Books by Subject
- 2005-06 OvidBartlett, John G.
- 2010 ClinicalKeyFinch, R. G.1. Historical introduction -- 2. Modes of action -- 3. The problem of resistance -- 4. Pharmacodynamics of anti-infective agents: target delineation and susceptibility breakpoint selection -- 5. Antimicrobial agents and the kidneys -- 6. Drug interactions involving anti-infective agents -- 7. Antibiotics and the immune system -- 8. General principles of antimicrobial chemotherapy -- 9. Laboratory control of antimicrobial therapy -- 10. Principles of chemop rophylaxis -- 11. Antibiotic policies -- 12. Aminoglycosides and aminocyclitols -- 13. β-Lactam antibiotics : cephalosporins -- 14. β-Lactam antibiotics: penicillins -- 15. Other β-lactam antibiotics -- 16. Chloramphenicol and thiamphenicol -- 17. Diaminopyrimidines -- 18. Fosfomycin and fosmidomycin -- 19. Fusidanes -- 20. Glycopeptides -- 21. Lincosamides -- 22. Macrolides -- 23. Mupirocin -- 24. Nitroimidazoles -- 25. Oxazolidinones -- 26. Quinolones -- 27. Rifamycins -- 28. Streptogramins -- 29. Sulfonamides -- 30. Tetracyclines -- 31. Miscellaneous antibacterial agents -- 32. Antifungal agents -- 33. Antimycobacterial agents -- 34. Anthelmintics -- 35. Antiprotozoal agents -- 36. Antiretroviral agents -- 37. Other antiviral agents -- 38. Sepsis -- 39. Abdominal and other surgical infections -- 40. Infections associated with neutropenia and transplantation -- 41. Infections in intensive care patients -- 42. Infections associated with implanted medical devices -- 43. Antiretroviral therapy for HIV -- 44. Infections of the upper respiratory tract -- 45. Infections of the lower respiratory tract -- 46. Endocarditis -- 47. Infections of the gastrointestinal tract -- 48. Hepatitis -- 49. Skin and soft-tissue infections -- 50. Bacterial infections of the central nervous system -- 51. Viral infections of the central nervous system -- 52. Bone and joint infections -- 53. Infections of the eye -- 54. Urinary tract infections -- 55. Infections in pregnancy -- 56. Sexually transmitted diseases -- 57. Leprosy -- 58. Tuberculosis and other mycobacterial infections -- 59. Superficial and mucocutaneous mycoses -- 60. Systemic fungal infections -- 61. Zoonoses -- 62. Malaria -- 63. Other protozoal infections -- 64. Helminthic infections.
- 2012 SpringerDougherty, Thomas J.; Pucci, Michael J.
- 2011 SpringerGould, Ian M.; Meer, J. W. M. van der.
- 2007 SpringerGould, Ian M.; Meer, J. W. M. van der.
- 2012 SpringerCoates, Anthony R.M.Introduction to antibiotic resistance/ Richard Bax, David Griffin -- The origins of antibiotic resistance/ Gerard D. Wright -- Surveillance programmes and antibiotic resistance: worldwide and regional monitoring of antibiotic resistance trends/ Stephen Hawser -- Current and future challenges in the development of antimicrobial agents/ Robert P. Rennie -- The role of the outer membrane of gram-negative bacteria in antibiotic resistance: Ajax' shield or Achilles' heel?/ Malcolm G.P. Page -- Prevention of drug resistance by combined drug treatment of tuberculosis/ Denis A. Mitchison -- Nonmultiplying bacteria are profoundly tolerant to antibiotics / Yanmin Hu, Anthony Coates -- Persister cells: molecular mechanisms related to antibiotic tolerance / Kim Lewis -- Antimicrobial textiles / J. Vaun McArthur, R.C. Tuckfield, C. Baker-Austin -- Efflux: how bacteria use pumps to control their microenvironment / E. David G. McIntosh -- Antibiotics in phase II and III clinical trials / Anthony R.M. Coates, Gerry Halls.
- Antibiotic resistance : because of overuse and misuse, some antibiotics are losing effectiveness against highly resistant bacteria.2015This brief provides an overview of antibiotic resistance, including a summary of its current impact, the factors that contribute to its spread, and the policy recommendations put in place by federal and global public health agencies. It also reviews the debate around the regulation of antibiotic use in agriculture and examines new developments in policy and research associated with multidrug-resistant bacterial diseases and their underlying causes.
