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Biotechnology

  • 2006 CRCnetBASE
    Quirke, N.
  • 2012 Springer
    Turksen, Kursad.
  • 2013 Springer
    Pletschke, Brett; Shukla, Pratyoosh.
    Improvement of thermostable enzyme with sugar metabolic activity by targeted mutagenesis -- Glycoside hydrolases for modification of glycosylation in polyphenolic antioxidants -- On the enzyme specificity for the synthesis of prebiotic galacto-oligosaccharides -- Microbial mannanases: properties and applications -- Enzyme Synergy for Enhanced Degradation of Lignocellulosic Waste -- Manganese peroxidase: molecular diversity, heterologous expression and applications -- Advance Techniques in Enzyme Research -- Regulatory motif identification in biological sequences: An overview of computational methodologies -- Structural, Molecular and Functional Aspects of Chitin deacetylase -- Role of enzymes and proteins in plant -- microbe interaction : A study of M. oryzae vs Rice -- Industrial enzyme applications in biorefineries for starchy materials.
  • 2006 Springer
    Spekowius, Gerhard; Wendler, Thomas.
  • 2012 Springer
    Aghdami, Nasser; Baharvand, Hossein.
    Advances in stem cell research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
  • 2013 ebrary
    Herrick, James A.; Hyde, Michael J.
    Faith in science : professional and public discourse on regenerative medicine / Tristan Keys, Nancy M. P. King, and Anthony Atala -- From Arrowsmith to Atwood : how did we come to disrespect science? / Ronald M. Green -- The "warfare" of science and religion and science's ethical profile / Thomas M. Lessl -- Is there a human nature? : an argument against modern excarnation / Jean Bethke Elshtain -- Crossing frontiers of science : trespassing into a godless space, or, Fulfilling our manifest destiny / Leah Ceccarelli -- The angels and devils of representing Prozac / Tod Chambers -- "Leave your medicine outside" : bioethics, spirituality, and the rhetoric of Appalachian serpent handlers / Bill J. Leonard -- Biovaluable stories and a narrative ethics of reconfigurable bodies / Arthur W. Frank -- Blacks and the language of their biotechnological future / Ezra E. H. Griffith -- Bioethics, economism, and the rhetoric of technological innovation / Howard Brody -- Technologies of the self at the end of life : pastoral power and the rhetoric of advance care planning / Lisa Kernen -- Suffering and the rhetoric of care / Judy Segal.
  • 2009 Springer
    Rehm, Bernd.
  • 2015
    Richardson, Liz.
    Recent initiatives have sought to close gaps between the two federal agencies' medical technology evaluation processes.
  • 2008 Springer
    Brody, Baruch A.; Lustig, B. Andrew; McKenny, Gerald P.
  • 2012 Springer Protocols
    Hofreiter, Michael; Shapiro, Beth Alison.
    Setting up an ancient DNA laboratory / Tara L. Fulton -- A phenol-chloroform protocol for extracting DNA from ancient samples / Ross Barnett and Greger Larson -- DNA extraction of ancient animal hard tissue samples via adsorption to silica particles / Nadin Rohland -- Case study : recovery of ancient nuclear DNA from toe pads of the extinct passenger pigeon / Tara L. Fulton, Stephen M. Wagner, and Beth Shapiro -- Extraction of DNA from paleofeces / Melanie Kuch and Hendrik Poinar -- DNA extraction from keratin and chitin / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient sloth DNA recovered from hairs preserved in paleofeces / Andrew A. Clack, Ross D.E. MacPhee, and Hendrik N. Poinar -- Ancient DNA extraction from soils and sediments / James Haile -- DNA extraction from fossil eggshell / Charlotte L. Oskam and Michael Bunce -- Ancient DNA extraction from plants / Logan Kistler -- DNA extraction from formalin-fixed material / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient DNA recovered from Pleistocene-age remains of a Florida armadillo / Brandon Letts and Beth Shapiro -- Nondestructive DNA extraction from museum specimens / Michael Hofreiter -- Case study : using a nondestructive DNA extraction method to generate mtDNA sequences from historical chimpanzee specimens / Elmira Mohandesan, Stefan Prost, and Michael Hofreiter -- PCR amplification, cloning, and sequencing of ancient DNA / Tara L. Fulton and Mathias Stiller -- Quantitative real-time PCR in aDNA research / Michael Bunce, Charlotte L. Oskam, and Morten E. Allentoft -- Multiplex PCR amplification of ancient DNA / Mathias Stiller and Tara L. Fulton -- Preparation of next-generation sequencing libraries from damaged DNA / Adrian W. Briggs and Patricia Heyn -- Generating barcoded libraries for multiplex high-throughput sequencing / Michael Knapp, Mathias Stiller, and Matthias Meyer -- Case study : targeted high-throughput sequencing of mitochondrial genomes from extinct cave bears via direct multiplex PCR sequencing (DMPS) / Mathias Stiller -- Target enrichment via DNA hybridization capture / Susanne Horn -- Case study : enrichment of ancient mitochondrial DNA by hybridization capture / Susanne Horn -- Analysis of high-throughput ancient DNA sequencing data / Martin Kircher -- Phylogenetic analysis of ancient DNA using BEAST / Simon Y.W. Ho.
  • 2013 Springer
    Davis, Paul J.; Mousa, Shaker A.
    This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.
  • 2014 ScienceDirect
    Singh, Anchal; Verma, Ashish S.
    Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field. Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases. Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering.
  • 2007 Springer Protocols
    Pörtner, Ralf.
  • 2006 Springer
    Iijima, S.; Nishijima, Ken-ichi.
  • 2009 Springer
    Ikura, Kōji.
  • 2012 Springer
    Dougherty, Thomas J.; Pucci, Michael J.
  • v. 1-2, 2010. Springer
    v. 2, 2010 Springer
    Dübel, Stefan; Kontermann, Roland.
  • 2011 Springer
    Al-Rubeai, Mohamed.
    Engineered antibodies currently represent over 30 per cent of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the generation, optimization, characterization, production and applications of antibody. It provides the necessary theoretical background and description of methods for the expression of antibody in.
  • 2015 Springer
    Anantharamaiah, G. M.; Goldberg, Dennis Ian.
  • 2011 Springer
    Jain, K. K.
  • 2013 Springer
    Jain, K. K.
    Culling together excerpts from a wide range of writings by Dr. Kewal K. Jain on biotechnology topics as they relate to disorders of the nervous system, Applications of Biotechnology in Neurology covers a variety of applications for those working in life sciences and the pharmaceutical sciences, particularly those developing diagnostics and therapeutics for the nervous system. This detailed volume delves into areas such as neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, various methods of improving systemic administration of drugs for targeted delivery to the nervous system, including the use of nanobiotechnology, biotechnology-based strategies and products for neuroprotection, as well as chapters on neurosurgery and personalized neurology.
  • 2014 Springer
    Jain, K. K.
    Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various -omics technologies and their application in oncology are described as oncogenomics and oncoproteomics. This detailed volume also explores molecular diagnostics, nanobiotechnology, cell and gene therapies, as well as personalized oncology. With approximately one thousand selected references from recent literature on this topic and numerous tables and figures, Applications of Biotechnology in Oncology serves as an ideal reference for oncologists, scientists involved in research on cancer biology, and physicians in various specialties who deal with cancer.
  • 2005 Springer
    Makkar, Harinder P. S.; Viljoen, Gerrit J.
  • 2007 Springer
    Alfermann, A. W.; Johnson, T. S.; Verpoorte, R.
    Biosynthesis of plant natural products and characterization of plant biosynthetic pathways in recombinant microorganisms / Erin K. Marasco, Claudia Schmidt-Dannert -- Plant molecular farming: host systems, technology and products / G.B. Sunil Kumar ... [et al.] -- Plastid pathways: metabolic engineering via the chloroplast genom / Tracey Ruhlman, Henry Daniell -- Metabolic engineering of the alkaloid biosynthesis in plants: functional genomics approaches / Kirsi-Marja Oksman-Caldentey, Suvi T. Häkkinen, Heiko Rischer -- Polyamine biosynthetic pathway: a potential target for enhancing alkaloids production: polyamines in alkaloid production / Esha Bhattacharya, M.V.Rajam -- Metabolic engineering in alkaloid biosynthesis: case studies in tyrosine- and putrescine-derived alkaloids: molecular engineering in alkaloid biosynthesis / Fumihiko Sato, Koji Inai, Takashi Hashimoto -- Application of metabolic engineering to vanillin biosynthetic pathways in Vanilla planifolia / Daphna Havkin-Frenkel, Faith C. Belanger -- Pathway engineering of the plant Vitamin C metabolic network / Argelia Lorence, Craig L. Nessler -- Metabolic engineering of terpenoid biosynthesis in plants / Joost Lücker, Harro J. Bouwmeester, Asaph Aharoni -- Metabolic engineering of seed oil biosynthetic pathways for human health / Howard G. Damude, Anthony J. Kinney -- Metabolic engineering in sugarcane: assisting the transition to a bio-based economy / Robert G. Birch -- Single-chain Fv antibody stimulates biosynthesis of secondary metabolites in plants / Waraporn Putalun, Hiroyuki Tamaka, Yukihiro Shoyama -- Metabolic engineering of sulfur assimilation in plants : molecular and biochemical analysis of serine acetyltransferase and cysteine synthase / Masaaki Noji, Kazuki Saito -- Approaches to quality plant based medicine: significance of chemical profiling / Praveen K. Saxena, Ian B. Cole, Susan J. Murch.
  • 2006 ScienceDirect
    Arora, Dilip K.; Berka, Randy M.; Singh, Gautam B.
    The advances in genomic technologies, such as microarrays and high throughput sequencing, have expanded the realm of possibilities for capturing data and analyzing it using automated computer driven bioinformatics tools. With the completion of the sequencing of genomes of human and several model organisms, a quest for scientific discoveries being fueled by integrative and multidimensional techniques in mathematics and computational sciences. In this volume, leading researchers and experts have provided an overview of significant concepts from biological, mathematical, and computational perspectives. It provides a high level view of fungal genomic data integration and annotation, classification of proteins and identification of vaccine targets, identification of secretome or secreted proteins in fungal genomes, as well as tools for analyzing microarray expression profiles. * Provides a survey of theoretical underpinnings on the technological tools and applications * Discusses the tools utilized for the annotation of fungal genomes and addresses issues related to automated annotation generation in a high throughput biotechnology environment * describing the applications of the concepts and methodologies presented throughout the book.
