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Biomedical EngineeringAccess restricted to Stanford unless otherwise noted

  • "Extra-ordinary" ergonomics 2006, CRCnetBASE
  • "This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
  • "A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last several decades, this book discusses the theoretical and experimental evidence and considerations the effects of strong electromagnetic fields and/or electric pulses and their importance in medicine and biology. The authors present the basic techniques applied in electroporation and the advanced methods for creation of nanopores, highlighting their basic science and clinical applications. Topics include nano electroporation, classic electroporation, experimental evidence for electroporation of living cells, and electroporation for cancer and wound healing"--Provided by publisher.
  • Cell Adhesions and Signaling: A Tool for Biocompatibility Assessment / Roumen Pankov and Albena Momchilova -- Development of Provisional Extracellular Matrix on Biomaterials Interface: Lessons from In Vitro Cell Culture / George Altankov, Thomas Groth, Elisabeth Engel, Jonas Gustavsson and Marta Pegueroles, et al. -- Endothelial Progenitor Cells for Tissue Engineering and Tissue Regeneration Endothelial Progenitor Cells / Joyce Bischoff -- Dermal Precursors and the Origins of the Wound Fibroblast / Jeffrey M. Davidson -- Cell Based Therapies: What Do We Learn from Periosteal Osteochondrogenesis? / Peter J. Emans, Tim J. M. Welting and Venkatram Prasad Shastri -- Bioreactor Systems in Regenerative Medicine / Ivan Martin, Stefania A. Riboldi and David Wendt -- Biomimetic Approaches to Design of Tissue Engineering Bioreactors / Bojana Obradovic, Milica Radisic and Gordana Vunjak-Novakovic -- The Nature of the Thermal Transition Influences the Shape-Memory Behavior of Polymer Networks / Andreas Lendlein, Marc Behl and Stefan Kamlage -- Nanoengineered Systems for Regenerative Medicine Surface Engineered Polymeric Biomaterials with Improved Bio-Contact Properties / Todorka Vladkova and Natalia Krasteva -- Nanocomposites for Regenerative Medicine / Ryan Hoshi, Antonio R. Webb, Hongjin Qiu and Guillermo A. Ameer -- Role of Spatial Distribution of Matricellular Cues in Controlling Cell Functions / Daniela Guarnieri and Paolo A. Netti -- Materials Surface Effects on Biological Interactions / Josep A. Planell, Melba Navarro, George Altankov, Conrado Aparicio and Elisabeth Engel, et al. -- Chemical and Physical Modifications of Biomaterial Surfaces to Control Adhesion of Cells / Thomas Groth, Zhen-Mei Liu, Marcus Niepel, Dieter Peschel and Kristin Kirchhof, et al. -- Results of Biocompatibility Testing of Novel, Multifunctional Polymeric Implant Materials In-Vitro and In-Vivo / Dorothee Rickert, Rosemarie Fuhrmann, Bernhard Hiebl, Andreas Lendlein and Ralf-Peter Franke -- UFOs, Worms, and Surfboards: What Shapes Teach Us About Cell-Material Interactions / Julie A. Champion and Samir Mitragotri -- Nano-engineered Thin Films for Cell and Tissue-Contacting Applications / Richard F. Haglund -- Injectable Hydrogels: From Basics to Nanotechnological Features and Potential Advances / Biancamaria Baroli -- Polyelectrolyte Complexes as Smart Nanoengineered Systems for Biotechnology and Gene Delivery / Vladimir A. Izumrudov.
  • The presence of oriented features in images often conveys important information about the scene or the objects contained; the analysis of oriented patterns is an important task in the general framework of image understanding. As in many other applications of computer vision, the general framework for the understanding of oriented features in images can be divided into low- and high-level analysis. In the context of the study of oriented features, low-level analysis includes the detection of oriented features in images; a measure of the local magnitude and orientation of oriented features over the entire region of analysis in the image is called the orientation field. High-level analysis relates to the discovery of patterns in the orientation field, usually by associating the structure perceived in the orientation field with a geometrical model. This book presents an analysis of several important methods for the detection of oriented features in images, and a discussion of the phase portrait method for high-level analysis of orientation fields. In order to illustrate the concepts developed throughout the book, an application is presented of the phase portrait method to computer-aided detection of architectural distortion in mammograms.
  • Antibody engineering 2004, Springer Protocols
  • Analysis for internal fixation of a fractured bone by means of bone-fixator plate -- Human lumbar vertebral body : analysis of its functionally optimal design -- Human spinal intervertebral disc : optimal structural design characteristics -- Biomechanics of fitness index : optimal walking and jogging modes, and hip joint assessment -- Analysis of spinning ball trajectories of soccer kicks and basketball throws -- Mechanics of baseball pitching and batting -- Biodynamics analysis of women's gymnastics : Yurchenko layout vault.Biomechanics in medical diagnosis in the form of nondimensional physiological indices -- Left ventricular mechanics -- Left ventricular contractility indices -- Vascular biomechanics -- Lung ventilation modeling for lung disease diagnosis -- Lung gas-transfer performance analysis -- Indicators for extubation of mechanically ventilated COPD patients using lung ventilation modeling -- Glucose-insulin dynamics modeling -- Glucose tolerance tests modeling -- Modeling of OGTT blood glucose and insulin responses and diagnostic indices --
  • Artificial muscles 2007, CRCnetBASE
  • Artificial organs 2009, Springer
  • Artificial heart valves -- Artificial heart and cardiac assist devices -- Cardiac pacemakers -- Dialysis.
