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- 13th International Conference on Electrical Bioimpedance and the 8th Conference on Electrical Impedance Tomography ICEBI 2007, August 29th-September 2nd 2007, Graz, Austria — Functional foods and biotechnology (100)
- Fundamentals of pharmaceutical nanoscience — Practical guide to assay development and high-throughput screening in drug discovery (100)
- Principles of cloning. Second edition. [2nd ed.] — Women in biotechnology creating interfaces (51)
- Fundamentals of pharmaceutical nanoscience 2013SpringerNanoscience and nanotechnology overview -- Liposome preparation and characterization -- Solid polymeric nanoparticles -- Lipid nanoparticles -- Polymeric vesicles -- Low molecular weight amphiphile micelles -- Polymeric micelles -- Niosomes -- Quantum dots -- Magnetic particles -- Drug nanoparticles -- Polymeric pro-drugs -- Therapeutic Applications of pharmaceutical nanosystems -- Drug solubilisation -- Gene therapy -- Chemotherapy -- Tissue engineering -- Anti-infectives -- Vaccination -- Anti-arthritic drugs -- Imaging agents -- Commercial exploitation of pharmaceutical nanosystems -- Future perspectives -- Multiple Choice -- Problem Sets -- Case Studies -- Suggested Reading.
- Gene biotechnology. Third Edition [3rd ed.]. 2011CRCnetBASE"The third edition of this popular reference covers a variety of techniques related to gene manipulation, including DNA isolation, preparation, screening, and analysis. Topics range from very basic methods to current and sophisticated technologies, including methodologies created and tested by the authors. Other topics include approaches to grant funding and SiRNA technology. The authors offer detailed, step-by-step explanations of protocols and helpful troubleshooting guides. This edition features new techniques for every chapter, as well as several new chapters"--Provided by publisher.
- Part 1. Application and Perspectives -- ch. 1. Transgenic Modification of Production Traits in Farm Animals / Mathias Müller and Gottfried Brem -- ch. 2. Genetically Modified Plants / Susanne Stirn and Horst Lörz -- ch. 3. Fermented Food Production using Genetically Modified Yeast and Filamentous Fungi / Anke Niederhaus and Ulf Stahl -- ch. 4. Production of Food Additives using Filamentous Fungi / Carsten M. Hjort -- ch. 5. Perspectives of Genetic Engineering of Bacteria used in Food Fermentations / Arnold Geis -- Part II. Legislation in Europe -- ch. 6. The Legal Situation for Genetically Engineered Food in Europe / Rudolf Streinz and Lars O. Fuchs -- Part III. Methods of Detection -- ch. 7. Detection of Genetic Modifications: Some Basic Considerations / Knut J. Heller -- ch. 8. DNA-based Methods for Detection of Genetic Modifications / Ralf Einspanier and Stephanie Rief -- ch. 9. Genetic Engineering of Fishes and Methods for Detection / Hartmut Rehbein -- ch. 10. Detection Methods for Genetically Modified Crops / Rolf Meyer -- ch. 11. Methods to Detect the Application of Genetic Engineering in Composed and Processed Foods / Karl-Heinz Engel and Francisco Moreano -- ch. 12. Mutations in Lactococcus lactis, and their Detection / Jan Kok and Bertus van den Burg -- ch. 13. Detection Methods for Genetically Modified Microorganisms used in Food Fermentation / Walter P. Hammes, Christian Hertel and Torsten Bauer.
- Part I. Application and Perspectives -- ch. 1. Transgenic modification of production traits in farm animals / Gottfried Brem, Mathias Müller -- ch. 2. Genetically modified plants / Susanne Stirn, Horst Lörz -- ch. 3. Fermentation of food by means of genetically modified yeast and filamentous fungi / Rena Leisegang, Elke Nevoigt, Anja Spielvogel, Georg Kristan, Anke Niederhaus, Ulf Stahl -- ch. 4. Production of food additives using filamentous fungi / Carsten M. Hjort -- ch. 5. Genetic engineering of bacteria used in food fermentation / Arnold Geis -- Part II. Legislation in Europe -- ch. 6. The Legal situation for genetically engineered food in Europe / Rudolf Streinz, Jan Kalbheim -- Part III. Methods of Detection -- ch. 7. Detection of genetic modifications : some basic considerations / Knut J. Heller -- ch. 8. DNA-based methods for detection of genetic modifications / Ralf Einspanier -- ch. 9. Genetic engineering of fish, and methods of detection / Hartmut Rehbein -- ch. 10. Detection methods for genetically modified crops / Rolf Meyer -- ch. 11. Methods for detection of genetically modified organisms in composite and processed foods / Karl-Heinz Engel, Francisco Moreano, Alexandra Ehlert -- ch. 12. Mutations in Lactococcus lactis and their detection / Jan Kok, Bertus van den Burg -- ch. 13. Methods for detection of genetically modified microorganisms used in food fermentation processes / Walter P. Hammes, Christian Hertel, Torsten Bauer.
- Genomes. 2nd ed. 2002NCBI Bookshelf
- The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) is a unique project that brings together the regulatory authorities of Europe, Japan and the US and experts from the pharmaceutical industry in the three regions to discuss scientific and technical aspects of product registration. In Japan, the members are the Ministry of Health, Labour and Welfare (MHLW), and the Japan Pharmaceutical Manufacturers Association (JPMA). In Europe, the members are the EU (Representatives of the European Commission and the European Medicines Agency [EMA]), and the European Federation of Pharmaceutical Industries and Associations (EFPIA). In the United States, the members are the Food and Drug Administration (FDA), and the Pharmaceutical Research and Manufacturers of America (PhRMA). The International Federation of Pharmaceutical Manufacturers Associations (IFPMA) is the secretariat of the ICH. Additional members include Observers from WHO, European Free Trade Association (EFTA), and Canada. The Observers represent non-ICH countries and regions. This volume considers one of ICH's major categories, Safety, covering topics relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.). Since the start of the ICH process, many guidelines have been written, but in most cases there is a lack of awareness of the many issues that were addressed during the development of the consensus guidances. Further, just as it is important to understand what the guidances state, it is also important to understand the thoughts, debates, and intent of the experts involved, which are not included in the guidance documents. Why has the guideline been written as it is written, why are some topics ignored, and why have some initial guidance proposals have been deleted. These and other related questions and answers are the contents of this book, written by experts who were directly involved in writing the ICH guidances that drive drug development today.
- Glossary of biotechnology terms. 3rd ed. 2002CRCnetBASE
- Guide to protein purification. 2nd ed. 2009ScienceDirect
- ch. 1. Introduction -- ch. 2. Genetically modified foods -- ch. 3. DNA data banking -- ch. 4. Personalized medicine -- ch. 5. Stem Cells -- ch. 6. Conclusion.
- Handbook of carbohydrate engineering 2005CRCnetBASE
- Handbook of Corynebacterium glutamicum 2005CRCnetBASE
- Handbook of cryo-preparation methods for electron microscopy 2009CRCnetBASEVitreous water / Jacques Dubochet -- Slam-freezing, metal-mirror freezing / Danièle Spehner and Ludwig Edelmann -- Plunge-freezing (Holey carbon method) / Sacha De Carlo -- Controlled vitrification / Peter M. Frederik, Felix de Haas, and Marc M.H. Storms -- BAL-TEC HPM 010 high-pressure freezing machine / Andres Kaech -- High-pressure freezing LEICA EMPACT / Dimitri Vanhecke and Daniel Studer -- Frozen-hydrated macromolecules for structural analysis / Corinne Crucifix, Gabor Papai, and Patrick Schultz -- 2-D crystals / Patrick Bron and Janet Vonck -- Cryo-negative staining / Sacha De Carlo -- Vitrification of dynamic microtubules / Isabelle Arnal, Marine Malleter, and Denis Chrétien -- CEMOVIS : cryo-electron microscopy of vitreous sections / Jacques Dubochet ... [et al.] -- Cryo-electron tomography / Andrew Leis, Manuela Gruska, and Wolfgang Baumeister -- Freeze-substitution / Bruno M. Humbel -- Cryo-fixation, freeze-substitution, rehydration and Tokuyasu cryo-sectioning / York-Dieter Stierhof ... [et al.] -- Freeze-drying and embedding of biological material / Ludwig Edelmann -- The shadow of hydrated biological specimens / Daniel Thomas -- Cryo-fracture of self assembled systems in organic solvent / Marc Schmutz and Philippe J. Mésini -- Progressive lowering of temperature for immunolabeling and in situ hybridization / Annie Cavalier and Danièle Spehner -- Cryo-sectioning according to Tokuyasu / Bruno M. Humbel and York-Dieter Stierhof -- Cryo-preparation procedures for elemental imaging by SIMS and EFTEM / Christian Bordat and Jean-luc Guerquin-Kern -- Correlative light and electron microscopy / Heinz Schwarz and Bruno M. Humbel -- SDS-digested freeze-fracture replica labeling (SDS-FRL) / Yugo Fukazawa ... [et al.] -- Immunolabeling of ultra-thin sections with enlarged 1 nm gold or QDots / York-Dieter Stierhof -- 3-D electron tomography of cells and organelles / Willie J.C. Geerts, Bruno M. Humbel and Arie J. Verkleij -- Final considerations / Hellmuth Sitte.
- Handbook of food and bioprocess modeling techniques 2007CRCnetBASEMathematical modeling techniques in food and bioprocessing: an overview / Ashim K. Datta and Shyam S. Sablani -- Lattice Boltzmann modeling / R.G.M. van der Sman -- Fluid flow and computational fluid dynamics / Ashwini Kumar and Ilhan Dilber -- Heat transfer / Ashim K. Datta -- Mass transfer: membrane processes / David Hughes, Taha Taha, and Zhanfeng Cui -- Heat and mass transfer / X. Dong Chen -- Reaction kinetics / Maria C. Giannakourou and Petros S. Taoukis -- Probabilistic modeling / Bart M. Nicolai, Nico Scheerlinck, and Maarten Hertog -- Experimental design and response surface methodology / Shuryo Nakai, Eunice C.Y. Li-Chan, and Jinglie Dou -- Multivariate analysis / Ioannis S. Arvanitoyannis -- Data mining / Geoffrey Holmes -- Artificial neural network modeling / Shyam S. Sablani -- Genetic algorithm / T. Morimoto -- Fractal analysis / M. Shafiur Rahman -- Fuzzy modeling / Haitham M. S. Lababidi and Christopher G. J. Baker -- Monte-Carlo simulation / Kevin Cronin & James P. Gleeson -- Dimensional analysis / Law C. Lim, Shyam S. Sablani, and Arun S. Mujumdar -- Linear programming / Eli Feinerman and Sam Saguy.
- Handbook of industrial mycology 2005CRCnetBASE
- Handbook of membrane separations chemical, pharmaceutical, food, and biotechnological applications 2009CRCnetBASE
- High pressure bioscience 2015SpringerPart I. Why and how proteins denature under prssure? -- Part II. Volume, compressibility, fluctuation and interaction in proteins -- Part III. Pressure and functional sub-states in proteins -- Part IV. Pressure and protein folding and assembly -- Part V. Pressure effects on biological membranes -- Part VI. Pressure adaptation and tolerance of proteins and living organisms -- Part VII. High pressure food processing and sterilization -- Part VIII. Pressure effects on motility, physiology and health -- Part IX. Methodology.
