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Books by Subject

Anti-Infective Agents

  • 1. Historical introduction -- 2. Modes of action -- 3. The problem of resistance -- 4. Pharmacodynamics of anti-infective agents: target delineation and susceptibility breakpoint selection -- 5. Antimicrobial agents and the kidneys -- 6. Drug interactions involving anti-infective agents -- 7. Antibiotics and the immune system -- 8. General principles of antimicrobial chemotherapy -- 9. Laboratory control of antimicrobial therapy -- 10. Principles of chemop rophylaxis -- 11. Antibiotic policies -- 12. Aminoglycosides and aminocyclitols -- 13. β-Lactam antibiotics : cephalosporins -- 14. β-Lactam antibiotics: penicillins -- 15. Other β-lactam antibiotics -- 16. Chloramphenicol and thiamphenicol -- 17. Diaminopyrimidines -- 18. Fosfomycin and fosmidomycin -- 19. Fusidanes -- 20. Glycopeptides -- 21. Lincosamides -- 22. Macrolides -- 23. Mupirocin -- 24. Nitroimidazoles -- 25. Oxazolidinones -- 26. Quinolones -- 27. Rifamycins -- 28. Streptogramins -- 29. Sulfonamides -- 30. Tetracyclines -- 31. Miscellaneous antibacterial agents -- 32. Antifungal agents -- 33. Antimycobacterial agents -- 34. Anthelmintics -- 35. Antiprotozoal agents -- 36. Antiretroviral agents -- 37. Other antiviral agents -- 38. Sepsis -- 39. Abdominal and other surgical infections -- 40. Infections associated with neutropenia and transplantation -- 41. Infections in intensive care patients -- 42. Infections associated with implanted medical devices -- 43. Antiretroviral therapy for HIV -- 44. Infections of the upper respiratory tract -- 45. Infections of the lower respiratory tract -- 46. Endocarditis -- 47. Infections of the gastrointestinal tract -- 48. Hepatitis -- 49. Skin and soft-tissue infections -- 50. Bacterial infections of the central nervous system -- 51. Viral infections of the central nervous system -- 52. Bone and joint infections -- 53. Infections of the eye -- 54. Urinary tract infections -- 55. Infections in pregnancy -- 56. Sexually transmitted diseases -- 57. Leprosy -- 58. Tuberculosis and other mycobacterial infections -- 59. Superficial and mucocutaneous mycoses -- 60. Systemic fungal infections -- 61. Zoonoses -- 62. Malaria -- 63. Other protozoal infections -- 64. Helminthic infections.
  • Antibiotic resistance 2012, Springer
    Introduction to antibiotic resistance/ Richard Bax, David Griffin -- The origins of antibiotic resistance/ Gerard D. Wright -- Surveillance programmes and antibiotic resistance: worldwide and regional monitoring of antibiotic resistance trends/ Stephen Hawser -- Current and future challenges in the development of antimicrobial agents/ Robert P. Rennie -- The role of the outer membrane of gram-negative bacteria in antibiotic resistance: Ajax' shield or Achilles' heel?/ Malcolm G.P. Page -- Prevention of drug resistance by combined drug treatment of tuberculosis/ Denis A. Mitchison -- Nonmultiplying bacteria are profoundly tolerant to antibiotics / Yanmin Hu, Anthony Coates -- Persister cells: molecular mechanisms related to antibiotic tolerance / Kim Lewis -- Antimicrobial textiles / J. Vaun McArthur, R.C. Tuckfield, C. Baker-Austin -- Efflux: how bacteria use pumps to control their microenvironment / E. David G. McIntosh -- Antibiotics in phase II and III clinical trials / Anthony R.M. Coates, Gerry Halls.
  • Part 1. Considerations with antibiotic therapy -- Part 2. Antibacterial drugs -- Part 3. Antimycobacterial drugs -- Part 4. Antifungal drugs -- Part 5. Antiviral drugs -- Part 6. Antiparasitic Drugs -- Appendix 1. Selected normal human flora -- Appendix 2. Spectrum of activity -- Appendix 3. Empiric regimens for common infections -- Index.
