / B. C. Bhavya, Deepa Indira, Mahendra Seervi, Jeena Joseph and Praveen K. Sobhan, et al. -- Interactions Between Caveolin-1 and Sphingolipids, and Their Functional Relevance / Sandro Sonnino, Simona Prioni, Vanna Chigorno and Alessandro Prinetti -- Cell Membrane Repair Pathway Involves Sensing of Dynamics of Caveolae and Caspase-1 / Saumya S. Srivastava and M. V. Krishnasastry -- Angiogenic Response of Endothelial Cells to Fibronectin / V. B. S. Kumar, R. I. Viji, M. S. Kiran and Perumana R. Sudhakaran -- Lactosylceramide Synthase as a Therapeutic Target to Mitigate Multiple Human Diseases in Animal Models / Subroto Chatterjee and Nezar Alsaeedi --Advanced FRET Methodologies: Protein-Lipid Selectivity Detection and Quantification / Fábio Fernandes, Manuel Prieto and Luís M. S. Loura -- Mechanism of GPCR-Directed Autoantibodies in Diseases / Hamiyet Unal, Rajaganapathi Jagannathan and Sadashiva S. Karnik -- Role of Membrane Cholesterol in Leishmanial Infection / Amitabha Chattopadhyay and Md. Jafurulla -- How Intact Is the Basement Membrane? Role of MMPs / S. Asha Nair, Sankar Jagadeeshan, Ramachandran Indu, Perumana R. Sudhakaran and M. R. Pillai -- Apoptosis of Breast Cancer Cells: Modulation of Genes for Glycoconjugate Biosynthesis and Targeted Drug Delivery / Subhash Basu, Rui Ma, Joseph R. Moskal, Manju Basu and Sipra Banerjee -- Altered Expression of Sialidases in Human Cancer / Taeko Miyagi, K. Takahashi, S. Moriya, K. Hata and K. Yamamoto, et al. -- Poly-ADP-Ribosylation of Vascular Endothelial Growth Factor and Its Implications on Angiogenesis / S. Binu, S. J. Soumya, V. B. S. Kumar and Perumana R. Sudhakaran -- Sphingolipid-Binding Domain in the Serotonin1A Receptor / Amitabha Chattopadhyay, Yamuna Devi Paila, Sandeep Shrivastava, Shrish Tiwari and Pushpendra Singh, et al. -- Withanolide D, Carrying the Baton of Indian Rasayana Herb as a Lead Candidate of Antileukemic Agent in Modern Medicine / Susmita Mondal, Saptarshi Roy, Rita Maity, Asish Mallick and Rajender Sangwan, et al. -- Engineered Glucose to Generate a Spectroscopic Probe for Studying Carbohydrate Biology / Ashish Tripathi, Vibha Singh, K. G. Aishwarya, Gopala Krishna Aradhyam and Srinivas Hotha -- Changes in Sialic Acid Content of Jelly Coat in Pesticide-Exposed Frog Eggs and Their Influence on Fertilization / H. P. Gurushankara, S. V. Krishnamurthy and V. Vasudev.
  • Theory of organelle biogenesis : a historical perspective / Barbara M. Mullock and J. Paul Luzio -- Protein coats as mediators of intracellular sorting and organelle biogenesis / Chris Mullins -- The role of proteins and lipids in organelle biogenesis in the secretory pathway / Thomas F.J. Martin -- Endoplasmic reticulum biogenesis : proliferation and differentiation / Erik Snapp -- The golgi apparatus : structure, function and cellular dynamics / Nihal Altan-Bonnet and Jennifer Lippincott-Schwartz -- Lysosome biogenesis and dynamics / Diane McVey Ward, Shelly L. Shiflett and Jerry Kaplan -- Nucleogenesis / Sui Huang -- Mitochondrial biogenesis / Danielle Leuenberger, Sean P. Curran and Carla M. Koehler -- The biogenesis and cell biology of peroxisomes in human health and disease / Stanley R. Terlecky and Paul A. Walton.
  • Biological adhesives 2006, Springer
  • Biological aging 2007, Springer Protocols
  • Breast cytopathology 2007, Springer
  • Caenorhabditis elegans. 2nd ed. 2012, ScienceDirect
    An updated edition of the classic Methods in Cell Biology volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come.
  • Caenorhabditis elegans. 2nd ed. 2011, ScienceDirect
    Pt.I Genetics and functional genomics :Mapping mutations in C. elegans /Eric J. Lambie --Specialized chromosomes and their uses in caenorhabditis elegans /Martin R. Jones,Zoe Lohn,Ann M. Rose --Genome engineering by transgene-instructed gene conversion in C. elegans /Valérie J.P. Robert,Jean-Louis Bessereau --RNAi methods and screening : RNAi based high-throughput genetic interaction screening /Patricia G. Cipriani,Fabio Piano --Dissection of genetic pathways in C. elegans /Zheng Wang,David R. Sherwood --Pt.II Molecular biology and biochemistry :Transgenesis in C. elegans /Vida Praitis,Morris F. Maduro --RNA processing in C. elegans /J. Jason Morton,Thomas Blumenthal --Analysis of microRNA expression and function /Priscilla M. Van Wynsberghe,Shih-Peng Chan,Frank J. Slack,Amy E. Pasquinelli --In situ hybridization of embryos with antisense RNA probes /Gina Broitman-Maduro,Morris F. Maduro --Gene-centered regulatory network mapping /Albertha J.M. Walhout --Affinity purification of protein complexes in C. elegans /Esther Zanin,Julien Dumont,RetoGassmann,Iain Cheeseman,Paul Maddox,Shirin Bahmanyar,Ana Carvalho,Sherry Niessen,John R. Yates III,Karen Oegema,Arshad Desai --Pt.III Development :Cell indentification and cell lineage analysis /Claudiu A. Giurumescu,Andrew D. Chisholm --Thegenetics and cell biology of fertilization /Brian D. Geldziler,Mathew R. Marcello,Diane C. Shakes,Andrew Singson --Imaging embryonic morphogenesis in C. elegans /Jeff Hardin --Molecular and genetic approaches for the analysis of C. elegans neuronal development /Dong Yan,Yishi Jin --Methods for evaluating the caenorhabditis elegans dauer state : standard dauer-formation assay using synthetic daumones and proteomic analysis of O-GIcNAc modifications /Jeeyong Lee,Kwang-Youl Kim,Kyoe-Jin Joo,Keekyeong Kim,Pan-Young Jeong,Young-Ki Paik.
  • Calcium Handling in hiPSC-Derived Cardiomyocytes --Myocardial Infarction and Heart Failure --Embryonic Stem Cells/Pluripotent Stem Cells --Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cardiomyocytes as a Source for Cardiac Regeneration --Spontaneous Cardiac Differentiation --Mesoderm Enrichment by Wnt-Signaling Growth Factors --Endoderm-Like Cell (END)-2 Co-culture Method --Calcium Homeostasis in Cardiomyocytes --Sarcoplasmic Reticulum (SR) Governs Maturity of Cardiomyocytes --SR Junctional Proteins Play a Role in Calcium Flux Between Cytosol and SR --Spatial and Temporal Ca2+ Wavefront Dictated by T-Tubule Structure --IP3-Mediated Calcium Release Contributes to Whole-Cell Calcium Transients --Calcium Handling Properties of hES-Derived Cardiomyocytes --Calcium Handling Properties of hiPSC-Derived Cardiomyocytes --iPSC-Derived Cardiomyocyte as a Potential Platform for Disease Modeling of the Impaired Calcium Handling-Related Syndrome --Disease Modeling of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) --Mitochondrial Dysfunction-Related Cardiomyopathy-Impaired SR Ca2+ Reuptake --Measurement of Cytosolic [Ca2+] by Fluorescence Confocal Microscopy --Materials --Calibration of Fluo-3 --Isolation of hiPSC- and hESC-Derived Cardiomyocytes --Recording of Cytosolic [Ca2+] --RT-qPCR of Calcium Handling Proteins.
  • Chapter 1. A Practical Guide to the Preparation of Ca2+ Buffers / Donald M. Bers, Chris W. Patton, Richard Nuccitelli -- Chapter 2. Photorelease Techniques for Raising or Lowering Intracellular Ca2+ / Robert Zucker -- Chapter 3. Making and Using Calcium-Selective Mini- and Microelectrodes / L. Hove-Madsen, S. Baudet, D.M. Bers -- Chapter 4. Construction, Theory, and Practical Considerations for using Self-referencing of Ca2+-Selective Microelectrodes for Monitoring Extracellular Ca2+ Gradients / Mark A. Messerli, Peter J.S. Smith -- Chapter 5. Practical Aspects of Measuring Intracellular Calcium Signals with Fluorescent Indicators / Joseph P.Y. Kao, Gong Li, Darryl A. Auston -- Chapter 6. Genetically Encoded Probes for Measurement of Intracellular Calcium / Michael Whitaker -- Chapter 7. Patch Clamp Methods for Studying Calcium Channels / David L. Armstrong, Christian Erxleben, Jody A. White -- Chapter 8. Nuclear Patch-Clamp Recording from Inositol 1,4,5-Trisphosphate Receptors / Taufiq Rahman, Colin W. Taylor -- Chapter 9. Confocal and Multiphoton Imaging of Intracellular Ca2+ / Godfrey Smith, Martyn Reynolds, Francis Burton, Ole Johan Kemi -- Chapter 10. The Use of Aequorins to Record and Visualize Ca2+ Dynamics: From Subcellular Microdomains to Whole Organisms / Sarah E. Webb, Kelly L. Rogers, Eric Karplus, Andrew L. Miller.
  • Calcium signaling 2012, Springer
    "This volume ... [explores] topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to oocytes, zebrafish and plants. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative." --Excerpt from publisher's description.
  • Calcium signalling 2013, Springer
    Summary --Introduction --Direct evidence - the digital approach --Fluorescence-based visualisation --Aequorin-based measurements --Measurement of calcium transport across membranes --Molecular biology based approaches --Manipulation of calcium --Calcium-induced function --Calcium signalling in cardiac myocytes --Calcium signalling in red blood cells --Perspective --Calcium Signalling Methodology --Non-linear and ultra high-speed imaging for explorations of the murine and human heart --A system for optical high resolution screening of electrical excitable cells --Concepts for optical high content screens of excitable primary isolated cells --A primary culture system for sustained expression of a calcium sensor in preserved adult rat ventricular myocytes --Calcium imaging of individual erythrocytes: Problems and approaches --Calcium Signalling in Cardiac Myocytes --Reduced Cardiac L-Type Ca²+ Current in Cav€ ₂ -/- Embryos Impairs Cardiac Development and Contraction With Secondary Defects in Vascular Maturation --Overexpression of junctin causes adaptive changes in cardiac myocyte Ca²+ signaling --Remodelling of Ca²+ handling organelles in adult rat ventricular myocytes during longterm culture --Functional and morphological preservation of adult ventricular myocytes in culture by sub-micromolar cytochalasin D supplement --Calcium Signalling in Red Blood Cells --The non-selective voltage-activated cation channel in the human red blood cell membrane: reconciliation between two conflicting reports and further characterisation --Ion channels in the human red blood cell membrane: Their further investigation and physiological relevance --Prostaglandin E₂ activates channelmediated calcium entry in human erythrocytes: An indication for a blood clot formation supporting process --Functional NMDA receptors in rat erythrocytes --Stimulation of human red blood cells leads to Ca²+-mediated intercellular adhesion --Lysophospatidic acid induced red blood cell aggregation in vitro --Regulation of phosphatidylserine exposure in red blood cells --Cation Channels in Erythrocytes - Historical and Future Perspective.
  • Annexinopathies / M.J. Hayes ... [et al.] -- Calpains and human disease / I. Bertipaglia and E. Carafoli -- Gelsolin and diseases / L. Spinardi and W. Witke -- Guanylate cyclase-activating proteins and retina disease / W. Baehr and K. Palczewski -- Pathologies involving the S100 proteins and rage / C.W. Heizmann ... [et al.] -- The calcium-sensing receptor: Physiology, pathophysiology and CaR-based therapeutics / E.M. Brown -- Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease / J. Colomer and A.R. Means -- Calcium channelopathies: Voltage-gated calcium channels / P.J. Adams and T.P. Snutch -- TRP channels in disease / S.E. Jordt and B.E. Ehrlich -- Diseases associated with altered ryanodine receptor activity / W.J. Durham ... [et al.] -- Inositol 1,4,5-tripshosphate receptor, calcium signalling and Huntington's disease / I. Bezprozvanny -- SERCA pumps and human diseases / A. Hovnanian -- The plasma membrane calcium ATPase and disease / B.L. Tempel and D.J. Shilling -- Diseases involving the Golgi calcium pump / J. Vanoevelen ... [et al.] -- Calcium signalling and cancer cell growth / T. Capiod ... [et al.] -- Calcium misregulation and the pathogenesis of muscular dystrophy / F.W. Hopf ... [et al.] -- Calcium and cell death / A. Verkhratsky -- Calcium and cell death: The mitochondrial connection / P. Bernardi and A. Rasola -- Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models / K.N. Green ... [et al.] -- Calcium and cardiomyopathies / E.G. Kranias and D.M. Bers -- Calcium signalling and calcium transport in bone disease / H.C. Blair ... [et al.].
  • Cancer stem cells 2007, Springer
  • Cancer stem cells : historical perspectives and lessons from leukemia / Christopher R. Cogle -- Cancer stem cells in breast cancer / Jenny E. Chu and Alison L. Allan -- Cancer stem cells in brain cancer / Xin Wang, Chitra Venugopal, and Sheila K. Singh -- Cancer stem cells in colorectal cancer / Mauro Biffoni, Eros Fabrizi, and Lucia Ricci-Vitiani -- Cancer stem cells in pancreatic cancer / Jorge Dorado, Alicia G. Serrano, and Christopher Heeschen -- Cancer stem cells in prostate cancer / Paula Kroon ... [et al.] -- Cancer stem cells in melanoma / Ping Jin ... [et al.] -- Cancer stem cells in lung cancer / Jun Shen and Feng Jiang -- Cancer stem cells in ovarian cancer / Fang Fang ... [et al.] -- Cancer stem cells in hepatocellular cancer / Russell C. Langan and Itzhak Avital -- Cancer stem cells in head and neck cancer / Mark E.P. Prince and Samantha J. Davis -- Relationship between regulatory pathways in pluripotent stem cells and human tumors / Olga Gaidarenko and Yang Xu -- Influence of the embryonic microenvironment on tumor progression / Daniela Quail ... [et al.] -- The epithelial-to-mesenchymal transition and cancer stem cells / Jonas Fuxe -- Application of stem cell assays for the characterization of cancer stem cells / Pamela M. Willan and Gillian Farnie -- Zebrafish as a model to study stem cells in development, disease, and cancer / Viviana Anelli, Cristina Santoriello, and Marina C. Mione -- Imaging cancer stem cells / Paula Foster -- Mouse models for studying normal and cancer stem cells / David A. Hess -- Cancer stem cells and disease prognosis / Zeshaan A. Rasheed, Jeanne Kowalski, and William H. Matsui -- Mechanisms of radioresistance in cancer stem cells / Cleo Y-F Lee and Maximilian Diehn -- The role of ABC transporters in cancer stem cell drug resistance / Vera S. Donnenberg, Ludovic Zimmerlin, and Albert D. Donnenberg -- Resistance to endocrine therapy in breast cancer : are breast cancer stem cells implicated? / Ciara S. O'Brien ... [et al.] -- Future directions : cancer stem cells as therapeutic targets / Alysha K. Croker and Alison L. Allan -- Final thoughts : complexity and controversy surrounding the "cancer stem cell" paradigm / Craig Gedye, Richard P. Hill, and Laurie Ailles.
  • Caveolins and caveolae 2012, Springer
    Lipid rafts, caveolae, and GPI linked proteins / Valerie L. Reeves, Candice M. Thomas, and Eric J. Smart -- Caveolae and the regulation of endocytosis / Anna L. Kiss -- Caveolin : role in cell signaling / Cecile Boscher and Ivan Robert Nabi -- Regulation of ENOS in caveolae / Chieko Mineo and Philip W. Shaul -- Recent developments in the interactions between caveolin and pathogens / Fabiana S. Machado ... [et al.] -- Caveolin and breast cancer : a new clinical perspective / Isabelle Mercier and Michael P. Lisanti -- Caveolin and prostate cancer progression / Michael R. Freeman, Wei Yang, and Dolores Di Vizio -- Caveolins and caveolae, roles in insulin signalling, and diabetes / Peter Strolfors -- Atherosclerosis, caveolae, and caveolin / Stephanos Pavlides ... [et al.] -- Caveolins and heart diseases / Mathivadhani Panneerselvam, Hemal H. Patel, and David M. Roth -- Caveolins and lung function / Nikolaos A. Maniatis ... [et al.].
  • Early embryonic cell fate decisions in the mouse / Yojiro Yamanaka and Amy Ralston -- Nuclear architecture in stem cells / Kelly J. Morris, Mita Chotalia, and Ana Pombo -- Epigenetic regulation of pluripotency / Eleni M. Tomazou and Alexander Meissner -- Autosomal lyonization of replication domains during early mammalian development / Ichiro Hiratani and David M. Gilbert -- Preservation of genomic integrity in mouse embryonic stem cells / Peter J. Stambrook and Elisia D. Tichy -- Transcriptional regulation in embryonic stem cells / Jian Chien, Dominic Heng, and Huck Hui Ng -- Alternative splicing in stem cell self renewal and differentiation / David A. Nelles and Gene W. Yeo -- MicroRNA regulation of embryonic stem cell self renewal and differentiation / Collin Melton and Robert Blelloch -- Telomeres and telomerase in adult stem cells and pluripotent embryonic stem cells / Rosa M. Marión and Maria A. Blasco -- X chromosome inactivation and embryonic stem cells / Tahsin Stefan Barakat and Joost Gribnau -- Adult stem cells and their niches / Francesca Ferraro, Cristina Lo Celso, and David Scadden -- Adult stem cell differentiation and trafficking and their implications in disease / Ying Zhuge, Zhao-Jun Liu, and Omaida C. Velazquez -- Vertebrates that regenerate as models for guiding stem cells / Christopher L. Antos and Elly M. Tanaka -- Reprogramming of somatic cells to pluripotency / Masato Nakagawa and Shinya Yamanaka.
  • Cell biology of the axon 2009, Springer
  • ch. 1. Cells and Tissues, p. 1-18 -- ch. 2. From Water to DNA: The Chemistry of Life, p. 19-49 -- ch. 3. Membranes and Organelles, p. 51-63 -- ch. 4. DNA Structure and the Genetic Code, p. 65-85 -- ch. 5. DNA as a Data Storage Medium, p. 87-103 -- ch. 6. Transcription and the Control of Gene Expression, p. 105-127 -- ch. 7. Recombinant DNA and Genetic Engineering, p. 129-161 -- ch. 8. Manufacturing Protein, p. 163-181 -- ch. 9. Protein Structure, p. 183-211 -- ch. 10. Intracellular Protein Trafficking, p. 213-235 -- ch. 11. How Proteins Work, p. 237-256 -- ch. 12. Energy Trading within the Cell, p. 257-280 -- ch. 13. Metabolism, p. 281-308 -- ch. 14. Ions and Voltages, p. 309-324 -- ch. 15. The Action Potential, p. 325-340 -- ch. 16. Intracellular Signaling, p. 341-362 -- ch. 17. Intercellular Communication, p. 363-379 -- ch. 18. Mechanical Molecules, p. 381-400 -- ch. 19. Cell Cycle and Control of Cell Number, p. 401-422 -- ch. 20. Case Study: Cystic Fibrosis, p. 423-435 -- Appendix: Channels and Carriers, p. 437-440.
  • Cell cycle checkpoint control protocols 2004, Springer Protocols
  • Cell cycle control 2004, Springer Protocols
    Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle: an overview / John H. Doonan -- The C. elegans cell cycle: overview of molecules and mechanisms / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle: an overview / Anna Philpott and P. Renee Yew -- The mammalian cell cycle: an overview / Jane V. Harper and Gavin Brooks -- Synchronization of cell populations in G₁/S and G₂/M phases of the cell cycle / Jane V. Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams --Polo-like kinase-1: activity measurement and RNAi-mediated knockdown / Marcel A.T.M. van Vugt and René H. Medema -- The Ipl1/aurora kinase family: methods of inhibition and functional analysis in mammalian cells / Claire Ditchfield, Nicholas Keen, and Stephen S. Taylor -- Purification of the Ndc80 kinetochore subcomplex from xenopus eggs / Mark L. McCleland and P. Todd Stukenberg.The cell cycle and virus infection / Steven R. Emmett ... [et al.] -- Methods for preparation of proteins and protein complexes that regulate the eukaryotic cell cycle for structural studies / Julie Welburn and Jane Endicott -- E2F transcription factors and pRb pocket proteins in cell cycle progression / Ludger Hauck and Rüdiger von Harsdorf -- Forkhead (FOX) transcription factors and the cell cycle: measurement of DNA binding by foxO and foxM transcription factors / Katrina A. Bicknell -- Measurement of geminin activity in xenopus egg extracts / Thomas J. McGarry -- CDK-activating kinases: detection and activity measurements / Stéphane Larochelle and Robert P. Fisher -- Cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors: detection methods and activity measurements / Gavin Brooks -- Measurement of wee kinase activity / Paul R. Mueller and Walter F. Leise -- CDC25 dual-specificity protein phosphatases: detection and activity measurements / Sorab N. Dalal and Melanie Volkening -- Assaying cell cycle checkpoints: activity of the kinase chk1 / Carmela Palermo and Nancy C. Walworth --
  • The biology of cyclins and cyclin-dependent protein kinases: an introduction / Lucio Miele -- In situ immunofluorescence analysis: immunofluorescence microscopy / Amjad Javed ... [et al.] -- In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling / Amjad Javed ... [et al.] -- Immunofluorescence analysis using epitope-tagged proteins: in vitro system / Amjad Javed ... [et al.] -- Analysis of in vivo gene expression using epitope-tagged proteins / Amjad Javed ... [et al.] -- Chromatin immunoprecipitation / Amjad Javed ... [et al.] --Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay / Amjad Javed ... [et al.] -- Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion / Amjad Javed ... [et al.] -- Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction / Amjad Javed ... [et al.] -- Assays for cyclin-dependent kinase inhibitors / Adrian M. Senderowicz -- Protein degradation via the proteosome / Henry Hoff, Hong Zhang, and Christian Sell --The transformed phenotype / Henry Hoff ... [et al.] -- A morphologic approach to detect apoptosis based on electron microscopy / Martyn K. White and Caterina Cinti -- Detection of apoptotic deoxyribonucleic acid break by in situ nick translation / Carmela Trimarchi ... [et al.] -- Induction of deoxyribonucleic acid damage by alkylating agents / Salvatore Cortellino ... [et al.] -- Induction of deoxyribonucleic acid damage by γ irradiation / Salvatore Cortellino, David P. Turner and Alfonso Bellacosa -- Ultraviolet irradiation of cells / David P. Turner, Anthony T. Yeung, and Alfonso Bellacosa -- Transient production of retroviral- and lentiviral-based vectors for the transduction of mammalian cells / Tiziana Tonini ... [et al.] --Determination of functional viral titer by drug-resistance colony assay, expression of green fluorescent protein, and β-galactoside staining / Tiziana Tonini ... [et al.] -- Retroviral and lentiviral vector titration by the analysis of the activity of viral reverse transcriptase / Tiziana Tonini ... [et al.] -- Single and double colloidal gold labeling in postembedding immunoelectron microscopy / Nicoletta Zini ... [et al.] -- Multifluorescence labeling and colocalization analyses / Massimo Riccio ... [et al.].
  • Cell cycle regulation 2006, Springer
  • Brief description of the histological, cytological and functional aspects of the ovary / María Luisa Escobar, Gerardo H. Vázquez-Nin, and Olga M. Echeverría -- Embryonic development of the ovary, sexual reproduction and meiosis / Gerardo H. Vázquez-Nin, María Luisa Escobar, and Olga M. Echeverría -- Development of the ovary in the embryo, infancy, childhood, pre-puberty and puberty / Gerardo H. Vázquez-Nin ... [et al.] -- Apoptosis / María Luisa Escobar, Gerardo H. Vázquez-Nin, and Olga M. Echeverría -- Autophagy / María Luisa Escobar, Gerardo H. Vázquez-Nin, and Olga M. Echeverría -- Oncosis / María Luisa Escobar, Gerardo H. Vázquez-Nin, and Olga M. Echeverría -- Necrosis / Gerardo H. Vázquez-Nin, María Luisa Escobar, and Olga M. Echeverría -- Programmed cell death in fetal oocytes / Francesca Gioia Klinger and Massimo De Felici -- DNA damage and apoptosis in fetal and ovarian reserve oocytes / Massimo De Felici and Francesca Gioia Klinger -- Prefollicular cells / María Luisa Escobar, Gerardo H. Vázquez-Nin, and Olga M. Echeverría -- Prepubertal oocytes / Gerardo H. Vázquez-Nin, María Luisa Escobar, and Olga M. Echeverría -- Follicular cells / María Luisa Escobar, Gerardo H. Vázquez-Nin, and Olga M. Echeverría -- Follicular atresia in adult animals / Gerardo H. Vázquez-Nin, María Luisa Escobar, and Olga M. Echeverría -- Luteolysis / Gerardo H. Vázquez-Nin, María Luisa Escobar, and Olga M. Echeverría.
  • Defects in cell death pathways promote tumor development and progression, with potentially devastating consequences for cancer patients. Greater understanding of the defects occurring in cancer cells, and the unique characteristics of tumors which can make them vulnerable to cell death stimuli, offers tremendous opportunities for developing novel and effective anti-cancer therapies. In Cell Death in Cancer Biology and Treatment leading experts in the field provide a wealth of up-to-date knowledge regarding the molecular mechanisms and cell biological processes that control cell death. Each chapter also highlights recent advances in the translation of basic research findings into clinical trials. Beginning and established investigators alike will benefit from the thorough presentations of the most promising avenues for future development of cell death-based, anti-cancer strategies and agents. The volume begins with a detailed description of many of the cell death defects that have been identified in human tumor specimens. The unique bioenergetics of cancer cells, and the influence of the tumor microenvironment, autophagy, and cellular microRNAs on cancer cell death are then discussed, along with current progress in targeting these distinctive features and processes. Additional chapters describe recent advances, and the therapeutic benefits of targeting DNA repair pathways, protein chaperones, sphingolipid signaling, Bcl-2 family members, IAPs, death receptor signaling, the proteasome, and survival signaling emanating from the PI3K/AKT and RAS/RAF/MEK/ERK pathways. Finally, recent discoveries are presented regarding interactions between the immune system and dying cancer cells and the potential for optimizing these interactions to maximize anti-cancer activities. In summary, Cell Death in Cancer Biology and Treatment will be a valuable resource for scientists interested in cutting-edge understanding of aberrant cell death in cancer cells, and the multitude of innovative molecular targeting approaches that are actively being pursued to achieve selective activation of cell death in human malignancies.
  • 1.Introduction /Thomas Dittmar and Kurt S. Zänker --2.Heterochronic control of AFF-1-mediated cell-to-cell fusion in C. elegans /Lilach Friedlander-Shani and Benjamin Podbilewicz --3.Role of SNAREs in membrane fusion /Bhanu P. Jena --4.Molecular and cellular mechanisms of mammalian cell fusion /Xiaofeng Zhou and Jeffrey L. Platt --5.Membrane fusions during mammalian fertilization /Bart M. Gadella and Janice P. Evans --6.Trophoblast fusion /Berthold Huppertz and Martin Gauster --7.Macrophage fusion and multinucleated giant cells of inflammation /Amy K. McNally and James M. Anderson --8.Molecular mechanisms of myoblast fusion across species /Adriana Simionescu and Grace K. Pavlath --9.Cell-fusion-mediated reprogramming : pluripotency or transdifferentiation? : implications for regenerative medicine /Daniela Sanges, Frederic Lluis, and Maria Pia Cosma --10.Cell fusion and tissue regeneration /Manuel Álvarez-Dolado and Magdalena Martínez-Losa --11.Dendritic cell-tumour cell fusion vaccines /Walter T. Lee.
  • Introduction / Thomas Dittmar and Kurt S. Zänker -- Horizontal Gene Transfers with or without Cell Fusions in All Categories of the Living Matter / Joseph G. Sinkovics -- Class III Viral Membrane Fusion Proteins / Marija Backovic and Theodore S. Jardetzky -- Human Trophoblast in Trisomy 21: A Model for Cell - Cell Fusion Dynamic Investigation / André Malassiné, Guillaume Pidoux, Pascale Gerbaud, Jean Louis Frendo and Danièle Evain-Brion -- Cell Fusion and Hyperactive Osteoclastogenesis in Multiple Myeloma / Franco Silvestris, Sabino Ciavarella, Sabino Strippoli and Franco Dammacco -- Cell Fusion Hypothesis of the Cancer Stem Cell / Xin Lu and Yibin Kang -- Expression of Macrophage Antigens by Tumor Cells / Ivan Shabo and Joar Svanvik -- Leukocyte-Cancer Cell Fusion: Initiator of the Warburg Effect in Malignancy? / Rossitza Lazova, Ashok Chakraborty and John M. Pawelek -- Cell Fusion, Drug Resistance and Recurrence CSCs / Christa Nagler, Kurt S. Zänker and Thomas Dittmar -- The Role of Microvesicles in Malignancies / Erna Pap.
  • Cell fusions 2011, Springer
  • Cell imaging techniques 2005, Springer Protocols
    Molecular beacons: fluorescent probes for detection of endogenous mRNAs in living cells -- Second-harmonic imaging of collagen -- Visualizing calcium signaling in cells by digitized wide-field and confocal fluorescent microscopy -- Multifluorescence labeling techniques and confocal laser scanning microscopy on lung tissue -- Evaluation of confocal microscopy system performance -- Quantitative analysis of atherosclerotic lesion composition in mice -- Applications of microscopy to genetic therapy of cystic fibrosis and other human diseases -- Laser scanning cytometry: principles and applications -- Near-clinical applications of laser scanning cytometry -- Laser capture microdissection -- Analysis of asbestos-induced gene expression changes in bronchiolar epithelial cells using laser capture microdissection and quantitative reverse transriptase-polymerase chain reaction -- New approaches to fluorescence in situ hybridization -- Microarray image scanning -- Near-field scanning optical microscopy in cell biology and cytogenetics -- Porosome: the fusion pore revealed by multiple imaging modalities -- Secretory vesicle swelling by atomic force microscopy -- Imaging and probing cell mechanical properties with the atomic force microscopy -- Reflection contrast microscopy: the bridge between light and electron microscopy -- Three-dimensional analysis of single particles by electron microscopy: sample preparation and data acquisition -- Three-dimensional reconstruction of single particles in electron microscopy: image processing -- A new microbiopsy system enables rapid preparation of tissue for high-pressure freezing.
  • Cell migration Springer Protocols
  • The migrating cell / Entschladen, F., Zänker, K.S. -- Stem cell migration in health and disease / Dittmar, T. ... [et al.] -- Leukocyte motility and human disease / Cooper, K., Nuzzi, P., Huttenlocher, A. -- Coordination of leukocyte polarity and migration / Martín-Cófreces, N.B., Serrador, J.M., Sánchez-Madrid, F. -- Positioning phosphoinositide 3-kinase in chemokine and antigen-dependent T-lymphocyte navigation mechanisms / Ward, S.G. -- Migration of functionally specialized T-helper cells : TFH cells, Th17 cells, and FoxP3+ T cells / Kim, C.H. -- ADAMs and ectodomain proteolytic shedding in leukocyte and tumour cell migration / Ager, A., Knäuper, V., Poghosyan, Z. -- Guided tour of cell migration : signals and pathways / Ratke, J., Lang, K. -- Regulation of the E-cadherin adhesion complex in tumor cell migration and invasion / Menke, A., Giehl, K. -- The cytoskeletal connection : understanding adaptor proteins / Ziegler, W.H. -- Locomotor force generation by myosins / Jbireal, J.M.A., Entschladen, F., Zänker, K.S.
  • Cancer Morbidity and mortality result from invasive and metastatic spread. Advances in the field have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book presents an overview of these studies.
  • Sect. I. Biophysical chemistry, metabolism, second messengers, and ultrastructure. Biophysical chemistry of physiological solutions / Jeffrey c. Freedman -- Physiological structure and function of proteins / Matthew R. Pincus -- Cell membranes / Jeffrey C. Freedman -- Ionophores in planar lipid bilayers / Jeffrey C. Freedman -- Cell structure / Michael S. Forbes -- Signal transduction and second messengers / Aldebaran M. Hofer -- Calcium as an intracellular second messenger: mediation by calcium-binding proteins / John R. Dedman and Marcia A. Kaetzel -- Sect. II. Membrane potential, transport physiology, pumps, and exchangers. Diffusion and permeability / Nicholas Sperelakis and Jeffrey C. Freedman -- Origin of resting membrane potentials / Nicholas Sperelakis -- Gibbs-Donnan equilibrium potentials / Nicholas Sperelakis -- Mechanisms of carrier-mediated transport: facilitated diffusion, cotransport and countertransport / Steven M. Grassl -- Active ion transport by ATP-driven ion pumps / Robert A. Farley -- Ca2+ -ATPases / Tracy J. Pritchard, Istvan Edes and Evangelia G. Kranias -- Na+ -Ca2+ exchange currents / John H.B. Bridge, Natalia S. Torres and Michela Ottolia --Intracellular chloride regulation / Francisco J. Alvarez-Leefmans -- Osmosis and regulation of cell volume / Clive M. Baumgarten and Joseph J. Feher -- Intracellular pH regulation / Robert W. Putnam -- Sect. III. Membrane excitability and ion channels. Cable properties and propagation of action potentials / Nicholas sperelakis -- Electrogenesis of membrane excitability / Nicholas Sperelakis -- Patch-clamp techniques / Laura Conforti -- Structure and mechanism of voltage-gated ion channels / Simon Rock Levinson and William A. Sather -- Biology of gap junctions / Richard D. Veenstra -- Regulation of cardiac ion channels by cyclic nucleotide-dependent phosphorylation / Gordon M. Wahler and Nicholas Sperelakis -- Direct regulation of ion channels by GTP-binding proteins / Atsushi Inanobe and Yoshihisa Kurachi -- Developmental changes in ion channels / Takeshi Kobayashi ... [et al.] --Regulation of ion channel localization and activity through interactions with the cytoskeleton / Stephen Lambert -- Why are so many ion channels mechanosensitives? / Catherine E. Morris -- Sect. IV. Ion channels as targets for toxins, drugs, and genetic diseases. Ion channels as targets for toxins / Kenneth M. Blumenthal -- Ion channels as targets for drugs / Seth Robey, Kevin J. Sampson and Robert S. Kass -- Inherited diseases of ion transport / Robert A. Farley -- Sect. V. Synaptic transmission and sensory transduction. Ligand-gated ion channels / Kenneth R. Tovar and Gary L. Westbrook -- Synaptic transmission / Janusz B. Suszkiw -- Excitation-secretion coupling / Nicole Gallo-Payet and Marcel Daniel Payet -- Stimulus-response coupling in metabolic sensor cells / Stan Misler -- Cyclic nucleotide-gated ion channels / Anita L. Zimmerman -- Sensory receptors and mechanotransduction / Andrew S. French and Päivi H. Torkkeli -- Acoustic transduction / Daniel C. Marcus -- Visual transduction / Anita L. Zimmerman -- Gustatory and olfactory sensory transduction / Stephen D. Roper -- Infrared sensory organs / Stephen D. Roper and Michael S. Grace --Electroreceptors and magnetoreceptors / Timothy C. Tricas and Bruce A. Carlson -- Sect. VI. Muscle and other contractile systems. Skeletal muscle excitability / Nicholas Sperelakis, Judith Heiny and Hugo gonzalez-Serratos -- Cardiac action potentials / Gordon M. Wahler -- Smooth muscle excitability / Neil D. Detweiler ... [et al.] -- Excitation-contraction coupling in skeletal muscle / Judith A. Heiny and Gerhard Meissner -- Contraction of muscles: mechanochemistry / Richard J. Paul -- Flagella, cilia, actin- and centrin-based movement / Kenneth W. Foster -- Electrocytes of electric fish / Anthony L. Gotter, Marcia A. Kaetzel and John R. Dedman -- Sect. VII. Protozoa and bacteria. Physiological adaptations of protists / Michael Levandowsky -- Physiology of prokaryotic cells / Dennis W. Grogan -- Sect. VIII. Specialized processes: photosynthesis and bioluminescence. Photosynthesis / Darrell Fleischman -- bioluminescence / J. Woodland Hastings.
  • Heme oxygenase-1 and carbon monoxide in vascular regulation / Stefan W. Ryter and Augustine M.K. Choi -- Tumor necrosis factor-[alpha]/receptor signaling through the Akt kinase / Osman Nidai Ozes ... [et al.] -- Protein modifications by nitric oxide and reactive nitrogen species / Harry Ischiropoulos -- Redox signaling in hypoxic pulmonary vasoconstriction / E. Kenneth Weir ... [et al.] -- cGMP-dependent protein kinase in regulation of the perinatal pulmonary circulation / Usha Raj ... [et al.] -- Glutamate receptor activation in the pathogenesis of acute leg injury / Sami I. Said -- Carboxyl methylation of small GTPases and endothelial cell function / Sharon Rounds, Elizabeth O. Harrington, and Qing Lu -- Pressure-induced inflammatory signaling in lung endothelial cells / Wolfgang M. Kuebler -- Regulation of endothelial barrier function: contributions of the transcellular and paracellular pathways / Dolly Mehta, Richard D. Minshall, and Asrar B. Malik -- Sphingolipid signaling: implications for vascular biology / Margaret M. Harnett -- Regulations of cytokine signaling / Bao Q. Vuong ... [et al.] -- Cell signaling by vasoactive agents / Barry L. Fanburg ... [et al.] -- Reactive oxygen species and cell signaling in lung ischemia / Aron B. Fisher --Pulmonary vascular barrier regulation by thrombin and Edg receptors / Jeffrey R. Jacobson and Joe G.N. Garcia -- Second-messenger signaling in lung capillaries / Kaushik Parthasarathi -- Plasma membrane-to-nucleus calcium signaling / Giles E. Hardingham -- Signaling by mitochondria / Navdeep S. Chandel -- Pro-inflammatory signaling by endothelial focal complexes in lung / Sunita Bhattacharya -- Hydrogen peroxide as intracellular messenger: production, target, and elimination / Sue Goo Rhee ... [et al.] -- Calcium-inhibited adenylyl cyclase (AC6) controls endothelial cell barrier function / Troy Stevens.
  • Cell signaling reactions 2011, Springer
  • Cell therapy 2009, Springer
    Part 1. Regulatory. -- Regulation of Cell Product Manufacturing and Delivery: A United States Perspective / R.W. Lindblad -- The Regulatory Situation for Academic Cell Therapy Facilities in Europe / I. Slaper-Cortenbach, M. Scott, D. Herrmann, M. Introna and K. Theunissen, et al. -- A Regulatory System for Cell and Tissue Therapies: Proposed Approach in Australia / A. Farrugia -- Part 2. GMP Facility Design. -- University of Minnesota - Molecular and Cellular Therapeutics (MCT) / D.H. McKenna -- University of Pittsburgh Cancer Institute - Hematopoietic Stem Cell Laboratory (HSC Lab)/Immunological Monitoring and Cellular Products Laboratory (IMCPL) / D.L. Griffin, A.D. Donnenberg and T.L. Whiteside / Baylor College of Medicine - Center for Cell and Gene Therapy (CAGT) / A. Gee -- Design of a New GMP Facility - Lessons Learned / A. Gee -- Part 3. Professional Cell Therapy Standards. -- AABB Cell Therapy Standards / Z.M. Szczepiorkowski and E. Nunes -- Professional Standards for Cellular Therapies: Foundation for the Accreditation of Cellular Therapy (FACT) / P.I. Warkentin -- Part 4. Facility Operations -- Standard Operating Procedures / C.G. Lindgren -- Staffing, Training, and Competency / D.M. Kadidlo -- Cleaning Procedures / A. Gee and D.L. Lyon -- Environmental Monitoring / A. Gee and D.L. Lyon -- Supply Management / A. Gee and C.M. Rooney -- Facility Equipment / D.L. Griffin -- Quality / J.W. Atkins -- Product Manufacturing / A. Gee -- Product Review, Release, and Administration / N.H. Collins -- Use of a Facility Master File to Facilitate Regulatory Submissions for Cell Therapy Products / E.J. Read and H.M. Khuu.
  • Current views of the embryonic and neural stem cell : cell replacement or molecular repair? / Roya Sabetrasekh ... [et al.] -- Developing novel cell sources for transplantation in Parkinson's disease / Nicolaj S. Christophersen ... [et al.] -- Neural transplantation in the nonhuman primate model of Parkinson's disease / Kimberly B. Bjugstad and John R. Sladek, Jr. -- Cell-based therapy for Huntington's disease / Claire M. Kelly, Stephen B. Dunnett, and Anne E. Rosser -- Use of bone marrow stem cells as therapy for behavioral deficits in rodent models of Huntington's disease / Gary L. Dunbar, Justin D. Oh-Lee, and Laurent Lescaudron -- Human neuroteratocarcinoma cells as a neural progenitor graft source for cell transplantation in stroke / Cesario V. Borlongan ... [et al.] --Therapeutic applications of bone marrow-derived stem cells in neurologic injury and disease / C. Dirk Keene ... [et al.] -- Cell therapy for models of pain and traumatic brain injury / Mary Eaton and Jacqueline Sagen -- The use of sertoli cells in neural transplantation / Dwaine F. Emerich, Cesario V. Borlongan, and Craig Halberstadt -- The choroids plexus : a novel graft source for neural transplantation / Cesario V. Borlongan ... [et al.] -- Progress and challenges in immunoisolation for CNS cell therapy / Christopher G. Thanos and Dwaine F. Emerich -- Evidence-based methodology for advancing neural reconstruction / Stephen Polgar -- Hematopoietic cell therapy for brain repair / Martina Vendrame and Alison E. Willing -- Stem cells and regenerative medicine : commercial and pharmaceutical implications / L. Eduardo Cruz and Silvia P. Azevedo.
  • Stroke remains one of the main causes of death and disability worldwide. Effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.
  • Age-related macular degeneration: clinical findings, histopathology, and imaging techniques / Zarbin, M.A.; Casaroli-Marano, R.P.; Rosenfeld, P.J. -- General pathophysiology in retinal degeneration / Wert, K.J.; Lin, J.H.; Tsang, S.H. -- Juvenile-onset macular degeneration and allied disorders / North, V.; Gelman, R.; Tsang, S.H. -- Diagnosis and complementary examinations / Menghini, M.; Duncan, J.L. -- Stem cells for retinal repair / Stern, J.; Temple, S. -- Differentiation of pluripotent stem cells into retinal pigmented epithelium / Croze, R.H.; Clegg, D.O. -- Neural retinal regeneration with pluripotent stem cells / Ramsden, C.M.; Powner, M.B.; Carr, A.-J.F.; Smart, M.J.K.; da Cruz, L.; Coffey, P.J. -- Stem cells, retinal ganglion cells and glaucoma / Sluch, V.M.; Zack, D.J. -- Stem cells : immunology and immunomodulation / Tena, A.; Sachs, D.H. -- Biochemical restoration of aged human Bruch's membrane : experimental studies to improve retinal pigment epithelium transplant survival and differentiation / Sugino, I.K.; Sun, Q.; Cheewatrakoolpong, N.; Malcuit, C.; Zarbin, M.A. -- Approaches to cell delivery : substrates and scaffolds for cell therapy / Kundu, J.; Michaelson, A.; Baranov, P.; Young, M.J.; Carrier, R.L. -- Microdevice-based cell therapy for age-related macular degeneration / Lu, B.; Tai, Y.-C.; Humayun, M.S. -- Cell and gene therapy / Rao, R.C.; Zacks, D.N. -- Cellular manufacturing for clinical applications / Sheu, J.; Klassen, H.; Bauer, G. -- Regulatory issues in cell-based therapy for clinical purposes / Casaroli-Marano, R.P.; Tabera, J.; Vilarrodona, A.; Trias, E.
  • Cell-cell channels 2006., Springer