  • Artificial sight 2007, Springer
  • Auditory prostheses 2011, Springer
    1. Advances in Auditory Prostheses / Fan-Gang Zeng -- 2. Bilateral Cochlear Implants / Richard van Hoesel -- 3. Combining Acoustic and Electric Hearing / Christopher W. Turner and Bruce J. Gantz -- 4. Implantable Hearing Devices for Conductive and Sensorineural Hearing Impairment / Ad Snik -- 5. Vestibular Implants / Justin S. Golub, James O. Phillips, and Jay T. Rubinstein -- 6. Optical Stimulation of the Auditory Nerve / Claus-Peter Richter and Agnella Izzo Matic -- 7. A Penetrating Auditory Nerve Array for Auditory Prosthesis / John C. Middlebrooks and Russell L. Snyder -- 8. Cochlear Nucleus Auditory Prostheses / Douglas B. McCreery and Steven R. Otto -- 9. Midbrain Auditory Prostheses / Hubert H. Lim, Minoo Lenarz, and Thomas Lenarz -- 10. Central Auditory System Development and Plasticity After Cochlear Implantation / Anu Sharma and Michael Dorman -- 11. Auditory Training for Cochlear Implant Patients / Qian-Jie Fu and John J. Galvin III -- 12. Spoken and Written Communication Development Following Pediatric Cochlear Implantation / Sophie E. Ambrose, Dianne Hammes-Ganguly, and Laurie S. Eisenberg -- 13. Music Perception / Hugh McDermott -- 14. Tonal Languages and Cochlear Implants / Li Xu and Ning Zhou -- 15. Multisensory Processing in Cochlear Implant Listeners / Pascal Barone and Olivier Deguine.
  • Back and bed 2005, CRCnetBASE
  • Bio-MEMS 2007, CRCnetBASE
  • Biomaterials 2007, CRCnetBASE
    Metallic biomaterials / Joon B. Park and Young Kon Kim -- Ceramic biomaterials / W.C. Billotte -- Polymeric biomaterials / Hai Bang Lee, Gilson Khang, and Jin Ho Lee -- Composite biomaterials / Roderic S. Lakes -- Biodegradable hydrogels : tailoring properties and function through chemistry and structure / Andrew T. Metters and Chien-Chi Lin -- Biodegradable polymeric biomaterials : an updated overview / Chih-Chang Chu -- Biologic biomaterials : tissue-derived biomaterials (collagen) / Shu-Tung Li -- Soft tissue replacements / K.B. Chandran, K.J.L. Burg, and S.W. Shalaby -- Hard tissue replacements / Sang-Hyun Park ... [et al.] -- Controlling and assessing cell-biomaterial interactions at the micro- and nanoscale : applications in tissue engineering / Jessica Kaufman, Joyce Y. Wong, and Catherine Klapperich.
  • Biomaterials 2002, CRCnetBASE
  • Electrohydrodynamic processing of micro- and nanometer biological materials / Yiquan Wu and Robert Lewis Clark -- Fabrication and function of biohybrid nanomaterials prepared via supramolecular approaches / Katsuhiko Ariga -- Polypyrrole nano- and microsensors and actuators for biomedical applications / Yevgeny Berdichevsky and Yu-Hwa Lo -- Processing of biosensing materials and biosensors / Yingchun Zhu, Yu Yang, and Yanyan Liu -- Synthetic and natural degradable polymeric biomaterials / Sanjukta Deb -- Electroactive polymers as smart materials with intrinsic actuation properties: new functionalities for biomaterials / Federico Carpi and Danilo De Rossi -- Blood contacting surfaces / Menno L.W. Knetsch -- Improving blood compatibility of biomaterials using a novel antithrombin-heparin covalent complex / Leslie Roy Berry and Anthony Kam Chuen Chan -- Surface modification of biomaterials using plasma immersion ion implantation and deposition / Xuanyong Liu, Ricky K.Y. Fu, Paul K. Chu -- Biomaterials for gastrointestinal medicine, repair and reconstruction / Richard M. Day -- Biomaterials for cartilage reconstruction and repair / Wojciech Swieszkowski ... [et al.].Inorganic and composite bioactive scaffolds for bone tissue engineering / Q.Z. Chen, Oana Bretcanu, Aldo R. Boccaccini -- Design, fabrication and characterization of scaffolds via solid free-form fabrication techniques / Dietmar W. Hutmacher and Maria Ann Woodruff -- Control and monitoring of scaffold architecture for tissue engineering / Ying Yang ... [et al.] -- Rapid prototyping methods for tissue engineering applications / Giovanni Vozzi and Arti Ahluwalia -- Design and fabrication principles of electrospinning of scaffolds / Dietmar W. Hutmacher and Andrew K. Ekaputra -- Nanoparticles in cancer drug delivery systems / So Yeon Kim and Young Moo Lee -- Polymeric nano/microparticles for oral delivery of proteins and peptides / S. Sajeesh and Chandra P. Sharma -- Nanostructured porous biomaterials for controlled drug release systems / Yang Yang Li, Jifan Li, and Bunichiro Nakajima -- Inorganic nanostructures for drug delivery / Ying-Jie Zhu -- Self-assembly of nanostructures as biomaterials / Hua Ai, Yujiang Fan, and Zhongwei Gu --
  • Biomaterials. 3rd ed. 2007, Springer
  • Biomechanics for life 2011, Springer
  • Introduction -- Chemistry and structure of dendrimers. Definition of terms and nomenclature ; Sugar code (glyc code) ; Classes of peptide-, glyco, and glycopeptide dendrimers ; The dendritic state and dendritic effects ; Synthesis of dendrimers : convergent and divergent approaches ; Purification and characterization of dendrimers ; Dendrimeric libraries ; Dendrimers in catalysis -- Dendrimers and their biological and therapeutic applications. Dendrimers and solubility ; Biocompability and toxicity of dendrimers ; Dendrimers in nanoscience and nanotechnology ; Dendrimers in drug delivery ; Dendrimers in gene delivery ; Dendrimers and bacteria ; Dendrimers and viruses ; Dendrimers and parasites ; Cancer ; Diagnostics, lectin detection and cell-cell interactions ; Dendrimers as biosensors and imaging tools ; Dendrimers regulating in intracellular signaling pathways ; Vaccines and immunomodulation ; Dendrimers in neurodegenerative diseases ; Conclusions and perspectives. .
