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Biotechnology

  • NCBI Bookshelf
    This searchable database is a collection of in vivo molecular imaging agents developed for positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), ultrasound (US), computed tomography (CT), and optical imaging. MICAD, a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, is being developed by NCBI, the National Center for Biotechnology Information".
  • 2010 CRCnetBASE
    Karl Fraser, Zidong Wang, Xiaohui Liu.
  • 2014 CRCnetBASE
    edited by Luis Rueda.
    Microarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of microarrays, the book:Describes the key stages of image processing, gridding, segmentation, compression, quantification, and normalizationFeatures cutting-edge approaches to clustering, biclustering, and the reconstruction of regulatory networksCovers different ty.
  • 2005 Springer
    U.R. Müller, D.V. Nicolau (eds.).
    pt. 1. General microarray technologies -- pt. 2. DNA microarrays -- pt. 3. Protein microarrays -- pt. 4. Cell & tissue microarrays.
  • 2008 Springer
    Andreas Bosio, Bernhard Gerstmayer, editors.
    Also available: Print – 2008
  • 2012 Springer Protocols
    edited by José-Luis Barredo.
  • 2003 CRCnetBASE
    Eric R. Lee.
  • 2013 Springer Protocols
    edited by Gareth Jenkins, Colin D. Mansfield.
    Present technology and future trends in point-of-care microfluidic diagnostics / Lawrence Kulinsky, Zahra Noroozi, and Marc Madou -- Teaching microfluidic diagnostics using Jell-O® chips / Cheng Wei T. Yang and Eric T. Lagally -- Fundamentals of microfluidics for high school students with no prior knowledge of fluid mechanics / Vishal Tandon and Walter Peck -- Measuring microchannel electroosmotic mobility and zeta potential by the current monitoring method / Chenren Shao and Don L. DeVoe -- Overview of the microfluidic diagnostics commercial landscape / Lily Kim -- Practical aspects of the preparation and filing of patent applications / Fiona Bessoth -- Introduction to in vitro diagnostic device regulatory requirements / Jonathan Day -- Microfluidic device fabrication by thermoplastic hot-embossing / Shuang Yang and Don L. DeVoe -- Introduction to glass microstructuring techniques / Radoslaw Mazurczyk and Colin D. Mansfield -- Glass microstructure capping and bonding techniques / Radoslaw Mazurczyk, Colin D. Mansfield, and Marcin Lygan -- Rapid prototyping of PDMS devices using SU-8 lithography / Gareth Jenkins -- Microfluidic interface technology based on stereolithography for glass-based lab-on-a-chips / Song-I Han and Ki-Ho Han -- Three-dimensional, paper-based microfluidic devices containing internal timers for running time-based diagnostic assays / Scott T. Phillips and Nicole K. Thom -- Thread based devices for low-cost diagnostics / Meital Reches -- Droplet-based microfluidics / Sanjiv Sharma [and others] -- Droplet-based microfluidics for binding assays and kinetics based on FRET / Monpichar Srisa-Art and Sanjiv Sharma -- Surface treatments for microfluidic biocompatibility / N.J. Shirtcliffe, R. Toon, and P. Roach -- Superhydrophobicity for antifouling microfluidic surfaces / N.J. Shirtcliffe and P. Roach -- Application of microfluidic devices for viral diagnosis in developing countries / Samantha M. Hattersley, John Greenman, and Stephen J. Haswell -- Applications of microfluidics for molecular diagnostics / Harikrishnan Jayamohan, Himanshu J. Sant, and Bruce K. Gale -- Quantitative heterogeneous immunoassays in protein modified polydimethylsiloxane microfluidic channels for rapid detection of disease biomarkers / Peng Li -- Breast cancer diagnostics using microfluidic multiplexed immunohistochemistry / Minseok S. Kim, Seyong Kwon, and Je-Kyun Park -- Charged-coupled device (CCD) detectors for lab-on-a chip (LOC) optical analysis / Avraham Rasooly, Yordan Kostov, and Hugh A. Bruck -- Multilayer microfluidic poly(ethylene glycol) diacrylate hydrogels / Michael P. Cuchiara and Jennifer L. West -- Purification of DNA/RNA in a microfluidic device / Andy Fan, Samantha Byrnes, and Catherine Klapperich -- Agarose droplet microfluidics for highly parallel and efficient single molecule emulsion PCR / Xuefei Leng and Chaoyong James Yang -- Integrated fluidic circuits (IFCs) for digital PCR / Ramesh Ramakrishnan [and others] -- microFIND® approach to fluorescent in situ hybridization (FISH) / Andrea Zanardi, Emanuele Barborini, and Roberta Carbone -- ELISA lab-on-a-chip (ELISA-LOC) / Avraham Rasooly, Hugh A. Bruck, and Yordan Kostov -- Multiplexed surface plasmon resonance imaging for protein biomarker analysis / Eric Ouellet, Louise Lund, and Eric T. Lagally -- Surface acoustic wave (SAW) biosensors : coupling of sensing layers and measurement / Kerstin Lange, Friederike J. Gruhl, and Michael Rapp -- Microchip UV absorbance detection applied to isoelectric focusing of proteins / Junjie Ou and Carolyn L. Ren.
  • 2006 CRCnetBASE
    Paul C.H. Li.
  • 2009 Springer Protocols
    edited by David J. Carroll.
    Expression of exogenous mRNA in Xenopus laevis embryos for the study of cell cycle regulation / Jill C. Sible and Brian N. Wroble -- Use of luciferase chimaera to monitor PLC[zeta] expression in mouse eggs / Karl Swann ... [et al.] -- Analysis of 14-3-3 family member function in Xenopus embryos by microinjection of antisense morpholino oligos / Jeffrey M.S. Lau and Anthony J. Muslin -- A microinjectable biological system, the Xenopus oocyte, as an approach to understanding signal transduction protein function / Katia Cailliau and Edith Browaeys-Poly -- Combining microinjection and immunoblotting to analyse MAP kinase phosphorylation in single starfish oocytes and eggs / David J. Carroll and Wei Hua -- Analysis of signaling pathways in zebrafish development by microinjection / William H. Kinsey -- Protein inhibition by microinjection and RNA-mediated interference in tissue culture cells : complementary approaches to study protein function / Jane R. Stout, Rania S. Rizk, and Claire E. Walczak -- DNA delivery by microinjection for the generation of recombinant mammalian cell lines / Sebastien Chenuet ... [et al.] -- Bacteriophage [phi]C31 integrase mediated transgenesis in Xenopus laevis for protein expression at endogenous levels / Bryan G. Allen and Daniel L. Weeks -- Germline transformation of Caenorhabditis elegans by injection / Pavan Kadandale, Indrani Chatterjee, and Andrew Singson -- Quantitative microinjection of mouse oocytes and eggs / Douglas Kline -- Microinjection of follicle-enclosed mouse oocytes / Laurinda A. Jaffe ... [et al.] -- Functional studies of regulatory genes in the sea urchin embryo / Vincenzo Cavalieri, Maria Di Bernardo, and Giovanni Spinelli -- Exploring the cytoskeleton during intracytoplasmic sperm injection in humans / Vanesa Y. Rawe and Héctor Chemes -- Somatic cell nuclear transfer in the mouse / Satoshi Kishigami and Teruhiko Wakayama.
  • 2012 Springer
    Niall Barron, editor.
    "MicroRNAs are small, non-coding RNA molecules that interact with target mRNAs to modulate their translation. They are now recognized as widespread and critical regulators of gene expression in the cell. This book is aimed at both industry- and academic-based researchers in the Biopharmaceutical production space who wish to learn more about these fascinating molecules..."--Page [4] of cover.
  • 2003 Wiley
    Michael Hoppert.
    ch. 1. Light Microscopy, p. 1-145 -- ch. 2. Electron Microscopy, p. 147-286 -- ch. 3. Other Microscopical Methods and their Application Potential, p. 287-319.
  • 2013 CRCnetBASE
    Guanghui Ma, Zhiguo Su.
    1. Microspheres for enzyme immobilization / Fei Gao, Yuxia Wang, and Guanghui Ma -- 2. Microspheres for cell culture / Weiqing Zhou, Guanghui Ma, and Zhiguo Su -- 3. Microcapsules for cell transplantation : design, preparation, and application / Guojun Lv, Ying Zhang, Mingqian Tan, Hongguo Xie, and Xiaojun Ma -- 4. Microspheres for the separation and refolding of proteins with an emphasis on particles made of agarose / Jan-Christer Janson -- 5. Microspheres for separation of bioactive small molecules / Fangling Gong, Guifeng Zhang, and Zhiguo Su -- 6. Microspheres for separation of PEG-modified biomolecules / Yongdong Huang, Yanqin Zhai, and Zhiguo Su -- 7. Microspheres for solid-phase organic synthesis / Jing Zhang and Zhiguo Su -- 8. Microspheres for solid-phase modification of proteins / Tao Hu and Zhiguo Su -- 9. Microspheres and microcapsules for protein drug delivery / Lianyan Wang, Tingyuan Yang, and Guanghui Ma -- 10. Micro/nanospheres for gene drug delivery / Jie Wu and Guanghui Ma -- 11. Microspheres for targeting delivery of anticancer drugs / Wei Wei, Zhanguo Yue, Hua Yue, and Guanghui Ma -- 12. Microspheres for targeting delivery to brain / Chen Jiang, Xinguo Jiang, Yang Liu, Kun Shao, and Rongqin Huang -- 13. Nano/microspheres in bioimaging and medical diagnosis / Xiaohui Li and Chunying Chen -- 14. Affinity nanoparticles for detection / Haruma Kawaguchi and Hiroshi Handa.
  • 2010
    Kunal Kumar Ghosh.
    Fluorescence microscopy has emerged as a workhorse of modern biology and medicine. Fluorescence microscopes are indispensable as tools for basic research in the biological sciences, enable platforms for drug discovery in the biotechnology and pharmaceutical industries, and are increasingly aiding in several clinical diagnostic applications. However, state-of-the-art fluorescence microscopes remain bulky and expensive benchtop instruments with an architecture that impedes usage in certain applications and a cost that precludes adoption in large numbers. For example existing benchtop fluorescence microscopes are not amenable for in vivo imaging in animals, with the mouse being a common animal subject, especially during awake, active behavior. For the field of neuroscience in particular, such an experimental capability permits correlating causal cellular processes with animal behavior -- a longstanding goal. Inspired by this need, we have designed a miniature fluorescence microscope that can be borne by a mouse during active behavior. We have fabricated several such microscopes, each less than 2 g in mass, perhaps heralding a transformation in fluorescence microscopy from today's bulky and expensive benchtop paradigm towards miniature and mass-producible devices. Our fabricated microscopes achieve 2.5 μm spatial resolution imaging fields-of-view up to 800 μm x 600 μm at 36 Hz, suitable for cellular-level imaging at high temporal resolution. To facilitate design of our microscopes, we have adopted a modeling-based microscope design methodology, akin to that used in the design of integrated circuits, and have developed a set of tools to model the microscope as an integrated device from the specimen to final digital image. We have experimentally validated fabricated microscopes for in vivo brain imaging in freely behaving mice, specifically using them for: 1) Imaging cerebellar vasculature and hemodynamics during activity; and 2) Imaging cerebellar Purkinje cell Calcium dynamics, analyzing spiking activity of populations of neurons with single neuron specificity during different motor behaviors. We also show how several of these microscopes imaging in parallel can enable new high-throughput imaging solutions with the potential to achieve broad impact, specifically demonstrating high-throughput image-based assays for: 1) Mutant phenotype screening in genetic model species such as the zebrafish; and 2) Multiple well plate cell analyses. Finally, we use a Bayesian iterative image restoration algorithm to enhance acquired microscope images, and show how spatial resolution can be further scaled into the sub-micron regime by leveraging advances in digital image sensing technology in conjunction with our post-acquisition image restoration algorithm.
  • 2013 Springer
    Norma Allewell, Linda O. Narhi, Ivan Rayment (eds.).
    This volume of the series Biophysics for the Life Sciences focuses on the conceptual framework and major research tools of contemporary molecular biophysics. It is designed to enable non-specialists -both students and professionals in other fields - to understand how these approaches can be used across the biosciences and in medicine, agriculture, biotechnology, pharmaceutical development and other fields. The scope of this volume is appropriate for advanced undergraduate and graduate courses in biophysics and biophysical chemistry. The book begins with an overview of the development of molecular biophysics and a brief survey of structural, physical, and chemical principles. Subsequent chapters written by experts present, with examples, the major experimental methods: optical spectroscopy, X-ray and neutron diffraction and scattering, nuclear magnetic resonance, electron paramagnetic resonance, mass spectrometry, and single molecule methods. The relationship between the biophysical properties of biological macromolecules and their roles as molecular machines is emphasized throughout and illustrated with three examples DNA helicases, rotary motor ATPases, and myosin.The concluding chapter discusses future prospects in X-ray and neutron scattering, mass spectrometry, and pharmaceutical development.
  • 2001 ScienceDirect
    edited by Noriyuki Morohoshi, Atsushi Komamine.
  • 2010 ScienceDirect
    [edited by] Wayne W. Grody ... [et al.].
    Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. This handbook provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.
  • 2010 ScienceDirect
    edited by George P. Patrinos, Wilhelm J. Ansorge.