    Cell-cell channels and their implications for cell theory / Frantisek Baluska, Dieter Volkmann, and Peter W. Barlow -- Mating cell-cell channels in conjugating bacteria / Elisabeth Grohmann -- The tetrahymena conjugation junction / Eric S. Cole -- Cytoplasmic bridges in volvox and its relatives / Harold J. Hoops, Ichiro Nishii, and David L. Kirk -- Vegetative hyphal fusion in filamentous fungi / Nick D. Read and M. Gabriela Roca -- Plasmodesmata: cell-cell channels in plants / Yoselin Benitez Alfonso, Laurence Cantrill, and David Jackson -- Sieve-pore plugging mechanisms / Aart J.E. van Bel -- Actin and myosin VIII in plant cell-cell channels / Jozef Samaj ... [et al.] -- Cell-cell communication in wood / John R. Barnett -- TMV movement protein targets cell-cell channels in plants and prokaryotes: possible roles of tubulin- and FtsZ-based cytoskeletons / Manfred Heinlein -- Viral movement proteins induce tubule formation in plant and insect cells / Jan W.M. van Lent and Corinne Schmitt-Keichinger --Cell-cell movements of transcription factors in plants / Alexis Maizel -- Gap junctions: cell-cell channels in animals / Fabio Mammano -- Tunneling nanotubes: membranous channels between animal cells / Hans-Hermann Gerdes and Amin Rustom -- Cytoplasmic bridges as cell-cell channels of germ cells / Sami Ventelä -- Fusome as a cell-cell communication channel of drosophila ovarian cyst / Jean-René Huynh -- Cytonemes as cell-cell channels in human blood cells / Svetlana Ivanovna Galkina .. [et al.] -- Paracellular pores in endothelial barriers / Luca Manzi and Gianfranco Bazzoni -- Channels across endothelial cells / Radu V. Stan -- Molecular transfers through transient lymphoid cell-cell channels / Mary Poupot, Julie Gertner, and Jean-Jacques Fournié -- Cell-cell transport of homeoproteins: with or without channels / Alain Joliot and Alain Prochiantz -- Virological synapse for cell-cell spread of viruses / Eduardo Garcia and Vincent Piguet -- Cell-cell fusion: transient channels leading to plasma membrane merger / William A. Mohler.
  • Cell cycle activation in neurons: the final exit of brain-morpho-dysregulation / Thomas Arendt -- Paved with good intentions: the link between cell cycle and cell death in the mammalian central nervous system / Yan Yang and Karl Herrup -- The role of presenilins in the cell cycle and apoptosis / Mervyn J. Monteiro -- Cell cycle activation and cell death in the nervous system / Zsuzsanna Nagy -- Cell cycle and chromosome segregation defects in Alzheimer's disease / Huntington Potter -- Alzheimer disease-a new beginning or a final exit? / Mark E. Obrenovich ... [et al.] -- From cell cycle activation to the inhibition of the WNT pathway: a hypothesis of how neurons die in response to B-Amyloid / Agata Copani ... [et al.].
  • Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches. Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians.
  • Cellular origin and life in extreme habitats v. 1-4, 1999-2002., Springer
  • Cellular potts models 2013, CRCnetBASE
    "All biological phenomena emerge from an intricate interconnection of multiple processes occurring at different levels of organization: namely, at the molecular, the cellular and the tissue level, see Figure 1. These natural levels can approximately be connected to a microscopic, mesoscopic, and macroscopic scale, respectively. The microscopic scale refers to those processes that occur at the subcellular level, such as DNA synthesis and duplication, gene dynamics, activation of receptors, transduction of chemical signals, diffusion of ions and transport of proteins. The mesoscopic scale, on the other hand, can refer to cell-level phenomena, such as adhesive interactions between cells or between cells and ECM components, cell duplication and death and cell motion. The macroscopic scale finally corresponds to those processes that are typical of multicellular behavior, such as population dynamics, tissue mechanics and organ growth and development. It is evident that research in biology and medicine needs to work in a multiscale fashion. This brings many challenging questions and a complexity that can not be addressed in the classical way, but can take advantage of the increasing collaboration between natural and exact sciences (for more detailed comments the reader is referred to [90, 262]). On the other hand, the recent literature provides evidence of the increasing attention of the mathematical, statistical, computational and physical communities toward biological and biomedical modeling, consequence of the successful results obtained by a multidisciplinary approach to the Life Sciences problems"-- Provided by publisher.
  • Centromere 2009, Springer
  • Centrosome 2012, Springer
    Part I.Centrosomes in Reproduction --1.Centriole Duplication and Inheritance in Drosophila melanogaster /Tomer Avidor-Reiss, Jayachandran Gopalakrishnan, Stephanie Blachon and Andrey Polyanovsky --2.Sperm Centrioles and Their Dual Role in Flagellogenesis and Cell Cycle of the Zygote: Structure, Function, and Pathology /Hector E. Chemes --3.Centrosomal Functions and Dysfunctions in Cat Spermatozoa /Pierre Comizzoli and David E. Wildt --4.Nuclear-Centrosome Relationships During Fertilization, Cell Division, Embryo Development, and in Somatic Cell Nuclear Transfer Embryos /Heide Schatten and Qing-Yuan Sun --5.Human Centrosomal Dynamics During Gametogenesis, Fertilization, and Embryogenesis and Its Impact on Fertility: Ultrastructural Analysis /A. Henry Sathananthan --6.Asymmetric Centrosome Behavior in Stem Cell Divisions /Therese M. Roth, Yukiko M. Yamashita and Jun Cheng --Part II.Cell and Molecular Biology of Centrosomes --7.Functional Associations Between the Golgi Apparatus and the Centrosome in Mammalian Cells /Breanne Karanikolas and Christine Sütterlin --8.Many Pathways to Destruction: The Role of the Centrosome in, and Its Control by Regulated Proteolysis /Harold A. Fisk --9.Regulation of the Centrosome Cycle by Protein Degradation /Suzanna L. Prosser and Andrew M. Fry --10.Molecular Links Between Centrosome Duplication and Other Cell Cycle-Associated Events /Kenji Fukasawa --11.Regulation of Centrosomes by Cyclin-Dependent Kinases /Rose Boutros --Part III.Centrosome Abnormalities in Cancer --12.Disruption of Centrosome Duplication Control and Induction of Mitotic Instability by the High-Risk Human Papillomavirus Oncoproteins E6 and E7 /Nina Korzeniewski and Stefan Duensing --13.Centrosomes, DNA Damage and Aneuploidy /Chiara Saladino, Emer Bourke and Ciaran G. Morrison --14.Centrosome Regulation and Breast Cancer /Zeina Kais and Jeffrey D. Parvin --15.The Role of Centrosomes in Multiple Myeloma /Benedict Yan and Wee-Joo Chng --16.Centrosomal Amplification and Related Abnormalities Induced by Nucleoside Analogs /Ofelia A. Olivero --17.Mechanisms and Consequences of Centrosome Clustering in Cancer Cells /Alwin Krämer, Simon Anderhub and Bettina Maier --Part IV.Centrosomes in Other Systems --18.Re-evaluation of the Neuronal Centrosome as a Generator of Microtubules for Axons and Dendrites /Peter W. Baas and Aditi Falnikar --19.Centrosomes and Cell Division in Apicomplexa /Leandro Lemgruber, Marek Cyrklaff and Freddy Frischknecht --20.The Centrosome Life Story in Xenopuslaevis /Jacek Z. Kubiak and Claude Prigent --21.Role of the MTOC in T Cell Effector Functions /Martin Poenie, Laura Christian, Sarah Tan and Yuri Sykulev --22.Thoughts on Progress in the Centrosome Field /Jeffrey L. Salisbury.
  • Chembiomolecular science 2013, Springer
    At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chemical compounds as a probe. The second describes the biological approach used to develop new lead drug compounds. The third focuses on the biological system that serves as the potential drug target, the beginning step in the process of developing new drugs. Replete with the latest research, the book will draw the attention of all scientists interested in the synergies between chemistry and biology to elucidate life on a molecular level and to promote drug discovery. Ultimately, the book helps promote the understanding of biological functions at the molecular level and create new pharmaceuticals that can contribute to improving human health.
  • Chemical genomics 2006, Springer
  • Chromatin protocols. 2nd ed. 2009, Springer Protocols
    Preparation of chromatin assembly extracts from preblastoderm Drosophila embryos / Edgar Bonte and Peter B. Becker -- Analysis of reconstituted chromatin using a solid-phase approach / Raphael Sandaltzopoulos and Peter B. Becker -- In vivo chromatin decondensation assays : molecular genetic analysis of chromatin unfolding characteristics of selected proteins / Sherry L. Winter, Philip Wong, and Mark G. Alexandrow -- DNA methyltransferase probing of chromatin structure within populations and on single molecules / Carolina Pardo ... [et al.] -- Visualization of the expression of HMGN nucleosomal binding proteins in the developing mouse embryo and in adult mouse tissues / Takashi Furusawa and Michael Bustin -- Drug-induced premature chromosome condensation (PCC) protocols : cytogenetic approaches in mitotic chromosome and interphase chromatin / Eisuke Gotoh -- Analysis of DNA topology in yeast chromatin / Randall H. Morse -- Preparation and analysis of uniquely positioned mononucleosomes / Daria A. Gaykalova ... [et al.] -- Monitoring DNA breaks in optically highlighted chromatin in living cells by laser scanning confocal microscopy / Michael J. Kruhlak, Arkady Celeste, and André Nussenzweig -- Methods to study transcription-coupled repair in chromatin / Hélène Gaillard, Ralf Erik Wellinger, and Andrés Aguilera -- Cytometric analysis of DNA damage : phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs) / Toshiki Tanaka ... [et al.] -- Detection of DNA damage induced by topoisomerase II inhibitors, gamma radiation, and crosslinking agents using the comet assay / Lori A. Hazlehurst -- Analysis of genomic aberrations using comparative genomic hybridization of metaphase chromosomes / Melanie Carless -- In vitro replication assay with mammalian cell extracts / Wasia Rizwani and Srikumar P. Chellappan -- Investigation of genomic methylation status using methylation-specific and bisulfite sequencing polymerase chain reaction / Melanie Carless -- Biochemical analysis of arginine methylation in transcription / Marc Tini, Hina Naeem, and Joseph Torchia -- In vitro histone demethylase assays / Kenji Kokura and Jia Fang -- Histone chaperone as coactivator of chromatin transcription : role of acetylation / Shrikanth S. Gadad ... [et al.] -- Histone deacetylase activity assay / Zhigang Yuan ... [et al.] -- In vitro and in vivo assays for studying histone ubiquitination and deubiquitination / Ling Zhai, Heui-Yun Joo, and Hengbin Wang -- Detection of histone H3 phosphorylation in cultured cells and tissue sections by immunostaining / Jaya Padmanabhan -- Chromatin immunoprecipitation assays : analyzing transcription factor binding and histone modifications in vivo / Smitha Pillai, Piyali Dasgupta, and Srikumar P. Chellappan -- ChIP on Chip assays : genome-wide analysis of transcription factor binding and histone modifications / Smitha Pillai and Srikumar P. Chellappan -- ChIP-on-Chip analysis methods for Affymetrix tiling arrays / Sean J. Yoder and Steven A. Enkemann -- Non-radioactive assay methods for the assessment of telomerase activity and telomere length / Partha P. Banerjee and Shankar Jagadeesh -- Detecting ATM-dependent chromatin modification in DNA damage and heat shock response / Sandeep Misri, Shruti Pandita, and Tej K. Pandita.
  • Cilia, motors and regulation 2009, ScienceDirect
  • Cilia. Part A-B pt. A-B, 2013, ScienceDirect
    Pt. B ScienceDirect
  • Plants cannot move away from their environments. As a result, all plants that have survived to date have evolved sophisticated signaling mechanisms that allow them to perceive, respond, and adapt to constantly changing environmental conditions. Among the many cellular processes that respond to environmental changes, elevation of calcium levels is by far the most universal messenger that matches primary signals to cellular responses. Yet it remains unclear how calcium, a simple cation, translates so many different signals into distinct responses - how is the "specificity" of signal-re
  • Principles of model building : an experimentation-aided approach to development of models for signaling networks / Ambhighainath Ganesan and Andre Levchenko -- Integrated inference and analysis of regulatory networks from multi-level measurements / Christopher S. Poultney, Alex Greenfield, and Richard Bonneau -- Swimming upstream : identifying proteomic signals that drive transcriptional changes using the interactome and multiple "-omics" datasets / Shao-shan Carol Huang and Ernest Fraenkel -- A framework for modeling the relationship between cellular steady-state and stimulus-responsiveness / Paul M. Loriaux and Alexander Hoffmann -- Stochastic modeling of cellular networks / Jacob Stewart-Ornstein and Hana El-Samad -- Quantifying traction stresses in adherent cells / Casey M. Kraning-Rush ... [et al.] -- CellOrganizer : image-derived models of subcellular organization and protein distribution / Robert F. Murphy -- Spatial modeling of cell signaling networks / Ann E. Cowan ... [et al.] -- Stochastic models of cell protrusion arising from spatiotemporal signaling and adhesion dynamics / Erik S. Welf and Jason M. Haugh -- Nonparametric variable selection and modeling for spatial and temporal regulatory networks / Anil Aswani ... [et al.] -- Quantitative models of the mechanisms that control genome-wide patterns of animal transcription factor binding / Tommy Kaplan and Mark D. Biggin -- Computational analysis of live cell images of the Arabidopsis thaliana plant / Alexandre Cunha ... [et al.] -- Multi-scale modeling of tissues using CompuCell3D / Maciej H. Swat ... [et al.] -- Multiscale model of fibrin accumulation on the blood clot surface and platelet dynamics / Zhiliang Xu ... [et al.].
  • Communication in the immune system by connexin channels / E. Oviedo-Orta and W. Howard Evans -- Gap junctions and connexins in the hematopoietic-immune system : structural considerations / T. Krenacs, I. Zsakovics and M. Rosendaal -- Approaches for studying the role(s) of gap junctions in the immune system / A.M. Glass, T.D. Nguyen, S. Taffet -- Gap junctions in antigen presenting cells / P.J. Saez, K.F. Shoji, J.C. Saez -- Connect the immune system : roles of gap junctions in antigen presentation and T cell activation / B. Pang, J. Neefjes -- Gap junctions and connexins in the immune defence against tumors / F. Salazar-Onfray -- Connexins in atherosclerosis / L. Burnier, B.R. Kwak -- Connexins in lung function and inflammation / M. Chanson, M. Koval -- The effect of oxidative stress on connexins in the vasculature / M. Billaud ... [et al.] -- The regulation of gap junctions and cellular coupling within the microvasculature in response to acute inflammation / D. Lidington, K. Tyml -- Impact of microglial activation on astroglial connexin expression and function in brain inflammation / C. Giaume ... [et al.] -- A role for connexins in inflammatory disorders of the epidermis / S. Donnelly, P. Martin -- Translating basic research on Cx43 gap junctions into therapies for reducing scarring and cardiac arrhythmia / J.M. Rhett ... [et al.] -- Connexin-based therapeutic approaches to inflammation in the central nervous system / J. Zhang ... [et al.] -- Enhancing epithelial tissue repair and reducing inflammation by targeting connexins / D.L. Becker ... [et al.].
  • ch. 1. Cell Culture -- ch. 2. Preparation and Isolation of Cells -- ch. 3. Subcellular Fractionation and Isolation of Organelles -- ch. 4. Microscopy -- ch. 5. Characterization of Cellular Proteins -- ch. 6. Electrophoresis and Immunoblotting -- ch. 7. Protein Labeling and Immunoprecipitation -- ch. 8. Cell Cycle Analysis -- ch. 9. Cell Adhesion -- ch. 10. Extracellular Matrix -- ch. 11. In Vitro Reconstitution -- ch. 12. Cell Motility -- ch. 13. Organelle Motility -- ch. 14. Signal Transduction: Protein Phosphorylation -- ch. 15. Protein Trafficking -- ch. 16. Antibodies as Cell Biological Tools -- ch. 17. Macromolecular Interactions in Cells -- ch. 18. Cellular Aging and Death -- ch. 19. Whole Organism and Tissue Analysis -- ch. 20. Expression and Introduction of Macromolecules into Cells -- ch. 21. Fluorescent Protein Technology -- ch. 22. Cell Biology of Chromosomes and Nuclei -- ch. 23. Stem Cells -- ch. 24. Lipids -- ch. 25. Nanotechnology -- ch. 26. Viruses -- ch. 27. RNA-Based Methods in Cell Biology -- Appendix 1. Useful Information and Data -- Appendix 2. Laboratory Stock Solutions and Equipment -- Appendix 3. Commonly Used Techniques -- Appendix. Suppliers.
  • Consists of a core publication dated Apr. 1997, and updated by supplements 1 (July 1997)-<57 (July 2010)>. Content is peer-reviewed protocols for flow and image cytometry updated quarterly.
  • Includes methods for isolating, maintaining, and differentiating embryonic and adult stem cells.
  • Cytokines 2011, CRCnetBASE
  • In recent decades, cytopathology has assumed an increasing role in the primary diagnosis of mass lesions owing to its ability to provide rapid, non-invasive, and timely information. With cytopathology at the forefront of diagnosis and prognostication of neoplastic lesions, it is essential that physicians involved in the diagnosis and treatment of precancerous lesions and cancer have a clear understanding of specimen collection techniques, terminology for reporting, and outcomes in various diagnostic categories. This book provides a comprehensive overview of the role of cytology at various body sites. The diagnostic details covered are abbreviated in comparison with those in pathology texts. Instead, a more clinical approach is taken, with the focus on the advantages and limitations of techniques and the key features of entities that are important to clinicians. Pathological clinical correlation is highlighted throughout the book, ensuring that it will be highly relevant for clinicians. In particular, physicians who deal with oncology patients will find it to be a rich source of guidance on how to use and understand cytopathology in the diagnosis and exclusion of malignancy.
  • & Quot;Soft Tissue Cytopathology" by Anil V. Parwani, MD, PhD and Walid E. Khalbuss, MD, PhD, will fulfill the need for an easy-to-use and authoritative synopsis of soft tissue cytopathology. This volume, part of "The Essentials in Cytopathology book series," fits into the lab coat pocket and is ideal for portability and quick reference. Each volume in the series is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. Anil V. Parwani, MD, PhD, is Associate Professor of Pathology at the University of Pittsburgh Medical Center - S.
  • Cytopreparation 2013, Springer
    Cytopreparation: Principles & Practice by Gary W. Gill fills a long-standing need for an easy-to-use and authoritative manual on the fundamentals of cytopreparation up-to-and- including microscopy, screening, and data analysis. The text describes in phenomenological terms the most common materials and methods of specimen collection through mounting for gyn, non-gyn, and FNA specimens, as well as the underlying mechanistic bases. The author provides his expertise and information that will empower and enable readers to review and improve their laboratories' cytopreparatory techniques as they apply to the vast majority of specimens. This unique volume provides facts that are not readily available anywhere. Cytopreparation: Principles & Practice is intended for everyone associated with, and involved in, making cytologic preparations that are useful for their intended purpose. It will serve as a valuable reference tool for educators in cytology and histology, cytotechnology and histotechnology students, cytotechnologists, cytopreparatory technicians, cytopathologists, anatomical/clinical pathologists, pathology residents and cytopathology fellows.
  • Central axonal development and pathology in early life / Robin L. Haynes and Hannah C. Kinney -- Microtubules in the nervous system / Nobuyuki Fukushima -- Tau phosphorylation / Jesús Avila and Félix Hernández -- Tau pathology / Nicolas Sergeant and Luc Buée -- Tauopathy and brain aging / Akihiko Takashima -- Microtubule-associated protein 4 / Kiyotaka Tokuraku ... [et al.] -- Structure of neural intermediate filaments / David A.D. Parry -- Alpha-internexin: the fourth subunit of neurofilaments in the mature CNS / Aidong Yuan and Ralph A. Nixon -- Peripherin pathology / Jesse R. McLean and Janice Robertson -- Neurofilament cross-bridge: a structure associated specifically with the neurofilament among the intermediate filament family / Takahiro Gotow -- Neurofilament transport / Andrew J. Grierson and Christopher C.J. Miller -- Knockout models of neurofilament proteins / Rodolphe Perrot and Jean-Pierre Julien -- Neurofilaments and radial growth: deconstruction of a hypothesis through the construction of gene targeted mice / Michael L. Garcia and Devin M. Barry -- Deregulation of cytoskeletal protein phosphorylation and neurodegeneration / Jyotshnabala Kanungo ... [et al.] -- Neurofilaments in aged animals / Shin-ichi Hisanaga, Takahiro Sasaki, and Atsuko Uchida -- Neurofilament changes in multiple sclerosis / Elizabeth Gray and Alastair Wilkins -- Intermediate filament interactions in neurons / Kevin G. Young and Rashmi Kothary -- Tropomyosins in neuronal morphogenesis and development / Nikki Margarita Curthoys, Peter William Gunning, and Thomas Fath -- The driving machinery for growth cone navigation / Takuro Tojima and Hiroyuki Kamiguchi -- Glial fibrillary acidic protein: the intermediate filament protein of astrocytes / Douglas L. Eng and Lawrence F. Eng -- Axonal transport mechanisms in cytoskeleton formation and regulation / Aidong Yuan and Ralph A. Nixon -- Axonal transport and motor neuron disease / Anna-Lena Ström ... [et al.] -- In vivo imaging of axonal transport in aging and Alzheimer's disease / Donna J. Cross and Satoshi Minoshima -- Regulation of cytoskeletal composition in neurons: transcriptional and post-transcriptional control in development, regeneration, and disease / Ben G. Szaro and Michael J. Strong -- Crosstalks between myelinating cells and the axonal cytoskeleton / Rodolphe Perrot and Joël Eyer -- Topographic regulation of neuronal intermediate filament proteins by phosphorylation: in health and disease / Parvathi Rudrabhatla and Harish C. Pant -- Cytoskeleton, axonal transport, and the mechanisms of axonal neuropathy / Hsinlin T. Cheng ... [et al.] -- Effects of insulin on tau and neurofilament / R. Schechter and K.E. Miller -- Ethanol effects on the cytoskeleton of nerve tissue cells / Sergio G. Evrard and Alicia Brusco.
  • The role of TNF in cancer / Harald Wajant -- Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses / Madhu Ramaswamy ... [et al.] -- FasL expression and reverse signaling / M. Lettau ... [et al.] -- Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling / Stefan Schütze and Wulf Schneider-Brachert -- Ubiquitination and TNFR1 signaling / Ken-ichi Fujita and Srinivasa M. Srinivasula -- From biochemical principles of apoptosis induction by TRAIL to application in tumour therapy / Stefanie M. Cordier, Kerstin Papenfuss, and Henning Walczak -- Therapeutic targeting of TWEAK/Fn14 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway / Jennifer S. Michaelson and Linda C. Burkly -- APRIL in B-cell malignancies and autoimmunity / Fiona C. Kimberly, Jan Paul Medema, and Michael Hahne -- Autophagy in cancer and chemotherapy / Shida Yousefi and Hans-Uwe Simon -- Glucocorticoid-mediated apoptosis resistance of solid tumors / Ingrid Herr, Markus W. Büchler, and Jürgen Mattern -- Targeting death-receptors in radiation therapy / Olivier Niemöller and Claus Belka -- Death ligands designed to kill: development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands / Jeannette Gerspach, Harald Wajant, and Klaus Pfizenmaier.
  • Dental pulp stem cells 2013, Springer
    Dental Evolution -- Tooth development -- Dental Pulp is a Connective Tissue -- Dental Pulp Stem Cells (DPSC) -- Isolation methods of DPSC -- Characterization of DPSC -- Reprogramming of DPSC to induced pluripotent stem cells (iPSC) -- Immunomodulatory effects of DPSC -- Dental Pulp is a Complex Adaptive System.
  • Following their own brilliant careers in haeme protein research, the outstanding scientists Jonathan and Beatrice Wittenberg continue to provide inspiration to the research community in the study of oxygen-binding proteins. Their research has provided the intellectual stimulus to bring together scientists from all over the world with the common goal of developing fascinating new ideas and performing innovative experiments. This book is dedicated to Jonathana (TM)s and Beaa (TM)s lifetime careers. It further illuminates the facts and ideas which dot the paths they traced in Biochemistry and Physiology, elaborating on how these landmark achievements were made and how the haeme proteins community still refers to them. With the field of haeme protein science such a flourishing area, the contributors to this book predict Jonathan and Bea, having played such a seminal role, will continue to be key figures for quite some time to come.
  • The secretory capacity of a cell depends on the efficiency of endoplasmic reticulum-associated degradation / M. Molinari and R. Sitia -- Recognition and delivery of ERAD substrates to the proteasome and alternative paths for cell survival / A.A. McCracken and J.L. Brodsky -- CPY* and the power of yeast genetics in the elucidation of quality control and associated protein degradation of the endoplasmic reticulum / D.H. Wolf and A. Schäfer -- The role of the ubiquination machinery in dislocation and degradation of endoplasmic reticulum proteins / M. Kikkert, G. Hassink, and E. Wiertz -- The role of p97/Cdc48p in endoplasmic reticulum-associated degradation : from the immune system to yeast / S. Bar-Nun -- The ins and outs of intracellular peptides and antigen presentation by MHC Class I molecules / T. Groothuis and J. Neefjes -- Entry of protein toxins into mammalian cells by crossing the endoplasmic reticulum membrane : co-opting basic mechanisms of endoplasmic reticulum-associated degradation / J.M. Lord , L.M. Roberts, and W.I. Lencer.
  • The existence of 'cancer stem cells' (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types.
  • Dyneins. 1st ed. 2012, ScienceDirect
    Research on dyneins has a direct impact on human diseases, such as viruses and cancer. With an accompanying website showing over one hundred streaming videos of cell dynamic behavior for best comprehension of material, Dynein: Structure, Biology and Disease is the only reference covering the structure, biology and application of dynein research to human disease. From bench to bedside, Dynein: Structure, Biology and Disease offers research on fundamental cellular processes to researchers and clinicians across developmental biology, cell biology, molecular biology, biophysics, biomedicine, genetics and medicine. . Broad-based up-to-date resource for the dynein class of molecular motors . Chapters written by world experts in their topics . Numerous well-illustrated figures and tables included to complement the text, imparting comprehensive information on dynein composition, interactions, and other fundamental features.
  • ECTO-NOX proteins 2013, Springer
    "ENOX Proteins" documents a unique family of cell surface proteins which are the exclusive discovery (subsequently confirmed by others) of the authors, their students and their colleagues. An ENOX-based mechanism is provided for how cells increase in size that is both unique and applicable not only to cancer and cancer therapy but also to production agriculture and biomass increase. The role of ENOX proteins in biological time-keeping is described along with evidence for oscillations in the ratios of electron spin pairs defining ortho and para water states that form highly coordinated populations of coherent water of interest to physicists as the underlying mechanism. The age-related NADH oxidases that appear around age 30 and increase steadily thereafter with potentially causal involvements in atherogenesis and skin aging have been identified as five members of the TM-9 protein superfamily of all with different chromosomal locations. The arNOX proteins initially are membrane anchored but functionally-active N-terminal fragments that are shed into body fluids. Except for critical functional motifs, all of the ENOX protein family members have distinct protein sequences and chromosomal origins. A fourth member of the ENOX protein family occurs in plants as the primary target for both natural and synthetic growth hormone (auxin)-stimulated rapid cell enlargement. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins offer remarkable opportunities for research, commercial development and outside confirmation of new paradigms to help explain complex biological processes.
  • Electric Cell-Substrate Impedance Sensing Concept to Commercialization /Ivar Giaever and Charles R. Keese --Protein Kinase C Isoforms in the Formation of Focal Adhesion Complexes: Investigated by Cell Impedance /Havovi Chichger, Katie L. Grinnell and Elizabeth O. Harrington --ECIS as a Tool in the Study of Metastasis Suppressor Genes: Epithelial Protein Lost In Neoplasm (EPLIN) /Andrew J. Sanders, Vladimir M. Saravolac, Malcolm D. Mason and Wen G. Jiang --Electrical Cell-Substrate Impedance Sensing for Measuring Cellular Transformation, Migration, Invasion, and Anticancer Compound Screening /Bryan Plunger, Chang Kyoung Choi and Tim E. Sparer --Epithelial-Mesenchymal Transition and the Use of ECIS /Jane Lane and Wen G. Jiang --Cell Growth and Cell Death Studied by Electric Cell-Substrate Impedance Sensing /Judith Anthea Stolwijk, Stefanie Michaelis and Joachim Wegener --Tight Junctions in Cancer Metastasis and Their Investigation Using ECIS (Electric Cell-Substrate Impedance Sensing) /Tracey A. Martin and Wen G. Jiang --Epithelial Wound Healing and the Effects of Cytokines Investigated by ECIS: Electric Cell-Substrate Impedance Sensing in Epithelial Research /Katalin Szaszi, Matthew Vandermeer and Yasaman Amoozadeh --Tumour-Endothelial and Tumour-Mesothelial Interactions Investigated by Impedance Sensing Based Cell Analyses /Wen G. Jiang, Lin Ye, Haiying Ren, Ann Kift-Morgan and Nicholas Topley, et al. --Application of Electric Cell-Substrate Impedance Sensing in Evaluation of Traditional Medicine on the Cellular Functions of Gastric and Colorectal Cancer Cells /Lin Ye, Ke Ji, Jiafu Ji, Rachel Hargest and Wen G. Jiang --Electric Cell-Substrate Impedance Sensing as a Screening Tool for Wound Healing Agents /Cheuk Lun Liu, Jacqueline Chor Wing Tam, Andrew J. Sanders, David G. Jiang and Chun Hay Ko, et al. --ECIS, Cellular Adhesion and Migration in Keratinocytes /David C. Bosanquet, Keith G. Harding and Wen G. Jiang --Current and Future Applications of ECIS Models to Study Bone Metastasis /Lin Ye, Sivan M. Bokobza, Howard G. Kynaston and Wen G. Jiang.
  • Chapter 1. Electron Microscopy of Viruses -- Chapter 2. Bacterial TEM : New Insights from Cryo-Microscopy -- Chapter 3. Analysis of the Ultrastructure of Archaea by Electron Microscopy -- Chapter 4. Chlamydomonas : Cryopreparation Methods for the 3-D Analysis of Cellular Organelles -- Chapter 5. Ultrastructure of the Asexual Blood Stages of Plasmodium falciparum -- Chapter 6. Electron Tomography and Immuno-labeling of Tetrahymena thermophila Basal Bodies -- Chapter 7. Electron Microscopy of Paramecium (Ciliata).
  • Embryonic stem cell protocols. 2nd ed. v. 1-2, 2006, Springer Protocols
    v. 2, 2006 Springer Protocols
    v. 1. Isolation and characterization -- v. 2. Differentiation models.
  • Embryonic stem cells 2006, ScienceDirect
    Derivation and maintenance of embryonic stem cells -- Differentiation of embryonic stem cells.
  • Embryonic stem cells 2007, Springer
    Defined culture media for human embryonic stem cells / T. Ludwig and J. Thomson -- Generation of disease-specific human embryonic stem cell lines / S. Minger -- Characterization and differentiation of human embryonic stem cells / A. Laslett ... [et al.] -- Genetic modification of human embryonic stem cells / T. Zwaka -- Hematopoietic differentiation / C. Cerdan ... [et al.] -- Neural differentiation / Z.-J. Zhang ... [et al.] -- Germ cell differentiation / V. Angeles and R. Pera -- Mesodermal differentiation / N. Sharon and N. Benvenisty -- Three-dimensional culture of human embryonic stem cells / S. Gerecht ... [et al.] -- Extraembryonic cell differentiation / L. Armstrong and M. Lako -- Pancreatic cell differentiation / B. Fishman ... [et al.] -- Cardiomyocyte differentiation / D. Singla ... [et al.] -- Human embryonal carcinoma (EC) cells: Complementary tools for embryonic stem cell research / P. Tonge and P. Andrews -- Quality control of human stem cell lines / G. Stacey.
  • Volume 1. 0-9-F -- volume 2. G-O -- volume 3. P-Z.
  • The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions. It is the organelle responsible for protein folding, maturation, quality control and trafficking of proteins destined for the plasma membrane or for secretion into the extracellular environment. Failure, overloading or malfunctioning of any of the signaling or quality control mechanisms occurring in the ER may provoke a stress condition known as âER stressâ. Accumulating evidence indicates that ER stress may dramatically perturb interactions between the cell and its environment, and contribute to the development of human diseases, ranging from metabolic diseases and cancer to neurodegenerative diseases, or impact therapeutic outcome. This book primarily focuses on the pathophysiology of ER stress. It introduces the molecular bases of ER stress, the emerging relevance of the ER-mitochondria cross-talk, the signaling pathways engaged and cellular responses to ER stress, including the adaptive Unfolded Protein Response (UPR), autophagy as well as cell death. Next the book addresses the role of ER stress in physiology and in the etiology of relevant pathological conditions, like carcinogenesis and inflammation, neurodegeneration and metabolic disease. The last chapter describes how ER stress pathways can be targeted for therapeutic benefit. Altogether, this book will provide the reader with an exhaustive view of ER stress biology and the latest insights in the role of ER stress in relevant human diseases.
  • Endosome signalling. Part A-B. First edition. pt. A-B, 2014, ScienceDirect
    Pt. B ScienceDirect
  • Endothelial cytoskeleton 2014, CRCnetBASE
    The endothelial cytoskeleton : multifunctional role of the endothelial actomyosin cytoskeleton / Yuka Shimizu and Joe G.N. Garcia -- Emerging themes on pulmonary microvascular endothelial cell : microtubules and microtubule associated proteins / Cristiaan D. Ochoa, Ron Balczon, and Troy Stevens -- Endothelial actin cytoskeleton and angiogenesis / Sadiqa K. Quadri -- Adherens junctions and endothelial cytoskeleton / Younes Smani and Tarik Smani-Hajami -- Mechanical force transmission via the cytoskeleton in vascular endothelial cells / Bori Mazzag ... [et al.] -- The functional role of the microtubule/microfilament cytoskeleton in the regulation of pulmonary vascular endothelial barrier / Irina B. Alieva and Alexander D. Verin -- Membrane-cytoskeleton interactions and control of vesicle trafficking in endothelial cells / Felicia Antohe -- Cell-matrix adhesion proteins in the regulation of endothelial permeability / Jurjan Aman, Geerten P. van Nieuw Amerongen, and Victor W.M. van Hinsbergh -- Endothelial cells and the regulation of platelet function / P.C. Redondo ... [et al.].
  • Epithelial cell culture protocols 2002, Springer Protocols
  • Erythropoiesis: an overview / B.E. Torbett and J.S. Friedman -- Regulation of endogenous erythropoietin production / D.R. Mole and P.J. Ratcliffe -- Biology of erythropoietin / G. Molineux and A.M. Sinclair -- Erythropoiesis - genetic abnormalities / J.T. Prchal and X.T. Gregg -- Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin / M.A. Foote -- Commercial production of recombinant erythropoietins / A.S. Chuck ... [et al.] -- Biosimilar epoetins / H. Schellekens -- New molecules and formulations / S.G. Elliott -- Structural basis for the signal transduction of erythropoietin / T.D. Osslund -- Intracellular signaling by the erythropoietin receptor / H.F. Lodish ... [et al.] -- Mechanism of erythropoietin receptor activation / S.N. Constantinescu -- Pharmacokinetics of erythropoiesis-stimulating agents / S. Doshi ... [et al.] -- Use of erythropoietic stimulating agents in the setting of renal disease / D.A. Goodkin -- Abuse of recombinant erythropoietins and blood products by athletes / D.H. Catlin and C.K. Hatton -- Role and regulation of iron metabolism in erythropoiesis and disease / T.L. Arvedson and B.J. Sasu -- Nonhematopoietic effects of erythropoiesis-stimulating agents / W. Jelkmann, R. Depping and E. Metzen.
  • Introduction to stem cells -- Basic biology/mechanisms -- Tissue and organ development -- Methods -- Applications -- Regulation and ethics.
  • Pt. 1. Research biobanking : the traditional approach -- Consent to biobank research : one size fits all? / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- What no one knows cannot hurt you : the limits of informed consent in the emerging world of biobanking / Arthur L. Caplan -- Users and uses of the biopolitics of consent : a study of DNA banks / Pascal Ducournau and Anne Cambon-Thomsen -- Information rights on the edge of ignorance / Anne Maria Skrikerud -- The dubious uniqueness of genetic information / Anne Maria Skrikerud -- Duties and rights of biobank participants : principled autonomy, consent, voluntariness and privacy / Lars Øystein Ursin -- Biobanking and disclosure of research results : addressing the tension between professional boundaries and moral intuition / Lynn G. Dressler -- Biobanks and our common good / Erik Christensen -- Trust, distrust and co-production : the relationship between research biobanks and donors / Pascal Ducournau and Roger Strand -- Scientific citizenship, benefit, and protection in population-based research / Vilhj́almur Árnason -- Pt. 2. Research Biobanking : towards a new conceptual approach -- Mapping the language of research biobanking : an analogical approach / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- The use of analogical reasoning in umbilical cord blood biobanking / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- The Alexandria plan : creating libraries for human tissue research and therapeutic use / Laurie Zoloth -- The art of biocollections / Anne Hambro Alnæs -- The health dugnard : biobank participation as the solidary pursuit of the common good / Lars Øystein Ursin and Berge Solberg -- Embodied gifting : reflections on the role of information in biobank recruitment / Klaus Hoeyer -- Conscription to biobank research? / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- Ownership rights in research biobanks : do we need a new king of 'biological property'? / Paula Lobato de Faria -- Legal challenges and strategies in the regulation of research biobanking / Elisabeth Rynning -- Annexation of life : the biopolitics of industrial biology / Jan Reinert Karlsen and Roger Strand -- In the ruins of Babel : should biobank regulations be harmonized / Jan Reinert Karlsen, Jan Helge Solbak, and Roger Strand.
  • The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
  • Extracellular matrix 2011, Springer
    An overview of extracellular matrix structure and function /Jürgen EngelandMatthias Chiquet --Fibronectin and other adhesive glycoproteins /Jielin XuandDeane Mosher --Collagens, suprastructures, and collagen fibril assembly /David E. BirkandPeter Brückner --Basement membranes /Jeffrey H. Miner --Hyaluronan and the aggregating proteoglycans /Thomas N. Wight,Bryan P. Toole,andVincent C. Hascall --Small leucine-rich proteoglycans /Renato V. Iozzo... [et al.] --Microfibrils and fibrillin /Dirk HubmacherandDieter P. Reinhardt --Elastin /Beth A. Kozel,Robert P. Mecham,andJoel Rosenbloom --Lysyl oxidase and lysyl oxidase-like enzymes /Herbert M. KaganandFaina Ryvkin --The fibulins /Marion A. CooleyandW. Scott Argraves --Matricellular proteins /David D. RobertsandLester F. Lau.
  • Matrix metalloproteinases and their inhibitors in turnover and degradation of extracellular matrix / Sean E. Gill and William C. Parks -- Role of cysteine cathepsins in extracellular proteolysis / Dieter Brömme and Susan Wilson -- Cooperation between proteolysis and endocytosis in collagen turnover / Thomas H. Bugge and Niels Behrendt -- Pericellular proteolysis / Judith S. Bond, Timothy R. Keiffer, and Qi Sun -- Triple helicase activity and the structural basis of collagenolysis / Hideaki Nagase and Robert Visse -- Structural basis of extracellular matrix interactions with matrix metalloproteinases / Steven R. Van Doren -- The role of matrix metalloproteinases in cellular invasion and metastasis / Elena I. Deryugina and James P. Quigley -- Degradation of bone and the role of osteoclasts, bone lining cells and osteocytes / Vincent Everts and Paul Saftig -- Consequences of elastolysis / A. McGarry Houghton, Majd Mouded, and Steven D. Shapiro.
  • Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix - secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
  • Introduction and historical perspective -- FNAC technique and slide preparation -- Diagnostic interpretation of FNAC material -- Diagnostic dilemmas in FNAC practice: cystic lesions -- Diagnostic dilemmas in FNAC practice: lymphoid infiltrates -- Diagnostic dilemmas in FNAC practice: metastatic tumours -- Diagnostic dilemmas in FNAC cytology: small round cell tumours -- Diagnostic dilemmas in FNAC cytology: soft-tissue lesions -- Diagnostic dilemmas in FNAC cytology: difficult breast lesions -- Principles of safe practice: the role of FNAC in clinical management -- Principles of safe FNAC practice: FNAC versus core biopsy -- Principles of safe FNAC practice: medicolegal issues.
  • Flow cytometry 2007, Springer
    Principles of flow cytometry / Marion G. Macey -- Cell preparation / Desmond A. McCarthy -- Fluorochromes and fluorescence / Desmond A. McCarthy -- Quality control in flow cytometry / David Barnett and John T. Reilly -- Experimental design, data analysis, and fluorescence quantitation / Mark Lowdell -- Apoptosis detection by flow cytometry / Paul Allen and Derek Davies -- DNA analysis by flow cytometry / Derek Davies and Paul Allen -- Immunological studies of human cells / Ulrika Johansson -- Calcium: cytoplasmic, mitochondrial, endoplasmic reticulum, and flux measurements / Gary Warnes and Marion G. Macey -- Further functional studies / Marion G. Macey -- Cell sorting by flow cytometry / Derek Davies.
  • Flow cytometry protocols. 2nd ed. 2004, Springer Protocols