  • Sect. I. Physiologic systems. An outline of cardiovascular structure and function -- Endocrine system -- Nervous system -- Vision system -- Auditory system -- Gastrointestinal system -- Respiratory system -- sect. II. Physiological modeling, simulation, and control. Modeling strategies and cardiovascular dynamics -- Compartmental models of physiologic systems -- Cardiovascular models and control -- Respiratory models and control -- Neural networks for physiological control -- Methods and tools for identification of physiologic systems -- Autoregulating windkessel dynamics may cause low frequency oscillations -- External control of movements -- The fast eye movement control system -- A comparative approach to analysis and modeling of cardiovascular function -- Cardiopulmonary resuscitation: biomedical and biophysical analyses -- sect. III. Bioelectric phenomena. Basic electrophysiology -- Volume conductor theory -- The electrical conductivity of tissues -- Membrane models -- Computaitonal methods and software for bioelectric field problems -- Principles of electrocardiography -- Principles of electromyography -- Principles of electroencephalography -- Biomagnetism -- Electrical stimulation of excitable systems -- sect. IV. Neuroengineering. History and overview of neural engineering -- Electrical stimulation of the central nervous system -- Transcutaneous FES for ambulation: the parastep system -- Comparing electrodes for use as cortical control signals: tiny tines, tiny wires, or tiny cones on wires: which is best? -- Development of a multi-functional 22-channel functional electrical stimulator for paraplegia -- An implantable bionic network of injectable neural prosthetic devices: the future platform for functional electrical stimulation and sensing to restore movement and sensation -- Visual prostheses -- Interfering with the genesis and propagation of epileptic seizures by neuromodulation -- Transcranial magnetic stimulation of deep brain regions -- sect. V. Biomaterials. Metallic biomaterials -- Ceramic biomaterials -- Polymeric biomaterials -- Composite biomaterials -- Biodegradable polymeric biomaterials: an updated overview -- Biologic biomaterials: tissue-derived biomaterials (collagen) -- Soft tissue replacements -- Hard tissue replacements -- Controlling and assessing cell-biomaterial interactions at the micro- and nanoscale: applications in tissue engineering -- sect. VI. Biomechanics. Mechanics of hard tissue -- Musculoskeletal soft tissue mechanics -- Joint-articulating surface motion -- Joint lubrication -- Analysis of gait -- Mechanics of head/neck -- Biomechanics of chest and abdomen impact -- Cardiac biomechanics -- Heart valve dynamics -- Arterial macrocirculatory hemodynamics -- Mechanics of blood vessels -- The venous system -- Mechanics, molecular transport, and regulation in the microcirculation -- Mechanics and deformability of hematocytes -- Mechanics of tissue/lymphatic transport -- Modeling in cellular biomechanics -- Cochlear mechanics -- Vestibular mechanics -- Exercise physiology -- Factors affecting mechanical work in humans -- sect. VII. Rehabilitation engineering. Rehabilitation engineering, science, and technology -- Orthopedic prosthetics and orthotics in rehabilitation -- Wheeled mobility: wheelchairs and personal transportation -- Externally powered and controlled orthoses and prostheses -- Sensory augmentation and substitution -- Augmentative and alternative communication -- Measurement tools and processes in rehabilitation engineering -- Rehabilitation engineering technologies: principles of application -- sect. VIII. Human performance engineering. The elemental resource model for human performance -- Measurement of neuromuscular performance capacities -- Measurement of sensory-motor control performance capacities: tracking tasks -- Measurement of information-processing subsystem performance capacities -- High-level task analysis: cognitive components -- Task analysis and decomposition: physical components -- Human-computer interaction design -- Applications of human performance measurements to clinical trials to determine therapy effectiveness and safety -- Applications of quantitative assessment of human performance in occupational medicine -- Human performance engineering design and analysis tools -- Human performance engineering: challenges and prospects for the future -- sect. IX. Ethics. Beneficence, nonmaleficence, and medical technology -- Ethical issues related to clinical research.
  • Biomedical image analysis 2005., CRCnetBASE
  • Biomedical polymers 2007, CRCnetBASE
  • Biomedical Signals and Systems is meant to accompany a one-semester undergraduate signals and systems course. It may also serve as a quick-start for graduate students or faculty interested in how signals and systems techniques can be applied to living systems. The biological nature of the examples allows for systems thinking to be applied to electrical, mechanical, fluid, chemical, thermal and even optical systems. Each chapter focuses on a topic from classic signals and systems theory: System block diagrams, mathematical models, transforms, stability, feedback, system response, control, time and frequency analysis and filters. Embedded within each chapter are examples from the biological world, ranging from medical devices to cell and molecular biology. While the focus of the book is on the theory of analog signals and systems, many chapters also introduce the corresponding topics in the digital realm. Although some derivations appear, the focus is on the concepts and how to apply them. Throughout the text, systems vocabulary is introduced which will allow the reader to read more advanced literature and communicate with scientist and engineers. Homework and Matlab simulation exercises are presented at the end of each chapter and challenge readers to not only perform calculations and simulations but also to recognize the real-world signals and systems around them.
  • Evaluating biomedical technology poses a significant challenge in light of the complexity and rate of introduction in today's healthcare delivery system. Successful evaluation requires an integration of clinical medicine, science, finance, and market analysis. Little guidance, however, exists for those who must conduct comprehensive technology evaluations. The 3Q Method meets these present day needs. The 3Q Method is organized around 3 key questions dealing with 1) clinical and scientific basis, 2) financial fit and 3) strategic and expertise fit. Both healthcare providers (e.g., hospitals) and medical industry providers can use the Method to evaluate medical devices, information systems and work processes from their own perspectives. The book describes the 3Q Method in detail and provides additional suggestions for optimal presentation and report preparation.