    Chapter 1. Molecular Diagnostics: Past, Present, and Future / George P. Patrinos, Wilhelm J. Ansorge -- Chapter 2 . Allele-Specific Mutation Detection / Aglaia Athanassiadou, Eleana F. Stavrou, Adamandia Papachatzopoulou, George P. Patrinos -- Chapter 3. Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation / Chinh T. Bui, Emmanuelle Nicolas, Georgina Sallmann, Maria Chiotis, Andreana Lambrinakos, Kylee Rees, Ian Trounce, Richard G.H. Cotton, Lauryn Blakesley, Andrew K. Godwin, Anthony T. Yeung -- Chapter 4. Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis / Panayiotis G. Menounos, George P. Patrinos -- Chapter 5. Capillary Electrophoresis / Anja Bosserhoff, Claus Hellerbrand -- Chapter 6. Temperature and Denaturing Gradient Gel Electrophoresis / Hartmut Peters, Peter N. Robinson -- Chapter 7. Real-Time Polymerase Chain Reaction / Lut Overbergh, Anna-Paula Giulietti, Dirk Valckx, Chantal Mathieu -- Chapter 8 - Pyrosequencing / Sharon Marsh -- Chapter 9. Application of Padlock and Selector Probes in Molecular Medicine / Mats Nilsson, Chatarina Larsson, Johan Stenberg, Jenny Göransson, Ida Grundberg, Magnus Isaksson, Tim Conze, Sara Henriksson -- Chapter 10. Molecular Cytogenetics in Molecular Diagnostics / Holger Tönnies -- Chapter 11. Analysis of Human Splicing Defects Using Hybrid Minigenes / Franco Pagani, Francisco E. Baralle -- Chapter 12. Detection of Genomic Duplications and Deletions / Graham R. Taylor, Carol A. Delaney -- Chapter 13. Multiplex Ligation-Dependent Probe Amplification (MLPA) and Methylation-Specific (MS)-MLPA: Multiplex Detection of DNA/mRNA Copy Number and Methylation Changes / Eline M. Sepers, Jan P. Schouten -- Chapter 14. Molecular Techniques for DNA Methylation Studies / Jörg Tost, Ivo G. Gut -- Chapter 15. High-Resolution Melting Curve Analysis for Molecular Diagnostics / Jared S. Farrar, Gudrun H. Reed, Carl T. Wittwer -- Chapter 16. DNA Microarrays and Genetic Testing / Lars Dyrskjøt, Karina Dalsgaard-Sørensen, Marie Stampe-Ostenfeld, Karin Birkenkamp-Demtroder, Kasper Thorsen, Claus L. Andersen, Mogens Kruhøffer, Jens L. Jensen, Torben F. Ørntoft -- Chapter 17. Arrayed Primer Extension Microarrays for Molecular Diagnostics / Neeme Tonisson, Eneli Oitmaa, Kaarel Krjutskov, Janne Pullat, Ilona Lind, Merike Leego, Ants Kurg, Andres Metspalu -- Chapter 18. Application of Proteomics to Disease Diagnostics / Samir Hanash, Ji Qiu, Vitor Faca -- Chapter 19. RNA-Based Variant Detection: The Protein Truncation Test / Johan T. den Dunnen -- Chapter 20. Protein Diagnostics by Proximity Ligation: Combining Multiple Recognition and DNA Amplification for Improved Protein Analyses / Karl-Johan Leuchowius, Ola Söderberg, Masood Kamali-Moghaddam, Malin Jarvius, Irene Weibrecht, Katerina Pardali, Ulf Landegren -- Chapter 21. Mass Spectrometry and its Applications to Functional Proteomics / Thomas Köcher, Giulio Superti-Furga -- Chapter 22. Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Clinical Care / Minoli Perera, Federico Innocenti -- Chapter 23. Nutrigenomics: Integrating Genomic Approaches into Nutrition Research / Lynette R. Ferguson, Martin Philpott, Matthew P.G. Barnett -- Chapter 24. Novel Next-Generation DNA Sequencing Techniques for Ultra High-Throughput Applications in Bio-Medicine / Wilhelm J. Ansorge -- Chapter 25. Locus-Specific and National/Ethnic Mutation Databases: Emerging Tools for Molecular Diagnostics / George P. Patrinos -- Chapter 26. Molecular Diagnostic Applications in Forensic Science / Bruce Budowle, John V. Planz, Rowan Campbell, Arthur J. Eisenberg -- Chapter 27. Mass Disaster Victim Identification Assisted by DNA Typing / Daniel Corach -- Chapter 28. Detection of Highly Pathogenic Viral Agents: Implications for Therapeutics, Vaccines and Biodefense / Kylene Kehn-Hall, Sina Bavari -- Chapter 29. Identification of Genetically Modified Organisms / Farid E. Ahmed -- Chapter 30. Molecular Diagnostics and Comparative Genomics in Clinical Microbiology / Alex van Belkum -- Chapter 31. Genetic Monitoring of Laboratory Rodents / Jean-Louis Guénet, Fernando J. Benavides -- Chapter 32. Safety Analysis in Retroviral Gene Therapy: Identifying Virus Integration Sites in Gene-Modified Cells / Stephanie Laufs, Luisa Schubert, Patrick Maier, W. Jens Zeller, Stefan Fruehauf -- Chapter 33. Preimplantation Genetic Diagnosis / Martine de Rycke, Karen Sermon -- Chapter 34. Automated DNA Hybridization and Detection / Bert Gold -- Chapter 35. The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays / Piotr Grodzinski, Michael Ward, Robin Liu, Kathryn Scott, Saul Surrey, Paolo Fortina -- Chapter 36. Human Gene Patents and Genetic Testing / Timothy Caulfield, Yann Joly -- Chapter 37. Genetic Counseling and Ethics in Molecular Diagnostics / Mary Petrou -- Chapter 38. Genetic Testing and Psychology / Andrea Farkas Patenaude -- Chapter 39. General Considerations Concerning Safety in Biomedical Research Laboratories / William E. Grizzle, Walter C. Bell, Jerry Fredenburgh -- Chapter 40. Quality Management in the Laboratory / David Burnett.
  • 2010 Springer
    Mousumi Debnath, Godavarthi B.K.S. Prasad, Prakash S. Bisen.
  • NCBI Bookshelf
    This searchable database is a collection of in vivo molecular imaging agents developed for positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), ultrasound (US), computed tomography (CT), and optical imaging. MICAD, a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, is being developed by NCBI, the National Center for Biotechnology Information".
  • 2014 Springer Protocols
    edited by Shree Ram Singh, Vincenzo Coppola.
  • Wiley
    edited by Christof M. Niemeyer and Chad A. Mirkin.
    [v. 1]. Concepts, applications, and perspectives -- 1 . Biocompatible inorganic devices / Thomas Sawitowski -- 2. Microfluidics meets nano : lab-on-a-chip devices and their potential for nanobiotechnology / Holger Bartos, Friedrich Götz, and Ralf-Peter Peters -- 3. Microcontact printing of proteins / Emmanuel Delamarche -- 4. Cell-nanostructure interactions / Joachim P. Spatz -- 5. Defined networks of neuronal cells in vitro / Andreas Offenhäusser and Angela K. Vogt -- 6. S-Layers / Uwe B. Sleytr ... [et al.] -- 7. Engineered nanopores / Hagan Bayley ... [et al.] -- 8. Genetic approaches to programmed assembly / Stanley Brown -- 9. Microbial nanoparticle production / Murali Sastry ... [et al.] -- 10. Magnetosomes : nanoscale magnetic iron minerals in bacteria / Richard B. Frankel and Dennis A. Bazylinski -- 11. Bacteriorhodopsin and its potential in technical applications / Norbert Hampp and Dieter Oesterhelt -- 12. Polymer Nanocontainers / Alexandra Graff ... [et al.] -- 13. Biomolecular motors operating in engineered environments / Stefan Diez, Jonne H. Helenius, and Jonathon Howard -- 14. Nanoparticle-biomaterial hybrid systems for bioelectronic devices and circuitry / Eugenii Katz and Itamar Willner -- 15. DNA-protein nanostructures / Christof M. Neimeyer -- 16. DNA-templated electronics / Erez Braun and Uri Sivan -- 17. Biomimetic fabrication of DNA-based metallic nanowires and networks / Michael Mertig and Wolfgang Pompe -- 18. Mineralization in nanostructured biocompartments : biomimetic ferritins for high-density data storage / Eric L. Mayes and Stephen Mann -- 19. DNA-gold nanoparticle conjugates / C. Shad Thaxton and Chad A. Mirkin -- 20. DNA nanostructures for mechanics and computing : nonlinear thinking with life's central molecule / Nadrian C. Seeman -- 21. Nanoparticles as non-viral transfection agents / M.N.V. Ravi Kumar, Udo Bakowsky, and Claus-Michael Lehr -- 22. Luminescent quantum dots for biological labeling / Xiaohu Gao and Shuming Nie -- 23. Nanoparticle molecular labels / James F. Hainfeld, Richard D. Powell, and Gerhard W. Hacker -- 24. Surface biology : analysis of biomolecular structure by atomic force microscopy and molecular pulling / Emin Oroudjev, Signe Danielsen and Helen G. Hansma -- 25. Force spectroscopy / Markus Seitz -- 26. Biofunctionalized nanoparticles for surface-enhanced raman scattering and surface plasmon resonance / Mahnaz El-Kouedi and Christine D. Keating -- 27. Bioconjugated silica nanoparticles for bioanalytical applications / Timothy J. Drake, Xiaojun Julia Zhao, and Weihong Tan. -- v. 2. More concepts and applications -- Part I. Self-Assembly and Nanoparticles: Novel Principles -- ch. 1. Self-Assembled Artificial Transmembrane Ion Channels / Mary S. Gin, Emily G. Schmidt and Pinaki Talukdar, p. 1-15 -- ch. 2. Self-Assembling Nanostructures from Coiled-Coil Peptides / Maxim G. Ryadnov and Derek N. Woolfson, p. 17-38 -- ch. 3. Synthesis and Assembly of Nanoparticles and Nanostructures Using Bio-Derived Templates / Erik Dujardin and Stephen Mann, p. 39-63 -- ch. 4. Proteins and Nanoparticles: Covalent and Noncovalent Conjugates / Rochelle R. Arvizo, Mrinmoy De and Vincent M. Rotello, p. 65-78 -- ch. 5. Self-Assembling DNA Nanostructures for Patterned Molecular Assembly / Thomas H. LaBean, Kurt V. Gothelf and John H. Reif, p. 79-97 -- ch. 6. Biocatalytic Growth of Nanoparticles for Sensors and Circuitry / Ronan Baron, Bilha Willner and Itamar Willner, p. 99-121 -- Part II. Nanostructures for Analytics -- ch. 7. Nanoparticles for Electrochemical Bioassays / Joseph Wang, p. 123-140 -- ch. 8. Luminescent Semiconductor Quantum Dots in Biology / Thomas Pons, Aaron R. Clapp, Igor L. Medintz and Hedi Mattoussi, p. 141-157 -- ch. 9. Nanoscale Localized Surface Plasmon Resonance Biosensors / Katherine A. Willets, W. Paige Hall, Leif J. Sherry, Xiaoyu Zhang, Jing Zhao and Richard P. Van Duyne, p. 159-173 -- ch. 10. Cantilever Array Sensors for Bioanalysis and Diagnostics / Hans Peter Lang, Martin Hegner and Christoph Gerber, p. 175-195 -- ch. 11. Shear-Force-Controlled Scanning Ion Conductance Microscopy / Tilman E. Schäffer, Boris Anczykowski, Matthias Böcker and Harald Fuchs, p. 197-212 -- ch. 12. Label-Free Nanowire and Nanotube Biomolecular Sensors for In-Vitro Diagnosis of Cancer and other Diseases / James R. Heath, p. 213-232 -- ch. 13. Bionanoarrays / Rafael A. Vega, Khalid Salaita, Joseph J. Kakkassery and Chad A. Mirkin, p. 233-259 -- Part III. Nanostructures for Medicinal Applications --. ch. 14. Biological Barriers to Nanocarrier-Mediated Delivery of Therapeutic and Imaging Agents, p. 261-284 / Rudy Juliano -- ch. 15. Organic Nanoparticles: Adapting Emerging Techniques from the Electronics Industry for the Generation of Shape-Specific, Functionalized Carriers for Applications in Nanomedicine / Larken E. Euliss, Julie A. DuPont and Joseph M. DeSimone, p. 285-303 -- ch. 16. Poly(amidoamine Dendrimer-Based Multifunctional Nanoparticles / Thommey P. Thomas, Rameshwer Shukla, Istvan J. Majoros, Andrzej Myc and James R. Baker, p. 305-319 -- ch. 17. Nanoparticle Contrast Agents for Molecular Magnetic Resonance Imaging / Young-Wook Jun, Jae-Hyun Lee and Jinwoo Cheon, p. 321-346 -- ch. 18. Micro- and Nanoscale Control of Cellular Environment for Tissue Engineering / Ali Khademhosseini, Yibo Ling, Jeffrey M. Karp and Robert Langer, p. 347-364 -- ch. 19. Diagnostic and Therapeutic Targeted Perfluorocarbon Nanoparticles / Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza and Samuel A. Wickline, p. 365-380 -- Part IV. Nanomotors -- ch. 20. Biological Nanomotors / Manfred Schliwa, p. 381-399 -- ch. 21. Biologically Inspired Hybrid Nanodevices / David Wendell, Eric Dy, Jordan Patti and Carlo D. Montemagno, p. 401-418.
  • 2012 Springer
    Eran Zahavy ... [et al.], editors.
    Biomolecule/nanomaterial hybrid systems for nanobiotechnology -- Superresolution optical fluctuation imaging (SOFI) -- Application of nanoparticles for the detection and sorting of pathogenic bacteria by flow-cytometry -- Advancing nanostructured porous si-based optical transducers for label free bacteria detection -- Gold fibers as a platform for biosensing -- Surface-enhanced raman spectroscopy of organic molecules adsorbed on metallic nanoparticles -- Quantum dots and fluorescent protein FRET-based biosensors -- Semiconductor quantum dots as FRET acceptors for multiplexed diagnostics and molecular ruler application -- Assembly and microscopic characterization of DNA origami structures -- DNA nanotechnology -- Role of carbohydrate receptors in the macrophage uptake of dextran-coated iron oxide nanoparticles -- Toxicity of gold nanoparticles on somatic and reproductive cells -- Ultrasound activated nano-encapsulated targeted drug delivery and tumour cell poration -- Ultrasound mediated localized drug delivery -- Sonochemical proteinaceous microspheres for wound healing -- Alendronate liposomes for antitumor therapy: activation of [gamma] [delta] T cells and inhibition of tumor growth.
    Also available: Print – 2012
  • 2013 Springer Protocols
    edited by Sandra J. Rosenthal and David W. Wright.
    High-aspect-ratio gold nanorods : their synthesis and application to image cell-induced strain fields in collagen films / Davin J. Chernak ... [et al.] -- Imaging intracellular quantum dots : fluorescence microscopy and transmission electron microscopy / Craig J. Szymanski ... [et al.] -- Imaging of cell populations in atherosclerosis using quantum dot nanocrystals / Joshua R. Trantum and Ashwath Jayagopal -- Imaging of endothelial progenitor cell subpopulations in angiogenesis using quantum dot nanocrystals / Joshua M. Barnett, John S. Penn, and Ashwath Jayagopal -- Imaging single synaptic vesicles in mammalian central synapses with quantum dots / Qi Zhang -- Quantum dot-based single-molecule microscopy for the study of protein dynamics / Jerry C. Chang and Sandra J. Rosenthal -- Three-dimensional molecular imaging with photothermal optical coherence tomography / Melissa C. Skala ... [et al.] -- Detecting respiratory syncytial virus using nanoparticle-amplified immuno-PCR / Jonas W. Perez ... [et al.] -- Gold nanoparticle-oligonucleotide conjugates for the profiling of malignant melanoma phenotypes / John W. Stone ... [et al.] -- Methods for isolating RNA sequences capable of binding to or mediating the formation of inorganic materials / Carly Jo Carter, Alina Owczarek, and Daniel L. Feldheim -- Single-walled carbon nanotube-mediated small interfering RNA delivery for gastrin-releasing peptide receptor silencing in human neuroblastoma / Jingbo Qiao ... [et al.] -- Amino acid mediated linear assembly of au nanomaterials / Manish Sethi and Marc R. Knecht -- Enzyme-gold nanoparticle bioconjugates : quantification of particle stoichiometry and enzyme specific activity / Jacqueline D. Keighron and Christine D. Keating -- In vivo testing for gold nanoparticle toxicity / Carrie A. Simpson, Brian J. Huffman, and David E. Cliffel -- Methods for studying toxicity of silica-based nanomaterials to Living Cells / Yang Zhao ... [et al.].
  • 2006 Springer
    edited by M. Reza Mozafari.
    Also available: Print – 2006
  • 2013 Springer Protocols
    edited by Paolo Bergese, Kimberly Hamad-Schifferli.
