Books

all 1625 "A" titles

A

  • Digital
    NCBI Bookshelf2017
  • Print
    editor-in-chief, Charles Mueller ; section editors, Stephen A. McClave [and others] ; managing editor, Jennifer M. Kuhn.
    Status: Not Checked Out
  • Digital
    Database : Clinical Drug Information
  • Digital
    Andrew J. Larner, Alasdair J. Coles, Neil J. Scolding, Roger A Barker.
    Springer2011
    The aim of this new edition is to present information about neurological disorders in a structured and succinct way, following a "trickle down" principle: beginning with overviews and then moving on to specific disease categories. The latter address clinical features (i.e., information accessed by history-taking and physical examination), investigations, differential diagnosis, treatment, and prognosis. Cross-references to the Online Mendelian Inheritance in Man (OMIM) database have been given where relevant. --Preface excerpt.
  • Digital
    edited by Pier Andrea Borea.
    Springer2010
  • Digital
    Margaret C. Slota, DNP, RN, FAAN, editor.
    R2Library2019
    Caring for critically ill children and their families -- Pulmonary system -- Cardiovascular system -- Neurologic system -- Renal system -- Endocrine system -- Gastrointestinal system -- Hematology and immunology systems -- Multisystem issues -- Professional issues: quality, safety, work environment, and wellness.
  • Print
    edited by Judy Trivits Verger, Ruth M. Lebet.
    Status: Not Checked Out
  • Digital
    AACR2017
  • Digital
    HighWire2005-
  • Digital
  • Print
    includes all documents developed under the auspices of the AAMI Sterilization Standards Committee.
    Status: Not Checked Out
    Vol. 1 Contains standards for equipment, decontamination of medica by steam, ethylene oxide, gamma radiation, and electron beam radiation. -- Vol. 2 Contains standards for biomedical equipment. -- Vol. 3 Contains all documents developed under the auspices of the Renal Disease and Detoxification Committee and Hemodialyzer Reuse Submittee.
  • Digital
  • Digital
    Kenneth C. Holmes.
    Cambridge2017
    The atomic structures of macromolecules provide the key to understanding how life works. Aaron Klug led the way in the development of methods for solving such structures and is one of the pioneers of structural molecular biology. He was awarded a Nobel Prize in 1982 for his work. Illuminating both his personal life and scientific achievements, this unique biography begins with Klug's youth in Durban and his studies at Johannesburg, Cape Town and then Trinity College, Cambridge. Holmes proceeds to explore Klug's career from his work on the structure of viruses with Rosalind Franklin at Birkbeck College, London to his time as Director of the MRC Laboratory of Molecular Biology (LMB) in Cambridge and as President of the Royal Society. Drawing on their long-term collaboration, interviews and unique access to Klug's archives, Holmes provides a fascinating account of an innovative man and his place in the history of structural molecular biology.
  • Print
    Richard B. Berry; Claude L. Albertario, Susan M. Harding, Robin M. Lloyd, David T. Plante, Stuart F. Quan, Matthew M. Troester, Bradley V. Vaughn.
    Status: Not Checked Out
    I. User Guide -- II. Parameters to be reported for polysomnography -- III. Technical and digital specificatioins -- IV. Sleep staging rules -- Part 1. Rules for adults -- Part 2. Rules for children -- Part 3. Rules for infants -- V. Arousal rule -- VI. Cardiac rules -- VII. Movement rules -- VIII. Respiratory rules -- Part 1. Rules for adults -- Part 2. Rules for children -- IX. Home sleep apnea testing (HSAT) rules for adults -- Part 1: HAST utilizing repiratory flow and/or effort parameters -- Part 2: HSAT utilizing peripheral arterial tonometry (PAT) -- X. Development process -- XI. Procedural notes -- XII. Glossary ot terms.
  • Digital
    [edited by] Christopher E. Comstock, Christiane K. Kuhl.
    Thieme MedOne Radiology2018
    Introduction to abbreviated breast magnetic resonance imaging / Christopher E. Comstock -- History of MRI in breast cancer screening / Janice S. Sung and Elizabeth A. Morris -- Current clinical evidence on abbreviated breast MRI / Christiane Kuhl -- Technical aspects of abbreviated breast MRI : the original approach / Christiane Kuhl -- Techniques for performing abbreviated breast MRI / R. Edward Hendrick -- Abbreviated breast MR imaging protocols and clinical implementation / Gillian M. Newstead -- Interpretation guidelines / Janice S. Sung and Constance D. Lehman -- MRI-guided biopsy techniques / Carol H. Lee.
  • Print
    Susan Michie, Robert West, Rona Campbell, Jamie Brown, Heather Gainforth.
    Status: Not Checked Out
    This book describes 83 theories of behaviour change, identified by an expert panel of psychologists, sociologists, anthropologists and economists as relevant to designing interventions. For each theory, the book provides a brief summary, a list of its component constructs, a more extended description and a network analysis to show its links with other theories in the book. It considers the role of theory in understanding behaviour change and its application to designing and evaluating interventions.
  • Digital/Print
    edited by Peter Cantillon, Diana Wood.
    Digital : ProQuest Ebook Central2010Limited to 3 simultaneous users
    Print2010
    Applying educational theory in practice / David M. Kaufman -- Course design / John Bligh and Julie Brice -- Collaborative learning / Diana Wood -- Evaluation / Jillian Morrison -- Teaching large groups / Peter Cantillon -- Teaching small groups / David Jaques -- Feedback in medical education : skills for improving learner performance / Joan Sargeant and Karen Mann -- Learning and teaching in the clinical environment / John Spencer -- Written assessment / Lambert W.T. Schuwirth and Cees P.M. van der Vleuten -- Skill-based assessment / Val Wass -- Work-based assessment / John Norcini and Eric Holmboe -- Direct obvservation tools for workplace-based assessment / Peter Cantillon and Diana Wood -- Learning environment / Jill Thistlethwaite -- Creating teaching materials / Jean Ker and Anne Hesketh -- Learning and teaching professionalism / Sylvia R. Cruess and Richard L. Cruess -- Making it all happen : faculty development for busy teachers / Yvonne Steinert -- Supporting students in difficulty / Dason Evans and Jo Brown.
  • Digital
    Savvas Andronikou ... [et al.], (eds.).
    Springer2010
  • Digital
    edited by John D. Schuetz, Toshihisa Ishikawa.
    ScienceDirect2015
    ABC Transporters and Cancer provides invaluable information on the exciting and fast-moving field of cancer research. Here, outstanding and original reviews are presented on a variety of topics. This volume covers ABC transporters and cancer, and is suitable for researchers and students alike.
  • Digital
    Edward B. Noffsinger.
    Springer2013
  • Print
    Jonas Ramnerö, Niklas Törneke.
    Status: Not Checked Out
    Topographical aspects of behavior -- Observing behavior: when, where, and how much? -- Knowing your ABCs -- Learning by association: respondent conditioning -- Learning by consequences: operant conditioning -- Operant conditioning: stimulus control -- Learning by relational framing: language and cognition -- Applying your ABCs -- Functional knowledge -- Dialogue toward change -- Principles and practices -- Principles of treatment: one -- Principles of treatment: two.
  • Digital
    Ayman S. El-Baz, Luca Saba, Jasjit Suri, editors.
    Springer2013
    Covers novel, state-of-the-art strategies in engineering and clinical analysis. Explores approaches for analyzing abdominal imaging, including lung, mediastinum, pleura, liver, kidney and gallbladder. Offers present and future applications as applied to the abdomen and thoracic imaging with the most world-renowned scientists in these fields.
  • Print
    Sahani, Dushyant V.
    Status: Not Checked Out
  • Digital
    Bernd Hamm, Pablo R. Ros, editors.
    Springer2013
    In this book a team of leading experts come together to provide a comprehensive overview of modern imaging of the abdomen and pelvis, with detailed sections on both gastrointestinal and genitourinary imaging. Each chapter has an identical structure and focuses on a particular organ or organ system, allowing the reader to approach the field one topic at a time. Indications for a variety of imaging techniques and examination protocols are clearly described, and the imaging features of normal anatomy and pathologic entities are depicted in an abundance of high-quality images. Care is taken to consider all recent technical developments and new indications, and the diagnostic performance of different imaging modalities is carefully compared. It is anticipated that this book will come to be regarded as the standard work of reference on abdominal and pelvic radiology.
  • Digital
    [edited by] Dushyant V. Sahani, Anthony E. Samir.
    ClinicalKey2017
  • Digital
    Jean-Pierre Després ... [et al.].
    Oxford2006
  • Digital
    edited by Gabriel C. Oniscu, MD, FRCS, John L. Forsythe, MD, FRCS, John Fung, MD, PhD.
    Wiley2013
    Provides transplant professionals with a step-wise approach to abdominal organ retrieval and bench surgery, illustrating complex anatomical situations and providing practice points and decision algorithms. A go-to reference for transplant surgeons, trainees and fellows, as well as for other professionals involved in abdominal organ transplantation.
  • Digital
    edited by lead editor, Richard C. Semelka ; associate editors, Michele A. Brown, Ersan Altun.
    Wiley2016
    Diagnostic approach to protocoling and interpreting MR studies of the abdomen and pelvis -- Liver -- Gallbladder and biliary system -- Pancreas -- Spleen -- Gastrointestinal tract -- Peritoneal cavity -- Adrenal glands -- Kidneys -- Retroperitoneum and body wall -- Bladder and nongender pelvis -- Male pelvis -- Female urethra and vagina -- Uterus and cervix -- Adnexa -- Maternal conditions in pregnancy -- Fetus -- Chest -- Contrast agents -- Magnetic resonance-positron emission tomography (MR-PET).
  • Digital
    Massimo Sartelli, Matteo Bassetti, Ignacio Martin-Loeches, editors.
    Springer2018
    Classification and principals of treatment -- Inflammatory mediators in Intra-abdominal sepsis -- Intra-abdominal sepsis and imaging considerations -- High-risk patients and prognostic factors for abdominal sepsis -- Acute appendicitis: what is the best strategy to treat acute appendicites (both complicated and uncomplicated)? -- Acute cholecystitis -- Acute cholangitis -- Pyogenic liver abscess -- Gastroduodenal perforations -- Small bowel perforations -- Acute colonic diverticulitis -- Postoperative peritonitis: etiology, diagnosis, and treatment -- Damage control surgery in managing abdominal sepsis (Fausto Catena, Italy) -- Ongoing peritonitis -- Evolving treatment strategies for severe Clostridium difficile colitis: defining the therapeutic window -- Complicated intra-dominal infections: principles of antimicrobial therapy -- Antimicrobial armamentarium -- Antimicrobial resistance in intra-abdominal infections -- The role of Candida in abdominal sepsis -- The value and interpretation of microbial specimens in the management of cIAI -- Appropriate antimicrobial therapy in critically ill patients -- Hemodynamic support -- Adjunctive therapies in abdominal sepsis -- Impact and management of abdominal compartment syndrome in patients with abdominal sepsis -- Thromboprophylaxis in patiens with abdominal sepsis -- Nutritional support for abdominal sepsis.
  • Digital
    Antonio Daniele Pinna, Giorgio Ercolani, editors.
    Springer2015
    1. Immunosuppression in solid organ transplantation -- 2. Infection Complications after Abdominal Organ Transplantation -- 3. National Transplant Network. Donor selection and evaluation criteria -- 4. The safety of donor -- 5. Medical disease after abdominal solid organ transplantation and the risk of solid and hematologic malignant tumor after transplantation) -- 6 Indication and timing -- 7. The donor procurement -- 8. Orthotopic liver transplantation -- 9. Anesthetic and perioperative management for liver transplantation -- 10 Living donor liver transplantation -- 11. Hepatic Acute and chronic rejection -- 12. Postoperative technical complications -- 13. Percutaneous management of biliary and vascular complications -- 14. Re-transplantation (Causes, Outcome) -- 15. Indication and timing -- 16. The donor procurement: Standard technique for procurement in cadaveric donors -- 17. Live donor evaluation -- 18. Living donor nephrectomy -- 19. Renal Transplantation: Surgical technique -- 20. The intraoperative and perioperative management of Kidney transplantation -- 21. Kidney acute and chronic rejection -- 22. Kidney Transplantation: Post-Operative Technical Complications -- 23. Indications and timing -- 24. The donor procurement -- 25 Transplantation -- 26 Abdominal wall transplantation and technique -- 27. Anesthetic and perioperative management for Intestinal transplantation -- 28. Segmental Living-related Small Bowel Transplantation -- 29. Intestinal Acute and Chronic rejection -- 30. Combined Kidney-Liver Transplantation -- 31. Kidney-pancreas Transplantation.
  • Digital
    Berthold Block.
    Thieme MedOne Radiology2017
    General -- Basic physical and technical principles -- Blood vessels : the aorta and its branches, the vena cava and its tributaries -- Liver -- Porta hepatis -- Gallbladder -- Pancreas -- Stomach, duodenum, and diaphragm -- Spleen -- Kidneys -- Adrenal glands -- Bladder, prostate, and uterus -- Quick guide -- The sono consultant -- Documentation.
  • Digital
    Ellen J. Hagopian, Junji Machi, editors.
    Springer2014
    Abdominal Ultrasound for Surgeons provides a comprehensive guide to the use of ultrasonography in surgical practice of abdominal diseases. The content is divided into three major sections focusing on basic principles of ultrasound, ultrasound anatomy and pathology of the abdomen, and employment of ultrasound of the abdomen in surgical practice. A final section is dedicated to the logistics of incorporating ultrasound into a surgical practice. The first section provides an introduction to the principles of ultrasonography focusing on ultrasound physics, equipment, and instrumentation. A detailed approach to the various scanning methods and image interpretation is demonstrated with illustrations, images, and video. The second section focuses on ultrasound anatomy of the abdomen. Each chapter demonstrates the normal and abnormal ultrasound anatomy of specific abdominal organ or organ systems (abdominal wall, liver, pancreas, biliary, stomach, anorectum, retroperitoneum, vascular) with illustrations and images. The current status and technique of endoscopic ultrasound of the upper and lower gastrointestinal tracks is addressed in this section. The third section provides a state-of-the-art review of the status of each major application of abdominal ultrasound in surgery. Topics range from trauma ultrasound and laparoscopic staging to techniques in ultrasound guidance and three-dimensional targeting. This section provides a comprehensive review of the employment of interventional, intraoperative, laparoscopic, transabdominal and endoscopic ultrasound. The fourth and last section addresses the practice aspects of incorporation of ultrasound into a surgical practice. Abdominal Ultrasound for Surgeons will serve as a very useful resource and guide for surgeons and students with little to some experience in ultrasound, including practicing surgeons, surgical fellows, and surgical residents.
  • Digital
    Dalila Patrizia Greco, Elio Borgonovi, editors.
    Springer2019
    This book presents different patient-oriented perspectives from surgeons, economic evaluation and management researchers, and business companies active in the healthcare sector, striking a balance between the appropriateness/effectiveness of treatment and efficiency/cost. It does not include technical surgical details, but instead provides the necessary knowledge regarding different groups of patients to help economic and management researchers make accurate evaluations. Although partially based on the specific case of abdominal wall surgery in the Italian health system, the book defines a model that can, with the necessary adaptations, be applied in other national contexts. It also analyzes different reimbursement systems and methods of data collection. This approach supports the evolution form evidence-based medicine (EBM) to the future of real-world data (big data analysis). Further, it highlights the critical issue of "silos" reimbursement, which is the pillar of DRG, and proposes methodology to evaluate the direct and indirect benefit and costs of surgery (for example quality of care, costs incurred in cases of surgical complications due to the use of inappropriate, low-cost material or due to surgical procedure. It is a valuable resource for clinicians, surgeons, policymakers and managers in the field.
  • Digital
    [edited by] John E. Niederhuber, James O. Armitage, James H. Doroshow, Michael B. Kastan, Joel E. Tepper.
    ClinicalKey2020
    "Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up"--Publisher's description.
  • Digital
    [edited by] Alden H. Harken, Ernest E. Moore.
    ClinicalKey2018
    I. General topics -- Are you ready for your surgical rotation? -- Cardiopulmonary resuscitation -- How to treat all cardiac dysrhythmias -- How to think about shock -- Congestive heart failure (CHF) and pulmonary insufficiency -- Mechanical ventilation -- Why get arterial blood gases? -- Fluids, electrolytes, Gatorade, and sweat -- Nutritional assessment, parenteral, and enteral nutrition -- What does postoperative fever mean? -- Surgical wound infection -- Priorities in evaluation of the acute abdomen -- Surgical infectious disease -- Risks of blood-borne disease -- Sepsis -- Frailty -- II. Trauma. Initial assessment -- Posttraumatic hemorrhagic shock -- Traumatic brain injury -- Spinal cord injuries -- Penetrating neck trauma -- Blunt thoracic trauma -- Penetrating thoracic trauma -- Blunt abdominal trauma -- Penetrating abdominal trauma -- Hepatic and biliary trauma -- Splenic trauma -- Pancreatic and duodenal injury -- Trauma to the colon and rectum -- Pelvic fractures -- Upper urinary tract injuries -- Lower urinary tract injury and pelvic trauma -- Extremity vascular injuries -- Facial lacerations -- Maxillofacial trauma -- Basic care of hand injuries -- Burns -- Pediatric trauma -- III. Abdominal surgery. Appendicitis -- Gallbladder disease -- Pancreatic cancer -- Acute pancreatitis -- Diagnosis and therapy of chronic pancreatitis -- Portal hypertension and esophageal varices -- Gastroesophageal reflux disease -- Esophageal cancer -- Acid-peptic ulcer disease -- Small bowel obstruction -- Intestinal ischemia -- Diverticular disease of the colon -- Acute large bowel obstruction -- Inflammatory bowel disease -- Upper gastrointestinal bleeding -- Lower gastrointestinal bleeding -- Colorectal polyps -- Colorectal carcinoma -- Anorectal disease -- Inguinal hernia -- Bariatric surgery -- IV. Endocrine surgery. Hyperparathyroidism -- Hyperthyroidism -- Thyroid nodules and cancer -- Surgical hypertension -- Adrenal laparoscopic adrenalectomy incidentaloma -- V. Breast surgery. Breast masses -- Primary therapy for breast cancer -- VI. Other cancers. What is cancer? -- Melanoma -- Non-melanoma skin cancer -- Parotid tumors -- Neck masses -- VII. Vascular surgery. What is atherosclerosis? -- Arterial insufficiency -- Carotid disease -- Abdominal aortic aneurysm -- Venous disease -- Noninvasive vascular diagnostic laboratory -- VIII. Cardiothoracic surgery. Coronary artery disease -- Mitral stenosis -- Mitral regurgitation -- Aortic valvular disease -- Thoracic surgery for non-neoplastic disease -- Lung cancer -- Solitary pulmonary nodule -- Dissecting aortic aneurysm -- IX. Pediatric surgery. Hypertrophic pyloric stenosis -- Intestinal obstruction of neonates and infants -- Tracheoesophageal malformations -- Tracheoesophageal malformations -- Congenital diaphragmatic hernia -- Abdominal tumors -- Congenital cysts and sinuses of the neck -- X. Transplantation. Liver transplantation -- Kidney and pancreas transplantation -- Heart transplantation -- Mechanical circulatory support -- Lung transplantation -- Penile and scrotal urologic emergencies -- Urolithiasis -- XI. Urology. Renal cell carcinoma -- Bladder cancer -- Prostate cancer -- Urodynamics and voiding dysfunction -- Pediatric urology -- XII. Health care. Can health care be reformed? -- Ethics in the surgical intensive care unit -- Professionalism -- Required reading.
  • Digital
    Yi Wang, editor.
    Springer2019
    This book introduces the clinical application of ABO-incompatible transplantation. In the first part, it starts with the history, blood group antigen, antibody associated with ABO blood type, pathophysiology and pathology and related knowledge. In the second part, it covers clinical experience sharing of ABO-incompatible of heart, liver, lung and kidney transplantation. It provides a systematic methodologies and protocols. .
  • Digital
    Bernard Hébert.
    Springer2010
  • Digital
    Antoine Lemaire.
    Springer2009
  • Digital
    Vincent Pointillart ; avec la collaboration de Christian Soderlund.
    Springer2009
  • Digital
    Patrick Ritz, Jérôme Dargent.
    Springer2009
  • Digital
    Jean-Claude Turpin.
    Springer2010
  • Digital
    edited by Sam Rowlands, Dorset HealthCare and the School of Health and Social Care, Bournemouth University, Bournemouth, UK.
    Cambridge2014
    1. An historical perspective -- 2. Ethics -- 3. Epidemiology -- 4. Psychosocial factors in women requesting abortion -- 5. Support and counseling -- 6. Ultrasound scanning in early pregnancy -- 7. Early medical abortion -- 8. Vacuum aspiration -- 9. Medical abortion after nine weeks -- 10. Dilatation and evacuation -- 11. Pain control -- 12. Follow-up -- 13. Contraception after abortion -- 14. Complications and safety -- 15. Women with medical problems -- 16. Feticide -- 17. Fetal anomaly -- 18. Longer-term outcomes in women requesting abortion -- 19. Myths and misinformation -- 20. Stigma and issues of conscience -- 21. More than one abortion -- 22. Factors associated with second trimester abortion -- 23. Staff perspectives -- 24. Mid-level providers -- 25. Telemedicine -- 26. Decriminalizing abortion, the Australian experience -- 27. Abortion in international human rights law.
  • Digital
    Peter H. Abrahams, Jonathan D. Spratt, Marios Loukas, Albert-Neels van Schoor.
    ClinicalKey2019
    "Abrahams' and McMinn's Clinical Atlas of Human Anatomy, 8th Edition delivers the straightforward visual guidance you need to perform confidently in all examinations and understand spatial relationships required during your medical training, while also acquiring the practical anatomical knowledge needed for your future clinical career. Respected authority Prof. Peter Abrahams and his team of leading international anatomists and radiologists link a vast collection of clinical images to help you master all the essential correlations between the basic science of anatomy and its clinical practice"--Publisher's description.
  • Digital/Print
    editors, Jean-Franc̜ois H. Geschwind, Michael D. Dake.
    Digital : eBook Comp Acad2014
    Print2014
    "The 'Interventional Radiology' volume of the landmark reference "Abrams' Angiography" has now been expanded and thoroughly revised to reflect dynamic advances in interventional radiology. More than 60 contributors representing a "Who's Who" of the specialty provide comprehensive, step-by-step coverage of all contemporary vascular and nonvascular interventional procedures. Major sections discuss today's equipment and describe interventions for specific disorders of each organ system, as well as for trauma, pediatric diseases, abscess drainage, and miscellaneous disorders. More than 1,100 illustrations complement the text. This edition incorporates an extensive new section on interventional oncologic procedures. The section covers all organ-specific cancers for which interventional therapies are used. Other sections include artervenous malformations, liver diseases, arterial occlusive disease, aneurysms, traumatic arterial injuries, hemorrhage, and venous diseases. It also has full color and an accompanying online site to access the content anytime"--Provided by publisher.
  • Digital
    editors, Dale A. Dangleben, James Lee, Firas Madbak.
    AccessSurgery2013
    A high-yield review for the American Board of Surgery In-Training Exam, this text is a comprehensive review for the American Board of Surgery in-Training Exam. It delivers everything needed to excel on the exam: test-taking tips, high-yield facts, more than 300 multiple-choice questions, clinical pearls, illustrations of key anatomy, and bullet point text. Features: focused exclusively on the ABSITE exam, rather than being a combined ABSITE and board review book; organized by organ system; and valuable as last-minute review or a general framework for preparing for the exam.
  • Digital
    Doris Kung, Thy Nguyen, Ritu Das.
    Springer2019
    This concise review book provides a set of evidence-based and up-to-date study questions that demonstrate knowledge of common neurological diseases. Presented in a case-based format, each chapter includes several questions that are intended for medical students, residents rotating through neurology, and neurologists looking for study sources. Filling a need for a supplemental resource to use when studying for board exams, particularly the NBME and RITE, Absolute Case-Based Neurology serves as an invaluable guide to neurology rotations, tests and daily practice.
  • Digital
    Daniel M. Trifiletti, Nicholas G. Zaorsky, editors.
    Springer2019
  • Digital
    Hugh Morris Gloster, Jr., Lauren E. Gebauer, Rachel L. Mistur.
    Springer2015
  • Digital
    Mona Sazgar, Michael G. Young.
    Springer2019
    This book contains the most essential information needed for an epilepsy/ EEG rotation. Chapters are formatted with bullet points and feature clinical pearls. Concise and easy-to-read, this quick reference provides neurology residents, clinical neurophysiology and epilepsy fellows, and other clinicians with the most critical information in epilepsy and EEG in a simplified, yet comprehensive format. Divided into two sections, the book first covers the diagnosis, characteristics, and treatment of epilepsy. The second section focuses on EEG placement, procedures, and patterns in various neurological disorders.
  • Digital
    Kevin Conrad, editor.
    Springer2016
    This concise guide covers the evolution and expanding scope of hospital medicine and the variety of clinical, ethical and administrative situations a Hospitalist encounters. 500 questions on inpatient care, co-management of patients and hospital system management are provided with the goal of assessing clinical and academic competency. Questions feature actual cases with evidence-based solutions. Useful to physicians, house staff and advanced nurse practitioners, this up-to-date referenced learning text encompasses all aspects of hospital care.
  • Digital
    Alluru S. Reddi.
    Springer2016
    Written in a succinct question and answer format, this comprehensive resource covers all areas of nephrology and common clinical scenarios. Nearly 1000 questions with detailed answers provide nephrology fellows, practicing nephrologists and clinicians a better understanding of nephrology and aid preparations for nephrology and internal medicine boards. Absolute Nephrology Review features the latest evidence and guidelines while fulfilling a critical need within the nephrology community.
  • Digital
    Zachary David Levy, editor.
    Springer2017
    This practical question and answer book covers topics within the field of neurocritical care, including aspects of neurology, neurosurgery, general critical care, and emergency medicine. Each chapter serves as a standalone test, comprised of approximately 100 questions, and closely mimics the tone and scope of the United Council for Neurologic Subspecialties (UCNS) certification exam in neurocritical care. Rationale and discussion are provided in the answers section at the end of each exam. This practical study guide will help prepare critical care fellows and residents from a variety of backgrounds (including internal medicine, neurology, anesthesiology, and emergency medicine) for the UCNS exam.
  • Digital
    by Yasser M. Awaad.
    Springer2018
    This practical book features more than 1000 questions and answers with illustrations for pediatric neurologists, adult neurologists, general pediatricians and students taking their initial board examination and maintenance of certification. All questions are in multiple choice format and followed by the correct answer with a full explanation and appropriate references. Chapters are sectioned by different topics in pediatric neurology, including Epilepsy, Metabolic Disorders and Movement Disorders and other topics. Timely and thorough, this is a handy and succinct resource.
  • Digital
    Alex Avdeef.
    Wiley2012
    Introduction Transport model pKa determination -- Octanol-water partitioning -- Liposome-water partitioning -- Solubility -- Permeability -- Pampa -- Permeability Caco 2/MDCK -- Permeability blood brain barrier.
  • Print
    Status: Not Checked Out
    1. [Symposia I-III] -- 2. [Symposia IV-VII] -- 3. Colloquia I-XIV -- 4. General sessions A-F -- 5. General sessions G-J -- [6] Author index -- [7] Supplement I-
  • Print
  • Print
  • Digital
    arranged by Terri Grodzicker, David Stewart, Bruce Stillman.
    Cold Spring Harb Lab Press2008
  • Print
  • Print
    Conrad Berens and L. Benjamin Sheppard.
    Status: Not Checked Out
  • Digital
    Association of Medical Colleges.
    R2Library2016
    "The seventh biennial Harrison Survey, jointly sponsored by the Association of American Medical Colleges (AAMC) and the Society for Academic Continuing Medical Education (SACME), documents an academic enterprise that displays three major characteristics, somewhat in opposition to its traditional image as an isolated, passive educational entity. First, continuing medical education/ continuing professional development (CME/CPD) is increasingly integrated into the functions and missions of academic medical centers, academic health systems, and medical schools of the United States and Canada. Second, it demonstrates numerous examples of innovation and scholarship in educational design and operation. Finally, possibly as a result of the first two elements, there is an increased focus on assessing the impact of CME/CPD activities on learner competence, performance, and health care outcomes. The purpose of the survey is to help identify and understand the placement and alignment of the CME/CPD unit within the academic medical center (AMC). Survey findings will benefit those in the CME/CPD field who can use the data to assess and enhance the shape and scope of CME/CPD and who will share the information with AMC leaders, including deans, CEOs, and others. The survey generates broad but important findings for discussion and analysis in three areas: CME/CPD's structure, its function relative to relationships and educational methods, and its scope, reach, and impact. Throughout this report, data from the last Harrison Survey in 2013 are used for comparative purposes"--Executive summary.
  • Print
    Kenney, Matthew G.
    Status: Not Checked Out
  • Digital
    Mamta Swaroop, Sanjay Krishnaswami, editors.
    Springer2016
    Part 1. General Considerations -- 1. Global Burden of Surgical Disease and the Role of Academia -- 2. Promoting, Developing, and Sustaining Academic Global Surgery Programs.-3. Ethics in Global Surgery -- Part 2. Career -- 4. Preparing and Sustaining Your Career in Academic Global Surgery -- 5. Balancing Global Surgery with Traditional Career and Life Demands -- Part 3. Clinical -- 6. Guidelines and Parameters for Ideal Short-Term Interactions: Disaster Relief -- 7. How to Set Up for an Ideal Long Term Clinical Interaction -- Part 4. Research -- 8. Current Research Needs and Priorities -- 9. Research Methods Appropriate and Applicable to Global Surgery -- 10. Funding for Global Surgical Programs -- Part 5. Education -- 11. Developing Educational Opportunities for Trainees on Both Sides -- 12. The Role of Educational Research in the Global Setting -- Part 6. Resources -- 13. Tools Useful for the Academic Global Surgeon.
  • Digital
    Julia Miller Vick, Jennifer S. Furlong, Rosanne Lurie.
    ProQuest Ebook Central2016
    Part I. What You Should Know Before You Start -- 1. The Structure of Academic Careers -- 2. Hiring from the Institution's Point of View -- Part II. Planning and Timing Your Search -- 3. Becoming a Job Candidate: The Timetable for Your Search -- 4. Deciding Where and When to Apply -- 5. Building an Academic Network -- 6. Letters of Recommendation -- 7. Learning About Openings -- Part III. Written Materials for the Job Search: Suggestions and Samples -- 8. Responding to Position Announcements -- 9. CVs -- 10. Additional Application Materials -- 11. Online Presence -- 12. Job Hunting Correspondence -- IV. Conducting the Search -- 13. Interviewing -- 14. Preliminary Interviews -- 15. The Campus Visit -- 16. Job Offers, Negotiations, Acceptances, and Rejections -- Part V. After You Take the Job -- 17. Starting the Job -- 18. Knowing About and Getting Tenure -- 19. Changing Jobs -- Part VI. Additional Considerations -- 20. Dual-Career Couples and Pregnant on the Job Market -- 21. International Job Search -- 22. Cultural and Experiential Diversity -- Part VII. Beyond Faculty Careers -- 23. Exploring the Expanded Job Market -- Appendices -- Appendix 1: National Job Listing Sources and Scholarly and Professional Associations -- Appendix 2: Additional Resources -- Appendix 3: Sample Application Package -- Index -- Comments.
  • Digital
    Laura Weiss Roberts, editor.
    Springer2013
    Attaining professional success and finding personal happiness in academic medicine is not an easy path, yet both are critical if the future is to be brighter through better science, better clinical care, better training, better responsiveness to communities, and better stewardship and leadership in the health professions. This concise, easy to read title consists of "mini" chapters intended as a resource to assist early- and middle-career physicians, clinicians, and scientists in understanding the unique mission of academic medicine and building creative, effective, and inspiring careers in a challenging field.
  • Digital
    Peter Seldin, J. Elizabeth Miller.
    ProQuest Ebook Central2009Limited to 1 simultaneous users
  • Digital
    Anne Walling.
    Springer2018
  • Digital
    Linda Deer Richardson ; Benjamin Goldberg, editor.
    Springer2018
    This volume deals with philosophically grounded theories of animal generation as found in two different traditions: one, deriving primarily from Aristotelian natural philosophy and specifically from his Generation of Animals; and another, deriving from two related medical traditions, the Hippocratic and the Galenic. The book contains a classification and critique of works that touch on the history of embryology and animal generation written before 1980. It also contains translations of key sections of the works on which it is focused. It looks at two different scholarly communities: the physicians (medici) and philosophers (philosophi), that share a set of textual resources and philosophical lineages, as well as a shared problem (explaining animal generation), but that nevertheless have different concerns and commitments. The book demonstrates how those working in these two traditions not only shared a common philosophical background in the arts curricula of the universities, but were in constant intercourse with each other.0This book presents a test case of how scholarly communities differentiate themselves from each other through methods of argument, empirical investigation, and textual interpretations. It is all the more interesting because the two communities under investigation have so much in common and yet, in the end, are distinct in a number of important ways.
  • Digital
    Xuguang Sun.
    Springer2018
  • Digital
    David E. Wazer, Douglas W. Arthur, Frank A. Vicini, editors.
    Springer2009
  • Digital
    edited by Fenghe Qiu, Garry Scrivens.
    ScienceDirect2018
    1. Accelerated predictive stability: an introduction -- 2. Regulatory expectations and industry practice on stability testing -- 3. Theory and fundamentals of accelerated predictive stability (APS) studies -- 4. Practical considerations -- 5. The humidity exposure of packaged products -- 6. Data evaluation and statistical methods -- 7. Strategies for improving the reliability of accelerated predictive stability (APS) studies -- 8. Integration of APS into a rapid, early clinical drug product development paradigm -- 9. Accelerated predictive stability (APS) regulatory strategies -- 10. Embedding APS within business -- 11. Implementing an accelerated predictive stability program -- 12. Accelerated stability assessment program (ASAP) applications in a postapproval environment -- 13. ASAP application: unstable drug candidate in early development -- 14. ASAP application in suspension, liquid, lyophilized, and controlled-release drug products -- 15. Applications of ASAP to generic drugs -- 16. ASAP application: nicotine lozenges -- 17. ASAP applications in clinical development: prediction of degradation and dissolution performance -- 18. Accelerated predictive stability (APS) applications: packaging strategies for controlling dissolution performance -- 19. Accelerated stability modeling: investigation of disintegration time of a drug product with sodium bicarbonate -- 20. Accelerated stability modeling: an ionic liquid drug product -- 21. Accelerated stability modeling: assay loss of nicotine lozenges -- 22. Accelerated stability modeling: desolvation of a solvate drug product.
  • Digital
    Jung W. Suh, Youngmin Kim.
    ScienceDirect2014
    "Beyond simulation and algorithm development, many developers increasingly use MATLAB even for product deployment in computationally heavy fields. This often demands that MATLAB codes run faster by leveraging the distributed parallelism of Graphics Processing Units (GPUs). While MATLAB successfully provides high-level functions as a simulation tool for rapid prototyping, the underlying details and knowledge needed for utilizing GPUs make MATLAB users hesitate to step into it. Accelerating MATLAB with GPUs offers a primer on bridging this gap. Starting with the basics, setting up MATLAB for CUDA (in Windows, Linux and Mac OS X) and profiling, it then guides users through advanced topics such as CUDA libraries. The authors share their experience developing algorithms using MATLAB, C++ and GPUs for huge datasets, modifying MATLAB codes to better utilize the computational power of GPUs, and integrating them into commercial software products. Throughout the book, they demonstrate many example codes that can be used as templates of C-MEX and CUDA codes for readers' projects. Download example codes from the publisher's website: http://booksite.elsevier.com/9780124080805/ Shows how to accelerate MATLAB codes through the GPU for parallel processing, with minimal hardware knowledge -- Explains the related background on hardware, architecture and programming for ease of use -- Provides simple worked examples of MATLAB and CUDA C codes as well as templates that can be reused in real-world projects."--Provided by publisher.
  • Digital
    Sigmund Simonsen.
    Springer2012
    This book is the first major work that addresses a core question in biomedical research: the question of acceptable risk. The acceptable level of risks is regulated by the requirement of proportionality in biomedical research law, which state that the risk and burden to the participant must be in proportion to potential benefits to the participant, society or science. This investigation addresses research on healthy volunteers, children, vulnerable subjects, and includes placebo controlled clinical trials.
  • Digital
    edited by Louise C. Johns, Eric M.J. Morris, and Joseph E. Oliver.
    Wiley2013
    Introduction to mindfulness and acceptance-based therapies for psychosis / Joseph E. Oliver, Candice Joseph, Majella Byrne, Louise C. Johns and Eric M.J. Morris -- Theory on voices / Fran Shawyer, Neil Thomas, Eric M.J. Morris and John Farhall -- Emotional processing and metacognitive awareness / Claire Hepworth, Helen Startup and Daniel Freeman -- Clinical assessment and assessment measures / John Farhall, Fran Shawyer, Neil Thomas and Eric M.J. Morris -- Acceptance and commitment therapy case formulation / Patty Bach -- Engaging people with psychosis in acceptance and commitment therapy and mindfulness / Brandon A. Gaudiano and Andrew M. Busch -- Acceptance and commitment therapy for voices / Neil Thomas, Eric M.J. Morris, Fran Shawyer and John Farhall -- Acceptance and commitment therapy for delusions / José Manuel García Montes, Marino Pérez Álvarez and Salvador Perona Garcelán -- Acceptance and commitment therapy for emotional dysfunction following psychosis / Ross White -- Person-based cognitive therapy for distressing psychosis / Lyn Ellett -- Spirituality: a new way into understanding psychosis / Isabel Clarke -- The service user experience of acceptance and commitment therapy and person-based cognitive therapy / Joseph E. Oliver, Mark Hayward, Helena B. McGuiness -- Acceptance and commitment therapy for first-episode psychosis / Joseph E. Oliver and Eric M.J. Morris -- Acceptance and commitment therapy for psychosis in acute psychiatric admission settings / Gordon Mitchell and Amy McArthur -- Developing acceptance and commitment therapy for psychosis as a group-based intervention / Amy McArthur, Gordon Mitchell and Louise C. Johns -- Group person-based cognitive therapy for distressing psychosis / Clara Strauss and Mark Hayward -- Appendix A: chessboard metaphor -- Appendix B: leaves-on-the-stream metaphor -- Appendix C: passengers-on-the-bus metaphor -- Appendix D: person-in-the-hole metaphor -- Appendix E: polygraph metaphor -- Appendix F: see the wood for the trees (and other helpful advice for living life) -- Appendix G: skiing metaphor -- Appendix H: tug-of-war-with-the-monster metaphor.
  • Digital
    Lauren Mizock and Zlatka Russinova.
    Oxford Clinical Psychology2016
    The history of the treatment of mental illness -- Acceptance and the recovery paradigm in mental health care -- The multiple dimensions of the acceptance of mental illness -- Barriers and facilitators to acceptance of mental illness -- The process of acceptance of mental illness -- Acceptance of mental illness among women : intersectional stigma -- Acceptance of mental illness among men : exploring masculinities and mental health -- Racial-ethnic cultural factors in the process of acceptance of mental illness -- LGBT factors in the process of acceptance of mental illness -- Clinical applications and investigation of the acceptance of mental illness.
  • Digital
    edited by Dawn Camp-Sorrell, RN, MSN, FNP, AOCN, Laurl Matey, MSN, RN, CHPN.
    R2Library2017
    "The use of venous access devices (VADs) is central to the care that nurses provide to patients with cancer. Oncology nurses must base their practice on evidence-based research when available, but a lack of evidence has been a professional challenge for decades. With limited research to guide practice, ongoing controversies remain regarding optimal device management. Since 1989, the Oncology Nursing Society (ONS) has provided guidelines to establish a foundation for access device management. With this new text, ONS has identified practice standards, developed from a synthesis of evidence, critical review, and analysis of aspects of access device management for which nursing is accountable. Access Device Standards of Practice for Oncology Nursing reviews the controversies in access device care, explores the range of devices currently available, details the advantages and disadvantages of each device to ensure optimal selection based on patient needs, and discusses the key legal ramifications concerning access devices and their management. With access device technology becoming more complex, this text is an essential resource for nurses practicing in a wide range of settings to ensure safe, effective care of patients with VADs."--Publisher's description.
  • Digital/Print
    Digital : WHO2014
    Print2014
  • Digital
    edited by Aldo Rosano.
    Springer2018
    This salient volume surveys the state of access to primary care and preventive health services by migrants, refugees, and asylum seekers across Europe. Experts in public health and allied fields identify obstacles to healthcare interventions for migrants, including costs, legal status, health-related behaviors and beliefs, and cultural and language barriers. The book includes the latest data concerning access to specific preventive services (e.g., vaccinations, colorectal screenings), specific issues of women and sexual minorities, and the potential for health promotion in prevention. Best practices for improving access are outlined as a basis for public health and policy directives toward reducing health disparities between migrant and native populations. Among the topics covered: Access to medical examination for prevention among migrants Access and barriers to infant vaccinations, female cancer screening and colorectal screening among migrant populations Provision and policy gap between the primary and preventive care required by and the care provided to LGBTQ+ migrants, refugees, and asylum seekers. Health related lifestyles and intermediate health conditions of migrants. Quality of primary healthcare and preventive health services provided to migrants Adaptations of primary health care for migrants Access to primary health care and policies on migration and health at a time of economic crisis Dedicated to bridging research and policy gaps in this vital area, Primary Care Access and Preventive Health Services of Migrants is intended for an international audience of academics, researchers, policymakers, and practitioners in public health and related disciplines. -- Publisher description.
  • Digital
    Database : McGraw-Hill MedicalUsers must register and log in to access some features. To maintain their personal accounts users must log in to AEM via the Stanford network every 90 days
    AccessEmergency Medicine is a complete online service that allows users to quickly search the diagnosis and treatment of a broad range of emergency cases with videos.
  • Digital
    Website : AccessEmergency MedicineUsers must register and sign in to take a test. To maintain their personal accounts users must log in to AEM via the Stanford network every 90 days
    Interactive self-assessment section of AccessEmergency Medicine website. Allows users to create and take custom tests based on standard review texts.
  • Digital
    Database : McGraw-Hill MedicalUsers must register and log in to access some features. To maintain their personal accounts users must log in to AM via the Stanford network every 90 days
    A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.
  • Digital
    Toy, Eugene C.
    AccessMedicine2006-
    Clinical cases selected from the LANGE Case Files series, edited by Eugene C. Toy, MD.
  • Digital
    Database : McGraw-Hill Medical
    "AccessPediatrics from McGraw-Hill Medical covers the entire span of pediatric practice, from neonatology through adolescent medicine. Updated regularly and optimized for viewing on any device, this comprehensive online pediatric resource provides instant access to information essential for completing evaluation, diagnosis, and case management decisions, as well as for pursuing research or self-assessment and board review -- all in one place."--Website.
  • Digital
  • Digital
    Website : AccessSurgeryUsers must register and sign in to take a test
    Interactive self-assessment section of AccessSurgery website. Allows users to create and take custom tests based on standard review texts.
  • Digital
    Nigel Raby, Laurence Berman, Simon Morley, Gerald de Lacey.
    ClinicalKey2015
    Since it was first published, Accident and Emergency Radiology: A Survival Guide has become the classic in-my-pocket-reference and an indispensable aid to all those who work in the Emergency Department. The core and substantial value lies in the step-by-step analytical approaches which help you to answer this question: "These images look normal to me, but . . . how can I be sure that I am not missing a subtle but important abnormality?" Ensure accuracy in reading and interpretation of any given image. Common sources of error and diagnostic difficulty are highlighted. Prevent mistakes. Pitfalls and associated abnormalities are emphasized throughout. Avoid misdiagnoses. Normal anatomy is outlined alongside schemes for detecting variants of the norm. Each chapter concludes with a summary of key points. Will provide a useful overview of the most important features in diagnosis and interpretation.Easily grasp difficult anatomical concepts. Radiographs accompanied by clear, explanatory line-drawings.
  • Print
    Ho, Benny.
    Status: Not Checked Out
  • Digital
    Narayan Yoganandan, Alan M. Nahum, John W. Melvin, The Medical College of Wisconsin Inc on behalf of Narayan Yoganandan, editors.
    Springer2015
    This book provides a state-of-the-art look at the applied biomechanics of accidental injury and prevention. The editors, Drs. Narayan Yoganandan, Alan M. Nahum and John W. Melvin are recognized international leaders and researchers in injury biomechanics, prevention and trauma medicine. They have assembled renowned researchers as authors for 29 chapters to cover individual aspects of human injury assessment and prevention. This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention. The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases, and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers, and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.
  • Digital
    Jesse M. Rodriguez.
    The predisposition to many diseases is strongly influenced by the genome of an individual. However, the association between the genome and most diseases is not fully understood, so there is an ongoing effort to characterize these associations. One way to characterize disease-genome associations is by studying the familial and ancestral origin of individuals in the context of disease. This kind of study relies on the fact that individuals with shared origins tend to have genomes and phenotypes that are similar to one another. Detailed information regarding familial and ancestral origin is often unknown, however, it can be inferred computationally by examining the genome. Therefore, it is important that we have accurate methods to infer this information in order to facilitate disease-genome associations. In this dissertation, I describe the contributions I have made to accurately inferring the ancestry and relatedness of individuals based on their genomes. First, I describe my work on ALLOY, a method to infer the ancestral origin of segments of the genome based on a factorial HMM. Next, I present PARENTE, a method to infer which individuals in a group are related to one another by detecting genomic segments that are identical-by-descent (IBD) using an embedded likelihood ratio test. Finally, I present PARENTE2, an extension of PARENTE that incorporates linkage disequilibrium information and results in significantly higher accuracy.
  • Print
    [principal investigator, Shirley Otis-Green].
    Status: Not Checked Out
    "The primary aim of this innovative psycho-oncology educational initiative is to improve the delivery of palliative care by psychologists, social workers and spiritual care professionals through an intensive advocacy and leadership training program"--Website.
  • Digital
    ProQuest Ebook Central2008Limited to 1 simultaneous users
    Case Interviewsat a Glance -- Case Interview Primer -- The WetFeet Way -- Case Interview Prep -- The Recruiter's Perspective -- Case Examples -- Additional Resources.
  • Digital
    Pasquale Perrone Filardi, editor.
    Springer2015
    This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on reducing morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. ACEi and ARBS in Hypertension and Heart Failure is a highly practical reference reviewing the evidence and providing a rationale for the appropriate use of RAS antagonists in cardiovascular diseases. It is written in an easy-to-follow format and with many illustrations to aid clarity and the assimilation of information. Each chapter is written by established authorities in their fields who are also experienced in explaining often complex concepts. The result is a unique book which is not only comprehensive but also clear and useful for the busy medical practitioner.
  • Digital
    P. Marco Fisichella, Fernando A.M. Herbella, Marco G. Patti, editors.
    Springer2016
  • Digital
    Sandra G. Hassink, MD, MS, FAAP.
    AAP ebooks2018
  • Digital
    Mead Over.
    eBook Comp Acad2011
    The global AIDS transition: a feasible objective for AIDS policy -- Using incentives to prevent HIV infections -- Sustaining and leveraging AIDS treatment -- Appendix A. Alternative approaches to estimating the average cost of antiretroviral treatment -- Appendix B. A meta-analysis of the health benefits of early initiation of antiretroviral therapy -- Appendix C. A model for projecting future AIDS treatment costs.
  • Digital
    edited by Gillian Leng, Val Moore, Sasha Abraham.
    Wiley2014
    Practical actions for healthcare providers / Val Moore -- Identifying a high quality evidence base / Paul Chrisp and Sara Twaddle -- Key challenges to implementation and effective interventions / Elaine Whitby and Julie Royce -- Using financial systems to support improved care / Jennifer Field -- Using measurement to support change and improvements in healthcare / Nick Baillie -- Conclusion and reflections / Danny Keenan and Sasha Abraham.
  • Print
    Karl Heinz Burmeister.
    Status: Not Checked Out
    v. 1. Biographie -- v. 2. Bibliographie -- v. 3. Briefwechsel
  • Digital
    Hajo Thermann, Christoph Becher, Michael R. Carmont, Jón Karlsson, Nicola Maffulli, James Calder, C. Niek van Dijk, editors.
    Springer2017
  • Digital
    edited by James A. Nunley.
    Springer2009
  • Digital
    Tony Beshara.
    ProQuest Ebook Central2008Limited to 3 simultaneous users
    Packed with more than 450 sample questions, this book gives job-seekers the guidance they need to get the job they want!