  • Biopacemaking 2007, Springer
  • Biosensors and biodetection v. 1-2, 2009, Springer Protocols
    v. 2, 2009 Springer Protocols
    V. 1. Optical-based detectors. Pt. I. Optical-based detectors. Surface plasmon resonance and surface plasmon field-enhanced fluorescence spectroscopy for sensitive detection of tumor markers / Yusuke Arima ... [et al.] -- Surface plasmon resonance biosensor for biomolecular interaction analysis based on spatial modulation phase detection / Xiang Ding, Fangfang Liu, and Xinglong Yu -- Array-based spectral SPR biosensor: analysis of mumps virus infection / Jong Seol Yuk and Kwon-Soo Ha -- Optical biosensors based on photonic crystal surface waves / Valery N. Konopsky and Elena V. Alieva -- Surface plasmon resonance biosensing / Marek Piliarik, Hana Vaisocherová, and Jiří Homola -- Label-free detection with the resonant mirror biosensor / Mohammed Zourob ... [et al.] -- Label-free detection with the liquid core optical ring resonator sensing platform / Ian M. White ... [et al.] -- Reflectometric interference spectroscopy / Guenther Proll ... [et al.] -- Phase sensitive interferometry for biosensing applications / Digant P. Davé -- Label-free serodiagnosis on a grating coupler / Thomas Nagel, Eva Ehrentreich-Förster, and Frank F. Bier -- Pt. II. Indirect detectors. CCD camera detection of HIV infection / John R. Day --Integrating waveguide biosensor / Shuhong Li ... [et al.] -- Detection of fluorescence generated in microfluidic channel using in-fiber grooves and in-fiber microchannel sensors / Rudi Irawan and Swee Chuan Tjin -- Multiplex integrating waveguide sensor: SignalyteTM-II / Shuhong Li ... [et al.] -- CCD based fiber-optic spectrometer detection / Rakesh Kapoor -- V. 2. Electrochemical and mechanical detectors, lateral flow and ligands for biosensors. Pt. I. Mechanical detectors. A set of piezoelectric biosensors using cholinesterases / Carsten Teller ... [et al.] -- Piezoelectric biosensors for aptomer-protein interaction / Sara Tombelli ... [et al.] -- Piezoelectric quartz crystal resonators applied for immunosensing and affinity interaction studies / Petr Skládal -- Biosensors based on cantilevers / Mar Alvarez ... [et al.] -- Piezoelectric-excited millimeter-sized cantilever biosensors / Raj Mutharasan -- Pt. II. Electrochemical detectors. Preparation of screen-printed electrochemical immunosensors for estradiol, and their application in biological fluids / Roy M. Pemberton and John P. Hart -- Electrochemical DNA biosensors: protocols for intercalator-based detection of hybridization in solution and at the surface / Kagan Kerman, Mun'delanji Vestergaard, and Eiichi Tamiya --Electrochemical biosensor technology: application to pesticide detection / Ilaria Palchetti, Serena Laschi, and Marco Mascini -- Electrochemical detection of DNA hybridization using micro and nanoparticles / María Teresa Castañeda, Salvador Alegret, and Arben Merkuçi -- Electrochemical immunosensing using micro and nanoparticles / Alfredo de la Escosura-Muñiz ... [et al.] -- Methods for the preparation of electrochemical composite biosensors based on gold nanparticles / A. González-Cortés, P. Yáñez-Sedeño, and J.M. Pingarrón -- Pt. III. Lateral flow. Immunochromatographic lateral flow strip tests / Gaiping Zhang, Junqing Guo, Xuannian Wang -- Liposome-enhanced lateral-flow assays for the sandwich-hybridization detection of RNA / Katie A. Edwards and Antje J. Baeumner -- Rapid prototyping of lateral flow assays / Alexander Volkov ... [et al.] -- Lateral flow colloidal gold-based immunoassay for pesticide / Shuo Wang, Can Zhang, and Yan Zhang -- Pt. IV. Ligands. Synthesis of a virus electrode for measurement of prostate specific membrane antigen / Juan E. Diaz ... [et al.] --Simple luminescence detector for capillary electrophoresis / Antonio Segura-Carretero, Jorge F. Fernández-Sánchez, and Alberto Fernández-Gutiérrez -- Optical system design for biosensors based on CCD detection / Douglas A. Christensen and James N. Herron --A simple portable electroluminescence illumination-based CCD detector / Yordan Kostov ... [et al.] -- Fluoroimmunoassays using the NRL array biosensor / Joel P. Golden and Kim E. Sapsford -- Biosensors technologies: acousto-optic tunable filter-based hyperspectral and polarization images for fluorescence and spectroscopic imaging / Neelam Gupta -- Photodiode-based detection system for biosensors / Yordan Kostov -- Photodiode array on-chip biosensor for the detection of E. coli O157:H7 pathogenic bacteria / Joon Myong Song and Ho Taik Kwon -- DNA analysis with a photo-diode array sensor / Hideki Kambara and Guohua Zhou -- Miniaturized and integrated fluorescence detectors for microfluidic capillary electrophoresis devices / Toshihiro Kamei -- Photomultiplier tubes in biosensors / Yafeng Guan --In vivo bacteriophage display for the discovery of novel peptide-based tumor-targeting agents / Jessica R. Newton and Susan L. Deutscher -- Biopanning of phage displayed peptide libraries for the isolation of cell-specific ligands / Michael J. McGuire, Shunzi Li, and Kathlynn C. Brown -- Biosensor detection systems: engineering stable, high-affinity bioreceptors by yeast surface display / Sarah A. Richman, David M. Kranz, and Jennifer D. Stone -- Antibody affinity optimization using yeast cell surface display / Robert W. Siegel -- Using RNA aptamers and the proximity ligation assay for the detection of cell surface antigens / Supriya S. Pai and Andrew D. Ellington -- In vitro selection of protein-binding DNA aptamers as ligands for biosensing applications / Naveen K. Navani, Wing Ki Mok, and Yingfu Li -- Pt. V. Protein and DNA preparation. Immobilization of biomolecules onto silica and silica-based surfaces for use in planar array biosensors / Lisa C. Shriver-Lake, Paul T. Charles, and Chris R. Taitt -- Rapid DNA amplification using a battery-powered thin-film resistive thermocycler / Keith E. Herold ... [et al.].