    Flow cytometry : an introduction / Alice L. Givan -- Multiparameter flow cytometry of bacteria / Howard M. Shapiro and Gerhard Nebe-von-Caron -- Multiparameter data acquisition and analysis of leukocytes / Carleton C. Stewart and Sigrid J. Stewart -- Flow cytometric analysis of kinase signaling cascades / Omar D. Perez, Peter O. Krutzik, and Garry P. Nolan -- Cytokine flow cytometry / Holden T. Maecker -- Use of cell-tracking dyes to determine proliferation precursor frequencies of antigen-specific T cells / Alice L. Givan ... [et al.] -- Assessment of lymphocyte-mediated cytotoxicity using flow cytometry / Luzheng Liu ... [et al.] -- Multiparametric analysis of apoptosis by flow and image cytometry / William G. Telford, Akira Komoriya, and Beverly Z. Packard -- Detection and enrichment of hematopoietic stem cells by side population phenotype / Shannon S. Eaker ... [et al.] -- Hematopoietic stem cell characterization by Hoechst 33342 and Rhodamine 123 staining / Ivan Bertoncello and Brenda Williams --Phenotypic and functional analyses of human CD34neg hematopoietic precursors from mobilized peripheral blood / Douglas C. Dooley and Barbara K. Oppenlander -- Multiparameter flow cytometry of fluorescent protein reporters / Teresa S. Hawley ... [et al.] -- Analysis of fluorescent protein expressing cells by flow cytometry / Steven C. Pruitt, Lawrence M. Mielnicki, and Carleton C. Stewart -- Integrative flow cytometric and microarray approaches for use in transcriptional profiling / David W. Galbraith, Rangasamy Elumalai, and Fang Cheng Gong -- Flow cytometric analysis of fluorescence resonance energy transfer : a tool for high-throughput screening of molecular interactions in living cells / Francis Ka-Ming Chan and Kevin L. Holmes -- Design of a fluorescence-activated cell sorting-based mammalian protein-protein interaction trap / Sam Lievens ... [et al.] -- Flow cytometric screening of yeast surface display libraries / Michael Feldhaus and Robert Siegel -- Fluorescence resonance energy transfer based HIV-1 virion fusion assay -- Marielle Cavrois ... [et al.] -- Cell cycle analysis of asynchronous populations / Michael G. Ormerod -- Solid tumor DNA content analysis / Adel K. El-Naggar and Philippe Vielh --Concurrent flow cytometric analysis of DNA and RNA / Adel K. El-Naggar -- Telomere length measurement by fluorescenece in situ hybridization and flow cytometry / Veena Kapoor and William G. Telford -- Small lasers in flow cytometry / William G. Telford -- Viable infectious cell sorting in a BSL-3 facility / Stephen P. Perfetto ... [et al.].
  • Folding for the synapse 2011, Springer
    Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.
  • A short dictionary of the Pap test -- Analogies in the Pap test : "Of corn flakes and raisins" -- Basic cytology principles -- Basic anatomy and cytology of the female genital tract -- The Bethesda system -- Liquid-based cytology -- Physiological cytology -- Reactive changes and organisms -- Human papillomavirus in cervical carcinogenesis -- Atypical squamous cells -- Low-grade squamous intra-epithelial lesion -- High-grade squamous intra-epithelial lesion -- Invasive squamous carcinoma -- Endocervical lesions -- Endometrial lesions -- Metastatic tumors -- Therapy-related changes -- Artifacts, contaminants, and incidental findings -- Screening and management guidelines of Pap test and newer techniques.
  • This Brief offers a concise, handy overview of the main concepts related to Embryology, revisited through the novel concepts that are applied daily in stem cell research and cell therapy oriented investigations. It is based on three main areas: -The process involved in female gamete differentiation and maturation. The main aspects related to cell biology will be covered and an overview of the epigenetic regulation of gametogenesis will be presented. -Early stages of embryo development with a careful analysis of the regulatory mechanisms driving cleavage, polarization and genome activation. -Stem cell and gametogenesis. The use of the oocyte as a possible source for the derivation of stem cell lines is discussed and depicted as a powerful tool to investigate oocyte potency and asymmetric imprinting. The potential biological implications are evaluated and use of stem cells to derive oocytes is presented.
  • Gasotransmitters 2012, Springer
    "The gases termed gasotransmitters play an increasingly important role in understanding how signalling into and between cells is modulated and fine-tuned. The advent of gasotransmitters has profoundly changed our way of thinking about biosynthesis, liberation, storage and action mechanisms in cellular signaling. In recent years an impressive amount of new data, distributed throughout the existing literature, has been generated. For this book the editors have recruited distinguished colleagues in the field to summarize and review important biological, pharmacological and medical functions and their implications, as well as methods for the detection of gasotransmitters."--P. [4] of cover.
  • Genome integrity 2007, Springer
    From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. It begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. It also reviews the cellular responses to radiation and genotoxic stress affecting whole genomes.
  • Glioma signaling 2013, Springer
  • Heparan sulfate proteoglycan in inflammation and angiogenesis / Lianchun Wang -- Heparan sulfate proteoglycans in infection / Allison H. Bartlett and Pyong Woo Park -- Glycans in cancer / Lubor Borsig -- Glycosaminoglycans in atherosclerosis and thrombosis / C.P. Vicente, J.A.P. Godoy, and C.C. Werneck -- Glycans in embryonic stem cells / Claire Pickford ... [et al.] -- Heparan sulfate proteoglycans in cancer therapy / Ezeddin Salem Gassar, Sherif A. Ibrahim, and Martin Götte -- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates : new therapeutic agents? / Eliene O. Kozlowski ... [et al.]
  • GTPase protocols 2002, Springer Protocols
  • Hair follicle 2005, Springer
  • Handbook of dynein 2012, CRCnetBASE
    "This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give readers a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. This is a useful handbook for frontline researchers as well as a textbook for advanced students."--P. [4] of cover.
  • "Reflecting the milestones in the field that have occurred since the publication of the first edition, this book provides an updated tool kit that incorporates conventional as well as modern approaches to tackling biological and medicinal research in the post genomic era. The authors have evaluated, revised, and sometimes replaced all protocols with more efficient, reliable, or simpler ones. The book is also completely reorganized and covers topics of modern "omics" approaches, including genomics, proteomics, and metabolomics. This is followed coverage of the Manipulation of Biological Systems, including RNAi, and the use of microscopy"--Provided by publisher.
  • Quality management and regulation / Jeffrey Prichard -- Technique and troubleshooting of antibody testing / Fan Lin and Jianhui Shi -- Overview of automated immunohistochemistry / Jeffrey Prichard, Angela Bitting, and Joe Myers -- Automated staining : Dako perspective / Ole F. Rasmussen and Andreas Schønau -- Automated staining : Ventana perspective / Angela Sattler -- Tissue microarray / Myra Wilkerson and Erin Powell -- Unknown primary/undifferentiated neoplasms in surgical and cytologic specimens / Fan Lin and Haiyan Liu -- Exfoliative cytopathology / Steven Meschter and Jan F. Silverman -- Predictive markers of breast cancer : ER, PR, and HER2 / Jeffrey Prichard, David Hicks, and Elizabeth Hammond -- Central and peripheral nerve system tumors / Hueizhi (Hope) Wu, Conrad Schuerch, and Douglas C. Miller -- Thyroid and parathyroid gland / Haiyan Liu, Fan Lin, and Ronald A. DeLellis -- Adrenal gland / Hanna G. Kaspar -- Salivary gland and other head and neck structures / Conrad Schuerch -- Lung, pleura, and mediastinum / Kai Zhang and Phillip Cagle -- Breast / Haiyan Liu -- Uterus / Hanna G. Kaspar -- Ovary / Jeffrey Prichard, Haiyan Liu, and Myra Wilkerson -- Prostate gland / Haiyan Liu, Fan Lin, and Qihui (Jim) Zhai -- Urinary bladder / Myra Wilkerson -- Kidney / Fan Lin and Ximing J. Yang -- Testis and paratesticular tissues / Myra Wilkerson -- Pancreas and ampulla / Fan Lin and Hanlin L. Wang -- Liver, bile ducts, and gallbladder / Jeffrey Prichard and Fan Lin -- Upper gastrointestinal tract / Jinhong Li and Fan Lin -- Lower gastrointestinal tract and microsatellite instability / Jinhong Li and Fan Lin -- Soft tissue and bone tumors / Shaobo Zhu and Markku Miettinen -- Lymph node / Xiaohong (Mary) Zhang and Nadine S. Aguilera -- Bone marrow / R. Patrick Dorion and Xiaohong (Mary) Zhang -- Infectious diseases / Dirk M. Elston, Lawrence E. Gibson, and Heinz Kutzner -- Skin / Tammie Ferringer -- Application of direct immunofluorescence for the skin and mucosal biopsies : a practical review / William B. Tyler -- In situ hybridization in surgical and cytologic specimens / Hong Yin and Barbara Paynton.
  • Origin and fate of hematopoietic precursors in the early mouse embryo / Julien Yuan Bertrand ... [et al.] -- Hematopoietic development in drosophila: a parallel with vertebrates / Marie Meister and Shubha Govind -- Intraembryonic development of hematopoietic stem cells during human ontogeny: expression analysis / Caroline Marshall -- Gene and cell therapy involving hematopoietic stem cell / Isabelle André-Schmutz and Marina Cavazzana-Calvo.Ventral and dorsal contributions to hematopoiesis in xenopus / Aldo Ciau-Uitz, Maggie Walmsley and Roger Patient -- Genetic dissection of hematopoiesis using the zebrafish / Rebecca A. Wingert and Leonard I. Zon -- Extra- and intraembryonic HSC commitment in the avian model / Thierry Jaffredo ... [et al.] -- Avian lymphopoiesis and transcriptional control of hematopoietic stem cell differentiation / Jussi Liippo and Olli Lassila -- Yolk sac development in mice / James Palis -- Long-term reconstituting hematopoietic stem cell capacity in the embryo / Mervin C. Yoder -- The endothelium: the cradle of definitive hematopoiesis? / Katrin Ottersbach and Elaine Dzierzak -- Endothelial and hematopoietic cells in the intraembryonic compartment / Fumio Arai and Toshio Suda --
  • Stem cell biology / Elizabeth O. Hexner and Stephen G. Emerson -- Stem cell transplantation for hematologic malignancies / Effie W. Petersdorf -- Immunobiology of transplantation / Robert S. Negrin -- Allogeneic and autologous hematopoietic stem cell transplantation for acute lymphoblastic leukemia and acute myelogenous leukemia in the adult / Anthony Stein and Stephen J. Forman -- Hematopoietic cell transplantation for chronic myeloid leukemia / Uday Popat and Sergio Giralt -- Stem cell transplantation for Hodgkin's and non-Hodgkin's lymphomas / John W. Sweetenham -- Transplantation in chronic lymphocytic leukemia / Rifca Le Diew and John G. Gribben -- Stem cell transplantation in multiple myeloma / John Koreth and Kenneth C. Anderson -- Allogeneic hematopoietic cell transplantation for patients with myelodysplastic syndrome and myeloproliferative disorders / Aravind Ramakrishnan and H. Joachim Deeg -- Stem cell transplantation for marrow failure / Philippe Armand and Joseph H. Antin -- Stem cell transplantation for hemoglobinopathies / Catherine J. Wu -- Stem cell sources for allogeneic transplantation / Corey Cutler -- Allogeneic unrelated donor blood and marrow transplantation / Daniel Weisdorf -- Umbilical cord hematopoietic stem cell transplantation / Mitchell E. Horwitz and Nelson Chao -- Haploidentical stem cell transplantation / Bimalangshu R. Dey and Thomas R. Spitzer -- Ablative preparative regimens for hematopoietic stem cell transplantation / Amin Alousi and Marcos de Lima -- Nonmyeloablative transplantation / Frédéric Baron and Brenda M. Sandmaier -- Immune reconstitution after allogeneic transplantation / Carolyn A. Keever-Taylor -- Infection in the hematopoietic stem cell transplant recipient / Francisco M. Marty and Lindsey R. Baden -- EBV lymphoproliferative disease after transplantation / Stephen Gottschalk, Cliona M. Rooney, and Helen E. Heslop -- Hepatic veno-occlusive disease / Erica Linden and Paul Richardson -- Lung injury after hematopoietic stem cell transplantation / Kenneth R. Cooke and Gregory Yanik -- Quality of life issues post-transplantation / Stephanie J. Lee -- Pathophysiology of acute graft-versus-host disease / Pavan Reddy and James L.M. Ferrara -- Acute graft-versus-host disease / Martin Benesch and H. Joachim Deeg -- Chronic Graft-versus-host disease / Javier Bolaños-Meade and Georgia B. Vogelsang -- Graft manipulation : T cell depletion and tumor cell purging / Vincent T. Ho -- Donor lymphocyte infusions : clinical applications and the graft-versus-leukemia effect / Edwin P. Alyea -- Regenerative medicine : application in cardiovascular diseases / Emerson C. Perin, Guilherme V. Silva, and Marlos R. Fernandes.
  • Hepatocyte transplantation 2009, Springer Protocols
    Human hepatocyte transplantation overview / Juliana Puppi and Anil Dhawan -- Isolation of human hepatocytes / Ragai R. Mitry -- An optimised method for cryopreservation of human hepatocytes / Claire Terry and Robin D. Hughes -- Liver cell culture techniques / José V. Castell and María José Gómez-Lechón -- In-vitro assays for induction of drug metabolism / Brian G. Lake ... [et al.] -- Hepatocyte apoptosis / Mustapha Najimi, Françoise Smets, and Etienne Sokal -- Small animal models of hepatocyte transplantation / Jurgen Seppen, Ebtisam El Filali, and Ronald Oude Elferink -- Hepatocyte transplantation techniques : large animal models / Anne Weber, Marie Thérèse Groyer-Picard, and Ibrahim Dagher -- Cell transplant techniques : engraftment detection of cells / Robert A. Fisher and Valeria R. Mas -- Hepatic preconditioning for transplanted cell engraftment and proliferation / Yao-Ming Wu and Sanjeev Gupta -- Ex vivo gene transfer into hepatocytes / Xia Wang ... [et al.] -- Sources of adult hepatic stem cells : haematopoietic / Rosemary Jeffery, Richard Poulsom, and Malcolm R. Alison -- Production of hepatocyte-like cells from human amnion / Toshio Miki ... [et al.] -- Generation of hepatocytes from human embryonic stem cells / Niloufar Safinia and Stephen L. Minger -- Isolation, in vitro cultivation, and characterisation of foetal liver cells / Yue Wu, Chetan C. Shatapathy, and Stephen L. Minger -- Human intrahepatic biliary epithelial cell lineages : studies in vitro / Ruth Joplin and Stivelia Kachilele -- Liver cell labelling with MRI contrast agents / Michel Modo, Thomas J. Meade, and Ragai R. Mitry -- Microbiological monitoring of hepatocyte isolation in the GMP laboratory / Sharon C. Lehec.
  • Hepatocytes 2010, Springer Protocols
    1. General review on in vitro hepatocyte models and their applications / Christiane Guguen-Guillouzo and Andre Guillouzo -- 2. Human foetal hepatocytes / Anne Weber ... [et al.] -- 3. Isolation and culture of primary hepatocytes from resected human liver tissue / Edward L. LeCluyse and Eliane Alexandre -- 4. Optimisation of the cryopreservation of primary hepatocytes / Nicola J. Hewitt -- 5. Cryopreservation of human hepatocytes for clinical use / Ragai R. Mitry, Sharon C. Lehec, and Robin D. Hughes -- 6. Hepatocyte differentiation / Katy M. Olsavsky Goyak, Elizabeth M. Laurenzana, and Curtis J. Omiecinski -- 7. Reversible manipulation of apoptosis sensitivity in cultured hepatocytes by matrix-mediated manipulation of signaling activities / Patricio Godoy ... [et al.] -- 8. Markers and signaling factors for stem cell differentiation to hepatocytes / Frédéric Lemaigre -- 9. Hepatic stem cells / Robert E. Schwartz and Catherine Verfaillie -- 10. Hepatic stem cells and liver development / Nalu Navarro-Alvarez, Alejandro Soto-Gutierrez, and Naoya Kobayashi -- 11. Generation of hepatocytes from human embryonic stem cells / Neta Lavon -- 12. Isolation and culture of adult human liver progenitor cells / Sabine Gerbal-Chaloin ... [et al.] -- 13. The HepaRG cell line / Marie-Jeanne Marion, Olivier Hantz, and David Durantel -- 14. Transdifferentiation of pancreatic cells to hepatocytes / Chia-Ning Shen and David Tosh -- 15. Evaluation of drug metabolism, drug-drug interactions and in vitro hepatotoxicity with cryopreserved human hepatocytes / Albert P. Li -- 16. The use of human hepatocytes to investigate drug metabolism and CYP enzyme induction / Sylvie Klieber ... [et al.] -- 17. The use of hepatocytes to investigate UDP-glucuronosyltransferases and sulfotransferases / Sylvie Fournel-Gigleux ... [et al.] -- 18. The use of hepatocytes to investigate drug uptake transporters / Kazuya Maeda and Yuichi Sugiyama -- 19. Metabonomic studies on human hepatocyte in primary culture / Vincent Croizmarie ... [et al.] -- 20. The application of HepRG cells in evaluation of cytochrome P450 induction properties of drug compounds / Tommy B. Andersson -- 21. The use of hepatocytes to investigate drug toxicity / María José Gómez-Lechón, José V. Castell, Maria Teresa Donato -- 22. The use of human hepatocytes to investigate bile acid synthesis / Ewa C.S. Ellis and Lisa-Mari Nilsson -- 23. The use of human hepatocytes to investigate blood coagulation factor / Christine Biron-Andréani ... [et al.] -- 24. Use of human hepatocytes to investigate HCV infection / Lydiane Pichard-Garcia ... [et al.] -- 25. The use of hepatocytes to investigate HDV infection / Camille Sureau -- 26. Rodent models of liver repopulation / Helène Gilgenkrantz -- 27. Chimeric mice with humanized liver / Stephen C. Strom, Julio Davila, and Markus Grompe -- 28. Bioartificial liver support systems / Gesine Pless -- 29. Human hepatocyte transplantation / Anil Dhawan ... [et al.].
  • High content screening 2006, Springer Protocols
  • This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics; and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers.
  • The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorgenesis. This volume presents virtually all aspects of tumor biology because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Rho, Wnt, TGFbeta and p53. Hippo signaling is not solely involved in regulating "classic" tumor characteristics such as cell proliferation, survival and growth, but is also diversely involved in cell-autonomous and non-cell-autonomous differentiation, migration and organ size control. With the multitude of signaling events mediated by the Hippo pathway and the vastly different functions that it plays, it is evident that these tumor suppressors are unique governors of cellular homeostasis. This timely volume gathers wide-ranging and burgeoning information on the Hippo pathway and its role in cancer into an accessible format of a single book.With the multitude of signaling events mediated by the Hippo pathway and the vastly different functions that it plays, it is evident that these tumor suppressors are unique governors of cellular homeostasis. This timely volume gathers wide-ranging and burgeoning information on the Hippo pathway and its role in cancer into an accessible format of a single book.
  • Section 1. Histological and histochemical methods with light microscopy -- section 2. Cytological methods in electron microscopy -- section 3. Image quantification.
  • Histology & cell biology. 5th ed. 2010, AccessMedicine
    Pt 1. Fundamental concepts -- pt 2. The four basic tissue types -- pt 3. Organs and organ systems .
  • Preface -- Host restriction of HIV-1 by APOBEC3 and viral evasion through Vif -- Interactions of viral protein U (Vpu) with cellular factors -- TRIM5alpha -- Human immunodeficiency virus type-1 Gag and host vesicular trafficking pathways -- The roles of tetraspanins in HIV-1 replication -- Imaging of HIV/host protein interactions -- Virological and cellular roles of the transcriptional coactivator LEDGF/p75 -- Implications of Nef: host cell interactions in viral persistence and progression to AIDS -- Vpr and its interactions with cellular proteins.
  • Human adult stem cells 2009, Springer
    1. Neural progenitors / Dustin R. Wakeman ... [et al.] -- 2. Multipotent stromal cells (hMSCs) / Margaret Wolfe ... [et al.] -- 3. Endothelium / Sangmo Kwon, Takayuki Asahara -- 4. Lung / Rabindra Tirouvanziam, Megha Makam, Bruno Péault -- 5. Eye / Maria Notara ... [et al.] -- 6. Colon / F. Iovino ... [et al.] -- 7. Spermatogonia / Makoto C. Nagano, Jonathan R. Yeh, Khaled Zohni -- 8. Hair follicle pluripotent stem (hfPS) cells / Robert M. Hoffman -- 9. Pancreas / Fang-Xu Jiang, Grant Morahan -- 10. Prostate / C. Foley ... [et al.].
  • Human cell culture protocols. 2nd ed. 2005, Springer Protocols
    Establishment and maintenance of normal human keratinocyte cultures / Claire Linge -- Cultivation of normal human epidermal melanocytes in the absence of phorbol esters / Mei-Yu Hsu, Ling Li, and Meenhard Herlyn -- Isolation and culture of human osteoblasts / Alison Gartland ... [et al.] -- Human osteoclast culture from peripheral blood monocytes : phenotypic characterization and quantitation of resorption / Katherine A. Buckley ... [et al.] -- Human chondrocyte cultures as models of cartilage-specific gene regulation / Mary B. Goldring -- Human myoblasts and muscle-derived SP cells / Grace K. Pavlath and Emanuela Gussoni -- Cell cultures of autopsy-derived fibroblasts / Volker Meske, Frank Albert, and Thomas G. Ohm -- Primary culture and differentiation of human adipocyte precursor cells / Vanessa van Harmelen, Thomas Skurk, and Hans Hauner -- Human mononuclear phagocytes in tissue culture / Yona Keisari -- Purification of peripheral blood natural killer cells / Bice Perussia and Matthew J. Loza -- Human fetal brain cell culture / Mark P. Mattson -- Culturing human schwann cells / Victor J. Turnbull --Well-differentiated human airway epithelial cell cultures / M. Leslie Fulcher ... [et al.] -- Isolation and culture of human alveolar epithelial cells / Carsten Ehrhardt, Kwang-Jin Kim, and Claus-Michael Lehr -- A new approach to primary culture of human gastric epithelium / Pierre Chailler and Daniel Ménard -- Isolation and culture of human colon epithelial cells using a modified explant technique employing a noninjurious approach / Hamid A. Mohammadpour -- Isolation and culture of human hepatocytes / Martin Bayliss and Graham Somers -- Glomerular epithelial and mesangial cell culture and characterization / Heather M. Wilson and Keith N. Stewart -- Isolation and culture of human renal cortical cells with characteristics of proximal tubules / Gabrielle M. Hawksworth -- Culture of parathyroid cells / Per Hellman -- Long-term culture and maintenance of human islets of langerhans in Memphis serum-free media / Daniel W. Fraga, A. Osama Gaber, and Malak Kotb -- Primary culture of human antral endocrine and epithelial cells / Susan B. Curtis and Alison M. J. Buchan -- Conjunctiva organ and cell culture / Monica Berry and Marcus Radburn-Smith -- Establishment and maintenance of in vitro cultures of human retinal pigment epithelium / Martin J. Stevens.
  • Pt. 1. Multistep models -- pt. 2. Prostate cancer/stem cells -- pt. 3. Breast cancer/stem cells -- pt. 4. Multistep/genes.
  • Human embryonic stem cell protocols 2006, Springer Protocols
    Human embryonic stem cells: isolation, maintenance and differentiation / Kursad Turksen and Tammy-Claire Troy -- Blastocyst culture for deriving human embryonic stem cells / Ariff Bongso -- Propagation of human embryonic stem cells on human feeder cells / Mark Richards and Ariff Bongso -- Derivation and maintenance of human embryonic stem cells / Michal Amit and Joseph Itskovitz-Eldor -- Isolation and characterization of human embryonic stem cells / Maisam Mitalipova and Gail Palmarini -- Routine culture and differentiation of human embryonic stem cells / Jim McWhir, Davina Wojtacha, and Alison Thomson -- Culture of human embryonic stem cells on human and mouse feeder cells / Gautam Dravid, Holly Hammond, and Linzhao Cheng -- Maintenance of human embryonic stem cells in animal serum- and feeder layer- free culture conditions / Michal Amit and Joseph Itskovitz-Eldor -- Manipulation of self-renewal in human embryonic stem cells through a novel pharmacological GSK-3 inhibitor / Noboru Sato and Ali H. Brivanlou -- Derivation of human feeders for prolonged support of human embryonic stem cells / Chui-Yee Fong and Ariff Bongso -- Transplantation of human embryonic stem cells to the chick embryo / Ronald S. Goldstein -- Derivation and characterization of neuronal precursors and dopaminergic neurons from human embryonic stem cells in vitro / Melissa Carpenter ... [et al.] -- In vitro differentiation of neural precursors from human embryonic stem cells / Xue-Jun Li and Su-Chun Zhang -- Derivation and characterization of hematopoietic cells from human embryonic stem cells / Lisheng Wang ... [et al.] -- Retroviral transduction of hematopoietic progenitors derived from human embryonic stem cells / Pablo Menendez ... [et al.] -- Genetic manipulation of human embryonic stem cells by transfection / Rachel Eiges -- Designing, testing, and validating a microarray for stem cell characterization / Yongquan Luo ... [et al.] -- Microarray approach to identify the signaling network responsible for self-renewal of human embryonic stem cells / Noboru Sato and Ali H. Brivanlou -- Massively parallel signature sequencing / Daixing Zhou ... [et al.] -- Confrontation cultures of embryonic stem cells with multicellular tumor spheroids to study tumor-induced angiogenesis / Maria Wartenberg ... [et al.] -- A novel experimental platform for investigating cancer growth and anti-cancer therapy in a human tissue microenvironment derived from human embryonic stem cells / Maty Tzukerman and Karl L. Skorecki -- The analysis of mitochondria and mitochondrial DNA in human embryonic stem cells / Justin C. St. John ... [et al.].
  • Human stem cell manual. 2nd ed. 2012, ScienceDirect
  • Association between cancer and "acid mucopolysaccharides" : an old concept comes of age, finally -- Hyaluronan-CD44 interactions and chemoresistance in cancer cells -- Growth factor regulation of hyaluronan deposition in malignancies -- Hyaluronan binding protein 1 (HABP1/p32/gClqR) : a new perspective in tumor development -- CD44 meets Merlin and Ezrin : their interplay mediates the pro-tumor activity of CD44 and tumor-suppressing effect of Merlin -- Hyaluronan-mediated CD44 interaction with receptor and non-receptor kinases promotes oncogenic signaling, cytoskeleton activation, and tumor progression -- Adhesion and penetration : two sides of CD44 signal transduction cascades in the context of cancer cell metastasis -- Involvement of CD44, a molecule with a thousand faces, in cancer dissemination -- RHAMM/HMMR : an itinerant and multifunctional hyaluronan binding protein that modifies CD44 signaling and mitotic spindle formation -- Altered hyaluronan biosynthesis in cancer progression --Hyaluronidase : both a tumor promoter and suppressor -- The hyaluronidases in cancer biology -- Hyaluronan fragments : informational polymers commandeered by cancers -- Hyaluronan in human tumors : importance of stromal and cancer cell-associated hyaluronan -- The oncofetal paradigm revisited : MSF and HA as contextual drivers of cancer progression -- Hyaluronan synthesis and turnover in prostate cancer -- Role of hyaluronan in melanoma progression -- Role of hyaluronan metabolism in the initiation, invasion, and metastasis of breast cancer -- Clinical use of hyaluronidase in combination cancer chemotherapy : a historic perspective -- Exploring the hyaluronan:CD44 interaction for cancer therapy -- Hyaluronidase-2 and its role as a cell-entry receptor for sheep retroviruses that cause contagious respiratory tract cancers.
  • Pt. B ScienceDirect
    Pt. C ScienceDirect
  • The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition "Th17 Cells: Role in Inflammation and Autoimmune Disease" in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naïve T cells into regulatory T cells and Th17 cells as well as the plasticity of Th17 cells is discussed.
  • Recent years have witnessed numerous advances in stem cell research that have suggested novel strategies for the treatment of the chronic and regenerative diseases that pose a growing challenge to the provision of healthcare in the 21<sup>st</sup> century. Nevertheless, there is little doubt that related disciplines have failed to keep pace with such developments, of which the immunology of transplant rejection is perhaps the most relevant to the nascent field of regenerative medicine. Indeed, given that after decades of research into the mechanisms of organ allograft rejection, we remain wholly dependent on immune suppression to ensure acceptance of foreign tissues, we might legitimately ask whether there is any reason why tissues differentiated from stem cells might not suffer the same fate. This volume seeks to address this issue by drawing on the principles of alloantigen recognition to assess the validity of early convictions that embryonic stem cell-derived tissues may prove invisible to the immune system of the host and the more recent belief that induced pluripotent stem cells, derived in a fully autologous manner, will circumvent the issue of immunogenicity. Having debunked such assumptions and established the magnitude of the immunological barriers to be overcome, this book then draws on the expertise of internationally-recognised laboratories around the world to provide a critical assessment of the likely success of applying strategies such as stem cell banking, silencing of genes that confer immunogenicity, and the induction of transplantation tolerance to overcoming the immunological barriers in the future. Indeed, it is only through reaching a consensus in the field that enduring solutions to such an intractable problem may ultimately emerge.
  • Intracellular delivery : 2011, Springer
  • Invasive cytopathologist 2014, Springer
  • Jak-Stat signaling 2012, Springer
    The Continuing Fascination with Jaks and Stats: An Introduction /Thomas Decker and Mathias Müller --Regulation of JAKs: Insights Gleaned from the Functional Protein Domains /Claude Haan, Daniela Ungureanu, Tuija Pekkala, Olli Silvennoinen and Serge Haan --Nuclear Functions of the Janus Kinases /Mark A. Dawson and Andrew J. Bannister --Self-association of STAT Proteins from Monomers to Paracrystals /Mathias Droescher and Uwe Vinkemeier --How Stats Interact with the Molecular Machinery of Transcriptional Activation /Amanda M. Jamieson, Matthias Farlik and Thomas Decker --Nongenomic Functions of STAT3 /Daniel J. Gough, Pravin Sehgal and David E. Levy --Evolution of Jak and Stat Proteins /Claus Vogl, Priyank Shukla and Ingo Ebersberger --JAK/STAT and Chromatin Regulation in Drosophila /Kriti Gaur and Willis X. Li --JAK/STAT Signaling and Invertebrate Immune Responses /Feng Zhou and Hervé Agaisse --Stat5 as a Hematopoietic Master Regulator for Differentiation and Neoplasia Development /Harini Nivarthi, Katrin Friedbichler and Richard Moriggl --Regulation of Dendritic Cell Development by STATs /Haiyan S. Li and Stephanie S. Watowich.STAT Transcription Factors: Controlling All Aspects of NK Cell Biology /Eva Maria Putz, Eva Zebedin and Veronika Sexl --Function of JAKs and STATs in Lymphocytes: Bench to Bedside /Alejandro Villarino, Xiang-Ping Yang, Kiyoshi Hirahara, Yuka Kanno and John J. O' Shea, et al. --The Role of Janus Kinases in Hematopoietic Malignancies /Damla Olcaydu and Robert Kralovics --Activation of Janus Kinases During Tumorigenesis /Jeffrey W. Schmidt and Kay-Uwe Wagner --STAT1 and STAT3 Transcription Factors in Inflammation-associated Colon Cancer /Paulina Rampetsreiter and Robert Eferl --Universal and Specific Functions of STAT3 in Solid Tumours /Lidia Avalle, Gabriella Regis and Valeria Poli --Impact of STAT5 on Normal Tissue Development and Cancer /Maria M. Caffarel and Christine J. Watson --Crosstalk with the Jak-STAT Pathway in Inflammation /Lionel B. Ivashkiv --Activation and Inhibition of JAK-STAT Signal Transduction by RNA Viruses /Curt M. Horvath --Multifaceted Antiviral Actions of Interferon-stimulated Gene Products /Birgit Strobl, Nicole R. Leitner and Mathias Müller --Interferon Regulation of the Innate Response to Bacteria /Ali Abdul-Sater and Christian Schindler.
  • Kinetochore 2009, Springer
    Centromeres and kinetochores : an historical perspective /Kerry S. Bloom --The basics of chromosome segregation /Mitsuhiro Yanagida --The centromere /Beth A. Sullivan --Neocentromeres /Owen J. Marshall and K.H. Andy Choo --Human artificial centromeres : de novo assembly of functional centromeres on human artificial chromosomes /Hiroshi Masumoto, Teruaki Okada, and Yasuhide Okamoto --Kinetochore composition, formation, and organization /Tatsuo Fukagawa and Peter De Wulf --Evolution of centromeres and kinetochores : a two-part fugue /Paul B. Talbert, Joshua J. Bayes, and Steven Henikoff --Mitotic spindle assembly mechanisms /Rebecca Heald and Claire E. Walczak --Kinetochore-microtubule interactions /Lesley Clayton and Tomoyuki U. Tanaka --Post-translational modifications that regulate kinetochore activity /Chitra V. Kotwaliwale and Sue Biggins --The role of the kinetochore in spindle checkpoint signaling /P. Todd Stukenberg and Daniel J. Burke --Kinetochore regulation of anaphase and cytokinesis /Scott Thomas and Kenneth B. Kaplan --Roles of centromeres and kinetochores in meiosis /Adele L. Marston --The kinetochore-cancer connection /Takeshi Tomonaga --The kinetochore as target for cancer drug development /Song-tao Liu and Tim J. Yen.
  • Structural dynamics of nucleic acids by single-molecule FRET / Asger Christian Krüger, Lasse Lava Hildebrandt, Sofie Louise Kragh, Victoria Birkedal -- Visualizing the location and the dynamics of gene expression in living animals through bioluminescence imaging / Xiaojuan Chen -- Quality control protocol for confocal system / Anda Cornea -- Electron microscopy of bone / V. Everts, K.A. Hoeben -- Immunostaining : detection of signaling protein location in tissues, cells and subcellular compartments / Biswanath Maity, David Sheff, Rory A. Fisher -- Bimolecular fluorescence complementation (BiFC) analysis of protein-protein interaction : how to calculate signal-to-noise ratio / Yutaka Kodama, Chang-Deng Hu -- Immunohistochemical detection of neuropeptides/transmitters in mammalian brain / Lothar Jennes -- Intravital imaging of autoreactive T. cells in living animals / Naoto Kawakami, Ingo Bartholomäus, Marija Pesic, Nikolaos I. Kyratsous -- Genetically encoded click chemistry for single-molecule FRET of proteins / Swati Tyagi, Edward A. Lemke -- High-throughput methods for the detection of protein overexpression using fluorescence markers / Mads Gabrielsen, Andrew J. Roe, Karen McLuskey -- Correlative microscopy / Alexander A. Mironov, Galina V. Beznoussenko -- Stereology of the lung / Jan Philipp Schneider, Matthias Ochs -- Quantitative 3D cell-based assay performed with cellular spheroids and fluorescence microscopy / Nariman Ansari, Stefanie Müller, Ernst H.K. Stelzer, Francesco Pampaloni -- Optimizing fluorescence excitation and detection for intravital two-photon microscopy / Dan Suan, Henry R. Hampton, Michio Tomura, Osami Kanagawa, Tatyana Chtanova, Tri Giang Phan -- Two-dimensional crystallization by dialysis for structural studies of membrane proteins by the cryo-EM method electron crystallography / Matthew C. Johnson, Ingeborg Schmidt-Krey -- In situ hybridization / Chung-Jui Tsai, Scott A. Harding -- RNA imaging : tracking in real-time RNA transport in neurons using molecular beacons and confocal microscopy / Angélica Zepeda, Clorinda Arias, Fabian Flores-Jasso, Luis Vaca.
  • Cell biology spans among the widest diversity of methods in the biological sciences. From physical chemistry to microscopy, cells have given up with secrets only when the questions are asked in the right way! This new volume of Methods in Cell Biology covers laboratory methods in cell biology, and includes methods that are among the most important and elucidating in the discipline, such as transfection, cell enrichment and magnetic batch separation. Covers the most important laboratory methods in cell biology Chapters written by experts in their fields.
  • Light microscopy 2011, Springer Protocols
    Glycol methacrylate embedding for improved morphological, morphometrical, and immunohistochemical investigations under light microscopy : testes as a model /Hélio Chiarini-Garcia, Gleydes Gambogi Parreira, and Fernanda R.C.L. Almeida --Histological processing of teeth and periodontal tissues for light microscopy analysis /Gerluza Aparecida Borges Silva, Adriana Moreira, and José Bento Alves --Large plant samples: how to process for GMA embedding /Élder Antônio Sousa Paiva, Sheila Zambello de Pinho, and Denise Maria Trombert Oliveira --Image cytometry : nuclear and chromosomal DNA quantification /Carlos Roberto Carvalho, Wellington Ronildo Clarindo, and Isabella Santiago Abreu --Histological approaches to study tissue parasitism during the experimental Trypanosoma cruzi infection /Daniela L. Fabrino, Grazielle A. Ribeiro, Livia Teixeira, and Rossana C.N. Melo --Intravital microscopy to study leukocyte recruitment in vivo /Vanessa Pinho ... [et al.] --Introduction to fluorescence microscopy /Ionita C. Ghiran --Using the fluorescent styryl dye FM1-43 to visualize synaptic vesicles exocytosis and endocytosis in motor nerve terminals /Ernani Amaral, Silvia Guatimosim, and Cristina Guatimosim --Imaging lipid bodies within leukocytes with different light microscopy techniques /Rossana C.N. Melo ... [et al.] --Eicosa cell : an immunofluorescent-based assay to localize newly synthesized eicosanoid lipid mediators at intracellular sites /Christianne Bandeira-Melo, Peter F. Weller, and Patricia T. Bozza --Nestin-driven green fluorescent protein as an imaging marker for nascent blood vessels in mouse models of cancer /Robert M. Hoffman --Imaging calcium sparks in cardiac myocytes /Silvia Guatimosim, Cristina Guatimosim, and Long-Sheng Song --Light microscopy in aquatic ecology: methods for plankton communities studies /Maria Carolina S. Soares ... [et al.] --Fluorescence immunohistochemistry in combination with differential interference contrast microscopy for studies of semi-ultrathin specimens of epoxy resin-embedded samples /Shin-ichi Iwasaki and Hidekazu Aoyagi.
  • Lipid droplets 2013, ScienceDirect
    This new volume of Methods in Cell Biology looks at lipid droplets LDs, covering sections on analyses of LDs in model systems, cell/tissue-specific analyses of LDs and imaging and in vitro analyses of LD biogenesis and growth. Chapters are written by experts in the field. With cutting-edge material, this comprehensive collection is intended to guide researchers of LDs for years to come. Covers sections on analyses of lipid droplets (LDs) in model systems, cell/tissue-specific analyses of LDs and imaging, and in vitro analyses of LD biogenesis and growth Chapters are written by experts in t
  • Sphingomyelin and its role in cellular signaling / Mahua Chakraborty and Xian-Cheng Jiang -- The driving force of alpha-synuclein insertion and amyloid channel formation in the plasma membrane of neural cells: key role of ganglioside- and cholesterol-binding domains / Jacques Fantini and Nouara Yahi -- The enigmatic role of sulfatides: new insights into cellular functions and mechanisms of protein recognition / Shuyan Xiao, Carla V. Finkielstein, and Daniel G. S. Capelluto -- Phosphoinositides and PDZ domain scaffolds / Anna Maria Wawrzyniak, Rudra Kashyap and Pascale Zimmermann -- PtdIns(4)P signalling and recognition systems / Marc Lenoir and Michael Overduin -- PtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanism / Arne Gericke, Nicholas R. Leslie, Mathias Lösche, and Alonzo H. Ross -- Role of phosphatidylinositol 3,4,5-trisphosphate in cell signaling / Robert D Riehle, Sinziana Cornea and Alexei Degterev -- The role of phosphoinositides and inositol phosphates in plant cell signaling / Glenda E. Gillaspy -- Phosphatidic acid-mediated signaling / Yu Liu, Yuan Su, and Xuemin Wang -- Phosphatidylserine-mediated cellular signaling / Jason G. Kay and Sergio Grinstein -- Cardiolipin-mediated cellular signaling / Vinay A. Patil and Miriam L. Greenberg.
  • Lipids. 1st ed. 2012, ScienceDirect
    Supported native plasma membranes as platforms for the reconstitution and visualization of endocytic membrane budding / Min Wu, Pietro de Camilli -- Studying lipids involved in the endosomal pathway / Christin Bissig, Shem Johnson, Jean Gruenberg -- Studying in vitro membrane curvature recognition by proteins and its role in vesicular trafficking / Jean-Baptiste Manneville, Cécile Leduc, Benoit Sorre, Guillaume Drin -- Reconstituting multivesicular body biogenesis with purified components / Thomas Wollert -- Approaches to the study of Atg8-mediated membrane dynamics in vitro / Anjai Jotwani, Diana N. Richerson, Isabelle Motta, Omar Julca-Zevallos, Thomas J. Melia -- Reconstitution assay system for ceramide transport with semi-intact cells / Keigo Kumagai, Masahiro Nishijima, Kentaro Hanada -- Visualizing mitochondrial lipids and fusion events in mammalian cells / Huiyan Huang, Michael A. Frohman -- Targeted and non-targeted analysis of membrane lipids using mass spectrometry / Xue Li Guan, Markus R. Wenk -- Modulation of host phosphoinositide metabolism during salmonella invasion by the type III secreted effector SopB / Bernhard Roppenser, Sergio Grinstein, John H. Brumell -- Acute manipulation of phosphoinositide levels in cells / Belle Chang-Ileto, Samual G. Frere, Gilbert Di Paolo -- Regulation of phosphoinositide-metabolizing enzymes by clathrin coat proteins / Marnix Wieffer, Volker Haucke, Michael Krauß -- Phosphoinositides at the neuromuscular junction of drosophila melanogaster : a genetic approach / Jan R. Slabbaert, Thang Manh Khuong, Patrik Verstreken -- Devising powerful genetics, biochemical and structural tools in the functional analysis of phosphatidylinositol transfer proteins (PITPs) across diverse species / James M. Davison, Vytas A. Bankaitis, Ratna Ghosh -- Genome-wide screens for gene products regulating lipid droplet dynamics / Weihua Fei, Hongyuan Yang -- The three dimensionality of cell membranes : lamellar to cubic membrane transition as investigated by electron microsocopy / Ketpin Chong, Yuru Deng -- Quantitative imaging of lipid metabolism in yeast : from 4D analysis to high content screens of mutant libraries / Heimo Wolinski, Kristian Bredies, Sepp D. Kohlwein -- Analysis of cholesterol trafficking with fluorescent probes / Frederick R. Maxfield, Daniel Wüstner -- Fluorescence correlation methods for imaging cellular behavior of sphingolipid-interacting probes / Rachel Kraut, Nirmalya Bag, Thorsten Wohland -- Monitoring phospholipid dynamics during phagocytosis : application of genetically-encoded fluorescent probes / Helen Sarantis, Sergio Grinstein -- Genetically encoded probes for phosopatidic acid / Nawal Kassas, Petra Tryoen-Tóth, Matthias Corrotte, Tamou Thahouly, Marie-France Bader, Nancy J. Grant, Nicolas Vitale.