  • Print
    A. Bernard Ackerman, Brigitta M. Cavegn, Mary Jo Robinson, Maria Flordeliz A. Abad-Casintahan.
    Status: Not Checked Out
  • Digital
    Vicente Sanchis-Alfonso, Joan Carles Monllau, editors.
    Springer2013
    "The ACL-Deficient Knee: A Problem Solving Approach, focuses on problem analysis and problem solving, as well as analyzing the possibility of prevention. In each chapter, the biomechanics, anatomy, etc. that are relevant to the topic are reviewed. There are chapters where highly specialized surgical techniques are presented (v. gr. double bundle reconstruction or meniscal transplant), as well as developing areas such as ACL tears in children, where we are finding a growing number of injuries due to the increase of sports at early ages."--publisher's website
  • Digital
    Martha M. Murray, Patrick Vavken, Braden C. Fleming, editors.
    Springer2013
  • Digital
    Frank R. Noyes, Sue D. Barber-Westin, editors.
    Springer2012
    Nearly a million anterior cruciate ligament (ACL) injuries occur each year worldwide, causing long-term problems in the knee joint. This textbook examines the short- and long-term impacts of ACL injuries on the basis of hundreds of published studies. Risk factors for such injuries are explored using data from hypothesis-driven investigations, and possible causes of the higher risk of noncontact ACL injuries in female athletes are analyzed. Neuromuscular training programs shown to reduce the rate of these injuries in female athletes are described in step-by-step detail with the aid of numerous color photographs and video demonstrations. In addition, detailed descriptions are provided for rehabilitation programs to be used after ACL reconstruction in order to reduce the risk of a future injury.
  • Digital
    Frank R. Noyes, Sue Barber-Westin, editors.
    Springer2018
    This book examines the short- and long-term impact of ACL injuries, covering training programs shown to reduce the rate of injuries in female athletes, and post-surgical rehabilitation for reducing the risk of future injury. Includes many color illustrations.
  • Digital
    Mitsuo Ochi, Konsei Shino, Kazunori Yasuda, Masahiro Kurosaka, editors.
    Springer2016
    Part I. Anatomy and Histology of the ACL -- Chapter 1. Functional Anatomy of the ACL Fibers on the Femoral Attachment -- Chapter 2. The Anatomical Features of ACL Insertion Sites and Their Implications for Multi-Bundle Reconstruction -- Chapter 3. Discrepancy Between Macroscopic and Histological Observations -- Chapter 4. Tibial Insertion of the ACL: 3D-CT Images, Macroscopic, and Microscopic Findings -- Chapter 5. Mechanoreceptors in the ACL -- Part II. Biomechanics of the ACL -- Chapter 6. Mechanical Properties and Biomechanical Function of the ACL -- Chapter 7. Biomechanics of the Knee with Isolated One Bundle Tear of the Anterior Cruciate Ligament -- Chapter 8. Function and Biomechanics of ACL Remnant -- Chapter 9. Biomechanics of Single- and Double-Bundle ACL Reconstruction -- Chapter 10. ACL Injury Mechanisms -- Part III. Diagnostics of ACL Injury -- Chapter 11. Physical Examinations and Device Measurements for ACL Deficiency -- Chapter 12. Diagnostics of ACL Injury Using Magnetic Resonance Imaging (MRI) -- Chapter 13. Diagnosis of Injured ACL Using Three-Dimensional Computed Tomography: Usefulness for Preoperative Decision Making -- Part IV. Basic Knowledge of ACL Reconstruction -- Chapter 14. Graft Selection -- Chapter 15. Portal Placement -- Chapter 16. Femoral Bone Tunnel Placement -- Chapter 17. Tibial Bone Tunnel Placement in Double-Bundle Anterior Cruciate Ligament Reconstruction Using Hamstring Tendons -- Chapter 18. Tensioning and Fixation of the Graft -- Chapter 19. Tendon Regeneration after Harvest for ACL Reconstruction -- Chapter 20. Second-Look Arthroscopic Evaluation after ACL Reconstruction -- Chapter 21. Bone Tunnel Changes After ACL Reconstruction -- Chapter 22. Graft I impingement -- Chapter 23. Fixation Procedure -- Part V Multiple bundle ACL Reconstruction -- Chapter 24. Single- vs. Double-Bundle ACL Reconstruction -- Chapter 25. Anatomic Double-Bundle Reconstruction Procedure -- Chapter 26. Triple-Bundle ACL Reconstruction with the Semitendinosus Tendon Graft -- Part VI. ACL Augmentation -- Chapter 27. History and Advantages of ACL Augmentation -- Chapter 28. Surgical Technique of ACL Augmentation -- Part VII. ACL Reconstruction Using Bone-Patella Tendon-Bone -- Chapter 29. An Overview -- Chapter 30. Anatomical Rectangular Tunnel ACL Reconstruction with a Bone-Patellar Tendon-Bone Graft -- Chapter 31. Rectangular vs. Round Tunnel -- Part VIII. Computer-Assisted Navigation in ACL Reconstruction -- Chapter 32. Intraoperative Biomechanical Evaluation Using a Navigation System -- Chapter 33. Application of Computer-Assisted Navigation -- Part IV. ACL Injury in Patients with Open Physes -- Chapter 34. ACL Reconstruction with Open Physes -- Chapter 35. Avulsion Fracture of the ACL -- Part V. Revision ACL Reconstruction -- Chapter 36. Double-Bundle Technique -- Chapter 37. Bone-Patellar Tendon-Bone Graft via Round Tunnel -- Chapter 38. Anatomical Revision ACL Reconstruction with Rectangular Tunnel Technique -- Chapter 39. One- vs. Two-Stage Revision Anterior Cruciate Ligament Reconstruction -- Part VI. Complications of ACL Reconstruction -- Chapter 40. Complications of ACL Reconstruction -- Part VII. Future of ACL Reconstruction -- Chapter 41. Future Challenges of Anterior Cruciate Ligament Reconstruction: Biological Modulation Using a Growth Factor Application for Enhancement of Graft Healing -- Chapter 42. Strategies to Enhance Biological Tendon-Bobe Healing in Anterior Cruciate Ligament Reconstruction -- Chapter 43. Tissue engineering approach for ACL healing.
  • Digital
    Joshua A. Zeichner, editor.
    Springer2014
    Dermatologists commonly treat acne, which affects 40 to 50 million Americans each year and about 85 percent of all patients at some point in their lives. Dermatologists, primary care doctors, and pediatricians see these patients every day in practice. It is important to treat the skin effectively not only to reduce the risk of physical scarring, but also to address the negative psychosocial impact this disease carries. Improving the skin can improve self-confidence, interpersonal relationships, and performance in school or at work. Acneiform Eruptions in Dermatology is a practical, full-color guide to the differential diagnosis of acne vulgaris and the treatment of acne-like conditions. It is organized into sections by subtype of condition (e.g., infections, genetic syndromes, medication-caused) and includes a section of variants of acne that may be misdiagnosed. Within the sections, individual chapters discuss each variant of the condition and begin with a helpful bulleted summary of its defining clinical features. Extensive color clinical images appear throughout the book.
  • Digital
    Corrado Angelini, editor.
    Springer2016
    Foreword -- Introduction -- Part I Diagnosis of acquired myopathies -- Auto-Antibodies in Neuromuscular Disorders -- Electromyography -- Imaging of the Muscle -- Peripheral Nerve Ultrasound -- Magnetic Resonance Imaging of the Peripheral Nerve -- Part II Clinical Entities -- The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis, Necrotizing Myositis and Inclusion Body Myositis -- Necrotising Myopathy -- Statin Myopathy -- Myasthenia Gravis -- Acquired Autoimmune Rippling Muscles with Myasthenia Gravis -- Endocrinological Myopathies -- Vitamin D deficiency in Muscle -- Intensive Care Unit Acquired Weakness -- Part III Neurogenic disorders -- Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy -- GBS Immune Neuropathies -- Amyotrophic Lateral Sclerosis -- Epidemiology and Risk Factors -- Paraneoplastic Diseases of the Peripheral Nervous System -- Diabetic Neuropathy -- Infectious Neuropathies -- Toxic Neuropathies.
  • Digital
    edited by David C. Geary, Daniel B. Berch, Robert J. Ochsendorf, Kathleen Mann Koepke.
    ScienceDirect2017
    Acquisition of Complex Arithmetic Skills and Higher-Order Mathematics Concepts focuses on typical and atypical learning of complex arithmetic skills and higher-order math concepts. As part of the series Mathematical Cognition and Learning, this volume covers recent advances in the understanding of children's developing competencies with whole-number arithmetic, fractions, and rational numbers. Each chapter covers these topics from multiple perspectives, including genetic disorders, cognition, instruction, and neural networks. Covers innovative measures and recent methodological advances in mathematical thinking and learning Contains contributions that improve instruction and education in these domains Informs policy aimed at increasing the level of mathematical proficiency in the general public.
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  • Digital
    Pooya Khan Mohammad Beigi, Emanual Maverakis.
    Springer2015
    1. History of Acrodermatitis Enteropathica -- 2. Epidemiology and Etiology -- 2.1. Epidemiology -- 2.2. Etiology -- 2.2.1. Molecular Etiology of AE -- 2.2.2. Hypothetical Etiology 1: the Alteration of Zinc Bioavailability -- 2.2.3. Hypothetical Etiology 2: a Defective Zinc Transporter -- 2.2.4. Alternative Forms of AE-like Zinc Deficiencies -- 3. Analysis of Disorder -- 3.1. Clinical Forms of AE -- 3.2. Nomenclature of Zinc Deficiencies -- 3.3. Acquired Non-hereditary Zinc Deficiency -- 3.3.1. Zinc Deficient Maternal Breast Milk -- 3.3.2. Zinc Deficient Caused by Metabolism Disorders -- 4. Clinical Symptoms -- 5. Diagnosis -- 5.1. Laboratory Diagnosis of Zinc Deficiency -- 5.2. Histopathology -- 5.3. Biological Diagnosis of AE -- 5.4. Clinical Diagnosis -- 5.5. Molecular Diagnosis -- 5.6. Differential Diagnosis -- 6. Disease Course and Treatment -- 6.1. Treatment -- 7. The Role of Zinc in Different Body Systems -- 7.1. Biochemistry of Zinc Metabolism -- 7.2. Skin and Hair Physiology -- 7.3. Gastrointestinal System and Other Organs -- 7.4. Neurological Development, Growth, and Mental Status -- 7.5. Enzymes -- 7.6. Endocrine System -- 7.7. Metabolism of Nucleic Acids -- 7.8. Mitosis and Meiosis Cycles -- 7.9. Cell Membranes -- 7.10. Synthesis of Proteins and Collagen -- 7.11. Immune System -- 8. History of AE in Adults -- 9. Iranian Hospital Cases in Literature -- 9.1. Patient One -- 9.2. Patient Two -- 9.3. Patient Three -- 9.4. Patient Four -- 9.5. Zinc Deficiency Similarities to AE in Infants (Fifth Patient) -- 10. Clinical Research -- 10.1. Abstract -- 10.2. Synopsis of Study -- 10.3. Purpose of Study -- 10.4. The Considered Hypotheses -- 10.5. Introduction -- 10.5. Methods -- 10.6. Ethical Considerations -- 10.7. Results -- 10.8. Discussion -- 11. Evaluation of Symptoms in Razi Dermatology Hospital -- 12. Case Photos.
  • Digital
    Mt Data Syst1988-
    Dictionary of acronyms, abbreviations, and initialisms.
  • Digital
    [by Laura Skopec].
    In 2014, the American Cancer Society Cancer Action Network (ACS CAN) analyzed coverage of cancer drugs in the health insurance marketplaces created by the Affordable Care Act (ACA) and found that transparency of coverage and cost-sharing requirements were insufficient to allow cancer patients to choose the best plan for their needs. In this updated analysis, we found that coverage transparency has improved somewhat since 2014, but significant barriers remain for cancer patients. To address these barriers, we provide nine recommendations to states and the U.S. Department of Health and Human Services to increase transparency of coverage and cost-sharing, ensure adequate access to medically necessary drugs via an exceptions process, make cost-sharing more predictable and affordable for patients, and monitor the marketplace for evidence of discrimination against persons with high-cost conditions such as cancer.
  • Print
    Ashley, Stanley W.; Souba, Wiley W.; Wilmore, Douglas W.
    Status: Not Checked Out
  • Digital
    Marie-France Carlier, editor.
    Springer2010
    Part 1. Cellular Aspects -- Elementary Cellular Processes Driven by Actin Assembly: Lamellipodia and Filopodia / J. Victor Small and Klemens Rottner -- Coupling Membrane Dynamics to Actin Polymerization / Shiro Suetsugu and Tadaomi Takenawa -- Endocytic Control of Actin-based Motility / Andrea Disanza, Emanuela Frittoli, Chiara Giuliani, Francesca Milanesi and Andrea Palamidessi, et al. -- Actin in Clathrin-Mediated Endocytosis / Marko Kaksonen -- Actin Cytoskeleton and the Dynamics of Immunological Synapse / Viveka Mayya and Michael L. Dustin -- Actin-based Motile Processes in Tumor Cell Invasion / Matthew Oser, Robert Eddy and John Condeelis -- Actin-based Chromosome Movements in Cell Division / Rong Li -- Roles for Actin Dynamics in Cell Movements During Development / Minna Roh-Johnson, Jessica Sullivan-Brown and Bob Goldstein -- Part 2. Molecular Aspects -- Regulation of the Cytoplasmic Actin Monomer Pool in Actin-based Motility / Pekka Lappalainen, Maarit Makkonen and Hongxia Zhao -- From Molecules to Movement: In Vitro Reconstitution of Self-Organized Actin-based Motile Processes / Marie-France Carlier and Dominique Pantaloni -- The WASP-Homology 2 Domain and Cytoskeleton Assembly / Roberto Dominguez -- Formin-Mediated Actin Assembly / David R. Kovar, Andrew J. Bestul, Yujie Li and Bonnie J. Scott -- Visualization of Individual Actin Filament Assembly / Emmanuèle Helfer -- Movement of Cargo in Bacterial Cytoplasm: Bacterial Actin Dynamics Drives Plasmid Segregation / Dyche Mullins -- Part 3. Physical Aspects -- Protrusive Forces Generated by Dendritic Actin Networks During Cell Crawling / Ovijit Chaudhuri and Daniel A. Fletcher -- Mathematical and Physical Modeling of Actin Dynamics in Motile Cells / Anders E. Carlsson and Alex Mogilner -- Force Production by Actin Assembly: Simplified Experimental Systems for a Thorough Modeling / C. Sykes, J. Prost and J.F. Joanny.
  • Digital
    Cristobal G. dos Remedios, Deepak Chhabra, editors.
    Springer2008
  • Digital
  • Digital
    volume editors, H. Peter Soyer, Tarl W. Prow, Gregor B.E. Jemec.
    Karger2015
    Epidemiology of actinic keratosis / Green, A.C -- Patients' perspectives on actinic keratosis / Esmann, S. -- Photodamage : all signs lead to actinic keratosis and early squamous cell cancer / Wei, J.; Kok, L.F.; Byrne, S.N.; Halliday, G.M. -- Dysregulation of epidermal growth factor receptor in actinic keratosis and squamous cell carcinoma / Joseph, S.R.; Munoz, L.; Gaffney, D.C.; Saunders, N.A.; Simpson, F. -- The actinic keratosis virome : can we prevent squamous cell carcinoma with a vaccine? / Frazer, I.H. -- Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile? / Wells, J.W. -- Mouse models for actinic keratosis and squamous cell carcinoma / Handoko, H.Y.; Ferguson, B.; Walker, G.J. -- Keratinocyte cancer and its precursors in organ transplant patients / Jenni, D.; Hofbauer, G.F.L. -- Clinical features of actinic keratoses and early squamous cell carcinoma / Wheller, L.; Soyer, P. -- The many clinico-pathologic faces of actinic keratosis : an atlas / Massone, C.; Cerroni, L. -- Dermoscopy of actinic keratosis, intraepidermal carcinoma and squamous cell carcinoma / Zalaudek, I.; Argenziano, G. -- The future of keratinocyte skin cancer surveillance : automated image analysis to identify and monitor keratinocyte dysplasia / Hames, S.C.; Prow, T.W. -- Reflectance confocal microscopy : hallmarks of keratinocyte cancer and its precursors / Prow, T.W.; Tan, J.-M.; Pellacani, G. -- Optical coherence tomography and its role for delineating the thickness of keratinocyte dysplasia and neoplasia / Themstrup, L.; Jemec, G.B.E. -- Teledermatology : its use in the detection and management of actinic keratosis / Janda, M. -- Conventional treatment of actinic keratosis : an overview / Peris, K.; Fargnoli, M.C. -- Field cancerization : from molecular basis to selective field-directed management of actinic keratosis / Philipp-Dormston, W.G. -- Update on photodynamic treatment for actinic keratosis / Wiegell, S.R. -- Laser treatment and its implications for photodamaged skin and actinic keratosis / de Vries, K.; Prens, E.P. -- Ingenol mebutate : from common weed to cancer cure / Zarchi, K.; Jemec, G.B.E. -- Oral nicotinamide and actinic keratosis : a supplement success story / Kim, B.; Halliday, G.M.; Damian, D.L.
  • Digital
    Chang-Hwei Chen.
    Springer2012
  • Digital
    J.J. McComb, R. Norman, M. Zumwalt (eds.).
    Springer2014
    The purpose of the The Active Female: Health Issues Throughout the Lifespan, 2nd Edition is twofold: (1) to increase the awareness of wellness and fitness issues for active females and their family members; and (2) to provide an avenue for medical practitioners, allied health professionals, health educators, and certified individuals in sports medicine to gain critical, updated knowledge of a field specific to active females. Part I of the book offers a foundation to help the reader understand the interrelationship among body image concerns, the female reproductive cycle, and musculoskeletal anatomy/physiology of females that makes their health risks and concerns unique. Reproductive health is discussed by a prominent researcher in reproduction/endocrinology. An overview of the Female Athlete Triad which is a syndrome of three interrelated conditions (isordered eating, menstrual disturbances and bone loss) is presented in Part II. Physicians and certified professionals in sports medicine discuss the individual components of the triad, relating not only to the athletic female but also to the recreationally active woman throughout the lifespan. In Part III, Prevention and management of common musculoskeletal injuries is addressed by a female orthopedic surgeon who sub-specializes in treating female athletes. Finally, appropriate exercise and nutritional guidelines for active females are discussed in Parts IV-V of the book by certified professionals and licensed physicians in sports medicine. An invaluable addition to the literature, The Active Female: Health Issues Throughout the Lifespan, 2nd Edition will be of great interest to physicians, allied health care practitioners, medical/other wellness educators, and students who are interested in advancing women's health issues. Sports medicine specialists, family practitioners, gynecologists, team physicians, residents in sports medicine, athletic trainers, health educators, nurses, physicians assistants, physical therapists, sport psychologists, counselors, athletic trainers, and other members of the sports medicine team should also find this title of significant interest.
  • Digital
    volume editor, Klaus Böheim.
    Karger2010
    The vibrant soundbridge : design and development / Ball, G.R. -- Cost-effectiveness of implantable middle ear hearing devices / Snik, A. ... [et al.] -- Indications and candidacy for active middle ear implants / Wagner, F. ... [et al.] -- Clinical results with an active middle ear implant in the oval window / Hüttenbrink, K.B., Beutner, D., Zahnert, T. -- Experiments on the coupling of an active middle ear implant to the stapes footplate / Zahnert, T., Bornitz, M., Hüttenbrink, K.B. -- The vibrant soundbridge for conductive and mixed hearing losses : European multicenter study results / Baumgartner, W.-D. ... [et al.] -- Clinical experience with the active middle ear implant vibrant soundbridge in sensorineural hearing loss / Pok, S.M., Schlögel, M., Böheim, K. -- The esteem system : a totally implantable hearing device / Maurer, J., Savvas, E. -- Totally implantable active middle ear implants : ten years' experience at the University of Tübingen / Zenner, H.P., Rodriguez Jorge, J.
  • Digital
    Active Shooter events are becoming increasingly more common, and while there have been recommendations on how to respond since 2008, these guidelines focused on schools, government, and business settings. In January of 2014, the HPH SCC released "Active Shooter Planning and Response in a Healthcare Setting". That draft document was the first comprehensive guidance written for healthcare facilities to prevent, respond to, and recover from an active shooter event. This updated document expands upon the initial draft document to include law enforcement tactics and integrated medical and mental health response.
  • Digital
    Laurence Klotz, editor.
    Springer2012
  • Digital
    Laurence Klotz, editor.
    Springer2018
  • Print
    Benjamin F. Cravatt, Ku-Lung Hsu, Eranthie Weerapana, editors.
    "This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions."--Publisher's description.
  • Digital
    edited by Herman S. Overkleeft and Bogdan I. Florea, Bio-Organic Synthesis Group, Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands.
    Springer2017
    This volume focuses on explorative activity-based proteomics, biomedical applications of activity-based proteomics, and chemical strategies in activity-based proteomics providing a concise overview of activity-based protein profiling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Activity-Based Proteomics: Methods and Protocols aims to ensure successful results in the further study of this vital field.-- Source other than the Library of Congress.
  • Print
    Soulié, Charles Georges.
    Status: Not Checked Out
    I. L'énergie (points, méridiens, circulation) -- II. Le maniement de l'énergie.
  • Digital
    William C.S. Cho, editor.
    Springer2012
  • Digital
    Yuan Chi Lin, Eric Hsu, editors.
    Springer2014
    Acupuncture for Pain Management is intended as the premier resource for learning the fundamentals of the art of medical acupuncture. Edited by top pain medicine specialists at Harvard and UCLA, and based on their popular annual workshop at the American Society for Anesthesiologists, the book is the perfect synthesis of Western and Chinese medicine. Anesthesiologists, pain medicine specialists, primary care physicians, osteopaths, neurologists, psychiatrists, physical medicine and rehabilitation specialists, and other health professionals looking to add acupuncture to their repertoire will benefit from the concise and practical approach of the book. Features: Each individual meridian discussed in detail acupuncture for 25 clinical conditions, including headache, menstrual pain, low back pain, insomnia, and more. Aimed at acupuncturists as well as practitioners who want to add acupuncture to their clinical armamentarium.
  • Digital
    edited by Jennie Longbottom.
    ScienceDirect2010
    Acupuncture in Manual Therapy is a comprehensive overview of manual therapy interventions combined with acupuncture management of musculo-skeletal disorders covering all major joints of the body. The book is intended to offer physiotherapists and students of acupuncture a clinical reasoning model, whilst supporting suggested interventions with the relevant evidence base in order to alleviate pain, restore function and facilitate rehabilitation within musculo-skeletal management. It places an emphasis on the neurophysiological processes of pain management stressing the importance of using the correct intervention for the relevant presenting pain mechanism. Each chapter discusses suggested manual intervention, acupuncture evidence and physiological processes underpinning this combined approach to musculo-skeletal pain and dysfunction including meridian acupuncture, auricular acupuncture, electroacupuncture, tens and trigger point acupuncture as a means of addressing the varying pain patterns presented within musculo-skeletal rehabilitation. This book provides knowledge from distinctive and prominent contributors from the world of manual therapy and acupuncture. This expertise is further supported by the provision of student case studies to offer support and enhance learning. --Book Jacket.
  • Digital
    Val Hopwood, Clare Donnellan.
    ScienceDirect2010
    History and background of traditional Chinese medicine in neurological conditions -- Researching a complex intervention -- Current context : neurological rehabilitation and neurological physiotherapy -- Western medical acupuncture in neurological conditions -- Practical application of western medical acupuncture in neurological conditions -- Acquired brain injury : stroke, cerebral palsy, and traumatic brain injury -- Parkinson's disease and related conditions -- Multiple sclerosis -- Spinal cord injury and disease -- Peripheral nervous system disorders -- Motor neurone disease -- Pulling it together.
  • Digital
    Ying Xia, Xiaoding Cao, Gencheng Wu, Jieshi Cheng [editors].
    Springer2010
  • Digital
    Goran Augustin.
    Springer2014
    Part I. Surgery -- 1. Acute Appendicitis -- 2. Acute Biliary Tract Diseases -- 3. Acute Pancreatitis -- 4. Nontraumatic Gastroduodenal Perforations -- 5. Symptomatic Abdominal Wall Hernias -- 6. Symptomatic Diaphragmatic Hernia -- 7. Intestinal Obstruction -- 8. Acute Inflammatory Bowel Disease -- 9. Spleen -- 10. Abdominal Trauma -- 11. Miscellaneous Conditions -- Part II. Gynecology -- 12. Adnexal Torsion -- 13. (Isolated) Torsion of the Fallopian Tube -- 14. Ruptured/Bleeding Ovarian Cysts/Tumors -- 15. Ruptured Ectopic Pregnancy -- 16. Spontaneous Uterine Rupture -- 17. Torsion of the Gravid Uterus -- 18. Degenerating Uterine Myomas -- 19. Pelvic Inflammatory Disease and Tubo-ovarian Abscess.
  • Digital
    Goran Augustin.
    Springer2018
    This book will help readers recognize, diagnose and efficiently treat acute abdominal disorders encountered in the pregnant patient, whether associated with or incidental to the pregnancy. Includes more than 200 figures relevant to diagnosis and treatment.
  • Digital
    Grégoire Chick, editor.
    Springer2013
    Neglected finger injuries may lead to chronic lesions that often have detrimental consequences for the practice of a ball sport, whether at a recreational level or at the top athlete level. The initial injury management is crucial. Depending on the type and the severity of the lesions, different people may get involved: the players themselves or their entourage, physiotherapists, club doctors, emergency physicians, family doctors, sports doctors or hand surgeons. Treatment is usually conservative: the long fingers require rapid mobilization to prevent stiffness and contrary to that, the thumb requires stability. Surgery may be necessary to reach these goals especially for athletes, because of the demands of their sport. Chronic lesions are also in part related to repeated trauma, requiring specialized long-term multidisciplinary treatment. They can often lead to the end of a sporting career, but also may limit the functionality of the fingers at the time of conversion.
  • Digital
    edited by Claire Colebourn, Jim Newton.
    Oxford Medicine Online2017
    This is a comprehensive practical guide to the practice of the new subspecialty of critical care echocardiography. The text covers all aspects of clinical practice and describes how to use transthoracic echocardiography to approach and manage common clinical questions. Specific emphasis is placed on the appropriate use of clinical echocardiographic data in the context of the patient's critical illness; this is illustrated by the frequent use of case studies including both still and moving echocardiographic images. The text covers assessment of, and disorders affecting, the left and right heart, including shock and sepsis. It also looks at how to interpret diastolic information during critical illness and the effect of that illness on valve disease and function. The important subject of fluid responsiveness is explored in detail, as is the influence of organ support and illness on the diagnosis of cardiac tamponade. The information given in the text is summarized using algorithms in a field guide for the critical care echocardiographer, which also provides a rapid guide to assessing time-critical patient presentations.
  • Digital
    Joseph Varon, MD, FACP, FCCP, FCCM, University of Texas Health Science Center, Houston, TX, USA, Robert E. Fromm, Jr., MD, MPH, FACP, FCCP, FCCM, University of Arizona College of Medicine, Phoenix, AZ, USA.
    Springer2014
    This pocket guide is a single-volume source of the most common and important formulas and laboratory values used in the daily practice of acute care and critical care medicine. Information is presented in outline format and as tables, graphics, and algorithms to facilitate quick look up. Acute and Critical Care Formulas and Laboratory Values is designed to help clinicians interpret clinical data, apply formulas, understand laboratory values, and integrate this information with their knowledge of pathophysiology to promote the delivery of evidence-based care. Essential formulas and laboratory values. Multiple ways to derive a value, where appropriate. Non-clinical formulas useful for understanding physiologic concepts or that underlie diagnostic tests or clinical measurement.
  • Digital
    volume editors, Hiromichi Suzuki, Hiroyuki Hirasawa.
    Karger2010
    "Describes the use of hemodiafiltration to inhibit the cytokine storms which cause serious organ damage in patients with septic shock. Moreover, the technical construction of the blood purification system, which includes various machines, devices, membranes, fluids, etc., is explained in detail. Finally, leading experts discuss the concept of continuous renal replacement therapy as the standard care in critically ill patients with severe acute kidney injury."--Website.
  • Print
    edited by Anish Bhardwaj, Dilantha B. Ellegala, Jeffrey R. Kirsch.
    Status: Not Checked Out
    Decompressive hemicraniectomy for large hemispheric infarctions / Eric Jüttler, Alfred Aschoff, and Stefan Schwab -- Anticoagulation in ischemic stroke / Carolyn A. Cronin and Robert J. Wityk -- Angioplasty and stenting of cervical carotid, intracranial, and vertebral arteries / Aclan Dogan ... [et al.] -- Neuromonitoring in ischemic stroke / Kairash Golshani, Emun Abdu, and Anish Bhardwaj -- Surgical evacuation of intracerebral hemorrhage / Patrick C. Hsieh ... [et al.] -- Management of blood pressure and intracranial hypertension in intracerebral hemorrhage / Gustavo J. Rodríguez, Qaisar A. Shah, and Adnan I. Qureshi -- Decompressive hemicraniectomy in the management of severe traumatic brain injury / Ian F. Dunn and Dilantha B. Ellegala -- Cerebroprotective strategies in bedside management of traumatic brain injury / Ganesh M. Shankar, Ian F. Dunn, and Dong H. Kim -- Diffuse axonal injury and dysautonomia / Richard H. Singleton, David O. Okonkwo, and P. David Adelson -- Neuromonitoring in traumatic brain injury / Rene Celis and Claudia S. Robertson -- Hypothermia and pharmacologic coma in the treatment of traumatic brain injury / Gordon Li ... [et al.] -- Pediatric traumatic brain injury / Zachary N. Litvack and Nathan R. Selden -- Diagnostic evaluation of aneurysmal subarachnoid hemorrhage / Jonathan A. Edlow -- Surgical versus endovascular aneurysmal exclusion / Aaron W. Grossman, Anil V. Yallapragada, and Giuseppe Lanzino -- Diagnosis and medical management of vasospasm and delayed cerebral ischemia / Olga Helena Hernandez and Jose I. Suarez -- Pharmacologic cerebroprotection in aneurysmal subarachnoid hemorrhage / Yekaterina Axelrod, Salah Keyrouz, and Michael N. Diringer -- Use of anticonvulsants and corticosteroids in SAH / Panayiotis N. Varelas and Lotfi Hacein-Bey -- Management of electrolyte and metabolic derangements in subarachnoid hemorrhage / Tarik Hanane and Eelco F.M. Widjicks -- Management of cardiopulmonary dysfunction in subarachnoid hemorrhage / Thomas P. Bleck -- Neuroradiologic interventional procedures for cerebral vasospasm / Pascal M. Jabbour, Erol Veznedaroglu, and Robert H. Rosenwasser -- Intraoperative management of spinal cord injury / Dawn Dillman and Ansgar Brambrink -- Medical management of acute spinal cord injury / Steven Casha and R. John Hurlbert -- Pediatric spine injury / Brian Jankowitz, David O. Okonkwo, and Christopher Shaffrey.
  • Digital
    edited by David Chelmow, Leo J. Dunn Professor and Chair, Virginia Commonwealth University School of Medicine, Richmond, VA, USA, Christine R. Isaacs, Associate Professor and Director, General Obstetrics and Gynecology Division, Medical Director of Midwifery Services, Virginia Commonwealth University School of Medicine, Richmond, VA, USA, Ashley Carroll, Assistant Professor, Department of Obstetrics and Gynecology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
    Cambridge2015
    Section I. General gynecology : -- 1. A 45-year-old woman with heavy vaginal bleeding / Tod C. Aeby -- 2. A 29-year-old woman with a pelvic mass and altered mental status / Saweda A. Bright and Stephen A. Cohen -- 3. Acute exacerbation of chronic pelvic pain in a 32-year-old woman / Lee A. Learman -- 4. A 19-year-old woman with diabetes and hypertension requiring emergency contraception / David Chelmow -- 5. Bleeding, pain, and fever four days after first-trimester termination / Erin L. Murata and Tony Ogburn -- 6. A 25-year-old woman requesting emergency contraception / Reni A. Soon and Tod C. Aeby -- 7. Persistent trichomonas infection / Lilja Stefansson -- 8. A 42-year-old woman with recurrent unexplained vaginitis symptoms / Chemen M. Tate -- 9. A 30-year-old woman with vaginal itching / Lindsay H. Morrell -- 10. Sudden-onset left lower quadrant pain in a 21-year-old woman / Adrianne M. Colton -- 11. A 35-year-old woman with IUD string not visible / Michelle Meglin -- 12. A 38-year-old woman with sudden-onset shortness of breath / Chris J. Hong and David Chelmow -- 13. Vaginal bleeding in a 75-year-old woman / K. Nathan Parthasarathy and Peter F. Schnatz -- 14. A 60-year-old woman with severe vulvar itching and an ulcer / Alan G. Waxman -- 15. Urinary retention in a 19-year-old woman / Amanda B. Murchison and Megan Metcalf -- 16. Recurrent herpes infection in a 28-year-old woman / Breanna Walker -- 17. Vulvar infection and sepsis in a 42-year-old woman / L. Chesney Thompson -- 18. A 42-year-old woman with irregular bleeding / Alison F. Jacoby -- 19. Persistent HSV in an HIV-positive woman / Jennifer A. Cross -- 20. Incidentally discovered vaginal cyst in a 34-year-old woman / Roger P. Smith -- 21. A 45-year-old woman with an enlarging pelvic mass / Alison F. Jacoby -- 22. A 23-year-old woman with pelvic pain and fever / C. Nathan Webb -- 23. A 21-year-old woman with a new sexual partner / Elizabeth M. Yoselevsky and Christine R. Isaacs -- 24. A 21-year-old woman with persistent pain and fever after treatment for PID / Nicole S. Fanning -- 25. Acute vaginal and abdominal pain after defecation in a 79-year-old woman / Heidi J. Purcell and Laurie S. Swaim -- 26. Tachycardia and vaginal bleeding in pregnancy / Kimberly Woods McMorrow 27 Vaginal spotting at eight weeks' gestation { Amanda B. Murchison and Melanie D. Altizer -- 28. Heavy bleeding after medical management of a missed abortion / Elizabeth L. Munter -- 29. Abdominal pain and vaginal bleeding in a 24-year-old woman / Jessica M. Ciaburri -- 30. Unanticipated ultrasound findings at follow-up prenatal visit / Nikola Alexander Letham and Christopher Morosky -- 31. Early pregnancy spotting and an unusual ultrasound / Michelle Meglin -- 32. Undesired pregnancy in a 19-year-old woman / Megan L. Evans and Danielle Roncari -- 33. A pregnant 37-year-old woman with lower left quadrant pain / Rajiv B. Gala -- 34. Unruptured advanced ectopic pregnancy / Ellen L. Brock -- 35. A 23-year-old pregnant woman with acute-onset abdominal pain and hypotension / Rachel K. Love and Nicole Calloway Rankins -- 36. A woman with first-trimester vaginal bleeding / Valerie L. Williams and Amy E. Young -- 37. Midcycle spotting and worsening menorrhagia / Patricia S. Huguelet -- 38. A 40-year-old woman on tamoxifen therapy with a uterine mass / Megan A. Brady -- 39. Small mass prolapsing from the cervix found on routine pelvic examination / John G. Pierce Jr -- 40. A 35-year-old woman with a painful vulvar mass / Philippe Girerd -- 41. A 32-year-old woman urgently referred for a cervical mass noted on routine pelvic examination / Christopher A. Manipula -- 42. An 18-year-old woman with long-acting reversible contraception and new-onset bleeding / Jennifer Salcedo and Aparna Sridhar -- 43. Cyclic pain after endometrial ablation / Ellen L. Brock -- 44. Positive hCG in a patient who reports no sexual activity for one year / Roger P. Smith -- 45. Recalcitrant severe vaginal discharge and odor / Amber Price -- 46. A 25-year-old woman with a painful vulvar mass / Nan G. O'Connell -- 47. Acute abdominal pain two weeks after successful vaginal birth after Cesarean / Kathryn Shaia and Christine R. Isaacs -- 48. A 64-year-old woman with a simple ovarian cyst / John W. Seeds -- 49. A 26-year-old woman with acute pelvic pain and free fluid in the pelvis / Isaiah M. Johnson and Adrienne L. Gentry -- 50. A 36-year-old woman with fever and pelvic pain at 14 weeks' gestation / Frances Casey and Katie P. Friday -- 51. Acute fever and tachycardia in a 21-year-old woman during laparoscopy / Thomas C. Peng -- 52. A 40-year-old woman with hypertension and first-trimester bleeding / Fidelma B. Rigby and Angela M. Tran -- -- Section II. Pregnancy : -- 53. Nausea and vomiting at eight weeks' gestation / Brian Bond and Ashley Peterson -- 54. A 27-year-old woman with severe nausea and vomiting in pregnancy / Sarah Peterson -- 55. Early pregnancy with vaginal spotting / Kathryn A. Houston and Sarah B. Wilson -- 56. Positive RPR on initial prenatal labs / Ronald M. Ramus -- 57. A high-speed motor vehicle accident during pregnancy / Susan M. Lanni -- 58. A 32-year-old woman with fever and unilateral breast pain / Meghann E. Batten -- 59. A 36-year-old woman with nipple pain postpartum / Julie Zemaitis DeCesare and Karen Shelton -- 60. A woman in first-trimester pregnancy with fever, malaise, nausea, and vomiting / Saweda A. Bright and Susan M. Lanni -- 61. First-trimester flu-like symptoms in a 31-year-old woman / Lilja Stefansson and Susan M. Lanni -- -- Section III. Reproductive endocrinology and infertility : -- 62. Abdominal pain and distension seven days after egg retrieval for planned IVF / Richard Scott Lucidi -- 63. Irregular bleeding in a 39-year-old nulliparous woman desiring fertility / PonJola Coney -- 64. A 24-year-old woman with her third pregnancy loss / Richard Scott Lucidi -- 65. A 38-year-old woman with worsening postpartum fatigue / Amanda H. Ritter -- 66. A 19-year-old woman with primary amenorrhea / Amy Brown and Nicole W. Karjane -- 67. A 26-year-old woman with secondary amenorrhea / Mary T. Sale and Nancy A. Sokkary -- 68. Irregular bleeding in a 25-year-old woman / Anita K. Blanchard -- 69. A 28-year-old woman with irregular bleeding requiring transfusion / Ronan A. Bakker -- 70. A 29-year-old woman with secondary amenorrhea after a septic abortion / Nancy D. Gaba and Gaby Moawad -- -- Section IV. Pediatric and adolescent gynecology : -- 71. Worsening dysmenorrhea in a 14-year-old girl / Nicole W. Karjane -- 72. A seven-year-old girl with vaginal bleeding / Nicole W. Karjane -- 73. A four-year-old girl falls while exiting the bathtub / Sarah H. Milton and Elisabeth McGaw -- 74. Worsening cyclic pain and amenorrhea in a 13-year-old girl / Sarah H. Milton -- 75. Worsening cyclic pain and amenorrhea in a 13-year-old girl with a normal appearing but short vagina / Nicole W. Karjane -- 76. A 19-month-old girl with labial adhesions and acute urinary retention / Hong-Thao Thieu and Meredith S. Thomas -- 77. A 13-year-old girl with irregular menses and significant weight gain / Tiffany Tonismae and Eduardo Lara-Torre -- 78. A 14-year-old girl with anemia / Layson L. Denney and Sarah H. Milton -- 79. A 13-year-old girl with vulvar irritation and new-onset behavioral problems / Meredith Gray and Eduardo Lara-Torre -- 80. A 10-year-old girl with lower abdominal pain / Lisa Rubinsak and Ellen L. Brock -- -- Section V. Urogynecology : -- 81. Complete procidentia in a 70-year-old woman / Jordan Hylton and Saweda A. Bright -- 82. Incontinence in a 50-year-old woman after pessary placement / Tanaz R. Ferzandi -- 83. A periurethral mass in a 25-year-old woman / Barbara L. Robinson -- 84. A periurethral mass in a 45-year-old woman / Andrew Galffy and Christopher Morosky -- 85. New-onset incontinence in a 42-year-old woman / Tanaz R. Ferzandi -- 86. Urinary leakage following hysterectomy / Edward J. Gill -- 87. Urinary retention following urethral sling surgery / Edward J. Gill -- 88. A urethral mass in a postmenopausal woman / Audra Jolyn Hill -- -- Section VI. Gynecologic oncology : -- 89. A 70-year-old woman with a new vulvar mass / Weldon Chafe -- 90. A 45-year-old woman with a fungating cervical mass / Jori S. Carter -- 91. A 48-year-old woman with a 4-month history of intermittent abdominal pain and urinary frequency / Kirk J. Matthews and Jori S. Carter -- 92. A 65-year-old woman with profuse vaginal bleeding / Amy Hempel and Jori S. Carter -- 93. A 38-year-old woman with heavy vaginal bleeding 6 months after D & C for complete mole / Emily E. Landers and Warner K. Huh -- 94. A 62-year-old woman with a vulvar lesion / Megan M. Shine and Warner K. Huh -- 95. A 62-year-old woman with ovarian cancer and new-onset pelvic and right-leg pain / Kirk J. Matthews -- 96. A 64-year-old woman with ovarian cancer, emesis, and abdominal pain / Nguyet A. Nguyen and Warner K. Huh -- 97. A 65-year-old woman with new-onset fatigue, parasthesias, and muscle cramps after chemotherapy for ovarian cancer / Haller J. Smith and Warner K. Huh.
  • Digital
    Michael L. Malone, Elizabeth A. Capezuti, Robert M. Palmer, editors.
    Springer2014
    1. An Introduction to the Acute Care for Elders / Michael L. Malone, Ji Won Yoo, and James S. Goodwin -- 2. The Team Approach to Interdisciplinary Care / Maryjo Cleveland, Carolyn Holder, Ariba Khan, and Aileen Jencius -- 3. Patient and Hospital Factors That Lead to Adverse Outcomes in Hospitalized Elders / Edgar Pierluissi, Deborah C. Francis, and Kenneth E. Covinsky -- 4. An Overview of Hospital-Based Models of Care / Elizabeth A. Capezuti and Marie Boltz -- 5. The Acute Care for Elders Unit / Robert M. Palmer and Denise M. Kresevic -- 6. How to Develop, Start, and Sustain an Acute Care for Elders Unit / Ellen S. Danto-Nocton, Carolyn Holder, Rebecca Ramsden, Jonny Macias Tejada, Anita Steliga, and Karen Padua -- 7. How to Disseminate the ACE Model of Care Beyond One Unit / Roger Y. Wong, Marsha Vollbrecht, and Patti Pagel -- 8. How to Use the ACE Unit to Improve Hospital Safety and Quality for Older Patients: From ACE Units to Elder-Friendly Hospitals / Samir K. Sinha, Sandra Liliana Oakes, Selma Chaudhry, and Theodore T. Suh -- 9. ACE Unit Business Model / Kyle Allen, Peter DeGolia, Susan Hazelett, and Diane Powell -- 10. Models of Care to Transition from Hospital to Home / Ella Harvey Bowman, Kellie L. Flood, and Alicia I. Arbaje -- 11. What Is the Role of Hospitalists in the Acute Care for Elders? / Heidi L. Wald and Melissa L. P. Mattison -- 12. How to Improve Care for Seniors in the Emergency Department / Soryal Soryal, Marie Boltz, Scott Wilber, and Michael L. Malone -- 13. How to Improve Care for Older Patients in the Intensive Care Unit / Leanne Boehm, E. Wesley Ely, and Lorraine Mion -- 14. The Future of Acute Care for Elders / Kanwardeep Singh and Michael L. Malone.
  • Digital
    Dale A. Dangleben, Firas G. Madbak, editors.
    Springer2017
    Acute Care General Surgery provides a succinct focused overview of a myriad of general surgical emergencies. Each chapter has a concise, practical framework on the workup and management of a specific topic. The book covers a wide array of pathology from the more common appendicitis, diverticulitis and cholecystitis to those less frequently encountered such as toxic megacolon, Fournier's gangrene and volvulus. Learning objectives for each chapter are clearly defined. In addition to differential diagnosis, the work up and management is comprehensively discussed. In addition, a pithy clinical pearl is included to serve as a memory aid for each diagnosis. Upon reviewing this volume, clinicians who encounter the acute care surgical patient in their practices will be better equipped to rapidly assess, evaluate, diagnose and managing their complex and often challenging problems.
  • Digital
    Jaime C. Paz, Michele P. West.
    ScienceDirect2014
    Part 1. Introduction -- 1. Acute Care Setting -- 2. The Medical Record -- Part 2. Body Systems -- 3. Cardiac System --4. Pulmonary System -- 5. Musculoskeletal System -- 6. Nervous System -- 7. Vascular System and Hematology -- 8. Gastrointestinal System -- 9. Genitourinary System -- 10. Endocrine System -- Part 3. Diagnoses -- 11. Oncology -- 12. Burns and Wounds -- 13. Infectious Diseases -- 14. Organ Transplantation -- 15. Fluid and Electrolyte Imbalances -- 16. Amputation -- 17. Physical Therapy Considerations for Patients Who Complain of Chest Pain -- Part 4. Interventions -- 18. Medical-Surgical Equipment in the Acute Care Setting -- 19. Pharmacologic Agents -- 20. Anesthesia: Perioperative Considerations for the Physical Therapist -- 21. Acute Pain Management -- 22. Postural Drainage -- 23. Functional Tests -- Appendix A. Preferred Practice Patterns.
  • Print
    [edited by] Cynthia C. Chernecky, Kathleen Murphy-Ende.
    Status: Not Checked Out
    Acute pancreatitis / Jean Ellsworth-Wolk -- Acute respiratory distress syndrome / Mercedes K. Young -- Malignant ascites / Deborah Murphy -- Bronchitis obliterans / Laura Milligan and Yvonne D. Martin -- Cardiac tamponade and pericardial effusions / Brenda K. Shelton -- Carotid artery rupture / Catherine Sargent -- Cognitive dysfunction / Nancy Jo Bush -- Depression and anxiety / Nancy Jo Bush -- Diabetes insipidus / Jennifer U. Varma -- Diabetes mellitus / Timothy L. Wren and Kathleen R. Wren -- Disseminated intravascular coagulation (DIC) / Brenda K. Shelton -- Dyspnea and airway obstruction / Cynthia C. Chernecky and Libby Montoya -- End-of-life care / Cynthia Brown and Kathleen Murphy-Ende -- Esophageal varices / Lori Ann Brown -- Ethics in adult oncology and critical care nursing / Marlene M. Rosenkoetter -- Fever / Angela L. Daniel -- Gastrointestinal obstruction : biliary, gastric, and bowel obstructions / Kathleen Murphy-Ende -- Graft versus host disease / Jill K. Burleson -- Heart failure / Jacqueline R. Gannuscio -- Hemorrhage secondary to cervical cancer / Brenda K. Cobb and Cynthia C. Chernecky -- Hemorrhagic cystitis / Cathy Fortenbaugh -- Hepatic encephalopathy / Kathleen Murphy-Ende -- Tumor-induced hypercalcemia / Kathryn E. Pearson -- Hyperkalemia / Mary Pat Lynch -- Hyperleukocytosis in childhood leukemia / Kristin Casey -- Hypernatremia / Mady Stovall -- Hypersensitivity reactions to chemotherapy / Teresa Kuntzsch and Cassie A. Voge -- Hyperurecemia / Libby Montoya -- Hypokalemia / Mary Pat Lynch -- Hypomagnesemia / Lyle Stuart Baker, Jr., Brenda K. Shelton, and Michael I. Agugo -- Hyponatremia / Cynthia C. Chernecky, Demica N. Jackson, and Angela L. Daniel -- Increased intracranial pressure / Kara L. Penne -- Lactic acidosis, type B / Catherine Sargent -- Lambert-Eaton myasthenic syndrome / Dionne T. Savage -- Malnutrition and cachexia / Kathy G. Kravits and Marcia Grant -- Pain management : nociceptive and neuropathic / Christine Miaskowski -- Pathological fractures / Cynthia C. Chernecky -- Pleural effusions : malignant / Diane G. Cope -- Pulmonary fibrosis / Cynthia C. Chernecky -- Seizures / Mary P. Lovely -- Sepsis and septic shock / Kathy A. Shane -- Sinusoid occlusive syndrome / Patricia C. Buchsel -- Spinal cord compression / Christine Miaskowski -- Spiritual distress in people with cancer / Martha Meraviglia, Carol D. Gaskamp, and Rebecca R. Sutter -- Suicidal ideation / Kathleen Murphy-Ende -- Superior vena cava syndrome / Molly Loney and Nancy Kelly -- Syndrome of inappropriate antidiuretic hormone (SIADH) / Jeanne Held-Warmkessel -- Tumor lysis syndrome / Brenda K. Shelton -- Typhlitis in pediatrics / Kaci L. Osenga.