  • 2010 CRCnetBASE
    Lundblad, Roger L.
    Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules -- Light scattering and biomacromolecular conformation -- Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products -- Near-infrared spectroscopy and macromolecular conformation -- Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules -- Use of Raman spectroscopy to evaluate biopharmaceutical conformation -- The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products -- Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation -- Use of nuclear magnetic resonance for the characterization of biotherapeutic products -- Use of chemical probes for the study of protein conformation -- Use of hydrogen exchange in the study of biopharmaceutical conformation -- Use of chemical modification for the conformational analysis of biopharmaceuticals -- Use of immunology to characterize biopharmaceutical conformation -- Use of limited proteolysis to study the conformation of proteins of biotechnological interest -- Other technologies for the characterization of conformational change in biopharmaceuticals -- Development of an experimental approach for the study of the conformation of a biological therapeutic product.
  • 2008 CRCnetBASE
    Goldman, Gustavo Henrique; Osmani, Stephen A.
  • 2012 Springer
    Amit, M.; Itskovitz-Eldor, Joseph.
  • 2014 Springer
    Fioroni, Marco; Dworeck, Tamara; Rodriguez-Ropero, Francisco.
    β-barrel outer membrane channel proteins (OMP) have great potential as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties without affecting the overall protein structure and stability. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. The β-barrel structure serviceability for the nano-material design will be its chief topic giving a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel to be adapted to a non-biological synthetic (i.e. polymer) environment, rendering it competitive with artificial non-biological nano-pores will be outlined specifically the design of a set of protein nano-channels with tailored geometry (diameter, length), conductance and functionality will be reported as a case study. In order to make this book a valuable source of information for both biotechnologists and other scientists interested in bio-nanotechnology an overview of the different steps involved in the nano-channel protein design and production will be reported. The scientific strategy from concept design, theoretical considerations, genetic engineering and large scale production, to system assembly and biophysical characterization with an overview on technological applications including membrane/polymersome technology, will be described.
    Also available: Print – 2014
  • 2007 Springer
    Huopalahti, Rainer.
  • 2007 Springer
    Chan, Warren C. W.
    Synthetic strategies to size and shape controlled nanocrystals and nanocrystal heterostructures / P. Davide Cozzoli and Liberato Manna -- Current approaches for engineering proteins with diverse biological properties / Isaac T.S. Li, Elizabeth Pham, and Kevin Truong -- Past, present, and future of gold nanoparticles / Travis Jennings and Geoffrey Strouse -- Multi-functional gold nanoparticles for drug delivery / Gang Han, Partha Ghosh, and Vincent M. Rotello -- Quantum dots for cancer molecular imaging / Xiaohu Gao and Shivang R. Dave -- Carbon nanostructures as a new high-performance platform for MR molecular imaging / Keith B. Hartman and Lon J. Wilson -- Magnetic nanoparticle assisted molecular MR imaging / Young-wook Jun, Jung-tak Jang, and Jinwoo Cheon -- Patterning metallic nanoparticles by DNA scaffolds / Rahul Chhabra ... [et al.] -- Liposomes in biology and medicine / Reto A. Schwendener -- Fluorescent nanoparticle for bacteria and DNA detection / Wenjun Zhao, Lin Wang, and Weihong Tan -- Dendrimer 101 / Lajos P. Balogh -- Quantum dots and other fluorescent nanoparticles: quo vadis in the cell? / Dusica Maysinger and Jasmina Lovri -- Toxicity studies of fullerenes and derivatives / Jelena Kolosnjaj, Henri Szwarc, and Fathi Moussa -- Toxicity studies of carbon nanotubes / Jelena Kolosnjaj, Henri Szwarc, and Fathi Moussa.
    Also available: Print – 2007
  • 2015 Springer
    Demeule, Barthélemy; Rosenberg, Amy.
  • 2007 CRCnetBASE
    Patel, Ramesh N.
    ch. 1. Nitrilases and nitrile hydratases / Robert DiCosimo -- ch. 2. Biocatalytic deracemization : dynamic resolution, stereoinversion, enantioconvergent processes, and cyclic deracemization / Yolanda Simeo, Wolfgang Kroutil, and Kurt Faber -- ch. 3. A decade of biocatalysis at Glaxo Wellcome / Mahmoud Mahmoudian -- ch. 4. Biocatalysis for synthesis for chiral pharamaceutical intermediates / Ramesh N. Patel -- ch. 5. Directed evolution of lipases and esterases for organic synthesis / Aurelio Hidalgo and Uwe T. Bornscheuer -- ch. 6. Flavin-containing oxidative biocatalysts / Marco W. Fraaije and Willem J.H. van Berkel -- ch. 7. Preparation of chiral pharmaceuticals through enzymatic acylation of alcohols and amines / Vicente Gotor-Fernandez, Francisca Rebolledo, and Vicente Gotor -- ch. 8. Dynamic kinetic resolution and asymmetric transformations by enzyme-metal combinations / Mahn-Joo Kim, Yangsoo Ahn, and Jaiwook Park -- ch. 9. Biotransformation of natural or synthetic compounds for the generation of molecular diversity / Robert Azerad -- ch. 10. Applications of aromatic hydrocarbon dioxygenases / Rebecca E. Parales and Sol M. Resnick -- ch. 11. A genomic approach to investigating baker's yeast reductions / Jon D. Stewart -- ch. 12. Immobilization of enzymes as cross-linked enzyme aggregates : a simple method for improving performance / Roger A. Sheldon -- ch. 13. Biotechnological applications of aldolases / Wolf-Dieter Fessner and Stefan Jennewein -- ch. 14. Enzymatic synthesis of modified nucleosides / Luis A. Condezo ... [et al.] -- ch. 15. Biocatalytic reduction of carbozylic acids : mechanism and applications / Padmesh Venkitasubramanian, Lacy Daniels, and John P.N. Rosazza -- ch. 16. Dehalogenases in biodegradation and biocatalysis / Dick B. Janssen -- ch. 17. Enzymatic synthesis of sugar esters and oligosaccharides from renewable resources / A. Ballestros ... [et al.] -- ch. 18. Efficient methods and instrumentation for engineering custom enzymes / Steven J. Robles, William J. Coleman, and Mary M. Yang -- ch. 19. Deaminating enzymes of the purine cycle as biocatalysts for chemoezymatic synthesis and transformation of antiviral agents structurally related to purine nucleosides / Enzo Santaniello, Pierangela Ciuffreda, and Laura Alessandrini -- ch. 20. Mircobial and enzymatic processes for the production of chiral compounds / Kohsuke Honda ... [et al.] -- ch. 21. Discovery of arylmalonate decarbozylase and conversion of the function by rational design / Kenji Miyamoto and Hiromichi Ohta -- ch. 22. Chemoenzymatic preparation of enantiopure building blocks of synthetic utility / Kenji Mori -- ch. 23. Stereoselective modifications of polyhydorxylated steroids / Elena Fossati and Sergio Riva -- ch. 24. Recent developments in enzymatic acyloin condensations / Owen Ward and Ajay Singh -- ch. 25. Synthesis of chiral alcohols with carbonyl reductase library and robust NAD(P)H regenerating system / Hiroaki Yamamoto and Akinobu Matsuyama -- ch. 26. Comparative analysis of chemical and biocatalyic syntheses of drug intermediates / Michael J. Homann ... [et al.] -- ch. 27. Industrial processes using lyases fo C-C, C-N, and C-O bond formation / Martina Pohl an Andreas Lieses -- ch. 28. State of the art and applications in stereoselective synthesis of chiral cyanohydrins / Franz Effenberger, Siegfried Forster, and Christoph Kobler -- ch. 29. Chiral switches : problems, strategies, opportunities, and experiences / Rene Csuk -- ch. 30. Enzyme evolution for chemical process applications / Gjalt W. Huisman and James J. Lalonde -- ch. 31. Biocatalytic routes to nonracemic chiral amines / Nicholas J. Turner and Reuban Carr -- ch. 32. Enantioselective biocatalytic reduction of ketones for the synthesis of optically active alcohols / Stefan Buchholz and Harald Groger -- ch. 33. Enyzmes catalysis in nonaqueous media : past, present and future / Susanne Dreyer ... [et al.] -- ch. 34. Biocatalyic concepts for the synthesis of optically active amines / Stefan Buchholz and Harald Groger.
  • 2002 CRCnetBASE
    Vijayalakshmi, M. A.
    Upstream and downstream steps in biochromatography / Mookambeswaran A. Vijayalakshmi -- Gel filtration / Kjell-Ove Eriksson -- Ion exchange interaction biochromatography / E. Boschetti and P. Girot -- Hydrophobic (interaction) chromatography of proteins / Herbert P. Jennissen -- Conformational behaviour of polypeptides and proteins in reversed phase and lipophilic environments / Milton W. Hearn -- Affinity chromatography / Jaroslava Turková -- Dye ligand affinity chromatography / Robert K. Scopes -- Immobilized synthetic dyes in affinity chromatography / Nikos E. Labrou and Yannis D. Clonis -- Immobilized histidine ligand affinity chromatography / Oliver Pitiot and Mookambeswaran A. Vijayalakshmi -- Immobilized metal-ion affinity chromatography: from phenomenological hallmarks to structure-based molecular insights / Nadir T. Mrabet and Mookambeswaran A. Vijayalakshmi -- Thiophilic interaction chromatography / Sven Oscarsson and Francisco Batista Viera -- Miscellaneous methods in affinity chromatography: Part 1: Boronic acids as selective ligands for affinity chromatography / Xio-Chuan Liu and William H. Scouten -- Miscellaneous methods in affinity chromatography: Part 2: Shielded affinity chromatography in packed bed and expanded bed mode / Igor Yu. Galaev and Bo Mattiasson -- Glycobiology and biochromatography / Henri Debray, Gérard Strecker and Jean Montreuil -- Capillary electrokinetic chromatography / Gargi Choudhary and Csaba Horváth -- Imprinted polymers as tailor-made stationary phases for affinity separation / Karsten Haupt, Peter A.G. Cormack and Klaus Mosbach -- Computer-aided simulation of biochromatography / Nicolas Voute -- Industrial biochromatography: engineering aspects / F.A.P. Garcia, D.M.F. Prazeres and J.M.S. Cabral -- Validation aspects in biochromatography / Charles Lutsch -- Biochromatography and biomedical applications / C. Legallais, Mookambeswaran A. Vijayalakshmi and Ph. Moriniére.