  • Biotransport 2011, Springer
  • Bone tissue engineering 2005, CRCnetBASE
  • Calcium orthophosphates 2012, CRCnetBASE
  • The biomedical engineering senior capstone design course is probably the most important course taken by undergraduate biomedical engineering students. It provides them with the opportunity to apply what they have learned in previous years, develop their communication, teamwork, project management,and design skills,and learn about the product development process. It prepares students for professional practice and serves as a preview of what it will be like to work as a biomedical engineer.
  • Carbon nanotubes 2008, CRCnetBASE
  • Cell line development 2009, Springer
    Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This book deals with the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity and improve cell function.
  • Chitosan-based hydrogels 2012, CRCnetBASE
  • This book represents the first in a two-volume set on biological rhythms. This volume focuses on supporting the claim that biological rhythms are universal and essential characteristics of living organisms, critical for proper functioning of any living system. The author begins by examining the potential reasons for the evolution of biological rhythms: (1) the need for complex, goal-oriented devices to control the timing of their activities; (2) the inherent tendency of feedback control systems to oscillate; and (3) the existence of stable and powerful geophysical cycles to which all organisms must adapt. To investigate the second reason, the author enlists the help of biomedical engineering students to develop mathematical models of various biological systems. One such model involves a typical endocrine feedback system. By adjusting various model parameters, it was found that creating a oscillation in any component of the model generated a rhythmic cascade that made the entire system oscillate. This same approach was used to show how daily light/dark cycles could cascade rhythmic patterns throughout ecosystems and within organisms.
  • Colloids in drug delivery 2010, CRCnetBASE
    Surfactants and block copolymers in drug delivery / Ambikanandan Misra ... [et al.] -- Application of colloidal properties in drug delivery / Swarnlata Saraf -- Polymeric nanocapsules for drug delivery : an overview / Sílvia S. Guterres ... [et al.] -- Poly(alkyl cyanoacrylate) nanoparticles for drug delivery and vaccine development / Anja Graf, Karen Krauel-Göllner, Thomas Rades -- Stimuli-sensitive polymer gels for dermal and transdermal drug delivery and their application in the development of smart textile materials / Witold Musial and Vanja Kokol -- Micelles : the multifunctional nanocarrier for colloidal drug delivery / Chandana Mohanty, Sarbari Acharya, and Sanjeeb K. Sahoo -- Multiple emulsions : an overview and pharmaceutical applications / Jatin Khurana, Somnath Singh, and Alekha K. Dash -- Pharmaceutical and biotechnological applications of multiple emulsions / Rita Cortesi and Elisabetta Esposito -- Nanoemulsions as drug delivery systems / Figen Tirnaksiz, Seyda Akkus, and Nevin Celebi -- Microemulsion systems : application in delivery of poorly soluble drugs / Ljiljana Djekic and Marija Primorac -- Diclofenac solubilization in mixed nonionic surfactants microemulsions / Monzer Fanun -- Self-emulsifying drug delivery systems / D. P. Maurya, Yasmin Sultana, and M. Abul Kalam -- Liquid crystals and their application in the field of drug delivery / Rakesh Patel and Tanmay N. Patel -- Liquid crystalline nanoparticles as drug nanocarriers / Anan Yaghmur and Michael Rappolt -- Niosomal delivery system for macromolecular drugs / Yongzhuo Huang, Faquan Yu, and Wenquan Liang -- A new class of mesoscopic aggregates as a novel drug delivery system / Federico Bordi, Cesare Cametti, and Simona Sennato -- Liposomes and biomacromolecules : effects of preparation protocol on in vitro activity / Paola Luciani, Debora Berti, and Piero Baglioni -- Colloidal nanocarrier systems as a tool for improving antimycobacterial and antitumor activities and reducing the toxicity of usnic acid / N. S. Santos-Magalhães ... [et al.] -- Dendrimers in drug delivery / Hu Yang -- Microsphere : a novel drug delivery system / Abdus Samad ... [et al.] -- Colloids in aerosol drug delivery system / Nazrul Islam -- Respiratory aerosol dynamics with applications to pharmaceutical drug delivery / Jinxiang Xi, P. Worth Longest, and Paula J. Anderson -- Colloidal carriers for drug delivery in dental tissue engineering / Nader Kalaji, Nida Sheibat-Othman, and Hatem Fessi -- Classification and application of colloidal drug delivery systems : passive or active tumor targeting / H. Yesim Karasulu, Burcak Karaca, and Ercüment Karasulu -- Nanocarriers for imaging applications / Vandana Patravale and Medha Joshi.
  • Combination products 2008, CRCnetBASE
    Overview of combination products -- Ensuring successful combination product development -- Overview of FDA and other regulatory agency expectations -- Resource requirements -- Manufacturing of combination products -- Challenges and pitfalls to avoid with combination products -- Postlaunch compliance requirements -- Agency audits and challenges.
  • Biomedical robotics and biomechatronics -- Complex virtual technology in medicine -- Information and communication technology in medicine -- Complex technology in rehabilitation -- Cognitive neuroscience and technology -- Complex bioinformatics.
