Books by Subject

all 320 titles

Biotechnology

  • 2006 CRCnetBASE
    edited by Nick Quirke.
  • 2012 Springer
    Kursad Turksen, editor.
  • 2016 Springer
    M. Cristina Vega, editor.
    Also available: Print – 2016
  • 2013 Springer
    Pratyoosh Shukla, Brett I. Pletschke, editors.
    Improvement of thermostable enzyme with sugar metabolic activity by targeted mutagenesis -- Glycoside hydrolases for modification of glycosylation in polyphenolic antioxidants -- On the enzyme specificity for the synthesis of prebiotic galacto-oligosaccharides -- Microbial mannanases: properties and applications -- Enzyme Synergy for Enhanced Degradation of Lignocellulosic Waste -- Manganese peroxidase: molecular diversity, heterologous expression and applications -- Advance Techniques in Enzyme Research -- Regulatory motif identification in biological sequences: An overview of computational methodologies -- Structural, Molecular and Functional Aspects of Chitin deacetylase -- Role of enzymes and proteins in plant -- microbe interaction : A study of M. oryzae vs Rice -- Industrial enzyme applications in biorefineries for starchy materials.
  • 2006 Springer
    edited by Gerhard Spekowius and Thomas Wendler.
  • 2012 Springer
    Hossein Baharvand, Nasser Aghdami, editors.
    Advances in stem cell research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
  • 2013 ebrary
    Michael J. Hyde and James A. Herrick, editors.
    Faith in science : professional and public discourse on regenerative medicine / Tristan Keys, Nancy M. P. King, and Anthony Atala -- From Arrowsmith to Atwood : how did we come to disrespect science? / Ronald M. Green -- The "warfare" of science and religion and science's ethical profile / Thomas M. Lessl -- Is there a human nature? : an argument against modern excarnation / Jean Bethke Elshtain -- Crossing frontiers of science : trespassing into a godless space, or, Fulfilling our manifest destiny / Leah Ceccarelli -- The angels and devils of representing Prozac / Tod Chambers -- "Leave your medicine outside" : bioethics, spirituality, and the rhetoric of Appalachian serpent handlers / Bill J. Leonard -- Biovaluable stories and a narrative ethics of reconfigurable bodies / Arthur W. Frank -- Blacks and the language of their biotechnological future / Ezra E. H. Griffith -- Bioethics, economism, and the rhetoric of technological innovation / Howard Brody -- Technologies of the self at the end of life : pastoral power and the rhetoric of advance care planning / Lisa Kernen -- Suffering and the rhetoric of care / Judy Segal.
  • 2015 Springer Protocols
    Fulltext v. 2 (2015) Springer Protocols
    edited by Kan Wang, Center for Plant Transformation, Plant Sciences Institute, and Department of Agronomy, Iowa State University, Ames, IA, USA.
    Volume 1. Gateway®-compatible plant transformation vectors /Mark A. Smedley and Wendy A. Harwood -- Brachypodium distachyon /Jennifer N. Bragg ... [et al.] -- Medicago truncatula transformation using cotyledonary explants /Elane Wright and Zeng-Yu Wang -- Medicago truncatula transformation using leaf explants /Viviane Cosson, Alexis Eschstruth , and Pascal Ratet -- Setaria viridis /Joyce Van Eck and Kerry Swartwood -- Barley (Hordeum vulgare L.) transformation using immature embryos /Cornelia Marthe, Jochen Kumlehn, and Goetz Hensel -- Barley (Hordeum vulgare L.) transformation using embryogenic pollen cultures /Ingrid Otto, Andrea Müller, and Jochen Kumlehn -- Maize (Zea mays L.) /Bronwyn Frame ... [et al.] -- Maize, tropical (Zea mays L.) /Shireen K. Assem -- Finger millet [Eleusine coracana (L.) Gaertn.] /Stanislaus Antony Ceasar and Savarimuthu Ignacimuthu -- Oat (Avena sativa L.) /Sebastian Gasparis and Anna Nadolska-Orczyk -- Rice, indica (Oryza sativa L.) /Yukoh Hiei, Yuji Ishida, and Toshihiko Komari -- Rice, japonica (Oryza sativa L.) /Marcy Main, Bronwyn Frame, and Kan Wang -- Sorghum (sorghum bicolor ) /Xiaomei Guo, Zhengxiang Ge, Shirley J. Sato, and Tom E. Clemente -- Wheat (Triticum aestivum L.) transformation using immature embryos /Yuji Ishida ... [et al.] -- Wheat (Triticum aestivum L.) transformation using mature embryos /Eva Medvecká and Wendy A. Harwood -- Alfalfa (Medicago sativa L.) /Chunxiang Fu ... [et al.] -- Clovers (Trifolium spp.) /Samira Rahimi-Ashtiani ... [et al.] -- Clover, red (Trifolium pratense) /Michael L. Sullivan and Kenneth H. Quesenberry -- Cowpea [Vigna unguiculata (L.) walp.] /Ratikanta Behura ... [et al.] -- Lentil (Lens culinaris medik) /Ufuk Celikkol Akcay, Meral Yücel, and Hüseyin Avni Öktem -- Soybean [Glycine max (L.) Merr.] /Diane Luth, Katey Warnberg, and Kan Wang -- Brassica oleracea and B. napus /Penny A. C. Hundleby née Sparrow and Judith A. Irwin -- Cucumber (Cucumis sativus L.) and kabocha squash (Cucurbita moschata Duch) /Yoshihiko Nanasato and Yutaka Tabei -- Pepper, chili (Capsicum annuum) /Jung Min ... [et al.] -- Pepper, sweet (Capsicum annuum) /Iris Heidmann and Kim Boutilier -- Sugar beet (Beta vulgaris L.) /Hiroyo Kagami ... [et al.] -- Tomato (Solanum lycopersicum) /Dora Garcia, Javier Narváez-Vásquez, and Martha L. Orozco-Cárdenas.
  • 2009 Springer
    Bernd H. A. Rehm, editor.
  • 2015
    written by Liz Richardson.
    Recent initiatives have sought to close gaps between the two federal agencies' medical technology evaluation processes.
  • 2008 Springer
    edited by B. Andrew Lustig, Baruch A. Brody, Gerald P. McKenny.
  • 2012 Springer Protocols
    edited by Beth Shapiro, Michael Hofreiter.
    Setting up an ancient DNA laboratory / Tara L. Fulton -- A phenol-chloroform protocol for extracting DNA from ancient samples / Ross Barnett and Greger Larson -- DNA extraction of ancient animal hard tissue samples via adsorption to silica particles / Nadin Rohland -- Case study : recovery of ancient nuclear DNA from toe pads of the extinct passenger pigeon / Tara L. Fulton, Stephen M. Wagner, and Beth Shapiro -- Extraction of DNA from paleofeces / Melanie Kuch and Hendrik Poinar -- DNA extraction from keratin and chitin / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient sloth DNA recovered from hairs preserved in paleofeces / Andrew A. Clack, Ross D.E. MacPhee, and Hendrik N. Poinar -- Ancient DNA extraction from soils and sediments / James Haile -- DNA extraction from fossil eggshell / Charlotte L. Oskam and Michael Bunce -- Ancient DNA extraction from plants / Logan Kistler -- DNA extraction from formalin-fixed material / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient DNA recovered from Pleistocene-age remains of a Florida armadillo / Brandon Letts and Beth Shapiro -- Nondestructive DNA extraction from museum specimens / Michael Hofreiter -- Case study : using a nondestructive DNA extraction method to generate mtDNA sequences from historical chimpanzee specimens / Elmira Mohandesan, Stefan Prost, and Michael Hofreiter -- PCR amplification, cloning, and sequencing of ancient DNA / Tara L. Fulton and Mathias Stiller -- Quantitative real-time PCR in aDNA research / Michael Bunce, Charlotte L. Oskam, and Morten E. Allentoft -- Multiplex PCR amplification of ancient DNA / Mathias Stiller and Tara L. Fulton -- Preparation of next-generation sequencing libraries from damaged DNA / Adrian W. Briggs and Patricia Heyn -- Generating barcoded libraries for multiplex high-throughput sequencing / Michael Knapp, Mathias Stiller, and Matthias Meyer -- Case study : targeted high-throughput sequencing of mitochondrial genomes from extinct cave bears via direct multiplex PCR sequencing (DMPS) / Mathias Stiller -- Target enrichment via DNA hybridization capture / Susanne Horn -- Case study : enrichment of ancient mitochondrial DNA by hybridization capture / Susanne Horn -- Analysis of high-throughput ancient DNA sequencing data / Martin Kircher -- Phylogenetic analysis of ancient DNA using BEAST / Simon Y.W. Ho.
  • 2013 Springer
    Shaker A. Mousa, Paul J. Davis, editors.
    This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.
  • 2014 ScienceDirect
    edited by Ashish S. Verma, Anchal Singh.
    Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field. Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases. Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering.
  • 2007 Springer Protocols
    edited by Ralf Pörtner.
  • 2014 Springer Protocols
    edited by Ralf Pörtner.
    High-throughput synchronization of mammalian cell cultures by spiral microfluidics / Wong Cheng Lee, Ali Asgar S. Bhagat, and Chwee Teck Lim -- Insect cell line development using Flp-mediated cassette exchange technology / João Vidigal ... [et al.] -- Scalable transient gene expression in adherent mammalian cells using polyethylenimine / Lukas Fliedl and Christian Kaisermayer -- Scalable transient protein expression / Henry C. Chiou ... [et al.] -- DNA profiling and characterization of animal cell lines / Glyn N. Stacey, Ed Byrne, and J. Ross Hawkins -- Tools for high-throughput process and medium optimization / Martin Jordan and Matthieu Stettler -- Designing media for animal cell culture : CHO cells, the industrial standard / Karlheinz Landauer -- Feed optimization in fed-batch culture / Ana Rita Costa ... [et al.] -- Screening and optimization of chemically defined media and feeds with integrated and statistical approaches / Zhihua Xiao ... [et al.] -- Evaluation of solid and porous microcarriers for cell growth and production of recombinant proteins / Maria Elisa Rodrigues ... [et al.] -- Microbioreactors and scale-down models : growth of CHO cells using the pall micro24 microreactor system / Steve R.C. Warr -- Monitoring cell growth, viability, and apoptosis / Michael Butler, Maureen Spearman, and Katrin Braasch -- Metabolic flux estimation in mammalian cell cultures / Chetan T. Goudar ... [et al.] -- Quenching methods for the analysis of intracellular metabolites / Judith Wahrheit and Elmar Heinzle -- NMR methods for metabolomics of mammalian cell culture bioreactors / Nelly Aranibar and Michael D. Reily -- ¹H-NMR protocol for exometabolome analysis of cultured mammalian cells / Tiago M. Duarte ... [et al.] -- Microfluidic perfusion culture / Koji Hattori, Shinji Sugiura, and Toshiyuki Kanamori -- Disposable bioreactors for inoculum production and protein expression / Regine Eibl, Christian Löffelholz, and Dieter Eibl -- Configuration of bioreactors / Dirk E. Martens, Evert J.van den End, and Mathieu Streefland -- Process analytical technology (PAT) in insect and mammalian cell culture processes : dielectric spectroscopy and focused beam reflectance measurement (FBRM) / Damir Druzinec ... [et a.] -- Cell assessment by at-line microscopy / Alexander Babitzky, Patrick Lindner, and Thomas Scheper -- Seed train optimization for cell culture / Björn Frahm -- Vaccine production : upstream processing with adherent or suspension cell lines / Yvonne Genzel ... [et al.] -- Efficient processes for protein expression using recombinant baculovirus particles / Heike Cremer ... [et al.] -- Chromatographic techniques in the downstream processing of proteins in biotechnology / Ruth Freitag -- Virus separation using membranes / Tanja A. Grein, Ronald Michalsky, and Peter Czermak.
  • 2006 Springer
    edited by Shinji Iijima and Ken-ichi Nishijima.
  • 2009 Springer
    Koji Ikura ... [et al.], editors.
  • 2012 Springer
    Thomas J. Dougherty, Michael J. Pucci, editors.
  • 2012 Springer Protocols
    edited by Patrick Chames.
    1. Use of IMGT® databases and tools for antibody engineering and humanization / Marie-Paule Lefranc, Franc̦ois Ehrenmann, Chantal Ginestoux, Véronique Giudicelli, and Patrice Duroux -- 2. Computer-assisted modeling of antibody variable domains / Oscar H.P. Ramos -- 3. Cloning single-chain antibody fragments (scFv) from hyrbidoma cells / Lars Toleikis and André Frenzel -- 4. Human in-cell scFv library from infiltrating B cell / Sylvie Peraldi-Roux -- 5. Construction of human naive antibody gene libraries / Michael Hust, Andreí Frenzel, Torsten Meyer, Thomas Schirrmann, and Stefan Dübel -- 6. Synthetic customized scFv libraries / Gautier Robin and Pierre Martineau -- 7. Selection of stable scFv antibodies by phage display / Eeva-Christine Brockmann -- 8. Generation of single domain antibody fragments derived from camelids and generation of manifold constructs / Cécile Vincke, Carlos Gutiérrez, Ulrich Wernery, Nick Devoogdt, Gholamreza Hassanzadeh-Ghassabeh, and Serge Muyldermans -- 9. Generation and isolation of target-specific single-domain antibodies from shark immune repertoires / Mischa Roland Müller, Ronan O'Dwyer, Marina Kovaleva, Fiona Rudkin, Helen Dooley, and Caroline Jane Barelle -- 10. Generation of human single domain antibody repertoires by Kunkel mutagenesis / Romain Rouet, Kip Dudgeon, and Daniel Christ -- 11. Phage display and selections on purified antigens / Julie Matz and Patrick Chames -- 12. Phage display and selections on cells / Klervi Even-Desrumeaux and Patrick Chames -- 13. Humanization by CDR grafting and specificity-determining residue grafting / Jin Hong Kim and Hyo Jeong Hong -- 14. Humanization by guided selections / Sang Jick Kim and Hyo Jeong Hong -- 15. Selection of antibody fragments by yeast display / Nathalie Scholler -- 16. Evolution of antibodies in vitro by ribosome display / Bryan M. Edwards and Mingyue He -- 17. Mammalian cell surface display of full length IgG / Chen Zhou and Wenyan David Shen -- 18. Production of antibody fragments in Escherichia coli / Tomohisa Katsuda, Hiroyuki Sonoda, Yoichi Kumada -- 19. Production of antibody derivatives in the methylotrophic yeast Pichia pastoris / Steve Schoonooghe, Jannick Leoen, and Jurgen Haustraete -- 20. Monoclonal antibody expression in mammalian cells / Richard Yi Zhang and Wenyan David Shen -- 21. Production of recombinant antibodies in Drosophila melanogaster S2 cells / Daniel X. Johansson, Thomas Krey, and Oskar Andersson -- 22. Production of antibody fragments using the baculovirus-insect cell system / Takanori Furuta, Takafumi Ogawa, and Hideki Yamaji -- 23. Transient and stable expression of antibodies in Nicotiana species / Freydoun Garabagi, Michael D. McLean, and J. Christopher Hall -- 24. Measuring antibody-antigen binding kinetics using surface plasmon resonance / Stephen Hearty, Paul Leonard, and Richard O'Kennedy -- 25. Affinity determination of biotinylated antibodies by flow cytometry / Klervi Even-Desrumeaux and Patrick Chames -- 26. Affinity maturation of antibodies : optimized methods to generate high-quality scFv libraries and isolate IgG candidates by high-throughput screening / Laurence Renaut, Céline Monnet, Olivier Dubreuil, Ouafa Zaki, Fabien Crozet, Khalil Bouayadi, Hakim Kharrat, and Philippe Mondon -- 27. Affinity maturation by semi-rational approaches / Rodrigo Barderas, Johan Desmet, Philippe Alard, and J. Ignacio Casal -- 28. Molecular scanning : combining random mutagenesis, ribosome display, and bioinformatic analysis for protein engineering / Alfredo Darmanin-Sheehan, William James Jonathan Finlay, Orla Cunningham, and Brian Joseph Fennell -- 29. Fucose-targeted glycoengineering of pharmaceutical cell lines / Christiane Ogorek, Ingo Jordan, Volker Sandig, and Hans Henning von Horsten -- 30. Fc engineering : design, expression, and functional characterization of antibody variants with improved effector function / Stefanie Derer, Christian Kellner, Sven Berger, Thomas Valerius, and Matthias Peipp -- 31. Fc engineering : serum half-life modulation through FcRn binding / Tove Olafsen -- 32. Monoclonal antibody lead characterization : in vitro and in vivo methods / Axel Hernandez, Julie Parmentier, Youzhen Wang, Jane Cheng, and Gadi Gazit Bornstein -- 33. Production, purification, and characterization of scFv TNF ligand fusion proteins / Andrea Fick, Agnes Wyzgol, and Harald Wajant --34. Antibody-IL2 fusion proteins for tumor targeting / Andreas A. Hombach and Hinrich Abken -- 35. Recombinant immunotoxins with low endotoxins for clinical and animal studies / Masanori Onda -- 36. Chimeric antigen receptors for T-cell based therapy / Eleanor J. Cheadle, Vicky Sheard, Andreas A. Hombach, Markus Chmielewski, Tobias Riet, Cor Berrevoets, Erik Schooten, Cor Lamers, Hinrich Abken, Reno Debets, and David E. Gilham -- 37. Selection and use of intracellular antibodies (intrabodies) / Sandrine Moutel, Clément Nizak, and Franck Perez -- 38. Radiolabeled antibodies for cancer imaging and therapy / Jacques Barbet, Manuel Bardiès, Mickael Bourgeois, Jean-Franc̦ois Chatal, Michel Chérel, Franc̦ois Davodeau, Alain Faivre-Chauvet, Jean-Franc̦ois Gestin, and Franc̦oise Kraeber-Bodéré -- 39. Design and production of multimeric antibody fragments, focused on diabodies with enhanced and clinical efficacy / Glenn A. Powers, Peter J. Hudson, and Michael P. Wheatcroft -- 40. Production of bispecific antibodies : diabodies and tandem scFv / Nora Hornig and Aline Färber-Schwarz.
  • v. 1-2, 2010. Springer
    v. 2, 2010 Springer
    Roland Kontermann, Stefan Dübel (editors).
  • 2011 Springer
    edited by Mohamed Al-Rubeai.
    Engineered antibodies currently represent over 30 per cent of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the generation, optimization, characterization, production and applications of antibody. It provides the necessary theoretical background and description of methods for the expression of antibody in.
  • 2015 Springer
    G.M. Anantharamaiah, Dennis Goldberg, editors.
  • 2011 Springer
    Kewal K. Jain.
  • 2013 Springer
    Kewal K. Jain.
    Culling together excerpts from a wide range of writings by Dr. Kewal K. Jain on biotechnology topics as they relate to disorders of the nervous system, Applications of Biotechnology in Neurology covers a variety of applications for those working in life sciences and the pharmaceutical sciences, particularly those developing diagnostics and therapeutics for the nervous system. This detailed volume delves into areas such as neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, various methods of improving systemic administration of drugs for targeted delivery to the nervous system, including the use of nanobiotechnology, biotechnology-based strategies and products for neuroprotection, as well as chapters on neurosurgery and personalized neurology.
  • 2014 Springer
    Kewal K. Jain.
    Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various -omics technologies and their application in oncology are described as oncogenomics and oncoproteomics. This detailed volume also explores molecular diagnostics, nanobiotechnology, cell and gene therapies, as well as personalized oncology. With approximately one thousand selected references from recent literature on this topic and numerous tables and figures, Applications of Biotechnology in Oncology serves as an ideal reference for oncologists, scientists involved in research on cancer biology, and physicians in various specialties who deal with cancer.
  • 2007 Springer
    edited by R. Verpoorte, A.W. Alfermann and T.S. Johnson.
    Biosynthesis of plant natural products and characterization of plant biosynthetic pathways in recombinant microorganisms / Erin K. Marasco, Claudia Schmidt-Dannert -- Plant molecular farming: host systems, technology and products / G.B. Sunil Kumar ... [et al.] -- Plastid pathways: metabolic engineering via the chloroplast genom / Tracey Ruhlman, Henry Daniell -- Metabolic engineering of the alkaloid biosynthesis in plants: functional genomics approaches / Kirsi-Marja Oksman-Caldentey, Suvi T. Häkkinen, Heiko Rischer -- Polyamine biosynthetic pathway: a potential target for enhancing alkaloids production: polyamines in alkaloid production / Esha Bhattacharya, M.V.Rajam -- Metabolic engineering in alkaloid biosynthesis: case studies in tyrosine- and putrescine-derived alkaloids: molecular engineering in alkaloid biosynthesis / Fumihiko Sato, Koji Inai, Takashi Hashimoto -- Application of metabolic engineering to vanillin biosynthetic pathways in Vanilla planifolia / Daphna Havkin-Frenkel, Faith C. Belanger -- Pathway engineering of the plant Vitamin C metabolic network / Argelia Lorence, Craig L. Nessler -- Metabolic engineering of terpenoid biosynthesis in plants / Joost Lücker, Harro J. Bouwmeester, Asaph Aharoni -- Metabolic engineering of seed oil biosynthetic pathways for human health / Howard G. Damude, Anthony J. Kinney -- Metabolic engineering in sugarcane: assisting the transition to a bio-based economy / Robert G. Birch -- Single-chain Fv antibody stimulates biosynthesis of secondary metabolites in plants / Waraporn Putalun, Hiroyuki Tamaka, Yukihiro Shoyama -- Metabolic engineering of sulfur assimilation in plants : molecular and biochemical analysis of serine acetyltransferase and cysteine synthase / Masaaki Noji, Kazuki Saito -- Approaches to quality plant based medicine: significance of chemical profiling / Praveen K. Saxena, Ian B. Cole, Susan J. Murch.
  • 2006 ScienceDirect
    edited by Dilip K. Arora, Randy M. Berka, Gautam B. Singh.
    The advances in genomic technologies, such as microarrays and high throughput sequencing, have expanded the realm of possibilities for capturing data and analyzing it using automated computer driven bioinformatics tools. With the completion of the sequencing of genomes of human and several model organisms, a quest for scientific discoveries being fueled by integrative and multidimensional techniques in mathematics and computational sciences. In this volume, leading researchers and experts have provided an overview of significant concepts from biological, mathematical, and computational perspectives. It provides a high level view of fungal genomic data integration and annotation, classification of proteins and identification of vaccine targets, identification of secretome or secreted proteins in fungal genomes, as well as tools for analyzing microarray expression profiles. * Provides a survey of theoretical underpinnings on the technological tools and applications * Discusses the tools utilized for the annotation of fungal genomes and addresses issues related to automated annotation generation in a high throughput biotechnology environment * describing the applications of the concepts and methodologies presented throughout the book.
  • 2010 CRCnetBASE
    Roger L. Lundblad.
    Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules -- Light scattering and biomacromolecular conformation -- Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products -- Near-infrared spectroscopy and macromolecular conformation -- Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules -- Use of Raman spectroscopy to evaluate biopharmaceutical conformation -- The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products -- Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation -- Use of nuclear magnetic resonance for the characterization of biotherapeutic products -- Use of chemical probes for the study of protein conformation -- Use of hydrogen exchange in the study of biopharmaceutical conformation -- Use of chemical modification for the conformational analysis of biopharmaceuticals -- Use of immunology to characterize biopharmaceutical conformation -- Use of limited proteolysis to study the conformation of proteins of biotechnological interest -- Other technologies for the characterization of conformational change in biopharmaceuticals -- Development of an experimental approach for the study of the conformation of a biological therapeutic product.
  • 2008 CRCnetBASE
    edited by Stephen A. Osmani, Gustavo H. Goldman.
  • 2012 Springer
    Michal Amit, Joseph Itskovitz-Eldor ; with contributions by Ilana Laevsky and Atara Novak.
  • 2014 Springer
    Marco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero.
    β-barrel outer membrane channel proteins (OMP) have great potential as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties without affecting the overall protein structure and stability. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. The β-barrel structure serviceability for the nano-material design will be its chief topic giving a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel to be adapted to a non-biological synthetic (i.e. polymer) environment, rendering it competitive with artificial non-biological nano-pores will be outlined specifically the design of a set of protein nano-channels with tailored geometry (diameter, length), conductance and functionality will be reported as a case study. In order to make this book a valuable source of information for both biotechnologists and other scientists interested in bio-nanotechnology an overview of the different steps involved in the nano-channel protein design and production will be reported. The scientific strategy from concept design, theoretical considerations, genetic engineering and large scale production, to system assembly and biophysical characterization with an overview on technological applications including membrane/polymersome technology, will be described.
    Also available: Print – 2014
  • 2007 Springer
    Rainer Huopalahti ... [et al.] (eds.).
  • 2007 Springer
    edited by Warren C.W. Chan.
    Synthetic strategies to size and shape controlled nanocrystals and nanocrystal heterostructures / P. Davide Cozzoli and Liberato Manna -- Current approaches for engineering proteins with diverse biological properties / Isaac T.S. Li, Elizabeth Pham, and Kevin Truong -- Past, present, and future of gold nanoparticles / Travis Jennings and Geoffrey Strouse -- Multi-functional gold nanoparticles for drug delivery / Gang Han, Partha Ghosh, and Vincent M. Rotello -- Quantum dots for cancer molecular imaging / Xiaohu Gao and Shivang R. Dave -- Carbon nanostructures as a new high-performance platform for MR molecular imaging / Keith B. Hartman and Lon J. Wilson -- Magnetic nanoparticle assisted molecular MR imaging / Young-wook Jun, Jung-tak Jang, and Jinwoo Cheon -- Patterning metallic nanoparticles by DNA scaffolds / Rahul Chhabra ... [et al.] -- Liposomes in biology and medicine / Reto A. Schwendener -- Fluorescent nanoparticle for bacteria and DNA detection / Wenjun Zhao, Lin Wang, and Weihong Tan -- Dendrimer 101 / Lajos P. Balogh -- Quantum dots and other fluorescent nanoparticles: quo vadis in the cell? / Dusica Maysinger and Jasmina Lovri -- Toxicity studies of fullerenes and derivatives / Jelena Kolosnjaj, Henri Szwarc, and Fathi Moussa -- Toxicity studies of carbon nanotubes / Jelena Kolosnjaj, Henri Szwarc, and Fathi Moussa.
    Also available: Print – 2007
  • 2015 Springer
    Amy Rosenberg, Barthélemy Demeule, editors.
  • 2007 CRCnetBASE
    edited by Ramesh N. Patel.
    ch. 1. Nitrilases and nitrile hydratases / Robert DiCosimo -- ch. 2. Biocatalytic deracemization : dynamic resolution, stereoinversion, enantioconvergent processes, and cyclic deracemization / Yolanda Simeo, Wolfgang Kroutil, and Kurt Faber -- ch. 3. A decade of biocatalysis at Glaxo Wellcome / Mahmoud Mahmoudian -- ch. 4. Biocatalysis for synthesis for chiral pharamaceutical intermediates / Ramesh N. Patel -- ch. 5. Directed evolution of lipases and esterases for organic synthesis / Aurelio Hidalgo and Uwe T. Bornscheuer -- ch. 6. Flavin-containing oxidative biocatalysts / Marco W. Fraaije and Willem J.H. van Berkel -- ch. 7. Preparation of chiral pharmaceuticals through enzymatic acylation of alcohols and amines / Vicente Gotor-Fernandez, Francisca Rebolledo, and Vicente Gotor -- ch. 8. Dynamic kinetic resolution and asymmetric transformations by enzyme-metal combinations / Mahn-Joo Kim, Yangsoo Ahn, and Jaiwook Park -- ch. 9. Biotransformation of natural or synthetic compounds for the generation of molecular diversity / Robert Azerad -- ch. 10. Applications of aromatic hydrocarbon dioxygenases / Rebecca E. Parales and Sol M. Resnick -- ch. 11. A genomic approach to investigating baker's yeast reductions / Jon D. Stewart -- ch. 12. Immobilization of enzymes as cross-linked enzyme aggregates : a simple method for improving performance / Roger A. Sheldon -- ch. 13. Biotechnological applications of aldolases / Wolf-Dieter Fessner and Stefan Jennewein -- ch. 14. Enzymatic synthesis of modified nucleosides / Luis A. Condezo ... [et al.] -- ch. 15. Biocatalytic reduction of carbozylic acids : mechanism and applications / Padmesh Venkitasubramanian, Lacy Daniels, and John P.N. Rosazza -- ch. 16. Dehalogenases in biodegradation and biocatalysis / Dick B. Janssen -- ch. 17. Enzymatic synthesis of sugar esters and oligosaccharides from renewable resources / A. Ballestros ... [et al.] -- ch. 18. Efficient methods and instrumentation for engineering custom enzymes / Steven J. Robles, William J. Coleman, and Mary M. Yang -- ch. 19. Deaminating enzymes of the purine cycle as biocatalysts for chemoezymatic synthesis and transformation of antiviral agents structurally related to purine nucleosides / Enzo Santaniello, Pierangela Ciuffreda, and Laura Alessandrini -- ch. 20. Mircobial and enzymatic processes for the production of chiral compounds / Kohsuke Honda ... [et al.] -- ch. 21. Discovery of arylmalonate decarbozylase and conversion of the function by rational design / Kenji Miyamoto and Hiromichi Ohta -- ch. 22. Chemoenzymatic preparation of enantiopure building blocks of synthetic utility / Kenji Mori -- ch. 23. Stereoselective modifications of polyhydorxylated steroids / Elena Fossati and Sergio Riva -- ch. 24. Recent developments in enzymatic acyloin condensations / Owen Ward and Ajay Singh -- ch. 25. Synthesis of chiral alcohols with carbonyl reductase library and robust NAD(P)H regenerating system / Hiroaki Yamamoto and Akinobu Matsuyama -- ch. 26. Comparative analysis of chemical and biocatalyic syntheses of drug intermediates / Michael J. Homann ... [et al.] -- ch. 27. Industrial processes using lyases fo C-C, C-N, and C-O bond formation / Martina Pohl an Andreas Lieses -- ch. 28. State of the art and applications in stereoselective synthesis of chiral cyanohydrins / Franz Effenberger, Siegfried Forster, and Christoph Kobler -- ch. 29. Chiral switches : problems, strategies, opportunities, and experiences / Rene Csuk -- ch. 30. Enzyme evolution for chemical process applications / Gjalt W. Huisman and James J. Lalonde -- ch. 31. Biocatalytic routes to nonracemic chiral amines / Nicholas J. Turner and Reuban Carr -- ch. 32. Enantioselective biocatalytic reduction of ketones for the synthesis of optically active alcohols / Stefan Buchholz and Harald Groger -- ch. 33. Enyzmes catalysis in nonaqueous media : past, present and future / Susanne Dreyer ... [et al.] -- ch. 34. Biocatalyic concepts for the synthesis of optically active amines / Stefan Buchholz and Harald Groger.
  • 2015
    editors, Paul G. Yock, Stefanos Zenios, Joshua Makower, Todd J. Brinton, Uday N. Kumar, F.T. Jay Watkins ; principal writer, Lyn Denend ; specialy editor, Thomas M. Krummel ; web editor, Christina Kurihara.
    "This step-by-step guide to medical technology innovation, now in full color, has been rewritten to reflect recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads students, researchers, and entrepreneurs through a proven process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. A wealth of additional material supports the book, including a collection of nearly 100 videos created for the second edition, active links to external websites, supplementary appendices, and timely updates on the companion website at ebiodesign.org. Readers can access this material quickly, easily, and at the most relevant point in the text from within the ebook"--Provided by publisher.
  • 2010 Springer
    edited by Maria Teresa Giardi, Giuseppina Rea, Bruno Berra.
    The Nutra-Snacks project : basic research and biotechnological programs on nutraceutics / Giuseppina Rea ... [et al.] -- Overview of diet-gene interactions and the example of xanthophylls / Barbara Demmig-Adams and William W. Adams III -- Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders / Giovanni Scapagnini, Calogero Caruso, and Vittorio Calabrese -- Plant phenolics in the prevention and treatment of cancer / Klaus W.J. Wahle ... [et al.] -- Endogenous antioxidants and radical scavengers / Angela Maria Rizzo ... [et al.] -- A nutritional strategy for reducing disease and obesity risks / Teresa Lavecchia ... [et al.] -- Dietary phytochemicals and human health / Justyna Krzyzanowska, Anna Czubacka, and Wieslaw Oleszek -- Bioactive compounds from northern plants / Anja Hohtola -- Nutraceutical use of garlic sulfur-containing compounds / Eleftherios Touloupakis and Demetrios F. Ghanotakis -- Genetic engineering to enhance crop-based phytonutrients (nutraceuticals) to alleviate diet-related diseases / Autar K. Mattoo ... [et al.] -- Perspective for the use of genetic transformants in order to enhance the synthesis of the desired metabolites : engineering chloroplasts of microalgae for the production of bioactive compounds / Udo Johanningmeier and Dirk Fischer -- Biological elicitors of plant secondary metabolites : mode of action and use in the production of nutraceutics / Simone Ferrari -- Hairy root cultures for secondary metabolites production / Laura Pistelli ... [et al.] -- Plant tissue culture : an opportunity for the production of nutraceuticals / Mariella Lucchesini and Anna Mensuali-Sodi -- Plant cell cultures : bioreactors for industrial production / Barbara Ruffoni ... [et al.] -- Determination of the antioxidants' ability to scavenge free radicals using biosensors / Montserrat Cortina-Puig ... [et al.] -- Biosensors for the determination of phenolic metabolites / Simona Carmen Litescu, Sandra Eremia, and Gabriel Lucian Radu -- Methods for the determination of antioxidant capacity in food and raw materials / Simona Carmen Litescu, Sandra Eremia, and Gabriel Lucian Radu -- Analytical methods for the extraction and identification of secondary metabolite production in 'in vitro' plant cell cultures / Alessandra Bertoli ... [et al.] -- Biosensors for functional food safety and analysis / Teresa Lavecchia, Arianna Tibuzzi, and Maria Teresa Giardi -- Biosensors for secondary metabolites, two case studies : ochratoxin A and microcystin / Monica Campàs, Beatriz Prieto-Simón And Régis Rouillon -- Biosensors as analytical tools in food fermentation industry / Lise Barthelmebs ... [et al.] -- An overview of the functional food market : from marketing issues and commercial players to future demand from life in space / Francesca Vergari, Arianna Tibuzzi, and Giovanni Basile -- Legislation on nutraceuticals and food supplements a comparison between regulations in USA and EU / Roberto Giunta, Giovanni Basile, and Arianna Tibuzzi.
    Also available: Print – 2010
  • 2012 Wiley
    [edited by] Julian Jones and Alexis G. Clare.
    The unique nature of glass / Alexis G. Clare -- Melt derived bioactive glass / Matthew D. O'Donnell -- Sol-gel derived glasses for medicine / Julian R. Jones -- Phosphate glasses / Delia S. Brauer -- The structure of bioactive glasses and their surfaces / Alastair N. Cormack -- Bioactive borate glasses / Steven B. Jung -- Glass-ceramics / Wolfram H'land -- Bioactive glass- and glass-ceramic coatings / Enrica Vern -- Composites containing bioactive glass / Aldo R. Boccaccini and Qi-Zhi Chen -- Inorganic-organic sol-gel hybrids / Yuki Shirosaki [and others] -- Dental applications of glasses / Leena Hupa and Antti Yli-Urpo -- Bioactive glass as synthetic bone grafts and scaffolds for tissue engineering / Julian R. Jones -- Glasses for radiotherapy / Delbert E. Day.
  • 2013
    Jorge L. Contreras and A. James Cuticchia, editors.
    "The book begins with an overview of the evolving bioinformatics field then explores legal issues surrounding the software tools that enable large-scale computational biology, including procurement and licensing of commercial software systems, in-house and contracted software development and issues surrounding open source software. Legal issues associated with software tools for large-scale computational biology are examined, including procurement and licensing of commercial software systems, in-house and contracted software development, and open source software." -- [Publisher-supplied data]
  • 2012 Springer Protocols
    edited by Michael E. Himmel.
    Challenges for assessing the performance of biomass degrading biocatalysts / Michael E. Himmel, Stephen R. Decker, and David K. Johnson -- Overview of computer modeling of cellulose / Malin Bergensträhle-Wohlert and John W. Brady -- Imaging cellulose using atomic force microscopy / Shi-You Ding and Yu-San Liu -- Preservation and preparation of lignocellulosic biomass samples for multi-scale microscopy analysis / Bryon S. Donohoe, Peter N. Ciesielski, and Todd B. Vinzant -- Coherent raman microscopy analysis of plant cell walls / Yining Zeng, Michael E. Himmel, and Shi-You Ding -- Immunological approaches to plant cell wall and biomass characterization : glycome profiling / Sivakumar Pattathil [and others] -- Immunological approaches to plant cell wall and biomass characterization : immunolocalization of glycan epitopes / Utku Avci, Sivakumar Pattathil, and Michael G. Hahn -- Method to evaluate biomass accessibility in wet state based on thermoporometry / Bon-Wook Koo and Sunkyu Park -- Cellulase processivity / David B. Wilson and Maxim Kostylev -- Simple method for determining specificity of carbohydrate-binding modules for purified and crude insoluble polysaccharide substrates / Oren Yaniv [and others] -- Bacterial cadherin domains as carbohydrate binding modules : determination of affinity constants to insoluble complex polysaccharides / Milana Fraiber [and others] -- Affinity electrophoresis as a method for determining substrate-binding specificity of carbohydrate-active enzymes for soluble polysaccharides / Sarah Moraïs, Raphael Lamed, and Edward A. Bayer -- Single-molecule tracking of carbohydrate-binding modules on cellulose using fluorescence microscopy / Yu-San Liu, Shi-You Ding, and Michael E. Himmel -- Bioprospecting metagenomics for new glycoside hydrolases / Jack Gilbert [and others] -- Anaerobic high-throughput cultivation method for isolation of thermophiles using biomass-derived substrates / Scott D. Hamilton-Brehm [and others] -- Assessing the protein concentration in commercial enzyme preparations / William S. Adney [and others] -- Reducing the effect of variable starch levels in biomass recalcitrance screening / Stephen R. Decker [and others] -- Analysis of transgenic glycoside hydrolases expressed in plants : T. reesei CBH I and A. cellulolyticus EI / Roman Brunecky [and others] -- Structural characterization of the heteroxylans from poplar and switchgrass / Koushik Mazumder [and others] -- Laser microdissection and genetic manipulation technologies to probe lignin heterogeneity and configuration in plant cell walls / Oliver R.A. Corea [and others] -- Lignin-degrading enzyme activities / Yi-ru Chen, Simo Sarkanen, and Yun-Yan Wang.
  • 2014 Cambridge
    2014 Knovel
    edited by Peter X. Ma, University of Michigan.
    "Written by world-leading experts, this book focusses on the role of biomaterials in stem cell research and regenerative medicine. Emphasising basic principles and methodology, it covers stem cell interactions, fabrication technologies, design principles, physical characterisation and biological evaluation, across a broad variety of systems and biomaterials. Topics include: stem cell biology, including embryonic stem cells, IPS, HSC and progenitor cells; modern scaffold structures, including biopolymer, bioceramic, micro- and nanofiber, ECM and biohydrogel; advanced fabrication technologies, including computer-aided tissue engineering and organ printing; cutting-edge drug delivery systems and gene therapy techniques; medical applications spanning hard and soft tissues, the cardiovascular system and organ regeneration. With a contribution by Nobel laureate Shinya Yamanaka, this is a must-have reference for anyone in the field of biomaterials, stem cell biology and engineering, tissue engineering and regenerative medicine"--Provided by publisher.
  • 2012 Springer
    Shuko Suzuki, Yoshito Ikada.
    1. Introduction -- 2. Biological Events Associated with Surgical Operation -- 3. Bioabsorbable Polymers -- 4. Sealants (Adhesives) to Prevent Bleeding -- 5. Barriers to Prevent Tissue Adhesion -- 6. Devices for Bone Fixation -- 7. Growth Factors for Promoting Wound Healing -- 8. Sutures for Wound Closure -- 9. Conclusions.
  • 2016 Springer
    Dominique G. Poitout, editor.
    I. Introduction -- II. Biocompatible Materials -- III. Tissue Biomechanics and Histomorphology -- IV. Biomechanics of Bone Growth -- V. Applications of Biomechanical Principles to Orthopedics and Traumatology -- VI. Applications of Biomechanics Principles to Oncology -- VII. Articular Biomechanics.
  • 2012 ebrary
    Edward Klees and H. Robert Horvitz.
    Issues to consider when negotiating a consulting agreement -- What constitutes consulting? -- Scope of services -- Cash compensation -- Shares, stock options, and taxes -- Confidentiality obligations -- IP rights -- Noncompetition -- Time commitment -- Term and termination -- Multiple relationships with one company -- Start-up issues -- Other clauses -- Use of consulting entity.
  • 2014 Cambridge
    Aly A. Farag.
    Overview of biomedical image analysis -- Overview of two-dimensional signals and systems -- Biomedical imaging modalities -- Random variables -- Random processes -- Basics of random fields -- Probability density estimation by linear models -- Basics of topology and computational geometry -- Geometric features extraction -- Variational approaches and level sets -- Segmentation -- statistical approach -- Segmentation -- variational approach -- Basics of registration -- Variational methods for shape registrations -- Statistical models of shape and appearance.
  • 2005 CRCnetBASE
    edited by Neelina H. Malsch.
    Converging technologies : nanotechnology and biomedicine / Mihail C. Roco -- Trends in biomedical nanotechnology programs worldwide / Mark Morrison and Ineke Malsch -- Nanotechnology and trends in drug delivery systems with self-assembled carriers / Kenji Yamamoto -- Implants and prostheses / Jeroen J.J.P. van den Beucken, X. Frank Walboomers, and John A. Jansen -- Diagnostics and high throughput screening / Aránzazu del Campo and Ian J. Bruce -- Nano-enabled components and systems for biodefense / Calvin Shipbaugh ... [et al.] -- Social and economic contexts : making choices in the development of biomedical nanotechnology / Ineke Malsch -- Potential risks and remedies / Emmanuelle Schuler.