- Human ATP-binding cassette (ABC) transporter superfamily 2002NCBI BookshelfIntroduction to ABC protein and gene organization -- Nomenclature -- Overview of human ABC gene subfamilies -- ABC genes and human genetic disease -- Mouse knockouts -- Multidrug resistance and cancer therapy -- Phylogenetic analysis of human ABC genes -- Mouse ABC genes -- Drosophila ABC genes -- ABCA genes -- ABCB genes -- ABCC genes -- ABCD genes -- ABCE genes -- ABCF genes -- ABCG genes.
- Immobilization of enzymes and cells. 2nd ed. 2006Springer Protocols
- The collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modulation of foreign body reactions is therefore essential for preserving anticipated functions and avoiding adverse effects. Topics covered include mechanistic and applied research within the fields of extracorporeal devices, soft and hard tissue implants, tissue and biomaterial-targeting, therapeutic modulation of foreign body reactions, cell encapsulations, as well as cell and whole organ transplantation.
- Immunological barriers to regenerative medicine 2013SpringerRecent years have witnessed numerous advances in stem cell research that have suggested novel strategies for the treatment of the chronic and regenerative diseases that pose a growing challenge to the provision of healthcare in the 21<sup>st</sup> century. Nevertheless, there is little doubt that related disciplines have failed to keep pace with such developments, of which the immunology of transplant rejection is perhaps the most relevant to the nascent field of regenerative medicine. Indeed, given that after decades of research into the mechanisms of organ allograft rejection, we remain wholly dependent on immune suppression to ensure acceptance of foreign tissues, we might legitimately ask whether there is any reason why tissues differentiated from stem cells might not suffer the same fate. This volume seeks to address this issue by drawing on the principles of alloantigen recognition to assess the validity of early convictions that embryonic stem cell-derived tissues may prove invisible to the immune system of the host and the more recent belief that induced pluripotent stem cells, derived in a fully autologous manner, will circumvent the issue of immunogenicity. Having debunked such assumptions and established the magnitude of the immunological barriers to be overcome, this book then draws on the expertise of internationally-recognised laboratories around the world to provide a critical assessment of the likely success of applying strategies such as stem cell banking, silencing of genes that confer immunogenicity, and the induction of transplantation tolerance to overcoming the immunological barriers in the future. Indeed, it is only through reaching a consensus in the field that enduring solutions to such an intractable problem may ultimately emerge.
- Implantable cardiac devices technology 2013SpringerHistory and development of pacing -- Basic principles of cardiac pacemaker technology -- Heart anatomy and physiology -- Pharmacological treatment of cardiac rhythm disorders -- Pacing modes -- Indications for implantable system treatment -- Leads -- Pacing systems -- Pacemaker timing -- Implantable cardioverter-defibrillators -- Cardiac resynchronization therapy -- Implantation, explantation, and replacement of devices and leads -- Patient follow-up -- Electromagnetic compatibility and technical requirements.
- Induced pluripotent stem cells 2012Springer
- Industrial pharmaceutical biotechnology 2002Wileych. 1. Introduction to Functional Biotechnology, p. 1-72 -- ch. 2. Organizational Structures, p. 73-76 -- ch. 3. Markets and Factors, p. 77-78 -- ch. 4. Biotechnology and Medicine, p. 79-116 -- ch. 5. Drug Discovery, p. 117-144 -- ch. 6. Molecular Pharma-Biotechnology, p. 145-194 -- ch. 7. Research and Development, p. 195-200 -- ch. 8. Pharmaceutical Production, p. 201-238 -- ch. 9. Safety, p. 239-240 -- ch. 10. Environment, p. 241-243 -- ch. 11. Ethics, p. 245-246 -- ch. 12. Companies, Institutes, Networks, and Organizations, p. 247-261.
- Industrial proteins in perspective 2003ScienceDirect
- Print MaterialThis book covers both basic elements and the state-of-the-art in applications of proteomics. The first section gives an introduction to the field, from differential approaches to functional proteomics, including yeast two-hybrid, mass spectrometry, mapping of post-translational modifications, and NMR spectroscopy. The second section offers a complete picture of industry studies in proteomics for human health and biotechnology applications. The final section addresses the future, looking at the most promising areas such as protein arrays and the integration of genomic and proteomic tools.
- Integrated microfabricated biodevices advanced technology for genomics, drug discovery, bioanalysis, and clinical diagnostics 2002CRCnetBASE
- Intellectual property and health technologies balancing innovation and the public's health 2014SpringerIntroduction to intellectual property -- Obtaining, enforcing and defending patents -- The patent-eligibility of genes -- Medical procedure patents -- Rights and roles of universities and inventors -- Drug development : balancing innovation, access and profits -- Patent battles part I : small-molecule drugs -- Patent battles part II : the Biosimilars Act and biologics -- International patent law, trade law, and access to drugs.
- Introduction to biophotonics 2003Wileych. 1. Introduction -- ch. 2. Fundamentals of Light and Matter -- ch. 3. Basics of Biology -- ch. 4. Fundamentals of Light-Matter Interactions -- ch. 5. Principles of Lasers, Current Laser Technology, and Nonlinear -- ch. 6. Photobiology -- ch. 7. Bioimaging: Principles and Techniques -- ch. 8. Bioimaging: Applications -- ch. 9. Biosensors -- ch. 10. Microarray Technology for Genomics and Proteomics -- ch. 11. Flow Cytometry -- ch. 12. Light-Activated Therapy: Photodynamic Therapy -- ch. 13. Tissue Engineering with Light -- ch. 14. Laser Tweezers and Laser Scissors -- ch. 15. Nanotechnology for Biophotonics: Bionanophotonics -- ch. 16. Biomaterials for Photonics.
- Introduction to fluorescence sensing 2009Springer
- Isolation and purification of proteins 2003CRCnetBASE
- This book discusses the full range of current applications of computer-assisted surgery and robotics in the field of knee surgery, and also considers potential future applications. The impact of computer-assisted surgery on a wide range of surgical procedures is clearly explained. Procedures considered include total knee arthroplasty, unicompartmental knee arthroplasty, cruciate ligament reconstruction, patellofemoral arthroplasty, and revision surgery. In each case, technical aspects are thoroughly addressed in a readily understandable manner. Knee Surgery Using Computer-Assisted Surgery and Robotics will be an ideal guide to this exciting field for both novice and more experienced surgeons who treat knee injuries and disorders.
- Laboratory methods in enzymology DNA. First edition [1st ed.] 2013ScienceDirectExplanatory chapter: PCR primer design / Rubén Álvarez-Fernández -- How plasmid preparation kits work / Laura Koontz -- Introducing exogenous DNA into cells / Laura Koontz -- Agarose gel electrophoresis / Laura Koontz -- Analysis of DNA by southern blotting / Gary Glenn and Lefkothea-Vasiliki Andreou -- Purification of DNA oligos by denaturing polyacrylamide gel electrophoresis (PAGE) / Sara Lopez-Gomollon and Francisco Esteban Nicolas -- Molecular cloning / Juliane C. Lessard -- Rapid creation of stable mammalian cell lines for regulated expression of proteins using the Gateway® recombination cloning technology and Flp-In T-REx® lines / Jessica Spitzer, Markus Landthaler, and Thomas Tuschl -- Restrictionless cloning / Mikkel A. Algire -- Isolation of plasmid DNA from bacteria / Lefkothea-Vasiliki Andreou -- Preparation of genomic DNA from bacteria / Lefkothea-Vasiliki Andreou -- Preparation of genomic DNA from Saccharomyces cerevisiae / Jessica S. Dymond -- Isolation of genomic DNA from mammalian cells / Cheryl M. Koh -- Sanger dideoxy sequencing of DNA / Sarah E. Walker and Jon Lorsch -- Preparation of fragment libraries for next-generation sequencing on the applied biosystems SOLiD platform / Srinivasan Yegnasubramanian -- Next generation sequencing / Srinivasan Yegnasubramanian -- Generating mammalian stable cell lines by electroporation / Patti A. Longo, Jennifer M. Kavran, Min-Sung Kim, and Daniel J. Leahy -- Transient mammalian cell transfection with polyethylenimine (PEI) / Patti A. Longo, Jennifer M. Kavran, Min-Sung Kim, and Daniel J. Leahy -- Site-directed mutagenesis / Julia Bachman -- PCR-based random mutagenesis / Jessica S. Dymond -- Megaprimer method for mutagenesis of DNA / Craig W. Vander Kooi -- Troubleshooting PCR / Kirstie Canene-Adams -- Quantitative PCR / Jessica S. Dymond -- General PCR / Kirstie Canene-Adams -- Colony PCR / Megan Bergkessel and Christine Guthrie -- Chemical transformation of yeast / Megan Bergkessel and Christine Guthrie -- Transformation of E. coli via electroporation / Juliane C. Lessard -- Transformation of chemically competent E. coli / Rachel Green and Elizabeth J. Rogers.
- Laboratory methods in enzymology RNA. First edition [1st ed.] 2013ScienceDirectComputational prediction of RNA secondary structure -- Reverse-transcription PCR (RT-PCR) -- Northern blotting -- Explanatory chapter: nuclease protection assays -- In vitro transcription from plasmid or PCR-amplified DNA -- Measurement of in vivo synthesis rates -- Method for measuring mRNA decay rate in saccharomyces cerevisiae -- Analysis of polysomes from bacteria -- Polysome profile analysis - yeast -- Polysome analysis of mammalian cells -- Polysome analysis for determining mRNA and ribosome association in saccharomyces cerevisiae -- Oligo(dT)-primed RT-PCR isolation of polyadenylated RNA degradation intermediates -- Circularized RT-PCR (cRT-PCR): analysis of the 5' ends, 3' ends, and poly(A) tails of RNA -- RNA radiolabeling -- Fluorescently labeling synthetic RNAs -- Analysis of RNA by analytical polyacrylamide gel -- RNA purification by preparative polyacrylamide gel -- Explanatory chapter: nucleic acid concentration determination -- RNA purification-precipitation methods -- Reverse transcriptase dideoxy sequencing of RNA -- RNA structure experimental analysis-chemical modification -- Structural analysis of RNA backbone using in-line probing.
- Lateral flow immunoassay 2009Springer
- Lateral gene transfer in evolution 2013Springer"Although the phenomenon of lateral gene transfer has been known since the 1940s, it was the genomics era that has really revealed the extent and many facets of this evolutionary/genetic phenomenon. Even in the early 2000s with but a handful of genomes available, it became clear that the nature of microorganisms is full of genetic exchange between lineages that are sometimes far apart. The years following this saw an explosion of genomic data, which shook the "tree of life" and also raised doubts about the most appropriate species concepts for prokaryotes. This book represents the manyfold contributions of LGT to the evolution of micro and, to an extent, macroorganisms by focusing on the areas where it has the largest impact: metabolic innovations and adaptations and speciation." Back cover.