  • 2015
    Yock, Paul G.
    PrintStatus: Not Checked OutLane Catalog Record
    "This step-by-step guide to medical technology innovation, now in full color, has been rewritten to reflect recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads students, researchers, and entrepreneurs through a proven process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. A wealth of additional material supports the book, including a collection of nearly 100 videos created for the second edition, active links to external websites, supplementary appendices, and timely updates on the companion website at ebiodesign.org. Readers can access this material quickly, easily, and at the most relevant point in the text from within the ebook"--Provided by publisher.
  • 2002 Wiley
    Baggott la Velle, Linda; Bryant, J. A.; Searle, John.
    Introduction to ethics and bioethics / Michael J. Reiss -- The public evaluation of science and technology / Barry Barnes -- Introduction to environmental ethics / Christopher Southgate -- The use of the rainforest as a test case in environmental ethics / Christopher Southgate -- Environmental ethics : further case-studies / Christopher Southgate and Alex Aylward -- Human use of non-human animals : a biologist's view / David de Pomerai -- Human use of non-human animals : a philosopher's perspective / R.G. Frey -- GM crops and food : a scientific perspective / Steve Hughes and John Bryant -- Questioning GM foods / Sue Mayer -- The patenting of genes for agricultural biotechnology / Steve Hughes -- Crop biotechnology and developing countries / Geeta Bharathan ... [et al.] -- Starting human life : the new reproductive technologies / Linda Baggott la Velle -- Genetic information : use and abuse / Bartha Maria Knoppers -- Human genetics and genetic enhancement / Peter Turnpenny and John Bryant -- Patenting human genes : ethical and policy issues / Audrey R. Chapman -- Cloning of animals and humans / Harry Griffin -- Dealing with death : euthanasia and related issues / John Searle -- Animal experimentation in biomedical research / Linda Baggott la Velle.
  • 2010 Springer
    Berra, Bruno; Giardi, Maria Teresa; Rea, Giuseppina.
    The Nutra-Snacks project : basic research and biotechnological programs on nutraceutics / Giuseppina Rea ... [et al.] -- Overview of diet-gene interactions and the example of xanthophylls / Barbara Demmig-Adams and William W. Adams III -- Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders / Giovanni Scapagnini, Calogero Caruso, and Vittorio Calabrese -- Plant phenolics in the prevention and treatment of cancer / Klaus W.J. Wahle ... [et al.] -- Endogenous antioxidants and radical scavengers / Angela Maria Rizzo ... [et al.] -- A nutritional strategy for reducing disease and obesity risks / Teresa Lavecchia ... [et al.] -- Dietary phytochemicals and human health / Justyna Krzyzanowska, Anna Czubacka, and Wieslaw Oleszek -- Bioactive compounds from northern plants / Anja Hohtola -- Nutraceutical use of garlic sulfur-containing compounds / Eleftherios Touloupakis and Demetrios F. Ghanotakis -- Genetic engineering to enhance crop-based phytonutrients (nutraceuticals) to alleviate diet-related diseases / Autar K. Mattoo ... [et al.] -- Perspective for the use of genetic transformants in order to enhance the synthesis of the desired metabolites : engineering chloroplasts of microalgae for the production of bioactive compounds / Udo Johanningmeier and Dirk Fischer -- Biological elicitors of plant secondary metabolites : mode of action and use in the production of nutraceutics / Simone Ferrari -- Hairy root cultures for secondary metabolites production / Laura Pistelli ... [et al.] -- Plant tissue culture : an opportunity for the production of nutraceuticals / Mariella Lucchesini and Anna Mensuali-Sodi -- Plant cell cultures : bioreactors for industrial production / Barbara Ruffoni ... [et al.] -- Determination of the antioxidants' ability to scavenge free radicals using biosensors / Montserrat Cortina-Puig ... [et al.] -- Biosensors for the determination of phenolic metabolites / Simona Carmen Litescu, Sandra Eremia, and Gabriel Lucian Radu -- Methods for the determination of antioxidant capacity in food and raw materials / Simona Carmen Litescu, Sandra Eremia, and Gabriel Lucian Radu -- Analytical methods for the extraction and identification of secondary metabolite production in 'in vitro' plant cell cultures / Alessandra Bertoli ... [et al.] -- Biosensors for functional food safety and analysis / Teresa Lavecchia, Arianna Tibuzzi, and Maria Teresa Giardi -- Biosensors for secondary metabolites, two case studies : ochratoxin A and microcystin / Monica Campàs, Beatriz Prieto-Simón And Régis Rouillon -- Biosensors as analytical tools in food fermentation industry / Lise Barthelmebs ... [et al.] -- An overview of the functional food market : from marketing issues and commercial players to future demand from life in space / Francesca Vergari, Arianna Tibuzzi, and Giovanni Basile -- Legislation on nutraceuticals and food supplements a comparison between regulations in USA and EU / Roberto Giunta, Giovanni Basile, and Arianna Tibuzzi.
    Also available: Print – 2010
  • 2005 ScienceDirect
    Finegold, David.
    Introduction -- Merck: Staying the course -- Genzyme: Putting patients first -- Millennium Pharmaceuticals, Inc.: Creating and sustaining corporate values -- Maxim Pharmaceuticals (A): Internal and external dialogues -- Diversa Inc.: Ethical issues in bioprospecting partnerships -- Pipeline Biotech A/S: Competing regulatory regimes for laboratory animal experiments -- TGN Biotech: A start-up with ethical roots -- Interleukin Genetics and Alticor: An unlikely partnership -- Sciona Ltd.: A pioneer in nutrigenomics: The path to consumer acceptance -- Affymetrix, Inc.: Using corporate ethics advice -- PharmaSNPs Inc.: Creating an ethics advisory board -- Monsanto Company: Bio-agriculture pioneer -- Novo Nordisk: The triple bottom line -- Conclusion: Lessons for companies and future issues.
  • 2013
    Contreras, Jorge L.; Cuticchia, A. Jamie.
    "The book begins with an overview of the evolving bioinformatics field then explores legal issues surrounding the software tools that enable large-scale computational biology, including procurement and licensing of commercial software systems, in-house and contracted software development and issues surrounding open source software. Legal issues associated with software tools for large-scale computational biology are examined, including procurement and licensing of commercial software systems, in-house and contracted software development, and open source software." -- [Publisher-supplied data]
  • 2005 MyiLibrary
    Chen, Yi-Ping Phoebe.
  • 2014 Cambridge
    2014 Knovel
    Ma, Peter X.
    "Written by world-leading experts, this book focusses on the role of biomaterials in stem cell research and regenerative medicine. Emphasising basic principles and methodology, it covers stem cell interactions, fabrication technologies, design principles, physical characterisation and biological evaluation, across a broad variety of systems and biomaterials. Topics include: stem cell biology, including embryonic stem cells, IPS, HSC and progenitor cells; modern scaffold structures, including biopolymer, bioceramic, micro- and nanofiber, ECM and biohydrogel; advanced fabrication technologies, including computer-aided tissue engineering and organ printing; cutting-edge drug delivery systems and gene therapy techniques; medical applications spanning hard and soft tissues, the cardiovascular system and organ regeneration. With a contribution by Nobel laureate Shinya Yamanaka, this is a must-have reference for anyone in the field of biomaterials, stem cell biology and engineering, tissue engineering and regenerative medicine"--Provided by publisher.
  • 2012 Springer
    Suzuki, Shuko; Ikada, Yoshito.
    1. Introduction -- 2. Biological Events Associated with Surgical Operation -- 3. Bioabsorbable Polymers -- 4. Sealants (Adhesives) to Prevent Bleeding -- 5. Barriers to Prevent Tissue Adhesion -- 6. Devices for Bone Fixation -- 7. Growth Factors for Promoting Wound Healing -- 8. Sutures for Wound Closure -- 9. Conclusions.
  • 2012 ebrary
    Klees, Edward; Horvitz, H. Robert.
    Issues to consider when negotiating a consulting agreement -- What constitutes consulting? -- Scope of services -- Cash compensation -- Shares, stock options, and taxes -- Confidentiality obligations -- IP rights -- Noncompetition -- Time commitment -- Term and termination -- Multiple relationships with one company -- Start-up issues -- Other clauses -- Use of consulting entity.
  • 2014 Cambridge
    Farag, Aly A.
    Overview of biomedical image analysis -- Overview of two-dimensional signals and systems -- Biomedical imaging modalities -- Random variables -- Random processes -- Basics of random fields -- Probability density estimation by linear models -- Basics of topology and computational geometry -- Geometric features extraction -- Variational approaches and level sets -- Segmentation -- statistical approach -- Segmentation -- variational approach -- Basics of registration -- Variational methods for shape registrations -- Statistical models of shape and appearance.
  • 2005 CRCnetBASE
    Malsch, Neelina H.
    Converging technologies : nanotechnology and biomedicine / Mihail C. Roco -- Trends in biomedical nanotechnology programs worldwide / Mark Morrison and Ineke Malsch -- Nanotechnology and trends in drug delivery systems with self-assembled carriers / Kenji Yamamoto -- Implants and prostheses / Jeroen J.J.P. van den Beucken, X. Frank Walboomers, and John A. Jansen -- Diagnostics and high throughput screening / Aránzazu del Campo and Ian J. Bruce -- Nano-enabled components and systems for biodefense / Calvin Shipbaugh ... [et al.] -- Social and economic contexts : making choices in the development of biomedical nanotechnology / Ineke Malsch -- Potential risks and remedies / Emmanuelle Schuler.
    Also available: Print – 2005
  • 2010 Atypon
    Weinfurt, Phillip T.
    Evaluating biomedical technology poses a significant challenge in light of the complexity and rate of introduction in today's healthcare delivery system. Successful evaluation requires an integration of clinical medicine, science, finance, and market analysis. Little guidance, however, exists for those who must conduct comprehensive technology evaluations. The 3Q Method meets these present day needs. The 3Q Method is organized around 3 key questions dealing with 1) clinical and scientific basis, 2) financial fit and 3) strategic and expertise fit. Both healthcare providers (e.g., hospitals) and medical industry providers can use the Method to evaluate medical devices, information systems and work processes from their own perspectives. The book describes the 3Q Method in detail and provides additional suggestions for optimal presentation and report preparation.