  • Digital
    [edited by] L.D. Britt, Andrew B. Peitzman, Philip S. Barie, Gregory J. Jurkovich.
    Ovid2019
    "Substantially updated with more illustrations and brand-new chapters that reflect the growth and advances in the field, this latest edition of Acute Care Surgery features an editorial board drawn from the ranks of trauma surgery, emergency surgery, and critical care surgery. A comprehensive, updated, and timely overview of this fledgling specialty!"--Provided by publisher.
  • Digital
    [edited by] Kathryn L. Butler ; associate editor, Mukesh Harisinghani.
    AccessSurgery2015
    Section I. Radiology basics -- Section II. Abdomen -- Section III. Chest -- Section IV. Soft tissue -- Section V. Trauma.
  • Digital
    Salomone Di Saverio, Fausto Catena, Luca Ansaloni, Federico Coccolini, George Velmahos, editors.
    Springer2017
    This pocket manual is a practically oriented, wide-ranging guide to acute care surgery general aspects and℗ℓto non-gastrointestinal emergencies. It covers the most common problems in thoracic, obstetric, gynecologic, anorectal, vascular and skin surgery and also includes chapters on postoperative complications in bariatric surgery, antibiotic management, nutrition and interventional radiology in acute care surgery. This guide stems from collaboration with the World Society of Emergency Surgery (WSES) and aims to provide general surgeons, ℗ℓresidents and trainees with a comprehensive and up-to-date overview℗ℓof the℗ℓmost relevant operative techniques and with useful℗ℓ "tips and tricks" applicable in daily clinical practice. A second volume on gastrointestinal and abdominal surgical emergencies is also available.
  • Digital
    Soumitra R. Eachempati, R. Lawrence Reed, II, editors.
    Springer2015
  • Digital
    Mun K. Hong and Eyal Herzog (eds.).
    Springer2008
  • Digital
    [edited by] Pierre Theroux.
    ClinicalKey2011
    Acute Coronary Syndromes-a Companion to Braunwald₂s Heart Disease-covers the state-of-the-art scientific and clinical information you need to rapidly evaluate and manage acute coronary syndromes. Dr. Pierre Theroux and his team of expert contributors present advances in diagnostic and imaging techniques such as biomarkers, nuclear cardiology, echocardiography, and multislice CT; secondary prevention; and new antiplatelet, anti-ischemic, and gene therapies. Tap into the most definitive knowledge available from one of the leading experts in the field and a stellar cast of contributors. Understand the special considerations for the care of acute coronary syndromes in the emergency department and the coronary care unit. Effectively handle the treatment of special populations and chronic patients thanks to coverage of these challenges.
  • Digital/Print
    edited by Leonardo Bolognese, Roberto Ferrari.
    Digital : Oxford2005
    Print2005
  • Digital
    Peter Biberthaler, Sebastian Siebenlist, James P. Waddell, editors.
    Springer2019
    This volume focuses on acute trauma to the adult elbow, including fractures, dislocations, tendon ruptures, and vascular and nerve injuries. Each chapter addresses anatomical key features, surgical and conservative therapeutic procedures, postoperative regimes and complication strategies. International elbow experts explore a range of surgical approaches, the usage of modern implants, advances in surgical techniques, and pearls and pitfalls for each trauma entity. Moreover, the authors describe total elbow arthroplasty and radial head replacement in detail, outline current clinical outcomes, and provide recommendations for therapeutic approaches and salvage measures. The book enables the orthopedic surgeon to deal with the entire spectrum of acute simple and complex elbow injuries in adults.
  • Digital
    Hideo Yamanouchi, Solomon L. Moshé, Akihisa Okumura.
    ScienceDirect2018
    Section I. Introduction -- Section II. Pathophysiology -- Section III. Diagnostic Strategy -- Section IV. Subtypes of Acute Encephalopathy -- Section V. Subtypes of Acute Encephalitis -- Section VI. Encephalopathy/Encephalitis With Refractory Epileptic Status: Rima Nabbout -- Section VII. Management of Acute Encephalopathy and Encephalitis.
  • Digital
    edited by Greet van den Berghe.
    Springer2008
  • Digital
    editor, Qin Ning.
    Springer2019
    This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology, state-of–the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the daily management of ACLF. The rationality and strategies for basic research as well as patient management in this book can also be a valuable reference for other fatal and end stage liver diseases than HBV induced ACLF. This volume 1 has 6 chapters and focuses on the definition, research technology, virology, genetics, and immunology.
  • Digital
    Qin Ning, editor.
    Springer2019
  • Digital/Print
    Alexandre Mebazaa, Mihai Gheorghiade, Faiez M. Zannad, and Joseph E. Parrillo (eds.).
    Digital : Springer2008
    Print2008
  • Digital
    Wolfgang Krüger.
    Springer2017
  • Digital
    Wolfgang Krüger and Andrew Ludman.
    Springer2009
  • Digital/Print
    edited by M. Gheorghiade, F. Zannad.
    Digital : Oxford2005
    Print2005
  • Digital
    R.G. Gonzalez, J.A. Hirsch, M.H. Lev, P.W. Schafer, L.H. Schwamm (editors).
    Springer2011
  • Digital
    Jaechan Park, editor.
    Springer2017
    Section 1: Basics -- 1. Pathophysiology of ischemic stroke -- 2. Pathophysiology of moyamoya disease -- 3. Radiological assessment of ischemic stroke -- 4. Pathology of blood clot -- Section 2: Medical Practices -- 5. General management & intensive care of ischemic stroke -- 6. Cardiac evaluation and management after ischemic cerebral stroke -- 7. Intravenous thrombolytic therapy -- 8. Pediatric ischemic stroke -- Section 3: Endovascular Practices -- 9. History and overview -- 10. Clot aspiration technique -- 11. Stent retriever technique -- 12. Intracranial stenting -- 13. Treatment of arterial dissection -- Section 4: Surgical Practices -- 14. Surgical embolectomy -- 15. Bypass surgery -- 16. Decompressive hemicraniectomy.
  • Digital
    volume editors, Xiaoqiang Ding, Mitchell H. Rosner, Claudio Ronco.
    Karger2018
  • Digital
    volume editors, Xiaoqiang Ding, Claudio Ronco.
    Karger2016
    Acute kidney injury epidemiology : from recognition to intervention / Wang, Y., Fang, Y., Teng, J., Ding, X. -- Acute kidney injury prevention / Chopra, T.A., Brooks, C.H., Okusa, M.D. -- Renal recovery after acute kidney injury / Macedo, E., Mehta, R.L. -- Pathophysiology of septic acute kidney injury / Mårtensson, J., Bellomo, R. -- Biomarkers for diagnosis, prognosis and intervention in acute kidney injury / Fuhrman, D.Y., Kellum, J.A. -- The acute kidney injury to chronic kidney disease transition : a potential opportunity to improve care in acute kidney injury / Palant, C., Amdur, R., Chawla, L.S. -- Electronic data systems and acute kidney injury / Cheungpasitporn, W., Kashani, K. -- Fluid management in acute kidney injury / Chuang, C.-L. -- Multidimensional approach to adequacy of renal replacement therapy in acute kidney injury / Villa, G., Ricci, Z., Romagnoli, S., Ronco, C. -- Timing of renal replacement therapy in acute kidney injury / Ostermann, M., Wald, R., Bagshaw, S.M. -- Pediatric continuous renal replacement therapy / Ricci, Z., Goldstein, S.L. -- Management of cardiac surgery-associated acute kidney injury / Ding, X., Xu, J., Jiang, W., Fang, Y., Teng, J.
  • Digital
  • Digital
  • Digital
    Lynn M. Schnapp, Carol Feghali-Bostwick, editors.
    Springer2017
    Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies. ​
  • Digital
    edited by David Sprigings, John Chambers.
    Wiley2018
    "Acute Medicine offers an accessible and concise guide to the practical management of all acute medical problems likely to be encountered in the emergency department, ambulatory care centre, acute medical unit or on the wards. Reflecting the maturation of acute medicine as a separate specialty, the book is divided into common presentations, specific problems and procedures. New to the fifth edition is a chapter on bed-side ultrasonography; throughout, emphasis is placed on patient safety, and the use of flow diagrams, tables and figures ensures that key information is quickly accessible. Thoroughly revised by experts in the subject, and updated to reflect current approaches to diagnosis and management, Acute Medicine is an excellent companion for the trainee as well as an aide-mm̌oire for the more experienced physician"--Provided by publisher.
  • Digital
    edited by Stephen Haydock, Consultant Physician, Tanuton and Somerset NHS Foundation Trust, UK, Duncan Whitehead, Consultant Nephrologist and Physician, Tanuton and Somerset NHS Foundation Trust, UK, Zoë Fritz, Consultant Acute Physician, Cambridge University Hospitals NHS Foundation Trust and Wellcome Trust Research Fellow in Bioethics at the Universities of Warwick and Cambridge, UK.
    Cambridge2015
  • Digital
    edited by Dariusz Dudek.
    Oxford2008
  • Digital
    Gino M.M.J. Kerkhoffs, Elvire Servien, editors.
    Springer2014
  • Digital/Print
    Lalitha Nagarajan, editor.
    Digital : Springer2010
    Print2010
  • Digital
    edited by Paolo Fortina, Eric Londin, Jason Y. Park, Larry J. Kricka.
    Springer2017
    This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival. The chapters in this book cover topics such as: cytochemical staining, single-cell mass cytometry of AML and Leukemia stem/progenitor cells, microsphere-based assessment of DNA methylation for AML prognosis, a zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation, and the isolation of biologically active exosomes from plasma of patients with cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Acute Myeloid Leukemia: Methods and Protocols is a valuable resource for scientists and researchers to further their studies and advancements in the field of AML.
  • Digital
    Heleen M. Oudemans-van Straaten, Lui G. Forni, A.B. Johan Groenveld, Sean M. Bagshaw, Michael Joannidis, editors.
    Springer2015
    This practical guide provides the reader with answers to important clinically relevant questions regarding the evaluation and management of acute kidney injury (AKI). All aspects of critical care nephrology are covered, from pathophysiology and diagnosis to prevention and treatment. The questions considered relate to a wide range of issues, such as: How do I diagnose AKI? How can I protect the kidney in clinical practice? How do I manage patients with AKI? When should I initiate and how do I perform renal replacement therapy (RTT)? Which type of RTT is most appropriate for my patient? Should I give specific nutrients? In addition to providing practical guidelines and treatment algorithms, the book includes calculators for continuous RRT and anticoagulant dosing. The authors are internationally renowned experts in the fields of Intensive Care Medicine and Nephrology, and all contributions are written in a clear and concise style and have been peer reviewed. Acute Nephrology for the Critical Care Physician will serve as a very useful source for intensivists, internists, anesthesiologists, and nephrologists involved in the management and treatment of critically ill patients at risk of or affected by AKI.
  • Digital
    Denson G. Fujikawa, editor.
    Springer2010
  • Digital
    Thomas Sejersen, Ching H. Wang, editors.
    Springer2014
    This book provides recommendations for evaluation and therapy in the area of acute pediatric neurology; these are presented didactically with frequent use of illustrations and algorithms. Chapters in the first part of the book discuss presenting symptoms of acute neurological conditions. The second part of the book covers major areas of acute pediatric neurology and each of these chapters has three key elements: description of presenting symptoms; recommended assessments; and recommended interventions. Acute Pediatric Neurology provides an accessible, clinically focused guide to assist physicians in the emergency ward or intensive care unit in decisions on diagnosis and therapeutic interventions in all major acute pediatric neurological diseases.
  • Digital
    Oussama Abla, Francesco Lo Coco, Miguel A. Sanz, editors.
    Springer2018
    History of APL -- Molecular Targets of Treatment in APL -- The Leukemic Stem Cell -- The Molecular Genetics of APL -- APL Coagulopathy -- Early Death in APL -- Prognostic Factors in APL -- First-line therapy for APL: Chemotherapy-based approach -- First-line Therapy: ATRA-ATO/Reduced Chemotherapy Approach -- Cure of APL without Chemotherapy -- Minimal Residual Disease in APL -- Treatment of refractory and relapsed APL -- Hematopoietic Stem Cell Transplantation in APL -- APL in Children -- Management of APL in the Elderly -- Special Situations in APL -- APL in Developing Countries: A Chemotherapy-Based Approach -- APL in Developing Countries: ATO based Approach -- Therapy-Related APL -- Rare Acute Leukemia Variants involving Retinoic Acid Receptor Genes -- Management of Treatment-Related Complications in APL.
  • Print
    edited by Augustine M.K. Choi.
    Status: Not Checked Out
    Definitions and clinical risk factors / Moss, Thompson -- Epidemiology of acute lung injury : a public health perspective / Rubenfeld -- Radiographic findings of the acute respiratory distress syndrome / Goodman, Quiñones -- Pulmonary pathology of ARDS : diffuse alveolar damage / Kobzik, Sholl -- Pathogenesis of acute lung injury : experimental studies / Baron, Perrella -- Pathogenesis of acute lung injury : clinical studies / Creagh-Brown, Evans -- Apoptosis in the pathogenesis and resolution of the acute lung injury / Matute-Bello, Martin -- Pathogenesis of ventilator-induced lung injury / Valenza, Frank, Imai, Slutsky -- Sepsis in the acute respiratory distress syndrome : treatment implications / Wheeler, Rice -- Transfusion related acute lung injury / Looney, Gajic -- Mechanisms of fibroproliferation in acute lung injury / Morse, Feghali-Bostwick -- Current approaches and recent advances in the genetic epidemiology of acute lung injury/acute respiratory distress syndrome / Gong, Christiani -- Gene expression profiling and biomarkers in ARDS / Howrylak, Choi -- Resolution of alveolar edema : mechanisms and relaltionship to clinical acute lung injury / Ware, Matthay -- Lung vascular dysfunction and repair in acute lung injury : role of the endothelial cytoskeleton / Lang, Chiang, Garcia -- Surfactant therapy in the acute respiratory distress syndrome / Spragg, Lewis -- Prone position in ARDS / Anzueto, Gattinoni -- Mechanical ventilation in the acute respiratory distress syndrome / Brower, Brochard -- Fluid therapy and hemodynamic monitoring in acute lung injury / Calfee, Gupta, Matthay -- Pathogenesis of sSepsis and septis-induced acute lung injury / Harris ... [et al.] -- Cell-based therapy for acute lung injury and acute respiratory distress syndrome / Gupta, Lee, Matthay -- Chemokines and cytokines in ARDS / Keane, Kelly, Streiter.
  • Digital
    Davide Chiumello, editor.
    Springer2017
    This book covers all clinical aspects of acute respiratory distress syndrome (ARDS), from definition to treatment, focusing on the more recent recommendations and evidence-based medicine. The addressed topics are the various ventilation strategies, the impact of prone positioning, the use of partial and total extracorporeal support, the value of vasodilators, the weaning from mechanical ventilation, the pharmacological interventions, noninvasive ventilation, and the strategies using anti-inflammatory agents and stem cells. Furthermore, different related topics are also discussed, such as lung imaging, sedation, metabolic support, and hemodynamic instability. A concluding chapter specifically addresses ARDS in children. This up-to-date volume, written by experts in the field, will be of value for all health care practitioners seeking state of the art on the management of patients with this complex syndrome.
  • Digital
    David Bochner.
    Neural plasticity is high during developmental critical periods, then declines by adulthood. Here by acutely disrupting PirB function at different ages, we show that Paired immunoglobulin like receptor B (PirB) actively restricts plasticity both during and after the critical periopd. Chapter 1 introduces ocular dominance (OD) plasticity as a model of circuit and synaptic change, and presents a review of the literature on the study of mechanisms of OD plasticity, critical period timing, and manipulations that can alter plasticity later in life. Chapter 2 presents an overview of the methodological approaches used. PirB function was disrupted with temporal precision via either a conditional PirB allele or by minipump infusion of a soluble PirB ectodomain into mouse visual cortex. Chapter 3 details the effects of disrupting PirB function on plasticity in healthy animals. OD plasticity is enhanced not only during the critical period, but also when PirB function is disrupted in adulthood. The effects of adult deletion can occur even when PirB is only lost in excitatory neurons of the forebrain. Acute blockade of PirB for 10 days after the close of the critical period increases spine density on apical and basolateral dendrites of Layer 5 pyramidal neurons. Chapter 4 presents a proof of concept for therapeutic disruption of PirB function in cases of neurological dysfunction and disease. Long term monocular deprivation (LTMD) during the critical period leads to a lasting loss of vision in the deprived eye and to a decrease in dendritic spine density that does not recover even with subsequent binocular vision. However, acute blockade of PirB following LTMD allows for full recovery of spine density. MeCP2308/y mice, a mouse model of Rett Syndrome (a syndromic autism), were found to have increased MHC Class I expression and a concurrent loss of OD plasticity during the critical period, which can be rescued by acute blockade of PirB. Taken together, these results imply that mechanisms for enhanced structural and functional plasticity are present in adult visual cortex but are actively repressed by PirB. By removing negative regulators such as PirB, we show that it is possible to engage these endogenous mechanisms to facilitate recovery from otherwise irreversible effects of dysfunctional development. Our observations suggest that similar manipulations may be useful in other situations where restoring synaptic plasticity and increasing spine density have therapeutic value.
  • Digital
    Ainaz Sourati, Ahmad Ameri, Mona Malekzadeh.
    Springer2017
    This book provides clear guidance on how to manage a wide range of side effects frequently encountered when treating patients with radiation therapy. For each potential side effect, incidence, mechanism, symptoms, and grading are carefully described. All aspects of management are addressed, drawing on the latest available evidence and highlighting key details of importance in clinical routine. The introduction of new radiation therapy techniques such as 3D conformal radiation therapy, intensity-modulated radiation therapy, and image-guided radiation therapy has reduced normal tissue doses and, accordingly, treatment complications. Nevertheless, a significant percentage of patients still experience acute side effects, in part because the threshold doses for these toxicities are typically lower than those for late effects. Acute toxicities may lead to interruption of treatment and be associated with an increase in late damage. A swift and effective response is therefore essential. This book will enable the reader to provide effective care for each side effect, thereby improving patient compliance with treatment and treatment outcomes.
  • Digital
    Edgar A. Samaniego, David Hasan, editors.
    Springer2019
    This book contains a compilation of the revolution of mechanical thrombectomy (MT) in the treatment of strokes. The initial chapters summarize information about the best medical management of acute ischemic stroke, imaging modalities and patient selection for MT. The book then focuses on the nuances of MT, providing detailed information about the best approaches for anesthesia during MT, access, intra-arterial thrombolysis, recent devices and catheters and technical pitfalls of MT. A specific chapter is dedicated to MT in the venous system. This is followed by a chapter about the most common complications of MT and post-procedural care of these patients. The last chapter covers different aspects of acute stroke care and MT in the developing world. The authors of this book comprise of a multidisciplinary group of world experts in the field and were encouraged to include teaching cases to deliver a book with a practical approach. Acute Stroke Management in the Era of Thrombectomy is intended for all healthcare providers who care for patients with stroke; with special emphasis for the proceduralists who are interested in technical tips to improve outcomes and minimize complications.
  • Digital
    volume editors, Olivier Rabin, Yannis Pitsiladis.
    Karger2017
    Brief introduction to the history of anti-doping / Ljungqvist, A. -- The development of the world anti-doping code / Young, R. -- Is the fight against doping in sport a legal minefield like any other? / Haas, U. -- How will the legal and sport environment influence a future code? / Niggli, O. -- Structure and development of the list of prohibited substances and methods / Kinahan, A.; Budgett, R.; Mazzoni, I. -- Therapeutic use exemptions / Gerrard, D.; Pipe, A. -- Challenges in modern anti-doping analytical science / Ayotte, C.; Miller, J.; Thevis, M. -- Achievements and challenges in anti-doping research / Bowers, L.D.; Bigard, X. -- Gene and cell doping : the new frontier : beyond myth or reality / Neuberger, E.W.I.; Simon, P. -- The athlete biological passport : how to personalize anti-doping testing across an athlete's career? / Robinson, N.; Sottas, P.-E.; Schumacher, Y.O. -- Next generation "omic" approaches in the "fight" against blood doping / Wang, G.; Karanikolou, A. ; Verdouka, I.; Friedmann, T.; Pitsiladis, Y. -- Integration of the forensic dimension into anti-doping strategies / Marclay, F.; Saugy, M. -- How to develop intelligence gathering in efficient and practical anti-doping activities / Holz, M; Robertson, J. -- Education in anti-doping: the art of self-imposed constraints / Loland, S. -- Can we better integrate the role of anti-doping in sports and society? : a psychological approach to contemporary value-based prevention / Petróczi, A. ; Norman, P.; Brueckner, S. -- Sport, society, and anti-doping policy : an ethical overview / Bloodworth, A.J.; McNamee, M. -- A moral foundation for anti-doping : how far have we progressed? where are the limits? / Murray, T.H. -- Conclusion and perspectives / Howman, D.
  • Digital
    volume editor, Manfred Lamprecht.
    Karger2012
    Beta-alanine supplementation in high-intensity exercise / Harris, R.C., Sale, C. -- Arginine and citrulline supplementation in sports and exercise : ergogenic nutrients / Sureda, A., Pons, A. -- Dietary nitrate and O2 consumption during exercise / Jones, A.M., Bailey, S.J., Vanhatalo, A. -- GABA supplementation and growth hormone response / Powers, M. -- Exercise, intestinal barrier dysfunction, and probiotic supplementation / Lamprecht, M., Frauwallner, A. -- Pleuran (glucan from pleurotus ostreatus) : an effective nutritional supplement against upper respiratory tract infections / Majtan, J. -- Bovine colostrum and immune function after exercise / Davison, G. -- Supplementation with mixed fruit and vegetable concentrates in relation to exercise, performance and sport : scientific insight and practical relevance / Lamprecht, M. -- Cherry juice targets antioxidant potential and pain relief / Kuehl, K.S. -- Impact of milk consumption and resistance training on body composition of female athletes -- Josse, A.R., Phillips, S.M. -- Glycerol use in hyperhydration and rehydration : scientific update -- Van Rosendal, S.P., Coombes, J.S. -- Salt and fluid loading : effects on blood volume and exercise performance / Mora-Rodriguez, R., Hamouti, N. -- Milk protein and the restoration of fluid balance after exercise / James, L. -- Chocolate milk : a post-exercise recovery beverage for endurance sports / Pritchett, K., Pritchett, R. -- Role of supplementary l-carnitine in exercise and exercise recovery / Huang, A., Owen, K. -- Supplements and inadvertent doping : how big is the risk to athletes? / Judkins, C., Prock, P.
  • Digital
    Janis Kent.
    Wiley2017
    Accessible Routes -- Site Elements -- Vertical Access -- Architectural Elements -- Restrooms & Bathing Facilities -- Other Elements -- A Word or Two on Existing Projects -- Innovative Ideas on Access World-Wide.
  • Digital
    Michael A. Kahn, J. Michael Hall.
    Wiley2018
    The extraoral and intraoral soft tissue head and neck screening examination -- Soft tissue head and neck pathology description and documentation -- Common oral soft tissue lesions -- Differential diagnosis of common oral soft tissue lesions -- Guidelines for observation and/or referral of patients lesions -- The art and science of biopsy and cytology -- Sample patient histories and discussion.
  • Digital
    NCBI Bookshelf2017
  • Print
    Allan H. Ropper, Martin A. Samuels.
    Status: Not Checked Out
    Approach to the patient with neurologic disease -- Special techniques for neurologic diagnosis -- Motor paralysis -- Abnormalities of movement and posture caused by disease of the basal ganglia -- Incoordination and other disorders of cerebellar function -- Tremor, myoclonus, focal dystonias, and tics -- Disorders of stance and gait -- Pain -- Other somatic sensation -- Headache and other craniofacial pains -- Pain in the back, neck, and extremities -- Disorders of smell and taste -- Disturbances of vision -- Disorders of ocular movement and pupillary function -- Deafness, dizziness, and disorders of equilibrium -- Epilepsy and other seizure disorders -- Coma and related disorders of consciousness -- Faintness and syncope -- Sleep and its abnormalities -- Delirium and other acute confusional states -- Dementia and the amnesic (korsakoff) syndorme with comments on the neurology of intelligence and memory -- Neurologic disorders caused by lesions in specific parts of the cerebrum -- Disorders of speech and language -- Fatigue, asthenia, anxiety, and depressive reactions -- The limbic lobes and the neurology of emotion -- Disorders of the autonomic nervous system, respiration, and swallowing -- The hypothalamus and neuroendocrine disorders -- Normal development and deviations in development of the nervous system -- The neurology of aging -- Disturbances of cerebrospinal fluid and its circulation, including hydrocephalus, pseudotumor cerebri, and low-pressure syndromes -- Intracranial neoplasms and paraneoplastic disorders -- Infections of the nervous system (bacterial, fungal, spirochetal, parasitic) and sarcoidosis -- Viral infections of the nervous system chronic meningitis, and prion diseases -- Cerebrovascular diseases -- Craniocerebral trauma -- Multiple sclerosis and allied demyelinating diseases -- Inherited metabolic diseases of the nervous system -- Developmental diseases of the nervous system -- Degenerative diseases of the nervous system -- The acquired metabolic disorders of the nervous system caused by nutritional deficiency -- Alcohol and alcoholism -- Disorders of the nervous sytem caused by drugs, toxins, and other chemical agents -- Diseases of the spinal cord -- Electrophysiologic and laboratory aids in the diagnosis of neuromuscular disease -- Diseases of the peripheral nerves -- Diseases of the cranial nerves -- Principles of clinical myology: diagnosis and classification of disease of muscle and neuromuscular junction -- The infectious and inflammatory myopathies -- The muscular dystrophies -- The metabolic and toxic myopathies -- The congenital neuromuscular disorders -- Myasthenia gravis and related disorders of the neuromuscular junction -- Ion channel disorders: the periodic paralyses and hereditary nondystrophic myotonias (channelopathies) -- Disorders of muscle characterized by cramp, spasm, pain, and localized masses -- The anxiety neuroses, hysteria, and personality disorders -- Depression and bipolar disease -- The schizophrenias and paranoid states.
  • Digital
    Allan H. Ropper, Martin A. Samuels, Joshua P. Klein.
    AccessMedicine2014
    Ch. 1. Approach to the patient with neurologic disease -- Ch. 2. Imaging, electrophysiologic, and laboratory techniques for neurologic diagnosis -- Ch. 3. Motor paralysis -- Ch. 5. Ataxia and disorders of cerebellar function -- Ch. 6. Tremor, myoclonus, focal dystonias, and tics -- Ch. 7. Disorders of stance and gait -- Ch. 10. Headache and other craniofacial pains -- Ch. 11. Pain i n the back, neck, and extreities -- Ch. 12. Disorders of smell and taste -- Ch. 13. Disturbances of vision -- Ch. 14. Disorders of ocular movement and pupillary function -- Ch. 15. Deafness, dizziness, and disorders of equilibrium -- Ch. 16. Epilepsy and other seizure disorders -- Ch. 17. Coma and related disorders of consciousness -- Ch. 18. Faintness and syncope -- Ch. 19. Sleep and its abnormalities -- Ch. 20. Delirium and other acute confusional states.
  • Digital
    Allan H. Ropper, Martin A. Samuels, Joshua P. Klein, Sashank Prasad.
    AccessMedicine2019
    "The definitive text on the full spectrum of neurology presented in full color and better than ever! Long considered the field's gold-standard text, Adams and Victor's Principles of Neurology provides the very latest treatment and management strategies needed to confidently handle both common and rare neurologic conditions. Presented in full color, this classic resource meets the needs of the seasoned professional or the aspiring clinician, and has been hailed as the most detailed, thorough, and authoritative text on the subject. Reviewers have favorably compared the book's consistent, single voice to consulting with an experienced senior colleague. The latest scientific research is included in just the right amount of detail to serve as a clinical reference or a starting point for additional learning. The text is logically divided into six sections: The Clinical Method of Neurology; Cardinal Manifestations of Neurologic Disease; Growth and Development of the Nervous System in the Neurology of Aging; Major Categories of Neurologic Diseases; Diseases of the Spinal Cord, Peripheral Nerve, and Muscle; Psychiatric Disorders"-- Provided by publisher. "The wise application of science, evidence from trials, and the traditional virtues of the neurological history and examination are the main purpose of this edition of Principles of Neurology"-- Provided by publisher.
  • Digital
    Dragos Iliescu.
    Cambridge2017
    This book provides a practical but scientifically grounded step-by-step approach to the adaptation of tests in linguistic and cultural contexts.
  • Digital
    Giovanni Laviola, Simone Macrì, editors.
    Springer2013
    1. The Inductive Agency of Stress: From Perinatal to Adolescent Induction / Trevor Archer and Richard M. Kostrzewa -- Part I. Introductory Concepts -- 2. Making Sense of Stress: An Evolutionary-Developmental Framework / Marco Del Giudice, Bruce J. Ellis, and Elizabeth A. Shirtcliff -- 3. Prenatal and Maternal Psychosocial Stress in Primates: Adaptive Plasticity or Vulnerability to Pathology? / Dario Maestripieri and Amanda C.E. Klimczuk -- Part II. Adaptive and Maladaptive Consequences of Developmental Stress In Humans -- 4. The Everyday Stress Resilience Hypothesis: Unfolding Resilience from a Perspective of Everyday Stress and Coping / Jennifer A. DiCorcia, Akhila V. Sravish, and Ed Tronick -- 5. Ontogeny of Stress Reactivity in the Human Child: Phenotypic Flexibility, Trade-Offs, and Pathology / Mark V. Flinn, Davide Ponzi, Pablo Nepomnaschy, and Robert Noone -- 6. Consequences of Developmental Stress in Humans: Prenatal Stress / Nadine Skoluda and Urs M. Nater -- 7. Consequences of Developmental Stress in Humans: Adversity Experienced During Childhood and Adolescence / Urs M. Nater and Nadine Skoluda -- Part III. Adaptive and Maladaptive Consequences of Developmental Stress in Animal Models -- 8. Behavioural and Neuroendocrine Consequences of Prenatal Stress in Rat / Sara Morley-Fletcher, Jérôme Mairesse, and Stefania Maccari -- 9. Developmental Consequences of Prenatal Administration of Glucocorticoids in Rodents and Primates / Jonas Hauser -- 10. Early Developmental Trajectories of Brain Development: New Directions in the Search for Early Determinants of Health and Longevity / F. Cirulli and A. Berry -- 11. Adaptive Regulations in Developing Rodents Following Neonatal Challenges / Laurence Coutellier -- 12. Adaptive and Maladaptive Regulations in Response to Environmental Stress in Adolescent Rodents / Simone Macrì and Giovanni Laviola -- 13. Oxidative Stress and Hormetic Responses in the Early Life of Birds / David Costantini.
  • Digital
    Julie Marie Granka.
    Organismic evolution involves both selective and neutral forces, although their relative contributions are often unknown. This thesis proposes novel statistical methods for analyzing genetic data from a variety of organisms, including yeast, Mycobacterium tuberculosis, and humans. The chapters of this thesis provide complimentary perspectives on the relative roles of selection and neutrality, from the molecular to the population level, and present various statistical tools for genetic data analysis. Chapter 2 proposes a maximum-likelihood based method with which to classify and identify interactions, or epistasis, between pairs of genes. Chapter 3 details a study of genetic data from Mycobacterium tuberculosis isolated from human Aboriginal Canadian communities; our analyses suggest that the bacterium spread to these communities via the Canadian fur trade in the 18th and 19th centuries. Chapter 4 discusses the detection of signatures of natural selection in the genomes of 12 diverse African human populations, and proposes novel considerations for identifying biological functions under selection and for comparing signals of selection between populations. Finally, Chapter 5 details the inference of the genetic basis and evolutionary history of light skin pigmentation and short stature in the genetically diverse [not equal to sign] Khomani Bushmen of the Kalahari Desert of South Africa, believed to be one of the world's most ancient human populations. These chapters emphasize that a more complete understanding of the evolutionary history of humans and other organisms requires not only the consideration of neutral and selective processes, but also both phenotypic and genetic information. The statistical methods and approaches presented in the following chapters have the potential to improve inferences of natural selection and demography from genetic data, as well as provide insight into the relative roles of both.
  • Digital
    Olivia Yueh-Wen Liao.
    When developing new drugs, Phase I and II trials are commonly conducted to determine the dose of the new treatment in preparation for the subsequent confirmatory Phase III trial. However, because these early-phase trials usually do not have large enough sample sizes to decide which dosage level or treatment regimen is the best, several of them may arise as candidates for the confirmatory Phase III trial. Conventional fixed sample size designs that carry out all the treatment arms of interest are obviously expensive. Therefore, the pharmaceutical industry is increasingly interested in adaptive designs that can use information acquired during the course of the trial to update certain of the design features. In this thesis we explore several existing designs and discuss their pros and cons. We then propose one that shares the flexibility of Bayesian adaptive designs, while still being able to maintain the frequentist type I error probability. We develop an asymptotic theory for efficient outcome-adaptive randomization schemes and optimal stopping rules. Our approach consists of developing asymptotic lower bounds for the expected sample sizes from the treatment arms and the control arm, and using generalized sequential likelihood ratio procedures to achieve these bounds. These allow us to allocate patients and study resources efficiently by using outcome-adaptive randomization schemes, or by arm suspension/selection if fixed randomization is used. We also derive an adaptive test with a p-value that can be evaluated by Monte Carlo simulation based on an ordering scheme of the sample space. We then show that the approach can also be applied to the closely related problem of multi-stage testing of multiple hypotheses.
  • Digital
    Zoya Farzampour.
    This dissertation studies mechanisms that mediate inhibitory and excitatory synaptic transmission in the healthy brain and in animal models of stroke and epilepsy. Stroke is a major cause of disability yet lacks pharmacotherapies for recovery (Donnan et al., 2008). During the repair phase, spontaneous cortical circuit plasticity and reorganization adjacent to the stroke site (peri-infarct) promote functional recovery (Carmichael, 2006; Dijkhuizen et al., 2001; Murphy and Corbett, 2009; Nudo et al., 1996). Elucidating mechanisms that target these endogenous brain repair processes could lead to new therapeutics with a broad treatment window. Inhibiting the post stroke increase in tonic (extrasynaptic) GABA signaling during the repair phase was reported to enhance functional recovery in mice, suggesting that GABA plays an important function in modulating brain repair (Clarkson et al., 2010). While tonic GABA appears to suppress brain repair after stroke, the role of phasic (synaptic) GABA during the repair phase is unknown. In Chapter 2, we report a post-synaptic increase in phasic GABA signaling within the peri-infarct cortex that is specific to layer 5 pyramidal neurons; we measured increased numbers of alpha-1 receptor subunit containing GABAergic synapses detected using array tomography, and an associated increased efficacy of spontaneous and miniature inhibitory post-synaptic currents in pyramidal neurons. In contrast to the reported effects of tonic inhibition, enhancing phasic GABA signaling in the recovery phase using zolpidem, an alpha-1 subunit positive allosteric modulator (Crestani et al., 2000), improved behavioral recovery. These data identify a novel role for phasic GABA signaling in brain repair, indicate zolpidem's potential to improve recovery, and underscore the necessity to distinguish the role of tonic and phasic inhibition in stroke recovery. Temporal lobe epilepsy (TLE) is the most common form of adult seizure disorder and is often associated with drug refractory epilepsy (Wiebe, 2000). GABAARs are thought to play a key role in the pathophysiology of many types of epilepsy, including TLE, and are the target site of benzodiazepines, commonly used as antiepileptic medications (Noebels et al., 2012a; Gonzalez and Brooks-Kayal, 2011). Previous studies have shown dentate granule cells display an increased pharmacological response to the central benzodiazepine receptor (CBR) antagonist flumazenil (FLZ) after status epilepticus (SE) in an animal model of temporal lobe epilepsy. It has been previously reported that in slices taken from pilocarpine-induced epileptic rats, hippocampal dentate granule cells demonstrate a FLZ induced reduction in mIPSC half width. This is in contrast to control animals, where FLZ application has no effect on dentate granule cell mIPSC kinetics. The mechanism(s) by which FLZ reduces mIPSC half width in SE tissue is not known, but one hypothesis is that an endogenous compound active at the CBR may be upregulated after SE. However, in Chapter 3 I performed preliminary experiments in animals with SE and did not find a consistent reduction in mIPSC parameters after SE previously reported (Leroy et al., 2004). My results demonstrate that FLZ is not acting as a pure negative allosteric modulator (NAM), but instead may act occasionally as a NAM and predominantly as a positive allosteric modulator (PAM) or that NAMs are expressed after seizures and actually weaken IPSCs. These experiments suggest that a small subset of dentate granule cells respond to FLZ with varying response profiles. Synaptic transmission requires a continuous supply of neurotransmitter for release. Although most types of neurons use direct reuptake to recycle released neurotransmitters, evidence indicates that glutamatergic synapses rely predominantly on astrocytes for generation and recycling of glutamate (Hertz, 1979). Although biochemical studies suggest that excitatory neurons are metabolically coupled with astrocytes to generate the glutamate necessary to maintain glutamatergic neurotransmission, direct electrophysiological evidence is lacking. In fact, a requirement for the cycle has only been demonstrated during epileptiform activity, a disease setting in which glutamate release is greatly increased (Bacci et al., 2002; Otsuki et al., 2005; Tani et al., 2010). The large distance between cell bodies and axon terminals limits the contribution of somatic sources to the pool of glutamate available for synaptic release and predicts that glutamine-glutamate cycle is synaptically localized. In Chapter 4, we investigated neurotransmitter release from isolated nerve terminals in brain slices by transecting hippocampal Schaffer collaterals and cortical layer I axons. Stimulating with alternating periods of high frequency (20 Hz) and rest (0.2 Hz), we identified an activity-dependent reduction in synaptic efficacy that correlated with reduced glutamate release. This was enhanced by inhibition of astrocytic glutamine synthetase and reversed or prevented by exogenous glutamine. Importantly, this activity dependence was also revealed with an in vivo derived natural stimulus both at network and cellular levels. These data provide direct electrophysiological evidence that an astrocyte-dependent glutamate-glutamine cycle is required to maintain active neurotransmission at excitatory terminals.
  • Digital
    edited by John C. Moore, Peter C. de Ruiter, Kevin S. McCann, Volkmar Wolters.
    Cambridge2018
    Introduction -- Part I. Food Webs: Complexity and Stability -- 1. Food webs versus interaction networks: principles, pitfalls, and persepectives -- 2. What kind of interaction- type diversity matters for community stability -- 3. Symmetry, asymmetry, and beyond: the crucial role of interaction strength in the complexity-stability debate -- 4. Ecologically effective population sizes and functional extinction of species in ecosystems -- 5. Merging antagonistic and mutualistic bipartite webs: a first step to integrate interaction diversity into network approaches -- 6. Toward multiplex ecological networks: accounting for multiple interaction types to understand community structure and dynamics -- 7. Unpacking resilience in food webs: an emergent property or a sum of the parts? -- Part II. Food Webs: From Traits to Ecosystem Functioning -- 8. Integrating food-web and trait-based ecology to investigate biomass-trait feedbacks -- 9. Including the life cycle in food webs -- 10. Importance of trait-related flexibility for food-web dynamics and the maintenance of biodiversity -- 11. Ecological succession investigated through food-web flow networks -- 12. Statistical approaches for inferring and predicting food-web architecture -- 13. Global metawebs of spide predation highlight consequences of land-use change for terrestrial predator-prey networks -- 14. Ecological networks in managed ecosystems: connecting structure to services -- 15. Trait-based and process-oriented modeling in ecological network dynamics -- 16. Empirical methods of identifying and quantifying trophic interactions for constructing soil food-web models -- Part III. Food Webs and Environmental Sustainability -- 17. Integrating species interaction networks and biogeography -- 18. Food-web dynamics when divergent life-history strategies respond to environmental variation differently: a fisheries ecology perspective -- 19. Rare but important: perturbations to uncommon species can have a large impact on the structure of ecological communities -- 20. Food-web simulations: stochastic variability and systems-based conservation -- 21. An individual-based simulation model to link population, community, and metacommunity dynamics -- 22. Structural instability of food webs and food-web models and their implications for management -- 23. Linking ecology and epidemiology: the case of infected resource -- Index.
  • Digital
    Dickon Bevington, Peter Fuggle, Liz Cracknell, Peter Fonagy.
    Oxford Clinical Psychology2017
  • Digital
    David Arnold Purger.
    Myelin sheaths, specialized segments of oligodendrocyte plasma membranes in the central nervous system, facilitate fast, saltatory conduction of action potentials down axons. Myelination of the central nervous system requires the generation of functionally mature oligodendrocytes from oligodendrocyte precursor cells. Changes to the fine structure of myelin in a neural circuit are expected to affect conduction velocity of action potentials. Recent evidence from humans and animal models suggests that myelination may be sensitive to experiences during development and adulthood, and that varying levels of neuronal activity may underlie these experience-dependent changes in myelin and myelin-forming cells, perhaps selectively instructing myelination of an active neural circuit. In this thesis, I present work using optogenetic stimulation of premotor cortex in awake, behaving mice to demonstrate that neuronal activity elicits a mitogenic response of neural and oligodendrocyte precursor cells, promotes oligodendrogenesis and increases myelination within the deep layers of the premotor cortex and subcortical white matter. Neuronal activity-regulated oligodendrogenesis and myelination is associated with improved motor function of the corresponding limb. Oligodendrogenesis and myelination appear necessary for the observed functional improvement, as epigenetic blockade of oligodendrocyte differentiation and myelin changes prevents the activity-regulated behavioral improvement. A deeper understanding of adaptive myelination may provide insights into diseases involving damage and dysregulation of myelin and myelin-forming cells.
  • Digital
    Kensuke Sekihara, Srikatan S. Nagarajan.
    Springer2008
  • Digital/Print
    Office of Small Business Development.
    Digital : Google Books1981-
    Print1981-
  • Digital
    edited by Nick Heather, Gabriel Segal.
    OSO2016
    The central problem in the study of addiction is to explain why people repeatedly behave in ways they know are bad for them. For much of the previous century and until the present day, the majority of scientific and medical attempts to solve this problem were couched in terms of involuntary behaviour; if people behave in ways they do not want, then this must be because the behaviour is beyond their control and outside the realm of choice. An opposing tradition, which finds current support among scientists and scholars as well as members of the general public, is that so-called addictive behavior reflects an ordinary choice just like any other and that the concept of addiction is a myth. The editors and authors of this book tend to take neither view. There has been an increasing recognition in recent literature on addiction that restricting possible conceptions of it to either of these extreme positions is unhelpful and is retarding progress on understanding the nature of addiction and what could be done about it.This book contains a range of views from philosophy, neuroscience, psychiatry, psychology and the law on what exactly this middle ground between free choice and no choice consists of and what its implications are for theory, practice and policy on addiction. The result amounts to a profound change in our thinking on addiction and how its devastating consequences can be ameliorated. Addiction and Choice is a thought provoking new volume for all those with an interest in this global issue.
  • Digital
    edited by Maria A. Sullivan and Frances R. Levin.
    Oxford Medicine Online2016
    An evidence-based review of diagnostic and treatment strategies for successfully managing alcohol and substance use disorders in older adults. With contributions from leaders in the field of addiction treatment, this volume offers the most current clinical recommendations and describes best practices for implementing effective treatments in this growing patient population.
  • Digital
    edited by John B. Saunders, Katherine M. Conigrave, Noeline C. Latt, David J. Nutt, E. Jane Marshall, Walter Ling, Susumu Higuchi.
    Oxford Medicine Online2016
    1. The nature of addictive disorders / John B. Saunders -- 2. Epidemiology and prevention / Peter Anderson, Katherine M. Conigrave, Louisa Degenhardt, Wayne Hall, and Tim Stockwell -- 3. Pharmacology and pathophysiology / Kazutaka Ikeda, Daisuke Nishizawa, David J. Nutt, and John B. Saunders -- 4. The scope of intervention / Sawitri Assanangkornchai and John B. Saunders -- 5. Establishing the diagnosis / Glenys Dore, Noeline C. Latt, and John B. Saunders -- 6. Acute care / Glenys Dore, Noeline C. Latt, E. Jane Marshall, John B. Saunders, and Peter Thompson -- 7. Ongoing management of substance use disorders / Stephen Jurd and John B. Saunders -- 8. Tobacco / Renee Bittoun, Katherine M. Conigrave, Hisatsugu Miyata, and Nicholas Zwar -- 9. Alcohol / Robert Batey, Katherine M. Conigrave, Colin Drummond, Noeline C. Latt, E. Jane Marshall, David J. Nutt, Richard Saitz, and John B. Saunders -- 10. Cannabis / H. Valerie Curran, Margaret Haney, David J. Nutt, and John B. Saunders -- 11. Opioids / Robert Batey, Katherine M. Conigrave, Noeline C. Latt, David J. Nutt, John B. Saunders, Andrew J. Saxon, and George Woody -- 12. Pain and opioids / James Bell -- 13. Benzodiazepines and the other sedative-hypnotics / Noeline C. Latt, David J. Nutt, and John B. Saunders -- 14. Psychostimulants / Glenys Dore, Walter Ling, and David J. Nutt -- 15. Hallucinogens and dissociative drugs / David J. Nutt and Adam R. Winstock -- 16. Other drugs / Jenny Bearn, Jonathan Brett, Adam Brodie, Katherine M. Conigrave, Shivani Khan, Janie Sheridan, Iain Smith, Catherine Woodstock Striley, David Taylor, and Adam R. Winstock -- 17. Polysubstance use / Jason P. Connor and Gerald F. X. Feeney -- 18. Injecting drug use / Robert Batey, Katherine M. Conigrave, Paul Haber, and John Strang -- 19. Gambling / Henrietta Bowden-Jones, Sanju George, Yasunobu Komoto, David J. Nutt, <i>and Taku Sato</i> -- 20. Gaming / Hideki Nakayama and Hiroshi Sakuma -- 21. Other addictive disorders / Takayuki Harada, Susumu Higuchi, Satoko Mihara, and John B. Saunders -- 22. Psychiatric comorbidity / Glenys Dore, Anne Lingford-Hughes, and John B. Saunders -- 23. Specific clinical situations / Noeline C. Latt, John B. Saunders, and Sue Wilson -- 24. Special populations / Sawitri Assanangkornchai, Tatiana Balachova, Yvonne Bonomo, Katherine M. Conigrave, Ilana B. Crome, Glenys Dore, Bradley Freeburn, Marianne Jauncey, Michael Levy, Corinne Lim, Ross McCormick, and Kim Wolff -- 25. Substance use and specific health care settings / Jonathan Brett, Tim Neumann, Richard Saitz, John B. Saunders, Claudia Spies, and Pierluigi Struzzo -- 26. Legal and ethical issues / Katherine M. Conigrave, Glenys Dore, Emily Finch, Ralph Hingson, Noeline C. Latt, Sally Porter, and John B. Saunders.
  • Digital
    edited by Bankole A. Johnson.
    Springer2011
    This book attempts to "bridge the gap between the explosion of neuroscientific and behavioral knowledge in the past three decades and treatment delivery in clinical practice. As such, it should fulfill the role of a comprehensive textbook that integrates addiction medicine from its scientific underpinnings to the treatment of patients in clinical settings"--Preface, p. vii.
  • Digital
    edited by Andrian Carter, Wayne Hall, Judy Illes.
    ScienceDirect2012
    What is addiction neuroethics and why does it matter? -- Brain Imaging in Addiction -- Molecular Neuroscience and Genetics -- Treating Opioid Dependence with Opioids: Exploring the Ethics -- Addiction Neuroscience and Tobacco Control -- Emerging Neurobiological Treatments of Addiction: Ethical and Public Policy Considerations -- Technical, Ethical and Social Issues in the Bioprediction of Addiction Liability and Treatment Response -- Autonomy, Responsibility and the Oscillation of Preference -- Consent and Coercion in Addiction Treatment -- Toward a Lay Descriptive Account of Identity in Addiction Neuroethics -- The Impact of Changes in Neuroscience and Research Ethics on the Intellectual History of Addiction Research -- The Diction of Addiction at the Intersection of Law and Neuroscience -- Social Epistemology: Communicating Neuroscience -- Population Approaches to Alcohol, Tobacco and Drugs: Effectiveness, Ethics and Interplay with Addiction Neuroscience -- Legal Regulation of Addictive Substances and Addiction -- Investment and Vested Interests in Neuroscience Research of Addiction: Ethical Research Requires More than Informed Consent -- Private and Public Approaches to Addiction Treatment: Evidence and Beliefs.