- Gallagher, Jason C.; MacDougall, Conan.Part 1. Considerations with antibiotic therapy -- Part 2. Antibacterial drugs -- Part 3. Antimycobacterial drugs -- Part 4. Antifungal drugs -- Part 5. Antiviral drugs -- Part 6. Antiparasitic Drugs -- Appendix 1. Selected normal human flora -- Appendix 2. Spectrum of activity -- Appendix 3. Empiric regimens for common infections -- Index.
- 2010 SpringerShlaes, David M.
- Includes information on antimicrobial therapy and alternative therapy when the drug of choice cannot be given. The resource delivers information via review articles, capsule summaries, mini-reviews, and a guided PubMed search to pick up post-publication research.
- 2007Davey, Peter; Finch, R. G.; Greenwood, David; Wilcox, Mark.PrintStatus: Not Checked OutLane Catalog Record
- 2012 OvidFinch, R. G.Pt. 1. General properties of antimicrobial agents -- Pt. 2. Resistance to antimicrobial agents -- Pt. 3. General principles of usage of antimicrobial agents -- Pt. 4. Therapeutic use of antimicrobial agents.
- 2014 SpringerGonzález Villa, Tomás; Veiga-Crespo, Patricia.Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.
- 2006 SpringerShafer, William M.Paneth cell [alpha]-defensin synthesis and function / A.J. Ouellette -- Immunomodulatory properties of defensins and cathelicidins / D.M.E. Bowdish, D.J. Davidson, and R.E.W. Hancock -- Host antimicrobial defence peptides in human disease / B. Agerberth and G.H. Guðmundsson -- Antimicrobial peptides: an essential component of the skin defensive barrier / M.H. Braff and R.L. Gallo -- Antimicrobial peptides versus invasive infections / M.R. Yeaman and A.S. Bayer -- Antimicrobial peptides in the airway / D.M. Laube ... [et al.] -- Hepcidin: a peptide hormone at the interface of innate immunity and iron metabolism / T. Ganz -- Innate host defense of human vaginal and cervical mucosae / A.M. Cole -- Molecular mechanisms of bacterial resistance to antimicrobial peptides / D. Kraus and A. Peschel -- Bacterial evasion of antimicrobial peptides by biofilm formation / M. Otto.Also available: Print – 2006
- 2014 WHOThis report examines, for the first time, the current status of surveillance and information on antimicrobial resistance (AMR) at country level worldwide, with particularly attention to antibacterial resistance.Also available: Print – 2014
- 2014 SpringerGenilloud, Olga; Marinelli, Flavia.Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the "arms race" with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed.
- Anti-tuberculosis drug resistance in the world : fourth global report : the World Health Organization/International Union Against Tuberculosis and Lung Disease (WHO/UNION) Global Project on Anti-Tuberculosis Drug Resistance Surveillance, 2002-20072008 WHOWright, Abigail; Zignol, Matteo.Also available: Print – 2008
- 2008 CRCnetBASELewis, Kim; Salyers, Abigail A.; Taber, Harry; Wax, Richard G.Microbial drug resistance: a historical perspective / William C. Summers -- Ecology of antibiotic resistance genes / Abigail A. Salyers, Nadja Shoemaker, and David Schlesinger -- Global response systems that confer resistance / Paul F. Miller and Philip N. Rather -- Multidrug efflux pumps: structure, mechanism, and inhibition / Olga Lomovskaya ... [et al.] -- Mechanisms of aminoglycoside antibiotic resistance / Gerard D. Wright -- Resistance to [beta]-lactam antibiotics mediated by [beta]-lactamases : structure, mechanism, and evolution / Jooyoung Cha, Lakshmi P. Kotra, and Shahriar Mobashery -- Target modification as a mechanism of antimicrobial resistance / David C. Hooper -- Antibiotic permeability / Harry Taber -- Genetic methods for detecting bacterial resistance genes / Ad C. Fluit -- Evolution and epidemiology of antibiotic-resistant pneumococci / Christopher Gerard Dowson and Krzysztof Trzcinski -- Antimicrobial resistance in the enterococcus / George M. Eliopoulos -- Methicillin resistance in staphylococcus aureus / Keeta S. Gilmore, Michael S. Gilmore, and Daniel F. Sahm -- Mechanism of drug resistance in mycobacterium tuberculosis / Alex S. Pym and Stewart T. Cole -- Antibiotic resistance in enterobacteria / Nafsika H. Georgopapadakou -- Resistance as a worldwide problem / Paul Shears -- Public health responses to antimicrobial resistance in outpatient and inpatient settings / Cindy R. Friedman and Arjun Srinivasan -- Antibacterial drug discovery in the 21st century / Steven J. Projan.Also available: Print – 2008
- 2005 SpringerFranklin, T. J.; Franklin, T. J.; Snow, G. A.