  • 2010
    Clarke, Adele.
    Biomedicalization : technoscientific transformations of health, illness, and U.S biomedicine / Adele E. Clarke, Janet K. Shim, Laura Mamo, Jennifer Ruth Fosket, and Jennifer R. Fishman -- Charting (bio)medicine and (bio)medicalization in the United States, 1890/present / Adele E. Clarke, Jennifer Ruth Fosket, Laura Mamo, Jennifer R. Fishman, and Janet K. Shim -- From the rise of medicine to biomedicalization : U.S. healthscapes and iconography, circa 1890/present / Adele E. Clarke -- Gender and medicalization and biomedicalization theories / Elianne Riska -- Fertility, Inc. : consumption and subjectification in U.S. lesbian reproductive practices / Laura Mamo -- The body as image : an examination of the economic and political dynamics of magnetic resonance imaging and the construction of difference / Kelly Joyce -- The stratified biomedicalization of heart disease : expert and lay perspectives on racial and class inequality / Janet K. Shim -- Marking populations and persons at risk : molecular epidemiology and environmental health / Sara Shostak -- Surrogate markers and surrogate marketing in biomedicine : the regulatory etiology and commercial progression of "ethnic" drug development / Jonathan Kahn -- The making of Viagra : the biomedicalization of sexual dysfunction / Jennifer R. Fishman -- Bypassing blame : bariatric surgery and the case of biomedical failure / Natalie Boero -- Breast cancer risk as disease : biomedicalizing risk / Jennifer Ruth Fosket -- Biopsychiatry and the informatics of diagnosis : governing mentalities / Jackie Orr.
  • 2006 CRCnetBASE
    Bar-Cohen, Yoseph.
  • 2007
    Liu, Jian-Qin; Shimohara, Katsunori.
  • 2009 CRCnetBASE
    Reisner, David Evans.
  • 2006 Springer
    Lewis, Randolph V.; Renugopalakrishnan, Vencatesan.
  • 2007
    Papazoglou, Elisabeth S.; Parthasarathy, Aravind.
  • 2013 CRCnetBASE
    Patel, Vinood B.; Preedy, Victor R.
    Functional optical imaging-based biosensors / Pablo Iglesias and Jose A. Costoya -- Use of a surface plasmon resonance (SPR) biosensor to characterize zwitterionic coatings on SiO2 for cancer biomarker detection / Norman D. Brault, Shaoyi Jiang, and Qiuming Yu -- Microcantilever-based biosensor array for tumor angiogenic marker detection / Riccardo Castagna and Carlo Ricciardi -- Electrochemical DNA biosensors at the nanoscale / Rosa Letizia Zaffino ... [et al.] -- Aptamer-based biosensors for cancer studies / Ilaria Palchetti and Marco Mascini -- Fluorescent biosensors for cancer cell imaging and diagnostics / May C. Morris -- Electrical and electrochemical immunosensor for cancer study / Seung Yong Lee and Seung Yong Hwang -- Multifunctional nanobiosensors for cancer / Dai-Wen Pang and Er-Qun Song -- Silicon nanowire biosensor for cancer markers / Yang-Kyu Choi and Chang-Hoon Kim -- DNA-electrochemical biosensors and oxidative damage to DNA : application to cancer / Victor Constantin Diculescu and Ana Maria Oliveira Brett -- Asparaginase-based asparagine biosensors and their application to leukemia / Neelam Verma and Kuldeep Kumar -- Breast cancer detection using surface plasmon resonance-based biosensors / Chii-Wann Lin and Chia-Chen Chang -- Detection of miRNA with silicon nanowire biosensors / Guo-Jun Zhang -- Biosensors for BCR-ABL activity and their application to cancer / Yusuke Ohba ... [et al.] -- Optical fiber nanobiosensor for single living cell detections of cancers / Xin Ting Zheng and Chang Ming Li -- Microfluidic biosensors for thyroglobulin detection and application to thyroid cancer / Seokheun Choi and Junseok Chae -- Optical biosensors and applications to drug discovery and development in cancer research / Carlo Bertucci and Angela De Simone -- Single-chain fragment variable recombinant antibodies and their applications in biosensors for cancer diagnosis / Xiangqun Zeng and Ray Mernaugh -- DNA biosensor for rapid detection of anticancer drugs / Sigen Wang and Ruili Wang -- Using UV light to engineer biosensors for cancer detection : the case of prostate specific antigen / Maria Teresa Neves-Petersen, Antonietta Parracino, and Steffen B. Petersen.
  • 2010 Springer
    Sen, Ramkrishna.
    Also available: Print – 2010
  • 2006 Springer
    Giardi, Maria Teresa; Piletska, Elena V.
    Introduction: the emergence of a new technology / Maria Teresa Giardi -- A brief story of biosensor technology / Marco Mascini -- Photosystem II: composition and structure / Aspasia Spyridaki, Emmanuel Psylinakis, and Demetrios F. Ghanotakis -- Biogenesis and structural dynamics of the photosystem II complex / Josef Komenda ... [et al.] -- Engineering the D1 subunit of photosystem II: application to biosensor technology / Udo Johanningmeier ... [et al.] -- Chloroplast genomics of land plants and algae / Margarita S. Odintsova and Nadezhda P. Yurina -- Comparison of the immobilization techniques for photosystem II / Regis Rouillon ... [et al.] -- Comparison of photosynthetic organisms of the evolution scale for protein biochips / Maria Teresa Giardi, Dania Esposito, and Giuseppe Torzillo -- Signal transduction techniques for photosynthetic proteins / Pinalysa Cosma, Francesco Longobardi, and Angela Agostiano -- Biotechnological and computational approaches for the development of biosensors / Giulio Testone ... [et al.] -- The problem of herbicide water monitoring in Europe / Licia Guzzella and Fiorenzo Pozzoni -- Application of chloroplast D1 protein in biosensors for monitoring photosystem II-inhibiting herbicides / Elena V. Piletska, Sergey A. Piletsky, and Regis Rouillon -- Photosystem II-based biosensors for the detection of photosynthetic herbicides / Maria Teresa Giardi and Emanuela Pace -- Mimicking the plastoquinone-binding pocket of photosystem II using molecularly imprinted polymers / Florent Breton ... [et al.] -- Photosystem II biosensors for heavy metals monitoring / Regis Rouillon ... [et al.] -- Development of biosensors for the detection of hydrogen peroxide / Louisa Giannoudi, Elena V. Piletska, and Sergey A. Piletsky -- Biodevices for space research / Dania Esposito ... [et al.] -- Successes in the development and application of innovative techniques / Eleftherios touloupakis ... [et al.].
  • v. 27-, 2003- CRCnetBase
    v. 29, 2005 CRCnetBase
  • v. 4-, 2006- Springer
  • 2014 CRCnetBASE
    Khan, Firdos Alam.
    "This book is a comprehensive overview of all the important aspects of medical biotechnology intended for interested, scientifically oriented laypersons, along, who want a relatively low level presentation of important biotechnology medical specialties such as bacteriology, immunology, recombinant DNA, molecular diagnostics, gene therapy, synthetic biology, tissue engineering, bioethics, IP issues, vaccines, and more"-- Provided by publisher.
  • 2011 Springer
    Barbarisi, Alfonso.
  • 2002 ScienceDirect
    Lantto, R.; Viikari, Liisa.
  • 2012 CRCnetBASE
    Ayyachamy, Manimaran; Gupta, Vijai Kumar.
    Identification of fungal pathogenicity genes by Agrobacterium tumefaciens-mediated transformation / Karunakaran Maruthachalam ... [et al.] -- The genetics and molecular biology of carotenoid biosynthesis in mucorales / Catalina Sanz, Mahdi Shahriari, and Arturo P. Eslava -- Induction and repression of carbohydrate degrading enzymes in fungi with special reference to their coding genes / Pauline Walsh, Alan Hernon, and Anthonia O'Donovan -- Involvement of ADH1, IPT1, and PMT genes in Candida albicans pathogenesis / Mahmoud Rouabhia and Mahmoud Ghannoum -- Enhanced resistance to fungal pathogens in plants through selective utilization of useful fungal genes / B.K. Sarma ... [et al.] -- Genes encoding penicillin and cephalosporin biosinthesis in Acremonium chrysogenum : two separate clusters are required for cephalosporin production / Juan-Francisco Martøn, Carlos Garcia-Estrada, and Ricardo V. Ullon -- A review of the fungal B-galactosidase gene and its biotechnological applications / Anne G. Lydon -- Trichoderma genes involved in interactions with fungi and plants / Mala Mukherjee -- Use of luciferases as a tool to analyze fungal physiology in association with gene transcription / David M. Arana and Jess Pla -- Fungal genes and their respective enzymes in industrial food, bio-based, and pharma applications / Marco van den Berg ... [et al.] -- Fungal metacaspases : an overview / Anthonia O'Donovan, Finola E. Cliffe, and Mary C. Shier -- Signaling molecules in the Arbuscular mycorrhizal fungi / Mohammad Miransari -- Role of pathogenic genes of Fusarium oxysporum, coding cell wall degrading enzymes during wilt infection in plants / Vijai Kumar Gupta, Maria Tuohy, and A. Manimaran -- Engineering fungal expression systems : recombinant expression of two class I alpha-1, 2-mannosidases from the filamentous fungus Aspergillus nidulans / C. Joshua Eades and William E. Hintz -- PCR-diagnostic of Septoria nodorum berk : aggresivenes in wheat tissue / I.V. Maksimov and A.Sh. Valeev -- Detection of toxigeneic and pathogenic fungi targeting metabolic pathway genes / Venkataramana Mudili ... [et al.] -- Pathogenicity genes in entomopathogenic fungia used as biopesticides / K. Uma Devi ... [et al.].
  • 2013 CRCnetBASE
    Lundblad, Roger L.
    "Discussing the role of plasma proteins in current biotechnology, this book describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, and mass spectrometry as well as updates not published since 1975"--Provided by publisher.
  • 2002 ScienceDirect
    Norus, Jesper.
  • 2002 ScienceDirect
    Singh, Vedpal; Stapleton, Raymond D.