    Preparation of 2 nm gold nanoparticles for in vitro and in vivo applications / Daniel F. Moyano, Bradley Duncan, and Vincent M. Rotello -- DNA conjugation to nanoparticles / Sunho Park -- Conjugation of nanoparticles to proteins / Marie-Eve Aubin-Tam -- Water-solubilization and functionalization of semiconductor quantum dots / Christina M. Tyrakowski, Adela Isovic, and Preston T. Snee -- Synthesizing and modifying peptides for chemoselective ligation and assembly into quantum dot-peptide bioconjugates / W. Russ Algar ... [et al.] -- Reliable methods for silica coating of au nanoparticles / Isabel Pastoriza-Santos and Luis M. Liz-Marzán -- Surface modifications by polymers for biomolecule conjugation / Laura Sola ... [et al.] -- Functionalization protocols of silicon micro/nano- mechanical biosensors / Francesca Frascella and Carlo Ricciardi -- Stability and aggregation assays of nanoparticles in biological media / James Chen Yong Kah -- Electrochemical measurements of DNA melting on surfaces / Irina Belozerova, Dongbiao Ge, and Rastislav Levicky -- Formation and characterization of the nanoparticle-protein corona / Marco P. Monopoli ... [et al.] -- Electrophoretic implementation of the solution-depletion method for measuring protein adsorption, adsorption kinetics, and adsorption competition among multiple proteins in solution / Hyeran Noh ... [et al.] -- Hyperspectral microscopy for characterization of gold nanoparticles in biological media and cells for toxicity assessment / Christin Grabinski, John Schlager, and Saber Hussain -- Immunocytochemistry, electron tomography, and energy dispersive x-ray spectroscopy (EDXS) on cryosections of human cancer cells doped with stimuli responsive polymeric nanogels loaded with iron oxide nanoparticles / Roberto Marotta ... [et al.] -- Zwitterion siloxane to passivate silica against nonspecific protein adsorption / Zaki G. Estephan and Joseph B. Schlenoff -- Preparation and characterization of DNA block copolymer assemblies loaded with nanoparticles / Xi-Jun Chen, Robert J. Hickey, and So-Jung Park -- Polyaspartic acid coated iron oxide nanoprobes for PET/MRI imaging / Taku Cowger and Jin Xie -- Ligand synthesis and passivation for silver and large gold nanoparticles for single-particle-based sensing and spectroscopy / Daniel Montiel ... [et al.] -- Noncovalent intracellular drug delivery of hydrophobic drugs on au NPs / Tennyson Doane and Clemens Burda -- Modification of carbon nanotubes for gene delivery vectors / Victor Ramos-Perez ... [et al.] -- Lipid-based nanoparticles as nonviral gene delivery vectors / Daniele Pezzoli ... [et al.] -- Stabilizing gold nanoparticle bioconjugates in physiological conditions by PEGylation / Joan Comenge and Víctor F. Puntes.
  • 2007 Springer
    edited by M. Resa Mozafari.
    Micro and nano systems in biomedicine and drug delivery / Nesrin Hasirci -- Newlipid- and glycolipid-based nanosystems for targeted gene delivery: cholenims, glycoclips, and chitosan / R.I. Zhdanov ... [et. al] -- Artificial implants - new developments and associated problems / Abdelwahab Omri -- Niosomes as nanocarrier systems / Nefise Ozlen Sahin -- Starch - a potential biomaterial for biomedical application / Lovedeep Kaur, Jaspreet Singh, Qiang Liu -- Alternative applications for drug delivery: nasal and pulmonary routes / A. Yekta Ozer -- An overview of lipsome-derived nanocarrier technologies / M. Reza Mozafari, Kianoush Khosravi-Darani -- Uptake studies of free and liposomal sclareol by MCF-7 and H-460 human cancer cell lines / Agnes Paradissi ... [et. al] -- Release advantages of a liposomal dendrimer- doxorubicin complex, over conventional liposomal formulation of doxorubicin / Aristarchos Papagiannoros, Costas Demetzos -- Applications of light and electron microscopic techniques in liposome research / A. Yekta Ozer.
  • 2012 Springer Protocols
    edited by Maria E. Gracheva.
    Detecting and characterizing individual molecules with single nanopores -- Protein sensing with engineered protein nanopores -- Measurements of DNA immobilized in the alpha-hemolysin nanopore -- DNA unzipping and protein unfolding using nanopores -- DNA characterization with ion beam-sculpted silicon nitride nanopores -- DNA sequencing by nanopore-induced photon emission -- Optical tweezers for mechanical control over DNA in a nanopore -- Analyzing single DNA molecules by nanopore translocation -- DNA characterization by transverse electrical current in a nanochannel -- Optimization of the molecular dynamics method for simulations of DNA and ion transport through biological nanopores -- Polymer translocation through an electrically tunable nanopore in a multilayered semiconductor membrane -- Graphene nanopore devices for DNA sensing -- Measuring single-wall carbon nanotubes with solid-state nanopores -- Passive and electrically actuated solid-state nanopores for sensing and manipulating DNA.
  • 2011 Springer Protocols
    edited by Ping Wang.
    Nanoscale-engineered cytochrome P450 system with a branch structure / Hidehiko Hirakawa and Teruyuki Nagamune -- Chemically induced self-assembly of enzyme nanorings / Brian R. White, Qing Li, and Carston R. Wagner -- Self-assemblies of polymer-enzyme conjugates at oil-water interfaces for interfacial biocatalysis / Guangyu Zhu and Ping Wang -- Molecular assembly-assisted biocatalytic reactions in ionic liquids / Muhammad Moniruzzaman and Masahiro Goto -- Organic-soluble enzyme nano-complexes formed by ion-pairing with surfactants / Songtao Wu, Andreas Buthe, and Ping Wang -- Enzyme-immobilized CNT network probe for in vivo neurotransmitter detection / Gi-Ja Lee [and others] -- Kinesin I ATPase manipulates biohybrids formed from tubulin and carbon nanotubes / Cerasela Zoica Dinu [and others] -- Reversible his-tagged enzyme immobilization on functionalized carbon nanotubes as nanoscale biocatalyst / Liang Wang and Rongrong Jiang -- TiO2 nanoparticle system for sacrificial solar H2 production prepared by rational combination of a hydrogenase with a ruthenium photosensitizer / Erwin Reisner and Fraser A. Armstrong -- Preparation and characterization of single-enzyme nanogels / Jun Ge [and others] -- Fabrication and characterization of bioactive thiol-silicate nanoparticles / Frances Neville and Paul Millneri -- Immobilization of enzymes on fumed silica nanoparticles for applications in nonaqueous media / Juan C. Cruz [and others] -- Microencapsulation of bioactive nanoparticles / Fei Gao, Ping Wang, and Guanghui Ma -- Engineering the logical properties of a genetic and gate / Daniel J. Sayut, Yan Niu, and Lianhong Sun -- Strain engineering strategies for improving whole-cell biocatalysis : engineering Escherichia coli to overproduce xylitol as an example / Jonathan W. Chin and Patrick C. Cirino -- Enzyme-carrying electrospun nanofibers / Hongfei Jia -- Uniform lab-scale biocatalytic nanoporous latex coatings for reactive microorganisms / Jimmy L. Gosse and Michael C. Flickinger -- Entrapment of enzymes in nanoporous sol-gels / Andreas Buthe.
  • 2005 CRCnetBASE
    edited by Ralph S. Greco, Fritz B. Prinz, R. Lane Smith.
  • 2013 Springer Protocols
    edited by Manfred Ogris, David Oupicky.
    Toxicological aspects for nanomaterial in humans -- Lactate dehydrogenase assay for assessment of polycation cytotoxicity -- Combined fluorimetric caspase 3/7 assay and bradford protein determination for assessment of polycation-mediated cytotoxicity -- Anti-PEG igm production via a PEGylated nano-carrier system for nucleic acid delivery -- Near-infrared optical imaging of nucleic acid nanocarriers in vivo -- Lipids for nucleic acid delivery: Synthesis and particle formation -- Histidine-rich cationic amphipathic peptides for plasmid DNA and siRNA delivery -- Synthesis of polyethylenimine-based nanocarriers for systemic tumor targeting of nucleic acids -- Synthesis of bioreducible polycations with controlled topologies -- Lyophilization of synthetic gene carriers -- Surface- and hydrogel-mediated delivery of nucleic acid nanoparticles -- Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids -- In situ AFM analysis investigating disassembly of DNA nanoparticles and nano-films -- Enhancing nucleic acid delivery with ultrasound and microbubbles -- Magnetic and acoustically active microbubbles loaded with nucleic acids for gene delivery -- Synthesis of lipidic magnetic nanoparticles for nucleic acid delivery -- Lipopeptide delivery of siRNA to the central nervous system -- Flow cytometry-based cell type-specific assessment of target regulation by pulmonary siRNA delivery -- Liver-targeted gene delivery through retrograde intrabiliary infusion.
  • 2012 Springer Protocols
    edited by Melba Navarro, Josep A. Planell.
    Is nanotechnology the key to unravel and engineer biological processes? -- Synthesis of genetically engineered protein polymers (recombinamers) as an example of advanced self-assembled smart materials -- Design of biomolecules for nanoengineered biomaterials for regenerative medicine -- Stimuli responsive polymers for nanoengineering of biointerfaces -- Micro/nanopatterning of proteins using a nanoimprint-based contact printing technique -- Functionalization of surfaces with synthetic oligonucleotides -- Fabrication of PEG hydrogel microwell arrays for high-throughput single stem cell culture and analysis -- Preparation of polyelectrolyte nanocomplexes containing recombinant human hepatocyte growth factor as potential oral carriers for liver regeneration -- Electrospinning technology in tissue regeneration -- Protein adsorption characterization -- Measuring wettability of biosurfaces at the microscale -- AFM to study bio/nonbio interactions -- Evaluation of cytocompatibility and cell response to boron nitride nanotubes -- Nanobiosensors for in vitro and in vivo analysis of biomolecules -- Novel strategies to engineering biological tissue in vitro -- Enabling biomedical research with designer quantum dots -- The role of nanophotonics in regenerative medicine -- Molecular dynamics methods for modeling complex interactions in biomaterials -- Regenerative nanomedicine: ethical, legal, and social issues.
  • 2001 CRCnetBASE
    edited by Ramesh Raghavachari.
  • 2011
    Dongjun Shin.
    The increasing demand for physical interaction between humans and robots has led to an interest in robots whose behavior is guaranteed to be safe when they are in close proximity with humans. However, attaining sufficiently high levels of performance while ensuring safety creates formidable challenges in mechanical design, actuation, sensing, and control. To promote safety without compromising performance, a new actuation concept, referred to as hybrid actuation, has been developed. Since low impedance output at high frequencies is essential for robot safety, while optimal passive stiffness is needed for robot performance, the new actuation approach employs a pneumatic artificial muscle as a macro actuator to provide low-frequency torques. Artificial pneumatic muscles provide high force-to-weight ratio and inherent compliance, both of which allow for low impedance actuation. To compensate for the slow and non-linear dynamics of pneumatic actuation, a small electromagnetic actuator collocated at the robot's joint is employed as a mini actuator, which provides high mechanical bandwidth for high performance without increasing the inertia and size of the manipulator. To achieve the appropriate balance between safety and performance, design methodologies were developed that optimally determine key design parameters such as the required mini motor torque capacity, the joint stiffness introduced by an antagonistic pair of muscles, and the pulley radius. Using a testbed, referred to as the Stanford Safety Robot (S2rho), the hybrid actuation was evaluated for position tracking performance, force tracking performance, and impact behavior. The experimental results demonstrate that by significantly improving control performance with the hybrid actuation over performance with pneumatic muscles alone, while reducing the effective inertia significantly, the competing design objectives of safety and performance can be successfully integrated into a single robotic manipulator. As an extension of the hybrid actuation concept, the new design of dual four-degree-of-freedom robotic arms with torso is presented and detailed descriptions of the design are included.
  • 2008 Karger
    volume editors, Philippe Poindron, Pascale Piguet.
    Theoretical considerations on animal models / Poindron, P., Callizot, N., Piguet, P. -- Mouse models with motor neuron defects as a tool for deciphering amyotrophic lateral sclerosis. Applications, limits, and future challenges / Echaniz-Laguna, A. ... [et al.] -- A chronic relapsing animal model for multiple sclerosis. Myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis in dark agouti rats / Kinter, J., Zeis, T., Schaeren-Wiemers, N. -- Occlusion of the middle cerebral artery in rats. Refinement of an animal model for human stroke / Cam, E. ... [et al.] -- Pyridoxine-induced peripheral neuropathy. Animal models and uses / Callizot, N., Poindron, P. -- A dopamine-sensitive inherited motor syndrome linked to the frissonnant mutation / Callizot, N., Guenet, J.-L., Poindron, P.
  • 2012 Springer
    Avi Ma'ayan, Ben D. MacArthur, editors.
    Gene Expression Profiling and Regulatory Networks in Single Cells / Fumio Arai, Kentaro Hosokawa, Yoshiko Matsumoto, Hirofumi Toyama and Toshio Suda -- Cell Fate Regulatory Networks / Sonya J. Ridden and Ben D. MacArthur -- Noise in Regulatory Networks / Srinandan Dasmahapatra -- Generalised Modelling in Systems Biology / Thilo Gross -- Relative Quantification Mass Spectrometry Using iTRAQ Isobaric Tags / Richard D. Unwin, Emma Carrick and Anthony D. Whetton -- Deciphering Protein Complexes and Protein Interaction Networks for Stem Cell Pluripotency / Jianlong Wang -- Omics Era in Stem Cell Research: Data Integration of Multi-regulatory Layers / Ana Sevilla, Benjamin Trinite and Ihor R. Lemischka -- High Throughput Affinity Purification and Mass Spectrometry to Determine Protein Complex Interactions / Anna Malovannaya, Rainer B. Lanz, Bert W. O'Malley and Jun Qin -- Network Pharmacology to Aid the Drug Discovery Process / Ruth Dannenfelser, Huilei Xu, Catherine Raimond and Avi Ma'ayan -- What Can Networks Do for You? / Bernhard M. Schuldt, Franz-Josef Müller and Andreas A. Schuppert.
  • 2007 ScienceDirect
    editor, Keith R. Mitchelson.
    Overview: developments in DNA sequencing / Keith R. Mitchelson ... [et al.] -- Chip capillary electrophoresis and total genetic analysis systems / Quiang Xiong and Jing Cheng -- Comparative sequence analysis by MALDI-TOF mass spectrometry: utilizing the known to discover the new / Mathias Ehrich, Franz Hillenkamp, and Dirk van den Boom -- Advances in dye-nucleotide conjugate chemistry for DNA sequencing / Shiv Kumar and Carl W. Fuller -- The 454 life sciences picoliter sequencing system / Marcel Margulies ... [et al.] -- An integrated system for DNA sequencing by synthesis / John R. Edwards, Dae Hyun Kim, and Jingyue Ju -- Single-molecule fluorescence microscopy and its applications to single-molecule sequencing by cyclic synthesis / Benedict Hebert and Ido Braslavsky -- Rapid DNA sequencing by direct nanoscale reading of nucleotide bases on individual DNA chains / James Weifu Lee and Amit Meller -- A single molecule system for whole genome analysis / Shiguo Zhou, Jill Herschleb, and David C. Schwartz -- Sequencing aided by mutagenesis facilitates the de novo sequencing of megabase DNA fragments by short read lengths / Jonathan M. Keith ... [et al.] -- Genome sequencing and assembly / Annette McGrath -- Valid recovery of nucleic acid sequence information from high contamination risk samples: ancient DNA and environmental DNA / George A. Kowalchuk ... [et al.].
  • 2005 Karger
    volume editors, Philippe Poindron, Pascale Piguet, Eckart Förster.
    Hippocampal slice cultures / Förster, E., Bartos, M., Zhao, S. -- Protocol for the primary culture of cortical neurons / Gonthier, B. ... [et al.] -- A new technique to control the architecture of neuronal networks in vitro / Wyart, C. ... [et al.] -- Organotypic cultures of the rat retina / Hofmann, H.-D. ... [et al.] -- Cerebellar slice cultures / Kapfhammer, J.P. -- Culture of dissociated hippocampal neurons / Rigato, F. -- Improved methods for culturing rat and mouse motor neurons. Their applications / Guettier-Sigrist, S. ... [et al.] -- Characterization of long-term cultured cell lines of murine microglia called MAMI. The case for MAMI-96 cell line / Laporte, V. ... [et al.].
  • 2012 Springer Protocols
    edited by Jian-Bing Fan.