- Lentivirus gene engineering protocols 2003Springer Protocols
- Lipid biotechnology 2002CRCnetBASEPart I. Oilseed Quality Improvement -- 1. Metabolic Engineering of Fatty Acid Biosynthesis / David J. Schultz and John B. Ohlrogge -- 2. Biochemistry and Biotechnology of Triacylglycerol Accumulation in Plants / Randall J. Weselake -- 3. Redirecting Lipid Metabolism in Plants / David Hildebrand, Suryadevara Rao, and Tomoko Hatanaka -- 4. Perspectives on the Production of Industrial Oils in Genetically Engineered Oilseeds / Anthony J. Kinney -- 5. New Gene Combinations Governing Saturated and Unsaturated Fatty Acid Composition in Soybean / Richard F. Wilson, Joseph W. Burton, Vincent R. Pantalone, and Ralph E. Dewey -- 6. Strategies for the Development of NuSun Sunflower Hybrids / Brady A. Vick and Jerry F. Miller -- 7. Biosynthesis of Ricinoleic Acid for Castor-Oil Production / Thomas A. McKeon and Jiann-Tsyh Lin -- Part II. Oxylipins: Formation, Potential Uses, and Their Role in Defense -- 8. Enzymatic Transformation of Lipids as a Plant Defense Mechanism / Daisuke Shibata and Hiroyuki Ohta -- 9. Biocatalysis by the Plant Lipoxygenase Pathway: Oxygenated Fatty Acid Production and Hydroperoxide Lyases / Harold W. Gardner and Alexander N. Grechkin -- 10. Biocatalysis by the Plant Lipoxygenase Pathway: Hydroperoxide-Metabolizing Enzymes / Alexander N. Grechkin and Harold W. Gardner -- 11. Prostaglandin-like Oxylipins in Plants: Biosynthesis, Molecular Signaling, and Response to Environment / Martin J. Mueller -- 12. Cutin Monomers: Biosynthesis and Plant Defense / Elizabeth Ble -- 13. Structural Diversity of Marine Oxylipins -- William H. Gerwick and Inder Pal Singh -- 14. Formation of Oxygenated Fatty Acids by Fungal Enzymes / Ernst Oliw and Chao Su -- 15. Enzymic Formation of Flavor Volatiles from Lipids / Wilfried Schwab and Peter Schreier -- 16. Terpenoid-Based Defense in Plants and Other Organisms / Mario R. Tellez, Stephen O. Duke, Kevin K. Schrader, Franck E. Dayan, Joanne G. Romagni, and Mozaina Kobaisy -- Part III. Lipases and Food Nutrition -- 17. Lipases: Structure, Function, and Properties / Alejandro G. Marangoni -- 18. Industrial Uses of Lipase / Ching T. Hou -- 19. Plant Lipases as Biocatalysts / Kumar D. Mukherjee -- 20. Phospholipases in Enzyme Engineering of Phospholipids for Food, Cosmetics, and Medical Applications / Yugo Iwasaki and Tsuneo Yamane -- 21. Enzymatic Synthesis of Structured Lipids / Casimir C. Akoh, Subramani Sellappan, Lydia B. Fomuso, and Vivienne V. Yankah / 22. Enzymatic Production of Betapol and Other Specialty Fats / Casimir C. Akoh and Xuebing Xu -- 23. Enzyme-Mediated Modification of Milkfat / Victor M. Balcdo and F. Xavier Malcata -- 24. Enzymatic Enrichment of Polyunsaturated Fatty Acids / Yuji Shimada, Akio Sugihara, and Yoshio Tominaga -- 25. Production of Tailor-Made Polyunsaturated Phospholipids Through Bioconversions / Koretaro Takahashi and Masashi Hosokawa -- Part IV. Biocatalysts in Nonfood Applications -- 26. Enzymatic Preparation of Chiral Pharmaceutical Intermediates by Lipases / Ramesh N. Patel -- 27. Production of C20 Polyunsaturated Fatty Acids by an Arachidonic Acid-Producing Fungus Mortierella alpina 1S-4 and Related Strains / Jun Ogawa, Eiji Sakuradani, and Sakayu Shimizu -- 28. Microbial Transformations of Steroids / Herbert L. Holland -- 29. Enzymatic Approaches to the Production of Biodiesel Fuels / Michael J. Haas, George J. Piazza, and Thomas A. Foglia -- 30. Lipase-Catalyzed Synthesis of Value-Added Fatty Acid Esters / Jei-Fu Shaw -- 31. Microbiological Conversions of Fatty Acids to Value-Added Products / Tsung Min Kuo, Tsuneo Kaneshiro, and Ching T. Hou -- 32. Biosynthesis and Applications of Glycolipid and Lipopeptide Biosurfactants / David C. Herman and Raina M. Maier -- 33. Application of Lipolytic Enzymes in Detergents / Maarten R. Egmond -- 34. Supercritical Fluid Technology for Lipid Extraction, Fractionation, and Reactions / Jerry W. King -- 35. Enzyme Reactions in Supercritical Fluids / Osato Miyawaki and Kozo Nakamura.
- Luminescence biotechnology instruments and applications 2002CRCnetBASE
- "This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student, or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research"--Provided by publisher.
- Maximising the value of marine by-products 2007CRCnetBASEpt. 1. Marine by-products characterisation, recovery and processing: 1. Physical and chemical properties of protein seafood by-products / T. Rustad ; 2. Physical and chemical properties of lipid by-products from seafood waste / J.P. Kerry and S.C. Murphy ; 3. On-board handling of marine by-products to prevent microbial spoilage, enzymatic reactions and lipid oxidation / E. Falch, M. Sandbakk and M. Aursand ; 4. Recovery of by-products from seafood processing streams / J.A. Torres ... [et al.] ; 5. Increasing processed flesh yield by recovery from marine by-products / K.D.A. Taylor and A. Himonides ; 6. Enzymatic methods for marine by-products recovery / F. Guerard ; 7. Chemical processing methods for protein recovery from marine by-products and underutilized fish species / H.G. Kristinsson, A.E. Theodore and B. Ingadottir -- pt. 2. Food uses of marine by-products: 8. By-catch, underutilized species and underutilized fish parts as food ingredients / I. Batista ; 9. Mince from seafood processing by-product and surimi as food ingredients / J.-S. Kim and J.W. Park ; 10. Aquatic food protein hydrolysates / H.G. Kristinsson ; 11. Engineering and functional properties of powders from underutilized marine fish and seafood products / S. Sathivel and P.J. Bechtel ; 12. Marine oils from seafood waste / F. Shahidi ; 13. Collagen an gelatin from marine by-products / J.M. Regenstein and P. Zhou ; 14. Seafood flavor from processing by-products / C.M. Lee ; 15. Fish and bone as a calcium source / S.-K. Kim and W.-K. Jung ; 16. Chitin and chitosan from marine by-products / F. Shahidi ; 17. Marine enzymes from seafood by-products / M.T. Morrissey and T. Okada ; 18. Antioxidants from marine by-products / F. Shahidi and Y. Zhong ; 19. Pigments from by-products of seafood processing / B.K. Simpson -- pt. 3. Non-food uses of marine by-products: 20. By-products from seafood processing for aquaculture and animals feeds / P.J. Bechtel ; 21. Using marine by-products in pharmaceutical, medical and cosmetic products / J. Losso ; 22. Bio-diesel and bio-gas production from seafood processing by-products / R. Zhang and H.M. El-Mashad ; 23. Composting of seafood wastes / A.M. Martin.
- Mechanics of cellular bone remodeling coupled thermal, electrical, and mechanical field effects 2013CRCnetBASEIntroduction to bone materials -- Basic bone remodeling theory -- Multifield internal bone remodeling -- Multifield surface bone remodeling -- Theoretical models of bone modeling and remodeling -- Effect of parathyroid hormone on bone metabolism -- Cortical bone remodeling under mechanical stimulus -- Bone remodelling under pulsed electromagnetic fields and clinical applications -- Experiments.
- Medical biomethods handbook 2005Springer2005 Springer ProtocolsBasic techniques in molecular biology / Ralph Rapley -- Probe design, production, and applications / Marilena Aquino de Muro -- Restriction enzymes: tools in clinical research / Gareth J.S. Jenkins -- Southern blotting as a diagnostic method / Bronwen Harvey and Pirkko Soundy -- Western blotting as a diagnostic method / Pirkko Soundy and Bronwen Harvey -- Principles and medical applications of the polymerase chain reaction / Bimal D. M. Theophilus -- Single strand conformation polymorphism (SSCP) analysis / Igor Vorechovsky -- Denaturing gradient gel electrophoresis (DGGE) / Jeroen H. Roelfsema and Dorien J.M. Peters -- Quantitative analysis of DNA sequences by PCR and solid phase sequencing / Anu Suomalainen and Ann-Christine Syvänen -- Introduction to capillary electrophoresis of DNA: biomedical applications / Beatriz Sanchez-Vega -- Mapping techniques / Simon G. Gregory -- Dideoxyfingerprinting for mutation detection / Ioannis Bossis, Antonios Voutetakis, and Constantine A. Stratakis -- Conformation sensitive gel electrophoresis / Marian Hill -- Amplification refractory mutation system and molecular diagnostics / Richard Kitching and Arun Seth -- Ligase chain reaction / Carla Osiowy -- Chemical cleavage of mismatch: theory and clinical applications / Neil V. Whittock and Louise Izatt -- The protein truncation test / Johan T. den Dunnen -- Linkage, allele sharing, and association / Mara Giordano -- Single nucleotide polymorphisms: technology and applications / Cyril Mamotte, Frank Christiansen, and Lyle J. Palmer -- cDNA microarrays / Philip G. Febbo -- Nucleic acid sequence-based amplification / Katherine Loens, D. Ursi, H. Goosens, and M. Ieven -- The oligonucleotide ligation assay / Faye A. Eggerding -- Quantitative taqman real-time PCR: diagnostic and scientific applications / Jörg Dötsch, Ellen Schoof, and Wolfgang Rascher -- Use of denaturing high-performance liquid chromatography in molecular medicine / Elizabeth L. Rugg and Gareth J. Magee -- Quantitative PCR / David Sugden -- Liquid chromatography-mass spectrometry of nucleic acids / Herbert Oberacher and Walther Parson -- Comparative genomic hybridization in clinical and medical research / Peng-Hui Wang, Yann-Jang Chen, and Chi-Hung Lin -- Bioinformatics tools for gene and protein sequence analysis / Bernd H.A. Rehm and Frank Reinecke -- In situ hybridization / Amanda D. Watters -- Enzyme-linked immunosorbent assay / William J. Jordan -- Protein therapeutics: mouse, humanized, and human antibodies / Benny K.C. Lo -- Karyotyping / Avery A. Sandberg, John F. Stone, and Zhong Chen -- Microsatellite analysis / Rachel E. Ibbotson and Anton E. Parker -- Analysis of chromosomal translocations / Andreas Hochhaus -- Differential display: theory and applications / Irina Gromova, Pavel Gromov, and Julio E. Celis -- Techniques for gene expression profiling / Mark P. Richards -- Capillary electrophoresis in clinical analysis / Margaret A. Jenkins and Sujiva Ratnaike -- Flow cytometry in the biomedical arena / James L. Weaver and Maryalice Stetler-Stevenson -- Immunocytochemistry / Patricia A. Fetsch -- Ribotyping in clinical microbiology / Patricia Severino and Sylvain Brisse -- Diagnostic applications of protein microarrays / Samir Hanash -- The human genome project / Rahul Chodhari and Eddie Chung -- Prenatal diagnosis of inborn errors of metabolism / Guy T.N. Besley -- Gene therapy: methods and application / Stella B. Somiari.
