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Allergy and Immunology

  • 2006 Springer
    [edited by] Gil Mor.
    Evolution of the mammalian reproductive tract and placentation / Susan Richman and Frederick Naftolin -- Toll-like receptors and pregnancy / Vikki M. Abrahams and Gil Mor -- IL-10 and pregnancy / Shaun P. Murphy and Surendra Sharma -- Th1/Th2 balance of the implantation site in humans / Shigeru Saito, Satomi Miyazaki, and Yasushi Sasaki -- The regulation of human trophoblast apoptosis and survival during pregnancy / Shawn L. Straszewski-Chavez and Gil Mor -- Macrophages and pregnancy / Gil Mor, Roberto Romero, and Vikki M. Abrahams -- Potential role of glucocorticoids in the pathophysiology of intrauterine growth restriction (IUGR) / Seth Guller, Yuehong Ma, and Men-Jean Lee -- NK cells and pregnancy / Mikael Eriksson, Satarupa Basu, and Charles L. Sentman -- The role of corticotropin-releasing hormone (CRH) on implantation and immunotolerance of the fetus / Sophia N. Kalantaridou ... [et al.] -- Indoleamine 2,3 dioxygenase-dependent T cell suppression and pregnancy / Babak Baban, Phillip R. Chandler, and Andrew L. Mellor -- Leukemia inhibitory factor in reproduction / Levent M. Senturk and Aydin Arici -- Characterization of human dendritic cells at the materno-fetal interface / Ulrike Kämmerer ... [et al.] -- MHC molecules of the preimplantation embryo and trophoblast / Martina Comiskey, Carol M. Warner, and Danny J. Schust -- Actions of seminal plasma cytokines in priming female reproductive tract receptivity for embryo implantation / Sarah A. Robertson ... [et al.] -- B7 family molecules in the placenta / Margaret G. Petroff -- The role of regulatory T cells in materno-fetal tolerance / Varuna R. Aluvihare and Alexander G. Betz -- The eutherian fetoembryonic defense system hypothesis: an update / Gary F. Clark ... [et al.] -- The nature and role of the decidual T cells / Lucia Mincheva-Nilsson and Vladimir Baranov -- Trophoblast cells as immune regulators / Gil Mor and Vikki M. Abrahams -- Inherited thrombophilias and early pregnancy loss / Jens Langhoff-Roos ... [et al.] -- Bi-directional cell trafficking during pregnancy: long-term consequences for human health / Kristina M. Adams and J. Lee Nelson -- Term and preterm parturition / Roberto Romero ... [et al.] -- Interleukin-1 and implantation / Jan-S. Krüssel ... [et al.] -- Immunology and pregnancy losses: HLA, autoantibodies and cellular immunity / Joanne Kwak-Kim, Joon Woo Kim, and Alice Gilman-Sachs.
  • 2014 Springer
    Ernst Rainer Weissenbacher.
    Fundamentals of immunology: Concepts of innate and specific immunity -- Mucosal immunology -- General immunology of the genital tract: Distinct features of the genital mucosal tissue -- Functions and regulation of innate immune responses in the human reproductive tract -- Functions and regulation of adaptive humoral and cell-mediated immunity in the female genital tract -- Immunization studies -- Immunology of menstruation {u2013} menstruation as an inflammatory process -- Immunology of genital tract infections: Viral infections of the genital tract -- Bacterial infections of the genital tract -- Candidiasis -- Trichomoniasis -- Immunology in reproductive medicine: Immunology of pregnancy -- Immunologic infertility -- Immunocontraceptive approaches.
  • 2013 Springer
    Laura Santambrogio, editor.
    Immunology of the Lymphatic System is a comprehensive study of the lymphatic system and its immunological role. It begins with lymphatic capillaries, their origin and development. It addresses lymph circulation, in general, with a special emphasis on lymph circulation in parenchymal organs. The next section focuses on lymph nodes, subcortical circulation and the conduit system. It discusses organs with no lymphatic system, such as the brain. Finally, it covers lymph composition and cells in the lymph. While primarily basic research, the volume touches upon elements of the clinical, as well, broadening its scope and appeal.
  • 2008 Springer
    Bruce Beutler, editor.
    The forward genetic dissection of afferent innate immunity / B. Beutler and E.M. Moresco -- Genetic analysis of resistance to infections in mice: A/J meets C57BL/6J / J.F. Marquis and P. Gros -- Host defenses against human papillomaviruses: lessons from epidermodysplasia verruciformis / G. Orth -- Innate resistance to flavivirus infections and the functions of 2'-5' oligoadenylate synthetases / T. Mashimo, D. Simon-Chazottes and J.L. Guenet -- Cmv1 and natural killer cell responses to murine cytomegalovirus infection / A.A. Scalzo and W.M. Yokoyama -- Genetic dissection of host resistance to Mycobacterium tuberculosis: the sst1 locus and the Ipr1 gene / I. Kramnik -- Scurfy, the Foxp3 locus, and the molecular basis of peripheral tolerance / M.W. Appleby and F. Ramsdell -- Fevers, genes, and innate immunity / J.G. Ryan and D.L. Kastner -- Itchy mice: the identification of a new pathway for the development of autoimmunity / L.E. Matesic, N.G. Copeland and N.A. Jenkins -- TIM gene family and their role in atopic diseases / D.T. Umetsu ... [et al.].
    Also available: Print – 2008
  • 2013 ClinicalKey
    David Male [and others].
    This textbook teaches the basic and clinical immunology concepts.
  • 2006
    [edited by] David K. Male, Jonathan Brostoff, David B. Roth, Ivan Roitt.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    Darren R. Flower, Yvonne Perrie, editors.
    This book seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology.
  • v. 2-, 2009- Springer
  • 2014 CRCnetBASE
    edited by Bharat B. Aggarwal, David Heber.
    Chapter 1. Evolution of innate and adaptive immunity / David Heber and Bharat B. Aggarwal -- chapter 2. Cellular mechanisms of cytokine activation / David Heber and Bharat B. Aggarwal -- chapter 3. Cellular lipids and inflammation / David Heber and Susanne Henning -- chapter 4. Biomarkers of inflammation and the Western diet / David Heber and Susanne Henning -- chapter 5. Phytochemicals and immune function / David Heber -- chapter 6. Genetic and environmental modifiers of immune function / David Heber -- chapter 7. Cancer and inflammation / David Heber -- chapter 8. Abdominal obesity : pathophysiology and related metabolic complications / Ana F.T.A. Junqueria and Caroline M. Apovian -- chapter 9. Type 2 diabetes and inflammation / Zhaoping Li and David Heber -- chapter 10. Heart disease and inflammation / Kaveh Daniel Navab -- chapter 11. Chronic kidney disease and inflammation / Karl J. Neff and Carel Le Roux -- chapter 12. Alzheimer's disease and inflammation / Stephen T. Chen and Gary W. Small -- chapter 13. Nutrition in autoimmunity : a focus on systemic lupus erythematosus and rheumatoid arthritis / Maureen McMahon -- chapter 14. Asthma and inflammation / Andre Nel and David Heber -- chapter 15. Muscle and immune function / Anthony Thomas and David Heber -- chapter 16. Approaches to reducing abdominal obesity / Zhaoping Li and David Heber -- chapter 17. Barriers to fruit and vegetable consumption and practical strategies for increasing fruit and vegetable intake / Susan Bowerman -- chapter 18. Healthy fats and oils : balancing omega-3 and omega-6 acids in tissues / Bill Lands -- chapter 19. Spices and dietary supplements with anti-inflammatory activity / Bharat B. Aggarwal and David Heber.
  • 2015 Karger
    volume editors, Olivier Michielin, George Coukos.
    Immunotherapies in early and advanced renal cell cancer / Kasenda, B., Larkin, J., Gore, M. -- Immunotherapy of brain tumors / Dutoit, V., Migliorini, D., Walker, P.R., Dietrich, P.-Y. -- Immunotherapy of melanoma / Snyder, A., Zamarin, D., Wolchok, J.D. -- Immunotherapy of breast cancer / Criscitiello, C., Curigliano, G. -- Current developments in actively personalized cancer vaccination with a focus on RNA as the drug format / Diken, M., Kreiter, S., Kloke, B., Sahin, U. -- Immune checkpoint inhibitors / Haanen, J.B.A.G., Robert, C. -- Radiotherapy and immunotherapy : improving cancer treatment through synergy / Reynders, K., De Ruysscher, D. -- Combinations therapies / Reinmuth, N., Reck, M. -- Promise of immunotherapy in lung cancer / Shanker, A., Dikov, M.M., Carbone, D.P. -- T cell engineering / Pircher, M., Schirrmann, T., Petrausch, U.
  • 2008 Springer
    Manzoor M. Khan.
  • 2006 ScienceDirect
    [edited by] Virgil E.J.C. Schijns, Derek T. O'Hagan.
    Microparticles as vaccine delivery systems / Derek T. O'Hagan -- MF59: a safe and potent adjuvant for human use / Audino Podda, Giuseppe Del Giudice, and Derek T. O'Hagan -- Development and evaluation of AS04, a novel and improved adjuvant system containing MPL and aluminium salt / Nathalie Garçon, Marcelle van Mechelen, and Martine Wettendorff -- Virosomes for vaccine delivery / Ian C. Metcalfe and Reinhard Glück -- The ISCOMATRIX adjuvant / Debbie Drane and Martin J. Pearse -- Mineral adjuvants / Erik B. Lindblad -- Mucosal adjuvants based on cholera toxin and E. coli heat-labile enterotoxin / Jan Holmgren ... [et al.] -- Transcutaneous immunization using the heat-labile enterotoxin of E. coli as an adjuvant / Richard T. Kenney and Gregory M. Glenn -- T cell adjuvants and novel strategies for their identification / Laurence Van Overvelt and Philippe Moingeon -- Vaccination to treat noninfectious diseases: surveying the opportunities / Stephen W. Martin and Martin F. Bachmann -- Clinical evaluation of adjuvants / Jakub K. Simon and Robert Edelman -- Regulatory considerations in the nonclinical safety assessment of adjuvanted preventive vaccines / Elizabeth M. Sutkowski and Marion F. Gruber. Unravelling "the immunologist's dirty little secret" / Virgil E.J.C. Schijns -- Dendritic cells as targets and tools in vaccines / Imerio Capone, Paola Rizza, and Filippo Belardelli -- Host-derived molecules as adjuvants / Tom Barr, Jennifer Carlring, and Andrew W. Heath -- Innate immune mechanisms and the identification of immune potentiators as vaccine adjuvants / Achal Pashine, Jeffrey B. Ulmer, and Nicholas M. Valiante -- CpG oligodeoxynucleotides as vaccine adjuvants / Michael J. McCluskie and Risini D. Weeratna -- Toll-like receptor 4 agonists as vaccine adjuvants / David H. Persing ... [et al.] -- Immunomodulatory adjuvants from Quillaja saponaria / Charlotte Read Kensil --
    Also available: Print – 2006
  • 2013 Springer Protocols
    edited by Kelly M. Fulton, Susan M. Twine.
    Introduction to the immune system / Scott McComb ... [et al.] -- Immunoproteomics : current technology and applications / Kelly M. Fulton and Susan M. Twine -- Antigen identification using SEREX / Ugur Sahin and Özlem Türeci -- Antigen discovery using whole-genome phage display libraries / Elisa Beghetto and Nicola Gargano -- Methods and applications of serological proteome analysis / Kelly M. Fulton ... [et al.] -- Pre-absorbed immunoproteomics : a novel method for the detection of bacterial surface proteins / Guangjin Liu, Wei Zhang, and Chengping Lu -- Identification of the antigen content of electroimmunoprecipitates / N. Helena Beyer and Niels H.H. Heegaard -- Immunoproteomics approach to screen the antigenicity of the influenza virus / Kevin M. Downard -- In vivo microbial antigen discovery (InMAD) to identify diagnostic proteins and polysaccharides that are circulating during microbial infections / Sindy J. Chaves ... [et al.] -- Chemo-enzymatic production of O-glycopeptides for the detection of serum glycopeptide antibodies / Alexander Nøstdal and Hans H. Wandall -- Enrichment and characterization of glycopeptide epitopes from complex mixtures / Luc Tessier, Kelly M. Fulton, and Susan M. Twine -- Whole-cell MALDI-TOF mass spectrometry : a tool for immune cell analysis and characterization / Richard Ouedraogo ... [et al.] -- Cell-based arrays for the identification of interacting polypeptide domains or epitopes / Richard H. Maier, Christina J. Maier, and Kamil Önder -- Identification and quantitation of MHC class II-bound peptides from mouse spleen dendritic cells by immunoprecipitation and mass spectrometry analysis / Leonia Bozzacco and Haiqiang Yu -- Construction and screening of an antigen-derived peptide library displayed on yeast cell surface for CD4+ T cell epitope identification / Fei Wen and Huimin Zhao -- Profiling of cytokine and chemokine responses using multiplex bead array technology / Greg Harris and Wangxue Chen -- Preparation of the low molecular weight serum proteome for mass spectrometry analysis / Timothy J. Waybright ... [et al.] -- Identification of protein biomarkers in human serum using iTRAQ and shotgun mass spectrometry / Theodoros A. Koutroukides ... [et al.] -- Genome-based bioinformatic prediction of major histocompatibility complex (MHC) epitopes / Simon J. Foote -- Structure-based prediction of major histocompatibility complex (MHC) epitopes / Andrew J. Bordner -- Prioritization of therapeutic targets of inflammation using proteomics, bioinformatics, and in silico cell-cell interactomics / Arsalan S. Haqqani and Danica B. Stanimirovic -- Commercial considerations for immunoproteomics / Scott M. Ferguson.
  • 2015 Springer Protocols
    edited by Albert C. Shaw.
    Isolation of lipid rafts from human neutrophils by density gradient centrifugation / Carl Fortin and Tamas Fülöp -- Flow cytometry analysis of NK cell phenotype and function in aging / Raquel Tarazona ... [et al.] -- Flow cytometric identification of fibrocytes in the human circulation / Xinyuan Hu, Erin M. DeBiasi, and Erica L. Herzog -- Experimental approaches to tissue injury and repair in advanced age / Aleah L. Brubaker, Stewart R. Carter, and Elizabeth J. Kovacs -- Multicolor digital flow cytometry in human translational immunology / Samit R. Joshi, Subhasis Mohanty, and Albert C. Shaw -- Flow cytometry-based methods to characterize immune senescence in nonhuman primates / Christine Meyer ... [et al.] -- Multiparameter phenotyping of human PBMCs using mass cytometry / Michael D. Leipold, Evan W. Newell, and Holden T. Maecker -- Imaging immunosenescence / Feng Qian and Ruth R. Montgomery -- Activation-induced cytidine deaminase and switched memory B cells as predictors of effective in vivo responses to the influenza vaccine / Daniela Frasca, Alain Diaz, and Bonnie B. Blomberg -- Analyzing the effect of aging on CD8+ T-cell phenotype using flow cytometry / Min Sun Shin and Insoo Kang -- Cell-mediated immune response to influenza using ex vivo stimulation and assays of cytokine and granzyme B responses / Janet E. McElhaney and Beth Gentleman -- Assays for monitoring macroautophagy activity in T cells / Yair Botbol and Fernando Macian -- Fluorescence-based approaches for quantitative assessment of protein carbonylation, protein disulfides, and protein conformation in biological tissues / Asish R. Chaudhuri ... [et al.] -- Monitoring the DNA damage response at dysfunctional telomeres / Rekha Rai and Sandy Chang -- Single-cell analysis of T-cell receptor Αβ repertoire / Pradyot Dash, George C. Wang, and Paul G. Thomas -- Assessment of B cell repertoire in humans / Yu-Chang Wu, David Kipling, and Deborah Dunn-Walters -- Laboratory and data analysis methods for characterization of human B cell repertoires by high-throughput DNA sequencing / Chen Wang ... [et al.] -- Discovery of novel microRNAs in aging Caenorhabditis elegans / Alexandre de Lencastre and Frank Slack -- Analysis of DNA methylation by pyrosequencing / Colin Delaney, Sanjay K. Garg, and Raymond Yung.
  • 2012 Springer
    Andreas Thiel, editor.
  • 2013 Springer
    Jos A. Bosch, Anna C. Phillips, Janet M. Lord, editors ; foreword by Keith W. Kelley.
    This book presents the first multi-disciplinary approach to the understanding of immune aging, or immunosenescence; it combines biological data and clinical observations with psychological, social, and behavioral perspectives and is thus a valuable and timely contribution to the literature in this area. Contributors, all eminent scholars in their respective fields, review thoroughly the state of the art in research that examines how psychological and behavioral factors influence the rate and extent of immune system aging.
  • 2012 Future Med
    editors, Yehuda Shoenfeld, Pier Luigi Meroni, Ricard Cervera.
    Immunotherapeutic agents for SLE / Yehuda Shoenfeld, Pier Luigi Meroni & Ricard Cervera -- Immunopathogenesis of SLE and drug targets / Arvind Kaul, David D'Cruz & Graham R.V. Hughes -- Rituximab in SLE / Cándido Díaz-Lagares, Manuel Ramos-Casals & Munther A. Khamashta -- Belimumab in SLE / Ricard Cervera & Gerard Espinosa -- Epratuzumab in SLE / David M. Goldenberg & Daniel J. Wallace -- Intravenous immunoglobulin therapy for SLE / Ziv Rozman & Gisele Zandman-Goddard -- Other novel immunotherapeutic agents in the pipeline and future directions / Ana M. Bertoli & Graciela S. Alarcón -- Index.
  • 2007 Springer
    A. Radbruch ... [et al.], editors.
  • 2015 ScienceDirect
    edited by Xiang-Yang Wang and Paul B. Fisher.
  • 2006 Springer
    edited by Mary L. Disis.