  • Digital
    John F. Kelly, William L. White, editors.
    Springer2011
    Addiction Recovery Management: Theory, Research, and Practice is the first book on the recovery management approach to addiction treatment and post-treatment support services. Distinctive in combining theory, research, and practice within the same text, this ground-breaking title includes authors who are the major theoreticians, researchers, systems administrators, clinicians and recovery advocates who have developed the model. State-of-the art and the definitive text on the topic, Addiction Recovery Management: Theory, Research, and Practice is mandatory reading for clinicians and all professionals who work with patients in recovery or who are interested in the field.
  • Digital
    edited by Ronald Ross Watson, Sherma Zibadi.
    ScienceDirect2017
  • Digital
  • Digital
    Introduction -- What health providers need to know about food insecurity -- Prepare and screen -- What health providers need to know about federal nutrition programs -- Intervene and advocate -- Additional resources for pediatricians to address food insecurity.
  • Digital
    Marla McDaniel, S. Darius Tandon, Caroline Heller, Gina Adams, Susan J. Popkin.
    This brief offers strategies for service providers in public or assisted housing communities to develop strong home visiting services for highly distressed families battling challenges such as depression, substance abuse, or domestic violence. It also provides information on one strategy in particular--the SCRIPT model--that gives concrete instructions for better serving families' mental health and other needs in home visiting programs. The brief also offers insights into how the model's framework could be adapted to allow local communities to respond to their community's particular needs, challenges, and contexts.
  • Digital
    Nancy E. Adler, David M. Cutler, Jonathan E. Fielding, Sandro Galea, M. Maria Glymour, Howard K. Koh, and David Satcher.
    Despite the powerful effects of social and behavioral factors on health, development, and longevity, US health policy has largely ignored them. The United States spends far more money per capita on medical services than do other nations, while spending less on social services. Residents of nations that have higher ratios of spending on social services to spending on health-care services have better health and live longer. The relative underinvestment in social services helps to explain why US health indicators lag behind those of many countries. The best available evidence suggests that a health policy framework addressing social and behavioral determinants of health would achieve better population health, less inequality, and lower costs than our current policies.
  • Digital
    Richard Saitz, editor.
    Springer2013
    "While there is a wealth of published information on addiction medicine, the psychological aspects of alcohol abuse, and behavioral medicine with regard to addiction, virtually none of the existing resources were written with the primary care provider in mind. Addressing Unhealthy Alcohol Use in Primary Care is a handy reference for primary care clinicians who are confronted by patients with these problems daily, and who wish to successfully address these issues in their practice. Focusing on the literature and science relevant to practicing providers, this book covers the range of interventions appropriate for this setting. Topics include assessment, brief counseling interventions, pharmacotherapy, referrals to both specialty care and Alcoholics Anonymous (and other self-help programs), psychiatric comorbidity and other drug use, and other information specific to the needs of the primary care clinician. The vast majority of people with health risks and consequences related to alcohol use receive little to no attention from healthcare, despite the fact that alcohol is a leading cause of early preventable death. This book is a guide to identifying and addressing unhealthy alcohol use in hopes of improving the lives of patients."--publisher's website
  • Digital
    editors Richard A. Rudick, Robert A. Bermel.
    Future Med2011
    Addressing unmet medical needs in RR-MS / Robert A. Bermel & Richard A. Rudick -- Current guidelines and standard treatments of RR-MS / R. Philip Kinkel & Augusto Miravalle -- Oral agents for the treatment of RR-MS / Douglas R. Jeffery -- Monoclonal antibodies / Jennifer Graves & Emmanuelle L. Waubant -- Other therapeutics in the pipeline and future directions / Yuval Karmon, Bijal K. Mehta & Bianca Weinstock-Guttman.
  • Digital
    edited by Richard O. Snyder, Philippe Moullier.
    Springer2011
    Adeno-associated virus biology / Matthew D. Weitzman and R. Michael Linden -- Design and construction of functional AAV vectors / John T. Gray and Serge Zolotukhin -- AAV capsid structure and cell interactions / Mavis Agbandje-McKenna and Jürgen Kleinschmidt -- Exploring natural diversity of AAV for the design of vectors with novel properties / Guangping Gao, Li Zhong, and Olivier Danos -- Gene therapy in skeletal muscle mediated by adeno-associated virus vectors / Chunping Qiao ... [et al.] -- AAV mediated liver-directed gene therapy / Mark S. Sands -- Recombinant AAV delivery to the central nervous system / Olivier Bockstael ... [et al.] -- Adeno-associated virus mediated gene therapy for retinal degenerative diseases / Knut Steiger ... [et al.] -- Adeno-associated virus vector delivery to the heart / Lawrence T. Bish ... [et al.] -- Evaluation of the fate of rAAV genomes following in vivo administration / K. Reed Clark and Magalie Penaud-Budloo -- Measuring immune responses to recombinant AAV gene transfer / Ashley T. Martino ... [et al.] -- Modificaton and labeling of AAV vector particles / Hildegard Büning ... [et al.] -- AAV mediated gene targeting / Daniel G. Miller -- Preclinical study design for rAAV / Terence R. Flotte, Thomas J. Conlon, and Christian Mueller -- Biodistribution and shedding of AAV vectors / Caroline Le Guiner, Phillipe Moullier, and Valder R. Arruda -- Production and purification of recombinant adeno-associated vectors / Lijun Wang ... [et al.] -- rAAV vector product characterization and stability studies / Richard O. Snyder, Muriel Audit, and Joyce D. Francis -- rAAV human trial experience / Katherine A. High and Patrick Aubourg.
  • Digital
    Paul M. Schneider (ed.).
    Springer2010
  • Digital
    Simone Giacopuzzi, Andrea Zanoni, Giovanni de Manzoni, editors.
    Springer2017
    This book offers up-to-date and comprehensive coverage of the diagnosis and therapy of adenocarcinoma of the esophagogastric junction (EGJ). As is appropriate in the era of multidisciplinary and multimodal treatment, the contributions of all the various specialists involved cooperatively in the treatment of EGJ cancer are thoroughly described. Detailed attention is also paid to the significance of preneoplastic lesions, such as Barrett esophagus. The final part of the book represents a surgical atlas documenting the techniques used in the EGJ region, with superb color images and stepwise description of procedures. Against the background of the rapidly increasing incidence in EGJ cancer, especially evident in Western countries, there is a need for greater uniformity in management strategies, which currently vary significantly across the world. This book provides appropriate guidance that will assist all practitioners involved in the diagnosis and treatment of EGJ cancers, including surgeons, oncologists, and radiotherapists.
  • Digital
    Susan Masino, Detlev Boison, editors.
    Springer2013
    Adenosine and Metabolism--A Brief Historical Note / Bertil B. Fredholm -- Adenosine Metabolism, Adenosine Kinase, and Evolution / Jaoek Park and Radhey S. Gupta -- Adenosine and Energy Metabolism--Relationship to Brain Bioenergetics / Xuesong Chen, Liang Hui and Jonathan D. Geiger -- Adenosine and Autocrine Metabolic Regulation of Neuronal Activity / Masahito Kawamura Jr. and David N. Ruskin -- Physiologic and Metabolic Regulation of Adenosine: Mechanisms / Chris G. Dulla and Susan A. Masino -- The Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the Books / Stephanie zur Nedden, Alexander S. Doney and Bruno G. Frenguelli -- Downstream Pathways of Adenosine / Ana M. Sebastião, Sofia Cristóvão-Ferreira and Joaquim A. Ribeiro -- Astrocytic ATP Release / Dustin J. Hines and Philip G. Haydon -- Role of Striatal A2A Receptor Subpopulations in Neurological Disorders / Sergi Ferré, César Quiroz, Marco Orrú, Xavier Guitart and Seema Gulyani, et al. -- Sleep and Adenosine: Human Studies / Tarja Porkka-Heiskanen -- Adenosine and Other Purinergic Products in Circadian Timing / Christine Muheim and Steven A. Brown -- Adenosine in the Immune System / György Hask, Balázs Koscsó́ and Balázs Csóka -- The Bioenergetic Network of Adenosine in Hibernation, Sleep, and Thermoregulation / Kelly L. Drew and Tulasi R. Jinka -- Adenosine and Stroke / Felicita Pedata, Anna Maria Pugliese, Francesca Corti and Alessia Melani -- The Many Roles of Adenosine in Traumatic Brain Injury / Patrick M. Kochanek, Jonathan D. Verrier, Amy K. Wagner and Edwin K. Jackson -- Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitution After Spinal Cord Injury / Kwaku D. Nantwi -- Adenosine and Pain / Jana Sawynok -- Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson's Disease / Annalisa Pinna, Nicola Simola, Lucia Frau and Micaela Morelli -- Adenosine Receptors and Alzheimer's Disease / David Blum, Ursula Sandau, Cyril Laurent, Vânia Batalha and Antoine Leboucher, et al. -- Adenosine Receptors in Huntington's Disease / David Blum, Alberto Martire, Sylvie Burnouf, Bernard Sablonnière and Pierre Krystkowiak, et al. -- Adenosine and Multiple Sclerosis / Maria Victoria Sánchez-Gómez, Estibaliz González-Fernández, Rogelio O. Arellano and Carlos Matute -- Adenosinergic Perspectives on Schizophrenia: Opportunity for an Integrative Synthesis / Benjamin K. Yee, Philipp Singer and Detlev Boison -- The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation / John D. Salamone, Merce Correa, Patrick A. Randall, Eric J. Nunes and Marta Pardo, et al. -- Adenosine and Autism: Physiological Symptoms and Metabolic Opportunities / Julia Svedova, Inge-Marie Eigsti and Susan A. Masino -- Stress, Brain Adenosine Signaling, and Fatigue-Related Behavioral Processes / Traci N. Plumb, Sarah R. Sterlace, Kelly A. Cavanaugh and Thomas R. Minor -- Disruption of Adenosine Homeostasis in Epilepsy and Therapeutic Adenosine Augmentation / Detlev Boison -- Ketogenic Diet and Epilepsy: The Role of Adenosine / Jong M. Rho, Beth Zupec-Kania and Susan A. Masino -- Silk: A Biocompatible and Biodegradable Biopolymer for Therapeutic Adenosine Delivery / Eleanor M. Pritchard, Detlev Boison and David L. Kaplan -- Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy / Zsolt Kovács and Arpád Dobolyi.
  • Digital/Print
    Charles E. Samuel, editor.
    Digital : Springer2012
    Print2012
    ADAR proteins : structure and catalytic mechanism / Rena A. Goodman, Mark R. Macbeth and Peter A. Beal -- ADAR proteins : double-stranded RNA and Z-DNA binding domains / Pierre Barraud and Frédéric H.-T. Allain -- Editing of neurotransmitter receptor and ion channel RNAs in the nervous system / Jennifer L. Hood and Ronald B. Emeson -- Modulation of microRNA expression and function by ADARs / Bjorn-Erik Wulff and Kazuko Nishikura -- Nuclear editing of mRNA 3'-UTRs / Ling-Ling Chen and Gordon G. Carmichael -- Control of ADAR1 editing of hepatitis delta virus RNAs / John L. Casey -- Bioinformatic approaches for identification of A-to-I editing sites / Eli Eisenberg -- ADARs : viruses and innate immunity / Charles E. Samuel -- Role of ADARs in mouse development / Carl R. Walkley, Brian Liddicoat and Jochen C. Hartner -- Regulation and functions of ADAR in Drosophila / Simona Paro, Xianghua Li, Mary A. O'Connell and Liam P. Keegan.
  • Digital
    Constance N. Wilson, S. Jamal Mustafa, editors ; contributors, M.P. Abbracchio ... [et al.].
    Springer2009
  • Digital
    edited by David Blum, Luísa V. Lopes.
    ScienceDirect2017
    Adenosine receptor biology in the central nervous system / Michael Freissmuth and Karl-Norbert Klotz -- Adenosine signaling throughout development / Stefania Zappettini and Christophe Bernard -- Influence of adenosine on synaptic excitability / Detlev Boison, Raquel B. Dias, Traci Plumb, Sofia Cristóvão-Ferreira and Ana M. Sebastião -- Regulation of synaptic transmission by adenosine at the neuromuscular junction / Paula Pousinha and Joaquim A. Ribeiro -- Gene regulation of adenosine A₂a receptors in the central nervous system -- Sleep, adenosine, and neurodegeneration / Theresa E. Bjorness and Robert W. Greene -- National vs glial cell contribution to adenosine A₂a receptor-induced neurodegeneration / Antonella Ferrante, Maria T. Tebano, Alberto Martire, Maria R. Domenici and Patrizia Popoli -- Adenosine and oxygen/glucose deprivation in the brain / Felicita Pedata, Ilaria Dettori, Irene Fusco, Elisabetta Coppi, Anna M. Pugliese and Alessia Melani -- Adenosine receptors and memory disorders / Alexandre De Mendonca, David Blum and Jonathan D. Geiger -- Control of motor function by adenosine A₂a receptors in Parkinson's and Huntington's disease / Annalisa Pinna, Jadwiga Wardas, Maria R. Domenici, Patrizia Popoli, Giovanni Cossu and Micaela Morelli -- Adenosine receptors oligomers in Parkinson's disease / Víctor Fernández-Dueñas and Francisco Ciruela -- Adenosine control of striatal function / Sergi Ferré.
  • Digital
    Micaela Morelli, Nicola Simola, Jadwiga Wardas, editors.
    Springer2015
  • Digital
    edited by Miguel Chillón, Assumpció Bosch.
    Springer2014
    Biophysical methods to monitor structural aspects of the adenovirus infectous cycle / Rosa Menéndez-Conejero ... [et al.] -- Proteome analysis of adenovirus using mass spectrometry / Sara Bergström Lind, Konstantin A. Artemenko, and Ulf Pettersson -- Capsid modification strategies for detargeting adenoviral vectors / Alan L. Parker ... [et al.] -- Use of dodecahedron "VLPs" as an alternative to the whole adenovirus / Pascal Fender -- Study of adenovirus and CAR axonal transport in primary neurons / Charleine Zussy and Sara Salinas -- The use of chromatin immunoprecipitation (hIP) to study the binding of viral proteins to the adenovirus genome in vivo / Yueting Zheng and Patrick Hearing -- DNA microarray to analyze adenovirus-host interactions / Stefania Piersanti, Enrico Tagliafico, and Isabella Saggio -- Determination of the transforming activities of adenovirus oncogenes / Thomas Speiseder, Michael Nevels, and Thomas Dobner -- Oncolytic adenovirus characterization : activity and immune responses / Raul Gil-Hoyos, Juan Miguel-Camacho, and Ramon Alemany -- The analysis of innate immune response to adenovirus using antibody arrays / Nelson C. Di Paolo and Dmitry M. Shayakhmetov -- Engineering adenovirus genome by bacterial artificil chromosome (BAC) technology / Zsolt Ruzsics, Frederic Lemnitzer, and Christian Thirion -- Construction, production, and purification of recombinant adenovirus vectors / Susana Miravet ... [et al.] -- Sealable production of adenovirus vectors / Ana Carina Silva ... [et al.] -- Canine adenovirus downstream processing protocol / Meritxell Puig ... [et al.] -- Production of high-capacity adenovirus vectors / Florian Kreppel -- Production of chimeric adenovirus / Marta Miralles ... [et al.]
  • Digital
    Helena M. Tabery.
    Springer2012
    pt. 1. Adenovirus epithelial keratitis -- pt. 2. Thygeson's superficial punctate keratitis.
  • Digital
    Berger, Stephen A.
    ProQuest Ebook Central2018
    Adenovirus infection: Global Status is one in a series of GIDEON ebooks which explore all individual infectious diseases, drugs, vaccines, outbreaks, surveys and pathogens in every country of the world. Data are based on the GIDEON web application (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing exhaustive search of the medical literature. The ebook includes: 1. Descriptive epidemiology 2. Clinical features 3. Distribution map 4. Images 5. Global status and status in every relevant country 6. References.
  • Digital
    Mark L. Wolraich, MD, FAAP, Joseph F. Hagan Jr, MD, FAAP.
    AAP ebooks2019
    Parents will find the latest recommendations for the treatment and care of children with ADHD in the fully revised and updated edition of this award-winning guide.
  • Digital
    Leonard F. Koziol, Deborah Ely Budding, Dana Chidekel.
    Springer2013
    Neuroscience, Neuropsychology, and Attention-Deficit Hyperactivity Disorder: ADHD as a Model of Brain-Behavior Relationships -- ADHD, Attention, and DSM Diagnosis: History and Context -- ADHD and Neuropsychological Nomenclature -- Diagnostic Systems and Etiological Models -- Neuropsychological Models of Attention and ADHD -- Broad-Based Neuropsychological Test Batteries and ADHD -- Preliminary Answers to the Question -- Dimensional Approaches for Evaluating Disorders: Research Domain Criteria -- The Neocortex, Regional Functional Specialization, and Cognitive Networks -- Large-Scale Brain Networks and Functional Connectivity -- The Ontogeny of Functional Brain Networks -- Large-Scale Brain Network Disturbances in ADHD -- The Selection Problem -- The Basal Ganglia -- The Basal Ganglia and Intention Programs -- The Basal Ganglia: Focused Attention and Learning Through Integrative Networks -- Reward Circuitry and the Basal Ganglia -- The Cerebellum -- The Modular Organization of the Cerebellum -- The Development of Motor Skills, Executive Functions, and a Relationship to ADHD: A Preliminary Review -- Revisiting Neuropsychological Testing and the Paradox of ADHD -- Neural Network Dynamics: How Large-Scale Brain Networks Interact -- Concluding Remarks.
  • Digital
    Craig B.H. Surman, editor.
    Springer2013
    ADHD in Adults: A Practical Guide to Evaluation and Management is the product of a unique collaboration of international specialists. This volume offers easy-to-read guidance, and includes checklists, rating scales and treatment planning tools. It was designed for a broad audience of caregivers working in diverse settings, including psychiatrists, social workers, primary care physicians, nurse specialists and psychologists. The authors are highly acclaimed clinicians, investigators and educators. They offer step-by-step guidance for implementation of best practices, drawing from clinical research and their experience treating thousands of patients. They cover diagnosis, treatment planning, and state-of-the-art application of pharmacology, psychotherapy, skill-building, family system and environmental interventions - for both simple and complex cases. The scales and worksheets in this Guide were developed to efficiently facilitate assessment and management. The Editor is an international leader in the field from the Clinical and Research Program in Adult ADHD at Massachusetts General Hospital (MGH) and Harvard Medical School, which has made pioneering and highly cited contributions to the understanding of ADHD. This Guide is a definitive, indispensable resource for all health providers who wish to optimize their approach to adult patients with ADHD.
  • Print
    George J. DuPaul, Thomas J. Power, Arthur D. Anastopoulos, Robert Reid.
    Status: Not Checked Out
    "Attention-deficit/hyperactivity sisorder (ADHD) is one of the most common behavior disorders of childhood. Mental health and school practitioners are frequently faced with the challenge of assessing children and adolescents who might have ADHD. The ADHD Rating Scale-5 is widely used by medical, mental health, and educational practitioners for a variety of activities including screening, diagnostic assessment, and evaluation of treatment outcome"--Provided by publisher.
  • Digital
    Scott A. Davis, editor.
    Springer2016
    Part I. What is known about adherence behavior -- 1. Impact of Non-Adherence in Dermatology -- 2. Models of Adherence -- 3. Impact of demographic and treatment-related factors -- 4. Non-attendance, predictors and interventions -- Part II. Methods of measuring adherence -- 5. Using Retrospective Databases to Study Adherence -- 6. Measuring Adherence in Clinical Trials -- 7. How providers can assess their patients' adherence in clinical settings -- Part III. Adherence in specific diseases -- 8. Topical application and variability of the de facto applied dose: technical aspects -- 9. Adherence in Acne -- 10. Psoriasis and adherence to therapy: individual, treatment-related and general factors -- 11. Adherence in atopic dermatitis -- 12. Adherence in Other Dermatologic Conditions -- Part IV. Strategies to improve adherence -- 13. Optimizing the Physician-Patient Relationship and Educating the Patient about Adherence -- 14. Choosing the treatment the patient is most likely to use -- 15. Dealing with forgetfulness -- 16. Building Motivation and Self-Efficacy.
  • Digital
    Emilio Sacchetti, Antonio Vita, Alberto Siracusano, Wolfgang Fleischhacker.
    Springer2014
    Poor adherence to therapy is one of the main obstacles to treatment effectiveness in schizophrenia. It is the main determinant of relapse, hospitalization, symptom persistence, and poor psychosocial functioning and outcome. Adherence to treatment is affected by various factors related to the disease characteristics, to the patient him- or herself, to the treatment, and to the therapeutic relationship. Some of these factors are modifiable, and both pharmacological and non-pharmacological strategies have been developed for this purpose.This book addresses the different aspects of adherence to treatment in schizophrenia and related disorders in a systematic but easy-to-use manual format. Chapters focus on a full range of issues, including pharmacological and non-pharmacological strategies to enhance adherence and continuity of care, relevant psychological factors, the importance of the patient-doctor relationship, and the need for an alliance with other care-givers. Adherence to Antipsychotics in Schizophrenia will be an invaluable asset for all who are involved in the care of patients with schizophrenia.
  • Digital
    Michael A. Rapoff.
    Springer2010
    Definitions of adherence, types of adherence, problems, and adherence rates -- Consequences of nonadherence and correlates of adherence -- Adherence theories: review, critique, and clinical implications -- Measurement issues: assessing adherence and disease and health outcomes -- Strategies for improving adherence to pediatric medical regimens -- Review of adherence intervention studies and top ten ways to advance research on adherence to pediatric medical regimens.
  • Digital
    Tony Harris, editor.
    Springer2012
    Introduction to adherens junctions: from molecular mechanisms to tissue development and disease -- How AJs evolved -- Evolution of the cadherin-catenin complex -- How cadherins and catenins interact to assemble AJs -- Three-dimensional structure of the cadherin-catenin complex -- Biophysics of cadherin adhesion -- Adherens junction assembly -- How AJs interface with other cellular machinery -- Cytoskeleton and classical cadherin adhesions -- Immunoglobulin superfamily receptors and adherens junctions -- Signaling from the adherens junction -- Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling -- How AJs affect cell behaviour and multicellular development -- Adherens junctions during cell migration -- Adherens junctions and cadherins in Drosophilia development -- Adherens junctions in C. elegans embryonic morphogenesis -- Cadherin function during xenopus gastrulation -- Adherens junctions in mammalian development, homeostasis and disease: lessons from mice -- How AJs affect tissue homeostasis and disease -- Adherens junctions and stem cells -- Adherens junctions and cancer -- Adherens junctions and pathogen entry.
  • Digital
    Lauren Marie Popov.
    Staphylococcus aureus is both a transient skin colonizer and a formidable human pathogen, ranking among the leading causes of skin and soft tissue infections as well as severe pneumonia. The secreted bacterial alpha-toxin is essential for S. aureus virulence in these epithelial diseases. To discover host cellular factors required for alpha-toxin cytotoxicity, we conducted a genetic screen using mutagenized haploid human cells. Our screen identified a cytoplasmic member of the adherens junctions, plekstrin-homology domain containing protein 7 (PLEKHA7), as the second most significantly enriched gene after the known alpha-toxin receptor, a disintegrin and metalloprotease 10 (ADAM10). Here we report a new, unexpected role for PLEKHA7 and several components of cellular adherens junctions in controlling susceptibility to S. aureus alpha-toxin. We find that despite being injured by alpha-toxin pore formation, PLEKHA7 knockout cells recover after intoxication. By infecting PLEKHA7−/− mice with methicillin-resistant S. aureus USA300 LAC strain, we demonstrate that this junctional protein controls disease severity in both skin infection and lethal S. aureus pneumonia. Our results suggest that adherens junctions actively control cellular responses to a potent pore-forming bacterial toxin and identify PLEKHA7 as a potential non-essential host target to reduce S. aureus virulence during epithelial infections.
  • Digital
    Tobias Langenhan, Torsten Schöenberg, editors.
    Springer2016
    Introduction: history of the adhesion GPCR field / J̲örg Hamann, Alexander G. Petrenko -- Molecular and pharmacological properties of adhesion GPCRs. Classification, nomenclature, and structural aspects of adhesion GPCRs / Arunkumar Krishnan, Saskia Nijmeijer, Chris de Graaf, Helgi B. Schi̲th -- 7TM domain structure of adhesion GPCRs / Chris de Graaf, Saskia Nijmeijer, Steffen Wolf, Oliver P. Ernst -- Understanding the structural basis of adhesion GPCR functions / Demet Araç, Norbert Sträter, Elena Seiradake -- Control of adhesion GPCR function through proteolytic processing / Matthias Nieberler, Robert J. Kittel, Alexander G. Petrenko, Hsi-Hsien Lin [and others] -- Tethered agonism: a common activation mechanism of adhesion GPCRs / Ines Liebscher, Torsten Sch̲öneberg -- Versatile signaling activity of adhesion GPCRs / Ayush Kishore, Randy A. Hall -- Adhesion GPCR-related protein networks / Barbara Knapp, Uwe Wolfrum -- The relevance of genomic signatures at adhesion GPCR loci in humans / Peter Kovacs, Torsten Sch̲öneberg -- Adhesion GPCRs as pharmakotargets in organ function and development. Adhesion GPCRs as a putative class of metabotropic mechanosensors / Nicole Scholz, Kelly R. Monk, Robert J. Kittel, Tobias Langenhan -- Adhesion GPCRs govern polarity of epithelia and cell migration / David Strutt, Ralf Schnabel, Franziska Fiedler, Simone Pr̲mel -- Adhesion GPCRs as novel actors in neural and glial cell functions: from synaptogenesis to myelination / Séverine M. Sigoillot, Kelly R. Monk, Xianhua Piao, Fekrije Selimi, Breanne L. Harty -- Control of skeletal muscle cell growth and size through adhesion GPCRs / James P. White -- Adhesion GPCR function in pulmonary development and disease / Marie-Gabrielle Ludwig, Klaus Seuwen, James P. Bridges -- Adhesion GPCRs as modulators of immune cell function / J̲örg Hamann, Cheng-Chih Hsiao, Chang Sup Lee, Kodi S. Ravichandran, Hsi-Hsien Lin -- Heart development, angiogenesis, and blood-brain barrier function is modulated by adhesion GPCRs / Gentian Musa, Felix B. Engel, Colin Niaudet -- Adhesion GPCRs in tumorigenesis / Gabriela Aust, Dan Zhu, Erwin G. Van Meir, Lei Xu.
  • Digital/Print
    edited by Simon Yona, Martin Stacey.
    Digital : Springer2010
    Print2010
    The adhesion GPCRs : gene repertoire, phylogeny, and evolution / Helgi B. Schith, Karl J.V. Nordstrom, and Robert Fredriksson -- Cadherins : developmental roles and future challenges / Caroline J. Formstone -- Latrophilin signalling in tissue polarity and morphogenesis / Tobias Langenhan and Andreas P. Russ -- GPS proteolytic cleavage of adhesion-GPCRs / Hsi-Hsien Lin ... [et al.] -- The latrophilins : "split-personality" receptors / John-Paul Silva and Yuri A. Ushkaryov -- Studies on the very large G protein-coupled-receptor : from initial discovery to determining its role in sensorineural deafness in higher animals / D. Randy McMillan and Perrin C. White -- Adhesion-GPCRs in the CNS / Natalie Strokes and Xianhua Piao -- GPR56 interacts with extracellular matrix and regulates cancer progression / Lei Xu -- Adhesion-GPCRs in tumorigenesis / Gabriela Aust -- Immunity and adhesion-GPCRs / Simon Yona, Hsi-Hsien Lin, and Martin Stacey -- CD97 in leukocyte trafficking / Jorg Hamann ... [et al.] -- The role of CD97 in regulating adaptive T-cell responses / Ian Spendlove and Ruhcha Sutavani -- F4/80 : the macrophage specific adhesion-GPCR and its role in immunoregulation / Hsi-Hsien Lin ... [et al.] -- Signal transduction mediated through adhesion-GPCRs / Norikazu Mizuno and Hiroshi Itoh -- Emerging roles of brain specific angiogenesis inhibitor 1 / Daeho Park and Kodi S. Ravichandran -- Adhesion-GPCRs in the male reproductive tract / Ben Davies and Christiane Kirchhoff.
  • Digital
    edited by Amanda S. Coutts.
    Springer2013
  • Digital
    Yury A. Rovensky.
    Springer2011
    Extracellular matrix -- Cytoskeleton -- Pseudopodia and adhesion structures -- Adhesive interactions of tissue cells with the extracellular matrix -- Cell migration -- Cell responses to chemical heterogeneity of substrata: adhesive islets or paths -- Topographic cell responses -- Intercellular adhesive interactions.
  • Digital
    edited by Ofer Reizes, Nathan A. Berger.
    Springer2017
    Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associated with obesity, including diabetes, cardiovascular disease and cancer, this volume, which discusses most of the major adipocytokines independently and collectively and their roles in normal and pathologic processes, should be useful to all individuals seeking a deeper understanding of these processes. Moreover, it provides a valuable complement to the series on Energy Balance and Cancer, in which each volume is focused on a specific aspect of this process, which now constitutes an expanding problem as the obesity pandemic continues and more of the population reaches the age where cancer is most prevalent. This volume should provide a valuable resource to all clinicians and scientists engaged in caring for susceptible patients and in exploring the relation between energy balance and cancer as well as an important platform to providing the background for research development.
  • Digital
    edited by Jeffrey M. Gimble, Bruce A. Bunnell.
    Springer2011
    Isolation and culture of rhesus adipose-derived stem cells -- Isolation of human adipose-derived stem cells from lipoaspirates -- Isolation of murine adipose-derived stem cells -- In vitro adult rat adipose tissue-derived stromal cell isolation and differentiation -- In vitro adult canine adipose tissue-derived stromal cell growth characteristics -- Adipogenic differentiation of adult equine mesenchymal stromal cells -- Isolation and culture of porcine adipose tissue-derived somatic stem cells -- Automated isolation and processing of adipose-derived stem and regenerative cells -- Methods for the purification and characterization of human adipose-derived stem cells -- Characterization of human adipose-derived stem cells using flow cytometry -- Evaluation of cellular and humoral immune responses to allogeneic adipose-derived stem/stromal cells -- Adipose-derived stromal cells: Cytokine expression and immune cell contaminants -- Gel-based and gel-free proteomic technologies -- Adipogenic differentiation of adipose-derived stem cells -- Three-dimensional culture systems to induce chondrogenesis of adipose-derived stem cells -- Neural differentiation of human adipose tissue-derived stem cells -- Osteogenic differentiation strategies for adipose-derived mesenchymal stem cells -- Generation of adipose stromal cell-derived hepatic cells -- Adipose stem cell differentiation into smooth muscle cells -- Endothelial and cardiac regeneration from adipose tissues -- Epithelial differentiation of human adipose-derived stem cells -- Screening for epigenetic target genes that enhance reprogramming using lentiviral-delivered shRNA -- Adipogenic differentiation of human adipose-derived stem cells on 3D silk scaffolds -- A first approach for the production of human adipose tissue-derived stromal cells for therapeutic use -- Viral transduction of adipose-derived stem cells -- Use of adipose-derived stem cells in high-throughput screening to identify modulators of lipogenesis -- Preservation protocols for human adipose tissue-derived adult stem cells -- Soft tissue reconstruction -- Methods for analyzing microRNA expression and function during osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells -- The generation and the manipulation of human multipotent adipose-derived stem cells -- Cell sheet technology for tissue engineering: The self-assembly approach using adipose-derived stromal cells -- Differentiation of adipose-derived stem cells for tendon repair -- Adipose-derived stem cells for skin regeneration -- Adipose-derived stem cells for periodontal tissue regeneration.
  • Digital
    edited by Bruce A. Bunnell, Jeffrey M. Gimble.
    Springer2018
  • Digital
    Yves-Gérard Illouz, Aris Sterodimas, editors.
    Springer2011
    Cellular and Molecular Aspects of Adipose Tissue -- Isolation of Stem Cells from Human Adipose Tissue: Technique, Problems, and Pearls -- Principles of Liposuction -- Clinical Applications of Liposuction -- Principles of Autologous Fat Transplantation -- Clinical Applications of Autologous Fat Transplantation -- Adipose Stem Cells: From Liposuction to Adipose Tissue Engineering -- Storage of Adipose Stem Cells -- Engineered Scaffolds and Matrices: Tailored Biomaterials for Adipose Stem Cell Engineering -- Fundamentals and Principles of Biomolecules in Adipose Stem Cell Engineering -- Gene Therapy Used for Adipose Stem Cell Engineering -- Stem Cells from Human Adipose Tissue: A New Tool for Pharmacological Studies and for Clinical Applications -- Role of Adipose Stem Cells Therapy in Obesity -- Stem Cell Based Cardioregeneration and Adipose Tissue -- Adipose Stem Cell Engineering: Characterization and Current Application in Neurological Tissue Repair -- Adipose Stem Cell Engineering: Clinical Applications in Plastic and Reconstructive Surgery -- Orthopedic Use of Adipose-Derived Stem Cells -- Adipose-Derived Stem Cells: Characterization and Application in Urology -- Adipose Stem Cell Engineering: Characterization and Current Application in Otolaryngology -- Adipose Stem Cell Technologies for Tissue Regeneration in Dentistry -- Adipose Stem Cells, Tissue Engineering, and Solid Organ Transplantation and Regeneration -- Industrial Approaches to Adipose Stem Cells Engineering -- Future Research in Adipose Stem Cell Engineering -- Conclusions and Future Directions.
  • Digital
    Giamila Fantuzzi, Theodore Mazzone, editors.
    Springer2014
    The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.
  • Digital
    Mikhail G. Kolonin, editor.
    Springer2013
    Preface: Obesity, Adipose Tissue and Cancer Progression -- Metabolic Perturbations Associated with Adipose Tissue Dysfunction and the Obesity-Cancer Link -- Increased Adiposity and Colorectal Cancer -- Adiposity and Diabetes in Breast and Prostate Cancer -- Increased Adipocity and Endometrial Cancer Risk -- Adipokines: Soluble Factors from Adipose Tissue Implicated in Cancer -- Animal Models to Study the Interplay between Cancer and Obesity -- Unraveling the local influence of tumor-surrounding adipose tissue on tumor progression: cellular and molecular actors involved -- Trafficking of Cells from Adipose Tissue to Tumor Microenvironment -- The Impact of Obesity Intervention on Cancer: Clinical Perspectives -- Index.
  • Digital
    Michael E. Symonds, editor.
    Springer2012
    1. Adipocyte Precursors: Developmental Origins, Self-Renewal, and Plasticity / Christian Dani and Nathalie Billon -- 2. Adipocyte Differentiation / José María Moreno-Navarrete and José Manuel Fernández-Real -- 3. Brown Adipose Tissue / Martin Klingenspor and Tobias Fromme -- 4. White Adipose Tissue / Stephane Gesta and C. Ronald Kahn -- 5. Sex Differences in Body Fat Distribution / Alain Veilleux and André Tchernof -- 6. Macrophages and Inflammation / Elise Dalmas, Joan Tordjman, Michèle Guerre-Millo, and Karine Clément -- 7. Adipocyte Growth and Factors Influencing Adipocyte Life Cycle / Srujana Rayalam and Clifton A. Baile -- 8. The Evolution of Mammalian Adipose Tissue / Caroline M. Pond -- 9. Dietary Determinants of Fat Mass and Body Composition / María A. Zulet, María J. Moreno-Aliaga, and J. Alfredo Martínez -- 10. The Genetic Determinants of Common Obesity-Susceptibility / Ruth J.F. Loos -- 11. Early Origins of Obesity and Developmental Regulation of Adiposity / Shalini Ojha and Helen Budge.
  • Digital
    volume editors, Claire Levy-Marchal, Luc Pénicaud.
    Karger2010
    Human lipodystrophies : genetic and acquired diseases of adipose tissue / Capeau, J. ... [et al.] -- The emergence of adipocytes / Laharrague, P.; Casteilla, L. -- Adipose tissue and the reproductive axis : biological aspects / Hausman, G.J.; Barb, C.R -- Unraveling the obesity and breast cancer links : a role for cancer-associated adipocytes? / Dirat, B. ... [et al.] -- Early determinants of obesity / Ong, K -- Metabolic syndrome in childhood : causes and effects / Weiss, R. -- Pathophysiology of insulin resistance in small for gestational age subjects : a role for adipose tissue? / Beltrand, J.; Meas, T.; Levy-Marchal, C. -- The neural feedback loop between the brain and adipose tissues / Pénicaud, L.
  • Digital
    edited by Kaiping Yang.
    Springer2008
  • Digital/Print
    edited by Monica Castiglione and Martine J. Piccart.
    Digital : Springer2009
    Print2009
  • Digital
    editors, Leonard A. Levin, Siv F.E. Nilsson, James Ver Hoeve, Samuel M. Wu ; managing editors, Paul L. Kaufman, Albert Alm.
    ClinicalKey2011
    Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F.E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts. You can also access the complete contents online at www.expertconsult.com. Deepen your grasp of the physiological principles that underlie visual acuity, color vision, ocular circulation, the extraocular muscle, and much more.
  • Digital
  • Print
    Henry Marsh.
    Status: Not Checked Out
    Traces the author's post-retirement work as a surgeon and teacher in such remote areas as Nepal and Ukraine, illuminating the challenges of working in difficult regions and finding purposeful work after a career.
  • Print
    David Tucker ... [et al.].
    AIR basics -- Application settings -- Application windows -- Screens -- HTML content -- PDF support -- Clipboard support -- Drag and drop support -- File system integration -- Embedded SQL database programming -- Encrypted local store -- Application and window native menus -- Taskbar and dock integration -- File types -- Service monitor framework -- Application updates -- AIR application distribution with the broswer API.
  • Digital
    Janet E. McDonagh, Rachel S. Tattersall, editors.
    Springer2019
    This concise guide takes a practical approach to adolescent and young adult (AYA) rheumatology, aiming to cover the needs of any healthcare professional dealing with young people aged 10-24 years. Each chapter contains key management points for readers to readily access disease-specific management as well as highlighting specific AYA issues which differ from pediatric and adult practice. The coverage is comprehensive but concise and designed to act as a primary reference tool for subjects across the field of rheumatology. The book is designed for pediatric/adult rheumatologists, primary care physicians, nurses, allied health professionals and other professionals to understand each topic covered and to take a practical approach to to delivering developmentally appropriate rheumatology health care.
  • Digital
    Lyle J. Micheli, Laura Purcell, editors.
    Springer2018
    This reader-friendly book takes a practical approach to caring for the adolescent athlete. Logically organized by joint, experts in sports medicine address both chronic and acute injuries in addition to congenital conditions.
  • Digital
    [edited by] Sarah Dauchy, Darius Razavi ; [préface, Jacqueline Godet].
    Springer2010
  • Digital
    Lisa Wright and Stan Kutcher.
    Atypon2016
    Adolescent brain development is a fascinating, newly developing field that has so much to offer almost anyone interested in learning more. Adolescence has only come to be established as a unique developmental phase in the last few decades or so. We now know that the human brain undergoes dramatic developmental changes in the postnatal period, not only early after birth but also extending all the way into adulthood. These changes are not uniform, in that the brain regions undergoing the most change during adolescence are not the same as the regions that changed most in the early life period, and the processes of change also differ as we age. Some of the most important changes that we see during the adolescent period are: 1) pruning (or removal) of excessive neural connections, 2) increases in white matter, the portion of brain matter that allows different regions to communicate with one another, and 3) thinning of the cortex, which is comprised of the outer layers of brain matter. Compared with other areas of the brain, the frontal and temporal cortices undergo the most protracted changes in their structure, implying that developments in these areas play a large role in providing the foundation for adolescent behavioural changes. In this book, we compare adolescent behavioural changes with ongoing changes in the brain and discuss potential implications for health and educational policy-making.
  • Digital
    edited by David A. Wolfe, Jeff R. Temple.
    ScienceDirect2018
    Adolescent Dating Violence: Theory, Research, and Prevention summarizes the course, risk/protective factors, consequences and treatment/prevention of adolescent dating violence. Dating violence is defined as physical, sexual, psychological, and cyber behavior meant to cause emotional, physical, or social harm to a current or former intimate partner. The book discusses research design and measurement in the field, focuses on the recent influx of longitudinal studies, and examines prevention and intervention initiatives. Divided into five sections, the book begins by reviewing theory on and consequences of dating violence. Section II discusses risk factors and protective factors such as peer influences, substance use, and past exposure to violence in the family of origin. Section III discusses how social and cultural factors can influence teen dating violence, addressing the prevalence of dating violence among different ethnicities and among LGBTQ teens, and the influence of social media. Section IV discusses recent research priorities including gender inequality, measurement, psychological abuse, and the dual nature of dating violence during adolescence. Section V reviews evidence-based practice for treatment and prevention across various age groups and settings.
  • Digital
    guest editors, Martin M. Fisher, Eduardo Lara-Torre.
    eBook Comp Acad2012
    Preface / Martin M. Fisher, Eduardo Lara-Torre -- A comprehensive approach to the spectrum of abnormal pubertal development / Heather Appelbaum, Shilpa Malhotra -- Adolescents, sex, and the media / Victor S. Strasburger -- Breast disorders in the female adolescent / Nirupama K. De Silva -- Excessive uterine bleeding / Hina J. Talib, Susan M. Coupey -- Overview of sexually transmitted infections in adolescents / Fareeda Haamid, Cynthia Holland-Hall -- Contraception for primary care providers / Shon Patrick Rowan, Jean Someshwar, Pamela Murray -- Fertility preservation for adolescent women with cancer / Jonathan F. Fish -- Pregnancy in adolescents / Amanda Y. Black, Nathalie A. Fleming, Ellen S. Rome -- Premenstrual syndrome and dysmenorrhea in adolescents / Lisa M. Allen, Alexandra C. Nevin Lam -- Adolescent polycystic ovary syndrome / Ellen Lancon Connor -- Ovarian cysts in adolescents : medical and surgical management / Yolanda A. Kirkham, Sari Kives -- Human papillomavirus disease in adolescents : management and prevention / Lea E. Widdice.
  • Digital
    Hina J. Talib, editor.
    Springer2018
    "This book offers a comprehensive and clinically relevant survey of adolescent gynecology. Adolescent Gynecology: A Clinical Casebook addresses the many intersecting considerations of gynecologic and reproductive health care for this population using a concise, case-based format. Organized in four sections, the first introduces chapters on adolescent confidentiality, puberty, and well care. Section II covers varied menstrual disorders, while Section III highlights issues in reproductive health care including sexually transmitted infection and adolescent pregnancy. Finally, Section IV addresses special populations of adolescents, including chapters on girls who have sex with girls, girls who are victims of abuse and girls with special health care needs and chronic health conditions. In each section common gynecologic health issues are discussed in the context of these clinical cases, provide the knowledge needed to further improve comprehensive care of adolescent patients.Adolescent Gynecology: A Clinical Casebook is a unique resource that delivers essential clinical information for Adolescent Medicine and Pediatric and Adolescent Gynecology fellowship trainees, as well as for medical students, resident trainees, and primary care practitioners who are the front-line caregivers for adolescent girls"--Provided by publisher.
  • Digital/Print
    Digital : Google Books1991-
    Print1991-
  • Digital/Print
    Digital : Google Books1991-
    Print1991-
  • Digital
    Pamela A. Foelsch, Susanne Schlüter-Müller, Anna E. Odom, Helen T. Arena, Andrés Borzutzky H., Klaus Schmeck.
    Springer2014
    1. Introduction -- 2. Description of the Disorder -- 3. Theoretical Models and Rationale -- 4. Diagnosis and Treatment Indications -- 5. Treatment -- 6. Adolescent Identity Treatment (AIT) Case Illustration -- 7. Efficacy -- 8. Training and Supervision.
  • Digital
    guest editors, Paritosh Kaul, Maria Trent, Krishna K. Upadhya.
    AAP ebooks2019
    AMSTARs: Adolescent Contraception: Basics and Beyond highlights the fundamental aspects of contraception with an overview of contraceptive methods and epidemiology, provides up-to-date guidance on medical eligibility criteria, and reviews critical policy advances supporting contraceptive access.
  • Digital
    Carl G Leukefeld, Thomas P. Gullotta, Michelle Staton-Tindall, editors.
    Springer2009
    1 A Selected Social History of the Stepping-Stone Drugs / Thomas P. Gullotta 1 -- 2 A Biological/Genetic Perspective: The Addicted Brain / Thomas H. Kelly, Alessandra N. Kazura, Karen M. Lommel, Shanna Babalonis, Catherine A. Martin 15 -- 3 Individual Characteristics and Needs Associated with Substance Misuse of Adolescents and Young Adults in Addiction Treatment / Michael L. Dennis, Michelle K. White, Melissa L. Ives 45 -- 4 Adolescent Substance Abuse Treatment: A Review of Evidence-Based Research / Ken C. Winters, Andria M. Botzet, Tamara Fahnhorst, Randy Stinchfield, Rachel Koskey 73 -- 5 Adolescent Outpatient Treatment / Richard Dembo, Randolph D. Muck 97 -- 6 Evidence-Based Family Treatment of Adolescent Substance Abuse and Dependence / Shaun I. Calix, Mark A. Fine 119 -- 7 Residential Treatment of Adolescents with Substance Use Disorders: Evidence-Based Approaches and Best Practice Recommendations / Robert W. Plant, Peter Panzarella 135 -- 8 Primary Prevention in Adolescent Substance Abuse / Martin Bloom, Thomas P. Gullotta 155 -- 9 Religious Involvement and Adolescent Substance Use / Terrence D. Hill, Amy M. Burdette, Michael L. Weiss, Dale D. Chitwood 171 -- 10 School Prevention / Zili Sloboda 191 -- 11 Community Prevention Handbook on Adolescent Substance Abuse Prevention and Treatment: Evidence-Based Practices / Elizabeth J. D'Amico, Matthew Chinman, Stefanie A. Stern, Abraham Wandersman 213 -- Epilogue: The Status of Knowledge Development and the Unknown / Michele Staton-Tindall, Thomas P. Gullotta, William Walton Stoops, Carl G. Leukefeld 251.
  • Digital
    Christopher Woodhouse.
    Wiley2015
    Adolescent and transitional urology : an introduction -- Anatomical and cystic anomalies -- Stones -- Prune-belly syndrome -- Renal function in adolescents -- Structural anomalies and reconstruction of the ureter -- Vesico-ureteric reflux -- The neuropathic bladder and spina bifida -- Lower urinary tract replacement and reconstruction -- Urinary diversion and undiversion -- Other bladder conditions -- Exstrophy and epispadias -- Cloacal exstrophy -- Posterior urethral valves -- Hypospadias -- Scrotal abnormalities -- The overvirilized female -- The undervirilized male -- Adolescent sexuality and counseling -- Neoplastic disease : outcomes in survivors.
  • Digital
    edited by Nicholas W. Gelbar.
    Oxford Clinical Psychology2017
    "Adolescence is a challenging stage for all individuals, especially for those with Autism Spectrum Disorder (ASD). Individuals with ASD face increased social isolation and engage in more challenging behaviors during adolescence. They also experience increased mental health challenges including anxiety and depression, and they are among the least likely of any disability group to attend college, be competitively employed, or live independently. At the same time, adolescents with ASD face a major shift in available services and support as they exit the K-12 educational system. The need to present what is known about this group in order to inform clinicians, researchers, and educators cannot be understated. Adolescents with Autism Spectrum Disorder synthesizes current science on adolescents and young adults with ASD in order to inform mental health practitioners and education professionals who work directly with these individuals. While early childhood interventions for ASD have been extensively developed and tested, research on adolescents and young adults with ASD has lagged behind until recently. This comprehensive handbook can be utilized to train students and professionals in applied mental health roles. The handbook includes three sections: Part I reviews diagnosis and treatment of adolescents with ASD; Part II details how to support their educational needs; and Part III discusses special populations including college students and young women. Chapters highlight recommendations for clinicians and include study questions and additional resources."-- Provided by publisher. "Adolescents with Autism Spectrum Disorder synthesizes current science on adolescents and young adults with ASD in order to inform mental health practitioners and education professionals who work directly with these individuals"-- Provided by publisher.