- Medical enhancement and posthumanity 2008Springer
- 1. Mesenchymal stromal cells in regressive medicine: a perspective / Peiman Hematti and Armand Keating -- 2. MSCs: changing hypotheses, paradigms, and controversies on mechanisms of action in repairing tissues / Darwin J. Prockop and Roxanne L. Reger -- 3. MSCs: the need to rethink / Paolo Bianco and Pamela G. Robey -- 4. Characterization of MSCs: from early studies to the present / Mark F. Pittenger -- 5. MSCs as therapeutics / Arnold I. Caplan -- 6. MSC niche for hematopoiesis / Daniel Lucas, Sandra Pinhol and Paul S. Frenette -- 7. Immunomodulatory properties of MSCs / Maria Ester Bernardo, Lynne M. Ball, Franco Locatelli and Willem E. Fibbe -- 8. MSCs and inmate immune responses: a balancing act / Krisztián Németh and Éva Mezey -- 9. MSCs: paracrine effects / Siddiraju V. Boregowda and Donald G. Phinney -- 10. Cross-talk between MSCs and their environments / Thomas P. Lozito and Rocky S. Tuan -- 11. Human MSCs from bone marrow, umbilical cord blood, and adipose tissue: all the same? / Patrick Wuchter and Anthony D. Ho -- 12. MSCs in solid tumors and hematological malignancies: from basic biology to therapeutic applications / Rodrigo Jaeamo, Erika Spaeth, Venkata Battula, Frank Marini and Michael Andreeff -- 13. MSC studies in large-animal models / Bruce A. Bunnell, Christine Gagliardi, and Maria Isabel Ribeiro Dias -- 14. Defining the potential of MSCs with a prenatal large animal model / Grac̦a Almeida-Porada, Christopher D. Orada and Esmail D. Zanjani -- 15. Bench-to-bedside development of MSC therapies: a multidisciplinary approach / Sowmya Viswanathan and Elizabeth J. Read -- 16. cGMP production of MSCs / Derek J. Hei and David H. McKenna, Jr. -- 17. MSCs: the US regulatory perspective / Adrian P. Gee -- 18. MSCs: clinical applications and European regulatory aspects / Jens Reinhardt, Egbert Flory, Isabel Büttel, Christa Schröder, Stefan Fricke, Vladan Vucinic, Michael Cross and Dietger Niederwieser -- 19. Stem cell treatments around the World: boon or bane?/ Alok Srivastava -- 20. Safety issues in MSC therapy / Minoo Battiwalla and A. John Barrett -- 21. In vivo imaging of MSCs / Jeff W.M. Bulte -- 22. National Heart, Lung and Blood Institute support of cellular therapies regenerative medicine / Traci Heath Mondoro and John Thomas -- 23. MSC therapy of inborn errors / Edwin M. Horwitz -- 24. MSCs for enhancement of hematopoietic progenitor cell engraftment and poor graft function / Paolo F. Caimi and Hillard M. Lazarus -- 25. MSCs ro graft-versus-host disease / Jakub Tolar, Katarina Le Blanc and Bruce R. Blazar -- 26. MSCs in pediatric hematopoietic stem cell transplantation / Lynne M. Ball, Maria Ester Bernardo, Franco Locatelli and R. Maarten Egeler -- 27. MSC for ex vivo expansion of umbilical cord blood cells / Ian K. McNiece, Simon N. Robinson, and Elizabeth J. Shpall -- 28. MSCs for autoimmune diseases / Alan Tyndall and Chiara Bocelli -- 29. MSCs for induction of solid organ allograft acceptance / Marc Dahlke, Philipp Renner and Elke Eggenhofer -- 30. MSCc for gastrointestinal disorders / Maria Ester Bernardo, Angela Maria Cometa and Franco Locatelli -- 31. MSCs for cardiac repair / Amish N. Raval and Timothy A. Hacker -- 32. MSCs for treatment of acute lung injury / Vladimir B. Serikov, Anna Krasnodembskaya, Jae Wood Lee, Marlowe W. Eldridge and Michael A. Matthay -- 33. MSCs for diabetes / Luca Inverardi, Giacomo Lanzoni, Juan Dominguez-Bendala and Camillo Ricordi -- 34. MSCs for renal repair / Anna M. Gooch and Christof Westenfelder -- 35. MSCs for the treatment of stroke, spinal cord injury, and traumatic brain injury: from bench work to clinical trials / Bing Yang, Ramy El Khoury, and Sean I. Savitz -- 36. MSCs in reconstructive surgery / Summer E. Hanson and Michael L. Bentz -- 37. MSCs in orthopedic surgery / Summer E. Hanson and Nicholas H. Maassen -- 30. Adipose tissue-derived MSCs: moving to the clinic / Pedro P. Carvalho, Manuela E. Gomes, Rui L. Reis and Jeffrey M. Gimble.
- Metabolic pathway engineering handbook. 1st ed. v. 1-2, 2010.CRCnetBASEv. 2 CRCnetBASE[v. 1.] Fundamentals -- [v. 2.] Tools and applications.
- Methods in biobanking 2011Springer ProtocolsGenetic research and biobanks / D. Chalmers -- The need to downregulate: A minimal ethical framework for biobank research / M.G. Hansson -- Nordic biological specimen bank cohorts as basis for studies of cancer causes and control: Quality control tools for study cohorts with more than two million sample donors and 130,000 prospective cancers / E. Pukkala -- Biobanks collected for routine healthcare purposes: Build-up and use for epidemiologic research / J. Dillner and K. Andersson -- Biobanks and registers in epidemiologic research on cancer / E. Pukkala -- Study designs for biobank-based epidemiologic research on chronic diseases / E. Laara -- The European prospective investigation into cancer and nutrition biobank / P. Hainaut ... [et al.] -- The aids and cancer specimen resource / L.W. Ayers ... [et al.] -- Specific advantages of twin registries and biobanks / J. Kaprio -- The Swedish multi-generation register / A. Ekbom -- Multigenerational information: The example of the Icelandic genealogy database / H. Tulinius -- Creation of a new prospective research biobank: The example of HUNT3 / K. Hveem -- Best practices for establishing a biobank / G. Hallmans and J.B. Vaught -- Extraction, quantitation, and evaluation of function DNA from various sample types / M. Ivarsson and J. Carlson -- Cervical cytology biobanks as a resource for molecular epidemiology / M. Arbyn ... [et al.] -- Biobanking of fresh frozen tissue from clinical surgical specimens: Transport logistics, sample selection, and histologic characterization / J. Botling and P. Micke -- Protein extraction from solid tissue / C. Ericsson and M. Nister -- Collection and preservation of frozen microorganisms / R. Tedeschi and P. De Paoli -- Handling of solid brain tumor tissue for protein analysis / C. Ericsson and M. Nister -- Blood plasma handling for protein analysis / C. Ericsson and M. Nister -- Biobank informatics: Connecting genotypes and phenotypes / J.E. Litton -- A practical guide to constructing and using tissue microarrays / I. Chandler, R. Houlston and G. Landberg -- Breast cancer genomics based on biobanks / A. Forsti and K. Hemminki -- Monitoring, alarm, and data visualization service on sample preparing and sample storing devices in biobanks / H. Hauksdottir, K. Jonsdottir and A. Thorarinsson -- Fresh frozen tissue: RNA extraction and quality control / J. Botling and P. Micke.
- Methods in biotechnology v. 1-, 1997-Springer Protocols
- Methods in protein design 2013ScienceDirectComputational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides.
- MICADNCBI BookshelfThis searchable database is a collection of in vivo molecular imaging agents developed for positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), ultrasound (US), computed tomography (CT), and optical imaging. MICAD, a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, is being developed by NCBI, the National Center for Biotechnology Information".
- Microarray image analysis an algorithmic approach 2010CRCnetBASE
- Microarray image and data analysis theory and practice 2014CRCnetBASEMicroarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of microarrays, the book:Describes the key stages of image processing, gridding, segmentation, compression, quantification, and normalizationFeatures cutting-edge approaches to clustering, biclustering, and the reconstruction of regulatory networksCovers different ty.
- Microarray technology and its applications 2005Springerpt. 1. General microarray technologies -- pt. 2. DNA microarrays -- pt. 3. Protein microarrays -- pt. 4. Cell & tissue microarrays.
- Microarrays in inflammation 2008Springer
- Microdrop generation 2003CRCnetBASE
- Microinjection methods and applications 2009Springer ProtocolsExpression of exogenous mRNA in Xenopus laevis embryos for the study of cell cycle regulation / Jill C. Sible and Brian N. Wroble -- Use of luciferase chimaera to monitor PLC[zeta] expression in mouse eggs / Karl Swann ... [et al.] -- Analysis of 14-3-3 family member function in Xenopus embryos by microinjection of antisense morpholino oligos / Jeffrey M.S. Lau and Anthony J. Muslin -- A microinjectable biological system, the Xenopus oocyte, as an approach to understanding signal transduction protein function / Katia Cailliau and Edith Browaeys-Poly -- Combining microinjection and immunoblotting to analyse MAP kinase phosphorylation in single starfish oocytes and eggs / David J. Carroll and Wei Hua -- Analysis of signaling pathways in zebrafish development by microinjection / William H. Kinsey -- Protein inhibition by microinjection and RNA-mediated interference in tissue culture cells : complementary approaches to study protein function / Jane R. Stout, Rania S. Rizk, and Claire E. Walczak -- DNA delivery by microinjection for the generation of recombinant mammalian cell lines / Sebastien Chenuet ... [et al.] -- Bacteriophage [phi]C31 integrase mediated transgenesis in Xenopus laevis for protein expression at endogenous levels / Bryan G. Allen and Daniel L. Weeks -- Germline transformation of Caenorhabditis elegans by injection / Pavan Kadandale, Indrani Chatterjee, and Andrew Singson -- Quantitative microinjection of mouse oocytes and eggs / Douglas Kline -- Microinjection of follicle-enclosed mouse oocytes / Laurinda A. Jaffe ... [et al.] -- Functional studies of regulatory genes in the sea urchin embryo / Vincenzo Cavalieri, Maria Di Bernardo, and Giovanni Spinelli -- Exploring the cytoskeleton during intracytoplasmic sperm injection in humans / Vanesa Y. Rawe and Héctor Chemes -- Somatic cell nuclear transfer in the mouse / Satoshi Kishigami and Teruhiko Wakayama.
- MicroRNAs as tools in biopharmaceutical production 2012Springer"MicroRNAs are small, non-coding RNA molecules that interact with target mRNAs to modulate their translation. They are now recognized as widespread and critical regulators of gene expression in the cell. This book is aimed at both industry- and academic-based researchers in the Biopharmaceutical production space who wish to learn more about these fascinating molecules..."--Page  of cover.
- Microscopic techniques in biotechnology 2003Wileych. 1. Light Microscopy, p. 1-145 -- ch. 2. Electron Microscopy, p. 147-286 -- ch. 3. Other Microscopical Methods and their Application Potential, p. 287-319.
- Microspheres and microcapsules in biotechnology design, preparation, and applications 2013CRCnetBASE1. Microspheres for enzyme immobilization / Fei Gao, Yuxia Wang, and Guanghui Ma -- 2. Microspheres for cell culture / Weiqing Zhou, Guanghui Ma, and Zhiguo Su -- 3. Microcapsules for cell transplantation : design, preparation, and application / Guojun Lv, Ying Zhang, Mingqian Tan, Hongguo Xie, and Xiaojun Ma -- 4. Microspheres for the separation and refolding of proteins with an emphasis on particles made of agarose / Jan-Christer Janson -- 5. Microspheres for separation of bioactive small molecules / Fangling Gong, Guifeng Zhang, and Zhiguo Su -- 6. Microspheres for separation of PEG-modified biomolecules / Yongdong Huang, Yanqin Zhai, and Zhiguo Su -- 7. Microspheres for solid-phase organic synthesis / Jing Zhang and Zhiguo Su -- 8. Microspheres for solid-phase modification of proteins / Tao Hu and Zhiguo Su -- 9. Microspheres and microcapsules for protein drug delivery / Lianyan Wang, Tingyuan Yang, and Guanghui Ma -- 10. Micro/nanospheres for gene drug delivery / Jie Wu and Guanghui Ma -- 11. Microspheres for targeting delivery of anticancer drugs / Wei Wei, Zhanguo Yue, Hua Yue, and Guanghui Ma -- 12. Microspheres for targeting delivery to brain / Chen Jiang, Xinguo Jiang, Yang Liu, Kun Shao, and Rongqin Huang -- 13. Nano/microspheres in bioimaging and medical diagnosis / Xiaohui Li and Chunying Chen -- 14. Affinity nanoparticles for detection / Haruma Kawaguchi and Hiroshi Handa.