    Also available: Print – 2005
  • 2010 Atypon
    Phillip Weinfurt.
    Evaluating biomedical technology poses a significant challenge in light of the complexity and rate of introduction in today's healthcare delivery system. Successful evaluation requires an integration of clinical medicine, science, finance, and market analysis. Little guidance, however, exists for those who must conduct comprehensive technology evaluations. The 3Q Method meets these present day needs. The 3Q Method is organized around 3 key questions dealing with 1) clinical and scientific basis, 2) financial fit and 3) strategic and expertise fit. Both healthcare providers (e.g., hospitals) and medical industry providers can use the Method to evaluate medical devices, information systems and work processes from their own perspectives. The book describes the 3Q Method in detail and provides additional suggestions for optimal presentation and report preparation.
  • 2010
    edited by Adele E. Clarke, Laura Mamo, Jennifer Ruth Fosket, Jennifer R. Fishman, Janet K. Shim.
    Biomedicalization : technoscientific transformations of health, illness, and U.S biomedicine / Adele E. Clarke, Janet K. Shim, Laura Mamo, Jennifer Ruth Fosket, and Jennifer R. Fishman -- Charting (bio)medicine and (bio)medicalization in the United States, 1890/present / Adele E. Clarke, Jennifer Ruth Fosket, Laura Mamo, Jennifer R. Fishman, and Janet K. Shim -- From the rise of medicine to biomedicalization : U.S. healthscapes and iconography, circa 1890/present / Adele E. Clarke -- Gender and medicalization and biomedicalization theories / Elianne Riska -- Fertility, Inc. : consumption and subjectification in U.S. lesbian reproductive practices / Laura Mamo -- The body as image : an examination of the economic and political dynamics of magnetic resonance imaging and the construction of difference / Kelly Joyce -- The stratified biomedicalization of heart disease : expert and lay perspectives on racial and class inequality / Janet K. Shim -- Marking populations and persons at risk : molecular epidemiology and environmental health / Sara Shostak -- Surrogate markers and surrogate marketing in biomedicine : the regulatory etiology and commercial progression of "ethnic" drug development / Jonathan Kahn -- The making of Viagra : the biomedicalization of sexual dysfunction / Jennifer R. Fishman -- Bypassing blame : bariatric surgery and the case of biomedical failure / Natalie Boero -- Breast cancer risk as disease : biomedicalizing risk / Jennifer Ruth Fosket -- Biopsychiatry and the informatics of diagnosis : governing mentalities / Jackie Orr.
  • 2012 Wiley
    edited by João F. Mano.
    Examples of natural and nature-inspired materials. Biomaterials from marine-origin biopolymers / Tiago H Silva, Ana R C Duarte, Joana Moreira-Silva, João F Mano, Rui L Reis -- Hydrogels from protein engineering / Midori Greenwood-Goodwin, Sarah C Heilshorn -- Collagen-based biomaterials for regenerative medicine / Christophe Helary, Abhay Pandit -- Silk-based biomaterials / Silvia Gomes, Isabel B Leonor, João F Mano, Rui L Reis, David L Kaplan -- Elastin-like macromolecules / Rui R Costa, Laura Martin, João F Mano, Jose C Rodriguez-Cabello -- Biomimetic molecular recognition elements for chemical sensing / Justyn Jaworski -- Surface aspects. Biology lessons for engineering surfaces for controlling cell-material adhesion / Ted T Lee, Andres J Garcia -- Fibronectin fibrillogenesis at the cell-material interface / Marco Cantini, Patricia Rico, Manuel Salmeron-Sanchez -- Nanoscale control of cell behavior on biointerfaces / E Ada Cavalcanti-Adam, Dimitris Missirlis -- Surfaces with extreme wettability ranges for biomedical applications / Wenlong Song, Natalia M Alves, João F Mano -- Bio-inspired reversible adhesives for dry and wet conditions / Aranzazu del Campo, Juan Pedro Fernandez-Blazquez -- Lessons from sea organisms to produce new biomedical adhesives / Elise Hennebert, Pierre Becker, Patrick Flammang -- Hard and mineralized systems. Interfacial forces and interfaces in hard biomaterial mechanics / Devendra K Dubey, Vikas Tomar -- Nacre-inspired biomaterials / Gisela M Luz, João F Mano -- Surfaces inducing biomineralization / Natalia M Alves, Isabel B Leonor, Helena S Azevedo, Rui L Reis, João F Mano -- Bioactive nanocomposites containing silicate phases for bone replacement and regeneration / Melek Erol, Jasmin Hum, Aldo R Boccaccini -- Systems for the delivery of bioactive agents. Biomimetic nanostructured apatitic matrices for drug delivery / Norberto Roveri, Michele Iafisco -- Nanostructures and nanostructured networks for smart drug delivery / Carmen Alvarez-Lorenzo, Ana M Puga, Angel Concheiro -- Progress in dendrimer-based nanocarriers / Joaquim M Oliveira, João F Mano, Rui L Reis -- Lessons from nature in regenerative medicine. Tissue analogs by the assembly of engineered hydrogel blocks / Shilpa Sant, Daniela F Coutinho, Nasser Sadr, Rui L Reis, Ali Khademhosseini -- Injectable -forming scaffolds for tissue engineering / Da Yeon Kim, Jae Ho Kim, Byoung Hyun Min, Moon Suk Kim -- Biomimetic hydrogels for regenerative medicine / Iris Mironi-Harpaz, Olga Kossover, Eran Ivanir, Dror Seliktar -- Bio-inspired 3d environments for cartilage engineering / Jose Luis Gomez Ribelles -- Soft constructs for skin tissue engineering / Simone S Silva, João F Mano, Rui L Reis.
  • 2012 Wiley
    edited by Matteo Santin, Gary Phillips.
    1. History of miomimetic, bioactive and bioresponse biomaterials -- 2. Soft tissue structure and functionality -- 3. Hard tissue structure and functionality -- 4. Biomedical applications of biomimetic polymers: the phosphorylcholine-containing polymers -- 5. Biomimetic, bioresponsive, and bioactive materials: integrating materials with tissue -- 6. Ceramics -- 7. Biofunctional biomaterials of the future.
  • 2006 CRCnetBASE
    edited by Yoseph Bar-Cohen.
  • 2013 Wiley
    edited by Murugan Ramalingam, Xiumei Wang, Guoping Chen, Peter Ma, and Fu-Zhai Cui.
    1. Biomimetic polysaccharides and derivatives for cartilage tissue regeneration -- 2. Biomimetic synthesis of self-assembled mineralized collagen-based composites for bone tissue engineering -- 3. Biomimetic mineralization of hydrogel biomaterials for bone tissue engineering -- 4. Biomimetic nanofibrous scaffolds for bone tissue engineering applications -- 5. Bioactive polymers and nanobiomaterials composites for bone tissue engineering -- 6. Strategy for a biomimetic paradigm in dental and craniofacial tissue engineering -- 7. Strategies to prevent bacterial adhesion on biomaterials -- 8. Nanostructured selenium- a novel biologically-inspired material for antibacterial medical device applications -- 9. Hydroxyapatite-biodegradable polymer nanocomposite microspheres toward injectable cell scaffold -- 10. Biomimetic ECM scaffolds prepared from cultured cells -- 11. Design and synthesis of phoreactive polymers for biomedical applications -- 12. The emerging applications of graphene oxide and graphene in tissue engineering -- 13. Biomimetic preparation and morphology control of mesoporous silica -- 14. Biomimetic materials for engineering stem cells and tissues.
  • 2007
    Jian-Qin Liu, Katsunori Shimohara.
  • 2013 Wiley
    edited by Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama, Fereidoon Shahidi.
    Nanotechnology / Hiroshi Muramatsu, Jun'ichi Wakayama, Kazumi Tsukamoto, Shigeru Sugiyama -- Applications of NMR to Biomolecular Systems of Interactions: An Overview / Shinya Hanashima, Yoshiki Yamaguchi -- Applications in Enhancing bioavailability and Controlling Pathogens. Bioavailability and Delivery of Nutraceuticals and Functional Foods Using Nanotechnology / Hailong Yu, Qingrong Huang -- Encapsulation of Bioactive Compounds in Micron/Submicron-Sized Dispersions Using Microchannel Emulsification or High-Pressure Homogenization / Marcos A Neves, Isao Kobayashi, Henelyta S Ribeiro, Katerina B Fujiu -- Nanometric-Size Delivery Systems for Bioactive Compounds for the Nutraceutical and Food Industries / Francesco Donsi, Mariarenata Sessa, Giovanna Ferrari -- Nanoemulsion Technology for Delivery of Nutraceuticals and Functional-Food Ingredients / Luz Sanguansri, Christine M Oliver, Fernando Leal-Calderon -- Nanotechnology and Nonpolar Active Compounds in Functional Foods: An Application Note / Philip J Bromley -- Safety, Toxicology and Regulatory Aspects. How Standards Inform the Regulation of Bio-nanotechnology / Martha E Marrapese -- FDA and Nanotech: Baby Steps Lead to Regulatory Uncertainty / Raj Bawa -- Toxicity and Environmental Risks of Nanomaterials: An Update / Paresh C Ray, Anant Kumar Singh, Dulal Senapati, Zhen Fan, Hongtao Yu -- Nanoparticle-Lung Interactions and Their Potential Consequences for Human Health / Craig A Poland, Martin J D Clift -- Future Directions in Bio-Nanotechnology Bio-Nanotechnology: A Journey Back to the Future / Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama, Fereidoon Shahidi.
  • 2009 CRCnetBASE
    edited by David E. Reisner.
  • 2006 Springer
    edited by V. Renugopalakrishnan and Randolph V. Lewis.
  • 2007
    Elisabeth S. Papazoglou, Aravind Parthasarathy.
  • 2013 CRCnetBASE
    editors, Victor R. Preedy, Vinood Patel.
    Functional optical imaging-based biosensors / Pablo Iglesias and Jose A. Costoya -- Use of a surface plasmon resonance (SPR) biosensor to characterize zwitterionic coatings on SiO2 for cancer biomarker detection / Norman D. Brault, Shaoyi Jiang, and Qiuming Yu -- Microcantilever-based biosensor array for tumor angiogenic marker detection / Riccardo Castagna and Carlo Ricciardi -- Electrochemical DNA biosensors at the nanoscale / Rosa Letizia Zaffino ... [et al.] -- Aptamer-based biosensors for cancer studies / Ilaria Palchetti and Marco Mascini -- Fluorescent biosensors for cancer cell imaging and diagnostics / May C. Morris -- Electrical and electrochemical immunosensor for cancer study / Seung Yong Lee and Seung Yong Hwang -- Multifunctional nanobiosensors for cancer / Dai-Wen Pang and Er-Qun Song -- Silicon nanowire biosensor for cancer markers / Yang-Kyu Choi and Chang-Hoon Kim -- DNA-electrochemical biosensors and oxidative damage to DNA : application to cancer / Victor Constantin Diculescu and Ana Maria Oliveira Brett -- Asparaginase-based asparagine biosensors and their application to leukemia / Neelam Verma and Kuldeep Kumar -- Breast cancer detection using surface plasmon resonance-based biosensors / Chii-Wann Lin and Chia-Chen Chang -- Detection of miRNA with silicon nanowire biosensors / Guo-Jun Zhang -- Biosensors for BCR-ABL activity and their application to cancer / Yusuke Ohba ... [et al.] -- Optical fiber nanobiosensor for single living cell detections of cancers / Xin Ting Zheng and Chang Ming Li -- Microfluidic biosensors for thyroglobulin detection and application to thyroid cancer / Seokheun Choi and Junseok Chae -- Optical biosensors and applications to drug discovery and development in cancer research / Carlo Bertucci and Angela De Simone -- Single-chain fragment variable recombinant antibodies and their applications in biosensors for cancer diagnosis / Xiangqun Zeng and Ray Mernaugh -- DNA biosensor for rapid detection of anticancer drugs / Sigen Wang and Ruili Wang -- Using UV light to engineer biosensors for cancer detection : the case of prostate specific antigen / Maria Teresa Neves-Petersen, Antonietta Parracino, and Steffen B. Petersen.
  • 2010 Springer
    edited by Ramkrishna Sen.
    Also available: Print – 2010
  • 2006 Springer
    [edited by] Maria Teresa Giardi, Elena V. Piletska.
    Introduction: the emergence of a new technology / Maria Teresa Giardi -- A brief story of biosensor technology / Marco Mascini -- Photosystem II: composition and structure / Aspasia Spyridaki, Emmanuel Psylinakis, and Demetrios F. Ghanotakis -- Biogenesis and structural dynamics of the photosystem II complex / Josef Komenda ... [et al.] -- Engineering the D1 subunit of photosystem II: application to biosensor technology / Udo Johanningmeier ... [et al.] -- Chloroplast genomics of land plants and algae / Margarita S. Odintsova and Nadezhda P. Yurina -- Comparison of the immobilization techniques for photosystem II / Regis Rouillon ... [et al.] -- Comparison of photosynthetic organisms of the evolution scale for protein biochips / Maria Teresa Giardi, Dania Esposito, and Giuseppe Torzillo -- Signal transduction techniques for photosynthetic proteins / Pinalysa Cosma, Francesco Longobardi, and Angela Agostiano -- Biotechnological and computational approaches for the development of biosensors / Giulio Testone ... [et al.] -- The problem of herbicide water monitoring in Europe / Licia Guzzella and Fiorenzo Pozzoni -- Application of chloroplast D1 protein in biosensors for monitoring photosystem II-inhibiting herbicides / Elena V. Piletska, Sergey A. Piletsky, and Regis Rouillon -- Photosystem II-based biosensors for the detection of photosynthetic herbicides / Maria Teresa Giardi and Emanuela Pace -- Mimicking the plastoquinone-binding pocket of photosystem II using molecularly imprinted polymers / Florent Breton ... [et al.] -- Photosystem II biosensors for heavy metals monitoring / Regis Rouillon ... [et al.] -- Development of biosensors for the detection of hydrogen peroxide / Louisa Giannoudi, Elena V. Piletska, and Sergey A. Piletsky -- Biodevices for space research / Dania Esposito ... [et al.] -- Successes in the development and application of innovative techniques / Eleftherios touloupakis ... [et al.].
  • 2013 Wiley
    Rodney J.Y. Ho, Milo Gibaldi.
    Introduction to biopharmaceuticals -- Distinctions of biologic versus small molecule platforms in drug development -- Financing biologic drug development -- Application of biotechnology in drug discovery and early development -- Large-scale production of recombinant proteins -- Clinical pharmacology, toxicology, and therapeutic dosage & response -- Clinical evaluation and regulatory approval & enforcement of biopharmaceuticals -- Pharmacoeconomics and drug pricing / Garrison -- Antibodies and derivatives -- Hematopoietic growth and coagulation factors -- Cytokines and interferons -- Hormones -- Enzymes -- Vaccines / Hu, Ho -- Other biopharmaceutical products -- Advances in personalized medicine : pharmacogenetics in drug therapy -- Gene and cell therapy -- Pharmacoeconomics, outcome, and health technology assessment research in drug development -- Summary and future prospects.
  • v. 27-, 2003- CRCnetBase
    v. 29, 2005 CRCnetBase
  • v. 4-, 2006- Springer
  • 2014 CRCnetBASE
    Firdos Alam Khan.
    "This book is a comprehensive overview of all the important aspects of medical biotechnology intended for interested, scientifically oriented laypersons, along, who want a relatively low level presentation of important biotechnology medical specialties such as bacteriology, immunology, recombinant DNA, molecular diagnostics, gene therapy, synthetic biology, tissue engineering, bioethics, IP issues, vaccines, and more"-- Provided by publisher.
  • 2011 Springer
    Alfonso Barbarisi (ed.) ; in collaboration with Paolo Bechi, Paolo Innocenti, Carlo Alberto Redi, Francesco Rosso ; foreword by Enrico De Antoni.
  • 2012 CRCnetBASE
    editor, V. K. Gupta ; co-editor, M. Ayyachamy.
    Identification of fungal pathogenicity genes by Agrobacterium tumefaciens-mediated transformation / Karunakaran Maruthachalam ... [et al.] -- The genetics and molecular biology of carotenoid biosynthesis in mucorales / Catalina Sanz, Mahdi Shahriari, and Arturo P. Eslava -- Induction and repression of carbohydrate degrading enzymes in fungi with special reference to their coding genes / Pauline Walsh, Alan Hernon, and Anthonia O'Donovan -- Involvement of ADH1, IPT1, and PMT genes in Candida albicans pathogenesis / Mahmoud Rouabhia and Mahmoud Ghannoum -- Enhanced resistance to fungal pathogens in plants through selective utilization of useful fungal genes / B.K. Sarma ... [et al.] -- Genes encoding penicillin and cephalosporin biosinthesis in Acremonium chrysogenum : two separate clusters are required for cephalosporin production / Juan-Francisco Martøn, Carlos Garcia-Estrada, and Ricardo V. Ullon -- A review of the fungal B-galactosidase gene and its biotechnological applications / Anne G. Lydon -- Trichoderma genes involved in interactions with fungi and plants / Mala Mukherjee -- Use of luciferases as a tool to analyze fungal physiology in association with gene transcription / David M. Arana and Jess Pla -- Fungal genes and their respective enzymes in industrial food, bio-based, and pharma applications / Marco van den Berg ... [et al.] -- Fungal metacaspases : an overview / Anthonia O'Donovan, Finola E. Cliffe, and Mary C. Shier -- Signaling molecules in the Arbuscular mycorrhizal fungi / Mohammad Miransari -- Role of pathogenic genes of Fusarium oxysporum, coding cell wall degrading enzymes during wilt infection in plants / Vijai Kumar Gupta, Maria Tuohy, and A. Manimaran -- Engineering fungal expression systems : recombinant expression of two class I alpha-1, 2-mannosidases from the filamentous fungus Aspergillus nidulans / C. Joshua Eades and William E. Hintz -- PCR-diagnostic of Septoria nodorum berk : aggresivenes in wheat tissue / I.V. Maksimov and A.Sh. Valeev -- Detection of toxigeneic and pathogenic fungi targeting metabolic pathway genes / Venkataramana Mudili ... [et al.] -- Pathogenicity genes in entomopathogenic fungia used as biopesticides / K. Uma Devi ... [et al.].
  • 2013 CRCnetBASE
    Roger L. Lundblad.
    "Discussing the role of plasma proteins in current biotechnology, this book describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, and mass spectrometry as well as updates not published since 1975"--Provided by publisher.
  • 2006 Springer
    Sydney Lou Bonnick, Lori Ann Lewis.
  • 2013 Springer
    Sydney Lou Bonnick, Lori Ann Lewis.
    An introduction to conventions in densitometry -- Densitometry techniques -- Skeletal anatomy in densitometry -- Performing a DXA PA lumbar spine, proximal femur, or forearm DXA study -- Radiation safety in x-ray densitometry -- Quality control procedures -- The importance of precision -- Using absolute risk to predict fracture risk in clinical practice -- An overview of osteoporosis -- Interpretation of bone densitometry data -- Less than perfect scan images -- Pediatric densitometry -- VFA imaging, femoral morphometry, and hip structural analysis -- Body composition analysis.
  • 2013 ebrary
    James T. Bradley.
    A guide to the rapidly progressing Age of Biotechnology, Brutes or Angels provides basic information on a wide array of new technologies in the life sciences, along with the ethical issues raised by each. With stem cell research, Dolly the cloned sheep, in vitro fertilization, age retardation, and pharmaceutical mind enhancement, humankind is now faced with decisions that it has never before had to consider. The thoughtfulness, or lack of it, that we bring to those decisions will largely determine the future character of the living world.
  • 2005 NCBI Bookshelf
    Eric Sayers and David Wheeler.
  • 2008 ebrary
    Martin Austin.
    The role of business development -- Planning the portfolio -- Identifying the needs -- Profiling and searching for opportunities -- Modelling and valuation -- Structuring for value -- Due diligence and negotiations -- Sealing the deal : the control -- Making the transaction work.
  • 2010 ScienceDirect
    Frank H. Stephenson.
    Chapter 1. Scientific notation and metric prefixes -- Chapter 2. Solutions, mixtures, and media -- Chapter 3. Cell growth -- Chapter 4. Working with bacteriophages -- Chapter 5. Nucleic acid quantification -- Chapter 6. Labeling nucleic acids with radioisotopes -- Chapter 7. Oligonucleotide synthesis -- Chapter 8. The polymerase chain reaction (PCR) -- Chapter 9. The real-time polymerase chain reaction (RT-PCR) -- Chapter 10. Recombinant DNA -- Chapter 11. Protein -- Chapter 12. Centrifugation -- Chapter 13. Forensics and paternity.
  • 2014 Springer Protocols
    edited by Milica Radisic, Lauren D. Black III.
    Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts / Sebastian Diecke ... [and 3 others] -- Scalable cardiac differentiation of human pluripotent stem cells as microwell-generated, size controlled three-dimensional aggregates / Celine L. Bauwens and Mark D. Ungrin -- Preparation and characterization of circulating angiogenic cells for tissue engineering applications / Aleksandra Ostojic ... [and 4 others] -- Isolation and expansion of C-kit-positive cardiac progenitor cells by magnetic cell sorting / Kristin M. French and Michael E. Davis -- Synthesis of aliphatic polyester hydrogel for cardiac tissue engineering / Sanjiv Dhingra, Richard D. Weisel, and Ren-Ke Li -- Fabrication of PEGylated fibrinogen : a versatile injectable hydrogel biomaterial / Iris Mironi-Harpaz, Alexandra Berdichevski, and Dror Seliktar -- Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes / Donald O. Freytes ... [and 4 others] -- Magnetically actuated alginate scaffold : a novel platform for promoting tissue organization and vascularization / Yulia Sapir ... [and 3 others.] -- Shrink-induced biomimetic wrinkled substrates for functional cardiac cell alignment and culture / Nicole Mendoza ... [and 4 others] -- Injectable ECM scaffolds for cardiac repair / Todd D. Johnson, Rebecca L. Braden, and Karen L. Christman -- Generation of strip-format fibrin-based engineered heart tissue (EHT) / Sebastian Schaaf ... [and 5 others.] -- Cell tri-culture for cardiac vascularization / Ayelet Lesman, Lior Gepstein, and Shulamit Levenberg -- Cell sheet technology for cardiac tissue engineering / Yuji Haraguchi ... [and 8 others] -- Design and fabrication of biological wires / Jason W. Miklas ... [and 3 others] -- Collagen-based engineered heart muscle / Malte Tiburcy ... [and 3 others] -- Creation of a bioreactor for the application of variable amplitude mechanical stimulation of fibrin gel-based engineered cardiac tissue / Kathy Y. Morgan and Lauren D. Black III -- Preparation of acellular myocardial scaffolds with well- preserved cardiomyocyte lacunae, and method for applying mechanical and electrical simulation to tissue construct / Bo Wang ... [and 3 others] -- Patch-clamp technique in ESC-derived cardiomyocytes / Jie Liu and Peter H. Backx -- Optogenetic control of cardiomyocytes via viral delivery / Christina M. Ambrosi and Emilia Entcheva -- Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts / Wei-Zhong Zhu ... [and 3 others] -- Quantifying electrical interactions between cardiomyocytes and other cells in micropatterned cell pairs / Hung Nguyen ... [and 4 others].
  • 2008 Springer
    2008 ebrary
    edited by Guruprasad Madhavan, Barbara Oakley, Luis Kun ; editorial by Joachim Nagel ; foreword by Robert Langer ; introduction by Bruce Alberts ; afterword by Shu Chien.
    What makes a bioengineer and a biotechnologist? / Robert A. Linsenmeier, David W. Gatchell -- Bioengineering and biotechnology: a European perspective / Joachim H. Nagel -- Bioengineering and biotechnology: an Asia-Pacific perspective / Makoto Kikuchi, James C.H. Goh -- Employment outlook and motivation for career preparation / John D. Enderle -- Academic research and teaching / Nitish V. Thakor -- Teaching colleges and universities / Maria E. Squire -- Industry research and management / Mark W. Kroll -- Independent research laboratories / David J. Schlyer -- Public sector research, development, and regulation / Jove Graham -- Clinical medicine and healthcare / Leann M. Lesperance -- Intellectual property law / Kenneth H. Sonnenfeld -- Clinical engineering / Jennifer McGill -- Entrepreneurship in medical device technologies / Dany Bérubé -- Entrepreneurship in pharmaceutical and biological drug discovery and development / Robert G.L. Shorr -- Human implantable technologies / Joseph H. Schulman -- Specialized careers in healthcare / Charles H. Kachmarik, Jr. -- Finance and investment industry / Kristi A. Tange -- Regulatory affairs / Ronald A. Guido, Alan V. McEmber -- Clinical research careers / Kathi G. Durdon -- Science and technology policy / Luis G. Kun -- Forensic psychology / Diana M. Falkenbach -- Energy / Mary E. Reidy -- Technology transfer / Eugene B. Krentsel -- Politics and legislation / David R. Koon -- Social entrepreneurship / Robert A. Malkin -- Technology and management consulting / Guruprasad Madhavan -- Expert witness and litigation consulting / John G. Webster -- Public relations / Cynthia Isaac -- Sales and marketing / Jason M. Alter -- Sports engineering / Celeste Baine -- Writing non-fiction books / Barbara A. Oakley -- Emerging innovative careers / Guruprasad Madhavan, Jennifer A. Flexman, Aimee L. Betker -- Holistic engineering: the dawn of a new era for the profession / Domenico Grasso, David Martinelli -- On searching for new genes: a 21st century DNA for higher education and lifelong learning / Rick L. Smyre -- Protean professionalism and career development / Steven Kerno, Jr. -- Leadership through social artistry / Jean Houston -- Career and life management skills for success / Bala S. Prasanna -- Perspectives on ethical development: reflections from life and profession / Jerry C. Collins -- Technology development and citizen engagement / Joseph O. Malo -- In defense of science and technology / Elizabeth M. Whelan -- Science, ethics, and human destiny / John c. Polanyi -- Motives, ethics, and responsibility in research and technology development / Subrata Saha, Pamela Saha -- Science and technology policy for social development / Semahat S. Demir -- Medicine and health safety / Richard A. Baird, Roderic I. Pettigrew -- Patient safety: building a triangle of importance / T.K. Partha Sarathy -- Design of appropriate medical technologies: engineering social responsibility and awareness / Nigel H. Lovell -- Ubiquitous healthcare: a fundamental right in the civilized world / Pradeep Ray, Dhanjoo Ghista -- Towards affordable and accessible healthcare systems / Xiaofei F. Teng, Yuan-Ting Zhang -- From war to law via science / John C. Polanyi -- Science and technology for sustainable well-being / Rajendra K. Pachauri -- Nonviolence for technocrats / Arun M. Gandhi -- Humanistic science and technology for a hunger-free world / M.S. Swaminathan -- Feeding the hungry / Norman E. Borlaug -- Environmental consciousness and sustainable engineering design / Raghav Narayanan, Ashbindu Singh -- Improving public health quality and equity through effective use of technology / Andrei Issakov, S. Yunkap Kwankam -- Information sharing in the 21st century / Vinton G. Cerf -- Energy and sustainability in the 21st century / John P. Holdren -- Health and human rights: a global mandate / Sarah Hall Gueldner -- Gender equality: progress and challenges / Yunfeng Wu, Yachao Zhou, Metin Akay -- Complexity: mastering the interdependence of biology, engineering and health / Yaneer Bar-Yam -- Enhancing humanity / Raymond C. Tallis -- Translational research / Gail D. Baura -- Research paving the way for therapeutics and diagnostics / Dieter Falkenhagen -- Interdisciplinary collaboration and competency development / Joaquin Azpiroz Leehan -- The 21st century mind: the roles of a futures institute / Rick L. Smyre -- Accelerating innovation in the 21st century / Ralph W. Wyndrum, Jr. -- Benign application of knowledge through evolutionary theory / David Sloan Wilson -- Honor thy profession / Max E. Valentinuzzi -- Technical leadership: an international imperative / Barry L. Shoop -- The art of achieving the menschhood / Guy Kawasaki -- Ten questions for individual leadership development / John C. Maxwell.
  • 2008
    Toby Freedman.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer Protocols
    edited by Pauline M. Doran.
    Cartilage tissue engineering : what have we learned in practice / Pauline M. Doran -- Human fetal and adult chondrocytes / Kifah Shahin, Nastaran Mahmoudifar, and Pauline M. Doran -- Mesenchymal stem cells derived from human bone marrow / Oliver F. W. Gardner, Mauro Alini, and Martin J. Stoddart -- Mesenchymal stem cells derived from human adipose tissue / Nastaran Mahmoudifar and Pauline M. Doran -- Derivation and chondrogenic commitment of human embryonic stem cell-derived mesenchymal progenitors / Hicham Drissi ... [et al.] -- Differentiation of human induced pluripotent stem cells to chondrocytes / Rosa M. Guzzo and Hicham Drissi -- Gene transfer and gene silencing in stem cells to promote chondrogenesis / Feng Zhang and Dong-An Wang -- Hydrogels with tunable properties / Peggy P.Y. Chan -- Decellularized extracellular matrix scaffolds for cartilage regeneration / Shraddha Thakkar, Hugo Fernandes, and Lorenzo Moroni -- Use of interim scaffolding and neotissue development to produce a scaffold-free living hyaline cartilage graft / Ting Ting Lau ... [et al.] -- Bioprinted scaffolds for cartilage tissue engineering / Hyun-Wook Kang, James J. Yoo, and Anthony Atala -- Scaffolds for controlled release of cartilage growth factors / Marie Morille ... [et al.] -- Nanostructured capsules for cartilage tissue engineering / Clara R. Correia, Rui L. Reis, and João F. Mano -- Stratified scaffolds for osteochondral tissue engineering / Patcharakamon Nooeaid, Gundula Schulze-Tanzil, and Aldo R. Boccaccini -- Mechanobioreactors for cartilage tissue engineering / Joanna F. Weber, Roman Perez, and Stephen D. Waldman -- Shear and compression bioreactor for cartilage synthesis / Kifah Shahin and Pauline M. Doran -- Microbioreactors for cartilage tissue engineering / Yu-Han Chang and Min-Hsien Wu -- Transplantation of tissue-engineered cartilage in an animal model (xenograft and autograft) : construct validation / Hitoshi Nemoto, Deborah Watson, and Koichi Masuda -- Proteomic analysis of engineered cartilage / Xinzhu Pu and Julia Thom Oxford -- Mechanical testing of cartilage constructs / Dinorath Olvera, Andrew Daly, and Daniel John Kelly.
  • 2005 CRCnetBASE
    edited by Sadettin S. Ozturk, Wei-Shou Hu.
  • 2009 Springer
    Adrian Gee, editor.
    Part 1. Regulatory. -- Regulation of Cell Product Manufacturing and Delivery: A United States Perspective / R.W. Lindblad -- The Regulatory Situation for Academic Cell Therapy Facilities in Europe / I. Slaper-Cortenbach, M. Scott, D. Herrmann, M. Introna and K. Theunissen, et al. -- A Regulatory System for Cell and Tissue Therapies: Proposed Approach in Australia / A. Farrugia -- Part 2. GMP Facility Design. -- University of Minnesota - Molecular and Cellular Therapeutics (MCT) / D.H. McKenna -- University of Pittsburgh Cancer Institute - Hematopoietic Stem Cell Laboratory (HSC Lab)/Immunological Monitoring and Cellular Products Laboratory (IMCPL) / D.L. Griffin, A.D. Donnenberg and T.L. Whiteside / Baylor College of Medicine - Center for Cell and Gene Therapy (CAGT) / A. Gee -- Design of a New GMP Facility - Lessons Learned / A. Gee -- Part 3. Professional Cell Therapy Standards. -- AABB Cell Therapy Standards / Z.M. Szczepiorkowski and E. Nunes -- Professional Standards for Cellular Therapies: Foundation for the Accreditation of Cellular Therapy (FACT) / P.I. Warkentin -- Part 4. Facility Operations -- Standard Operating Procedures / C.G. Lindgren -- Staffing, Training, and Competency / D.M. Kadidlo -- Cleaning Procedures / A. Gee and D.L. Lyon -- Environmental Monitoring / A. Gee and D.L. Lyon -- Supply Management / A. Gee and C.M. Rooney -- Facility Equipment / D.L. Griffin -- Quality / J.W. Atkins -- Product Manufacturing / A. Gee -- Product Review, Release, and Administration / N.H. Collins -- Use of a Facility Master File to Facilitate Regulatory Submissions for Cell Therapy Products / E.J. Read and H.M. Khuu.
  • 2013 Springer Protocols
    edited by Volkmar Weissig, Tamer Elbayoumi, and Mark Olsen.
    Nanoparticle-GFP "chemical nose" sensor for cancer cell identification / Daniel F. Moyano and Vincent M. Rotello -- Method to map spatiotemporal pH changes in a multicellular living organism using a DNA nanosensor / Sunaina Surana and Yamuna Krishnan -- Simple method to visualize and assess the integrity of lysosomal membrane in mammalian cells using a fluorescent dye / Syed K. Sohaebuddin and Liping Tang -- Gold nanoparticle as a marker for precise localization of nano-objects within intracellular sub-domains / Valeriy Lukyanenko and Vadim Salnikov -- Immunoisolation of nanoparticles containing endocytic vesicles for drug quantitation / Ari Nowacek [and others] -- Methods for isolation and identification of nanoparticle-containing subcellular compartments / Ari Nowacek [and others] -- Permeabilization of cell membrane for delivery of nano-objects to cellular sub-domains / Valeriy Lukyanenko -- Method to encapsulate molecular cargo within DNA Icosahedra / Dhiraj Bhatia [and others] -- Delivery of plasmid DNA to mammalian cells using polymer-gold nanorod assemblies / James Ramos, Huang-Chiao Huang, and Kaushal Rege -- Lipophilic-formulated gold porphyrin nanoparticles for chemotherapy / Puiyan Lee and Kenneth K.Y. Wong -- Mitochondria-specific nano-emulsified therapy for myocardial protection against doxorubicin-induced cardiotoxicity / Amy Faulk, Volkmar Weissig, and Tamer Elbayoumi -- Formation of pit-spanning phospholipid bilayers on nanostructured silicon dioxide surfaces for studying biological membrane events / Indriati Pfeiffer and Michael Zach -- Characterization of nanoparticle-lipid membrane interactions using QCM-D / Rickard Frost and Sofia Svedhem -- Single-cell nanosurgery / Maxwell B. Zeigler and Daniel T. Chiu -- Single quantum dot imaging in living cells / Jerry C. Chang and Sandra J. Rosenthal -- Fabrication of fluorescent silica nanoparticles with aggregation-induced emission luminogens for cell imaging / Sijie Chen, Jacky W.Y. Lam, and Ben Zhong Tang -- Monitoring the degradation of reduction-sensitive gene carriers with fluorescence spectroscopy and flow cytometry / Constantin Hozsa, Miriam Breunig, and Achim Gopferich -- Quantification of intracellular mitochondrial displacements in response to nanomechanical forces displacements in response to nanomechanical forces / Yaron R. Silberberg and Andrew E. Pelling -- Imaging select mammalian organelles using fluorescent microscopy : application to drug delivery / Paul D.R. Dyer [and others] -- Real-time particle tracking for studying intracellular trafficking of pharmaceutical nanocarriers / Feiran Huang [and others] -- Interactions of nanoparticles with proteins : determination of equilibrium constants / Lennart Treuel and Marcelina Malissek -- Tracing the endocytic pathways and trafficking kinetics of cell signaling receptors using single QD nanoparticles / Katye M. Fichter and Tania Q. Vu -- Cellular internalization of quantum dots / Yue-Wern Huang [and others] -- Electrochemical scanning tunneling microscopy and spectroscopy for single-molecule investigation / Andrea Alessandrini and Paolo Facci -- Intracellular delivery of biologically active proteins with peptide-based carriers / Seong Loong Lo and Shu Wang -- Lipo-oligoarginine-based intracellular delivery / Jae Sam Lee and Ching-Hsuan Tung -- Fluorescent spherical monodisperse silica core-shell nanoparticles with a protein-binding biofunctional shell / Achim Weber, Marion Herz, and Gunter E.M. Tovar -- Direct quantification of PTD transduction using real-time monitoring / Mi-Sook Lee and Song Her -- Genotoxic assessment of carbon nanotubes / Olivera Neskovic [and others] -- Separation science : principles and applications for the analysis of bionanoparticles by asymmetrical flow field-flow fractionation (AF4) / Alexandre Moquin, Francoise M. Winnik, and Dusica Maysinger -- Polymersomes-mediated delivery of fluorescent probes for targeted and long-term imaging in live cell microscopy / Irene Canton and Giuseppe Battaglia -- Protocol for the preparation of stimuli-responsive gold nanoparticles capped with elastin-based pentapeptides / Vincent Lemieux, P. Hans H.M. Adams, and Jan C.M. van Hest.
  • 2012 ScienceDirect
    edited by Harry J. Gilbert.
    Cellulase refers to a class of enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis. This volume in the Methods in Enzymology series comprehensively covers this topic.
  • 2015 Springer Protocols
    edited by Jonathan E. Hempel, Charles H. Williams, Charles C. Hong.
    Identification of Therapeutic Small Molecule Leads in Cultured Cells Using Multiplexed Pathway Reporter Read-outs -- Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles -- Construction and Application of a Photo-cross-linked Chemical Array -- High Content Screening for Modulators of Cardiac Differentiation in Human Pluripotent Stem Cells -- Small Molecule High-Throughput Screening Utilizing Xenopus Egg Extract -- Fission Yeast-based High-throughput Screens for PKA Pathway Inhibitors and Activators -- A Method for High-throughput Analysis of Chronological Aging in Schizosaccharomyces pombe -- Protocols for the Routine Screening of Drug Sensitivity in the Human Parasite Trichomonas vaginalis -- Chemical Genetic Screens Using Arabidopsis thaliana Seedlings Grown on Solid Medium -- Small Molecule Screening Using Drosophila Models of Human Neurological Disorders -- High-throughput Small Molecule Screening in Caenorhabditis elegans -- Whole-organism Screening for Modulators of Fasting Metabolism Using Transgenic Zebrafish -- High Content Screening for Modulators of Cardiovascular or Global Developmental Pathways in Zebrafish -- Extraction Methods of Natural Products from Traditional Chinese Medicines -- Bioassay-guided Identification of Bioactive Molecules from Traditional Chinese Medicines -- NMR Screening in Fragment-Based Drug Design: A Practical Guide -- Practical Strategies for Small Molecule Probe Development in Chemical Biology -- Principal Component Analysis as a Tool for Library Design: A Case Study Investigating Natural Products, Brand-name Drugs, Natural Product-like Libraries, and Drug-like Libraries -- Small Molecule Library Screening by Docking with PyRx -- Fluorous Photoaffinity Labeling to Probe Protein-Small Molecule Interactions -- Identification of the Targets of Biologically Active Small Molecules Using Quantitative Proteomics -- Drug Affinity Responsive Target Stability (DARTS) for Small Molecule Target Identification -- Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action -- Image-Based Prediction of Drug Target in Yeast.
  • v. 1-2, 2004 Wiley
    C.N.R. Rao, A. Müller, A.K. Cheetham (eds.).
    v. 1. Nanomaterials : an introduction / C.N.R. Rao, A. Müller, A.K. Cheetham -- Strategies for the scalable synthesis of quantum dots and related nanodimensional materials / Paul O'Brien, N. Pickett -- Moving nanoparticles around : phase-transfer processes in nanomaterials synthesis / M. Sastry -- Mesoscopic assembly and other properties of metal and semiconductor nanocrystals / G.U. Kulkarni, P.J. Thomas, C.N.R. Rao -- Oxide nanoparticles / R. Seshadri -- Sonochemistry and other novel methods developed for the synthesis of nanoparticles / Y. Mastai, A. Gedanken -- Solvothermal synthesis of non-oxide nanomaterials / Y.T. Qian, Y.L. Gu, J. Lu -- Nanotubes and nanowires / A. Govindaraj, C.N.R. Rao -- Synthesis, assembly and reactivity of metallic nanorods / C.J. Murphy ... [et al.] -- Oxide-assisted growth of silicon and related nanowires : growth mechanism, structure and properties / S.T. Lee, R.Q. Zhang, Y. Lifshitz -- v. 2. Electronic structure and spectroscopy of semiconductor nanocrystals / S. Sapra, D.D. Sarma -- Core-shell semiconductor nanocrystals for biological labeling / R.E. Bailey, S. Nie -- Large semiconductor molecules / J.F. Corrigan, M.W. DeGroot -- Oxomolybdates : from structures to functions in a new era of nanochemistry / A. Müller, S. Roy -- Nanostructured polymers / S. Ramakrishnan -- Recent developments in the chemistry and chemical applications of porous silicon / J.M. Schmeltzer, J.M. Buriak -- Nanocatalysis / S. Abbet, U. Heiz -- Nanoporous materials / A.K. Cheetham, P.M. Forster -- Photochemistry and electrochemistry of nanoassemblies / P.V. Kamat -- Electrochemistry with nanoparticles / S. Devarajan, S. Sampath -- Nanolithography and nanomanipulation / A.K. Raychaudhuri.
  • 2014 Springer Protocols
    edited by Pal Maliga.