  • Database
    Includes information on antimicrobial therapy and alternative therapy when the drug of choice cannot be given. The resource delivers information via review articles, capsule summaries, mini-reviews, and a guided PubMed search to pick up post-publication research.
  • This report examines, for the first time, the current status of surveillance and information on antimicrobial resistance (AMR) at country level worldwide, with particularly attention to antibacterial resistance.
  • Microbial drug resistance: a historical perspective / William C. Summers -- Ecology of antibiotic resistance genes / Abigail A. Salyers, Nadja Shoemaker, and David Schlesinger -- Global response systems that confer resistance / Paul F. Miller and Philip N. Rather -- Multidrug efflux pumps: structure, mechanism, and inhibition / Olga Lomovskaya ... [et al.] -- Mechanisms of aminoglycoside antibiotic resistance / Gerard D. Wright -- Resistance to [beta]-lactam antibiotics mediated by [beta]-lactamases : structure, mechanism, and evolution / Jooyoung Cha, Lakshmi P. Kotra, and Shahriar Mobashery -- Target modification as a mechanism of antimicrobial resistance / David C. Hooper -- Antibiotic permeability / Harry Taber -- Genetic methods for detecting bacterial resistance genes / Ad C. Fluit --Evolution and epidemiology of antibiotic-resistant pneumococci / Christopher Gerard Dowson and Krzysztof Trzcinski -- Antimicrobial resistance in the enterococcus / George M. Eliopoulos -- Methicillin resistance in staphylococcus aureus / Keeta S. Gilmore, Michael S. Gilmore, and Daniel F. Sahm -- Mechanism of drug resistance in mycobacterium tuberculosis / Alex S. Pym and Stewart T. Cole -- Antibiotic resistance in enterobacteria / Nafsika H. Georgopapadakou -- Resistance as a worldwide problem / Paul Shears -- Public health responses to antimicrobial resistance in outpatient and inpatient settings / Cindy R. Friedman and Arjun Srinivasan -- Antibacterial drug discovery in the 21st century / Steven J. Projan.
  • Classification of the Antibiotics -- Antibiotics Marketed in the EU -- Principles of Antibiotic Therapy -- The Most Common Errors in Antibiotic Therapy -- Important Infections and Their Microbiological Diagnosis -- Cooperation with Microbiologists -- Resistance of Major Clinical Pathogens -- The Most Frequent Pathogens- Choice of Antibiotics -- Antibiotics, Antimycotics: Spectrum- Dosage- Adverse Effects- Costs -- Antibiotic Therapy of the Principal Infections in Children and Adults -- Treatment of the Most Frequent Types of Bacterial Endocarditis -- Minimal Duration of Treatment for Bacterial Infections -- Failure of Antibiotic Therapy -- Fever of Unknown Origin: Differential Diagnosis -- Dosage of Antibiotics in Impaired Renal Function -- Antibiotic Therapy in Haemodialysis, Peritoneal Dialysis, and Continuous Haemofiltration -- Antibiotic Therapy During Pregnancy and Lactation -- Antibiotics in Liver Diseases -- Diffusion of Antibiotics in Cerebrospinal Fluid and in Cerebral Abscesses -- Local Antibiotics -- Prophylactic Antibiotic Therapy -- Physical Incompatibility of Antibiotics and Antimycotics in Infusion Solutions -- Useful Websites.