    Controlling miRNA regulation in disease / Willemijn M. Gommans and Eugene Berezikov -- Introduction to miRNA profiling technologies and cross-platform comparison / Sarah Aldridge and James Hadfield -- Stem-loop RT-qPCR for microRNA expression profiling / James Hurley [and others] -- Poly(T) adaptor RT-PCR / Rui-Shi [and others] -- MicroRNA in situ hybridization / Boye Schnack Nielsen -- Agilent microRNA microarray profiling system / Petula N. D'Andrade and Stephanie Fulmer-Smentek -- MiRNA expression profiling using Illumina Universal BeadChips / Jing Chen, Craig S. April, and Jian-Bing Fan -- MicroRNA expression analysis using the Affymetrix platform / Suzanne Dee and robert C. Getts -- Individualized miRNA assay panels using optically encoded beads / Keld Sorensen -- Microfluidic primer extension assay / Markus Beier and Valesca Boisguérin -- MicroRNA profiling using [mu]Paraflo microfluidic array technology / Xiaochuan Zhou [and others] -- MicroRNA expression analysis using the Illumina microRNA-Seq platform / Shujun Luo -- Next-generation sequencing of miRNAs with Roche 454 GS-FLX technology : steps for a successful application / Ana Raquel Soares, Patrícia M. Pereira, and Manuel A.S. Santos -- Methods for small RNA preparation for digital gene expression profiling by next-generation sequencing / Sam E.V. Linsen and Edwin Cuppen -- Profiling of short RNAs using Helicos single-molecule sequencing / Philipp Kapranov, Fatih Ozsolak, and Patrice M. Milos -- DeepBASE : annotation and discovery of microRNAs and other noncoding RNAs from deep-sequencing data / Jian-Hua Yang and Liang-Hu Qu -- PhenomiR : microRNAs in human diseases and biological processes / Andreas Ruepp, Andreas Kowarsch, and Fabian Theis -- MiRNA expression profiling : from reference genes to global mean normalization / Barbara D'haene [and others] -- MiRNA data analysis : next-gen sequencing / Preethi H. Gunaratne [and others] -- Integrated miRNA expression analysis and target prediction / William Ritchie and John E.J. Rasko -- MiRNAs in human cancer / Xiaomin Zhong, George Coukos, and Lin Zhang -- Blood-based miRNA preparation for noninvasive biomarker development / Svenja Debey-Pascher [and others].
  • 2011 Springer
    Justin Ainscough, Shinya Yamanaka, Takashi Tada, editors.
    Annotation Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mechanisms that drive disease aetiology the research is realistically opening the doors for development of targeted and personalized therapeutic applications that many considered, until recently, to be nothing more that a far fetched dream. This volume provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years. Since the early 1950s a small number of notable experiments have provided significant impetus to the field, primarily the demonstration of reprogramming ability, first by the complex cytoplasmic milieu that constitutes the amphibian egg, then that of the mammalian egg, and finally that of the mammalian embryonic stem cell. Most recently, the demonstration that a limited pool of defined molecules is capable of reprogramming a multitude of cell types has provided massive impetus and facilitated transition towards realistic therapeutic application. We have therefore reproduced some of the key articles that elegantly document these dramatic stages of development of the field in an inclusive appendix to the book, for the benefit of readers keen to investigate the history of how the field of stem cell biology has evolved. Owing to the ever broadening nature of this field, and the incredible rate at which it is evolving, the main content of this volume focuses on areas that have shown significant movement in recent years, are most likely to translate into personalized therapeutic application, and thus provide greatest potential for significant impact on human health in the not too distant future. We recognize that research into many other disease states and cell types are all equally worthy of discussion. We would therefore like to acknowledge those researchers involved whose work we have not been able to include in this volume. Nuclear Reprogramming and Stem Cells will serve as a valuable resource for all researchers in the field of stem cell biology, including those just setting out on their career path as well as those already established in the field.
  • 2006 CRCnetBASE
    edited by Fereidoon Shahidi
    1. Nutraceutical and Specialty Lipids / Fereidoon Shahidi and S.P.J.N. Senanayake -- 2. Medium-Chain Triacylglycerols / Yaakob B. Che Man and Marina Abdul Manaf -- 3. Cereal Grain Oils / Roman Przybylski -- 4. Fruit Seed Oils / Liangli Yu, John W. Parry, and Kequan Zhou -- 5. Minor Specialty Oils / Frank D. Gunstone -- 6. Sphingolipids / Fang Fang, Hang Chen, Chi-Tang Ho, and Robert T. Rosen -- 7. Modification and Purification of Sphingolipids and Gangliosides / Scott Bloomer -- 8. Hydroxy Fatty Acids / Thomas A. McKeon, Charlotta Turner, Xiaohua He, Grace Chen, and Jiann-Tsyh Lin -- 9. Tree Nut Oils and Byproducts: Compositional Characteristics and Nutraceutical Applications / Fereidoon Shahidi and H. Miraliakbari -- 10. Gamma-Linolenic Acid (GLA) / Yao-wen Huang and Chung-yi Huang -- 11. Diacylglycerols (DAGs) and their Mode of Action / Brent D. Flickinger -- 12. Conjugated Linoleic Acids (CLAs): Food, Nutrition, and Health / Bruce A. Watkins and Yong Li -- 13. Occurrence of Conjugated Fatty Acids in Aquatic and Terrestrial Plants and their Physiological Effects / Bhaskar Narayan, Masashi Hosokawa, and Kazuo Miyashita -- 14. Marine Conjugated Polyunsaturated Fatty Acids / Yasushi Endo, Si-Bum Park, and Kenshiro Fujimoto -- 15. Marine Oils: Compositional Characteristics and Health Effects / Fereidoon Shahidi and H. Miraliakbari -- 16. Single-Cell Oils as Sources of Nutraceutical and Specialty Lipids: Processing Technologies and Applications / S.P.J.N. Senanayake and Jaouad Fichtali -- 17. Emulsions for the Delivery of Nutraceutical Lipids / Karlene S.T. Mootoosingh and Dérick Rousseau -- 18. Lipid Emulsions for Total Parenteral Nutrition (TPN) Use and as Carriers for Lipid-Soluble Drugs / Hu Liu and Lili Wang -- 19. Modified Oils / Frank D. Gunstone -- 20. Fat Replacers: Mimetics and Substitutes / Barry G. Swanson -- 21. Application of Functional Lipids in Foods / Charlotte Jacobsen, Maike Timm-Heinrich, and Nina Skall Nielsen -- 22. Application of Multistep Reactions with Lipases to the Oil and Fat Industry / Yuji Shimada, Toshihiro Nagao, and Yomi Watanabe -- 23. Structure-Related Effects on Absorption and Metabolism of Nutraceutical and Specialty Lipids / Armand B. Christophe -- 24. Lipid Oxidation in Specialty Oils / Karen Schaich -- 25. Trans Fatty Acids in Specialty Lipids / G.R. List, R.O. Adlof, and J.W. King -- 26. Tocopherols and Tocotrienols as Byproducts of Edible Oil Processing / Vitamin E: A New Perspective Andreas M. Papas -- 27. Plant Sterols and Steryl Esters in Functional Foods and Nutraceuticals / Nikolaus Weber and Kumar D. Mukherjee -- 28. Phospholipids/Lecithin: A Class of Nutraceutical Lipids / Frank T. Orthoefer and G.R. List -- 29. Centrifugal Partition Chromatography (CPC) as a New Tool for Preparative-Scale Purification of Lipid and Related Compounds / Udaya Wanasundara and Paul Fedec -- 30. Oilseed Medicinals: Applications in Drugs and Functional Foods / Robert D. Reichert.
  • 2012 CRCnetBASE
    edited by Debmalya Barh, Kenneth Blum, Margaret Anne Madigan.
    Section 1. Methodology and application -- section 2. Empirical research -- section 3. Computational and systems biology -- section 4. Therapeutics -- section 5. Future perspective.
  • 2013 Springer
    Debmalya Barh, Dipali Dhawan, Nirmal Kumar Ganguly, editors.
    Omics for Personalized Medicine will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.
  • 2015 Springer Protocols
    edited by Santi M. Spampinato.
    Overview of genetic analysis of human opioid receptors / Santi M. Spampinato -- Computational structural biology of opioid receptors / Davide Provasi -- Analysis of epigenetic mechanisms regulating opioid receptor gene transcription / Cheol Kyu Hwang [and three others] -- Renilla luciferase reporter assay to study 3'UTR-Driven posttranscriptional regulations of OPRM1 / Gabriele Vincelli and Andrea Bedini -- High-throughput gene expression profiling of opioid-induced alterations in discrete brain areas / Michal Korostynski [and three others] -- Real-time imaging of mu opioid receptors by total internal reflection fluorescence microscopy / Cristina Roman-Vendrell and Guillermo Ariel Yudowski -- In vivo techniques to investigate the internalization profile of opioid receptors / Amynah A. Pradhan [and three others] -- Monitoring opioid receptor dimerization in living cells by bioluminescence resonance energy transfer (BRET) / Monica Baiula -- Analysis of potassium and calcium imaging to assay the function of opioid receptors / Viola Spahn, Dinah Nockemann, and Halina Machelska -- Electrophysiological patch clamp assay to monitor the action of opioid receptors / Viola Spahn, Dinah Nockemann, and Halina Machelska -- Skin-nerve preparation to assay the function of opioid receptors in peripheral endings of sensory neurons / Rabih Moshourab, Yvonne Schmidt, and Halina Machelska -- Mechanical nociception measurement in mice and rats with automated Von Frey equipment / Gabriele Campana and Roberto Rimondini -- Detecting zinc release induced by mu-opioid receptor agonists in brain slices / María Rodríguez-Muñoz [and three others] -- Opioid receptors : methods for detection and their modes of actions in the eye / Shahid Husain -- Evaluation of murine macrophage cytokine production after in vivo morphine treatment / Silvia Franchi [and four others] -- Measurement of macrophage toll-like receptor 4 expression after morphine treatment / Mara Castelli [and three others] -- The role of opioid receptors in migration and wound recovery in vitro in cultured human keratinocytes and fibroblasts / Mei Bigliardi-Qi and Paul L. Bigliardi -- Role of opioid receptors in the reinstatement of opioid- seeking behavior : an overview / Liana Fattore [and three others] -- Analysis of opioid-seeking reinstatement in the rat / Liana Fattore [and three others] -- Induction of a high alcohol consumption in rats and mice : role of opioid receptors / Roberto Rimondini and Gabriele Campana -- Evaluation of social and nonsocial behaviors mediated by opioids in mouse pups / Francesca R. D'Amato.
  • 2014 CRCnetBASE
    edited by Stephen P. Morgan, Felicity R.A.J. Rose, Stephen J. Matcher.
    "This book is focused on the optical techniques that can be applied to regenerative medicine, including optical coherence tomography, acousto-optic imaging, Raman spectroscopy, machine vision, polarized light imaging, fibre optic sensors, second harmonic generation, multi-photon microscopy, coherent anti-Stokes Raman scattering, and polarized light imaging. It covers applications both in fundamental research and in the regenerative medicine industry for tissue engineering products. Each chapter gives an overview of a particular technique, its advantages and limitations in terms of structural and functional information provided, and examples of applications in regenerative medicine. The book provides a practical guide to the most appropriate techniques for a given application. It also offers a summary of major recent advances, such as use of machine vision for tracking growth of three-dimensional constructs in bioreactors and polarization sensitive optical coherence tomography for monitoring collagen alignment in cartilage growth"--Provided by publisher.
  • 2013 Springer Protocols
    edited by Joydeep Basu, John W. Ludlow.
    1. Isolation and characterization of human adipose-derived stem cells for use in tissue engineering / Benjamin M. Buehrer and Bentley Cheatham -- 2. Isolation of smooth muscle cells from bladder for generation of engineered urologic organs / Darell W. McCoy -- 3. Isolation of urothelial cells from bladder tissue / Namrata Sangha -- 4. Isolation of pulsatile cell bodies from esophageal tissue / John W. Ludlow, Joydeep Basu, Christopher W. Genheimer, Kelly I. Guthrie, and Namrata Sangha -- 5. Cell isolation through whole-liver perfusion and preparation of hepatocytes for cytochrome P450 analysis / Sonya O. Meheux -- 6. Ex vivo culture and separation of functional renal cells / Andrew T. Bruce, Kelly I. Guthrie, and Rusty Kelley -- 7. Isolation and myogenic differentiation of mesenchymal stem cells for urologic tissue engineering / Rongpei Wu, Guihua Liu, Shantaram Bharadwaj and Yuanyuan Zhang -- 8. Xeno-free adaptation and culture of human pluripotent stem cells / Tori Sampsell-Barron -- 9. Reverse engineering life : physical and chemical mimetics for controlled stem cell differentiation into cardiomyocytes / Gary R. Skuse and Kathleen A. Lamkin-Kennard -- 10. Phenotypic analysis of bioactive cells for application in regenerative medicine / Teresa Bora Burnette and Andrew T. Bruce -- 11. Preparation and evaluation of natural scaffold materials for kidney regenerative applications / Monica A. Serban, Toyin A. Knight, and Richard G. Payne -- 12. Rapid production of autologous fibrin hydrogels for cellular encapsulation in organ regeneration / Adelola O. Oseni, Peter E. Butler, and Alexander M. Seifalian -- 13. Electrospinning tubular scaffolds with tissue-like mechanical properties and biomimetic surface features / Scott Rapoport -- 14. Design, fabrication, and preparation of synthetic scaffolds for urologic tissue engineering / Richard G. Payne and Toyin A. Knight -- 15. Characterization of a PGA-based scaffold for use in a tissue-engineered neo-urinary conduit / Toyin A. Knight and Richard G. Payne -- 16. Migration assay to evaluate cellular interactions with biomaterials for tissue engineering/regenerative medicine applications / Kelly I. Guthrie, Namrata Sangha, Christopher W. Genheimer, Joydeep Basu, and John W. Ludlow -- 17. Care of rodent models used for preclinical evaluation of tissue-engineered/regenerative medicine product candidates / Kim L. Mihalko -- 18. Bioreactor design considerations for hollow organs / Jeff Fish, Craig Halberstadt, Darell W. McCoy and Neil Robbins -- 19. Construction of a multicoaxial hollow fiber bioreactor / Randall McClelland, Katherine Tech, and Jeffrey M. Macdonald -- 20. Isolation of human cadaveric pancreatic islets for clinical transplantation / Craig Halberstadt, Deana Williams, and Paul Gores -- 21. Microencapsulation of pancreatic islets for use in a bioartificial pancreas / Emmanuel C. Opara, John P. McQuilling, and Alan C. Farney -- 22. Bioengineered skin substitutes / Pedro Lei, Hui You, and Stelios T. Andreadis -- 23. Formulation of selected renal cells for implantation into a kidney / Craig Halberstadt, Neil Robbins, Darrell W. McCoy, Kelly I. Guthrie, Andrew T. Bruce, Toyin A. Knight and Richard G. Payne -- 24. Human liver bioengineering using a whole liver decellularized bioscaffold / Pedro M. Baptista, Dipen Vyas, Emma Moran, Zhan Wang and Shay Soker -- 25. A "living bioreactor" for the production of tissue-engineered small intestine / Daniel E. Levin, Frederic G. Sala, Erik R. Barthel, Allison L. Speer, Xiaogang Hou, Yasuhiro Torshima and Tracy C. Grikscheit -- 26. Tissue engineering of esophagus and small intestine in rodent injury models / Joydeep Basu, Kim L. Mihalko, Elias A. Rivera, Kelly I. Guthrie, Christopher W. Genheimer, Namrata Sangha and John W. Ludlow -- 27. Scanning electron microscopy evaluation of endothelialized tissue-engineered constructs / Sandra L. Johnson -- 28. Genotypic and phenotypic analysis of in vivo tissue regeneration in an animal model / Christopher W. Genheimer -- 29. Histological evaluation of tissue regeneration using biodegradable scaffold seeded by autologous cells for tubular/hollow organ applications / Elias A. Rivera and Manuel J. Jayo.