    The Plastid Genomes of Flowering Plants -- Next Generation Technologies to Determine Plastid Genome Sequences -- Plastid Gene Transcription: Promoters and RNA Polymerases -- Plastid mRNA Translation -- Engineering Chloroplasts for High-Level Foreign Protein Expression -- Excision of Plastid Marker Genes Using Directly Repeated DNA Sequences -- Fluorescent Labeling and Confocal Microscopic Imaging of Chloroplasts and Non-Green Plastids -- Plastid Transformation in Nicotiana tabacum and Nicotiana sylvestris by Biolistic DNA Delivery to Leaves -- Nicotiana tabacum PEG-mediated Plastid Transformation -- Plastid Transformation of Tobacco Suspension Cell Cultures -- Tryptophan and Indole Analog Mediated Plastid Transformation -- Plastid Marker Gene Excision in Greenhouse-Grown Tobacco by Agrobacterium-Delivered Cre Recombinase -- Determination of the Half-Life of Chloroplast Transcripts in Tobacco Leaves -- Quantification of Organellar DNA and RNA Using Real-Time PCR -- Plastid Transformation for Rubisco Engineering and Protocols for Assessing Expression -- Plastid Transformation in Tomato -- Stable Plastid Transformation of Petunia -- Plastid Transformation in Potato -- Solanum tuberosum -- Plastid Transformation in Eggplant -- Plastid Transformation in Lettuce (Lactuca sativa L.) by Polyethylene Glycol Treatment of Protoplasts -- Plastid Transformation in Lettuce (Lactuca sativa L) by Biolistic DNA Delivery -- Plastid Transformation in Soybean -- Plastid Transformation in Cabbage (Brassica oleracea L. var. capitata L.) by the Biolistic Process -- Plastid Transformation in Sugar Beet Beta vulgaris -- Integration and Expression of gfp in the Plastid of Medicago sativa L. -- Rapid Screening for the Robust Expression of Recombinant Proteins in Algal Plastids -- A Simple, Low Cost Method for Chloroplast Transformation of the Green Alga Chlamydomonas reinhardtii -- Tools for Regulated Gene Expression in the Chloroplast of Chlamydomonas -- Plastid Transformation in Physcomitrella patens -- Plastid Transformation of Sporelings and Suspension-cultured Cells from the Liverwort Marchantia polymorpha L.
  • 2005 Springer
    George P. Smith, II.
  • 2008 CRCnetBASE
    edited by Kiichi Fukui, Tatsuo Ushiki.
    Mechanical approaches to elucidate mechanisms of chromosome condensation at the nano- and microlevels / Kazushige Kawabata ... [et al.] -- Development of novel AFM probes for chromosome manipulation / Masato Saito, Gen Hashiguchi and Eiichi Tamiya -- Microchamber array-based sequence-specific DNA detection from a single chromosome via trace volume PCR / Masato Saito and Eiichi Tamiya -- On-chip chromosome sorter using electric and magnetic fields / Takahito Inoue ... [et al.] -- Fluorescence microscopy for analysis of chromosome dynamics / Sachihiro Matsunaga -- Fluorescence in situ hybridization (FISH) as a tool for comparative genomics: application of FISH to studies of chromosome evolution in vertebrates / Yoichi Matsuda ... [et al.] -- Immunocytochemistry for analyzing chromosomes / Osamu Hoshi ... [et al.] -- Proteome analysis of human metaphase chromosomes / Kiichi Fukui and Susumu Uchiyama -- Antipeptide antibodies for examining the conformation and molecular assembly of an intracellular protein / Masatoshi Nakagawa ... [et al.] -- Structure and interactions of the imitation SWI-type chromatin-remodeling complex, ATP-dependent chromatin-assembly facter / Tadayasu Ohkubo ... [et al.] -- Dynamic and functional analysis of chromosomal proteins / Nobuko Ohmido ... [et al.] -- Development of a sustainable chromosome imaging database / Kenji Taniguchi ... [et al.] -- Image database and image analysis of chromosome information / Shin-ichi Toyabe ... [et al.]. Transmission and scanning electron microscopy of mammalian metaphase chromosomes / Sumire Inaga, Keiichi Tanaka and Tatsuo Ushiki -- Atomic force microscopy of human chromosomes in relation to their higher-order structure / Osamu Hoshi, Daisuke Fukushi and Tatsuo Ushiki -- Mechanism of higher-order chromatin folding revealed by AFM observation of in vitro reconstituted chromatin / Kohji Hizume ... [et al.] -- Scanning near-field optical/atomic force microscopy as a tool for simultaneous specification of chromosome topography and particular gene location on the nanometer scale / Motoharu Shichiri ... [et al.] -- Isolation of human and plant chromosomes as nanomaterials / Susumu Uchiyama, Tomoyuki Doi and Kiichi Fukui --
  • 2011 Springer
    Stephen Kee, Julie Gehl, Edward W. Lee, editors.
    Introduction to Electroporation -- Electroporation and Cellular Physiology -- The Cell in the Electric Field -- Understanding Electric Fields for Clinical Use -- Generators and Applicators: Equipment for Electroporation -- Cell Electropermeabilization and Cellular Uptake of Small Molecules: The Electrochemotherapy Concept -- Vascular-Disrupting Action of Electrochemotherapy: Mode of Action and Therapeutic Implications -- Electrochemotherapy of Small Tumors; The Experience from the ESOPE (European Standard Operating Procedures for Electrochemotherapy) Group -- Electrochemotherapy for Larger Malignant Tumors -- Cell Electroporation in Bone Tissue -- Drug and Gene Electrotransfer to the Brain -- Minimally Invasive Intraluminal Tumor Ablation -- Electrotransfer of Plasmid DNA -- Gene Electrotransfer to Tumor -- Gene Electrotransfer to Lung -- Gene Electrotransfer to Muscle Tissue: Moving into Clinical Use -- Gene Electrotransfer to Skin -- Electroporation-Mediated DNA Vaccination -- Irreversible Electroporation (IRE) on Liver Tumor Ablation: A Summary of Preclinical Translational Research -- Translational Research on Irreversible Electroporation: VX2 Rabbit Head and Neck -- Clinical Research on Irreversible Electroporation of the Liver.
  • 2013 Springer
    Elisabeth Hildt, Andreas G. Franke, editors.
    Medical and Psychosocial Aspects of Cognitive Enhancement -- Pharmacological Neuroenhancement: Substances and Epidemiology / Andreas G. Franke, Klaus Lieb -- Psychopharmacological Neuroenhancement: Evidence on Safety and Efficacy / Dimitris Repantis -- A Bubble of Enthusiasm: How Prevalent Is the Use of Prescription Stimulants for Cognitive Enhancement? / Bradley Partridge -- Modeling the Effects of Modafinil on Selective Attention Electroencephalographic Neural Correlates / Carlos Trenado -- Behavioral Neuroenhancement / Martin Dresler -- The Influence of Sports on Cognitive Task Performance - A Critical Overview / Pavel Dietz -- The Human Experiment: How We Won't Win the Rat Race. What Can We Learn from Brain Stimulation in Humans and Rats About Enhancing the Functional Neurobiology of Higher Cognitive Functions? / Colleen A. Dockery -- Philosophical and Ethical Aspects of Cognitive Enhancement -- Better Brains or Bitter Brains? The Ethics of Neuroenhancement / Kirsten Brukamp -- Cognitive Enhancement - To What End? / Michael Hauskeller -- Nano-bionic Devices for the Purpose of Cognitive Enhancement: Toward a Preliminary Ethical Framework / Frédéric Gilbert -- Cognitive-Enhancing Drugs, Behavioral Training and the Mechanism of Cognitive Enhancement / Emma Peng Chien -- What Is Cognitive Enhancement and Is It Justified to Point Out This Kind of Enhancement Within the Ethical Discussion? / Roland Kipke -- No Pain, No Gain? Objections to the Use of Cognitive Enhancement on the Basis of Its Potential Effects on the Value of Achievement / Lisa Forsberg -- Does the Cognitive Enhancement Debate Call for a Renewal of the Deliberative Role of Bioethics? / Cynthia Forlini, Eric Racine -- Sociological, Political and Legal Aspects of Cognitive Enhancement -- The Biopolitics of Cognitive Enhancement / Peter B. Reiner -- Are We Heading Towards an 'Enhancement Society'? / Armin Grunwald -- Leveling the Playing Field: Fairness in the Cognitive Enhancement Debate / Greta Wagner -- My Mind Is Mine!? Cognitive Liberty as a Legal Concept / Jan-Christoph Bublitz -- Cognitive Enhancement and Criminal Behavior / Elizabeth Shaw -- Enhanced Control and Criminal Responsibility / John Danaher.
  • 2014 ScienceDirect
    edited by Zhongmin Jin.
    1. Fundamentals of computational modelling of biomechanics in the musculoskeletal system -- 2. Finite element modeling in the musculoskeletal system: generic overview -- 3. Joint wear simulation -- 4. Computational modeling of cell mechanics -- 5. Computational modeling of soft tissues and ligaments -- 6. Computatonal modeling of muscle biomechanics -- 7. Computational modelling of articular cartilage -- 8. Computational modeling of bone and bone remodeling -- 9. Modelling fracture processes in bones -- 10. Modelling fatigue of bone cement -- 11. Modelling fracture processes in orthopaedic implants -- 12. Modelling cementless cup fixation in total hip arthroplasty (THA) -- 13. Computational modeling of hip implants -- 14. Computational modelling of knee implants -- 15. Computational modelling of spinal implants -- 16. Finite element modelling of bone tissue scaffolds -- Index.
  • 2012 Springer
    M. V. K. Karthik, Pratyoosh Shukla.
  • 2013 Springer
    Rolf Haaker, Werner Konermann (editors).
    Computer-assisted surgery is a growing sub-discipline of orthopaedic surgery. This book offers a comprehensive presentation of scientific work and clinical experience including new technologies like individual templating in unicompartmental and total knee arthoplasty based on computer-assisted design technology. Computer-assisted surgery involves not only total knee and total hip arthroplasty, but also trauma, sports and revision surgery. In this edition we have added sections on 3D fluoroscopy-based spinal surgery as well as 3D fluoroscopy-based trauma surgery. Even in total hip surgery, navigation systems offer exciting new aspects, and the clinical benefit of navigation in total knee arthroplasties has now been demonstrated. We believe that this textbook will be of interest to those new to this specific field, while also providing an update for experienced users. An added benefit is the international character of this textbook, including experiences from Switzerland, Israel, the United States and the German-speaking countries.
  • 2012 Springer Protocols
    edited by Michael A.K. Liebschner.
    Computer-aided tissue engineering : benefiting from the control over scaffold micro-architecture / Ahmad M. Tarawneh, Matthew Wettergreen, and Michael A.K. Liebschner -- Computer-aided approach for customized cell-based defect reconstruction / Ulrich Meyer, Jorg Neunzehn, and Hans Peter Wiesmann -- Novel bone scaffold design approach based on shape function and all-hexahedral mesh refinement / Shengyong Cai, Juntong Xi, and Chee Kai Chua -- Rapid prototyping composite and complex scaffolds with PAM2 / Giovanni Vozzi, Annalisa Tirella, and Arti Ahluwalia -- Scaffold pore space modulation through intelligent design of dissolvable microparticles / Michael A.K. Liebschner and Matthew Wettergreen -- Scaffold informatics and biomimetic design : three-dimensional medical reconstruction / Jorge Vicente Lopes da Silva, Tatiana Al-Chueyr Pereira Martins, and Pedro Yoshito Noritomi -- Development of computer-aided system for tissue scaffolds (CASTS) system for functionally graded tissue-engineering scaffolds / Novella Sudarmadji, Chee Kai Chua, and Kah Fai Leong -- Computer-designed nano-fibrous scaffolds / Laura A. Smith and Peter X. Ma -- Neural network technique for remeshing of bone microstructure / Anath Fischer and Yaron Holdstein -- Using the Taguchi method to obtain more finesse to the biodegradable fibers / Ville Ellssa [and others] -- Numerical modeling in the design and evaluation of scaffolds for orthopaedics applications / Wojciech Swieszkowski and Krzysztof J. Kurzydlowski -- Structural and vascular analysis of tissue engineering scaffolds, part 1 : numerical fluid analysis / Henrique A. Almeida and Paulo J. Bartolo -- Structural and vascular analysis of tissue engineering scaffolds, part 2 : topology optimisation / Henrique A. Almeida and Paulo J. Bartolo -- Modeling of bioreactor hydrodynamic environment and its effects on tissue growth / Bahar Bilgen and Gilda A. Barabino -- Recent advances in 3D printing of tissue engineering scaffolds / Min Lee and Benjamin M. Wu -- Graft-artery junctions : design optimization and CAD development / Yos S. Morsi [and others] -- Projection printing of 3-dimensional tissue scaffolds / Yi Lu and Shaochen Chen -- Laser sintering for the fabrication of tissue engineering scaffolds / Stefan Lohfeld and Peter E. McHugh -- Three-dimensional microfabrication by two-photon polymerization technique / Aleksandr Ovsianikov and Boris N. Chichkov -- Direct fabrication as a patient-targeted therapeutic in a clinical environment / Dietmar W. Hutmacher [and others] -- Microstereolithography-based computer-aided manufacturing for tissue engineering / Dong-Woo Cho and Hyun-Wook Kang.
  • 2011 Springer
    Shayne C. Gad, Charles B. Spainhour.
  • 2013 Springer
    Hideaki Yukawa, Masayuki Inui, editors.
    Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its "microbial factory" qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
  • 2014 Springer
    G. Cliff Lamb, Nicolas DiLorenzo, editors.
    This book addresses the impacts of current and future reproductive technologies on our world food production and provides a significant contribution to the importance of research in the area of reproductive physiology that has never been compiled before. It would provide a unique opportunity to separate the impacts of how reproductive technologies have affected different species and their contributions to food production. Lastly, no publication has been compiled that demonstrates the relationship between developments in reproductive management tools and food production that may be used a reference for scientists in addressing future research areas. During the past 50 years assisted reproductive technologies have been developed and refined to increase the number and quality of offspring from genetically superior farm animal livestock species. Artificial insemination (AI), estrous synchronization and fixed-time AI, semen and embryo cryopreservation, multiple ovulation and embryo transfer (MOET), in vitro fertilization, sex determination of sperm or embryos, and nuclear transfer are technologies that are used to enhance the production efficiency of livestock species.
    Also available: Print – 2014
  • 2010- Wiley
    editorial board, Adam Arkin ... [et al.].
    Current Protocols in Chemical Biology provides validated protocols and overviews about specialized chemical techniques and tools for studies of biology and drug design. These tools include small-molecule design, synthesis, derivatization, handling, and detection as well as advances in laboratory automation, robotics, and medicinal chemistry as applied to high-throughput screening (HTS). Methods for modification of proteins, nucleic acids, carbohydrates and lipids for their use as tools in the study of particular biological systems are also included
  • 2002- Wiley
    editorial board, Serge L. Beaucage ... [et al.].
  • 2010 Springer
    edited by Steven J. Shire, Genentech, Inc., San Francisco, CA USA, Wayne Gombotz, Omeros Corporation, Seattle, WA USA, Karoline Bechtold-Peters, Boehringer Ingelheim Pharma, Biberach, Germany, James Andya, Genentech, Inc., San Francisco, CA USA.
    Introduction / Wayne R. Gombotz and Steven J. Shire -- Design of therapeutic MABS. CDR repair: a novel approach to antibody humanization / Mark S. Dennis -- Nanobodies, single-domain antigen-binding fragments of camelid heavy-chain antibodies / Gholamreza Hassanzadeh Ghassabeh, Serge Muyldermans, and Dirk Saerens -- Expression and production of MABS. GPEx® a flexible method for the rapid generation of stable, high expressing, antibody producing mammalian cells lines / Gregory T. Bleck -- Advancing our cell culture platform: incorporating lessons learned and new technologies / Carole Heath -- Recovery and purification. Addressing changes associated with technology transfer: a case study / Michele M. Myers ... [et al.] -- Concepts for disposables in biopharmaceutical manufacture / Joachim K. Walter and Uwe Gottschalk -- Formulation and delivery. Formulation and delivery issues for monoclonal antibody therapeutics / Ann L. Daugherty and Randall J. Mrsny -- Challenges in the development of high protein concentration formulations / Steven J. Shire, Zahra Shahrock, and Jun Liu -- Protein immobilization by crystallization and precipitation: an alternative to lyophilization / Karoline Bechtold-Peters -- Analytics and specification setting for MABS. Characterizing high affinity antigen/antibody complexes by kinetic and equilibrium based methods / Andrew W. Drake, David G. Myszka, and Scott L. Klakamp -- Analytical characterization of monoclonal antibodies: linking structure to function / Reed J. Harris ... [et al.] -- Analysis of irreversible aggregation, reversible self-association and fragmentation of monoclonal antibodies by analytical ultracentrifugation / James D. Andya, Jun Liu, and Steven J. Shires -- Biophysical signatures of monoconal antibodies / N. Harn ... [et al.] -- Pharmacokinetics and immunogenicity. Impact of Fc glycosylation on monoclonal antibody effector functions and degradation by proteases / T. Shantha Raju -- Immunogenicity assessment of antibody therapeutics / P. stas, Y. Gansemans, and I. Lasters -- Armed antibodies and new classes of antibodies. Production of monoclonal antibodies in E. coli / Dorothea E. Reilly and Daniel G. Yansura -- Recent advances in the use of antibody drug conjugates for cancer theapy / Peter D. Senter -- Antibody radiolabeling / Corinne Bensimon and Russell Redshaw.
  • 2010 CRCnetBASE
    William S. Kisaalita.
    "This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
  • 2015 Springer
    Nikhil Balakrishnan.
    1. The Principles of Dependability -- 2. System Safety Assessment -- 3. Fault Tree Analysis -- 4. Failure Modes and Effects Analysis -- 5. Machine Learning Methods with Applications to Diagnosis -- 6. Byzantine Medical Problems: Decision Making with Misleading, Imperfect Information -- 7. Process Driven Methods in Diagnosis and Treatment -- 8. Toyota Production System -- 9. Reliance Implementation Methods Applied to a Kaizen Project -- 10. Knowledge & Culture.
  • 2013 Springer
    Volker A. Erdmann, Jan Barciszewski, editors.
    DNA and RNA nanobiotechnologies have currently reached the status of one of the most dynamic research areas in the field of drug delivery in molecular medicine. Scientists and bio-engineers are creating totally new nanometer-scale structures with unique biological properties for a wide range of medical applications. The book, written by world-leading scientists in this new field, gives an overview of various aspects and applications of DNA and RNA nanotechnologies. These include the design and synthesis of DNA and RNA nanostructures with the aim of using them for different kinds of drug deliveries, for genetic immunization, for metabolite and nucleic acid detection, gene regulation, siRNA delivery for cancer treatment, and even analytical and therapeutic applications of aptamer-based nanoparticles. This volume will be of interest not only to graduate students and researchers in the field of molecular medicine and molecular biology, but also to chemists interested in the biological fields. As a matter of fact, the book contains so many new and unique approaches to this area of molecular medicine that it may inspire the interested reader to undertake research into nucleic acid nanotechnologies.
  • 2012 Springer Protocols
    edited by Antonio Alonso.
    An overview of DNA typing methods for human identification : past, present, and future / Robyn Thompson, Silvia Zoppis, and Bruce McCord -- Capillary electrophoresis and 5-channel LIF detection of a 26plex autosomal STR asay for human identification / Carolyn R. Hill -- Capillary electrophoresis of miniSTR markers to genotype highly degraded DNA samples / Michael D. Coble -- Interpretation guidelines of a standard Y-chromosome STR 17-plex PCR-CE assay for crime casework / Lutz Roewer and Maria Geppert -- Capillary electrophoresis of an X-chromosome STR decaplex for kinship deficiency cases / Leonor Gusmão [and others] -- A 48-plex autosomal SNP GenPlex Assay for human individualization and relationship testing / Carmen Tomas, Claus Børsting, and Niels Morling -- Typing of 49 autosomal SNPs by single base extension and capillary electrophoresis for forensic genetic testing / Claus Børsting, Carmen Tomas, and Niels Morling -- A 34-plex autosomal SNP single base extension assay for ancestry investigations / C. Phillips, M. Fondevila, and Maria Victoria Lareau -- SNaPshot® minisequencing analysis of multiple ancestry-informative Y-SNPs using capillary electrophoresis / Maria Geppert and Lutz Roewer -- Capillary electrophoresis of 38 noncoding biallelic mini-indels for degraded samples and as complementary tool in paternity testing / Rui Pereira and Leonor Gusmão -- Capillary electrophoresis of an 11-plex mtDNA coding region SNP single base extension assay for discrimination of themost common caucasian HV1/HV2 mitotype / Peter M. Vallone -- Capillary electrophoresis of a multiplex reverse transcription-polymerase chain reaction to target messenger RNA markers for body fluid identification / Cordula Haas, Erin Hanson, and Jack Ballantyne -- DNA extraction from aged skeletal samples for STR typing by capillary electrophoresis / René Huel [and others] -- Interpretation guidelines for multilocus STR forensic profiles from low template DNA samples / Zoran M. Budimlija and Theresa A. Caragine -- Interpretation guidelines for mixed-STR multilocus electrophoretic profiles / Juan Antonio Luque -- Capillary electrophoresis analysis of a 9-plex STR assay for canine genotyping / Barbara van Asch and António Amorim -- Capillary electrophoresis of DNA from Cannabis sativa for correlation of samples to geographic origin / Heather Mller Coyle -- Capillary electrophoresis of multigene barcoding chloroplast markers for species identification of botanical trace evidence / Gianmarco Ferri, Beatrice Corradini, and Milena Alù -- Capillary electrophoresis of big-dye terminator sequencing reactions for human mtDNA control region haplotyping in the identification of human remains / Marta Montesino and Lourdes Prieto -- Capillary electrophoresis of human mtDNA control region sequences from highly degraded samples using short mtDNA amplicons / Odile M. Loreille and Jodi A. Irwin -- Interpretation guidelines of mt DNA control region sequence electropherograms in forensic gnetics / Manuel Crespillo Marquez -- Capillary electrophoresis of mtDNA cytochrome b gene sequences for animal species identification / Adrian Linacre -- Sequence analysis of the canine mitochondrial DNA control region from shed hair samples in criminal investigations / C. Berger, B. Berger, and W. Parson -- Integrated sample cleanup and microchip capillary array electrophoresis for high-performance forensic STR profiling / Peng Liu [and others] -- Microchip capillary electrophoresis protocol to evaluate quality and quantity of mtDNA amplified fragments for DNA sequencing in forensic genetics / Coro Fernández and Antonio Alonso -- Microchip capillary electrophoresis of multi-locus VNTR analysis for genotyping of Bacillus anthracis and Yersinia pestis in microbial forensic cases / Andrea Ciammaruconi.
  • 2011 Springer Protocols
    edited by Giampaolo Zuccheri and Bruno Samori.
    Synthesis and characterization of self-assembled DNA nanostructures / Chenxiang Lin [and others] -- Protocols for self-assembly and imaging of DNA nanostructures / Thomas L. Sobey and Friedrich C. Simmel -- Self-assembly of metal-DNA triangles and DNA nanotubes with synthetic junctions / Hua Yang [and others] -- DNA-templated Pd conductive metallic nanowires / Khoa Nguyen, Stephane Campidelli, and Arianna Filoramo -- Method to map spatiotemporal pH changes inside living cells using a pH-triggered DNA nanoswitch / Souvik Modi and Yamuna Krishnan -- Control of helical handedness in DNA and PNA nanostructures / Roberto Corradini [and others] -- G-quartet, G-quadruplex, and G-wire regulated by chemical stimuli / Daisuke Miyoshi and Naoki Sugimoto -- Preparation and atomic force microscopy of quadruplex DNA / James Vesenka -- Synthesis of long DNA-based nanowires / Alexander Kotlyar -- G-wire synthesis and modification with gold nanoparticle / Christian Leiterer, Andrea Csaki, and Wolfgang Fritzsche -- Preparation of DNA nanostructures with repetitive binding motifs by rolling circle amplification / Edda Rei⁷, Ralph Holzel, and Frank F. Bier -- Controlled confinement of DNA at the nanoscale : nanofabrication and surface bio-functionalization / Matteo Palma [and others] -- Templated assembly of DNA origami gold nanoparticle arrays on lithographically patterned surfaces / Albert M. Hung and Jennifer N. Cha -- DNA-modified single crystal and nanoporous silicon / Andrew Houlton [and others] -- Atomic force microscopy as a lithographic tool : nanografting of DNA nanostructures for biosensing applications / Matteo Castronovo and Denis Scaini -- Trapping and immobilization of DNA molecules between nanoelectrodes / Anton Kuzyk, J. Jussi Toppari, and Paivi Torma -- DNA contour length measurements as a tool for the structural analysis of DNA and nucleoprotein complexes / Claudio Rivetti -- DNA molecular handles for single-molecule protein-folding studies by optical tweezers / Ciro Cecconi [and others] -- Optimal practices for surface-tethered single molecule total internal reflection fluorescence resonance energy transfer analysis / Matt V. Fagerburg and Sanford H. Leuba -- Engineering mononucleosomes for single-pair FRET experiments / Wiepke J.A. Koopmans, Ruth Buning, and John van Noort -- Measuring DNA-protein binding affinity on a single molecule using optical tweezers / Micah J. McCauley and Mark C. Williams -- Modeling nanopores for sequencing DNA / Jeffrey R. Comer, David B. Wells, and Aleksei Aksimentiev.
  • 2014 Springer Protocols
    edited by Kewal K. Jain, Jan PharmaBiotech, Basel, Switzerland.
    Current Status and Future Prospects of Drug Delivery Systems -- A Method for Screening Mitochondrial Fusogenic Envelopes for use in Mitochondrial Drug Delivery -- Ultrasound-directed, Site-specific Gene Delivery -- Synthesis of Thermoresponsive Polymers for Drug Delivery -- Recombinant Stem Cells as Carriers for Cancer Gene Therapy -- Microfluidic-based Manufacture of siRNA-lipid Nanoparticles for Therapeutic Applications -- Microneedle-iontophoresis Combinations for Enhanced Transdermal Drug Delivery -- Polymer Nanoparticle-based Controlled Pulmonary Drug Delivery -- Antibody Labeling with Radioiodine and Radiometals -- Self Assembling Peptide -based Delivery of Therapeutics for Myocardial Infarction -- Applications of Chitosan Nanoparticles in Drug Delivery -- A Method for Evaluating Nanoparticle Transport through the Blood Brain Barrier in vitro -- Bacterial Systems for Gene Delivery to Systemic Tumours -- Synthesis of a Smart Nanovehicle for Targeting Liver -- Intranasal Delivery of Chitosan-siRNA Nanoparticle Formulation to the Brain -- Intrathecal Delivery of Analgesics.
  • 2013 Springer
    V. Sree Hari Rao, Ravi Durvasula, editors.
    This book covers modeling of insect vector-borne infectious diseases, which account for some three million deaths worldwide. The authors describe processes for quantifying the vital parameters of diseases transmitted by mosquitoes, sand flies, fleas and ticks. Despite great advances in public health worldwide, insect vector-borne infectious diseases remain a leading cause of morbidity and mortality. Diseases that are transmitted by arthropods such as mosquitoes, sand flies, fleas, and ticks affect hundreds of millions of people and account for nearly three million deaths all over the world. In the past there was very little hope of controlling the epidemics caused by these diseases, but modern advancements in science and technology are providing a variety of ways in which these diseases can be handled. Clearly, the process of transmission of an infectious disease is a nonlinear dynamic process which can be understood only by appropriately quantifying the vital parameters that govern these dynamics --c Source other than Library of Congress.
  • 2013 Springer
    V. Sree Hari Rao, Ravi Durvasula, editors.
    This book covers modeling of insect vector-borne infectious diseases, which account for some three million deaths worldwide. The authors describe processes for quantifying the vital parameters of diseases transmitted by mosquitoes, sand flies, fleas and ticks. Despite great advances in public health worldwide, insect vector-borne infectious diseases remain a leading cause of morbidity and mortality. Diseases that are transmitted by arthropods such as mosquitoes, sand flies, fleas, and ticks affect hundreds of millions of people and account for nearly three million deaths all over the world. In the past there was very little hope of controlling the epidemics caused by these diseases, but modern advancements in science and technology are providing a variety of ways in which these diseases can be handled. Clearly, the process of transmission of an infectious disease is a nonlinear dynamic process which can be understood only by appropriately quantifying the vital parameters that govern these dynamics.
  • 2009 Springer
    Alain Destexhe, Thierry Bal, editors.
  • 2005 Springer
    Valeria Matranga, (ed.).
    Are echinoderms of interest to biotechnology? / C. Petzelt -- Cell adhesion and communication : a lesson from echinoderm embryos for the exploitation of new therapeutic tools / F. Zito ... [et al.] -- Cell signalling during sea urchin development : a model for assessing toxicity of environmnetal contaminants / C. Angelini ... [et al.] -- Echinoderm reactive oxygen species (ROS) production measured by peroxidase, luminol-enhanced chemiluminescence (PLCL) as an immunotoxicological tool / G. Coteur, B. Danis, P. Dubois -- Monitoring chemical and physical stress using sea urchin immune cells / V. Matranga ... [et al.] -- DNA damage and developmental defects after exposure to UV and heavy metals in sea urchin cells and embryos compared to other invertebrates / H.C. Schröder ... [et al.] -- Echinoderms : their culture and bioactive compounds / M.S. Kelly -- Regenerative response and endocrine disrupters in crinoid echinoderms : an old experimental model, a new ecotoxicological test / M.D. Candia Carnevali -- Echinoderm adhesive secretions : from experimental characterization to biotechnological applications / P. Flammang, R. Santos, D. Haesaerts -- Mutable collagenous tissue : overview and biotechnological perspective / I.C. Wilkie -- Bioresources from echinoderms / Y. Yokota.
  • 2013 Springer
    Michael K. Danquah, Ram I. Mahato, editors.
  • 2006, 2010.
    John G. Webster, editor in chief.
  • 2014 Springer Protocols
    edited by Lianhong Sun, Wenying Shou.
    Recent progress in engineering human-associated microbiomes / Stephanie J. Yaung, George M. Church, and Harris H. Wang -- Constructing synthetic microbial communities to explore the ecology and evolution of symbiosis / Adam James Waite and Wenying Shou -- Combining engineering and evolution to create novel metabolic mutualisms between species / Lon Chubiz, Sarah Douglas, and William Harcombe -- Design, construction, and characterization methodologies for synthetic microbial consortia / Hans C. Bernstein and Ross P. Carlson -- An observation method for autonomous signaling-mediated synthetic diversification in Escherichia coli / Ryoji Sekine, Shotaro Ayukawa, and Daisuke Kiga -- Integration-free reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) without viral vectors, recombinant DNA, and genetic modification / Boon Chin Heng and Martin Fussenegger -- Transformation of Bacillus subtilis / Xiao-Zhou Zhang, Chun You, and Yi-Heng Percival Zhang -- Culturing anaerobes to use as a model system for studying the evolution of syntrophic mutualism / Sujung Lim, Sergey Stolyar, and Kristina Hillesland -- Therapeutic microbes for infectious disease / Choon Kit Wong [and six others] -- Quantitative measurement and analysis in a synthetic pattern formation multicellular system / Xiongfei Fu and Wei Huang -- Transcriptome analysis of a microbial coculture in which the cell populations are separated by a membrane / Kazufumi Hosoda [and three others] -- Identification of mutations in laboratory-evolved microbes from next-generation sequencing data using breseq / Daniel E. Deatherage and Jeffrey E. Barrick -- 3D-fluorescence in situ hybridization of intact, anaerobic biofilm / Kristen A. Brileya, Laura B. Camilleri, and Matthew W. Fields -- The characterization of living bacterial colonies using nanospray desorption electrospray ionization mass spectrometry / Brandi S. Heath, Matthew J. Marshall, and Julia Laskin -- Modeling community population dynamics with the open-source language R / Robin Green and Wenying Shou -- Simulating microbial community patterning using Biocellion / Seunghwa Kang, Simon Kahan, and Babak Momeni.
  • 2011 Atypon
    Monique Frize.
    Increasingly, biomedical scientists and engineers are involved in projects, design, or research and development that involve humans or animals. The book presents general concepts on professionalism and the regulation of the profession of engineering, including a discussion on what is ethics and moral conduct, ethical theories and the codes of ethics that are most relevant for engineers. An ethical decision-making process is suggested. Other issues such as conflicts of interest, plagiarism, intellectual property, confidentiality, privacy, fraud, and corruption are presented. General guidelines, the process for obtaining ethics approval from ethics Review Boards,and the importance of obtaining informed consent from volunteers recruited for studies are presented. A discussion on research with animals is included. Ethical dilemmas focus on reproductive technologies, stem cells, cloning, genetic testing, and designer babies. The book includes a discussion on ethics and the technologies of body enhancement and of regeneration. The importance of assessing the impact of technology on people, society, and on our planet is stressed. Particular attention is given to nanotechnologies, the environment, and issues that pertain to developing countries. Ideas on gender, culture, and ethics focus on how research and access to medical services have, at times, been discriminatory towards women. The cultural aspects focus on organ transplantation in Japan, and a case study of an Aboriginal child in Canada; both examples show the impact that culture can have on how care is provided or accepted. The final section of the book discusses data collection and analysis and offers a guideline for honest reporting of results, avoiding fraud, or unethical approaches. The appendix presents a few case studies where fraud and/or unethical research have occurred.
  • 2006
    edited by John E.J. Rasko, Gabrielle M. O'Sullivan, Rachel A. Ankeny.
    Status: Not Checked OutLane Catalog Record
    Foreword: Shopping at the genetic supermarket / Peter Singer -- Is inheritable genetic modification the new dividing line? / John E.J. Rasko ... [et al.] -- The science of inheritable genetic modification / John E.J. Rasko, Douglas J. Jolly -- Nuclear cloning, embryonic stem cells, and gene transfer / Rudolf Jaenisch -- Controlling bodies and creating monsters: popular perceptions of genetic modifications / Christoph Rehmann-Sutter -- Inheritable genetic modification as moral responsibility in a creative universe / Denis Kenny -- Ethics and welfare issues in animal genetic modification / Gabrielle M. O'Sullivan -- Radical rupture: exploring biologic sequelae of volitional inheritable genetic modification / Francoise Baylis, Jason Scott Robert -- "Alter-ing" the human species? Misplaced essentialism in science policy / Eric T. Juengst -- Traditional and feminist bioethical perspectives on gene transfer: is inheritable genetic modification really the problem? / Rosemarie Tong -- Inheritable genetic modification and disability: normality and identity / Jackie Leach Scully -- Regulating genetic modification: clinical applications and genetic counseling considerations / Joan A. Scott -- Can bioethics speak to politics about the prospect of inheritable genetic modification? If so, what might it say? / Roberta M. Berry -- Glossary of scientific terms / John E.J. Rasko ... [et al.].
  • 2009 Springer
    Jan Helge Solbakk, Søren Holm, Bjørn Hofmann, editors.
    Pt. 1. Research biobanking : the traditional approach -- Consent to biobank research : one size fits all? / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- What no one knows cannot hurt you : the limits of informed consent in the emerging world of biobanking / Arthur L. Caplan -- Users and uses of the biopolitics of consent : a study of DNA banks / Pascal Ducournau and Anne Cambon-Thomsen -- Information rights on the edge of ignorance / Anne Maria Skrikerud -- The dubious uniqueness of genetic information / Anne Maria Skrikerud -- Duties and rights of biobank participants : principled autonomy, consent, voluntariness and privacy / Lars Øystein Ursin -- Biobanking and disclosure of research results : addressing the tension between professional boundaries and moral intuition / Lynn G. Dressler -- Biobanks and our common good / Erik Christensen -- Trust, distrust and co-production : the relationship between research biobanks and donors / Pascal Ducournau and Roger Strand -- Scientific citizenship, benefit, and protection in population-based research / Vilhj́almur Árnason -- Pt. 2. Research Biobanking : towards a new conceptual approach -- Mapping the language of research biobanking : an analogical approach / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- The use of analogical reasoning in umbilical cord blood biobanking / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- The Alexandria plan : creating libraries for human tissue research and therapeutic use / Laurie Zoloth -- The art of biocollections / Anne Hambro Alnæs -- The health dugnard : biobank participation as the solidary pursuit of the common good / Lars Øystein Ursin and Berge Solberg -- Embodied gifting : reflections on the role of information in biobank recruitment / Klaus Hoeyer -- Conscription to biobank research? / Bjørn Hofmann, Jan Helge Solbakk, Søren Holm -- Ownership rights in research biobanks : do we need a new king of 'biological property'? / Paula Lobato de Faria -- Legal challenges and strategies in the regulation of research biobanking / Elisabeth Rynning -- Annexation of life : the biopolitics of industrial biology / Jan Reinert Karlsen and Roger Strand -- In the ruins of Babel : should biobank regulations be harmonized / Jan Reinert Karlsen, Jan Helge Solbak, and Roger Strand.
  • 2006 Springer
    by Martina Newell-McGloughlin and Edward Re.
  • 2011 Springer
    Peter T. Robbins, Farah Huzair, editors.
  • 2007 Springer
    editor, Shui Chuen Lee.
    Medicine and the biomedical technologies in the context of Asian perspectives / Shui Chuen Lee and Justin Ho -- Confucian familism and its bioethical implications / Ruiping Fan -- The family in transition and in authority: the impact of biotechnology / H. Tristram Engelhardt -- Family life, bioethics and Confucianism / Stephen A. Erickson -- The moral ground of truth telling guideline development: the choice between autonomy and paternalism / Shuh-Jen Sheu -- Truth telling to the sick and dying in a traditional Chinese culture / Stephen Wear -- On relational autonomy: from feminist critique to Confucian model for clinical practice / Shui Chuen Lee -- Regulating sex selection in a patriarchal society: lessons from Taiwan / Wenmay Rei -- Modern biotechnology and the postmodern family / Leonardo D. De Castro -- The ethics of human embryonic stem cell research and the interests of the family / Ruiping Fan -- A Confucian evaluation of embryonic stem cell research and the moral status of human embryos / Shui Chuen Lee -- Regulations for human embryonic stem cell research in East Asian countries: a Confucian critique / Hon Chung Wong -- Stem cell research: an Islamic perspective / Sahin Aksoy, Abdurrahman Elmali and Anwar Nasim -- Why Western culture, unlike Confucian culture, is so concerned about embryonic stem cell research: the Christian roots of the difference / H. Tristram Engelhardt -- Confucian healthcare system in Singapore: a family-oriented approach to financial sustainability / Kris Su Hui Teo -- Respect for the elderly and family responsibility: Confucian response to the old age allowance policy in Hong Kong / Erika H. Y. Yu -- Is Singapore's health care system congruent with Confucianism? / Justin Ho.
  • 2010 WHO
    "The advent of nanotechnology has unleashed enormous prospects for the development of new products and applications for a wide range of industrial and consumer sectors. The new technological developments have already opened up a multibillion dollar industry in recent years, the global market impact of which is expected to reach US$1 trillion by 2015, with around 2 million workers. While the majority of manufacturing and use of nanoscale materials occurs in the United States, the European Union, with its around 30 percent global share of the sector, is not lagging far behind in this field. Like other sectors, nanotechnology promises to revolutionize the whole food chain--from production to processing, storage, and development of innovative materials, products and applications. Although the potential applications of nanotechnoloy are wide ranging, the current applications in the food and agricultural sectors are relatively few, because the science is still newly emergent. An overview of more than 800 nanotechnology-based consumer products that are currently available worldwide, suggests that only around 10 percent of these are foods, beverages and food packaging products. However, nanotechnology-derived products and applications in these sectors have been steadily increasing in recent years, and are predicted to grow rapidly in the future. This is because the new technologies have a great potential to address many of the industry's current needs." - p. 3
    Also available: Print – 2010
  • 2006 Springer
    Hans-Joachim Bungartz, Michael Schäfer (eds.)
  • 2006 CRCnetBASE
    edited by Richard B. Thompson.
  • 2006 CRCnetBASE
    [edited by] Kalidas Shetty ... [et al.].
  • 2003 CRCnetBASE
    edited by Gustavo F. Gutiérrez-López, Gustavo V. Barbosa-Cánovas.
  • 2006 Springer Protocols
    edited by Catherine Adley.
    Detection of hemolysins in Aeromonas spp. isolates from food sources / Rosabel Falcón ... [et al.] -- Detection and purification of Bacillus cereus enterotoxins / Toril Lindbäck and Per Einar Granum -- Campylobacter / Rachel Gorman and Catherine C. Adley -- Detection of Clostridium botulinum by multiplex PCR in foods and feces / Miia Lindström, Mari Nevas, and Hannu Korkeala -- Multiplex PCR for the specific identification of enterohemorrhagic Escherichia coli strains in the O157:H7 complex / Peter C.H. Feng and Steven R. Monday -- Pulsenet's step-by-step laboratory protocol for molecular subtyping of Listeria monocytogenes by macrorestriction and pulsed-field gel electrophoresis / Lewis M. Graves and Balasubramanian Swaminathan -- Plesiomonas shigelloides / Ivan Ciznar ... [et al.] -- Pulsed-field gel electrophoresis as a molecular technique in Salmonella epidemiological studies / Rachel Gorman and Catherine C. Adley -- Kits for the detection of food poisoning toxins produced by Bacillus cereus and Staphylococcus aureus / Moira M. Brett -- Microbiological and molecular methods to identify and characterize toxigenic Vibrio cholerae from food samples / Keya De, Ranjan K. Nandy, and G. Balakrish Nair -- HPLC measurement of aflatoxin B1 and metabolites in isolated rat hepatocytes / Jennifer Colford -- Detection of noroviruses of genogroups I and II in drinking water by real-time one-step rRT-PCR / Christian M. Beuret -- Detection of enteroviruses / Miguel-Angel Jiménez-Clavero ... [et al.] -- Detection of hepatitis A virus and rotavirus using nucleic acid sequence-based amplification / Julie Jean and Ismaïl Fliss -- Isolation and characterization of cathepsin-L1 protease from Fasciola hepatica excretory/secretory products for the serodiagnosis of human fasciolosis / Sandra O'Neill, Grace Mulcahy, and John Dalton -- Molecular biology methods for detection and identification of Cryptososporidium species in feces, water and shellfish / C.J.P. Lowery ... [et al.] -- Molecular identification of nematode worms from seafood (Anisakis spp. and Pseudoterranova spp.) and meat (Trichinella spp.) / Giuseppe La Rosa, Stefano D'Amelio, and Eduardo Pozio -- Approaches to developing quantitative risk assessment models / Enda J. Cummins -- A review of surveillance networks of food-borne diseases / Camelia Molnar, Rita Wels, and Catherine C. Adley.
  • 2006 Springer
    2006 MyiLibrary
    Wan-Li Xing, Jing Cheng, editors.