- 2014 CRCnetBASESayen, S. M. Abu.Front Cover; About the Editor; Contents; Acknowledgment and How to Cite; List of Contributors; Introduction; Chapter 1: Potential Novel Therapeutic Strategies in Cystic Fibrosis: Antimicrobial and Anti-Biofilm Activity of Natural and Designed [alpha]-Helical Peptides Against Staphylococcus aureus, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia; Chapter 2: Dispersal of Biofilms by Secreted, Matrix Degrading, Bacterial DNase. 1. Potential novel therapeutic strategies in cystic fibrosis : antimicrobial and anti-biofilm activity of natural and designed A-helical peptides against staphylococcus aureus, pseudomonas aeruginosa, and stenotrophomonas maltophilia / Arianna Pompilio, Valentina Crocetta, Marco Scocchi, Stefano Pomponio, Valentina Di Vincenzo, Mario Mardirossian, Giovanni Gherardi, Ersilia Fiscarelli, Giordano Dicuonzo, Renato Gennaro, and Giovanni Di Bonaventura -- 2. Dispersal of biofilms by Secreted, Matrix Degrading, Bacterial DNase / Reindert Nijland, Michael J. Hall, and J. Grant Burgess -- 3. The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-n-acetylglucosamine (PNAG) production in escherichia coli C / Thomas Carzaniga, Davide Antoniani, Gianni Deh, ̣Federica Briani, and Paolo Landini -- 4. Comparative proteomic analysis of streptococcus suis biofilms and planktonic cells that identified biofilm infection-related immunogenic proteins / Yang Wang, Li Yi, Zongfu Wu, Jing Shao, Guangjin Liu, Hongjie Fan, Wei Zhang, and Chengping Lu -- 5. Anti-biofilm activity of an exopolysaccharide from a sponge-associated strain of bacillus licheniformis / S.M. Abu Sayem, Emiliano Manzo, Letizia Ciavatta, Annabella Tramice, Angela Cordone, Anna Zanfardino, Maurilio De Felice, and Mario Varcamonti -- 6. Osteopontin reduces biofilm formation in a multi-species model of dental biofilm / Sebastian Schlafer, Merete K. Raarup, Peter L. Wejse, Bente Nyvad, Brigitte M. Std̃ler, Duncan S. Sutherland, Henrik Birkedal, and Rikke L. Meyer -- 7. Impairment of the bacterial biofilm stability by triclosan / Helen V. Lubarsky, Sabine U. Gerbersdorf, Cďric Hubas, Sebastian Behrens, Francesco Ricciardi, and David M. Paterson -- 8. Antimicrobial pressure of ciprofloxacin and gentamicin on biofilm development by an endoscope-isolated pseudomonas aeruginosa / Idalina Machado, Joana Graȧ, Hľder Lopes, Susana Lopes, and Maria O. Pereira -- 9. Inhibition of staphylococcus epidermidis biofilm formation by traditional Thai herbal recipes used for wound treatment / S. Chusri, K. Sompetch, S. Mukdee, S. Jansrisewangwong, T. Srichai, K. Maneenoon, S. Limsuwan, and S.P. Voravuthikunchai -- 10. In vitro assessment of shiitake mushroom (lentinula edodes) extract for its antigingivitis activity / Lena Ciric, Anna Tymon, Egija Zaura, Peter Lingstrm̲, Monica Stauder, Adele Papetti, Caterina Signoretto, Jonathan Pratten, Michael Wilson, and David Spratt -- 11. Antimicrobial, antimycobacterial and antibiofilm properties of couroupita guianensis aubl. fruit extract / Naif Abdullah Al-Dhabi, Chandrasekar Balachandran, Michael Karunai Raj, Veeramuthu Duraipandiyan, Chinnasamy Muthukumar, Savarimuthu Ignacimuthu, Inshad Ali Khan, and Vikrant Singh Rajput -- 12. Fur is a repressor of biofilm formation in yersinia pestis / Fengjun Sun, He Gao, Yiquan Zhang, Li Wang, Nan Fang, Yafang Tan, Zhaobiao Guo, Peiyuan Xia, Dongsheng Zhou, and Ruifu Yang -- 13. Hsp90 governs dispersion and drug resistance of fungal biofilms / Nicole Robbins, Priya Uppuluri, Jeniel Nett, Ranjith Rajendran, Gordon Ramage, Jose L. Lopez-Ribot, David Andes, and Leah E. Cowen -- 14. Candida biofilms and the host : models and new concepts for eradication / Hľn̈e Tournu and Patrick Van Dijck -- 15. Innovative strategies to overcome biofilm resistance / Aleksandra Taraszkiewicz, Grzegorz Fila, Mariusz Grinholc, and Joanna Nakonieczna.