    Discovery of target molecules for cancer immunotherapy by genetic and bioinformatic approaches -- Current strategies for the identification of immunogenic epitopes of tumor antigens -- Current and future role of natural-killer cells in cancer immunotherapy -- The role of immune monitoring in evaluating cancer immunotherapy -- Statistical analysis of immune response assays -- DNA vaccines for cancer immunotherapy -- Dendritic cells -- Different approaches to dendritic cell-based cancer immunotherapy -- Anti-idiotype antibody vaccines for the immunotherapy of cancer -- Autologous tumor-derived heat shock protein vaccine as a new paradigm for individualized cancer therapeutics -- Tumor-reactive T-cells for adoptive immunotherapy -- T-cell adoptive immunotherapy of cancer: from translational models to clinical significance -- Retroviral-mediated gene transfer for engineering tumor-reactive T-cells -- Harnessing the potential of graft-vs-tumor -- Tumor-induced immune suppression and immune escape: mechanisms and impact on the outcome of immunotherapy of malignant disease -- The tumor microenvironment: regulation of antitumor immunity and implications for immunotherapy -- Manipulation of lymphocyte homeostasis for enhancing antitumor immunity -- Fast-lane evolution in the tumor microenvironment -- Manipulating immunological checkpoints to maximize antitumor immunity -- Interleukin-2 as cancer therapy -- Biological and clinical properties of the type 1 interferons -- Promising g [gamma]-chain cytokines for cancer immunotherapy: interleukins-7, -15, and -21 as vaccine adjuvants, growth factors -- The therapeutic use of natural-killer cells in hematological malignancies -- Antibody therapy for solid tumors -- Antibody therapy for non-Hodgkin's lymphoma -- Approaches to in vivo imaging of cancer immunotherapy -- Design issues for early-stage clinical trials for cancer vaccines -- Monoclonal antibody therapy for cancer.
  • 2010 Springer Protocols
    edited by Patricia Yotnda.
    Hypoxic tumors and their effect on immune cells and cancer therapy / Patricia Yotnda, Danli Wu, and Anna May Swanson -- Characterization of regulatory T cells in tumor suppressive microenvironments / Guangyong Peng -- Generation of cytotoxic T lymphocytes for immunotherapy of EBV-associated malignancies / Corey Smith and Rajiv Khanna -- Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy / Dean A. Lee, Michael R. Verneris, and Dario Campana -- Enhanced migration of human dendritic cells expressing inducible CD40 / Natalia Lapteva -- Differentiation of human embryonic stem cells into hematopoietic cells in vitro / Eun-Mi Kim and Nicholas Zavazava -- Gene therapy to improve migration of T cells to the tumor site / Antonio Di Stasi, Biagio De Angelis, and Barbara Savoldo -- Gene therapy to improve function of T cells for adoptive immunotherapy / Concetta Quintarelli, Barbara Savoldo, and Gianpietro Dotti -- Cytokine-FC fusion genes as molecular adjuvants for DNA vaccines / Daniel Hirschhorn-Cymerman and Miguel-Angel Perales -- Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials / Jung Hee Woo ... [et al.] -- Construction of human antibody gene libraries and selection of antibodies by phage display / Thomas Schirrmann and Michael Hust -- Identification of immunogenic peptides of the self-tumor antigen : our experience with telomerase reverse transcriptase / Xochitl Cortez-Gonzalez and Maurizio Zanetti -- Rescue, amplification, purification, and PEGylation of replication defective first-generation adenoviral vectors / Michael A. Barry, Eric A. Weaver, and Sean E. Hofherr -- Adenovirus-mediated interleukin (IL)-24 immunotherapy for cancer / Rajagopal Ramesh ... [et al.] -- Liposomes for gene transfer in cancer therapy / Nancy Smyth Templeton -- Oncolytic HSV as a vector in cancer immunotherapy / Hongtao Li and Xiaoliu Zhang -- Generation of chimeric T-cell receptor transgenes and their efficient transfer in primary mouse T lymphocytes / Linda J. Howland, Nicole M. Haynes, and Phillip K. Darcy -- Multi-walled carbon nanotube (MWCNT) synthesis, preparation, labeling, and functionalization / Babak Kateb ... [et al.] -- Cellular immunotherapy of cancer / Fatma V. Okur and Malcolm K. Brenner.
  • 2012 Springer
    Rodney R. Dietert, Robert W. Luebke, editors.
    Immunotoxicity, Immune Dysfunction, and Chronic Disease is among the first books to illustrate the linkage between environmental risk factors (e.g., chemicals, drugs, diet, lifestyles), environmentally-induced immune dysfunction and the full range of resulting chronic diseases and conditions. There is a detailed discussion of specific immune-based chronic diseases and conditions that emerge in children and adults and affect different physiological systems. The book integrates a consideration of risk factors and specific immunotoxic alterations with disease outcomes. A significant number of diseases and conditions are discussed, such as systemic allergic diseases affecting the lung, skin and gastrointestinal tract, systemic autoimmune diseases (type 1 diabetes, multiple sclerosis and lupus) and chronic conditions that are not traditionally associated with chemically-mediated immunomodulation (depression, frailty, and atherosclerosis). Inflammatory dysregulation is a common thread that connects many of the diseases and conditions discussed in this book and provides a central focus. Individual chapters are organized by disease with the addition of chapters that provide integrative information on: 1) patterns of disease comorbidities and 2) the safety testing of chemicals and drugs to reduce the risk of immune dysfunction. Each chapter contains a summary of key points as well as recommendations when appropriate. The book stresses the benefits of identifying the environmental risk factors of immune-mediated chronic disease and the potential to reduce the prevalence of these diseases and conditions. This volume is a valuable resource for researchers, clinicians, risk assessors and regulators and students.
  • 2007 CRCnetBASE
    edited by Robert Luebke, Robert House, and Ian Kim.
  • v.1, 2004 ScienceDirect
    J. Descotes.
    v. 1. Principles and methods of immunotoxicology.
  • 2007 Springer
    edited by Darren Flower and Jon Timmis.
  • 2012 Springer
    Joan Stein-Streilein, editor.
    The Eye as a model for immune privilege -- Immune privilege of the testis: meaning, mechanisms, and manifestations -- The Role of intrauterine immune privilege in perinatal infectious diseases -- The Liver as an immune-privileged site -- Immune homeostasis of the lung: the role of regulatory NKT cells in asthma -- Immune homeostasis of the gut.
  • 2013 Springer Protocols
    edited by Christine M. De Nardo and Eicke Latz.
    Assessing [beta]-amyloid-induced NLRP3 inflammasome activation in primary microglia / Mareike Schnaars, Hannes Beckert, and Annett Halle -- Activating the NLRP3 inflammasome using the amyloidogenic peptide IAPP / Clara Westwell-Roper [and others] -- Assessment and quantification of crystal-induced lysosomal damage / Peter Duewell and Eicke Latz -- Assessment of inflammasome activation in primary human immune cells / Theo S. Plantinga, Leo A.B. Joosten, and Mihai G. Netea -- NLRP3 inflammasome activation and cytotoxicity induced by particulate adjuvants / Marie Yang [and others] -- Measuring inflammasome activation in response to bacterial infection / Petr Broz and Denise M. Monack -- Detection of pyroptosis by measuring released lactate dehydrogenase activity / Manira Rayamajhi, Yue Zhang, and Edward A. Miao -- ASC speck formation as a readout for inflammasome activation / Andrea Stutz [and others] -- Immunoblotting for active caspase-1 / Christopher Jakobs [and others] -- Inflammasome activation and inhibition in primary murine bone marrow-derived cells, and assays for IL-1[alpha], IL-1[beta], and caspase-1 / Katharina S. Schneider, Christina J. Thomas, and Olaf Gross -- Reconstituting the NLRP1 inflammasome in vitro / Benjamin Faustin and John C. Reed -- Assessing ATP binding and hydrolysis by NLR proteins / Jinyao Mo and Joseph A. Duncan -- Blue native polyacrylamide gel electrophoresis to monitor inflammasome assembly and composition / Eric M. Kofoed and Russell E. Vance -- Analysis of microbiota alterations in inflammasome-deficient mice / Eran Elinav, Christoph A. Thaiss, and Richard A. Flavell -- Quantification of adipose tissue leukocytosis in obesity / Ryan Grant [and others] -- In vivo evaluation of neutrophil recruitment in response to sterile particulates / Tamiko Yanagida, Kaoru Orihashi, and Hajime Kono.
  • 2011 Springer
    Isabelle Couillin, Virginie Pétrilli, Fabio Martinon, editors.
  • 2014 ScienceDirect
    edited by Irfan Rahman, Debasis Bagchi.
    The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field.
  • 2012 Springer
    Georg Wick, Cecilia Grundtman, [editors].
    Ch. 1. Historical reflections on the inflammatory aspects of atherosclerosis -- Ch. 2. Morphology of atherosclerotic lesions -- Ch. 3. Clinical manifestations of atherosclerosis -- Ch. 4. Intra-aortic hematopoietic cells -- Ch. 5. The vascular-associated lymphoid tissue (VALT) -- Ch. 6. Vascular endothelial cells as immunological targets in atherosclerosis -- Ch. 7. The role of adhesion molecules and intimal dendritic cells in the initiation of atherosclerosis -- Ch. 8. Animal models of atherosclerosis -- Ch. 9. A Darwinian-evolutionary concept for atherogenesis: the role of immunity to HSP60 -- Ch. 10. Mediators of vascular inflammation -- Ch. 11. Pentraxins and atherosclerosis -- Ch. 12. Interleukin-33 and atherosclerosis -- Ch. 13. Proteomics of atherosclerosis -- Ch. 14. Adipokines, inflammation, and atherosclerosis -- Ch. 15. Natural antibodies and atherosclerosis -- Ch. 16. NK/NKT cells and atherosclerosis -- Ch. 17. Macrophages and atherosclerosis -- Ch. 18. Host pattern recognition receptors (toll-like receptors, RIG-I-Like receptors, NOD-like receptors) and atherosclerosis -- Ch. 19. Humoral antibodies -- Ch. 20. Adaptive T Cell immunity -- Ch. 21. Immunity to low-density lipoprotein -- Ch. 22. Extracellular matrix and smooth muscle cells -- Ch. 23. The role of infection in atherosclerosis and in plaque stability -- Ch. 24. Inflammatory biomarkers -- Ch. 25. Atherosclerosis in rheumatic diseases -- Ch. 26. Anti-inflammatory therapeutic approaches -- Ch. 27. Vaccination against atherosclerosis -- Ch. 28. Endocrinological aspects of atherosclerosis -- Ch. 29. Imaging of atherosclerosis -- Ch. 30. Future directions of atherosclerosis research and translation into clinical application -- Ch. 31. Controversies and open questions -- Index.
  • 2014 Springer
    Bharat B. Aggarwal, Bokyung Sung, Subash Chandre Gupta, editors.
    The role of inflammation in lung cancer / Mónica Gomes, Ana Luísa Teixeira, Ana Coelho, António Araújo and Rui Medeiros -- The role of inflammation in colon cancer / Naveena B. Janakiram and Chinthalapally V. Rao -- The role of inflammation in inflammatory breast cancer / Tamer M. Fouad, Takahiro Kogawa, James M. Reuben and Naoto T. Ueno -- The role of inflammation in brain cancer / James L. Sowers, Kenneth M. Johnson, Charles Conrad, Joel T. Patterson and Lawrence C. Sowers -- The role of inflammation in head and neck cancer / Marcelo Bonomi, Alexis Patsias, Marshall Posner and Andrew Sikora -- The role of inflammation in pancreatic cancer / Simone Hausmann, Bo Kong, Christoph Michalski, Mert Erkan and Helmut Friess -- The role of inflammation in prostate cancer / Karen S. Sfanos, Heidi A. Hempel and Angelo M. De Marzo -- The role of inflammation in bladder cancer / Georgios Gakis -- The role of inflammation in kidney cancer / Antonio Roma De Vivar Chevez, James Finke and Ronald Bukowski -- The role of inflammation in gastric cancer / Kazim Senol, Murat Bulut Özkan, Selahattin Vural and Mesut Tez -- The role of inflammation in sarcoma / Jürgen Radons -- The role of inflammation in lymphoma / Antonino Carbone, Claudio Tripodo, Carmelo Carlo-Stella, Armando Santoro and Annunziata Gloghini -- The role of inflammation in leukaemia / Janusz Krawczyk, Michael O'Dwyer, Ronan Swords, Ciara Freeman and Francis J Giles -- The role of inflammatory cells in angiogenesis in multiple myeloma / Domenico Ribatti and Angelo Vacca -- The role of inflammation in cervical cancer / S. Deivendran, K. Hezlin Marzook and M. Radhakrishna Pillai -- The role of inflammation in liver cancer / Anupam Bishayee -- The role of inflammation in skin cancer / Girish B. Maru, Khushboo Gandhi, Asha Ramchandani and Gaurav Kumar.
    Also available: Print – 2014
  • v. 1-2, 2009 Springer Protocols
    v. 2, 2009 Springer Protocols
    edited by Serguei V. Kozlov.
    v. 1. Experimental models and practical approaches -- v. 2. Molecular analysis and pathways.
  • 2013 Karger
    volume editors, A. Halaris, Maywood, Ill., B.E. Leonard, Galway.
    Basic aspects of the immunology of neuroinflammation / Wohleb, E.S.; Godbout, J.P. -- Stress and neuroinflammation / Grippo, A.J., Scotti, M.-A.L. -- Role of inflammation in depression : implications for phenomenology, pathophysiology and treatment / Raison, C.L., Miller, A.H. -- Virus infection as a cause of inflammation in psychiatric disorders / Bechter, K. -- Inflammation, neurotoxins and psychiatric disorders / Myint, A.-M. -- Essential fatty acids as potential anti-inflammatory agents in the treatment of affective disorders / Song, C. -- The brain-gut axis : a target for treating stress-related disorders / Scott, L.V., Clarke, G., Dinan, T.G. -- The question of pro-inflammatory immune activity in schizophrenia and the potential importance of anti-inflammatory drugs / Arolt, V., Ambrée, O. -- Inflammation as the cause of the metabolic syndrome in depression / Leonard, B.E. -- Glucocorticoids and inflammation : a double-headed sword in depression? / Horowitz, M.A. ... [et al.] -- Co-morbidity between cardiovascular pathology and depression : role of inflammation -- Halaris, A. -- Inflammatory and oxidative and nitrosative stress cascades as new drug targets in myalgic encephalomyelitis and chronic fatigue syndrome -- Maes, M. -- Peripheral inflammation and cognitive aging -- Lim, A., Krajina, K., Marsland, A.L. -- Inflammation in suicidality : implications for novel treatment options / Janelidze, S., Brundin, L.
  • 2012 CRCnetBASE
    edited by Bharat B. Aggarwal, Sunil Krishnan, Sushovan Guha.
    "Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to chronic diseases through inflammation. While short-term, acute inflammation generated by the immune system serves a therapeutic role, chronic low-level inflammation that may persist "silently" for decades is responsible for chronic diseases. Inflammation, Lifestyle, and Chronic Diseases: The Silent Link describes the role of dysregulated inflammation in persistent and recurring diseases. It investigates links to lifestyle and presents research on how the suppression of proinflammatory pathways may provide opportunities for both prevention and treatment of chronic diseases. The book covers neurodegenerative diseases, pulmonary diseases, asthma, rheumatic and arthritic diseases, skin disease, heart disease, chronic wounds, infectious disease, neuropsychiatric disorders such as depression, gastrointestinal diseases, insulin resistance, and cancer, many of which are also diseases of old age. For each chronic disease, contributors review the clinical and scientific literature and examine current and potential therapies, including conventional pharmacotherapies as well as natural products. Noting that the long-term use of steroids and nonsteroidal anti-inflammatory drugs (NSAIDs) can cause adverse side effects, many of the chapters address the role of dietary agents such as fruits, vegetables, legumes, pulses, nuts, and spices as ideal anti-inflammatory agents that can be consumed regularly. The book also suggests directions for further research. Clinical and science researchers, students, and health professionals interested in the link between inflammation, lifestyle, and chronic diseases will find this an informative resource"--Provided by publisher.
  • 2015 Springer
    Mieczyslaw Pokorski, editor.
    The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.
    Also available: Print – 2015
  • 2015 Springer
    Michael Pugia, editor.
    Part 1. Introduction -- 1. Impact of inflammation and the innate immunity response in obesity mediated diabetes (lit review) -- Part 2. Impact of complement on diabetic disease -- 2. Complement and Complement Regulatory Proteins in Diabetes -- Part 3. Role of C terminal fragment of adiponectin receptor in inhibition of insulin degradation -- 3. Development of adiponectin receptor C terminal fragment bioassays -- 4. Protease inhibition and biological distribution of the C terminal fragment of adiponectin receptor -- 5. Cell & biological models for the C terminal fragment of adiponectin receptor -- 6. C-Terminal fragment of adiponectin receptor clinical correlations -- Part 4. Uristatin assay for prediction of renal and other clinical events -- 7. Uristatin immunoassay usage in glomerular nephritis assessment -- 8. Acute Response of Uristatin in Surgery -- 9. Cardiovascular and metabolic syndrome impact on uristatin -- 10. Uristatin anti-inflammatory cellular signaling -- Part 5. Summary -- 11. Overview of progress in new markers for diabetes inflammation (Literatue Review).
    Also available: Print – 2015
  • 2014 Springer
    Richard W. Compans, Michael B.A. Oldstone, editors.
    This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
  • 2015 Springer
    Michael B.A. Oldstone, Richard W. Compans, editors.