  • 2005 Springer
    volume editors, Guillermo Orellana, Maria C. Moreno-Bondi ; with contributions by J. Alonso ... [et al.].
  • 2003 CRCnetBASE
    edited by Tiina Mattila-Sandholm and Maria Saarela.
    pt. 1. The health benefits of functional dairy products -- pt. 2. Functional dairy ingredients -- pt. 3. Product development.
  • 2007 CRCnetBASE
    edited by Kalidas Shetty ... [et al.].
  • 2013 Springer
    Ijeoma F. Uchegbu, Andreas G. Schätzlein, Woei Ping Cheng, Aikaterini Lalatsa, editors.
    Nanoscience and nanotechnology overview -- Liposome preparation and characterization -- Solid polymeric nanoparticles -- Lipid nanoparticles -- Polymeric vesicles -- Low molecular weight amphiphile micelles -- Polymeric micelles -- Niosomes -- Quantum dots -- Magnetic particles -- Drug nanoparticles -- Polymeric pro-drugs -- Therapeutic Applications of pharmaceutical nanosystems -- Drug solubilisation -- Gene therapy -- Chemotherapy -- Tissue engineering -- Anti-infectives -- Vaccination -- Anti-arthritic drugs -- Imaging agents -- Commercial exploitation of pharmaceutical nanosystems -- Future perspectives -- Multiple Choice -- Problem Sets -- Case Studies -- Suggested Reading.
  • 2009 Springer
    Ulrich Meyer, Thomas Meyer, Jörg Handschel, Hans Peter Wiesmann, (eds.).
  • 2011 CRCnetBASE
    William Wu, Helen H. Zhang, Michael J. Welsh, and Peter B. Kaufman.
    "The third edition of this popular reference covers a variety of techniques related to gene manipulation, including DNA isolation, preparation, screening, and analysis. Topics range from very basic methods to current and sophisticated technologies, including methodologies created and tested by the authors. Other topics include approaches to grant funding and SiRNA technology. The authors offer detailed, step-by-step explanations of protocols and helpful troubleshooting guides. This edition features new techniques for every chapter, as well as several new chapters"--Provided by publisher.
  • ScienceDirect
    edited by David V. Goeddel.
    Also available: Print – 1990
  • 2003 Wiley
    edited by Knut J. Heller.
    Part 1. Application and Perspectives -- ch. 1. Transgenic Modification of Production Traits in Farm Animals / Mathias Müller and Gottfried Brem -- ch. 2. Genetically Modified Plants / Susanne Stirn and Horst Lörz -- ch. 3. Fermented Food Production using Genetically Modified Yeast and Filamentous Fungi / Anke Niederhaus and Ulf Stahl -- ch. 4. Production of Food Additives using Filamentous Fungi / Carsten M. Hjort -- ch. 5. Perspectives of Genetic Engineering of Bacteria used in Food Fermentations / Arnold Geis -- Part II. Legislation in Europe -- ch. 6. The Legal Situation for Genetically Engineered Food in Europe / Rudolf Streinz and Lars O. Fuchs -- Part III. Methods of Detection -- ch. 7. Detection of Genetic Modifications: Some Basic Considerations / Knut J. Heller -- ch. 8. DNA-based Methods for Detection of Genetic Modifications / Ralf Einspanier and Stephanie Rief -- ch. 9. Genetic Engineering of Fishes and Methods for Detection / Hartmut Rehbein -- ch. 10. Detection Methods for Genetically Modified Crops / Rolf Meyer -- ch. 11. Methods to Detect the Application of Genetic Engineering in Composed and Processed Foods / Karl-Heinz Engel and Francisco Moreano -- ch. 12. Mutations in Lactococcus lactis, and their Detection / Jan Kok and Bertus van den Burg -- ch. 13. Detection Methods for Genetically Modified Microorganisms used in Food Fermentation / Walter P. Hammes, Christian Hertel and Torsten Bauer.
  • 2006 Wiley
    edited by Knut J. Heller.
    Part I. Application and Perspectives -- ch. 1. Transgenic modification of production traits in farm animals / Gottfried Brem, Mathias Müller -- ch. 2. Genetically modified plants / Susanne Stirn, Horst Lörz -- ch. 3. Fermentation of food by means of genetically modified yeast and filamentous fungi / Rena Leisegang, Elke Nevoigt, Anja Spielvogel, Georg Kristan, Anke Niederhaus, Ulf Stahl -- ch. 4. Production of food additives using filamentous fungi / Carsten M. Hjort -- ch. 5. Genetic engineering of bacteria used in food fermentation / Arnold Geis -- Part II. Legislation in Europe -- ch. 6. The Legal situation for genetically engineered food in Europe / Rudolf Streinz, Jan Kalbheim -- Part III. Methods of Detection -- ch. 7. Detection of genetic modifications : some basic considerations / Knut J. Heller -- ch. 8. DNA-based methods for detection of genetic modifications / Ralf Einspanier -- ch. 9. Genetic engineering of fish, and methods of detection / Hartmut Rehbein -- ch. 10. Detection methods for genetically modified crops / Rolf Meyer -- ch. 11. Methods for detection of genetically modified organisms in composite and processed foods / Karl-Heinz Engel, Francisco Moreano, Alexandra Ehlert -- ch. 12. Mutations in Lactococcus lactis and their detection / Jan Kok, Bertus van den Burg -- ch. 13. Methods for detection of genetically modified microorganisms used in food fermentation processes / Walter P. Hammes, Christian Hertel, Torsten Bauer.
  • maintained by HGMIS for the USDOE Human Genome Program.
  • 2013 Springer
    Jan Willem van der Laan, Joseph J. DeGeorge, editors.
    The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) is a unique project that brings together the regulatory authorities of Europe, Japan and the US and experts from the pharmaceutical industry in the three regions to discuss scientific and technical aspects of product registration. In Japan, the members are the Ministry of Health, Labour and Welfare (MHLW), and the Japan Pharmaceutical Manufacturers Association (JPMA). In Europe, the members are the EU (Representatives of the European Commission and the European Medicines Agency [EMA]), and the European Federation of Pharmaceutical Industries and Associations (EFPIA). In the United States, the members are the Food and Drug Administration (FDA), and the Pharmaceutical Research and Manufacturers of America (PhRMA). The International Federation of Pharmaceutical Manufacturers Associations (IFPMA) is the secretariat of the ICH. Additional members include Observers from WHO, European Free Trade Association (EFTA), and Canada. The Observers represent non-ICH countries and regions. This volume considers one of ICH's major categories, Safety, covering topics relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.). Since the start of the ICH process, many guidelines have been written, but in most cases there is a lack of awareness of the many issues that were addressed during the development of the consensus guidances. Further, just as it is important to understand what the guidances state, it is also important to understand the thoughts, debates, and intent of the experts involved, which are not included in the guidance documents. Why has the guideline been written as it is written, why are some topics ignored, and why have some initial guidance proposals have been deleted. These and other related questions and answers are the contents of this book, written by experts who were directly involved in writing the ICH guidances that drive drug development today.
  • 2006 Springer
    edited by Belinda Bennett and George F. Tomossy.
  • 2006 CRCnetBASE
    Kimball Nill.
  • 2002 CRCnetBASE
    Kimball Nill.
  • 2013 Springer Protocols
    edited by Alain Beck.
    Engineering of therapeutic and diagnostic o-glycans on recombinant mucin-type immunoglobulin fusion proteins expressed in CHO cel / Linda Lindberg, Jining Liu, and Jan Holgersson -- Engineering a human-like glycosylation to produce therapeutic glycoproteins based on 6-linked sialylation in CHO cells / Nassimal El Maï [and others] -- Glycoengineered pichia-based expression of monoclonal antibodies / Dongxing Zha -- N-glycosylation humanization for production of therapeutic recombinant glycoproteins in Saccharomyces cerevisiae / Christelle Arico, Christine Bonnet, and Christophe Javaud -- Engineering the baculovirus genome to produce galactosylated antibodies in lepidopteran cells / Sylvie Juliant [and others] -- NanoLC chips MS/MS for the characterization of n-glycopeptides generated from trypsin digestion of a monoclonal antibody / Elsa Wagner-Rousset [and others] -- Cetuximab Fab and Fc n-glycan fast characterization using IdeS digestion and liquid chromatography coupled to electrospray ionization mass spectrometry / Marie-Claire Janin-Bussat [and others] -- Therapeutic antibody glycosylation analysis : a contract research organization perspective in the frame of batch release or comparability support / Arnaud Delobel [and others] -- Mass spectrometric analysis of o-linked oligosaccharides from various recombinant expression systems / Diarmuid T. Kenny [and others] -- Assessing Fc glycan heterogeneity of therapeutic recombinant monoclonal antibodies using NP-HPLC / T. Shantha Raju -- Application of capillary electrophoresis in glycoprotein analysis / Richard R. Rustandi, Carrie Anderson, and Melissa Hamm -- Characterization of glycoprotein biopharmaceutical products by caliper LC90 CE-SDS gel technology / Grace Chen, Sha Ha, and Richard R. Rustandi -- Hydrophobic interaction chromatography to analyze glycoproteins / Richard R. Rustandi -- Lectin glycoprofiling of recombinant therapeutic interleukin-7 / Ludovic Landemarre and Eric Duverger -- Analysis of monoclonal antibodies by sedimentation velocity analytical ultracentrifugation / W. Blaine Stine Jr. -- Noncovalent mass spectrometry for the characterization of antibody/antigen complexes / Cédric Atmanene [and others] -- Conformational analysis of recombinant monoclonal antibodies with hydrogen/deuterium exchange mass spectrometry / Damian Houde and John R. Engen -- Epitope mapping of antibodies by mass spectroscopy : a case study / Victor H. Obungu, Valentina Gelfanova, and Lihua Huang -- Evaluation of antibody-dependent cell cytotoxicity using lactate dehydrogenase (LDH) measurement / Matthieu Broussas, Lucile Broyer, and Liliane Goetsch -- Evaluation of complement-dependent cytotoxicity using ATP measurement and C1q/C4b binding / Lucile Broyer, Liliane Goetsch, and Matthieu Broussas -- Capture of the human IgG1 antibodies by protein A for the kinetic study of h-IgG/FcgR interaction using SPR-based biosensor technology / Thierry Champion and Alain Beck -- Mass spectrometry protocol for the absolute quantification of a monoclonal antibody in serum with immunopurification / François Becher [and others].
  • 2007 Springer
    editors, H.R. Bourne, R. Horuk, J. Kuhnke, H. Michel.
  • 2009 ScienceDirect
    edited by Richard R. Burgess, Murray P. Deutscher.
    Also available: Print – 2009
  • 2005 CRCnetBASE
    edited by Kevin J. Yarema.
  • 2005 CRCnetBASE
    edited by Lothar Eggeling, Michael Bott.
  • 2009 CRCnetBASE
    editor, Annie Cavalier, Danièle Spehner, and Bruno M. Humbel.
    Vitreous water / Jacques Dubochet -- Slam-freezing, metal-mirror freezing / Danièle Spehner and Ludwig Edelmann -- Plunge-freezing (Holey carbon method) / Sacha De Carlo -- Controlled vitrification / Peter M. Frederik, Felix de Haas, and Marc M.H. Storms -- BAL-TEC HPM 010 high-pressure freezing machine / Andres Kaech -- High-pressure freezing LEICA EMPACT / Dimitri Vanhecke and Daniel Studer -- Frozen-hydrated macromolecules for structural analysis / Corinne Crucifix, Gabor Papai, and Patrick Schultz -- 2-D crystals / Patrick Bron and Janet Vonck -- Cryo-negative staining / Sacha De Carlo -- Vitrification of dynamic microtubules / Isabelle Arnal, Marine Malleter, and Denis Chrétien -- CEMOVIS : cryo-electron microscopy of vitreous sections / Jacques Dubochet ... [et al.] -- Cryo-electron tomography / Andrew Leis, Manuela Gruska, and Wolfgang Baumeister -- Freeze-substitution / Bruno M. Humbel -- Cryo-fixation, freeze-substitution, rehydration and Tokuyasu cryo-sectioning / York-Dieter Stierhof ... [et al.] -- Freeze-drying and embedding of biological material / Ludwig Edelmann -- The shadow of hydrated biological specimens / Daniel Thomas -- Cryo-fracture of self assembled systems in organic solvent / Marc Schmutz and Philippe J. Mésini -- Progressive lowering of temperature for immunolabeling and in situ hybridization / Annie Cavalier and Danièle Spehner -- Cryo-sectioning according to Tokuyasu / Bruno M. Humbel and York-Dieter Stierhof -- Cryo-preparation procedures for elemental imaging by SIMS and EFTEM / Christian Bordat and Jean-luc Guerquin-Kern -- Correlative light and electron microscopy / Heinz Schwarz and Bruno M. Humbel -- SDS-digested freeze-fracture replica labeling (SDS-FRL) / Yugo Fukazawa ... [et al.] -- Immunolabeling of ultra-thin sections with enlarged 1 nm gold or QDots / York-Dieter Stierhof -- 3-D electron tomography of cells and organelles / Willie J.C. Geerts, Bruno M. Humbel and Arie J. Verkleij -- Final considerations / Hellmuth Sitte.
  • 2007 CRCnetBASE
    edited by Shyam S. Sablani ... [et al.].
    Mathematical modeling techniques in food and bioprocessing: an overview / Ashim K. Datta and Shyam S. Sablani -- Lattice Boltzmann modeling / R.G.M. van der Sman -- Fluid flow and computational fluid dynamics / Ashwini Kumar and Ilhan Dilber -- Heat transfer / Ashim K. Datta -- Mass transfer: membrane processes / David Hughes, Taha Taha, and Zhanfeng Cui -- Heat and mass transfer / X. Dong Chen -- Reaction kinetics / Maria C. Giannakourou and Petros S. Taoukis -- Probabilistic modeling / Bart M. Nicolai, Nico Scheerlinck, and Maarten Hertog -- Experimental design and response surface methodology / Shuryo Nakai, Eunice C.Y. Li-Chan, and Jinglie Dou -- Multivariate analysis / Ioannis S. Arvanitoyannis -- Data mining / Geoffrey Holmes -- Artificial neural network modeling / Shyam S. Sablani -- Genetic algorithm / T. Morimoto -- Fractal analysis / M. Shafiur Rahman -- Fuzzy modeling / Haitham M. S. Lababidi and Christopher G. J. Baker -- Monte-Carlo simulation / Kevin Cronin & James P. Gleeson -- Dimensional analysis / Law C. Lim, Shyam S. Sablani, and Arun S. Mujumdar -- Linear programming / Eli Feinerman and Sam Saguy.
  • 2005 CRCnetBASE
    edited by Zhiqiang An.
  • 2009 CRCnetBASE
    edited by Anil K. Pabby, Syed S.H. Rizvi, Ana Maria Sastre.
  • 2008
    by Kewal K. Jain.
    Status: Not Checked OutLane Catalog Record
  • v.1-4=, 2014 Wiley
    edited by Stefan Dubel and Janice M. Reichert.
    Volume 1. Defining the Right Antibody Composition -- Volume 2. Clinical Development of Antibodies -- Volume 3. Approved Therapeutic Antibodies -- Volume 4. Approved Therapeutic Antibodies and in vivo Diagnostics.
  • 2015 Springer
    Kazuyuki Akasaka, Hitoshi Matsuki, editors.
    Part I. Why and how proteins denature under prssure? -- Part II. Volume, compressibility, fluctuation and interaction in proteins -- Part III. Pressure and functional sub-states in proteins -- Part IV. Pressure and protein folding and assembly -- Part V. Pressure effects on biological membranes -- Part VI. Pressure adaptation and tolerance of proteins and living organisms -- Part VII. High pressure food processing and sterilization -- Part VIII. Pressure effects on motility, physiology and health -- Part IX. Methodology.
  • 2014 Springer Protocols
    edited by Yacine Graba, René Rezsohazy.
    Discovery and classification of homeobox genes in animal genomes / Ferdinand Marlétaz, Jordi Paps, Ignacio Maeso, and Peter W. H. Holland -- How to study hox gene expression and function in mammalian oocytes and early embryos / Delphine Paul, Caroline Sauvegarde, René Rezsohazy, and Isabelle Donnay -- Genetic lineage tracing analysis of anterior hox expressing cells / Brigitte Laforest, Nicolas Bertrand, and Stéphane Zaffran -- A genetic strategy to obtain P-Gal4 elements in the Drosophila hox genes / Luis de Navas, David Foronda, Delia del Saz, and Ernesto Sánchez-Herrero -- Hox complex analysis through BAC recombineering / Mark Parrish, Youngwook Ahn, Christof Nolte, Bony De Kumar and Robb Krumlauf -- The genetics of murine Hox loci : TAMERE, STRING, and PANTHERE to engineer chromosome variants / Patrick Tschopp and Denis Duboule -- Topological organization of Drosophila hox genes using DNA fluorescent in situ hybridization / Frédéric Bantignies and Giacomo Cavalli -- Mining the Cis-regulatory elements of hox clusters / Navneet Kaur Matharu and Rakesh K. Mishra -- Functional analysis of hox genes in Zebrafish / Franck Ladam and Charles G. Sagerström -- Transgenesis in non-model organisms : the case of Parhyale / Zacharias Kontarakis and Anastasios Pavlopoulos -- Tissue specific RNA isolation in Drosophila embryos : a strategy to analyze context dependent transcriptome landscapes using FACS / Arnaud Defaye and Laurent Perrin -- Hox transcriptomics in Drosophila embryos / Maria Polychronidou and Ingrid Lohmann -- Measuring hox-DNA binding by electrophoretic mobility / Kelly Churion [and four others] -- Chromatin immunoprecipitation and chromatin immunoprecipitation with massively parallel sequencing on mouse embryonic tissue / Shilu Amin and Nicoletta Bobola -- chIP for hox proteins from Drosophila imaginal discs / Pavan Agrawal and L. S. Shashidhara -- SELEX-seq : a method for characterizing the compete repertoire of binding site preferences for transcription factor complexes / Todd R. Riley [and six others] -- DamID as an approach to studyinhg long-distance chromatin iteractions / Fabienne Cléard, François Karch, and oRbert K. Maeda -- cgCHIP : a cell type- and gene-specific method for chromatin analysis / Marios Agelopoulos, Daniel J. McKay, and Ricahrd S. Mann -- Bimolecular fluorescence complementation (biFC) in live Drosophila embryos / Marilyne Duffraisse, Bruno Hudry, and Samir Merabet -- Rational drug repurposing using sscMap analysis in a HOX-TALE model of leukemia / Laura M. Kettyle, Fabio G. Liberante, and Alexander Thompson.
  • 2013 Springer Protocols
    edited by Kursad Turksen.
    Primary Culture and Live Imaging of Adult Neural Stem Cells and Their Progeny / Felipe Ortega, Benedikt Berninger, and Marcos R. Costa -- Labeling and Tracking of Human Mesenchymal Stem Cells Using Near-Infrared Technology / Marie-Therese Armentero, Patrizia Bossolasco, and Lidia Cova -- High Content Imaging and Analysis of Pluripotent Stem Cell-Derived Cardiomyocytes / Gábor Földes and Maxime Mioulane -- A High Content Imaging-Based Approach for Classifying Cellular Phenotypes / Joseph J. Kim, Sebastián L. Vega, and Prabhas V. Moghe -- Conversion of Primordial Germ Cells to Pluripotent Stem Cells: Methods for Cell Tracking and Culture Conditions / Go Nagamatsu and Toshio Suda -- Imaging and Tracking of Bone-Marrow-Derived Immune and Stem Cells / Youbo Zhao [and four others] -- Co-Visualization of Methylcytosine, Global DNA, and Protein Biomarkers for In Situ 3-D DNA Methylation Phenotyping of Stem Cells / Jian Tajbakhsh -- Noninvasive Imaging of Myocardial Blood Flow Recovery in Response to Stem Cell Intervention / HuaLei Zhang and Rong Zhou -- Live Imaging of Early Mouse Embryos Using Fluorescently Labeled Transgenic Mice / Takaya Abe, Shinichi Aizawa, and Toshihiko Fujimori -- Live Imaging, Identifying, and Tracking Single Cells in Complex Populations In Vivo and Ex Vivo / Minjung Kang [and four others] -- Quantitative Evaluation of Stem Cell Grafting in the Central Nervous System of Mice by In Vivo Bioluminescence Imaging and Postmortem Multicolor Histological Analysis / Kristien Reekmans [and eight others] -- Micro-CT Technique for Three Dimensional Visualization of Human Stem Cells / Andrea Farini [and four others] -- Noninvasive Multimodal Imaging of Stem Cell Transplants in the Brain Using Bioluminescence Imaging and Magnetic Resonance Imaging / Annette Tennstaedt [and three others] -- Magnetic Resonance Imaging and Tracking of Stem Cells / Hossein Nejadnik, Rostislav Castillo, and Heike E. Daldrup-Link -- Whole Body MRI and Fluorescent Microscopy for Detection of Stem Cells Labeled with Superparamagnetic Iron Oxide (SPIO) Nanoparticles and DiI Following Intramuscular and Systemic Delivery / Boris Odintsov, Ju Lan Chun, and Suzanne E. Berry -- Molecular Imaging and Tracking Stem Cells in Neurosciences / Toma Spiriev, Nora Sandu, and Bernhard Schaller -- Bioluminescence Imaging of Human Embryonic Stem Cells-Derived Endothelial Cells for Treatment of Myocardial Infarction / Weijun Su [and four others].
  • 2006 Springer Protocols
    edited by Jose M. Guisan.
  • 2013 Springer Protocols
    edited by Jose M. Guisan.
    New opportunities for immobilization of enzymes / Jose M. Guisan -- Immobilization of enzymes : a literature survey / Beatriz Brena, Paula González-Pombo, and Francisco Batista-Viera -- Glutaraldehyde-mediated protein immobilization / Fernando López-Gallego, Jose M. Guisán, and Lorena Betancor -- Immobilization of enzymes on monofunctional and heterofunctional epoxy-activated supports / Cesar Mateo, Valeria Grazu, and Jose M. Guisan -- Stabilization of enzymes by multipoint covalent immobilization on supports activated with glyoxyl groups / Fernando López-Gallego ... [et al.] -- Oriented covalent immobilization of enzymes on heterofunctional-glyoxyl supports / Cesar Mateo ... [et al.] -- Reversible covalent immobilization of enzymes via disulfide bonds / Karen Ovsejevi, Carmen Manta, and Francisco Batista-Viera -- Immobilization of Candida rugosa lipase on superparamagnetic Fe3O4 nanoparticles for biocatalysis in low-water media / Joyeeta Mukherjee, Kusum Solanki, and Munishwar Nath Gupta -- Immobilization of enzymes by bioaffinity layering / Veena Singh, Meryam Sardar, and Munishwar Nath Gupta -- Immobilization of enzymes on magnetic beads through affinity interactions / Audrey Sassolas, Akhtar Hayat, and Jean-Louis Marty -- Tips for the functionalization of nanoparticles with antibodies / Ester Polo ... [et al.] -- Design and characterization of functional nanoparticles for enhanced bio-performance / Pablo del Pino, Scott G. Mitchell, and Beatriz Pelaz -- Immobilization of enzymes on ethynyl-modified electrodes via click chemistry / Akhtar Hayat ... [et al.] -- Modification of carbon nanotube electrodes with 1-pyrenebutanoic acid, succinimidyl ester for enhanced bioelectrocatalysis / Guinevere Strack ... [et al.] -- Enzyme immobilization by entrapment within a gel network / Audrey Sassolas, Akhtar Hayat, and Jean-Louis Marty -- Practical protocols for lipase immobilization via sol-gel techniques / Manfred T. Reetz -- Improving lipase activity by immobilization and post-immobilization strategies / Jose M. Palomo ... [et al.] -- High activity preparations of lipases and proteases for catalysis in low water containing organic solvents and ionic liquids / Ipsita Roy ... [et al.] -- Biomedical applications of immobilized enzymes : an update / Marta Pastor, Amaia Esquisabel, and José Luis Pedraz -- Immobilization of whole cells by chemical vapor deposition of silica / Susan R. Sizemore ... [et al.] -- Encapsulation of cells in alginate gels / Pello Sánchez ... [et al.] -- Microalgal immobilization methods / Ignacio Moreno-Garrido -- Therapeutic applications of encapsulated cells / Argia Acarregui ... [et al.] -- Whole cell entrapment techniques / Jorge A. Trelles and Cintia W. Rivero.
  • 2015 Springer
    John D. Lambris, Kristina N. Ekdahl, Daniel Ricklin, Bo Nilsson, editors.
    1. Thromboinflammation in therapeutic medicine -- 2. Complement interactions with blood cells, endothelial cells and microvesicles in thrombotic and inflammatory conditions -- 3. Role of complement on broken surfaces after trauma -- 4. Complement involvement in periodontitis: molecular mechanisms and rational therapeutic approaches -- 5. The lectin pathway of complement and biocompatibility -- 6. Foreign body reaction to subcutaneous implants -- 7. Molecular characterization of macrophage-biomaterial interactions -- 8. Heparan sulfate proteoglycan metabolism and the fate of grafted tissues -- 9. Xenotransplantation of cells, tissues, organs and the Greman research foundation Transregio Collaborative Research Centre 127 -- 10. Macroencapsulated pig islets correct induced diabetes in primates up to 6 months -- 11. Regulation of instant blood mediated inflammatory reaction (IBMIR) in pancreatic islet xeno-transplantation: points for therapeutic interventions -- 12. Cell surface engineering for reguation of immune reactions in cell therapy -- 13. Complement interception across humoral incompatibility in solid organ transplantation: a clinical perspective -- Index.
    Also available: Print – 2015
  • 2013 Springer
    Paul J. Fairchild, editor.
    Recent years have witnessed numerous advances in stem cell research that have suggested novel strategies for the treatment of the chronic and regenerative diseases that pose a growing challenge to the provision of healthcare in the 21<sup>st</sup> century. Nevertheless, there is little doubt that related disciplines have failed to keep pace with such developments, of which the immunology of transplant rejection is perhaps the most relevant to the nascent field of regenerative medicine. Indeed, given that after decades of research into the mechanisms of organ allograft rejection, we remain wholly dependent on immune suppression to ensure acceptance of foreign tissues, we might legitimately ask whether there is any reason why tissues differentiated from stem cells might not suffer the same fate. This volume seeks to address this issue by drawing on the principles of alloantigen recognition to assess the validity of early convictions that embryonic stem cell-derived tissues may prove invisible to the immune system of the host and the more recent belief that induced pluripotent stem cells, derived in a fully autologous manner, will circumvent the issue of immunogenicity. Having debunked such assumptions and established the magnitude of the immunological barriers to be overcome, this book then draws on the expertise of internationally-recognised laboratories around the world to provide a critical assessment of the likely success of applying strategies such as stem cell banking, silencing of genes that confer immunogenicity, and the induction of transplantation tolerance to overcoming the immunological barriers in the future. Indeed, it is only through reaching a consensus in the field that enduring solutions to such an intractable problem may ultimately emerge.
  • 2014 Wiley
    edited by Evgeny Katz.
  • 2013 Springer
    David Korpas.
    History and development of pacing -- Basic principles of cardiac pacemaker technology -- Heart anatomy and physiology -- Pharmacological treatment of cardiac rhythm disorders -- Pacing modes -- Indications for implantable system treatment -- Leads -- Pacing systems -- Pacemaker timing -- Implantable cardioverter-defibrillators -- Cardiac resynchronization therapy -- Implantation, explantation, and replacement of devices and leads -- Patient follow-up -- Electromagnetic compatibility and technical requirements.
  • 2012 Springer
    Sibel Yildirim.
  • 2003 ScienceDirect
    edited by W.Y. Aalbersberg ... [et al.].
  • 2015 Springer Protocols
    edited by Elena García-Fruitós.
    General introduction : recombinant protein production and purification of insoluble proteins / Neus Ferrer-Miralles ... [et al.] -- Overcoming the solubility problem in E. coli : available approaches for recombinant protein production / Agustín Correa and Pablo Oppezzo -- Optimization of culture parameters and novel strategies to improve protein solubility / Ranjana Arya ... [et al.] -- Cleavable self-aggregating tags (cSAT) for protein expression and purification / Zhanglin Lin ... [et al.] -- Beyond the cytoplasm of Escherichia coli : localizing recombinant proteins where you want them / Jason T. Boock ... [et al.] -- Characterization of amyloid-like properties in bacterial intracellular aggregates / Anna Villar-Pique, Susanna Navarro, and Salvador Ventura -- Co-translational stabilization of insoluble proteins in cell- free expression systems / Lei Kai ... [et al.] -- Functional expression of plant membrane proteins in Lactococcus lactis / Sylvain Boutigny .... [et al.] -- High cell-density expression system : yeast cells in a phalanx efficiently produce a certain range of "Difficult-to-Express" secretory recombinant proteins / Yasuaki Kawarasaki, Takeshi Kurose, and Keisuke Ito -- Insect cells-baculovirus system for the production of difficult to express proteins / Judit Osz-Papai ... [et al.] -- Transient expression in HEK 293 cells : an alternative to E. coli for the production of secreted and intracellular mammalian proteins / Joanne E. Nettleship ... [et al.] -- Recombinant glycoprotein production in human cell lines / Kamilla Swiech ... [et al.] -- Soluble recombinant protein production in Pseudoalteromonas haloplanktis TAC125 / Maria Giuliani ... [et al.] -- Screening methodology for purifying proteins with aggregation problems / Mario Lebendiker, Michal Maes, and Assaf Friedler -- Solubilization and refolding of inclusion body proteins / Anupam Singh, Vaibhav Upadhyay, and Amulya K. Panda -- Bacterial inclusion body purification / Joaquin Seras-Franzoso ... [et al.] -- Characterization of intracellular aggresomes by fluorescent microscopy / Lianwu Fu and Elizabeth Sztul -- Dialysis : a characterization method of aggregation tendency / Mireia Pesarrodona, Ugutz Unzueta, and Esther Vázquez -- Applications of mass spectrometry to the study of protein aggregation / Sílvia Bronsoms and Sebastián A. Trejo -- Insoluble protein assemblies characterized by Fourier transform infrared spectroscopy / Antonino Natalello and Silvia M. Doglia -- Insoluble protein characterization by circular dichroism (CD) spectroscopy and nuclear magnetic resonance (NMR) / Shaveta Goyal ... [et al.] -- Methods for characterization of protein aggregates / Witold Tatkiewicz ... [et al.] -- Predicting the solubility of recombinant proteins in Escherichia coli / Roger G. Harrison and Miguel J. Bagajewicz -- Insoluble protein applications : the use of bacterial inclusion bodies as biocatalysts / Eva Hrabárová , Lucia Achbergerová , and Jozef Nahálka.
  • 2012 Wiley
    edited by Murugan Ramalingam [and others].
  • 2014 Springer
    Joanna T. Brougher.
    Introduction to intellectual property -- Obtaining, enforcing and defending patents -- The patent-eligibility of genes -- Medical procedure patents -- Rights and roles of universities and inventors -- Drug development : balancing innovation, access and profits -- Patent battles part I : small-molecule drugs -- Patent battles part II : the Biosimilars Act and biologics -- International patent law, trade law, and access to drugs.
  • 2012 Wiley
    edited by Marcus Textor, H. Michelle Grandin.
    Frontmatter -- Color Plates -- Stimulus-Responsive Polymers as Intelligent Coatings for Biosensors: Architectures, Response Mechanisms, and Applications / Vinalia Tjong, Jianming Zhang, Ashutosh Chilkoti, Stefan Zauscher -- Smart Surfaces for Point-of-Care Diagnostics / Michael A Nash, Allison L Golden, John M Hoffman, James J Lai, Patrick S Stayton -- Design of Intelligent Surface Modifications and Optimal Liquid Handling for Nanoscale Bioanalytical Sensors / Laurent Feuz, Fredrik H̲̲k, Erik Reimhult -- Intelligent Surfaces for Field-Effect Transistor-Based Nanobiosensing / Akira Matsumoto, Yuji Miyahara, Kazunori Kataoka -- Supported Lipid Bilayers: Intelligent Surfaces for Ion Channel Recordings / Andreas Janshoff, Claudia Steinem -- Antimicrobial and Anti-Inflammatory Intelligent Surfaces / Hans J Griesser, Heike Hall, Toby A Jenkins, Stefani S Griesser, Krasimir Vasilev -- Intelligent Polymer Thin Films and Coatings for Drug Delivery / Alexander N Zelikin, Brigitte St̃dler -- Micro- and Nanopatterning of Active Biomolecules and Cells / Daniel Aydin, Vera C Hirschfeld-Warneken, Ilia Louban, Joachim P Spatz -- Responsive Polymer Coatings for Smart Applications in Chromatography, Drug Delivery Systems, and Cell Sheet Engineering / Roǧrio P Pirraco, Masayuki Yamato, Yoshikatsu Akiyama, Kenichi Nagase, Masamichi Nakayama, Alexandra P Marques, Rui L Reis, Teruo Okano -- Index.
  • 2003 Wiley
    Paras N. Prasad.
    ch. 1. Introduction -- ch. 2. Fundamentals of Light and Matter -- ch. 3. Basics of Biology -- ch. 4. Fundamentals of Light-Matter Interactions -- ch. 5. Principles of Lasers, Current Laser Technology, and Nonlinear -- ch. 6. Photobiology -- ch. 7. Bioimaging: Principles and Techniques -- ch. 8. Bioimaging: Applications -- ch. 9. Biosensors -- ch. 10. Microarray Technology for Genomics and Proteomics -- ch. 11. Flow Cytometry -- ch. 12. Light-Activated Therapy: Photodynamic Therapy -- ch. 13. Tissue Engineering with Light -- ch. 14. Laser Tweezers and Laser Scissors -- ch. 15. Nanotechnology for Biophotonics: Bionanophotonics -- ch. 16. Biomaterials for Photonics.
  • 2009 Springer
    Alexander P. Demchenko.
  • 2003 CRCnetBASE
    edited by Rajni Hatti-Kaul, Bo Mattiasson.
  • 2013 Springer
    Fabio Catani, Stefano Zaffagnini, editors.
    This book discusses the full range of current applications of computer-assisted surgery and robotics in the field of knee surgery, and also considers potential future applications. The impact of computer-assisted surgery on a wide range of surgical procedures is clearly explained. Procedures considered include total knee arthroplasty, unicompartmental knee arthroplasty, cruciate ligament reconstruction, patellofemoral arthroplasty, and revision surgery. In each case, technical aspects are thoroughly addressed in a readily understandable manner. Knee Surgery Using Computer-Assisted Surgery and Robotics will be an ideal guide to this exciting field for both novice and more experienced surgeons who treat knee injuries and disorders.
  • 2013 ScienceDirect
    edited by Jon Lorsch.
    Section I. Cell protocols : basic microbiological techniques. Pouring agar plates and streaking or spreading to isolate individual colonies / Elizabeth Eyler ; Storage of bacteria and yeast / Cheryl M. Koh -- Section II. Cell protocols : cellular fractionation. Cellular fractionation : mammalian cells / Joerg von Hagen and Uwe Michelsen ; Cellular fractionation : yeast cells / Joerg von Hagen and Uwe Michelsen -- Section III. Cell protocols : Knock-outs and gene replacements. Yeast-gene replacement using PCR products / Megan Bergkessel, Christine Guthrie, and John Abelson ; Measuring RNAi knockdown using qPCR / Stuart Milstein, Michael Nguyen, Rachel Meyers, and Antonin de Fougerolles ; Recombineering : using drug cassettes to knock out genes in vivo / James A. Sawitzke, Lynn C. Thomason, Mikhail Bubunenko, Xintian Li, Nina Costantino, and Donald L. Court ; Gene knockouts, in vivo site-directed mutagenesis and other modifications using the delitto perfetto system in Saccharomyces cerevisiae / Samantha Stuckey and Francesca Storici ; Gene targeting and site-specific recombination in mouse ES cells / Konstantinos Anastassiadis, Frank Schnütgen, Harald von Melchner, and A. Francis Stewart ; Recombineering : highly efficient in vivo genetic engineering using single-strand oligos / James A. Sawitzke, Lynn C. Thomason, Mikhail Bubunenko, Xintian Li, Nina Costantino, and Donald L. Court -- Section IV. Cell protocols : microbiological media. Growth media for E. coli / Juliane C. Lessard ; Saccharomyces cerevisiae growth media / Jessica S. Dymond --Section V. Cell protocols : preparation of slides for microscopy. Immunohistochemistry on freely floating fixed tissue sections / Julia Bachman ; Preparation of slides for microscopy from frozen tissue sections / Julia Bachman ; Preparation of formalin-fixed paraffin-embedded tissue for immunohistochemistry / Kirstie Canene-Adams ; Preparation of cells for microscopy using cytospin / Cheryl M. Koh ; Preparation of cells for microscopy using chamber slides and coverslips / Cheryl M. Koh ; Preparation of cells for microscopy using 'cell blocks' / Cheryl M. Koh -- Section VI. Lipid and carbohydrate protocols. Enzymatic deglycosylation of glycoproteins / Min-Sung Kim and Dan Leahy -- Section VII. Lipid and carbohydrate protocol : making vesicles and micelles. Preparation of fatty acid or phospholipid vesicles by thin-film rehydration / Ting F. Zhu, Itay Budin, and Jack W. Szostak ; Vesicle extrusion through polycarbonate track-etched membranes using a hand-held mini-extruder / Ting F. Zhu, Itay Budin, and Jack W. Szostak ; Preparation of fatty acid micelles / Ting F. Zhu, Itay Budin, and Jack W. Szostak -- Section VIII. Other protocols. Reverse-phase HPLC analysis and purification of small molecules / Kirstie Canene-Adams ; Thin layer chromatography / Marina Santiago and Scott Strobel ; ATP and GTP hydrolysis assays (TLC) / Vaishnavi Rajagopal and Jon R. Lorsch.
  • 2013 ScienceDirect
    edited by Jon Lorsch.
    Explanatory chapter: PCR primer design / Rubén Álvarez-Fernández -- How plasmid preparation kits work / Laura Koontz -- Introducing exogenous DNA into cells / Laura Koontz -- Agarose gel electrophoresis / Laura Koontz -- Analysis of DNA by southern blotting / Gary Glenn and Lefkothea-Vasiliki Andreou -- Purification of DNA oligos by denaturing polyacrylamide gel electrophoresis (PAGE) / Sara Lopez-Gomollon and Francisco Esteban Nicolas -- Molecular cloning / Juliane C. Lessard -- Rapid creation of stable mammalian cell lines for regulated expression of proteins using the Gateway® recombination cloning technology and Flp-In T-REx® lines / Jessica Spitzer, Markus Landthaler, and Thomas Tuschl -- Restrictionless cloning / Mikkel A. Algire -- Isolation of plasmid DNA from bacteria / Lefkothea-Vasiliki Andreou -- Preparation of genomic DNA from bacteria / Lefkothea-Vasiliki Andreou -- Preparation of genomic DNA from Saccharomyces cerevisiae / Jessica S. Dymond -- Isolation of genomic DNA from mammalian cells / Cheryl M. Koh -- Sanger dideoxy sequencing of DNA / Sarah E. Walker and Jon Lorsch -- Preparation of fragment libraries for next-generation sequencing on the applied biosystems SOLiD platform / Srinivasan Yegnasubramanian -- Next generation sequencing / Srinivasan Yegnasubramanian -- Generating mammalian stable cell lines by electroporation / Patti A. Longo, Jennifer M. Kavran, Min-Sung Kim, and Daniel J. Leahy -- Transient mammalian cell transfection with polyethylenimine (PEI) / Patti A. Longo, Jennifer M. Kavran, Min-Sung Kim, and Daniel J. Leahy -- Site-directed mutagenesis / Julia Bachman -- PCR-based random mutagenesis / Jessica S. Dymond -- Megaprimer method for mutagenesis of DNA / Craig W. Vander Kooi -- Troubleshooting PCR / Kirstie Canene-Adams -- Quantitative PCR / Jessica S. Dymond -- General PCR / Kirstie Canene-Adams -- Colony PCR / Megan Bergkessel and Christine Guthrie -- Chemical transformation of yeast / Megan Bergkessel and Christine Guthrie -- Transformation of E. coli via electroporation / Juliane C. Lessard -- Transformation of chemically competent E. coli / Rachel Green and Elizabeth J. Rogers.
  • 2013 ScienceDirect
    edited by Jon Lorsch.
    Computational prediction of RNA secondary structure -- Reverse-transcription PCR (RT-PCR) -- Northern blotting -- Explanatory chapter: nuclease protection assays -- In vitro transcription from plasmid or PCR-amplified DNA -- Measurement of in vivo synthesis rates -- Method for measuring mRNA decay rate in saccharomyces cerevisiae -- Analysis of polysomes from bacteria -- Polysome profile analysis - yeast -- Polysome analysis of mammalian cells -- Polysome analysis for determining mRNA and ribosome association in saccharomyces cerevisiae -- Oligo(dT)-primed RT-PCR isolation of polyadenylated RNA degradation intermediates -- Circularized RT-PCR (cRT-PCR): analysis of the 5' ends, 3' ends, and poly(A) tails of RNA -- RNA radiolabeling -- Fluorescently labeling synthetic RNAs -- Analysis of RNA by analytical polyacrylamide gel -- RNA purification by preparative polyacrylamide gel -- Explanatory chapter: nucleic acid concentration determination -- RNA purification-precipitation methods -- Reverse transcriptase dideoxy sequencing of RNA -- RNA structure experimental analysis-chemical modification -- Structural analysis of RNA backbone using in-line probing.
  • 2011 Springer Protocols
    edited by Graeme I. Murray.