  • 2006 Springer
    Bonnick, Sydney Lou; Lewis, Lori Ann.
  • 2013 Springer
    Bonnick, Sydney Lou; Lewis, Lori Ann.
    An introduction to conventions in densitometry -- Densitometry techniques -- Skeletal anatomy in densitometry -- Performing a DXA PA lumbar spine, proximal femur, or forearm DXA study -- Radiation safety in x-ray densitometry -- Quality control procedures -- The importance of precision -- Using absolute risk to predict fracture risk in clinical practice -- An overview of osteoporosis -- Interpretation of bone densitometry data -- Less than perfect scan images -- Pediatric densitometry -- VFA imaging, femoral morphometry, and hip structural analysis -- Body composition analysis.
  • 2013 ebrary
    Bradley, James T.
    A guide to the rapidly progressing Age of Biotechnology, Brutes or Angels provides basic information on a wide array of new technologies in the life sciences, along with the ethical issues raised by each. With stem cell research, Dolly the cloned sheep, in vitro fertilization, age retardation, and pharmaceutical mind enhancement, humankind is now faced with decisions that it has never before had to consider. The thoughtfulness, or lack of it, that we bring to those decisions will largely determine the future character of the living world.
  • 2005 NCBI Bookshelf
    Sayers, Eric; Wheeler, D. L.
  • 2010 ScienceDirect
    Stephenson, Frank Harold.
    Chapter 1. Scientific notation and metric prefixes -- Chapter 2. Solutions, mixtures, and media -- Chapter 3. Cell growth -- Chapter 4. Working with bacteriophages -- Chapter 5. Nucleic acid quantification -- Chapter 6. Labeling nucleic acids with radioisotopes -- Chapter 7. Oligonucleotide synthesis -- Chapter 8. The polymerase chain reaction (PCR) -- Chapter 9. The real-time polymerase chain reaction (RT-PCR) -- Chapter 10. Recombinant DNA -- Chapter 11. Protein -- Chapter 12. Centrifugation -- Chapter 13. Forensics and paternity.
  • 2008
    Freedman, Toby.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2015 Springer Protocols
    Doran, Pauline M.
    Cartilage tissue engineering : what have we learned in practice / Pauline M. Doran -- Human fetal and adult chondrocytes / Kifah Shahin, Nastaran Mahmoudifar, and Pauline M. Doran -- Mesenchymal stem cells derived from human bone marrow / Oliver F. W. Gardner, Mauro Alini, and Martin J. Stoddart -- Mesenchymal stem cells derived from human adipose tissue / Nastaran Mahmoudifar and Pauline M. Doran -- Derivation and chondrogenic commitment of human embryonic stem cell-derived mesenchymal progenitors / Hicham Drissi ... [et al.] -- Differentiation of human induced pluripotent stem cells to chondrocytes / Rosa M. Guzzo and Hicham Drissi -- Gene transfer and gene silencing in stem cells to promote chondrogenesis / Feng Zhang and Dong-An Wang -- Hydrogels with tunable properties / Peggy P.Y. Chan -- Decellularized extracellular matrix scaffolds for cartilage regeneration / Shraddha Thakkar, Hugo Fernandes, and Lorenzo Moroni -- Use of interim scaffolding and neotissue development to produce a scaffold-free living hyaline cartilage graft / Ting Ting Lau ... [et al.] -- Bioprinted scaffolds for cartilage tissue engineering / Hyun-Wook Kang, James J. Yoo, and Anthony Atala -- Scaffolds for controlled release of cartilage growth factors / Marie Morille ... [et al.] -- Nanostructured capsules for cartilage tissue engineering / Clara R. Correia, Rui L. Reis, and João F. Mano -- Stratified scaffolds for osteochondral tissue engineering / Patcharakamon Nooeaid, Gundula Schulze-Tanzil, and Aldo R. Boccaccini -- Mechanobioreactors for cartilage tissue engineering / Joanna F. Weber, Roman Perez, and Stephen D. Waldman -- Shear and compression bioreactor for cartilage synthesis / Kifah Shahin and Pauline M. Doran -- Microbioreactors for cartilage tissue engineering / Yu-Han Chang and Min-Hsien Wu -- Transplantation of tissue-engineered cartilage in an animal model (xenograft and autograft) : construct validation / Hitoshi Nemoto, Deborah Watson, and Koichi Masuda -- Proteomic analysis of engineered cartilage / Xinzhu Pu and Julia Thom Oxford -- Mechanical testing of cartilage constructs / Dinorath Olvera, Andrew Daly, and Daniel John Kelly.
  • 2005 CRCnetBASE
    Hu, Wei-Shou; Ozturk, Sadettin S.
  • 2009 Springer
    Gee, Adrian P.
    Part 1. Regulatory. -- Regulation of Cell Product Manufacturing and Delivery: A United States Perspective / R.W. Lindblad -- The Regulatory Situation for Academic Cell Therapy Facilities in Europe / I. Slaper-Cortenbach, M. Scott, D. Herrmann, M. Introna and K. Theunissen, et al. -- A Regulatory System for Cell and Tissue Therapies: Proposed Approach in Australia / A. Farrugia -- Part 2. GMP Facility Design. -- University of Minnesota - Molecular and Cellular Therapeutics (MCT) / D.H. McKenna -- University of Pittsburgh Cancer Institute - Hematopoietic Stem Cell Laboratory (HSC Lab)/Immunological Monitoring and Cellular Products Laboratory (IMCPL) / D.L. Griffin, A.D. Donnenberg and T.L. Whiteside / Baylor College of Medicine - Center for Cell and Gene Therapy (CAGT) / A. Gee -- Design of a New GMP Facility - Lessons Learned / A. Gee -- Part 3. Professional Cell Therapy Standards. -- AABB Cell Therapy Standards / Z.M. Szczepiorkowski and E. Nunes -- Professional Standards for Cellular Therapies: Foundation for the Accreditation of Cellular Therapy (FACT) / P.I. Warkentin -- Part 4. Facility Operations -- Standard Operating Procedures / C.G. Lindgren -- Staffing, Training, and Competency / D.M. Kadidlo -- Cleaning Procedures / A. Gee and D.L. Lyon -- Environmental Monitoring / A. Gee and D.L. Lyon -- Supply Management / A. Gee and C.M. Rooney -- Facility Equipment / D.L. Griffin -- Quality / J.W. Atkins -- Product Manufacturing / A. Gee -- Product Review, Release, and Administration / N.H. Collins -- Use of a Facility Master File to Facilitate Regulatory Submissions for Cell Therapy Products / E.J. Read and H.M. Khuu.
  • 2013 Springer Protocols
    Elbayoumi, Tamer; Olsen, Mark; Weissig, Volkmar.
    Nanoparticle-GFP "chemical nose" sensor for cancer cell identification / Daniel F. Moyano and Vincent M. Rotello -- Method to map spatiotemporal pH changes in a multicellular living organism using a DNA nanosensor / Sunaina Surana and Yamuna Krishnan -- Simple method to visualize and assess the integrity of lysosomal membrane in mammalian cells using a fluorescent dye / Syed K. Sohaebuddin and Liping Tang -- Gold nanoparticle as a marker for precise localization of nano-objects within intracellular sub-domains / Valeriy Lukyanenko and Vadim Salnikov -- Immunoisolation of nanoparticles containing endocytic vesicles for drug quantitation / Ari Nowacek [and others] -- Methods for isolation and identification of nanoparticle-containing subcellular compartments / Ari Nowacek [and others] -- Permeabilization of cell membrane for delivery of nano-objects to cellular sub-domains / Valeriy Lukyanenko -- Method to encapsulate molecular cargo within DNA Icosahedra / Dhiraj Bhatia [and others] -- Delivery of plasmid DNA to mammalian cells using polymer-gold nanorod assemblies / James Ramos, Huang-Chiao Huang, and Kaushal Rege -- Lipophilic-formulated gold porphyrin nanoparticles for chemotherapy / Puiyan Lee and Kenneth K.Y. Wong -- Mitochondria-specific nano-emulsified therapy for myocardial protection against doxorubicin-induced cardiotoxicity / Amy Faulk, Volkmar Weissig, and Tamer Elbayoumi -- Formation of pit-spanning phospholipid bilayers on nanostructured silicon dioxide surfaces for studying biological membrane events / Indriati Pfeiffer and Michael Zach -- Characterization of nanoparticle-lipid membrane interactions using QCM-D / Rickard Frost and Sofia Svedhem -- Single-cell nanosurgery / Maxwell B. Zeigler and Daniel T. Chiu -- Single quantum dot imaging in living cells / Jerry C. Chang and Sandra J. Rosenthal -- Fabrication of fluorescent silica nanoparticles with aggregation-induced emission luminogens for cell imaging / Sijie Chen, Jacky W.Y. Lam, and Ben Zhong Tang -- Monitoring the degradation of reduction-sensitive gene carriers with fluorescence spectroscopy and flow cytometry / Constantin Hozsa, Miriam Breunig, and Achim Gopferich -- Quantification of intracellular mitochondrial displacements in response to nanomechanical forces displacements in response to nanomechanical forces / Yaron R. Silberberg and Andrew E. Pelling -- Imaging select mammalian organelles using fluorescent microscopy : application to drug delivery / Paul D.R. Dyer [and others] -- Real-time particle tracking for studying intracellular trafficking of pharmaceutical nanocarriers / Feiran Huang [and others] -- Interactions of nanoparticles with proteins : determination of equilibrium constants / Lennart Treuel and Marcelina Malissek -- Tracing the endocytic pathways and trafficking kinetics of cell signaling receptors using single QD nanoparticles / Katye M. Fichter and Tania Q. Vu -- Cellular internalization of quantum dots / Yue-Wern Huang [and others] -- Electrochemical scanning tunneling microscopy and spectroscopy for single-molecule investigation / Andrea Alessandrini and Paolo Facci -- Intracellular delivery of biologically active proteins with peptide-based carriers / Seong Loong Lo and Shu Wang -- Lipo-oligoarginine-based intracellular delivery / Jae Sam Lee and Ching-Hsuan Tung -- Fluorescent spherical monodisperse silica core-shell nanoparticles with a protein-binding biofunctional shell / Achim Weber, Marion Herz, and Gunter E.M. Tovar -- Direct quantification of PTD transduction using real-time monitoring / Mi-Sook Lee and Song Her -- Genotoxic assessment of carbon nanotubes / Olivera Neskovic [and others] -- Separation science : principles and applications for the analysis of bionanoparticles by asymmetrical flow field-flow fractionation (AF4) / Alexandre Moquin, Francoise M. Winnik, and Dusica Maysinger -- Polymersomes-mediated delivery of fluorescent probes for targeted and long-term imaging in live cell microscopy / Irene Canton and Giuseppe Battaglia -- Protocol for the preparation of stimuli-responsive gold nanoparticles capped with elastin-based pentapeptides / Vincent Lemieux, P. Hans H.M. Adams, and Jan C.M. van Hest.