    Part I. Innate immunity. The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options / John R. Teijaro -- Innate immune sensing and response to influenza / Bali Pulendran and Mohan S. Maddur -- The NS1 protein: a multitasking virulence factor / Juan Ayllon and Adolfo García-Sastre -- Role of NK cells in influenza infection / Stacey Shultz-Cherry -- Host detection and the stealthy phenotype in influenza virus infection / Pradyot Dash and Paul G. Thomas -- Part II. Vaccines and adaptive immunity. Inactivated and adjuvanted influenza vaccines / Giuseppe Del Giudice and Rino Rappuoli -- Live attenuated influenza vaccine / Hong Jin and Kanta Subbarao -- Design of alternative live attenuated influenza virus vaccines / Courtney Finch, Weizhong Li and Daniel R. Perez -- Rapid production of synthetic influenza vaccines / Philip R. Dormitzer -- Influenza neuraminidase as a vaccine antigen / Maryna C. Eichelberger and Hongquan Wan -- Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin / Florian Krammer, Peter Palese and John Steel -- Structural characterization of viral epitopes recognized by broadly cross-reactive antibodies / Peter S. Lee and Ian A. Wilson -- Skin immunization with influenza vaccines / Ioanna Skountzou and Richard W. Compans -- Mucosal immunization and adjuvants / Hideki Hasegawa, Elly van Reit and Hiroshi Kida -- B cell responses to influenza infection and vaccination / Christopher Chiu, Ali H. Ellebedy, Jens Wrammert and Rafi Ahmed -- Memory CD4 T cells in influenza / Kyra D. Zens and Donna L. Farber -- The effector T cell response to influenza infection / Matthew M. Hufford, Taeg S. Kim, Jie Sun and Thomas J. Braciale -- Part III. New antiviral discovery. Antiviral effects of inhibiting host gene expression / Ralph A. Tripp and S. Mark Tompkins -- Index.
  • 2011 Springer
    Rino Rappuoli, Giuseppe Del Giudice, editors.
    pt. 1. Evolution and epidemiology -- pt. 2. Immunity and vaccine strategies -- pt. 3. Economic and social implications.
  • 2008 Springer
    Eitan Yefenof, editor.
  • 2014 Springer Protocols
    edited by Hans-Joachim Anders, Adriana Migliorini.
    Detection of RNA modifications by HPLC analysis and competitive ELISA / Gernot Nees, Andreas Kaufmann, and Stefan Bauer -- Enzymatic synthesis and purification of a defined RIG-I ligand / Marion Goldeck ... [et al.] -- Crystallization of mouse RIG-I ATPase domain : in situ proteolysis / Filiz Civril and Karl-Peter Hopfner -- Isolation of RIG-I-associated RNAs from virus-infected cells / Andreas Schmidt ... [et al.] -- Structure modeling of Toll-Like Receptors / Jing Gong and Tiandi Wei -- Nucleic acid recognition in dendritic cells / Alexander Heiseke, Katharina Eisenächer, and Anne Krug -- Viral nucleic acid recognition in human nonimmune cells : in vitro systems / Andrea Ribeiro and Markus Wörnle -- Analysis of nucleic acid-induced nonimmune cell death in vitro / Simone Romoli and Adriana Migliorini -- In vitro analysis of nucleic acid recognition in B lymphocytes / Saskia Ziegler and Isabelle Bekeredjian-Ding -- Mapping of optimal CD8 T cell epitopes / Julia Roider, Thomas Vollbrecht, and Rika Draenert -- Modular approach to suppression assays : TLR ligands, conditioned medium, and viral infection / Viktor H. Koelzer and David Anz -- MicroRNA methodology : advances in miRNA technologies/ Theresa Kaeuferle ... [et al.] -- Expression profiling by real-time quantitative polymerase chain reaction (RT-qPCR) / Maciej Lech and Hans-Joachim Anders -- Evaluating the role of nucleic acid antigens in murine models of systemic lupus erythematosus / Amanda A. Watkins, Ramon G. B. Bonegio, and Ian R. Rifkin -- Induction and analysis of nephrotoxic serum nephritis in mice / John M. Hoppe and Volker Vielhauer -- Isolation of intratumoral leukocytes of TLR-stimulated tumor-bearing mice / Moritz Rapp, David Anz, and Max Schnurr -- Bifunctional siRNAs for tumor therapy / Fanny Matheis and Robert Besch.
  • 2012 Springer
    Rong-Fu Wang, editor.
    "There has been major growth in understanding innate immune signaling, inflammation, immune suppression and cancer immunotherapy. Innate immune regulation and cancer immunotherapy highlights emerging research about the underlying mechanisms of innate immunity and signaling regulation, inflammation and immune suppression that promote or inhibit cancer development and progression, and offers novel ideas and strategies to develop therapeutic cancer drugs or cell therapy by manipulating or blocking these negative signaling pathways and generating potent antitumor immunity. Recent studies have identified key innate immune receptors or sensors, novel signaling molecules and immune regulatory molecules that control immune responses, inflammation and immune suppression in cancer and other diseases. Major progresses in understanding of tumor antigens, immune suppressive molecules and cell population and novel vaccine strategies bring therapeutic cancer vaccines and drugs in realty. With chapters written by internationally recognized contributors, this book provides essential introduction and guide for immunologists, basic, translational and clinical cancer researchers."--Publisher's website.
  • 2008 Springer Protocols
    edited by Jonathan Ewbank and Eric Vivier.
    ENU mutagenesis in mice / Philippe Georgel ... [et al.] -- Innate immunity genes as candidate genes : searching for relevant natural polymorphisms in databases and assessing family-based association of polymorphisms with human diseases / Pascal Rihet -- KIR locus polymorphisms : genotyping and disease association analysis / Maureen P. Martin and Mary Carrington -- Experimental model for the study of the human immune system : production and monitoring of "human immune system" Rag2-/[gamma]c-/- mice / Nicolas Legrand, Kees Weijer, and Hergen Spits -- Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes / Kristina Vintersten ... [et al.] -- Bioluminescence imaging to evaluate infections and host response in vivo / Pamela Reilly Contag -- Intravital two-photon imaging of natural killer cells and dendritic cells in lymph nodes / Susanna Celli, Béatrice Breart, and Philippe Bousso -- Dissection of the antiviral NK cell response by MCMV mutants / Stipan Jonjic ... [et al.] -- Analyzing antibody-Fc-receptor interactions / Falk Nimmerjahn and Jeffrey V. Ravetch -- The isolation and identification of murine dendritic cell populations from lymphoid tissues and their production in culture / David Vremec and Ken Shortman -- Analysis of individual natural killer cell responses / Wayne M. Yokoyama and Sungjin Kim -- Isolation and analysis of human natural killer cell subsets / Guido Ferlazzo -- Innate immune function of eosinophils : from antiparasite to antitumor cells / Fanny Legrand ... [et al.] -- Ex vivo and in vitro primary mast cells / Michel Arock ... [et al.] -- Murine macrophages : a technical approach / Luisa Martinez-Pomares and Siamon Gordon -- Clinical analysis of dendritic cell subsets : the dendritogram / Anne Hosmalin, Miriam Lichtner, and Stéphanie Louis -- Clinical analysis of human natural killer cells / Pascale André and Nicolas Anfossi -- Lentiviral transduction of immune cells / Louise Swainson ... [et al.] -- Axenic mouse model / Antoine Giraud -- In vivo analysis of zebrafish innate immunity / Jean-Pierre Levraud ... [et al.] -- Reverse genetics analysis of antiparasitic responses in the malaria vector, Anopheles gambiae / Stephanie A. Blandin and Elena A. Levashina -- Drosophila immunity : methods for monitoring the activity of toll and Imd signaling pathways / Yves Romeo and Bruno Lemaitre -- Investigating the involvement of host factors involved in intracellular pathogen infection by RNAi in Drosophila cells / Hervé Agaisse -- Models of Caenorhabditis elegans infection by bacterial and fungal pathogens / Jennifer R. Powell and Frederick M. Ausubel -- Genetic analysis of Caenorhabditis elegans innate immunity / Michael Shapira and Man-Wah Tan -- Measuring cell-wall-based defenses and their effect on bacterial growth in Arabidopsis / Min Gab Kim and David Mackey.
  • 2013 Karger
    volume editors, Gunther Hartmann, Hermann Wagner.
    Microbiota's influence on immunity / Honda, K. ... [et al.] -- Inflammasomes and mucosal immune response / Elinav, E., Henao-Mejia, J., Flavell, R.A. -- Microbial endocrinology : an evolution-based shared mechanism determining microbiota's influence on health and disease / Lyte, M. -- Standing guard : innate lymphoid cells promote immunity and tissue homeostasis at barrier surface / Monticelli, L.A., Artis, D. -- miRNAs that shape the innate immune system : regulation through toll-like receptor signaling / Curtis, A.M., O'Neill, L.A. -- Type 2 diabetes and islet inflammation / Donath, M.Y. -- The innate immune system in Alzheimer's disease / Becker, H., Halle, A. -- Role of inflammasomes in obesity / Dixit, V.D. -- Gut-brain communication in the regulation of system metabolism / Miller, T.D., Pfliger, P.T., and Tschip, M.H. -- Metabolism and innate immunity : FOXO regulation of antimicrobial peptides in drosophila / Loch, G. ... [et al.] -- Dendritics cells orchestrate innate immunity agains bacterial kidney infection / Tittel, A.P. ... [et al.].
  • 2008 Springer
    edited by Holger Heine.
    Evolution of resistance genes in plants / Shunyuan Xiao, Wenming Wang, Xiaohua Yang -- The path less explored: innate immune reactions in Cnidarians / Thomas C. G. Bosch -- Bug versus bug : humoral immune responses in Drosophila melanogaster / Deniz Ertürk-Hasdemir ... [et al.] -- Cellular immune responses in Drosophila melanogaster / Adrienne Ivory, Katherine Randle, Louisa Wu -- Immune reactions in the vertebrates' closest relatives, the urochordates / Konstantin Khalturin, Ulrich Kürn, Thomas C. G. Bosch -- Innate immune system of the zebrafish, Danio rerio / Con Sullivan, Carol H. Kim -- Toll-like receptors in the mammalian innate immune system / Andrei E. Medvedev, Stefanie N. Vogel -- NLRs : a cytosolic armory of microbial sensors linked to human diseases / Mathias Chamaillard -- Antimicrobial peptides as first-line effector molecules of the human innate immune system / Regine Gläser, Jürgen Harder, Jens-Michael Schröder -- The complement system in innate immunity / K. R. Mayilyan ... [et al.].
  • 2012 Springer
    Selene Baschieri, editor.
    Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination. Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may result ineffective and, above all, may
  • 2007 ScienceDirect
    edited by David A. Cheresh.
    Also available: Print – 2007
  • 2014 Springer
    Magdalena Klink, editor.
    The tumor environment is a dynamic network that includes cancer cells, immune cells, fibroblasts, endothelial cells, extracellular matrix, cytokines and receptors. The aim of this book is to summarize the role of these components, especially immune cells, in tumor suppression and/or progression and describe in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for scientists and medical doctors working and/or lecturing in the field of cancer research and immunology.
  • 2007 Springer
    Paula M. Pitha, ed.
    Also available: Print – 2007
  • 2005 Springer Protocols
    edited by Daniel J.J. Carr.
    Also available: Print – 2005
  • 2014 Springer
    Simon Fillatreau, Anne O'Gara, editors.
    " This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date."--Publisher's website.
  • 2014 ScienceDirect
    Arseniy E. Yuzhalin, Anton G. Kutikhin.
    Introduction : basic concepts -- Interleukin-1 superfamily and cancer -- Interleukin-2 superfamily and cancer -- Interleukin-3, Interleukin-5, and cancer -- IL-6 family and cancer -- Interleukin-10 superfamily and cancer -- Interleukin-12 superfamily and cancer -- Interleukin-17 superfamily and cancer -- The rest of interleukins -- Concluding remarks.
  • 2012 Springer
    Marcel B.M. Teunissen, editor.
    Understanding the murine cutaneous dendritic cell network to improve intradermal vaccination strategies -- Insight into the immunobiology of human skin and functional specialization of skin dendritic cell subsets to innovate intradermal vaccination design -- Delivery systems for intradermal vaccination -- Targeting skin dendritic cells to improve intradermal vaccination -- Intradermal rabies vaccination : the evolution and future of pre- and post-exposure prophylaxis -- Intradermal vaccination to protect against yellow fever and influenza -- The dermis as a portal for dendritic cell-targeted immunotherapy of cutaneous melanoma -- DNA vaccines and intradermal vaccination by DNA tattooing
  • 2013 Springer
    Bryan R. Cullen, editor.
    The APOBEC3 Family of Retroelement Restriction Factors / Eric W. Refsland, Reuben S. Harris -- Inhibition of Retroviral Replication by Members of the TRIM Protein Family / Adam J. Fletcher, Greg J. Towers -- The Antiviral Activities of Tetherin / Stuart J. D. Neil -- Restriction of Retroviral Infection of Macrophages / Mark Sharkey -- Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors / Welkin E. Johnson -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants / György Szittya, József Burgyán -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates / Arabinda Nayak, Michel Tassetto, Mark Kunitomi, Raul Andino -- Roles of MicroRNAs in the Life Cycles of Mammalian Viruses / Eva Gottwein -- Interplay Between DNA Tumor Viruses and the Host DNA Damage Response / Karyn McFadden, Micah A. Luftig.
  • 2012 ScienceDirect
    Jorge H. Daruna.
    Historical antecedents -- Immune system basics -- Endocrine-immune modulation -- Neuroimmune modulation -- Stress, contextual change, and disease -- Psychosocial stress: neuroendocrine and immune effects -- Infection, allergy, and psychosocial stress -- Cancer, autoimmunity, and psychosocial stress -- Immune activity and psychopathology -- Immune function enhancement -- Integration and implications.
  • 2005 CRCnetBASE
    edited by Helen Tryphonas, Michel Fournier, Barry R. Blakley ... [et al.].
    Also available: Print – 2005
  • 2005 Springer
    by Gideon Berke and William R. Clark.
    Also available: Print – 2005
  • 2003 NCBI Bookshelf
    Mary Carrington, Paul Norman.
  • 2005 Springer
    Klaus Eichmann.
  • 2013 Springer
    Awanish Kumar.
    Leishmania-related illnesses remain among the world s deadliest neglected tropical diseases, affecting approximately 12 million people in 88 countries. The mortality rate is substantial, contributing to nearly two million disability-adjusted life years. As more is understood about this parasite and its effects, work toward prevention, control, and treatment continues apace. Leishmania and Leishmaniasis will address the parasite and its attendant disease, which manifests in three syndromes: Visceral (VL), Cutaneous (CL) and Mucocutaneous Leishmaniasis (ML). The morphology and life cycles of the various species will be among the topics addressed in Part One. Part Two will focus on immunology, including host-immune response to Leishmania infection, cross-immunity between the different species and adoptive transfer of immunity. Parts Three and Four will address how Leishmania invade and survive, the clinical features of the disease, and its diagnosis. Drugs, vaccines and treatment will be thoroughly explored, including experimental models of therapeutics. Leishmania and Leishmaniasis will provide a thorough examination of a parasite, the illnesses it causes and the misery it continues to visit upon large segments of the population.
  • 2015 Springer
    Ben Adler, Editor.
    This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world?s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis.
  • 2012 Springer Protocols
    edited by Robert B. Ashman.
    ENU-based phenotype-driven screening / Vera M. Ripoll, Philip L. Kong, and Paul K. Potter -- Detection and quantification of cytokines and other biomarkers / Evan L. Chiswick ... [et al.] -- Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells / Valérie Barbier ... [et al.] -- Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo / Valérie Barbier ... [et al.] -- Analyzing cell death events in cultured leukocytes / Karin Christenson, Fredrik B. Thorén, and Johan Bylund -- Towards a four-dimensional view of neutrophils / Ben A. Croker, Andrew W. Roberts, and Nicos A. Nicola -- Isolation of human and mouse neutrophils ex vivo and in vitro / Yan Hu -- Measurement of oxidative burst in neutrophils / Yu Chen and Wolfgang G. Junger -- Measurement of neutrophil elastase, proteinase 3, and cathepsin G activities using intramolecularly quenched fluorogenic substrates / Brice Korkmaz ... [et al.] -- The macrophage / Chris P. Verschoor, Alicja Puchta, and Dawn M.E. Bowdish -- Generation and characterization of MacGreen mice, the CFS1R-EGFP transgenic mice / R. Tedjo Sasmono and Elizabeth Williams -- Generation of mouse bone marrow-derived macrophages / Silvia Manzanero -- Isolation and differentiation of monocytes-macrophages from human blood / Dipti Vijayan -- In vitro measurement of phagocytosis and killing of Cryptococcus neoformans by macrophages / André Moraes Nicola and Arturo Casadevall -- Measuring the inflammasome / Olaf Gross -- Arginine and macrophage activation / Mònica Comalada -- Immunodetection of granzyme B tissue distribution and cellular localisation / Catherina H. Bird ... [et al.] -- Detection of human and mouse granzyme B activity in cell extracts / Sarah Elizabeth Stewart ... [et al.] -- T cell transfer model of colitis : a great tool to assess the contribution of T cells in chronic intestinal inflammation / Rajaraman Eri, Michael A. McGuckin, and Robert Wadley -- Measurement of nitrite in urine by gas chromatography-mass spectrometry / Dimitrios Tsikas ... [et al.].
  • 2016 Springer
    edited by Dieter Steinhilber, editor.
    Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.
    Also available: Print – 2016
  • 2003 Karger
    volume editors: Udo R. Markert, Peter Elsner.
    Also available: Print – 2003
  • 2015 Springer
    Mieczyslaw Pokorski, editor.
    Lung cancer and autoimmune diseases are complex entities in that they involve gene disturbance, gene polymorphism, and impaired gene repair mechanisms. The volume focuses on altered gene expression in tumor processes and in chronic autoimmune disorders. The chapters discuss the biological rationale for novel disease protein markers, present relevant clinical results, and give some diagnostic and therapeutic tips.