  • Recent advances in development of sequencing technology has resulted in a deluge of genomic data. In order to make sense of this data, there is an urgent need for algorithms for data processing and quantitative reasoning. An emerging in silico approach, called computational genomic signatures, addresses this need by representing global species-specific features of genomes using simple mathematical models. This text introduces the general concept of computational genomic signatures, and it reviews some of the DNA sequence models which can be used as computational genomic signatures. The text takes the position that a practical computational genomic signature consists of both a model and a measure for computing the distance or similarity between models. Therefore, a discussion of sequence similarity/distance measurement in the context of computational genomic signatures is presented. The remainder of the text covers various applications of computational genomic signatures in the areas of metagenomics, phylogenetics and the detection of horizontal gene transfer.
  • pt. B, 2009 ScienceDirect
    pt. C, 2011 ScienceDirect
  • Conductive polymers as organic nanometals -- Conducting polymer fibre for smart fabric and interactive textile applications -- Inkjet printing and patterning of PEDOT-PSS -- Printing organic electronics on flexible substrates -- Light emitting polymers -- Organic electro-optic materials -- Conjugated polymer electronics -- Electrical bistable polymer films and their applications in memory devices -- Electroactive polymers for batteries and supercapacitors -- Conjugated polymer based photovoltaic devices -- Biomedical applications of ICPs -- Biosensors based on conducting electroactive polymers -- Optical biosensors based on conjugated polymers -- Conducting polymers for MEMS and other micro-devices -- Corrosion protection using conducting polymers -- Artificial muscles.
  • Cryocoolers 13 2005, Springer
  • Deformable models 2007, Springer
  • Dental pulp stem cells 2013, Springer
    Dental Evolution -- Tooth development -- Dental Pulp is a Connective Tissue -- Dental Pulp Stem Cells (DPSC) -- Isolation methods of DPSC -- Characterization of DPSC -- Reprogramming of DPSC to induced pluripotent stem cells (iPSC) -- Immunomodulatory effects of DPSC -- Dental Pulp is a Complex Adaptive System.
  • Fundus images of the retina are color images of the eye taken by specially designed digital cameras. Ophthalmologists rely on fundus images to diagnose various diseases that affect the eye, such as diabetic retinopathy and retinopathy of prematurity. A crucial preliminary step in the analysis of retinal images is the identification and localization of important anatomical structures, such as the optic nerve head (ONH), the macula, and the major vascular arcades. Identification of the ONH is an important initial step in the detection and analysis of the anatomical structures and pathological features in the retina. Different types of retinal pathology may be detected and analyzed via the application of appropriately designed techniques of digital image processing and pattern recognition. Computer-aided analysis of retinal images has the potential to facilitate quantitative and objective analysis of retinal lesions and abnormalities. Accurate identification and localization of retinal features and lesions could contribute to improved diagnosis, treatment, and management of retinopathy.
  • Includes biomedical and health applications, biomedical sensing, cure and health monitoring, drug deliversy systems, health monitoring using wave dynamics, polymers, biotechnology and medical applications.
  • Epidermal cells 2004, Springer Protocols
    Analysis of connexin 43 expression on keratinocytes using flow cytometry / Maja Matic ... [et al.] -- MMP-9 and TIMP-1 assays in keratinocyte cultures / Takashi Kobayashi -- Characterization of epithelial cells in the hair follicle with S100 proteins / Kenji Kizawa and Mayumi Ito -- Immunoelectron microscopic analysis of cornified cell envelopes and antigen retrieval / Akemi Ishida-Yamamoto -- Cell kinetic analysis in artificial skin using immunochemical methods / Andrea Casasco ... [et al.] -- Proliferation, differentiation, and inflammation in normal and hyperproliferative skin using multiparameter flow cytometry / Piet E.J. van Erp -- Fluorimetric DNA assay of cell number / William R. Otto -- Keratinocyte transient transfections / Anthony M. Flores and Brian J. Aneskievich -- Tetracycline-regulated gene expression in epidermal keratinocytes / Richard B. Presland and Philip Fleckman -- Gene targeting by oligonucleotides in keratinocytes / Olga Igoucheva and Kyonggeun Yoon --Epidermis-targeted gene transfer using in vivo electroporation / Hiroki Maruyama, Jun-Ichi Miyazaki and Fumitake Gejyo -- Gene and stem cell therapy of the hair follicle / Robert M. Hoffman.Isolation, characterization, and culture of epithelial stem cells / Jackie R. Bickenbach -- Keratin 19 as a stem cell marker in vivo and in vitro / Danielle Larouche ... [et al.] -- Immunolocalization in the epidermis / Tammy-Claire Troy ... [et al.] -- Epidermal cell analysis by RT-PCR / Tammy-Claire Troy ... [et al.] -- Whole-mount assays for gene induction and barrier formation in the developing epidermis / Carolyn Byrne and Matthew J. Hardman -- Analysis of early epidermal development in zebrafish / Ashley E. Webb and David Kimelman -- Analysis of E2F factors during epidermal differentiation / Wing Y. Chang and Lina Dagnino -- Analysis of HOX homeodomain proteins and gene transcripts in the epidermis / László G. Kömüves and Corey Largman -- Apoptosis in the epidermis / Kiyofumi Yamanishi, Chun-Shen Shen and Hitoshi Mizutani -- Fate of desmosomal proteins in apoptotic epidermal cells / Jörg Weiske and Otmar Huber --Primary mouse keratinocyte culture / Annalisa Pirrone, Barbara Hager, and Philip Fleckman -- Serial cultivation of primary adult murine keratinocytes / Richard P. Redvers and Pritinder Kaur -- Keratinocyte culture in the absence of substrate attachment / Monika Jost and Ulrich Rodeck -- Application of genetically modified feeder cells for culture of keratinocytes / Takashi Kameda and Toshihiro Sugiyama -- Organ culture of developing mouse skin and its application for molecular mechanistic studies of morphogenesis / Mariko Kashiwaga and Nam-ho Huh -- Experimental models to analyze differentiation