  • Protein kinase C-theta (PKC[theta]): new perspectives on its functions in T-cell biology / Rina Barouch-Bentov and Amnon Altman -- Travel informations on the tec kinases during lymphocyte activation / Fabien Garçon and Jacques A. Nunès -- Inducible T-cell tyrosine kinase (ITK): structural requirements and actin polymerization / Constantine D. Tsoukas ... [et al.] -- Differential requirements of PI3K subunits for BCR or BCR/CD19-induced ERK activation / Elena Vigorito and Martin Turner -- Protein tyrosine phosphatases in human disease / Tomas Mustelin -- The T-cell-specific adapter protein functions as a regulator of peripheral but not central immunological tolerance / Philip E. Lapinski ... [et al.] -- Proximal signals controlling B-cell antigen receptor (BCR) mediated NF-[kappa]B activation / Miguel E. Moreno-García ... [et al.] -- The adapter 3BP2: how it plugs into leukocyte signaling / Marcel Deckert and Robert Rottapel -- CTLA-4 regulation of T-cell function via RAP-1-mediated adhesion / Helga Schneider ... [et al.] -- Protein crosstalk in lipid rafts / Raquel J. Nunes, Mónica A.A. Castro, and Alexandre M. Carmo -- Role of lipid rafts in activation-induced cell death: the fas pathway in aging / Anis Larbi ... [et al.] -- T-cell response in aging: influence of cellular cholesterol modulation / Tamàs Fülöp ... [et al.] -- Lymphocyte signaling and the translatability of mRNA / Suzanne Miyamoto -- Protein arginine methylation: a new frontier in T-cell signal transduction / Brandon T. Schurter, Fabien Blanchet, and Oreste Acuto -- Immune regulation by ubiquitin conjugation / K. Venuprasad ... [et al.] -- CTIB (C-terminus protein of I[kappa]B-[beta]): a novel factor required for acidic adaptation /Toshiko Fukamachi ... [et al.] -- HIV may deplete most CD4 lymphocytes by a mechanism involving signaling through its receptors on non-permissive resting lymphocytes / Miles W. Cloyd ... [et al.] -- Integrating traditional and postgenomic approaches to investigate lymphocyte development and function / Yina Hsing Huang ... [et al.] -- Phosphoproteomic analysis of lymphocyte signaling / Lulu Cao, Kebing Yu, and Arthur R. Salomon.
  • Lysosomes 2005, Springer
    History and morphology of the lysosome / Renate Lüllmann-Rauch -- Transport of lysosomal enzymes / Stephan Storch and Thomas Braulke -- Adaptor proteins in lysosomal biogenesis / Peter Schu -- Lysosomal membrane proteins / Paul Saftig -- Lysosomal proteases: revival of the sleeping beauty / Klaudia Brix -- Lysosomal storage disorders / Ole Kristian Greiner-Tollersrud and Thomas Berg -- Lysosomal transporters and associated diseases / Frans W. Verheijen and Grazia M.S. Mancini -- Neuronal ceroid-lipofuscinoses / Jaana Tyynelè -- Cholesterol transport in lysosomes / Judith Storch and Sunita R. Cheruku -- Therapy of lysosomal storage diseases / Ulrich Matzner -- Lysosomal proteome and transcriptome / Jobst Landgrebe and Torben Lubke -- External lysosomes: the osteoclast and its unique capacities / Vincent Everts and Wouter Beertsen -- Membrane resealing mediated by lysosomal exocytosis / Norma W. Andrews -- Macroautophagy in mammalian cells / Eeva-Liisa Eskelinen -- Chaperone-mediated autophagy / Erwin Knecht and Natalia Salvador.
  • Introduction -- Molecular machines -- The processes of living -- Molecules in cells: Escherichia coli -- A human cell: The advantages of compartments -- The human body: The advantages of specialization -- Life and death -- Viruses -- You and your molecules.
  • Macrophages and dendritic cells 2009, Springer Protocols
    Generation of retroviral macrophage cDNA expression libraries and functional screening for surface receptors / Georgia Schäfer and Gordon D. Brown -- Generation of murine growth factor-dependent long-term dendritic cell lines to investigate host-parasite interactions / Alessandra Mortellaro ... [et al.] -- Macrophage activation : classical vs. alternative / Andrea Classen, Jorge Lloberas, and Antonio Celada -- Analysis of macrophage phagocytosis : quantitative assays of phagosome formation and maturation using high-throughput florescence microscopy / Benjamin E. Steinberg and Sergio Grinstein -- Detection of activated Rab7 GTPase with an immobilized RILP probe / Jim Sun ... [et al.] -- Probing in vivo origins of mononuclear phagocytes by conditional ablation and reconstitution / Chen Varol, Limor Landsman, and Steffen Jung -- Multivalent protein probes for the identification and characterization of cognate cellular ligands for myeloid cell surface receptors / Hsi-Hsien Lin ... [et al.] -- Exploiting Fc chimaeric proteins for the identification of ligands specific for the mannose receptor / Luisa Martinez-Pomares -- The expression of exogenous genes in macrophages : obstacles and opportunities / Xia Zhang, Justin P. Edwards, and David M. Mosser -- Genetic modification of murine dendritic cells by RNA transfection / Maurizio Ceppi, Enrico Schmidt, and Philippe Pierre -- Recording phagosome maturation through the real-time, spectrofluorometric measurement of hydrolytic activities / Robin M. Yates, Albin Hermetter, and David G. Russell -- Derivation and characterization of murine alternatively activated (M2) macrophages / Victor W.H. Ho and Laura M. Sly -- Isolation and culture of human hematopoietic progenitors for studies of dendritic cell biology / Mattias Svensson -- Generation, culture, and flow-cytometric characterization of primary mouse macrophages / Ulrike Schleicher and Christian Bogdan -- Analyzing classical and alternative macrophage activation in macrophage/neutrophil-specific IL-4 receptor-alpha-deficient mice / Frank Brombacher ... [et al.] -- Analysis of matrix metalloproteinase secretion by macrophages / Paul T. Elkington, Justin A. Green, and Jon S. Friedland -- Identification of pathogen receptors on dendritic cells to understand their function and to identify new drug targets / Lot de Witte ... [et al.] -- Stable lentiviral vector-mediated gene silencing in human monocytic cell lines / Jimmy S. Lee and Neil E. Reiner -- Use of fluorescent probes to detect lipid signaling intermediates in macrophages / Vivan Kwok, Eric Vachon, and Gregory P. Downey -- Large-scale phagosome preparation / Adrien F. Vinet and Albert Descoteaux -- Coordinate regulation of sphingosine kinase and actin dynamics / Shankar S. Iyer and David J. Kusner.
  • Male germline stem cells 2011, Springer
  • Mast cell biology 2011, Springer
    Mast cell biology : introduction and overview / Alasdair M. Gilfillan, Sarah J. Austin, and Dean D. Metcalfe -- Mast cell progenitor trafficking and maturation / Jenny Hallgren and Michael F. Gurish -- Monomeric IgE and mast cell development, survival, and function / Jun-ichi Kashiwakura, Iris M. Otani, and Toshiaki Kawakami -- Mast cell apoptosis and survival / Maria Ekoff and Gunnar Nilsson -- Regulators of Ca2+ signaling in mast cells: Potential targets for treatment of mast cell-related diseases / Hong-Tao Ma and Michael A. Beaven -- Spatio-temporal signaling in mast cells / Bridget S. Wilson, Janet M. Oliver, and Diane S. Lidke -- The mechanisms of exocytosis in mast cells / Ulrich Blank -- An emerging role for the lipid mediator sphingosine-1-phosphate in mast cell effector function and allergic disease / Ana Olivera and Juan Rivera -- Down-regulation of mast cell responses through itim containing inhibitory receptors / Laila Karra and Francesca Levi-Schaffer -- The mast cell in innate and adaptive immunity / Christopher P. Shelburne and Soman N. Abraham -- Mast cells and immunoregulation/immunomodulation / Mindy Tsai, Michele Grimbaldeston, and Stephen J. Galli -- Mast cell proteases as protective and inflammatory mediators / George H. Caughey -- Mast cells in lung inflammation / Elena P. Moiseeva and Peter Bradding -- Mast cells, angiogenesis, and cancer / Domenico Ribatti and Enrico Crivellato.
  • Mast cells 2005, Springer Protocols
    Paul Ehrlich's "Mastzellen"--from aniline dyes to DNA chip arrays : a historical review of developments in mast cell research / Harsha Vyas and Guha Krishnaswamy -- The human mast cell : an overview / Guha Krishnaswamy, Omar Ajitawi, and David S. Chi -- Mast cells in allergy and autoimmunity : implications for adaptive immunity / Gregory D. Gregory and Melissa A. Brown -- Analysis of MCT and MCTC mast cells in tissue / Lawrence B. Schwartz -- Mast cell ultrastructure and staining in tissue / Shruti A. Shukla ... [et al.] -- Expression of cell surface antigens on mast cells : mast cell phenotyping / Alexander W. Hauswirth ... [et al.] -- Identification of mast cells in the cellular response to myocardial infarction / Nikolaos G. Frangogiannis and Mark L. Entman --Growth of human mast cells from bone marrow and peripheral blood-derived CD34+ pluripotent progenitor cells / Arnold S. Kirshenbaum and Dean D. Metcalfe -- Culture of human mast cells from hemopoietic progenitors / Hirohisa Saito -- Isolation, culture, and characterization of intestinal mast cells / Gernot Sellge and Stephan C. Bischoff -- Activation of nuclear factor kappa B / Chuanfu Li, Jim Kelley, and Tuanzhu Ha -- Analysis of mitogen-activated protein kinase activation / Stephen C. Armstrong -- Microarray and gene clustering analysis / Tsung-Hsien Tsai, Denise M. Milhorn, and Shau-Ku Huang -- Techniques to study Fc [epsilon] RI signaling / Yuko Kawakami, Jiro Kitaura, and Toshiaki Kawakami -- Human mast cell proteases : activity assays using thiobenzyl ester substrates / David A. Johnson --Mast cell histamine and cytokine assays / David S. Chi, S. Matthew Fitzgerald, and Guha Krishnaswamy -- Measurement of mast cell cytokine release by multiplex assay / Kevin F. Breuel and W. Keith De Ponti -- Assays for histamine-releasing factors : from identification and cloning to discovery of binding partners / Jacqueline M. Langdon and Susan M. McDonald -- Assays for nitric oxide expression / William L. Stone, Hongsong Yang, and Min Qui -- Immunohistological detection of growth factors and cytokines in tissue mast cells / Zhenhong Qu -- Endothelial cell activation by mast cell mediators / Kottarappat N. Dileepan and Daniel J. Stechschulte -- Co-culture of mast cells with fibroblasts : a tool to study their crosstalk / Ido Bachelet, Ariel Munitz, and Francesca Levi-Schaffer --Detection of E class switching and IgE synthesis in human B cells / Jérôme Péne ... [et al.] -- Gene silencing using small interference RNA in mast cells / Deling Yin and Charles A. Stuart -- Mast cell activation by lipoproteins / Jim Kelley ... [et al.] -- Mast cell activation by stress / Ann L. Baldwin -- In vivo models for studying mast cell-dependent responses to bacterial infection / Christopher P. Shelburne, James B. McLachlan, and Soman N. Abraham -- Bacterial activation of mast cells / David S. Chi ... [et al.] -- Activation of mast cells by streptolysin O and lipopolysaccharide / Michael Stassen ... [et al.] -- Mast cell apoptosis / Alexander Gerbaulet, Karin Hartmann, and Yoseph A. Mekori.
  • Mast cells and tumours 2011, Springer
  • The volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. In our opinion the book presents not only the latest achievements in the field but also brings the problem closer to the experts in related medical and biological sciences as well as practicing doctors. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different living organs and tissues and allows to predict changes, which arise due to alterations of their environment, and possibly will allow to develop new methods of artificial intervention. We also hope that presenting the problem will attract more attention to it both from researchers and practitioners and will assist to efficiently introduce it into the practical medicine.
  • Mechanosensitivity of cells from various tissues -- Mechanotransduction in the Nematode Caenorhabditis elegans -- Mechanically mediated crosstalk in heart -- Swelling-and stretch-activated chloride channels in the heart: regulation and function -- Role of stretch-activated channels in the heart: action potential and Ca2+ transients -- Isolated cardiomyocytes: mechanosensitivity of action potential, membrane current and ion concentration -- Mechano-electric feedback in the heart: evidence from intracellular microelectrode recordings on multicellular preparations and single cells from healthy and diseased tissue -- The Role of mechanosensitive fibroblasts in the heart -- Mechanical modulation of intracellular ion concentrations: mechanisms and electrical consequences -- Stretch-induced slow force response in mammalian ventricular myocardium -- The Na+/H+ exchanger as the main protagonist following myocardial stretch: the Anrep effect and myocardial hypertrophy -- Mechano-electric feedback and atrial arrhythmias -- The Role of mechano-electrical feedback in the cholinergic atrial fibrillation initiation --; Mechanosensitive cation channels of leech neurons -- Mechanosensitivity of primary afferent nociceptors in the pain pathway -- Stimulus-secretion coupling in the osmoreceptive prolactin cell of the tilapia -- Stretch-inactivated channels in skeletal muscle -- Stretch-activated cation channels and the myogenic response of small arteries -- Mechanobiology of bone tissue and bone cells -- Functional roles of mechanosensitive ion channels, ss1 integrins and kinase cascades in chondrocyte mechanotransduction -- Enigmatic roles of the epithelial sodium channel (ENaC) in articular chondrocytes and osteoblasts: mechanotransduction, sodium transport or extracellular sodium sensing?
  • From intramolecular asymmetries to raft assemblies: a short guide for the puzzled in lipidomics / Ephraim Yavin and Annette Brand -- Regulatory aspects of membrane microdomain (raft) dynamics in live cells: a biophysical approach / János Matkó and János Szöllosi -- Lipid raft membrane skeletons / Elizabeth J. Luna ... [et al.] -- Role of cholesterol in membrane microdomain signaling / Christopher J. Fielding -- Raft lipid metabolism in relation to alkyl-lysophospholipid-induced apoptosis / Arnold H. van der Luit, Marcel Verheij, and Wim J. van Blitterswijk -- Role of lipid rafts in signal transduction and synaptic plasticity of neural cells / Markus Delling and Melitta Schachner -- Role of rafts in virus fusion and budding / Wu Ou and Jonathan Silver -- Alterations in raft lipid metabolism in aging and neurodegenerative disorders / Mark P. Mattson, Roy G. Cutler, and Norman J. Haughey -- Caveolin and cancer: a complex relationship / Mordechai Liscovitch ... [et al.] -- Dietary modulation of lipid rafts: implications for disease prevention and treatment / Mark P. Mattson.
  • Membrane trafficking 2008, Springer Protocols
    Pt. I. Yeast Cells -- Ch. 1. Freight management in the cell / Johannes M. Herrmann, Anne Spang -- Ch. 2. High-throughput protein extraction and immunoblotting analysis in saccharomyces cerevisiae / Todd C. Lorenz, Vikram C. Anand, Gregory S. Payne -- Ch. 3. Genome-wide analysis of membrane transport using yeast knockout arrays / Helen E. Burston, Michael Davey, Elizabeth Conibear -- Ch. 4. A cell-free system for reconstitution of transport between prevacuolar compartments and vacuoles in saccharomyces cerevisiae / Thomas A. Vida -- Ch. 5. In vitro analysis of the mitochondrial preprotein import machinery using recombinant precursor polypeptides / Dorothea Becker, Martin Krayl, Wolfgang Voos -- Ch. 6. In vitro import of proteins into isolated mitochondria / Karl Bihlmaier, Melanie Bien, Johannes M. Herrmann -- Ch. 7. Synthesis and sorting of mitochondrial translation products / Heike Bauerschmitt, Soledad Funes, Johannes M. Herrmann -- Ch. 8. In vivo labeling and analysis of mitochondrial translation products in budding and in fission yeasts / Karine Gouget, Fulvia Verde, Antoni Barrientos --Ch. 9. Exploring protein-protein interactions involving newly synthesized mitochondrial DNA encoded proteins / Darryl Horn, Flavia Fontanesi, Antoni Barrientos -- Ch. 10. Purification of yeast membranes and organelles by sucrose density gradient centrifugation / Jennifer Chang, Victoria Ruiz, Ales Vancura -- Ch. 11. Microscopic analysis of lipid droplet metabolism and dynamics in yeast / Heimo Wolinski, Sepp D. Kohlwein -- Ch. 12. Use of bimolecular fluorescence complementation (BiFC) in yeast saccharomyces cerevisiae / Kari-Pekka Skarp, ... [et al.] -- Pt. II. Mammalian cells -- Ch. 13. Using quantitative fluorescence microscopy to probe organelle assembly and membrane trafficking / Brian Storrie, Tregei Starr, Kimberly Forsten-Williams -- Ch. 14. Measuring secretory membrane traffic / Vytaute Starkuviene, ... [et al.] -- Ch. 15. A correlative light and electron microscopy method based on laser micropatterning and etching / Julien Colombelli, ... [et al.] -- Ch. 16. Approaches to investigate the role of signaling in ER-to-Golgi transport / Laura J. Sharpe, Ximing Du, Andrew J. Brown -- Ch. 17. Recruitment of coat proteins to peptidoliposomes / Gregor Suri, Martin Spiess, Pascal Crottet --Ch. 18. SNAREs mediated fusion of liposomes / Jérôme Vicogne, Jeffrey E. Pessin -- Ch. 19. Use of polarized PC12 cells to monitor protein localization in the early biosynthetic pathway / Ragna Sannerud, ... [et al.] -- Ch. 20. Tracking the transport of E-cadherin to and from the plasma membrane / Matthew P. Wagoner, Kun Ling, Richard A. Anderson -- Ch. 21. Analysis of nucleocytoplasmic shuttling of NFkB proteins in human leukocytes / Chandra C. Ghosh ... [et al.] -- Ch. 22. Imaging pHluorin-based probes at hippocampal synapses / Stephen J. Royle, ... [et al.] -- Ch. 23. Analysis of receptor tyrosine kinase internalization using flow cytometry / Ning Li, Kristen S. Hill, Lisa A. Elferink -- Ch. 24. Measurement of receptor endocytosis and recycling / Jane M. Knisely, Jiyeon Lee, Guojun Bu -- Ch. 25. Styryl dye-based synaptic vesicle recycling assay in cultured cerebellar granule neurons / Victor Anggono, Michael A. Cousin, Phillip J. Robinson -- Ch. 26. Use of quantitative immunofluorescence microscopy to study intracellular trafficking / Vincent Blot, Timothy E. McGraw -- Ch. 27. Dissecting GLUT4 traffic components in L6 myocytes by fluorescence-based, single cell assays / Costin N. Antonescu, Varinder K Randhawa, Amira Klip -- Ch. 28. Functional genetic analysis of the mammalian mitochondrial DNA encoded peptides / Maria Pilar Bayona-Bafaluy, ... [et al.].
  • Mesenchymal Stem Cells or Multipotent Mesenchymal Stromal Cells (collectively referred to as MSCs) are currently being tested in a number of clinical trials for various diseases including graft-versus-host disease, Crohn's disease, myocardial infarction, stroke, diabetes, cartilage defects, and many others. The increasing number of clinical trials globally indicates the likely therapeutic potential of this specialized adult stem cell. Over the last decade, there has been tremendous progress towards understanding an MSC's phenotype, expansion features in culture, differentiation ability and global gene and protein expression profiles. Despite the enormous progress and data accrual at the molecular and cellular levels, several questions remain as to the utility of MSCs for clinical applications. Mesenchymal Stem Cell Therapy is a comprehensive collection of information comprised of both basic and pre-clinical biological studies as well as current advances in clinical applications within the MSC therapy field. This text is a resource for both the basic life science and cell therapy researchers and includes a spectrum of review chapters from top experts in the field discussing clinical scale culture, regulatory issues, genetic engineering, disease specific applications and others.
  • Mesenchymal stem cells 2008, Springer Protocols
    Part I. Isolation of human multipotential stromal cells from bone marrow and adipose tissue. Isolation and culture of bone marrow-derived human multipotent stromal cells (hMSCs) / Margaret Wolfe ... [et al.]. Mesenchymal stem cells from adult bone marrow / Mark F. Pittenger. A method to isolate and purify human bone marrow stromal stem cells / Stan Gronthos and Andrew C. W. Zannettino. Adipose-derived stem cells / John K. Fraser ... [et al.]. Isolation of human adipose-derived stem cells from biopsies and liposuction specimens / Severine G. Dubois ... [et al.] -- Part II. Manipulation of human multipotential stromal cells. Colony forming unit assays for MSCs / Radhika Pochampally. Differentiation and characterization of human MSCs / Roxanne L. Reger, Alan H. Tucker, and Margaret R. Wolfe. Freezing harvested hMSCs and recovery of hMSCs from frozen vials for subsequent expansion, analysis, and experimentation / Roxanne L. Reger and Margaret R. Wolfe. Gene expression analysis at the single cell level using the human bone marrow stromal cell as a model : sample preparation methods / Beerelli Seshi. Assays of MSCs with microarrays / Joni Yöstalo, Radhika Pochampally, and Darwin J. Prockop. Gene delivery to mesenchymal stem cells / Reza Izadpanah and Bruce A. Bunnell -- Part III. Isolation and characterization of murine multipotential stromal cells from bone marrow. Isolation of mesenchymal stem cells from murine bone marrow by immunodepletion / Donald G. Phinney.
  • 1. Mesenchymal stromal cells in regressive medicine: a perspective / Peiman Hematti and Armand Keating -- 2. MSCs: changing hypotheses, paradigms, and controversies on mechanisms of action in repairing tissues / Darwin J. Prockop and Roxanne L. Reger -- 3. MSCs: the need to rethink / Paolo Bianco and Pamela G. Robey -- 4. Characterization of MSCs: from early studies to the present / Mark F. Pittenger -- 5. MSCs as therapeutics / Arnold I. Caplan -- 6. MSC niche for hematopoiesis / Daniel Lucas, Sandra Pinhol and Paul S. Frenette -- 7. Immunomodulatory properties of MSCs / Maria Ester Bernardo, Lynne M. Ball, Franco Locatelli and Willem E. Fibbe -- 8. MSCs and inmate immune responses: a balancing act / Krisztián Németh and Éva Mezey -- 9. MSCs: paracrine effects / Siddiraju V. Boregowda and Donald G. Phinney -- 10. Cross-talk between MSCs and their environments / Thomas P. Lozito and Rocky S. Tuan -- 11. Human MSCs from bone marrow, umbilical cord blood, and adipose tissue: all the same? / Patrick Wuchter and Anthony D. Ho -- 12. MSCs in solid tumors and hematological malignancies: from basic biology to therapeutic applications / Rodrigo Jaeamo, Erika Spaeth, Venkata Battula, Frank Marini and Michael Andreeff -- 13. MSC studies in large-animal models / Bruce A. Bunnell, Christine Gagliardi, and Maria Isabel Ribeiro Dias -- 14. Defining the potential of MSCs with a prenatal large animal model / Grac̦a Almeida-Porada, Christopher D. Orada and Esmail D. Zanjani -- 15. Bench-to-bedside development of MSC therapies: a multidisciplinary approach / Sowmya Viswanathan and Elizabeth J. Read -- 16. cGMP production of MSCs / Derek J. Hei and David H. McKenna, Jr. -- 17. MSCs: the US regulatory perspective / Adrian P. Gee -- 18. MSCs: clinical applications and European regulatory aspects / Jens Reinhardt, Egbert Flory, Isabel Büttel, Christa Schröder, Stefan Fricke, Vladan Vucinic, Michael Cross and Dietger Niederwieser -- 19. Stem cell treatments around the World: boon or bane?/ Alok Srivastava -- 20. Safety issues in MSC therapy / Minoo Battiwalla and A. John Barrett -- 21. In vivo imaging of MSCs / Jeff W.M. Bulte -- 22. National Heart, Lung and Blood Institute support of cellular therapies regenerative medicine / Traci Heath Mondoro and John Thomas -- 23. MSC therapy of inborn errors / Edwin M. Horwitz -- 24. MSCs for enhancement of hematopoietic progenitor cell engraftment and poor graft function / Paolo F. Caimi and Hillard M. Lazarus -- 25. MSCs ro graft-versus-host disease / Jakub Tolar, Katarina Le Blanc and Bruce R. Blazar -- 26. MSCs in pediatric hematopoietic stem cell transplantation / Lynne M. Ball, Maria Ester Bernardo, Franco Locatelli and R. Maarten Egeler -- 27. MSC for ex vivo expansion of umbilical cord blood cells / Ian K. McNiece, Simon N. Robinson, and Elizabeth J. Shpall -- 28. MSCs for autoimmune diseases / Alan Tyndall and Chiara Bocelli -- 29. MSCs for induction of solid organ allograft acceptance / Marc Dahlke, Philipp Renner and Elke Eggenhofer -- 30. MSCc for gastrointestinal disorders / Maria Ester Bernardo, Angela Maria Cometa and Franco Locatelli -- 31. MSCs for cardiac repair / Amish N. Raval and Timothy A. Hacker -- 32. MSCs for treatment of acute lung injury / Vladimir B. Serikov, Anna Krasnodembskaya, Jae Wood Lee, Marlowe W. Eldridge and Michael A. Matthay -- 33. MSCs for diabetes / Luca Inverardi, Giacomo Lanzoni, Juan Dominguez-Bendala and Camillo Ricordi -- 34. MSCs for renal repair / Anna M. Gooch and Christof Westenfelder -- 35. MSCs for the treatment of stroke, spinal cord injury, and traumatic brain injury: from bench work to clinical trials / Bing Yang, Ramy El Khoury, and Sean I. Savitz -- 36. MSCs in reconstructive surgery / Summer E. Hanson and Michael L. Bentz -- 37. MSCs in orthopedic surgery / Summer E. Hanson and Nicholas H. Maassen -- 30. Adipose tissue-derived MSCs: moving to the clinic / Pedro P. Carvalho, Manuela E. Gomes, Rui L. Reis and Jeffrey M. Gimble.
  • Methods in cell-matrix adhesion 2002, ScienceDirect
  • Methods in nano cell biology 2008, ScienceDirect
  • Micropatterning in cell biology. Part A-C pt. A-C, 2014, ScienceDirect
    Pt. B ScienceDirect
    Pt. C ScienceDirect
  • Microtubules, in vitro. 2nd ed. 2013, ScienceDirect
    Site-specific fluorescent labeling of tubulin / Kamalika Muhkerjee, Susan L. Bane -- Measuring microtubule persistence length using a microtubule gliding assay / Douglas S. Martin -- Structural studies of the doublecortin family of MAPs / Frank Fourniol, Mylène Perderiset, Anne Houdusse, Carolyn Moores -- Detection and quantification of microtubule detachment from centrosomes and spindle poles / Anutosh Ganguly, Hailing Yang, Fernando Cabral -- Regulation of tubulin expression by micro-RNAs : implications for drug resistance / Sharon Lobert, Mary E. Graichen -- Determining the structure-mechanics relationships of dense microtubule networks with confocal microscopy and magnetic tweezers-based microrheology / Yali Yang, Megan T. Valentine -- Studying mitochondria and microtubule localization and dynamics in standardized cell shapes / Andrea Pelikan, James Sillibourne, Stephanie Miserey-Lenkei, Frederique Carlier-Grynkorn, Bruno Goud, Phong T. Tran -- Going solo : measuring the motions of microtubules with an in vitro assay for TIRF microscopy / Kris Leslie, Niels Galjart -- Analysis of microtubules in isolated axoplasm from the squid giant axon / Yuyu Song, Scott T. Brady -- Imaging GTP-bound tubulin : from cellular to in vitro assembled microtubules / Hélène de Forges, Antoine Pilon, Christian Poüs, Franck Perez -- Tubulin-specific chaperones : components of a molecular machine that assembles the ... heterodimer / Guoling Tian, Nicholas J. Cowan -- Heterotrimeric G proteins and microtubules / Witchuda Saengsawang, Mark M. Rasenick -- Purification and biophysical analysis of microtubule-severing enzymes in vitro / Juan Daniel Diaz-Valencia, Megan Bailey, Jennifer L. Ross -- Measurement of in vitro microtubule polymerization by turbidity and fluorescence / Matthew Mirigian, Kamalika Mukherjee, Susan L. Bane, Dan L. Sackett -- Live-cell imaging of microtubules and microtubule-associated proteins in arabidopsis thaliana / Jessica Lucas -- Investigating tubulin posttranslational modifications with specific antibodies / Maria M. Magiera, Carsten Janke -- Purification and assembly of bacterial tubulin BtubA/B and constructs bearing eukaryotic tubulin sequences / José M. Andreu, María A. Oliva -- Microtubule-associated proteins and tubulin interaction by isothermal titration calorimetry / P.O. Tsvetkov, P. Barbier, G. Breuzard, V. Peyrot, F. Devred -- Methods for studying microtubule binding site interactions : zampanolide as a covalent binding agent / Jessica J. Field, Enrique Calvo, Peter T. Northcote, John H. Miller, Karl-Heinz Altmann, José Fernando Díaz -- Studying kinetochore-fiber ultrastructure using correlative light-electron microscopy / Daniel G. Booth, Liam P. Cheeseman, Ian A. Prior, Stephen J. Royle -- Fluorescence-based assays for microtubule architecture / Susanne Bechstedt, Gary L. Brouhard -- Structure-function analysis of yeast tubulin / Anna Luchniak, Yusuke Fukuda, Mohan L. Gupta -- Using MTBindingSim as a tool for experimental planning and interpretation / Julia T. Philip, Aranda R. Duan, Emily O. Alberico, Holly V. Goodson -- Imaging individual spindle microtubule dynamics in fission yeast / Judite Costa, Chuanhai Fu, Viktoriya Syrovatkina, Phong T. Tran.
  • Microtubules, in vivo. 1st ed. 2010, ScienceDirect
  • Midkine 2012, Springer
  • Mitochondria and cancer 2009, Springer
  • Mitochondria, practical protocols 2007., Springer Protocols
  • 1. Clinical Approach to the Diagnosis of Mitochondrial Disease / Dominic Thyagarajan, p. 1-23 -- 2. Mitochondrial DNA Mutations and Their Effects on Complex I Biogenesis: Implications for Metabolic Disease / Matthew McKenzie, p. 25-47 -- 3. Embryonic Stem Cells: A Signalling Perspective / Marios P. Stavridis, p. 49-68 -- 4. From Oocytes and Pluripotent Stem Cells to Fully Differentiated Fates: (Also) a Mitochondrial Odyssey / João Ramalho-Santos, Ana Sofia Rodrigues, p. 69-86 -- 5. From Pluripotency to Differentiation: The Role of mtDNA in Stem Cell Models of Mitochondrial Diseases / João Facucho-Oliveira, Tejal Kulkarni, p. 87-118 -- 6. The Role of Mitochondrial DNA in Tumorigenesis / Ka Yu Yeung, Adam Dickinson, p. 119-155 -- 7. Assisted Reproductive Technologies: The Potential to Prevent the Transmission of Mutant mtDNA from One Generation to the Next / Richard D. W. Kelly, Arsalan Mahmud, p. 157-183.
  • Mitochondrial medicine 2008, Springer
  • Introduction to Mitochondrial Oxidative Phosphorylation /Bernhard Kadenbach --Mitochondrial Dynamics: The Intersection of Form and Function /Andrew Ferree and Orian Shirihai --Biogenesis of Mitochondrial Proteins /Johannes M. Herrmann, Sebastian Longen, Daniel Weckbecker and Matthieu Depuydt --Assembly Factors of Human Mitochondrial Respiratory Chain Complexes: Physiology and Pathophysiology /Daniele Ghezzi and Massimo Zeviani --Supramolecular Organisation of the Mitochondrial Respiratory Chain: A New Challenge for the Mechanism and Control of Oxidative Phosphorylation /Giorgio Lenaz and Maria Luisa Genova --Molecular Mechanisms of Superoxide Production by the Mitochondrial Respiratory Chain /Stefan Dröse and Ulrich Brandt --Studies on the Function and Regulation of Mitochondrial Uncoupling Proteins /Richard K. Porter --Evolution of the Couple Cytochrome c and Cytochrome c Oxidase in Primates /Denis Pierron, Derek E. Wildman, Maik Hüttemann, Thierry Letellier and Lawrence I. Grossman --Reaction Mechanism of Mammalian Mitochondrial Cytochrome c Oxidase /Shinya Yoshikawa, Kazumasa Muramoto and Kyoko Shinzawa-Itoh --Phosphorylation of Mammalian Cytochrome c and Cytochrome c Oxidase in the Regulation of Cell Destiny: Respiration, Apoptosis, and Human Disease /Maik Hüttemann, Icksoo Lee, Lawrence I. Grossman, Jeffrey W. Doan and Thomas H. Sanderson --Individual Biochemical Behaviour Versus Biological Robustness: Spotlight on the Regulation of Cytochrome c Oxidase /Rabia Ramzan, Petra Weber, Bernhard Kadenbach and Sebastian Vogt --Bigenomic Regulation of Cytochrome c Oxidase in Neurons and the Tight Coupling Between Neuronal Activity and Energy Metabolism /Margaret T. T. Wong-Riley --Cytochrome c Oxidase and Its Role in Neurodegeneration and Neuroprotection /Susanne Arnold --The Many Clinical Faces of Cytochrome c Oxidase Deficiency /Salvatore DiMauro, Kurenai Tanji and Eric A. Schon.
  • "This book examines a unique assembly of coordinated mitochondrial functions that are important in regulating cell function and are of relevance in a myriad of pathophysiological situations, such as age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. The text covers themes essential for the maintenance of mitochondrial activity, including electron transport and energy production, mitochondrial biogenesis and dynamics, mitochondrial signaling, and apoptosis and autophagy. The book features chapters that are reviews of the important topics covered and are written by an impressive cadre of internationally recognized scientist"--Provided by publisher.
  • Introduction: Reminiscing on Models and Modeling / Robert B. Denman -- Probing Astrocyte Function in Fragile X Syndrome / Shelley Jacobs, Connie Cheng and Laurie C. Doering -- Neural Stem Cells / Maija Castrén -- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System / Theodore J. Price and Ohannes K. Melemedjian -- The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome / Stefan Kindler and Hans-Jürgen Kreienkamp -- Behavior in a Drosophila Model of Fragile X / Sean M. McBride, Aaron J. Bell and Thomas A. Jongens -- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome / Charles R. Tessier and Kendal Broadie -- Fragile X Mental Retardation Protein and Stem Cells / Abrar Qurashi, Xuekun Li and Peng Jin -- Manipulating the Fragile X Mental Retardation Proteins in the Frog / Marc-Etienne Huot, Nicolas Bisson, Thomas Moss and Edouard W. Khandjian --Exploring the Zebra Finch Taeniopygia guttata as a Novel Animal Model for the Speech-Language Deficit of Fragile X Syndrome / Claudia Winograd and Stephanie Ceman -- Neuroendocrine Alterations in the Fragile X Mouse / Abdeslem El Idrissi, Xin Yan, William L'Amoreaux, W. Ted Brown and Carl Dobkin -- Taking STEPs Forward to Understand Fragile X Syndrome / Susan M. Goebel-Goody and Paul J. Lombroso -- Fmr-1 as an Offspring Genetic and a Maternal Environmental Factor in Neurodevelopmental Disease / Bojana Zupan and Miklos Toth -- Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome / Michael R. Hunsaker, Gloria Arque, Robert F. Berman, Rob Willemsen and Renate K. Hukema -- Clinical Aspects of the Fragile X Syndrome / W. Ted Brown -- Fragile X Syndrome: A Psychiatric Perspective / Michael R. Tranfaglia -- Fragile X Syndrome and Targeted Treatment Trials / Randi Hagerman, Julie Lauterborn, Jacky Au and Elizabeth Berry-Kravis -- The Fragile X-Associated Tremor Ataxia Syndrome / Flora Tassone and Randi Hagerman -- Vignettes: Models in Absentia / Robert B. Denman.
  • Molecular biology of the cell. 4th ed. 2002, NCBI Bookshelf, Fulltext accessible by its search box
  • Molecular cell biology. 4th ed. 2000, NCBI Bookshelf
  • Molecular cytogenetics 2002, Springer Protocols
  • Speakers at the Symposium / Hartmann, D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Ju, Z. -- Alterations of systemic environment impair stem cell function during aging / Song, Z., Ju, Z. -- Novel insights into regulation of stem cell aging by aging of the niche and alterations in systemic factors / Geiger, H. -- Aging and hematopoietic malignancies / Gompf, A. -- Intestinal stem cell aging / Sperka, T., Rudolph, K.L. -- Molecular mechanisms of aging in muscle stem cells / Tümpel, S. -- Free radicals and stem cell aging / Guachalla, L.M. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Sperka, T., Nalapareddy, K., Rudolph, K.L.
  • Mortalin biology 2012, Springer
    Part 1.Structure and Function of Mortalin /Birth of Mortalin: Multiple Names, Niches and Functions Connecting Stress, Senescence and Cancer /Renu Wadhwa and Sunil C. Kaul --Mortalin's Machinery /Custer C. Deocaris, Sunil C. Kaul and Renu Wadhwa --The Role of Mortalin in Iron Homeostasis /Wen-I Luo and James A. Cowan --Functional Characteristics of Mortalin /Walter A. Baseler, Tara L. Croston and John M. Hollander --Part 2.Mortalin in Evolution2 Deocaris /Mortalin and Drosophila DmHsp22: Two Mitochondrial Chaperones Regulating Aging and Carcinogenesis /Marie Le Pécheur, Geneviève Morrow and Robert M. Tanguay --Mortalin in Invertebrates and The Induction of Apoptosis by Wild-Type p53 Following Defeat of Mortalin-Based Cytoplasmic Sequestration in Cancerous Clam Hemocytes /Charles W. Walker, Ben Low and S. Anne Böttger --Mortalin and Stem Cells: A Study from Planarians /Renata Batistoni --Part 3.Mortalin in Health and Disease /Mortalin in Cell Protection from Immune Attack /Moran Saar, Oren Moskovich and Zvi Fishelson --Mortalin in Neurological Diseases /Jinghua Jin, Jing Zhang, Travis J. Cook and Jake G. Hoekstra --Loss of Mortalin Function in Parkinson's Disease-Supporting the Mitochondrial Pathway of Neurodegeneration /Lena F. Burbulla and Rejko Krüger --Hsp75/mortalin and Protection from Ischemic Brain Injury /Robin E. White, Yi-Bing Ouyang and Rona G. Giffard --Catecholamine Regulated Protein (CRP40), A Splice Variant of Mortalin-2: Functional Role in CNS Disorders /Joseph P. Gabriele, Sarah E. Groleau, Ritesh P. Daya, Zdenek B. Pristupa and Ram K. Mishra --Chaperonopathies: Diseases in Which Mortalin and Other Hsp-Chaperones Play a Role in Etiology and Pathogenesis /Alberto J. L. Macario, Francesco Cappello and Everly Conway de Macario --Part 4.Mortalin and Cancer /Many Faces of Mortalin and Tid1 /Ohad Iosefson and Abdussalam Azem --Mortalin: A Positive Regulator of Centrosome Duplication and Amplification /Masayuki Kanai and Kenji Fukasawa --Mortalin Expression in Normal and Neoplastic Tissues /Angheliki Nomikos, Sinclair R. Dundas and Graeme I. Murray --Mortalin-p53 Interaction as a Target for Liver Cancer Therapy /Wen-Jing Lu, Nikki P. Lee, Renu Wadhwa and John M. Luk --Mortalin Targeting Gadgets for Cancer Therapy /Chae-Ok Yun and Renu Wadhwa --Part 5.Mortalin Based Technologies /Cell Internalizing Anti-Mortalin Antibody for Generation of Illuminating MSCs for Long-Term In vitro and In vivo Tracking /Toshimasa Uemura, Masanori Nishi, Sunil C. Kaul and Renu Wadhwa --Mortalin Staining Pattern as a Reporter for Cell Based Anti-Cancer Drug Screening /Ran Gao, Zeenia Kaul, Tomoko Yaguchi and Renu Wadhwa --Cell Internalizing Anti-mortalin Antibody as a Nanocarrier /Zeenia Kaul, Tomoko Yaguchi, Renu Wadhwa and Sunil C. Kaul.
  • Post-transcriptional Control of Gene Expression During Mouse Oogenesis /Hugh J. Clarke --Polarity and Asymmetry During Mouse Oogenesis and Oocyte Maturation /Malgorzata Kloc, Rafik M. Ghobrial, Ewa Borsuk and Jacek Z. Kubiak --Chromatin Structure and ATRX Function in Mouse Oocytes /Rabindranath De La Fuente, Claudia Baumann and Maria M. Viveiros --Cyclin B in Mouse Oocytes and Embryos: Importance for Human Reproduction and Aneuploidy /Zbigniew Polański, Hayden Homer and Jacek Z. Kubiak --Src Protein Kinases in Mouse and Rat Oocytes and Embryos /Mattan Levi, Lihi Ninio-Mani and Ruth Shalgi --Gradual Meiosis-To-Mitosis Transition in the Early Mouse Embryo /Aurélien Courtois and Takashi Hiiragi --Maternal Control of Mouse Preimplantation Development /Wenjing Zheng and Kui Liu --Preimplantation Mouse Embryo: Developmental Fate and Potency of Blastomeres /Aneta Suwińska --Creation of Trophectoderm, the First Epithelium, in Mouse Preimplantation Development /Yusuke Marikawa and Vernadeth B. Alarcon --Cell Lineage Allocation Within the Inner Cell Mass of the Mouse Blastocyst /Panagiotis Xenopoulos, Minjung Kang and Anna-Katerina Hadjantonakis --Formation of Distinct Cell Types in the Mouse Blastocyst /Samantha A. Morris and Magdalena Zernicka-Goetz --Cell Movements in the Egg Cylinder Stage Mouse Embryo /Bradley Joyce and Shankar Srinivas --Balancing the Dose in the Mouse /Mary E. Donohoe --Mouse Oviduct Development /C. Allison Stewart and Richard R. Behringer --Cell Lineages, Growth and Repair of the Mouse Heart /Fabienne Lescroart and Sigolène M. Meilhac --Cellular Reprogramming During Mouse Development /Zoë D. Burke, Gabriela Miron-Buchacra and David Tosh --Differentiation of Definitive Endoderm from Mouse Embryonic Stem Cells /Peter T. W. Kim and Christopher J. Ong --Mouse and Human Pluripotent Stem Cells and the Means of Their Myogenic Differentiation /I. Grabowska, K. Archacka, A. M. Czerwinska, M. Krupa and M. A. Ciemerych --Stem Cells and Corneal Epithelial Maintenance: Insights from the Mouse and Other Animal Models /Richard L. Mort, Panagiotis Douvaras, Steven D. Morley, Natalie Dorà and Robert E. Hill, et al. --Mouse-Induced Pluripotent Stem Cells /Hui Zhang and Ying Jin --Aging in the Mouse and Perspectives of Rejuvenation Through Induced Pluripotent Stem Cells (iPSCs) /Ken-ichi Isobe, Zhao Cheng, Sachiko Ito and Naomi Nishio.
  • An introduction to muscle development in drosophila / Helen Sink -- The muscle pattern of drosophila / Volker Hartenstein -- Mesoderm formation in the drosophila embryo / Noriko Wakabayashi-Ito and Y. Tony Ip -- Development of the cardiac musculature / Rolf Bodmer -- Development of the somatic gonad and fat bodies / Mark Van Doren -- Development of the larval visceral musculature / Hsiu-Hsiang Lee, Stephane Zaffran and Manfred Frasch -- Development of the larval somatic musculature / Ana Carmena and Mary Baylies -- Muscle morphogenesis: the process of embryonic myoblast fusion / Susan M. Abmayr and Kiranmai S. Kocherlakota -- Muscle attachment sites-where migrating muscles meet their match / Talila Volk -- Neuromuscular development: connectivity and plasticity / Louise Nicholson and Haig Keshishian -- Metamorphosis and the formation of the adult musculature / Devkanya Dutta and K. VijayRaghavan -- Molecular basis of muscle structure / Jim O. Vigoreaux -- Whole genome approaches to studying drosophila muscle development / Eileen E.M. Furlong -- Comparison of muscle development in drosophila and vertebrates / Michael V. Taylor.
  • Nanomaterial 2014, Springer
    Presence in, and release of, nanomaterials from consumer products / Yu Yang and Paul Westerhoff -- Nanoparticle aggregation: principles and modeling / Wen Zhang -- Influences of nanomaterials on the barrier function of epithelial cells / Shariq Ali and Erik Rytting -- Engineered nanoparticles induced brush border disruption in a human model of the intestinal epithelium / James J. Faust, Benjamin M. Masserano, Adam H. Mielke, Anup Abraham, and David G. Capco -- Nanoparticles: cellular uptake and cytotoxicity / Isaac M. Adjei, Blanka Sharma and Vinod Labhasetwar -- Atomic force microscopy study of the interaction of DNA and nanoparticles / Kungang LI, Songyan Du, Steven Van Ginkel, and Yongsheng Chen -- Intracellular signal modulation by nanomaterials / Salik Hussain, Stavros Garantziotis, Fernando Rodrigues-Lima, Jean-Marie Dupret, Armelle Baeza-Squiban, Sonja Boland -- Nanomaterials: impacts on cells and cell organelles / Željka Krpetić, Sergio Anguissola, David Garry, Philip Kelly and Kenneth A. Dawson -- Design, synthesis, and functionalization of nanoparticles for therapeutic drug delivery / Taraka Sai Pavan Grandhi and Kaushal Rege -- Preparation of nanoscale pulmonary drug delivery formulations by spray drying / Adam Bohr, Christian A. Ruge, and Moritz Beck-Broichsitter -- Nanomedicine: the promise and challenges in cancer chemotherapy / Youssef W. Naguib and Zhengrong Cui -- Transgenerational effects of NMs / Anna Poma, Sabrina Colafarina, Gabriella Fontecchio, and Giuseppe Chichiricco -- Stem cells and nanomaterials / Maria-Claude Hofmann.
  • Natural killer cells 2010, Springer
  • Natural killer cells 2010, ScienceDirect