    Also available: Print – 2015
  • 2011 Springer
    Stefan E. Pambuccian, Ricardo H. Bardales.
    Introduction -- Overview of ancillary methods in lymph node FNA diagnosis -- Lymphadenopathy: anatomic and clinical clues to fine needle aspiration diagnosis -- Cytology of normal/reactive lymph nodes -- Overall assessment of the aspirate: diagnostic clues -- Overview of the algorithmic pattern-based approach to lymph node FNA -- The polymorphous lymphoid cell pattern -- The monotonous small-cell pattern -- The monotonous intermediate-sized cell pattern -- The monotonous large cell pattern -- The pleomorphic cell pattern -- Infectious and noninfectious lympadenitis -- Unusual neoplastic and nonneoplastic conditions of lymph nodes -- Pitfalls and limitations of FNA of lymph nodes.
  • 2008 Springer
    Lawrence Tretbar ... [et al.].
  • 2011 Springer
    Byung-Boong Lee, John Bergan, Stanley G. Rockson, editors.
    Primary Lymphedema as a Truncular Lymphatic Malformation -- Primary Lymphedema and Klippel-Trénaunay Syndrome -- Special Issues in Pediatric Primary Lymphedema -- Medical Management -- Surgical Management -- Epidemiology -- Etiology and Pathophysiology -- Clinical Overview-Diagnosis and Management -- Genetic Prospects for Lymphedema Management -- Breast Cancer -- Lower Extremity Cancers -- Radiation Complications -- Pathophysiology of Phlebolymphedema and a Physiologic Approach to Chronic Veno-lymphatic Insufficiency' -- Diagnosis and Management of Primary Phlebolymphedema -- Diagnosis and Management of Secondary Phlebolymphedema -- Management of Phlebolymphedema Ulcers -- Lymphedema Management by the Therapists -- Education of the Patient -- Patient/Family Advocacy -- Reimbursement of CDT-based Care -- General Considerations -- Etiology and Classification of Lymphatic Disorders -- Hereditary and Familial Lymphedema -- Embryology of the Lymphatic System and Lymphangiogenesis -- Anatomy of the Lymphatic System and Its Disorders -- Physiology, Pathophysiology, and Lymphodynamics: General Overview -- Lymphedema -- Physiology, Biology, and Lymph Biochemistry -- Physiology - Lymph Flow -- Pathology and Histochemistry -- Clinical Diagnosis: General Overview -- Clinical Staging -- Combined Clinical and Laboratory (Lymphoscintigraphic) Staging -- Early Diagnosis in Latent Phase -- Review of National and International Consensuses on Chronic Lymphedema -- Differential Diagnosis - General Considerations -- Differential Diagnosis - Lipedema -- Laboratory/Imaging Diagnosis: General Guidelines -- Radionuclide Lymphoscintigraphy -- Duplex Ultrasonography -- Combined Role of Lymphoscintigraphy, X-Ray Computed Tomography, Magnetic Resonance Imaging, and Positron Emission Tomography in the Management of Lymphedematous Disease -- Oil Contrast Lymphangiography -- Fluorescent Microlymphangiography -- Alternative Assessment and Measurement Tools -- Infection -- Physiological Principles of Physiotherapy -- Complete Decongestive Therapy -- Manual Lymph Drainage (Földi Method) -- Manual Lymph Drainage (Leduc Method) -- Compression Therapy -- Intermittent Pneumatic Compression Therapy -- Other Contemporary Treatment Modalities -- Medical Treatment -- Lower Limb Lymphedema -- Upper Limb Lymphedema -- Head and Neck Lymphedema -- Genital Lymphedema -- Psychological Aspect: Compliance and Quality of Life -- General Overview - Historical Background -- General Principles and Indications -- Lymphatic-Venous Derivative and Reconstructive Microsurgery -- Lymphatic-Lymphatic Reconstructive Microsurgery -- Lymph Node-Venous Microvascular Reconstructive Surgery: Filariasis Lymphedema -- Lymph Nodes Transfer Microvascular Reconstructive Surgery -- Current Dilemmas and Controversy -- Prospects for Lymphatic Reconstructive Surgery -- Historical Background - General Overview -- General Principles -- Contemporary Indications and Controversies -- Surgical Treatment of Postmastectomy Lymphedema - Liposuction -- Epilogue.
  • 2015 Springer
    Arin K. Greene, Sumner A. Slavin, Håkan Brorson, editors.
    This volume is a clinically-oriented book that can be used for patient care, teaching, or research. It covers the entire field of lymphedema, including both primary and secondary disease, as well as all diagnostic and treatment modalities. The text begins with a foundation for the condition, including its pathophysiology, epidemiology, and morbidity. Next, the classification of lymphedema is covered which is the template for accurate diagnosis. Clinical, radiological, and differential diagnosis of lymphedema is also reviewed. Finally, conservative and operative management is presented, including both physiologic and excisional procedures. Lymphedema: Presentation, Diagnosis, and Treatment provides a comprehensive, easy-to-read reference for any health care provider managing a patient with lymphedema. The text is clinically-focused, evidence-based, and practical. The reader, regardless of his/her level of training or specialty, will be able to adequately treat a patient with lymphedema using this resource. To facilitate its use in clinical settings, the book was designed to be portable. In addition, diagnostic and treatment algorithms are included to further simplify the management of these patients. Patient images are presented throughout the text to illustrate the clinical care of lymphedema. All chapters are written by experts in the field, and contain the most current information on the topic.
  • 2006 Springer
    Raffaele Badolato, Silvano Sozzani, editors.
    Also available: Print – 2006
  • 2013 Springer Protocols
    edited by Ralf Küppers.
    Origin and pathogenesis of B cell lymphomas / Marc Seifert, René Scholtysik, and Ralf Küppers -- Flow cytometry for non-Hodgkin and classical Hodgkin lymphoma / David Wu, Brent L. Wood, and Jonathan R. Fromm -- Laser-based microdissection of single cells from tissue sections and PCR analysis of rearranged immunoglobulin genes from isolated normal and malignant human B cells / Ralf Küppers, Markus Schneider, and Martin-Leo Hansmann -- PCR-based analysis of rearranged immunoglobulin or T-cell receptor genes by genescan analysis or heteroduplex analysis for clonality assessment in lymphoma diagnostics / Elke Boone, Brenda Verhaaf, and Anton W. Langerak -- Expression cloning of human B cell immunoglobulins / Hedda Wardemann and Juliane Kofer -- Studying the replication history of human B lymphocytes by real-time quantitative (RQ)-PCR / Menno C. van Zelm, Magdalena A. Berkowska, and Jacques J.M. van Dongen -- Detection of chromosomal translocations involving the immunoglobulin loci in B-cell malignancies / Martin J.S. Dyer -- Stereotyped B cell receptors in B cell leukemias and lymphomas / Nikos Darzentas and Kostas Stamatopoulos -- Flow cytometric MRD detection in selected mature B-cell malignancies / Sebastian Böttcher, Matthias Ritgen, and Michael Kneba -- MRD Detection in B-cell non-hodgkin lymphomas using Ig gene rearrangements and chromosomal translocations as targets for real-time quantitative PCR / Christiane Pott [and others] -- Enrichment of methylated DNA by methyl-CpG immunoprecipitation / Miriam Sonnet [and others] -- Gene expression profile analysis of lymphomas / Katia Basso and Ulf Klein -- FISH and FICTION to detect chromosomal aberrations in lymphomas / Maciej Giefing and Reiner Siebert -- Identification of pathogenetically relevant genes in lymphomagenesis by shRNA library screens / Vu N. Ngo -- Studying microRNAs in lymphoma / Joost Kluiver, Izabella Slezak-Prochazka, and Anke van den Berg -- Molecular methods of virus detection in lymphoma / Ruth F. Jarrett, Alice Gallagher, and Derek Gatherer -- High-throughput RNA sequencing in B-cell lymphomas / Wenming Xiao [and others].
  • 2014 Cambridge
    edited by Robert Marcus, John W. Sweetenham, Michael E. Williams.
    Epidemiology / Eve Roman and Alexandra G. Smith -- Prognostic factors for lymphomas / Guillaume Cartron and Philippe Solal-Celigny -- Imaging / Heok K. Cheow and Ashley S. Shaw -- Clinical trials in lymphoma / Thomas M. Habermann and Matthew Maurer -- Hodgkin lymphoma / Stephanie Sasse and Andreas Engert -- Follicular lymphoma / Kristian Bowles, Daniel Hodson, and Robert Marcus -- MALT and other marginal zone lymphomas / Emanuele Zucca and Francesco Bertoni -- Small lymphocytic lymphoma/chronic lymphocytic leukemia / Peter Hillmen -- Waldenstrom's macroglobulinemia/lymphoplasmacytic lymphoma / Steven P. Treon and Giampaolo Merlini -- Mantle cell lymphoma / Martin Dreyling and Michael E. Williams -- Burkitt and lymphoblastic lymphoma : clinical therapy and outcome / Nirali N. Shah, Alan S. Wayne, and Wyndham H. Wilson -- Therapy of diffuse large B-cell lymphoma / John W. Sweetenham -- Central nervous system lymphomas / Andres J.M. Ferreri and Lisa M. DeAngelis -- T-cell non-Hodgkin lymphoma / Sheetal M. Kircher [and others] -- Primary cutaneous lymphoma / Sean Whittaker -- Lymphoma in the immunosuppressed / Michele Spina [and others] -- Atypical lymphoproliferative, histiocytic, and dentritic cell disorders / Matthew S. Davids and Jennifer R. Brown.
  • 2014 CRCnetBASE
    editors, Gary C. Howard and Matthew R. Kaser.
    "This second edition provides guidance on all aspects of how to make and use antibodies for research, and commercial and industrial applications. All chapters are revised, updated, or expanded. New material in the book includes western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present descriptions of basic methods for making and using antibodies and describe basic laboratory techniques in detail. Each chapter includes introductory material, allowing for a better understanding of each concept. Practical examples are also included"--Provided by publisher.
  • 2002 Karger
    volume editors, Peter Perlmann, Marita Troye-Blomberg.
    pt. 1. Malaria parasites and disease -- Structure and life cycle / H. Fujioka -- Malaria parasites and the Anopheles mosquito /G. Dimopoulos -- Malaria: pathogenicity and disease / M. English -- pt. 2. Malaria antigens -- Sporozoite antigens: biology and immunology of the circumsporozoite protein and thrombospondin-related anonymous protein / P. Sinnis -- Immune responses to liver-stage parasites: implications for vaccine development / M.R. Hollingdale -- Merozoite antigens involved in invasion / K. Berzins -- Asexual blood stages of malaria antigens: cytoadherence / D.I. Baruch -- Rosetting and autoagglutination in Plasmodium falciparum / V. Fernandez -- Sexual and sporogonic stage antigens / R.W. Sauerwein -- pt. 3. Malaria infection: immunity and regulation -- Mouse models of blood-stage malaria infections: immune responses and cytokines involved in protection and pathology / J. Langhorne -- Malaria and the immune system in humans / P. Perlmann -- Genetic regulation of malaria infection in humans / M. Troye-Blomberg -- pt. 4. Malaria vaccines -- Pre-erythrocytic malaria vaccines to prevent Plasmodium flaciparum malaria / W.R. Ballou -- Vaccines against asexual stage malaria parasites / S. Kumar -- Transmission-blocking vaccines / D.C. Kaslow -- Nucleic acid vaccines against malaria / D.L. Doolan -- Antidisease vaccines / L. Schofield -- Adjuvants and malaria vaccine development / L. Xiao -- Malaria vaccine trials / B. Greenwood.
    Also available: Print – 2002
  • 2007 CRCnetBASE
    edited by Clare Mills, Harry Wichers and Karin Hoffmann-Sommergruber.
    pt. 1. What are food allergens and allergies? -- pt. 2. Allergens in foods - from raw to processed foods -- pt. 3. Assessing allergic risks and practical management of allergens in food.
  • 2002 Ovid
    edited by Daniel C. Adelman, Thomas B. Casale, Jonathan Corren.
    Also available: Print – 2002
  • 2012
    editors, Daniel C. Adelman, Thomas B. Casale, Jonathan Corren.
    Status: Not Checked OutLane Catalog Record
    Introduction to the immune system / Lori Broderick, Taylor A. Doherty, and David Broide -- Immediate hypersensitivity : approach to diagnosis / Sarbjit S. Saini and Nkiruka Erekosima -- Aeroallergens and environmental factors / William Neaville, Robert Ausdenmoore, and Robert K. Bush -- Rhinitis / Candace Bouler Anz and Mark S. Dykewicz -- Sinusitis, nasal polyps, and otitis media / Ricardo A. Tan and Jonathan Corren -- Immunotherapy for inhalant allergens / Harold S. Nelson -- Allergic and immunologic disorders of the eye / Leonard Bielory -- Asthma diagnosis / Stephen C. Lazarus -- Asthma treatment / Joel M. Hartman ... [et al.] -- Immunologic diseases of the lung / Shefalee Amin, Michelle Zeidler, and Eric Kleerup -- Atopic dermatitis and contact dermatitis / Mark Boguniewicz, Marcella Aquino, and Luz Fonacier -- Urticaria and angioedema / Jeffrey R. Stokes and Mark H. Moss -- Anaphylaxis / Phil Lieberman and Debendra Pattanaik -- Insect allergy / David B. K. Golden -- Drug allergy / David A. Khan -- Allergic and non-allergic reactions to food / Stephen R. Boden and A. Wesley Burks -- Eosinophilic gastrointestinal disorders / Terri F. Brown-Whitehorn ... [et al.] -- Primary immunodeficiency diseases / Shradha Agarwal and Charlotte Cunningham-Rundles -- Approach to the patient with recurrent infections / Zuhair K. Ballas -- Diagnostic immunology / Thomas A. Fleisher, Joao Bosco Oliveira, and Jack J. H. Bleesing -- Adverse responses to vaccines / John M. Kelso -- Complementary medicine in allergy and immunology / Timothy Ryan Mainardi and Leonard Bielory -- Building related illness / Jessica Savage and Robert A. Wood.
  • 2013 Cambridge
    Joseph H. Antin, Harvard Medical School and Dana-Farber Brigham and Women's Cancer Center, Boston, MA, Deborah Yolin Raley, Dana-Farber Brigham and Women's Cancer Center, Boston, MA.
    1. Rationale for transplantation -- 2. Types of transplantation -- 3. Human leukocyte antigen matching in allogeneic transplantation -- 4. Stem cell source -- 5. Pre-transplant evaluation and counseling of patient and donor -- 6. Conditioning regimens -- 7. Stem cell infusion -- 8. ABO compatibility -- 9. Engraftment -- 10. Preventative care -- 11. Transplant-related complications -- 12. Overview of acute and chronic graft-versus-host disease -- 13. Acute graft-versus-host disease and staging -- 14. Graft-versus-host prophylactic regimens -- 15. Treatment guidelines for acute graft-versus-host disease -- 16. Chronic graft-versus-host disease -- 17. Engraftment syndrome -- 18. Infectious disease -- 19. Graft rejection and failure -- 20. Gastrointestinal complications -- 21. Oral health in stem cell transplantation -- 22. Pulmonary complications -- 23. Veno-occlusive disease -- 24. Special transfusion-related situations -- 25. Cardiovascular complications -- 26. Neurologic complications -- 27. Cystitis -- 28. Donor lymphocyte infusion -- 29. Transplantation: regulation and accreditation -- Index.
  • 2006 Springer
    S.A. Plotkin (ed).
    Mass Vaccination: When and Why / D. L. Heymann and R. B. Aylward -- Mass Vaccination and Surveillance/Containment in the Eradication of Smallpox / J. M. Lane -- Mass Immunization Programs: Principles and Standards / J. D. Grabenstein and R. L. Nevin -- Immunization Campaigns in the UK / K. Noakes and D. Salisbury -- Diphtheria / C. R. Vitek -- Universal Mass Vaccination against Hepatitis A / F. E. André -- Mass Vaccination against Hepatitis B: the French Example / F. Denis and D. Levy-Bruhl -- Mass Vaccination for Annual and Pandemic Influenza / B. Schwartz and P. Wortley -- Is Global Measles Eradication Feasible? / C. A. de Quadros -- Measles Aerosol Vaccination / J. L. Valdespino-Gómez, M de Lourdes Garcia-Garcia, J. Fernandez-de-Castro, A. M. Henao-Restrepo, J. Bennett, and J. Sepulveda-Amor -- Mass Vaccination Campaigns for Polio Eradication: an Essential Strategy for Success / R. W. Sutter and C. Maher -- Rubella Mass Campaigns / S. Reef -- Mass Vaccination to Control Epidemic and Endemic Typhoid Fever / M. M. Levine -- Mass Vaccination: Solutions in the Skin / G. M. Glenn and R. T. Kenney.
    Also available: Print – 2006
  • 2011 Springer
    Domenico Ribatti, Enrico Crivellato.
    Mast cells are versatile, tissue-homing secretory cells, which were first described by Paul Ehrlich in 1878. Mast cells have long been implicated in the pathogenesis of allergic reactions and certain protective responses to parasites. Their functional role, however, has been discovered to be increasingly complex and multifarious. Mast cells have been implicated in various cell-mediated immune reactions, being found in tissues from multiple disease sites, and as a component of the host reaction to bacteria, parasite, and even virus infections. They have also been shown to participate to angiogenic and tissue repair processes after injury. The importance of a possible functional link between chronic inflammation and cancer has long been recognized. As most tumours contain inflammatory cell infiltrates, which often include plentiful mast cells, the question as to the possible contribution of mast cells to tumour development has progressively been emerged. In this book, the general biology of these cells, their development, anatomical distribution and phenotype as well as their secretory products will first be discussed. The biology of tumour cells, their structural and molecular characteristics, the specificity of the tumour microenvironment and the development of a vascular network in the tumour context will be analyzed. The involvement of mast cells in tumour biology and tumour fate will then be considered, with particular emphasis on the capacity of these cells to stimulate tumour growth by promoting angiogenesis and lymphangiogenesis. The last chapter suggest that mast cells may serve as a novel therapeutic target for cancer treatment.