  • 2002 Springer Protocols
    edited by Bing-Yuan Chen and Harry W. Janes.
    A short history of the polymerase chain reaction /; J.M. Bartlett and D. Stirling --; Pcr patent issues /; P. Carroll and D. Casimir --; Equipping and establishing a pcr laboratory /; S. McDonagh --; Quality control in pcr /; D. Stirling --; Extraction of nucleic acid templates /; J.M. Bartlett --; Extraction of DNA from whole blood /; J.M. Bartlett and A. White --; DNA extraction from tissue /; H. Pearson and D. Stirling --; Extraction of DNA from microdissected archival tissues /; J.J. Going --; Rna extraction from blood /; H. Pearson --; Rna extraction from frozen tissue /; J.M. Bartlett --; Rna extraction from tissue sections /; H. Pearson --; Dual DNA/rna extraction /; D. Stirling and J.M. Bartlett --; DNA extraction from fungi, yeast, and bacteria /; D. Stirling --; Isolation of rna viruses from biological materials /; S. McDonagh --; Extraction of ancient DNA /; W.M. Schmerer --; DNA extraction from plasma and serum /; D. Stirling --; Technical notes for the detection of nucleic acids /; J.M. Bartlett --; Technical notes for the recovery and purification of pcr products from acrylamide gels /; D. Stirling --; Pcr primer design /; D.L. Hyndman and M. Mitsuhashi --; Optimization of polymerase chain reactions /; H. Grunenwald --; Subcycling pcr for long-distance amplifications of regions with high and low guanine-cystine content: Amplification of the intron 22 inversion of the fviii gene /; D. Stirling --; Rapid amplification of cdna ends /; X. Wang and W.S. Young, 3rd --; Randomly amplified polymorphic DNA fingerprinting: The basics /; R.S. Dassanayake and L.P. Samaranayake --; Microsphere-based single nucleotide polymorphism genotyping /; M.A. Iannone [and others] --; Ligase chain reaction /; W.H. Benjamin, Jr., K.R. Smith and K.B. Waites --; Nested rt-pcr in a single closed tube /; A. Olmos [and others] --; Direct pcr from serum: Application to viral genome detection /; K. Abe --; Long pcr amplification of large fragments of viral genomes: A technical overview /; R. Tellier [and others] --; Long pcr methodology /; R. Tellier [and others] --; Qualitative and quantitative pcr: A technical overview /; D. Stirling --; Ultrasensitive pcr detection of tumor cells in myeloma /; F.W. Cremer and M. Moos --; Ultrasensitive quantitative pcr to detect rna viruses /; S. McDonagh --; Quantitative pcr for camp ri alpha mrna: Use of site-directed mutation and pcr mimics /; J.M. Bartlett --; Quantitation of multiple rna species /; R. Kerr --; Differential display: A technical overview /; J.M. Bartlett --; Au-differential display, reproducibility of a differential mrna display targeted to au motifs /; O. Dominguez [and others] --; Pcr fluorescence differential display /; K. Khalturin, S. Kuznetsov and T.C. Bosch --; Microarray analysis using rna arbitrarily primed pcr /; S. Ringquist [and others] --; Oligonucleotide arrays for genotyping: Enzymatic methods for typing single nucleotide polymorphisms and short tandem repeats /; S. Case-Green, C. Pritchard and E. Southern --; Serial analysis of gene expression /; K.A. Oien --; Mutation and polymorphism detection: A technical overview /; J. Edwards and J.M. Bartlett --; Combining multiplex and touchdown pcr for microsatellite analysis /; K. Rithidech and J.J. Dunn --; Detection of microsatellite instability and loss of heterozygosity using DNA extracted from formalin-fixed paraffin-embedded tumor material by fluorescence-based multiplex microsatellite pcr /; J. Edwards and J.M. Bartlett --; Reduction of shadow band synthesis during pcr amplification of repetitive sequences from modern and ancient DNA /; W.M. Schmerer --; Degenerate oligonucleotide-primed pcr /; M. Aubele and J. Smida --; Mutation detection using rt-pcr-rflp /; H. Nakashima, M. Akahoshi and Y. Tanaka --; Multiplex amplification refractory mutation system for the detection of prothrombotic polymorphisms /; D. Stirling --; Pcr-sscp analysis of polymorphism: A simple and sensitive method for detecting differences between short segments of DNA /; M. Han and M.A. Robinson --; Sequencing: A technical overview /; D. Stirling --; Preparation and direct automated cycle sequencing of pcr products /; S.E. Daniels --; Nonradioactive pcr sequencing using digoxigenin /; S. Kosel [and others] --; Direct sequencing by thermal asymmetric pcr /; G.R. Mazars and C. Theillet --; Analysis of nucleotide sequence variations by solid-phase minisequencing /; A. Suomalainen and A.C. Syvanen --; Direct sequencing with highly degenerate and inosine-containing primers /; Z. Shen [and others] --; Determination of unknown genomic sequences without cloning /; J.P. Quivy and P.B. Becker --; Cloning pcr products for sequencing in m13 vectors /; D. Walsh --; DNA rescue by the vectorette method /; M.A. McAleer, A.J. Coffey and I. Dunham --; Technical notes for sequencing difficult templates /; D. Stirling --; Pcr-based detection of nucleic acids in chromosomes, cells, and tissues: Technical considerations on prins and in situ pcr and comparison with in situ hybridization /; E.J. Speel, F.C. Ramaekers and A.H. Hopman --; Cycling primed in situ amplification /; J.H. Bull and L. Paskins --; Direct and indirect in situ pcr /; K.H. Wiedorn and T. Goldmann --; Reverse transcriptase in situ pcr: New methods in cellular interrogation /; M. Gilchrist and A.D. Befus --; Primed in situ nucleic acid labeling combined with immunocytochemistry to simultaneously localize DNA and proteins in cells and chromosomes /; E.J. Speel, F.C. Ramaekers and A.H. Hopman --; Cloning and mutagenesis: A technical overview /; H. Pearson and D. Stirling --; Using t4 DNA polymerase to generate clonable pcr products /; K. Wang --; A t-linker strategy for modification and directional cloning of pcr products /; R.M. Horton, R. Raju and B.M. Conti-Fine --; Cloning gene family members using pcr with degenerate oligonucleotide primers /; G.M. Preston --; Cdna libraries from a low amount of cells /; P. Ravassard [and others] --; Creation of chimeric junctions, deletions, and insertions by pcr /; G. Pont-Kingdon --; Recombination and site-directed mutagenesis using recombination pcr /; D.H. Jones and S.C. Winistorfer --; Megaprimer pcr: Application in mutagenesis and gene fusion /; E. Burke and S. Barik.
  • 2005 CRCnetBASE
    edited by Sachdev S. Sidhu.
  • 2009 Springer
    edited by Carlos A. Guzman, Giora Z. Feuerstein.
    Translational medicine: a paradigm shift in modern drug discovery and development: the role of biomarkers / Mark Day, J. Lynn Rutkowski, and Giora Z. Feuerstein -- Natural products in drug discovery: present status and perspectives / Gabriella Molinari -- Protein pharmaceuticals: discovery and preclinical development / Davinder S. Gill -- The role of nanobiotechnology in drug discovery / Kewal K. Jain -- Conotoxin venom peptide therapeutics / Richard J. Lewis -- Shark novel antigen receptors: the next generation of biologic therapeutics? / Caroline Barelle, Davinder Gill, and Keith Charlton -- Immune interventions of human diseases through toll-like receptors / Cevayir Coban, Ken J. Ishii, and Shizuo Akira -- Genome-based vaccine development: a short cut for the future / Danilo Gomes Moriel ... [et al.] -- The antigenome: from protein subunit vaccines to antibody treatments of bacterial infections? / Carmen Giefing, Eszter Nagy, and Alexander von Gabain -- HSV as a vector in vaccine development and gene therapy / Peggy Marconi ... [et al.] -- Virus-like particles as a vaccine delivery system: myths and facts / Polly Roy and Rob Noad -- Applications of bacterial ghosts in biomedicine / Petra Lubitz, Ulrike Beate Mayr, and Werner Lubitz -- Immune modulators with defined molecular targets: cornerstone to optimize rational vaccine design / Thomas Ebensen and Carlos A. Guzmøn -- Innovative approaches to develop prophylactic and therapeutic vaccines against HIV/AIDS / Aurelio Cafaro ... [et al.] -- New strategies to overcome the drawbacks of currently available flu vaccines / Epifanio Fichera ... [et al.].
    Also available: Print – 2009
  • 2006 CRCnetBASE
    edited by Michael J. Groves.
  • 2006 Springer
    edited by Jan J. Dubowski and Stoyan Tanev.
  • 2006 Wiley
    Richard S. Quimby.
    Part 1. Propagation of light -- ch. 1. Overview -- ch. 2. Review of optics -- ch. 3. Planar waveguides -- ch. 4. Cylindrical waveguides -- ch. 5. Losses in optical fibers -- ch. 6. Dispersion in optical fibers -- ch. 7. Fiber connections and diagnostics -- ch. 8. Photonic crystal optics -- ch. 9. Nonlinear optics -- Part 2. Generation and Detection of Light -- ch. 10. Review of semiconductor physics -- ch. 11. Light sources -- ch. 12. Light source to waveguide coupling efficiency -- ch. 13. Optical detectors -- ch. 14. Photodiode detectors -- Part 3. Laser light -- ch. 15. Lasers and coherent light -- ch. 16. Optical resonators -- ch. 17. Guassian beam optics -- ch. 18. Stimulated emission and optical gain -- ch. 19. Optical amplifiers -- ch. 20. Laser oscillation -- ch. 21. CW laser characteristics -- ch. 22. Pulsed lasers -- ch. 23. Survey of laser types -- Part 4. Light-based communications -- ch. 24. Optical communications -- Appendix A. Solid angle and the brightness theorem -- Appendix B. Fourier synthesis and the uncertainty relation.
  • 2011 CRCnetBASE
    edited by Christine E. Pullar.
    Measuring endogenous electric fields / Richard Nuccitelli -- Investigation systems to study the biological effects of weak physiological electric fields / Francis X. Hart -- Endogenous bioelectric signals as morphogenetic controls of development, regeneration, and neoplasm / Michael Levin -- Stem cell physiological responses to noninvasive electrical stimulation / Igor Titushkin ... [et al.] -- Electrical signals control corneal epithelial cell physiology and wound repair / Colin D. McCaig -- Physiological electric fields can direct keratinocyte migration and promote healing in chronic wounds / Christine E. Pullar -- Electrical control of angiogenesis / Entong Wang ... [et al.] -- Inflammatory cell electrotaxis / Francis Lin and Christine E. Pullar -- Effects of DC electric fields on migration of cells of the musculoskeletal system / Najmuddin J. Gunja, Clark T. Hung, and J. Chlöe Bulinski -- Neuronal growth cone guidance by physiological DC electric fields / Ann M. Rajnicek -- Can applied voltages be used to produce spinal cord regeneration and recovery in humans? / Richard Ben Borgens -- Bioelectricty of cancer : voltage-gated ion channels and direct-current electric fields / Mustafa B. A. Djamgoz.
  • 2007 Springer Protocols
    edited by Neil Willey.
  • 2016 Springer Protocols
    edited by David Edwards.
    Using GenBank / Eric W. Sayers and Ilene Karsch-Mizrachi -- UniProtKB/Swiss-Prot, the manually annotated section of the UniProt knowledgebase : how to use the entry view / Emmanuel Boutet ... [et al.] -- KEGG bioinformatics resource for plant genomics and metabolomics / Minoru Kanehisa -- Plant pathway databases / Pankaj Jaiswal and Björn Usadel -- Plant ontology : a tool for plant genomics / Laurel Cooper and Pankaj Jaiswal -- Ensembl plants : integrating tools for visualizing, mining, and analyzing plant genomics data / Dan Bolser ... [et al.] -- Gramene : a resource for comparative analysis of plants genomes and pathways / Marcela Karey Tello-Ruiz ... [et al.] -- PGSB/MIPS plant genome information resources and concepts for the analysis of complex grass genomes / Manuel Spannagl ... [et al.] -- MaizeGDB : the maize genetics and genomics database / Lisa Harper ... [et al.] -- WheatGenome.info : a resource for wheat genomics resource / Kaitao Lai -- User guidelines for the brassica database : BRAD / Xiaobo Wang, Feng Cheng, and Xiaowu Wang -- TAG sequence identification of genomic regions using TAGdb / Pradeep Ruperao -- Short read alignment using SOAP2 / Bhavna Hurgobin -- Tablet : visualizing next-generation sequence assemblies and mappings / Iain Milne ... [et al.] -- Analysis of genotyping-by-sequencing (GBS) data / Sateesh Kagale ... [et al.] -- Skim-based genotyping by sequencing using a double haploid population to call SNPs, infer gene conversions, and improve genome assemblies / Philipp Emanuel Bayer -- Finding and characterizing repeats in plant genomes / Jacques Nicolas, Pierre Peterlongo, and Sébastien Tempel -- Analysis of RNA-Seq data using TopHat and cufflinks / Sreya Ghosh and Chon-Kit Kenneth Chan.
  • 2007 Springer Protocols
    edited by David Edwards.
    The EMBL nucleotide sequence and genome reviews databases / Peter Sterk ... [et al.] -- Using GenBank / David Wheeler -- A collection of plant-specific genomic data and resources at NCBI / Tatiana Tatusova, Brian Smith-White, and James Ostell -- UniProtKB/Swiss-Prot / Emmanuel Boutet ... [et al.] -- Plant database resources at The Institute for Genomic Research / Agnes P. Chan... [et al.] -- MIPS plant genome information resources / Manuel Spannagl ...[et al.] -- HarvEST / Timothy J. Close ... [et al.] -- The TAIR database / Rebecca L. Poole -- AtEnsEMBL / Nick James ... [et al.] -- Accessing integrated Brasica genetic and genomic data using the BASC server / Christopher G. Love and David Edwards -- Leveraging model legume information to find candidate genes for soybean sudden death syndrome using the Legume Information System / Michael D. Gonzales ... [et al.] -- Legume resources : MtDB and Medicago.org / Ernest F. Retzel ... [et al.] -- BGI-RIS V2 / Ximiao He and Jun Wang -- GrainGenes / Helen O'Sullivan -- Gramene / Doreen Ware -- MaizGDB / Carolyn J. Lawrence -- BarleyBase/PLEXdb / Roger P. Wise ... [et al.] -- Reaping the benefits of SAGE / Stephen J. Robinson ... [et al.] -- Methods for analysis of gene expression in plants using MPSS / Kan Nobuta, Kalyan Vemaraju, and Blake C. Meyers -- Metabolomics data analysis, visualization, and integration / Lloyd W. Sumner, Ewa Urbanczyk-Wochniak, and Corey D. Broeckling -- KEGG bioinformatics resource for plant genomics research / Ali Masoudi-Nejad ... [et al.] -- International Crop Information System for germplasms data management / Arllet Portugal ... [et al.] -- Automated discovery of single nucleotide polymorphism and simple sequence repeat molecular genetic markers / Jacqueline Batley, Erica Jewell, and David Edwards -- Methods for gene ontology annotation / Emily Dimmer ... [et al.] -- Gene structure annotation at PlantGDB / Volker Brendel -- An introduction to BioPerl / Jason E. Stajich.