    Chapter 1, Developmental stages and pathways of NK cell maturation / Bartosz Grzywacz, Jeffery S. Miller, Michael R. Verneris -- Chapter 2. Developmental origins of thymus-derived natural killer cells / James R. Carlyle, Juan C. Zúñiga-Pflücker -- Chapter 3. Interferon-producing killer dendritic cells (IKDC) / Franck Housseau -- Chapter 4. Natural killer cells in cancer / Petter Höglund, Hans-Gustaf Ljunggren -- Chapter 5. NK cell immune recognition: NKG2D ligands and stressed cells / Carlos López-Larrea, Alejandro López-Soto, Segundo González -- Chapter 6. NK cell KIR heterogeneity and evolution / Makoto Yawata, Nobuyo Yawata -- Chapter 7. Signalling events in natural killer cells / P.K. Epling-Burnette, Sheng Wei, Julie Y. Djeu -- Chapter 8. Human natural killer cell development / Edward L. Briercheck, Aharon G. Freud, Michael A. Caligiuri -- Chapter 9. Isolation, culture and propagation of natural killer cells / Michael Magee, Lazar N. Vujanovic, Lisa H. Butterfield, Nikola L. Vujanovic -- Chapter 10. The localization and migration of natural killer cells in health and disease / Vasileios Bekiaris, Peter J.L. Lane -- Chapter 11. Receptors on NK cells / Noam Stern-Ginossar, Ofer Mandelboim -- Chapter 12. Development and testing of NK cell lines / Hans Klingemann -- Chapter 13. NK cell-derived cytokines and delivery: NK cell synapses / Claudia Semino, Anna Rubartelli -- Chapter 14. NK cells as recipients of cytokine signals / Tara J. Loux, Michael T. Lotze, Herbert J. Zeh III -- Chapter 15. NK cells and chemokines / Angela Gismondi, Giovanni Bernardini, Angela Santoni -- Chapter 16. Natural killer cytolytic activity / Lesley R. de Armas, Eckhard R. Podack -- Chapter 17. Illuminating intranodal natural killer cell behaviour using two-photon microscopy / Kym R. Garrod, Michael D. Cahalan -- Chapter 18. Dendritic cells and NK cells / Amy K. Wesa, Robbie B. Mailliard -- Chapter 19. NK and NKT cells: The innate-adaptive interface including humoral responses / Jeff Subleski, Jonathan M. Weiss, Robert H. Wiltrout, John R. Ortaldo -- Chapter 20. NK cell and endothelial cell interactions / Angela Gismondi, Claudia Carlino, Helena Stabile, Angela Santoni -- Chapter 21. Natural killer cell/epithelial interactions / Taisuke Ito, Masao Takei, Ralf Paus -- Chapter 22. NK cell-T cell interactions / Benedict J. Chambers -- Chapter 23. NK cells and NKT cells in cutaneous disorders / Anna Balato, Anthony A. Gaspari -- Chapter 24. Natural killer cells in the respiratory tract / Borna Mehrad --Chapter 25. Intestinal natural killer cells / Martin R. Goodier -- Chapter 26. Natural killer cells in the liver / Shiguang Qian, Jia Fan, Shuang-Jian Qiu, Yong-sheng Xiao, Lina Lu -- Chapter 27. Natural killer cells in the spleen and lymph node / Alex Karlsson-Parra -- Chapter 28. Nature killer cells in the central nervous system / Fu-Dong Shi, Richard M. Ransohoff -- Chapter 29. NK cells in the eye / Jerry Y. Niederkorn -- Chapter 30. NK cells and reproduction / Ashley Moffett, Victoria H. Male -- Chapter 31. Identification of natural killer cells in tissues and their isolation / Paolo Carrega, Erika Montalto, Guido Ferlazzo -- Chapter 32. Natural killer cell immune regulation: Coordination of immune function in tissues / Lorenzo Moretta, Alessandro Moretta -- Chapter 33. Natural killer cells and transplantation / Benjamin M. Matta, Angus W. Thomson -- Chapter 34. Natural killer cells and autoimmunity / Christian Münz -- Chapter 35. Interaction of NK cells with bacteria / Kenji Chamoto, Daiko Wakita, Shinichi Koizumi, Kazutaka Masuko, Takayuki Ikeda, Rieko Mitamura, Takashi Nishimura -- Chapter 36. Natural killer cells and human immunodeficiency virus / Domenico Mavilio, Anne Hosmalin, Daniel Scott-Algara -- Chapter 37. Cytomegalovirus infection and NK cells / Jerome D. Coudert, Christopher E. Andoniou, Mariapia A. Degli-Esposti -- Chapter 38. Natural killer cells in allergy / Syh-Jae Lin, Yen-Chang Lee, Dah-Chin Yan, Ming-Ling Kuo -- Chapter 39. Natural killer cells in wound healing / Jussi Liippo, Mervi Toriseva, Veli-Matti Kähäri -- Chapter 40. Natural killer cells in atherosclerosis / Godfrey S. Getz, Catherine A. Reardon -- Chapter 41. Natural killer cells in leukaemia / Jérôme Rey, Cyril Fauriat, Alessandro Moretta, Régis Costello, Daniel Olive -- Chapter 42. Natural killer cells and allogeneic haematopoietic cell transplantation / Andrea Velardi -- Chapter 43. Clinical trials of NK cells for cancer / Sarah Cooley, Jeffrey S. Miller -- Chapter 44. Natural killer cells and hepatitis C virus infection / Michael A. Nalesnik, Tatsuya Kanto -- Chapter 45. Natural killer cells and the biology of parasitism / Marianne A. Bryan, Karen A. Norris -- Chapter 46. Lymphoproliferative disorders of natural killer cells / William G. Morice -- Chapter 47. Natural killer cell induction of tolerance / Lina Lu, Alexandra Y. Zhang, William L. Camp, Shiguang Qian -- Chapter 48. Genetic engineering of natural killer cells / Stephen R. Goding, Per H. Basse -- Chapter 49. NK cell-mediated target cell death / Beverly Z. Packard, Akira Komoriya, David S. Ucker -- Chapter 50. NK-cell tracking using non-invasive imaging modalities / Priyanka Jha, Verena Reinhart, Christiane Knopp, Siyuan Liu, Winfried S. Wels, Michael F. Wendland, Heike Daldrup-Link.
  • Natural killer T cells 2012, Springer
    Introduction : mechanisms of NKT-cell-mediated adjuvant activity and function of iPS-derived NKT cells / Masaru Taniguchi ... [et al.] -- Structure and recognition of antigens for invariant NKT cells / Bo Pei and Mitchell Kronenberg -- Invariant NKT cell-based vaccine strategies / John-Paul Jukes ... [et al.] -- Immune regulation of tumor immunity by NKT cells / Jessica J. O'Konek, Jay A. Berzofsky, and Masaki Terabe -- The regulation of CD1d+ and CD1d- tumors by NKT cells : the roles of NKT cells in regulating CD1d+ and CD1d- tumor immunity / Jianyun Liu, Gourapura J. Renukaradhya, and Randy R. Brutkiewicz -- DC-based immunotherapy targeting NKT cells / Shin-ichiro Fujii and Kanako Shimizu -- Therapeutic approaches utilising NKT cells / Stephen R. Mattarollo and Mark J. Smyth -- NKT cells or cancer patients and how models can inform therapeutic plans / Mark A. Exley, Lydia Lynch, and Michael Nowak -- Understanding the role of natural killer T cells in hematologic malignancies : progress and challenges / Natalia Neparidze and Madhav V. Dhodapkar -- Clinical trials with alpha-galactosylceramide (KRN7000) in advanced cancer / Famke L. Schneiders ... [et al.] -- Clinical trials of invariant natural killer T cell-based immunotherapy for cancer / Shinichiro Motohashi, Yoshitaka Okamoto, and Toshinori Nakayama.
  • Neural crest cells 2014, ScienceDirect
  • Defining neural stem cells and their role in normal development of the nervous system / Sally Temple -- Embryonic stem cells and neurogenesis / Robin L. Wesselschmidt -- The cellular and molecular properties of multipotent neural stem cells / Scott R. Hutton and Larysa H. Pevny -- Multipotent stem cells in the embryonic nervous system / Chian-Yu Peng ... [et al.] -- Neural crest formation and diversification / Marcos S. Simões-Costa ... [et al.] -- Glial nature of adult neural stem cells : neurogenic competence in adult astrocytes / William W. Hwang, Arturo Alverez-Buylla and Daniel A. Lim -- Neural stem cell death regulation in nervous system development and disease / K.C. Walls and Kevin A. Roth -- Stem cells of adult olfactory epithelium / James E. Schwob, Woochan Jang and Eric H. Holbrook -- Retinal stem cells / Carolina B. Del Debbio ... [et al.] -- Transdifferentiation in the nervous system / Ying Liu and Mahendra S. Rao -- Neural and dopaminergic differentiation of human pluripotent stem cells / Olga Momcilovic and Xianmin Zeng -- Mobilization of neural stem cells in the adult central nervous system / Harish Babu, Theo D. Palmer and Fred H. Gage -- Stem cell pathways in brain tumors / Justin D. Lathia ... [et al.].
  • Neural stem cells 2002, Springer Protocols
  • Neural stem cells. 2nd ed. 2008, Springer Protocols
    Definitions and criteria for stem cells / Leslie P. Weiner -- Neural stem cells and the future treatment of neurological diseases : raising the standard / Jaime Imitola and Samia J. Khoury -- Neural differentiation of human embryonic stem cells / Mirella Dottori and Martin F. Pera -- Generating neurons from stem cells / Andreas Androutsellis-Theotokis ... [et al.] -- Isolation of neural stem and precursor cells from rodent tissue / Yuanyuan Wu ... [et al.] -- Adult rodent spinal cord-derived neural stem cells : isolation and characterization / Lamya S. Shihabuddin -- Adult neural stem cells / Rossella Galli, Angela Gritti, and Angelo L. Vescovi -- Olfactory ensheathing cells : isolation and culture from the neonatal olfactory bulb / Susan C. Barnett and A. Jane Roskams -- Culturing olfactory ensheathing cells from the mouse olfactory epithelium / Miranda Richter, Kathryn Westendorf, and A. Jane Roskams -- Production and characterization of immortal human neural stem cell line with multipotent differentiation property / Seung U. Kim ... [et al.] -- Preparation of neural progenitors from bone marrow and umbilical cord blood / Shijie Song and Juan Sanchez-Ramos --Production of neurospheres from CNS tissue / Gregory P. Marshall II ... [et al.] -- Nuclear transfer to study the nuclear reprogramming of human stem cells / Shigeo Saito ... [ et al.] -- Clonal analyses and cryopreservation of neural stem cell cultures / Angela Gritti, Rossella Galli, and Angelo L. Vescovi -- Telomere neurobiology / Mark P. Mattson, Peisu Zhang, and Aiwu Cheng -- Chromosomal mosaicism in neural stem cells / Suzanne E. Peterson ... [et al.] -- In vitro assays for neural stem cell differentiation : induction of dopaminergic phenotype / Marcel M. Daadi -- In vitro migration assays of neural stem cells / Pascale Durbec .. [et al.] -- Measuring apoptosis in neural stem cells / Brett T. Lund and Eve E. Kelland -- Markers of adult neural stem cells / Eric Wexler -- Differential gene expression in ES-derived neural stem cells by using RT-PCR / Nicole Slawny, Crystal Pacut, and Theresa E. Gratsch -- Microfluidic devices for high-throughput gene expression profiling of single hESC-derived neural stem cells / Yan Chen and Jiang F. Zhong --Electroporation strategies for genetic manipulation and cell labeling / Terence J. Van Raay, Rhonda T. Lassiter, and Michael R. Stark -- Novel and immortalization-based protocols for the generation of neural CNS stem cell lines for gene therapy approaches / Luciano Conti and Elena Cattaneo -- Identification of newborn cells by BrdU labeling and immunocytochemistry in vivo / Sanjay S. Magavi and Jeffrey D. Macklis -- Immunocytochemical analysis of neuronal differentiation / Sanjay S. Magavi and Jeffrey D. Macklis -- Neuroanatomical tracing of neuronal projections with Fluoro-Gold / Lisa A. Catapano, Sanjay S. Magavi, and Jeffrey D. Macklis -- Labeling stem cells in vitro for identification of their differentiated phenotypes after grafting into the CNS / Qi-lin Cao, Stephen M. Onifer, and Scott R. Whittemore -- Optimizing stem cell grafting into the CNS / Scott R. Whittemore ... [et al.] -- Routes of stem cell administration in the adult rodent / Alison E. Willing ... [et al.]
  • "The importance of the regulation of salt is of clinical relevance given its relation to the "epidemic" of high blood pressure and that virtually all foods throughout the EU and USA will be mandated to reduce their salt content. This book covers virtually all aspects of the innate drives of thirst and salt, including transduction, sensory mechanism, afferent systems, organization, CNS integrative circuitry, and efferent pathways and effectors systems. It also covers the addition aspects of salt appetites and the orexigenic aspects, as well as other emerging topics in this field"--Provided by publisher.
  • Altered histone deacetylase activity and iNOS expression in cells isolated from induced sputum of COPD patients treated with tiotropium -- Involvement of NF-[kappa]B and muscle specific E3 ubiquitin ligase MuRF1 in cigarette smoke-induced catabolism in C2 myotubes -- Siglec-8 in induced sputum of COPD patients -- Essential amino acid leucine and proteasome inhibitor MG132 attenuate cigarette smoke induced catabolism in C2 myotubes -- Smoking denial in cardiovascular disease studies -- Differential effects of kainic acid lesions in medullary raphe on cough and sneeze in anesthetized rabbits -- Detection of Chlamydophila pneumoniae antigens in patients with chronic cough -- Antioxidant activity of herbal polysaccharides and cough reflex -- Cytoglobin and neuroglobin in the human brainstem and carotid body -- Flow cytometry in the diagnosis of influenza -- Accuracy of rapid influenza detection test in diagnosis of influenza A and B viruses in children less than 59 months old -- Virological monitoring of influenza activity and influenza-like illness in the epidemic season 2011-2012 in Poland -- Incidence of Chlamydophila pneumoniae infection in children during 2007-2010 -- Clinical features and outcomes of influenza A and B infections in children -- Respiratory complications in children hospitalized with Varicella -- Hyponatremia in children hospitalized due to pneumonia -- In vitro sensitivity of Acinetobacter baumannii and Pseudomonas aeruginosa to carbapenems among intensive care unit patients -- Prevalence of acute respiratory tract diseases among soldiers deployed for military operations in Iraq and Afghanistan --In vitro susceptibility of Staphylococci and Enterococci to vancomycin and teicoplanin -- Sinusitis in people living in the Medieval Ages -- Immunization coverage against capsular bacteria in splenectomized patients -- Umbilical cord blood gas content, postnatal state of neonates, and lactation after caesarean and natural childbirth -- Respiratory function in pregnant women -- Lung function in patients with gastro-esophageal reflux disease and respiratory symptoms -- Efficacy of noninvasive mechanical ventilation in obese patients with chronic respiratory failure -- Near-infrared hemoencephalography for monitoring blood oxygenation in prefrontal cortical areas in diagnosis and therapy of developmental dyslexia -- Occlusal stabilization splint therapy in orofacial pain and tension-type headache -- Dynamics of upper airways during the Müller maneuver in healthy subjects: a cine MRI study -- EMG analysis of human inspiratory muscle resistance to fatigue during exercise -- Assessment of temporomandibular joint disease -- Spirometry Day: a means to enhance social knowledge on respiratory diseases -- Lung function in divers -- Influence of traffic-related air pollutants on lung function -- Fractional exhaled nitric oxide in clinical trials: an overview -- Real-time breath analysis in type 2 diabetes patients during cognitive effort -- Exhaled nitric oxide in specific inhalation challenge -- Integration of simulated multipotential signals: the role of integration window width and of the number of spikes --Functional and topographic concordance of right atrial neural structures inducing sinus tachycardia -- Occurrence of disseminated intravascular coagulation in 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced pneumonia in the rat -- Implementation of non-invasive methods in the diagnosis of diisocyanate-induced asthma -- Evaluation of a 4-steps-1-day whole body challenge protocol for the diagnosis of occupational asthma due to diisocyanates -- Occupational allergic respiratory diseases in garbage workers: relevance of molds and actinomycetes -- Th1, Th2, Th17, and regulatory cytokines in children with different clinical forms of allergy -- Soluble receptor for urokinase plasminogen activator in community-acquired pneumonia in children -- Hypersensitivity pneumonitis due to metalworking fluids: how to find the antigens -- Angiogenic axis angiopoietin-1 and angiopoietin-2/tie-2 in non-small cell lung cancer: a bronchoalveolar lavage and serum study -- Cancer incidence in pulmonary vasculitis -- Influence of delays in diagnosis and treatment on survival in small cell lung cancer -- Familial idiopathic pulmonary fibrosis -- High resolution computed tomography in 2-year follow-up of stage I sarcoidosis -- Altruistic aptitude: age-dependent influence of temperament and emotional intelligence -- Effect of socio-economic status on quality of life in people affected with respiratory allergy -- Exposure to paracetamol and antibiotics in early life and elevated risk of asthma in childhood -- Health behaviors and quality of life among patients with chronic respiratory disease -- Attitudes toward euthanasia among Polish physicians, nurses and people who have no professional experience with the terminally ill -- Death as a result of violent asphyxia in autopsy reports -- Respiratory and systemic infections in children with severe aplastic anemia on immunosupressive therapy.
  • Nature of neurons and their specialized membranes -- DHA contributes both benefits and risks to mammals -- Use it or lose it concept of brain health is linked to DHA -- Evolution and DHA : redefining the DHA principle -- DHA is king omega for maximizing mental speed -- DHA improves energy efficiency in neurons -- Wild conformational dynamics of DHA might save energy by sealing stretch-induced defects as fast as they occur in membranes -- Lipid whisker model and water-wire theory of energy uncoupling in neurons -- Neurons boost their energy state by using powerful antioxidant systems to protect their membranes against damage -- Oxygen-dependent damage (lipid peroxidation) of DHA membranes of neurons is inevitable and requires novel mechanisms for long-term protection -- Revised mitochondrial theory of aging and brain span -- Development of dual energy pacemaker theory of aging : role of the membrane -- Membranes and cancer -- Parkinson's disease -- Prion diseases -- Brain trauma-induced dementia -- Alzheimer's disease.
  • Neuroprotection methods and protocols 2007, Springer Protocols
    Neuronal death and neuroprotection : a review / Mariaelena Repici, Jean Mariani, and Tiziana Borsello -- The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures / Anthony C. Lau, Hong Cui, and Michael Tymianski -- A modified silver technique (de Olmos Stain) for assessment of neuronal and axonal degeneration / Tatyana I. Tenkova and Mark P. Goldberg -- Model of acute injury to study neuroprotection / Michal Schwartz and Jonathan Kipnis -- Organotypic entorhino-hippocampal slice cultures : a tool to study the molecular and cellular regulation of axonal regeneration and collateral sprouting in vitro / Domenico Del Turco and Thomas Deller -- Role of Nrf2-dependent ARE-driven antioxidant pathway in neuroprotection / Jiang Li ... [et al.] -- Biochemical methods to assess the coupling of brain energy metabolism in control and disease states / Jennifer Zechel, W. David Lust, and Michele Puchowicz -- A method for isolating prosurvival targets of NF-[kappa]B/rel transcription factors / Christian Kuntzen ... [et al.] -- Functional cloning of genes regulating apoptosis in neuronal cells / Roberta Visconti and Luciano D'Adamio -- Characterization of mRNA expression in single neurons / David M. Lin ... [et al.] -- Brain on a chip : a method to detect novel neuroprotective candidate targets / Yang Tang and Myriam Bernaudin -- Intracerebral infusion of neurotrophic factors / Theo Hagg -- Synthesis of cell-penetrating peptides and their application in neurobiology / Gunnar P.H. Dietz and Mathias Bähr -- The stem cells as a potential treatment for neurodegeneration / Ferrari Daniela, Angelo Luigi Vescovi, and Daniele Bottai -- In vivo tomographic imaging studies of neurodegeneration and neuroprotection : a review / Rikki N. Waterhouse and Jun Zhao.
  • Neutron capture therapy 2012, Springer
  • Neutrophil methods and protocols 2007, Springer Protocols
    The role of neutrophils in the immune system: an overview / H.L. Malech -- Subcellular fractionation of human neutrophils and analysis of subcellular markers / L. Udby and N. Borregaard -- Rac and Rap GTPase activation assays / U.G. Knaus, A. Bamberg and G.M. Bokoch -- Measurement of phospholipid metabolism in intact neutrophils / S. Sergeant and L.C. McPhail -- Analysis of protein phosphorylation in human neutrophils / J. El-Benna and P.M.-C. Dang -- Mitogen-activated protein kinase assays / M. Torres -- Transduction of proteins into intact neutrophils / T. Zhao and G.M. Bokoch -- Optical methods for the measurement and manipulation of cytosolic free calcium in neutrophils / E.J. Hillson, S. Dewitt and M.B. Hallett -- Analysis of electrophysiological properties and responses of neutrophils / D. Morgan and T.E. DeCoursey -- Analysis of neutrophil apoptosis / E.L. Taylor ... [et al.] -- Optical and fluorescence detection of neutrophil integrin activation / U.Y. Schaff ... [et al.] -- Analysis of neutrophil polarization and chemotaxis / M.A. Lokuta, P.A. Nuzzi and A. Huttenlocher -- Quantifying and localizing actin-free barbed ends in neutrophils / M. Glogauer -- Measurement of neutrophil adhesion under conditions mimicking blood flow / M.A. Jutila ... [et al.] -- Model systems to investigate neutrophil adhesion and chemotaxis / N.A. Louis, E. Campbell and S.P. Colgan -- Immunofluorescence and confocal microscopy of neutrophils / L.-A.H. Allen -- Assessment of phagosome formation and maturation by fluorescence microscopy / B.E. Steinberg and S. Grinstein -- Analysis of neutrophil membrane traffic during phagocytosis / P. Loennbro, P. Nordenfelt and H. Tapper -- Analysis of neutrophil bactericidal activity / J.N. Green, C.C. Winterbourn and M.B. Hampton -- A skin chamber technique as a human model for studies of aseptic inflammatory reactions / P. Follin and C. Dahlgren -- Measurement of respiratory burst products generated by professional phagocytes / C. Dahlgren, A. Karlsson and J. Bylund -- The K-562 cell model for analysis of neutrophil NADPH oxidase function / T.L. Leto ... [et al.] -- Cell-free assays: the reductionist approach to the study of NADPH oxidase assembly, or "all you wanted to know about cell-free assays but did not dare to ask" / S. Molshanski-Mor ... [et al.] -- Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics / R.M. Taylor and A.J. Jesaitis -- Genome-scale transcript analyses in human neutrophils / S.D. Kobayashi, D.E. Sturdevant and F.R. DeLeo -- Fast and accurate quantitative analysis of cytokine gene expression in human neutrophils by reverse transcription real-time PCR / N. Tamassia, M.A. Cassatella and F. Bazzoni -- Detection of intact transcription factors in human neutrophils / P.P. McDonald and R.D. Ye -- Disorders of neutrophil function: an overview / M.C. Dinauer -- Diagnostic assays for chronic granulomatous disease and other neutrophil disorders / H.Z. Elloumi and S.M. Holland -- Diagnostic assays for myeloperoxidase deficiency / W.M. Nauseef.
  • Gene Expression Profiling and Regulatory Networks in Single Cells /Fumio Arai, Kentaro Hosokawa, Yoshiko Matsumoto, Hirofumi Toyama and Toshio Suda --Cell Fate Regulatory Networks /Sonya J. Ridden and Ben D. MacArthur --Noise in Regulatory Networks /Srinandan Dasmahapatra --Generalised Modelling in Systems Biology /Thilo Gross --Relative Quantification Mass Spectrometry Using iTRAQ Isobaric Tags /Richard D. Unwin, Emma Carrick and Anthony D. Whetton --Deciphering Protein Complexes and Protein Interaction Networks for Stem Cell Pluripotency /Jianlong Wang --Omics Era in Stem Cell Research: Data Integration of Multi-regulatory Layers /Ana Sevilla, Benjamin Trinite and Ihor R. Lemischka --High Throughput Affinity Purification and Mass Spectrometry to Determine Protein Complex Interactions /Anna Malovannaya, Rainer B. Lanz, Bert W. O'Malley and Jun Qin --Network Pharmacology to Aid the Drug Discovery Process /Ruth Dannenfelser, Huilei Xu, Catherine Raimond and Avi Ma'ayan --What Can Networks Do for You? /Bernhard M. Schuldt, Franz-Josef Müller and Andreas A. Schuppert.
  • Part 1.Basic Science and Experimental Studies on Stem Cell Mobilization --Preclinical Experience with AMD3100 for Mobilization of Hematopoietic Stem and Progenitor Cells --Molecular Pharmacology of CXCR4 Inhibition --Combination Strategies for Stem Cell Mobilization Targeting CXCR4 and S1P Receptors --Should We Stay or Should We Go Now? --Cell Adhesion and Mobilization Pathways of Hematopoietic Cells --Role of the CXCR4/CXCL12 Axis in Hematopoietic Stem Cell Trafficking --Part 2.Clinical Studies on Stem Cell Mobilization --Front matter --Early Studies of AMD3100/Plerixafor in Healthy Volunteers --The Current Role of Plerixafor in Stem Cell Mobilization for Hematopoietic Stem Cell Transplantation --Experience with Apheresis Procedures After Plerixafor Mobilisation --Influence of Different Stem Cell Mobilization Strategies on Graft Composition and Outcome of Autologous or Allogeneic Transplantation --Relevance and Clinical Implications of Tumor Cell Mobilization in Autologous Transplantation of Multiple Myeloma and Non-Hodgkin's Lymphoma --Plerixafor: Data from the Compassionate Use Program --Stem Cell Mobilization with Chemomobilization Plus Plerixafor in Hard-to-Mobilize Patients: The Experience at Kuopio University Hospital, Finland --Blood Stem Cell Mobilization in Solid Tumors: Experience with Plerixafor and Alternative Ways of Hematopoietic Stem Cell Mobilization --Mobilization with Chemotherapy + G-CSF + Plerixafor in Europe: The Italian Experience --Experience with Plerixafor in Poor Mobilizers --CXCR4 Antagonists --Part 3.CXCR4 Antagonists for Treatment of Leukemias and Solid Tumors --Front matter --Application of CXCR4 Inhibitors in Leukemia --CXCR4 Antagonists for the Treatment of CML --Targeting CXCR4 in Chronic Lymphocytic Leukemia: Preclinical Rationale and Early Clinical Experience --CXCR4-Blockade for Treatment of Breast Cancer --Molecular Imaging of CXCR4 Receptor Expression in Tumors --Part 4.Novel applications --Potential Use of CXCR4 Antagonists to Mobilize Endothelial and Mesenchymal Stem Cells --Strategies to Enhance Hematopoietic Stem Cell Engraftment Following Transplantation --Mobilization for Gene Therapy.
  • Nuclear dynamics 2007, Springer
  • Section A. Cell Nucleus: Organization & MechanoBiology -- Chapter 1. Fluorescence Fluctuation Microscopy to Reveal 3D Architecture and Function in the Cell Nucleus / Thorsten Lenser, Klaus Weisshart, Tobias Ulbricht, Karolin Klement, Peter Hemmerich -- Chapter 2. Studying Histone Modifications and Their Genomic Functions by Employing Chromatin Immunoprecipitation and Immunoblotting / Ranveer S. Jayani, Praveena L. Ramanujam, Sanjeev Galande -- Chapter 3. Dynamic Organization of Chromatin Assembly and Transcription Factories in Living Cells / Bidisha Sinha, Dipanjan Bhattacharya, Deepak Kumar Sinha, Shefali Talwar, Shovamayee Maharana, Soumya Gupta, G.V. Shivashankar -- Chapter 4. Manipulation and Isolation of Single Cells and Nuclei / Swee Jin Tan, Qingsen Li, Chwee Teck Lim -- Chapter 5. Beyond Lamins: Other Structural Components of the Nucleoskeleton / Zhixia Zhong, Katherine L. Wilson, Kris Noel Dahl -- Chapter 6. Altered Mechanical Properties of the Nucleus in Disease / Maria Lucia Lombardi, Jan Lammerding -- Chapter 7. Theoretical Concepts and Models of Cellular Mechanosensing / Rumi De, Assaf Zemel, Samuel A. Safran -- Section B. Impact of Nuclear Mechanics on Function -- Chapter 8. Mechanical Induction of Gene Expression in Connective Tissue Cells / Matthew W.C. Chan, Boris Hinz, Christopher A. McCulloch -- Chapter 9. Physical Plasticity of the Nucleus and its Manipulation / Irena Ivanovska, Joe Swift, Takamasa Harada, J. David Pajerowski, Dennis E. Discher -- Chapter 10. Prestressed Nuclear Organization in Living Cells / Aprotim Mazumder, T. Roopa, Abhishek Kumar, K. Venkatesan Iyer, Nisha M. Ramdas, G.V. Shivashankar -- Chapter 11. Nanotopography/Mechanical Induction of Stem-Cell Differentiation / Benjamin Kim Kiat Teo, Soneela Ankam, Lesley Y. Chan, Evelyn K.F. Yim -- Chapter 12. Mechanical Induction in Embryonic Development and Tumor Growth: Integrative Cues Through Molecular to Multicellular Interplay and Evolutionary Perspectives / Maria-Elena Fernandez-Sanchez, Fanny Serman, Padra Ahmadi, Emmanuel Farge -- Chapter 13. Informatics-Based Analysis of Mechanosignaling in the Laminopathies / Frank P.L. Lai, Radfidah A. Mutalif, Siew Cheng Phua, Colin L. Stewart -- Chapter 14. Autosomal Dominant Leukodystrophy Caused by Lamin B1 Duplications: A Clinical and Molecular Case Study of Altered Nuclear Function and Disease / Quasar Saleem Padiath, Ying-Hui Fu.
  • Volume 122 of Methods in Cell Biology describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (including mammalian cells, Xenopus, C. elegans, yeast). The volume enables investigators to analyze nuclear pore complex structure, assembly, and dynamics; to evaluate protein and RNA trafficking through the nuclear envelope; and to design in vivo or in vitro assays appropriate to their research needs.
  • Nuclear receptor superfamily 2009, Springer Protocols
    Nuclear receptors : one big family / Iain J. McEwan -- Methods for measuring ligand dissociation and nuclear receptor turnover in whole cells / Elizabeth M. Wilson -- Flow cytometry as a tool for measurement of steroid hormone receptor protein expression in leukocytes / Cherie L. Butts and Esther M. Sternberg -- X-ray crystallography of agonis/antagonist-bound receptors / Ashley C.W. Pike -- FRAP and FRET methods to study nuclear receptors in living cells / Martin E. van Royen ... [et al.] -- Receptor-DNA interactions : EMSA and footprinting / Jason T. Read ... [et al.] -- Chromatin immunoprecipitation (ChIP) methodology and readouts / Charles E. Massie and Ian G. Mills -- Yeast-based reporter assays for the functional characterization of cochaperone interactions with steroid hormone receptors / Heather A. Balsiger and Marc B. Cox -- High throughput analysis of nuclear receptor-cofactor interactions / Michael L. Goodson, Behnom Farboud, and Martin L. Privalsky -- Binding affinity and kinetic analysis of nuclear receptor/co-regulator interactions using surface plasmon resonance / Derek N. Lavery -- Using RNA interference to study protein function / Carol D. Curtis and Ann M. Nardulli -- Using intrinsic fluorescence emission spectroscopy to study steroid receptor and coactivator protein conformation dynamics / Kate Watt and Iain J. McEwan -- Development of phosphorylation site-specific antibodies to nuclear receptors / Inés Pineda Torra ... [et al.] -- Tissue-selective knockouts of steroid receptors : a novel paradigm in the study of steroid action / Karel De Gendt and Guido Verhoeven -- Methods for identifying and studying genetic alterations in hormone-dependent cancers / Outi R. Saramäki, Kati K. Waltering, and Tapio Visakorpi.
  • Nuclear receptors 2010, Springer
    Nuclear receptors an introductory overview / C.M. Bunce and M.J. Campbell -- What does evolution teach us about nuclear receptors? / G. Markov, F. Bonneton and V. Laudet -- Functions of nuclear receptors in insect development / D. Martín -- The glucocorticoid receptor / R.H. Oakley and J.A. Cidlowski -- Estrogen receptors: Their actions and functional roles in health and disease / S. Nilsson and J.-Å. Gustafsson -- Androgen receptor / J.T. Dalton and W. Gao -- Thyroid hormone receptors / B. Vennström, H. Liu and D. Forrest -- The vitamin D receptor (NR1I1) / O. Maguire and M.J. Campbell -- Retinoic acid receptors / A. Cras, F. Guidez and C. Chomienne -- PPARs: Important regulators in metabolism and inflammation / L.M. Sanderson and S. Kersten -- Xenobiotic receptors CAR and PXR / C. Klaassen and H. Lu -- Fxr / Y. Wang ... [et al.] -- Physiological functions of TR2 and TR4 orphan nuclear receptor / S. Liu ... [et al.] -- Nuclear receptors and ATP dependent chromatin remodeling: A complex story / C.J. Burd and T.K. Archer -- Non-genomic action of sex steroid hormones / A. Migliaccio, G. Castoria and F. Auricchio -- Ligand regulation and nuclear receptor action / M. Hewison -- New insights to nuclear receptor gene regulation from analysis of their response elements in target genes / C. Carlberg -- Systems biology: Towards realistic and useful models of molecular networks / F.J. Bruggeman ... [et al.].
  • Nuclear reprogramming 2005, Springer Protocols
    Nuclear transplantation in Xenopus / John B. Gurdon -- Nuclear transfer in sheep / William A. Ritchie -- Protocols for nuclear transfer in mice / Shaorong Gao -- Isolation of stromal stem cells from human adipose tissue / Andrew C. Boquest ... [et al.] -- Nuclear reprogramming by cell fusion / Robert H. Broyles ... [et al.] -- Polyethylene glycol-mediated cell fusion / Jian Yang and Ming Hong Shen -- Epigenetic reprogramming of somatic genomes by electrofusion with embryonic stem cells / Masako Tada and Takashi Tada -- Quantification of cell fusion by flow cytometry / Stephen Sullivan ... [et al.] -- Modulation of cell fate using nuclear and cytoplasmic extracts / Anne-Mari Håkelien, Kristine G. Gaustad, and Philippe Collas -- Transgenic systems in nuclear reprogramming / Megan Munsie, Peter Mountford, and Jennifer Nichols -- Using immunofluorescence to observe methylation changes in mammalian preimplantation embryos / Fátima Santos and Wendy Dean -- Observing S-phase dynamics of histone modifications with fluorescently labeled antibodies / Rong Wu, Anna V. Terry, and David M. Gilbert -- Quantitative analysis of telomerase activity and telomere length in domestic animal clones / Dean H. Betts ... [et al.] --Pluripotency: capacity for in vitro differentiation of undifferentiated embryonic stem cells / Cornelia Wiese ... [et al.] -- Staining embryonic stem cells using monoclonal antibodies to stage-specific embryonic antigens / Bruce A. Fenderson ... [et al.] -- Analysis of the nucleolar compartment of the nucleus as an indicator of nuclear reprogramming after nuclear transfer / Jacques-E. Fléchon -- Methylation-sensitive polymerase chain reaction / Hannah R. Moore, Richard R. Meehan, and Lorraine E. Young -- Analysis of DNA methylation profiles in preimplantation embryos using bisulfite mutagenesis / Yong-Mahn Han, Seok-Ho Kim, and Yong-Kook Kang -- Chromatin immunoprecipitation assay for mammalian tissues / Fiona B. Turner, Wang L. Cheung, and Peter Cheung -- Histone modifications and transcription factor binding on chromatin: ChIP/PCR assays / Jaejoon Won and Tae Kook Kim -- In vivo genomic footprinting using LM-PCR methods / Hiromi Tagoh, Peter N. Cockerill, and Constanze Bonifer -- Analyzing histone modification using crosslinked chromatin treated with micrococcal nuclease / Pascal Lefevre and Constanze Bonifer.
  • Nuclear transfer protocols 2006, Springer Protocols
    Cloning of exotic/endangered species: (desert bighorn sheep) / James "Buck" Williams ... [et al.] -- Handmade somatic cell cloning in cattle / Gábor Vatja, Ian M. Lewis, and R. Tayfur Tecirlioglu -- Genetic modification of sheep by nuclear transfer with gene-targeted somatic cells / A. John Clark, Sarah Burl, and Chris Denning -- Transgenesis using nuclear transfer in goats / Anthoula Lazaris ... [et al.] -- Nuclear reprogramming : an overview / Takashi Tada -- Expression of imprinted genes in cloned mice / Takashi Kohda, Fumitoshi Ishino, and Atsuo Ogura -- Nuclear remodeling assay in xenopus egg extract / Koichi Gonda and Nobuaki Kikyo -- In vitro reprogramming of nuclei and cells / Anne-Mari Håkelien ... [et al.] -- Techniques for nuclear transfer to mouse embryonic stem cells / Danielè Pralong and Paul J. Verma -- Gene expression and methylation patterns in cloned embryos / Christine Wrenzycki ... [et al.] -- Are there any normal clones? / Ian Wilmut -- Future and applications of cloning / Alan O. Trounson.Origin and progress of nuclear transfer in nonmammalian animals / Marie A. Di Berardino -- In vitro maturation and embryo production in cattle / Marc-André Sirard and Karine Coenen -- Activation of oocytes after nuclear transfer / Zoltán Macháty -- Culture medium preferences of pre-implantation cloned mouse embryos / Björn Heindryckx, Josiane Van der Elst, and Marc Dhont -- Maintenance of pregnancy in pigs with limited viable embryos / Tim King and Paul A. De Sousa -- Health and neonatal care of bovine clones / Jacqui T. Forsyth and David N. Wells -- Optimization of procedures for cloning by somatic cell nuclear transfer in mice / Young Gie Chung, Shaorong Gao, and Keith E. Latham -- Production of cloned calves using roscovitine-treated adult somatic cells as donors / Kazuchika Miyoshi, Sezen Arat, and Steven L. Stice -- A double nuclear transfer technique for cloning pigs / Irina A. Polejaeva, Shawn Walker, and Keith Campbell -- Nuclear transfer in nonhuman primates / Shoukhrat M. Mitalipov and Don P. Wolf --
  • Nucleolus 2011, Springer
  • Fertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation strategies should be based on the sound scientific knowledge and principles. One of the main objectives of fertility preservation in females is prevention of oocyte depletion. The mechanisms of oocyte loss and survival in the ovary are complex, which include genetic control both in germ cells and in somatic cells, DNA damage and repair mechanism, apoptosis and autophagy, and other poorly understood molecular mechanisms.To develop clinically effective and safe strategies for fertility preservation, it is essential to know and understand the fundamentals of oocyte and ovarian biology at the molecular level. Thus, the purpose of this edition is to review the current progress in research related to molecular and genetic control of oocyte development that can be applied to fertility preservation. The main topics that are discussed in this publication include molecular signaling mechanisms of oocyte activation and loss, genomic integrity of oocytes, and epigenetics.
  • Oogenesis 2013, Springer
    The oocyte is the largest and most mysterious cell in the body of mammalian organisms. Through its growth and maturation, it reaches extreme levels of specialization, while maintaining at the same time a condition of totipotency. Its unique ability, in co-operation with the spermatozoon, to give rise to a fully developed organism formed from hundreds of different tissues and myriads of individual cells has inspired intellectuals of all ages.Oogenesis finds impetus and purpose in casting scientific perspective towards this unique cell for the benefit of scientists and assisted reproductive technology (ART) specialists. The authors of the chapters are distinguished authorities in their respective areas of competence. From the opening of the book the reader is lead on a fantastic voyage from the formation of the primordial oocyte to the development of the early embryo, passing through crucial processes of oogenesis, such as co-ordination of oocyte and follicle growth, gene expression and organelle reorganization during growth and maturation, epigenetic mechanisms, regulation of meiosis, totipotency, cell polarity, oogenesis in vitro and maternal regulation of early development.
  • Fundamentals of optical microscopy / Franco Quercioli -- The white confocal: continuous spectral tuning in excitation and emission / Rolf Borlinghaus -- Second/third harmonic generation microscopy / Shakil Rehman ... [et al.] -- Role of scattering and nonlinear effects in the illumination and the photobleaching distribution profiles / Zeno Lavagnino, Francesca Cella Zanacchi and Alberto Diaspro -- New analytical tools for evaluation of spherical aberration in optical microscopy / Isabel Escobar ... [et al.] -- Improving image formation by pushing the signal-to-noise ratio / Emiliano Ronzitti ... [et al.] -- Site-specific labeling of proteins in living cells using synthetic fluorescent dyes / Gertrude Bunt -- Imaging molecular physiology in cells using FRET-based fluorescent nanosensors / Fred S. Wouters -- Measuring molecular dynamics by FRAP, FCS, and SPT / Kevin Braeckmans ... [et al.] -- In vitro-in vivo fluctuation spectroscopies / M. Collini ... [et al.] -- Interference x-ray diffraction from single muscle cells reveals the molecular basis of muscle braking / L. Fusi ... [et al.] -- Low concentration protein detection using novel SERS devices / Gobind Das ... [et al.] -- Near infrared three-dimensional nonlinear optical monitoring of stem cell differentiation / Uday K. Tirlapur and Clarence Yapp -- A correlative microscopy: a combination of light and electron microscopy / Umberto Fascio and Anna Sartori-Rupp.
  • Oral cytology 2013, Springer
  • Osmosensing and osmosignaling 2007, ScienceDirect
    Water compartments in cells / G. D. Fullerton ... [et al.] -- Yeast osmoregulation / S. Hohmann ... [et al.] -- Physiological analysis of bacterial mechanosensitive channels / I. R. Booth ... [et al.] -- Control of cell cycle in response to osmostress: Lessons from yeast / J. Clotet ... [et al.] -- Bacterial osmosensing transporters / J. M. Wood -- Plant gene networks in osmotic stress response: From genes to regulatory networks / L. S. Tran ... [et al.] -- Osmosensing by integrins in rat liver / F. Schliess ... [et al.] -- Hyperosmotic activation of the CD95 system / R. Reinehr ... [et al.] -- New approaches for determining apoptotic volume decrease in cells / C. D. Bortner ... [et al.] -- Transient receptor potential channels in mechanosensing and cell volume regulation / S. F. Pedersen ... [et al.] -- Cell volume regulatory ion channels in cell proliferation and cell death / F. Lang ... [et al.] -- Actin cytoskeleton architecture and signaling in osmosensing / E. A. Papakonstanti ... [et al.] -- Osmotic stress and DNA damage / N. I. Dmitrieva ... [et al.] -- Transcriptional activator tone-binding protein in cellular protection and differentiation / J. A. Kim ... [et al.] -- Desiccation response of mammalian cells: Anhydrosignaling / Z. Huang ... [et al.] -- Tonicity-regulated gene expression / J. D. Ferraris ... [et al.] -- Hyperosmotic induction of mitogen-activated protein kinase scaffolding / T. L. Hilder ... [et al.] -- Osmoregulation of bile formation / R. Kubitz ... [et al.] -- Osmosignaling and volume regulation in intestinal epithelial cells / C. H. Lim ... [et al.] -- Osmotic regulation of cellular glucose uptake / P. Gual ... [et al.] -- Effects of osmolytes on protein folding and aggregation in cells / Z. Ignatova ... [et al.] -- Simulations of macromolecules in protective and denaturing osmolytes: Properties of mixed solvent systems and their effects on water and protein structure and dynamics / D. A. Beck ... [et al.] -- Application of the transfer model to understand how naturally occurring osmolytes affect protein stability / M. Auton ... [et al.] -- Mechanisms of high salinity tolerance in plants / N. Tuteja -- Phenotype of the taurine transporter knockout mouse / U. Warskulat ... [et al.] -- Molecular basis of osmolyte effects on protein and metabolites / J. Rosgen -- Methods of changing biopolymer volume fraction and cytoplasmic solute concentrations for in vivo biophysical studies / M. C. Konopka ... [et al.] -- Characterization of plant aquaporins / R. Kaldenhoff ... [et al.].
  • Pancreatic stem cells 2009, Springer
  • Peroxiredoxin systems 2007, Springer