- 2006 CRCnetBASEFinch, R. G.; Pace, John L.; Rupp, Mark E.Microbial biofilms / Xiuping Jiang and John L. Pace -- Economic impact of biofilms on treatment costs / John G. Thomas, Isaiah Litton, and Harald Rinde -- Biofilm-related indwelling medical device infections / Matthew K. Schinabeck and Mahmoud A. Ghannoum -- Medical device composition and biological secretion influences on biofilm formation / Sean P. Gorman and David S. Jones -- Role of biofilms in infections caused by Escherichia coli / Grégory Jubelin, Corinne Dorel, and Philippe Lejeune -- Staphylococcus aureus biofilms / Julie M. Higashi and Paul M. Sullam -- Coagulase-negative staphylococci / Dietrich Mach ... [et al.] -- Pseudomonas aeruginosa biofilm infections in cystic fibrosis / Andrea Smiley and Daniel J. Hassett -- Candida / Stephen Hawser and Khalid Islam -- Current perspectives on the regulation of the ica operon and biofilm formation in Staphylococcus epidermidis / Paul D. Fey and Luke D. Handke -- Cell-to-cell communication in bacteria / Kenneth D. Tucker and Luciano Passador -- Persisters: specialized cells responsible for biofilm tolerance to antimicrobial agents / Kim Lewis ... [et al.] -- Minimal biofilm eradication concentration (MBEC) assay: susceptibility testing for biofilms / Howard Ceri ... [et al.] -- Environmental cues regulate virulence and biofilm formation / John L. Pace and Steven M. Frey -- In vivo models for the study of biomaterial-associated infection by biofilm-forming staphylococci / Luke D. Handke and Mark E. Rupp -- Host response to biofilms / Susan Meier-Davis -- Pharmacodynamics and the treatment of IMD-related infections / Roger Finch and Sarah Gander -- Protein synthesis inhibitors, fluoroquinolones, and rifampin for biofilm infections / Steven L. Barriere -- [beta][beta]-lactams for the treatment of biofilm-associated infections / Ingrid L. Dodge, Karen Joy Shaw, and Karen Bush -- Glycopeptide antibacterials and the treatment of biofilm-related infections / John L. Pace, Roasaire Verna, and Jan Verhoef -- Antibiotic resistance in biofilms / Nafsika H. Georgopapadakou -- Treatment protocols for infections of vascular catheters / Russell E. Lewis and Issam I Raad -- Treatment protocols for bacterial endocarditis and infection of electrophysiologic cardiac devices / Martin E. Stryjewski and G. Ralph Corey -- Treatment protocol of infections of orthopedic devices / Vera Antonios, Elie Berbari, and Douglas Osmon.
- 2014 CRCnetBASEGupta, Satya Prakash."Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), Human papilloma virus (HPV), Human herpes virus 8 (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV), Human immunodeficiency virus (HIV/AIDS), Oncolytic viruses. This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies"--Provided by publisher.
- 2012 SpringerFinberg, Robert W.; Guharoy, Roy.
- 2009 SpringerFrank, Uwe; Daschner, Franz; Tacconelli, Evelina.
- 2012 SpringerFrank, Uwe; Daschner, Franz; Tacconelli, Evelina.Classification of the Antibiotics -- Antibiotics Marketed in the EU -- Principles of Antibiotic Therapy -- The Most Common Errors in Antibiotic Therapy -- Important Infections and Their Microbiological Diagnosis -- Cooperation with Microbiologists -- Resistance of Major Clinical Pathogens -- The Most Frequent Pathogens- Choice of Antibiotics -- Antibiotics, Antimycotics: Spectrum- Dosage- Adverse Effects- Costs -- Antibiotic Therapy of the Principal Infections in Children and Adults -- Treatment of the Most Frequent Types of Bacterial Endocarditis -- Minimal Duration of Treatment for Bacterial Infections -- Failure of Antibiotic Therapy -- Fever of Unknown Origin: Differential Diagnosis -- Dosage of Antibiotics in Impaired Renal Function -- Antibiotic Therapy in Haemodialysis, Peritoneal Dialysis, and Continuous Haemofiltration -- Antibiotic Therapy During Pregnancy and Lactation -- Antibiotics in Liver Diseases -- Diffusion of Antibiotics in Cerebrospinal Fluid and in Cerebral Abscesses -- Local Antibiotics -- Prophylactic Antibiotic Therapy -- Physical Incompatibility of Antibiotics and Antimycotics in Infusion Solutions -- Useful Websites.