  • 2012 ScienceDirect
    Gilbert, H. J.
    Cellulase refers to a class of enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis. This volume in the Methods in Enzymology series comprehensively covers this topic.
  • 2015 Springer Protocols
    Hempel, Jonathan E.; Hong, Charles C.; Williams, Charles H.
    Identification of Therapeutic Small Molecule Leads in Cultured Cells Using Multiplexed Pathway Reporter Read-outs -- Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles -- Construction and Application of a Photo-cross-linked Chemical Array -- High Content Screening for Modulators of Cardiac Differentiation in Human Pluripotent Stem Cells -- Small Molecule High-Throughput Screening Utilizing Xenopus Egg Extract -- Fission Yeast-based High-throughput Screens for PKA Pathway Inhibitors and Activators -- A Method for High-throughput Analysis of Chronological Aging in Schizosaccharomyces pombe -- Protocols for the Routine Screening of Drug Sensitivity in the Human Parasite Trichomonas vaginalis -- Chemical Genetic Screens Using Arabidopsis thaliana Seedlings Grown on Solid Medium -- Small Molecule Screening Using Drosophila Models of Human Neurological Disorders -- High-throughput Small Molecule Screening in Caenorhabditis elegans -- Whole-organism Screening for Modulators of Fasting Metabolism Using Transgenic Zebrafish -- High Content Screening for Modulators of Cardiovascular or Global Developmental Pathways in Zebrafish -- Extraction Methods of Natural Products from Traditional Chinese Medicines -- Bioassay-guided Identification of Bioactive Molecules from Traditional Chinese Medicines -- NMR Screening in Fragment-Based Drug Design: A Practical Guide -- Practical Strategies for Small Molecule Probe Development in Chemical Biology -- Principal Component Analysis as a Tool for Library Design: A Case Study Investigating Natural Products, Brand-name Drugs, Natural Product-like Libraries, and Drug-like Libraries -- Small Molecule Library Screening by Docking with PyRx -- Fluorous Photoaffinity Labeling to Probe Protein-Small Molecule Interactions -- Identification of the Targets of Biologically Active Small Molecules Using Quantitative Proteomics -- Drug Affinity Responsive Target Stability (DARTS) for Small Molecule Target Identification -- Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action -- Image-Based Prediction of Drug Target in Yeast.
  • v. 1-2, 2004 Wiley
    Cheetham, A. K.; Müller, Achim; Rao, C. N. R.
    v. 1. Nanomaterials : an introduction / C.N.R. Rao, A. Müller, A.K. Cheetham -- Strategies for the scalable synthesis of quantum dots and related nanodimensional materials / Paul O'Brien, N. Pickett -- Moving nanoparticles around : phase-transfer processes in nanomaterials synthesis / M. Sastry -- Mesoscopic assembly and other properties of metal and semiconductor nanocrystals / G.U. Kulkarni, P.J. Thomas, C.N.R. Rao -- Oxide nanoparticles / R. Seshadri -- Sonochemistry and other novel methods developed for the synthesis of nanoparticles / Y. Mastai, A. Gedanken -- Solvothermal synthesis of non-oxide nanomaterials / Y.T. Qian, Y.L. Gu, J. Lu -- Nanotubes and nanowires / A. Govindaraj, C.N.R. Rao -- Synthesis, assembly and reactivity of metallic nanorods / C.J. Murphy ... [et al.] -- Oxide-assisted growth of silicon and related nanowires : growth mechanism, structure and properties / S.T. Lee, R.Q. Zhang, Y. Lifshitz -- v. 2. Electronic structure and spectroscopy of semiconductor nanocrystals / S. Sapra, D.D. Sarma -- Core-shell semiconductor nanocrystals for biological labeling / R.E. Bailey, S. Nie -- Large semiconductor molecules / J.F. Corrigan, M.W. DeGroot -- Oxomolybdates : from structures to functions in a new era of nanochemistry / A. Müller, S. Roy -- Nanostructured polymers / S. Ramakrishnan -- Recent developments in the chemistry and chemical applications of porous silicon / J.M. Schmeltzer, J.M. Buriak -- Nanocatalysis / S. Abbet, U. Heiz -- Nanoporous materials / A.K. Cheetham, P.M. Forster -- Photochemistry and electrochemistry of nanoassemblies / P.V. Kamat -- Electrochemistry with nanoparticles / S. Devarajan, S. Sampath -- Nanolithography and nanomanipulation / A.K. Raychaudhuri.
  • 2005 Springer
    Smith, George Patrick.
  • 2008 CRCnetBASE
    Fukui, Kiichi; Ushiki, Tatsuo.
    Mechanical approaches to elucidate mechanisms of chromosome condensation at the nano- and microlevels / Kazushige Kawabata ... [et al.] -- Development of novel AFM probes for chromosome manipulation / Masato Saito, Gen Hashiguchi and Eiichi Tamiya -- Microchamber array-based sequence-specific DNA detection from a single chromosome via trace volume PCR / Masato Saito and Eiichi Tamiya -- On-chip chromosome sorter using electric and magnetic fields / Takahito Inoue ... [et al.] -- Fluorescence microscopy for analysis of chromosome dynamics / Sachihiro Matsunaga -- Fluorescence in situ hybridization (FISH) as a tool for comparative genomics: application of FISH to studies of chromosome evolution in vertebrates / Yoichi Matsuda ... [et al.] -- Immunocytochemistry for analyzing chromosomes / Osamu Hoshi ... [et al.] -- Proteome analysis of human metaphase chromosomes / Kiichi Fukui and Susumu Uchiyama -- Antipeptide antibodies for examining the conformation and molecular assembly of an intracellular protein / Masatoshi Nakagawa ... [et al.] -- Structure and interactions of the imitation SWI-type chromatin-remodeling complex, ATP-dependent chromatin-assembly facter / Tadayasu Ohkubo ... [et al.] -- Dynamic and functional analysis of chromosomal proteins / Nobuko Ohmido ... [et al.] -- Development of a sustainable chromosome imaging database / Kenji Taniguchi ... [et al.] -- Image database and image analysis of chromosome information / Shin-ichi Toyabe ... [et al.]. Transmission and scanning electron microscopy of mammalian metaphase chromosomes / Sumire Inaga, Keiichi Tanaka and Tatsuo Ushiki -- Atomic force microscopy of human chromosomes in relation to their higher-order structure / Osamu Hoshi, Daisuke Fukushi and Tatsuo Ushiki -- Mechanism of higher-order chromatin folding revealed by AFM observation of in vitro reconstituted chromatin / Kohji Hizume ... [et al.] -- Scanning near-field optical/atomic force microscopy as a tool for simultaneous specification of chromosome topography and particular gene location on the nanometer scale / Motoharu Shichiri ... [et al.] -- Isolation of human and plant chromosomes as nanomaterials / Susumu Uchiyama, Tomoyuki Doi and Kiichi Fukui --
  • 2011 Springer
    Gehl, Julie; Kee, Stephen; Lee, Edward W.
    Introduction to Electroporation -- Electroporation and Cellular Physiology -- The Cell in the Electric Field -- Understanding Electric Fields for Clinical Use -- Generators and Applicators: Equipment for Electroporation -- Cell Electropermeabilization and Cellular Uptake of Small Molecules: The Electrochemotherapy Concept -- Vascular-Disrupting Action of Electrochemotherapy: Mode of Action and Therapeutic Implications -- Electrochemotherapy of Small Tumors; The Experience from the ESOPE (European Standard Operating Procedures for Electrochemotherapy) Group -- Electrochemotherapy for Larger Malignant Tumors -- Cell Electroporation in Bone Tissue -- Drug and Gene Electrotransfer to the Brain -- Minimally Invasive Intraluminal Tumor Ablation -- Electrotransfer of Plasmid DNA -- Gene Electrotransfer to Tumor -- Gene Electrotransfer to Lung -- Gene Electrotransfer to Muscle Tissue: Moving into Clinical Use -- Gene Electrotransfer to Skin -- Electroporation-Mediated DNA Vaccination -- Irreversible Electroporation (IRE) on Liver Tumor Ablation: A Summary of Preclinical Translational Research -- Translational Research on Irreversible Electroporation: VX2 Rabbit Head and Neck -- Clinical Research on Irreversible Electroporation of the Liver.
  • 2013 Springer
    Franke, Andreas G.; Hildt, Elisabeth.
    Medical and Psychosocial Aspects of Cognitive Enhancement -- Pharmacological Neuroenhancement: Substances and Epidemiology / Andreas G. Franke, Klaus Lieb -- Psychopharmacological Neuroenhancement: Evidence on Safety and Efficacy / Dimitris Repantis -- A Bubble of Enthusiasm: How Prevalent Is the Use of Prescription Stimulants for Cognitive Enhancement? / Bradley Partridge -- Modeling the Effects of Modafinil on Selective Attention Electroencephalographic Neural Correlates / Carlos Trenado -- Behavioral Neuroenhancement / Martin Dresler -- The Influence of Sports on Cognitive Task Performance - A Critical Overview / Pavel Dietz -- The Human Experiment: How We Won't Win the Rat Race. What Can We Learn from Brain Stimulation in Humans and Rats About Enhancing the Functional Neurobiology of Higher Cognitive Functions? / Colleen A. Dockery -- Philosophical and Ethical Aspects of Cognitive Enhancement -- Better Brains or Bitter Brains? The Ethics of Neuroenhancement / Kirsten Brukamp -- Cognitive Enhancement - To What End? / Michael Hauskeller -- Nano-bionic Devices for the Purpose of Cognitive Enhancement: Toward a Preliminary Ethical Framework / Frédéric Gilbert -- Cognitive-Enhancing Drugs, Behavioral Training and the Mechanism of Cognitive Enhancement / Emma Peng Chien -- What Is Cognitive Enhancement and Is It Justified to Point Out This Kind of Enhancement Within the Ethical Discussion? / Roland Kipke -- No Pain, No Gain? Objections to the Use of Cognitive Enhancement on the Basis of Its Potential Effects on the Value of Achievement / Lisa Forsberg -- Does the Cognitive Enhancement Debate Call for a Renewal of the Deliberative Role of Bioethics? / Cynthia Forlini, Eric Racine -- Sociological, Political and Legal Aspects of Cognitive Enhancement -- The Biopolitics of Cognitive Enhancement / Peter B. Reiner -- Are We Heading Towards an 'Enhancement Society'? / Armin Grunwald -- Leveling the Playing Field: Fairness in the Cognitive Enhancement Debate / Greta Wagner -- My Mind Is Mine!? Cognitive Liberty as a Legal Concept / Jan-Christoph Bublitz -- Cognitive Enhancement and Criminal Behavior / Elizabeth Shaw -- Enhanced Control and Criminal Responsibility / John Danaher.