  • 2005 Karger
    volume editors: Hirohisa Saito, Yoshimichi Okayama.
    Also available: Print – 2005
  • 2011 Springer
    Carmen Molina-París, Grant Lythe, editors.
    Preface -- Thymocyte development -- A review of mathematical models for T cell receptor triggering and antigen discrimination -- Dynamic tuning of T cell receptor specificity by co-receptors and costimulation -- T cell activation and function: role of signal strength -- The cyton model for lymphocyte proliferation and differentiation -- Modeling itravital two-photon data of lymphocyte migration and interaction -- Modeling lymphocyte dynamics in vivo -- Continuous-time birth and death processes: diversity maintenance of naïve T cells in the periphery -- Multivariate competition processes: a model for two competing T cell clonotypes -- Stochastic modeling of T Cell homeostasis for two competing clonotypes via the master equation -- Dendritic cell migration in the intestinal tract -- Reassessing germinal center reaction concepts -- B cell strategies of Ag recognition in a stratified immune system -- Dynamics of Peripheral regulatory and effector T cells competing for antigen presenting cells -- Mathematical models of the role of IL-2 in the interactions between helper and regulstory CD4+ T cells -- A Physicist{u2019}s approach to immunology -- Timescales of the adaptive immune response -- Using mathematical models to explore the role of cytoxic T lymphocytes in HIV infection -- Viral immunity and persistence -- Index.
  • 2009 Springer
    Diane E. Griffin, Michael B.A. Oldstone, editors.
    Making it to the synapse : measles virus spread in and among neurons / V.A. Young and G.F. Rall -- Modeling subacute sclerosing panencephalitis in a transgenic mouse system : uncoding pathogenesis of disease and illuminating components of immune control / M.B.A. Oldstone -- Measles studies in the macaque model / R.L. de Swart -- Ferrets as a model for morbillivirus pathogenesis, complications, and vaccines / P. Pillet, N. Svitek and V. von Messling -- Current animal models : cotton rat animal model / S. Niewiesk -- Current animal models : transgenic animal models for the study of measles pathogenesis / C.I. Sellin and B. Horvat -- Molecular epidemiology of measles virus / P.A. Rota, D.A. Featherstone, and W.J. Bellini -- Human immunology of measles virus infections / D. Naniche -- Measles control and the prospect of eradication / W.J. Moss -- Measles : old vaccines, new vaccines / D.E. Griffin and C.-H. Pan -- Measles virus for cancer therapy / S.J. Russell and K.W. Peng -- Measles virus-induced immunosuppression / S. Schneider-Schaulies and J. Schneider-Schaulies -- Hostile communication of measles virus with host innate immunity and dendritic cells / B. Hahm.
    Also available: Print – 2009
  • 2005 ScienceDirect
    edited by Michael T. Lotze and Angus W. Thomson.
    MHC class I -- MHC class II -- Cytokine receptor heterogeneity -- Genetic diversity at human cytokine loci in health and disease -- Signaling molecules affecting immune response -- Toll-like receptors in innate immunity -- DNA sequence-specific transcription factors -- Genetic diversity in NK and NKT cells -- Handling sera and obtaining fluid from different compartments -- Acute-phase proteins and inflammation -- Complement in health and disease -- Immunoglobulin titers and immunoglobulin subtypes -- Human antiglobulin responses -- Rheumatoid factors -- Autoantibodies -- Antibody affinity using fluorescence -- SLE-associated tests -- Multiplexed serum assays -- Handling and storage of cells and sera: practical considerations -- Phenotypic and functional measurements on circulating immune cells and their subsets -- Natural killer cells -- Tetramer analysis -- Peripheral blood naive and memory B cells -- Dendritic cells -- Monocytes and macrophages -- Tumor cells -- Regulatory T cells -- Intracellular cytokine assays -- Cytolytic assays -- Mixed leukocyte reactions -- Antigen/mitogen-stimulated lymphocyte proliferation -- Monitoring cell death -- Cytokine enzyme linked immunosorbent spot (ELISPOT) assay -- Testing natural killer cells -- Delayed type hypersensitivity responses -- Rebuck windows: granulocyte function -- The vascular and coagulation systems -- Sentinel node assays -- Imaging inflammation -- Cancer - solid tumors -- Cancer - hematologic disorders -- Autoimmunity - rheumatoid arthritis -- Autoimmunity - type 1 diabetes -- Autoimmunity - systemic lupus erythematosus -- Autoimmunity - multiple sclerosis -- Autoimmunity - inflammatory bowel disease -- Autoimmunity - endocrine -- Autoimmunity - vasculitis -- Transplantation -- Viral responses - HIV-1 -- Viral responses - epstein-barr virus -- Viral responses - hepatitis -- Dermatology -- Arteriosclerosis -- Primary immunodeficiencies -- Asthma and allergy -- Serum proteomic profiling and analysis -- Imaging cytometry -- Cancer biometrics -- Genomics and microarrays -- Image informatics.
  • 2005 Karger
    volume editors: Dieter Kabelitz, Jens-Michael Schröder.
    Also available: Print – 2005
  • 2005 Springer
    edited by Sudhir Gupta, William E. Paul and Ralph Steinman.
    Also available: Print – 2005
  • 2007 Springer
    edited by Sudhir Gupta, Rafi Ahmed and Alan Sher.
    Also available: Print – 2007
  • 2011
    Peter S. Choi.
    Cancers arise through the acquisition of genetic and epigenetic changes which result in the activation of growth-promoting oncogenes and the inactivation of growth-inhibitory tumor suppressor genes. Despite the accumulation of many diverse mutations, some tumors exhibit sensitivity to the targeted inhibition of single gene products, in a phenomenon known as oncogene addiction. In the Emu-tTA/tetO-MYC transgenic mouse model, overexpression of MYC results in the development of aggressive T-cell lymphoma, and subsequent inactivation of MYC results in rapid tumor regression occurring primarily via cell cycle arrest, senescence, and apoptosis. This thesis presents work investigating various aspects of oncogene addiction in MYC-induced lymphomas. We have discovered that tumor recurrence in MYC-induced lymphomas following initial MYC inactivation occurs mainly through the persistence and expansion of cells that fail to suppress MYC expression. This demonstrates that addiction to some oncogenes may be inescapable and that resistance to MYC therapy would likely occur through the restoration of MYC function. We have also discovered that activation of the Wnt/beta-catenin pathway is a common secondary event in MYC-induced lymphomagenesis. Beta-catenin was found to be frequently stabilized due to mutations that prevent its phosphorylation and subsequent degradation, including a novel splice acceptor site mutation. Inhibition of beta-catenin resulted in robust apoptosis, indicating that MYC-induced lymphomas can exhibit addiction to multiple different oncogenes.
  • 2001 CRCnetBASE
    edited by Gabriel Virella.
    Also available: Print – 2001
  • 2014 Springer
    Yann Meunier.
    This book outlines risk assessments for 28 diseases and medical conditions including the following aspects: genetics, biochemistry, serology, past medical history, family history, co-morbidities, age, gender, ethnicity, nutrition and lifestyle. Recommendations are made for how to avoid, eliminate or mitigate risks. Preventing measures concerning chemical compound intake, lifestyle and nutrition are proposed. The unique content and approach of the book to chronic disease management make it a state-of-the-art reference work, addressing a missing component of medical care and reflecting the cutting edge of preventive medicine.
  • 2012 CRCnetBASE
    edited by Ronald Ross Watson.
    "This new edition presents information on how melatonin is synthesized and produced in the body as well as how this hormone affects several diseases. The book heavily focuses on prevention as well as treatment of various human disease states including behavior disorders, mental disorders, breast cancer, bone health, and gastrointestinal diseases. It covers the role of melatonin in the prevention of oxidative stress, mutagenesis, sun damage, ocular health, gut motility, and detoxification. It also presents mechanisms of melatonin action in humans including cell modulation, signaling mechanisms, protective effects, and melatonin receptors as well as its role as an antioxidant"--Provided by publisher.
  • 2010 Springer
    edited by Maurizio Zanetti, Stephen P. Schoenberger.
    Memory TH1/TH2 cell generation controlled by Schnurri-2 / Toshinori Nakayama and Motoko Y. Kimura -- Transcriptional regulation during CD8 T-cell immune responses / Ivana Munitic ... [et al.] -- The role of interleukin-2 in memory CD8 cell differentiation / Onur Boyman, Jae-Ho Cho and Jonathan Sprent -- The role of inflammation in the generation and maintenance of memory T cells / Noah S. Butler and John T. Harty -- The role of OX40 (CD134) in T-cell memory generation / Andrew D. Weinberg -- The role of precursor frequency in the differentiation of memory T cells : memory by numbers / Amanda L. Marzo, Ryan T. Sowell and Bernadette Scott -- CD8 T-cell memory differentiation during acute and chronic viral infections / Vandana Kalia, Surojit Sarkar and Rafi Ahmed -- Longevity of T-cell memory following acute viral infection / Joshua M. Walker and Mark K. Slifka -- Principles of memory CD8 T-cells generation in relation to protective immunity / Maurizio Zanetti, Paola Castiglioni and Elizabeth Ingulli -- Memory T cells in rhesus macaques / Monica Vaccari and Genoveffa Franchini -- Memory T-cell subsets in parasitic infections / Sara Colpitts and Phillip Scott -- Antigen specific memory T cells and their putative need for the generation of sustained anti-tumor responses / Kory L. Alderson and William J. Murphy -- Memory T-cell responses and survival in human cancer : remember to stay alive / Matthieu Camus and Jérôme Galon -- Analysis of vaccine-induced T cells in humans with cancer / Stefanie L. Slezak ... [et al.] -- Memory T-cell homeostasis and senescence during aging / Sian M. Henson and Arne N. Akbar.
    Also available: Print – 2010
  • 2001 CRCnetBASE
    Rafael Fernandez-Botran, Václav Větvička.
  • 2010 ClinicalKey
    edited by Jeffrey K. Aronson.
    Drugs Used in Cancer Chemotherpy -- Corticosteroids and Prostaglandins -- Cytokines and Cytokine Modulators Interferons -- Monoclonal Antibodies -- Immune Modulators.
  • 2013 Springer
    Natalia Aptsiauri, Angel Miguel Garcia-Lora, Teresa Cabrera.
    Overview of MHC Class I Antigens -- HLA Class I Expression in Human Cancer -- MHC Class I Expression in Experimental Mouse Models of Cancer: Immunotherapy of Tumors with Different MHC-I Expression Patterns -- Potential Therapeutic Approaches for Increasing Tumor Immunogenicity by Upregulation of Tumor HLA Class I Expression -- Conclusions.
  • 2008 Springer
    Andreas Bosio, Bernhard Gerstmayer, editors.
    Also available: Print – 2008
  • 2009 Karger
    editors, Per Brandtzaeg, Erika Isolauri, Susan L. Prescott.
    A paradigm for commensalism : the role of a specific microbial polysaccharide in health and disease / Kasper, D.L. -- The hygiene hypothesis : do we still believe in it? / Björkstén, B. -- "ABC" of mucosal immunology / Brandtzaeg, P. -- Innate and adaptive immune pathways to tolerance / Thornton, C.A., Morgan, G. -- Hitting the mucosal road in tolerance induction / Wiedermann, U. -- Obesity : extending the hygiene hypothesis / Isolauri, E. ... [et al.] -- Autoimmunity and diet / Cerf-Bensussan, N. -- Eosinophilic esophagitis : example of an emerging allergic manifestation? / Heine, R.G. -- Microbial-host interactions in inflammatory bowel diseases and experimental colitis / Sartor, R.B. -- Development and regulation of immune responses to food antigens in pre- and postnatal life / Renz, H. ... [et al.] -- Novel approaches in treating food allergy using allergens / Rancé, F. -- Allergen avoidance approaches in food allergy management / Koletzko, S., Koletzko, B. -- Role of dietary immunomodulatory factors in the development of immune tolerance / Prescott, S.L. -- Microbial host interactions : selecting the right probiotics and prebiotics for infants / Salminen, S. ... [et al.] -- Probiotics and prebiotics : immunological and clinical effects in allergic disease / Tang, M.L.K. -- Modified proteins in allergy prevention / von Berg, A.
  • 2015 Springer
    Catherine M. Greene, editor.
    The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohnℓ́ℓs disease, diabetes), and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new therapeutic targets, this volume will also be of interest to industrial biomedical researchers and those involved in drug development.
    Also available: Print – 2015
  • 2010 Springer Protocols
    edited by Silvia Monticelli.
    A rapid, quantitative assay for direct detection of microRNAs and other small RNAs using splinted ligation -- Normalization of microRNA quantitative RT-PCR data in reduced scale experimental designs -- MicroRNA detection in bone marrow cells by LNA-FISH -- Measuring microRNA expression in size-limited facs-sorted and microdissected samples -- MicroRNA cloning from cells of the immune system -- High-throughput profiling in the hematopoietic system -- Construction of small RNA cDNA libraries for deep sequencing -- MicroRNA-profiling in formalin-fixed paraffin-embedded specimens -- Expression of miRNAs in lymphocytes : A review -- Mouse models for miRNA expression: The ROSA26 locus -- Regulation of monocytopoiesis by microRNAs -- MicroRNA activity in B lymphocytes -- Isolation and characterization of microRNAs of human mature erythrocytes -- Stable overexpression of miRNAs in bone marrow-derived murine mast cells using lentiviral expression vectors -- Monitoring microRNA activity and validating microRNA targets by reporter-based approaches -- Lentivirus-mediated antagomir expression -- Solution structure of miRNA:mRNA complex -- MiRNA editing -- Computational prediction of microRNA targets -- Large-scale integration of microRNA and gene expression data for identification of enriched microRNA-mRNA associations in biological systems -- Identification and validation of the cellular targets of virus-encoded microRNAs.
  • v. 1-2., 2009
    [edited by] N. Franklin Adkinson, Jr. ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2014 ClinicalKey
    Adkinson, N. Franklin; Middleton, Elliott.
  • 2017 ClinicalKey
    Robyn E. O'Hehir, Stephen T. Holgate, Aziz Sheikh.
    Introduction to mechanisms of allergic diseases -- The origins of allergic disease -- Epidemiology of allergic diseases -- Indoor and outdoor allergens and pollutants -- Principles of allergy diagnosis -- Allergen-specific immunotherapy -- Asthma -- Allergic rhinitis and conjunctivitis -- Drug allergy -- Urticaria and angioedema without wheals -- Atopic dermatitis and allergic contact dermatitis -- Food allergy and gastrointestinal syndromes -- Anaphylaxis -- Occupational allergy -- Insect allergy.
  • 2005 Springer
    H. Singh and R. Grosschedl (ed.).
    Gene regulatory networks orchestrating B cell fate specification, commitment, and differentiation / K.L. Medina, H. Singh -- Helix-loop-helix proteins in lymphocyte lineage determination / B.L. Kee -- Ikaros-family proteins : in search of molecular functions during lymphocyte development / B.S. Cobb, S.T. Smale -- Biochemistry of V(D)J recombination / D.G. Schatz, E. Spanopoulou -- The pre-B cell receptor in B cell development : recent advances, persistent questions and conserved mechanisms / M.R. Clark ... [et al.] -- Transcriptional control of B cell activation / L.M. Corcoran -- Expression of MHC II genes / G. Drozina ... [et al.] -- Class switch recombination : an emerging mechanism / A.L. Kenter -- Blimp-1 ; Immunoglobulin secretion and the switch to plasma cells / R. Schiammas, M.M. Davis -- Wnt signaling in lymphopoiesis / A. Timm, R. Grosschedl.
    Also available: Print – 2005
  • 2014 Springer
    Falk Nimmerjahn, editor.
    This book focuses on the function of antibodies in vivo. Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. These new results dramatically changed our view of how antibodies function in vivo. The importance of this class of molecules is demonstrated by the heightened susceptibility to infections of humans and mice with an altered capacity to generate pathogen specific antibody responses. Thus, the majority of our currently available vaccines, such as vaccines against influenza, measles and hepatitis focus on the generation of long lasting antibody responses. Recent evidence from a variety of in vivo model systems and from human patient cohorts has highlighted the exclusive role of cellular Fc-receptors for certain immunoglobulin isotypes and subclasses. With the recent discovery of a human Fc-receptor for IgM all different human immunoglobulin isotypes now have a cellular receptor, providing a feedback mechanism and link between antibodies and the cellular components of the immune system. Moreover it has become clear the complement and Fc-receptor system are tightly connected and regulate each other to ensure a well balanced immune response. Among the immunoglobulin isotypes IgG plays a very important protective role against microbial infections and also as a therapeutic agent to kill tumor cells or autoantibody producing B cells in autoimmune disease. Transfer of our knowledge about the crucial function of Fc-receptors has led to the production of a second generation of therapeutic antibodies with enhanced binding to this class of receptors. Binding of antibodies to Fc-receptors leads to the recruitment of the potent pro-inflammatory effector functions of cells from the innate immune system. Hence, Fc-receptors link the innate and adaptive immune system, emphasizing the importance of both arms of the immune system and their crosstalk during anti-microbial immune responses. Besides this pro-inflammatory activity immunoglobulin G (IgG) molecules are long known to also have an anti-inflammatory function. This is demonstrated by the use of high dose intravenous immunoglobulins as a therapeutic agent in many human autoimmune diseases. During the past five years several new insights into the molecular and cellular pathways of this anti-inflammatory activity were gained radically changing our view of IgG function in vivo. Several lines of evidence suggest that the sugar moiety attached to the IgG molecule is responsible for these opposing activities and may be seen as a molecular switch enabling the immune system to change IgG function from a pro- to an anti-inflammatory activity. There is convincing evidence in mice and humans that aberrant IgG glycosylation could be an important new pathway for understanding the impaired antibody activity during autoimmune disease. Besides this tremendous increase in basic knowledge about factors influencing immunoglobulin activity the book will also provide insights into how these new insights might help to generate novel therapeutic approaches to enhance IgG activity for tumor therapy on the one hand, and how to block the self-destructive activity of IgG autoantibodies during autoimmune disease on the other hand.