  • Digital
    editors Mark McClellan and Farzad Mostashari ; authors James Colbert, S. Lawrence Kocot, Robert Brenner, Mark Monterastelli, Joshua Seidman and Ross White.
    Part 1. Introduction-- Physician Practices and Their Critical Role in the Accountable Care Movement -- 1. Identifying and Managing High-Risk Patients -- 2. Developing High Value Referral Networks -- 3. Using Event Notifications -- 4. Engaging Patients -- Part 2. Case Studies in Accountable Care -- Case Studies in Accountable Care -- Appendix A. Sample ACO Annual Operating Budget -- Appendix B. Helpful Links and Resources -- Appendix C. Glossary of Key Terms.
  • Digital
    edited by Paul Chang.
    Springer2018
    Vitamin B3 in health and disease : toward the second century of discovery / Myron K. Jacobson and Elaine L. Jacobson -- Monitoring poly(ADP-Ribosyl)ation in response to DNA damage in live cells using fluorescently tagged macrodomains / Rebecca Smith and Gyula Timinszky -- In vitro techniques for ADP-ribosylated substrate identification / Giovanna Grimaldi, Giuliana Catara, Carmen Valente, and Daniela Corda -- Assessment of intracellular auto-modification levels of ARTD10 using mono-ADP-ribose-specific macrodomains 2 and 3 of murine Artd8 / Mareike Bütepage, Sarah Krieg, Laura Eckei, Jinyu Li, Giulia Rossetti, Patricia Verheugd, and Bernhard Lüscher -- Biochemical and biophysical assays of PAR-WWE domain interactions and production of iso-ADPr for PAR-binding analysis / Zhizhi Wang and Wenqing Xu -- Assays for NAD+-dependent reactions and NAD+ metabolites / Michael B. Schultz, Yuancheng Lu, Nady Braidy, and David A. Sinclair -- Generating protein-linked and protein-free mono-, oligo-, and poly(ADP-ribose) in vitro / Ken Y. Lin, Dan Huang, and W. Lee Kraus -- Methods to study TCDD-inducible poly-ADP-ribose polymerase (TIPARP) mono-ADP-ribosyltransferase activity / David Hutin, Giulia Grimaldi, and Jason Matthews -- Dictyostelium as a model to assess site-specific ADP-ribosylation events / Anna-Lena Kolb, Duen-Wei Hsu, Ana B. A. Wallis, Seiji Ura, Alina Rakhimova, Catherine J. Pears, and Nicholas D. Lakin -- Mono-ADP-ribosylation catalyzed by arginine-specific ADP-ribosyltransferases / Linda A. Stevens and Joel Moss -- Monitoring expression and enzyme activity of ecto-ARTCs / Stephan Menzel, Sahil Adriouch, Peter Bannas, Friedrich Haag, and Friedrich Koch-Nolte -- ADP-ribosyl-acceptor hydrolase activities catalyzed by the ARH family of proteins / Masato Mashimo and Joel Moss -- Mono-ADP-ribosylhydrolase assays / Jeannette Abplanalp, Ann-Katrin Hopp, and Michael O. Hottiger -- Hydrolysis of ADP-ribosylation by macrodomains/ Melanija Posavec Marjanovic, Gytis Jankevicius, and Ivan Ahel -- HPLC-based enzyme assays for sirtuins / Jun Young Hong, Xiaoyu Zhang, and Hening Lin -- Small-molecule screening assay for mono-ADP-ribosyltransferases / Teemu Haikarainen, Sudarshan Murthy, Mirko M. Maksimainen, and Lari Lehtiö -- Simple, sensitive, and generalizable plate assay for screening PARP inhibitors / Ilsa T. Kirby, Rory K. Morgan, and Michael S. Cohen -- Nonlocalized searching of HCD data for fast and sensitive identification of ADP-ribosylated peptides / Thomas Colby, Juan José Bonfiglio, and Ivan Matic -- Quantitative determination of MAR hydrolase residue specificity in vitro by tandem mass spectrometry / Robert Lyle McPherson, Shao-En Ong, and Anthony K. L. Leung -- Detection of ADP-ribosylating bacterial toxins / Chen Chen and Joseph T. Barbieri -- Preparation of recombinant alphaviruses for functional studies of ADP-ribosylation / Rachy Abraham, Robert Lyle McPherson, Easwaran Sreekumar, Anthony K. L. Leung, and Diane E. Griffin -- Monitoring the sensitivity of T cell populations towards NAD+ released during cell preparation / Björn Rissiek, Marco Lukowiak, Friedrich Haag, Tim Magnus, and Friedrich Koch-Nolte -- Identifying target RNAs of PARPs / Florian J. Bock and Paul Chang -- ADPr-peptide synthesis / Hans A. V. Kistemaker, Jim Voorneveld, and Dmitri V. Filippov -- Identifying genomic sites of ADP-ribosylation mediated byspecific nuclear PARP enzymes using click-ChIP / Ryan A. Rogge, Bryan A. Gibson, and W. Lee Kraus -- Methods for using a genetically encoded fluorescent biosensor to monitor nuclear NAD+ / Michael S. Cohen, Melissa L. Stewart, Richard H. Goodman, and Xiaolu A. Cambronne.
  • Digital
    volume editors, Peter McCullough, John A. Kellum, Ravindra L. Mehta, Patrick Murray, Claudio Ronco.
    Karger2013
    Acute Dialysis Quality Initiative (ADQI) / Ronco, C., Kellum, J., Bellomo, R., Mehta, R. -- Implementation of novel biomarkers in the diagnosis, prognosis, and management of acute kidney injury : executive summary from the tenth consensus conference of the Acute Dialysis Quality Initiative (ADQI) / McCullough, P.A., for the Acute Dialysis Quality Initiative (ADQI) Consensus Group -- Diagnosis of acute kidney injury using functional and injury biomarkers : workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference / McCullough, P.A., for the ADQI 10 Workgroup -- Differential diagnosis of AKI in clinical practice by functional and damage biomarkers : workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference / Endre, Z.H., for the ADQI 10 Workgroup -- Use of biomarkers to assess prognosis and guide management of patients with acute kidney injury / Cruz, D.N., for the ADQI 10 Workgroup -- Physiological biomarkers of acute kidney injury : a conceptual approach to improving outcomes / Okusa, M.D., for the ADQI 10 Workgroup -- Pathophysiology of the cardiorenal syndromes : executive summary from the eleventh onsensus conference of the Acute Dialysis Quality Initiative (ADQI) / McCullough, P.A., for the Acute Dialysis Quality Initiative (ADQI) Consensus Group. Pathogenesis of cardiorenal syndrome type 1 in acute decompensated heart failure : workgroup statements from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Haase, M., for the Acute Dialysis Quality Initiative (ADQI) Consensus Group -- Pathophysiology of cardiorenal syndrome type 2 in stable chronic heart failure : workgroup statements from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Cruz, D.N., ; for the Acute Dialysis Quality Initiative (ADQI) Consensus Group -- Cardiorenal syndrome type 3 : pathophysiologic and epidemiologic considerations / Bagshaw, S.M., for the Acute Dialysis Quality Initiative 11 Working Group -- Cardiorenal syndrome type 4 : insights on clinical presentation and pathophysiology from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Tumlin, J.A., for the Acute Dialysis Quality Initiative (ADQI) 11 Consensus Group -- Cardiorenal syndrome type 5 : clinical presentation, pathophysiology, and management strategies from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Mehta, R.L., for the Acute Dialysis Quality Initiative (ADQI) 11 Working Group.
  • Digital
    edited by Michael A. Blake, Giles W.L. Boland.
    Springer2009
    Adrenal embryology and pathology -- Adrenocortical dysfunction -- Adrenal medullary dysfunction -- Adrenals in oncology -- Adrenal surgery -- Imaging adrenal dysfunction -- Imaging of pheochromocytomas -- Adrenal imaging using computed tomography: differentiation of adenomas and metastasis -- MRI of the adrenal glands -- Single photon imaging of the adrenal gland -- PET and PET-CT imaging of adrenal lesions -- Adrenal trauma and intervention -- Evolving functional and advanced image analysis techniques for adrenal lesion characterization.
  • Print
    contributors, N.-E. Andén ... [et al.] ; editor, L. Szekeres.
  • Digital
    Gary D. Hammer, Tobias Else, editors.
    Springer2011
    "This first edition of the textbook “Adrenocortical Carcinoma: Basic Sciences and Clinical Concepts” provides a concise compilation of relevant data advancing our current understanding of this rare cancer. Chapters are dedicated to various aspects of both the basic biology and the clinical science relating to adrenocortical carcinoma (ACC). Expert clinicians introduce the reader to current state-of-the-art clinical care of patients with ACC. As a considerable body of knowledge on ACC has accumulated over the last decades, expert scientists have authored additional sections that serve as a reference source for the experienced researcher as well as an introduction for the trainee in the laboratory or clinic. Clinical topics span the epidemiology, diagnosis and therapy of ACC. Scientific topics areas span the pathology and pathophysiology of ACC with a special focus on experimental models of adrenocortical tumors and recent advances in the genetic aspects and signaling pathways in ACC. The content of this book was compiled and edited with the intent of facilitating the translation of knowledge into future diagnostic and therapeutic tools that will ultimately improve patient care."--Publisher's website.
  • Digital
    edited by Anjali Advani and Hillard Lazarus.
    Springer2011
    A perspective on the treatment of acute lymphoblastic leukemia in adults -- Acute lymphocytic leukemia: clinical features and making the diagnosis -- The biology of adult acute lymphoblastic leukemia -- Minimal residual disease in acute lymphoblastic leukemia -- Cytogenetics -- Acute lymphoblastic leukemia: epidemiology -- Prognostic factors in adult acute lymphoblastic leukemia (ALL) -- The generalized care of the patient with acute lymphoblastic leukemia -- Treatment of acute lymphoblastic leukemia in middle-age and older adults -- Pharmacology of acute lymphoblastic leukemia therapy -- Assessment of response to treatment -- T-cell acute lymphoblastic leukemia -- Burkitt lymphoma and leukemia -- Treatment of acute lymphoblastic leukemia in young adults -- Philadelphia chromosome positive acute lymphoblastic leukemia -- Molecular therapies -- Treatment of relapsed acute lymphoblastic leukemia -- Allogeneic stem cell transplantation for acute lymphoblastic leukemia in adults -- Hematopoietic stem cell transplantation in Philadelphia-positive acute lymphoblastic leukemia -- Special challenges: genetic polymorphisms and therapy -- Late consequences of therapy of acute lymphoblastic leukemia -- Immunotherapy for acute lymphoblastic leukemia -- Unique subtypes in acute lymphoblastic leukemia.
  • Digital
    J.J. Sandra Kooij.
    Springer2013
    1. Introduction -- 2. Diagnostic assessment -- 3. Diagnostic instruments -- 4. Treatment -- 5. Treatment: coaching adults with ADHD -- 6. Setup and organization of a specialist department.
  • Digital
    Kursad Turksen, editor.
    Springer2012
  • Digital
    Charles D. Deakin.
    Cambridge2012
  • Digital
    Jason P. Gilleran, Seth A. Alpert, editors.
    Springer2018
    "This text reviews the anatomy and physiology of neuromodulation for treatment of various pathology of the human body, with specific emphasis on sacral neuromodulation for bladder and bowel dysfunction in the adult and pediatric populations. In addition to historical overview of the various methods of neuromodulation, present day applications will be discussed as well as possible future directions for use. Adult and Pediatric Neuromodulation will be of great value to medical professionals who are interested in the use of neuromodulation as a possible therapy option for their patients, particularly when other traditional or medical management options have failed. Each chapter is written by experts in the topic of various modalities of neuromodulation."-- Provided by publisher.
  • Digital/Print
    editors-in-chief, John W. Frymoyer, Sam W. Wiesel ; associate editors, Howard S. An ... [et al.].
    Digital : Ovid2004
  • Digital/Print
    editors, Jay Y. Gillenwater ... [et al.].
    Digital : Ovid2002
  • Digital
    [edited by] David J. Sugarbaker, Raphael Bueno, Mark J. Krasna, Steven J. Mentzer, Lambros Zellos ; with Marcia Williams, Ann Adams.
    AccessSurgery2009
    Care and management of the thoracic surgery patient -- Esophageal and proximal stomach malignancy -- Esophageal motility disorders -- Esophageal reflux disorders -- Benign congenital and traumatic esophageal disorders -- Benign disorders of the upper airways -- Cancer of the upper airways -- Lung cancer -- Benign tumors and conditions of the lung -- Chronic obstructive pulmonary disease -- Lung infections and interstitial lung disease -- Lung transplantation -- Diffuse pleural malignancies and effusions -- Benign pleural conditions -- Chest wall and sternal tumors -- Benign disorders of the chest wall -- Diaphragmatic diseases, benign or malignant -- Mediastinal diseases, benign or malignant -- Robotics.
  • Digital
    editors, David J. Sugarbaker, Raphael Bueno, Yolonda L. Colson, Michael T. Jaklitsch, Mark J. Krasna, Steven J. Mentzer with Marcia Williams, Ann Adams.
    AccessSurgery2015
  • Digital
    Eric L. Chang, Paul D. Brown, Simon S. Lo, Arjun Sahgal, John H. Suh, editors.
    Springer2018
    This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.
  • Digital
    edited by Sara Thorne and Sarah Bowater.
    Oxford Medicine Online2017
    Part 1. Introduction to adult congenital heart disease -- Part 2. Specific lesions -- Part 3. General management issues of adult congenital heart disease.
  • Digital
    Munetaka Masuda, Koichiro Niwa, editors.
    Springer2017
    This book describes the most popular topics concerning adult congenital heart disease (ACHD), especially focusing on indications and re-intervention procedures for some major ACHDs. Thanks to advances in medical and surgical therapy for congenital heart disease over the last half century, many patients who underwent surgical correction reached adulthood. However, as can be seen from the explosive increase in the number of ACHD patients, postoperative residua and sequelae have also become apparent. The purpose of this book is to highlight complicated problems in connection with ACHD, including its present status, as well as methods for its management including medical and surgical treatment. The content primarily focuses on two areas - general information for cardiologists, and information on re-intervention for interventionists and cardiac surgeons -, setting it apart from the majority of books on congenital heart disease.
  • Digital
    Doreen DeFaria Yeh, Ami Bhatt, editors.
    Springer2018
    There is an evident practice gap in education of general adult cardiologists on long-term management of congenital heart disease (CHD). The goal of this book is to help general cardiologists, but also pediatricians and related care providers in the management and diagnosis of adult CHD. Adult Congenital Heart Disease in Clinical Practice provides clear, practical advice on adult CHD for the busy fellow, resident and practicing clinician. It includes training and revision material to assist learning and is formatted in such a way as to provide short, concise content designed for easy recall of salient facts.
  • Digital
    Jan D. Sinnott.
    OSO2014
    1 Introduction: Complex Thought and Adult Intimate Relationships 1 -- 2 The Development of Complex Thought in Adulthood: Some Theories and Mechanisms that Grow with Interpersonal Experience 11 -- 3 The Big Picture: "New Science" Operations and Logics as a Way of Understanding Postformal Thought Operations and Intimate Relationship Processes 23 -- 4 Complex Thought and Emotionally Experienced Close Relationships 51 -- 5 Social, Cultural, and Historical Factors Relate to Cognitive Aspects of Intimate Relationships 67 -- 6 Cognition and Fundamental Complex Relationship Skills: Theory-Limited Nonclinical Literature Related to Cognitive Factors in Intimate Relationships 79 -- 7 Cognition and Fundamental Complex Relationship Skills: Some Preliminary Quantitative and Qualitative Research 97 -- 8 Cognitive Aspects of Close Relationships that Thrive: Practices for Dyads in Intimate Relationships 115 -- 9 Future Research that Includes Culture and History Effects 123.
  • Digital
    Maria T. Codina Leik.
    R2Library2018
  • Digital
    [editors] John J. Callaghan, MD, Lawrence and Marilyn Dorr Chair, Professor, Departments of Orthopaedic Surgery and Biomedical Engineering, University of Iowa, Iowa city, Iowa, Aaron G. Rosenberg, MD, Professor, Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, Harry E. Rubash, MD, Edith M. Ashley Professor, Harvard Medical School, Chief, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, John C. Clohisy, Daniel C. and Betty B. Viehmann Distinguished Professor, Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, Paul E. Beaulé, MD, Professor, Department of Surgery, University of Ottawa, Chief, Division of Orthopedic Surgery, The Ottawa Hospital, Ottawa, Ontario, Craig J. Della Valle, MD, Professor, Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.
    Ovid2016
  • Digital
    Eleftherios Tsiridis, editor.
    Springer2018
    This book is intended to offer a “virtual fellowship” in hip surgery that will give readers the opportunity to join distinguished hip surgeons in the operating room, learning key points and solutions to technical difficulties from the beginning to the end of 100 surgical cases. All of these cases have been carefully selected by renowned orthopaedists who work at the world’s top centers and perform surgery based on evidence. To facilitate quick learning, the cases are presented using a uniform template, guiding the reader from clinical evaluation and preoperative planning, through the decision-making process, to the surgical procedure and the final outcome. At the end of each case, the editor invites the surgeon to answer specific questions in order to further elucidate crucial issues with reference to current evidence. The book is divided into four sections: conservative hip surgery, primary hip arthroplasty, complex hip arthroplasty, and revision arthroplasty. It will be of value across the world to specialist hip surgeons and surgeons in training who are interested in hip surgery.
  • Digital
    edited by Daniele Rigamonti.
  • Digital
    CDC2014
  • Digital
    CDC2014
  • Print
    edited by Clara D. Bloomfield.
    Status: Not Checked Out
  • Digital
    Eric O. Klineberg, editor.
    Springer2017
    Defining Adult Lumbar Scoliosis -- Imaging Adult Lumbar Scoliosis -- Radiographic Parameters for Adult Lumbar Scoliosis -- Patient Reported Outcome Measures Available for Adult Lumbar Scoliosis -- Impact of Depression on the Treatment of Adult Lumbar Scoliosis -- Pre-Operative Clinical Evaluation of Adult Lumbar Scoliosis -- Non-Operative Management of Adult Lumbar Scoliosis -- Surgical Alignment Goals for Adult Lumbar Scoliosis -- Intra-Operative Management of Adult Lumbar Scoliosis -- Biologics for Adult Lumbar Scoliosis -- Assessing the Need for Decompression for Adult Lumbar Scoliosis -- Minimally Invasive Techniques for Adult Lumbar Scoliosis -- Anterior Column Release for Adult Lumbar Scoliosis -- Anterior Column Support Options for Adult Lumbar Scoliosis -- Releases and Osteotomies Used for the Correction of Adult Lumbar Scoliosis -- Distal Fixation for Adult Lumbar Scoliosis: Indications and Techniques -- Diagnosis and Classification of Proximal Junctional Kyphosis and Proximal Junctional Failure -- Prevention Strategies for Proximal Junctional Kyphosis -- Complications Following Surgical Intervention for Adult Lumbar Scoliosis -- Peri-Operative Patient Management of Adult Lumbar Scoliosis -- Patient Reported Outcomes Following the Treatment of Adult Lumbar Scoliosis -- Health Economic Value of the Treatment for Adult Lumbar Scoliosis -- Future Directions for Adult Lumbar Scoliosis.
  • Digital
    edited by Birte Melsen.
    Wiley2012
    Who are the patients -- Chief complaints and problem -- Etiology -- Primary or secondary malocclusions -- Collaboration- Multidisciplinary -- Interdisciplinary -- Treatment planning -- Definition of treatment goal -- Tissue reaction -- Appliance design -- Bonding problem related to adult reconstructed dentitions -- Material related side effects in orthodontics -- Treatment sequence -- Anchorage problems -- Lingual orthdontics -- Patients with periodontal problems -- Patients with prosthodontic problems -- Patients with TMJ problems -- Surgical solution -- Where is the limit? -- Maintenance.
  • Digital/Print
    edited by Irina Klimanskaya, Robert Lanza.
    Digital : ScienceDirect2006
    Print2006
    Ectoderm -- Mesoderm -- Endoderm -- Extraembryonic and perinatal stem cells.
  • Digital
    Donald G. Phinney, editor.
    Springer2011
    Basic Biology of Adult Stem Cells -- Molecular Mechanisms Regulating Adult Stem Cell Self-Renewal -- Maintenance of Adult Stem Cells: Role of the Stem Cell Niche -- The Emerging Role of microRNAs in Adult Stem Cells -- Expression and Function of Pluripotency Genes in Adult Stem Cells -- Adult Stem Cell Plasticity Revisited --Characterization of Adult Stem Cells -- Lineage Tracing of Tissue-Specific Stem Cells In Vivo -- Surrogate Measures of Adult Stem Cell Self-Renewal: The Neural Stem Cell Paradigm -- ABC Transporters, Aldehyde Dehydrogenase, and Adult Stem Cells -- Regulation of Life Span and Immortalization -- Regulation of Life Span in Adult Stem Cells -- The Cancer Stem Cell Paradigm.
  • Digital
    edited by Paolo Di Nardo, Center for Regenerative Medicine, Università di Roma Tor Vergata, Rome, italy, Department of Clinical Sciences and Translational Medicine, Università di Roma Tor Vergata, Rome, italy, Sanjiv Dhingra, Institute of Cardiovascular Sciences, St-Boniface Hospital Albrechtsen Research Centre, Regenerative Medicine Program, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada, Dinender K. Singla, Division of Metabolic and Cardiovascular Sciences, Burnettt School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA.
    Springer2017
    Simple protocol to isolate, characterize, and expand dental pulp stem cells / Federica Di Scipio, Andrea Elio Sprio, Maria Elisabetta Carere, Zhiqian Yang, and Giovanni Nicolao Berta -- Derivation of mesenchymal stem cells from embryonic stem cells : a non-variable and inexhaustive source of adult stem cells / Glen Lester Sequiera, Niketa Sareen, Ejlal Abu El-Rub, and Sanjiv Dhingra -- Compact bone-derived multipotent mesenchymal stromal cells (MSCs) for the Tteatment of Sjogren's-like disease in NOD mice / Ghada Abu Elghanam, Younan Liu, Saeed Khalili, Dongdong Fang, and Simon D. Tran -- Manipulating the proliferative potential of cardiomyocytes by gene transfer / Giulia Prosdocimo and Mauro Giacca -- Assessment of energy metabolic changes in adipose tissue-derived stem cells / Ghazaleh Hajmousa and Martin C. Harmsen -- Isolation and in vitro characterization of epidermal stem cells / Kasper S. Moestrup, Marianne S. Andersen, and Kim B. Jensen -- Endothelial progenitor cells : procedure for cell isolation and applications / Garikipati V.N. Srikanth and Raj Kishore -- Therapeutic application of placental mesenchymal stem cells reprogrammed neurospheres in spinal cord injury of SCID / Vikram Sabapathy, Franklin Jebaraj Herbert, and Sanjay Kumar -- Therapeutic application of human wharton jelly mesenchymal stem cells in skin injury of SCID / Vikram Sabapathy, Balasubramanian Sundaram, and Sanjay Kumar -- Isolation, characterization, and expansion of cancer stem cells / Luke A. Torre-Healy, Artem Berezovsky, and Justin D. Lathia -- Cardiac progenitor cell extraction from human auricles / Paolo Di Nardo and Francesca Pagliari -- Isolation and culture of satellite cells from mouse skeletal muscle / Antonio Musarò and Silvia Carosio -- Isolation of stromal stem cells from adipose tissue / Maria Prat, Francesca Oltolina, Silvia Antonini, and Andrea Zamperone -- Human-induced pluripotent stem cell-derived mesenchymal stem cells as an individual-specific and renewable source of adult stem cells / Glen Lester Sequiera, Sekaran Saravanan, and Sanjiv Dhingra -- Simplified and systematic method to isolate, culture, and characterize multiple types of human dental stem cells from a single tooth / Mohammed Bakkar, Younan Liu, Dongdong Fang, Camille Stegen, Xinyun Su, Murali Ramamoorthi, Li-Chieh Lin, Takako Kawasaki, Nicholas Makhoul, Huan Pham, Yoshinori Sumita, and Simon D. Tran -- Measurement of autophagy by flow cytometry / Silvia Zappavigna, Angela Lombardi, Gabriella Misso, Anna Grimaldi, and Michele Caraglia -- Echocardiography-guided intramyocardial injection method in a murine model / Kay Maeda, Rick Seymour, Marc Ruel, and Erik J. Suuronen -- Noninvasive assessment of cell fate and biology in transplanted mesenchymal stem cells / Federico Franchi and Martin Rodriguez-Porcel -- Methods for long-term storage of murine bone marrow-derived mesenchymal stem cells / Niketa Sareen, Ejlal Abu-El-Rub, Glen Lester Sequiera, Meenal Moudgil, and Sanjiv Dhingra -- Therapeutic application of adult stem cells in the heart / Taylor A. Johnson and Dinender K. Singla -- Patient-derived and intraoperatively formed biomaterial for tissue engineering / Shalmli U. Joshi, Rares O. Barbu, Melissa Carr-Reynolds, Brian Barnes, and Syam P. Nukavarapu -- Three-dimensional printed scaffolds with multipotent mesenchymal stromal cells for rabbit mandibular reconstruction and engineering / Dongdong Fang, Michael Roskies, Mohamed-Nur Abdallah, Mohammed Bakkar, Jack Jordan, Li-Chieh Lin, Faleh Tamimi, and Simon D. Tran -- Optimal environmental stiffness for stem cell mediated ischemic myocardium repair / Honghai Liu, Christian Paul, and Meifeng Xu -- Assessment of MiRNA regulation of endothelial progenitor cell mediated angiogenesis / Darukeshwara Joladarashi and Prasanna Krishnamurthy -- Stem cell exosomes : cell-freetherapy for organ repair / Mohsin Khan and Raj Kishore.
  • Digital
    volume editor, Karl Lenhard Rudolph.
    Karger2015
    Speakers at the symposium -- Stem cells in adult intestine / Feng, J., Sperka, T. -- Molecular mechanisms of muscle stem cell aging / Schwërer, S., Tümpel, S. -- Mechanism of functional alterations in hematopoietic stem cell aging / Morita, Y. -- The microenvironment, aging, and disease / Geiger, H. -- Sestrins in aging and metabolism / Tang, D., Tao S. -- Telomeres and stem cell aging / Felix, D.A. -- DNA damage and checkpoint responses in adult stem cells / Romanov, V., Shukla, A., Ju, Z.
  • Digital
    Toshiki Watanabe, Takuya Fukushima, editors.
    Springer2017
    This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.
  • Digital
    Melvin A. Shiffman, editor.
    Springer2017
    Anatomy -- Ideal Shape of Umbilicus -- Classification -- History -- Position of Umbilicus -- Umbilical Reconstructive Techniques -- Melanoma -- Complications and Outcome.
  • Digital
    Jean-Pierre Michel, Stefania Maggi, editors.
    Springer2019
    After introductory chapters devoted to the safe production and distribution of vaccines, the book addresses the question of adult vaccination in the framework of a life-course approach to vaccination. It presents the proceedings of multidisciplinary expert discussions with an excellent summary of the current state of knowledge on adult vaccination in various diseases, as well as an overview of the professionals involved and the obstacles to achieving greater vaccine uptake, and how these may be addressed. The book systematically discusses the major vaccine-preventable diseases, as well as regulatory issues in vaccine provision, and presents the results of an expert meeting designed to identify the obstacles to vaccination, and solutions for addressing these barriers. It goes on to extend the discussion beyond the traditional boundaries of human health to encompass the “one health” concept. The book is intended for all those with an interest in vaccination, including physicians (from a wide range of disciplines including geriatrics/gerontology, infectious diseases, pediatrics, internal medicine, and other non-organ specialties), other healthcare professionals, pharmacists, representatives of the pharmaceutical industry and regulatory bodies (EMEA, national authorities), policymakers, the media and the general public.
  • Digital
    Peter Lack, Nikola Biller-Andorno, Susanne Brauer, editors.
    Springer2014
    This volume gives an overview on the currently debated ethical issues regarding advance directives from an international perspective. It focuses on a wider understanding of the known and widely accepted concept of patient self-determination for future situations. Although advance directives have been widely discussed since the 1980s, the ethical bases of advance directives still remain a matter of heated debates. The book aims to contribute to these controversial debates by integrating fundamental ethical issues on advance directives with practical matters of their implementation. Cultural, national and professional differences in how advance directives are understood by health care professions and by patients, as well as in laws and regulations, are pinpointed.
  • Digital/Print
    Dongqing Wei, Qin Xu, Tangzhen Zhao, Hao Dai, editors.
    Digital : Springer2015
    Print2015
    This text examines in detail mathematical and physical modeling, computational methods and systems for obtaining and analyzing biological structures, using pioneering research cases as examples. As such, it emphasizes programming and problem-solving skills. It provides information on structure bioinformatics at various levels, with individual chapters covering introductory to advanced aspects, from fundamental methods and guidelines on acquiring and analyzing genomics and proteomics sequences, the structures of protein, DNA and RNA, to the basics of physical simulations and methods for conformation searches. This book will be of immense value to researchers and students in the fields of bioinformatics, computational biology and chemistry. Dr. Dongqing Wei is a Professor at the Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China. His research interest is in the general area of structural bioinformatics.
  • Digital
    [edited by] Linda D. Gillam, Catherine M. Otto.
    ClinicalKey2012
    Transthoracic three dimensional echocardiography / Victor Mor-Avi, Roberto Lang -- Advanced echocardiography approaches: 3D transesophageal assessment of the mitral valve / Jonathan Passeri, Judy Hung -- Two -dimensional and three dimensional echocardiographic evaluation of the right ventricle / Takahiro Shiota -- Transthoracic and transesophageal echocardiography in the catheterization laboratory / Rebecca Hahn and Linda Gillam -- Intracardiac echocardiography for common interventions on structural heart disease / Anna Bortnick and Frank Silvestry -- Strain and strain-rate imaging / Thomas Marwick -- Assessing twist and torsion / Sherif Nagueh -- Echocardiographic tools for cardiac resynchronization therapy / Veronica Lea Dimaano, Kristian Eskesen, and Theadore Abraham -- Contrast perfusion echocardiography / Joan Olson, Feng Xie, and Thomas Porter -- Evaluation of coronary blood flow by echo doppler / Nozomi Watanabe -- Stress testing for structural heart disease / Catherine Otto and David Owens -- Multimodality cardiac imaging -- when is echo not enough? / Nuno Cortez Dias, Ana Almeida, and Fausto Pinto.
  • Digital/Print
    edited by Kelly T. Hughes, Stanley R. Maloy.
    Digital : ScienceDirect2007
    Print2007
    Strain collections and genetic nomenclature / S.R. Maloy ... [et al.] -- Use of antibiotic-resistant transposons for mutagenesis / S.R. Maloy -- In vivo mutagenesis using EZ-Tn5 / J.R. Kirby -- Identification of essential genes in bacteria / D.R. Hillyard ... [et al.] -- Isolation of transposon insertions / S.R. Maloy -- Localized mutagenesis / S.R. Maloy -- Generation of deletions and duplications using transposons as portable regions of homology with emphasis on Mud and Tn10 transposons / K.T. Hughes -- Target-directed proteolysis in vivo / M. Eser ... [et al.] -- Sets of transposon-generated sequence-tagged mutants for structure-function analysis and engineering / B. Traxler ... [et al.] -- Using genomic microarrays to study insertional/transposon mutant libraries / D.N. Baldwin ... [et al.] -- Screening transposon mutant libraries using full-genome oligonucleotide microarrays / K. M. Winterberg ... [et al.] -- Creating recombination-activated genes and sequence-defined mutant libraries using transposons / L. Gallagher ... [et al.] -- Use of operon and gene fusions to study gene regulation in Salmonella / K.T. Hughes ... [et al.] -- Genomic screening for regulatory genes using the T-POP transposon / C. Lee ... [et al.] -- Recombineering: In vivo genetic engineering in E. coli, S. enterica, and beyond / J.A. Sawitzke ... [et al.] -- [lambda]-red genetic engineering in Salmonella enterica serovar Typhimurium / J.E. Karlinsey -- Probing nucleoid structure in bacteria using phage lambda integrase-mediated chromosome rearrangements / N. Garcia-Russell ... [et al.] -- Dissecting nucleic acid-protein interactions using challenge phage / S.R. Maloy ... [et al.] -- Mud-P22 / J.A. Crain ... [et al.] -- Phage metagenomics / V. Casas ... [et al.].
  • Digital
    edited by Grant N. Pierce, Volodymyr I. Mizin and Alexander Omelchenko.
    Springer2013
    "The probability for exposure to damaging radiation, toxic chemicals in the environment and adverse biological agents has increased exponentially today. The more frequent and faster travel that we experience today also escalates the risk of contraction and transmission of potentially deadly infections. This has created a very real and escalating risk for injuries and deaths. This is accentuated in the military and medical staff that is more frequently exposed to radiological, chemical, and biological agents in their normal working environment. Understanding the mechanisms whereby these toxic agents inflict damage to our bodies is essential to prepare us for these challenges. Much of the damage is inflicted through the generation of free radicals and non-radical oxidants which then act through oxidative mechanisms to injury the body. This volume will discuss the damage caused by these radiological, chemical, and biological environmental stressors, the mechanisms through which the damage can occur and the novel strategies that can be used to reduce the injury inflicted by these toxic compounds. Using basic and clinical research approaches, the contents of this book discuss new ideas for the development of bioactive products and environmental approaches to lessen or negate the biological damage inflicted by these noxious compounds."--Publisher's website.
  • Digital
    edited by Ashutosh Tiwari and Anis N. Nordin.
    Wiley2014
    1. Frotiers for bulk nanostructured metals in biomedical applications -- 2. Stimuli-responsive materials used as medical devices in loading and releasing of drugs -- 3. Recent advances with liposomes as drug carriers -- 4. Fabrication, properties of nanoshells with controllable surface charge and its applications -- 5. Chitosan as an advanced healthcare material -- 6. Chitosan and low molecular weight chitosan: biological and biomedical applications -- 7. Anticipating behaviour of advanced materials in healthcare -- 8. Label-free biochips -- 9. Polymer MEMS sensors -- 10. Assembly of polymers/metal nanoparticles and their applications as medical devices -- 11. Combination of molecular imprinting and nanotechnology: beginning of a new horizon -- 12. Prussian blue and analogues: biosensing applications in health care -- 13. Efficiency of biosensors as new generation of analytical approaches at the biochemical diagnostics of diseases -- 14. Nanoparticles: scope in drug delivery -- 14. Smart polypeptide nanocarriers for malignancy therapeutics -- Index.
  • Digital
    edited by Koen Nieman, Oliver Gaemperli, Patrizio Lancellotti, and Sven Plein.
    ScienceDirect2015
    ClinicalKey2015
    "Advances in Cardiac Imaging presents the latest information on heart disease and heart failure, major causes of death among western populations. In addition, the text explores the financial burden to public healthcare trusts and the vast amount of research and funding being channeled into programs not only to prevent such diseases, but also to diagnose them in early stages. This book provides readers with a thorough overview of many advances in cardiac imaging. Chapters include technological developments in cardiac imaging and imaging applications in a clinical setting with regard to detecting various types of heart disease"--Provided by publisher.
  • Print
    editors, Elizabeth Sinz, Kenneth Navarro ; senior managing editor, Erik S. Soderberg ; special contributors, Clifton W. Callaway [and others] ; ACLS Subcommittee 2010-2011, Clifton W. Callaway [and others].
    Status: Not Checked Out
    Course overview -- The systematic approach: the BLS and ACLS surveys -- Effective resuscitation: team dynamics -- Systems of care -- The ACLS cases.
  • Print
    American Heart Association.
    Part 1 Introduction -- Part 2 Systems of Care -- Part 3 Effective High-Performance Team Dynamics -- Part 4 The Systematic Approach -- Part 5 The ACLS Cases: Respiratory arrest case ; Acute coronary syndrome case ; Acute stroke case ; Cardiac arrest: VF/pulseless VT case ; Cardiac arrest: pulseless electrical activity case ; Cardiac arrest: asystole case ; Brachycardia case ; Tachycardia: stable and unstable ; Immediate post-cardiac arrest care case -- Appendix -- Index.
  • Digital
    edited by Toyooki Sonoda, editor.
    Springer2014
    Endoscopic Instruments -- Difficult Polpys: Conventional methods -- Endoscopic Mucosal Resection (EMR) -- Endoscopic Submucosal Dissection (ESD) -- Combined Endoscopic and Laparoscopic Surgery (CELS) -- Colonic Stenting -- Endoscopic Treatment of Perforations of Fistulas.
  • Digital
    Sang W. Lee, Howard M. Ross, David E. Rivadeneira, Scott R. Steele, Daniel L. Feingold, editors.
    Springer2017
    History of Colonoscopy -- Anatomic Basis of Colonoscopy -- Colonoscopy Photo Atlas -- How to Achieve High Rates of Bowel Preparation Adequacy -- Patient comfort during colonoscopy -- VTE Prophylaxis: How to optimize patients on anticoagulation and avoid infectious complications -- Endoscopic Equipment and Instrumentation -- Basic Colonoscopic Techniques to Reach the Cecum -- Basic Colonoscopic Interventions: Cold, Hot Biopsy Techniques, Submucosal Injection, Clip Application, Snare Biopsy -- Current Guidelines for Colonoscopy -- Difficult Colonoscopy: tricks and new techniques for getting to the cecum -- How to recognize, characterize, and manage premalignant and malignant colorectal polyps -- Detection: (CQI) Quality measures and tools for improvement -- Advanced endoscopic imaging: polyps and dysplasia detection -- Endoscopic Mucosal Resection (EMR) -- Endoscopic Mucosal Dissection -- Applications of intra-operative endoscopy -- Combined Endoscopic and Laparoscopic Surgery (CELS) -- Endoluminal Colorectal Stenting -- How to Avoid Complications/Treatment of Endoscopic Complications -- Alternative Colorectal Imaging -- Current Endoluminal Approaches: Transanal Endoscopic Microsurgery, Transanal Minimally Invasive Surgery and Transanal Total Mesorectal Excision.
  • Digital
    edited by Chris D. Geddes and Joseph R. Lakowicz.
    Springerv. 10, 2005.
    pt. A. Small molecule sensing -- pt. B. Macromolecular sensing.
  • Digital
    João Luiz Pinheiro-Franco, Alexander R. Vaccaro, Edward C. Benzel and H. Michael Mayer, editors.
    Springer2016
    In this book, leading international specialists in the field join forces to discuss topics, issues, and approaches that are of key importance in the optimal treatment of lumbar degenerative disk disease. The coverage is wide ranging, from current understanding of physiopathology and genetics and modern imaging techniques through to the diverse minimally invasive, non-fusion, and fusion surgical techniques. Detailed attention is drawn to the most important aspects to be considered when approaching the patient and making treatment decisions. The role of conservative management is appraised, and surgical techniques and their indications are carefully described. Emphasis is placed on the importance of sagittal balance for treatment success. Among the various other subjects covered are psychosocial issues, legal aspects, outcome evaluation, and the relative merits of evidence-based medicine and individual experience. In the concluding section, some of the top specialists from across the world reflect on the lessons that they have learned during lifetimes in spinal surgery. Advanced Concepts in Lumbar Degenerative Disk Disease is intended as the definitive book on this important subject. It will be an instructive and fascinating source of information for all spine surgeons and other spine care providers.
  • Digital
    edited by Mohit Bhandari, Bernd Robioneck ; associate editor, Emil Schemitsch ; managing editor, Sheila Sprague ; with contributions by Volker Alt ... [et al.].
    Thieme MedOne Education2012
    1. Factorial Randomized Trials -- Summary -- Introduction -- Randomized clinical trial design strategies with multiple interventions -- Selecting a factorial randomized design -- Conclusion -- 2. Expertise-based randomized trials -- Summary -- Introduction -- Conventional RCT design -- Expertise-based RCT design -- Challenges of expertise-based RCTs -- Independent assessor -- Balanced and consecutive or random contributions to screening pool -- Perceived equivalence between practices -- Conclusion -- 3. Randomization systems and technology -- Summary -- Introduction -- Methods of patient allocation -- Other considerations -- Conclusion -- 4. Blinding and concealment -- Summary -- Introduction -- Concealment -- Blinding -- Conclusion -- 5. Composite outcome in orthopaedics: understanding the concepts -- Summary -- Introduction -- Rationale for use of a composite outcome -- Limitations of using composite outcomes -- Guidelines for creating a "good" composite outcome -- Reporting and interpreting composite outcomes -- Conclusion -- 6. Adjudication of outcomes-systems and approaches -- Summary -- Introduction -- Importance of adjudication -- Process of adjudication -- Existing methods of adjudication -- Web-based adjudication -- Conclusion -- 7. Subgroup analyses -- Summary -- Introduction -- Subgroup analysis defined -- Design of a subgroup analysis -- Reporting -- Interpretation -- Conclusion -- 8. Trial management-advance concepts and systems -- Summary -- Introduction -- Phases of clinical trials -- Common considerations in conducting a clinical trial -- Trial committees -- The search for funding -- Conclusion 9. Case-control studies -- Summary -- Introduction -- Definition of a case-control study -- Conclusion -- 10. Cohort studies -- Summary -- Introduction -- Cohort studies in the hierarchy of evidence -- Types of cohort study designs -- Methods for reducing confounding and assessing causality -- A checklist to evaluate or improve the strength of evidence -- Conclusion --; 11. Survey Design -- Summary -- Introduction -- Identifying a research question -- Survey development -- Survey design -- Using exiting surveys -- survey validataion -- Pilot testing -- Survey administration -- Ethical considerations -- Financial considerations -- Conclusion -- 12. Qualitative studies -- Summary -- Introduction -- What is qualitative research? -- How is qualitative research done? -- Conclusion -- 13. Economic analysis -- Summary -- Introduction -- Theoretical background -- Conducting health economics studies -- Conclusion -- 14. Literature searches -- Summary -- Introduction -- When to conduct a literature search -- How to conduct a literature search -- Study selection -- Assessing methodological quality of studies -- Data extraction and analysis -- Conclusion -- 15. Summary -- Introduction -- the P value does not assess the magnitude of a treatment effect -- The challenge of comparing results across studies -- Types of effect sizes -- Confidence intervals for effect sizes -- Use of effect size in meta-analysis -- Conclusion -- 16. Fixed effects versus random effects -- Summary -- Introduction -- the data pool: fixed effects versus random effects -- Deciding which model to use -- Conclusion -- 17. Heterogeneity -- Summary -- Introduction -- Heterogeneity defined -- Identifying heterogeneity -- Dealing with heterogeneity -- Conclusion -- 18. Uncovering publicatiion bias -- Summary -- Introduction -- Authors and publication bias -- Detecting and adjusting for publication bias -- Minimizing the effect of publication bias -- A possible solution: trial registers -- Conclusion -- 19. Statiecal pooling - programs and systems -- Summary -- Introduction -- Selectin the appropriate programs and systems: factors to consider --Review of programs and systems -- Types of programs and systems -- Recommendations -- Conclusion -- 20. Meta-analysis of observational studies -- Summary -- Introduction -- The observational data dilemma -- Conclusion -- 21. Meta-regression -- Summary -- Introduction -- Heterogeneity and meta-regression -- Meta-regression mechanics -- Interpreting a meta-regression -- Limitations of meta-regression -- Conclusion -- 22. Preparing a statistical analysis plan -- Summary -- Introduction -- Data management -- Statistical procedures -- Data safety and monitoring board -- Sample size -- Interim analysis -- Reports to investigators -- Sensitivity analysis -- Tables of presentation and publication -- Software -- Reporting guidelines -- General policies -- Privacy considerations -- Apendices -- What is in the literature about SAP? -- Conclusion --; 24. Survival analysis -- Summary -- Introduction -- Documenting time-to-event (survival) data -- the rationale for time-to-event (survival) analysis -- Methods for survival analysis -- Comparing groups -- Practical considerations in the desin of time-to-event studies -- Conclusion -- 25. Interim analyses in randomized trials -- Summary -- Introduction -- Interim analysis defined -- Design of an interim analysis -- Data monitoring committees -- Consequences of stopping early for benefit -- Conclusion -- 26. Conflicts of interest reporting -- Summary -- Introduction -- Legal implications -- Types of conflict of interest -- Who should disclose conflicts of interest? -- When must conflicts of interest be disclosed? -- Guidelines and recommendations for disclosure -- Why must personal financial interests be disclosed? -- Alternatives to disclosure policies -- Conclusion -- 27. Authorship-modern approaches and reporting -- Summary -- Introduction -- Academic stream -- Educational stream -- Industrial stream -- Popular media stream -- Conclusion -- 28. Randomized trials reporting checklists -- Summary -- Introduction -- Consort statement -- Nonpharmacological trials -- NPT extension to consort statement -- CLEAR NPT -- Conclusion -- 29. Observational studies reporting checklists -- Summary -- Introduction -- Checklist for observational studies: the STROBE statement -- Guide to investigators: how to used the STROBE statement -- The STROBE statement: explanations of checklist items -- Conclusion -- 30. Meta-analysis reporting checklists -- Summary -- Introduction -- Meta-analysis reporting checklists -- Conclusion -- Resources and contacts for surgical research -- Summary -- Introduction -- Mentorship -- Graduate programes -- Online courses -- Textbooks and journals -- Courses and workshops -- Contract research organizations -- Conclusion -- Glossary of terms.
  • Digital
    Melvin A. Shiffman, editor.
    Springer2013
    In this book, international experts present up-to-date techniques of otoplasty in which they have extensive personal experience. Both new and modified procedures are described with the aid of a wealth of high-quality illustrations. In addition to these detailed descriptions, ear embryology and anatomy, psychological issues, postoperative care, possible risks and complications, and outcomes are extensively covered in order to provide the reader with a state of the art account of all aspects of cosmetic otoplasty.
  • Digital
    editors, Vicki S. Good, DNP, RN, CENP, CPPS, System Director Clinical Quality/Safety, CoxHealth, Springfield, Missouri, Peggy L. Kirkwood, MSN, RN, ACNPC, CHFN, AACC, Cardiovascular and Palliative Care Nurse Practitioner, Mission Hospital, Mission Viejo, California.
    R2Library2018
    Learn to effectively address life-threatening and potentially life-threatening patient conditions, with Advanced Critical Care Nursing, 2nd Edition. Endorsed by the American Association of Critical-Care Nurses (AACN), this comprehensive, nursing-focused text centers on the clinical reasoning process as it helps you comprehend, analyse, synthesize, and apply advanced critical care knowledge and concepts. The book is organized within the structure of body systems along with synthesis chapters that address patient conditions involving multiple body systems. Numerous illustrations and graphs plus unfolding case studies further aid your understanding and help you apply text content. In all, Advanced Critical Care Nursing is the must-have resource dedicated to helping you oversee or care for critical care patients in any practice setting. -- Provided by publisher.
  • Print
    Katarina T. Borer.
    Unique properties of endocrine and autonomic messengers -- Activation of non-hormonal signaling during exercise -- Autonomic and hormonal control of the cardiorespiratory system -- Body fluid balance -- Hormones and fuel use in exercise -- Hormonal control of energy expenditure and intake -- Exercise and reproductive hormones -- Hormonal mediation in training adaptations -- Exercise and endocrine rhythms.
  • Digital
    edited by Peter J. Verveer.
    Springer2015
    The physical basis of total internal reflection fluorescence (TIRF) microscopy and its cellular applications -- Two-photon excitation microscopy and its applications in neuroscience -- Live spheroid formation recorded with light sheet-based fluorescence microscopy -- Fluorescence microscopy-based RNA interference screening -- Fluorescence resonance energy transfer microscopy (FRET) -- Localizing protein-protein interactions in living cells using fluorescence lifetime imaging microscopy -- Analysis of biomolecular dynamics by FRAP and computer simulation -- Fluorescence correlation spectroscopy -- Homo-FRET imaging highlights the nanoscale organization of cell surface molecules -- Practical structured illumination microscopy -- 4Pi microscopy of the nuclear pore complex -- Application of STED microscopy to cell biology questions -- Three-dimensional photoactivated localization microscopy with genetically expressed probes -- Direct stochastic optical reconstruction microscopy (dSTORM) -- Optogenetics: Optical control of a photoactivatable Rac in living cells.
  • Digital
    Jonathan Martin Geisinger.