  • 2014 ScienceDirect
    Jin, Zhongmin.
    1. Fundamentals of computational modelling of biomechanics in the musculoskeletal system -- 2. Finite element modeling in the musculoskeletal system: generic overview -- 3. Joint wear simulation -- 4. Computational modeling of cell mechanics -- 5. Computational modeling of soft tissues and ligaments -- 6. Computatonal modeling of muscle biomechanics -- 7. Computational modelling of articular cartilage -- 8. Computational modeling of bone and bone remodeling -- 9. Modelling fracture processes in bones -- 10. Modelling fatigue of bone cement -- 11. Modelling fracture processes in orthopaedic implants -- 12. Modelling cementless cup fixation in total hip arthroplasty (THA) -- 13. Computational modeling of hip implants -- 14. Computational modelling of knee implants -- 15. Computational modelling of spinal implants -- 16. Finite element modelling of bone tissue scaffolds -- Index.
  • 2012 Springer
    Karthik, M. V. K.; Shukla, Pratyoosh.
  • 2013 Springer
    Haaker, Rolf G.; Konermann, W.
    Computer-assisted surgery is a growing sub-discipline of orthopaedic surgery. This book offers a comprehensive presentation of scientific work and clinical experience including new technologies like individual templating in unicompartmental and total knee arthoplasty based on computer-assisted design technology. Computer-assisted surgery involves not only total knee and total hip arthroplasty, but also trauma, sports and revision surgery. In this edition we have added sections on 3D fluoroscopy-based spinal surgery as well as 3D fluoroscopy-based trauma surgery. Even in total hip surgery, navigation systems offer exciting new aspects, and the clinical benefit of navigation in total knee arthroplasties has now been demonstrated. We believe that this textbook will be of interest to those new to this specific field, while also providing an update for experienced users. An added benefit is the international character of this textbook, including experiences from Switzerland, Israel, the United States and the German-speaking countries.
  • 2011 Springer
    Gad, Shayne C.; Spainhour, Charles B.
  • 2013 Springer
    Inui, Masayuki; Yukawa, Hideaki.
    Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its "microbial factory" qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
  • 2014 Springer
    DiLorenzo, Nicolas; Lamb, G. Cliff.
    This book addresses the impacts of current and future reproductive technologies on our world food production and provides a significant contribution to the importance of research in the area of reproductive physiology that has never been compiled before. It would provide a unique opportunity to separate the impacts of how reproductive technologies have affected different species and their contributions to food production. Lastly, no publication has been compiled that demonstrates the relationship between developments in reproductive management tools and food production that may be used a reference for scientists in addressing future research areas. During the past 50 years assisted reproductive technologies have been developed and refined to increase the number and quality of offspring from genetically superior farm animal livestock species. Artificial insemination (AI), estrous synchronization and fixed-time AI, semen and embryo cryopreservation, multiple ovulation and embryo transfer (MOET), in vitro fertilization, sex determination of sperm or embryos, and nuclear transfer are technologies that are used to enhance the production efficiency of livestock species.
    Also available: Print – 2014
  • 2010- Wiley
    Current Protocols in Chemical Biology provides validated protocols and overviews about specialized chemical techniques and tools for studies of biology and drug design. These tools include small-molecule design, synthesis, derivatization, handling, and detection as well as advances in laboratory automation, robotics, and medicinal chemistry as applied to high-throughput screening (HTS). Methods for modification of proteins, nucleic acids, carbohydrates and lipids for their use as tools in the study of particular biological systems are also included
  • 2002- Wiley
    Beaucage, Serge L.
  • 2010 Springer
    Shire, Steven J.
    Introduction / Wayne R. Gombotz and Steven J. Shire -- Design of therapeutic MABS. CDR repair: a novel approach to antibody humanization / Mark S. Dennis -- Nanobodies, single-domain antigen-binding fragments of camelid heavy-chain antibodies / Gholamreza Hassanzadeh Ghassabeh, Serge Muyldermans, and Dirk Saerens -- Expression and production of MABS. GPEx® a flexible method for the rapid generation of stable, high expressing, antibody producing mammalian cells lines / Gregory T. Bleck -- Advancing our cell culture platform: incorporating lessons learned and new technologies / Carole Heath -- Recovery and purification. Addressing changes associated with technology transfer: a case study / Michele M. Myers ... [et al.] -- Concepts for disposables in biopharmaceutical manufacture / Joachim K. Walter and Uwe Gottschalk -- Formulation and delivery. Formulation and delivery issues for monoclonal antibody therapeutics / Ann L. Daugherty and Randall J. Mrsny -- Challenges in the development of high protein concentration formulations / Steven J. Shire, Zahra Shahrock, and Jun Liu -- Protein immobilization by crystallization and precipitation: an alternative to lyophilization / Karoline Bechtold-Peters -- Analytics and specification setting for MABS. Characterizing high affinity antigen/antibody complexes by kinetic and equilibrium based methods / Andrew W. Drake, David G. Myszka, and Scott L. Klakamp -- Analytical characterization of monoclonal antibodies: linking structure to function / Reed J. Harris ... [et al.] -- Analysis of irreversible aggregation, reversible self-association and fragmentation of monoclonal antibodies by analytical ultracentrifugation / James D. Andya, Jun Liu, and Steven J. Shires -- Biophysical signatures of monoconal antibodies / N. Harn ... [et al.] -- Pharmacokinetics and immunogenicity. Impact of Fc glycosylation on monoclonal antibody effector functions and degradation by proteases / T. Shantha Raju -- Immunogenicity assessment of antibody therapeutics / P. stas, Y. Gansemans, and I. Lasters -- Armed antibodies and new classes of antibodies. Production of monoclonal antibodies in E. coli / Dorothea E. Reilly and Daniel G. Yansura -- Recent advances in the use of antibody drug conjugates for cancer theapy / Peter D. Senter -- Antibody radiolabeling / Corinne Bensimon and Russell Redshaw.
  • 2010 CRCnetBASE
    Kisaalita, William Ssempa.
    "This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
  • 2015 Springer
    Balakrishnan, Nikhil.
    1. The Principles of Dependability -- 2. System Safety Assessment -- 3. Fault Tree Analysis -- 4. Failure Modes and Effects Analysis -- 5. Machine Learning Methods with Applications to Diagnosis -- 6. Byzantine Medical Problems: Decision Making with Misleading, Imperfect Information -- 7. Process Driven Methods in Diagnosis and Treatment -- 8. Toyota Production System -- 9. Reliance Implementation Methods Applied to a Kaizen Project -- 10. Knowledge & Culture.
  • 2002 Wiley
    Brakmann, Susanne; Johnsson, Kai.
    ch. 1. Introduction, p. 1-3 / Kai Johnsson and Susanne Brakmann, p. 1-3 -- ch. 2. Evolutionary Biotechnology - From Ideas and Concepts to Experiments and Computer Simulations / Peter Schuster, p. 5-28 -- ch. 3. Using Evolutionary Strategies to Investigate the Structure and Function of Chorismate Mutases / Donald Hilvert, Sean V. Taylor and Peter Kast, p. 29-62 -- ch. 4. Construction of Environmental Libraries for Functional Screening of Enzyme Activity / Rolf Daniel, p. 63-78 -- ch. 5. Investigation of Phage Display for the Directed Evolution of Enzymes / Patrice Soumillion and Jacques Fastrez, p. 79-110 -- ch. 6. Directed Evolution of Binding Proteins by Cell Surface Display: Analysis of the Screening Process / K. Dane Wittrup, p. 111-126 -- ch. 7. Yeast n-Hybrid Systems for Molecular Evolution / Brian T. Carter, Hening Lin and Virginia W. Cornish, p. 127-158 -- ch. 8. Advanced Screening Strategies for Biocatalyst Discovery / Andreas Schwienhorst, p. 159-175 -- ch. 9. Engineering Protein Evolution / Stefan Lutz and Stephen J. Benkovic, p. 177-213 -- ch. 10. Exploring the Diversity of Heme Enzymes through Directed Evolution / Patrick C. Cirino and Frances H. Arnold, p. 215-243 -- ch. 11. Directed Evolution as a Means to Create Enantioselective Enzymes for Use in Organic Chemistry / Manfred T. Reetz and Karl-Erich Jaeger, p. 245-279 -- ch. 12. Applied Molecular Evolution of Enzymes Involved in Synthesis and Repair of DNA / John F. Davidson, Jon Anderson, Haiwei Guo, Daniel Landis and Lawrence A. Loeb, p. 281-307 -- ch. 13. Evolutionary Generation Versus Rational Design of Restriction Endonucleases with Novel Specificity / Thomas Lanio, Albert Jeltsch and Alfred Pingoud, p. 309-327 -- ch. 14. Evolutionary Generation of Enzymes with Novel Substrate Specificities / Uwe T. Bornscheuer, p. 329-341.
  • 2013 Springer
    Barciszewski, Jan; Erdmann, V. A.