    Introduction / Leopold Flohé and J. Robin Harris -- Evolution of the peroxiredoxins / Bernard Knoops, Eléonore Loumaye and Valérie Van Der Eecken -- Structural survey of the peroxiredoxins / P. Andrew Karplus and Andrea Hall -- The catalytic mechanism of peroxiredoxins / Leslie B. Poole -- Kinetics of peroxiredoxins and their role in the decomposition of peroxynitrite / Madia Trujillo ... [et al.] -- The peroxiredoxin repair proteins / Thomas J. Jönsson and W. Todd Lowther -- Peroxiredoxins in bacterial antioxidant defense / James M. Dubbs and Skorn Mongkolsuk -- The NADH oxidase-Prx system in Amphibacillus xylanus / Youichi Niimura -- Peroxiredoxin systems in mycobacteria / Timo Jaeger -- Peroxiredoxin systems of protozoal parasites / Marcel Deponte, Stefan Rahlfs and Katja Becker -- The trypanothione system / Luise R. Krauth-Siegel, Marcelo A. Comini and Tanja Schlecker -- Functions of typical 2-Cys peroxiredoxins in yeast / Brian A. Morgan and Elizabeth A. Veal -- The dual function of plant peroxiredoxins in antioxidant defence and redox signaling / Karl-Josef Dietz -- Mitochondrial peroxiredoxins / Zhenbo Cao, J. Gordon Lindsay and Neil W. Isaacs -- Peroxiredoxins in the lung with emphasis on peroxiredoxin VI / Bruno Schremmer ... [et al.] -- Peroxiredoxins in gametogenesis and embryo development / Isabelle Donnay and Bernard Knoops -- Peroxiredoxins in the central nervous system / Fumiyuki Hattori and Shinzo Oikawa -- Stress-induced peroxiredoxins / Tetsuro Ishii and Toru Yanagawa.
  • Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. In recent years it has become increasingly clear that peroxisomes are involved in a range of important cellular functions in almost all eukaryotic cells. In higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid alpha-oxidation, glyoxylate detoxification, etc, and in humans peroxisomes are associated with several important genetic diseases.
  • Phospholipases generate lipid signaling molecules through their hydrolytic action on phospholipids and are known to regulate function of a variety of cells under normal and diseased conditions. While several physiological, biochemical and molecular techniques have identified key players involved in different disease processes, phospholipases have also emerged as critical players in the pathogenesis of a number of different diseases including cancer and heart disease. In addition, phospholipases are also implicated in such conditions as brain disorder/injury, kidney and immune cell dysfunction. Phospholipases in Health and Disease is a compilation of review articles dedicated to the study of the field with respect to biochemical and molecular mechanisms of normal and abnormal cell function. The wide range of area covered here is of interest to basic research scientists, clinicians and graduate students, who are engaged in studying pathophysiological basis of a variety of diseases. Furthermore, this book highlights the potential of the different phospholipases as therapeutic targets as well as part of prevention strategies. Twenty three articles in this book are organized in four sections that are designed to emphasize the most characterized forms of the phospholipases in mammalian cells. The first section discusses general aspect of phospholipases. Section two covers the role and function of phospholipase A in different pathophysiological conditions. The third section is focussed on phospholipase C which is believed to play a central role in transmembrane signaling. The final section covers phospholipase D which is present in a variety of different cells. The book illustrates that the activation of phospholipases is of fundamental importance in signal transduction affecting cell function. Overall, this book discusses the diverse mechanisms of phospholipase mediated signal transduction in different pathophysiological conditions and raises the possibility of specific forms of phospholipases serving as novel targets for drug development.
  • Plant cell culture protocols. 2nd ed. 2005, Springer Protocols
  • Podocytopathy 2014, Karger
    Cell biology of the podocyte / Jefferson, J.A.; Shankland, S.J. -- Cell cycle and podocyte injury / Hagmann, H.H.; Shankland, S.J.; Brinkkoetter, P.T. -- The podocyte cytoskeleton : key to a functioning glomerulus in health and disease / Faul, C. -- Crosstalk between podocytes and tubular epithelial cells / Leung, J.C.K.; Kar, N.L.; Tang, S.C.W. -- Role of mitochondria in podocyte injury / Yuan, Y.; Huang, S.; Zhang, A. -- Autophagy in podocytes / Zhang, L.; Livingston, M.J.; Chen, J.-K.; Dong, Z. -- PPAR- : signaling in podocyte injury / Wang, W.; Yang, T. -- Podocyte injury in FSGS / Ding, W.Y.; Saleem, M.A. -- Circulating soluble urokinase receptor and focal segmental glomerulosclerosis / Wei, C.; Reiser, J. -- Anti-phospholipase A2 receptor-1 autoantibodies and membranous nephropathy / Beck, L.H. -- Anti-neutral endopeptidase antibodies, autoantibodies, anti-bovine serum albumin antibodies and membranous nephropathy / Ronco, P.; Debiec, H. -- Podocytopathy in diabetes : a metabolic disorder / Merscher, S.; Lenz, O.; Fornoni, A. -- Obesity-related glomerulopathy and podocyte injury / Camici, M. -- Podocyte injury in HIV-associated nephropathy / Mallipattu, S.K.; He, J.C. -- Retinoic acid : a potential pharmacologic approach in the treatment of podocytopathy / Sharma, S.; Mallipattu, S.K.; Zhong, Y.; He, J.C. -- Immunomodulatory drugs and the podocyte / Mathieson, P.W. -- Triptolide protects podocytes from injury / Qin, W.; Liu, Z.-H. -- Fly : a model to study the podocyte / Na, J.; Cagan, R.L. -- Zebrafish models of podocytopathies / Boucher, R.C.; Zhou, W. -- The role of micrornas in podocytes / Shi, S.; Liu, Z.-H. -- An integrative biology approach to study podocyte function / Ju, W.; Hodgin, J.; Jiang, S.; Kretzler, M.
  • Polyamine cell signaling 2006, Springer
    Polyamine structure and synthetic analogs / Patrick M. Woster -- Acute increases in intracellular putrescine lead to the increase in steady-state levels of c-fos, c-jun, RING3, and Id-1 mRNAs / Allan A. Ancheta, Leo Hawel III, and Craig V. Byus -- Polyamine-dependent early cellular signals and cell proliferation / Stina M. Oredsson -- Cellular signals mediating growth arrest after polyamine depletion / Jian-Ying Wang -- Role of polyamines in the regulation of chromatin acetylation / Cheryl A. Hobbs and Susan K. Gilmour -- Role of polyamines in regulation of sequence-specific DNA binding activity / Sripriya Venkiteswaran, Thresia Thomas, and T.J. Thomas -- Polyamine metabolism and the hypertrophic heart / Lisa M. Shantz and Emanuele Giordano -- Influence of polyamines on breast cancer biology / Andrea Manni -- Polyamines in regulation of prostatic cell growth / Raymond G. Schipper ... [et al.] --Polyamines and cytoskeletal regulation during intestinal epithelial restitution / Ramesh M. Ray and Leonard R. Johnson -- Regulation of Kv channel activity and intercellular junctions by polyamines in intestinal epithelial cells / Jaladanki N. Rao and Jian-Ying Wang -- Polyamine block of Kir channels: toward a molecular picture / Harley T. Kurata and Colin G. Nichols -- Regulation of ornithine decarboxylase expression / Lo Persson -- Evidence for a multistep model for eukaryotic polyamine transport / Richard Poulin ... [et al.] -- Bacterial and eukaryotic transport systems / Kazuei Igarashi and Keiko Kashiwagi -- Regulation of S-adenosylmethionine decarboxylase / Colin Hanfrey -- Genetic engineering of polyamine catabolism in transgenic mice and rats / Juhani Jänne ... [et al.].Polyamines in kidney biology / Joseph Satriano -- Polyamines in pulmonary vascular biology / Jack W. Olson and Mark N. Gillespie -- Recent advances in the understanding of mammalian polyamine catabolism: the regulation and potential role of polyamine catabolism in drug response and disease processes / Robert A. Casero, Jr. ... [et al.] -- Cellular signaling and polyamines in the control of apoptosis in intestinal epithelial cells / Leonard R. Johnson and Ramesh M. Ray -- The role of ornithine decarboxylase in Myc-induced tumorigenesis / Jonas A. Nilsson and John L. Cleveland -- Protective effect of polyamines on NSAID-induced injury and apoptosis / Heather M. Wallace and Alun Hughes -- Role of polyamines in the control of the immune response in the brain / Denis Soulet and Serge Rivest -- Implication of polyamines in apoptosis of immunoresponse cells / Rupesh Chaturvedi and Keith T. Wilson -- Polyamines and cancer / Ajit K. Verma -- Polyamine pools and cancer prevention / Eugene W. Gerner and David E. Stringer --
  • Polyextremophiles 2013, Springer
    Introduction / Joseph Seckbach, Aharon Oren, and Helga Stan-Lotter -- Foreword / Richard W. Castenholz -- Preface / Koki Horikoshi -- Editors' biographies -- List of authors and their addresses -- Polyextremophiles and the constraints for terrestrial habitability / M.C. Capece et al. -- Life on the edge and astrobiology : who is who in the polyextremophiles world? / J. Seckbach -- The dynamic genomes of acidophiles / F.J. López de Saro et al. -- Two centuries of microbiological research in the Wadi Natrun, Egypt : a model system for the study of the ecology, physiology, and taxonomy of haloalkaliphilic microorganisms / A. Oren -- Adaptation in haloalkaliphiles and natronophilic bacteria / H.L. Banciu and D.Y. Sorokin -- A random biogeochemical walk into three soda lakes of the western USA : with an introduction to a few of their microbial denizens / R.S. Oremland -- Halophilic, acidophilic, and haloacidophilic prokaryotes / H. Minegishi -- Life in magnesium- and calcium-rich hypersaline environments : salt stress by chaotropic ions / A. Oren -- Survival strategies of halophilic oligotrophic and desiccation resistant prokaryotes / H. Stan-Lotter and S. Fendrihan -- Radiation resistance in extremophiles : fending off multiple attacks / K.M. Webb and J. DiRuggiero -- Thermoalkaliphilic microbes / V. Kumar and T. Satyanarayana -- Acido- and thermophilic microorganisms : their features, and the identification of novel enzymes or pathways / Y. Kawarabayasi -- Microbial diversity in acidic high-temperature steam vents / R.L. Weiss Bizzoco and S.T. Kelley -- Left out in the cold : life in cryoenvironments / J. Goordial et al. -- Microbial diversity and enzymes in ikaite columns : a cold and alkaline environment in Greenland / J.K. Vester et al. -- Microbial communities thriving in various ice ecosystems / B. Sattler et al. -- Snow algae : adaptation strategies to survive on snow and ice / T. Leya -- Adaptation of Antarctic freshwater green algae to extreme environments / H. Hu -- Deep subsurface oil reservoirs as poly-extreme habitats for microbial life. A current review / A. Wentzel et al. -- Expanding limits for life to a new dimension : microbial growth at hypergravity / S. Deguchi and K. Horikoshi -- Microbial eukaryotes in marine oxygen minimum zones / W.D. Orsi and V.P. Edgcomb -- Deep hypersaline anoxic basins as model systems for environmental selection of microbial plankton / A. Stock et al. -- Microbial eukaryotes in hypersaline anoxic deep-sea basins / V.P. Edgcomb and W.D. Orsi -- Life at high salt and low oxygen : how do the Halobacteriaceae cope with low oxygen concentrations in their environment? / A. Oren -- Niches and adaptations of polyextremotolerant black fungi / M. Grube et al. -- Polyextremophilic photoautotrophic eukaryotic algae / W. Reisser -- Extremophilic magnetotactic bacteria / C.T. Lefèvre and D.A. Bazylinski -- Tardigrades : an example of multicellular extremophiles / D. Schulze-Makuch and J. Seckbach -- Polyextremophiles : summary and conclusions / J. Chela-Flores.
  • Potassium channels 2008, Springer Protocols
    Identifying transcriptional regulatory regions using reporter genes and DNA-protein interactions by chromatin immunoprecipitation / Lezanne Ooi and Ian C. Wood -- Quantitative RT-PCR methods for investigation of low copy potassium channel gene expresssion in native murine arteries / Alex Cheong, Samuel J. Fountain, and David J. Beech -- Cloning of potassium chanel splice variants from tissues and cells / Lie Chen and Michael J. Shipston -- Chemiluminescence assays to investigate membrane expression and clathrin-mediated endocytosis of KATP channels / Andrew J. Smith and Asipu Sivaprasadarao -- Investigation of KATP channel endocytosis by immunofluorescence / Andrew J. Smith and Asipu Sivaprasadarao -- Investigation of KATP channel endocytosis and cell surface density by biotinylation and western blotting / Andrew J. Smith and Asipu Sivaprasadarao -- Lipid microdomains and K+ channel compartmentation : detergent and non-detergent-based methods for the isolation and characterisation of cholesterol-enriched lipid rafts / Laura J. Sampson and Caroline Dart -- Determination of phosphoinositide binding to K+ channel subunits using a protein-lipid overlay assay / Alison M. Thomas and Andrew Tinker -- Protein complex analysis of native brain potassium channels by proteomics / Guillaume Sandoz and Florian Lesage -- Xenopus oocytes as a heterologous expression system for studying ion channels with the patch-clamp technique / Paolo Tammaro, Kenju Shimomura, and Peter Proks -- Whole-cell recording using the perforated patch clamp technique / Jonathan D. Lippiat -- Recording the activity of ATP-sensitive K+ channels in open-cell cell-attached configuration / Andrei I. Tarasov -- Planar patch clamp : advances in electrophysiology / Andrea Brüggemann ... [et al.] -- Analysing steroid modulation of BKCa channels reconstituted into planar lipid bilayers / Heidi de Wet, Jonathan D. Lippiat, and Marcus Allen -- Using bioluminescence resonance energy transfer to measure ion channel assembly / Gina M. Whitaker and Eric A. Accili -- The use of FRET microscopy to elucidate steady state channel conformational rearrangements and G protein interaction with the GIRK channels / Adi Raveh, Inbal Riven, and Eitan Reuveny -- The voltage-clamp fluorometry technique / Chris S. Gandhi and Riccardo Olcese -- Identification of mutations in the Kir6.2 subunit of the KATP channel / Sarah E. Flanagan and Sian Ellard -- Modulation of potassium ion channel proteins utilising antibodies / Mark L. Dallas, Susan A. Deuchars, and Jim Deuchars -- Fluorescence-based Tl+-influx assays as a novel approach for characterization of small-conductance CA²⁺-activated K+ channel modulators / Susanne Jørgensen, Tina H. Johansen, and Tino Dyhring -- Rubidium efflux as a tool for the pharmacological characterisation of compounds with BK channel opening properties / Neil G. McKay, Robert W. Kirby, and Kim Lawson -- Recording hERG potassium currents and assessing the effects of compounds using the whole-cell patch-clamp technique / Ray M. Helliwell.
  • Primary cilia 2009, ScienceDirect
  • Cell death : history and future / Zahra Zakeri and Richard A. Lockshin -- Caspase mechanisms / Guy S. Salvesen and Stefan J. Riedl -- The mitochondrial death pathway / Anas Chalah and Roya Khosravi-Far -- Apoptotic pathways in tumor progression and therapy / Armelle Melet ... [et al.] -- Therapeutic targeting of death pathways in cancer : mechanisms for activating cell death in cancer cells / Ting-Ting Tan and Eileen White -- Overcoming resistance to apoptosis in cnacer therapy / Peter Hersey, Xu Dong Zhang, and Nizar Mhaidat -- Trail receptors : targets for cancer therapy / Robin C. Humphreys and Wendy Halpern -- Rational design of therapeutics targeting the BCL-2 family : are some cancer cells primed for death but waiting for a final push? / Victoria Del Gaizo Moore and Anthony Letai -- Autophagy and tumor suppression : recent advancesin understanding the link between autophagic cell death pathways and tumor development / Shani Bialik and Adi Kimchi -- Regulation of programmed cell death by the P53 pathway / Kageaki Kuribayashi and Wafik S. El-Deiry -- Regulation of programmed cell death by NF-[kappa]B and its role in tumorigenesis and therapy / Yongjun Fan ... [et al.] -- Targeting proteasomes as therapy in multiple myeloma / Dharminer Chauhan, Teru Hideshima, and Kenneth C. Anderson -- Histone deacetylase inhibitors : mechanisms and clinical significance in cancer : HDAC inhibitor-induced apoptosis / Sharmila Shankar and Rakesh K. Srivastava -- RNA interference and cancer : endogenous pathways and therapeutic approaches / Derek M. Dykxhoorn, Dipanjan Chowdhury, and Judy Lieberman -- Cancer stem cells and impaired apoptosis / Zainab Jagani and Roya Khosravi-Far.
  • The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed the experimental landscape and opened new possibilities. The advances in PSC have provided an important tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled environment. For example, reprogramming cells from patients with neurological diseases allows the study of molecular pathways particular to specific subtypes of neurons such as dopaminergic neurons in Parkinson.s Disease, Motor neurons for Amyolateral Sclerosis or myelin for Multiple Sclerosis. In addition, because PSC technology allows for the study of human neurons during development, disease-specific pathways can be investigated prior to and during disease onset. Detecting disease-specific molecular signatures in live human brain cells, opens possibilities for early intervention therapies and new diagnostic tools. Importantly, it is now feasible to obtain gene expression profiles from neurons that capture the genetic uniqueness of each patient. Importantly, once the neurological neural phenotype is detected in vitro, the so-called "disease-in-a-dish" approach allows for the screening of drugs that can ameliorate the disease-specific phenotype. New therapeutic drugs could either act on generalized pathways in all patients or be patient-specific and used in a personalized medicine approach. However, there are a number of pressing issues that need to be addressed and resolved before PSC technology can be extensively used for clinically relevant modeling of neurological diseases.
  • Part I. Cell Wall Polymers and Structures of Bacteria -- 1. The Murein Sacculus / Silke Litzinger and Christoph Mayer -- 2. Occurrence, Structure, Chemistry, Genetics, Morphogenesis, and Functions of S-Layers / Paul Messner, Christina Schäffer, Eva-Maria Egelseer, and Uwe B. Sleytr -- 3. Bacterial Polysaccharide Capsules / David Corbett, Thomas Hudson, and Ian S. Roberts -- 4. Lipopolysaccharides / Alba Silipo, Cristina De Castro, Rosa Lanzetta, Michelangelo Parrilli, and Antonio Molinaro -- 5. Structure, Biosynthesis, and Function of Teichoic Acids and Related Cell Wall Glycopolymers in the Gram-positive Cell Envelope / Maren Rautenberg, Thomas Kohler, Guoqing Xia, Emir Kulauzovic, and Andreas Peschel -- 6. Outer Membrane Proteins / Oliver Mirus, Alexander Hahn, and Enrico Schleiff -- Part II. Cell Wall Polymers and Structures of Archaea -- 7. Cell Envelopes of Methanogens / Harald Claus and Helmut König -- 8. The Cell Envelopes of Haloarchaea: Staying in Shape in a World of Salt / Jerry Eichler, Mehtap Abu-Qarn, Zvia Konrad, Hilla Magidovich, Noa Plavner, and Sophie Yurist-Doutsch -- 9. Cell Envelopes of Crenarchaeota and Nanoarchaeota / Reinhard Rachel -- Part III. Biological Activities -- 10. Immunochemistry of the Cell Walls of Methanogenic Archaea: A View from the Past into the Future / Everly Conway de Macario and Alberto J.L. Macario -- 11. Cell Wall Structure and Pathogenicity / T.A. Oelschlaeger, U. Dobrindt, and J. Hacker -- Part IV. Cell Wall Growth and Inhibition -- 12. Cell Wall Targeted Antibiotics / Regine Hakenbeck, Reinhold Brückner, and Bernhard Henrich -- 13. Bacterial Autolysins / Marie-Pierre Chapot-Chartier -- Part V. Cell Wall Interactions -- 14. Prokaryotic Cell-Cell Interaction / Reinhard Wirth -- 15. Adhesion of Bacteria to Protists / Renate Radek -- Part VI. Application of Cell Wall Components -- 16. Prokaryotic Cell Wall Components: Structure and Biochemistry / Uwe B. Sleytr, Eva-Maria Egelseer, Nicola Ilk, Paul Messner, Christina Schäffer, Dietmar Pum, and Bernhard Schuster -- 17. Accumulation of Heavy Metals by Micro-organisms: Biomineralization and Nanocluster Formation / Sonja Selenska-Pobell and Mohamed Merroun.
  • Prominin-1 (CD133) 2013, Springer
  • In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases.
  • Proteins 2010, Springer
    Energetics of peptide and protein binding to lipid membranes / William C. Wimley -- Membrane association and pore formation by alpha-helical peptides / Burkhard Bechinger -- Role of membrane lipids for the activity of pore forming peptides and proteins / Gustavo Fuertes ... [et al.] -- Cholesterol-dependent cytolysins / Robert J.C. Gilbert -- Laetiporus sulphureus lectin and aerolysin protein family / Jose Miguel Manchero .. [et al.] -- Interfacial interactions of pore-forming colicins / Helen Ridley, Christopher L. Johnson and Jeremy H. Lakey -- Permeabilization of the outer mitochondrial membrane by BCL-2 proteins / Ana J. Garcia-Suez ... [et al.] -- Molecular mechanism of sphingomyelin : specific membrane binding and pore formation by actinoporins / Biserka Bakra and Gregor Anderluh --Hemolysin E (hlye, clya, shea) and related toxins / Stuart Hunt, Jeffrey Green and Peter J. Artymiuk -- Pore formation by cry toxins / Mario Soberin ... [et al.] -- Role of heparan sulfates and glycosphingolipids in the pore formation of basic polypeptides of cobra cardiotoxin / Wen-guey Wu ... [et al.] -- Amyloid peptide pores and the beta sheet conformation / Bruce L. Kagan and Jyothi Thundimadathil.
  • Proteus effect 2004, NAP
    Plant or animal? -- Mouse strain 129 -- The purple cell -- Mystery in a dish -- The embryo experiments -- The canary's song -- After the birth of Louise Brown -- Monkeys to humans -- Epic upon epic -- Marrow to brain? -- The art of cell replacement -- After tomorrow.
  • Neurosphere and Neural Colony-Forming Cell Assays / Sharon A. Louis, Brent A. Reynolds -- Directed Neuronal Differentiation of Embryonic and Adult-Derived Neurosphere Cells / Marcos R. Costa, Ravi Jagasia, Benedikt Berninger -- Culture and Differentiation of Human Neural Stem Cells / Soojung Shin, Mohan Vemuri -- Neural Differentiation of Human Embryonic Stem Cells / Mirella Dottori, Alice Pébay, Martin F. Pera -- Isolation and Culture of Primary Human CNS Neural Cells / Manon Blain, Veronique E. Miron, Caroline Lambert, Peter J. Darlington, Qiao-Ling Cui, Philippe Saikali, V. Wee Yong, Jack P. Antel -- Bioengineering Protocols for Neural Precursor Cell Expansion / Behnam A. Baghbaderani, Arindom Sen, Michael S. Kallos, Leo A. Behie -- Intracellular Calcium Assays in Dissociated Primary Cortical Neurons / Navjot Kaur, David V. Thompson, David Judd, David R. Piper, Richard G. Del Mastro -- Dissociated Hippocampal Cultures / Francine Nault, Paul Koninck -- Primary Sensory and Motor Neuron Cultures / Andrea M. Vincent, Eva L. Feldman -- Retinal Cell and Tissue Culture / Francisco L.A.F. Gomes, Michel Cayouette -- Preparation of Normal and Reactive Astrocyte Cultures / Jean Vellis, Cristina A. Ghiani, Ina B. Wanner, Ruth Cole -- Oligodendrocyte Progenitor Cell Culture / Akiko Nishiyama, Ryusuke Suzuki, Hao Zuo, Xiaoqin Zhu -- Isolation of Microglia Subpopulations / Makoto Sawada, Hiromi Suzuki -- Microglia from Progenitor Cells in Mouse Neopallium / Sergey Fedoroff, Arleen Richardson -- Primary Schwann Cell Cultures / Haesun A. Kim, Patrice Maurel -- Primary Dissociated Astrocyte and Neuron Co-culture / Shelley Jacobs, Laurie C. Doering -- Cerebellar Slice Cultures / Josef P. Kapfhammer -- Hippocampal Slice Cultures / Jesse E. Hanson, Adrienne L. Orr, Silvia Fernandez-Illescas, Ricardo A. Valenzuela, Daniel V. Madison -- Molecular Substrates for Growing Neurons in Culture / Saulius Satkauskas, Arnaud Muller, Morgane Roth, Dominique Bagnard -- Guidance and Outgrowth Assays for Embryonic Thalamic Axons / Alexandre Bonnin -- Detection of Cell Death in Neuronal Cultures / Sean P. Cregan -- Live Imaging of Neural Cell Functions / Sabine Bavamian, Eliana Scemes, Paolo Meda -- Tissue Culture Procedures and Tips / Arleen Richardson, Sergey Fedoroff.
  • Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays * Discusses many new assays developed since the previous edition. Presents recent developments in cytometric intrumentation/technology.
  • Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays. Discusses many new assays developed since the previous edition * Presents recent developments in cytometric intrumentation/technology.
  • Receptor-receptor interactions 2013, ScienceDirect
    This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes. With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come.
  • Red blood cell aggregation 2012, CRCnetBASE
  • Fulltext (pt. B) ScienceDirect
  • 1. Cell Therapy for Neurodegenerative Disorders / Ilyas Singec -- 2. New Prospects for Neural Stem Cell Therapies of Nervous System Diseases Toward the Establishment of Atypical Ectopic Perivascular Stem Cell Niches / Clara Alfaro-Cervello, Chiara Cossetti, Elena Giusto, Matteo Donegà and Stefano Pluchino -- 3. Cultured Limbal Epithelial Stem Cell Therapy for Ocular Surface Diseases / Hannah J. Levis, Julie T. Daniels and Sajjad Ahmad -- 4. Keratinocyte Stem Cells: Biology and Clinical Applications / Carlo Pincelli and Alessandra Marconi -- 5. Cardiac Regeneration with Stem Cells / Beatriz Pelacho, Manuel Mazo, Sheyla Montori, Ana Maria Simon-Yarza, Juan Jose Gavira, Maria J. Blanco-Prieto and Felipe Prósper -- 6. Development of Biological Approaches to Improve Muscle Healing After Injury and Disease / Jonathan D. Proto and Johnny Huard -- 7 Mesenchymal Stem Cells in Bone and Cartilage Regeneration / Mohamadreza Baghaban Eslaminejad, Elham Zomorodian and Fatemeh Bagheri -- 8. Pancreatic Reprogramming / Juan Domínguez-Bendala -- 9. Pancreatic Regeneration in the Face of Diabetes / Zeeshan Ahmad -- 10. Regenerative Therapies for Liver Diseases / Amar Deep Sharma, Ina Rittelmeyer, Tobias Cantz and Michael Ott -- 11. Clinical Studies of Cell Therapy for Liver Cirrhosis / James A. Thomas and Stuart J. Forbes -- 12. Stem Cell Applications for the Treatment of Gastrointestinal System Diseases / Jacobo Trebol Lopez, Tihomir Georgiev-Hristov, Mariano García-Arranz and Damián García-Olmo -- 13. Germ Line Stem Cells: A Promising Alternative Source for Stem-Cell-Based Therapies in Regenerative Medicine / Ellen Goossens and Herman Tournaye -- 14. Cord Blood Stem Cells and Regenerative Medicine / David T. Harris.
  • Reporter genes 2007, Springer Protocols
    Methodologies for staining and visualization of [beta]-galactosidase in mouse embryos and tissues / Siobhan Loughna and Deborah Henderson -- Immunohistochemical detection of [beta]-galactosidase or green fluorescent protein on tissue sections / Philip A. Seymour and Maike Sander -- Detection of reporter gene expression in murine airways / Maria Limberis, Peter Bell, and James M. Wilson -- Three-dimensional analysis of molecular signals with episcopic imaging techniques / Wolfgang J. Weninger and Timothy J. Mohun -- Fluorescent proteins for cell biology / George H. Patterson -- Detection of GFP during nervous system development in Drosophila melanogaster / Karin Edoff, James S. Dods, and Andrea H. Brand -- Autofluorescent proteins for flow cytometry / Charles G. Bailey and John E. J. Rasko -- Fluorescent protein reporter systems for single-cell measurements / Steven K. Dower, Eva E. Qwarnstrom, and Endre Kiss-Toth -- Subcellular imaging of cancer cells in live mice / Robert M. Hoffman -- Noninvasive imaging of molecular events with bioluminescent reporter genes in living subjects / Pritha Ray and Sanjiv Sam Gambhir -- Green fluorescent protein as a tracer in chimeric tissues : the power of vapor fixation / Harald Jockusch and Daniel Eberhard.
  • Ch. 1. DT40 gene disruptions: a how-to for the design and the construction of targeting vectors / Hiroshi Arakawa and Jean-Marie Buerstedde -- Ch. 2. Immunoglobulin gene conversion or hypermutation: That's the question / Jean-Marie Buerstedde and Hiroshi Arakawa -- Ch. 3. Genome resources for the DT40 community / Randolph B Caldwell and Andrzej M. Kierzek -- Ch. 4. Chromosome engineering in DT40 cells and mammalian centromere function / William R.A. Brown ... [et al.] -- Ch. 5. Function of recQ family helicase in genome stability / Masayuki Seki, Shusuke Tada and Takemi Enomoto -- Ch. 6. Genetic analysis of apoptotic execution / Sandrine Ruchaud ... [et al.] -- Ch. 7. The DT40 system as a tool for analyzing kinetochore assembly / Masahiro Okada, Tesuya Hori and Tatsuo Fukagawa -- Ch. 8. Analysing the DNA damage and replication checkpoints in DT40 cells / Michael D Rainey, George Zachos, and David AF Gillespie -- Ch. 9. Using DT40 to study clathrin function / Frank R. Wettey and Antony P. Jackson -- Ch. 10. Genetic analysis OF B cell signaling / Hisaaki Shinohara and Tomohiro Kurosaki --Ch. 11. DT40 mutants: a model to study transcriptional regulation of B cell development and function / Jukka Alinikula, Olli Lassila and Kalle-Pekka Nera -- Ch. 12. Transcription and RNA processing factors play complex roles IN DT40 cells / Stephanie Bush and James L. Manley -- Ch. 13. Participation of histones, histone modifying enzymes and histone chaperones in vertebrate cell functions / Hidehiko Kikuchi ... [et al.] -- Ch. 14. Analysis of gene expression, copy number and palindrome formation with a DT40 enriched cDNA Microarray / Paul E. Neima ... [et al.] -- Ch. 15. Analysis of DNA replication damage bypass and its role in immunoglobulin repertoire development / Julian E. Sale, Anna-Laura Ross and Laura J. Simpson -- Ch. 16. The fanconi anemia pathway promotes homologous recombination repair in DT40 cell line / Julian E. Sale, Anna-Laura Ross and Laura J. Simpson -- Ch. 17. Calcium signaling, ion channels and more / Anne-Laure Perraud, Carsten Schmitz, Andrew M. Scharenberg -- Ch. 18. Phenotypic analysis of cellular responses to DNA damage / Helfrid Hochegger and Shunichu Takeda -- Ch. 19. ATM, a paradigm for a stress-responsive signal transducer in higher vertebrate cells / Ken-ichi Yamamoto, Masahiko Kobayashi and Hiroko Shimizu --METHOD 1. Stable transfection of DT40 / Julian E. Sale -- METHOD 2. Basic cell culture conditions / Huseyin Saribasak and Hiroshi Arakawa -- METHOD 3. Excision of floxed-DNA sequences by transient induction of Mer-Cre-Mer / Hiroshi Arakawa -- METHOD 4. Immunoglobulin gene conversion and hypermutation assay by FACS / Hiroshi Arakawa -- METHOD 5. Target screening by PCR / Hiroshi Arakawa -- METHOD 6. Mitotic index determination by flow cytometry / David AF Gillespie and Mark Walker -- METHOD 7. Centrifugal elutriation as a means of cell cycle phase separation and synchronization / David AF Gillespie and Catarina Henriques -- METHOD 8. Preparation of genomic DNA for microarray-based comparative genome hybridization / Robert Kimmel, Amalia Icreverzi, Paul Neiman -- METHOD 9. Analysis of cellular Mg2+ in DT40 cells / Anne-Laure Perraud, Carsten Schmitz, Andrew M. Scharenberg -- METHOD 10. Transient transfection of DT40 / Roger Franklin & Julian E. Sale -- METHOD 11. Retroviral transduction of DT40 / Felix Randow & Julian E. Sale -- METHOD 12. Colony survival assay / Laura. J. Simpson & Julian E. Sale -- METHOD 13. Subcloning DT40 by limiting dilution / Jean-Marie Buerstedde --METHOD 14. Subnuclear immunofluorescence / Dávid Szüts & Julian E. Sale -- METHOD 15. Sister chromatid exchange assay / Laura J. Simpson & Julian E. Sale -- METHOD 16. 2D cell cycle analysis / Roger Franklin & Julian E. Sale -- METHOD 17. Purification of tap-tagged proteins by two-step pull down from DT40 cells / Hiroyuki Kitao and Minoru Takata -- METHOD 18. Synchronization of cells / Eiichiro Sonoda -- METHOD 19. Tranfection of DT40 cells / Huseyin Saribasak and Hiroshi Arakawa -- METHOD 20. Luciferase reporter assay / Frank R. Wettey and Antony P. Jackson -- METHOD 21. Indirect immunofluorescence microscopy / Frank R. Wettey and Antony P. Jackson -- METHOD 22. Quantification of receptor-mediated endocytosis / Frank R. Wettey and Antony P. Jackson -- METHOD 23. Measurement of DNA synthesis and strand breaks using alkaline sucrose density gradient centrifugation / Kouichi Yamada and Jun Takezawa -- METHOD 24. Fractionation of nuclear and cytoplasmic proteins from DT40 cell lines / Yan-Dong Wang and Randolph B Caldwell.
  • Rho GTPases in cancer 2010, Springer
  • Ribosomes 2011, Springer
  • Mechanisms of apoptosis during reovirus infection /P. Clarke ... [et al.] --Poliovirus, pathogenesis of poliomyelitis, and apoptosis /B. Blondel ... [et al.] --Neuronal cell death in alphavirus encephalomyelitis /D. E. Griffin --HSV-induced apoptosis in herpes encephalitis /L. Aurelian --Therole of apoptosis in defense against baculovirus infection in insects /R. J. Clem --Therole of host cell death in Salmonella infections /D. G. Guiney --Role of macrophage apoptosis in the pathogenesis of Yersinia /Y. Zhang, J. B. Bliska --Entamoeba histolytica activates host cell caspases during contact-dependent cell killing /D. R. Boettner, W. A. Petri --Interactions between malaria and mosquitoes : the role of apoptosis in parasite establishment and vector response to infection /H. Hurd, V. Carter, A. Nacer --Apoptosis and its modulation during infection with Toxoplasma gondii : molecular mechanisms and role in pathogenesis /C. G. K. Luder, U. Gross --Modulation of the immune response in the nervous system by rabies virus /M. Lafon --Apoptotic cells at the crossroads of tolerance and immunity /M. Skoberne ... [et al.].
  • It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors. However, when the activity of proteases is not regulated appropriately, disease processes can result, as seen in Alzheimer's disease, cancer metastasis and tumor progression, inflammation and atherosclerosis. Thus it is evident that there is an absolute need for a tighter control of proteolytic activities in different cells and tissues. Aimed at graduate students and researchers with an interest in cellular proteolytic events, Role of Proteases in Cellular Dysfunctions is the second book on Proteases in this series. The book consists of three parts in specified topics based on current literatures for a better understanding for the readers with respect to their subject-wise interests. The first section of this book covers a brief idea about the neuronal disorders and the involvement of proteases such as calpains, caspases and matrix metalloproteases (MMPs). The second section covers the deadly disease cancer and its relation to ubiquitin-proteosomal system, MMPs and serine proteases. The last section is about the role of proteases such as calpains, MMPs and serine protease as well as urokinase type plasminogen activator receptor (uPAR) in causing cardiovascular defects.
  • Ryanodine receptors 2005, Springer
  • Selfish cell 2008, Springer
  • Semaphorins 2007, Springer
    The CRMP family of proteins and their role in Sema3A signaling / Eric F. Schmidt and Stephen M. Strittmatter -- GTPases in semaphorin signaling / Andreas W. Püchel -- Intracellular kinases in semaphorin signaling / Aminul Ahmed and Britta J. Eickholt -- Mical flavoprotein monooxygenases : structure, function and role in semaphorin signaling / Sharon M. Kolk and R. Jeroen Pasterkamp -- Signaling of secreted semaphorins in growth cone steering / Sangwoo Shim and Guo-li Ming -- Modulation of semaphorin signaling by IG superfamily cell adhesion molecules / Ahmad Bechara ... [et al.] -- Proteoglycans as modulators of axon guidance cue function / Joris de Wit and Joost Verhaagen -- Semaphorin signals in cell adhesion and cell migration : functional role and molecular mechanisms / Andrea Casazza, Pietro Fazzari, and Luca Tamagnone -- Semaphorin signaling during cardiac development / Toshihiko Toyofuku and Hitoshi Kikutani -- Semaphorin signaling in vascular and tumor biology / Gera Neufeld ... [et al.].
  • Introduction, Clinical and Technical Aspects--Normal Cytology--Reactive Mesothelial Hyperplasia--Malignant Mesothelioma--A Potential Litigation Diagnosis--Metastatic Cancers--Effusions in Children--Abdominopelvic Washings--Lymphocytic Effusions--Benign Inflammatory and Other Uncommon Conditions--Cerebrospinal Fluid.
  • Sertoli cell biology 2005, ScienceDirect
  • Sigma receptors 2007, Springer
  • Signal transduction 2010, Springer
  • Signal transduction. 2nd ed. 2009, ScienceDirect
    "A reference on cellular-signalling processes, Signal Transduction second edition details the sources, key observations, and experiments that set the scene for recent and current scientific endeavour. Beginning with a historical overview, this book discusses how the concept of chemical messengers arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, and growth factors." "The book further examines more complex signalling cascades, emanating from classic receptors, as well as adhesion molecules, involved in processes such as vision, smell, inflammation, innate and adaptive immunity, glucose homeostasis, cell-fated decisions, cell differentiation, and cell transformation. This revision concludes with a discourse on the targeting of signal-transduction cascades in the treatment of cancer and the structure of protein domains key to the assembly of signalling complexes"--Book jacket.
  • Single cell diagnostics 2007, Springer Protocols
    Noninvasive metabolic assessment of single cells / David K. Gardner -- Laser capture microdissection for analysis of single cells / Nobuki Nakamura ... [et al.] -- Fluorescence in situ hybridization (FISH) on single cells (sex determination and chromosome rearrangements) / Paul N. Scriven and Caroline Mackie Ogilvie -- Single cell PCR for PGD : methods, strategies, and limitations / Karen Sermon and Martine De Rycke -- Real-time quantitative PCR measurement of male fetal DNA in maternal plasma / Bernhard Zimmermann ... [et al.] -- Cell-free fetal DNA plasma extraction and real-time PCR quantification / Jill L. Maron, Kirby L. Johnson, and Diana W. Bianchi -- LATE-PCR and allied technologies : real-time detection strategies for rapid, reliable diagnosis from single cells / Kenneth E. Pierce and Lawrence J. Wangh -- Efficient isothermal amplification of the entire genome from single cells / Karen V. Schowalter, Jolene R. Fredrickson, and Alan R Thornhill -- Comparative genomic hybridization on single cells / Lucille Voullaire and Leeanda Wilton -- Generation of amplified RNAs and cDNA libraries from single mammalian cells / James Adjaye -- Real-time PCR to measure gene expression in single cells / Dagan Wells -- Gender determination and detection of aneuploidy in single cells using DNA array-based comparative genomic hybridization (array CGH) / Dong Gui Hui, Xin Yuan Guan, and Nicole Hussey -- Microarray technology for mutation analysis of low template DNA samples / Chelsea Salvado and David Cram.
  • Smad signal transduction 2006, Springer
  • Sodium calcium exchange 2013, Springer
  • Somatic embryogenesis 2006, Springer
  • Sphingolipids 2013, Springer
    Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids' basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.
  • Heart -- Neuro -- Musculoskeletal -- Kidney -- Eye -- Pancreas -- Hematology -- Skin.
  • Stem cell assays 2007, Springer Protocols
    Derivation of human embryonic stem cells in xeno-free conditions / Mohan C. Vemuri ... [et al.] -- Feeder-layer free culture system for human embryonic stem cells / Michal Amit -- Digital imaging of stem cells by electron microscopy / A. Henry Sathananthan and Stefania A. Nottola -- A controlled-cooling protocol for cryopreservation of human and non-human primate embryonic stem cells / Carol B. Ware and Szczepan W. Baran -- Cell surface markers in human embryonic stem cells / Raj R. Rao, Alison Venable Johnson, and Steven L. Stice -- Generation of a monoclonal antibody library against human embryonic stem cells / Micha Drukker, Christina Muscat, and Irving L. Weissman -- Analytical methods for cancer stem cells / Vinagolu K. Rajasekhar -- Micro RNA profiling : an easy and rapid method to screen and characterize stem cell populations / Uma Lakshmipathy ... [et al.] -- Gene transfer via nucleofection into adult and embryonic stem cells / Uma Lakshmipathy, Shannon Buckley, and Catherine Verfaillie -- RNAi knockdown of transcription factor Pu.1 in the differentiation of mouse embryonic stem cells / Gang-Ming Zou, Meredith A. Thompson, and Mervin C. Yoder -- StemBase : a resource for the analysis of stem cell gene expression data / Christopher J. Porter ... [et al.] -- Isolation of stem cells from human umbilical cord blood / Nishanth P. Reddy, Mohan C. Vemuri, and Reddanna Pallu -- Ex vivo expansion of hematopoietic stem cells from human cord blood in serum-free conditions / Chao-Ling Yao and Shiaw-Min Hwang -- Hematopoietic colony-forming cell assays / Carla Pereira, Emer Clarke, and Jackie Damen -- Assays for alloreactive responses by PCR / Patrick Stordeur -- Immune properties of mesenchymal stem cells / Panagiota A. Sotiropoulou and Michael Papamichail -- Clinical grade expansion of human bone marrow mesenchymal stem cells / Panagiota A. Sotiropoulou, Sonia A. Perez, and Michael Papamichail -- Adenoviral transduction of mesenchymal stem cells / Pablo Bosch and Steven L. Stice -- Directed differentiation of human embryonic stem cells to dendritic cells / Maxim A. Vodyanik and Igor I. Sluvkin -- Insulin-producing cells from embryonic stem cells to dendritic cells / Maxim A. Vodyanik and Igor I. Slukvin -- Insulin-producing cells from embryonic stem cells experimental considerations / Enrique Roche ... [et al.] -- Efficient generation of dopamine neurons from human embryonic stem cells / Chang-Hwan Park and Sang-Hun Lee -- Isolation of oligodendroglial cells from cultured neural stem/progenitors / Frank Zeigler and Stephen G. Hall -- Differentiation of human embryonic stem cells toward the chondrogenic lineage / Wei Seong Toh ... [et al.] -- Cartilage tissue engineering : directed differentiation of embryonic stem cells in three-dimensional hydrogel culture / Nathaniel S. Hwang, Shyni Varghese, and Jennifer Elisseeff.
  • Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modeling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.
  • Part 1. Bone marrow-derived stem cells -- Part 2. Embryonic stem cells -- Part 3. Cancer stem cells.
  • "Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward"--Provided by publisher.