- Molecular biophysics for the life sciences 2013SpringerThis volume of the series Biophysics for the Life Sciences focuses on the conceptual framework and major research tools of contemporary molecular biophysics. It is designed to enable non-specialists -both students and professionals in other fields - to understand how these approaches can be used across the biosciences and in medicine, agriculture, biotechnology, pharmaceutical development and other fields. The scope of this volume is appropriate for advanced undergraduate and graduate courses in biophysics and biophysical chemistry. The book begins with an overview of the development of molecular biophysics and a brief survey of structural, physical, and chemical principles. Subsequent chapters written by experts present, with examples, the major experimental methods: optical spectroscopy, X-ray and neutron diffraction and scattering, nuclear magnetic resonance, electron paramagnetic resonance, mass spectrometry, and single molecule methods. The relationship between the biophysical properties of biological macromolecules and their roles as molecular machines is emphasized throughout and illustrated with three examples DNA helicases, rotary motor ATPases, and myosin.The concluding chapter discusses future prospects in X-ray and neutron scattering, mass spectrometry, and pharmaceutical development.
- Molecular breeding of woody plants proceedings of the International Wood Biotechnology Symposium (IWBS) held in Narita, Chiba, Japan, March 14-17, 2001 2001ScienceDirect
- Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. This handbook provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.
- Molecular diagnostics-- promises and possibilities 2010Springer
- Molecular diagnostics. 2nd ed. 2010ScienceDirectChapter 1. Molecular Diagnostics: Past, Present, and Future / George P. Patrinos, Wilhelm J. Ansorge -- Chapter 2 . Allele-Specific Mutation Detection / Aglaia Athanassiadou, Eleana F. Stavrou, Adamandia Papachatzopoulou, George P. Patrinos -- Chapter 3. Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation / Chinh T. Bui, Emmanuelle Nicolas, Georgina Sallmann, Maria Chiotis, Andreana Lambrinakos, Kylee Rees, Ian Trounce, Richard G.H. Cotton, Lauryn Blakesley, Andrew K. Godwin, Anthony T. Yeung -- Chapter 4. Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis / Panayiotis G. Menounos, George P. Patrinos -- Chapter 5. Capillary Electrophoresis / Anja Bosserhoff, Claus Hellerbrand -- Chapter 6. Temperature and Denaturing Gradient Gel Electrophoresis / Hartmut Peters, Peter N. Robinson -- Chapter 7. Real-Time Polymerase Chain Reaction / Lut Overbergh, Anna-Paula Giulietti, Dirk Valckx, Chantal Mathieu -- Chapter 8 - Pyrosequencing / Sharon Marsh -- Chapter 9. Application of Padlock and Selector Probes in Molecular Medicine / Mats Nilsson, Chatarina Larsson, Johan Stenberg, Jenny Göransson, Ida Grundberg, Magnus Isaksson, Tim Conze, Sara Henriksson -- Chapter 10. Molecular Cytogenetics in Molecular Diagnostics / Holger Tönnies -- Chapter 11. Analysis of Human Splicing Defects Using Hybrid Minigenes / Franco Pagani, Francisco E. Baralle -- Chapter 12. Detection of Genomic Duplications and Deletions / Graham R. Taylor, Carol A. Delaney -- Chapter 13. Multiplex Ligation-Dependent Probe Amplification (MLPA) and Methylation-Specific (MS)-MLPA: Multiplex Detection of DNA/mRNA Copy Number and Methylation Changes / Eline M. Sepers, Jan P. Schouten -- Chapter 14. Molecular Techniques for DNA Methylation Studies / Jörg Tost, Ivo G. Gut -- Chapter 15. High-Resolution Melting Curve Analysis for Molecular Diagnostics / Jared S. Farrar, Gudrun H. Reed, Carl T. Wittwer -- Chapter 16. DNA Microarrays and Genetic Testing / Lars Dyrskjøt, Karina Dalsgaard-Sørensen, Marie Stampe-Ostenfeld, Karin Birkenkamp-Demtroder, Kasper Thorsen, Claus L. Andersen, Mogens Kruhøffer, Jens L. Jensen, Torben F. Ørntoft -- Chapter 17. Arrayed Primer Extension Microarrays for Molecular Diagnostics / Neeme Tonisson, Eneli Oitmaa, Kaarel Krjutskov, Janne Pullat, Ilona Lind, Merike Leego, Ants Kurg, Andres Metspalu -- Chapter 18. Application of Proteomics to Disease Diagnostics / Samir Hanash, Ji Qiu, Vitor Faca -- Chapter 19. RNA-Based Variant Detection: The Protein Truncation Test / Johan T. den Dunnen -- Chapter 20. Protein Diagnostics by Proximity Ligation: Combining Multiple Recognition and DNA Amplification for Improved Protein Analyses / Karl-Johan Leuchowius, Ola Söderberg, Masood Kamali-Moghaddam, Malin Jarvius, Irene Weibrecht, Katerina Pardali, Ulf Landegren -- Chapter 21. Mass Spectrometry and its Applications to Functional Proteomics / Thomas Köcher, Giulio Superti-Furga -- Chapter 22. Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Clinical Care / Minoli Perera, Federico Innocenti -- Chapter 23. Nutrigenomics: Integrating Genomic Approaches into Nutrition Research / Lynette R. Ferguson, Martin Philpott, Matthew P.G. Barnett -- Chapter 24. Novel Next-Generation DNA Sequencing Techniques for Ultra High-Throughput Applications in Bio-Medicine / Wilhelm J. Ansorge -- Chapter 25. Locus-Specific and National/Ethnic Mutation Databases: Emerging Tools for Molecular Diagnostics / George P. Patrinos -- Chapter 26. Molecular Diagnostic Applications in Forensic Science / Bruce Budowle, John V. Planz, Rowan Campbell, Arthur J. Eisenberg -- Chapter 27. Mass Disaster Victim Identification Assisted by DNA Typing / Daniel Corach -- Chapter 28. Detection of Highly Pathogenic Viral Agents: Implications for Therapeutics, Vaccines and Biodefense / Kylene Kehn-Hall, Sina Bavari -- Chapter 29. Identification of Genetically Modified Organisms / Farid E. Ahmed -- Chapter 30. Molecular Diagnostics and Comparative Genomics in Clinical Microbiology / Alex van Belkum -- Chapter 31. Genetic Monitoring of Laboratory Rodents / Jean-Louis Guénet, Fernando J. Benavides -- Chapter 32. Safety Analysis in Retroviral Gene Therapy: Identifying Virus Integration Sites in Gene-Modified Cells / Stephanie Laufs, Luisa Schubert, Patrick Maier, W. Jens Zeller, Stefan Fruehauf -- Chapter 33. Preimplantation Genetic Diagnosis / Martine de Rycke, Karen Sermon -- Chapter 34. Automated DNA Hybridization and Detection / Bert Gold -- Chapter 35. The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays / Piotr Grodzinski, Michael Ward, Robin Liu, Kathryn Scott, Saul Surrey, Paolo Fortina -- Chapter 36. Human Gene Patents and Genetic Testing / Timothy Caulfield, Yann Joly -- Chapter 37. Genetic Counseling and Ethics in Molecular Diagnostics / Mary Petrou -- Chapter 38. Genetic Testing and Psychology / Andrea Farkas Patenaude -- Chapter 39. General Considerations Concerning Safety in Biomedical Research Laboratories / William E. Grizzle, Walter C. Bell, Jerry Fredenburgh -- Chapter 40. Quality Management in the Laboratory / David Burnett.
- Molecular imaging and contrast agent databaseNCBI BookshelfThis searchable database is a collection of in vivo molecular imaging agents developed for positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), ultrasound (US), computed tomography (CT), and optical imaging. MICAD, a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, is being developed by NCBI, the National Center for Biotechnology Information".
- Biomolecule/nanomaterial hybrid systems for nanobiotechnology -- Superresolution optical fluctuation imaging (SOFI) -- Application of nanoparticles for the detection and sorting of pathogenic bacteria by flow-cytometry -- Advancing nanostructured porous si-based optical transducers for label free bacteria detection -- Gold fibers as a platform for biosensing -- Surface-enhanced raman spectroscopy of organic molecules adsorbed on metallic nanoparticles -- Quantum dots and fluorescent protein FRET-based biosensors -- Semiconductor quantum dots as FRET acceptors for multiplexed diagnostics and molecular ruler application -- Assembly and microscopic characterization of DNA origami structures -- DNA nanotechnology -- Role of carbohydrate receptors in the macrophage uptake of dextran-coated iron oxide nanoparticles -- Toxicity of gold nanoparticles on somatic and reproductive cells -- Ultrasound activated nano-encapsulated targeted drug delivery and tumour cell poration -- Ultrasound mediated localized drug delivery -- Sonochemical proteinaceous microspheres for wound healing -- Alendronate liposomes for antitumor therapy: activation of [gamma] [delta] T cells and inhibition of tumor growth.