    DNA and RNA nanobiotechnologies have currently reached the status of one of the most dynamic research areas in the field of drug delivery in molecular medicine. Scientists and bio-engineers are creating totally new nanometer-scale structures with unique biological properties for a wide range of medical applications. The book, written by world-leading scientists in this new field, gives an overview of various aspects and applications of DNA and RNA nanotechnologies. These include the design and synthesis of DNA and RNA nanostructures with the aim of using them for different kinds of drug deliveries, for genetic immunization, for metabolite and nucleic acid detection, gene regulation, siRNA delivery for cancer treatment, and even analytical and therapeutic applications of aptamer-based nanoparticles. This volume will be of interest not only to graduate students and researchers in the field of molecular medicine and molecular biology, but also to chemists interested in the biological fields. As a matter of fact, the book contains so many new and unique approaches to this area of molecular medicine that it may inspire the interested reader to undertake research into nucleic acid nanotechnologies.
  • 2012 Springer Protocols
    Alonso, Antonio.
    An overview of DNA typing methods for human identification : past, present, and future / Robyn Thompson, Silvia Zoppis, and Bruce McCord -- Capillary electrophoresis and 5-channel LIF detection of a 26plex autosomal STR asay for human identification / Carolyn R. Hill -- Capillary electrophoresis of miniSTR markers to genotype highly degraded DNA samples / Michael D. Coble -- Interpretation guidelines of a standard Y-chromosome STR 17-plex PCR-CE assay for crime casework / Lutz Roewer and Maria Geppert -- Capillary electrophoresis of an X-chromosome STR decaplex for kinship deficiency cases / Leonor Gusmão [and others] -- A 48-plex autosomal SNP GenPlex Assay for human individualization and relationship testing / Carmen Tomas, Claus Børsting, and Niels Morling -- Typing of 49 autosomal SNPs by single base extension and capillary electrophoresis for forensic genetic testing / Claus Børsting, Carmen Tomas, and Niels Morling -- A 34-plex autosomal SNP single base extension assay for ancestry investigations / C. Phillips, M. Fondevila, and Maria Victoria Lareau -- SNaPshot® minisequencing analysis of multiple ancestry-informative Y-SNPs using capillary electrophoresis / Maria Geppert and Lutz Roewer -- Capillary electrophoresis of 38 noncoding biallelic mini-indels for degraded samples and as complementary tool in paternity testing / Rui Pereira and Leonor Gusmão -- Capillary electrophoresis of an 11-plex mtDNA coding region SNP single base extension assay for discrimination of themost common caucasian HV1/HV2 mitotype / Peter M. Vallone -- Capillary electrophoresis of a multiplex reverse transcription-polymerase chain reaction to target messenger RNA markers for body fluid identification / Cordula Haas, Erin Hanson, and Jack Ballantyne -- DNA extraction from aged skeletal samples for STR typing by capillary electrophoresis / René Huel [and others] -- Interpretation guidelines for multilocus STR forensic profiles from low template DNA samples / Zoran M. Budimlija and Theresa A. Caragine -- Interpretation guidelines for mixed-STR multilocus electrophoretic profiles / Juan Antonio Luque -- Capillary electrophoresis analysis of a 9-plex STR assay for canine genotyping / Barbara van Asch and António Amorim -- Capillary electrophoresis of DNA from Cannabis sativa for correlation of samples to geographic origin / Heather Mller Coyle -- Capillary electrophoresis of multigene barcoding chloroplast markers for species identification of botanical trace evidence / Gianmarco Ferri, Beatrice Corradini, and Milena Alù -- Capillary electrophoresis of big-dye terminator sequencing reactions for human mtDNA control region haplotyping in the identification of human remains / Marta Montesino and Lourdes Prieto -- Capillary electrophoresis of human mtDNA control region sequences from highly degraded samples using short mtDNA amplicons / Odile M. Loreille and Jodi A. Irwin -- Interpretation guidelines of mt DNA control region sequence electropherograms in forensic gnetics / Manuel Crespillo Marquez -- Capillary electrophoresis of mtDNA cytochrome b gene sequences for animal species identification / Adrian Linacre -- Sequence analysis of the canine mitochondrial DNA control region from shed hair samples in criminal investigations / C. Berger, B. Berger, and W. Parson -- Integrated sample cleanup and microchip capillary array electrophoresis for high-performance forensic STR profiling / Peng Liu [and others] -- Microchip capillary electrophoresis protocol to evaluate quality and quantity of mtDNA amplified fragments for DNA sequencing in forensic genetics / Coro Fernández and Antonio Alonso -- Microchip capillary electrophoresis of multi-locus VNTR analysis for genotyping of Bacillus anthracis and Yersinia pestis in microbial forensic cases / Andrea Ciammaruconi.
  • 2011 Springer Protocols
    Samori', B.; Zuccheri, Giampaolo.
    Synthesis and characterization of self-assembled DNA nanostructures / Chenxiang Lin [and others] -- Protocols for self-assembly and imaging of DNA nanostructures / Thomas L. Sobey and Friedrich C. Simmel -- Self-assembly of metal-DNA triangles and DNA nanotubes with synthetic junctions / Hua Yang [and others] -- DNA-templated Pd conductive metallic nanowires / Khoa Nguyen, Stephane Campidelli, and Arianna Filoramo -- Method to map spatiotemporal pH changes inside living cells using a pH-triggered DNA nanoswitch / Souvik Modi and Yamuna Krishnan -- Control of helical handedness in DNA and PNA nanostructures / Roberto Corradini [and others] -- G-quartet, G-quadruplex, and G-wire regulated by chemical stimuli / Daisuke Miyoshi and Naoki Sugimoto -- Preparation and atomic force microscopy of quadruplex DNA / James Vesenka -- Synthesis of long DNA-based nanowires / Alexander Kotlyar -- G-wire synthesis and modification with gold nanoparticle / Christian Leiterer, Andrea Csaki, and Wolfgang Fritzsche -- Preparation of DNA nanostructures with repetitive binding motifs by rolling circle amplification / Edda Rei⁷, Ralph Holzel, and Frank F. Bier -- Controlled confinement of DNA at the nanoscale : nanofabrication and surface bio-functionalization / Matteo Palma [and others] -- Templated assembly of DNA origami gold nanoparticle arrays on lithographically patterned surfaces / Albert M. Hung and Jennifer N. Cha -- DNA-modified single crystal and nanoporous silicon / Andrew Houlton [and others] -- Atomic force microscopy as a lithographic tool : nanografting of DNA nanostructures for biosensing applications / Matteo Castronovo and Denis Scaini -- Trapping and immobilization of DNA molecules between nanoelectrodes / Anton Kuzyk, J. Jussi Toppari, and Paivi Torma -- DNA contour length measurements as a tool for the structural analysis of DNA and nucleoprotein complexes / Claudio Rivetti -- DNA molecular handles for single-molecule protein-folding studies by optical tweezers / Ciro Cecconi [and others] -- Optimal practices for surface-tethered single molecule total internal reflection fluorescence resonance energy transfer analysis / Matt V. Fagerburg and Sanford H. Leuba -- Engineering mononucleosomes for single-pair FRET experiments / Wiepke J.A. Koopmans, Ruth Buning, and John van Noort -- Measuring DNA-protein binding affinity on a single molecule using optical tweezers / Micah J. McCauley and Mark C. Williams -- Modeling nanopores for sequencing DNA / Jeffrey R. Comer, David B. Wells, and Aleksei Aksimentiev.
  • 2013 Springer
    Durvasula, Ravi; Sree Hari Rao, Vadrevu.
    This book covers modeling of insect vector-borne infectious diseases, which account for some three million deaths worldwide. The authors describe processes for quantifying the vital parameters of diseases transmitted by mosquitoes, sand flies, fleas and ticks. Despite great advances in public health worldwide, insect vector-borne infectious diseases remain a leading cause of morbidity and mortality. Diseases that are transmitted by arthropods such as mosquitoes, sand flies, fleas, and ticks affect hundreds of millions of people and account for nearly three million deaths all over the world. In the past there was very little hope of controlling the epidemics caused by these diseases, but modern advancements in science and technology are providing a variety of ways in which these diseases can be handled. Clearly, the process of transmission of an infectious disease is a nonlinear dynamic process which can be understood only by appropriately quantifying the vital parameters that govern these dynamics --c Source other than Library of Congress.
  • 2013 Springer
    Durvasula, Ravi; Sree Hari Rao, Vadrevu.
    This book covers modeling of insect vector-borne infectious diseases, which account for some three million deaths worldwide. The authors describe processes for quantifying the vital parameters of diseases transmitted by mosquitoes, sand flies, fleas and ticks. Despite great advances in public health worldwide, insect vector-borne infectious diseases remain a leading cause of morbidity and mortality. Diseases that are transmitted by arthropods such as mosquitoes, sand flies, fleas, and ticks affect hundreds of millions of people and account for nearly three million deaths all over the world. In the past there was very little hope of controlling the epidemics caused by these diseases, but modern advancements in science and technology are providing a variety of ways in which these diseases can be handled. Clearly, the process of transmission of an infectious disease is a nonlinear dynamic process which can be understood only by appropriately quantifying the vital parameters that govern these dynamics.
  • 2009 Springer
    Bal, Thierry; Destexhe, Alain.
  • 2005 Springer
    Matranga, Valeria.
    Are echinoderms of interest to biotechnology? / C. Petzelt -- Cell adhesion and communication : a lesson from echinoderm embryos for the exploitation of new therapeutic tools / F. Zito ... [et al.] -- Cell signalling during sea urchin development : a model for assessing toxicity of environmnetal contaminants / C. Angelini ... [et al.] -- Echinoderm reactive oxygen species (ROS) production measured by peroxidase, luminol-enhanced chemiluminescence (PLCL) as an immunotoxicological tool / G. Coteur, B. Danis, P. Dubois -- Monitoring chemical and physical stress using sea urchin immune cells / V. Matranga ... [et al.] -- DNA damage and developmental defects after exposure to UV and heavy metals in sea urchin cells and embryos compared to other invertebrates / H.C. Schröder ... [et al.] -- Echinoderms : their culture and bioactive compounds / M.S. Kelly -- Regenerative response and endocrine disrupters in crinoid echinoderms : an old experimental model, a new ecotoxicological test / M.D. Candia Carnevali -- Echinoderm adhesive secretions : from experimental characterization to biotechnological applications / P. Flammang, R. Santos, D. Haesaerts -- Mutable collagenous tissue : overview and biotechnological perspective / I.C. Wilkie -- Bioresources from echinoderms / Y. Yokota.

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