    The ability to precisely modify the genome with high efficiency in a directed manner is dependent on generating and exploiting a double-strand break in DNA. The tools available to generate double-strand breaks include the recombinases and resolvases, the phage integrases, the homing endonucleases, zinc finger nucleases, transcription activator-like effector nucleases, and the CRISPR/Cas9 system, the most recently developed tool. These tools allow for in-depth studies of the function of genes and genome structure, the generation of organisms bearing economically important bio-synthetic pathways, and the development of novel gene and cell therapies for addressing previously untreatable diseases. Taking full advantage of each tool and knowing when to use each one requires a thorough understanding of how the tool functions. For most of the genome engineering toolkit, this understanding has been achieved. The CRISPR/Cas9 system, however, has been assumed to function in the same manner as the zinc finger and transcription activator-like effector nucleases despite generating blunt-end double-strand breaks rather than staggered breaks. This difference is important to understanding how Cas9-mediated double-strand breaks are repaired, and, thus, how best to exploit these breaks for genome engineering. This thesis illustrates the importance understanding how each genome engineering tool functions in developing advantageous methods for gene and cell therapies.
  • Digital
    Ahmad A. Aref, Rohit Varma, editors.
    Springer2015
    1 Advanced Glaucoma Surgery: An Overview -- 2 Trabecular Micro-bypass Stent for the Treatment of Co-existent Cataract and Mild Open-Angle Glaucomas -- 3 Trabectome-Mediated Ab Interno Trabeculectomy for Secondary Glaucoma or as a Secondary Procedure -- 4 Lens Extraction in Angle Closure Glaucoma -- 5 Gonioscopy Assisted Transluminal Trabeculotomy (GATT) for the Treatment of Adult and Developmental Glaucomas -- 6 Ab-Interno Subconjunctival Glaucoma Implant for Advanced Open-Angle Glaucomas -- 7 Nonpenetrating Glaucoma Surgery -- 8 Endoscopic Cyclophotocoagulation in the Treatment of Plateau Iris and Angle Closure Glaucomas -- 9 Ex-PRESS Miniature Glaucoma Shunt for the Treatment of Uveitic Glaucomas -- 10 Surgical Management of Normal Tension Glaucoma -- 11 Glaucoma Drainage Implant Surgery Combined with Pars Plana Vitrectomy and KPro Implantation -- 12 The Modified Schocket Procedure -- 13 Ab-interno Bleb Needling -- 14 Drainage of Choroidal Effusions -- 15 Surgical Management of Malignant Glaucoma -- Supplemental Video Table of Contents -- 1. Video 3.1. Trabectome Procedure with Goniosynechiolysis -- 2.Video 5.1. Gonioscopy Assisted Transluminal Trabeculotomy (GATT) -- 3.Video 6.1. Xen Gel implantation -- 4. Video 7.1. Non-Penetrating Glaucoma Surgery -- 5. Video 9.1. Ex-Press Shunt Implantation -- 6. Video 10.1. Trabeculectomy with adjunctive Mitomycin-C -- 7. Video 11.1. Glaucoma Drainage Implant Surgery Combined with Pars Plana Vitrectomy and KPro Implantation -- 8. Video 12.1. Modified Schocket Procedure -- 9. Video 13.1. Ab-Interno Trabeculectomy Revision -- 10. Video 15.1. .
  • Digital
    Lawrence Robbins.
    Springer2015
    Chapter 1. Migraine and Headache: General -- Chapter 2. Refractory(Difficult to Treat) Headache -- Chapter 3. Child and Adolescent Headaches -- Chapter 4. Cluster Headache. Chapter 5. Psychological Comorbidities -- Chapter 6. Case Studies -- Chapter 7. Miscellaneous.
  • Digital
    edited by Ashutosh Tiwari, Biosensors and Bioelectronics Centre, Linkping University, Sweden.
    Wiley2014
    "Advanced Healthcare Nanomaterials summarises the current status of knowledge in the fields of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, up and coming bio-engineering devices"-- Provided by publisher.
  • Digital
    Francesco M. Sacerdoti, Antonio Giordano, editors.
    Springer2016
    Test equipment in biology laboratories -- Automation software (acquisition, control and analysis concepts) -- Digital Image Processing (F. Sacerdoti) -- Statistic Analysis.-€ Cell identification -- Cell classification & Counting.-€ Cell aggregation -- Skin and body analysis (F. Melchi & F.M. Sacerdoti) -- Space or Space Simulation equipments -- Off-the-shelf Analysis Software. Commercial & Open Source -- Commercial Test Equipment -- Best practices.
  • Digital
    Hideomi Watanabe, Misako Koizumi (eds.).
    Springer2010
  • Digital
    Namir Katkhouda.
    Springer2010
    General concepts -- Cholecystectomy -- Common bile duct explorations and bilioenteric anastomosis -- Laparoscopic liver surgery -- Esophageal surgery -- Gastric surgery -- Appendectomy -- Colorectal procedures -- Small bowel obstruction -- Inguinal hernia repair -- Incisional and ventral hernia repair including component separation -- Splenectomy (total and partial) and splenopancreatectomy -- Adrenalectomy -- Bariatric surgery -- Single-access laparoscopic surgery (SALS) -- Advanced laparoscopic suturing techniques.
  • Digital
    S.B. Brandes, A.F. Morey, editors ; foreword by Guido Barbagli.
    Springer2014
    Since the publication of the first edition of Urethral Reconstructive Surgery, important refinements have been added to the urologic surgical armamentarium. Extensively revised and updated, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition guides urologists in a practical manner on how to evaluate and manage complex urethral and male genital reconstructive challenges. Chapters have been added on wound healing, synchronous urethral strictures, non-transecting anastomotic urethroplasty (including muscle and vessel sparing), overlapping buccal grafts, male urethral slings, genital skin grafting, Peyronies surgery, priapism, pediatric strictures, and prosthetics. Such chapters greatly strengthen the overall appeal of the book. The volume closes with a new comprehensive appendix of preferred instruments. With broad contributions by international authorities in reconstructiveurologic surgery, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition is a valuable resource for all urologists, from residents to reconstructive surgeons.
  • Digital
    edited by Lázaro Luís Faria do Amaral, Asim K. Bag, Fabricio Guimarães Gonçalves, Prasad B. Hanagandi, associate editor, Suzanne Byan Parker.
    Cambridge2016
  • Digital
    Ruth Tappen, EDD, RN, FAAN, Professor, Christine E. Lynn Eminent Scholar in Nursing, Christine E. Lynn College of Nursing, Florida Atlantic University, Boca Raton, Florida.
    R2Library2016
    "Teaches students how to prepare research proposals and carry out research studies using a practical approach. The second edition puts a greater emphasis on evidence-based practice, quality improvement, and the use of aggregate data. The outstanding feature of this text is its reality-based approach to the actual conduct of research. The text also reflects current practice and current thinking about research and integrates qualitative and quantitative methods, including emerging mixed methods"-- Provided by publisher.
  • Digital
    editor, Miranda Lomer.
    Wiley2014
    Physiology and function of the gastrointestinal and hepatobiliary tract -- Dietary components relevant to gastrointestinal health -- Gastrointestinal disorders -- Hepatobiliary disorders.
  • Digital
    edited by Mary Hickson, Sara Smith.
    Wiley2018
    Background to undernutrition -- Identification of undernutrition -- Nutrition requirements in nutrition support -- Nutritional interventions to prevent and treat undernutrition -- Undernutrition and nutritional support in clinical specialities.
  • Digital
    [edited by] Catherine Hankey.
    Wiley2018
    "This addition to the British Dietetic Association Advanced Nutrition and Dietetics book series is written for clinicians and researchers who work with any aspect of obesity and its comorbid conditions. Featuring contributions from leading researchers and practitioners from around the globe Advanced Nutrition and Dietetics in Obesity offers a uniquely international perspective on what has become a worldwide public health crisis. Chapters cover a full range of new ideas and research on the underlying drivers of obesity in populations including discussions on the genetic and clinical aspects of obesity, along with expert recommendations on how to effectively manage and prevent this chronic and persistent disease. Providing a comprehensive overview of the key literature in this field, Advanced Nutrition and Dietetics in Obesity is an invaluable resource for all those all those whose work should or does embrace any aspect of obesity"--Provided by publisher.
  • Digital
    edited by Barbara Holmes Gobel, MS, RN, AOCN, Shirley Triest-Robertson, PhD, AOCNS, ACHPN, ACNSBC, RN-BC (Pain), Wendy H. Vogel, MSN, FNP, AOCNP.
    R2Library2016Limited to 1 simultaneous user
    Cancer prevention, screening, and early detection -- Genetic risk -- Cancer diagnosis and staging -- Chemotherapy, targeted biotherapy, and molecular therapy -- Surgery -- Radiation therapy -- Blood and marrow stem cell transplantation -- Complementary and integrative therapies -- Clinical research -- Pain, fatigue, and cognitive impairment -- Myelosuppression -- Cardiac and pulmonary toxicities -- Gastrointestinal, genitourinary, and hepatic toxicities -- Neurologic, ocular, and dermatologic toxicities -- Metabolic emergencies -- Structural oncologic emergencies -- Psychosocial management -- Cancer survivorship -- Palliative and end-of-life care -- Roles of the oncology advanced practice nurse -- Professional practice of advanced practice nurses -- Test questions.
  • Digital
    edited by David Ricketts, David Bartlett.
    ScienceDirect2011
    Management of dental caries / David Ricketts, Graham Chadwick and Andrew Hall -- Periodontal disease / Angela Gilbert -- Endodontic problems in advanced operative dentistry / William Saunders -- Tooth wear / David Bartlett -- Aesthetic problems / David Bartlett -- Occlusion / David Ricketts -- Cores / Carol Tait and David Rickett -- Gold crowns / John Radford, Brian Stevenson -- Gold restorations / Graham Chadwick, John Radford and David Ricketts -- Metal ceramic crowns / Brian Stevenson -- All ceramic crowns / Andrew Hal and Graham Chadwick -- Inlays, onlays, and veneers / David Bartlett and David Ricketts -- Impression materials and techniques / David Ricketts -- Provisional restorations / John Radford and David Ricketts -- Getting the appearance correct / Brian Stevenson -- Complex multiple fixed and combined fixed and removable prosthodontics / David Bartlett and David Ricketts -- When and how to replace missing teeth / David Ricketts -- Minimal preparation (resin retained) bridges / David Ricketts -- Conventional bridges / David Bartlett and David Ricketts.
  • Digital
    Frank A. Carey and Richard J. Sundberg.
    Springerpt. A, 2007
    Springerpt. B, 2007
    pt. A. Structure and mechanisms -- pt. B. Reactions and synthesis.
  • Digital
    edited by Martin Samuels, Sue Wieteska.
    Wiley2016
    This course book gives guidance on life-threatening emergencies in children. It covers recognition of the seriously ill child, basic life support, treatment of shock, in a structured approach to the seriously injured child.
  • Digital
    edited by Matthew D. McEvoy, Cory M. Furse.
    Oxford Medicine Online2017
    A high-yield, clinically-relevant resource for understanding the epidemiology, pathophysiology, assessment, and management of a wide variety of perioperative emergencies. Each chapter opens with a clinical case, followed by a discussion of the relevant evidence. Case-based learning discussion questions, which can be used for self-assessment or in the classroom, round out each chapter. This work is an ideal resource for trainees, clinicians, and nurses who work in the perioperative arena, from the operating room to the postoperative surgical ward.
  • Digital
    Sofia Llahana [and 3 more], editors.
    Springer2019
    This book provides a comprehensive guide for nurses practicing in any area of endocrinology and at any level of expertise. Endocrinology Nursing is a fast-developing specialty with nurses performing advanced roles and expanding their practice to run independent nurse-led services. Supported by the European Society for Endocrinology (ESE) and edited by members of the ESE Nurses Working Group, this is the first book ever published specifically for endocrine nurses. It is also an excellent resource for endocrinology specialty trainees, general practitioners, medical and nursing students, expert patients and nurses working in specialties such as fertility, osteoporosis, oncology, obesity, urology and gynaecology, who look after patients with endocrine-related disorders. This volume includes 13 sections and 69 chapters providing a comprehensive overview of adult and paediatric endocrinology but also a section on advanced practice, role development and nursing research. It has been written by an international team of more than 100 eminent nurses, physicians, surgeons, psychologists and other healthcare professionals, which makes this book a valuable resource for any multidisciplinary team. Many patient advocacy groups have contributed with case studies which emphasises the close working relationships with patients.
  • Digital
    Kelley M. Anderson, PhD, FNP, editor.
    R2Library2016
    Overview of cardiovascular care -- Chronic cardiovascular conditions -- Cardiac electrophysiology -- Vascular disorders -- Acute cardiovascular conditions -- Cardiovascular diagnostics -- Cardiovascular therapeutics and interventions.
  • Print
    [edited by] Ann B. Hamric, Judith A. Spross, Charlene M. Hanson.
    Status: Not Checked Out
    A brief history of advanced practice nursing in the United States / Arlene W. Keeling -- Conceptualizations of advanced practice nursing / Judith A. Spross and Marjorie Thomas Lawson -- A definition of advanced practice nursing / Ann B. Hamric -- Role development of the advanced practice nurse / Karen A. Brykczynski -- Direct clinical practice / Mary Fran Tracy -- Expert coaching and guidance / Judith A. Spross -- Consultation / Anne-Marie Barron and Patricia A. White -- Research / Judith A. DePalma -- Clinical, professional, and systems leadership / Judith A. Spross and Charlene M. Hanson -- Collaboration / Charlene M. Hanson and Judith A. Spross -- Ethical decision making / Ann B. Hamric and Sarah A. Delgado -- The clinical nurse specialist / Patricia S.A. Sparacino and Cathy C. Cartwright -- The primary care nurse practitioner / Ann Reid Anderson and Eileen T. O'Grady -- The acute care nurse practitioner / Marilyn Hravnak ... [et al.] -- The blended role of the clinical nurse specialist and the nurse pracitioner / Patricia M. Hentz and Ann B. Hamric -- The certified nurse-midwife / Cheryl A. Sarton and Maureen A. Kelley -- The certified registered nurse anesthetist / Margaret Faut-Callahan and Michael J. Kremer -- Evolving and innovative opportunities for advanced practice nursing / Jeanne Salyer and Ann B. Hamric -- Business planning and reimbursement mechanisms / Charlene M. Hanson and Sally D. Bennett -- Marketing and contracting considerations / Donna R. Hodnicki -- Understanding regulatory, legal, and credentialing requirements / Charlene M. Hanson -- Health policy issues in changing environments / Eileen T. O'Grady and Jean E. Johnson -- Strengthening advanced practice nursing in organizational structures : administrative considerations / Brenda M. Nevidjon and Cynthia J. Simonson -- Outcomes evaluation and performance improvement : an integrative review of research on advanced practice nursing / Gail L. Ingersoll -- Outcomes evaluation and performance improvement : using data and information technology to improve practice / Vicky A. Mahn-DiNicola.
  • Digital
    edited by Susan M. DeNisco, Anne M. Barker.
    R2Library2016Limited to 1 simultaneous user
    "Advanced Practice Nursing: Essential Knowledge for the Profession, Third Edition is a core advanced practice text used in both Master's Level and DNP programs. The Third Edition is a unique compilation of existing chapters from a variety of high-level Jones & Bartlett Learning works creating a comprehensive and well-rounded resource for the advanced practice nursing student. Similar to the previous edition, The Third Edition is framed around the AACN's Master's Essentials as well as the Essentials for Doctoral Education featuring the most up-to-date content on each set of Essentials. Throughout the Third Edition the authors address the rapid changes in the health care environment with a special focus on health care finance, electronic health records, quality and safety as well as emerging roles for the advanced practice nurse. Patient care in the context of the advanced nursing role is also discussed."--Publisher's website.
  • Digital
    [edited by] Lucille A. Joel, EdD, APN, FAAN, Distinguished Professor, Rutgers, The State University of New Jersey, School of Nursing, New Brunswick-Newark, New Jersey.
    R2Library2018Limited to 1 simultaneous user
    Unit 1: The evolution of advanced practice -- Advanced practice nursing: doing what has to be done -- Emerging roles of the advanced practice nurse -- Role development: a theoretical perspective -- Educational preparation of advanced practice nurses: looking to the future -- Global perspectives on advanced nursing practice -- Unit 2: The practice environment -- Advanced practice nurses and prescriptive authority -- Credentialing and clinical privileges for the advanced practice registered nurse -- The kaleidoscope of collaborative practice -- Participation of the advanced practice nurse in health plans and quality initiatives -- Public policy and the advanced practice registered nurse -- Resource management -- Mediated roles: working with and through other people -- Unit 3: Competency in advanced practice -- Evidence-based practice -- Advocacy and the advanced practice registered nurse -- Case management and advanced practice nursing -- The advanced practice nurse and research -- The advanced practice nurse: holism and complementary and integrative health approaches -- Basic skills for teaching and the advanced practice registered nurse -- Culture as a variable in practice -- Conflict resolution in advanced practice nursing -- Leadership for APNs: if not now, when? -- Information technology and the advanced practice nurse -- Writing for publication -- Unit 4: Ethical, legal, and business acumen -- Measuring advanced practice nurse performance: outcome indicators, models of evaluation, and the issue of value -- Advanced practice registered nurses: accomplishments, trends, and future development -- Starting a practice and practice management -- The advanced practice nurse as employee or independent contractor: legal and contractual considerations -- The law, the courts, and the advanced practice registered nurse -- Malpractice and the advanced practice nurse -- Ethics and the advanced practice nurse.
  • Digital
    Laurie Kennedy-Malone, PhD, GNP-BC, FAANP, FGSA, Professor of Nursing, School of Nursing, University of North Carolina at Greensboro, Greensboro, North Carolina, Lori Martin-Plank, PhD, FNP-BC, NP-C, GNP-BC, FAANP, Clinical Associate Professor, College of Nursing, University of Arizona, Tucson, Arizona, Evelyn Groenke Duffy, Associate Professor, Director of the Adult-Gerontology Primary Care Nurse Practitioner Program, Associate Director of the University Center on Aging and Health, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio.
    R2Library2019
    Explore effective ways to enhance the wellness and independence of older adults across the wellness-illness continuum, including acute, primary, and long-term care. From an overview of the theories of aging and assessment through the treatment of disorders, including complex illnesses, this evidence-based book provides the comprehensive gerontological coverage you need to prepare for your role as an Advanced Practice Nurse. You<U+0019>ll be prepared for boards and for practice. -- From product description.
  • Digital
    edited by Constance Dahlin, Patrick J. Coyne, Betty R. Ferrell.
    Oxford Medicine Online2016
    This is a comprehensive resource that addresses all aspects of palliative care, providing advanced practice content and practical reference for clinical practice across all settings.
  • Digital
    Sudhir Diwan, Timothy R. Deer, editors.
    Springer2018
    Section I: Advanced Spinal Interventions -- 1. Advanced Spinal Mapping: An Interventional Continuum for Axial, Radicular, and Dorsal Root Ganglion-Related Pain -- 2. MILD: Percutaneous Lumbar Decompression -- 3. Superion: An Indirect Lumbar Decompression -- 4. Minimally Invasive Discectomy: Transforaminal Approach -- 5. Minimally Invasive Percutaneous Endoscopic Discectomy: Transdiscal Approach -- 6. Minimally Invasive Facet Fusion -- 7. Vertebral Augmentation: Vertebroplasty and Kyphoplasty -- Section II: Advanced Neuromodulation -- 8. Neuromodulation: Mechanisms of Action -- 9. Anatomy of Neuromodulatory Targets: Central Nervous System and the Periphery -- 10. Neuromodulation: Optimizing Surgical Outcomes and Risk Reduction -- 11. Extracranial Peripheral Nerve and Peripheral Nerve Field Stimulation for Headache: Trialing -- 12. Extracranial Peripheral Nerve Field and Peripheral Nerve Stimulation for Headache: Permanent Implant -- 13. Intracranial Neuromodulation: Deep Brain Stimulation for Pain -- 14. Spinal Cord Stimulation, Cervical: Trialing -- 15. Spinal Cord Stimulation: Thoracic and Lumbar-Trial -- 16. Spinal Cord Stimulation-Hybrid Lead Array: Epidural and Peripheral Nerve Field Stimulation Trialv -- 17. Hybrid Neuromodulation -- 18. Permanent Percutaneous Spinal Cord Stimulator Implantation: Cervical/Lumbar -- 19. Spinal Cord Stimulation for Chronic Abdominal Pain -- 20. Spinal Cord Stimulation: Pelvic Pain -- 21. Truncal Stimulation Trial and Implant -- 22. Peripheral Nerve Stimulation for the Painful Extremity -- 23. Advanced Neuromodulation Techniques: Dorsal Root Ganglion Stimulation -- 24. High-Frequency Stimulation -- 25. Burst Stimulation: An Innovative Waveform Strategy for Spinal Cord Stimulation -- 26. Novel Waveforms -- 27. Transcutaneous Vagus Nerve Stimulation: Novel Treatment Strategies -- 28. Sacral Stimulation for Pelvic Pain -- 29. Intrathecal Drug Delivery: Pharmacokinetics and Dynamics -- 30. Patient Selection for Drug Delivery System Implantation -- 31. Intrathecal Drug Delivery: Medication Selection -- 32. Intrathecal Drug Delivery: Trialing -- 33. Intrathecal Drug Delivery: Implantation -- 34. Intrathecal Drug Delivery Maintenance: Refill and Programming -- 35. Intrathecal Drug Delivery Maintenance: Catheter Evaluation -- 36. Intrathecal Drug Delivery: Innovation -- Section III: Advanced Regenerative Medicine -- 37. History of Regenerative Medicine -- 38. Platelet-Rich Plasma -- 39. Alpha-2-Macroglobulin: Protease Inhibitor Treatment (PRP Variant) -- 40. Bone Marrow Derived Stem Cells and their Application in Pain Medicine -- 41. Adipose-Derived Stromal Stem Cells -- 42. Intradiscal Biologic Treatments: Allogeneic Stem Cells -- 43. Intradiscal Biologic Treatments: Intra-annular Fibrin Disc Sealant -- 44. Amniotic Tissue -- 45. Platelet-Rich Plasma (PRP): Procedural Techniques for Musculoskeletal Injuries -- 46. Technical Aspects of Regenerative Injection Therapy -- 47. Platelet-Rich Plasma Therapy: An Overview.
  • Digital
    Shirley Pease, Thomas L. Saunders, editors ; ISTT, International Society for Transgenic Technologies.
    Springer2011
    Patent and licensing issues in transgenic technology / Karen S. Canady -- Global resources : including gene trapped ES cell clones -- is your gene already knocked out / Lluis Montoliu -- Designing transgenes for optimal expression / Eduardo Molto, Cristina Vicente-Garcıa, and Lluis Montoliu -- Gene targeting vector design for embryonic stem cell modifications / Thomas L. Saunders -- Transgenic production benchmarks / Thomas J. Fielder and Lluis Montoliu -- Generation of transgenic mice by pronuclear microinjection / Katja Becker and Boris Jerchow -- Generation of transgenic rats using microinjection of plasmid DNA or lentiviral vectors / Severine Menoret ... [et al.] -- Generation of transgenic animals by use of YACs / Almudena Fernandez, Diego Munoz, and Lluis Montoliu -- BAC transgenes, DNA purification, and transgenic mouse production / Michael G. Zeidler, Margaret L. Van Keuren, and Thomas L. Saunders -- Generation of transgenic animals with lentiviral vectors / Carlos Lois -- Vertebrate transgenesis by transposition / Aron Geurts, Darius Balciunas, and Lajos Mates -- Rat spermatogonial stem cell-mediated gene transfer / Karen M. Chapman ... [et al.] -- Mouse cloning by nuclear transfer / Sayaka Wakayama, Nguyen Van Thuan, and Teruhiko Wakayama -- Gene targeting in embryonic stem cells / Elizabeth D. Hughes and Thomas L. Saunders -- Importance of mouse ES cell line selection / Wojtek Auerbach and Anna B. Auerbach -- Tetraploid complementation assay / Marina Gertsenstein -- Combining ES cells with embryos / Elizabeth Williams ... [et al.] -- Derivation of murine ES cell lines / Kristina Nagy and Jennifer Nichols -- Rat embryonic stem cell derivation and propagation / Ping Li ... [et al.] -- Induced pluripotency : generation of iPS cells from mouse embryonic fibroblasts / Han Li ... [et al.] -- Preparation and analysis of DNA for use in transgenic technology / Anna B. Auerbach, Peter J. Romanienko, and Willie H. Mark -- Colony management / Karen Brennan -- Cryopreservation / B. Pintado and J. Hourcade -- Shipment of mice and embryos / Shirley Pease -- Pathogen-free mouse rederivation by IVF, natural mating and hysterectomy / J.M. Sztein, R.J. Kastenmayer, and K.A. Perdue -- Refinement, reduction, and replacement / Jan Parker-Thornburg.
  • Digital
    edited by Donald Armstrong.
    Springerv.1 (2008)
    Springerv.2 (2010)
    Springerv.3 (2015)
  • Digital
    Anthony Erian, Melvin A. Shiffman (editors).
    Springer2012
  • Digital
    Amy L. Halverson, David C. Borgstrom, editors.
    Springer2015
    This unique reference fulfills the unmet need of a textbook that addresses the scope of practice for surgeons practicing in rural regions. The text provides up-to-date content covering a wide breadth of topics relevant to surgical care in rural areas, with focus on the surgical diseases that are often treated by surgical subspecialists in the urban setting. Written by experts in each subspecialty, the text focuses on procedural aspects of surgical patient care. The first section discusses practice issues unique to rural surgery and provides an overview of applying principles of quality improvement to surgical practice. Subsequent chapters cover specific surgical procedures. Each chapter includes a brief discussion of indications and contraindications for surgery. The surgical technique is described with attention to important anatomic details. Key portions of the procedure are highlighted including potential complications and how to avoid them. Procedure specific perioperative care is also discussed. Supported with ample illustrations and images, Advanced Surgical Techniques for Rural Surgeons is a valuable resource for surgeons currently in practice or preparing to practice in a rural area, as well as surgical technicians, surgical nurse practitioners, and physician's assistants.
  • Digital
    Yi-Wei Tang, Charles W. Stratton, editors.
    Springer2013
  • Digital
    Mehmet Kocaoğlu, Hiroyuki Tsuchiya, Levent Eralp, editors.
    Springer2015
    As a result of recent advances in surgical techniques and implant technology it is now possible to perform limb reconstruction in patients with a range of congenital, posttraumatic, and postinfection pathologies. This book is a clear, practical guide to the state-of-the-art surgical procedures employed in limb reconstruction for diverse conditions. It includes precise descriptions of the techniques themselves, accompanied by numerous helpful drawings and photographs. Pearls and pitfalls are highlighted, and thorough advice is also provided on indications, preoperative planning, and postoperative follow-up. The editors have carefully selected the contributors based on their expertise, and many of the authors were themselves responsible for developing the techniques that they describe.
  • Digital
    Ovunc Bardakcioglu, editor.
    Springer2015
    This book bridges gap between the practicing community of surgeons and the surgical innovators, and it provides a foundation for all classic and new techniques in minimally invasive colorectal surgery. It provides tips and tricks that allow the user to move up the learning curve, manage difficult scenarios, overcome challenges, increase the utilization of minimal invasive techniques and decrease the conversion to open surgery. By enhancing the surgical tool box, the surgeon will be able to progress from the novice to the master. Rather than describing operative procedures, which may be very biased by an individual author, the guide provides alternative building blocks of various difficulty for different procedures, thereby allowing the surgeon to tailored surgery to patient and surgeon's own comfort level and experience. Advanced Techniques in Minimally Invasive and Robotic Colorectal Surgery is an inspirational guide for the innovator of the future. This text allows surgeons of all levels to better adapt to inevitable changes in future techniques. Advanced Techniques in Minimally Invasive and Robotic Colorectal Surgery is of great value to general surgeons, colon and rectal surgeons, minimally invasive surgeons as well as residents and fellows.
  • Digital/Print
    M. Cristina Vega, editor.
    Digital : Springer2016
    Print2016
  • Digital
    edited by Andrea Gaggioli, Emily A. Keshner, Patrice L. (Tamar) Weiss, and Giuseppe Riva.
    eBook Comp Acad2009
    Sect. I. Advanced Technologies in Rehabilitation: An Introduction -- Sect. II. Training and Technology as an Aid in Functional Gaines -- Sect. III. Rules that Govern Recovery of Function -- Sect. IV. Using the Body's Own Signals to Augment Therapeutic Gaines -- Sect. V. Technology Incorporates Cognition and Action -- Sect. VI. Technology Enhances the Impact of Rehabilitation Programs.
  • Digital
    volume editors Marco Cappa, Stefano Cianfarani, Lucia Ghizzoni, Sandro Loche, Mohamad Maghnie.
    Karger2016
    Toward automation of insulin delivery : management solutions for type 1 diabetes / Nimri, R., Phillip, M. -- Islet transplantation in pediatric patients : current indications and future perspectives / Bertuzzi, F., Antonioli, B., Tosca, M.C., Galuzzi, M., Bonomo, M., Marazzi, M., Colussi, G -- Glucagon-like peptide-1 receptor agonist treatment for pediatric obesity / Kelly, A.S -- Docosahexaenoic acid and its role in g-protein-coupled receptor 120 activation in children affected by nonalcoholic fatty liver disease / Della Corte, C., Mosca, A., Ionata, A., Nobili, V -- Noninvasive prenatal diagnosis of congenital adrenal hyperplasia / Khattab, A., Yuen, T., Sun, L., Yau, M., Barhan, A., Zaidi, M., Lo, Y.M.D., New, M.I -- Recent advances in hydrocortisone replacement treatment / Mallappa, A., Debono, M -- Experience with the histrelin implant in pediatric patients / Eugster, E.A -- Different medications for hypogonadotropic hypogonadism / Rastrelli, G., Vignozzi, L., Maggi, M -- Long-acting growth hormone : an update / Saenger, P.H., Mejia-Corletto, J -- C-type natriuretic peptide analog as therapy for achondroplasia / Legeai-Mallet, L -- Therapeutic neuroendocrine agonist and antagonist analogs of hypothalamic neuropeptides as modulators of the hypothalamic-pituitary-gonadal axis / Newton, C.L., Anderson, R.C., Millar, R.P -- Aromatase inhibitors in the treatment of short stature / Hero, M -- Gene therapy for rare central nervous system diseases comes to age / Aubourg, P -- Novel therapeutic targets and drug candidates for modifying disease progression in adrenoleukodystrophy / Pujol, A.
  • Digital
    Mira Milas, Susan J. Mandel, Jill E. Langer, editors.
    Springer2017
    Selection and Set-up of Ultrasound in Point-of-Care Medical Practice -- Principles of Ultrasound Relevant for Advanced Sonographers -- Understanding Knobology and Optimal Settings for Clinician-Performed Ultrasound -- The Use of Vascular Ultrasound and Doppler Settings in Thyroid and Parathyroid Diseases -- 3D Ultrasound -- Elastography: Applications and Limitations of New Technology -- Anatomy: Normal Landmarks for Conducting Thyroid and Parathyroid Ultrasound -- Pattern Recognition for Cancer Risk-Stratification in Ultrasound of Thyroid Nodules -- Pattern Recognition: Multinodular Goiter -- Pattern Recognition: Hashimoto's Thyroiditis -- Pattern Recognition: Graves' Disease -- Ultrasound Imaging of Embryological Variants and Anomalies of the Thyroid -- Artifacts and Eponyms in Thyroid Ultrasound -- Features of Malignancy in Thyroid Nodules -- Pattern Recognition: Calcifications and Hyperechoic Foci -- Sonographic Features and Management of Cervical Nodal Metastasis -- Evaluation of the Central Neck: Why, When, How -- Evaluation of the Lateral Cervical Nodal Basins: Why, When, How -- Imaging of the Re-operative or "Empty" Neck -- Anatomic Appearance and Distribution of Abnormal Parathyroid Glands -- Ultrasound as a Localization Technique in Primary Hyperparathyroidism -- Ultrasound in Scenarios of Multigland Parathyroid Disease -- The Procedure of Ultrasound-guided Percutaneous Biopsy of Thyroid and Parathyroid Lesions -- Thyroid FNA: When to Perform and When to Avoid -- Parathyroid FNA: Indications and Interpretation -- Pearls and Pitfalls of Ultrasound-Guided Fine Needle Aspiration -- Alcohol Ablation of Thyroid and Parathyroid Lesions -- HIFU: High-Frequency Ultrasound Ablation for Thyroid and Parathyroid Disease -- Laryngeal Ultrasound -- The Role of Ultrasound in Determining Eligibility for Remote Access and Robotic Surgery -- Intraoperative Use of Ultrasound in Thyroid and Parathyroid Surgery -- Pediatric Thyroid and Parathyroid Ultrasound -- Ultrasound for Surgeons: What I learned from Lifetime Practice -- Ultrasound for Endocrinologists: What I learned from Lifetime Practice -- Ultrasound for Radiologists: What I learned from Lifetime Practice -- Ultrasound for Primary Care Practitioners -- Ultrasound as a Component of the Medical School Curriculum -- Innovations on the Horizon for Ultrasound -- Key Components of a Comprehensive Thyroid and Parathyroid Ultrasound Report -- Pathways to Ultrasound Certification.
  • Digital
    John M. Butler.
    ScienceDirect2012
    Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues. Contains the latest information - hot-topics and new technologies Well edited, attractively laid out, and makes productive use of its four-color format Author John Butler is ranked as the number one "high-impact author in legal medicine and forensic science, 2001 to 2011" by ScienceWatch.com.
  • Digital
    Xiaobing Fu, Liangming Liu, editors.
    Springer2017
    This book discusses different aspects of trauma surgery, ranging from the various types of trauma and their management, infection, sepsis and inflammation to tissue injury and repair in trauma. It discusses cellular, molecular and genetic research findings and their role in pathogenesis in trauma and injury. In addition, it highlights the translational application of advanced theories and technologies in the management of trauma patients. This book is a valuable resource for anyone involved in the management of severe trauma damage to tissues wanting to reduce early mortality and improve patients' quality of life. Editor Xiaobing Fu is a professor and director of the Key Laboratory of Wound Repair and Regenerative Medicine of PLA, The First Affiliated Hospital of the PLA General Hospital, Beijing, China. Professor Fu is also an academician of Chinese Academy Engineering. Editor Liangming Liu is a professor at the State Key Laboratory of Trauma, Burns, and Combined Injury, Daping Hospital, Third Military Medical University, Chongqing, China.
  • Digital/Print
    Mieczyslaw Pokorski, editor.
    Digital : Springer2016
    Print2016
    Oxygen sensing mechanisms: a physiological penumbra -- Nocturnal blood pressure variability in patients with obstructive sleep apnea syndrome -- Frequent attenders with chronic respiratory diseases in primary care settings -- Damaging effects of cannabis use on the lungs -- Neurogenic pulmonary edema in aneruysmal subarachnoid hemorrhage -- Clinical implications of hepatocyte growth factor, interleukin-20 and interleukin-22 in serum and bronchoalveolar fluid of patients with non-small cell lung cancer -- Expression of ceramide galactosyltransferase (UGT8) in primary and metastatic lung tissues of non-small-cell lung cancer -- Antibiotic treatment of hospitalized patients with pneumonia complicated by Clostridium Difficile infection -- Concha bullosa in paleoanthropological material -- IgA nephropathy in children: a multicenter study in Poland -- Index.
  • Digital/Print
    Alisa G. Woods, Costel C. Darie, editors.
    Digital : Springer2014
    Print2014
    "This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine"--Publisher's description.
  • Digital
    Alisa G. Woods, Costel C. Darie, editors.
    Springer2019
    This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.
  • Digital
    Thomas Sushil John.
    Magnetic resonance imaging (MRI) is a versatile imaging tool that can be used to detect changes in brain hemodynamics that accompany neuronal activity. This ability to observe both anatomy and the structures that participate in specific functions is often referred to as functional magnetic resonance imaging (fMRI). Echo planar imaging (EPI) is the most widely used data acquisition method for fMRI. Functional images are often distorted because EPI is highly sensitive to field inhomogeneities, eddy currents, and gradient delays. These distortions often lead to image misregistration, and this is an impediment to correctly interpreting functional studies, and to neurosurgical planning. Many methods have been developed to address this. However, none yields anatomical and functional images that may be directly overlaid onto each other with no post-processing. This dissertation demonstrates that automatic, inherent self co-registration is achieved when optimized flyback EPI with echo time shifting (ETS) is used for both functional and anatomical images. fMRI experiments validate the proposed method, and the result is high-quality functional and high-resolution anatomical images that are inherently self co-registered. EPI acquisitions are also prone to timing and phase errors that give rise to image ghosting. ETS is an effective ghost correction method in EPI. Although ETS corrects for ghosting in a robust, non-iterative, and automatic manner, it does so at the expense of increasing total scan time. This dissertation proposes a simple, yet effective scheme to increase the efficiency of ETS by acquiring partial echoes during the idle wait times present in ETS. Using the proposed technique, higher resolution images are acquired when total scan time is fixed. Alternately, shorter scan times are possible when the in-plane resolution is fixed. Equations that predict the expected improvement in resolution are derived and shown to be accurate through simulations and experiments. In vivo images obtained using conventional ETS and the proposed method show that the time savings obtained with the proposed method do not result in any visible degradation in image quality. Signal changes caused by cardiac pulsation and respiratory fluctuation are also a major confound in fMRI. These time-locked signal changes, also referred to as "physiological noise, " decrease the sensitivity of fMRI to neuronally-induced signal fluctuations. To date, no method exists that compensates for these detrimental effects in 3D fMRI acquisitions. This dissertation presents a novel algorithm that compensates for physiological noise in 3D echo-planar fMRI. The proposed method utilizes composite property mapping and efficient root-solving to estimate physiologically-induced signal fluctuations in 3D k-space data. These signal fluctuations are subsequently regressed from k-space data. Results show that the estimated signal fluctuations have significant power in the cardiac and respiratory frequency bands. Further, resting-state fMRI experiments show an increase in the number of activated voxels when the proposed compensation algorithm is employed. This is accompanied by an increase in the average z-score of activated voxels, and a more Gaussian distributed voxel time-course. In conclusion, this dissertation describes advances in data acquisition and post- processing in 3D fMRI that are easy to implement. Further, promising experimental results suggest the efficacy of all the proposed methods.
  • Digital
    editor, Harvey D. White.
    Future Med2012
    Advances in acute coronary syndrome management / Harvey White -- Etiology and overview / Ralph A.H. Stewart -- Biomarkers in acute coronary syndromes / Harvey D. White -- Clinical risk scores in ACS management : current and future directions / Derek P. Chew & Leong Lee -- Antithrombotic therapies / Paul A. Gurbel & Udaya S. Tantry -- Lipid-lowering therapy / Joel A. Lardizabal & Prakash C. Deedwania -- Antihypertensive therapies / Grégoire Wuerzner, Olivier Muller & Michel Burnier -- Interventional approaches to acute coronary syndromes / Neal S. Kleiman -- Noninvasive imaging in acute coronary syndromes / Govind Srinivasan & Joseph Selvanayagam -- Electrocardiography in acute coronary syndromes / Cheuk-Kit Wong & Harvey D. White -- Current guidelines for acute coronary syndromes / Michel E. Bertrand -- Index.
  • Digital
    guest editors, Neville H. Golden, Martin M. Fisher.
    AAP ebooks2018
  • Digital
    Abraham Fisher, Maurizio Memo, Fabrizio Stocchi, Israel Hanin, editors.
    Springer2008
    The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer's disease and Parkinson's disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume.
  • Digital
    editors, Serge Gauthier, Pedro Rosa-Neto.
    Future Med2012
    Advances in Alzheimer's disease management / Serge Gauthier & Pedro Rosa-Neto -- Genetics of Alzheimer's disease / Jayashree Viswanathan, Hilkka Soininen & Mikko Hiltunen -- Diagnosis of Alzheimer's disease / Pedro Rosa-Neto, Jared Rowley, Antoine Leuzy, Sara Mohades, Monica Shin, Marina T. Dauar & Serge Gauthier -- Available symptomatic antidementia drugs / Marie-Pierre Thibodeau & Fadi Massoud -- New drugs under development for Alzheimer's disease / Lezanne Ooi, Kirubakaran Shanmugam, Mili Patel, Rachel Debono & Gerald Münch -- Management of agitation and aggression : controversies and possible solutions / Clive Ballard & Anne Corbett -- Guidelines for the diagnosis and treatment of Alzheimer's disease / Serge Gauthier & Christopher J.S. Patterson -- Ethical and clinically humane end-of-life care for those living with dementia / Michael Gordon -- Index.
  • Digital
    editor, Denise Anne Moneret-Vautrin.
    Future Med2014
    Advances in anaphylaxis management / Denise Anne Moneret-Vautrin -- Anaphylaxis : classification and clinical symptoms / Johannes Ring, Jarmila Liptak & Knut Brockow -- Pathophysiology : IgE-mediated and non-IgE-mediated anaphylaxis / Denise Anne Moneret-Vautrin -- Risk factors for fatal anaphylaxis / Richard Pumphrey & Gunter Sturm -- Etiologies of anaphylaxis / Margitta Worm -- Biomarkers for the evaluation of severity of anaphylaxis / Julia Upton & Peter Vadas -- Role of specific IgE testing in allergy diagnosis / Sandrine Jacquenet, Denise-Anne Moneret-Vautrin & Bernard E. Bihain -- Treatment algorithm for anaphylaxis and prognosis / Ben Gibbison & Jasmeet Soar -- Food anaphylaxis prevention / Martine Morisset -- Hymenoptera anaphylaxis : indications and results of immunotherapy / Ulrich R. Müller & Arthur Helbling -- Index.
  • Digital/Print
    Digital : Springerv. 177-, 2005-
  • Digital
    editor, Philip N. Patsalos.
    Future Med2011
    Advances in antiepileptic drug development / Philip N. Patsalos -- Current guidelines and standard treatments / Dieter Schmidt & G{uml}unter Kr{uml}amer -- Advances in screening models for identifying new antiepileptic drugs / Kinga K. Borowicz & Stanislaw J. Czuczwar -- New antiepileptic drugs : advances in pharmacokinetics, drug interaction and adverse effect profiles / Domenico Italiano & Edoardo Spina -- Antiepileptic drugs in clinical trials and future direction / Alberto Verrotti, Chiara Cirillo & Giulia Loiacono.
  • Digital
    Akihito Yokoyama, editor.
    Springer2019
  • Digital
    edited by Roger Narayan, Paolo Colombo ; volume editors Michael Halbig, Sanjay Mathur.
    Wiley2013
  • Digital
    Dhalla, Naranjan S.
  • Digital
    editors, Yoshihiro Ito, RIKEN Institute, Wako-shi, Saitama, Japan, Xuesi Chen, Chinese Academy of Sciences, Changchun, Jilin, China, Inn-Kyu Kang, Kyungpook National University, Daegu, South Korea.
    Am Chem Socv. 1, 2017
    Am Chem Socv. 2, 2017
  • Digital
    edited by Nikhil C. Munshi, Kenneth C. Anderson.
    Springer2013
    Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.
  • Digital
    edited by Nikhil C. Munshi, Kenneth C. Anderson.
    Springer2013
    Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.
  • Digital
    Kumaravel Somasundaram, editor.
    Springer2017
    1. Maximal safe resection in glioblastoma: use of adjuncts -- 2. Molecular pathology of glioblastoma- an update -- 3. Current therapies and future directions in treatment of glioblastoma -- 4. Recent advances for targeted therapies in glioblastoma -- 5. Targeting EGFR in glioblastoma: molecular biology and current understanding -- 6. Radiogenomics and histomics in glioblastoma: the promise of linking image-derived phenotype with genomic information -- 7. Next-generation sequencing in glioblastoma personalized therapy -- 8. Glioma stem-like cells in tumor growth and therapy resistance of glioblastoma -- 9. Animal models in glioblastoma: use in biology and developing therapeutic strategies -- 10. Pediatric high grade glioma -- Index.
  • Print
    edited by David O. Cooney.
    Status: Not Checked Out
  • Digital
    Mieczyslaw Pokorski, editor.
    Springer2019
    This book gathers multidisciplinary articles that present advances of our understanding of diseases and the effective treatment of patients. The authors share recent clinical and experimental research findings, highlighting poorly understood areas with uncertain treatment outcomes, such as giant-cell bone tumors and their propensity to metastasize to the lungs; subterranean rehabilitation in pulmonary disorders; male reproductive hormone regulation during physical exercise in hyperbaric, hyperoxic environments, like underwater diving; and amelioration of cognitive decline owing to increased cerebral blood transit time after internal carotid artery stenting. Other topics include new concepts and innovations in the treatment of diabetes in pregnancy, and leg ulcers in chronic venous insufficiency, as well as molecular research on the toxic effects of oxidative stress, impaired cell autophagy, and experimental conditions resembling air pollution. Featuring the latest interdisciplinary advances in biomedicine, this book is a valuable resource for medical professionals, both academics and practitioners, and all allied health-care workers.
  • Digital
    editors, Piero Picci, Pietro Ruggieri.
    Future Med2012
    Advances in bone metastasis management / Piero Picci & Pietro Ruggieri -- Pathways to metastases : how do metastases develop in bone / Jeff Toreson & Robert E. Turcotte -- Metastatic spread to bone : the role of chemotherapy / Stefano Ferrari, Emanuela Palmerini, Andreas F. Mavrogenis & Pietro Ruggieri -- Bone stroma inhibition in prostate cancer / Michael A. Carducci & Daniel Keizman -- Management of bone metastases in breast cancer / Toni Ibrahim & Dino Amadori -- Radiotherapy for bone metastases / Julia Di Giovanni, Janet Nguyen, Marko Popovic & Edward Chow -- Bisphosphonates for bone metastases / Esther Chan & Urban Emmenegger -- Surgical treatment for spinal metastases / Roberto Casadei, Andreas F. Mavrogenis, Marco Manfrini & Pietro Ruggieri -- Surgical treatment for pelvic bone metastases / Andreas F Mavrogenis, Eugenio Brunocilla, Giuseppe Bianchi, Nicola Fabbri & Pietro Ruggieri -- Surgical treatment for metastatic pathological fractures / Andreas F. Mavrogenis, Roberto Casadei & Pietro Ruggieri -- Palliative treatments : selective arterial embolization for bone metastases / Giuseppe Rossi, Andreas F. Mavrogenis, Piero Picci & Pietro Ruggieri -- Palliative treatments : electrochemotherapy and thermoablation / Giuseppe Bianchi, Laura Campanacci, Eugenio Rimondi & Pietro Ruggieri -- Novel targeted therapies of bone tumors and future directions / Dominique Heymann -- Index.
  • Digital/Print
    edited by William J. Gradishar and William C. Wood.
    Digital : Springer2008
    Print2008
  • Digital
    Rebecca Rakow-Penner.
    Breast magnetic resonance imaging (MRI) is becoming an increasingly valuable technology for breast cancer detection, especially for women at high risk for the disease. Stanford Hospital alone performed approximately 1,000 breast MRIs last year. This demand and need to increase specificity of breast MRI motivates improving current breast MR protocols, as well as exploring new applications of MR technology to breast imaging. Most clinical breast MR exams are performed at a 1.5T field strength. 3T scanners, however, are becoming more prevalent in the clinical setting and thus the breast MR protocol needs to be tuned accordingly. The first project includes measurements of T1 and T2 of breast fat and glandular tissue at 1.5T and 3T and the corresponding recommendation for altering the TR and TE for 3T breast imaging. The beating heart posterior to the breast often produces artifacts in breast MR images. The second project is a cylindrical saturation method that reduces unwanted signal from the heart while avoiding signal loss from the breast tissue of interest. Detecting tumor oxygenation non-invasively may give insight on tumor differentiation, predict susceptibility to antiangiogenic therapeutics, and monitor chemotherapeutics. The third project introduces the application of BOLD contrast imaging, a technique usually applied in functional brain MR imaging for characterizing tumor oxygenation in the breast.
  • Digital/Print
    Roberto Scatena, editor.
    Digital : Springer2015
    Print2015
    "At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and "polluted" knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology. This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation"--Back cover.
  • Digital/Print
    Greenstein, Jesse P.; Haddow, Alexander; Klein, George; Weinhouse, Sidney.
    Digital : ScienceDirectv. 1-, 1953-
  • Digital
    Roberto Scatena, Alvaro Mordente, Bruno Giardina, editors.