- 2012 SpringerBornstein, Gadi G.; Klakamp, Scott L.; Tabrizi, Mohammad A.1. Translational Strategies for Development of Antibody-Based Therapeutics: An Overview / Mohammad Tabrizi, Gadi Gazit Bornstein and Scott L. Klakamp -- 2. Discovery Process for Antibody-Based Therapeutics / Heather H. Shih -- 3. Technologies for the Generation of Human Antibodies / Ramesh R. Bhatt, John S. Haurum and C. Geoffrey Davis -- 4. Application of Antibody Engineering in the Development of Next Generation Antibody-Based Therapeutics / Randall J. Brezski and Juan Carlos Almagro -- 5. Biophysical Considerations for Development of Antibody-Based Therapeutics / Andrew W. Drake and Giuseppe A. Papalia -- 6. Considerations in Establishing Affinity Design Goals for Development of Antibody-Based Therapeutics / Mohammad Tabrizi -- 7. Bioanalytical Considerations for Development of Antibody-Based Therapeutics: Pharmacokinetics and Immunogenicity / Cherryl B. Funelas and Scott L. Klakamp -- 8. Preclinical Considerations for Development of Antibody-Based Therapeutics in Oncology / Gregory Landes and Kathleen Elias -- 9. Factors Impacting the Tumor Localization and Distribution of Antibody-Based Therapeutics in Oncology / David C. Blakey -- 10. Preclinical Safety Considerations for the Development of Antibody-Based Therapeutics / Lolke de Haan -- 11. Application of Pharmacokinetic/Pharmacodynamic Modeling in the Development of Antibody-Based Therapeutics / Donald E. Mager -- 12. Application of Population Pharmacokinetic-Pharmacodynamic Approaches in the Design of Translational Strategies for Development of Antibody-Based Therapeutics / Feng Jin -- 13. Translational Biomarkers: Essential Tools in Development of Antibody-Based Therapeutics / Mohammad A. Tabrizi and Cherryl B. Funelas -- 14. Translational Research in Alzheimer's Disease for Development of Antibody-Based Therapeutics / Eric C. Yuen, Enchi Liu and Gene G. Kinney -- 15. Considerations in Manufacturing Process Development for Antibody-Based Therapeutics / Paula C. Miller and Peiling Xu -- 16. Strategies for Development of Next Generation Antibody-Based Therapeutics / Mohammad Tabrizi and Gadi Gazit Bornstein -- 17. Immune Complex Therapies for Treatment of Immune Thrombocytopenia / Rong Deng and Joseph P. Balthasar -- 18. Application of Bioinformatics Principles for Target Evaluation / Anthony Carvalloza, Mohammad Fallahi and Sahba Tabrizifard -- 19. Concluding Remarks / Mohammad Tabrizi, Gadi Gazit Bornstein and Scott L. Klakamp.
- 2007 CRCnetBASEManivannan, Gurusamy.Perspectives on infection challenges and solutions / Manivannan -- Sisyphus in the microbial world revisited : global governance, antimicrobial strategies, and humanity's health / Fidler -- The need for safer and better microbiocides for infection control / Sattar, Springthorpe -- Microbiological concerns in non-sterile manufacturing / Farrington, Polarine -- New technologies in disinfection and infection control / Ramirez -- Biocides : modes of action and mechanisms of resistance / McDonnell -- A pragmatic approach to judicious selection and proper use of disinfectant and antiseptic agents in healthcare setting / Suljagic -- Extended activity of healthcare antiseptic products / Newman, Kaiser -- Disinfectant rotation in a cleaning/disinfection program for cleanrooms and controlled environments / Sutton -- Reprocessing flexible endoscopes : origin of standards, overview of structure/function, and review of recent outbreaks / Antonucci, Williams, Robinson -- Microbiological testing of disinfectants and decontaminants for critical surfaces / Klein -- Regulatory constraints on disinfectants and decontamination / Sarli -- Biofilms : a summarized account and control strategies / Nandakumar, Sreekumari -- Consequences of biofilms on indwelling medical devices : costs and prevention / Thomas, Nakaishi, Corum -- Infection-resistant implantable devices : biofilm problems and design strategies / Smith, Perera -- Infections of intracardiac devices / Yesenosky ... [et al.] -- Intrauterine devices : infections and biofilms / Pereira, Pruthi -- Antimicrobial urinary catheters / Stickler, Sabbuba -- Risk factors for post-operative infectious complications after abdominal surgery / Pessaux, Lermite.