    Laser capture microdissection : methods and applications / Kristen DeCarlo . [and others] -- Laser microdissection for gene expression profiling / Lori A. Field [and others] -- Gene expression using the PALM system / Jian-Xin Lu and Cheuk-Chun Szeto -- Immunoguided microdissection techniques / Michael A. Tangrea [and others] -- Optimized RNA extraction from non-deparaffinized laser-microdissected material / Danny Jonigk [and others] -- Laser capture microdissection for analysis of gene expression in formalin-fixed paraffin-embedded Tissue / Ru Jiang, Rona S. Scott, and Lindsey M. Hutt-Fletcher -- MicroRNA profiling using RNA from microdissected immunostained tissue / Clemens L. Bockmeyer [and others] -- Profiling solid tumor heterogeneity by LCM and biological MS of fresh-frozen tissue sections / Donald J. Johann [and others] -- Amplification testing in breast cancer by multiplex ligation-dependent probe amplification of microdissected tissue / Cathy B. Moelans, Roel A. de Weger, and Paul J. van Diest -- Detection and quantification of MicroRNAs in laser-microdissected formalin-fixed paraffin-embedded breast cancer tissues / Sarkawt M. Khoshnaw [and others] -- Laser capture microdissection applications in breast cancer proteomics / Rene B.H. Braakman [and others] -- Proteomic analysis of laser microdissected ovarian cancer tissue with SELDI-TOF MS / Isabelle Cadron [and others] -- LCM Assisted biomarker discovery from archival neoplastic gastrointestinal tissues / Patricia A. Meitner and Murray B. Resnick -- Purification of diseased cells from Barrett's esophagus and related lesions by laser capture microdissection / Masood A. Shammas and Manjula Y. Rao -- Laser microdissection of intestinal epithelial cells and downstream analysis / Benjamin Funke -- Application of laser microdissection and quantitative PCR to assess the response of esophageal cancer to neoadjuvant chemo-radiotherapy / Claus Hann von Weyhern and Bjorn L.D.M. Brucher -- Oligonucleotide microarray expression profiling of contrasting invasive phenotypes in colorectal cancer / Christopher C. Thorn, Deborah Williams, and Thomas C. Freeman -- Evaluation of gastrointestinal mtDNA depletion in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) / Carla Giordano and Giulia d'Amati -- Laser microdissection for gene expression study of hepatocellular carcinomas arising in cirrhotic and non-cirrhotic livers / Maria Tretiakova and John Hart -- Laser capture microdissection of pancreatic ductal adeno-carcinoma cells to analyze EzH2 by western blot analysis / Aamer M. Qazi [and others] -- Laser-capture microdissection of renal tubule cells and linear amplification of RNA for microarray profiling and real-time PCR / Susie-Jane Noppert, Susanne Eder, and Michael Rudnicki -- Subcellular renal proximal tubular mitochondrial toxicity with tenofovir treatment / James J. Kohler and Seyed H. Hosseini -- Application of laser-capture microdissection to study renal carcinogenesis / Kerstin Stemmer and Daniel R. Dietrich -- Laser-capture microdissection and transcriptional profiling in archival FFPE tissue in prostate cancer / Ajay Joseph and Vincent J. Gnanapragasam -- Quantitative analysis of the enzymes associated with 5-Fluorouracil metabolism in prostate cancer biopsies / Tomoaki Tanaka -- Microdissection of gonadal tissues for gene expression analyses / Anne Jørgensen, Marlene Danner Dalgaard, and Si Brask Sonne -- Duplex real-time PCR assay for quantifying mitochondrial DNA deletions in laser microdissected single spiral ganglion cells / Adam Markaryan, Erik G. Nelson, and Raul Hinojosa -- Neuronal type-specific gene expression profiling and laser-capture microdissection / Charmaine Y. Pietersen . [et al.] -- Region-specific in situ hybridization-guided laser-capture microdissection on postmortem human brain tissue coupled with gene expression quantification / Rene Bernard, Sharon Burke, and Ilan A. Kerman -- UV-laser microdissection and mRNA expression analysis of individual neurons from postmortem Parkinson's disease brains / Jan Grundemann, Falk Schlaudraff, and Birgit Liss -- Transcriptome profiling of murine spinal neurulation using laser capture microdissection and high-density oligonucleotide microarrays / Shoufeng Cao, Boon-Huat Bay, and George W. Yip -- Probing the CNS microvascular endothelium by immune-guided laser-capture microdissection coupled to quantitative RT-PCR / Nivetha Murugesan [and others] -- Laser-capture microdissection for factor VIII-expressing endothelial cells in cancer tissues / Tomoatsu Kaneko [and others] -- Laser-capture microdissection and analysis of liver endothelial cells from patients with Budd-Chiari syndrome / Selcuk Sozer and Ronald Hoffman -- Laser-capture microdissection of hyperlipidemic/ApoE-/- mouse aorta atherosclerosis / Michael Beer [and others] -- Gene expression profiling in laser-microdissected bone marrow megakaryocytes / Kais Hussein -- Specific RNA collection from the rat endolymphatic sac by laser-capture microdissection (LCM) : LCM of a very small organ surrounded by bony tissues / Kosuke Akiyama [and others] -- Use of laser capture microdissection on adult human articular cartilage for gene expression analysis / Naoshi Fukui, Yasuko Ikeda, and Nobuho Tanaka -- Laser-capture microdissection of developing barley seeds and cDNA array analysis of selected tissues / Johannes Thiel, Diana Weier, and Winfriede Weschke -- Quantitative RT-PCR gene expression analysis of a laser microdissected placenta : an approach to study preeclampsia / Yuditiya Purwosunu [and others].
  • 2009 Springer
    Raphael C. Wong, Harley Y. Tse, editors.
  • 2013 Springer
    Uri Gophna, editor.
    "Although the phenomenon of lateral gene transfer has been known since the 1940s, it was the genomics era that has really revealed the extent and many facets of this evolutionary/genetic phenomenon. Even in the early 2000s with but a handful of genomes available, it became clear that the nature of microorganisms is full of genetic exchange between lineages that are sometimes far apart. The years following this saw an explosion of genomic data, which shook the "tree of life" and also raised doubts about the most appropriate species concepts for prokaryotes. This book represents the manyfold contributions of LGT to the evolution of micro and, to an extent, macroorganisms by focusing on the areas where it has the largest impact: metabolic innovations and adaptations and speciation." Back cover.
  • 2003 Springer Protocols
    edited by Maurizio Federico.
    From lentiviruses to lentivirus vectors / M. Federico -- The choice of a suitable lentivirus vector: Transcriptional targeting / F. Lotti and F. Mavilio -- Choice and use of appropriate packaging cell types / A.L. Pacchia, S. Mukherjee and J.P. Dougherty -- Small- to large-scale production of lentivirus vectors / M.P. Marino, M.J. Luce and J. Reiser -- Detection and titration of lentivirus vector preparations / J. Gatlin, M. Islas-Ohlmayer and J.V. Garcia -- Detection and selection of lentiviral vector-transduced cells / Y. Cui and L.J. Chang -- Detection of replication-competent lentiviral particles / H. Segall and R.E. Sutton -- Lymphocytes / D. Chinnasamy and F. Candotti -- Monocyte/macrophages and dendritic cells / H. Segall and R.E. Sutton -- Hematopoietic stem and progenitor cells / R.E. Donahue and I.S. Chen -- Mesenchymal stem cells / X.Y. Zhang, V.F. La Russa and J. Reiser -- Hippocampal neurons / J.L. Nadeau -- Dorsal root ganglia sensory neurons / J. Fleming, S.L. Ginn and I.E. Alexander -- Cardiomyocytes / D. Bonci, M.V. Latronico and G. Condorelli -- Airway epithelia / L.G. Johnson, S.H. Randell and J.C. Olsen -- Corneal cells / B. Appukuttan, T. McFarland and J.T. Stout -- Retinal tissue / T. McFarland, B. Appukuttan and J.T. Stout -- Hiv-2 vectors / S.K. Arya, J.E. Cho and S.H. Chang -- Siv vectors / A. Ruggieri, D. Negre and F.L. Cosset -- Fiv vectors / N. Loewen [and others] -- Hybrid lentivirus vectors / V. Planelles -- Cells of respiratory epithelium / P.L. Sinn and P.B. McCray, Jr. -- Cells of the nervous system / C. Rosenblad and C. Lundberg.
  • ScienceDirect
    edited by Byron Rubin, Edward A. Dennis.
    Also available: Print – 1997
  • 2016 Springer
    Yuki Nakamura, Yonghua Li-Beisson editors.
    Lipids: from chemical structures, biosynthesis, and analyses to industrial applications -- Roles of lipids in photosynthesis -- DGDG and glycolipids in plants and algae -- Thylakoid development and galactolipid synthesis cyanobacteria -- Role of lipids in chloroplast biogenesis -- Role of MGDG and non-bilayer lipid phases in the structure and dynamics of chloroplast thylakoid membranes -- Chemical genetics in dissecting membrane glycerolipid functions -- Triacylglycerol accumulation in photosynthetic cells in plants and algae -- Cellular organization of triacylglycerol biosynthesis in microalgae -- High-throughput genetics strategies for identifying new components of lipid metabolism in the green alga Chlamydomonas reinhardtii -- Plant sphingolipid meatbolism and function -- Plant surface lipids and epidermis development -- Role of lipid metabolism in plant pollen exine development -- Long-distance lipid signaling and its role in plant development and stress response -- Acyl-CoA-biinding proteins (ACBPs) in plant development -- The rise and fall of Jasmonate biological activities -- Green leaf volatiles in plant signaling and response -- Omics in Chlamydomonas for biofuel production -- Microalgae as a source for VLC-PUFA production -- Understanding sugar catabolism in unicellular cyanobacteria toward the application in biofuel and biomaterial production.
  • 2005 Springer
    edited by Anne Kathrine Hvoslef-Eide and Walter Preil.
  • 2010
    Katherine Lin Tsai.
    Lab-on-a-Chip devices are attractive for medical diagnostics due to their ability to perform laboratory tasks on small scales. This manuscript explores magnetic nanoparticle-based technologies for low-power, remote actuation in Lab-on-a-Chip systems. Two specific applications -- microfluidic pumping and cell separation -- are investigated. First, chemistry-independent microfluidic pumping using magnetic nanoparticles suspended within a fluid has been demonstrated. Magnetic circuits to generate magnetic field gradients for actuating superparamagnetic nanoparticles in fluids have been fabricated, and changes in fluid velocities when the magnetic circuits are applied have been measured. Results show that the fluid velocity in a microchannel increases 30 [mu]m/sec when a magnetic field gradient of ~3 T/m is applied, and 10 -- 70 [mu]m/sec when a magnetic field gradient of ~5 T/m is applied. The magnetic, optical, and mechanical properties of a magnetic polymer that is composed of SU-8 polymer embedded with nickel nanoparticles (SU8-Ni) have also been characterized. Results show the SU8-Ni composites exhibit weak ferromagnetic behavior and saturate at magnetic fields around 0.2 T, the transmittance of light through SU8-Ni decreases with increasing Ni concentrations, and SU8-Ni has a Young's modulus that is 30 times lower and a hardness that is 1400 times lower than that of bulk Ni. A torsional microactuator made of SU8-Ni has been fabricated to demonstrate its use for magnetic actuation, and a model of the SU8-Ni based on deflection experiments of the actuator has been developed. Micropillars made of SU8-Ni have been fabricated for capturing and concentrating breast cancer cells in microchannels. Magnetic field gradients up to 10,000 T/m have been predicted for an SU8-Ni pillar that is 100 [mu]m tall, 100 [mu]m in diameter, and composed of 12.5% Ni by weight. Experimental results show the SU8-Ni micropillars capture magnetic bead-bound cells when an external magnet is applied and release the cells when the magnet is removed.
  • 2013 Cambridge
    [edited by] Jan de Boer, Clemens A. van Blitterswijk.
    "This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student, or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research"--Provided by publisher.
  • 2007 CRCnetBASE
    edited by Fereidoon Shahidi.
    pt. 1. Marine by-products characterisation, recovery and processing: 1. Physical and chemical properties of protein seafood by-products / T. Rustad ; 2. Physical and chemical properties of lipid by-products from seafood waste / J.P. Kerry and S.C. Murphy ; 3. On-board handling of marine by-products to prevent microbial spoilage, enzymatic reactions and lipid oxidation / E. Falch, M. Sandbakk and M. Aursand ; 4. Recovery of by-products from seafood processing streams / J.A. Torres ... [et al.] ; 5. Increasing processed flesh yield by recovery from marine by-products / K.D.A. Taylor and A. Himonides ; 6. Enzymatic methods for marine by-products recovery / F. Guerard ; 7. Chemical processing methods for protein recovery from marine by-products and underutilized fish species / H.G. Kristinsson, A.E. Theodore and B. Ingadottir -- pt. 2. Food uses of marine by-products: 8. By-catch, underutilized species and underutilized fish parts as food ingredients / I. Batista ; 9. Mince from seafood processing by-product and surimi as food ingredients / J.-S. Kim and J.W. Park ; 10. Aquatic food protein hydrolysates / H.G. Kristinsson ; 11. Engineering and functional properties of powders from underutilized marine fish and seafood products / S. Sathivel and P.J. Bechtel ; 12. Marine oils from seafood waste / F. Shahidi ; 13. Collagen an gelatin from marine by-products / J.M. Regenstein and P. Zhou ; 14. Seafood flavor from processing by-products / C.M. Lee ; 15. Fish and bone as a calcium source / S.-K. Kim and W.-K. Jung ; 16. Chitin and chitosan from marine by-products / F. Shahidi ; 17. Marine enzymes from seafood by-products / M.T. Morrissey and T. Okada ; 18. Antioxidants from marine by-products / F. Shahidi and Y. Zhong ; 19. Pigments from by-products of seafood processing / B.K. Simpson -- pt. 3. Non-food uses of marine by-products: 20. By-products from seafood processing for aquaculture and animals feeds / P.J. Bechtel ; 21. Using marine by-products in pharmaceutical, medical and cosmetic products / J. Losso ; 22. Bio-diesel and bio-gas production from seafood processing by-products / R. Zhang and H.M. El-Mashad ; 23. Composting of seafood wastes / A.M. Martin.
  • 2013 CRCnetBASE
    Qing-Hua Qin.
    Introduction to bone materials -- Basic bone remodeling theory -- Multifield internal bone remodeling -- Multifield surface bone remodeling -- Theoretical models of bone modeling and remodeling -- Effect of parathyroid hormone on bone metabolism -- Cortical bone remodeling under mechanical stimulus -- Bone remodelling under pulsed electromagnetic fields and clinical applications -- Experiments.
  • 2005 Springer
    2005 Springer Protocols
    edited by John M. Walker and Ralph Rapley.
    Basic techniques in molecular biology / Ralph Rapley -- Probe design, production, and applications / Marilena Aquino de Muro -- Restriction enzymes: tools in clinical research / Gareth J.S. Jenkins -- Southern blotting as a diagnostic method / Bronwen Harvey and Pirkko Soundy -- Western blotting as a diagnostic method / Pirkko Soundy and Bronwen Harvey -- Principles and medical applications of the polymerase chain reaction / Bimal D. M. Theophilus -- Single strand conformation polymorphism (SSCP) analysis / Igor Vorechovsky -- Denaturing gradient gel electrophoresis (DGGE) / Jeroen H. Roelfsema and Dorien J.M. Peters -- Quantitative analysis of DNA sequences by PCR and solid phase sequencing / Anu Suomalainen and Ann-Christine Syvänen -- Introduction to capillary electrophoresis of DNA: biomedical applications / Beatriz Sanchez-Vega -- Mapping techniques / Simon G. Gregory -- Dideoxyfingerprinting for mutation detection / Ioannis Bossis, Antonios Voutetakis, and Constantine A. Stratakis -- Conformation sensitive gel electrophoresis / Marian Hill -- Amplification refractory mutation system and molecular diagnostics / Richard Kitching and Arun Seth -- Ligase chain reaction / Carla Osiowy -- Chemical cleavage of mismatch: theory and clinical applications / Neil V. Whittock and Louise Izatt -- The protein truncation test / Johan T. den Dunnen -- Linkage, allele sharing, and association / Mara Giordano -- Single nucleotide polymorphisms: technology and applications / Cyril Mamotte, Frank Christiansen, and Lyle J. Palmer -- cDNA microarrays / Philip G. Febbo -- Nucleic acid sequence-based amplification / Katherine Loens, D. Ursi, H. Goosens, and M. Ieven -- The oligonucleotide ligation assay / Faye A. Eggerding -- Quantitative taqman real-time PCR: diagnostic and scientific applications / Jörg Dötsch, Ellen Schoof, and Wolfgang Rascher -- Use of denaturing high-performance liquid chromatography in molecular medicine / Elizabeth L. Rugg and Gareth J. Magee -- Quantitative PCR / David Sugden -- Liquid chromatography-mass spectrometry of nucleic acids / Herbert Oberacher and Walther Parson -- Comparative genomic hybridization in clinical and medical research / Peng-Hui Wang, Yann-Jang Chen, and Chi-Hung Lin -- Bioinformatics tools for gene and protein sequence analysis / Bernd H.A. Rehm and Frank Reinecke -- In situ hybridization / Amanda D. Watters -- Enzyme-linked immunosorbent assay / William J. Jordan -- Protein therapeutics: mouse, humanized, and human antibodies / Benny K.C. Lo -- Karyotyping / Avery A. Sandberg, John F. Stone, and Zhong Chen -- Microsatellite analysis / Rachel E. Ibbotson and Anton E. Parker -- Analysis of chromosomal translocations / Andreas Hochhaus -- Differential display: theory and applications / Irina Gromova, Pavel Gromov, and Julio E. Celis -- Techniques for gene expression profiling / Mark P. Richards -- Capillary electrophoresis in clinical analysis / Margaret A. Jenkins and Sujiva Ratnaike -- Flow cytometry in the biomedical arena / James L. Weaver and Maryalice Stetler-Stevenson -- Immunocytochemistry / Patricia A. Fetsch -- Ribotyping in clinical microbiology / Patricia Severino and Sylvain Brisse -- Diagnostic applications of protein microarrays / Samir Hanash -- The human genome project / Rahul Chodhari and Eddie Chung -- Prenatal diagnosis of inborn errors of metabolism / Guy T.N. Besley -- Gene therapy: methods and application / Stella B. Somiari.
  • 2008 Springer
    Bert Gordijn, Ruth Chadwick, editors.
  • 2013 Springer
    Peiman Hematti, Armand Keating, editors.
    1. Mesenchymal stromal cells in regressive medicine: a perspective / Peiman Hematti and Armand Keating -- 2. MSCs: changing hypotheses, paradigms, and controversies on mechanisms of action in repairing tissues / Darwin J. Prockop and Roxanne L. Reger -- 3. MSCs: the need to rethink / Paolo Bianco and Pamela G. Robey -- 4. Characterization of MSCs: from early studies to the present / Mark F. Pittenger -- 5. MSCs as therapeutics / Arnold I. Caplan -- 6. MSC niche for hematopoiesis / Daniel Lucas, Sandra Pinhol and Paul S. Frenette -- 7. Immunomodulatory properties of MSCs / Maria Ester Bernardo, Lynne M. Ball, Franco Locatelli and Willem E. Fibbe -- 8. MSCs and inmate immune responses: a balancing act / Krisztián Németh and Éva Mezey -- 9. MSCs: paracrine effects / Siddiraju V. Boregowda and Donald G. Phinney -- 10. Cross-talk between MSCs and their environments / Thomas P. Lozito and Rocky S. Tuan -- 11. Human MSCs from bone marrow, umbilical cord blood, and adipose tissue: all the same? / Patrick Wuchter and Anthony D. Ho -- 12. MSCs in solid tumors and hematological malignancies: from basic biology to therapeutic applications / Rodrigo Jaeamo, Erika Spaeth, Venkata Battula, Frank Marini and Michael Andreeff -- 13. MSC studies in large-animal models / Bruce A. Bunnell, Christine Gagliardi, and Maria Isabel Ribeiro Dias -- 14. Defining the potential of MSCs with a prenatal large animal model / Grac̦a Almeida-Porada, Christopher D. Orada and Esmail D. Zanjani -- 15. Bench-to-bedside development of MSC therapies: a multidisciplinary approach / Sowmya Viswanathan and Elizabeth J. Read -- 16. cGMP production of MSCs / Derek J. Hei and David H. McKenna, Jr. -- 17. MSCs: the US regulatory perspective / Adrian P. Gee -- 18. MSCs: clinical applications and European regulatory aspects / Jens Reinhardt, Egbert Flory, Isabel Büttel, Christa Schröder, Stefan Fricke, Vladan Vucinic, Michael Cross and Dietger Niederwieser -- 19. Stem cell treatments around the World: boon or bane?/ Alok Srivastava -- 20. Safety issues in MSC therapy / Minoo Battiwalla and A. John Barrett -- 21. In vivo imaging of MSCs / Jeff W.M. Bulte -- 22. National Heart, Lung and Blood Institute support of cellular therapies regenerative medicine / Traci Heath Mondoro and John Thomas -- 23. MSC therapy of inborn errors / Edwin M. Horwitz -- 24. MSCs for enhancement of hematopoietic progenitor cell engraftment and poor graft function / Paolo F. Caimi and Hillard M. Lazarus -- 25. MSCs ro graft-versus-host disease / Jakub Tolar, Katarina Le Blanc and Bruce R. Blazar -- 26. MSCs in pediatric hematopoietic stem cell transplantation / Lynne M. Ball, Maria Ester Bernardo, Franco Locatelli and R. Maarten Egeler -- 27. MSC for ex vivo expansion of umbilical cord blood cells / Ian K. McNiece, Simon N. Robinson, and Elizabeth J. Shpall -- 28. MSCs for autoimmune diseases / Alan Tyndall and Chiara Bocelli -- 29. MSCs for induction of solid organ allograft acceptance / Marc Dahlke, Philipp Renner and Elke Eggenhofer -- 30. MSCc for gastrointestinal disorders / Maria Ester Bernardo, Angela Maria Cometa and Franco Locatelli -- 31. MSCs for cardiac repair / Amish N. Raval and Timothy A. Hacker -- 32. MSCs for treatment of acute lung injury / Vladimir B. Serikov, Anna Krasnodembskaya, Jae Wood Lee, Marlowe W. Eldridge and Michael A. Matthay -- 33. MSCs for diabetes / Luca Inverardi, Giacomo Lanzoni, Juan Dominguez-Bendala and Camillo Ricordi -- 34. MSCs for renal repair / Anna M. Gooch and Christof Westenfelder -- 35. MSCs for the treatment of stroke, spinal cord injury, and traumatic brain injury: from bench work to clinical trials / Bing Yang, Ramy El Khoury, and Sean I. Savitz -- 36. MSCs in reconstructive surgery / Summer E. Hanson and Michael L. Bentz -- 37. MSCs in orthopedic surgery / Summer E. Hanson and Nicholas H. Maassen -- 30. Adipose tissue-derived MSCs: moving to the clinic / Pedro P. Carvalho, Manuela E. Gomes, Rui L. Reis and Jeffrey M. Gimble.
  • v. 1-2, 2010. CRCnetBASE
    v. 2 CRCnetBASE
    edited by Christina D. Smolke.
    [v. 1.] Fundamentals -- [v. 2.] Tools and applications.
  • 2011 Springer Protocols
    edited by Joakim Dillner.
    Genetic research and biobanks / D. Chalmers -- The need to downregulate: A minimal ethical framework for biobank research / M.G. Hansson -- Nordic biological specimen bank cohorts as basis for studies of cancer causes and control: Quality control tools for study cohorts with more than two million sample donors and 130,000 prospective cancers / E. Pukkala -- Biobanks collected for routine healthcare purposes: Build-up and use for epidemiologic research / J. Dillner and K. Andersson -- Biobanks and registers in epidemiologic research on cancer / E. Pukkala -- Study designs for biobank-based epidemiologic research on chronic diseases / E. Laara -- The European prospective investigation into cancer and nutrition biobank / P. Hainaut ... [et al.] -- The aids and cancer specimen resource / L.W. Ayers ... [et al.] -- Specific advantages of twin registries and biobanks / J. Kaprio -- The Swedish multi-generation register / A. Ekbom -- Multigenerational information: The example of the Icelandic genealogy database / H. Tulinius -- Creation of a new prospective research biobank: The example of HUNT3 / K. Hveem -- Best practices for establishing a biobank / G. Hallmans and J.B. Vaught -- Extraction, quantitation, and evaluation of function DNA from various sample types / M. Ivarsson and J. Carlson -- Cervical cytology biobanks as a resource for molecular epidemiology / M. Arbyn ... [et al.] -- Biobanking of fresh frozen tissue from clinical surgical specimens: Transport logistics, sample selection, and histologic characterization / J. Botling and P. Micke -- Protein extraction from solid tissue / C. Ericsson and M. Nister -- Collection and preservation of frozen microorganisms / R. Tedeschi and P. De Paoli -- Handling of solid brain tumor tissue for protein analysis / C. Ericsson and M. Nister -- Blood plasma handling for protein analysis / C. Ericsson and M. Nister -- Biobank informatics: Connecting genotypes and phenotypes / J.E. Litton -- A practical guide to constructing and using tissue microarrays / I. Chandler, R. Houlston and G. Landberg -- Breast cancer genomics based on biobanks / A. Forsti and K. Hemminki -- Monitoring, alarm, and data visualization service on sample preparing and sample storing devices in biobanks / H. Hauksdottir, K. Jonsdottir and A. Thorarinsson -- Fresh frozen tissue: RNA extraction and quality control / J. Botling and P. Micke.
  • v. 1-, 1997- Springer Protocols
    Walker, John M.
  • 2013 ScienceDirect
    edited by Amy E. Keating.
    Computational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides.
  • NCBI Bookshelf
    This searchable database is a collection of in vivo molecular imaging agents developed for positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), ultrasound (US), computed tomography (CT), and optical imaging. MICAD, a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, is being developed by NCBI, the National Center for Biotechnology Information".
  • 2013 Wiley
    edited by Murugan Ramalingam, Esmaiel Jabbari, Seeram Ramakrishna, and Ali Khadembosseini.
    Stem cells and nanotechnology in tissue engineering and regenerative medicine / Rocky Tuan -- Nanofiber technology for controlling stem cell functions and tissue engineering / Seeram Ramakrishna, Shayanti Mukherjee -- Micro- and nanoengineering approaches to developing gradient biomaterials suitable for interface tissue engineering / Ali Khademhosseini, Serge Ostrovidov -- Microengineered polymer and ceramic-based biomaterial scaffolds : a topical review on design, processing, and biocompatibility properties / Bikramjit Basu, Garima Tripathi -- Synthetic enroutes to engineer electrospun scaffolds for stem cells and tissue regeneration / Seeram Ramakrishna, Radhakrishnan Sridhar -- Integrating top-down and bottom-up scaffolding tissue engineering approach for bone regeneration / Esmaiel Jabbari, Yunzhi Yang -- Characterization of the adhesive interactions between cells and biomaterials / John Fisher -- Microfluidic formation of cell-laden hydrogel modules for tissue engineering / Shoji Takeuchi, Yuya Morimoto -- Micro- and nanospheres for tissue engineering / John Jansen -- Micro and nano technologies to engineer bone regeneration / Balaji Sitharaman -- Micro and nanotechnology for vascular tissue engineering / Laura Suggs -- Application of stem cells in ischemic heart disease / Gangapatnam Subrahmanyam, Ravi Shankar.
  • 2010 CRCnetBASE
    Karl Fraser, Zidong Wang, Xiaohui Liu.
  • 2014 CRCnetBASE
    edited by Luis Rueda.
    Microarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of microarrays, the book:Describes the key stages of image processing, gridding, segmentation, compression, quantification, and normalizationFeatures cutting-edge approaches to clustering, biclustering, and the reconstruction of regulatory networksCovers different ty.
  • 2005 Springer
    U.R. Müller, D.V. Nicolau (eds.).
    pt. 1. General microarray technologies -- pt. 2. DNA microarrays -- pt. 3. Protein microarrays -- pt. 4. Cell & tissue microarrays.
  • 2008 Springer
    Andreas Bosio, Bernhard Gerstmayer, editors.
    Also available: Print – 2008
  • 2012 Wiley
    Prakash S. Bisen, Mousumi Debnath, Godavarthi B.K.S. Prasad.
  • 2012 Springer Protocols
    edited by José-Luis Barredo.
  • 2003 CRCnetBASE
    Eric R. Lee.
  • 2012
    Angela Ruohao Wu.
    Protein--DNA interactions are responsible for numerous critical cellular events: for example, gene expression and silencing are mediated by transcription factor protein binding and histone protein modifications, and DNA replication and repair rely on site specific protein binding. Chromatin immunoprecipitation (ChIP) is the only molecular assay that directly determines, in a living cell, the binding association between a protein of interest and specific genomic loci. It is an indispensible tool in the biologists' toolbox, but the many limitations of this technique prevent broad adoption of ChIP in biological studies. The typical ChIP assay can take up to one week to complete, and the process is technically tricky, yet tedious. ChIP assay yields are also low, thus requiring on the order of millions to billions of cells as starting material, which makes the assay unfeasible for studies on rare or precious samples. Cancer stem cells (CSCs), for instance, are obtained from primary tumors, and FACS sorting of the dissociated tumor cells rarely yields more than ~100,000 CSCs per tumor. This thesis describes the microfluidics-based strategies for performing ChIP. The first design for a microfluidic ChIP design utilizes the automation and scalability aspects of microfluidics to reduce both total and hands-on assay time, and improve throughput. It can take chromatin prepared using any existing ChIP protocol as input, and generate ChIP-qPCR results in just 1 day. The device is shown to be comparable to existing ChIP protocols, and can detect cellular epigenetic changes induced by external cytokine stimulants. It was used to investigate transcription factor binding dynamics in an aging-related pathway, and was able to link transcription factor binding to local changes in histone modifications. The second design of the microfluidic ChIP platform focuses on addressing the cell number requirements of ChIP. In addition to reducing assay time through automation, this design incorporates microfluidic designs that allow whole fixed cells as input, and enables automated ChIP from as few as 2,000 cells. Finally, using this high-sensitivity ChIP device in conjunction with next-generation sequencing technology, a protocol for determining genome-wide epigenetic landscapes from as few as 2,000 cells is developed, with the ultimate goal of performing protein-DNA association studies on CSCs.
  • 2013 Springer Protocols
    edited by Gareth Jenkins, Colin D. Mansfield.
    Present technology and future trends in point-of-care microfluidic diagnostics / Lawrence Kulinsky, Zahra Noroozi, and Marc Madou -- Teaching microfluidic diagnostics using Jell-O® chips / Cheng Wei T. Yang and Eric T. Lagally -- Fundamentals of microfluidics for high school students with no prior knowledge of fluid mechanics / Vishal Tandon and Walter Peck -- Measuring microchannel electroosmotic mobility and zeta potential by the current monitoring method / Chenren Shao and Don L. DeVoe -- Overview of the microfluidic diagnostics commercial landscape / Lily Kim -- Practical aspects of the preparation and filing of patent applications / Fiona Bessoth -- Introduction to in vitro diagnostic device regulatory requirements / Jonathan Day -- Microfluidic device fabrication by thermoplastic hot-embossing / Shuang Yang and Don L. DeVoe -- Introduction to glass microstructuring techniques / Radoslaw Mazurczyk and Colin D. Mansfield -- Glass microstructure capping and bonding techniques / Radoslaw Mazurczyk, Colin D. Mansfield, and Marcin Lygan -- Rapid prototyping of PDMS devices using SU-8 lithography / Gareth Jenkins -- Microfluidic interface technology based on stereolithography for glass-based lab-on-a-chips / Song-I Han and Ki-Ho Han -- Three-dimensional, paper-based microfluidic devices containing internal timers for running time-based diagnostic assays / Scott T. Phillips and Nicole K. Thom -- Thread based devices for low-cost diagnostics / Meital Reches -- Droplet-based microfluidics / Sanjiv Sharma [and others] -- Droplet-based microfluidics for binding assays and kinetics based on FRET / Monpichar Srisa-Art and Sanjiv Sharma -- Surface treatments for microfluidic biocompatibility / N.J. Shirtcliffe, R. Toon, and P. Roach -- Superhydrophobicity for antifouling microfluidic surfaces / N.J. Shirtcliffe and P. Roach -- Application of microfluidic devices for viral diagnosis in developing countries / Samantha M. Hattersley, John Greenman, and Stephen J. Haswell -- Applications of microfluidics for molecular diagnostics / Harikrishnan Jayamohan, Himanshu J. Sant, and Bruce K. Gale -- Quantitative heterogeneous immunoassays in protein modified polydimethylsiloxane microfluidic channels for rapid detection of disease biomarkers / Peng Li -- Breast cancer diagnostics using microfluidic multiplexed immunohistochemistry / Minseok S. Kim, Seyong Kwon, and Je-Kyun Park -- Charged-coupled device (CCD) detectors for lab-on-a chip (LOC) optical analysis / Avraham Rasooly, Yordan Kostov, and Hugh A. Bruck -- Multilayer microfluidic poly(ethylene glycol) diacrylate hydrogels / Michael P. Cuchiara and Jennifer L. West -- Purification of DNA/RNA in a microfluidic device / Andy Fan, Samantha Byrnes, and Catherine Klapperich -- Agarose droplet microfluidics for highly parallel and efficient single molecule emulsion PCR / Xuefei Leng and Chaoyong James Yang -- Integrated fluidic circuits (IFCs) for digital PCR / Ramesh Ramakrishnan [and others] -- microFIND® approach to fluorescent in situ hybridization (FISH) / Andrea Zanardi, Emanuele Barborini, and Roberta Carbone -- ELISA lab-on-a-chip (ELISA-LOC) / Avraham Rasooly, Hugh A. Bruck, and Yordan Kostov -- Multiplexed surface plasmon resonance imaging for protein biomarker analysis / Eric Ouellet, Louise Lund, and Eric T. Lagally -- Surface acoustic wave (SAW) biosensors : coupling of sensing layers and measurement / Kerstin Lange, Friederike J. Gruhl, and Michael Rapp -- Microchip UV absorbance detection applied to isoelectric focusing of proteins / Junjie Ou and Carolyn L. Ren.
  • 2006 CRCnetBASE
    Paul C.H. Li.
  • 2009 Springer Protocols
    edited by David J. Carroll.
    Expression of exogenous mRNA in Xenopus laevis embryos for the study of cell cycle regulation / Jill C. Sible and Brian N. Wroble -- Use of luciferase chimaera to monitor PLC[zeta] expression in mouse eggs / Karl Swann ... [et al.] -- Analysis of 14-3-3 family member function in Xenopus embryos by microinjection of antisense morpholino oligos / Jeffrey M.S. Lau and Anthony J. Muslin -- A microinjectable biological system, the Xenopus oocyte, as an approach to understanding signal transduction protein function / Katia Cailliau and Edith Browaeys-Poly -- Combining microinjection and immunoblotting to analyse MAP kinase phosphorylation in single starfish oocytes and eggs / David J. Carroll and Wei Hua -- Analysis of signaling pathways in zebrafish development by microinjection / William H. Kinsey -- Protein inhibition by microinjection and RNA-mediated interference in tissue culture cells : complementary approaches to study protein function / Jane R. Stout, Rania S. Rizk, and Claire E. Walczak -- DNA delivery by microinjection for the generation of recombinant mammalian cell lines / Sebastien Chenuet ... [et al.] -- Bacteriophage [phi]C31 integrase mediated transgenesis in Xenopus laevis for protein expression at endogenous levels / Bryan G. Allen and Daniel L. Weeks -- Germline transformation of Caenorhabditis elegans by injection / Pavan Kadandale, Indrani Chatterjee, and Andrew Singson -- Quantitative microinjection of mouse oocytes and eggs / Douglas Kline -- Microinjection of follicle-enclosed mouse oocytes / Laurinda A. Jaffe ... [et al.] -- Functional studies of regulatory genes in the sea urchin embryo / Vincenzo Cavalieri, Maria Di Bernardo, and Giovanni Spinelli -- Exploring the cytoskeleton during intracytoplasmic sperm injection in humans / Vanesa Y. Rawe and Héctor Chemes -- Somatic cell nuclear transfer in the mouse / Satoshi Kishigami and Teruhiko Wakayama.
  • 2012 Springer
    Niall Barron, editor.
    "MicroRNAs are small, non-coding RNA molecules that interact with target mRNAs to modulate their translation. They are now recognized as widespread and critical regulators of gene expression in the cell. This book is aimed at both industry- and academic-based researchers in the Biopharmaceutical production space who wish to learn more about these fascinating molecules..."--Page [4] of cover.
  • 2003 Wiley
    Michael Hoppert.
    ch. 1. Light Microscopy, p. 1-145 -- ch. 2. Electron Microscopy, p. 147-286 -- ch. 3. Other Microscopical Methods and their Application Potential, p. 287-319.
  • 2013 CRCnetBASE
    Guanghui Ma, Zhiguo Su.
    1. Microspheres for enzyme immobilization / Fei Gao, Yuxia Wang, and Guanghui Ma -- 2. Microspheres for cell culture / Weiqing Zhou, Guanghui Ma, and Zhiguo Su -- 3. Microcapsules for cell transplantation : design, preparation, and application / Guojun Lv, Ying Zhang, Mingqian Tan, Hongguo Xie, and Xiaojun Ma -- 4. Microspheres for the separation and refolding of proteins with an emphasis on particles made of agarose / Jan-Christer Janson -- 5. Microspheres for separation of bioactive small molecules / Fangling Gong, Guifeng Zhang, and Zhiguo Su -- 6. Microspheres for separation of PEG-modified biomolecules / Yongdong Huang, Yanqin Zhai, and Zhiguo Su -- 7. Microspheres for solid-phase organic synthesis / Jing Zhang and Zhiguo Su -- 8. Microspheres for solid-phase modification of proteins / Tao Hu and Zhiguo Su -- 9. Microspheres and microcapsules for protein drug delivery / Lianyan Wang, Tingyuan Yang, and Guanghui Ma -- 10. Micro/nanospheres for gene drug delivery / Jie Wu and Guanghui Ma -- 11. Microspheres for targeting delivery of anticancer drugs / Wei Wei, Zhanguo Yue, Hua Yue, and Guanghui Ma -- 12. Microspheres for targeting delivery to brain / Chen Jiang, Xinguo Jiang, Yang Liu, Kun Shao, and Rongqin Huang -- 13. Nano/microspheres in bioimaging and medical diagnosis / Xiaohui Li and Chunying Chen -- 14. Affinity nanoparticles for detection / Haruma Kawaguchi and Hiroshi Handa.
  • 2010
    Kunal Kumar Ghosh.
    Fluorescence microscopy has emerged as a workhorse of modern biology and medicine. Fluorescence microscopes are indispensable as tools for basic research in the biological sciences, enable platforms for drug discovery in the biotechnology and pharmaceutical industries, and are increasingly aiding in several clinical diagnostic applications. However, state-of-the-art fluorescence microscopes remain bulky and expensive benchtop instruments with an architecture that impedes usage in certain applications and a cost that precludes adoption in large numbers. For example existing benchtop fluorescence microscopes are not amenable for in vivo imaging in animals, with the mouse being a common animal subject, especially during awake, active behavior. For the field of neuroscience in particular, such an experimental capability permits correlating causal cellular processes with animal behavior -- a longstanding goal. Inspired by this need, we have designed a miniature fluorescence microscope that can be borne by a mouse during active behavior. We have fabricated several such microscopes, each less than 2 g in mass, perhaps heralding a transformation in fluorescence microscopy from today's bulky and expensive benchtop paradigm towards miniature and mass-producible devices. Our fabricated microscopes achieve 2.5 μm spatial resolution imaging fields-of-view up to 800 μm x 600 μm at 36 Hz, suitable for cellular-level imaging at high temporal resolution. To facilitate design of our microscopes, we have adopted a modeling-based microscope design methodology, akin to that used in the design of integrated circuits, and have developed a set of tools to model the microscope as an integrated device from the specimen to final digital image. We have experimentally validated fabricated microscopes for in vivo brain imaging in freely behaving mice, specifically using them for: 1) Imaging cerebellar vasculature and hemodynamics during activity; and 2) Imaging cerebellar Purkinje cell Calcium dynamics, analyzing spiking activity of populations of neurons with single neuron specificity during different motor behaviors. We also show how several of these microscopes imaging in parallel can enable new high-throughput imaging solutions with the potential to achieve broad impact, specifically demonstrating high-throughput image-based assays for: 1) Mutant phenotype screening in genetic model species such as the zebrafish; and 2) Multiple well plate cell analyses. Finally, we use a Bayesian iterative image restoration algorithm to enhance acquired microscope images, and show how spatial resolution can be further scaled into the sub-micron regime by leveraging advances in digital image sensing technology in conjunction with our post-acquisition image restoration algorithm.
  • 2013 Springer
    Norma Allewell, Linda O. Narhi, Ivan Rayment (eds.).
    This volume of the series Biophysics for the Life Sciences focuses on the conceptual framework and major research tools of contemporary molecular biophysics. It is designed to enable non-specialists -both students and professionals in other fields - to understand how these approaches can be used across the biosciences and in medicine, agriculture, biotechnology, pharmaceutical development and other fields. The scope of this volume is appropriate for advanced undergraduate and graduate courses in biophysics and biophysical chemistry. The book begins with an overview of the development of molecular biophysics and a brief survey of structural, physical, and chemical principles. Subsequent chapters written by experts present, with examples, the major experimental methods: optical spectroscopy, X-ray and neutron diffraction and scattering, nuclear magnetic resonance, electron paramagnetic resonance, mass spectrometry, and single molecule methods. The relationship between the biophysical properties of biological macromolecules and their roles as molecular machines is emphasized throughout and illustrated with three examples DNA helicases, rotary motor ATPases, and myosin.The concluding chapter discusses future prospects in X-ray and neutron scattering, mass spectrometry, and pharmaceutical development.
  • 2010 ScienceDirect
    [edited by] Wayne W. Grody ... [et al.].
    Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. This handbook provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.
  • 2010 ScienceDirect
    edited by George P. Patrinos, Wilhelm J. Ansorge.