- NanobiotechnologyWileyv. 2, 2007 Wiley[v. 1]. Concepts, applications, and perspectives -- 1 . Biocompatible inorganic devices / Thomas Sawitowski -- 2. Microfluidics meets nano : lab-on-a-chip devices and their potential for nanobiotechnology / Holger Bartos, Friedrich Götz, and Ralf-Peter Peters -- 3. Microcontact printing of proteins / Emmanuel Delamarche -- 4. Cell-nanostructure interactions / Joachim P. Spatz -- 5. Defined networks of neuronal cells in vitro / Andreas Offenhäusser and Angela K. Vogt -- 6. S-Layers / Uwe B. Sleytr ... [et al.] -- 7. Engineered nanopores / Hagan Bayley ... [et al.] -- 8. Genetic approaches to programmed assembly / Stanley Brown -- 9. Microbial nanoparticle production / Murali Sastry ... [et al.] -- 10. Magnetosomes : nanoscale magnetic iron minerals in bacteria / Richard B. Frankel and Dennis A. Bazylinski -- 11. Bacteriorhodopsin and its potential in technical applications / Norbert Hampp and Dieter Oesterhelt -- 12. Polymer Nanocontainers / Alexandra Graff ... [et al.] -- 13. Biomolecular motors operating in engineered environments / Stefan Diez, Jonne H. Helenius, and Jonathon Howard -- 14. Nanoparticle-biomaterial hybrid systems for bioelectronic devices and circuitry / Eugenii Katz and Itamar Willner -- 15. DNA-protein nanostructures / Christof M. Neimeyer -- 16. DNA-templated electronics / Erez Braun and Uri Sivan -- 17. Biomimetic fabrication of DNA-based metallic nanowires and networks / Michael Mertig and Wolfgang Pompe -- 18. Mineralization in nanostructured biocompartments : biomimetic ferritins for high-density data storage / Eric L. Mayes and Stephen Mann -- 19. DNA-gold nanoparticle conjugates / C. Shad Thaxton and Chad A. Mirkin -- 20. DNA nanostructures for mechanics and computing : nonlinear thinking with life's central molecule / Nadrian C. Seeman -- 21. Nanoparticles as non-viral transfection agents / M.N.V. Ravi Kumar, Udo Bakowsky, and Claus-Michael Lehr -- 22. Luminescent quantum dots for biological labeling / Xiaohu Gao and Shuming Nie -- 23. Nanoparticle molecular labels / James F. Hainfeld, Richard D. Powell, and Gerhard W. Hacker -- 24. Surface biology : analysis of biomolecular structure by atomic force microscopy and molecular pulling / Emin Oroudjev, Signe Danielsen and Helen G. Hansma -- 25. Force spectroscopy / Markus Seitz -- 26. Biofunctionalized nanoparticles for surface-enhanced raman scattering and surface plasmon resonance / Mahnaz El-Kouedi and Christine D. Keating -- 27. Bioconjugated silica nanoparticles for bioanalytical applications / Timothy J. Drake, Xiaojun Julia Zhao, and Weihong Tan. -- v. 2. More concepts and applications -- Part I. Self-Assembly and Nanoparticles: Novel Principles -- ch. 1. Self-Assembled Artificial Transmembrane Ion Channels / Mary S. Gin, Emily G. Schmidt and Pinaki Talukdar, p. 1-15 -- ch. 2. Self-Assembling Nanostructures from Coiled-Coil Peptides / Maxim G. Ryadnov and Derek N. Woolfson, p. 17-38 -- ch. 3. Synthesis and Assembly of Nanoparticles and Nanostructures Using Bio-Derived Templates / Erik Dujardin and Stephen Mann, p. 39-63 -- ch. 4. Proteins and Nanoparticles: Covalent and Noncovalent Conjugates / Rochelle R. Arvizo, Mrinmoy De and Vincent M. Rotello, p. 65-78 -- ch. 5. Self-Assembling DNA Nanostructures for Patterned Molecular Assembly / Thomas H. LaBean, Kurt V. Gothelf and John H. Reif, p. 79-97 -- ch. 6. Biocatalytic Growth of Nanoparticles for Sensors and Circuitry / Ronan Baron, Bilha Willner and Itamar Willner, p. 99-121 -- Part II. Nanostructures for Analytics -- ch. 7. Nanoparticles for Electrochemical Bioassays / Joseph Wang, p. 123-140 -- ch. 8. Luminescent Semiconductor Quantum Dots in Biology / Thomas Pons, Aaron R. Clapp, Igor L. Medintz and Hedi Mattoussi, p. 141-157 -- ch. 9. Nanoscale Localized Surface Plasmon Resonance Biosensors / Katherine A. Willets, W. Paige Hall, Leif J. Sherry, Xiaoyu Zhang, Jing Zhao and Richard P. Van Duyne, p. 159-173 -- ch. 10. Cantilever Array Sensors for Bioanalysis and Diagnostics / Hans Peter Lang, Martin Hegner and Christoph Gerber, p. 175-195 -- ch. 11. Shear-Force-Controlled Scanning Ion Conductance Microscopy / Tilman E. Schäffer, Boris Anczykowski, Matthias Böcker and Harald Fuchs, p. 197-212 -- ch. 12. Label-Free Nanowire and Nanotube Biomolecular Sensors for In-Vitro Diagnosis of Cancer and other Diseases / James R. Heath, p. 213-232 -- ch. 13. Bionanoarrays / Rafael A. Vega, Khalid Salaita, Joseph J. Kakkassery and Chad A. Mirkin, p. 233-259 -- Part III. Nanostructures for Medicinal Applications --. ch. 14. Biological Barriers to Nanocarrier-Mediated Delivery of Therapeutic and Imaging Agents, p. 261-284 / Rudy Juliano -- ch. 15. Organic Nanoparticles: Adapting Emerging Techniques from the Electronics Industry for the Generation of Shape-Specific, Functionalized Carriers for Applications in Nanomedicine / Larken E. Euliss, Julie A. DuPont and Joseph M. DeSimone, p. 285-303 -- ch. 16. Poly(amidoamine Dendrimer-Based Multifunctional Nanoparticles / Thommey P. Thomas, Rameshwer Shukla, Istvan J. Majoros, Andrzej Myc and James R. Baker, p. 305-319 -- ch. 17. Nanoparticle Contrast Agents for Molecular Magnetic Resonance Imaging / Young-Wook Jun, Jae-Hyun Lee and Jinwoo Cheon, p. 321-346 -- ch. 18. Micro- and Nanoscale Control of Cellular Environment for Tissue Engineering / Ali Khademhosseini, Yibo Ling, Jeffrey M. Karp and Robert Langer, p. 347-364 -- ch. 19. Diagnostic and Therapeutic Targeted Perfluorocarbon Nanoparticles / Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza and Samuel A. Wickline, p. 365-380 -- Part IV. Nanomotors -- ch. 20. Biological Nanomotors / Manfred Schliwa, p. 381-399 -- ch. 21. Biologically Inspired Hybrid Nanodevices / David Wendell, Eric Dy, Jordan Patti and Carlo D. Montemagno, p. 401-418.
- Nanobiotechnology protocols. Second edition. [2nd ed.] 2013Springer ProtocolsHigh-aspect-ratio gold nanorods : their synthesis and application to image cell-induced strain fields in collagen films / Davin J. Chernak ... [et al.] -- Imaging intracellular quantum dots : fluorescence microscopy and transmission electron microscopy / Craig J. Szymanski ... [et al.] -- Imaging of cell populations in atherosclerosis using quantum dot nanocrystals / Joshua R. Trantum and Ashwath Jayagopal -- Imaging of endothelial progenitor cell subpopulations in angiogenesis using quantum dot nanocrystals / Joshua M. Barnett, John S. Penn, and Ashwath Jayagopal -- Imaging single synaptic vesicles in mammalian central synapses with quantum dots / Qi Zhang -- Quantum dot-based single-molecule microscopy for the study of protein dynamics / Jerry C. Chang and Sandra J. Rosenthal -- Three-dimensional molecular imaging with photothermal optical coherence tomography / Melissa C. Skala ... [et al.] -- Detecting respiratory syncytial virus using nanoparticle-amplified immuno-PCR / Jonas W. Perez ... [et al.] -- Gold nanoparticle-oligonucleotide conjugates for the profiling of malignant melanoma phenotypes / John W. Stone ... [et al.] -- Methods for isolating RNA sequences capable of binding to or mediating the formation of inorganic materials / Carly Jo Carter, Alina Owczarek, and Daniel L. Feldheim -- Single-walled carbon nanotube-mediated small interfering RNA delivery for gastrin-releasing peptide receptor silencing in human neuroblastoma / Jingbo Qiao ... [et al.] -- Amino acid mediated linear assembly of au nanomaterials / Manish Sethi and Marc R. Knecht -- Enzyme-gold nanoparticle bioconjugates : quantification of particle stoichiometry and enzyme specific activity / Jacqueline D. Keighron and Christine D. Keating -- In vivo testing for gold nanoparticle toxicity / Carrie A. Simpson, Brian J. Huffman, and David E. Cliffel -- Methods for studying toxicity of silica-based nanomaterials to Living Cells / Yang Zhao ... [et al.].
- Nanocarrier technologies frontiers of nanotherapy 2006Springer
- Nanomaterial interfaces in biology methods and protocols 2013Springer ProtocolsPreparation of 2 nm gold nanoparticles for in vitro and in vivo applications / Daniel F. Moyano, Bradley Duncan, and Vincent M. Rotello -- DNA conjugation to nanoparticles / Sunho Park -- Conjugation of nanoparticles to proteins / Marie-Eve Aubin-Tam -- Water-solubilization and functionalization of semiconductor quantum dots / Christina M. Tyrakowski, Adela Isovic, and Preston T. Snee -- Synthesizing and modifying peptides for chemoselective ligation and assembly into quantum dot-peptide bioconjugates / W. Russ Algar ... [et al.] -- Reliable methods for silica coating of au nanoparticles / Isabel Pastoriza-Santos and Luis M. Liz-Marzán -- Surface modifications by polymers for biomolecule conjugation / Laura Sola ... [et al.] -- Functionalization protocols of silicon micro/nano- mechanical biosensors / Francesca Frascella and Carlo Ricciardi -- Stability and aggregation assays of nanoparticles in biological media / James Chen Yong Kah -- Electrochemical measurements of DNA melting on surfaces / Irina Belozerova, Dongbiao Ge, and Rastislav Levicky -- Formation and characterization of the nanoparticle-protein corona / Marco P. Monopoli ... [et al.] -- Electrophoretic implementation of the solution-depletion method for measuring protein adsorption, adsorption kinetics, and adsorption competition among multiple proteins in solution / Hyeran Noh ... [et al.] -- Hyperspectral microscopy for characterization of gold nanoparticles in biological media and cells for toxicity assessment / Christin Grabinski, John Schlager, and Saber Hussain -- Immunocytochemistry, electron tomography, and energy dispersive x-ray spectroscopy (EDXS) on cryosections of human cancer cells doped with stimuli responsive polymeric nanogels loaded with iron oxide nanoparticles / Roberto Marotta ... [et al.] -- Zwitterion siloxane to passivate silica against nonspecific protein adsorption / Zaki G. Estephan and Joseph B. Schlenoff -- Preparation and characterization of DNA block copolymer assemblies loaded with nanoparticles / Xi-Jun Chen, Robert J. Hickey, and So-Jung Park -- Polyaspartic acid coated iron oxide nanoprobes for PET/MRI imaging / Taku Cowger and Jin Xie -- Ligand synthesis and passivation for silver and large gold nanoparticles for single-particle-based sensing and spectroscopy / Daniel Montiel ... [et al.] -- Noncovalent intracellular drug delivery of hydrophobic drugs on au NPs / Tennyson Doane and Clemens Burda -- Modification of carbon nanotubes for gene delivery vectors / Victor Ramos-Perez ... [et al.] -- Lipid-based nanoparticles as nonviral gene delivery vectors / Daniele Pezzoli ... [et al.] -- Stabilizing gold nanoparticle bioconjugates in physiological conditions by PEGylation / Joan Comenge and Víctor F. Puntes.
- Micro and nano systems in biomedicine and drug delivery / Nesrin Hasirci -- Newlipid- and glycolipid-based nanosystems for targeted gene delivery: cholenims, glycoclips, and chitosan / R.I. Zhdanov ... [et. al] -- Artificial implants - new developments and associated problems / Abdelwahab Omri -- Niosomes as nanocarrier systems / Nefise Ozlen Sahin -- Starch - a potential biomaterial for biomedical application / Lovedeep Kaur, Jaspreet Singh, Qiang Liu -- Alternative applications for drug delivery: nasal and pulmonary routes / A. Yekta Ozer -- An overview of lipsome-derived nanocarrier technologies / M. Reza Mozafari, Kianoush Khosravi-Darani -- Uptake studies of free and liposomal sclareol by MCF-7 and H-460 human cancer cell lines / Agnes Paradissi ... [et. al] -- Release advantages of a liposomal dendrimer- doxorubicin complex, over conventional liposomal formulation of doxorubicin / Aristarchos Papagiannoros, Costas Demetzos -- Applications of light and electron microscopic techniques in liposome research / A. Yekta Ozer.