- 2011 SpringerPai, Manjunath P.; Piscitelli, Stephen C.; Rodvold, Keith A.Introduction to Drug-Drug Interactions -- Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion -- Mechanisms of Drug Interactions II: Transport Proteins -- Drug-Food Interactions -- Interactions Between Herbs and Antiinfective Medications -- Drug-Cytokine Interactions -- Beta-Lactam Antibiotics -- Macrolides, Azalides, and Ketolides -- Quinolones -- Glycopeptides, Lipopeptides, and Lipoglycopeptides -- Miscellaneous Antibiotics -- Drugs for Tuberculosis -- Drug Interactions with Antiretrovirals for HIV Infection -- Non-HIV Antiviral Agents -- Antifungal Agents -- Antimalarial Agents -- Antiprotozoal and Anthelmintic Agents -- Drug Interaction Considerations Throughout Drug Development -- Probe Cocktail Studies -- Design and Data Analysis in Drug Interaction Studies.
- 2013 Future MedOmata, Masao.Hepatitis C virus infection : from discovery to eradication / Masao Omata & Tatsuo Kanda -- Interferons in clinical trials / Tatsuo Kanda, Osamu Yokosuka & Masao Omata -- Protease inhibitors / Marion Corouge, Philippe Sogni & Stanislas Pol -- NS5A inhibitor : daclatasvir / Kazuaki Chayama & C. Nelson Hayes -- Toll-like receptor agonists for nonresponders to HCV treatment : hope versus promise? / Valérie Martel-Laferrière & Douglas Dieterich -- Treatment options in HIV-HCV-coinfected patients / Philippe Sogni, Marion Corouge & Stanislas Pol -- Treatment options for dual HCV/HBV coinfection / Chun-Jen Liu & Jia-Horng Kao -- HCV treatment in patients with metabolic syndrome / Luigi E. Adinolfi, Rosa Zampino, Luciano Restivo, Amedeo Lonardo & Paola Loria -- Future directions in hepatitis C therapy / Stevan A. Gonzalez -- Index.
- 2012 WHOChapter 1. The evolving threat of antimicrobial resistance: Introduction -- Chapter 2. Surveillance to track antimicrobial use and resistance in bacteria -- Chapter 3. Measures to ensure better use of antibiotics -- Chapter 4. Reducing antimicrobial use in animal husbandry -- Chapter 5. Infection prevention and control in health-care facilities -- Chapter 6. Fostering innovation to combat antimicrobial resistance -- Chapter 7. The way forward: political commitment to enable options for action -- Appendix 1. List of 2001 WHO Global Strategy for Containment of Antimicrobial Resistance recommendations -- Appendix 2. List of 2011 WHO World Health Day six-point policy briefs.Also available: Print – 2012
- 2014 SpringerDerendorf, Hartmut; Mouton, Johan W.; Vinks, Alexander A.Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics is designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader is introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, from basic research to clinical situations.
- 2015 SpringerGoodsell, David S.; Richman, Douglas D.; Torbett, Bruce E.This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle.
- 2014 ClinicalKeyCarroll, Karen C.; Lee, Carlton K. K.; McMillan, Julia A.; Siberry, George K.Infectious agents and drugs of choice / Julia A. McMillan, Julia A. McMillan and George K. Siberry -- Recommended empiric antimicrobial therapy for selected clinical syndromes / Hiwot Hiruy, Swathi Gowtham, and Paul Sue -- Drug dosing in special circumstances / Angela Helder, Elizabeth A. Sinclair, and Carlton K.K. Lee -- Mechanisms of action and routes of administration of antimicrobial agents / Karen C. Carroll -- Mechanisms of drug resistance / Karen C. Carroll -- Therapeutic drug monitoring / Kristine A. Parbuoni and Carlton K.K. Lee -- Adverse drug reactions / Melissa D. Makii and Carlton K.K. Lee -- Recommended antimicrobial prophylaxis for selected infectious agents and conditions / Julia A. McMillan and George K. Siberry -- Antimicrobial desensitization protocols / Lisa A. Degnan and Carlton K.K. Lee -- Formulary / Carlton K.K. Lee.