    Chapter 1. Molecular Diagnostics: Past, Present, and Future / George P. Patrinos, Wilhelm J. Ansorge -- Chapter 2 . Allele-Specific Mutation Detection / Aglaia Athanassiadou, Eleana F. Stavrou, Adamandia Papachatzopoulou, George P. Patrinos -- Chapter 3. Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation / Chinh T. Bui, Emmanuelle Nicolas, Georgina Sallmann, Maria Chiotis, Andreana Lambrinakos, Kylee Rees, Ian Trounce, Richard G.H. Cotton, Lauryn Blakesley, Andrew K. Godwin, Anthony T. Yeung -- Chapter 4. Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis / Panayiotis G. Menounos, George P. Patrinos -- Chapter 5. Capillary Electrophoresis / Anja Bosserhoff, Claus Hellerbrand -- Chapter 6. Temperature and Denaturing Gradient Gel Electrophoresis / Hartmut Peters, Peter N. Robinson -- Chapter 7. Real-Time Polymerase Chain Reaction / Lut Overbergh, Anna-Paula Giulietti, Dirk Valckx, Chantal Mathieu -- Chapter 8 - Pyrosequencing / Sharon Marsh -- Chapter 9. Application of Padlock and Selector Probes in Molecular Medicine / Mats Nilsson, Chatarina Larsson, Johan Stenberg, Jenny Göransson, Ida Grundberg, Magnus Isaksson, Tim Conze, Sara Henriksson -- Chapter 10. Molecular Cytogenetics in Molecular Diagnostics / Holger Tönnies -- Chapter 11. Analysis of Human Splicing Defects Using Hybrid Minigenes / Franco Pagani, Francisco E. Baralle -- Chapter 12. Detection of Genomic Duplications and Deletions / Graham R. Taylor, Carol A. Delaney -- Chapter 13. Multiplex Ligation-Dependent Probe Amplification (MLPA) and Methylation-Specific (MS)-MLPA: Multiplex Detection of DNA/mRNA Copy Number and Methylation Changes / Eline M. Sepers, Jan P. Schouten -- Chapter 14. Molecular Techniques for DNA Methylation Studies / Jörg Tost, Ivo G. Gut -- Chapter 15. High-Resolution Melting Curve Analysis for Molecular Diagnostics / Jared S. Farrar, Gudrun H. Reed, Carl T. Wittwer -- Chapter 16. DNA Microarrays and Genetic Testing / Lars Dyrskjøt, Karina Dalsgaard-Sørensen, Marie Stampe-Ostenfeld, Karin Birkenkamp-Demtroder, Kasper Thorsen, Claus L. Andersen, Mogens Kruhøffer, Jens L. Jensen, Torben F. Ørntoft -- Chapter 17. Arrayed Primer Extension Microarrays for Molecular Diagnostics / Neeme Tonisson, Eneli Oitmaa, Kaarel Krjutskov, Janne Pullat, Ilona Lind, Merike Leego, Ants Kurg, Andres Metspalu -- Chapter 18. Application of Proteomics to Disease Diagnostics / Samir Hanash, Ji Qiu, Vitor Faca -- Chapter 19. RNA-Based Variant Detection: The Protein Truncation Test / Johan T. den Dunnen -- Chapter 20. Protein Diagnostics by Proximity Ligation: Combining Multiple Recognition and DNA Amplification for Improved Protein Analyses / Karl-Johan Leuchowius, Ola Söderberg, Masood Kamali-Moghaddam, Malin Jarvius, Irene Weibrecht, Katerina Pardali, Ulf Landegren -- Chapter 21. Mass Spectrometry and its Applications to Functional Proteomics / Thomas Köcher, Giulio Superti-Furga -- Chapter 22. Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Clinical Care / Minoli Perera, Federico Innocenti -- Chapter 23. Nutrigenomics: Integrating Genomic Approaches into Nutrition Research / Lynette R. Ferguson, Martin Philpott, Matthew P.G. Barnett -- Chapter 24. Novel Next-Generation DNA Sequencing Techniques for Ultra High-Throughput Applications in Bio-Medicine / Wilhelm J. Ansorge -- Chapter 25. Locus-Specific and National/Ethnic Mutation Databases: Emerging Tools for Molecular Diagnostics / George P. Patrinos -- Chapter 26. Molecular Diagnostic Applications in Forensic Science / Bruce Budowle, John V. Planz, Rowan Campbell, Arthur J. Eisenberg -- Chapter 27. Mass Disaster Victim Identification Assisted by DNA Typing / Daniel Corach -- Chapter 28. Detection of Highly Pathogenic Viral Agents: Implications for Therapeutics, Vaccines and Biodefense / Kylene Kehn-Hall, Sina Bavari -- Chapter 29. Identification of Genetically Modified Organisms / Farid E. Ahmed -- Chapter 30. Molecular Diagnostics and Comparative Genomics in Clinical Microbiology / Alex van Belkum -- Chapter 31. Genetic Monitoring of Laboratory Rodents / Jean-Louis Guénet, Fernando J. Benavides -- Chapter 32. Safety Analysis in Retroviral Gene Therapy: Identifying Virus Integration Sites in Gene-Modified Cells / Stephanie Laufs, Luisa Schubert, Patrick Maier, W. Jens Zeller, Stefan Fruehauf -- Chapter 33. Preimplantation Genetic Diagnosis / Martine de Rycke, Karen Sermon -- Chapter 34. Automated DNA Hybridization and Detection / Bert Gold -- Chapter 35. The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays / Piotr Grodzinski, Michael Ward, Robin Liu, Kathryn Scott, Saul Surrey, Paolo Fortina -- Chapter 36. Human Gene Patents and Genetic Testing / Timothy Caulfield, Yann Joly -- Chapter 37. Genetic Counseling and Ethics in Molecular Diagnostics / Mary Petrou -- Chapter 38. Genetic Testing and Psychology / Andrea Farkas Patenaude -- Chapter 39. General Considerations Concerning Safety in Biomedical Research Laboratories / William E. Grizzle, Walter C. Bell, Jerry Fredenburgh -- Chapter 40. Quality Management in the Laboratory / David Burnett.
  • 2010 Springer
    Mousumi Debnath, Godavarthi B.K.S. Prasad, Prakash S. Bisen.
  • NCBI Bookshelf
    This searchable database is a collection of in vivo molecular imaging agents developed for positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), ultrasound (US), computed tomography (CT), and optical imaging. MICAD, a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, is being developed by NCBI, the National Center for Biotechnology Information".
  • 2014 Springer Protocols
    edited by Shree Ram Singh, Vincenzo Coppola.
  • Wiley
    edited by Christof M. Niemeyer and Chad A. Mirkin.
    [v. 1]. Concepts, applications, and perspectives -- 1 . Biocompatible inorganic devices / Thomas Sawitowski -- 2. Microfluidics meets nano : lab-on-a-chip devices and their potential for nanobiotechnology / Holger Bartos, Friedrich Götz, and Ralf-Peter Peters -- 3. Microcontact printing of proteins / Emmanuel Delamarche -- 4. Cell-nanostructure interactions / Joachim P. Spatz -- 5. Defined networks of neuronal cells in vitro / Andreas Offenhäusser and Angela K. Vogt -- 6. S-Layers / Uwe B. Sleytr ... [et al.] -- 7. Engineered nanopores / Hagan Bayley ... [et al.] -- 8. Genetic approaches to programmed assembly / Stanley Brown -- 9. Microbial nanoparticle production / Murali Sastry ... [et al.] -- 10. Magnetosomes : nanoscale magnetic iron minerals in bacteria / Richard B. Frankel and Dennis A. Bazylinski -- 11. Bacteriorhodopsin and its potential in technical applications / Norbert Hampp and Dieter Oesterhelt -- 12. Polymer Nanocontainers / Alexandra Graff ... [et al.] -- 13. Biomolecular motors operating in engineered environments / Stefan Diez, Jonne H. Helenius, and Jonathon Howard -- 14. Nanoparticle-biomaterial hybrid systems for bioelectronic devices and circuitry / Eugenii Katz and Itamar Willner -- 15. DNA-protein nanostructures / Christof M. Neimeyer -- 16. DNA-templated electronics / Erez Braun and Uri Sivan -- 17. Biomimetic fabrication of DNA-based metallic nanowires and networks / Michael Mertig and Wolfgang Pompe -- 18. Mineralization in nanostructured biocompartments : biomimetic ferritins for high-density data storage / Eric L. Mayes and Stephen Mann -- 19. DNA-gold nanoparticle conjugates / C. Shad Thaxton and Chad A. Mirkin -- 20. DNA nanostructures for mechanics and computing : nonlinear thinking with life's central molecule / Nadrian C. Seeman -- 21. Nanoparticles as non-viral transfection agents / M.N.V. Ravi Kumar, Udo Bakowsky, and Claus-Michael Lehr -- 22. Luminescent quantum dots for biological labeling / Xiaohu Gao and Shuming Nie -- 23. Nanoparticle molecular labels / James F. Hainfeld, Richard D. Powell, and Gerhard W. Hacker -- 24. Surface biology : analysis of biomolecular structure by atomic force microscopy and molecular pulling / Emin Oroudjev, Signe Danielsen and Helen G. Hansma -- 25. Force spectroscopy / Markus Seitz -- 26. Biofunctionalized nanoparticles for surface-enhanced raman scattering and surface plasmon resonance / Mahnaz El-Kouedi and Christine D. Keating -- 27. Bioconjugated silica nanoparticles for bioanalytical applications / Timothy J. Drake, Xiaojun Julia Zhao, and Weihong Tan. -- v. 2. More concepts and applications -- Part I. Self-Assembly and Nanoparticles: Novel Principles -- ch. 1. Self-Assembled Artificial Transmembrane Ion Channels / Mary S. Gin, Emily G. Schmidt and Pinaki Talukdar, p. 1-15 -- ch. 2. Self-Assembling Nanostructures from Coiled-Coil Peptides / Maxim G. Ryadnov and Derek N. Woolfson, p. 17-38 -- ch. 3. Synthesis and Assembly of Nanoparticles and Nanostructures Using Bio-Derived Templates / Erik Dujardin and Stephen Mann, p. 39-63 -- ch. 4. Proteins and Nanoparticles: Covalent and Noncovalent Conjugates / Rochelle R. Arvizo, Mrinmoy De and Vincent M. Rotello, p. 65-78 -- ch. 5. Self-Assembling DNA Nanostructures for Patterned Molecular Assembly / Thomas H. LaBean, Kurt V. Gothelf and John H. Reif, p. 79-97 -- ch. 6. Biocatalytic Growth of Nanoparticles for Sensors and Circuitry / Ronan Baron, Bilha Willner and Itamar Willner, p. 99-121 -- Part II. Nanostructures for Analytics -- ch. 7. Nanoparticles for Electrochemical Bioassays / Joseph Wang, p. 123-140 -- ch. 8. Luminescent Semiconductor Quantum Dots in Biology / Thomas Pons, Aaron R. Clapp, Igor L. Medintz and Hedi Mattoussi, p. 141-157 -- ch. 9. Nanoscale Localized Surface Plasmon Resonance Biosensors / Katherine A. Willets, W. Paige Hall, Leif J. Sherry, Xiaoyu Zhang, Jing Zhao and Richard P. Van Duyne, p. 159-173 -- ch. 10. Cantilever Array Sensors for Bioanalysis and Diagnostics / Hans Peter Lang, Martin Hegner and Christoph Gerber, p. 175-195 -- ch. 11. Shear-Force-Controlled Scanning Ion Conductance Microscopy / Tilman E. Schäffer, Boris Anczykowski, Matthias Böcker and Harald Fuchs, p. 197-212 -- ch. 12. Label-Free Nanowire and Nanotube Biomolecular Sensors for In-Vitro Diagnosis of Cancer and other Diseases / James R. Heath, p. 213-232 -- ch. 13. Bionanoarrays / Rafael A. Vega, Khalid Salaita, Joseph J. Kakkassery and Chad A. Mirkin, p. 233-259 -- Part III. Nanostructures for Medicinal Applications --. ch. 14. Biological Barriers to Nanocarrier-Mediated Delivery of Therapeutic and Imaging Agents, p. 261-284 / Rudy Juliano -- ch. 15. Organic Nanoparticles: Adapting Emerging Techniques from the Electronics Industry for the Generation of Shape-Specific, Functionalized Carriers for Applications in Nanomedicine / Larken E. Euliss, Julie A. DuPont and Joseph M. DeSimone, p. 285-303 -- ch. 16. Poly(amidoamine Dendrimer-Based Multifunctional Nanoparticles / Thommey P. Thomas, Rameshwer Shukla, Istvan J. Majoros, Andrzej Myc and James R. Baker, p. 305-319 -- ch. 17. Nanoparticle Contrast Agents for Molecular Magnetic Resonance Imaging / Young-Wook Jun, Jae-Hyun Lee and Jinwoo Cheon, p. 321-346 -- ch. 18. Micro- and Nanoscale Control of Cellular Environment for Tissue Engineering / Ali Khademhosseini, Yibo Ling, Jeffrey M. Karp and Robert Langer, p. 347-364 -- ch. 19. Diagnostic and Therapeutic Targeted Perfluorocarbon Nanoparticles / Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza and Samuel A. Wickline, p. 365-380 -- Part IV. Nanomotors -- ch. 20. Biological Nanomotors / Manfred Schliwa, p. 381-399 -- ch. 21. Biologically Inspired Hybrid Nanodevices / David Wendell, Eric Dy, Jordan Patti and Carlo D. Montemagno, p. 401-418.
  • 2012 Springer
    Eran Zahavy ... [et al.], editors.
    Biomolecule/nanomaterial hybrid systems for nanobiotechnology -- Superresolution optical fluctuation imaging (SOFI) -- Application of nanoparticles for the detection and sorting of pathogenic bacteria by flow-cytometry -- Advancing nanostructured porous si-based optical transducers for label free bacteria detection -- Gold fibers as a platform for biosensing -- Surface-enhanced raman spectroscopy of organic molecules adsorbed on metallic nanoparticles -- Quantum dots and fluorescent protein FRET-based biosensors -- Semiconductor quantum dots as FRET acceptors for multiplexed diagnostics and molecular ruler application -- Assembly and microscopic characterization of DNA origami structures -- DNA nanotechnology -- Role of carbohydrate receptors in the macrophage uptake of dextran-coated iron oxide nanoparticles -- Toxicity of gold nanoparticles on somatic and reproductive cells -- Ultrasound activated nano-encapsulated targeted drug delivery and tumour cell poration -- Ultrasound mediated localized drug delivery -- Sonochemical proteinaceous microspheres for wound healing -- Alendronate liposomes for antitumor therapy: activation of [gamma] [delta] T cells and inhibition of tumor growth.
    Also available: Print – 2012
  • 2013 Springer Protocols
    edited by Sandra J. Rosenthal and David W. Wright.
    High-aspect-ratio gold nanorods : their synthesis and application to image cell-induced strain fields in collagen films / Davin J. Chernak ... [et al.] -- Imaging intracellular quantum dots : fluorescence microscopy and transmission electron microscopy / Craig J. Szymanski ... [et al.] -- Imaging of cell populations in atherosclerosis using quantum dot nanocrystals / Joshua R. Trantum and Ashwath Jayagopal -- Imaging of endothelial progenitor cell subpopulations in angiogenesis using quantum dot nanocrystals / Joshua M. Barnett, John S. Penn, and Ashwath Jayagopal -- Imaging single synaptic vesicles in mammalian central synapses with quantum dots / Qi Zhang -- Quantum dot-based single-molecule microscopy for the study of protein dynamics / Jerry C. Chang and Sandra J. Rosenthal -- Three-dimensional molecular imaging with photothermal optical coherence tomography / Melissa C. Skala ... [et al.] -- Detecting respiratory syncytial virus using nanoparticle-amplified immuno-PCR / Jonas W. Perez ... [et al.] -- Gold nanoparticle-oligonucleotide conjugates for the profiling of malignant melanoma phenotypes / John W. Stone ... [et al.] -- Methods for isolating RNA sequences capable of binding to or mediating the formation of inorganic materials / Carly Jo Carter, Alina Owczarek, and Daniel L. Feldheim -- Single-walled carbon nanotube-mediated small interfering RNA delivery for gastrin-releasing peptide receptor silencing in human neuroblastoma / Jingbo Qiao ... [et al.] -- Amino acid mediated linear assembly of au nanomaterials / Manish Sethi and Marc R. Knecht -- Enzyme-gold nanoparticle bioconjugates : quantification of particle stoichiometry and enzyme specific activity / Jacqueline D. Keighron and Christine D. Keating -- In vivo testing for gold nanoparticle toxicity / Carrie A. Simpson, Brian J. Huffman, and David E. Cliffel -- Methods for studying toxicity of silica-based nanomaterials to Living Cells / Yang Zhao ... [et al.].
  • 2006 Springer
    edited by M. Reza Mozafari.
    Also available: Print – 2006
  • 2013 Springer Protocols
    edited by Paolo Bergese, Kimberly Hamad-Schifferli.
    Preparation of 2 nm gold nanoparticles for in vitro and in vivo applications / Daniel F. Moyano, Bradley Duncan, and Vincent M. Rotello -- DNA conjugation to nanoparticles / Sunho Park -- Conjugation of nanoparticles to proteins / Marie-Eve Aubin-Tam -- Water-solubilization and functionalization of semiconductor quantum dots / Christina M. Tyrakowski, Adela Isovic, and Preston T. Snee -- Synthesizing and modifying peptides for chemoselective ligation and assembly into quantum dot-peptide bioconjugates / W. Russ Algar ... [et al.] -- Reliable methods for silica coating of au nanoparticles / Isabel Pastoriza-Santos and Luis M. Liz-Marzán -- Surface modifications by polymers for biomolecule conjugation / Laura Sola ... [et al.] -- Functionalization protocols of silicon micro/nano- mechanical biosensors / Francesca Frascella and Carlo Ricciardi -- Stability and aggregation assays of nanoparticles in biological media / James Chen Yong Kah -- Electrochemical measurements of DNA melting on surfaces / Irina Belozerova, Dongbiao Ge, and Rastislav Levicky -- Formation and characterization of the nanoparticle-protein corona / Marco P. Monopoli ... [et al.] -- Electrophoretic implementation of the solution-depletion method for measuring protein adsorption, adsorption kinetics, and adsorption competition among multiple proteins in solution / Hyeran Noh ... [et al.] -- Hyperspectral microscopy for characterization of gold nanoparticles in biological media and cells for toxicity assessment / Christin Grabinski, John Schlager, and Saber Hussain -- Immunocytochemistry, electron tomography, and energy dispersive x-ray spectroscopy (EDXS) on cryosections of human cancer cells doped with stimuli responsive polymeric nanogels loaded with iron oxide nanoparticles / Roberto Marotta ... [et al.] -- Zwitterion siloxane to passivate silica against nonspecific protein adsorption / Zaki G. Estephan and Joseph B. Schlenoff -- Preparation and characterization of DNA block copolymer assemblies loaded with nanoparticles / Xi-Jun Chen, Robert J. Hickey, and So-Jung Park -- Polyaspartic acid coated iron oxide nanoprobes for PET/MRI imaging / Taku Cowger and Jin Xie -- Ligand synthesis and passivation for silver and large gold nanoparticles for single-particle-based sensing and spectroscopy / Daniel Montiel ... [et al.] -- Noncovalent intracellular drug delivery of hydrophobic drugs on au NPs / Tennyson Doane and Clemens Burda -- Modification of carbon nanotubes for gene delivery vectors / Victor Ramos-Perez ... [et al.] -- Lipid-based nanoparticles as nonviral gene delivery vectors / Daniele Pezzoli ... [et al.] -- Stabilizing gold nanoparticle bioconjugates in physiological conditions by PEGylation / Joan Comenge and Víctor F. Puntes.
  • 2007 Springer
    edited by M. Resa Mozafari.
    Micro and nano systems in biomedicine and drug delivery / Nesrin Hasirci -- Newlipid- and glycolipid-based nanosystems for targeted gene delivery: cholenims, glycoclips, and chitosan / R.I. Zhdanov ... [et. al] -- Artificial implants - new developments and associated problems / Abdelwahab Omri -- Niosomes as nanocarrier systems / Nefise Ozlen Sahin -- Starch - a potential biomaterial for biomedical application / Lovedeep Kaur, Jaspreet Singh, Qiang Liu -- Alternative applications for drug delivery: nasal and pulmonary routes / A. Yekta Ozer -- An overview of lipsome-derived nanocarrier technologies / M. Reza Mozafari, Kianoush Khosravi-Darani -- Uptake studies of free and liposomal sclareol by MCF-7 and H-460 human cancer cell lines / Agnes Paradissi ... [et. al] -- Release advantages of a liposomal dendrimer- doxorubicin complex, over conventional liposomal formulation of doxorubicin / Aristarchos Papagiannoros, Costas Demetzos -- Applications of light and electron microscopic techniques in liposome research / A. Yekta Ozer.
  • 2012 Springer Protocols
    edited by Maria E. Gracheva.
    Detecting and characterizing individual molecules with single nanopores -- Protein sensing with engineered protein nanopores -- Measurements of DNA immobilized in the alpha-hemolysin nanopore -- DNA unzipping and protein unfolding using nanopores -- DNA characterization with ion beam-sculpted silicon nitride nanopores -- DNA sequencing by nanopore-induced photon emission -- Optical tweezers for mechanical control over DNA in a nanopore -- Analyzing single DNA molecules by nanopore translocation -- DNA characterization by transverse electrical current in a nanochannel -- Optimization of the molecular dynamics method for simulations of DNA and ion transport through biological nanopores -- Polymer translocation through an electrically tunable nanopore in a multilayered semiconductor membrane -- Graphene nanopore devices for DNA sensing -- Measuring single-wall carbon nanotubes with solid-state nanopores -- Passive and electrically actuated solid-state nanopores for sensing and manipulating DNA.
  • 2011 Springer Protocols
    edited by Ping Wang.
    Nanoscale-engineered cytochrome P450 system with a branch structure / Hidehiko Hirakawa and Teruyuki Nagamune -- Chemically induced self-assembly of enzyme nanorings / Brian R. White, Qing Li, and Carston R. Wagner -- Self-assemblies of polymer-enzyme conjugates at oil-water interfaces for interfacial biocatalysis / Guangyu Zhu and Ping Wang -- Molecular assembly-assisted biocatalytic reactions in ionic liquids / Muhammad Moniruzzaman and Masahiro Goto -- Organic-soluble enzyme nano-complexes formed by ion-pairing with surfactants / Songtao Wu, Andreas Buthe, and Ping Wang -- Enzyme-immobilized CNT network probe for in vivo neurotransmitter detection / Gi-Ja Lee [and others] -- Kinesin I ATPase manipulates biohybrids formed from tubulin and carbon nanotubes / Cerasela Zoica Dinu [and others] -- Reversible his-tagged enzyme immobilization on functionalized carbon nanotubes as nanoscale biocatalyst / Liang Wang and Rongrong Jiang -- TiO2 nanoparticle system for sacrificial solar H2 production prepared by rational combination of a hydrogenase with a ruthenium photosensitizer / Erwin Reisner and Fraser A. Armstrong -- Preparation and characterization of single-enzyme nanogels / Jun Ge [and others] -- Fabrication and characterization of bioactive thiol-silicate nanoparticles / Frances Neville and Paul Millneri -- Immobilization of enzymes on fumed silica nanoparticles for applications in nonaqueous media / Juan C. Cruz [and others] -- Microencapsulation of bioactive nanoparticles / Fei Gao, Ping Wang, and Guanghui Ma -- Engineering the logical properties of a genetic and gate / Daniel J. Sayut, Yan Niu, and Lianhong Sun -- Strain engineering strategies for improving whole-cell biocatalysis : engineering Escherichia coli to overproduce xylitol as an example / Jonathan W. Chin and Patrick C. Cirino -- Enzyme-carrying electrospun nanofibers / Hongfei Jia -- Uniform lab-scale biocatalytic nanoporous latex coatings for reactive microorganisms / Jimmy L. Gosse and Michael C. Flickinger -- Entrapment of enzymes in nanoporous sol-gels / Andreas Buthe.
  • 2005 CRCnetBASE
    edited by Ralph S. Greco, Fritz B. Prinz, R. Lane Smith.
  • 2013 Springer Protocols
    edited by Manfred Ogris, David Oupicky.
    Toxicological aspects for nanomaterial in humans -- Lactate dehydrogenase assay for assessment of polycation cytotoxicity -- Combined fluorimetric caspase 3/7 assay and bradford protein determination for assessment of polycation-mediated cytotoxicity -- Anti-PEG igm production via a PEGylated nano-carrier system for nucleic acid delivery -- Near-infrared optical imaging of nucleic acid nanocarriers in vivo -- Lipids for nucleic acid delivery: Synthesis and particle formation -- Histidine-rich cationic amphipathic peptides for plasmid DNA and siRNA delivery -- Synthesis of polyethylenimine-based nanocarriers for systemic tumor targeting of nucleic acids -- Synthesis of bioreducible polycations with controlled topologies -- Lyophilization of synthetic gene carriers -- Surface- and hydrogel-mediated delivery of nucleic acid nanoparticles -- Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids -- In situ AFM analysis investigating disassembly of DNA nanoparticles and nano-films -- Enhancing nucleic acid delivery with ultrasound and microbubbles -- Magnetic and acoustically active microbubbles loaded with nucleic acids for gene delivery -- Synthesis of lipidic magnetic nanoparticles for nucleic acid delivery -- Lipopeptide delivery of siRNA to the central nervous system -- Flow cytometry-based cell type-specific assessment of target regulation by pulmonary siRNA delivery -- Liver-targeted gene delivery through retrograde intrabiliary infusion.
  • 2012 Springer Protocols
    edited by Melba Navarro, Josep A. Planell.
    Is nanotechnology the key to unravel and engineer biological processes? -- Synthesis of genetically engineered protein polymers (recombinamers) as an example of advanced self-assembled smart materials -- Design of biomolecules for nanoengineered biomaterials for regenerative medicine -- Stimuli responsive polymers for nanoengineering of biointerfaces -- Micro/nanopatterning of proteins using a nanoimprint-based contact printing technique -- Functionalization of surfaces with synthetic oligonucleotides -- Fabrication of PEG hydrogel microwell arrays for high-throughput single stem cell culture and analysis -- Preparation of polyelectrolyte nanocomplexes containing recombinant human hepatocyte growth factor as potential oral carriers for liver regeneration -- Electrospinning technology in tissue regeneration -- Protein adsorption characterization -- Measuring wettability of biosurfaces at the microscale -- AFM to study bio/nonbio interactions -- Evaluation of cytocompatibility and cell response to boron nitride nanotubes -- Nanobiosensors for in vitro and in vivo analysis of biomolecules -- Novel strategies to engineering biological tissue in vitro -- Enabling biomedical research with designer quantum dots -- The role of nanophotonics in regenerative medicine -- Molecular dynamics methods for modeling complex interactions in biomaterials -- Regenerative nanomedicine: ethical, legal, and social issues.
  • 2009 ebrary
    Amalya Lumerman Oliver.
    Networks, collaborations, and learning and knowledge-creation -- The biotechnology industry through the lenses of organizational and networks scholarship -- New organizational forms for knowledge-creation in biotechnology -- Scientific entrepreneurship -- Science and discoveries in the context of private and public knowledge-creation and learning -- The search for university-industry collaborations : linear and chaotic networking processes -- Trust in collaborations and the social structure of academic research -- Organizational learning and strategic alliances : recombination and duality of competition and collaboration -- Further directions for understanding interorganizational collaborations and learning.
  • 2011
    Dongjun Shin.
    The increasing demand for physical interaction between humans and robots has led to an interest in robots whose behavior is guaranteed to be safe when they are in close proximity with humans. However, attaining sufficiently high levels of performance while ensuring safety creates formidable challenges in mechanical design, actuation, sensing, and control. To promote safety without compromising performance, a new actuation concept, referred to as hybrid actuation, has been developed. Since low impedance output at high frequencies is essential for robot safety, while optimal passive stiffness is needed for robot performance, the new actuation approach employs a pneumatic artificial muscle as a macro actuator to provide low-frequency torques. Artificial pneumatic muscles provide high force-to-weight ratio and inherent compliance, both of which allow for low impedance actuation. To compensate for the slow and non-linear dynamics of pneumatic actuation, a small electromagnetic actuator collocated at the robot's joint is employed as a mini actuator, which provides high mechanical bandwidth for high performance without increasing the inertia and size of the manipulator. To achieve the appropriate balance between safety and performance, design methodologies were developed that optimally determine key design parameters such as the required mini motor torque capacity, the joint stiffness introduced by an antagonistic pair of muscles, and the pulley radius. Using a testbed, referred to as the Stanford Safety Robot (S2rho), the hybrid actuation was evaluated for position tracking performance, force tracking performance, and impact behavior. The experimental results demonstrate that by significantly improving control performance with the hybrid actuation over performance with pneumatic muscles alone, while reducing the effective inertia significantly, the competing design objectives of safety and performance can be successfully integrated into a single robotic manipulator. As an extension of the hybrid actuation concept, the new design of dual four-degree-of-freedom robotic arms with torso is presented and detailed descriptions of the design are included.
  • 2008 Karger
    volume editors, Philippe Poindron, Pascale Piguet.
    Theoretical considerations on animal models / Poindron, P., Callizot, N., Piguet, P. -- Mouse models with motor neuron defects as a tool for deciphering amyotrophic lateral sclerosis. Applications, limits, and future challenges / Echaniz-Laguna, A. ... [et al.] -- A chronic relapsing animal model for multiple sclerosis. Myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis in dark agouti rats / Kinter, J., Zeis, T., Schaeren-Wiemers, N. -- Occlusion of the middle cerebral artery in rats. Refinement of an animal model for human stroke / Cam, E. ... [et al.] -- Pyridoxine-induced peripheral neuropathy. Animal models and uses / Callizot, N., Poindron, P. -- A dopamine-sensitive inherited motor syndrome linked to the frissonnant mutation / Callizot, N., Guenet, J.-L., Poindron, P.
  • 2012 Springer
    Avi Ma'ayan, Ben D. MacArthur, editors.
    Gene Expression Profiling and Regulatory Networks in Single Cells / Fumio Arai, Kentaro Hosokawa, Yoshiko Matsumoto, Hirofumi Toyama and Toshio Suda -- Cell Fate Regulatory Networks / Sonya J. Ridden and Ben D. MacArthur -- Noise in Regulatory Networks / Srinandan Dasmahapatra -- Generalised Modelling in Systems Biology / Thilo Gross -- Relative Quantification Mass Spectrometry Using iTRAQ Isobaric Tags / Richard D. Unwin, Emma Carrick and Anthony D. Whetton -- Deciphering Protein Complexes and Protein Interaction Networks for Stem Cell Pluripotency / Jianlong Wang -- Omics Era in Stem Cell Research: Data Integration of Multi-regulatory Layers / Ana Sevilla, Benjamin Trinite and Ihor R. Lemischka -- High Throughput Affinity Purification and Mass Spectrometry to Determine Protein Complex Interactions / Anna Malovannaya, Rainer B. Lanz, Bert W. O'Malley and Jun Qin -- Network Pharmacology to Aid the Drug Discovery Process / Ruth Dannenfelser, Huilei Xu, Catherine Raimond and Avi Ma'ayan -- What Can Networks Do for You? / Bernhard M. Schuldt, Franz-Josef Müller and Andreas A. Schuppert.
  • 2007 ScienceDirect
    editor, Keith R. Mitchelson.
    Overview: developments in DNA sequencing / Keith R. Mitchelson ... [et al.] -- Chip capillary electrophoresis and total genetic analysis systems / Quiang Xiong and Jing Cheng -- Comparative sequence analysis by MALDI-TOF mass spectrometry: utilizing the known to discover the new / Mathias Ehrich, Franz Hillenkamp, and Dirk van den Boom -- Advances in dye-nucleotide conjugate chemistry for DNA sequencing / Shiv Kumar and Carl W. Fuller -- The 454 life sciences picoliter sequencing system / Marcel Margulies ... [et al.] -- An integrated system for DNA sequencing by synthesis / John R. Edwards, Dae Hyun Kim, and Jingyue Ju -- Single-molecule fluorescence microscopy and its applications to single-molecule sequencing by cyclic synthesis / Benedict Hebert and Ido Braslavsky -- Rapid DNA sequencing by direct nanoscale reading of nucleotide bases on individual DNA chains / James Weifu Lee and Amit Meller -- A single molecule system for whole genome analysis / Shiguo Zhou, Jill Herschleb, and David C. Schwartz -- Sequencing aided by mutagenesis facilitates the de novo sequencing of megabase DNA fragments by short read lengths / Jonathan M. Keith ... [et al.] -- Genome sequencing and assembly / Annette McGrath -- Valid recovery of nucleic acid sequence information from high contamination risk samples: ancient DNA and environmental DNA / George A. Kowalchuk ... [et al.].
  • 2005 Karger
    volume editors, Philippe Poindron, Pascale Piguet, Eckart Förster.
    Hippocampal slice cultures / Förster, E., Bartos, M., Zhao, S. -- Protocol for the primary culture of cortical neurons / Gonthier, B. ... [et al.] -- A new technique to control the architecture of neuronal networks in vitro / Wyart, C. ... [et al.] -- Organotypic cultures of the rat retina / Hofmann, H.-D. ... [et al.] -- Cerebellar slice cultures / Kapfhammer, J.P. -- Culture of dissociated hippocampal neurons / Rigato, F. -- Improved methods for culturing rat and mouse motor neurons. Their applications / Guettier-Sigrist, S. ... [et al.] -- Characterization of long-term cultured cell lines of murine microglia called MAMI. The case for MAMI-96 cell line / Laporte, V. ... [et al.].
  • 2012 Springer Protocols
    edited by Jian-Bing Fan.
    Controlling miRNA regulation in disease / Willemijn M. Gommans and Eugene Berezikov -- Introduction to miRNA profiling technologies and cross-platform comparison / Sarah Aldridge and James Hadfield -- Stem-loop RT-qPCR for microRNA expression profiling / James Hurley [and others] -- Poly(T) adaptor RT-PCR / Rui-Shi [and others] -- MicroRNA in situ hybridization / Boye Schnack Nielsen -- Agilent microRNA microarray profiling system / Petula N. D'Andrade and Stephanie Fulmer-Smentek -- MiRNA expression profiling using Illumina Universal BeadChips / Jing Chen, Craig S. April, and Jian-Bing Fan -- MicroRNA expression analysis using the Affymetrix platform / Suzanne Dee and robert C. Getts -- Individualized miRNA assay panels using optically encoded beads / Keld Sorensen -- Microfluidic primer extension assay / Markus Beier and Valesca Boisguérin -- MicroRNA profiling using [mu]Paraflo microfluidic array technology / Xiaochuan Zhou [and others] -- MicroRNA expression analysis using the Illumina microRNA-Seq platform / Shujun Luo -- Next-generation sequencing of miRNAs with Roche 454 GS-FLX technology : steps for a successful application / Ana Raquel Soares, Patrícia M. Pereira, and Manuel A.S. Santos -- Methods for small RNA preparation for digital gene expression profiling by next-generation sequencing / Sam E.V. Linsen and Edwin Cuppen -- Profiling of short RNAs using Helicos single-molecule sequencing / Philipp Kapranov, Fatih Ozsolak, and Patrice M. Milos -- DeepBASE : annotation and discovery of microRNAs and other noncoding RNAs from deep-sequencing data / Jian-Hua Yang and Liang-Hu Qu -- PhenomiR : microRNAs in human diseases and biological processes / Andreas Ruepp, Andreas Kowarsch, and Fabian Theis -- MiRNA expression profiling : from reference genes to global mean normalization / Barbara D'haene [and others] -- MiRNA data analysis : next-gen sequencing / Preethi H. Gunaratne [and others] -- Integrated miRNA expression analysis and target prediction / William Ritchie and John E.J. Rasko -- MiRNAs in human cancer / Xiaomin Zhong, George Coukos, and Lin Zhang -- Blood-based miRNA preparation for noninvasive biomarker development / Svenja Debey-Pascher [and others].
  • 2011 Springer
    Justin Ainscough, Shinya Yamanaka, Takashi Tada, editors.
    Annotation Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mechanisms that drive disease aetiology the research is realistically opening the doors for development of targeted and personalized therapeutic applications that many considered, until recently, to be nothing more that a far fetched dream. This volume provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years. Since the early 1950s a small number of notable experiments have provided significant impetus to the field, primarily the demonstration of reprogramming ability, first by the complex cytoplasmic milieu that constitutes the amphibian egg, then that of the mammalian egg, and finally that of the mammalian embryonic stem cell. Most recently, the demonstration that a limited pool of defined molecules is capable of reprogramming a multitude of cell types has provided massive impetus and facilitated transition towards realistic therapeutic application. We have therefore reproduced some of the key articles that elegantly document these dramatic stages of development of the field in an inclusive appendix to the book, for the benefit of readers keen to investigate the history of how the field of stem cell biology has evolved. Owing to the ever broadening nature of this field, and the incredible rate at which it is evolving, the main content of this volume focuses on areas that have shown significant movement in recent years, are most likely to translate into personalized therapeutic application, and thus provide greatest potential for significant impact on human health in the not too distant future. We recognize that research into many other disease states and cell types are all equally worthy of discussion. We would therefore like to acknowledge those researchers involved whose work we have not been able to include in this volume. Nuclear Reprogramming and Stem Cells will serve as a valuable resource for all researchers in the field of stem cell biology, including those just setting out on their career path as well as those already established in the field.
  • 2006 CRCnetBASE
    edited by Fereidoon Shahidi
    1. Nutraceutical and Specialty Lipids / Fereidoon Shahidi and S.P.J.N. Senanayake -- 2. Medium-Chain Triacylglycerols / Yaakob B. Che Man and Marina Abdul Manaf -- 3. Cereal Grain Oils / Roman Przybylski -- 4. Fruit Seed Oils / Liangli Yu, John W. Parry, and Kequan Zhou -- 5. Minor Specialty Oils / Frank D. Gunstone -- 6. Sphingolipids / Fang Fang, Hang Chen, Chi-Tang Ho, and Robert T. Rosen -- 7. Modification and Purification of Sphingolipids and Gangliosides / Scott Bloomer -- 8. Hydroxy Fatty Acids / Thomas A. McKeon, Charlotta Turner, Xiaohua He, Grace Chen, and Jiann-Tsyh Lin -- 9. Tree Nut Oils and Byproducts: Compositional Characteristics and Nutraceutical Applications / Fereidoon Shahidi and H. Miraliakbari -- 10. Gamma-Linolenic Acid (GLA) / Yao-wen Huang and Chung-yi Huang -- 11. Diacylglycerols (DAGs) and their Mode of Action / Brent D. Flickinger -- 12. Conjugated Linoleic Acids (CLAs): Food, Nutrition, and Health / Bruce A. Watkins and Yong Li -- 13. Occurrence of Conjugated Fatty Acids in Aquatic and Terrestrial Plants and their Physiological Effects / Bhaskar Narayan, Masashi Hosokawa, and Kazuo Miyashita -- 14. Marine Conjugated Polyunsaturated Fatty Acids / Yasushi Endo, Si-Bum Park, and Kenshiro Fujimoto -- 15. Marine Oils: Compositional Characteristics and Health Effects / Fereidoon Shahidi and H. Miraliakbari -- 16. Single-Cell Oils as Sources of Nutraceutical and Specialty Lipids: Processing Technologies and Applications / S.P.J.N. Senanayake and Jaouad Fichtali -- 17. Emulsions for the Delivery of Nutraceutical Lipids / Karlene S.T. Mootoosingh and Dérick Rousseau -- 18. Lipid Emulsions for Total Parenteral Nutrition (TPN) Use and as Carriers for Lipid-Soluble Drugs / Hu Liu and Lili Wang -- 19. Modified Oils / Frank D. Gunstone -- 20. Fat Replacers: Mimetics and Substitutes / Barry G. Swanson -- 21. Application of Functional Lipids in Foods / Charlotte Jacobsen, Maike Timm-Heinrich, and Nina Skall Nielsen -- 22. Application of Multistep Reactions with Lipases to the Oil and Fat Industry / Yuji Shimada, Toshihiro Nagao, and Yomi Watanabe -- 23. Structure-Related Effects on Absorption and Metabolism of Nutraceutical and Specialty Lipids / Armand B. Christophe -- 24. Lipid Oxidation in Specialty Oils / Karen Schaich -- 25. Trans Fatty Acids in Specialty Lipids / G.R. List, R.O. Adlof, and J.W. King -- 26. Tocopherols and Tocotrienols as Byproducts of Edible Oil Processing / Vitamin E: A New Perspective Andreas M. Papas -- 27. Plant Sterols and Steryl Esters in Functional Foods and Nutraceuticals / Nikolaus Weber and Kumar D. Mukherjee -- 28. Phospholipids/Lecithin: A Class of Nutraceutical Lipids / Frank T. Orthoefer and G.R. List -- 29. Centrifugal Partition Chromatography (CPC) as a New Tool for Preparative-Scale Purification of Lipid and Related Compounds / Udaya Wanasundara and Paul Fedec -- 30. Oilseed Medicinals: Applications in Drugs and Functional Foods / Robert D. Reichert.
  • 2012 CRCnetBASE
    edited by Debmalya Barh, Kenneth Blum, Margaret Anne Madigan.
    Section 1. Methodology and application -- section 2. Empirical research -- section 3. Computational and systems biology -- section 4. Therapeutics -- section 5. Future perspective.
  • 2013 Springer
    Debmalya Barh, Dipali Dhawan, Nirmal Kumar Ganguly, editors.
    Omics for Personalized Medicine will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.
  • 2015 Springer Protocols
    edited by Santi M. Spampinato.