- Nanoscale technology in biological systems 2005CRCnetBASE
- Near-infrared applications in biotechnology 2001CRCnetBASE
- Theoretical considerations on animal models / Poindron, P., Callizot, N., Piguet, P. -- Mouse models with motor neuron defects as a tool for deciphering amyotrophic lateral sclerosis. Applications, limits, and future challenges / Echaniz-Laguna, A. ... [et al.] -- A chronic relapsing animal model for multiple sclerosis. Myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis in dark agouti rats / Kinter, J., Zeis, T., Schaeren-Wiemers, N. -- Occlusion of the middle cerebral artery in rats. Refinement of an animal model for human stroke / Cam, E. ... [et al.] -- Pyridoxine-induced peripheral neuropathy. Animal models and uses / Callizot, N., Poindron, P. -- A dopamine-sensitive inherited motor syndrome linked to the frissonnant mutation / Callizot, N., Guenet, J.-L., Poindron, P.
- New frontiers of network analysis in systems biology 2012SpringerGene Expression Profiling and Regulatory Networks in Single Cells / Fumio Arai, Kentaro Hosokawa, Yoshiko Matsumoto, Hirofumi Toyama and Toshio Suda -- Cell Fate Regulatory Networks / Sonya J. Ridden and Ben D. MacArthur -- Noise in Regulatory Networks / Srinandan Dasmahapatra -- Generalised Modelling in Systems Biology / Thilo Gross -- Relative Quantification Mass Spectrometry Using iTRAQ Isobaric Tags / Richard D. Unwin, Emma Carrick and Anthony D. Whetton -- Deciphering Protein Complexes and Protein Interaction Networks for Stem Cell Pluripotency / Jianlong Wang -- Omics Era in Stem Cell Research: Data Integration of Multi-regulatory Layers / Ana Sevilla, Benjamin Trinite and Ihor R. Lemischka -- High Throughput Affinity Purification and Mass Spectrometry to Determine Protein Complex Interactions / Anna Malovannaya, Rainer B. Lanz, Bert W. O'Malley and Jun Qin -- Network Pharmacology to Aid the Drug Discovery Process / Ruth Dannenfelser, Huilei Xu, Catherine Raimond and Avi Ma'ayan -- What Can Networks Do for You? / Bernhard M. Schuldt, Franz-Josef Müller and Andreas A. Schuppert.
- Overview: developments in DNA sequencing / Keith R. Mitchelson ... [et al.] -- Chip capillary electrophoresis and total genetic analysis systems / Quiang Xiong and Jing Cheng -- Comparative sequence analysis by MALDI-TOF mass spectrometry: utilizing the known to discover the new / Mathias Ehrich, Franz Hillenkamp, and Dirk van den Boom -- Advances in dye-nucleotide conjugate chemistry for DNA sequencing / Shiv Kumar and Carl W. Fuller -- The 454 life sciences picoliter sequencing system / Marcel Margulies ... [et al.] -- An integrated system for DNA sequencing by synthesis / John R. Edwards, Dae Hyun Kim, and Jingyue Ju -- Single-molecule fluorescence microscopy and its applications to single-molecule sequencing by cyclic synthesis / Benedict Hebert and Ido Braslavsky -- Rapid DNA sequencing by direct nanoscale reading of nucleotide bases on individual DNA chains / James Weifu Lee and Amit Meller -- A single molecule system for whole genome analysis / Shiguo Zhou, Jill Herschleb, and David C. Schwartz -- Sequencing aided by mutagenesis facilitates the de novo sequencing of megabase DNA fragments by short read lengths / Jonathan M. Keith ... [et al.] -- Genome sequencing and assembly / Annette McGrath -- Valid recovery of nucleic acid sequence information from high contamination risk samples: ancient DNA and environmental DNA / George A. Kowalchuk ... [et al.].
- Hippocampal slice cultures / Förster, E., Bartos, M., Zhao, S. -- Protocol for the primary culture of cortical neurons / Gonthier, B. ... [et al.] -- A new technique to control the architecture of neuronal networks in vitro / Wyart, C. ... [et al.] -- Organotypic cultures of the rat retina / Hofmann, H.-D. ... [et al.] -- Cerebellar slice cultures / Kapfhammer, J.P. -- Culture of dissociated hippocampal neurons / Rigato, F. -- Improved methods for culturing rat and mouse motor neurons. Their applications / Guettier-Sigrist, S. ... [et al.] -- Characterization of long-term cultured cell lines of murine microglia called MAMI. The case for MAMI-96 cell line / Laporte, V. ... [et al.].
- Nuclear reprogramming and stem cells 2011SpringerAnnotation Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mechanisms that drive disease aetiology the research is realistically opening the doors for development of targeted and personalized therapeutic applications that many considered, until recently, to be nothing more that a far fetched dream. This volume provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years. Since the early 1950s a small number of notable experiments have provided significant impetus to the field, primarily the demonstration of reprogramming ability, first by the complex cytoplasmic milieu that constitutes the amphibian egg, then that of the mammalian egg, and finally that of the mammalian embryonic stem cell. Most recently, the demonstration that a limited pool of defined molecules is capable of reprogramming a multitude of cell types has provided massive impetus and facilitated transition towards realistic therapeutic application. We have therefore reproduced some of the key articles that elegantly document these dramatic stages of development of the field in an inclusive appendix to the book, for the benefit of readers keen to investigate the history of how the field of stem cell biology has evolved. Owing to the ever broadening nature of this field, and the incredible rate at which it is evolving, the main content of this volume focuses on areas that have shown significant movement in recent years, are most likely to translate into personalized therapeutic application, and thus provide greatest potential for significant impact on human health in the not too distant future. We recognize that research into many other disease states and cell types are all equally worthy of discussion. We would therefore like to acknowledge those researchers involved whose work we have not been able to include in this volume. Nuclear Reprogramming and Stem Cells will serve as a valuable resource for all researchers in the field of stem cell biology, including those just setting out on their career path as well as those already established in the field.
- Nutraceutical and specialty lipids and their co-products 2006CRCnetBASE1. Nutraceutical and Specialty Lipids / Fereidoon Shahidi and S.P.J.N. Senanayake -- 2. Medium-Chain Triacylglycerols / Yaakob B. Che Man and Marina Abdul Manaf -- 3. Cereal Grain Oils / Roman Przybylski -- 4. Fruit Seed Oils / Liangli Yu, John W. Parry, and Kequan Zhou -- 5. Minor Specialty Oils / Frank D. Gunstone -- 6. Sphingolipids / Fang Fang, Hang Chen, Chi-Tang Ho, and Robert T. Rosen -- 7. Modification and Purification of Sphingolipids and Gangliosides / Scott Bloomer -- 8. Hydroxy Fatty Acids / Thomas A. McKeon, Charlotta Turner, Xiaohua He, Grace Chen, and Jiann-Tsyh Lin -- 9. Tree Nut Oils and Byproducts: Compositional Characteristics and Nutraceutical Applications / Fereidoon Shahidi and H. Miraliakbari -- 10. Gamma-Linolenic Acid (GLA) / Yao-wen Huang and Chung-yi Huang -- 11. Diacylglycerols (DAGs) and their Mode of Action / Brent D. Flickinger -- 12. Conjugated Linoleic Acids (CLAs): Food, Nutrition, and Health / Bruce A. Watkins and Yong Li -- 13. Occurrence of Conjugated Fatty Acids in Aquatic and Terrestrial Plants and their Physiological Effects / Bhaskar Narayan, Masashi Hosokawa, and Kazuo Miyashita -- 14. Marine Conjugated Polyunsaturated Fatty Acids / Yasushi Endo, Si-Bum Park, and Kenshiro Fujimoto -- 15. Marine Oils: Compositional Characteristics and Health Effects / Fereidoon Shahidi and H. Miraliakbari -- 16. Single-Cell Oils as Sources of Nutraceutical and Specialty Lipids: Processing Technologies and Applications / S.P.J.N. Senanayake and Jaouad Fichtali -- 17. Emulsions for the Delivery of Nutraceutical Lipids / Karlene S.T. Mootoosingh and Dérick Rousseau -- 18. Lipid Emulsions for Total Parenteral Nutrition (TPN) Use and as Carriers for Lipid-Soluble Drugs / Hu Liu and Lili Wang -- 19. Modified Oils / Frank D. Gunstone -- 20. Fat Replacers: Mimetics and Substitutes / Barry G. Swanson -- 21. Application of Functional Lipids in Foods / Charlotte Jacobsen, Maike Timm-Heinrich, and Nina Skall Nielsen -- 22. Application of Multistep Reactions with Lipases to the Oil and Fat Industry / Yuji Shimada, Toshihiro Nagao, and Yomi Watanabe -- 23. Structure-Related Effects on Absorption and Metabolism of Nutraceutical and Specialty Lipids / Armand B. Christophe -- 24. Lipid Oxidation in Specialty Oils / Karen Schaich -- 25. Trans Fatty Acids in Specialty Lipids / G.R. List, R.O. Adlof, and J.W. King -- 26. Tocopherols and Tocotrienols as Byproducts of Edible Oil Processing / Vitamin E: A New Perspective Andreas M. Papas -- 27. Plant Sterols and Steryl Esters in Functional Foods and Nutraceuticals / Nikolaus Weber and Kumar D. Mukherjee -- 28. Phospholipids/Lecithin: A Class of Nutraceutical Lipids / Frank T. Orthoefer and G.R. List -- 29. Centrifugal Partition Chromatography (CPC) as a New Tool for Preparative-Scale Purification of Lipid and Related Compounds / Udaya Wanasundara and Paul Fedec -- 30. Oilseed Medicinals: Applications in Drugs and Functional Foods / Robert D. Reichert.
- Omics for personalized medicine 2013SpringerOmics for Personalized Medicine will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.
- Optical techniques in regenerative medicine 2014CRCnetBASE"This book is focused on the optical techniques that can be applied to regenerative medicine, including optical coherence tomography, acousto-optic imaging, Raman spectroscopy, machine vision, polarized light imaging, fibre optic sensors, second harmonic generation, multi-photon microscopy, coherent anti-Stokes Raman scattering, and polarized light imaging. It covers applications both in fundamental research and in the regenerative medicine industry for tissue engineering products. Each chapter gives an overview of a particular technique, its advantages and limitations in terms of structural and functional information provided, and examples of applications in regenerative medicine. The book provides a practical guide to the most appropriate techniques for a given application. It also offers a summary of major recent advances, such as use of machine vision for tracking growth of three-dimensional constructs in bioreactors and polarization sensitive optical coherence tomography for monitoring collagen alignment in cartilage growth"--Provided by publisher.