  • 2011 Springer Protocols
    edited by James A. Birchler.
    Recent advances in plant transformation -- Engineering the plastid genome of nicotiana sylvestris, a diploid model species for plastid genetics -- Homologous recombination in plants : An antireview -- Chromosome painting for plant biotechnology -- Plant B chromosomes -- Telomere truncation in plants -- Engineered plant minichromosomes -- Method for bxb1-mediated site-specific integration in planta -- Targeted mutagenesis in arabidopsis using zinc-finger nucleases -- Vectors and methods for hairpin RNA and artificial microRNA-mediated gene silencing in plants -- Recombinant protein expression in nicotiana -- Chromosome analysis and sorting using flow cytometry -- Super-stretched pachytene chromosomes for plant molecular cytogenetic mapping -- Cytological dissection of the triticeae chromosomes by the gametocidal system -- Development and use of oat-maize chromosome additions and radiation hybrids -- Enhancer trapping in plants -- Chromatin beacons : Global sampling of chromatin physical properties using chromatin charting lines -- Transposable elements as catalysts for chromosome rearrangements.
  • 2006 Springer
    edited by S. Dutta Gupta and Yasuomi Ibaraki.
  • 2011 Future Med
    editor, Franco M. Buonaguro.
    Plant-derived vaccines : technologies & applications / Franco M. Buonaguro -- Patents and molecular farming / Pascal M.W. Drake & Harry Thangaraj -- In planta production of recombinant and indigenous adjuvants / Antonio Granell, Asun Fernandez-del-Carmen & Diego Orzáez -- Rapid and high-yield production of immunotherapeutic plant-made antibodies / Cristina Capodicasa, Marcello Donini, Maria Elena Villani & Eugenio Benvenuto -- Vaccine peptide display on recombinant tobacco mosaic virus particles / Tatiana V. Komarova, Igor V. Petrunia & Yuri L. Dorokhov -- Plastid transformation as a tool for plant-based production of vaccines and therapeutic proteins / Paolo Lenzi, Nunzia Scotti, Pal Maliga & Teodoro Cardi -- Prophylactic and therapeutic HPV vaccines from plants / Edward P. Rybicki, Colomba Giorgi & Rosella Franconi -- Plant-derived anti-HIV-1 proteins / Nunzia Scotti, Luigi Buonaguro, Maria Lina Tornesello, Teodoro Cardi & Franco Maria Buonaguro -- Plant-based hepatitis B vaccines / Sergei N. Shchelkunov & Galina A. Shchelkunova -- Influenza vaccines : new perspectives from plants / Chiara Lico, Giampaolo Buriani, Floriana Capuano, Eugenio Benvenuto & Selene Baschieri -- Plant-made mucosal vaccines / Rurick K. Salyaev, Maria Manuela Rigano & Natalya I. Rekoslavskaya -- Current status of plant-made veterinary vaccines / Assunta Pelosi, Claire Penney, Huai-Yian Ling & Amanda M. Walmsley.
  • 2009 Springer
    Alexander V. Karasev, editor.
    Plant vaccines: an immunological perspective / D.C. Hooper -- Display of peptides on the surface of tobacco mosaic virus particles / M.L. Smith ... [et al.] -- Chloroplast-derived vaccine antigens and biopharmaceuticals: expression, folding, assembly and functionality / S. Chebolu and H. Daniell -- Production of antibodies in plants: approaches and perspectives / K. Ko, R. Brodzik and Z. Steplewski -- Plant production of veterinary vaccines and therapeutics / R.W. Hammond and L.G. Nemchinov -- Plant-based oral vaccines: results of human trials / C.O. Tacket.
    Also available: Print – 2009
  • 2005 CRCnetBASE
    [edited by] Severian Dumitriu.
  • 2010 CRCnetBASE
    edited by Taosheng Chen.
  • 2014 ScienceDirect
    edited by Jose Cibelli [and six others].
    Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species-including mice, sheep, cattle, and non-mammals-is considered as well.
  • 2011 ScienceDirect
    2011 ClinicalKey
    [edited by] Anthony Atala ... [et al.].
    Chapter 1. Molecular Organization of Cells / Jon D. Ahlstrom -- Chapter 2. Cell-ECM Interactions in Repair and Regeneration / M. Petreaca, M. Martins-Green -- Chapter 3. Mechanisms of Blastema Formation in Regenerating Amphibian Limbs / David L. Stocum, Nandini Rao -- Chapter 4. The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells and iPS Cells / Harvir Singh, Ali H. Brivanlou -- Chapter 5. How Cells Change their Phenotype / Caroline Beth Sangan, David Tosh -- Chapter 6. Scarless Wound Healing / Allison Nauta, Barrett Larson, Michael T. Longaker, H. Peter Lorenz -- Chapter 7. Somatic Cloning and Epigenetic Reprogramming in Mammals / Heiner Niemann, Wilfried A. Kues, Andrea Lucas-Hahn, Joseph W. Carnwath -- Chapter 8. Engineered Proteins for Controlling Gene Expression / Charles A. Gersbach -- Chapter 9. Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine / Junfeng Ji, Bonan Zhong, Mickie Bhatia -- Chapter 10. Embryonic Stem Cells: Derivation and Properties / Junying Yu, James A. Thomson -- Chapter 11. Alternative Sources of Human Embryonic Stem Cells / Svetlana Gavrilov, Virginia E. Papaioannou, Donald W. Landry -- Chapter 12. Stem Cells from Amniotic Fluid / Mara Cananzi, Anthony Atala, Paolo de Coppi -- Chapter 13. Induced Pluripotent Stem Cells / Keisuke Okita, Shinya Yamanaka -- Chapter 14. MSCs in Regenerative Medicine / Arnold I. Caplan -- Chapter 15. Multipotent Adult Progenitor Cells / Philip Roelandt, Catherine M. Verfaillie -- Chapter 16. Hematopoietic Stem Cell Properties, Markers, and Therapeutics / Kuanyin K. Lin, Grant A. Challen, Margaret A. Goodell -- Chapter 17. Mesenchymal Stem Cells / Zulma Gazit, Gadi Pelled, Dima Sheyn, Nadav Kimelman, Dan Gazit -- Chapter 18. Cell Therapy of Liver Disease: From Hepatocytes to Stem Cells / Stephen C. Strom, Ewa C.S. Ellis -- Chapter 19. Cardiac Stem Cells: Biology and Therapeutic Applications / Sarah Selem, Konstantinos E. Hatzistergos, Joshua M. Hare -- Chapter 20. Skeletal Muscle Stem Cells / Benjamin D. Cosgrove, Helen M. Blau -- Chapter 21. Stem Cells Derived from Fat / Adam J. Katz, Alexander F. Mericli -- Chapter 22. Peripheral Blood Stem Cells / Zhan Wang, Gunter Schuch, J. Koudy Williams, Shay Soker -- Chapter 23. Islet Cell Therapy and Pancreatic Stem Cells / Juan Domínguez-Bendala, Antonello Pileggi, Camillo Ricordi -- Chapter 24. Regenerative Medicine for Diseases of the Retina / Deepak A. Lamba, Thomas A. Reh -- Chapter 25. Somatic Cells: Growth and Expansion Potential of T Lymphocytes / Rita B. Effros -- Chapter 26. Mechanical Determinants of Tissue Development / Jonathan A. Kluge, Gary G. Leisk, David L. Kaplan -- Chapter 27. Morphogenesis of Bone, Morphogenetic Proteins, and Regenerative Medicine / A.H. Reddi -- Chapter 28. Physical Stress as a Factor in Tissue Growth and Remodeling / Joel D. Boerckel, Christopher V. Gemmiti, Yash M. Kolambkar, Blaise D. Porter, Robert E. Guldberg -- Chapter 29. Intelligent Surfaces for Cell-Sheet Engineering / Takanori Iwata, Masayuki Yamato, Teruo Okano -- Chapter 30. Applications of Nanotechnology for Regenerative Medicine / Benjamin S. Harrison, Sirinrath Sirivisoot -- Chapter 31. Design Principles in Biomaterials and Scaffolds / Hyukjin Lee, Hyun Jung Chung, Tae Gwan Park -- Chapter 32. Natural Origin Materials for Bone Tissue Engineering - Properties, Processing, and Performance / V.M. Correlo, J.M. Oliveira, J.F. Mano, N.M. Neves, R.L. Reis -- Chapter 33. Synthetic Polymers / M.C. Hacker, A.G. Mikos -- Chapter 34. Biological Scaffolds for Regenerative Medicine / Alexander Huber, Stephen F. Badylak -- Chapter 35. Hydrogels in Regenerative Medicine / Justin M. Saul, David F. Williams -- Chapter 36. Surface Modification of Biomaterials / Andrés J. García -- Chapter 37. Histogenesis in Three-dimensional Scaffolds / Melissa K. McHale, Nicole M. Bergmann, Jennifer L. West -- Chapter 38. Biocompatibility and Bioresponse to Biomaterials / James M. Anderson -- Chapter 39. Designing Tunable Artificial Matrices for Stem Cell Culture / Elizabeth F. Irwin, Jacob F. Pollock, David V. Schaffer, Kevin E. Healy -- Chapter 40. Biomineralization and Bone Regeneration / Jiang Hu, Xiaohua Liu, Peter X. Ma -- Chapter 41. Cell Therapy for Blood Substitutes / Shi-Jiang Lu, Qiang Feng, Feng Li, Erin A. Kimbrel, Robert Lanza -- Chapter 42. Articular Cartilage / Lily Jeng, Francois Ng kee Kwong, Myron Spector -- Chapter 43. Myoblast Transplantation in Skeletal Muscles / Daniel Skuk, Jacques P. Tremblay -- Chapter 44. Clinical Islet Transplantation / Juliet A. Emamaullee, Michael McCall, A.M. James Shapiro -- Chapter 45. Fetal Tissues / Ryan P. Dorin, Chester J. Koh -- Chapter 46. Engineering of Large Diameter Vessels / Masood A. Machingal, Saami K. Yazdani, George J. Christ -- Chapter 47. Engineering of Small-Diameter Vessels / Brett C. Isenberg, Chrysanthi Williams, Robert T. Tranquillo -- Chapter 48. Cardiac Tissue / Milica Radisic, Michael V. Sefton -- Chapter 49. Regenerative Medicine in the Cornea / May Griffith, Per Fagerholm, Neil Lagali, Malcolm A. Latorre, Joanne Hackett, Heather Sheardown -- Chapter 50. Alimentary Tract / Richard M. Day -- Chapter 51. Extracorporeal Renal Replacement / Kimberly A. Johnston, H. David Humes -- Chapter 52. Tissue Engineering of the Reproductive System / Stefano Da Sacco, Laura Perin, Roger E. De Filippo -- Chapter 53. Cartilage Tissue Engineering / Qiongyu Guo, Jennifer H. Elisseeff -- Chapter 54. Functional Tissue Engineering of Ligament and Tendon Injuries / Savio L.-Y. Woo, Alejandro J. Almarza, Sinan Karaoglu, Rui Liang, Matthew B. Fisher -- Chapter 55. Central Nervous System / Brian G. Ballios, M. Douglas Baumann, Michael J. Cooke, Molly S. Shoichet -- Chapter 56. Peripheral Nerve Regeneration / Mahesh C. Dodla, Vivek J. Mukhatyar, Ravi V. Bellamkonda -- Chapter 57. Tissue Engineering of Skin / Fiona Wood -- Chapter 58. Regenerative Medicine of the Respiratory Tract / Martin A. Birchall, Sam Janes, Paolo Macchiarini -- Chapter 59. The Digit: Engineering of Phalanges and Small Joints / Makoto Komura, Jaehyun Kim, Anthony Atala, James J. Yoo, Sang Jin Lee -- Chapter 60. Intracorporeal Kidney Support / Jae Hyun Bae, Tamer Aboushwareb, Anthony Atala, James J. Yoo -- Chapter 61. Ethical Considerations / Ronald M. Green -- Chapter 62. US Stem Cell Research Policy / Josephine Johnston -- Chapter 63. Overview of the FDA Regulatory Process / Kevin J. Whittlesey, Mark H. Lee, Jiyoung M. Dang, Maegen Colehour, Judith Arcidiacono, Ellen Lazarus, David S. Kaplan, Donald Fink, Charles N. Durfor, Ashok Batra, Stephen L. Hilbert, Deborah Lavoie Grayeski, Richard McFarland, Celia Witten.
  • 2014 ScienceDirect
    edited by Robert Lanza, Robert Langer, Joseph Vacanti.
  • 2007 Springer
    Bob van Hilten (editor), Bart Nuttin (editor).
  • 2007 CRCnetBASE
    edited by Abhinav A. Shukla, Mark R. Etzel, Shishir Gadam.
    Harvest of a therapeutic protein product from high cell density fermentation broths : principles and case study / Elisabeth Russell, Alice Wang, and Anurag S. Rathore -- Expanded bed adsorption for capture from crude solution / Alan Sonnenfeld and Jorg Thommes -- Product recovery by high-gradient magnetic fishing / Matthias Franzreb ... [et al.] -- Protein refolding and scale up / Cynthia Cowgill, Asuman G. Ozturk, and Richard St. John -- Bulk protein crystallization, principles and methods / Mark R. Etzel -- Modes of preparative chromatography / Abhinav A. Shukla and Yinges Yigzaw -- Screening of chromatographic stationary phases / Abhinav A. Shukla and Xuejun Sean Han -- A priori prediction of chromatographic separations from protein structure data / Asif Ladiwala, Curt M. Breneman, and Steven M. Cramer -- Membrane chromatography : analysis of breakthrough curves and viral clearance / Mark R. Etzel and William T. Riordan -- Ultrafiltration process design and implementation / Herb Lutz and Bala Raghunath -- Virus filtration process design and implementation / Michael W. Phillips ... [et al.] -- Product recovery from transgenic sources / Chenming (Mike) Zhang and Kevin E. Van Cott -- Analytical strategy for biopharmaceutical development / Drew N. Kelner and Mahesh K. Bhalgat -- Evaluation of viral clearance in purification processes / Amitava Kundu and Karl Reindel -- Advances in viral clearance / Kurt Brorson -- Protein A affinity chromatography for capture and purification of monoclonal antibodies and Fc-fusion proteins: practical considerations for process development / Sanchayita Ghose, Thomas McNerney, and Brian Hubbard -- Polishing methods for monoclonal IgG purification / Pete Gagnon -- Making changes to a biopharmaceutical manufacturing process during development and commercial manufacturing : the REMICADE story / Peter W. Wojciechowski ... [et al.] -- Linear scale-up of ultrafiltration of high viscosity process streams / Christopher Daniels ... [et al.] -- A membrane chromatography application : a rapid, high capacity gene therapy vector purification tool / Ajay R. Lajmi, Robert Kutner, and Jakob Reiser.
  • 2005 CRCnetBASE
    edited by Anurag Singh Rathore, Gail Sofer.
  • 2007 Springer
    Valentino J. Stella ... [et al.], editors.
  • 2006 CRCnetBASE
    William L. Hochfeld.
  • 2013 Springer
    Eugene Rosenberg (editor-in-chief), Edward F. DeLong...[et al.] (eds.).