  • 2005 Springer
    edited by Moncef Zouali.
    Also available: Print – 2005
  • 2011 Springer
    Albert M. Wu, editor.
    Part 1. Introduction to Glyco-Experiences -- Serendipity in Scientific Discoveries: Some Examples in Glycosciences / Yuan-Chuan Lee -- My 30-Year Devotion to the N-Linked Oligosaccharide Structures / Noriko Takahashi -- Part 2. Blood Group ABH/Le-related Antigens -- Human Blood Group ABH/Ii, Lea,b,x,y, and Sialyl Lea,x Glycotopes; Internal Structures; and Immunochemical Roles of Human Ovarian Cyst Glycoproteins / Albert M. Wu -- Lewis Glyco-Epitopes: Structure, Biosynthesis, and Functions / Hui-Li Chen -- A Unique Endo-β-Galactosidase that Cleaves Both Blood Group A and B Glycotopes / Su-Chen Li, Kimberly M. Anderson and Yu-Teh Li -- Part 3. Lectins -- Recognition Roles of Mammalian Structural Units and Polyvalency in Lectin-Glycan Interactions / Albert M. Wu, Jia-Haw Liu, Tanuja Singh and Zhangung Yang -- Adhesion/Growth-Regulatory Galectins: Insights into Their Ligand Selectivity Using Natural Glycoproteins and Glycotopes / Albert M. Wu, Tanuja Singh, Jia-Hau Liu, Sabine André and Martin Lensch, et al. -- Glycotope Structures and Intramolecular Affinity Factors of Plant Lectins for Tn/T Antigens / Pierre Rougé, Willy J. Peumans, Els J. M. Van Damme, Annick Barre and Tanuja Singh, et al. -- The Five Bacterial Lectins (PA-IL, PA-IIL, RSL, RS-IIL, and CV-IIL): Interactions with Diverse Animal Cells and Glycoproteins / Nechama Gilboa-Garber, Keren D. Zinger-Yosovich, Dvora Sudakevitz, Batya Lerrer and Anne Imberty, et al. -- On the Differential Sialic Acid Specificity of Lectins from Different Parts of Saraca indica / Bishnu P. Chatterjee and Mainak Majumder -- Regulation of Lectin Production by the Human Pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: Effects of Choline, Trehalose, and Ethanol / Nachman C. Garber, Keren D. Zinger-Yosovich, Dvora Sudakevitz, Itschak Axelrad and Nechama Gilboa-Garber -- Non-carbohydrate-Mediated Interaction of Lectins with Plant Proteins / Jared Q. Gerlach, Michelle Kilcoyne, Seron Eaton, Veer Bhavanandan and Lokesh Joshi -- Novel Concepts About the Role of Lectins in the Plant Cell / Els J. M. Van Dammes, Elke Fouquaert, Nausicaä Lannoo, Gianni Vandenborre and Dieter Schouppe, et al. -- Part 4. Structures and Functions of Glycolipids -- Role of Gangliosides and Plasma Membrane-Associated Sialidase in the Process of Cell Membrane Organization / Sandro Sonnino, Vanna Chigorno, Massimo Aureli, Anie Priscilla Masilamani and Manuela Valsecchi, et al. -- 9-O-Acetyl GD3 in Lymphoid and Erythroid Cells / Kankana Mukherjee, Suchandra Chowdhury, Susmita Mondal, Chandan Mandal and Sarmila Chandra, et al. -- GM3 Upregulation of Matrix Metalloproteinase-9 Possibly Through PI3K, AKT, RICTOR, RHOGDI-2, and TNF-A Pathways in Mouse Melanoma B16 Cells / Pu Wang, Xiaodong Wang, Peixing Wu, Jinghai Zhang and Toshinori Sato, et al. -- Pathological Roles of Ganglioside Mimicry in Guillain-Barré Syndrome and Related Neuropathies / Robert K. Yu, Toshio Ariga, Seigo Usuki and Ken-ichi Kaida -- Structure and Function of Glycolipids in Thermophilic Bacteria / Feng-Ling Yang, Yu-Liang Yang and Shih-Hsiung Wu -- Lipooligosaccharides of Neisseria Species: Similarity Between N. polysaccharea and N. meningitidis LOSs / Chao-Ming Tsai -- Part 5. Structures and Functions of Complex Carbohydrates -- Roles for N- and O-Glycans in Early Mouse Development / Suzannah A. Williams and Pamela Stanley -- Glycobiology in the Field of Gerontology (Glycogerontology) / Akira Kobata -- Galectins in Regulation of Apoptosis / Fu-Tong Liu, Ri-Yao Yang, Jun Saegusa, Huan-Yuan Chen and Daniel K. Hsu -- Avian and Human Influenza Virus Receptors and Their Distribution / Yasuo Suzuki -- Importance of a Factor VIIIc-Like Glycoprotein Expressed in Capillary Endothelial Cells (eFactor VIIIc) in Angiogenesis / Dipak K. Banerjee, Caroline M. Oliveira, José J. Tavárez, Viswa N. Katiyar and Subiman Saha, et al. -- Mucin O-Glycan Branching Enzymes: Structure, Function, and Gene Regulation / Pi-Wan Cheng and Prakash Radhakrishnan -- Studying Carbohydrate Self-Recognition in Marine Sponges Using Synthetic Aggregation Factor Epitopes / Johannis P. Kamerling and Adriana Carvalho de Souza -- Docking of Chitin Oligomers and Nod Factors on Lectin Domains of the LysM-RLK Receptors in the Medicago-Rhizobium Symbiosis / Pierre Rougé, Wim Nerinckx, Clare Gough, Jean-Jacques Bono and Annick Barre -- Part 6. Glycoimmunology -- O-Acetylated Sialic Acids and Their Role in Immune Defense / Roland Schauer, G. Vinayaga Srinivasan, Dirk Wipfler, Bernhard Kniep and Reinhard Schwartz-Albiez -- Sialylated and Sulfated Carbohydrate Ligands for Selectins and Siglecs: Involvement in Traffic and Homing of Human Memory T and B Lymphocytes / Reiji Kannagi, Katsuyuki Ohmori, Guo-Yun Chen, Keiko Miyazaki and Mineko Izawa, et al. -- Diversity of Natural Anti-α-Galactosyl Antibodies in Human Serum / Elwira Lisowska and Maria Duk -- Significance of Serum Glycoprotein Profiles in Spontaneous Tolerance After Liver Allograft Transplantation / Pei-Weng Wang and Tai-Long Pan -- Part 7. Glycobiology of Cancer -- Hematogenous Metastasis: Roles of CD44v and Alternative Sialofucosylated Selectin Ligands / Konstantinos Konstantopoulos and Susan N. Thomas -- Regulation of Glycosyltransferase Genes in Apoptotic Breast Cancer Cells Induced by l-PPMP and Cisplatin / Rui Ma, Elizabeth A. Hopp, N. Matthew Decker, Audrey Loucks and James R. Johnson, et al. -- Aberrant Glycosphingolipid Expression and Membrane Organization in Tumor Cells: Consequences on Tumor-Host Interactions / Alessandro Prinetti, Simona Prioni, Nicoletta Loberto, Massimo Aureli and Valentina Nocco, et al. -- Human KDN (Deaminated Neuraminic Acid) and Its Elevated Expression in Cancer Cells: Mechanism and Significance / Sadako Inoue, Ken Kitajima, Chihiro Sato and Shinji Go -- Polysialic Acid Bioengineering of Cancer and Neuronal Cells by N-Acyl Sialic Acid Precursor Treatment / Robert A. Pon, Wei Zou and Harold J. Jennings -- Part 8. Glyco Applications -- Synthesis of Hemagglutinin-Binding Trisaccharides / Cheng-Chung Wang, Suvarn S. Kulkarni, Medel Manuel L. Zulueta and Shang-Cheng Hung -- Fabrication and Applications of Glyconanomaterials / Po-Chiao Lin, Avijit Kumar Adak and Chun-Cheng Lin -- Glycan Arrays to Decipher the Specificity of Plant Lectins / Els J. M. Van Damme, David F. Smith, Richard Cummings and Willy J. Peumans -- Targeting C-Type Lectin for the Treatment of Flavivirus Infections / Szu-Ting Chen, Yi-Ling Lin, Ming-Ting Huang, Ming-Fang Wu and Shie-Liang Hsieh.
    Also available: Print – 2011
  • 2014 Springer
    edited by Hubert Hilbi.
    Legionnaires' disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.
  • 2009 Springer
    Chihiro Sasakawa, editor.
    Functional morphology of the gastrointestinal tract / L. Shen -- Vibrio cholerae interactions with the gastrointestinal tract: Lessons from animal studies / J.M. Ritchie and M.K. Waldor -- Interaction of Yersinia with the gut: Mechanisms of pathogenesis and immune evasion / P. Dube -- Molecular mechanisms of Salmonella virulence and host resistance / Y. Valdez, R.B.R. Ferreira and B.B. Finlay -- Virulence mechanisms and persistence strategies of the human gastric pathogen Helicobacter pylori / tW. Fischer, S. Prassl and R. Haas -- Listeria as an enteroinvasive gastrointestinal pathogen / S.B. Barbuddhe and T. Chakraborty -- Molecular mechanisms of Campylobacter infection / J.P.M. Putten ... [et al.] -- Shigella infection of intestinal epithelium and circumvention of the host innate defense system / H. Ashida ... [et al.].
    Also available: Print – 2009
  • 2010
    Jonathan Wiley Jones.
    Francisella tularensis is a facultative intracellular pathogen that causes the disease tularemia. The ability of F. tularensis to escape phagosomal degradation and replicate in the macrophage cytosol is central to its pathogenesis. The macrophage responds to the presence of cytosolic F. tularensis with the production of type-I interferons (IFN) and subsequent activation of the inflammasome. We conducted a forward genetic screen of a F. novicida transposon library to identify mutants that resulted in an increased or decreased cytosolic response in macrophages. We identified 164 F. novicida mutants that lead to increased type-I IFN production and inflammasome activation in macrophages. We also identified 74 mutants that resulted in decreased type-I IFN and inflammasome responses in macrophages. Finally, we identified AIM2 as the host receptor responsible for inflammasome activation in response to cytosolic F. novicida. We showed that lysing cytosolic F. novicida leads to release of bacterial DNA that triggers type-IFN through a pathway involving the adaptor STING. STING-dependent type-I IFN production increases the expression of AIM2, which complexes with the bacterial DNA and initiates inflammasome activation. We further demonstrate that AIM2 is critical for innate immunity to F. novicida infection in vivo. Thus we identified a novel bacterial ligand and novel cytosolic sensing components that play a role in the host defense to bacterial infections.
  • 2005 Springer
    M.B.A. Oldstone (ed.).
    Molecular mimicry, microbial infection, and autoimmune disease : evolution of the concept / M.B.A. Oldstone -- The structural interactions between T cell receptors and MHC-peptide complexes place physical limits on self-nonself discrimination / K.W. Wucherpfennig -- A virus-induced molecular mimicry model of multiple sclerosis / J.K. Olson, A.M. Ercolini, and S.D. Miller -- Suppression of autoimmunity via microbial mimics of altered peptide ligands / L. Steinman, P.J. Utz, and W.H. Robinson -- Molecular and cellular mechanisms, pathogenesis, and treatment of insulin-dependent diabetes obtained through study of a transgenic model of molecular mimicry / M.B.A. Oldstone -- Trypanosoma cruzi-induced molecular mimicry and Chagas' disease / N. Gironès, H. Cuervo, and M. Fresno -- HTLV-1 induced molecular mimicry in neurological disease / S.M. Lee ... [et al.] -- Molecular mimicry : anti-DNA antibodies bind microbial and nonnucleic acid self-antigens / J.S. Rice ... [et al.] -- Chlamydia and antigenic mimicry / K. Bachmaier and J.M. Penninger.
    Also available: Print – 2005
  • 2010
    Poornima Parameswaran.
    Small RNAs that are 19-30 nucleotides in length use the genetic information encoded in their sequence to effect gene regulation in a sequence-directed manner. Infections with RNA viruses in plants, worms and flies generate short viral-derived RNAs ("vsRNAs") that map to the genome of the infecting virus. The regulated production of these vsRNAs and their engagement by the immune apparatus is essential for inhibiting viral growth, making vsRNAs important components of antiviral immunity in these organisms. RNA virus-derived vsRNA-mediated gene silencing is yet to be demonstrated in mammalian systems. We investigated diverse RNA virus-mammalian systems, and characterized changes in small RNA populations that occur during viral infection in animal cells using high-throughput sequencing. Due to the large number of samples to be analyzed, we designed DNA barcodes to 'tag' RNA samples from individual experiments, which facilitated sequencing in parallel from multiple samples. Our work demonstrated the generality of RNA virus-derived vsRNA production, and the ability of the cellular short RNA apparatus to engage these vsRNAs in worms during Flock House Virus replication, and in mammalian cells during infections with Hepatitis C, Polio, Dengue, Vesicular Stomatitis or West Nile virus. In addition to the appearance of vsRNAs during infection, we saw a number of specific changes in host-encoded small RNA (miRNA) profiles. For several infection models investigated in more detail, the RNAi and Interferon pathways modulated the abundance of vsRNAs. We found evidence for populations of vsRNAs that exist as duplexed small interfering RNAs ("siRNAs; " effectors of gene silencing) with zero to three nucleotide 3' overhangs. We also observed strand-selective loading of siRNAs onto Argonaute complexes, which are mediators of gene silencing. We quantitated the capacity of these HCVrep-derived vsRNAs to down-regulate target mRNAs in a sequence-specific manner in mammalian systems. We found that abundant HCVrep vsRNAs are not capable of mediating robust silencing (i.e. 2-fold or higher) of Luciferase reporters that have been engineered with vsRNA targets. Additionally, over-expression of siRNAs corresponding to five abundant vsRNAs failed to enhance silencing of Hepatitis C Virus mRNA. These results complement each other and suggest that in mammalian hosts, the virus may coexist with an abundant population of vsRNAs. Questions still remain as to whether robust gene silencing may be achieved by the cooperative action of abundant vsRNAs, or if abundant vsRNAs specifically inhibited from functioning in gene silencing, or alternatively, if they have novel roles in pathways distinct from gene silencing.
  • 2013 Springer
    Matthias Giese, editor.
    This book gives a comprehensive overview to all aspects of global molecular vaccine research. It introduces concepts of vaccine immunology and molecular vaccine development for viral, bacterial, parasitic and fungal infections. Furthermore, the broad field of research and development in molecular cancer vaccines is discussed in detail. This book is a must have for scientists and clinicians interested in new developments in molecular vaccine research and application in infections and cancer.
  • 2014 Springer
    Matthias Giese, editor.
    This title discusses all aspects of non-infectious and non-cancer -- so called NINC -- vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine development. The way of novel vaccines from bench to preclinical to clinical studies and launch to the market under EMEA (European Medicines Agency) and FDA (Food and Drug Administration) guidelines are described in-depth. Practical perspectives of patentability of vaccines are discussed. The book is therefore of interest for researchers and clinicians engaged in vaccine development and molecular vaccine application.
  • 2013 Future Med
    editor, Fatih M. Uckun.
    Monoclonal antibodies in contemporary cancer therapy / Fatih M. Uckun -- mAbs targeting CD20 and other lymphocyte CD markers in lymphoma treatment / Letizia Polito, Rossella Mancuso, Daniele Mercatelli, Massimo Bortolotti & Andrea Bolognesi -- mAbs targeting CTLA-4 and clinical outcomes / Francesco Spagnolo, Virginia Picasso & Paola Queirolo -- mAbs targeting VEGF/VEGFR and clinical outcomes in cancer treatment / Brendan Curley, Michael Newton & Jame Abraham -- mAbs targeting RANKL in bone metastasis treatment / Bérengère Gobin, Marc Baud'Huin, Bertrand Isidor, Dominique Heymann & Marie-Françoise Heymann -- Novel mAb-based therapies for leukemia / Osmond J. D'Cruz & Fatih M. Uckun -- Index.
  • 2014 Springer Protocols
    edited by Vincent Ossipow, Nicolas Fischer.