    Springer2012
    1. Cancer Stem Cells: A Revisitation of the "Anaplasia" Concept / Roberto Scatena -- 2. Stem Cells and Cancer Stem Cells: New Insights / Toru Kondo -- 3. Molecular Biology of Cancer Stem Cells / Oswaldo Keith Okamoto -- 4. Biomarkers of Cancer Stem Cells / Jun Dou and Ning Gu -- 5. Cancer Stem Cells and the Microenvironment / Alfonso Colombatti, Carla Danussi, Eliana Pivetta, and Paola Spessotto -- 6. Leukemia Stem Cells / Steven W. Lane and David A. Williams -- 7. Cancer Stem Cells and the Central Nervous System / Serdar Korur, Maria Maddalena Lino, and Adrian Merlo -- 8. Cancer Stem Cells and Glioblastoma Multiforme: Pathophysiological and Clinical Aspects / Akio Soeda, Mark E. Shaffrey, and Deric M. Park -- 9. Breast Cancer Stem Cells / Nuria Rodríguez Salas, Enrique González González, and Carlos Gamallo Amat -- 10. Colon Cancer Stem Cells / Ugo Testa -- 11. Liver Tumor-Initiating Cells/Cancer Stem Cells: Past Studies, Current Status, and Future Perspectives / Kwan Ho Tang, Stephanie Ma, and Xin-Yuan Guan -- 12. Pancreatic Cancer Stem Cells / Erica N. Proctor and Diane M. Simeone -- 13. Cancer Stem Cells and Renal Carcinoma / Benedetta Bussolati and Giovanni Camussi -- 14. Cancer Stem Cells: Proteomic Approaches for New Potential Diagnostic and Prognostic Biomarkers / Patrizia Bottoni, Bruno Giardina, and Roberto Scatena -- 15. Cancer Stem Cells: An Innovative Therapeutic Approach / Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio, Salvatore Scarà, and Bruno Giardina -- 16. Cancer Stem Cell and ATP-Binding Cassette: Which Role in Chemoresistance? / Andrea Silvestrini, Elisabetta Meucci, Giuseppe Ettore Martorana, Bruno Giardina, and Alvaro Mordente -- 17. Stem Cells and Cancer Stem Cells: Biological and Clinical Interrelationships / Cinzia Bagalà and Carlo Barone -- 18. Immunomodulatory Functions of Cancer Stem Cells / Tobias Schatton, Jennifer Y. Lin, and Markus H. Frank.
  • Digital
    Lewis E. Foxhall, Maria Alma Rodriguez, editors.
    Springer2015
    This volume presents the MD Anderson experience in providing care and services to the rapidly growing population of cancer survivors, which is currently estimated to be 12 million in the United States and more than 25 million worldwide. As cancer survival rates have increased, it has slowly become clear that the challenges faced by people with cancer do not end with treatment but simply change. This book aims to assist community oncologists, physicians, and their staff, who care for the vast majority of cancer survivors, by disseminating models of surveillance for disease recurrence, screening for second primary cancers, education regarding potential late effects of treatment, and psychosocial counseling. These models have proven valuable to cancer survivors who receive care at MD Anderson.
  • Digital
    Pongali Raghavendra, Thammineni Pullaiah.
    ScienceDirect2018
    Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare.
  • Digital/Print
    Sami Malek, editor.
    Digital : Springer2013
    Print2013
    Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. CLL has a highly varied clinical course. While advances in CLL therapy are noted, many patients still succumb to this illness. Like most progress in medicine, solid advances in the diagnosis, prognosis and treatment of CLL are rooted in an in-depth understanding of the basic and translational biology of CLL. In this book, CLL experts have contributed state-of-the-art summaries of various important aspects of CLL biology and have discussed the translational implication of such findings. This book, which is directed at physicians and researchers alike, aims to educate broadly and deeply. Intentionally, the many aspects and nuances of CLL clinical care that can only really be appreciated through direct patient care are not covered here, but instead, the book presents basic aspects of CLL that underlie many of the contemporary decisions that are made in CLL research and clinical settings. We hope that this book will critically inform the community and stimulate interest in CLL, which will ultimately translate into better CLL research, prognostication and therapy, with the end goal of providing a better outlook for patients afflicted with this common leukemia.
  • Digital/Print
    Mieczyslaw Pokorski, editor.
    Digital : Springer2016
    Print2016
    Prevalence of olfactory impairment in granulomatosis with polyangiitis -- Biochemistry of oxidative stress -- Usage of over-the-counter and herbal products in common cold in Poland: findings from consumer survey -- RARβ promoter methylation as an epigenetic mechanism of gene silencing in non-small cell lung cancer -- Cardiovascular risk factors in obese children and adolescents -- Nutrition and immune system in children with simple obesity -- The influence of shockwave therapy on orthodontic tooth movement induced in the rat -- Thyroid hormone levels and TSH activity in patients with obstructive sleep apnea syndrome -- Age and gender-related changes in biogenic amine metabolites in cerebrospinal fluid in children -- The influence of primary cytomegalovirus or Epstein-Barr virus infection on the course of idiopathic thrombocytopenic purpura -- Index.
  • Digital
    Rubin Wang, Fanji Gu, editors.
    Springer2011
    Within our knowledge, the series of the International Conference on Cognitive Neurodynamics (ICCN) is the only conference series dedicating to cognitive neurodynamics. This volume is the proceedings of the 2nd International Conference on Cognitive Neurodynamics held in 2009, which reviews the progress in this field since the 1st ICCN -2007. The topics include: Neural coding and realistic neural network dynamics, Neural population dynamics, Firing Oscillations and Patterns in Neuronal Networks, Brain imaging, EEG, MEG, Sensory and Motor Dynamics, Global cognitive function, Multi-scalar Neurodyn
  • Digital
    Yoko Yamaguchi, editor.
    Springer2013
    This book contains the Proceedings of the 3rd International Conference on Cognitive Neurodynamics held in Japan, June 9-13, 2011. It reviews the progress in this field since the first ICCN in 2007. The participants were treated to an exciting and stimulating conference that left everyone with an enthusiastic vision for the future. The discussed topics in this book include: Neural coding and realistic neural network dynamics, Neural population dynamics, Firing Oscillations and Patterns in Neuronal Networks, Brain imaging, EEG, MEG, Sensory and Motor Dynamics, Global cognitive function, Multi-scalar Neurodynamics - from Physiology to Systems Theory, Neural computing, Emerging Technologies for Brain Computer Interfaces, Neural dynamics of brain disorders.
  • Digital
    Jerome D. Williams, Keryn E. Pasch, Chiquita A. Collins, editors.
    Springer2013
    Overview, The IOM Report, and Integrated Marketing Communications -- Introduction: Childhood Obesity: Media, Advertising, Community, and Advocacy -- Progress on Public Policy: The Aftermath of the 2005 Institute of Medicine Report on Food Marketing and the Diets of Children and Youth -- Integrated Marketing Communications and Power Imbalance: The Strategic Nature of Marketing to Children and Adolescents by Food and Beverage Companies -- Legal, Ethical, and Policy Implications of Advertising -- The Role of Ethics in Food and Beverage Marketing to Children -- The New First Amendment and Its Implications for Combating Obesity Through Regulation of Advertising -- Self-regulation as a Tool for Promoting Healthier Children's Diets: Can CARU and the CFBAI Do More? -- Monitoring Food Company Marketing to Children to Spotlight Best and Worst Practices -- Measuring the Impact of Advertising Effects -- Children's Exposure to Food and Beverage Advertising on Television: Tracking Calories and Nutritional Content by Company Membership in Self-regulation -- The Role of Advertising on Attitudes and Consumption of Food and Beverage Products -- The Digital Food Marketing Landscape: Challenges for Researchers -- A Multi-Method Study to Understand How Youth Perceive and Evaluate Food and Beverage Advertisements -- A Global Perspective of Food Marketing and the Role of Place -- Adolescents' Response to Food Marketing in Delhi, India -- The Role of Schools in Food and Beverage Marketing: Significance, Challenges, Next Steps -- Outdoor Food and Beverage Advertising: A Saturated Environment -- Exploring Marketing Targeted at Youth in Food Stores -- Racial/Ethnic Minorities and Community Empowerment -- Understanding Community Perspectives: A Step Towards Achieving Food Marketing Equity -- Latino Youth and Obesity: Communication/Media Influence on Marketing -- Targeted Marketing of Junk Food to Ethnic Minority Youth: Fighting Back with Legal Advocacy and Community Engagement -- Communicating About Physical Activity -- Physical Activity, Media, and Marketing: Advances in Communications and Media Marketing -- Communities Leveraging the Assets of a National Social Marketing Campaign: Experiences with VERB[TM]. It's What You Do! -- Development and Release of the 2008 Physical Activity Guidelines for Americans: Children and Adolescents -- Thinking Outside the Box: Finding Solutions to Reverse Childhood Obesity -- Voluntary Health Organizations and Nonprofit Advocacy Organizations Play Critical Roles in Making Community Norms More Supportive of Healthier Eating and Increased Physical Activity -- Childhood Obesity and Exergames: Assessments and Experiences from Singapore -- Leveraging Industry Efforts to Fight Childhood Obesity: A Multi-Sectored Approach to Communications.
  • Digital/Print
    Hamid R. Arabnia, editor.
    Digital : Springer2010
    Print2010
    Bioinformatics databases, data mining, and pattern discovery -- Microarray, gene expression analysis, and gene regulatory networks -- Protein classification & structure prediction, and computational structural biology -- Comparative sequence, genome analysis, genome assembly, and genome scale computational methods -- Drug design, drug screening, and related topics -- Computational methods and diagnostic tools in biomedical -- General topics in bioinformatics.
  • Digital
    Justin Daniel Smith.
    This thesis is organized into two primary areas of research: cis-regulatory evolution and genome engineering. It is now known that noncoding regions comprise the vast majority of genomic regions under selective constraint in mammals. Despite this, the ability to detect natural selection on noncoding regions has lagged behind the ability to detect selection on coding regions. In Chapter 1, we introduce a new test to detect selection on cis-regulatory elements, and demonstrate its utility on three mammalian transcriptional enhancers. In Chapter 2, we investigate the evolution of resistance to the mycotoxin citrinin by comparing two closely related species of budding yeast, Saccharomyces paradoxus and Saccharomyces cerevisiae. Applying a genome-wide test for selection on cis-regulation, we identified five genes involved in resistance in S paradoxus, four of which are necessary for resistance and increase resistance in S cerevisiae when over-expressed. In the second half of this dissertation, I discuss my work with genome engineering and CRISPR-Cas9. In Chapter 2, we build an improved CRISPR activator (CRISPRa) to simultaneously induce overexpression (in S cerevisiae) of the four genes identified to confirm their role in citrinin resistance. In Chapter 3, we build an inducible CRISPR interference (CRISPRi) system and and designed gRNA libraries to determine design rules for CRISPRi gRNA design in S cerevisiae. We determined that gRNAs targeted to a region with low nucleosome occupancy and high chromatin accessibility within a window of 0 to 200bp upstream of the transcription start site (TSS) are most likely to be effective. In Chapter 4 we confirm and refine these rules in a much larger library consisting of ~9000 unique strains. Additionally, we present a novel method for parsing complex oligonucleotide libraries into single, sequence verified DNA sequences using high throughput sequencing and yeast synthetic biology. We utilize this technology to create and characterize a collection of ~9000 individual inducible CRISPRi strains to the vast majority of essential and respiratory essential genes in S cerevisiae. In Chapter 5, we compare mismatch tolerance for Cas9 in vitro and in vivo (in S cerevisiae) and test a variety of truncated and full-length gRNAs (with 17, 18, and 20 nucleotides of complementarity sequence). We observed notable differences between in vitro and in vivo Cas9 cleavage specificity profiles, with in vivo cleavage being more sensitive/less tolerant to mismatches.
  • Digital
    Samir A. Farghaly, editor.
    Springer2014
    This volume is an up-to-date resource on the international state-of-the-art in the diagnosis and management of ovarian cancer. While this devastating disease has been considered mainly a disease of the Western hemisphere, the book moves beyond our conventional understanding and embraces knowledge from around the world. It focuses on recent advances in diagnosis, including genetic screening; improvements and expanded choices in management, such as gene therapy and the optimization of chemotherapeutic agents; and the latest laparoscopic and robotic surgical techniques. Further chapters address histopathologic features of this disease, and related psychosocial and quality of-life-issues. The book is aimed at the wide range of practitioners who care for patients with ovarian cancer and researchers who study the disease: general surgeons, surgical oncologists, gynecological oncologists, medical oncologists, pediatric oncologists, gynecological pathologists, gynecologists, gynecological cancer epidemiologists, gynecological onco-psychologist, genetic counselors, geneticists, and cancer research scientists.
  • Digital
    Lawrence Panasci, Raquel Aloyz, Moulay Alaoui-Jamali, editors.
    Springer2013
    Repair of DNA Interstrand Cross-links Produced by Cancer Chemotherapeutic Drugs / Anderson T. Wang, Peter J. McHugh -- DNA-PK, a Pharmacological Target in Cancer Chemotherapy and Radiotherapy? / Bernard Salles D.V.M., Ph.D. -- Growth Factor Receptor Signaling, DNA Damage Response, and Cancer Cell Susceptibility to Chemotherapy and Relapses / Moulay Alaoui-Jamali, Amine Saad, Gerald Batist -- The Relationship Between DNA-Repair Genes, Cellular Radiosensitivity, and the Response of Tumors and Normal Tissues to Radiotherapy / David Murray, Matthew Parliament -- Important Roles of ERCC1 in DNA Repair and Targeted Therapy / Jennifer J. Hu, Joseph de la Garza -- The Role of BRCA1 and BRCA2 in Anticancer Drug Therapy / Andrew Y. Shuen, Jorge S. Reis-Filho -- DNA-PK in CLL Chemotherapy / L. Amrein, D. Davidson, R. Aloyz, L. Panasci -- Poly(ADP) Ribose Polymerase at the Interface of DNA Damage Signaling and DNA Repair / Jana Krietsch, Michele Rouleau, Michel Lebel -- Cellular Protection Against the Antitumor Drug Bleomycin / Dindial Ramotar Ph.D., Mustapha Aouida Ph.D. -- ATR as a Therapeutic Target / Fiona K. Middleton, Nicola J. Curtin -- Telomeres, Telomerase, and DNA Damage Response in Cancer Therapy / Raina A. Tamakawa, Helen B. Fleisig -- RAD51 Is a Key Protein of DNA Repair and Homologous Recombination in Humans / Alexander V. Mazin Ph.D., Olga M. Mazina.
  • Digital
    editor, Wilbert S. Aronow.
    Future Med2014
    Advances in dyslipidemia / Wilbert S. Aronow -- Atherosclerosis : dyslipidemia, inflammation and lipoapoptosis / Fleur M. van der Valk, Dominik M. Schulte, Willem J.M. Mulder & Erik S.G. Stroes -- Familial hypercholesterolemia : bridging and minding the gap in healthcare / Jing Pang, Alistair W. Vickery & Gerald F. Watts -- PCSK9 inhibition : drug development for low-density lipoprotein lowering / Geetha Mukerji, Rawand M. Abdin & Dominic S. Ng -- Novel therapies for dyslipidemia / Anthony S. Wierzbicki -- The highs and lows of high-density lipoprotein / Daniel Soffer & Marisa Schoen -- Do we need to treat patients with heart failure with statins? / Sadip Pant, Guru S. Gurumurthy, Abhishek Deshmukh & Jawahar L. Mehta -- Management of dyslipidemia in patients with nonalcoholic fatty liver disease / Konstantinos Tziomalos, Vasilios G. Athyros & Asterios Karagiannis -- Dyslipidemia : current management and the challenge of residual cardiovascular risk reduction / Aaron Rockoff, Vaijinath S. Kamanna & Moti L. Kashyap -- Index.
  • Print
    by J.A. Abildskov ... [et al.] ; edited by Robert C. Schlant and J. Willis Hurst.
    Status: Not Checked Out
  • Digital
    Vijay C. Verma, Alan C. Gange, editors.
    Springer2014
    In recent years there has been significant attention paid on the endophytic research by various groups working within this domain. Mutualistic endophytic microbes with an emphasis on the relatively understudied fungal endophytes are the focus of this special book. Plants are associated with micro-organisms: endophytic bacteria and fungi, which live inter- and intra-cellularly without inducing pathogenic symptoms, but have active biochemical and genetic interactions with their host. Endophytes play vital roles as plant growth promoters, biocontrol agents, biosurfactant producers, enzymes and secondary metabolite producers, as well as providing a new hidden repertoire of bioactive natural products with uses in pharmaceutical, agrochemical and other biotechnological applications. The increasing interest in endophytic research generates significant progress in our understanding of the host-endophyte relationship at molecular and genetic level. The bio-prospection of microbial endophytes has led to exciting possibilities for their biotechnological application as biocontrol agent, bioactive metabolites, and other useful traits. Apart from these virtues, the microbial endophytes may be adapted to the complex metabolism of many desired molecules that can be of significant industrial applications. These microbes can be a useful alternative for sustainable solutions for ecological control of pests and diseases, and can reduce the burden of excess of chemical fertilizers for this purpose. This book is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.
  • Digital
    Toshifumi Hibi, Tadakazu Hisamatsu, Taku Kobayashi, editors.
    Springer2018
    Part 1 The role of endoscopy in IBD -- Chapter 1 The Role of Endoscopy in IBD -- Chapter 2 Current progress of endoscopy in IBD: Colonoscopy -- Chapter 3 Current progress of endoscopy in IBD: Balloon enteroscopy -- Chapter 4 Current progress of endoscopy in IBD: Capsule endoscopy -- Chapter 5 Current progress of endoscopy in IBD: CT enterography and CT colonography in IBD -- Chapter 6 Current progress of endoscopy in IBD: MR Enterography -- Part 2 Endoscopic diagnosis of IBD -- Chapter 7 Diagnosis of UC-typical findings and diagnostic criteria -- Chapter 8 Typical Endoscopic Findings and Diagnostic Criteria for Crohn's Disease -- Chapter 9 Differential diagnosis of IBD: Endoscopic findings and diagnosis of intestinal Behçet's disease and simple ulcer syndrome -- Chapter 10 Differential diagnosis of Inflammatory Bowel Disease: Endoscopic findings and diagnosis of intestinal tuberculosis -- Chapter 11 Endoscopic findings and diagnosis of other inflammatory bowel diseases of lower GI tract -- Chapter 12 Endoscopic findings and Diagnosis of other inflammatory diseases of lower GI tract (except for infectious): vascular, eosinophilic, inflammation associated with other diseases etc -- Chapter 13 Endoscopic findings and Diagnosis of infectious diseases of lower GI tract: bacterial, pseudomembraneous, amoebic colitis CMV -- Chapter 14 Difficulty in diagnosing IBD: a case study -- Part 3: Endoscopy in the management of IBD -- Chapter 15 Endoscopy in the Management of Inflammatory Bowel Disease: Who, When, and How -- Chapter 16 Endoscopic index in UC -- Chapter 17 Endoscopic score in Crohn's disease -- Chapter 18 Mucosal healing in UC -- Chapter 19 The efficacies and issues for endoscopic assessment of mucosal healing in patients with Crohn's disease -- Chapter 20 Endoscopic intervention in IBD -- Chapter 21 Surveillance colonoscopy -- Chapter 22 Surveillance colonoscopy (Cases of small intestinal cancers in CD, Cases of anal cancers in CD) -- Part 4: Endoscopy in IBD- international differences -- Chapter 23 Endoscopy in Inflammatory Bowel Disease: Asian perspectives with respect to Japan -- Chapter 24 Endoscopy in IBD: Asian Perspective: Korea -- Chapter 25 Endoscopy in Chinese IBD patients: similarities and differences to the Western world -- Chapter 26 Endoscopy in IBD: A South Asian perspective from India -- Chapter 27 Endoscopy in IBD: Asian Perspective: Singapore -- Chapter 28 Endoscopy in IBD: Western perspectives: North America -- Chapter 29 Endoscopy in IBD: Western Perspective: Europe.
  • Digital
    Pratyoosh Shukla, Brett I. Pletschke, editors.
    Springer2013
    Improvement of thermostable enzyme with sugar metabolic activity by targeted mutagenesis -- Glycoside hydrolases for modification of glycosylation in polyphenolic antioxidants -- On the enzyme specificity for the synthesis of prebiotic galacto-oligosaccharides -- Microbial mannanases: properties and applications -- Enzyme Synergy for Enhanced Degradation of Lignocellulosic Waste -- Manganese peroxidase: molecular diversity, heterologous expression and applications -- Advance Techniques in Enzyme Research -- Regulatory motif identification in biological sequences: An overview of computational methodologies -- Structural, Molecular and Functional Aspects of Chitin deacetylase -- Role of enzymes and proteins in plant -- microbe interaction : A study of M. oryzae vs Rice -- Industrial enzyme applications in biorefineries for starchy materials.
  • Digital/Print
  • Digital
    Springerv. 1-, 2017-
  • Digital
    Donelli, Gianfranco.
    Springerv. 1-, 2016-
  • Digital/Print
    edited by Lubo Zhang, Charles A. Ducsay.
    Digital : Springer2014
    Print2014
    "To celebrate the Center for Perinatal Biology's 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease"--Publisher's description.
  • Digital
    Stefan Engeser, editor.
    Springer2012
  • Digital
    Guo-Liang Wang, Barbara Valent, editors.
    Springer2009
  • Digital/Print
    Anne Lynn S. Chang, editor.
    Digital : Springer2015
    Print2015
    This concise, easy-to-read book summarizes the current clinical evidence and basic science relating to aging and the skin, assisting the clinician in addressing skin problems in older dermatologic patients. Each chapter focuses on a particular area in which new knowledge has rapidly emerged over the past 5 years, ensuring that the book is completely up-to-date. Recent insights into aging skin from basic and translational science are first discussed, covering the underlying genetics and the potential role of topical agents and procedures in reversing the aging process. Evidence-based prescribing in older patients is then explained, and the evidence relating to treatments for psoriasis, reviewed. Further chapters in Geriatric Dermatology address non-surgical treatment options for basal cell carcinoma, the increase in and management of sexually transmitted diseases in older dermatology patients, and cutaneous signs of elder mistreatment. Case vignettes and informative illustrations assist the reader in quickly grasping the connection between an age-related process and its clinical impact. Geriatric Dermatology is written for dermatologists, research scientists with translational interest, geriatricians, and gerontologists.
  • Digital
    Felipe Sierra, Ronald Kohanski, editors.
    Springer2016
    The Geroscience Hypothesis: Is It Possible to Change the Rate of Aging? / Steven N. Austad -- Etiological Role of Aging in Chronic Diseases: From Epidemiological Evidence to the New Geroscience / Linda P. Fried and Luigi Ferrucci -- The Impact of Aging on Cancer Progression and Treatment / Shenghui He and Norman E. Sharpless -- The Impact of Cancer Treatments on Aging / Changhan Lee and Valter Longo -- Cardiovascular Disease and Aging / Ying Ann Chiao, Edward Lakatta, Zoltan Ungvari, Dao-Fu Dai and Peter Rabinovitch -- The Impact of Aging on Ischemic Stroke / Farida Sohrabji -- Parkinson's Disease and Aging / Julie K. Andersen -- The Role of Aging in Alzheimer's Disease / Geoffrey A. Kerchner and Tony Wyss-Coray -- Aging and the Bone-Muscle Interface / Simon Melov and Clifford J. Rosen -- Osteoporosis and Mechanisms of Skeletal Aging / Julie Glowacki and Tamara Vokes -- Osteoarthritis in the Elderly / Richard F. Loeser and Martin Lotz -- Diabetes and Aging / Nicolas Musi and Andrzej Bartke -- Renal Aging and Transplantation / John P. Higgins and Stuart K. Kim -- Asthma and Aging / Nicola A. Hanania and Paula Busse -- Aging in COPD and Idiopathic Pulmonary Fibrosis / Cecilia Sanchez -- Age-Related Macular Degeneration and Vision Impairment / Jayakrishna Ambati and Charles Wright -- HIV and Aging: Parallels and Synergistic Mechanisms Leading to Premature Disease and Functional Decline / Anna Hearps, Katherine Schafer, Kevin High and Alan Landay -- Pain in the Elderly / Roger B. Fillingim, Dennis C. Turk and Robert P. Yezierski -- The Way Forward: Translation / James L. Kirkland.
  • Digital
    guest editors, Alwyn Cohall and Michael Resnick.
    eBook Comp Acad2011
    Adolescent Medicine: State of the Art Reviews is the official journal of the AAP Section on Adolescent Health Care. This volume highlights achievements in adolescent health research and practice that are advancing the state of the art. These researchers are taking advantage of a vulnerable period in the lifespan and wisely using it as a time to promote public health. The literature collected here shares the insight of a broad range of professionals throughout the country ready to advise policy-makers and practitioners on how to build a healthy society. Topic.
  • Digital
    volume editors, Simon K.W. Lloyd, Neil Donnelly.
    Karger2018
    New imaging modalities in otology / Bance, M., Zarowski, A., Adamson, R.A., Casselman, J.W. -- Optimizing ossicular prosthesis design and placement / Bance, M. -- Advances in the field of bone conduction hearing implants / McLeod, R.W.J., Culling, J.F., Jiang, D. -- Hearing rehabilitation in congenital middle ear malformation / Frenzel, H. -- Hearing rehabilitation with active middle ear implants / Donnelly, N., Pennings, R.J.E. -- Brain plasticity and rehabilitation with a cochlear implant / McKay, C.M. -- Hearing preservation cochlear implant surgery / Bruce, I.A., Todt, I. -- Extended applications for cochlear implantation / Hempel, J.M., Simon, F., Müller, J.M. -- Management of cochlear nerve hypoplasia and aplasia / Freeman, S.R., Sennaroglu, L. -- Hearing rehabilitation in neurofibromatosis type 2 / North, H.J.D., Lloyd, S.K.W. -- The future of cochlear implant design / Mitchell-Innes, A., Saeed, S.R., Irving, R. -- Pharmacological issues in hearing rehabilitation / Bird, P.A., Bergin, M.J. -- Intraoperative auditory system monitoring / Miyazaki, H., Caye-Thomasen, P. -- Diagnosis and treatment of perilymphatic fistula / Deveze, A., Matsuda, H., Elziere, M., Ikezono, T. -- The role of the eustachian tube in middle ear disease / Tysome, J.R., Sudhoff, H.
  • Print
    edited by Dean T. Mason.
    Status: Not Checked Out
  • Digital
    editors, Henry Krum & Thomas von Lueder.
    Future Med2012
    Advances in heart failure management / Henry Krum & Thomas von Lueder -- Etiology and overview of heart failure / Yee Weng Wong & G. Michael Felker -- Pathophysiology and clinical manifestation / Thomas G. von Lueder & Dan Atar -- Imaging in heart failure / Sebastian Imre Sarvari & Thor Edvardsen -- Drug therapies for heart failure / Kaushik Guha & Theresa A. McDonagh -- Biomarkers in heart failure / Ashraf Mostafa, Mohamed El-Haddad & Jalal K. Ghali -- Atrial fibrillation in heart failure / Wanwarang Wongcharoen & Shih-Ann Chen -- Device therapy in heart failure / Evaldas Giedrimas & Bradley P. Knight -- Acute heart failure / Wolfgang Krûger -- Pediatric heart failure and adult congenital heart disease / Michael L. O'Byrne & Robert E. Shaddy -- Ventricular assist devices and heart transplantation / Jignesh Patel & Jaime D. Moriguchi -- Gene therapy / Henrike Tscheschner, Patrick Most & Philip Raake -- End-of-life care / Patricia M. Davidson & Phillip J. Newton -- Heart failure guidelines : translation into clinical practice / Nigel T. Lewis, Shanmugakumar Chinnappa, Gerald Partridge & Lip-Bun Tan.
  • Digital
    Eric O. Freed, editor.
    Springer2013
    Over the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle. This has been made possible by major advances in cell biology, virology, and structural biology. The field continues to move forward rapidly, with important new discoveries being reported on a regular basis. The impact of this progress across a broad spectrum of biomedical research has been substantial. The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research. The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.
  • Digital
    J. Marshall Clark, editor ; Jeffrey R. Bloomquist, editor ; Hitoshi Kawsada, editor ; sponsored by the ACS AGRO Division, Pesticide Science Society of Japan.
    Am Chem Soc2009
    Vector biology diagnostics and public health pesticides development through the product development partnership route / Janet Hemingway -- Pyrethroid resistance in the African malaria vector, Anopheles gambiae, and potential of alternative insecticides for indoor residual spraying and use on mosquito nets / Mark Rowland and Raphael N'Guessan -- Insecticide resistance in the mosquito Culex pipiens complex : concerns about development of pyrethroid resistance / Osamu Komagata, Shinji Kasai, and Takashi Tomita -- Vector control for prevention of dengue : current status and future strategies / Tessa B. Knox and Thomas W. Scott -- Current status and challenges of Chagas disease control initiatives in the Americas / Jun Nakagawa -- Human head lice : status, control, and resistance / J. Marshall Clark ... et al. -- ABC's of indoor health : allergens, baits, and cockroach mitigation strategies / Coby Schal -- Current status of house dust mites in Japan and prospects for control agents / Tomoyuki Hashimoto -- Controlling dengue virus transmission in the field with genetically modified mosquitoes / Ken E. Olson and Alexander W.E. Franz -- Pharmacological mapping of the acetylcholinesterase catalytic gorge in mosquitoes with bis(n)-tacrines / Troy D. Anderson ... et al. -- Olyset net : a long lasting insecticidal net for vector control / Takaaki Itoh ... [et al.] -- Biological efficacy of metofluthrin, a new pyrethroid insecticide, highly effective against mosquitoes / Takao Ishiwatari ... et al. -- An inconvenient truth of pyrethroids-do they have a promising future? / Hitoshi Kawada -- The body louse, Pediculus humanus humanus (Phthiraptera : Pediculidae), genome project : past, present, and opportunities for the futures / Barry R. Pittendrigh ... et al. -- Resistance management of the human head louse using molecular tools / Si Hyeock Lee ... et al. -- Monitoring of kdr-mediated pyrethroid resistance in head louse colonies in Japan / Shinji Kasai ... et al.
  • Digital
    Joseph C. Liao, Li-Ming Su, editors.
    Springer2015
    This book provides an overview of the current state-of-art in combining advances in biomedical imaging with intraoperative navigation and preoperative planning for urologic surgery. These advances hold great promise in improving diagnostic and therapeutic urologic interventions to improve patient outcomes. Leading experts in this exciting emerging field covers early clinical and pre-clinical applications of optical, ultrasound, cross-sectional, and computer-assisted imaging in urologic surgery. Advances in Image-Guided Urologic Surgery provides a unique and valuable resource for audience with clinical and research interest in minimally invasive surgery, endourology, urologic oncology, imaging, and biomedical engineering.
  • Digital
    Juan Manuel Suarez Grau, Juan Antonio Bellido Luque, editors.
    Springer2014
    With an increase in the use of laparoscopic techniques for the treatment of abdominal wall hernias, this comprehensive book provides a detailed description of the most up-to-date techniques used in the laparoscopic repair of inguinal and ventral incisional hernias. Advances in Laparoscopy of the Abdominal Wall Hernia takes the reader step-by-step through two laparoscopic techniques used in inguinal hernia correction: Extraperitoneal (TEP) and Transabdominal (TAPP), and guides the reader through the fundamentals of ventral hernia repair. The authors aim to show methods of dealing with rarer hernias and those of atypical location. This book will also inform the reader of the various kinds of meshes used and provides knowledge on how to fix them, as well as the advantages, disadvantages and indications of this type of prosthesis. Written by experts in the field, Advances in Laparoscopy of the Abdominal Wall Hernia is a valuable reference tool to surgeons and medical practitioners working in this field.
  • Digital
    edited by Deepak Gaur, Chetan E. Chitnis, Virander S. Chauhan.
    Wiley2017
    Introduction & overview of malaria and plasmodium / Virander S. Chauhan, Chetan E. Chitnis, Deepak Gaur -- Exoerythrocytic development of plasmodium parasites / Volker T. Heussler, Annika Rennenberg, and Rebecca R. Stanway -- Molecular basis of erythrocyte invasion by plasmodium merozoites / Deepak Gaur, Chetan E. Chitnis, Virander S. Chauhan -- The biology of malaria transmission / Robert E. Sinden -- Comparative and functional genomics of malaria parasites / Martine M. Zilversmit, Sittiporn Pattaradilokrat, and Xin-zhuan Su -- Gene regulation : new insights and possible intervention strategies / Artur Scherf, Nicholas A. Malmquist, Rafael M. Martins, Shruthi S. Vembar, and Jose-Juan Lopez-Rubio -- Molecular genetic approaches to malaria research / Brendan Elsworth, Mauro F. Azevedo, Brendan S. Crabb, and Paul R. Gilson -- Transcriptomics and proteomics / Archna P. Gupta, Zbynek Bozdech, and Peter R. Preiser -- The biochemistry of plasmodium falciparum : an updated overview / Hagai Ginsburg -- Signaling in malaria parasites / Pushkar Sharma, and Sudhir Kumar -- Membrane transport proteins as therapeutic targets in malaria / Sanjay A. Desai, Kempaiah Rayavara, Paresh Sharma, Sayeed K. Syed, Wang Nguitragool, and Praveen Balabaskaran Nina -- The proteolytic repertoire of malaria parasites / Puran Singh Sijwali, and Philip J. Rosenthal -- Development of medicines for the control and elimination of malaria / Jeremy N. Burrows, and Timothy N.C. Wells -- Antimalarial drug resistance / Naman K. Shah, and Neena Valecha -- Epidemiology of plasmodium falciparum malaria / Alberto L. García-Basteiro, Quique Bassat, and Pedro L. Alonso -- Malaria pathogenesis / Bronner P. Gonzalves, Michal Fried, and Patrick E. Duffy -- Host genetics / Thomas N. Williams -- The immune response in mild and severe malaria : two sides of the same coin / Michael Waisberg, Peter D. Crompton, Louis H. Miller, and Susan K. Pierce -- Progress in development of malaria vaccines / Chetan E. Chitnis, Deepak Gaur, and Virander S. Chauhan -- Plasmodium vivax : insights on burden and patho-biology / Ivo Mueller, Quique Bassat, Marcus V.G. Lacerda, and Hernando A. del Portillo.
  • Digital
    Bennie H. Jeng, editor.
    Springer2014
    This book presents up-to-date information on the diagnosis and management of the spectrum of medical and surgical corneal diseases, with a special focus on new technology. The latest tools for diagnosing ocular surface disease, infectious keratitis, and ocular allergies are discussed, along with novel treatment options for these entities. The impact of progress in imaging and contact lens technology on the management of corneal conditions is fully described, and the efficacy of corneal collagen crosslinking for keratoconus and corneal ectasia is evaluated. Detailed attention is devoted to the latest surgical techniques, including lamellar keratoplasty, endothelial keratoplasty, keratoprosthesis, and laser-assisted penetrating keratoplasty. In addition, the role of the eye bank in facilitating corneal procedures is explained. Advances in Medical and Surgical Cornea is written by leading authorities who share a passion for effective, cutting-edge care. It will be invaluable for both experienced ophthalmologists and trainees.
  • Digital
  • Digital
    edited by Mieczyslaw Pokorski.
    Springer2019
  • Digital/Print
    Gianfranco Donelli, editor.
    Digital : Springer2016
  • Digital/Print
    Gianfranco Donelli, editor.
    Digital : Springer2016
    Print2016
    Comparative evaluation of the antimicrobial activity of 19 essential oils / Naouel Chaftar, Marion Giradot, Jérôme Labanowski, Tawfik Ghrairi, Khaled Hani, Jacques Frère, and Christine Imbert -- Advances in microbiology, infectious diseases and public health: refractory Trichophyton rubrum infections in Turin, Italy: a problem still present / Vivian Tullio, Ornella Cervetti, Janira Roana, Michele Panzone, Daniela Scalas, Chiara Merlino, Valeria Allizond, Giuliana Banche Narcisa Mandras, and Anna Maria Cuffini -- Antioxidant hydroxytyrosol-based polyacrylate with antimicrobial and antiadhesive activity versus Staphylococcus epidermidis / Fernanda Crisante, Vincenzo Taresco, Gianfranco Donelli, Claudia Vuotto, Andrea Martinelli, Lucio D'Ilario, Loris Pietrelli, Iolanda Francolini, and Antonella Piozzi -- The role of human herpesvirus 8 in diabetes mellitus type 2: state of the art and a medical hypothesis / Raffaello Pompei -- Prevalence of Chlamydia trachomatis, Trichomonas vaginalis and Neisseria gonorrhoeae based on data collected by a network of clinical microbiology laboratories, in Italy / Maria Cristina Salfa, Barbara Suligoi and Italian STI Laboratory-based Surveillance Working Group -- [Beta]-defensins: work in progress / Giovanna Donnarumma, Iole Paoletti, Alessandra Fusco, Brunella Perfetto, Elisabetta Buommino, Vincenza de Gregorio, and Adone Baroni -- Emergence of Escherichia coli sequence type 131 (ST131) and ST3948 with KPC-2, KPC-3 and KPC-8 carbapenemases from a long-term care and rehabilitation facility (LTCRF) in northern Italy / Aurora Piazza, Mariasofia Caltagirone, Ibrahim Bitar, Elisabetta Nucleo, Melissa Spalla, Elena Fogato, Roberto D'Angelo, Laura Pagani, and Roberta Migliavacca -- Carbapenem-resistant Klebsiella pneumoniae: results of a laboratory surveillance program in an Italian general hospital (August 2014--January 2015) / Claudia Monari, Luca Merlini, Emanuela nardelli, Maria Cacioni, Antonella Repetto, Antonella Mencacci, and Anna Vecchiarelli -- A snapshot of drug-resistant M. tuberculosis strains in Croatia / Ljiljana Zmak, Mihaela Obrovac, and Vera Katalinic-Jankovic -- Quorum quenching strategy targeting gram-positive pathogenic bacteria / Ravindra Pal Singh, Said E. Desouky, and Jiro Nakayama.
  • Digital/Print
    Gianfranco Donelli, editor.
    Digital : Springer2016
    Print2016
    Biodiversity of intestinal lactic acid bacteria in the healthy population -- Clostridium difficile in food and animals: a comprehensive review -- Russian kefir grains microbial composition and its changes during production process.
  • Digital
    Gianfranco Donelli, editor.
    Springer2017
  • Digital
    Gianfranco Donelli, editor.
    Springer2018
    "This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention"--Publisher's description.
  • Digital/Print
    edited by Alberto Alexandre, Marcos Masini, Pier Maria Menchetti.
    Digital : Springer2011
    Print2011
    Surgical anatomy of the sacral hiatus for caudal access to the spinal canal -- Radiologic anatomy of the sacral canal -- Imaging in degenerative spine pathology -- Operative management of lumbar disc herniation: the evolution of knowledge and surgical techniques in the last century -- Philosophy and concepts of modern spine surgery -- Minimally invasive treatment for refractory low back pain, targeted by epidural endoscopy with O2/O3 and steroid therapy -- Epidural injections: past, present and future -- Long term intrathecal infusion of opiates for treatment of failed back surgery syndrome -- Modic changes: anatomy, pathophysiology and clinical correlation -- Periduroscopy: general review of clinical features and development of operative models -- The effectiveness of endoscopic epidurolysis in treatment of degenerative chronic low back pain: a prospective analysis and follow-up at 48 months -- Endoscopic approaches to the spinal cord -- Application of pulsed radio frequency to the dorsal horn and dorsal roots -- Automated nucleotomy and nucleolysis with ozone -- Treatment of discogenic low back pain with intradiscal electrothermal therapy (IDET): 24 months follow-up in 50 consecutive patients -- Percutaneous coblation nucleoplasty in patients with contained lumbar disc prolapse: 1 year follow-up in a prospective case series -- Plasma-mediated disc decompression for contained cervical disc herniation: results through 5 years -- Percutaneous laser discectomy: experience and long term follow-up -- Mechanism of action of oxygen ozone therapy in the treatment of disc herniation and low back pain -- Treatment of symptomatic lumbar spinal degenerative pathologies by means of combined conservative biochemical treatments -- Oxygen-ozone therapy for degenerative spine disease in the elderly: a prospective study -- Ozone: the one and only drug -- Vertebral augmentation: 7 years experience -- Kyphoplasty in the treatment of osteoporotic vertebral compression fractures (VCF) procedure description and analysis of the outcomes of 128 patients -- Experience with coflex interspinous implant -- DIAM device for low back pain in degenerative disc disease: 24 months follow-up -- Percutaneous surgical treatment in lumbar spinal stenosis with Aperius-PercLID: indications, surgical technique and results -- Six level cervico-thoracic circumferential reconstruction: report of the second case of the literature -- Percutaneous vertebral augmentation: StabilitiT: a new delivery system for vertebral fractures -- Minimally invasive disc preserving surgery in cervical radiculopathies: the posterior microscopic and endoscopic approach -- The fullendoscopic anterior cervical fusion: a new horizon for selective percutaneous endoscopic cervical decompression -- Leucocyte-platelet haemocomponents for topical use: regenerative potentiality -- Current surgical options for articular cartilage repair -- Facial-hypoglossal nerve end-to-side neurorrhaphy: anatomical study in rats -- Anatomic study in cadaver of the motor branch of the musculocutaneous nerve -- Exposure of the sciatic nerve in the gluteal region without sectioning the gluteus maximus: an anatomical and microsurgical study -- Experimental and clinical employment of end-to-side coaptation: our experience -- Considerations on the treatment of anterior interosseous nerve syndrome -- Percutaneous balloon compression of the gasserain ganglion for the treatment of trigeminal neuralgia: personal experience of 206 patients.
  • Digital/Print
    Roberto Scatena, Patrizia Bottoni, Bruno Giardina, editors.
    Digital : Springer2012
    Print2012
  • Digital
    editor, Jan Paul Ottervanger.
    Future Med2013
    The different faces of myocardial infarction / Jan Paul Ottervanger -- Epidemiology and classification of myocardial infarction / Michael Connolly & Ian Menown -- Risk factors for prognosis and secondary prevention of myocardial infarction / Daisaku Nakatani & Masatsugu Hori -- Pathophysiology of acute myocardial infarction / Panagiota Christia & Nikolaos G. Frangogiannis -- Symptoms and diagnosis of myocardial infarction/ Amber Marie Otten & Jan Paul Ottervanger -- Myocardial infarction imaging / Jagadeesh K. Kalavakunta, Imad Ahmado, Oliver G. Abela & George S. Abela -- Emergency management of ST-elevation myocardial infarction / Elliott Elias, Piera Capranzano & George Dangas -- Long-term care and prevention / Rebecca F. Rosenwasser, Katie Anderson & Benjamin J. Epstein -- Prognosis following myocardial infarction / Brandon K. Itagaki & Somjot S. Brar -- Future directions in the treatment of myocardial infarction / Jerome Roncalli -- Index.
  • Digital
    edited by Surendra Nimesh, Ramesh Chandra, Nidhi Gupta.
    ScienceDirect2017
    1. Nanomedicine for delivery of therapeutic molecules -- 2. Nanoparticles as nucleic acid delivery vectors -- 3. Methods for charactericzation of nanoparticles -- 4. Nanoparticles for DNA delivery -- 5. Nanoparticles for siRNA-mediated gene silencing -- 6. Nanoparticles for locked nucleic acid delivery -- 7. Nanoparticles for ribozymes delivery -- 8. Nanoparticles for DNAzymes delivery -- 9. Pharmacokinetics and biodistribution of the nanoparticles -- 10. Nanotoxicology: evaluation of toxicity potential of nanoparticles -- 11. Regulatory aspects of nanoparticulate mediated nucleic acid delivery systems -- 12. Clinical studies and future prospects -- Index.
  • Digital
    editor, Kjell Öberg.
    Future Med2011
    Advances in neuroendocrine tumor management / Kjell Öberg -- Classification of digestive neuroendocrine neoplasm / Guido Rindi & Frediano Inzani -- Molecular profile and diagnosis / Christos Toumpanakis -- Surgical approach / Rossella Bettini & Massimo Falconi -- Somatostatin analogs / Wouter W. de Herder -- Combinational chemotherapy and radiotherapy / Emilio Bajetta, Emilio Bombardieri, Laura Catena, Monica Valente & Nadia Bianco -- Which therapy for which patient? / Kjell Öberg.
  • Digital
    Robert Kozma, Robinson E. Pino, Giovanni E. Pazienza, editors.
    Springer2012
    Physical implementation of the memristor at industrial scale sparked the interest from various disciplines, ranging from physics, nanotechnology, electrical engineering, neuroscience, to intelligent robotics. As any promising new technology, it has raised hopes and questions; it is an extremely challenging task to live up to the high expectations and to devise revolutionary and feasible future applications for memristive devices. The possibility of gathering prominent scientists in the heart of the Silicon Valley given by the 2011 International Joint Conference on Neural Networks held in San Jose, CA, has offered us the unique opportunity of organizing a series of special events on the present status and future perspectives in neuromorphic memristor science. This book presents a selection of the remarkable contributions given by the leaders of the field and it may serve as inspiration and future reference to all researchers that want to explore the extraordinary possibilities given by this revolutionary concept.
  • Digital
    Niall M. Adams, Paul S. Freemont, editors.
    Springer2011
  • Digital/Print
    Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione, editors.
    Digital : Springer2014
    Print2014
    This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed nutrition and cancer from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the -omics) that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions. Advances in Nutrition and Cancer will be an invaluable source of topical information for all researchers and clinicians with an interest in this field.
  • Digital
    editor, Peter E. Schwartz.
    Future Med2012
    Advances in ovarian cancer management / Peter E. Schwartz -- Etiology and overview / Gang Ye, Stefanie Bernaudo & Chun Peng -- Diagnostic imaging in the management of ovarian masses / Amit Mahajan, Indukala Doddamane & Shirley McCarthy -- Initial surgical management of ovarian cancer / Jason Knight & Peter G. Rose -- Initial chemotherapy for the treatment of ovarian cancer / Katherine M. Moxley & Robert S. Mannel -- Neoadjuvant chemotherapy in the management of advanced ovarian cancer / Peter E. Schwartz -- Intraperitoneal chemotherapy : its use in epithelial ovarian cancer / Neesha Dhani & Helen Mackay -- Chemotherapeutic management of recurrent ovarian cancer / Marcia Hall -- Emerging chemotherapy agents in ovarian cancer / Daliah Tsoref & Amit M. Oza -- Surgical management of recurrent ovarian cancer / Eelco de Bree -- Angiogenesis in ovarian cancer / Vincent Castonguay & Amit M. Oza -- Antigen-specific immunotherapy for ovarian cancer / Dana M. Roque & Alessandro D. Santin -- Poly(ADP-ribose) polymerase inhibitors and epithelial ovarian cancer -- Thomas P. McNally, Gillianne G.Y. Lai & Richard T. Penson -- Emerging targeted therapies / Mirko Marabese & Massimo Broggini -- Palliative care in ovarian cancer / Cynthia O'Sullivan, Elizabeth Ercolano & Ruth McCorkle -- Guidelines in ovarian cancer / Domenica Lorusso, Antonella Pietragalla & Giovanni Scambia -- Index.
  • Digital
    editors Bai-Chuang Shyu and Makoto Tominaga.
    Springer2018
    This book summarizes the latest advances in pain research. All the chapters were contributed by speakers from Asian Pain Symposium (APS) on Acute and Chronic Pain, which was held in Taipei in 2017. Founded in Kyoto, Japan in 2000, the APS serves as a platform for scientists to present recent findings in pain research and discuss research orientation in this field. APS 2017 focused on novel strategies for pain treatment. Written by experts from various disciplines, from molecular to functional, and from basic to clinic studies, this book is composed of 18 review articles on the physiology and pathology of pain in these research fields. Specific topics include circuitry, neurotransmitter, physiology, behavior, neuropathology, pharmacology, and the treatments for neuropathic pain disorders. The book is a valuable resource for researchers and graduate students in pain medicine and neuroscience.
  • Digital
    editors, Helmut Friess, Norbert Hüser.
    Future Med2011
    Advances in pancreatic cancer treatment / Helmut Friess & Norbert Hüser -- Pathophysiology of pancreatic cancer / J. Matthias Löhr, Stephan L. Haas & Rainer Heuchel -- Molecular diagnostics in pancreatic cancer / David K. Chang, Sean M. Grimmond & Andrew V. Biankin -- Surgical therapy for pancreatic cancer / Norbert Hüser, Volker Assfalg & Helmut Friess -- Multimodal treatment concepts in pancreatic cancer / Daniel Reim, Alexander Novotny & Helmut Friess -- Consensus guidelines in pancreatic cancer treatment / Wasif Saif -- Drugs in clinical trials & future directions / Zhiqiang Huang & Donald J. Buchsbaum.