- Organ regeneration methods and protocols 2013Springer Protocols1. Isolation and characterization of human adipose-derived stem cells for use in tissue engineering / Benjamin M. Buehrer and Bentley Cheatham -- 2. Isolation of smooth muscle cells from bladder for generation of engineered urologic organs / Darell W. McCoy -- 3. Isolation of urothelial cells from bladder tissue / Namrata Sangha -- 4. Isolation of pulsatile cell bodies from esophageal tissue / John W. Ludlow, Joydeep Basu, Christopher W. Genheimer, Kelly I. Guthrie, and Namrata Sangha -- 5. Cell isolation through whole-liver perfusion and preparation of hepatocytes for cytochrome P450 analysis / Sonya O. Meheux -- 6. Ex vivo culture and separation of functional renal cells / Andrew T. Bruce, Kelly I. Guthrie, and Rusty Kelley -- 7. Isolation and myogenic differentiation of mesenchymal stem cells for urologic tissue engineering / Rongpei Wu, Guihua Liu, Shantaram Bharadwaj and Yuanyuan Zhang -- 8. Xeno-free adaptation and culture of human pluripotent stem cells / Tori Sampsell-Barron -- 9. Reverse engineering life : physical and chemical mimetics for controlled stem cell differentiation into cardiomyocytes / Gary R. Skuse and Kathleen A. Lamkin-Kennard -- 10. Phenotypic analysis of bioactive cells for application in regenerative medicine / Teresa Bora Burnette and Andrew T. Bruce -- 11. Preparation and evaluation of natural scaffold materials for kidney regenerative applications / Monica A. Serban, Toyin A. Knight, and Richard G. Payne -- 12. Rapid production of autologous fibrin hydrogels for cellular encapsulation in organ regeneration / Adelola O. Oseni, Peter E. Butler, and Alexander M. Seifalian -- 13. Electrospinning tubular scaffolds with tissue-like mechanical properties and biomimetic surface features / Scott Rapoport -- 14. Design, fabrication, and preparation of synthetic scaffolds for urologic tissue engineering / Richard G. Payne and Toyin A. Knight -- 15. Characterization of a PGA-based scaffold for use in a tissue-engineered neo-urinary conduit / Toyin A. Knight and Richard G. Payne -- 16. Migration assay to evaluate cellular interactions with biomaterials for tissue engineering/regenerative medicine applications / Kelly I. Guthrie, Namrata Sangha, Christopher W. Genheimer, Joydeep Basu, and John W. Ludlow -- 17. Care of rodent models used for preclinical evaluation of tissue-engineered/regenerative medicine product candidates / Kim L. Mihalko -- 18. Bioreactor design considerations for hollow organs / Jeff Fish, Craig Halberstadt, Darell W. McCoy and Neil Robbins -- 19. Construction of a multicoaxial hollow fiber bioreactor / Randall McClelland, Katherine Tech, and Jeffrey M. Macdonald -- 20. Isolation of human cadaveric pancreatic islets for clinical transplantation / Craig Halberstadt, Deana Williams, and Paul Gores -- 21. Microencapsulation of pancreatic islets for use in a bioartificial pancreas / Emmanuel C. Opara, John P. McQuilling, and Alan C. Farney -- 22. Bioengineered skin substitutes / Pedro Lei, Hui You, and Stelios T. Andreadis -- 23. Formulation of selected renal cells for implantation into a kidney / Craig Halberstadt, Neil Robbins, Darrell W. McCoy, Kelly I. Guthrie, Andrew T. Bruce, Toyin A. Knight and Richard G. Payne -- 24. Human liver bioengineering using a whole liver decellularized bioscaffold / Pedro M. Baptista, Dipen Vyas, Emma Moran, Zhan Wang and Shay Soker -- 25. A "living bioreactor" for the production of tissue-engineered small intestine / Daniel E. Levin, Frederic G. Sala, Erik R. Barthel, Allison L. Speer, Xiaogang Hou, Yasuhiro Torshima and Tracy C. Grikscheit -- 26. Tissue engineering of esophagus and small intestine in rodent injury models / Joydeep Basu, Kim L. Mihalko, Elias A. Rivera, Kelly I. Guthrie, Christopher W. Genheimer, Namrata Sangha and John W. Ludlow -- 27. Scanning electron microscopy evaluation of endothelialized tissue-engineered constructs / Sandra L. Johnson -- 28. Genotypic and phenotypic analysis of in vivo tissue regeneration in an animal model / Christopher W. Genheimer -- 29. Histological evaluation of tissue regeneration using biodegradable scaffold seeded by autologous cells for tubular/hollow organ applications / Elias A. Rivera and Manuel J. Jayo.
- PCR cloning protocols. 2nd ed. 2002Springer Protocols
- Phage display in biotechnology and drug discovery 2005CRCnetBASE
- Pharmaceutical biotechnology 2009SpringerTranslational medicine: a paradigm shift in modern drug discovery and development: the role of biomarkers / Mark Day, J. Lynn Rutkowski, and Giora Z. Feuerstein -- Natural products in drug discovery: present status and perspectives / Gabriella Molinari -- Protein pharmaceuticals: discovery and preclinical development / Davinder S. Gill -- The role of nanobiotechnology in drug discovery / Kewal K. Jain -- Conotoxin venom peptide therapeutics / Richard J. Lewis -- Shark novel antigen receptors: the next generation of biologic therapeutics? / Caroline Barelle, Davinder Gill, and Keith Charlton -- Immune interventions of human diseases through toll-like receptors / Cevayir Coban, Ken J. Ishii, and Shizuo Akira -- Genome-based vaccine development: a short cut for the future / Danilo Gomes Moriel ... [et al.] -- The antigenome: from protein subunit vaccines to antibody treatments of bacterial infections? / Carmen Giefing, Eszter Nagy, and Alexander von Gabain -- HSV as a vector in vaccine development and gene therapy / Peggy Marconi ... [et al.] -- Virus-like particles as a vaccine delivery system: myths and facts / Polly Roy and Rob Noad -- Applications of bacterial ghosts in biomedicine / Petra Lubitz, Ulrike Beate Mayr, and Werner Lubitz -- Immune modulators with defined molecular targets: cornerstone to optimize rational vaccine design / Thomas Ebensen and Carlos A. Guzmøn -- Innovative approaches to develop prophylactic and therapeutic vaccines against HIV/AIDS / Aurelio Cafaro ... [et al.] -- New strategies to overcome the drawbacks of currently available flu vaccines / Epifanio Fichera ... [et al.].
- Pharmaceutical biotechnology. 2nd ed. 2006CRCnetBASE
- Photon-based nanoscience and nanobiotechnology 2006Springer
- Photonics and lasers an introduction 2006WileyPart 1. Propagation of light -- ch. 1. Overview -- ch. 2. Review of optics -- ch. 3. Planar waveguides -- ch. 4. Cylindrical waveguides -- ch. 5. Losses in optical fibers -- ch. 6. Dispersion in optical fibers -- ch. 7. Fiber connections and diagnostics -- ch. 8. Photonic crystal optics -- ch. 9. Nonlinear optics -- Part 2. Generation and Detection of Light -- ch. 10. Review of semiconductor physics -- ch. 11. Light sources -- ch. 12. Light source to waveguide coupling efficiency -- ch. 13. Optical detectors -- ch. 14. Photodiode detectors -- Part 3. Laser light -- ch. 15. Lasers and coherent light -- ch. 16. Optical resonators -- ch. 17. Guassian beam optics -- ch. 18. Stimulated emission and optical gain -- ch. 19. Optical amplifiers -- ch. 20. Laser oscillation -- ch. 21. CW laser characteristics -- ch. 22. Pulsed lasers -- ch. 23. Survey of laser types -- Part 4. Light-based communications -- ch. 24. Optical communications -- Appendix A. Solid angle and the brightness theorem -- Appendix B. Fourier synthesis and the uncertainty relation.
- Measuring endogenous electric fields / Richard Nuccitelli -- Investigation systems to study the biological effects of weak physiological electric fields / Francis X. Hart -- Endogenous bioelectric signals as morphogenetic controls of development, regeneration, and neoplasm / Michael Levin -- Stem cell physiological responses to noninvasive electrical stimulation / Igor Titushkin ... [et al.] -- Electrical signals control corneal epithelial cell physiology and wound repair / Colin D. McCaig -- Physiological electric fields can direct keratinocyte migration and promote healing in chronic wounds / Christine E. Pullar -- Electrical control of angiogenesis / Entong Wang ... [et al.] -- Inflammatory cell electrotaxis / Francis Lin and Christine E. Pullar -- Effects of DC electric fields on migration of cells of the musculoskeletal system / Najmuddin J. Gunja, Clark T. Hung, and J. Chlöe Bulinski -- Neuronal growth cone guidance by physiological DC electric fields / Ann M. Rajnicek -- Can applied voltages be used to produce spinal cord regeneration and recovery in humans? / Richard Ben Borgens -- Bioelectricty of cancer : voltage-gated ion channels and direct-current electric fields / Mustafa B. A. Djamgoz.
- Phytoremediation methods and reviews 2007Springer Protocols
- Plant chromosome engineering 2011Springer ProtocolsRecent advances in plant transformation -- Engineering the plastid genome of nicotiana sylvestris, a diploid model species for plastid genetics -- Homologous recombination in plants : An antireview -- Chromosome painting for plant biotechnology -- Plant B chromosomes -- Telomere truncation in plants -- Engineered plant minichromosomes -- Method for bxb1-mediated site-specific integration in planta -- Targeted mutagenesis in arabidopsis using zinc-finger nucleases -- Vectors and methods for hairpin RNA and artificial microRNA-mediated gene silencing in plants -- Recombinant protein expression in nicotiana -- Chromosome analysis and sorting using flow cytometry -- Super-stretched pachytene chromosomes for plant molecular cytogenetic mapping -- Cytological dissection of the triticeae chromosomes by the gametocidal system -- Development and use of oat-maize chromosome additions and radiation hybrids -- Enhancer trapping in plants -- Chromatin beacons : Global sampling of chromatin physical properties using chromatin charting lines -- Transposable elements as catalysts for chromosome rearrangements.
- Plant tissue culture engineering 2006Springer
- Plant-derived vaccines technologies & applications 2011Future MedPlant-derived vaccines : technologies & applications / Franco M. Buonaguro -- Patents and molecular farming / Pascal M.W. Drake & Harry Thangaraj -- In planta production of recombinant and indigenous adjuvants / Antonio Granell, Asun Fernandez-del-Carmen & Diego Orzáez -- Rapid and high-yield production of immunotherapeutic plant-made antibodies / Cristina Capodicasa, Marcello Donini, Maria Elena Villani & Eugenio Benvenuto -- Vaccine peptide display on recombinant tobacco mosaic virus particles / Tatiana V. Komarova, Igor V. Petrunia & Yuri L. Dorokhov -- Plastid transformation as a tool for plant-based production of vaccines and therapeutic proteins / Paolo Lenzi, Nunzia Scotti, Pal Maliga & Teodoro Cardi -- Prophylactic and therapeutic HPV vaccines from plants / Edward P. Rybicki, Colomba Giorgi & Rosella Franconi -- Plant-derived anti-HIV-1 proteins / Nunzia Scotti, Luigi Buonaguro, Maria Lina Tornesello, Teodoro Cardi & Franco Maria Buonaguro -- Plant-based hepatitis B vaccines / Sergei N. Shchelkunov & Galina A. Shchelkunova -- Influenza vaccines : new perspectives from plants / Chiara Lico, Giampaolo Buriani, Floriana Capuano, Eugenio Benvenuto & Selene Baschieri -- Plant-made mucosal vaccines / Rurick K. Salyaev, Maria Manuela Rigano & Natalya I. Rekoslavskaya -- Current status of plant-made veterinary vaccines / Assunta Pelosi, Claire Penney, Huai-Yian Ling & Amanda M. Walmsley.
- Plant-produced microbial vaccines 2009SpringerPlant vaccines: an immunological perspective / D.C. Hooper -- Display of peptides on the surface of tobacco mosaic virus particles / M.L. Smith ... [et al.] -- Chloroplast-derived vaccine antigens and biopharmaceuticals: expression, folding, assembly and functionality / S. Chebolu and H. Daniell -- Production of antibodies in plants: approaches and perspectives / K. Ko, R. Brodzik and Z. Steplewski -- Plant production of veterinary vaccines and therapeutics / R.W. Hammond and L.G. Nemchinov -- Plant-based oral vaccines: results of human trials / C.O. Tacket.
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A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available. Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences. Includes cited reference searching, citation maps, and an analyze tool.Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not. Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.The National Guideline Clearinghouse (NGC): A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines. Over 10,000 notes outline the status of specific infections within each country.
Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.