    Antigen production for monoclonal antibody generation / Giovanni Magistrelli and Pauline Malinge -- Method for the generation of antibodies specific for site and posttranslational modifications / Hidemasa Goto and Masaki Inagaki -- Immunization, hybridoma generation, and selection for monoclonal antibody production / Hyung-Yong Kim, Alexander Stojadinovic, and Mina J. Izadjoo -- Hybridoma technology for the generation of rodent mAbs via classical fusion / Efthalia Chronopoulou [and three others] -- Generation of rabbit monoclonal antibodies / Pi-Chen Yam and Katherine L. Knight -- Screening hybridomas for cell surface antigens by high-throughput homogeneous assay and flow cytometry / Alejandro Uribe-Benninghoff [and four others] -- Screening and subcloning of high producer transfectomas using semisolid media and automated colony picker / Suba Dharshanan and Cheah Swee Hung -- Design and generation of synthetic antibody libraries for phage display / Gang Chen and Sachdev S. Sidhu -- Selection and screening using antibody phage display libraries / Patrick Koenig and Germaine Fuh -- Yeast surface display for antibody isolation : library construction, library screening, and affinity maturation / James A.Van Deventer and Karl Dane Wittrup -- Human B cell immortalization for monoclonal antibody production / Joyce Hui-Yuen, Siva Koganti, and Sumita Bhaduri-McIntosh -- Using next-generation sequencing for discovery of high- frequency monoclonal antibodies in the variable gene repertoires from immunized mice / Ulrike Haessler and Sai T. Reddy -- Cloning, reformatting, and small-scale expression of monoclonal antibody isolated from mouse, rat, or hamster hybridoma / Jeremy Loyau and François Rousseau -- Cloning of recombinant monoclonal antibodies from hybridomas in a single mammalian expression plasmid / Nicole Müller-Sienerth [and three others] -- Monoclonal antibody purification by ceramic hydroxyapatite chromatography / Larry J. Cummings, Russell G. Frost, and Mark A. Snyder -- Rapid purification of monoclonal antibodies using magnetic microspheres / Pauline Malinge and Giovanni Magistrelli -- Generation of cell lines for monoclonal antibody production / Krista Alvin and Jianxin Ye -- Expression and purification of recombinant antibody formats and antibody fusion proteins / Martin Siegemund [and four others] -- Purification of antibodies and antibody fragments using CaptureSelect [trademark] affinity resins / Pim Hermans, Hendrik Adams, and Frank Detmers -- Reformatting of scFv antibodies into the scFv-Fc format and their downstream purification / Emil Bujak [and three others] -- Antibody V and C domain sequence, structure, and interaction analysis with special reference to IMGT® / Eltaf Alamyar [and three others] -- Measuring antibody affinities as well as the active concentration of antigens present on a cell surface / Palaniswami Rathanaswami -- Determination of antibody structures / Robyn L. Stanfield -- Affinity maturation of monoclonal antibodies by multi-site- directed mutagenesis / Hyung-Yong Kim, Alexander Stojadinovic, and Mina J. Izadjoo -- Epitope mapping with membrane-bound synthetic overlapping peptides / Terumi Midoro-Horiuti and Randall M. Goldblum -- Epitope mapping by epitope excision, hydrogen/deuterium exchange, and peptide-panning techniques combined with in silico analysis/ Nicola Clementi [and five others] -- Fine epitope mapping based on phage display and extensive mutagenesis of the target antigen / Gertrudis Rojas -- Epitope mapping with random phage display library / Terumi Midoro-Horiuti and Randall M. Goldblum -- Epitope mapping of monoclonal and polyclonal antibodies using bacterial cell surface display / Anna-Luisa Volk, Francis Jingxin Hu, and Johan Rockberg -- Ion exchange-high-performance liquid chromatography (IEX-HPLC) / Marie Corbier, Delphine Schrag, and Sylvain Raimondi -- Size exclusion-high-performance liquid chromatography (SEC-HPLC) / Delphine Schrag, Marie Corbier, and Sylvain Raimondi -- N-glycosylation characterization by liquid chromatography with mass spectrometry / Song Klapoetke -- Fc engineering of antibodies and antibody derivatives by primary sequence alteration and their functional characterization / Stefanie Derer [and six others] -- Labeling and use of monoclonal antibodies in immunofluorescence : protocols for cytoskeletal and nuclear antigens / Christoph R. Bauer -- Generation and use of antibody fragments for structural studies of proteins refractory to crystallization / Stephen J. Stahl, Norman R. Watts, and Paul T. Wingfield -- Antibody array generation and use / Carl A.K. Borrebaeck and Christer Wingren.
  • 2007. Springer Protocols
    edited by Maher Albitar.
  • 2014 Wellcome Trust
    edited by E.M. Jones and E.M. Tansey.
  • 2013 Springer Protocols
    edited by Irving C. Allen.
    Transgenic Mouse Models -- Pulmonary Antigen Presenting Cells: Isolation, Purification, and Culture -- Evaluation of T Cell Function in Allergic Disease -- Evaluating B-Cells: From Bone Marrow Precursors to Antibody Producing Cells -- Protocols for Identifying, Enumerating and Assessing Mouse Eosinophils -- Evaluation of Classical, Alternative, and Regulatory Functions of Bone Marrow-Derived Macrophages -- Applications of Mouse Airway Epithelial Cell Culture for Asthma Research -- Isolation and Characterization of Mast Cells in Mouse Models of Allergic Diseases -- Purifying and Measuring Immunoglobulin E (IgE) and Anti-IgE -- Protocols for the Induction and Evaluation of Systemic Anaphylaxis in Mice -- Contact Hypersensitivity Models in Mice -- Induction of Allergic Rhinitis in Mice -- Induction of Allergic Airway Disease Using House Dust Mite Allergen -- An Inhalation Model of Allergic Fungal Asthma: Aspergillus fumigatus-Induced Inflammation and Remodeling in Allergic Airways Disease -- PAMPs and DAMPs in Allergy Exacerbation Models -- Assessment of Airway Hyperresponsiveness in Mouse Models of Allergic Lung Disease Using Detailed Measurements of Respiratory Mechanics -- Bilateral Vagotomy as a Tool for Determining Autonomic Involvement in Airway Responses in Mouse Models of Asthma -- Clara Epithelial Cell Depletion in the Lung -- A Mouse Model for Evaluating the Contribution of Fibrocytes and Myofibroblasts to Airway Remodeling in Allergic Asthma -- Assessment of Airway Hyperresponsiveness in Murine Tracheal Rings -- Use of the Cockroach Antigen Model of Acute Asthma to Determine the Immunomodulatory Role of Early Exposure to Gastrointestinal Infection -- Expression Profiling to Identify Candidate Genes Associated with Allergic Phenotypes -- Flow Cytometric Methods for the Assessment of Allergic Disease -- Generation of Bone Marrow and Fetal Liver Chimeric Mice.
  • 2013 Springer Protocols
    edited by Irving C. Allen.
    The innate immune system represents a critical arm of the immune response by providing immediate and robust host defense; however, human studies of its function are often limited by ethical, logistical, and technical obstacles. In Mouse Models of Innate Immunity: Methods and Protocols, experts in the field explore the design and execution of experiments used to thoroughly evaluate critical elements associated with the host innate immune response. The volume opens with methods that are essential for collecting and assessing various primary cells that are highly relevant to innate immunity, and it continues with in vivo protocols commonly used to evaluate the innate immune response in the mouse, including mouse models of respiratory infection, gastrointestinal inflammation, fungal and parasitic diseases, sepsis, and HIV-1 infection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Mouse Models of Innate Immunity: Methods and Protocols will serve the research community by providing expert advice and protocols that allow both experienced and novice investigators to successfully plan, implement, and assess disease processes associated with the innate immune response.
  • 2007 Springer
    edited by Charlotte Slayton Kaetzel.
  • 2006 Springer
    Stephen K. Tyring (ed.).
    The role of mucosal immunity in protection against viral diseases / Vandana Madkan, Karan Sra, and Stephen K. Tyring -- Anogenital mucosal immunology and virology / Anthony Simmons -- Gastrointestinal mucosal immunology / David A. Bland, Carlos A. Barrera, and Victor E. Reyes -- Virology of the gastrointestinal tract / Richard L. Ward ... [et al.] -- Oral manifestations of viral diseases / Denis P. Lynch -- Common respiratory viruses and pulmonary mucosal immunology / David B. Huang -- Ophthalmic manifestations of viral diseases / Steven Yeh and Mitchell P. Weikert.
  • 2013 Springer
    Alice Prince, editor.
    In contrast to the substantial literature that focuses upon innate immune signaling in the gut, there is remarkably less known about the response of the airway to bacterial pathogens. The purpose of this book will be to review the current status of theunderstanding of the pathogenesis of acute bacterial pneumonia, slanted toward the mucosal immunology of these infections. It will describe, in general, the signaling cascades that control the proinflammatory response to bacterial infection in the lung. How innate immune signaling is orchestrated in response to specific common airway pathogens is addressed, targeting Staphylococus aureus (including MRSA), Streptococcus pneumoniae and Klebsiella pneumoniae. By describing the general immunological responses to conserved bacterial components and then detailing how specific organisms cause infection, this book provides a targeted but comprehensive review of this important topic.
  • 2005 ScienceDirect
    edited by Jiri Mestecky, Michael E. Lamm, Jerry R. McGhee ... [et al.].
    Also available: Print – v. 1-2, 2005.
  • 2012 Springer
    Pamela A. Kozlowski, editor.
    Most human pathogens utilize mucosal surfaces to access the host. This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the sublingual immunization route, which may offer a safer alternative to the nasal route for induction of broadly disseminated immune responses. External host defenses that inhibit entry of microorganisms at mucosal surfaces also pose obstacles to the efficient internalization of mucosally-applied vaccines. Transcutaneous immunization with appropriate adjuvants and permeation enhancers can induce mucosal immune responses and may be advantageous for bypassing these luminal barriers. Other chapters describe strategies for enhancing uptake of mucosal vaccines, for instance through targeted delivery to antigen-sampling M cells, construction of virus-like particles which mimic natural pathogens, addition of mucoadhesives or formulation as nanoparticles. Topics include edible vaccines as well as plant-based production of subunit or particulate vaccines that could be administered by any route. Dry powder vaccines that could be insufflated or directly applied to mucosal surfaces may be particularly ideal for mass vaccination in developing countries. The manufacture, stability and efficacy of powder formulations is comprehensively reviewed. We conclude with chapters on two of the greatest challenges facing mucosal vaccine development: human immunodeficiency virus and bioterrorist agents. This monograph highlights progress and information that should prove invaluable for the development of contemporary vaccines that prevent infection by these and other mucosal pathogens.
  • 2012 Springer
    [edited by] Zhong-Shan Gao, Hua-Hao Shen, Min Zheng, Lynn J. Frewer, Luud J.W.J. Gilissen.
    Part I. General Allergy. Prevalence of Allergic Diseases in China / Huan Qian, Min Zheng -- Mechanism of Type I Hypersensitivity / Cheng Zhou -- Multidisciplinary Approaches to Allergy Prevention / Luud J.W.J. Gilissen, Zhong-Shan Gao, Zhi Chen -- Part II. Allergenic Sources and Allergens. Overview of Allergen Sources in China / Zhao-Wei Yang, Zhong-Shan Gao, Ying-Tao Ma [and others] -- Allergen Protein Families and Cross-Reactivity / Luud J.W.J. Gilissen, Zhong-Shan Gao -- Seafood Allergens in China and Anti-allergenic Property of Seaweeds / Zhen-Xing Li, Hong Lin -- Food Allergen Epitopes / Hong-Bing Chen, Jin-Yan Gao -- Recombinant Allergens and Applications / Ying-Tao Ma, Zhao-Wei Yang, Zhong-Shan Gao -- Part III. Diagnosis. The CREATE Project: Development of Certified Reference Materials for Allergenic Products and Validation of Methods for Their Quantification / R. van Ree, M.D. Chapman, F. Ferreira [and others] -- Diagnosis of Skin Allergy Diseases / Huan Qian, Min Zheng -- Novel Approaches for the In-Vitro Diagnosis of Type I Allergies / Margrit Fooke -- Influence of Food Processing, Digestion and the Food Matrix on Allergenicity & Cellular Measures of Allergenicity / Y.M. Vissers, H.J. Wichers, H.F.J. Savelkoul -- Part IV. Therapies and Pharmacy. Immunotherapy of Asthma: From Basic Research to Clinical Practices / Hui-Ying Wang, Hua-Hao Shen -- Pharmacotherapy in Common Allergic Diseases / Erina M. Lin -- Immunotherapy in Allergic Skin Disease / Hao Cheng -- Traditional Chinese Medicine for Treating Food Allergy and Associated Eczema: From Research to Practice Perspective / Xiu-Min Li -- Immunomodulation by Food / Ingrid van der Meer, Jurriaan Mes, Amrah Weijn, Harry Wichers -- Prospective Studies on Mite (Dermatophagoides farinae) Allergen Immunotherapy in China / Ting-Huan Wen -- The Influence of Pollen Concentration on the Dispension of Antihistaminics and Corticosteroids to Hay Fever Patients / Arnold J.H. van Vliet, Hilde Tobi -- Part V. Hypoallergenic Products. In Search of Hypoallergenic Birch Trees: Characterization of PR-10 Genes from Eight Betula Species and Detection of Bet v 1 Isoforms in Birch Pollen Using a Combined Genomics- Proteomics Approach / M.J.M. Smulders, Martijn F. Schenk, Luud J.W.J. Gilissen -- Hypoallergenic Soybean, from Genes to Cultivar / Rong-Xia Guan, Xu-Qian Fang, Ru-Zhen Chang, Li-Juan Qiu -- Fruit Allergy and Genetic and Genomic Tools to Select Hypoallergenic Fruit Cultivars / Zhong-Shan Gao, Zhao-Wei Yang, Luud Gilissen -- Creating Hypoallergenic Crops through Genetic Modification / Xing-Jun Wang, Han Xia, Shuan-Tao Liu [and others] -- Acceptance of Natural and Genetically Modified Hypoallergenic Apples by Consumers with an Oral Allergy Syndrome (OAS) / I.M. van der Meer, M.F. Schenk, A.R.H. Fischer [and others] -- Cow's Milk Allergens and Technologies to Control Allergenicity / Yong-Kang Luo, Guan-Hao Bu -- Part VI Environment, Hygiene and Societal Issues. Prevalence of Asthma and Asthmatic Symptoms in Children in Relation to Environmental Factors --Epidemiological Studies in School Children in Taiyuan, China / Zhuo-Hui Zhao, Zhuan-Hua Wang, Zheng Zhang [and others] -- The Relationship of Food Allergies and Respiratory Allergies in Urban and Rural Chinese Children / Gary W.K. Wong, Yu-Zhi Chen, Jing Li, Nan-Shan Zhong -- Socio-Economic Issues Associated with Food Allergy / L.J. Frewer, J. Voordouw, M.F. Schenk [and others] -- The Association between Helminth Infections and Atopic Diseases / L.A.H. Hermsen.
  • 2006 Springer
    Sadik Tuzun, Elizabeth Bent, editors.
  • 2013 Springer
    Takashi Yamamura, Bruno Gran, editors.
    The availability of powerful genome-wide association study technology, during the last five years, has shown that most of the "new" MS susceptibility loci are immune-response genes. It is clear that there is much novelty in the field of MS immunology, which has served as an impetus to invest in new therapies. Notably, most if not all of these are immunotherapies. Even the equally exciting field of cell-based therapies and neuro-regeneration may well rely on cells or growth factors that are no less immunomodulators than restorative of myelin and neural cell function. Multiple Sclerosis Immunology looks at MS immunology as the basis for the present and-even more-the future of treatments for this complex autoimmune condition. Both editors are immunologists, as well as clinical neurologists, and appreciate the importance of a sustained dialogue between basic and clinical scientists to ensure that "translation" is real and not just virtual.
  • 2015 Springer Protocols
    edited by Robert Weissert.
    Positional gene cloning in experimental populations / Maja Jagodic and Pernilla Stridh - - Generation of transgenic rats using lentiviral vectors / Holger M. Reichard and Henrike J. Fischer -- DNA vaccination techniques / Nicolas Fissolo, Xavier Montalban, and Manuel Comabella -- Peripheral blood mononuclear cells : isolation, freezing, thawing, and culture / Christine Riedhammer, Dagmar Halbritter, and Robert Weissert -- ELISPOT techniques / Niannian Ji and Thomas G. Forsthuber -- Isolation of central nervous system (CNS) infiltrating cells / Ilgiz A. Mufazalov and Ari Waisman -- Methods for ex vivo analysis of immune cell function from the central nervous system / Darryl G. Turner ... [et al.] -- Neurofilament light chain determination from peripheral blood samples / Marguerite Limberg ... [et al.] -- Detection of autoantibodies against myelin oligodendrocyte glycoprotein in multiple sclerosis and related diseases / Melania Spadaro and Edgar Meinl -- Myelinating cultures : an in vitro tool to identify demyelinating and axopathic autoantibodies / Maren Lindner and Christopher Linington -- In vivo visualization of (auto-) immune processes in the central nervous system of rodents / Christian Schlager ... [et al.] -- Optical coherence tomography to assess neurodegeneration in multiple sclerosis / Axel Petzold -- Experimental autoimmune encephalomyelitis in mice / Rachael L. Terry, Igal Ifergan, and Stephen D. Miller -- Actively induced experimental autoimmune encephalomyelitis in rats / Robert Weissert -- Experimental autoimmune encephalomyelitis in marmosets / S. Anwar Jagessar ... [et al.]-- Neuropathological techniques to investigate CNS pathology in experimental autoimmune encephalomyelitis (EAE) / Karin Steinbach and Doron Merkler -- Neuropathological techniques to investigate central nervous system sections in multiple sclerosis / Jan Bauer and Hans Lassmann.
  • 2014 ScienceDirect
    Diana Boraschi and Albert Duschl.
    Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage.
  • v. 1-3, 2008-2010. Springer
    v. 2, 2009 Springer
    v. 3, 2010 Springer
    edited by Vassil St. Georgiev, Karl A. Western, John J. McGowan.
    v. 1. Frontiers in research -- v. 2. Impact on Global Health -- v. 3. Intramural research.
  • 2005 ScienceDirect
    volume editors, Lóránd Bertók, Donna A. Chow.
  • 2016 Springer
    Eric Vivier, James Di Santo, Alessandro Moretta, editors.
    Transcriptional control of NK cells -- Development, homeostasis, and heterogeneity of NK cells -- Diversification and functional specialization of human NK cell subsets -- Dynamic regulation of NK cell responsiveness -- NK cells and cancer immunoediting -- Sweet is the memory of past troubles: NK cells remember -- Lessons from NK cell definiencies in the mouse -- Probing human NK cell biology using human immune system (HIS) mice -- Haploidentical haematopoietic stem cell transplantation: role of NK cells and effect of cytomegalovirus infections -- The past, present, and future of NK cells in hematopoietic cell transplantation and adoptive transfer -- Index.