  • 1.Translational Strategies for Development of Antibody-Based Therapeutics: An Overview /Mohammad Tabrizi, Gadi Gazit Bornstein and Scott L. Klakamp --2.Discovery Process for Antibody-Based Therapeutics /Heather H. Shih --3.Technologies for the Generation of Human Antibodies /Ramesh R. Bhatt, John S. Haurum and C. Geoffrey Davis --4.Application of Antibody Engineering in the Development of Next Generation Antibody-Based Therapeutics /Randall J. Brezski and Juan Carlos Almagro --5.Biophysical Considerations for Development of Antibody-Based Therapeutics /Andrew W. Drake and Giuseppe A. Papalia --6.Considerations in Establishing Affinity Design Goals for Development of Antibody-Based Therapeutics /Mohammad Tabrizi --7.Bioanalytical Considerations for Development of Antibody-Based Therapeutics: Pharmacokinetics and Immunogenicity /Cherryl B. Funelas and Scott L. Klakamp --8.Preclinical Considerations for Development of Antibody-Based Therapeutics in Oncology /Gregory Landes and Kathleen Elias --9.Factors Impacting the Tumor Localization and Distribution of Antibody-Based Therapeutics in Oncology /David C. Blakey --10.Preclinical Safety Considerations for the Development of Antibody-Based Therapeutics /Lolke de Haan --11.Application of Pharmacokinetic/Pharmacodynamic Modeling in the Development of Antibody-Based Therapeutics /Donald E. Mager --12.Application of Population Pharmacokinetic-Pharmacodynamic Approaches in the Design of Translational Strategies for Development of Antibody-Based Therapeutics /Feng Jin --13.Translational Biomarkers: Essential Tools in Development of Antibody-Based Therapeutics /Mohammad A. Tabrizi and Cherryl B. Funelas --14.Translational Research in Alzheimer's Disease for Development of Antibody-Based Therapeutics /Eric C. Yuen, Enchi Liu and Gene G. Kinney --15.Considerations in Manufacturing Process Development for Antibody-Based Therapeutics /Paula C. Miller and Peiling Xu --16.Strategies for Development of Next Generation Antibody-Based Therapeutics /Mohammad Tabrizi and Gadi Gazit Bornstein --17.Immune Complex Therapies for Treatment of Immune Thrombocytopenia /Rong Deng and Joseph P. Balthasar --18.Application of Bioinformatics Principles for Target Evaluation /Anthony Carvalloza, Mohammad Fallahi and Sahba Tabrizifard --19.Concluding Remarks /Mohammad Tabrizi, Gadi Gazit Bornstein and Scott L. Klakamp.
  • Chapter 1. The evolving threat of antimicrobial resistance: Introduction -- Chapter 2. Surveillance to track antimicrobial use and resistance in bacteria -- Chapter 3. Measures to ensure better use of antibiotics -- Chapter 4. Reducing antimicrobial use in animal husbandry -- Chapter 5. Infection prevention and control in health-care facilities -- Chapter 6. Fostering innovation to combat antimicrobial resistance -- Chapter 7. The way forward: political commitment to enable options for action -- Appendix 1. List of 2001 WHO Global Strategy for Containment of Antimicrobial Resistance recommendations -- Appendix 2. List of 2011 WHO World Health Day six-point policy briefs.
  • Infectious agents and drugs of choice / Julia A. McMillan,Julia A. McMillan and George K. Siberry --Recommended empiric antimicrobial therapy for selected clinical syndromes /Hiwot Hiruy, Swathi Gowtham, and Paul Sue --Drug dosing in special circumstances /Angela Helder, Elizabeth A. Sinclair, and Carlton K.K. Lee --Mechanisms of action and routes of administration of antimicrobial agents /Karen C. Carroll --Mechanisms of drug resistance /Karen C. Carroll --Therapeutic drug monitoring /Kristine A. Parbuoni and Carlton K.K. Lee --Adverse drug reactions /Melissa D. Makii and Carlton K.K. Lee --Recommended antimicrobial prophylaxis for selected infectious agents and conditions /Julia A. McMillan and George K. Siberry --Antimicrobial desensitization protocols /Lisa A. Degnan and Carlton K.K. Lee --Formulary /Carlton K.K. Lee.
  • Antibacerial Drugs -- Antiviral Drugs, Including Immunoglobulins and Interferons -- Antifungal Drugs -- Antiprotozoal and Antihelminthic Drugs -- Vaccines -- Disinfectants and Antiseptics.
  • Monoclonal antibodies targeting EGFR/HER2 and clinical outcomes in cancer treatment / Jan B. Vermorken -- Colorectal cancer / Christian Rolfo, Giuseppe Bronte, Antonio Russo & Marc Peeters -- Breast cancer / Sevilay Altintas -- Lung cancer and genitourinary cancers / Dirk Schrijvers -- Tumors of the skin, the CNS and the head and neck / Pol Specenier -- Gynecologic cancers / Jan B. Vermorken -- Index.
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