- 2007 SpringerRello, Jordi.Approach to the febrile patient in the intensive care unit -- Cardiovascular monitoring in severe sepsis or septic shock -- Cardiopulmonary resuscitation and infection -- Opportunistic infections in the intensive care unit: a microbiologic overview -- Infections in critically ill solid organ transplant patients -- HIV in the intensive care unit -- Fungal infections -- Using protocols to improve the outcomes of critically ill patients with infection: focus on ventilator-associated pneumonia and severe sepsis -- Microbial surveillance in the intensive care unit -- Antimicrobial prophylaxis in the intensive care unit -- Antifungal therapy in the intensive care unit -- Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock -- Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy -- Methods for implementing antibiotic control in the intensive care unit -- Use of antibiotics in pregnant patients in the intensive care unit -- Immunomodulation in sepsis -- Antibiotic induced diarrhea -- Fundamentals of infection control and strategies for the intensive care unit -- Antibiotic resistance in the intensive care unit -- Epidemiology of pseudomonas aeruginosa in the intensive care unit -- How to control MRSA spread in the intensive care unit -- Epidemiology of acinetobacter baumannii in the intensive care unit -- Brain abscess -- Falciparum malaria -- Toxic shock syndromes -- Acute infective endocarditis -- Influenza -- Bloodstream infection in the intensive care unit -- Bloodstream infections in patients with total parenteral nutrition catheters -- Hemodialysis catheter-related infections -- Infection of pulmonary arterial and peripheral arterial catheters -- Prevention of catheter-related bloodstream infections in critical care patients -- Meningococcemia -- Septic shock -- Tracheobronchitis in the intensive care unit -- Sever community-acquired pneumonia -- Legionnaires' disease -- Adjunctive and supportive measures for community-acquired pneumonia -- Respiratory infection in immunocompromised neutropenic patients -- Pneumonia in non-neutropenic immunocompromised patients -- Community-acquired respiratory complications in the intensive care unit: pneumonia and acute exacerbations of COPD -- Management of hospital-associated pneumonia in the intensive care unit -- Assessment of resolution of ventilator associated pneumonia -- Invasive devices in the pathogenesis of nosocomial pneumonia -- Multiple organ dysfunction syndrome -- Sepsis in obstetrics -- Diagnosis and management of intra-abdominal sepsis -- Surgical site infection control in the critical care environment -- Severe soft tissue infections: a syndrome-based approach -- Vascular graft infections -- Acute mediastinitis -- Pancreatic infection -- Urinary tract infections -- Neurosurgical infections in intensive care unit patients -- Biliary tract infections.
- 2010 SpringerMainous, Arch G.; Pomeroy, Claire.
- 2010 ClinicalKeyAronson, J. K.; Meyler, L.Antibacerial Drugs -- Antiviral Drugs, Including Immunoglobulins and Interferons -- Antifungal Drugs -- Antiprotozoal and Antihelminthic Drugs -- Vaccines -- Disinfectants and Antiseptics.
- 2013 Future MedKrčméry, V.Antibiotic resistance : postantibiotic era is here / Vladimir Krcmery -- Current challenges in treating methicillin-resistant Staphylococcus aureus : what are the options? / Noha E.I. Sakka & Ian M . Gould -- Antimicrobial-resistant Streptococcus pneumoniae : trends and management / Michael R. Jacobs -- Emergence and management of drug-resistant enterococcal infections / William R. Miller, Barbara E. Murray & Cesar A. Arias -- Enterobacteriaceae that produce newer b-lactamases / Johann D.D. Pitout -- Extensively drug-resistant tuberculosis : new strains, new challenges / Megan Coffee -- Clinical significance of extended-spectrum b-lactamases / Jesés Rodréguez-Baño, Belén Gutiérrez, Lorena Lépez-Cerero & Alvaro Pascual -- Plasmid-mediated quinolone resistance / José Manuel Rodréguez-Marténez, Maréa Eliecer Cano, Jorge Calvo, Álvaro Pascual & Luis Marténez-Marténez -- Antibiotic resistance in the absence of antimicrobial use / Lucia Pallecchi, Alessandro Bartoloni, Eduardo Gotuzzo & Gian Maria Rossolini -- Resistance in bacteria of the food chain : epidemiology and control strategies / Lina Maria Cavaco & Frank Møller Aarestrup -- Measures to prevent antimicrobial resistance / Vhairi M. Bateman & Ian M. Gould -- Where does novel antibiotics R&D stand among other pharmaceutical products? / Glenn S. Tillotson -- Resistance to antiretroviral drugs / Manuela Colafigli, Simona Di Giambenedetto & Roberto Cauda -- Index.