    Overview of genetic analysis of human opioid receptors / Santi M. Spampinato -- Computational structural biology of opioid receptors / Davide Provasi -- Analysis of epigenetic mechanisms regulating opioid receptor gene transcription / Cheol Kyu Hwang [and three others] -- Renilla luciferase reporter assay to study 3'UTR-Driven posttranscriptional regulations of OPRM1 / Gabriele Vincelli and Andrea Bedini -- High-throughput gene expression profiling of opioid-induced alterations in discrete brain areas / Michal Korostynski [and three others] -- Real-time imaging of mu opioid receptors by total internal reflection fluorescence microscopy / Cristina Roman-Vendrell and Guillermo Ariel Yudowski -- In vivo techniques to investigate the internalization profile of opioid receptors / Amynah A. Pradhan [and three others] -- Monitoring opioid receptor dimerization in living cells by bioluminescence resonance energy transfer (BRET) / Monica Baiula -- Analysis of potassium and calcium imaging to assay the function of opioid receptors / Viola Spahn, Dinah Nockemann, and Halina Machelska -- Electrophysiological patch clamp assay to monitor the action of opioid receptors / Viola Spahn, Dinah Nockemann, and Halina Machelska -- Skin-nerve preparation to assay the function of opioid receptors in peripheral endings of sensory neurons / Rabih Moshourab, Yvonne Schmidt, and Halina Machelska -- Mechanical nociception measurement in mice and rats with automated Von Frey equipment / Gabriele Campana and Roberto Rimondini -- Detecting zinc release induced by mu-opioid receptor agonists in brain slices / María Rodríguez-Muñoz [and three others] -- Opioid receptors : methods for detection and their modes of actions in the eye / Shahid Husain -- Evaluation of murine macrophage cytokine production after in vivo morphine treatment / Silvia Franchi [and four others] -- Measurement of macrophage toll-like receptor 4 expression after morphine treatment / Mara Castelli [and three others] -- The role of opioid receptors in migration and wound recovery in vitro in cultured human keratinocytes and fibroblasts / Mei Bigliardi-Qi and Paul L. Bigliardi -- Role of opioid receptors in the reinstatement of opioid- seeking behavior : an overview / Liana Fattore [and three others] -- Analysis of opioid-seeking reinstatement in the rat / Liana Fattore [and three others] -- Induction of a high alcohol consumption in rats and mice : role of opioid receptors / Roberto Rimondini and Gabriele Campana -- Evaluation of social and nonsocial behaviors mediated by opioids in mouse pups / Francesca R. D'Amato.
  • 2014 CRCnetBASE
    edited by Stephen P. Morgan, Felicity R.A.J. Rose, Stephen J. Matcher.
    "This book is focused on the optical techniques that can be applied to regenerative medicine, including optical coherence tomography, acousto-optic imaging, Raman spectroscopy, machine vision, polarized light imaging, fibre optic sensors, second harmonic generation, multi-photon microscopy, coherent anti-Stokes Raman scattering, and polarized light imaging. It covers applications both in fundamental research and in the regenerative medicine industry for tissue engineering products. Each chapter gives an overview of a particular technique, its advantages and limitations in terms of structural and functional information provided, and examples of applications in regenerative medicine. The book provides a practical guide to the most appropriate techniques for a given application. It also offers a summary of major recent advances, such as use of machine vision for tracking growth of three-dimensional constructs in bioreactors and polarization sensitive optical coherence tomography for monitoring collagen alignment in cartilage growth"--Provided by publisher.
  • 2013 Springer Protocols
    edited by Joydeep Basu, John W. Ludlow.
    1. Isolation and characterization of human adipose-derived stem cells for use in tissue engineering / Benjamin M. Buehrer and Bentley Cheatham -- 2. Isolation of smooth muscle cells from bladder for generation of engineered urologic organs / Darell W. McCoy -- 3. Isolation of urothelial cells from bladder tissue / Namrata Sangha -- 4. Isolation of pulsatile cell bodies from esophageal tissue / John W. Ludlow, Joydeep Basu, Christopher W. Genheimer, Kelly I. Guthrie, and Namrata Sangha -- 5. Cell isolation through whole-liver perfusion and preparation of hepatocytes for cytochrome P450 analysis / Sonya O. Meheux -- 6. Ex vivo culture and separation of functional renal cells / Andrew T. Bruce, Kelly I. Guthrie, and Rusty Kelley -- 7. Isolation and myogenic differentiation of mesenchymal stem cells for urologic tissue engineering / Rongpei Wu, Guihua Liu, Shantaram Bharadwaj and Yuanyuan Zhang -- 8. Xeno-free adaptation and culture of human pluripotent stem cells / Tori Sampsell-Barron -- 9. Reverse engineering life : physical and chemical mimetics for controlled stem cell differentiation into cardiomyocytes / Gary R. Skuse and Kathleen A. Lamkin-Kennard -- 10. Phenotypic analysis of bioactive cells for application in regenerative medicine / Teresa Bora Burnette and Andrew T. Bruce -- 11. Preparation and evaluation of natural scaffold materials for kidney regenerative applications / Monica A. Serban, Toyin A. Knight, and Richard G. Payne -- 12. Rapid production of autologous fibrin hydrogels for cellular encapsulation in organ regeneration / Adelola O. Oseni, Peter E. Butler, and Alexander M. Seifalian -- 13. Electrospinning tubular scaffolds with tissue-like mechanical properties and biomimetic surface features / Scott Rapoport -- 14. Design, fabrication, and preparation of synthetic scaffolds for urologic tissue engineering / Richard G. Payne and Toyin A. Knight -- 15. Characterization of a PGA-based scaffold for use in a tissue-engineered neo-urinary conduit / Toyin A. Knight and Richard G. Payne -- 16. Migration assay to evaluate cellular interactions with biomaterials for tissue engineering/regenerative medicine applications / Kelly I. Guthrie, Namrata Sangha, Christopher W. Genheimer, Joydeep Basu, and John W. Ludlow -- 17. Care of rodent models used for preclinical evaluation of tissue-engineered/regenerative medicine product candidates / Kim L. Mihalko -- 18. Bioreactor design considerations for hollow organs / Jeff Fish, Craig Halberstadt, Darell W. McCoy and Neil Robbins -- 19. Construction of a multicoaxial hollow fiber bioreactor / Randall McClelland, Katherine Tech, and Jeffrey M. Macdonald -- 20. Isolation of human cadaveric pancreatic islets for clinical transplantation / Craig Halberstadt, Deana Williams, and Paul Gores -- 21. Microencapsulation of pancreatic islets for use in a bioartificial pancreas / Emmanuel C. Opara, John P. McQuilling, and Alan C. Farney -- 22. Bioengineered skin substitutes / Pedro Lei, Hui You, and Stelios T. Andreadis -- 23. Formulation of selected renal cells for implantation into a kidney / Craig Halberstadt, Neil Robbins, Darrell W. McCoy, Kelly I. Guthrie, Andrew T. Bruce, Toyin A. Knight and Richard G. Payne -- 24. Human liver bioengineering using a whole liver decellularized bioscaffold / Pedro M. Baptista, Dipen Vyas, Emma Moran, Zhan Wang and Shay Soker -- 25. A "living bioreactor" for the production of tissue-engineered small intestine / Daniel E. Levin, Frederic G. Sala, Erik R. Barthel, Allison L. Speer, Xiaogang Hou, Yasuhiro Torshima and Tracy C. Grikscheit -- 26. Tissue engineering of esophagus and small intestine in rodent injury models / Joydeep Basu, Kim L. Mihalko, Elias A. Rivera, Kelly I. Guthrie, Christopher W. Genheimer, Namrata Sangha and John W. Ludlow -- 27. Scanning electron microscopy evaluation of endothelialized tissue-engineered constructs / Sandra L. Johnson -- 28. Genotypic and phenotypic analysis of in vivo tissue regeneration in an animal model / Christopher W. Genheimer -- 29. Histological evaluation of tissue regeneration using biodegradable scaffold seeded by autologous cells for tubular/hollow organ applications / Elias A. Rivera and Manuel J. Jayo.
  • 2005 CRCnetBASE
    edited by Sachdev S. Sidhu.
  • 2009 Springer
    edited by Carlos A. Guzman, Giora Z. Feuerstein.
    Translational medicine: a paradigm shift in modern drug discovery and development: the role of biomarkers / Mark Day, J. Lynn Rutkowski, and Giora Z. Feuerstein -- Natural products in drug discovery: present status and perspectives / Gabriella Molinari -- Protein pharmaceuticals: discovery and preclinical development / Davinder S. Gill -- The role of nanobiotechnology in drug discovery / Kewal K. Jain -- Conotoxin venom peptide therapeutics / Richard J. Lewis -- Shark novel antigen receptors: the next generation of biologic therapeutics? / Caroline Barelle, Davinder Gill, and Keith Charlton -- Immune interventions of human diseases through toll-like receptors / Cevayir Coban, Ken J. Ishii, and Shizuo Akira -- Genome-based vaccine development: a short cut for the future / Danilo Gomes Moriel ... [et al.] -- The antigenome: from protein subunit vaccines to antibody treatments of bacterial infections? / Carmen Giefing, Eszter Nagy, and Alexander von Gabain -- HSV as a vector in vaccine development and gene therapy / Peggy Marconi ... [et al.] -- Virus-like particles as a vaccine delivery system: myths and facts / Polly Roy and Rob Noad -- Applications of bacterial ghosts in biomedicine / Petra Lubitz, Ulrike Beate Mayr, and Werner Lubitz -- Immune modulators with defined molecular targets: cornerstone to optimize rational vaccine design / Thomas Ebensen and Carlos A. Guzmøn -- Innovative approaches to develop prophylactic and therapeutic vaccines against HIV/AIDS / Aurelio Cafaro ... [et al.] -- New strategies to overcome the drawbacks of currently available flu vaccines / Epifanio Fichera ... [et al.].
    Also available: Print – 2009
  • 2006 CRCnetBASE
    edited by Michael J. Groves.
  • 2006 Springer
    edited by Jan J. Dubowski and Stoyan Tanev.
  • 2006 Wiley
    Richard S. Quimby.
    Part 1. Propagation of light -- ch. 1. Overview -- ch. 2. Review of optics -- ch. 3. Planar waveguides -- ch. 4. Cylindrical waveguides -- ch. 5. Losses in optical fibers -- ch. 6. Dispersion in optical fibers -- ch. 7. Fiber connections and diagnostics -- ch. 8. Photonic crystal optics -- ch. 9. Nonlinear optics -- Part 2. Generation and Detection of Light -- ch. 10. Review of semiconductor physics -- ch. 11. Light sources -- ch. 12. Light source to waveguide coupling efficiency -- ch. 13. Optical detectors -- ch. 14. Photodiode detectors -- Part 3. Laser light -- ch. 15. Lasers and coherent light -- ch. 16. Optical resonators -- ch. 17. Guassian beam optics -- ch. 18. Stimulated emission and optical gain -- ch. 19. Optical amplifiers -- ch. 20. Laser oscillation -- ch. 21. CW laser characteristics -- ch. 22. Pulsed lasers -- ch. 23. Survey of laser types -- Part 4. Light-based communications -- ch. 24. Optical communications -- Appendix A. Solid angle and the brightness theorem -- Appendix B. Fourier synthesis and the uncertainty relation.
  • 2011 CRCnetBASE
    edited by Christine E. Pullar.
    Measuring endogenous electric fields / Richard Nuccitelli -- Investigation systems to study the biological effects of weak physiological electric fields / Francis X. Hart -- Endogenous bioelectric signals as morphogenetic controls of development, regeneration, and neoplasm / Michael Levin -- Stem cell physiological responses to noninvasive electrical stimulation / Igor Titushkin ... [et al.] -- Electrical signals control corneal epithelial cell physiology and wound repair / Colin D. McCaig -- Physiological electric fields can direct keratinocyte migration and promote healing in chronic wounds / Christine E. Pullar -- Electrical control of angiogenesis / Entong Wang ... [et al.] -- Inflammatory cell electrotaxis / Francis Lin and Christine E. Pullar -- Effects of DC electric fields on migration of cells of the musculoskeletal system / Najmuddin J. Gunja, Clark T. Hung, and J. Chlöe Bulinski -- Neuronal growth cone guidance by physiological DC electric fields / Ann M. Rajnicek -- Can applied voltages be used to produce spinal cord regeneration and recovery in humans? / Richard Ben Borgens -- Bioelectricty of cancer : voltage-gated ion channels and direct-current electric fields / Mustafa B. A. Djamgoz.
  • 2007 Springer Protocols
    edited by Neil Willey.
  • 2016 Springer Protocols
    edited by David Edwards.
    Using GenBank / Eric W. Sayers and Ilene Karsch-Mizrachi -- UniProtKB/Swiss-Prot, the manually annotated section of the UniProt knowledgebase : how to use the entry view / Emmanuel Boutet ... [et al.] -- KEGG bioinformatics resource for plant genomics and metabolomics / Minoru Kanehisa -- Plant pathway databases / Pankaj Jaiswal and Björn Usadel -- Plant ontology : a tool for plant genomics / Laurel Cooper and Pankaj Jaiswal -- Ensembl plants : integrating tools for visualizing, mining, and analyzing plant genomics data / Dan Bolser ... [et al.] -- Gramene : a resource for comparative analysis of plants genomes and pathways / Marcela Karey Tello-Ruiz ... [et al.] -- PGSB/MIPS plant genome information resources and concepts for the analysis of complex grass genomes / Manuel Spannagl ... [et al.] -- MaizeGDB : the maize genetics and genomics database / Lisa Harper ... [et al.] -- WheatGenome.info : a resource for wheat genomics resource / Kaitao Lai -- User guidelines for the brassica database : BRAD / Xiaobo Wang, Feng Cheng, and Xiaowu Wang -- TAG sequence identification of genomic regions using TAGdb / Pradeep Ruperao -- Short read alignment using SOAP2 / Bhavna Hurgobin -- Tablet : visualizing next-generation sequence assemblies and mappings / Iain Milne ... [et al.] -- Analysis of genotyping-by-sequencing (GBS) data / Sateesh Kagale ... [et al.] -- Skim-based genotyping by sequencing using a double haploid population to call SNPs, infer gene conversions, and improve genome assemblies / Philipp Emanuel Bayer -- Finding and characterizing repeats in plant genomes / Jacques Nicolas, Pierre Peterlongo, and Sébastien Tempel -- Analysis of RNA-Seq data using TopHat and cufflinks / Sreya Ghosh and Chon-Kit Kenneth Chan.
  • 2007 Springer Protocols
    edited by David Edwards.
    The EMBL nucleotide sequence and genome reviews databases / Peter Sterk ... [et al.] -- Using GenBank / David Wheeler -- A collection of plant-specific genomic data and resources at NCBI / Tatiana Tatusova, Brian Smith-White, and James Ostell -- UniProtKB/Swiss-Prot / Emmanuel Boutet ... [et al.] -- Plant database resources at The Institute for Genomic Research / Agnes P. Chan... [et al.] -- MIPS plant genome information resources / Manuel Spannagl ...[et al.] -- HarvEST / Timothy J. Close ... [et al.] -- The TAIR database / Rebecca L. Poole -- AtEnsEMBL / Nick James ... [et al.] -- Accessing integrated Brasica genetic and genomic data using the BASC server / Christopher G. Love and David Edwards -- Leveraging model legume information to find candidate genes for soybean sudden death syndrome using the Legume Information System / Michael D. Gonzales ... [et al.] -- Legume resources : MtDB and Medicago.org / Ernest F. Retzel ... [et al.] -- BGI-RIS V2 / Ximiao He and Jun Wang -- GrainGenes / Helen O'Sullivan -- Gramene / Doreen Ware -- MaizGDB / Carolyn J. Lawrence -- BarleyBase/PLEXdb / Roger P. Wise ... [et al.] -- Reaping the benefits of SAGE / Stephen J. Robinson ... [et al.] -- Methods for analysis of gene expression in plants using MPSS / Kan Nobuta, Kalyan Vemaraju, and Blake C. Meyers -- Metabolomics data analysis, visualization, and integration / Lloyd W. Sumner, Ewa Urbanczyk-Wochniak, and Corey D. Broeckling -- KEGG bioinformatics resource for plant genomics research / Ali Masoudi-Nejad ... [et al.] -- International Crop Information System for germplasms data management / Arllet Portugal ... [et al.] -- Automated discovery of single nucleotide polymorphism and simple sequence repeat molecular genetic markers / Jacqueline Batley, Erica Jewell, and David Edwards -- Methods for gene ontology annotation / Emily Dimmer ... [et al.] -- Gene structure annotation at PlantGDB / Volker Brendel -- An introduction to BioPerl / Jason E. Stajich.
  • 2011 Springer Protocols
    edited by James A. Birchler.
    Recent advances in plant transformation -- Engineering the plastid genome of nicotiana sylvestris, a diploid model species for plastid genetics -- Homologous recombination in plants : An antireview -- Chromosome painting for plant biotechnology -- Plant B chromosomes -- Telomere truncation in plants -- Engineered plant minichromosomes -- Method for bxb1-mediated site-specific integration in planta -- Targeted mutagenesis in arabidopsis using zinc-finger nucleases -- Vectors and methods for hairpin RNA and artificial microRNA-mediated gene silencing in plants -- Recombinant protein expression in nicotiana -- Chromosome analysis and sorting using flow cytometry -- Super-stretched pachytene chromosomes for plant molecular cytogenetic mapping -- Cytological dissection of the triticeae chromosomes by the gametocidal system -- Development and use of oat-maize chromosome additions and radiation hybrids -- Enhancer trapping in plants -- Chromatin beacons : Global sampling of chromatin physical properties using chromatin charting lines -- Transposable elements as catalysts for chromosome rearrangements.
  • 2006 Springer
    edited by S. Dutta Gupta and Yasuomi Ibaraki.
  • 2011 Future Med
    editor, Franco M. Buonaguro.
    Plant-derived vaccines : technologies & applications / Franco M. Buonaguro -- Patents and molecular farming / Pascal M.W. Drake & Harry Thangaraj -- In planta production of recombinant and indigenous adjuvants / Antonio Granell, Asun Fernandez-del-Carmen & Diego Orzáez -- Rapid and high-yield production of immunotherapeutic plant-made antibodies / Cristina Capodicasa, Marcello Donini, Maria Elena Villani & Eugenio Benvenuto -- Vaccine peptide display on recombinant tobacco mosaic virus particles / Tatiana V. Komarova, Igor V. Petrunia & Yuri L. Dorokhov -- Plastid transformation as a tool for plant-based production of vaccines and therapeutic proteins / Paolo Lenzi, Nunzia Scotti, Pal Maliga & Teodoro Cardi -- Prophylactic and therapeutic HPV vaccines from plants / Edward P. Rybicki, Colomba Giorgi & Rosella Franconi -- Plant-derived anti-HIV-1 proteins / Nunzia Scotti, Luigi Buonaguro, Maria Lina Tornesello, Teodoro Cardi & Franco Maria Buonaguro -- Plant-based hepatitis B vaccines / Sergei N. Shchelkunov & Galina A. Shchelkunova -- Influenza vaccines : new perspectives from plants / Chiara Lico, Giampaolo Buriani, Floriana Capuano, Eugenio Benvenuto & Selene Baschieri -- Plant-made mucosal vaccines / Rurick K. Salyaev, Maria Manuela Rigano & Natalya I. Rekoslavskaya -- Current status of plant-made veterinary vaccines / Assunta Pelosi, Claire Penney, Huai-Yian Ling & Amanda M. Walmsley.
  • 2009 Springer
    Alexander V. Karasev, editor.
    Plant vaccines: an immunological perspective / D.C. Hooper -- Display of peptides on the surface of tobacco mosaic virus particles / M.L. Smith ... [et al.] -- Chloroplast-derived vaccine antigens and biopharmaceuticals: expression, folding, assembly and functionality / S. Chebolu and H. Daniell -- Production of antibodies in plants: approaches and perspectives / K. Ko, R. Brodzik and Z. Steplewski -- Plant production of veterinary vaccines and therapeutics / R.W. Hammond and L.G. Nemchinov -- Plant-based oral vaccines: results of human trials / C.O. Tacket.
    Also available: Print – 2009
  • 2005 CRCnetBASE
    [edited by] Severian Dumitriu.
  • 2010 CRCnetBASE
    edited by Taosheng Chen.
  • 2014 ScienceDirect
    edited by Jose Cibelli [and six others].
    Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species-including mice, sheep, cattle, and non-mammals-is considered as well.
  • 2011 ScienceDirect
    2011 ClinicalKey
    [edited by] Anthony Atala ... [et al.].
    Chapter 1. Molecular Organization of Cells / Jon D. Ahlstrom -- Chapter 2. Cell-ECM Interactions in Repair and Regeneration / M. Petreaca, M. Martins-Green -- Chapter 3. Mechanisms of Blastema Formation in Regenerating Amphibian Limbs / David L. Stocum, Nandini Rao -- Chapter 4. The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells and iPS Cells / Harvir Singh, Ali H. Brivanlou -- Chapter 5. How Cells Change their Phenotype / Caroline Beth Sangan, David Tosh -- Chapter 6. Scarless Wound Healing / Allison Nauta, Barrett Larson, Michael T. Longaker, H. Peter Lorenz -- Chapter 7. Somatic Cloning and Epigenetic Reprogramming in Mammals / Heiner Niemann, Wilfried A. Kues, Andrea Lucas-Hahn, Joseph W. Carnwath -- Chapter 8. Engineered Proteins for Controlling Gene Expression / Charles A. Gersbach -- Chapter 9. Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine / Junfeng Ji, Bonan Zhong, Mickie Bhatia -- Chapter 10. Embryonic Stem Cells: Derivation and Properties / Junying Yu, James A. Thomson -- Chapter 11. Alternative Sources of Human Embryonic Stem Cells / Svetlana Gavrilov, Virginia E. Papaioannou, Donald W. Landry -- Chapter 12. Stem Cells from Amniotic Fluid / Mara Cananzi, Anthony Atala, Paolo de Coppi -- Chapter 13. Induced Pluripotent Stem Cells / Keisuke Okita, Shinya Yamanaka -- Chapter 14. MSCs in Regenerative Medicine / Arnold I. Caplan -- Chapter 15. Multipotent Adult Progenitor Cells / Philip Roelandt, Catherine M. Verfaillie -- Chapter 16. Hematopoietic Stem Cell Properties, Markers, and Therapeutics / Kuanyin K. Lin, Grant A. Challen, Margaret A. Goodell -- Chapter 17. Mesenchymal Stem Cells / Zulma Gazit, Gadi Pelled, Dima Sheyn, Nadav Kimelman, Dan Gazit -- Chapter 18. Cell Therapy of Liver Disease: From Hepatocytes to Stem Cells / Stephen C. Strom, Ewa C.S. Ellis -- Chapter 19. Cardiac Stem Cells: Biology and Therapeutic Applications / Sarah Selem, Konstantinos E. Hatzistergos, Joshua M. Hare -- Chapter 20. Skeletal Muscle Stem Cells / Benjamin D. Cosgrove, Helen M. Blau -- Chapter 21. Stem Cells Derived from Fat / Adam J. Katz, Alexander F. Mericli -- Chapter 22. Peripheral Blood Stem Cells / Zhan Wang, Gunter Schuch, J. Koudy Williams, Shay Soker -- Chapter 23. Islet Cell Therapy and Pancreatic Stem Cells / Juan Domínguez-Bendala, Antonello Pileggi, Camillo Ricordi -- Chapter 24. Regenerative Medicine for Diseases of the Retina / Deepak A. Lamba, Thomas A. Reh -- Chapter 25. Somatic Cells: Growth and Expansion Potential of T Lymphocytes / Rita B. Effros -- Chapter 26. Mechanical Determinants of Tissue Development / Jonathan A. Kluge, Gary G. Leisk, David L. Kaplan -- Chapter 27. Morphogenesis of Bone, Morphogenetic Proteins, and Regenerative Medicine / A.H. Reddi -- Chapter 28. Physical Stress as a Factor in Tissue Growth and Remodeling / Joel D. Boerckel, Christopher V. Gemmiti, Yash M. Kolambkar, Blaise D. Porter, Robert E. Guldberg -- Chapter 29. Intelligent Surfaces for Cell-Sheet Engineering / Takanori Iwata, Masayuki Yamato, Teruo Okano -- Chapter 30. Applications of Nanotechnology for Regenerative Medicine / Benjamin S. Harrison, Sirinrath Sirivisoot -- Chapter 31. Design Principles in Biomaterials and Scaffolds / Hyukjin Lee, Hyun Jung Chung, Tae Gwan Park -- Chapter 32. Natural Origin Materials for Bone Tissue Engineering - Properties, Processing, and Performance / V.M. Correlo, J.M. Oliveira, J.F. Mano, N.M. Neves, R.L. Reis -- Chapter 33. Synthetic Polymers / M.C. Hacker, A.G. Mikos -- Chapter 34. Biological Scaffolds for Regenerative Medicine / Alexander Huber, Stephen F. Badylak -- Chapter 35. Hydrogels in Regenerative Medicine / Justin M. Saul, David F. Williams -- Chapter 36. Surface Modification of Biomaterials / Andrés J. García -- Chapter 37. Histogenesis in Three-dimensional Scaffolds / Melissa K. McHale, Nicole M. Bergmann, Jennifer L. West -- Chapter 38. Biocompatibility and Bioresponse to Biomaterials / James M. Anderson -- Chapter 39. Designing Tunable Artificial Matrices for Stem Cell Culture / Elizabeth F. Irwin, Jacob F. Pollock, David V. Schaffer, Kevin E. Healy -- Chapter 40. Biomineralization and Bone Regeneration / Jiang Hu, Xiaohua Liu, Peter X. Ma -- Chapter 41. Cell Therapy for Blood Substitutes / Shi-Jiang Lu, Qiang Feng, Feng Li, Erin A. Kimbrel, Robert Lanza -- Chapter 42. Articular Cartilage / Lily Jeng, Francois Ng kee Kwong, Myron Spector -- Chapter 43. Myoblast Transplantation in Skeletal Muscles / Daniel Skuk, Jacques P. Tremblay -- Chapter 44. Clinical Islet Transplantation / Juliet A. Emamaullee, Michael McCall, A.M. James Shapiro -- Chapter 45. Fetal Tissues / Ryan P. Dorin, Chester J. Koh -- Chapter 46. Engineering of Large Diameter Vessels / Masood A. Machingal, Saami K. Yazdani, George J. Christ -- Chapter 47. Engineering of Small-Diameter Vessels / Brett C. Isenberg, Chrysanthi Williams, Robert T. Tranquillo -- Chapter 48. Cardiac Tissue / Milica Radisic, Michael V. Sefton -- Chapter 49. Regenerative Medicine in the Cornea / May Griffith, Per Fagerholm, Neil Lagali, Malcolm A. Latorre, Joanne Hackett, Heather Sheardown -- Chapter 50. Alimentary Tract / Richard M. Day -- Chapter 51. Extracorporeal Renal Replacement / Kimberly A. Johnston, H. David Humes -- Chapter 52. Tissue Engineering of the Reproductive System / Stefano Da Sacco, Laura Perin, Roger E. De Filippo -- Chapter 53. Cartilage Tissue Engineering / Qiongyu Guo, Jennifer H. Elisseeff -- Chapter 54. Functional Tissue Engineering of Ligament and Tendon Injuries / Savio L.-Y. Woo, Alejandro J. Almarza, Sinan Karaoglu, Rui Liang, Matthew B. Fisher -- Chapter 55. Central Nervous System / Brian G. Ballios, M. Douglas Baumann, Michael J. Cooke, Molly S. Shoichet -- Chapter 56. Peripheral Nerve Regeneration / Mahesh C. Dodla, Vivek J. Mukhatyar, Ravi V. Bellamkonda -- Chapter 57. Tissue Engineering of Skin / Fiona Wood -- Chapter 58. Regenerative Medicine of the Respiratory Tract / Martin A. Birchall, Sam Janes, Paolo Macchiarini -- Chapter 59. The Digit: Engineering of Phalanges and Small Joints / Makoto Komura, Jaehyun Kim, Anthony Atala, James J. Yoo, Sang Jin Lee -- Chapter 60. Intracorporeal Kidney Support / Jae Hyun Bae, Tamer Aboushwareb, Anthony Atala, James J. Yoo -- Chapter 61. Ethical Considerations / Ronald M. Green -- Chapter 62. US Stem Cell Research Policy / Josephine Johnston -- Chapter 63. Overview of the FDA Regulatory Process / Kevin J. Whittlesey, Mark H. Lee, Jiyoung M. Dang, Maegen Colehour, Judith Arcidiacono, Ellen Lazarus, David S. Kaplan, Donald Fink, Charles N. Durfor, Ashok Batra, Stephen L. Hilbert, Deborah Lavoie Grayeski, Richard McFarland, Celia Witten.
  • 2014 ScienceDirect
    edited by Robert Lanza, Robert Langer, Joseph Vacanti.
  • 2007 Springer
    Bob van Hilten (editor), Bart Nuttin (editor).
  • 2007 CRCnetBASE
    edited by Abhinav A. Shukla, Mark R. Etzel, Shishir Gadam.
    Harvest of a therapeutic protein product from high cell density fermentation broths : principles and case study / Elisabeth Russell, Alice Wang, and Anurag S. Rathore -- Expanded bed adsorption for capture from crude solution / Alan Sonnenfeld and Jorg Thommes -- Product recovery by high-gradient magnetic fishing / Matthias Franzreb ... [et al.] -- Protein refolding and scale up / Cynthia Cowgill, Asuman G. Ozturk, and Richard St. John -- Bulk protein crystallization, principles and methods / Mark R. Etzel -- Modes of preparative chromatography / Abhinav A. Shukla and Yinges Yigzaw -- Screening of chromatographic stationary phases / Abhinav A. Shukla and Xuejun Sean Han -- A priori prediction of chromatographic separations from protein structure data / Asif Ladiwala, Curt M. Breneman, and Steven M. Cramer -- Membrane chromatography : analysis of breakthrough curves and viral clearance / Mark R. Etzel and William T. Riordan -- Ultrafiltration process design and implementation / Herb Lutz and Bala Raghunath -- Virus filtration process design and implementation / Michael W. Phillips ... [et al.] -- Product recovery from transgenic sources / Chenming (Mike) Zhang and Kevin E. Van Cott -- Analytical strategy for biopharmaceutical development / Drew N. Kelner and Mahesh K. Bhalgat -- Evaluation of viral clearance in purification processes / Amitava Kundu and Karl Reindel -- Advances in viral clearance / Kurt Brorson -- Protein A affinity chromatography for capture and purification of monoclonal antibodies and Fc-fusion proteins: practical considerations for process development / Sanchayita Ghose, Thomas McNerney, and Brian Hubbard -- Polishing methods for monoclonal IgG purification / Pete Gagnon -- Making changes to a biopharmaceutical manufacturing process during development and commercial manufacturing : the REMICADE story / Peter W. Wojciechowski ... [et al.] -- Linear scale-up of ultrafiltration of high viscosity process streams / Christopher Daniels ... [et al.] -- A membrane chromatography application : a rapid, high capacity gene therapy vector purification tool / Ajay R. Lajmi, Robert Kutner, and Jakob Reiser.
  • 2005 CRCnetBASE
    edited by Anurag Singh Rathore, Gail Sofer.
  • 2007 Springer
    Valentino J. Stella ... [et al.], editors.
  • 2006 CRCnetBASE
    William L. Hochfeld.
  • 2013 Springer
    Eugene Rosenberg (editor-in-chief), Edward F. DeLong...[et al.] (eds.).
    Organic Acid and Solvent Production: Acetic, Lactic, Gluconic, Succinic, and Polyhydroxyalkanoic Acids / Palmer Rogers, Jiann-Shin Chen, Mary Jo Zidwick -- Organic Acid and Solvent Production: Butanol, Acetone, and Isopropanol; 1,3- and 1,2-Propanediol Production; and 2,3-Butanediol Production / Jiann-Shin Chen, Mary Jo Zidwick, Palmer Rogers -- Organic Acid and Solvent Production: Propionic and Butyric Acids and Ethanol / Mary Jo Zidwick, Jiann-Shin Chen, Palmer Rogers -- Amino Acid Production / Hidehiko Kumagai -- Microbial Exopolysaccharides / Avinash Mishra, Dr. Bhavanath Jha -- Bacterial Enzymes / Prof. Wim J. Quax -- Diversity and Biotechnological Applications of Prokaryotic Enzymes / Alane Beatriz Vermelho, Eliane Ferreira Noronha, Edivaldo Ximenes Ferreira Filho -- Bacteria in Food and Beverage Production / Dr. Michael P. Doyle, Larry R. Steenson, Jianghong Meng -- Bacterial Pharmaceutical Products / Giancarlo Lancini, Dr. Arnold L. Demain -- Biosurfactants / Dr. Eugene Rosenberg, Eliora Z. Ron -- Bioremediation / Ronald L. Crawford, Dr. Eugene Rosenberg -- Biodeterioration / Ji-Dong Gu, Ralph Mitchell -- Microbial Biofilms / Dirk De Beer, Paul Stoodley -- Biofuels / Stefano Freguia, Bernardino Virdis, Dr. Korneel Rabaey -- The Metabolic Pathways of Biodegradation / Lawrence P. Wackett.
  • 2013 Springer
    Abdulhameed Sabu, Anu Augustine, editors.
    The book entitled "Prospects in Bioscience: Addressing the issues" is a collection of selected research papers presented at the International Conference on Advances in Biological Sciences (ICABS) organized by the Department of Biotechnology and Microbiology and the Inter University Centre for Bioscience, Kannur University, Kerala, India. ICABS witnessed a unique spectrum of Scientific Programmes on the most recent and exciting developments in modern biology. The conference displayed the numerous breakthroughs and significant developments in the important areas of modern biology and their relevance to the welfare of global society. The Book contains 50 well written chapters, each one discussing scientifically organized findings of original research work done in reputed laboratories. Needless to say, they deal with advances in various disciplines of modern biology including Cell and Molecular Biology, Structural Biology, Industrial and Environmental Biotechnology, Food and Agricultural Biotechnology and Medical Biotechnology. As the title rightly indicates, the chapters project the prospects in the respective areas and the issues in them. Specific issues discussed in the book includes development of transgenic plants, bioremediation of toxic industrial effluents, biotransformation for novel antibiotics, biofertilizer development, molecular drug designing and structure elucidation, molecular identification of pathogens, production of anti microbials, biocontrol agents and bioactive molecules, cancer biology, plant breeding and hybrid seed production etc. The book with its contents spreading across the vast arena of modern biology is expected to cater to the need of researchers, technologists and students.
  • 2014 Springer Protocols
    edited by Nikolaos E. Labrou.
    Protein Purification: An Overview -- Establishment of a Design Space for Biopharmaceutical Purification Processes Using DoE -- High Throughput Process Development: I. Process Chromatography -- High Throughput Process Development: II. Membrane Chromatography -- Media Selection in Ion Exchange Chromatography in a Single Microplate -- High Throughput Screening of Dye-Ligands for Chromatography -- Measurement of Uptake Curves and Adsorption Isotherms by Automated Microscale Chromatography Pipette Tips -- Recovery of Recombinant Proteins from Plants Using Aqueous Two-Phase Partitioning Systems: An Outline -- Aqueous Two-Phase Systems Strategies for the Recovery of Proteins from Plants -- Aqueous Two Phase Assisted Precipitation of Proteins: A Platform for Isolation of Process Related Impurities from Therapeutic Proteins -- Simultaneous Purification and Refolding of Proteins by Affinity Precipitation and Macro-(Affinity Ligand) Facilitated Three Phase Partitioning (MLFTPP) -- Co-Expression and Co-Purification of Antigen-Antibody Complexes in Bacterial Cytoplasm and Periplasm -- Immunoglobulin Purification by Caprylic Acid -- Affinity Tags in Protein Purification and Peptide Enrichment: An Overview -- Expression and Purification of Large Active GST Fusion Enzymes -- Synthetic Ligand Affinity Chromatography. Purification of Human Serum Albumin and Related Fusion Proteins -- Zbasic -- A Purification Tag for Selective Ion-Exchange Recovery -- An Orthogonal Fusion Tag for Efficient Protein Purification -- Phage Display of Engineered Binding Proteins -- Biomimetic Affinity Ligands for Protein Purification -- Synthesis and Application of Dye-Ligand Affinity Adsorbents -- Peptide Affinity Chromatography Based on Combinatorial Strategies for Protein Purification -- Affinity Chromatography of Proteins on Monolithic Columns -- Sample Displacement Batch Chromatography of Proteins -- Analysis of Host-Cell Proteins in Biotherapeutic Proteins by LC/MS Approaches -- Preparation of Monolithic Affinity Media for Nano-Liquid Chromatography Applications -- Proteomic Analysis of Complex Protein Samples by MALDI TOF Mass Spectrometry -- Modern Bioanalysis of Proteins by Electrophoretic Techniques -- Protein Structure Validation and Analysis with X-Ray Crystallography -- Measuring Binding Constants of His-Tagged Proteins using Affinity Chromatography and Ni-NTA Immobilized Enzymes -- Stabilization of Therapeutic Proteins in Aqueous Solutions and Freeze-Dried Solids: An Overview -- Stabilization of Protein by Freeze-Drying in the Presence of Trehalose: A Case Study of Tubulin -- G Protein-Coupled Receptor Expression and Purification.- (Hyper)thermophilic Enzymes: Production and Purification -- Affinity Chromatography for Antibody Purification -- Screening and Purification of Recombinant Lignocellulolytic Enzymes -- Purification of PEGylated Proteins, with the Example of PEGylated lysozyme and PEGylated scFv -- One-Step Purification of Glutamate decarboxylase from E. coli Using Aqueous Two Phase System.
  • 2009 Springer
    Caroline Köhrer, Uttam L. RajBhandary (eds.).
    Understanding enzyme mechanism through protein chimeragenesis / N.M. Goodey and S.J. Benkovic -- Chemical protein engineering : synthetic and semisynthetic peptides and proteins / L. Merkel, L. Moroder, and N. Budisa -- Native chemical ligation: Semisynthesis of post-translationally modified proteins and biological probes / E. Vogel Taylor and B. Imperiali -- Chemical methods for mimicking post-translational modifications / S.I. van Kasteren, P. Garnier and B.G. Davis -- Noncanonical amino acids in protein science and engineering / K.E. Beatty and D.A. Tirrell -- Fidelity mechanisms of the aminoacyl-tRNA synthetases / A.P. Mascarenhas ... [et al.] -- Specialized components of the translational machinery for unnatural amino acid mutagenesis : tRNAs, aminoacyl-tRNA synthetases, and ribosomes / C. Köhrer and U.L. RajBhandary -- In vivo studies of receptors and ion channels with unnatural amino acids / D.A. Dougherty -- Synthesis of modified proteins using misacylated tRNAs / S.M. Hecht -- Cell-free synthesis of proteins with unnatural amino acids. The pure system and expansion of the genetic code / I. Hirao, T. Kanamori and T. Ueda -- Engineering nucleobases and polymerases for an expanded genetic alphabet / A.M. Leconte and F.E. Romesberg -- Understanding membrane proteins. How to design inhibitors of transmembrane protein-protein interactions / J.S. Slusky, H. Yin and W.F. DeGrado.
  • 2013 Springer Protocols
    edited by Ming Zhou and Timothy Veenstra.
    Affinity depletion of plasma and serum for mass spectrometry-based proteome analysis / Julian A.J. Jaros ... [et al.] -- Tissue sample preparation for biomarker discovery / Yoshiyuki Suehara, Daisuke Kubota, and Tsuyoshi Saito -- Subcellular fractionation for identification of biomarkers : serial detergent extraction by subcellular accessibility and solubility / Sun-II Hwang and David K. Han -- Analysis of secreted proteins / Valeria Severino, Annarita Farina, and Angela Chambery -- Preparation of human cerebrospinal fluid for proteomics biomarker analysis / Timothy J. Waybright -- Proteomic analysis of frozen tissue samples using laser capture microdissection / Sumana Mukherjee ... [et al.] -- Use of formalin-fixed, paraffin-embedded tissue for proteomic biomarker discovery / David B. Krizman and Jon Burrows -- Phosphopeptide enrichment using offline titanium dioxide columns for phosphoproteomics / Li-Rong Yu and Timothy Veenstra -- iTRAQ-labeling for biomarker discovery / Leroi V. DeSouza, Sébastien N. Voisin, and K.W. Michael Siu -- Analysis of glycoproteins for biomarker discovery / Jintang He ... [et al.] -- SILAC in biomarker discovery / Benjamin C. Orsburn -- Trypsin-mediated 18O/16O labeling for biomarker discovery / Xiaoying Ye ... [et al.] -- Two-dimensional SDS-PAGE fractionation of biological samples for biomarker discovery / Thierry Rabilloud and Sarah Triboulet -- Informatics of protein and posttranslational modification detection via shotgun proteomics / Jerry D. Holman, Surendra Dasari, and David L. Tabb -- Quantitation of met tyrosine phosphorylation using MRM-MS / Zhaojing Meng -- Preparation of human serum for prolactin measurement by multiple reaction monitoring mass spectrometry / Timothy J. Waybright ... [et al.] -- Label-free quantitative shotgun proteomics using normalized spectral abundance factors / Karlie A. Neilson ... [et al.] -- Employment of complementary dissociation techniques for body fluid characterization and biomarker discovery / David M. Good and Dorothea Rutishauser -- Phosphopeptide microarrays for comparative proteomic profiling of cellular lysates / Liqian Gao ... [et al.] -- Tissue preparation for MALDI-MS imaging of protein and peptides / Simona Colantonio and Roberta M. Smith -- Plant proteogenomics : from protein extraction to improved gene predictions / Brett Chapman ... [et al.] -- Label-free differential analysis of murine postsynaptic densities / Scott P. Goulding, Michael J. MacCoss, and Christine C. Wu -- Fractionation of peptides by strong cation-exchange liquid chromatography / King C. Chan and Haleem J. Issaq.
  • 2013 Springer Protocols
    edited Maurizio Lambardi, Elif Aylin Ozudogru, Shri Mohan Jain.