    Organic Acid and Solvent Production: Acetic, Lactic, Gluconic, Succinic, and Polyhydroxyalkanoic Acids / Palmer Rogers, Jiann-Shin Chen, Mary Jo Zidwick -- Organic Acid and Solvent Production: Butanol, Acetone, and Isopropanol; 1,3- and 1,2-Propanediol Production; and 2,3-Butanediol Production / Jiann-Shin Chen, Mary Jo Zidwick, Palmer Rogers -- Organic Acid and Solvent Production: Propionic and Butyric Acids and Ethanol / Mary Jo Zidwick, Jiann-Shin Chen, Palmer Rogers -- Amino Acid Production / Hidehiko Kumagai -- Microbial Exopolysaccharides / Avinash Mishra, Dr. Bhavanath Jha -- Bacterial Enzymes / Prof. Wim J. Quax -- Diversity and Biotechnological Applications of Prokaryotic Enzymes / Alane Beatriz Vermelho, Eliane Ferreira Noronha, Edivaldo Ximenes Ferreira Filho -- Bacteria in Food and Beverage Production / Dr. Michael P. Doyle, Larry R. Steenson, Jianghong Meng -- Bacterial Pharmaceutical Products / Giancarlo Lancini, Dr. Arnold L. Demain -- Biosurfactants / Dr. Eugene Rosenberg, Eliora Z. Ron -- Bioremediation / Ronald L. Crawford, Dr. Eugene Rosenberg -- Biodeterioration / Ji-Dong Gu, Ralph Mitchell -- Microbial Biofilms / Dirk De Beer, Paul Stoodley -- Biofuels / Stefano Freguia, Bernardino Virdis, Dr. Korneel Rabaey -- The Metabolic Pathways of Biodegradation / Lawrence P. Wackett.
  • 2013 Springer
    Abdulhameed Sabu, Anu Augustine, editors.
    The book entitled "Prospects in Bioscience: Addressing the issues" is a collection of selected research papers presented at the International Conference on Advances in Biological Sciences (ICABS) organized by the Department of Biotechnology and Microbiology and the Inter University Centre for Bioscience, Kannur University, Kerala, India. ICABS witnessed a unique spectrum of Scientific Programmes on the most recent and exciting developments in modern biology. The conference displayed the numerous breakthroughs and significant developments in the important areas of modern biology and their relevance to the welfare of global society. The Book contains 50 well written chapters, each one discussing scientifically organized findings of original research work done in reputed laboratories. Needless to say, they deal with advances in various disciplines of modern biology including Cell and Molecular Biology, Structural Biology, Industrial and Environmental Biotechnology, Food and Agricultural Biotechnology and Medical Biotechnology. As the title rightly indicates, the chapters project the prospects in the respective areas and the issues in them. Specific issues discussed in the book includes development of transgenic plants, bioremediation of toxic industrial effluents, biotransformation for novel antibiotics, biofertilizer development, molecular drug designing and structure elucidation, molecular identification of pathogens, production of anti microbials, biocontrol agents and bioactive molecules, cancer biology, plant breeding and hybrid seed production etc. The book with its contents spreading across the vast arena of modern biology is expected to cater to the need of researchers, technologists and students.
  • 2014 Springer Protocols
    edited by Nikolaos E. Labrou.
    Protein Purification: An Overview -- Establishment of a Design Space for Biopharmaceutical Purification Processes Using DoE -- High Throughput Process Development: I. Process Chromatography -- High Throughput Process Development: II. Membrane Chromatography -- Media Selection in Ion Exchange Chromatography in a Single Microplate -- High Throughput Screening of Dye-Ligands for Chromatography -- Measurement of Uptake Curves and Adsorption Isotherms by Automated Microscale Chromatography Pipette Tips -- Recovery of Recombinant Proteins from Plants Using Aqueous Two-Phase Partitioning Systems: An Outline -- Aqueous Two-Phase Systems Strategies for the Recovery of Proteins from Plants -- Aqueous Two Phase Assisted Precipitation of Proteins: A Platform for Isolation of Process Related Impurities from Therapeutic Proteins -- Simultaneous Purification and Refolding of Proteins by Affinity Precipitation and Macro-(Affinity Ligand) Facilitated Three Phase Partitioning (MLFTPP) -- Co-Expression and Co-Purification of Antigen-Antibody Complexes in Bacterial Cytoplasm and Periplasm -- Immunoglobulin Purification by Caprylic Acid -- Affinity Tags in Protein Purification and Peptide Enrichment: An Overview -- Expression and Purification of Large Active GST Fusion Enzymes -- Synthetic Ligand Affinity Chromatography. Purification of Human Serum Albumin and Related Fusion Proteins -- Zbasic -- A Purification Tag for Selective Ion-Exchange Recovery -- An Orthogonal Fusion Tag for Efficient Protein Purification -- Phage Display of Engineered Binding Proteins -- Biomimetic Affinity Ligands for Protein Purification -- Synthesis and Application of Dye-Ligand Affinity Adsorbents -- Peptide Affinity Chromatography Based on Combinatorial Strategies for Protein Purification -- Affinity Chromatography of Proteins on Monolithic Columns -- Sample Displacement Batch Chromatography of Proteins -- Analysis of Host-Cell Proteins in Biotherapeutic Proteins by LC/MS Approaches -- Preparation of Monolithic Affinity Media for Nano-Liquid Chromatography Applications -- Proteomic Analysis of Complex Protein Samples by MALDI TOF Mass Spectrometry -- Modern Bioanalysis of Proteins by Electrophoretic Techniques -- Protein Structure Validation and Analysis with X-Ray Crystallography -- Measuring Binding Constants of His-Tagged Proteins using Affinity Chromatography and Ni-NTA Immobilized Enzymes -- Stabilization of Therapeutic Proteins in Aqueous Solutions and Freeze-Dried Solids: An Overview -- Stabilization of Protein by Freeze-Drying in the Presence of Trehalose: A Case Study of Tubulin -- G Protein-Coupled Receptor Expression and Purification.- (Hyper)thermophilic Enzymes: Production and Purification -- Affinity Chromatography for Antibody Purification -- Screening and Purification of Recombinant Lignocellulolytic Enzymes -- Purification of PEGylated Proteins, with the Example of PEGylated lysozyme and PEGylated scFv -- One-Step Purification of Glutamate decarboxylase from E. coli Using Aqueous Two Phase System.
  • 2009 Springer
    Caroline Köhrer, Uttam L. RajBhandary (eds.).
    Understanding enzyme mechanism through protein chimeragenesis / N.M. Goodey and S.J. Benkovic -- Chemical protein engineering : synthetic and semisynthetic peptides and proteins / L. Merkel, L. Moroder, and N. Budisa -- Native chemical ligation: Semisynthesis of post-translationally modified proteins and biological probes / E. Vogel Taylor and B. Imperiali -- Chemical methods for mimicking post-translational modifications / S.I. van Kasteren, P. Garnier and B.G. Davis -- Noncanonical amino acids in protein science and engineering / K.E. Beatty and D.A. Tirrell -- Fidelity mechanisms of the aminoacyl-tRNA synthetases / A.P. Mascarenhas ... [et al.] -- Specialized components of the translational machinery for unnatural amino acid mutagenesis : tRNAs, aminoacyl-tRNA synthetases, and ribosomes / C. Köhrer and U.L. RajBhandary -- In vivo studies of receptors and ion channels with unnatural amino acids / D.A. Dougherty -- Synthesis of modified proteins using misacylated tRNAs / S.M. Hecht -- Cell-free synthesis of proteins with unnatural amino acids. The pure system and expansion of the genetic code / I. Hirao, T. Kanamori and T. Ueda -- Engineering nucleobases and polymerases for an expanded genetic alphabet / A.M. Leconte and F.E. Romesberg -- Understanding membrane proteins. How to design inhibitors of transmembrane protein-protein interactions / J.S. Slusky, H. Yin and W.F. DeGrado.
  • 2013 Springer Protocols
    edited by Ming Zhou and Timothy Veenstra.
    Affinity depletion of plasma and serum for mass spectrometry-based proteome analysis / Julian A.J. Jaros ... [et al.] -- Tissue sample preparation for biomarker discovery / Yoshiyuki Suehara, Daisuke Kubota, and Tsuyoshi Saito -- Subcellular fractionation for identification of biomarkers : serial detergent extraction by subcellular accessibility and solubility / Sun-II Hwang and David K. Han -- Analysis of secreted proteins / Valeria Severino, Annarita Farina, and Angela Chambery -- Preparation of human cerebrospinal fluid for proteomics biomarker analysis / Timothy J. Waybright -- Proteomic analysis of frozen tissue samples using laser capture microdissection / Sumana Mukherjee ... [et al.] -- Use of formalin-fixed, paraffin-embedded tissue for proteomic biomarker discovery / David B. Krizman and Jon Burrows -- Phosphopeptide enrichment using offline titanium dioxide columns for phosphoproteomics / Li-Rong Yu and Timothy Veenstra -- iTRAQ-labeling for biomarker discovery / Leroi V. DeSouza, Sébastien N. Voisin, and K.W. Michael Siu -- Analysis of glycoproteins for biomarker discovery / Jintang He ... [et al.] -- SILAC in biomarker discovery / Benjamin C. Orsburn -- Trypsin-mediated 18O/16O labeling for biomarker discovery / Xiaoying Ye ... [et al.] -- Two-dimensional SDS-PAGE fractionation of biological samples for biomarker discovery / Thierry Rabilloud and Sarah Triboulet -- Informatics of protein and posttranslational modification detection via shotgun proteomics / Jerry D. Holman, Surendra Dasari, and David L. Tabb -- Quantitation of met tyrosine phosphorylation using MRM-MS / Zhaojing Meng -- Preparation of human serum for prolactin measurement by multiple reaction monitoring mass spectrometry / Timothy J. Waybright ... [et al.] -- Label-free quantitative shotgun proteomics using normalized spectral abundance factors / Karlie A. Neilson ... [et al.] -- Employment of complementary dissociation techniques for body fluid characterization and biomarker discovery / David M. Good and Dorothea Rutishauser -- Phosphopeptide microarrays for comparative proteomic profiling of cellular lysates / Liqian Gao ... [et al.] -- Tissue preparation for MALDI-MS imaging of protein and peptides / Simona Colantonio and Roberta M. Smith -- Plant proteogenomics : from protein extraction to improved gene predictions / Brett Chapman ... [et al.] -- Label-free differential analysis of murine postsynaptic densities / Scott P. Goulding, Michael J. MacCoss, and Christine C. Wu -- Fractionation of peptides by strong cation-exchange liquid chromatography / King C. Chan and Haleem J. Issaq.
  • 2013 Springer Protocols
    edited Maurizio Lambardi, Elif Aylin Ozudogru, Shri Mohan Jain.
    Micropropagation of pear (Pyrus sp.) / Barbara M. Reed [and others] -- In vitro propagation of jojoba / Berta E. Llorente and Nancy M. Apóstolo -- In vitro propagation of olive (Olea europaea L.) by nodal segmentation of elongated shoots / Maurizio Lambardi, Elif Aylin Ozudogru, and Romano Roncasaglia -- Micropropagation systems of feijoa (Acca sellowiana (O. Berg) burret) / Miguel Pedro Guerra [and others] -- Micropropagation of Vaccinium sp. by in vitro axillary shoot proliferation / Wojciech Litwinczuk -- In vitro propagation of peanut (Arachis hypogaea L.) by shoot tip culture / Elif Aylin Ozudogru, Ergun Kaya, and Maurizio Lambardi -- In vitro propagation of persimmon (Diospyros kaki Thunb.) / Edgardo Giordani, Mar Naval, and Carla Benelli -- Micropropagation of Citrus spp. by organogenesis and somatic embryogenesis / Benedetta Chiancone and Maria Antonietta Germanà -- Micropropagation of Prunus species relevant to cherry fruit production / Philippe Druart -- Micropropagation of peach rootstocks and cultivars / Ildikó Balla and Lucienne Mansvelt -- Micropropagation of Rubus and Ribes spp / Ewa Dziedzic and Joanna Jagła -- Somatic embryogenesis for efficient micropropagation of guava (Psidium guajava L.) / Nasim Akhtar -- Micropropagation of chokeberry by in vitro axillary shoot proliferation / Wojciech Litwińczuk -- Micropropagation of Lavandula spp / Sandra Gonçalves and Anabela Romano -- In vitro propagation of Acacia mangium and A. mangium? A. auriculiformis / Olivier Monteuuis, Antoine Galiana, and Doreen Goh -- In vitro propagation of ash (Fraxinus excelsior L.) by somatic embryogenesis / Maurizio Capuana -- Micropropagation of paradise tree (Melia azedarach) by in vitro culture of axillary buds / Luis A. Mroginski and Hebe Y. Rey -- In Vitro Propagation of Hydrangea spp / Barbara Ruffoni, Ermanno Sacco, and Marco Savona -- In vitro propagation of fraser photinia using Azospirillum-mediated root development / Berta E. Llorente and Ezequiel E. Larraburu -- Micropropagation of Helleborus through axillary budding / Margherita Beruto, Serena Viglione, and Alessandro Bisignano -- Micropropagation of Cordyline terminalis / Tui Ray, Prasenjit Saha, and Satyesh C. Roy -- Micropropagation of african violet (Saintpaulia ionantha Wendl.) / Mukund Shukla [and others] -- Micropropagation of Iris sp / Sladana Jevremovic, Zoran Jeknic, and Angelina Subotic -- Micropropagation of Gerbera (Gerbera jamesonii Bolus) / Ghani Minerva and Surinder Kumar -- Micropropagation of onion (Allium cepa L.) from immature inflorescences / Pablo Marinangeli -- In vitro propagation of cauliflower using curd microexplants / Martin Kieffer and Michael P. Fuller -- Micropropagation of Asparagus by in vitro shoot culture / Nataša Štajner -- Micropropagation and cryopreservation of garlic (Allium sativum L.) / E.R. Joachim Keller and Angelika Senula -- Micropropagation of globe artichoke (Cynara cardunculus L. var. scolymus) / Giovanni Iapichino -- In vitro rejuvenation of woody species / Paul E. Read and Christina M. Bavougian -- Encapsulation of in vitro- derived explants : an innovative tool for nurseries / Alvaro Standardi and Maurizio Micheli -- Thermotherapy, chemotherapy, and meristem culture in banana / Ludivine Lassois [and others] -- Agrobacterium-mediated genetic transformation of pineapple (Ananas comosus L., Merr.) / Minal Mhatre -- Protocol for inducing flower color somaclonal variation in Torenia (Torenia fournieri Lind.) / Duong Tan Nhut [and others] -- Production of pathogen-free horticultural crops by cryotherapy of in vitro-grown shoot tips / Chaohong Feng [and others].
  • 2008 Springer
    Rosa Margesin ... [et. al.], editors.
  • 2010 Springer
    Antonella Lanati ; in collaborazione con Luigi Cavenaghi ... [et al.] ; presentazione a cura di Marina Del Bue.
  • 2009 HighWire
    International Commission on Radiation Units and Measurements.
  • 2014 Springer Protocols
    edited by Roberto Biassoni, Laboratorio Medicina Molecolare, Dipartimento Medicina Traslazionale, Instituto Giannina Gaslini, Genova, Italy, Alessandro Raso, Laboratorio U.O.C. Neurochirugia, Instituto Giannina Gaslini, Genova, Italy.