- 2014 SpringerNuttall, Jeremy.One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.
- 2013 Future MedVermorken, Jan B.Monoclonal antibodies targeting EGFR/HER2 and clinical outcomes in cancer treatment / Jan B. Vermorken -- Colorectal cancer / Christian Rolfo, Giuseppe Bronte, Antonio Russo & Marc Peeters -- Breast cancer / Sevilay Altintas -- Lung cancer and genitourinary cancers / Dirk Schrijvers -- Tumors of the skin, the CNS and the head and neck / Pol Specenier -- Gynecologic cancers / Jan B. Vermorken -- Index.
- 2014 Thieme eNeurosurgeryHall, Walter A.; Kim, Peter D.Immunology of the CNS / Pragati Nigam and Maciej Lesniak -- Microbiological diagnosis of CNS / Yuriko Fukuta and Karin E. Byers -- Antibiotics and development of resistance / Peter D. Kim and Walter A. Hall -- Radiology of infections of the CNS / Kunal M. Patel and Charles L. Truwit -- Viral infections of the CNS -- Joseph B. Domachowske and Manika Suryadevara -- Fungal infections of the CNS / Walter A. Hall and Peter D. Kim -- Parasitic infections of the CNS / Ali Akhaddar and Mohamed Boucetta -- Bacterial brain abscess / Peter D. Kim and Walter A. Hall -- Meningeal infections / Manika Suryadevara and Joseph B. Domachowske -- Epidural and subdural infections / Sandi K. Lam and Peter C. Warnke -- Intracranial vascular infections / Hoon Choi, Walter A. Hall, and Eric M. Deshaies -- Vertebral column infections / Kyle I. Swanson and Daniel K. Resnick -- Spinal canal infections / Ian E. McCutcheon -- Neurosurgical antibiotic prophylaxis / DaraspreetKainth, Dino Terzic, and Stephen J. Haines -- Postoperative intracranial infections / Arya Nabavi, Friederike Knerlich-Lukoschus, and Andreas M. Stark -- Implanted devices and CNS infection / Ramesh Grandhi, Gillian Harrison, and Elizabeth C. Tyler-Kabara -- Pediatric CNS infections / Ian Mutchnick and Thomas Moriarty -- Immune compromise and CNS infections / Ouzi Nissim ... [et al.] -- Systemic infections in neurocritical care / Michael F. Regner ... [et al.].
- 2008 Springer ProtocolsChampney, W. Scott.
- 2006 SpringerBogner, Elke; Holzenburg, A.
- 2012 KargerKinane, Denis F.; Mombelli, Andrea.Subgingival biofilm structure / V. Zijnge, T. Ammann -- Microbial diversity and interactions in subgingival biofilm communities / P.I. Diaz -- Innate cellular responses to the periodontal biofilm / M. Benakanakere, D.F. Kinane -- Neutrophils in periodontal inflammation / D.A. Scott, J.L. Krauss -- Antimicrobial peptides in periodontal innate defense / S.-U. Gorr -- Modern approaches to non-surgical biofilm management / D.A. Apatzidou -- Animal models to study host-bacteria interactions involved in periodontitis / D.T. Graves ... [et al.] -- Antimicrobial advances in treating periodontal diseases / A. Mombelli -- Regenerative periodontal therapy / D.W.K. Kao, J.P. Fiorellini -- Paradigm shift in the pharmacological management of periodontal diseases / H. Hasturk, A. Kantarci, T.E. Van Dyke.
- Red Book Online is the online home of the Report of the AAP Committee on Infectious Diseases. Offering instant Web-based access, Includes complete text of the Red Book, plus the complete visual library of images from the Visual Red Book on CD-ROM and more.Also available: Print – 1970-<2012>
- Red Book Online is the online home of the Report of the AAP Committee on Infectious Diseases. Offering instant Web-based access, Includes complete text of the Red Book, plus the complete visual library of images from the Visual Red Book on CD-ROM and more.Also available: Print – 1970-<2012>
- Harrison's Principles of Internal Medicine
- AAP Red Book Online
- Robbins & Cotran Pathologic Basis of Disease
- Sabiston Textbook of Surgery
- Nelson's Textbook of Pediatrics
- Surgical Exposures in Orthopaedics
- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
- Red Book Online
- ICU Book
- Primary Care Medicine
- Campbell-Walsh Urology
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Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available.Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.
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