  • Ventricular remodeling in ischemic cardiomyopathy / Stefan Klotz and Daniel Burkhoff -- Myocardial regeneration: which cell and why / Elmostafa El Fahime and Jacques Tremblay -- Cardiac stem cells for myocardial regeneration / Bernardo Nadal-Ginard and Simón Méndez-Ferrer -- A historic recapitulation of myoblast transplantation / Daniel Skuk and Jacques Tremblay -- Myoblast cell transplantation preclinical studies / Doris A. Taylor and Harald Ott -- Skeletal myoblasts: the European experience / Philippe Menasche -- Skeletal myoblasts: the U. S. experience / Edward B. Diethrich -- Progenitor cells for cardiac regeneration / Ana Sánchez and Javier Garcia-Sancho -- Bone marrow derived stem cell for myocardial regeneration: preclinical experience / Bradley Martin and Mark Pittenger --Bone marrow derived stem cell for myocardial regeneration: clinical experience, surgical delivery / Manual Galiñanes -- Autologous mononuclear bone marrow cell transplantation for myocardial infarction: the German experience / Michael Brehm, Tobias Zeus and Bodo E. Strauer -- Autologous mononuclear bone marrow cell transplantation for myocardial infarction: the Spanish experience / Francisco E. Avilés ... [et al.] -- Mobilizing bone marrow stem cells for myocardial repair after acute myocardial infarction / Steve Ellis and Oussama Wazni -- Percutaneous myoblast transplantation: steps in transplantation research / Nabil Dib -- A porcine model of myocardial infarction for evaluation of cell transplantation / Nabil Dib ... [et al.] -- Tissue engineering for myocardial regeneration / Ravi K. Birla -- The role of pet scan in stem cell therapy / Uchechukwa Sampson ... [et al.] -- The measurement of systolic function in the mammalian heart / Blasé Carabello -- Electrophysiological aspects of cell transplantation / Nicholas S. Peters, Nicolas A.F. Chronos and Fernando Tondato -- Regulatory considerations in manufacturing, product testing, and preclinical development of cellular products for cardiac repair / Ellen Areman, Kim Benton and Richard McFarland.
  • In vitro experimentation and research tools -- Tissue engineering and regenerative medicine.
  • Section I. Basic Aspects of Transplantation -- The Frontiers of Organ Transplantation and Cell Therapy / Rafael Matesanz -- Organ Transplantation in the 21th Century / Francisco Ortega -- Immunology and the Challenge of Transplantation / Rebeca Alonso Arias, Antonio López-Vázquez and Carlos López-Larrea -- Cellular Immunotolerance in the Transplant / Marcos Lóez-Hoyos, David San Segundo and Manuel Arias -- Immunosuppression in the ERA of Biological Agents / Josep M. Grinyó, Josep M. Cruzado, Oriol Bestard, J. R. Vidal Castiñeira and Joan Torras -- Transgenic Organs and Xenotransplants / Cristina Costa Vallés and Rafael Máñez Mendiluce -- Cell and Tissue Therapy in Regenerative Medicine / Ana Sánchez, Thomas Schimmang and Javier García-Sancho -- Section II. Adult Stem Cells -- Characteristics of Adult Stem Cells / Manuel A. Gonzalez and Antonio Bernad -- Bone Marrow Transplantation Extends Its Scope / Fermín M. Sánchez-Guijo, Alberto Orfao and María Consuelo del Cañizo -- Biology of Stem Cells: The Role of Microenvironments / Agustín G. Zapata, David Alfaro and Javier García-Ceca --Mobilization and Homing of Hematopoietic Stem Cells / Beatriz Suárez-Álvarez, Antonio López-Vázquez and Carlos López-Larrea -- Great Promise of Tissue-Resident Adult Stem/Progenitor Cells in Transplantation and Cancer Therapies / Murielle Mimeault and Surinder K. Batra -- Multipotent Mesenchymal Stromal Cells: Clinical Applications and Cancer Modeling / René Rodríguez, Javier García-Castro, Cesar Trigueros, Mariano García Arranz and Pablo Menéndez -- Section III. Embryonic Stem Cells -- Neural Stem Cells and Transplantation Studies in Parkinson's Disease / Ricardo Pardal and José López-Barneo -- Biological Impact of Human Embryonic Stem Cells / Miguel Martín and Pablo Menéndez -- Epigenetics of Embryonic Stem Cells / Vincenzo Calvanese and Mario F. Fraga -- New Tools in Regenerative Medicine: Gene Therapy / Miguel Muñoz Ruiz and José R. Regueiro -- Therapeutic Cloning and Cellular Reprogramming / Ramon M. Rodriguez, Pablo J. Ross and Jose B. Cibelli -- Section IV. Stem Cell Regenerative Medicine -- Advances in Stem Cell Therapy / Silvia Pérez López and Jesús Otero Hernández -- Tissue Bioengineering and Artificial Organs / Sara Llames, Eva García, Jesús Otero Hernández and Álvaro Meana.
  • Chapter 1. Promises and Limitations in the Application of Cell Therapy for Tissue Regeneration / Raphael Gorodetsky -- Chapter 2. Adult Non-hematopoietic Stem Cells and Progenitor Cells (aNHSCs) / R. Schäfer and L. Dahéron -- Chapter 3. Screening Approaches for Stem Cells / David G. Buschke, Derek J. Hei, Kevin W. Eliceiri and Brenda M. Ogle -- Chapter 4. Hematopoietic Stem Cells and their Role in Regenerative Medicine / Eitan Fibach -- Chapter 5. Cord and Cord Blood: Valuable Resources with Potential for Liver Therapy / Saba Habibollah, Marcin Jurga, Nico Forraz and Colin McGuckin -- Chapter 6. Induced Pluripotent Stem Cells: Their Role in Modeling Disease and Regenerative Medicine / Yonatan Stelzer and Marjorie Pick -- Chapter 7. Mesenchymal Stromal/Stem Cells from Tissue Repair to Destruction of Tumor Cells / Rita Bussolari, Giulia Grisendi, Luigi Cafarelli, Pietro Loschi, Laura Scarabelli, Antonio Frassoldati, Michela Maur, Giorgio De Santis, Paolo Paolucci, Pierfranco Conte and Massimo Dominici -- Chapter 8. Fibrin-based Matrices to Support Stem Cell-Based Tissue Regeneration / Raphael Gorodetsky, Iris Mironi-Harpaz and Dror Seliktar -- Chapter 9. Culturing Non-hematopoietic Mesenchymal Stromal Cells and Requirements of GMP in Stem Cell-based Therapies / Karen Bieback, Marianna Karagianni, Gerlinde Schmidtke-Schrezenmeier, Natalie Fekete and Hubert Schrezenmeier --Chapter 10. (Stem) Cell Based Therapy for Neurological Disorders / O. Einstein and T. Ben-Hur -- Chapter 11. Mesenchymal Osteogenic Precursors for Bone Repair and Regeneration / Nicola Baldini, Dante Dallari and Francesca Perut -- Chapter 12. Stem Cells and Cartilage Repair / Bernd Rolauffs, Andreas Badke, Kuno Weise, Alan J. Grodzinsky and Wilhelm K. Aicher -- Chapter 13. Stem Cell-based Replacement Tissue for Heart Repair / Ayelet Lesman and Shulamit Levenberg -- Chapter 14. Regeneration of the Vascular System / M. Schleicher, A. J. Huber, H. P. Wendel and U. A. Stock -- Chapter 15. Regenerative Strategies for the Endocrine Pancreas: From Islets to Stem Cells and Tissue Reprogramming / Juan Domínguez-Bendala and Camillo Ricordi -- Chapter 16. Regeneration of the Lower Urinary Tract: Clinical Applications and Future Outlook / Markus Renninger, Bastian Amend, Jörg Seibold, Gerhard Feil, Arnulf Stenzl and Karl-Dietrich Sievert -- Chapter 17. Effective Tissue Repair and Immunomodulation by Mesenchymal Stem Cells within a Milieu of Cytokines / Philip Lim, Shyam A. Patel and Pranela Rameshwar -- Chapter 18. Homing of Mesenchymal Stromal Cells / Reinhard Henschler, Erika Deak and Richard Schäfer.
  • Stem cells 2006, Springer
  • Stem cells 2008, Springer
  • pt. 1. Stem cell biology -- pt. 2. Epigenetic and microRNA regulation in stem cells -- pt. 3. Stem cells for therapeutic applications -- pt. 4. Nuclear reprogramming and induced pluripotent stem cells -- pt. 5. Tissue engineering -- pt. 6. Regenerative medicine.
  • Use of Human Embryonic Stem Cells in Therapy -- Human Neural Stem Cell-based Cell- and Gene-therapy for Neurological Diseases -- Vascular Stem Cell Therapy -- Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications -- Blood Cell Bioprocessing: The Haematopoietic System and Current Status of In-vitro Production of Red Blood Cells -- Bioprocessing Challenges Associated with the Purification of Cellular Therapies -- Separation Technologies for Stem Cell Bioprocessing.
  • The challenge for stem cell therapy: overview of the problem: heart attack and heart failure -- Hematopoietic stem cells for myocardial regeneration -- Mesenchymal stem cells for cardiac therapy -- Multipotent adult progenitor cells -- Mesenchymal progenitor cells for vascular formation and cardiac muscle regeneration -- Umbilical cord blood stem cells for myocardial regeneration and angiogenesis -- Endogenous cardiac stem cells -- Embryonic stem cells for myocardial repair -- Chemokin and homing factor expression in acute myocardial infarction and chronic heart failure -- Stem cell differentiation toward a cardiac myocyte phenotype -- Electrical coupling and/or ventricular tachycardia risk of cell therapy -- Cell therapy for myocardial damage: arrhythmia risk and mechanisms -- Aspects of percutaneous cellular cardiomyoplasty -- Stem cells and myocardial regeneration: open-chest/minimally invasive surgical techniques -- Measures of effective cell based therapies -- Whole bone marrow transplantation -- Clinical angioblast therapy -- Use of skeletal myoblasts for the treatment of chronic heart failure -- Bone marrow and angioblast transplantation -- Strategies for cytokine modification and stem cell mobilization for acute myocardial infarction -- 21 summary and future challenges.
  • Stem cells for myocardial regeneration 2010, Springer Protocols
    Stem cells for myocardial repair and regeneration : where are we today? / Randall J. Lee -- Bone marrow-derived endothelial progenitor cells : isolation and characterization for myocardial repair / Masaaki Ii -- Umbilical cells stem cells for myocardial repair and regeneration / Nicholas Greco and Mary J. Laughlin -- Isolation of resident cardiac progenitor cells by Hoechst 33342 staining / Otmar Pfister ... [et al.] -- Mesenchymal stem cell therapy for cardiac repair / Andrew J. Boyle, Ian K. McNiece, and Joshua M. Hare -- Methods for human embryonic stem cells derived cardiomyocytes cultivation, genetic manipulation, and transplantation / Gil Arbel ... [et al.] -- Experimental cell transplantation therapy in rat myocardial infarction model including nude rat preparation / Wangde Dai and Robert A. Kloner -- Large animal model of heart failure for assessment of stem cells / Sharad Rastogi -- Histopathologic assessment of myocardial regeneration / Naima Carter-Monroe ... [et al.] -- Assessment of myocardial angiogenesis and vascularity in small animal models / Matthew L. Springer -- Superparamagnetic iron oxide labeling of stem cells for MRi tracking and delivery in cardiovascular disease / Dorota A. Kedziorek and Dara L. Kraitchman -- Embryonic stem cell biology : insights from molecular imaging / Karim Sallam and Joseph C. Wu -- Genetic fate-mapping for studying adult cardiomyocyte replenishment after myocardial injury / Sunny S.-K. Chan ... [et al.] -- In vitro electrophysiological mapping of stem cells / Seth Weinberg, Elizabeth A. Lipke, and Leslie Tung -- Assessment of cardiac conduction : basic principles of optical mapping / Chunhua Ding and Thomas H. Everett IV -- Surface patterning for generating defined nanoscale matrices / Karen L. Christman and Heather D. Maynard.
  • Stem cells in regenerative medicine 2009, Springer Protocols
    Derivation and manipulation of murine embryonic stem cells / Alexander Meissner, Sarah Eminli, and Rudolf Jaenisch -- Patterning mouse and human embryonic stem cells using micro-contact printing / Raheem Peerani ... [et al.] -- Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi / Asmin Tulpule and George Q. Daley -- Measurement of cell-penetrating peptide-mediated transduction of adult hematopoietic stem cells / Aziza P. Manceur and Julie Audet -- Stem cell sources for regenerative medicine / Ali M. Riazi, Sarah Y. Kwon, and William L. Stanford -- Investigating the interactions between haemopoietic stem cells and their niche : methods for the analysis of stem cell homing and distribution within the marrow following transplantation / Brenda Williams and Susan K. Nilsson -- Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells / Valérie Cortin, Nicolas Pineault, and Alain Garnier -- Ex vivo generation of human red blood cells : a new advance in stem cell engineering / Luc Douay and Marie-Catherine Giarratana -- Isolation and manipulation of mammalian neural stem cells in vitro / Claudio Giachino, Onur Basak, and Verdon Taylor -- Isolation, expansion, and differentiation of mouse skin-derived precursors / Karl J.L. Fernandes and Freda D. Miller -- Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord / Hynek Wichterle, Mirza Peljto, and Stephane Nedelec -- Transplantation of neural stem/progenitor cells into developing and adult CNS / Tong Zheng ... [et al.] -- Transplantation of embrynic stem cell-derived dopaminergic neurons in MPTP-treated monkeys / Jun Takahashi, Yasushi Takagi, and Hidemoto Saiki -- Isolation and culture of epithelial stem cells / Jonathan A. Nowak and Elaine Fuchs -- Regeneration of skin and cornea by tissue engineering / Danielle Larouche ... [et al.] -- Prospective isolation of mesenchymal stem cells from mouse compact bone / Brenton J. Short, Nathalie Brouard, and Paul J. Simmons -- Isolation, propagation, and characterization of human umbilical cord perivascular cells (HUCPVCs) / Rahul Sarugaser ... [et al.] -- Bone marrow-derived mesenchymal stem cells : isolation, expansion, characterization, viral transduction, and production of conditioned medium / Massimilano Gnecchi and Luis G. Melo -- Template DNA-strand co-segregation and asymmetric cell division in skeletal muscle stem cells / Vasily Shinin, Barbara Gayraud-Morel, and Shahragim Tajbakhsh -- Isolation and grafting of single muscle fibres / Charlotte A. Collins and Peter S. Zammit -- Differentiation and dynamic analysis of primitive vessels from embryonic stem cells / Gefei Zeng and Victoria L. Bautch -- Derivation of contractile smooth muscle cells from embryonic stem cells / Sanjay Sinha, Mark H. Hoofnagle, and Gary K. Owens -- Islet-derived progenitors as a source of in vitro islet regeneration / Stephen Hanley and Lawrence Rosenberg -- Isolation and characterization of hepatic stem cells, or "oval cells," from rat livers / Thomas D. Shupe ... [et al.] -- Reprogramming of liver to pancreas / Shifaan Thowfeequ ... [et al.]
  • "In this state-of-the-art exploration of a hugely dynamic and fast-evolving field of research, leading researchers share their collective wisdom on the role that stem cells could play in the context of physiological stress and lung injury. The text focuses on reviewing the most relevant -- and recent -- ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages. Our entire blood supply passes through the lung's alveolar units during oxygenation. This interaction with the outside world, along with the intricacies of its structure, makes the lung a highly susceptible organ that is vulnerable to numerous types of injury and infection. This means that the mechanisms of lung repair are in themselves correspondingly complex. Because of their multipotentiality, as well as the fact of the lung's relatively rapid cell turnover, stem cells are thought to be an important alternative cell-base therapy in lung injury. Despite the controversial nature of stem cell research, there has been growing interest in both local and endogenous stem cells in the lung. This highly topical book with chapters on everything from using mesenchymal stem cells in lung repair to the effect of physical activity on the mobilization of stem and progenitor cells, represents an exciting body of work by outstanding investigators and will be required reading for those with an interest in the subject."--Publisher's website.
  • Stem cells. 1st ed. 2002, ScienceDirect
  • Stem cells. 1st ed. 2011, ScienceDirect
    Biology of the cell -- Embryonic development -- What are stem cells? -- Of mice and men: the history of the stem cell -- Origins and types of stem cells -- Cloning -- Regenerative medicine: clinical applications of stem cells -- Cardiomyocytes from stem cells: what can we do with them? -- Stem cell tourism --Stem cells in cancer and cancer stem cells -- Stem cells for discovery of effective and safe new drugs -- Legal and intellectual property issues associated with stem cells -- Stem cell perspectives: a vision of the future.
  • Sticky synapse 2009, Springer
  • Part I. Structure and ligands of NCAM. -- Structural biology of NCAM / Vladislav Soroka, Christina Kasper, Flemming M. Poulsen. -- Extracellular protein interactions mediated by the neural cell adhesion molecule, NCAM: heterophilic interactions between NCAM and cell adhesion molecules, extracellular matrix proteins, and viruses / Janne Nielsen, Nikolaj Kulahin, Peter S. Walmod. -- Intracellular (intracelluar) ligands of NCAM / Bettina Buttner, Rudiger horstkorte. -- Role of ATP in the regulation of NCAM function / Martin V. Hubschmann, Galina Skladchikova. -- Part II. NCAM and plysialic acid. -- Polysialylation of NCAM / Herbert Hildebrandt, Martina Muhlenhoff, Rita Gerardy-Schahn. -- Structural basis for the polysialylation of the neural cell adhesion molecule / Karen J. Colley. -- Role of PSA-NCAM in adult neurogenesis / Eduardo Gascon, Laszlo Vutskits, Jozsel Zoltan Kiss. -- Use of PSA-NCAM in repair of the central nervous system / Abderrahman El Maarouf, Urs Rutishauser. -- Part III. NCAM-mediated signal transduction. -- Signaling pathways involved in NCAM-induced neurite outgrowth / Dorte Kornerup Ditlevsen, Kateryna Kolkova. -- Role of the growth-associated protein GAP-43 in NCAM mediated neurite outgrowth / Irina Korshunova, Mark Mosevitski. -- Neural cell adhesion molecule NCAM and lipid rafts / Gro Klitgaard Povlsen, Dorte Kornerup Ditlevsen. -- Neural cell adhesion molecule and epidermal growth factor receptor: signaling crosstalk / Gro Klitgaard Polvsen. -- Part IV. NCAM metabolism. -- Biosynthesis of NCAM / Kateryna Kolkova. -- Soluble NCAM / Thomas Secher. -- Part V. NCAM, synapses, emotions, and memory. -- Role of NCAM in spine dynamics and synaptogenesis / D. Muller, P. Mendez, M. DeRoo, P. Klauser, S. Steen, and L. Poglia. -- NCAM in long-term potentiation and learning / Barbara P. Hartz, Lars Christian B. Roon. -- Role of NCAM in emotion and learning / Lisa Conboy, Reto Bisaz, Kamila Markram, Carment Sandi. -- Part VI. NCAM in disease. -- NCAM in neuropsychiatric and neurodegenerative disorders / Leann H. Brennaman, Patricia F. Maness. -- Neural cell adhesion molecule in cancer: expression and mechanisms / Silvia Zecchini, Ugo Caallaro. -- Part VII. Pharmacology of NCAM: NCAM mimetics. -- NCAM mimetic peptides: an update / Vladimir Berezin, Elisabeth Bock. -- Synthetic NCAM-derived ligands of the fibroblast growth factor receptor / Stine maria Hansen, Shizhong Li, Elisabeth Bock, Vladimir Berezin. -- Dendritic spine and synapse morphological alterations induced by neural cell adhesion molecule mimetic / Michael Stewart, Victor Popov, Nikolai Medvedev, Paul Giabbon, Nicola Corbett, Igor Kraev, Heather Davies. -- Part VIII. Orthologs and paralogs of NCAM. -- Fasciclin II: the NCAM ortholog in Drosophila melanogaster / Lars V. Kristiansen, Michael Hortsch. -- Neural cell adhesion molecule NCAM2/OCAM/RNCAM, a close relative to NCAM / Nikolaj Kulahin, Peter S. Walmod. -- Part IX. Conclusion. -- Honoring Dr. Elisabeth Bock / Vladimir Berezin.
  • Introduction: The GW Body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology -- The Discovery of GW Bodies -- The Discovery and Analysis of P Bodies -- Autoantibodies to Argonaute 2 (Su Antigen) -- GW/P-Bodies and Autoimmune Disease -- Function of GW182 and GW Bodies in siRNA and miRNA Pathways -- Post-transcriptional Stimulation of Gene Expression by MicroRNAs -- Gawky (GW) is the Drosophila melanogaster GW182 Homologue -- The Role of GW182 Proteins in miRNA-Mediated Gene Silencing -- Quantifying Argonaute Proteins In and Out of GW/P-Bodies: Implications in microRNA Activities -- Deadenylation and P-Bodies -- Relationship of GW/P-Bodies with Stress Granules -- Relationship of Other Cytoplasmic Ribonucleoprotein Bodies (cRNPB) to GW/P Bodies -- An SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 -- Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research.
  • Angiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis. A substantial increase in the research effort over the past decade has deepened our understanding of the basic mechanisms underlying angiogenesis and lymphangiogenesis, promoting the development of promising therapeutics for the clinical management of vascular-related diseases.
  • Th 17 cells 2009, Springer
  • Therapy with cultured cells 2010, CRCnetBASE
    Cultured cells for therapy are now being prepared by industries in the US, Japan and Korea and are used in the aforesaid countries as well as France, Sweden and Greece, for the treatment of disease. This title describes the discoveries in the author's laboratory that led to therapy with cultured cells.
  • Engineering of Fluorescent Reporters into Redox Domains to Monitor Electron Transfers /Derek Parsonage ... [et al.] --Blot-Based Detection of Dehydroalanine-Containing Glutathione Peroxidase with the Use of Biotin-Conjugated Cysteamine /Sue Goo Rhee, Chun-Seok Cho --Analysis of the Redox Regulation of Protein Tyrosine Phosphatase Superfamily Members Utilizing a Cysteinyl-Labeling Assay /Benoit Boivin, Nicholas K. Tonks --Measuring the Redox State of Cellular Peroxiredoxins by Immunoblottin /Andrew G. Cox, Christine C. Winterbourn, Mark B. Hampton --Thiol Redox Transitions by Thioredoxin and Thioredoxin-Binding Protein-2 in Cell Signaling /Eiji Yoshihara ... [et al.] --Detection of Protein Thiols in Mitochondrial Oxidative Phosphorylation Complexes and Associated Proteins /Kelly K. Andringa, Shannon M. Bailey --Mitochondrial Thioredoxin Reductase: Purification, Inhibitor Studies, and Role in Cell Signaling /Maria Pia Rigobello, Alberto Bindoli --Measuring Mitochondrial Protein Thiol Redox State /Raquel Requejo ... [et al.] --Measurement of Extracellular (Exofacial) Versus Intracellular Protein Thiols /Jolanta Skalska, Steven Bernstein, Paul Brookes --Redox Clamp Model for Study of Extracellular Thiols and Disulfides in Redox Signaling /Young-Mi Go, Dean P. Jones --Redox State of Human Serum Albumin in Terms of Cysteine-34 in Health and Disease /Karl Oettl, Gunther Marsche --Methods for Studying Redox Cycling of Thioredoxin in Mediating Preconditioning-Induced Survival Genes and Proteins /Chuang C. Chiueh --Oxidative Stress, Thiol Redox Signaling Methods in Epigenetics /Isaac K. Sundar ... [et al.] --Characterization of Protein Targets of Mammalian Thioredoxin Reductases /Anton A. Turanov, Dolph L. Hatfield, Vadim N. Gladyshev --Alteration of Thioredoxin Reductase 1 Levels in Elucidating Cancer Etiology /Min-Hyuk Yoo ... [et al.] --Regulation of Apoptosis Signal-Regulating Kinase 1 in Redox Signaling /Kazumi Katagiri, Atsushi Matsuzawa, Hidenori Ichijo --Protocols for the Detection of S-Glutathionylated and S-Nitrosylated Proteins In Situ /Scott W. Aesif, Yvonne M.W. Janssen-Heininger, Niki L. Reynaert --Synthesis, Quantification, Characterization, and Signaling Properties of Glutathionyl Conjugates of Enals /Sanjay Srivastava ... [et al.] --Thioredoxin and Redox Signaling in Vasculature--Studies Using Trx2 Endothelium-Specific Transgenic Mice /Wang Min ... [et al.]
  • Tight junctions 2006, Springer
    Evolution of the transporting epithelium phenotype / Marcelino Cereijido ... [et al.] -- Occludin, a constituent of tight junctions / Yan-Hua Chen, Daniel A. Goodenough and Qun Lu -- Tight junction channels / James Melvin Anderson and Christina M. Van Itallie -- JAM family proteins: tight junction proteins that belong to the immunoglobulin superfamily / Susumu Hirabayashi and Yutaka Hata -- Cingulin, a cytoskeleton-associated protein of the tight junction / Laurent Guillemot and Sandra Citi -- ZO proteins and tight junction assembly / Alan S. Fanning -- TJ proteins that make round trips to the nucleus / Esther Lopez-Bayghen ... [et al.] -- Tight junctions and the regulation of epithelial -- Cell proliferation and gene expression / Emma Kavanagh ... [et al.] -- Tight junction proteins and cancer / Isabel J. Latorre, Kristopher K. Frese and Ronald T. Javier -- Regulation of paracellular transport across tight junctions by the actin cytoskeleton / Matthias Bruewer and Asma Nusrat -- Regulation of tight junctions' functional integrity: role of a urinary factor, lipids, and ouabain / Liora Shoshani ... [et al.] -- Tight junctions during development / Bhavwanti Sheth ... [et al.] -- Tight junctions and the blood-brain barrier / Hartwig Wolburg, Andrea Lippoldt, and Klaus Ebnet -- Tight junctions in CNS myelin / Jeff M. Bronstein and Seema Tiwari-Woodruff -- Tight junction modulation and its relationship to drug delivery / Noha N. Salama, Natalie D. Eddington and Alessio Fasano.
  • 1. Cytomechanics in connective tissue repair and engineering / Robert A. Brown -- 2. Scleroderma lung fibroblasts : contractility and connective tissue growth factor / Galina S. Bogatkevich ... [et al.] -- 3. Functional assessment of fibroblast heterogeneity by the cell-surface glycoprotein thy-1 / Carolyn J. Baglole ... [et al.] -- 4. Tissue repair in asthma : the origin of airway subepithelial fibroblasts and myofibroblasts / Sabrina Mattoli -- 5. Experimental models to study the origin and role of myofibroblasts in renal fibrosis / Michael Zeisberg, Mary A. Soubasakos and Raghu Kalluri -- 6. Epithelial to mesenchymal transition of mesothelial cells as a mechanism responsible for peritoneal membrane failure in peritoneal dialysis patients / Abelardo Aguilera ... [et al.] -- 7. FIZZy alveolar epithelial cells induce myofibroblast differentiation / Sem H. Phan -- 8. Pro-invasive molecular cross-signaling between cancer cells and myofibroblasts / Olivier De Wever and Marc Mareel -- 9. Proangiogenic implications of hepatic stellate cell transdifferentiation into myofibroblasts induced by tumor microenvironment / Elvira Olaso ... [et al.] -- 10. Matrix metalloproteinases, tissue inhibitors of metalloproteinase and matrix turnover and the fate of hepatic stellate cells / Aqeel M. Jamil and John P. Iredale -- 11. Innate immune regulation of lung injury and repair / Dianhua Jiang ... [et al.] -- 12. An Eye on repair : myofibroblasts in corneal wounds / James V. Jester.
  • TNF pathophysiology 2010, Karger
    TNF is a multifunctional proinflammatory cytokine central to the development and homeostasis of the immune system and a regulator of cell activation, differentiation and death. Recent decades have seen an enormous scientific and clinical interest in the function of TNF in physiology and disease. A vast amount of data has been accumulated at the biochemical, molecular and cellular level, establishing TNF as a prototype for in-depth understanding of the physiological and pathogenic functions of cytokines. This volume covers several current aspects of TNF regulation and function, including transcriptional and posttranscriptional control mechanisms, cellular modes of action, signaling networks that mediate its effect, involvement in pathogenesis and clinical outcomes of TNF antagonists. It combines basic science at the molecular and cellular level with research in animal models of disease and clinical findings to provide a comprehensive review of recent developments in TNF biology. A thorough understanding of the mechanisms by which this key molecular player is produced and functions to regulate cell biology, immunity and disease postulates novel paradigms on how genes contribute to the development and physiology of biological systems.
  • Transcription factors 2010, Springer Protocols
    A review of post-translational modifications and subcellular localization of Ets transcription factors : possible connection with cancer and involvement in the hypoxic response / Céline Charlot ... [et al.] -- Regulation of transcription factor function by targeted protein degradation : an overview focusing on p53, c-Myc, and c-Jun / Jukka Westermarck -- Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents / Aldo Giudice, Claudio Arra, and Maria C. Turco -- Subnuclear localization and intranuclear trafficking of transcription factors / Sayyed K. Zaidi ... [et al.] -- Analysis of ligand-dependent nuclear accumulation of Smads in TGF-[beta] signaling / Douglas A. Chapnick and Xuedong Liu -- Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1 / Richard Y.M. Ma ... [et al.] -- Coupling of dephosphorylation and nuclear export of Smads in TGF-[beta] signaling / Fangyan Dai ... [et al.] -- Assessing sequence-specific DNA binding and transcriptional activity of STAT1 transcription factor / Thomas Meyer and Uwe Vinkemeier -- Analysis of nuclear export using photoactivatable GFP fusion proteins and interspecies heterokaryons / Kerry-Ann Nakrieko, Iordanka A. Ivanova, and Lina Dagnino -- Determination of nuclear localization signal sequences for Krüppel-like factor 8 / Tina S. Mehta, Farah Monzur, and Jihe Zhao -- Methods to measure nuclear export of [beta]-catenin using fixed and live cell assays / Manisha Sharma and Beric R. Henderson -- Imaging of transcription factor trafficking in living cells : lessons from corticosteroid receptor dynamics / Mayumi Nishi -- Hypoxia-inducible factors : post-translational crosstalk of signaling pathways / Elitsa Y. Dimova and Thomas Kietzmann -- The basic helix-loop-helix-leucine zipper gene Mitf : analysis of alternative promoter choice and splicing / Kapil Bharti ... [et al.] -- Phosphorylation control of nuclear receptors / Sébastien Lalevée, Christine Ferry, and Cécile Rochette-Egly -- Regulation of Krüpple-like [i.e. Krüppel-like] factor 5 by targeted protein degradation / Ceshi Chen -- Post-translational control of ETS transcription factors : detection of modified factors at target gene promoters / Li Li, Janice Saxton, and Peter E. Shaw -- Integration of protein kinases into transcription complexes : identifying components of immobilised in vitro pre-initiation complexes / Hong-Mei Zhang ... [et al.] -- Post-translational modification of p53 by ubiquitin / Chunhong Yan -- Phosphorylation-dependent regulation of SATB1, the higher-order chromatin organizer and global gene regulator / Dimple Notani ... [et al.] -- In vivo and in vitro tools to identify and study transcriptional regulation of USF-1 target genes / Marie-Dominique Galibert and Sébastien Corre -- Measuring the absolute abundance of the Smad transcription factors using quantitative immunoblotting / David C. Clarke and Xuedong Liu -- Flow cytometry analysis of transcription factors in T lymphocytes / Diana I. Albu, Danielle Califano, and Dorina Avram -- Identification of specific protein/E-box-containing DNA complexes : lessons from the ubiquitously expressed USF transcription factors of the b-HLH-LZ super family / Marie-Dominique Galibert and Yorann Baron.
  • 1. The Stem cell state / Gary R. Hime, Helen E. Abud -- 2. Induction of pluripotency / Corey Heffernan, Jun Liu, Huseyin Sumer -- pt. I. Model stem cell systems (A): invertebrate -- 3. Germline stem cells and their regulation in the nematode Caenorhabditis elegans / Aaron Kershner, Sarah L. Crittenden, Kyle Friend, Erika B. Sorensen, Douglas F. Porter -- 4.Transcriptional and post-transcriptional regulation of Drosophila germline stem cells and their differentiating progeny / Helen White-Cooper, Simona Caporilli -- 5. Stem cells in the Drosophila digestive system / Xiankun Zeng, Chhavi Chauhan, Steven X. Hou -- 6. Mechanisms of asymmetric progenitor divisions in the Drosophila central nervous system / Rita Sousa-Nunes, W. Gregory Somers -- pt. II. Model stem cell systems (B): vertebrate -- 7. Transcriptional/translational regulation of mammalian spermatogenic stem cells / Cathryn A. Hogarth -- 8. Transcriptional regulation and specification of neural stem cells / Kimberly J. Christie, Ben Emery, Mark Denham, Helena Bujalka, Holly S. Cate -- 9. Transcriptional control of epidermal stem cells / Briana Lee, Xing Dai -- 10. Regulation of intestinal stem cells by WNT and notch signalling / Katja Horvay, Helen E. Abud -- 11. Transcriptional regulation of haematopoietic stem cells / Adam C. Wilkinson, Berthold Göttgens -- 12. The Regulation of mesenchymal stem cell differentiation / David Cook, Paul Genever -- pt. III. Molecular families implicated in stem cell regulation -- 13. The Musashi family of RNA binding proteins: master regulators of multiple stem cell populations / Jessie M. Sutherland, Eileen A. McLaughlin, Gary R. Hime, Nicole A. Siddall -- 14. JAK-STAT signaling in stem cells / Rachel R. Stine, Erika L. Matunis -- 15. Myc in stem cell behaviour: insights from Drosophila / Leonie M. Quinn, Julie Secombe, Gary R. Hime -- 16. The Role of nuclear receptors in embryonic stem cells / Qin Wang, Austin J. Cooney -- 17. Epigenetic regulation of stem cells / Anton Wutz -- 18. Regulation of stem cell populations by microRNAs / Julie Mathieu, Hannele Ruohola-Baker -- 19. Myb and the regulation of stem cells in the intestine and brain: a tale of two niches / Jordane Malaterre, Lloyd Pereira, Robert G. Ramsay.
  • v. 2 2008 Springer
    v. 1. Basic and clinical biology -- v. 2. Cancer treatment and therapy.
  • Translation initiation 2007, ScienceDirect
    Purification of FLAG-tagged eukaryotic initation factor 2B complexes, subcomplexes, and fragments from Saccharomyces cerevisiae / Sarah S. Mohammad-Qureshi ... [et al.] -- In vivo deletion analysis of the architecture of a multiprotein complex of translation initiation factors / Klaus H. Nielsen and Leos̆ Valás̆ek -- An approach to studying the localization and dynamics of eukaryotic translation factors in live yeast cells / Susan G. Campbell and Mark P. Ashe -- In vitro and tissue culture methods for analysis of translation initiation on the endoplasmic reticulum / Samuel B. Stephens and Christopher V. Nicchitta -- Mammalian stress granules and processing bodies / Nancy Kedersha and Paul Anderson -- Methods to analyze micro-RNA-mediated control of mRNA translation / Jennifer L. Clancy ... [et al.] -- Methods for studying signal-dependent regulation of translation factor activity / Xuemin Wang and Christopher G. Proud -- Analysis of mRNA translation in cultured hippocampal neurons / Yi-Shuian Huang and Joel D. Richter -- Detecting ribosomal association with the 5' leader of mRNAs by ribosome density mapping (RDM) / Naama Eldad and Yoav Arava -- Genome-wide analysis of mRNA polysomal profiles with spotted DNA microarrays / Danial Melamed and Yoad Arava -- Synthesis of anti-reverse cap analogs (ARCAs) and their applications in mRNA translation and stability / Ewa Grudzien-Nogalska ... [et al.] -- Methods for identifying compounds that specifically target translation / Letizia Brandi ... [et al.] -- Identifying small molecule inhibitors of eukaryotic translation initiation / Regina Cencic, Francis Robert, and Jerry Pelletier -- Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product pateamine A / Woon-Kai Low ... [et al.].
  • Translational stem cell research : what is possible today and what still remains to be achieved? -- Translating stem cell research knowledge from bench to bedside : ethical issues -- Creation of human-animal entities for translational stem cell research : scientific, ethical and regulatory challenges -- Stem cell banking for translational stem cell research or stem cell-based therapies -- Translational stem cell research and commercial funding -- Patenting of human stem cell-based inventions : scientific, ethical and regulatory issues -- From general public to researchers, and vice versa : communication issues in translational stem cell research -- Translational stem cell research and its psychological implications -- Ethical evaluation of translational stem cell research projects in research ethics committees -- Looking at the future of translational stem cell research and stem cell-based therapeutic applications : risks, long-term effects, and priority setting.
  • The establishment of composite tissue allotransplantation as a clinical reality / Joseph E. Murray -- The evolution of composite tissue allotransplantation: the twentieth century realization of "Cosmas and Damian" / Chad R. Gordon ... [et al.] -- The impact of the discovery of cyclosporine on transplantation of composite tissue allografts / Zsolt T. Csapo, Bence Forgacs, and Barry D. Kahan -- The first limb transplants with cyclosporine / Christopher J. Salgado, Samir Mardini, and Charles W. Hewitt -- Translational research in composite tissue allotransplantation / Linda C. Cendales, David E. Kleiner, and Allan D. Kirk -- Relative antigenicity of allograft components and differential rejection / Jignesh Unadkat ... [et al.] -- On the road to tolerance induction in composite tissue allotransplantation / Mark A. Hardy -- Donor-specific tolerance / Au H. Bui, Gerald Lipshutz, and Jerzy Kupiec-Weglinski -- Immune tolerance induction: basic concepts for composite tissue allotransplantation / Patricio Andrades, Clement Asideu, and Judith M. Thomas -- Allograft survival with calcineurin inhibitors / Neil F. Jones and Esther Voegelin -- Long-term prevention of rejection and combination drug therapy / Thomas H. Tung -- Locoregional immunosuppression in composite tissue allografting / Scott A. Gruber -- New approaches to antibody therapy / Dalibor Vasilic, Moshe Kon, and Cedric G. Francois -- World experience of hand transplantation-independent assessment / W.P. Andrew Lee, Justin M. Sacks, and Elaine K. Horibe -- Hand transplantation: Lyon experience / Palmina Petruzzo ... [et al.] -- Hand transplantation: the Louisville experience / Vijay S. Gorantla and Warren C. Breidenbach III -- Hand transplantation: the Innsbruck experience / Stefan Schneeberger, Marina Ninkovic, and Raimund Margreiter -- Vascularized bone marrow transplantation / Chau Y. Tai ... [et al.] -- Vascularized bone marrow transplantation: pathology of composite tissue transplantation-induced graft-versus-host-disease / Rajen Ramsamooj and Charles W. Hewitt -- Immune cell redistribution after vascularized bone marrow transplantation / Waldemar L. Olszewski and Marek Durlik -- Vascularized knee transplantation / Michael Diefenbeck and Gunther O. Hofmann -- Tracheal transplantation / Gabriel M. Marta and Walter Klepetko -- Laryngeal transplantation / Robert R. Lorenz and Marshall Strome -- Face transplantation / Maria Siemionow and Galip Agaoglu -- The role of allografts in lower extremity reconstruction / Milton B. Armstrong, Ricardo Jimenez-Lee, and Eddie Manning -- Skin allografts in scalp reconstruction / Peter C. Neligan -- Abdominal wall transplantation / Chau Y. Tai and Susan E. Mackinnon -- Live-donor nerve transplantation / Scott A. Gruber and Pedro Mancias -- Ethical and policy concerns of hand/face transplantation / Rhonda Gay Hartman -- Ethical debate on human face transplantation / François Petit -- Psychosocial issues in composite tissue allotransplantation / Barckley Storey ... [et al.] -- Composite tissue transplantation in the twenty-first century / Kirby S. Black and Charles W. Hewitt.
  • Transport in biological media 2013, ScienceDirect
    Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible. Provides detailed mathematical model development to interpret experiments and provides current modeling practices Provides a wide range of biological and clinical applicationsIncludes physiological descriptions of models.
  • The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.
  • Two-component signaling systems. Part A-C pt. A-B, C, 2007, 2010., ScienceDirect
    pt. B, 2007 ScienceDirect
    pt. C, 2010 ScienceDirect
    Pt. A. Computational analyses of sequences and sequence alignments ; Biochemical and genetic assays of individual components of signaling systems ; Physiological assays and readouts -- Pt. B. Structural approaches ; Reconstritution of heterogeneous systems ; Intracellular methods and assays ; Genome-wide analyses of two-component systems.
  • pt. B ScienceDirect
    pt. C ScienceDirect
  • Part I. Pandemic Influenza Overview -- Pandemic influenza as a current threat -- Antigenic cross-reactivity among H5N1 Viruses -- -- Part II. Current Approaches for Human and Avian Vaccine Production -- Seasonal influenza vaccines -- Generation and characterization of candidate vaccine viruses for pre-pandemic influenza vaccines -- Live attenuated vaccines for pandemic influenza -- Influenza vaccines for avian species -- Development and application of avian influenza vaccines in China -- -- Part III. Novel Vaccine Approaches -- Designing vaccines for pandemic influenza -- Attenuated influenza virus vaccines with modified NS1 proteins -- DNA Vaccines against Influenza viruses -- Recombinant proteins produced in insect cells -- Influenza neuraminidase as a vaccine antigen -- Recombinant vectors as influenza vaccines -- Influenza virus-like particles as pandemic vaccines -- Pandemic influenza vaccines -- Adjuvants for pandemic influenza vaccines -- -- Part IV. Novel Approaches of Vaccine Delivery -- Transcutaneous immunization with influenza vaccines -- Microneedle-based vaccines -- -- Part V. Vaccine Evaluation, Production and Distribution -- Animal models for evaluation of influenza vaccines -- Immunosenescence and influenza vaccine efficacy -- Vaccines for pandemic influenza: summary of recent clinical trials -- Considerations for licensure of influenza vaccines with pandemic and pre-pandemic indications -- Strategies for broad global access to pandemic influenza -- Prioritization of pandemic influenza vaccine: rationale and strategy for decision-making.
  • For a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism. The multi-faceted interplay between viral and cellular factors during virus entry is a fascinating field of study, which can provide important insight into viral pathogenesis and define new targets for intervention. This book provides a comprehensive overview of this exciting field of research.
  • Water and the cell 2006, Springer
  • Xenopus protocols 2005, Springer Protocols
  • Part I. Cellular Biology -- Chapter 1. Analyzing Retinal Axon Guidance in Zebrafish / Fabienne E. Poulain, John A. Gaynes, Cornelia Stacher Hörndli, Mei-Yee Law, Chi-Bin Chien -- Chapter 2. Imaging Blood Vessels in the Zebrafish / Makoto Kamei, Sumio Isogai, Weijun Pan, Brant M. Weinstein -- Chapter 3. Medaka Haploid Embryonic Stem Cells / Yunhan Hong -- Part II. Developmental and Neural Biology -- Chapter 4. Neurogenesis / Prisca Chapouton, Leanne Godinho -- Chapter 5. Studying Peripheral Sympathetic Nervous System Development and Neuroblastoma in Zebrafish / Rodney A. Stewart, Jeong-Soo Lee, Martina Lachnit, A. Thomas Look, John P. Kanki, Paul D. Henion -- Chapter 6. Analysis of the Retina in the Zebrafish Model / Andrei Avanesov, Jarema Malicki -- Chapter 7. Photoreceptor Structure and Development: Analyses using GFP Transgenes / Brian D. Perkins, James M. Fadool -- Chapter 8. Physiological Recordings from Zebrafish Lateral-Line Hair Cells and Afferent Neurons / Josef G. Trapani, Teresa Nicolson -- Chapter 9. Zebrafish Kidney Development / Iain A. Drummond, Alan J. Davidson -- Chapter 10. Molecular Regulation of Pancreas Development in Zebrafish / Robin A. Kimmel, Dirk Meyer -- Chapter 11. Monitoring Sleep and Arousal in Zebrafish / Jason Rihel, David A. Prober, Alexander F. Schier -- Chapter 12. Use of Flatbed Transparency Scanners in Zebrafish Research: Versatile and Economical Adjuncts to Traditional Imaging Tools for the Danio rerio Laboratory / Charles A. Lessman, Michael R. Taylor, Wilda Orisme, Ethan A. Carver.
Displaying all 424 matches