    Twenty years of qPCR: A mature technology? -- Minimum information necessary for quantitative real-time PCR experiments -- Selection of reliable reference genes for RT-qPCR analysis -- Introduction to digital PCR -- mRNA and microRNA purity and integrity: The key to success in expression profiling -- Mediator probe PCR: Detection of real-time PCR by label-free probes and a universal fluorogenic reporter -- Absolute quantification of viral DNA: The quest for perfection -- A multiplex real-time PCR-platform integrated into automated extraction method for the rapid detection and measurement of oncogenic HPV type-specific viral DNA load from cervical samples -- Real-time PCR detection of mycoplasma pneumoniae in the diagnosis of community-acquired pneumonia -- A sensible technique to detect mollicutes impurities in human cells cultured in GMP condition -- Real-time quantification assay to monitor BCR-ABL1 transcripts in chronic myeloid leukemia -- A reliable assay for rapidly defining transplacental metastasis using quantitative PCR -- Circulating cell-free DNA in cancer -- Gene expression analysis by qPCR in clinical kidney transplantation -- Posttranscriptional regulatory networks: From expression profiling to integrative analysis of mRNA and microRNA data -- Clinical applications using digital PCR -- Developing noninvasive diagnosis for single-gene disorders: the role of digital PCR.
  • 2014 Springer Protocols
    edited by Adriana Fontes, Beate Saegesser Santos.
  • 2009
    Michael Nathaniel Cantor.
    Status: Not Checked OutLane Catalog Record
  • 2008 ScienceDirect
    Robert M. Rydzewski.
    The drug discovery business to date -- The drug discovery business to come -- Industrial considerations -- how things get done : the project team -- Project considerations -- Hit generation -- Turning hits into drugs -- Initial properties -- ADME and PK properties -- Toxicity related properties -- A career in drug discovery research.
  • 2013 Springer
    Hossein Baharvand, Nasser Aghdami, editors.
    1. Cell Therapy for Neurodegenerative Disorders / Ilyas Singec -- 2. New Prospects for Neural Stem Cell Therapies of Nervous System Diseases Toward the Establishment of Atypical Ectopic Perivascular Stem Cell Niches / Clara Alfaro-Cervello, Chiara Cossetti, Elena Giusto, Matteo Donegà and Stefano Pluchino -- 3. Cultured Limbal Epithelial Stem Cell Therapy for Ocular Surface Diseases / Hannah J. Levis, Julie T. Daniels and Sajjad Ahmad -- 4. Keratinocyte Stem Cells: Biology and Clinical Applications / Carlo Pincelli and Alessandra Marconi -- 5. Cardiac Regeneration with Stem Cells / Beatriz Pelacho, Manuel Mazo, Sheyla Montori, Ana Maria Simon-Yarza, Juan Jose Gavira, Maria J. Blanco-Prieto and Felipe Prósper -- 6. Development of Biological Approaches to Improve Muscle Healing After Injury and Disease / Jonathan D. Proto and Johnny Huard -- 7 Mesenchymal Stem Cells in Bone and Cartilage Regeneration / Mohamadreza Baghaban Eslaminejad, Elham Zomorodian and Fatemeh Bagheri -- 8. Pancreatic Reprogramming / Juan Domínguez-Bendala -- 9. Pancreatic Regeneration in the Face of Diabetes / Zeeshan Ahmad -- 10. Regenerative Therapies for Liver Diseases / Amar Deep Sharma, Ina Rittelmeyer, Tobias Cantz and Michael Ott -- 11. Clinical Studies of Cell Therapy for Liver Cirrhosis / James A. Thomas and Stuart J. Forbes -- 12. Stem Cell Applications for the Treatment of Gastrointestinal System Diseases / Jacobo Trebol Lopez, Tihomir Georgiev-Hristov, Mariano García-Arranz and Damián García-Olmo -- 13. Germ Line Stem Cells: A Promising Alternative Source for Stem-Cell-Based Therapies in Regenerative Medicine / Ellen Goossens and Herman Tournaye -- 14. Cord Blood Stem Cells and Regenerative Medicine / David T. Harris.
  • 2012
    George Church & Ed Regis.
    Status: Not Checked OutLane Catalog Record
    From bioplastics to H. sapiens 2.0 -- -3,800 Myr, Late Hadean : at the inorganic/organic interface -- -3,500 Myr, Archean : reading the most ancient texts and the future of living software -- -500 Myr, Cambrian : the mirror world and the explosion of diversity ; How fast can evolution go and how diverse can it be? -- -360 Myr, Carboniferous : "the best substitute for petroleum is petroleum" -- -60 Myr, Paleocene : emergence of mammalian immune system ; Solving the health care crisis through genome engineering -- -30,000 Yr, Pleistocene Park : engineering extinct genomes -- -10,000 Yr, Neolithic : industrial revolutions ; The agricultural revolution and synthetic genomics ; The BioFab Manifesto -- -100 Yr, Anthropocene : the third industrial revolution ; iGEM -- -1 Yr, Holocene : from personal genomes to immortal human components -- Epigenetic epilogue. +1 Yr, the end of the beginning, transhumanism, and the Panspermia Era : societal risks and countermeasures.
  • 2011 CRCnetBASE
    editors, R.K. Gaur, Yedidya Gafni, P. Sharma, V.K. Gupta.
    "RNA interference (RNAi) is a system within living cells that helps to control active genes and their activity level. Two types of small RNA molecules--microRNA (miRNA) and small interfering RNA (siRNA)--are central to RNA interference. The discovery of RNAi was preceded first by observations of transcriptional inhibition by antisense RNA expressed in transgenic plants and more directly by reports of unexpected outcomes in experiments performed by plant scientists in the U.S. and The Netherlands in the early 1990s. RNAi technology are used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. This book reviews the selective and robust effect of RNAi on gene expression which makes it a valuable research tool, both in cell culture and in living organisms because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. This book will introduce new technology in the study of RNA interference in microorganisms, plants and animals."--Provided by publisher.
  • 2002 NAP
    Committee on Science, Engineering, and Public Policy, Policy and Global Affairs Division, National Academy of Sciences, National Academy of Engineering, Institute of Medicine.
  • 2005 Springer
    edited by Trygve Gjedrem.
  • 2015 Springer
    Changming Sun, Tomasz Bednarz, Tuan D. Pham, Pascal Vallotton, Dadong Wang, editors.
    Signal and image analysis techniques are becoming more widely used in biomedical and life science applications. With an emphasis on applications of computational models for solving modern challenging problems in biomedical and life sciences, this book aims to bring collections of articles from biologists, medical/biomedical and health science researchers together with computational scientists to focus on problems at the frontier of biomedical and life sciences. The goals of this book are to build interactions of scientists across several disciplines and to help industrial users apply advanced computational techniques for solving practical biomedical and life science problems. This book is for users in the fields of biomedical and life sciences who wish to keep abreast with the latest techniques in signal and image analysis. The book presents a detailed description to some of the applications. It can be used by those both at graduate and specialist levels.
    Also available: Print – 2015
  • 2012 Springer Protocols
    edited by Debra J. Taxman.
    What parameters to consider and which software tools to use for target selection and molecular design of small interfering RNAs / Olga Matveeva -- Methods for selecting effective siRNA target sequences using a variety of statistical and analytical techniques / Shigeru Takasaki -- Designing functional siRNA with reduced off-target effects / Yuki Naito and Kumiko Ui-Tei -- Design and screening of siRNAs against highly structured RNA targets / Neda Nasheri, John Paul Pezacki, and Selena M. Sagan -- Engineering small interfering RNAs by strategic chemical modification / Jesper B. Bramsen and Jørgen Kjems -- Design, selection, and evaluation of highly specific and functional siRNA incorporating unlocked nucleobase analogs / Narendra Vaish and Pinky Agarwal -- Design, preparation and evaluation of asymmetric small interfering RNA for specific gene silencing in mammalian cells / Chanil Chang [and others] -- Design of nuclease-resistant fork-like small interfering RNA (fsiRNA) / Elena L. Chernolovskaya and Marina A. Zenkova -- Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and MicroRNA-like targeting / Pal Sætrom -- Strategies for designing and Validating immunostimulatory siRNAs / Michael P. Gantier -- Designing efficient and specific endoribonuclease-prepared siRNAs / Vineeth Surendranath [and others] -- Short hairpin RNA-mediated gene silencing / Luke S. Lambeth and Craig A. Smith -- Design of lentivirally expressed siRNAs / Ying Poi Liu and Ben Berkhout -- Bifunctional short hairpin RNA (bi-shRNA) : design and pathway to clinical application / Donald D. Rao [and others] -- Design and chemical modification of synthetic short shRNAs as potent RNAi triggers / Anne Dallas and Brian H. Johnston -- Production and application of long dsRNA in mammalian cells / Katerina Chalupnikova, Jana Nejepinska, and Petr Svoboda -- Design of RNAi reagents for invertebrate model organisms and human disease vectors / Thomas Horn and Michael Boutros -- Construction of shRNA expression plasmids for silkworm cell lines using single-stranded DNA and Bst DNA polymerase / Hiromitsu Tanaka -- Designing effective amiRNA and multimeric amiRNA against plant viruses / Muhammad Fahim and Philip J. Larkin -- Downregulation of plant genes with miRNA-induced gene silencing / Felipe Fenselau de Felippes.
  • 2008 CRCnetBASE
    edited by Igor Galaev, Bo Mattiasson.
  • 2002 CRCnetBASE
    edited by Igor Galaev and Bo Mattiasson.
  • 2008 Springer
    Yanhong Shi, Dennis O. Clegg, editors.
  • 2011 Springer
    Krishnarao Appasani, Raghu K. Appasani, editors ; foreword by Sir John B. Gordon.
    pt. 1. Stem cell biology -- pt. 2. Epigenetic and microRNA regulation in stem cells -- pt. 3. Stem cells for therapeutic applications -- pt. 4. Nuclear reprogramming and induced pluripotent stem cells -- pt. 5. Tissue engineering -- pt. 6. Regenerative medicine.
  • 2012 CRCnetBASE
    edited by Hyunjoon Kong, Andrew J. Putnam, Lawrence B. Schook.
    pt. 1. Defining, isolating, and characterizing various stem and progenitor cell populations for neovascularization -- pt. 2. In vitro studies for angiogenesis, vasculogenesis, and arteriogenesis -- pt. 3. Stem cell mobilization strategies -- pt. 4. Stem cell transplantation strategies.
  • 2014 Springer
    Melvin A. Shiffman, Alberto Di Giuseppe, Franco Bassetto, editors.
    Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed, and the wide range of aesthetic procedures involving stem cell fat transfer are then described in detail. These procedures relate to the face, breast, buttocks, legs, hands, penis, and Poland syndrome. In addition, potential risks and complications are identified. Stem Cells in Aesthetic Procedures: Art, Science, and Clinical Techniques is completely up to date and has been written by leading experts in the field. It will be an invaluable source of information for students, beginners, and experienced surgeons in the fields of plastic surgery, general surgery, cosmetic surgery, facial plastic surgery, otolaryngology, ophthalmology, and oral maxillofacial surgery.
  • 2009 Springer Protocols
    edited by Julie Audet and William L. Stanford.
    Derivation and manipulation of murine embryonic stem cells / Alexander Meissner, Sarah Eminli, and Rudolf Jaenisch -- Patterning mouse and human embryonic stem cells using micro-contact printing / Raheem Peerani ... [et al.] -- Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi / Asmin Tulpule and George Q. Daley -- Measurement of cell-penetrating peptide-mediated transduction of adult hematopoietic stem cells / Aziza P. Manceur and Julie Audet -- Stem cell sources for regenerative medicine / Ali M. Riazi, Sarah Y. Kwon, and William L. Stanford -- Investigating the interactions between haemopoietic stem cells and their niche : methods for the analysis of stem cell homing and distribution within the marrow following transplantation / Brenda Williams and Susan K. Nilsson -- Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells / Valérie Cortin, Nicolas Pineault, and Alain Garnier -- Ex vivo generation of human red blood cells : a new advance in stem cell engineering / Luc Douay and Marie-Catherine Giarratana -- Isolation and manipulation of mammalian neural stem cells in vitro / Claudio Giachino, Onur Basak, and Verdon Taylor -- Isolation, expansion, and differentiation of mouse skin-derived precursors / Karl J.L. Fernandes and Freda D. Miller -- Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord / Hynek Wichterle, Mirza Peljto, and Stephane Nedelec -- Transplantation of neural stem/progenitor cells into developing and adult CNS / Tong Zheng ... [et al.] -- Transplantation of embrynic stem cell-derived dopaminergic neurons in MPTP-treated monkeys / Jun Takahashi, Yasushi Takagi, and Hidemoto Saiki -- Isolation and culture of epithelial stem cells / Jonathan A. Nowak and Elaine Fuchs -- Regeneration of skin and cornea by tissue engineering / Danielle Larouche ... [et al.] -- Prospective isolation of mesenchymal stem cells from mouse compact bone / Brenton J. Short, Nathalie Brouard, and Paul J. Simmons -- Isolation, propagation, and characterization of human umbilical cord perivascular cells (HUCPVCs) / Rahul Sarugaser ... [et al.] -- Bone marrow-derived mesenchymal stem cells : isolation, expansion, characterization, viral transduction, and production of conditioned medium / Massimilano Gnecchi and Luis G. Melo -- Template DNA-strand co-segregation and asymmetric cell division in skeletal muscle stem cells / Vasily Shinin, Barbara Gayraud-Morel, and Shahragim Tajbakhsh -- Isolation and grafting of single muscle fibres / Charlotte A. Collins and Peter S. Zammit -- Differentiation and dynamic analysis of primitive vessels from embryonic stem cells / Gefei Zeng and Victoria L. Bautch -- Derivation of contractile smooth muscle cells from embryonic stem cells / Sanjay Sinha, Mark H. Hoofnagle, and Gary K. Owens -- Islet-derived progenitors as a source of in vitro islet regeneration / Stephen Hanley and Lawrence Rosenberg -- Isolation and characterization of hepatic stem cells, or "oval cells," from rat livers / Thomas D. Shupe ... [et al.] -- Reprogramming of liver to pancreas / Shifaan Thowfeequ ... [et al.]
  • 2009 Atypon
    Binseng Wang.
    Technology is essential to the delivery of health care but it is still only a tool that needs to be deployed wisely to ensure beneficial outcomes at reasonable costs. Among various categories of health technology, medical equipment has the unique distinction of requiring both high initial investments and costly maintenance during its entire useful life. This characteristic does not, however, imply that medical equipment is more costly than other categories, provided that it is managed properly. The foundation of a sound technology management process is the planning and acquisition of equipment, collectively called technology incorporation. This lecture presents a rational, strategic process for technology incorporation based on experience, some successful and many unsuccessful, accumulated in industrialized and developing countries over the last three decades. The planning step is focused on establishing a Technology Incorporation Plan (TIP) using data collected from an audit of existing technology, evaluating needs, impacts, costs, and benefits, and consolidating the information collected for decision making. The acquisition step implements TIP by selecting equipment based on technical, regulatory, financial, and supplier considerations, and procuring it using one of the multiple forms of purchasing or agreements with suppliers. This incorporation process is generic enough to be used, with suitable adaptations, for a wide variety of health organizations with different sizes and acuity levels, ranging from health clinics to community hospitals to major teaching hospitals and even to entire health systems. Such a broadly applicable process is possible because it is based on a conceptual framework composed of in-depth analysis of the basic principles that govern each stage of technology lifecycle. Using this incorporation process, successful TIPs have been created and implemented, thereby contributing to the improvement of healthcare services and limiting the associated expenses.
  • 2015 Knovel
    edited by Marcos Luciano Bruschi.
  • 2013 Springer Protocols
    edited by Karen M. Polizzi, Cleo Kontoravdi.
    In Synthetic Biology , expert researchers in the field provide the latest developments in molecular biology techniques used in Synthetic Biology. Focusing on computational tools that will aid in systematising the design and construction of parts and systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Synthetic Biology seeks to aid scientists in the further study of developing new biological components and systems.

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A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.

Over 10,000 notes outline the status of specific infections within each country.

Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.

Provides online, full-text access to Springer's journal titles as well as journals from other publishers.

Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.

Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.
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