functions of cultured keratinocytes in vitro and in vivo / Nicole Maas-Szabowski, Norbert E. Fusenig, and Hans-Jürgen Stark -- In vitro fabrication of engineered human skin / Alexander Margulis, Weitian Zhang and Jonathan A. Garlick -- In vivo labeling and analysis of epidermal stem cells / Wei-Yang Wu and Rebecca J. Morris -- Method for the harvest and assay of in vitro clonogenic keratinocytes stem cells from mice / Wei-Yang Wu and Rebecca J. Morris -- FACS enrichment of human keratinocyte stem cells / Amy Li and Pritinder Kaur --Promoter analysis in the human SPRR gene family / David F. Fischer and Claude Backendorf -- Stable integration of large PAC contructs in keratinocytes / Sarah H. Williams and Alain Hovnanian -- Targeted somatic mutagenesis in the mouse epidermis / Daniel Metzger, Mei Li, and Pierre Chambon -- Methods to study protein-protein interactions / Jin-Jun Meng ... [et al.] -- Isolation of recombinant phage-displayed antibodies recognizing skin keratinocytes / Kim Bak Jensen and Peter Kristensen -- Analysis of tissue-specific DNA methylation during development / Jun Ohgane, Naka Hattori and Kunio Shiota -- Serial analysis of gene expression in human keratinocytes and the epidermis / Bastiaan J.H. Jansen ... [et al.] -- Methods for gene expression profiling in dermatology research using DermArray® nylon filter DNA microarrays / Richard L. Davis Jr. ... [et al.] -- Two-photon fluorescence imaging and reactive oxygen species detection within the epidermis / Kerry M. Hanson and Robert M. Clegg -- In vivo transplantation of engineered human skin / Shari Greenberg, Alexander Margulis and Jonathan A. Garlick --
  • Ergonomics and psychology 2008, CRCnetBASE
    Ecological ergonomics / Marvin J. Dainoff -- Integrating cognitive and digital human models for virtual product design / Daniel W. Carruth and Vincent G. Duffy -- Time study during vocational training / Gregory Z. Bedny and Waldemar Karwowski -- The laws of ergonomics applied to design and testing of workstations / V.F. Venda, V.K. Kalin, and A.Y. Trofimov -- Day-to-day monitoring of an operator's functional state and fitness-for-work : a psychophysiological and engineering approach / Oleksandr Burov -- Identification of mental modules ; Identification of neural modules / Saul Sternberg -- The new interface of brain, mind, and machine : will the emergent whole be greater than the sum of the parts? / Chris Berka ... [et al.] -- The interaction of sleep and memory / Jeffrey M. Ellenbogen -- Attention, selection for action, error processing, and safety / Magdalena Fafrowicz and Tadeusz Marek -- Activity theory : comparative analysis of Eastern and Western approaches / Waldemar Karwowski, Gregory Z. Bedney, and Olexiy Y. Chebykin -- Discourse in activity / Harry Daniels -- Movements of the cane prior to locomotion judgments : the informer fallacy and the training fallacy versus the role of exploration / Gregory Burton and Jennifer Cyr -- Emotional intelligence : a novel approach to operationalizing the construct / E.L. Nosenko -- Emotional regulation of the learning process / Olexiy Y. Chebykin and S.D. Maksymenko -- Emotional resources of the professional trainer / G.V. Lozhkin -- Good judgment : the intersection of intelligence and personality / Robert Hogan, Joyce Hogan and Paul Barrett -- Relational self in action : relationships and behavior / Susan E. Cross and Kari A. Terzino.
  • Posture and movement -- Information and operation -- Environmental factors -- Work organization jobs and tasks -- The ergonomic approach -- Sources of additional information.
  • Introduction to stem cells -- Basic biology/mechanisms -- Tissue and organ development -- Methods -- Applications -- Regulation and ethics.
  • Increasingly, biomedical scientists and engineers are involved in projects, design, or research and development that involve humans or animals. The book presents general concepts on professionalism and the regulation of the profession of engineering, including a discussion on what is ethics and moral conduct, ethical theories and the codes of ethics that are most relevant for engineers. An ethical decision-making process is suggested. Other issues such as conflicts of interest, plagiarism, intellectual property, confidentiality, privacy, fraud, and corruption are presented. General guidelines, the process for obtaining ethics approval from ethics Review Boards,and the importance of obtaining informed consent from volunteers recruited for studies are presented. A discussion on research with animals is included. Ethical dilemmas focus on reproductive technologies, stem cells, cloning, genetic testing, and designer babies. The book includes a discussion on ethics and the technologies of body enhancement and of regeneration. The importance of assessing the impact of technology on people, society, and on our planet is stressed. Particular attention is given to nanotechnologies, the environment, and issues that pertain to developing countries. Ideas on gender, culture, and ethics focus on how research and access to medical services have, at times, been discriminatory towards women. The cultural aspects focus on organ transplantation in Japan, and a case study of an Aboriginal child in Canada; both examples show the impact that culture can have on how care is provided or accepted. The final section of the book discusses data collection and analysis and offers a guideline for honest reporting of results, avoiding fraud, or unethical approaches. The appendix presents a few case studies where fraud and/or unethical research have occurred.
  • Fractal analysis is useful in digital image processing for the characterization of shape roughness and gray-scale texture or complexity. Breast masses present shape and gray-scale characteristics in mammograms that vary between benign masses and malignant tumors. This book demonstrates the use of fractal analysis to classify breast masses as benign masses or malignant tumors based on the irregularity exhibited in their contours and the gray-scale variability exhibited in their mammographic images. A few different approaches are described to estimate the fractal dimension (FD) of the contour of a mass, including the ruler method, box-counting method, and the power spectral analysis (PSA) method. Procedures are also described for the estimation of the FD of the gray-scale image of a mass using the blanket method and the PSA method.