    Micropropagation of pear (Pyrus sp.) / Barbara M. Reed [and others] -- In vitro propagation of jojoba / Berta E. Llorente and Nancy M. Apóstolo -- In vitro propagation of olive (Olea europaea L.) by nodal segmentation of elongated shoots / Maurizio Lambardi, Elif Aylin Ozudogru, and Romano Roncasaglia -- Micropropagation systems of feijoa (Acca sellowiana (O. Berg) burret) / Miguel Pedro Guerra [and others] -- Micropropagation of Vaccinium sp. by in vitro axillary shoot proliferation / Wojciech Litwinczuk -- In vitro propagation of peanut (Arachis hypogaea L.) by shoot tip culture / Elif Aylin Ozudogru, Ergun Kaya, and Maurizio Lambardi -- In vitro propagation of persimmon (Diospyros kaki Thunb.) / Edgardo Giordani, Mar Naval, and Carla Benelli -- Micropropagation of Citrus spp. by organogenesis and somatic embryogenesis / Benedetta Chiancone and Maria Antonietta Germanà -- Micropropagation of Prunus species relevant to cherry fruit production / Philippe Druart -- Micropropagation of peach rootstocks and cultivars / Ildikó Balla and Lucienne Mansvelt -- Micropropagation of Rubus and Ribes spp / Ewa Dziedzic and Joanna Jagła -- Somatic embryogenesis for efficient micropropagation of guava (Psidium guajava L.) / Nasim Akhtar -- Micropropagation of chokeberry by in vitro axillary shoot proliferation / Wojciech Litwińczuk -- Micropropagation of Lavandula spp / Sandra Gonçalves and Anabela Romano -- In vitro propagation of Acacia mangium and A. mangium? A. auriculiformis / Olivier Monteuuis, Antoine Galiana, and Doreen Goh -- In vitro propagation of ash (Fraxinus excelsior L.) by somatic embryogenesis / Maurizio Capuana -- Micropropagation of paradise tree (Melia azedarach) by in vitro culture of axillary buds / Luis A. Mroginski and Hebe Y. Rey -- In Vitro Propagation of Hydrangea spp / Barbara Ruffoni, Ermanno Sacco, and Marco Savona -- In vitro propagation of fraser photinia using Azospirillum-mediated root development / Berta E. Llorente and Ezequiel E. Larraburu -- Micropropagation of Helleborus through axillary budding / Margherita Beruto, Serena Viglione, and Alessandro Bisignano -- Micropropagation of Cordyline terminalis / Tui Ray, Prasenjit Saha, and Satyesh C. Roy -- Micropropagation of african violet (Saintpaulia ionantha Wendl.) / Mukund Shukla [and others] -- Micropropagation of Iris sp / Sladana Jevremovic, Zoran Jeknic, and Angelina Subotic -- Micropropagation of Gerbera (Gerbera jamesonii Bolus) / Ghani Minerva and Surinder Kumar -- Micropropagation of onion (Allium cepa L.) from immature inflorescences / Pablo Marinangeli -- In vitro propagation of cauliflower using curd microexplants / Martin Kieffer and Michael P. Fuller -- Micropropagation of Asparagus by in vitro shoot culture / Nataša Štajner -- Micropropagation and cryopreservation of garlic (Allium sativum L.) / E.R. Joachim Keller and Angelika Senula -- Micropropagation of globe artichoke (Cynara cardunculus L. var. scolymus) / Giovanni Iapichino -- In vitro rejuvenation of woody species / Paul E. Read and Christina M. Bavougian -- Encapsulation of in vitro- derived explants : an innovative tool for nurseries / Alvaro Standardi and Maurizio Micheli -- Thermotherapy, chemotherapy, and meristem culture in banana / Ludivine Lassois [and others] -- Agrobacterium-mediated genetic transformation of pineapple (Ananas comosus L., Merr.) / Minal Mhatre -- Protocol for inducing flower color somaclonal variation in Torenia (Torenia fournieri Lind.) / Duong Tan Nhut [and others] -- Production of pathogen-free horticultural crops by cryotherapy of in vitro-grown shoot tips / Chaohong Feng [and others].
  • 2008 Springer
    Rosa Margesin ... [et. al.], editors.
  • 2010 Springer
    Antonella Lanati ; in collaborazione con Luigi Cavenaghi ... [et al.] ; presentazione a cura di Marina Del Bue.
  • 2009 HighWire
    International Commission on Radiation Units and Measurements.
  • 2014 Springer Protocols
    edited by Roberto Biassoni, Laboratorio Medicina Molecolare, Dipartimento Medicina Traslazionale, Instituto Giannina Gaslini, Genova, Italy, Alessandro Raso, Laboratorio U.O.C. Neurochirugia, Instituto Giannina Gaslini, Genova, Italy.
    Twenty years of qPCR: A mature technology? -- Minimum information necessary for quantitative real-time PCR experiments -- Selection of reliable reference genes for RT-qPCR analysis -- Introduction to digital PCR -- mRNA and microRNA purity and integrity: The key to success in expression profiling -- Mediator probe PCR: Detection of real-time PCR by label-free probes and a universal fluorogenic reporter -- Absolute quantification of viral DNA: The quest for perfection -- A multiplex real-time PCR-platform integrated into automated extraction method for the rapid detection and measurement of oncogenic HPV type-specific viral DNA load from cervical samples -- Real-time PCR detection of mycoplasma pneumoniae in the diagnosis of community-acquired pneumonia -- A sensible technique to detect mollicutes impurities in human cells cultured in GMP condition -- Real-time quantification assay to monitor BCR-ABL1 transcripts in chronic myeloid leukemia -- A reliable assay for rapidly defining transplacental metastasis using quantitative PCR -- Circulating cell-free DNA in cancer -- Gene expression analysis by qPCR in clinical kidney transplantation -- Posttranscriptional regulatory networks: From expression profiling to integrative analysis of mRNA and microRNA data -- Clinical applications using digital PCR -- Developing noninvasive diagnosis for single-gene disorders: the role of digital PCR.
  • 2014 Springer Protocols
    edited by Adriana Fontes, Beate Saegesser Santos.
  • 2009
    Michael Nathaniel Cantor.
    Status: Not Checked OutLane Catalog Record
  • 2008 ScienceDirect
    Robert M. Rydzewski.
    The drug discovery business to date -- The drug discovery business to come -- Industrial considerations -- how things get done : the project team -- Project considerations -- Hit generation -- Turning hits into drugs -- Initial properties -- ADME and PK properties -- Toxicity related properties -- A career in drug discovery research.
  • 2013 Springer
    Hossein Baharvand, Nasser Aghdami, editors.
    1. Cell Therapy for Neurodegenerative Disorders / Ilyas Singec -- 2. New Prospects for Neural Stem Cell Therapies of Nervous System Diseases Toward the Establishment of Atypical Ectopic Perivascular Stem Cell Niches / Clara Alfaro-Cervello, Chiara Cossetti, Elena Giusto, Matteo Donegà and Stefano Pluchino -- 3. Cultured Limbal Epithelial Stem Cell Therapy for Ocular Surface Diseases / Hannah J. Levis, Julie T. Daniels and Sajjad Ahmad -- 4. Keratinocyte Stem Cells: Biology and Clinical Applications / Carlo Pincelli and Alessandra Marconi -- 5. Cardiac Regeneration with Stem Cells / Beatriz Pelacho, Manuel Mazo, Sheyla Montori, Ana Maria Simon-Yarza, Juan Jose Gavira, Maria J. Blanco-Prieto and Felipe Prósper -- 6. Development of Biological Approaches to Improve Muscle Healing After Injury and Disease / Jonathan D. Proto and Johnny Huard -- 7 Mesenchymal Stem Cells in Bone and Cartilage Regeneration / Mohamadreza Baghaban Eslaminejad, Elham Zomorodian and Fatemeh Bagheri -- 8. Pancreatic Reprogramming / Juan Domínguez-Bendala -- 9. Pancreatic Regeneration in the Face of Diabetes / Zeeshan Ahmad -- 10. Regenerative Therapies for Liver Diseases / Amar Deep Sharma, Ina Rittelmeyer, Tobias Cantz and Michael Ott -- 11. Clinical Studies of Cell Therapy for Liver Cirrhosis / James A. Thomas and Stuart J. Forbes -- 12. Stem Cell Applications for the Treatment of Gastrointestinal System Diseases / Jacobo Trebol Lopez, Tihomir Georgiev-Hristov, Mariano García-Arranz and Damián García-Olmo -- 13. Germ Line Stem Cells: A Promising Alternative Source for Stem-Cell-Based Therapies in Regenerative Medicine / Ellen Goossens and Herman Tournaye -- 14. Cord Blood Stem Cells and Regenerative Medicine / David T. Harris.
  • 2012
    George Church & Ed Regis.
    Status: Not Checked OutLane Catalog Record
    From bioplastics to H. sapiens 2.0 -- -3,800 Myr, Late Hadean : at the inorganic/organic interface -- -3,500 Myr, Archean : reading the most ancient texts and the future of living software -- -500 Myr, Cambrian : the mirror world and the explosion of diversity ; How fast can evolution go and how diverse can it be? -- -360 Myr, Carboniferous : "the best substitute for petroleum is petroleum" -- -60 Myr, Paleocene : emergence of mammalian immune system ; Solving the health care crisis through genome engineering -- -30,000 Yr, Pleistocene Park : engineering extinct genomes -- -10,000 Yr, Neolithic : industrial revolutions ; The agricultural revolution and synthetic genomics ; The BioFab Manifesto -- -100 Yr, Anthropocene : the third industrial revolution ; iGEM -- -1 Yr, Holocene : from personal genomes to immortal human components -- Epigenetic epilogue. +1 Yr, the end of the beginning, transhumanism, and the Panspermia Era : societal risks and countermeasures.
  • 2011 CRCnetBASE
    editors, R.K. Gaur, Yedidya Gafni, P. Sharma, V.K. Gupta.
    "RNA interference (RNAi) is a system within living cells that helps to control active genes and their activity level. Two types of small RNA molecules--microRNA (miRNA) and small interfering RNA (siRNA)--are central to RNA interference. The discovery of RNAi was preceded first by observations of transcriptional inhibition by antisense RNA expressed in transgenic plants and more directly by reports of unexpected outcomes in experiments performed by plant scientists in the U.S. and The Netherlands in the early 1990s. RNAi technology are used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. This book reviews the selective and robust effect of RNAi on gene expression which makes it a valuable research tool, both in cell culture and in living organisms because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. This book will introduce new technology in the study of RNA interference in microorganisms, plants and animals."--Provided by publisher.
  • 2005 Springer
    edited by Trygve Gjedrem.
  • 2015 Springer
    Changming Sun, Tomasz Bednarz, Tuan D. Pham, Pascal Vallotton, Dadong Wang, editors.
    Signal and image analysis techniques are becoming more widely used in biomedical and life science applications. With an emphasis on applications of computational models for solving modern challenging problems in biomedical and life sciences, this book aims to bring collections of articles from biologists, medical/biomedical and health science researchers together with computational scientists to focus on problems at the frontier of biomedical and life sciences. The goals of this book are to build interactions of scientists across several disciplines and to help industrial users apply advanced computational techniques for solving practical biomedical and life science problems. This book is for users in the fields of biomedical and life sciences who wish to keep abreast with the latest techniques in signal and image analysis. The book presents a detailed description to some of the applications. It can be used by those both at graduate and specialist levels.
    Also available: Print – 2015
  • 2012 Springer Protocols
    edited by Debra J. Taxman.
    What parameters to consider and which software tools to use for target selection and molecular design of small interfering RNAs / Olga Matveeva -- Methods for selecting effective siRNA target sequences using a variety of statistical and analytical techniques / Shigeru Takasaki -- Designing functional siRNA with reduced off-target effects / Yuki Naito and Kumiko Ui-Tei -- Design and screening of siRNAs against highly structured RNA targets / Neda Nasheri, John Paul Pezacki, and Selena M. Sagan -- Engineering small interfering RNAs by strategic chemical modification / Jesper B. Bramsen and Jørgen Kjems -- Design, selection, and evaluation of highly specific and functional siRNA incorporating unlocked nucleobase analogs / Narendra Vaish and Pinky Agarwal -- Design, preparation and evaluation of asymmetric small interfering RNA for specific gene silencing in mammalian cells / Chanil Chang [and others] -- Design of nuclease-resistant fork-like small interfering RNA (fsiRNA) / Elena L. Chernolovskaya and Marina A. Zenkova -- Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and MicroRNA-like targeting / Pal Sætrom -- Strategies for designing and Validating immunostimulatory siRNAs / Michael P. Gantier -- Designing efficient and specific endoribonuclease-prepared siRNAs / Vineeth Surendranath [and others] -- Short hairpin RNA-mediated gene silencing / Luke S. Lambeth and Craig A. Smith -- Design of lentivirally expressed siRNAs / Ying Poi Liu and Ben Berkhout -- Bifunctional short hairpin RNA (bi-shRNA) : design and pathway to clinical application / Donald D. Rao [and others] -- Design and chemical modification of synthetic short shRNAs as potent RNAi triggers / Anne Dallas and Brian H. Johnston -- Production and application of long dsRNA in mammalian cells / Katerina Chalupnikova, Jana Nejepinska, and Petr Svoboda -- Design of RNAi reagents for invertebrate model organisms and human disease vectors / Thomas Horn and Michael Boutros -- Construction of shRNA expression plasmids for silkworm cell lines using single-stranded DNA and Bst DNA polymerase / Hiromitsu Tanaka -- Designing effective amiRNA and multimeric amiRNA against plant viruses / Muhammad Fahim and Philip J. Larkin -- Downregulation of plant genes with miRNA-induced gene silencing / Felipe Fenselau de Felippes.
  • 2008 CRCnetBASE
    edited by Igor Galaev, Bo Mattiasson.
  • 2002 CRCnetBASE
    edited by Igor Galaev and Bo Mattiasson.
  • 2008 Springer
    Yanhong Shi, Dennis O. Clegg, editors.
  • 2011 Springer
    Krishnarao Appasani, Raghu K. Appasani, editors ; foreword by Sir John B. Gordon.
    pt. 1. Stem cell biology -- pt. 2. Epigenetic and microRNA regulation in stem cells -- pt. 3. Stem cells for therapeutic applications -- pt. 4. Nuclear reprogramming and induced pluripotent stem cells -- pt. 5. Tissue engineering -- pt. 6. Regenerative medicine.
  • 2012 CRCnetBASE
    edited by Hyunjoon Kong, Andrew J. Putnam, Lawrence B. Schook.
    pt. 1. Defining, isolating, and characterizing various stem and progenitor cell populations for neovascularization -- pt. 2. In vitro studies for angiogenesis, vasculogenesis, and arteriogenesis -- pt. 3. Stem cell mobilization strategies -- pt. 4. Stem cell transplantation strategies.
  • 2014 Springer
    Melvin A. Shiffman, Alberto Di Giuseppe, Franco Bassetto, editors.
    Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed, and the wide range of aesthetic procedures involving stem cell fat transfer are then described in detail. These procedures relate to the face, breast, buttocks, legs, hands, penis, and Poland syndrome. In addition, potential risks and complications are identified. Stem Cells in Aesthetic Procedures: Art, Science, and Clinical Techniques is completely up to date and has been written by leading experts in the field. It will be an invaluable source of information for students, beginners, and experienced surgeons in the fields of plastic surgery, general surgery, cosmetic surgery, facial plastic surgery, otolaryngology, ophthalmology, and oral maxillofacial surgery.
  • 2009 Springer Protocols
    edited by Julie Audet and William L. Stanford.
    Derivation and manipulation of murine embryonic stem cells / Alexander Meissner, Sarah Eminli, and Rudolf Jaenisch -- Patterning mouse and human embryonic stem cells using micro-contact printing / Raheem Peerani ... [et al.] -- Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi / Asmin Tulpule and George Q. Daley -- Measurement of cell-penetrating peptide-mediated transduction of adult hematopoietic stem cells / Aziza P. Manceur and Julie Audet -- Stem cell sources for regenerative medicine / Ali M. Riazi, Sarah Y. Kwon, and William L. Stanford -- Investigating the interactions between haemopoietic stem cells and their niche : methods for the analysis of stem cell homing and distribution within the marrow following transplantation / Brenda Williams and Susan K. Nilsson -- Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells / Valérie Cortin, Nicolas Pineault, and Alain Garnier -- Ex vivo generation of human red blood cells : a new advance in stem cell engineering / Luc Douay and Marie-Catherine Giarratana -- Isolation and manipulation of mammalian neural stem cells in vitro / Claudio Giachino, Onur Basak, and Verdon Taylor -- Isolation, expansion, and differentiation of mouse skin-derived precursors / Karl J.L. Fernandes and Freda D. Miller -- Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord / Hynek Wichterle, Mirza Peljto, and Stephane Nedelec -- Transplantation of neural stem/progenitor cells into developing and adult CNS / Tong Zheng ... [et al.] -- Transplantation of embrynic stem cell-derived dopaminergic neurons in MPTP-treated monkeys / Jun Takahashi, Yasushi Takagi, and Hidemoto Saiki -- Isolation and culture of epithelial stem cells / Jonathan A. Nowak and Elaine Fuchs -- Regeneration of skin and cornea by tissue engineering / Danielle Larouche ... [et al.] -- Prospective isolation of mesenchymal stem cells from mouse compact bone / Brenton J. Short, Nathalie Brouard, and Paul J. Simmons -- Isolation, propagation, and characterization of human umbilical cord perivascular cells (HUCPVCs) / Rahul Sarugaser ... [et al.] -- Bone marrow-derived mesenchymal stem cells : isolation, expansion, characterization, viral transduction, and production of conditioned medium / Massimilano Gnecchi and Luis G. Melo -- Template DNA-strand co-segregation and asymmetric cell division in skeletal muscle stem cells / Vasily Shinin, Barbara Gayraud-Morel, and Shahragim Tajbakhsh -- Isolation and grafting of single muscle fibres / Charlotte A. Collins and Peter S. Zammit -- Differentiation and dynamic analysis of primitive vessels from embryonic stem cells / Gefei Zeng and Victoria L. Bautch -- Derivation of contractile smooth muscle cells from embryonic stem cells / Sanjay Sinha, Mark H. Hoofnagle, and Gary K. Owens -- Islet-derived progenitors as a source of in vitro islet regeneration / Stephen Hanley and Lawrence Rosenberg -- Isolation and characterization of hepatic stem cells, or "oval cells," from rat livers / Thomas D. Shupe ... [et al.] -- Reprogramming of liver to pancreas / Shifaan Thowfeequ ... [et al.]
  • 2009 Atypon
    Binseng Wang.
    Technology is essential to the delivery of health care but it is still only a tool that needs to be deployed wisely to ensure beneficial outcomes at reasonable costs. Among various categories of health technology, medical equipment has the unique distinction of requiring both high initial investments and costly maintenance during its entire useful life. This characteristic does not, however, imply that medical equipment is more costly than other categories, provided that it is managed properly. The foundation of a sound technology management process is the planning and acquisition of equipment, collectively called technology incorporation. This lecture presents a rational, strategic process for technology incorporation based on experience, some successful and many unsuccessful, accumulated in industrialized and developing countries over the last three decades. The planning step is focused on establishing a Technology Incorporation Plan (TIP) using data collected from an audit of existing technology, evaluating needs, impacts, costs, and benefits, and consolidating the information collected for decision making. The acquisition step implements TIP by selecting equipment based on technical, regulatory, financial, and supplier considerations, and procuring it using one of the multiple forms of purchasing or agreements with suppliers. This incorporation process is generic enough to be used, with suitable adaptations, for a wide variety of health organizations with different sizes and acuity levels, ranging from health clinics to community hospitals to major teaching hospitals and even to entire health systems. Such a broadly applicable process is possible because it is based on a conceptual framework composed of in-depth analysis of the basic principles that govern each stage of technology lifecycle. Using this incorporation process, successful TIPs have been created and implemented, thereby contributing to the improvement of healthcare services and limiting the associated expenses.
  • 2015 Knovel
    edited by Marcos Luciano Bruschi.
  • 2013 Springer Protocols
    edited by Karen M. Polizzi, Cleo Kontoravdi.
    In Synthetic Biology , expert researchers in the field provide the latest developments in molecular biology techniques used in Synthetic Biology. Focusing on computational tools that will aid in systematising the design and construction of parts and systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Synthetic Biology seeks to aid scientists in the further study of developing new biological components and systems.
  • 2009 Springer
    Markus Schmidt ... [et al.], editors.
    Introduction / Markus Schmidt -- That Was the Synthetic Biology That Was / Luis Campos -- An Introduction to Synthetic Biology / Carolyn M.C. Lam, Miguel Godinho and Vítor A.P. Martins dos Santos -- Computational Design in Synthetic Biology / Maria Suarez, Guillermo Rodrigo, Javier Carrera and Alfonso Jaramillo -- The Ethics of Synthetic Biology: Outlining the Agenda / Anna Deplazes, Agomoni Ganguli-Mitra and Nikola Biller-Andorno -- Do I Understand What I Can Create? Biosafety Issues in Synthetic Biology / Markus Schmidt -- Security Issues Related to Synthetic Biology Between Threat Perceptions and Governance Options / Alexander Kelle -- The Intellectual Commons and Property in Synthetic Biology / Kenneth A. Oye and Rachel Wellhausen -- Governing Synthetic Biology: Processes and Outcomes / Joyce Tait -- Synthetic Biology and the Role of Civil Society Organizations Shaping the Agenda and Arena of the Public Debate / Dirk Stemerding, Huib de Vriend, Bart Walhout and Rinie van Est -- Summary and Conclusions / Alexander Kelle.
  • 2013 ScienceDirect
    edited by Huimin Zhao.
    Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms. Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomesHighlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications. Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development.
  • 2009 Springer
    Sang Yup Lee, editor.
  • 2012 Springer
    Aleš Prokop, Seth Michelson.
  • 2012 Springer
    Asfar S. Azmi, editor.
    Part I. Systems biology in cancer -- Part II. Systems approaches to understand cancer progression -- Part III. Systems and network biology in decoding miRNA complexity -- Part IV. Network modeling in cancer drug discovery and clinical trials.
  • 2010 ScienceDirect
    edited by Edison T. Liu and Douglas A. Lauffenburger.
  • 2012 Springer
    Christoph Wittmann, Sang Yup Lee, editors.
    Preface / Christoph Wittmann and Sang Yup Lee -- 1. Genome-scale network modeling / Sang Yup Lee, Seung Bum Sohn, Hyun Uk Kim, Jong Myoung Park, Tae Yong Kim, Jeffrey D. Orth, and Bernhard Ø. Palsson -- 2. Kinetic modeling of metabolic networks / Daniel C. Zielinski and Bernhard Ø. Palsson -- 3. Design of superior cell factories based on systems wide omics analysis / Katsunori Yoshikawa, Chikara Furusawa, Takashi Hirasawa, and Hiroshi Shimizu -- 4. Technologies for bio-systems engineering / Sonja Billerbeck, Sven Dietz, Gaspar Morgado, and Sven Panke -- 5. Systems metabolic engineering of Escherichia coli for chemicals, materials, biofuels, and pharmaceuticals / Dokyun Na, Jin Hwan Park, Yu-Sin Jang, Jeong Wook Lee, and Sang Yup Lee -- 6. Systems metabolic engineering of Corynebacterium glutamicum for biobased production of chemicals, materials and fuels / Judith Becker, Stefanie Kind, and Christoph Wittmann -- 7. Towards a synthetic biology of the stress-response and the tolerance phenotype: systems understanding and engineering of the Clostridium acetobutylicum stress-response and tolerance to toxic metabolites / Eleftherios T. Papoutsakis and Keith V. Alsaker -- 8. Model-based design of superior cell factory: an illustrative example of Penicillium chrysogenum / I. Emrah Nikerel, Peter J.T. Verheijen, Walter M. van Gulik, and Joseph J. Heijnen -- 9. Bridging omics technologies with synthetic biology in yeast industrial biotechnology / António Roldão, Il-Kwon Kim, and Jens Nielsen -- 10. Design of superior cell factories for a sustainable biorefinery by synthetic bioengineering / Tomohisa Hasunuma, Fumio Matsuda, and Akihiko Kondo -- 11. Systems-level analysis of cancer metabolism / Paulo A. Gameiro, Christian M. Metallo, and Gregory Stephanopoulos.
  • 2011 CRCnetBASE
    editors, R.M. Natal Jorge, João Manuel R.S. Tavares, Marcos Pinotti Barbosa, Alan Peter Slade.
  • 2010 Springer
    Dennis R. Cooley.
    Applied groundwork for a practical moral code. Introduction ; Definitions ; Professional moral codes ; USDA study : methodology and results ; Formalization and evaluation of the USDA study's moral codes ; Formalization of the combination moral code ; Problems for the combination moral code ; Conclusion -- A practical moral code. Introduction ; Utilitarianism ; What is a reasonable person? ; RPU's benefits ; Respecting persons ; Working toward a plausible distributive/social justice principle ; The moral paradigm test ; Conclusion -- Are transgenic organisms, biotechnology, and technology unnatural? Introduction ; The unnatural is unethical argument ; The weak definitions ; A "playing God" argument ; More complex meanings of the unnatural ; Arguments from evolution ; Conclusion -- A natural theory of value. Introduction ; Naturalness as sacredness ; Beginning an axiology ; The benefit of the doubt principle ; Intrinsically valuable things and their rankings ; Is nature or the biosphere alive? ; Arguments against nature's intrinsic value ; Conclusion -- Applying PMC to a few transgenic technology issues. Introduction ; The practical moral code again ; Transgenics and RPU ; Transgenics and QCI ; Legal/moral questions ; Conclusion.
  • 2013 Springer
    Philippe A. Liverneaux, Stacey H. Berner, Michael S. Bednar, Sijo J. Parekattil, Gustavo Mantovani Ruggiero, Jesse C. Selber, editors.
    Part 1. GENERAL -- History of Microsurgery / Yoshikazu Ikuta -- History of Telesurgery / James Wall and Jacques Marescaux -- Description of Robots / Jesse Creed Selber -- Instruments / Sijo Joseph Parekatti and Michael Moran -- Robot Installation in Telemicrosurgery / Thierry Lequint, Kiyohito Naito, Eric Nectoux, Sybille Facca and Philippe Liverneaux -- Part 2. TRAINING -- Earthworms / Gustavo Mantovani Ruggiero -- Vessels / Joo-Yup Lee and Alexander Y. Shin -- Nerves / Stacey H. Berner -- Part 3. EXPERIMENTAL RESEARCH -- Free Tissue Transfer / Stacey H. Berner -- Tele-endomicrosurgery / Sybille Facca, Kiyohito Naito, Thierry Lequint, Eric Nectoux and Philippe Liverneaux -- Brachial Plexus Repair / Gustavo Mantovani Ruggiero and Philippe Liverneaux -- Tendon Transfer / Michael S. Bednar -- Part 4. CLINICAL APPLICATIONS -- Nerve Entrapment / Jose Carlos Garcia Jr. -- Nerve Repair / Stacey H. Berner -- Brachial Plexus / Kiyohito Naito, Mickaël Ohana, Thierry Lequint, Sybille Facca and Philippe Liverneaux -- Skin Flaps / Thomas Lauwers, Tom Van Mulken and Darren Booi -- Muscle Flaps / Jesse Creed Selber and John C. Pedersen -- Head and Neck / Jesse Creed Selber -- Urology / Sijo Joseph Parekattil -- Part 5. PERSPECTIVES -- Supermicrosurgery / Takeshi Todokoro and Isao Koshima -- Network / Catherine Jane Mohr.
  • 2007 Springer
    Hermann Scharfetter, Robert Merwa (eds.).
  • 2010 Springer
    edited by José Luis Pedraz, Gorka Orive.
    Highlights and trends in cell encapsulation / Gorka Orive and José Luis Pedraz -- Biomaterials in cell microencapsulation / Edorta Santos ... [et al.] -- Development of subsieve size capsules and application to cell therapy / Shinji Sakai and Koei Kawakami -- Regulatory considerations in application of encapsulated cell therapies / J. van Zanten and Paul de Vos -- Treatment of diabetes with encapsulated islets / Paul de Vos, Milica Spasojevic, and Marijke M. Faas -- Epo delivery by genetically engineered C2C12 myoblasts immobilized in microcapsules / Ainhoa Murua ... [et al.] -- Artificial cell microencapsulated stem cells in regenerative medicine, tissue engineering, and cell therapy / Zun Chang Liu and Thomas Ming Swi Chang -- Microencapsulated choroid plexus epithelial cell transplants for repair of the brain / Christopher G. Thanos, Briannan Bintz, and Dwaine F. Emerich -- Therapeutic application of cell microencapsulation in cancer / Brian Salmons and Walter H. Gunzburg -- Inorganic nanoporous membranes for immunoisolated cell-based drug delivery / Adam Mendelsohn and Tejal Desai -- Cell microencapsulation / Grace J. Lim ... [et al.] -- Commercial applicability of cell microancapsulation : a review of intellectual property rights / Stephan M. Meier.
    Also available: Print – 2010
  • 2011 Springer
    Norbert Pallua, Christoph V. Suschek, editors.
    BASICS AND PRINCIPLES: Scaffolds: Micro and Nano Technology -- Biomimetic Materials -- Natural and Synthetic Scaffolds: Adhesion, ECM, Structure, Function, Modification -- Cells: Sources, Growth, Differentiation, Trans-Differentiation -- Embryonic Stem Cells: Sources and Characterization -- Adult Stem Cells: Sources and Characterization -- Isolation and Growth -- Differentiation and Plasticity -- Regulation Mechanisms: Key Signaling Molecules -- Cell and Organ preservation -- Engineering Technologies: Animal Models for Evaluation of Tissue Engineering Constructs -- Biomedical Imaging and Image Processing -- Bioreactors for Tissue Engineering -- Drug delivery -- Gene Therapy -- OROGANS: Liver -- Musculoskeletal Tissues -- Lung -- CNS -- Peripheral Nervous System -- Nephrons -- Biohybrid organs -- Heart and Cardiovascular Engineering -- Eye/Retina -- Respiratory Systems Engineering -- Ear -- Skin -- TISSUE TYPES: Adipose Tissue -- Blood Substitutes -- Angiogenesis and Vascularization -- Bone Tissue -- Brain Tissues -- Cartilage Tissue -- Pancreatic Tissues -- Tendons -- Tissue Engineering in Reproductive Medicine, of Heart Valves, in Oral and Maxillofacial Surgery -- Uro-Gital System/Bladder Tissue.
  • 2006 ScienceDirect
    SU Catalog (SearchWorks) Click LINK above for Print location/circulation status.
    Yoshito Ikada.
  • 2013 CRCnetBASE
    edited by Murugan Ramalingam, Pekka Vallittu, Ugo Ripamonti and Wan-Ju Li.
    "This book bridges the gap between nanotechnology and regenerative medicine to facilitate their transition from lab to the clinic. It compiles important aspects of the basic science and fundamental principles to current nanotechnological innovations in biomaterials, cell, tissue, and organ engineering, and their clinical relevance, as well as future trends in regenerative medicine. It is intended for a wide audience including students, researchers, professors, and industrial experts working in the tields of biomaterial science and engineering, nanoscience and nanotechnology, bioengineering, cell biology, biomedical sciences, tissue engineering, and nanomedicine"--Provided by publisher.
  • 2011 Springer
    Harold S. Bernstein, editor.
    pt. 1. Stem cells -- pt. 2. Biomaterials and the extracellular environment -- pt. 3. Engineered tissue -- pt. 4. Synthetic organs -- pt. 5. Immune response -- pt. 6. Animal models.
  • 2010 Springer Protocols
    edited by Ronald Simon.
    Applications of tissue microarray technology -- Quality aspects of TMA analysis -- Representativity of TMA studies -- Recipient block TMA technique -- Protocol for constructing tissue arrays by cutting edge matrix assembly -- Hypodermic needle without recipient paraffin block technique -- Resin technologies : construction and staining of resin TMA's -- Tissue microarrays from frozen tissues-OCT technique -- An alternative technology to prepare tissue microarray using frozen tissue samples -- Building "tissue" microarrays from suspension cells -- Tissue microarrays from biopsy specimens -- Immunohistochemical analysis of tissue microarrays -- DNA copy number analysis on formalin-fixed paraffin-embedded tissues in TMA format by RNA in situ hybridization -- Automated analysis of tissue microarrays -- Digital microscopy for boosting database integration and analysis in TMA studies -- From gene to clinic : TMA-based clinical validation of molecular markers in prostate cancer
  • 2007
    edited by Rosa León, Aurora Gaván, Emilio Fernández.
    In the grip of algal genomics / Arthur R. Grossman -- Insertional mutagenesis as a tool to study genes/functions in chlamydomonas / Aurora Gaván, David González-Ballester, and Emilio Fernández -- Optimization of recombinant protein expression in the chloroplasts of green algae / Samuel P. Fletcher, Machiko Muto, and Stephen P. Mayfield -- Nuclear transformation of eukaryotic microalgae : historical overview, achievements, and problems / Rosa León and Emilio Fernández -- Transformation of cyanobacteria / Agustín Vioque -- Molecular biology and the biotechnological potential of diatoms / Peter Kroth -- Tools and techniques for chloroplast transformation of chlamydomonas / Saul Purton -- Phycoremediation of heavy metals using transgenic microalgae / Sathish Rajamani ... [et al.] -- Hydrogen fuel production by transgenic microalgae / Anastasios Melis, Michael Seibert, and Maria L. Ghirardi -- Microalgal vaccines / Surasak Siripornadulsil, Konrad Dabrowski, and Richard Sayre.
  • 2009 Springer
    Hossein Baharvand, editor.
  • 2014 Springer
    edited by Steven Kanner.
  • 2012 Springer Protocols
    edited by Bernhard Suter, Erich E. Wanker.
    Matrix-based yeast two-hybrid screen strategies and comparison of systems / Roman Häuser [and others] -- Array-based yeast two-hybrid screens : a practical guide / Roman Häuser [and others] -- High-throughput yeast two-hybrid screening / George G. Roberts III [and others] -- A stringent yeast two-hybrid matrix screening approach for protein-protein interaction discovery / Josephine M. Worseck [and others] -- High-throughput yeast two-hybrid screening of complex cDNA libraries / Kerstin Mohr and Manfred Koegl -- Virus-human cell interactomes / Lionel Tafforeau, Chantal Rabourdin-Combe, and Vincent Lotteau -- Interactome mapping in malaria parasites : challenges and opportunities / Douglas J. LaCount -- Mapping interactomes with high coverage and efficiency using the shifted transversal design / Xiaofeng Xin, Charles Boone, and Nicolas Thierry-Mieg -- Assigning confidence scores to protein-protein interactions / Jingkai Yu, Thilakam Murali, and Russell L. Finley Jr. -- The integration and annotation of the human interactome in the UniHI database / Gautam Chaurasia and Matthias Futschik -- Gene-centered yeast one-hybrid assays / John S. Reece-Hoyes and Albertha J.M. Walhout -- One- plus two-hybrid system for the efficient selection of missense mutant alleles defective in protein-protein interactions / Ji Young Kim, Ok Gu Park, and Young Chul Lee -- Investigation of membrane protein interactions using the split-ubiquitin membrane yeast two-hybrid system / Julia Petschnigg [and others] -- Application of the split-protein sensor trp1 to protein interaction discovery in the yeast Saccharomyces cerevisiae / Mandana Rezwan [and others] -- Tetracycline repressor-based mammalian two-hybrid systems / Kathryn Moncivais and Zhiwen Jonathan Zhang -- The fluorescent two-hybrid (F2H) assay for direct analysis of protein-protein interactions in living cells / Kourosh Zolghadr, Ulrich Rothbauer, and Heinrich Leonhardt -- ArrayMAPPIT : a screening platform for human protein interactome analysis / Sam Lievens [and others] -- MAPPIT as a high-throughput screening assay for modulators of protein-protein interactions in HIV and HCV / Bertrand Van Schoubroeck [and others] -- Integrated measurement of split TEV and cis-regulatory assays using EXT encoded reporter libraries / Anna Botvinik and Moritz J. Rossner.
  • 2007 Springer
    Boris Bogdan, Ralph Villiger ; [with a foreword by Steve Burrill].
  • 2008 Springer
    Boris Bogdan, Ralph Villiger.
  • 2011 CRCnetBASE
    Nicole F. Steinmetz, Marianne Manchester.
    Ch. 1. An introduction to VNPs and nanotechnology -- ch. 2. Overview of the manifold VNPs used in nanotechnology -- ch. 3. Production of VNPs, VLPs, and chimeras -- ch. 4. The art of bioconjugation : functionalization of VNPs -- ch. 5. Encapsulating materials within VNPs -- ch. 6. VNPs as templates for materials synthesis -- ch. 7. Playing "nano-lego" : VNPs as building blocks for the construction of multi-dimensional arrays -- ch. 8. VNPs as tools for nanomedicine -- ch. 9. Summary and outlook.
  • 2012
    Adam Richard Sciambi.
    Two dimensional electron systems (2DESs) at semiconductor interfaces are a useful medium for studying complex physics due to their very low disorder and relative simplicity. Many interesting effects, such as the quantum Hall effect, have been discovered through transport measurements in such systems. Unfortunately, the interfacial nature of 2DESs and the related surface energy barrier means that directly accessing them from the surface is difficult. This has limited our understanding of theoretically-predicted, spatially-organized effects such Wigner-crystal microemulsions and quantum Hall stripes, which have been probed only indirectly. In this dissertation, we develop a new type of local probe that circumvents the surface barrier by tunneling into a 2DES from a second 2DES grown nearby. The interlayer tunneling happens directly below a scanned metal tip outside the sample, behaving as a virtual tip in a system we call Virtual Scanning Tunneling Microscopy (VSTM). In the first half of the dissertation, we discuss a novel mechanism for tuning tunneling locally between two 2DESs. Its premise is that raising a quantum potential well next to an adjacent barrier is energetically similar to lowering the barrier relative to a fixed well. A lower barrier leads to the quantum well wave function extending into it and to increased tunneling into a second quantum well on the opposite side. We characterize this mechanism in a GaAs-AlGaAs heterostructure as a new type of transistor. In the second half of the dissertation, results from a working VSTM system are presented, with local interlayer tunneling revealing hidden features in the interfaces below the surface.
  • 2014 Springer Protocols
    edited by Baochuan Lin and Banahalli Ratna.
    Genetic engineering and chemical conjugation of potato virus X / Karin L. Lee, Kerstin [and four others] -- Genetically engineering adenoviral vectors for gene therapy / Lynda Coughlan - Simulated digestion for testing the stability of edible vaccine based on Cucumber mosaic virus (CMV) chimeric particle display Hepatitis C virus (HCV) peptide / Antonella Vitti [and three others] -- Using phage as a platform to select cancer cell-targeting peptides / Xin Li and Chuanbin Mao -- Bacteriophage T4 capsid packaging and unpackaging of DNA and proteins / Julienne M. Mullaney and Lindsay W. Black -- Templated mineralization by charge-modified cowpea mosaic virus / Alaa A.A. Aljabali and David J. Evans -- Polyelectrolyte-modified cowpea mosaic virus for the synthesis of gold nanoparticles / Alaa A.A. Aljabali and David J. Evans -- Tobacco mosaic virus capsid protein as targets for the self-assembly of gold nanoparticles / Omar K. Zahr and Amy Szuchmacher Blum -- Tobacco mosaic virus assembled high aspect ratio surfaces / Adam D. Brown and James N. Culver -- Phage as a template to grow bone mineral nanocrystals / Binrui Cao, Hong Xu, and Chuanbin Mao -- Genetic engineering and characterization of cowpea mosaic virus empty virus-like particles / Frank Sainsbury [and five others] -- A programmable fluorescent viral nanoblock : sensing made easy in a single step / Carissa M. Soto -- Chemical modification of the inner and outer surfaces of tobacco mosaic virus (TMV) / Michael A. Bruckman and Nicole F. Steinmetz -- Engineered bacteriophage T4 nanoparticles for cellular imaging / Jinny L. Liu and Kelly L. Robertson -- Phage-displayed single domain antibodies as recognition elements / Ellen Goldman and Scott Walper -- Molecular targeted viral nanoparticles as tools for imaging cancer / Choi-Fong Cho [and five others].
  • 2009 Springer
    Marianne Manchester, Nicole F. Steinmetz, editors.
    Chemical modification of viruses and virus-like particles / E. Strable, M.G. Finn -- Structure-based engineering of an icosahedral virus for nanomedicine and nanotechnology / N.F. Steinmetz, T. Lin, G.P. Lomonossoff, J.E. Johnson -- Hybrid assembly of CPMV viruses and surface characteristics of different mutants / N.G. Portney, G. Destito, M. Manchester, M. Ozkan -- A library of protein cage architectures as nanomaterials / M.L. Flenniken ... [et al.] -- Biomedical nanotechnology using virus-based nanoparticles / G. Destito, A. Schneemann, M. Manchester -- Tumor targeting using canine parvovirus nanoparticles / P. Singh.
    Also available: Print – 2009
  • 2002 Knovel
  • 2008 Springer
    edited by Francesca Molfino, Flavia Zucco.
  • 2014 Springer Protocols
    edited by Valeria Mapelli, Industrial Biotechnology, Chalmers University of Technology, Gothenbug, Sweden.
    An overview on selection marker genes for transformation of Saccharomyces cerevisiae -- Natural and modified promoters for tailored metabolic engineering of the yeast Saccharomyces cerevisiae -- Tools for genetic engineering of the yeast Hansenula polymorpha -- Molecular tools and protocols for engineering the acid-tolerant yeast Zygosaccharomyces bailii as a potential cell factory -- Strains and molecular tools for recombinant protein production in Pichia pastoris -- Methods for efficient high-throughput screening of protein expression in recombinant pichia pastoris strains -- Synthetic RNA switches for yeast metabolic engineering: Screening recombinant enzyme libraries -- Generation of arming yeasts with active proteins and peptides via cell surface display system: Cell surface engineering, bio-arming technology -- Genetic engineering of industrial Saccharomyces cerevisiae strains using a selection/counter-selection approach -- Evolutionary engineering of yeast -- Determination of a dynamic feeding strategy for recombinant pichia pastoris strains -- Yeast metabolomics: Sample preparation for a GC/MS based analysis -- 13CC-based metabolic flux analysis in yeast: The Pichia pastoris case -- Pathway activity profiling (PAPi): A tool for metabolic pathway analysis -- QTL mapping by pooled-segregant whole-genome sequencing in yeast -- Genome-scale metabolic models of yeast, methods for their reconstruction, and other applications -- Model-guided identification of gene deletion targets for metabolic engineering in Saccharomyces cerevisiae -- Patents: A tool to bring innovation from the lab bench to the marketplace.
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