  • 2010 Springer
    Jacques Zimmer, editor.
  • 2012 Springer
    Masaki Terabe, Jay A. Berzofsky, editors.
    Introduction : mechanisms of NKT-cell-mediated adjuvant activity and function of iPS-derived NKT cells / Masaru Taniguchi ... [et al.] -- Structure and recognition of antigens for invariant NKT cells / Bo Pei and Mitchell Kronenberg -- Invariant NKT cell-based vaccine strategies / John-Paul Jukes ... [et al.] -- Immune regulation of tumor immunity by NKT cells / Jessica J. O'Konek, Jay A. Berzofsky, and Masaki Terabe -- The regulation of CD1d+ and CD1d- tumors by NKT cells : the roles of NKT cells in regulating CD1d+ and CD1d- tumor immunity / Jianyun Liu, Gourapura J. Renukaradhya, and Randy R. Brutkiewicz -- DC-based immunotherapy targeting NKT cells / Shin-ichiro Fujii and Kanako Shimizu -- Therapeutic approaches utilising NKT cells / Stephen R. Mattarollo and Mark J. Smyth -- NKT cells or cancer patients and how models can inform therapeutic plans / Mark A. Exley, Lydia Lynch, and Michael Nowak -- Understanding the role of natural killer T cells in hematologic malignancies : progress and challenges / Natalia Neparidze and Madhav V. Dhodapkar -- Clinical trials with alpha-galactosylceramide (KRN7000) in advanced cancer / Famke L. Schneiders ... [et al.] -- Clinical trials of invariant natural killer T cell-based immunotherapy for cancer / Shinichiro Motohashi, Yoshitaka Okamoto, and Toshinori Nakayama.
  • 2006 Springer
    edited by Gad Loebenstein and John Peter Carr.
  • 2012 Springer
    edited by Hans U. Lutz.
    Naturally occurring IgM antibodies to oxidation-specific epitopes / Christoph J. Binder -- Naturally occurring autoantibodies to apoptotic cells / Keith B. Elkon and Gregg J. Silverman -- Naturally occurring antibodies directed against carbohydrate tumor antigens / Reinhard Schwartz-Albiez -- Naturally occurring antibodies as therapeutics for neurologic disease : can human monoclonal IgMs replace the limited resource IVIG? / Arthur E. Warrington ... [et al.] -- Nature and nurture of catalytic antibodies / Sudhir Paul ... [et al.] -- Naturally occurring autoantibodies in mediating clearance of senescent red blood cells / Hans U. Lutz -- Naturally occurring autoantibodies against ss-amyloid / Jan-Philipp Bach and Richard Dodel -- Multi-faceted role of naturally occurring autoantibodies in fighting pathogens / Hicham Bouhlal and Srini Kaveri -- Immunoregulation by naturally occurring and disease-associated autoantibodies : binding to cytokines and their role in regulation of T-cell responses / Claus H. Nielsen and Klaus Bendtzen -- Modulation of dendritic cells and regulatory T cells by naturally occurring antibodies / Jaap Kwekkeboom -- Control of B cells expressing naturally occurring autoantibodies / Jean Louis Pasquali and Thierry Martin -- Granulocyte death regulation by naturally occurring autoantibodies / Stephan Von Gunten and Hans-Uwe Simon -- Naturally occurring autoantibodies mediate ischemia/reperfusion-induced tissue injury / Sherry D. Fleming -- How immune complexes from certain IgG NAbs and any F(ab')2 can mediate excessive complement activation / Hans U. Lutz -- The natural autoantibody repertoire in newborns and adults : a current overview / Asaf Madi ... [et al.] -- Antibody polyspecificity : what does it matter? / Jordan D. Dimitrov, Anastas D. Pashov, Tchavdar L. Vassilev -- Positive and negative selection of natural autoreactive B cells / Richard R. Hardy and Kyoko Hayakawa -- Naturally occurring antibodies/autoantibodies in polyclonal immunoglobulin concentrates / Peter J. Späth and Hans U. Lutz.
    Also available: Print – 2012
  • 2011 Springer
    [editors] Rafi Ahmed, Tasuku Honjo, Editors.
    TIM-3 and its regulatory role in immune responses / Chen Zhu, Ana C. Anderson and Vijay K. Kuchroo -- Role of PD-1 in regulating T-cell immunity / Hyun-Tak Jin, Rafi Ahmed and Taku Okazaki -- The role of IL-10 in regulating immunity to persistent viral infections / Elizabeth B. Wilson and David G. Brooks -- Inhibitory Ly49 receptors on mouse natural killer cells / Mark T. Orr and Lewis L. Lanier -- Immunoregulatory roles for Fc receptor-like molecules / Götz R.A. Ehrhardt and Max D. Cooper -- Fc[gamma]Rs in health and disease / Falk Nimmerjahn and Jeffrey V. Ravetch -- TGF-[beta] function in immune suppression / Akihiko Yoshimura and Go Muto.
  • 2012 Springer Protocols
    edited by Myron Christodoulides.
    Neisseria meningitidis: biology, microbiology, and epidemiology -- Classification and pathogenesis of meningococcal infections -- Detection of Neisseria meningitidis in cerebrospinal fluid using a multiplex PCR and the luminex detection technology -- Generating knock-out and complementation strains of Neisseria meningitidis -- Identification and functional characterization of sRNAs in Neisseria meningitidis -- Expression, purification, and crystallization of neisserial outer membrane proteins -- Genome-scale metabolic models: reconstruction and analysis -- TMT labelling for the quantitative analysis of adaptive responses in the meningococcal proteome -- Meningococcal ligands and molecular targets of the host -- In vivo imaging of meningococcal disease dynamics -- Methods for studying Neisseria meningitidis biofilms -- Laminar-flow chamber assay for measuring bacterial adhesion under shear stress -- Techniques to measure pilus retraction forces -- Human dendritic cell culture and bacterial infection -- Hydrogen-deuterium exchange coupled to mass spectrometry to investigate ligand-receptor interactions -- Visualising PAMP-PRR interactions using nanoscale imaging -- Transcriptome analyses in the interaction of Neisseria meningitidis with mammalian host cells -- Use of the pan-Neisseria microarray and experimental design for transcriptomics studies of Neisseria -- Analysis of parameters associated with prevention of cellular apoptosis by pathogenic Neisseriae and purified porins -- Analysis of the immune response to Nia meningitidis using a proteomics approach -- Antigen identification starting from the genome: a "reverse vaccinology" approach applied to MenB -- DNA vaccine strategy for effective antibody induction to pathogen-derived antigens.
  • 2005 Springer
    by Constantin Bona ; foreword by Noel R. Rose.
    Structure and function of immune system in vertebrates -- Ontogeny and development of cells mediating innate and adaptive immunity -- Phenotypic characteristics of neonatal B cells -- Molecular characteristics of neonatal B cell repertoire -- Genetically programmed temporal ordered activation of neonatal B cell clones -- Antibody response in fetus and newborn -- Effect of maternal antibodies on neonatal B cell response -- Neonatal autoimmune diseases caused by maternal pathogenic autoantibodies -- Phenotypic characteristics of neonatal T cells -- Expression of MHC molecules in neonates -- Neonatal cytokine network -- Cell-mediated immune responses in neonates -- Fetal and neonatal tolerance -- Development of efficient prophylactic vaccines and theracines for newborns and infants .
  • 2012 Springer
    Mia Levite, editor.
    Dopamine in the Immune System: Dopamine Receptors in Immune Cells, Potent Effects, Endogenous Production and Involvement in Immune and Neuropsychiatric Diseases -- Nerve Driven Immunity: Noradrenaline and Adrenaline -- Acetylcholine and Cholinergic Modulation of Immune Responses -- Glutamate in the Immune System: Glutamate Receptors in Immune Cells, Potent Effects, Endogenous Production and Involvement in Disease -- GABA Is an Effective Immunomodulatory Molecule in the Brain and in the Periphery -- The Effects of Opioids on Immune Cells, Functions and Diseases -- The Effects of Somatostatin on Immune Cells, Functions and Diseases -- Neuropeptide Y: The Story, the Players, the Outcomes -- Vasoactive Intestinal Peptide: Immune Mediator and Potential Therapeutic Agent -- Nerve-Driven Immunity: The Effects of Neurotransmitters on Immune Cells, Functions and Disease -- CGRP -- The Effects of Cannabinoids on Immune Cells, Responses and Diseases.
  • 2010
    Matthew Ryan Clutter.
    Target identification is both a critical and difficult step in the drug discovery process. A novel approach is presented here that utilizes flow cytometry to: 1) identify small molecule signaling network probes, and 2) characterize the diverse network activation states they induce. Signaling events across the network are compared to functional responses to determine the way in which each signaling node influences a given function. Nodes that accurately predict cellular functions that drive disease are promising drug targets. The approach was applied to mast cells to determine which signaling molecules best predicted the degranulation, eicosanoid release, and cytokine secretion induced by stimulation of the cells with IgE and specific antigen crosslinking. Erk and Akt phosphorylation best predicted degranulation; Erk and cJun phosphorylation best predicted eicosanoid release; and Akt phosphorylation alone best predicted cytokine secretion. The results confirmed several known aspects of mast cell IgE-dependent signaling and revealed unknown associations to be tested in future work -- notably, that the cJun pathway plays a role in eicosanoid production and that the Akt pathway is a critical integration point for transcription of most or all cytokine genes. Overall, the results suggest that Erk and Akt are the most promising targets in the IgE signaling network for development of mast cell stabilizing drugs.
  • 2008 Springer
    Klaus Eichmann.
  • 2009 ScienceDirect
    volume editor, Gábor Jancsó.
  • 2016 Springer
    Cris Constantinescu, Razvan Arsenescu, Violeta Arsenescu, editors.
  • 2009 Springer
    edited by Allan Siegel, Steven S. Zalcman.
  • 2007 Springer
    S.R. Pandi-Perumal, Daniel P. Cardinali, Georgios Chrousos.
  • 2009 Springer
    Richard D. Granstein, Thomas A. Luger, editors.
  • 2014 Springer Protocols
    edited by Mark T. Quinn, Frank R. DeLeo.
    The role of neutrophils in the immune system : an overview / Harry L. Malech, Frank R. DeLeo, and Mark T. Quinn -- Isolation of human neutrophils from venous blood / William M. Nausef -- Neutrophil isolation from nonhuman species / Daniel W. Siemsen ... [and 7 others] -- Collection of in vivo transmigrated neutrophils from human skin / Karin Christenson ... [and 6 others] -- Subcellular fractionation of human neutrophils and analysis of subcellular markers / Stine Novrup Clemmensen, Lene Udby, and Niels Borregaard -- Rho family and Rap GTPase activation assays / Richard T. Jennings and Ulla G. Knaus -- Measurement of phospholipid metabolism in intact neutrophils / Susan Sergeant and Linda C. McPhail -- Optical methods for the measurement and manipulation of cytosolic calcium signals in neutrophils / Maurice B. Hallett, Maha Al-Jumaa, and Sharon Dewitt -- Analysis of electrophysiological properties and responses of neutrophils / Deri Morgan and Thomas E. DeCoursey -- Assessment of neutrophil apoptosis / David A. Dorward ... [and 3 others] -- Microinjection methods for neutrophils / Iraj Laffafian ... [and 3 others] -- Generation of functionally mature neutrophils from induced pluripotent stem cells / Colin L. Sweeney ... [and 6 others] -- Neutrophil migration through extracellular matrix / Richard T. Jennings and Ulla G. Knaus -- Spinning disk confocal imaging of neutrophil migration in zebrafish / Pui-Ying Lam ... [and 4 others] -- Detection of bidirectional signaling during integrin activation and neutrophil adhesion / Stuart M. Altman, Neha Dixit, and Scott I. Simon -- Immunofluorescence and confocal microscopy of neutrophils / Lee-Ann H. Allen -- Expressin of genetically encoded fluorescent probes to monitor phospholipid dynamics in live neutrophils / Benjamin E. Steinberg, Marco A.O. Magalhaes, and Sergio Grinstein -- Quantitative assessment of neutrophil phagocytosis using flow cytometry / Pontus Nordenfelt -- Analysis of neutrophil bactericidal activity / Heather A. Parker ... [and 4 others] -- Induction and quantification of neutrophil extracellular traps / Alejandro Sanchez Gonzalez ... [and 3 others] -- Measurement of respiratory burst products, released or retained, during activation of professional phagocytes / Johan Bylund ... [and 4 others] -- Cell-free NADPH oxidase activation assays : "In vitro veritas" / Edgar Pick -- Assessment of priming of the human neutrophil respiratory burst / Margarita Hurtado-Nedelec ... [and 4 others] -- Affinity pruification and reconstitution of human phagocyte flavocytochrome b for detection of conformational dynamics in the membrane / Marcia Riesselman and Algirdas J. Jesaitis -- Evaluation of p47phox phosphorylation in human neutrophils using phospho-specicfic antibodies / Sahra Amel Belambri, Pham My-Chan Dang, and Jamel El-Benna -- Genome-scale transcript analyses with human neutrophils / Scott D. Kobayashi, Daniel E. Sturdevant, and Frank R. DeLeo -- Fast and accurate quantitative analysis of cytokine gene expression in human neutrophils / Nicola Tamassia, Marco A. Cassatella, and Flavia Bazzoni -- High-purity neutrophil isolation from human peripheral blood and saliva for transcriptome analysis / Flavia S. Lakschevitz and Michael Glogauer -- Detection of intact transciption factors in human neutrophils / Patrick P. McDonald and Richard D. Ye -- Disorders of neutrophil function : an overview / Mary C. Dinauer -- Diagnostic assays for chronic granulomatous disease and other neutrophil disorders / Houda Zghal Elloumi and Steven M. Holland -- Diagnostic assays for myeloperoxidase and myeloperoxidase deficiency / William M. Nauseef.
  • 2001 ScienceDirect
    volume editors, Istvan Berczi, Reginald M. Gorczynski.
  • 2013 Springer
    Maziar Divangahi, editor.
    Also available: Print – 2013
  • 2013 Springer
    Ellen Heber-Katz, David L. Stocum, editors.
    Mechanisms of Vessel Regression: Toward an Understanding of the Resolution of Angiogenesis / Mateusz S. Wietecha, Wendy L. Cerny, Luisa A. DiPietro -- Wound Healing in Mammals and Amphibians: Toward Limb Regeneration in Mammals / Aiko Kawasumi, Natsume Sagawa, Shinichi Hayashi -- Cellular Plasticity During Vertebrate Appendage Regeneration / James R. Monaghan, Malcolm Maden -- Cell Signaling Pathways in Vertebrate Lens Regeneration / Jonathan J. Henry, Alvin G. Thomas, Paul W. Hamilton -- Regenerative Medicine: Challenges and Perspectives for Successful Therapies / S. Viswanathan, C. Joshi -- Employing the Biology of Successful Fracture Repair to Heal Critical Size Bone Defects / Jo Ann Cameron, Derek J. Milner, Jung Seok Lee -- Muscle Repair and Regeneration: Stem Cells, Scaffolds, and the Contributions of Skeletal Muscle to Amphibian Limb Regeneration / Derek J. Milner, Jo Ann Cameron -- Neural Regeneration / Melissa M. Steward, Akshayalakshmi Sridhar -- Teleost Fish as a Model System to Study Successful Regeneration of the Central Nervous System / Günther K. H. Zupanc, Ruxandra F. Sîrbulescu -- Epigenetics and Regeneration / Nobuyasu Maki, Hironobu Kimura -- Cell Cycle Regulation and Regeneration / Ellen Heber-Katz, Yong Zhang, Khamila Bedelbaeva.
  • 2012 Karger
    volume editors, Johannes Ring, Ulf Darsow, Heidrun Behrendt.
    Allergy in evolution / Platts-Mills, T.A.E. -- Climate change, environment and allergy / Behrendt, H., Ring, J. -- The hygiene hypothesis does not apply to atopic eczema in childhood / Cramer, C. ... [et al.] -- Molecular genetics of atopic eczema / Ring, J., Mohrenschlager, M., Weidinger, S. -- Mechanisms of immune tolerance to allergens / Fujita, H. ... [et al.] -- TH17 and TH22 in skin allergy / Cavani, A., Pennino, D., Eyerich, K. -- IL-25 induces both inflammation and skin barrier dysfunction in atopic dermatitis / Deleuran, M. ... [et al.] -- Angiogenesis, lymphangiogenesis and atopic dermatitis / Genovese, A. ... [et al.] -- What can dogs bring to atopic dermatitis research? / Olivry, T. -- Can microbial superantigens influence atopic dermatitis flares? / Alomar, A. -- Inflammation-induced alterations in the skin barrier function: implications in atopic dermatitis / Vestergaard, C. ... [et al.] -- Itch and eczema / Darsow, U. -- Eczema herpeticum / Wollenberg, A. -- Bone mineral density in patients with atopic dermatitis / Haeck, I. -- Immunosuppressive effect of prolactin-induced protein / Sugiura, S. ... [et al.] -- Is food allergy testing reliable in pediatric atopic dermatitis? A population-based study / Keck, L.E. ... [et al.] -- New strategies for dealing with staphylococcus aureus colonization and the emerging methicillin-resistant staphylococcus aureus epidemic in atopic dermatitis / Boguniewicz, M. -- Anti-IL-4 as a new strategy in allergy / Schmidt-Weber, C.B. -- New drug targets in atopic dermatitis / Simon, D., Simon, H.U. -- Latest approaches to treating atopic dermatitis / Paller, A.S.

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