Shortcut to Licensed Content

Lane Gateway to Licensed Content

  • Select "Add to Favorites" (click “Continue” if you see a security alert)
  • From the "Create in" menu, select “Links” (IE7) or “Favorites Bar” (IE8, IE9) to install

Shortcut for iPhone

Lane Gateway to Licensed Content

  • Drag this button to your Safari bookmarks bar
  • Open iTunes and sync your iPhone; make sure "Sync Safari Bookmarks" under iPhone Info tab is selected
  • To invoke the bookmarklet on your iPhone, open Safari and tap the "Bookmarks" icon
  • Tap "Bookmarks Bar"
  • Tap "Lane Proxy Bookmarklet"

What is it?

This shortcut (Lane proxy bookmarklet) gives you access to resources licensed by the library even when you're not coming from a Lane or a Stanford IP address.

While we'd like Lane to be your gateway to our licensed content, we recognize that links to books, articles and journals come from a variety of different sources (Google, your email, RSS reader, etc.).

Lane Proxy Bookmarklet in the Bookmarks Bar
Up arrow

When installed, it will look your browser bookmark.

At the page you would like to proxy, click the "Lane Gateway to Licensed Content" to invoke it.

If Lane licenses that content, you'll get access as if you were on campus.

How does it work?

This shortcut (Lane proxy bookmarklet) is a combination of a browser bookmark and a JavaScript application. In other words, it's a bookmark that can be programmed to do things. The Lane proxy bookmarklet simply prepends the Lane proxy URL to the current URL in your browser.

This allows you to view the URL as though you were on campus, giving you access to materials licensed for use by the Stanford academic community.

If you're not authenticated, you'll be prompted for your SUNetID and password.

Don't see the Toolbar, Bookmarks, or Links or Favorites bar?

FireFox

From the "View" menu, select "Toolbars" & choose "Bookmarks Toolbar"

Safari

From the "View" menu, choose "Show Bookmarks Bar"

Chrome

From the "View" menu, choose "Always Show Bookmarks Bar"

Internet Explorer

IE controller bar
  • Right-click in a clear area near the browser address bar
  • In the menu, check a box next "Links" (IE7) or "Favorites" (IE8, IE9)
  • Managing IE Favorites

Caveats

This shortcut (Lane proxy bookmarklet) only works with resources Lane has licensed and configured to work with our proxy server.

If invoked on a resource we do not license and/or have not yet configured, you will see an error message:

The Lane proxy server cannot complete your request because this host has not been configured properly.

We make no attempt to configure our proxy server for every resource, only those we license and for which a Stanford IP address grants access.

Drag this button onto your browser toolbar to install.

  • Right click this button
  • Select "Add to Favorites", click "Continue" if you see a security alert
  • In "Create in" menu, select "Links" (IE7) or "Favorites Bar" (IE8, IE9) to install

Drag this button onto Safari Bookmarks bar to install.

There are 120 high level MeSH Subject Headings under which all MeSH terms fall. Choose a subject heading to see the journals Lane offers in that subject area.

 

[print] 2014

New Book

Authored by
Stanford Alumni - Jeremy M. Berg
and
Michelle L. Kienholz

Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides one-click access to important clinical resources; includes evidence-based diagnosis and treatment guidelines, Books, EBM articles, Ovid MEDLINE, Drug facts and comparisons, Drug interaction facts, guidelines from National Guideline Clearinghouse, patient handouts (English and Spanish), and local content.MD consult provides access to textbooks, electronic journals, practice guidelines, drug information, and patient education handouts.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.