  • From brains to systems 2011, Springer
    Introduction: From Brains to the Machines of the Future / Ricardo Sanz, Carlos Hernández and Jaime Gómez-Ramirez -- Emergent Feature Sensitivity in a Model of the Auditory Thalamocortical System / Martin Coath, Robert Mill, Susan L. Denham and Thomas Wennekers -- STDP Pattern Onset Learning Depends on Background Activity / James Humble, Steve Furber, Susan L. Denham and Thomas Wennekers -- Emergence of Small-World Structure in Networks of Spiking Neurons Through STDP Plasticity / Gleb Basalyga, Pablo M. Gleiser and Thomas Wennekers -- Coupling BCM and Neural Fields for the Emergence of Self-organization Consensus / Mathieu Lefort, Yann Boniface and Bernard Girau -- Alpha and Theta Rhythm Abnormality in Alzheimer's Disease: A Study Using a Computational Model / Basabdatta Sen Bhattacharya, Damien Coyle and Liam P. Maguire -- Oscillatory Neural Network for Image Segmentation with Biased Competition for Attention / Tapani Raiko and Harri Valpola -- Internal Simulation of Perceptions and Actions / Magnus Johnsson and David Gil -- Building Neurocognitive Networks with a Distributed Functional Architecture / Marmaduke Woodman, Dionysios Perdikis, Ajay S. Pillai, Silke Dodel and Raoul Huys, et al. -- Reverse Engineering for Biologically Inspired Cognitive Architectures: A Critical Analysis / Andreas Schierwagen -- Competition in High Dimensional Spaces Using a Sparse Approximation of Neural Fields / Jean-Charles Quinton, Bernard Girau and Mathieu Lefort -- Informational Theories of Consciousness: A Review and Extension / Igor Aleksander and David Gamez -- Hippocampal Categories: A Mathematical Foundation for Navigation and Memory / Jaime Gómez-Ramirez and Ricardo Sanz -- The Role of Feedback in a Hierarchical Model of Object Perception / Salvador Dura-Bernal, Thomas Wennekers and Susan L. Denham -- Machine Free Will: Is Free Will a Necessary Ingredient of Machine Consciousness? / Riccardo Manzotti -- Natural Evolution of Neural Support Vector Machines / Magnus Jändel -- Self-conscious Robotic System Design Process - From Analysis to Implementation / Antonio Chella, Massimo Cossentino and Valeria Seidita -- Simulating Visual Qualia in the CERA-CRANIUM Cognitive Architecture / Raúl Arrabales, Agapito Ledezma and Araceli Sanchis -- The Ouroboros Model, Selected Facets / Knud Thomsen.
  • 1. Introduction -- 2. Carpal Tunnel Syndrome, Electroneurography, Electromyography, and Statistics -- 3. Tremor, Polymyography, and Spectral Analysis -- 4. Epilepsia, Electroencephalography, Filtering, and Feature Extraction -- 5. Multiple Sclerosis, Evoked Potentials, and Enhancing Signal-to-Noise Ratio -- 6. Cortical Myoclonus, EEG-EMG, Back-Averaging, and Coherence Analysis -- 7. Psychogenic Movement Disorders, Bereitschaftspotential, and Event-Related Potentials -- 8. Brain Tumor, Preoperative Function Localization, and Source Localization -- 9. Neuromuscular Diseases, Ultrasound, and Image Analysis -- 10. Cerebrovascular Disease, Ultrasound, and Hemodynamical Flow Parameters -- 11. Spinal Dysfunction, Transcranial Magnetic Stimulation, and Motor Evoked Potentials.
  • Transport processes represents important life sustaining elements in all humans. These include mass transfer processes, including gas exchange in the lungs, transport across capillaries and alveoli, transport across the kidneys, and transport across cell membranes. These mass transfer processes affect how oxygen and carbon dioxide are exchanged in your bloodstream, how metabolic waste products are removed from your blood, how nutrients are transported to tissues, and how all cells function throughout the body. A discussion of kidney dialysis and gas exchange mechanisms is included. Another element in biomedical transport processes is that of momentum transport and fluid flow. This describes how blood is propelled from the heart and throughout the cardiovascular system, how blood elements affect the body, including gas exchange, infection control, clotting of blood, and blood flow resistance, which affects cardiac work. A discussion of the measurement of the blood resistance to flow (viscosity), blood flow, and pressure is also included. A third element in transport processes in the human body is that of heat transfer, including heat transfer inside the body towards the periphery as well as heat transfer from the body to the environment. A discussion of temperature measurements and body protection in extreme heat conditions is also included.
  • Introduction -- 1. Environmental and Occupationally Encountered Electromagnetic Fields / Kjell Hansson Mild and Ben Greenebaum -- 2. Endogenous Electric Fields in Animals / Richard Nuccitelli -- 3. Dielectric Properties of Biological Materials / Camelia Gabriel -- 4. Magnetic Properties of Biological Material / Jon Dobson -- 5. Interaction of Direct Current and Extremely Low-Frequency / Electric Fields with Biological Materials and Systems / Frank S. Barnes -- 6. Magnetic Field Effects on Free Radical Reactions in Biology / Stefan Engström -- 7. Signals, Noise, and Thresholds / James C. Weaver and Martin Bier -- 8. Biological Effects of Static Magnetic Fields / Shoogo Ueno and Tsukasa Shigemitsu -- 9. The Ion Cyclotron Resonance Hypothesis / A.R. Liboff -- 10. Computational Methods for Predicting Field Intensity and Temperature Change / James C. Lin and Paolo Bernardi -- 11. Experimental EMF Exposure Assessment / Sven Kühn and Niels Kuster -- 12. Electromagnetic Imaging of Biological Systems / William T. Joines, Qing H. Liu, and Gary Ybarra.

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