  • Digital
    editor, Joseph H. Friedman.
    Future Med2011
    Advances in Parkinson's disease management / Joseph H. Friedman -- Etiology and overview / Witold Polanski -- Biomarkers of Parkinson's disease / Mauro Fasano & Tiziana Alberio -- Imaging Parkinson's disease / David J. Brooks -- Dopaminergic agents / Lawrence W. Elmer & Robert A. Hauser -- Combined dopaminergic and nondopaminergic therapies / Mary Ann Thenganatt & Cheryl H. Waters -- Future drug therapy / Makoto Naoi & Wakako Maruyama -- Drug therapies for neuropsychiatric and autonomic disturbances in patients with PD / Thomas Müller -- Surgical treatment for Parkinson's disease / Sumito Sato & Hideki Mochizuki -- Cell and gene transplantation for Parkinson's disease : from the clinic / Paul E. Greene -- Current evidence-based guidelines for the management of Parkinson's disease / Nicolas Phielipp & Janis Miyasaki -- Index.
  • Print
    edited by Rowena Korobkin, Christian Guilleminault.
    Status: Not Checked Out
  • Digital
    Salvador Nares, editor.
    Springer2020
    This book describes practical, contemporary, and evidence-based surgical approaches for the treatment of diseases and conditions affecting the periodontium, including advanced forms of periodontal disease, gingival recession, and complex cases requiring interdisciplinary management. The book opens by identifying key considerations in periodontal surgery, for example with regard to diagnosis and prognosis, and by presenting decision trees that will be useful in daily practice. Cutting-edge resection and regeneration techniques for the treatment of periodontitis and mucogingival surgical procedures for the management of soft tissue deficiencies are then described and illustrated in detail, highlighting important tips and tricks as well as potential difficulties and complications. The final part of the book is devoted to interdisciplinary care, which is of key importance when periodontal surgery is indicated in the management of cases requiring orthodontic, endodontic, and restorative therapy. Advances in Periodontal Surgery will be of value for practitioners at all levels of experience as well as for students entering the field.
  • Digital
    editor, Dimitrios H. Roukos.
    Future Med2011
    Personalized genomic medicine: is a cancer care revolution achievable? / Dimitrios H. Roukos -- Targeting the individual cancer patient / Georgios Baltogiannis, Christos S. Katsios & Dimitrios H. Roukos -- Biomarkers-guided targeted drugs: new clinical trials design and practice necessity / Ming-Wen An, Sumithra J. Mandrekar & Daniel J. Sargent -- Personalized management for breast cancer / George C. Zografos, Dimosthenis T. Chrysikos, Paraskevi Liakou & Flora Zagouri -- Personalized management for non-small-cell lung cancer / Martin Früh, Florent Baty, Lukas Kern, Martin P. Putora & Martin Brutsche -- Personalized management for colorectal cancer / Ana Custodio & Jaime Feliu -- Successes, challenges and future directions / Stephen J. Clarke.
  • Digital
    editor, Nagahiro Saijo.
    Future Med2011
    Advances in personalized therapy for lung cancer / Nagahiro Saijo -- Biomarkers in lung cancer / Tobenna Nwizu & Ravi Salgia -- EGF receptor-targeted drugs / Tetsuya Mitsudomi -- Antiangiogenic therapies for non-small-cell lung cancer / Suresh S. Ramalingam & Chandra P. Belani -- DNA-targeted drugs / Judith Meza-Junco & Michael B. Sawyer.
  • Digital
    Golubnitschaja, Olga.
    Springerv. 1-, 2012-
  • Digital
    edited by Jeffrey M. Weinberg, Mark Lebwohl.
    Springer2014
    The understanding and management of psoriasis have evolved dramatically over the last decades and, as a result, guidelines and treatment options have changed dramatically. To meet the need for a up-to-date practical resource in this area, the Editors have brought together a team of experts in the field to produce a highly informative and illustrated guide to the decision-making process for psoriasis. Advances in Psoriasis: A Multisystemic Guide provides physicians with a reference on the disease and its comorbidities and therapeutic options. It will help physicians further their knowledge of the science and therapy of psoriasis. As well as practicing dermatologists, fellows in dermatology will find this book to be an essential training resource to learn about the treatment and management of psoriasis.
  • Digital/Print
    Wise, Thomas N.
    Digital : Kargerv. 5-, 1967-
  • Digital
    Mieczyslaw Pokorski, editor.
    Springer2019
  • Digital
    editor, Kjell Öberg.
    Future Med2013
    Advances in pulmonary neuroendocrine tumor management / Kjell Öberg -- Classification / Mauro Papotti -- Molecular imaging & peptide receptor radionuclide therapy / Richard P. Baum, Harshad R. Kulkarni & Dieter Hörsch -- Biotherapy : somatostatin analogs and IFN-[alpha] / Dan Granberg -- Typical and atypical bronchial carcinoid tumors / Michael Beckles, Dalvinder Mandair, Christos Toumpanakis & Martyn Caplin -- Small-cell lung cancer and large-cell neuroendocrine tumors of the lung / David Planchard & Eric Baudin -- Thymic neuroendocrine tumors / Piero Ferolla -- Algorithm for management of bronchopulmonary neuroendocrine tumors / Kjell Öberg -- Index.
  • Digital/Print
    Jeffrey Y.C. Wong, Timothy E. Schultheiss, Eric H. Radany, editors.
    Digital : Springer2017
    Print2017
    Combining radiotherapy and immunotherapy -- SBRT and the treatment of oligometastatic disease -- MRI guided radiotherapy -- Oncologic applications of magnetic resonance guided focused ultrasound -- Intensity-modulated proton beam therapy of prostate cancer- history, results, and future directions -- IGRT and hypofractionation for primary tumors -- The impact of IGRT on normal tissue toxicity -- Biologic and image guided systemic radiotherapy -- Cancer stem cells and tumor microenvironment in radiotherapy -- Biomarkers and radiotherapy -- The mammalian DNA damage response as a target for therapeutic gain in radiation oncology -- Mathematical modeling in radiation oncology.
  • Digital
    Branislav Jeremić (editor) ; foreword by Luther W. Brady ... [et al.].
    Springer2011
  • Digital
    volume editors, M. Guckenberger, S.E. Combs, D. Zips.
    Karger2018
    Principles and developments in cancer immunotherapy and approaches for combination with tumour irradiation / Eckert, F., Huber, S. -- Imageable biomarkers for radiotherapy response / van der Weg, WW., Span, P.N., Braam, P.M., Bussink, J. -- Targeting tumor microenvironment and metabolism to overcome radiation resistance / Sharma, A., Pruschy, M. -- Imaging for target volume definition and response assessment in lung cancer / De Ruysscher, D., van Elmpt, W. -- Advances in technology and its application : radiotherapy treatment planning / Alber, M. -- Stereotactic body radiotherapy / Guckenberger, M. -- Clinical rationale and indications for particle therapy / Dreher, C, Combs, S.E. -- Advances in radiation biology of particle irradiation / Helm, A., Tinganelli, W., Durante, M. -- Preclinical mouse models for the evaluation of novel techniques in particle therapy / Schmid, T.E., Multhoff, G.
  • Digital
    Gabriella Castoria, Antimo Migliaccio, editors.
    Springer2012
    [1.] Non-genomic Action of Steroid Hormones: More Questions than Answers / Antimo Migliaccio, Gabriella Castoria, Antonio Bilancio, Pia Giovannelli, Marzia Di Donato and Ferdinando Auricchio -- Part I. Breast Cancer -- [2.] Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling / Guillermo P. Vicent, Roser Zaurin, Cecilia Ballaré, A. Silvina Nacht, Roni H. G. Wright, Francois Le Dily, Giancarlo Castellano, Jofre Font-Mateu and Miguel Beato -- [3.] Cooperative Interactions Between c-Src, Estrogen Receptors and Receptor Tyrosine Kinases in Breast Cancer / Sarah J. Parsons, Jessica E. Pritchard, Emily M. Fox and Margaret A. Shupnik -- [4.] Cross Talk Between ER[alpha] and Src Signaling and Its Relevance to ER Status and Hormone Responsiveness / Jun Sun, Wen Zhou, Zafar Nawaz and Joyce M. Slingerland -- [5.] Post-translational Modifications of ER Alpha in Rapid Estrogen's Action / Muriel Le Romancer, Coralie Poulard, Stéphanie Sentis, and Laura Corbo -- [6.] Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancer / Marina Ines Flamini, Angel Matias Sanchez, Xiao-Dong Fu and Tommaso Simoncini -- [7.] Unraveling the Role of GPER in Breast Cancer / Rosamaria Lappano and Marcello Maggiolini -- [8.] Nongenomic Actions of Estrogens and Xenoestrogens Affecting Endocrine Cancer Cells / Cheryl S. Watson, Dragoslava Zivadinovic, Yow-Jiun Jeng, Rebecca A. Alyea, Terumi Midoro-Horiuti, Randall Goldblum and Anannya Banga -- Part II. Prostate Cancer -- [9.] Differential Functions of Stromal and Epithelial Androgen Receptor in Prostate Cancer Before and After Castration Resistant Stage / S. Lee, K.-P. Lai, S. Yeh and C. Chang -- [10.] Role of Androgens and Androgen Receptor in Prostate Cancer: Genomic and Non-Genomic Actions / Sara Marchiani, Lara Tamburrino, Monica Muratori, Lorella Bonaccorsi, Gianni Forti and Elisabetta Baldi -- [11.] Mechanisms of Signal Transduction in Prostate Cancer: The Role of PI3-Kinase Pathway in Androgen Action / Laurent Morel and Silvère Baron -- [12.] The IGF-I Axis in Prostate Cancer: The Role of Rapid Steroid Actions / Antonino Belfiore -- Androgen Receptor Pathway in Prostate Cancer: Old Target and New Drugs / Christophe Massard and Karim Fizazi -- Part III. New Tools for Steroid Receptor Analysis and Regulatory Networks -- [13.] Quantitative Visualization of Sex Steroid Receptor Functions: AR and ER[alpha] / Michael J. Bolt, Sean M. Hartig, Adam T. Szafran, Sanjay N. Mediwala, Marco Marcelli and Michael A. Mancini -- [14.] Micropatterned Surfaces as Tools for the Study of the Rapid Non-genomic Actions of Steroid Receptors / Andrew C. B. Cato, Emmanuel Oppong and Sylwia Sekula-Neuner.
  • Digital
    edited by Venkatram Prasad Shastri, George Altankov, Andreas Lendlein.
    Springer2010
    Cell Adhesions and Signaling: A Tool for Biocompatibility Assessment / Roumen Pankov and Albena Momchilova -- Development of Provisional Extracellular Matrix on Biomaterials Interface: Lessons from In Vitro Cell Culture / George Altankov, Thomas Groth, Elisabeth Engel, Jonas Gustavsson and Marta Pegueroles, et al. -- Endothelial Progenitor Cells for Tissue Engineering and Tissue Regeneration Endothelial Progenitor Cells / Joyce Bischoff -- Dermal Precursors and the Origins of the Wound Fibroblast / Jeffrey M. Davidson -- Cell Based Therapies: What Do We Learn from Periosteal Osteochondrogenesis? / Peter J. Emans, Tim J. M. Welting and Venkatram Prasad Shastri -- Bioreactor Systems in Regenerative Medicine / Ivan Martin, Stefania A. Riboldi and David Wendt -- Biomimetic Approaches to Design of Tissue Engineering Bioreactors / Bojana Obradovic, Milica Radisic and Gordana Vunjak-Novakovic -- The Nature of the Thermal Transition Influences the Shape-Memory Behavior of Polymer Networks / Andreas Lendlein, Marc Behl and Stefan Kamlage -- Nanoengineered Systems for Regenerative Medicine Surface Engineered Polymeric Biomaterials with Improved Bio-Contact Properties / Todorka Vladkova and Natalia Krasteva -- Nanocomposites for Regenerative Medicine / Ryan Hoshi, Antonio R. Webb, Hongjin Qiu and Guillermo A. Ameer -- Role of Spatial Distribution of Matricellular Cues in Controlling Cell Functions / Daniela Guarnieri and Paolo A. Netti -- Materials Surface Effects on Biological Interactions / Josep A. Planell, Melba Navarro, George Altankov, Conrado Aparicio and Elisabeth Engel, et al. -- Chemical and Physical Modifications of Biomaterial Surfaces to Control Adhesion of Cells / Thomas Groth, Zhen-Mei Liu, Marcus Niepel, Dieter Peschel and Kristin Kirchhof, et al. -- Results of Biocompatibility Testing of Novel, Multifunctional Polymeric Implant Materials In-Vitro and In-Vivo / Dorothee Rickert, Rosemarie Fuhrmann, Bernhard Hiebl, Andreas Lendlein and Ralf-Peter Franke -- UFOs, Worms, and Surfboards: What Shapes Teach Us About Cell-Material Interactions / Julie A. Champion and Samir Mitragotri -- Nano-engineered Thin Films for Cell and Tissue-Contacting Applications / Richard F. Haglund -- Injectable Hydrogels: From Basics to Nanotechnological Features and Potential Advances / Biancamaria Baroli -- Polyelectrolyte Complexes as Smart Nanoengineered Systems for Biotechnology and Gene Delivery / Vladimir A. Izumrudov.
  • Digital/Print
    Mieczyslaw Pokorski, editor.
    Digital : Springer2016
    Print2016
    The role of dysregulated microRNA expression in lung cancer / M. Krutakova [and seven others] -- Laryngeal cancer: 12-year experience of a single center / V. Calkovsky, P. Wallenfels, A. Calkovska, A. Hajtman -- Polymorphisms of selected DNA repair genes and lung cancer in chromium exposure / E. Halasova, [and nine others] -- Associations of CYP1A2 polymorphisms with the risk haplotypes in lung cancer in the Slovak population -- T. Matakova, E. Halasova, A. Dzian, R. Hruby, M. Halasa, K. Javorka, M. Skerenova -- Impact of endobronchial ultrasound guided transbronchial needle aspiration on diagnostic yield of bronchoscopy in patients with mediastinal lymph node enlargement -- K. Osinka, M. Zielińska-Krawczyk, P. Korczyński, B. Górnicka, R. Krenke -- The effect on cognition of mitochondrial respiratory system proteins in peripheral blood mononuclear cells in the course of lung cancer -- S. Michalak, J. Rybacka-Mossakowska, J. Gazdulska, I. Gołda-Gocka, R. Ramlau -- Lung cancer and multiple neoplasms: a retrospective analysis -- A. Romaszko, E. Świetlik, A. Doboszyńska, P. Szpruch, J. Luks -- Humoral immune response against neural antigens and its effects on cognition in lung cancer patients -- J. Rybacka-Mossakowska, R. Ramlau, J. Gazdulska, I. Gołda-Gocka, W. Kozubski and S. Michalak. -- Active case finding among homeless people as a means of reducing the incidence of pulmonary tuberculosis in general population -- J. Romaszko, A. Siemaszko, M. Bodzioch, A. Buciński, A. Doboszyńska -- Cryptogenic organizing pneumonia: IL-1[beta], IL-6, IL-8, and TGF- [beta]1 serum concentrations and response to clarithromycin treatment -- E. Radzikowska and [six others].
  • Digital
    Charles F. Streckfus.
    Springer2015
    This book reviews the progress made in salivary diagnostics and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of ℓ́ℓsalivaomicsℓ́ℓ is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
  • Digital
    Wagner F. Gattaz, Geraldo Busatto, editors.
    Springer2010
  • Digital
    Kazuya Tamai, Eiji Itoi, Kenji Takagishi, editors.
    Springer2016
    Chapter 1. Anatomy -- Chapter 2. Biomechanics -- Chapter 3. Kinematics and Motion Analysis -- Chapter 4. Advanced MR Imaging of the Shoulder -- Chapter 5. Transosseous-Equivalent Arthroscopic Bankart Repair by Twin Anchor Footprint Fixation (TAFF) Technique using JuggerKnot Soft Anchor -- Chapter 6. Complications of Arthroscopic Surgery -- Chapter 7 Instability -- Chapter 8. Arthroscopic Rotator Cuff Repair -- Chapter 9. Mini-Open Rotator Cuff Repair -- Chapter 10. Massive and Irreparable Rotator Cuff Tears -- Chapter 11. Superior Capsule Reconstruction for Massive Rotator Cuff Tears -- Chapter 12. Tendon Transfer for Massive Rotator Cuff Tear -- Chapter 13. Frozen Shoulder -- Chapter 14. Nerve Lesions Around the Shoulder -- Chapter 15. Proximal Humeral Fractures - Classification and Treatment -- Chapter 16. Reverse Shoulder Arthroplasty -- Chapter 17. Physical Therapy- Tips and Pitfalls.
  • Digital
    volume editor, Karl Lenhard Rudolph.
    Karger2012
    Speakers at the symposium / Morita, M. -- Aging of the niche and the microenvironment and its role in stem cell aging / Geiger, H. -- Hematopoietic stem cell aging and cancer / Chen, Y., Ju, Z. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Kleinhans, K.N., Burkhalter, M.D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Morita, Y. -- Stem cell therapy and stress response in pancreas and intestine -- Sperka, T., Omrani, O. -- Niche-stem cell interations and environmental influences / Tang, D. -- Stem cells and metabolism / Missios, P., Guachalla, L. -- Molecular mechanisms of muscle stem cell aging / Baig, A.H., Tümpel, S. -- Neural stem cells in development and aging / Schmidt-Strassburger, U.
  • Digital
    Hossein Baharvand, Nasser Aghdami, editors.
    Springer2012
    Advances in stem cell research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
  • Digital/Print
    Igor I. Goryanin, Andrew B. Goryachev, editors.
    Digital : Springer2012
    Print2012
    Part 1. Multiscale biological networks: identification, modeling and analysis -- Modular Analysis of Biological Networks / Hans-Michael Kaltenbach and Jörg Stelling -- Modeling Signaling Networks Using High-throughput Phospho-proteomics / Camille Terfve and Julio Saez-Rodriguez -- An Integrated Bayesian Framework for Identifying Phosphorylation Networks in Stimulated Cells / Tapesh Santra, Boris Kholodenko and Walter Kolch -- Signaling Cascades: Consequences of Varying Substrate and Phosphatase Levels / Elisenda Feliu, Michael Knudsen and Carsten Wiuf -- Heterogeneous Biological Network Visualization System: Case Study in Context of Medical Image Data / Erno Lindfors, Jussi Mattila, Peddinti V. Gopalacharyulu, Antti Pesonen and Jyrki Lötjönen, et al. -- Evolution of the Cognitive Proteome: From Static to Dynamic Network Models / J. Douglas Armstrong and Oksana Sorokina -- Molecular Systems Biology of Sic1 in Yeast Cell Cycle Regulation Through Multiscale Modeling / Matteo Barberis -- Proteome-Wide Screens in Saccharomyces cerevisiae Using the Yeast GFP Collection / Yolanda T. Chong, Michael J. Cox and Brenda Andrews -- Unraveling the Complex Regulatory Relationships Between Metabolism and Signal Transduction in Cancer / Michelle L. Wynn, Sofia D. Merajver and Santiago Schnell -- Part 2. Cellular decision making: adaptation, differentiation and death -- The Cell as a Thermostat: How Much does it Know? / Dennis Bray -- Stem Cell Differentiation as a Renewal-Reward Process: Predictions and Validation in the Colonic Crypt / Kiran Gireesan Vanaja, Andrew P. Feinberg and Andre Levchenko -- A Dynamic Physical Model of Cell Migration, Differentiation and Apoptosis in Caenorhabditis elegans / Antje Beyer, Ralf Eberhard, Nir Piterman, Michael O. Hengartner and Alex Hajnal, et al. -- A Modular Model of the Apoptosis Machinery / E. O. Kutumova, I. N. Kiselev, R. N. Sharipov, I. N. Lavrik and Fedor A. Kolpakov -- An Ensemble Approach for Inferring Semi-quantitative Regulatory Dynamics for the Differentiation of Mouse Embryonic Stem Cells Using Prior Knowledge / Dominik Lutter, Philipp Bruns and Fabian J. Theis -- Cell Death and Life in Cancer: Mathematical Modeling of Cell Fate Decisions / Andrei Zinovyev, Simon Fourquet, Laurent Tournier, Laurence Calzone and Emmanuel Barillot -- Theoretical Aspects of Cellular Decision-Making and Information-Processing / Tetsuya J. Kobayashi and Atsushi Kamimura -- Zooming in on Yeast Osmoadaptation / Clemens Kühn and Edda Klipp -- Part 3. Spatial and temporal dymensions of intracellular dynamics -- Receptor Dynamics in Signaling / Verena Becker, Jens Timmer and Ursula Klingmüller -- A Systems-Biology Approach to Yeast Actin Cables / Tyler Drake, Eddy Yusuf and Dimitrios Vavylonis -- Modeling Morphodynamic Phenotypes and Dynamic Regimes of Cell Motion / Mihaela Enculescu and Martin Falcke -- Time-Structure of the Yeast Metabolism In vivo / Kalesh Sasidharan, Masaru Tomita, Miguel Aon, David Lloyd and Douglas B. Murray -- Coarse Graining Escherichia coli Chemotaxis: From Multi-flagella Propulsion to Logarithmic Sensing / Tine Curk, Franziska Matthäus, Yifat Brill-Karniely and Jure Dobnikar -- Self-Feedback in Actin Polymerization / Anders E. Carlsson -- Part 4. Computational tools, algorithms and theoretical methods for systems biology -- Global Optimization in Systems Biology: Stochastic Methods and Their Applications / Eva Balsa-Canto, J. R. Banga, J. A. Egea, A. Fernandez-Villaverde and G. M. de Hijas-Liste -- Mathematical Modeling of the Human Energy Metabolism Based on the Selfish Brain Theory / Matthias Chung and Britta Göbel -- Identification of Sensitive Enzymes in the Photosynthetic Carbon Metabolism / Renato Umeton, Giovanni Stracquadanio, Alessio Papini, Jole Costanza and Pietro Liò, et al. -- Formal Methods for Checking the Consistency of Biological Models / Allan Clark, Vashti Galpin, Stephen Gilmore, Maria Luisa Guerriero and Jane Hillston -- Global Parameter Identification of Stochastic Reaction Networks from Single Trajectories / Christian L. Müller, Rajesh Ramaswamy and Ivo F. Sbalzarini -- A Systems Biology View of Adaptation in Sensory Mechanisms / Pablo A. Iglesias -- Leveraging Modeling Approaches: Reaction Networks and Rules / Michael L. Blinov and Ion I. Moraru -- Part 5. Applications of systems biology in medicine, biotechnology and pharmaceutical industry -- Why and How to Expand the Role of Systems Biology in Pharmaceutical Research and Development / Robert D. Phair -- Multiscale Mechanistic Modeling in Pharmaceutical Research and Development / Lars Kuepfer, Jörg Lippert and Thomas Eissing -- Re-analysis of Bipolar Disorder and Schizophrenia Gene Expression Complements the Kraepelinian Dichotomy / Kui Qian, Antonio Di Lieto, Jukka Corander, Petri Auvinen and Dario Greco -- Bringing Together Models from Bottom-Up and Top-Down Approaches: An Application for Growth of Escherichia coli on Different Carbohydrates / Andeas Kremling -- A Differential Equation Model to Investigate the Dynamics of the Bovine Estrous Cycle / H. M. T. Boer, C. Stötzel, S. Röblitz and H. Woelders -- Reducing Systems Biology to Practice in Pharmaceutical Company Research; Selected Case Studies / N. Benson, L. Cucurull-Sanchez, O. Demin, S. Smirnov and P. van der Graaf -- System-Scale Network Modeling of Cancer Using EPoC / Tobias Abenius, Rebecka Jörnsten, Teresia Kling, Linnéa Schmidt and José Sánchez, et al. -- Early Patient Stratification and Predictive Biomarkers in Drug Discovery and Development / Daphna Laifenfeld, David A. Drubin, Natalie L. Catlett, Jennifer S. Park and Aaron A. Van Hooser, et al. -- Biomedical Atlases: Systematics, Informatics and Analysis / Richard A. Baldock and Albert Burger.
  • Digital
    Dale A. Schoeller & Margriet Westerterp-Plantenga.
    TandFonline2017
    "Considerable evidence proves that self-reported dietary intake using written diaries or recalls are subject to bias resulting in poor accuracy. While dietary intake data are needed to drive many nutritional policies, the obesity epidemic has increased the need to assess diet with absolute accuracy. This book reviews the field of research methods in dietary assessment. Chapters cover laboratory and free-living dietary methods; computer-assisted recall methods; dietary energy intake models; dietary and isotopic biomarkers; photographic diet diaries; chewing and swallowing sensors for detection; and novel electronic monitoring devices under investigation."--Provided by publisher.
  • Digital
    edited by Peter Muir.
    Wiley2018
    Front Matter -- Structure and Function -- Structure and Function. Morphology and Function of the Cruciate Ligaments / Hilde de Rooster, Eithne Comerford -- Biomechanics of the Cruciate Ligaments / Susannah J Sample -- Cruciate Ligament Remodeling and Repair / Connie S Chamberlain, Erin E Crowley, Ray Vanderby -- Meniscal Structure and Function / Antonio Pozzi, James L Cook -- Biomechanics of the Normal and Cranial Cruciate Ligament-Deficient Stifle / Antonio Pozzi, Stanley E Kim -- Etiopathogenesis of Cruciate Ligament Rupture -- Etiopathogenesis of Cruciate Ligament Rupture. Histology of Cruciate Ligament Rupture / Kei Hayashi -- Genetics of Cruciate Ligament Rupture / Lauren A Baker, Peter Muir -- Cruciate Ligament Matrix Metabolism and Development of Laxity / Eithne Comerford -- Morphological Risk Factors for Cruciate Ligament Rupture / Eithne Comerford -- Role of Nitric Oxide Production and Matrix Protease Activity in Cruciate Ligament Degeneration / David E Spreng, Simone Forterre -- Role of Antibodies to Collagen Type I and II / Hilde de Rooster, Eithne Comerford -- Synovitis Precedes Stifle Instability Associated with Cruciate Ligament Rupture / Jason A Bleedorn -- Role of Synovial Immune Responses in Stifle Synovitis / Peter Muir -- Clinical Features -- Clinical Features. Epidemiology of Cruciate Ligament Rupture / Lauren A Baker, Peter Muir -- History and Clinical Signs of Cruciate Ligament Rupture / Peter Muir -- Partial Rupture of the Cranial Cruciate Ligament / Peter Muir -- Caudal Cruciate Ligament Rupture / Peter Muir -- Stress Imaging of the Stifle / Stanley E Kim -- Stifle Ultrasonography / Cristi R Cook -- Computed Tomography (CT) of the Stifle / Ingrid Gielen, Henri van Bree -- Magnetic Resonance Imaging of the Stifle / Peter V Scrivani -- Risk Prediction of Cruciate Ligament Rupture using Stifle Diagnostic Imaging / Peter Muir -- Surgical Treatment -- Surgical Treatment. Arthroscopy and Arthrotomy of the Stifle / Brian S Beale, Donald A Hulse, Antonio Pozzi, Peter Muir -- Joint Lavage / Peter Muir -- Extracapsular Stabilization / Selena Tinga, Stanley E Kim -- Intra-Articular Repair for Cranial Cruciate Ligament Rupture in the Dog / Jeffery J Biskup, Michael G Conzemius -- Tibial Plateau Leveling Osteotomy / Susan L Schaefer -- Tibial Tuberosity Advancement / Randy J Boudrieau -- Closing Cranial Wedge Ostectomy and Triple Tibial Osteotomy / Simon C Roe -- Treatment of Excessive Tibial Plateau Angle / Michael P Kowaleski -- Surgical Management of Cruciate Ligament Rupture Combined with Patella Luxation / Anke Langenbach, Denis J Marcellin-Little -- Biomechanics of the Cranial Cruciate Ligament-Deficient Stifle Treated by Tibial Osteotomies / Antonio Pozzi, Stanley E Kim, Selena Tinga -- Arthroscopic Follow-Up after Surgical Stabilization of the Stifle / Brian S Beale, Donald A Hulse -- Cranial Cruciate Ligament Debridement / David E Spreng -- Surgical Treatment of Concurrent Meniscal Injury / Samuel P Franklin, James L Cook, Antonio Pozzi -- Meniscal Release / Antonio Pozzi, James L Cook -- Progression of Osteoarthritis after Stifle Stabilization Surgery / Susannah J Sample -- Clinical Outcomes after Surgical Treatment of Cruciate Ligament Rupture / Mary Sarah Bergh, Steven C Budsberg -- Success and Failure after Stifle Stabilization Surgery / Michael G Conzemius, Richard B Evans -- Diagnosis and Management of Orthopaedic Infection after Stifle Surgery / Noël MM Moens -- Medical Management of Cruciate Ligament Rupture -- Medical Management of Cruciate Ligament Rupture. Medical Therapy for Stifle Osteoarthritis / Steven C Budsberg -- Rehabilitation for Dogs with Cruciate Ligament Rupture / Denis J Marcellin-Little, Courtney J Arnoldy -- Future Directions -- Future Directions. Clinical Research Design and Patient-Oriented Outcomes / Dorothy Cimino Brown -- Total Knee Replacement in the Dog / Matthew J Allen, William D Liska, Valentina Brioschi -- Regenerative Medicine and Cranial Cruciate Ligament Repair / Gabriel S Perrone, Martha M Murray, Patrick Vavken -- Disease-Modifying Medical and Cell-Based Therapy / Susannah J Sample, Peter Muir.
  • Digital
    editors, Kimberly A. Smith, Dustin R. Fraidenburg, Jason X.-J. Yuan
    Future Med2013
    Current therapies for the treatment of pulmonary arterial hypertension / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Etiology and prevalence of pulmonary arterial hypertension / Catharina Belge & Marion Delcroix -- Pathology and diagnosis of pulmonary arterial hypertension / Carlyne D. Cool -- Conventional therapy / Stefania Cicalini & Nicola Petrosillo -- Targeted therapies : prostaglandins / Benton Ashlock & David Poch -- Targeted therapies : endothelin receptor antagonists / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Stimulators and activators of soluble guanylate cyclase : potential therapeutic indications / Bobby D. Nossaman, George F. Lasker, Edward A. Pankey, Raj D. Parikh & Philip J. Kadowitz -- Surgical approaches in pulmonary arterial hypertension / Vaidehi Kaza, Jodie Moore, Srinivas Bollineni & Fernando Torres -- Monitoring and prognosis of pulmonary arterial hypertension / Melanie J. Brewis & Andrew J. Peacock -- Right ventricular failure / Raj Parikh & Philip J. Kadowitz -- Index.
  • Digital
    volume editor, T. Hugh Jones.
    Karger2009.
    Current guidelines for the diagnosis of testosterone deficiency / S. Arver, M. Lehtihet -- Laboratory measurement of testosterone / M.J. Diver -- Advances in testosterone replacement therapy / L.J.G. Gooren -- The role of the CAG repeat androgen receptor polymorphism in andrology / M. Zitzmann -- Late-onset hypogonadism / L.J.G Gooren -- Testosterone in obesity, metabolic syndrome, and type 2 diabetes / R.D. Stanworth, T.H. Jones -- Testosterone and coronary artery disease / J.E. Nettleship ... [et al.] -- Erectile dysfunction and testosterone deficiency / M. Blute ... [et al.] -- Testosterone, bone, and osteoporosis / S.P. Tuck, R.M. Francis -- Frailty and muscle function : role for testosterone? / U. Srinivas-Shankar, F.C.W. Wu -- Testosterone effects on cognition in health and disease / M.M. Cherrier -- Anabolic applications of androgens for functional limitations associated with aging and chronic illness / S. Bhasin, T.W. Storer -- Testosterone in chronic heart failure / C.J. Malkin, T.H. Jones, K.S. Channer -- Testosterone and prostate safety / A. Morgentaler, C. Schulman.
  • Digital
    editors, Clifford A. Hudis, Tiffany A. Traina.
    Future Med2011
    Advances in the management of triple-negative breast cancer / Tiffany A. Traina & Clifford A. Hudis -- Etiology and risk factors / Laura Fejerman & Elad Ziv -- Diagnosis and pathology / Govardhanan Nagaiah & Jame Abraham -- Molecular subtypes and emerging therapeutic opportunities / Anastasia Constantinidou, Robin L. Jones & Jorge S. Reis-Filho -- Molecular profile of triple-negative breast cancer / Leonel F. Hernandez-Aya & Ana Maria Gonzalez-Angulo -- Role of metabolic rehabilitation-based approach in TNBC : biguanide metformin and more / Lev M. Berstein, Garik A. Dashyan & Vladimir F. Semiglazov -- Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer / Mark Robson -- Targeted therapies: EGFR inhibitors / Farrah M. Datko & Maura N. Dickler -- Targeted therapies : other agents in clinical trials / Brian R. Haney, Nathan M. Shumway & George E. Peoples -- Combined therapies and future directions / Anastasia Pazaiti & Ian S. Fentiman.
  • Digital
    editor, Michael D. Prados.
    Future Med2012
    Advances in the pathogenesis and treatment of glioblastoma multiforme / Michael Prados -- Pathogenesis, molecular characteristics and prognostic factors for survival / Keith L. Ligon -- Standard treatment approaches for newly diagnosed glioblastoma / Soon-Tae Lee & Patrick Y. Wen -- Targeted therapeutic strategies for relapsed disease / John F. de Groot & Howard Colman -- Genes, viruses, toxins and vaccines as therapeutic modalities / Tal Shahar, Manish K. Aghi & Zvi Ram -- Drug delivery strategies for glioblastoma / Pin-Yuan Chen, Dali Yin, John Forsayeth & Krystof S. Bankiewicz -- Index.
  • Digital
    editors, Michael J. Keating, Constantine Tam.
    Future Med2012
    Advances in the treatment of B-cell chronic lymphocytic leukemia / Michael J. Keating & Constantine Tam -- Chronic lymphocytic leukemia : diagnosis and clinical staging / Stephen P. Mulligan & Constantine S. Tam -- Genetics in chronic lymphocytic leukemia / Stephan Stilgenbauer & Thorsten Zenz -- To treat or not to treat / Marco Montillo, Alessandra Tedeschi & Enrica Morra -- Chronic lymphocytic leukemia chemotherapy : two decades of progress / Carol Moreno & Emili Montserrat -- Stem cell transplantation / David G. Maloney -- Treatment options for refractory chronic lymphocytic leukemia / Marina Motta & Alessandra Ferrajoli -- Prognostic markers in chronic lymphocytic leukemia / Renata Walewska & David Oscier -- Therapeutic agents in development and future direction / Sarah Mougalian & Susan O'Brien -- Index.
  • Digital
    editors, Giuseppe Saglio, Carmen Fava.
    Future Med2013
    Advances in the treatment of chronic myeloid leukemia / Giuseppe Saglio & Carmen Fava -- Diagnosis and classification of the risk / Gabriele Gugliotta, Fausto Castagnetti, Francesca Palandri, Michele Baccarani & Gianantonio Rosti -- Genetics of chronic myeloid leukemia / Giovanna Rege-Cambrin, Emilia Giugliano & Patrizia Scaravaglio -- Molecular monitoring / Martin C. Müller, Christian Dietz & Benjamin Hanfstein -- Current targeted therapy with tyrosine kinase inhibitors / Massimo Breccia & Giuliana Alimena -- Stem cell transplantation and high-dose chemotherapy / Deena Iskander, Jane F. Apperley & Jirí Pavlu -- Treatment options for tyrosine kinase inhibitor-resistant chronic myeloid leukemia / Stephan Joseph Dorkhom, Hady Ghanem & Elias Jabbour -- Prognostic factors and future direction for chronic myeloid leukemia / David Marin & Antonia Rotolo -- Chronic myeloid leukemia : the possibility of a cure / Manuel Sobrinho-Simões, David M. Ross & Junia V. Melo -- Index.
  • Digital/Print
    David Wallach, Andrew Kovalenko, Marc Feldmann, editors.
    Digital : Springer2011
    Print2011
    Roles of the TNF family in tissue homeostasis and normal development -- Novel aspects of signaling activation by the TNF family: novel aspects of the functions of the TRAFs and cIAPs -- Novel aspects of signaling activation by the TNF: ubiquitin modification of signaling proteins -- Novel aspects of signaling activation by the TNF family: TNF signaling and gene regulatory networks -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: roles of the TNF family in infectious diseases -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: interrelationship of the TNF family and pattern recognition receptor signaling -- Novel aspects of immune regulation by the TNF family -- Control of lymphocyte function and repertoire by the TNF family -- Advances in applying our knowledge to therapy: mechanisms of pathological and therapeutic effects of the TNF family -- Advances in applying our knowledge to therapy: rational design of new means for therapeutic modulation of function of the TNF family -- Roles of the TNF family in neuronal development, function, and pathology -- Cell death mechanisms controlled by the TNF family -- Contributors to abstracts of talks and posters at the 12th TNF Conference -- Abstracts of talks and posters presented at the 12th TNF Conference.
  • Digital
    Fiona Zwald, Marc D. Brown, editors.
    Springer2015
    This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commentary is provided on the emerging role of viruses in transplant dermatology, the management of skin disease secondary to transplant medication, sunscreen use in transplant recipients, the role of revision of immunosuppression, and advances in photodynamic therapy. The latest staging and management criteria for high-risk squamous cell carcinoma and the implications for clinical practice are then analyzed. Finally, the management of other cutaneous malignancies is discussed, covering malignant melanoma, Merkel cell carcinoma, and rarer tumors that also behave aggressively and require special consideration in solid organ transplant patients. Each particular advance is addressed in an individual chapter by leaders in the field. The book both expands current knowledge and complements previous textbooks on the subject.
  • Digital
    Khalil Fattouch, Patrizio Lancellotti, Mani A. Vannan, Giuseppe Speziale, editors.
    Springer2018
  • Digital
    Joseph D. Rosenblatt, Eckhard R. Podack, Glen N. Barber, Augusto Ochoa, editors
    Springer2014
    Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumors.
  • Digital
    Teruhisa Kazui, Shinichi Takamoto, editors.
    Springer2009
  • Digital
    Russell H. Vreeland, editor.
    Springer2012
    Approaches toward the study of halophilic microorganisms in their natural environments : who are they and what are they doing? / Aharon Oren -- Media and conditions for the growth of halophilic and halolerant bacteria and ardchaea / Mark A. Schneegurt -- Taxonomy of halophilic archaea and bacteria / Antonio Ventosa ... [et al.] -- Halophilic viruses / Shereen Sabet -- Microorganisms in evaporites : review of modern geomicrobiology / Tim K. Lowenstein -- Searching for microbes and DNA in ancient halite / Russell H. Vreeland -- DNA replication and repair in halophiles / Adrienne Kish and Jocelyne DiRuggiero -- Gene transfer mechanisms, population genetics/genimics and the evolution of haloarchaea / R. Thane Papke and Scott Chimileski -- Worth your salt : halophiles in education / Bonnie K. Baxter, Jaimi K. Butler and Betsy Kleba -- Halophiles in the public media / Russell H. Vreeland.
  • Digital
    David Abraham ... [et al.], (eds.).
    Springer2010
  • Digital
    edited by Inga D. Neumann, Rainer Landgraf.
    ScienceDirect2008
    Nonapeptides and the evolutionary patterning of sociality / J.L. Goodson -- Sex differences in vasopressin and oxytocin innervation of the brain / G.J. de Vries -- The parvocellular vasopressinergic system and responsiveness of the hypothalamic pituitary adrenal axis during chronic stress / G. Auilera ... [et al.] -- Experimental approaches for the study of oxytocin and vasopressin gene expression in the central nervous system / E.M. Scordalakes, C. Yue and H. Gainer -- Oxytocin knockout mice: a model for studying stress-related and ingestive behaviours / J.A. Amico ... [et al.] -- The role of the vasopressin 1b receptor in aggression and other social behaviours / H.K. Caldwell, S.R. Wersinger and W.S. Young III -- Behavioural studies using temporal and spatial inactivation of the oxytocin receptor / H.-J. Lee ... [et al.] -- New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behavior and control of energy balance / K. Nishimori ... [et al.] -- Regulation of vasopressin release by co-released neurotransmitters: mechanisms of purinergic and adrenergic synergism / C.D. Sladek and Z. Song -- Neuron-glia interactions in the rat supraoptic nucleus / S.H.R. Oliet ... [et al.] -- Dynamic synapses in the hypothalamic-neurohypophyseal system / K.J. Iremonger and J.S. Bains -- Endogenous modulators of synaptic transmission: cannabinoid regulation in the supraoptic nucleus / N.A. McDonald ... [et al.] -- Oxytocin and appetite / G. Leng ... [et al.] -- Neural mechanisms underlying the milk ejection burst and reflex / G.I. Hatton and Y.-F. Wang -- Oxytocin receptor signaling / D. Devost, P. Wrzal and H.H. Zingg -- Neurosteroids are excitatory in supraoptic neurons but inhibitory in the peripheral nervous system: it is all about oxytocin and progesterone receptors / C. Viero and G. Dayanithi -- Oxytocin receptors: ligand binding, signaling and cholesterol dependence / G. Gimpl ... [et al.] -- Opposite effects of oxytocin and vasopressin on the emotional expression of the fear response / D. Viviani and R. Stoop -- Multi-factorial somato-dendritic regulation of phasic spike discharge in vasopressin neurons / C.H. Brown ... [et al.] -- Neurophysiology of supraoptic neurons in C57/BL mice studied in three acute in vitro preparations / R. Sharif-Naeini ... [et al.] -- Effects of oxytocin on GABA signalling in the foetal brain during delivery / R. Khazipov, R. Tyzio and Y. Ben-Ari -- Central vasopressin and oxytocin release: regulation of complex social behaviours / A.H. Veenema and I.D. Neumann -- Interactions between dopamine and oxytocin in the control of sexual behavior / T.A. Baskerville and A.J. Douglas -- Steroidal/neuropeptide interactions in hypothalamus and amygdale related to social anxiety / E. Choleris ... [et al.] -- Functional magnetic resonance imaging and the neurobiology of vasopressin and oxytocin / C.F. Ferris -- Evolution of the arginine vasopressin 1a receptor and implications for mammalian social behaviour / G. Heckel and S. Fink -- Oxytocin, vasopressin and sociality / C.S. Carter ... [et al.] -- Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans / M. Heinrichs and G. Domes -- Chronic stress plasticity in the hypothalamic paraventricular nucleus / J.P. Herman, J. Flak and R. Jankord -- Keeping oxytocin neurons under control during stress in pregnancy / P.J. Brunton and J.A. Russell -- Rapid synapse-specific regulation of hypothalamic magnocellular neurons by glucocorticoids / S. Di and J.G. Tasker -- Vasopressin in the septum: not important versus casually involved in learning and memory - two faces of the same coin? / M. Engelmann -- Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis / M.A. Steiner and C.T. Wotjak -- Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between / S. Israel ... [et al.] -- Oxytocin and experimental therapeutics in autism spectrum disorders / J.A. Bartz and E. Hollander -- Impact of prosocial neuropeptides on human brain function / A. Meyer-Lindenberg -- Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V₁[a], V₁[b], V₂ and OT receptors: research tools and potential therapeutic agents / M. Manning ... [et al.] -- Affinity and efficacy of selective agonists and antagonists for vasopressin and oxytocin receptors: an "easy guide" to receptor pharmacology / B. Chini, M. Manning and G. Guillon -- Prevention of hypoxic brain oedema by the administration of vasopressin receptor antagonist OPC-31260 / A.H. Molnár ... [et al.] -- Characterization of a novel and selective V₁[B] receptor antagonist / M. Craighead ... [et al.] -- Molecular mechanisms of clinical concentrating and diluting disorders / R.W. Schrier -- Action-binding channels / Y. Noda and S. Sasaki -- Opposite potentiality of hypothalamic coexpressed neuropeptides, apelin and vasopressin in maintaining body-fluid homeostasis / C. Llorens-Cortes and F. Moos -- Recent discoveries in vasopressin-regulated aquaporin-2 trafficking / R.A. Fenton and H.B. Moeller -- Pathophysiological role of aquaporin-2 in impaired water excretion / S.-e. Ishikawa ... [et al.] -- Potential utility of aquaporin modulators for therapy of brain disorders / M.C. Papadopoulos and A.S. Verkman.
  • Digital
    Luciano Mastronardi, Takanori Fukushima, Alberto Campione, editors.
    Springer2019
    This volume describes the most relevant and cutting-edge technological news on the complex surgical procedure of acoustic neuroma. The clinical-radiological diagnosis and surgical indications are briefly presented and the surgical technique is illustrated step-by-step: video clips show the latest means of treating these patients. All these indications were prepared by highly experienced experts in the field, based on their personal experience. The new technologies discussed concern e.g. the intraoperative identification and position of the facial nerve, hearing preservation, techniques for dural closure, and the usefulness of laser and ultrasound aspirators. The book also discusses a number of ongoing projects, including those on: diluted papaverine for microvascular protection of cranial nerves, flexible endoscope for IAC control of tumor removal, fluid cement for bone closure, administering aspirin to control residual tumors larger than 7mm, and DTI for preoperative prediction of the position of the facial nerve.
  • Digital
    Gyan Prakash, Takeshi Iwata, editors.
    Springer2017
    This book presents the state of the art in genetic eye research in Asia and the Pacific. Though there has been an explosion of information on genetic eye research in western countries, more than sixty percent of the human genes involved in eye diseases in the Asian and Pacific population remain unknown. However, new efforts and a new awareness have sparked important discussions on the subject, and new plans are being implemented to discover the genes responsible for many eye diseases in the population. The book reviews the latest findings; its content ranges from genetic aspects of human migration to DNA sequence analysis, genome-wide association analysis, and disease phenotypes. The efforts of the Asian Eye Genetic Consortium (AEGC) are also discussed. The book's editors have been instrumental in developing strategies for discovering the new Asian genes involved in many eye diseases. All chapters were written by leading researchers working on Asian eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume I will prove to be a major resource for all researchers, clinicians, clinical researchers, and allied eye health professionals with an interest in eye diseases among the Asian population.
  • Digital/Print
    Alzira Maria Paiva de Almeida, Nilma Cintra Leal, editors.
    Digital : Springer2012
    Print2012
  • Digital
    Fang-Chieh Chou.
    RNA plays critical roles in fundamental biological processes, including transcription, translation, post-transcriptional regulation of genetic expression, and catalysis as enzymes. These critical RNA functions are determined by the structures and dynamics of the RNA molecules. Computational methods might be used to predict the structures and dynamics of RNA. Unfortunately, the prediction accuracies of current computational methods are still inferior compared to experiments. In this dissertation, I discuss recent advances I made in improving and developing computational methods to make accurate predictions on the RNA structures and dynamics. The dissertation contains three individual research projects. In the first part, I present a protocol for Enumerative Real-space Refinement ASsisted by Electron density under Rosetta (ERRASER). ERRASER combined RNA structure prediction algorithm with experimental constraints from crystallography, to correct the pervasive ambiguities in RNA crystal structures. On 24 RNA crystallographic datasets, ERRASER corrects the majority of steric clashes and anomalous backbone geometries, improves the average Rfree by 0.014, resolves functionally important structural discrepancies, and refines low-resolution structures to better match higher resolution structures. In the second part, I present HelixMC, a package for simulating kilobase-length double-stranded DNA and RNA (dsDNA and dsRNA) under external forces and torques, which is typical in single-molecule tweezers experiments. It recovered the experimental bending persistence length of dsRNA within the error of the simulations and accurately predicted that dsRNA's "spring-like" conformation would give a two-fold decrease of stretch modulus relative to dsDNA. In the third part, I developed a framework of Reweighting of Energy-function Collection with Conformational Ensemble Sampling (RECCES), to predict the folding free energies of RNA duplexes. With efficient sampling and reweighting, RECCES allows comprehensive exploration of the prediction power of Rosetta energy function, and provides a powerful platform for testing future improvement of the energy function. In all the projects above, I leveraged rich datasets from previous experiments to develop novel algorithms that gave predictions with unprecedented accuracies, which were validated by independent blind tests. These computational methods I developed could also serve as a solid foundation for future efforts of improving prediction accuracies of RNA computational algorithms.
  • Digital
    Sergey D. Stavisky.
    The frontier challenges that must be solved before brain-machine interfaces (BMIs) can be used as clinically useful motor prostheses differ depending on the degree of function being restored. Two-dimensional cursor control (i.e., for communication) has recently reached high levels of peak performance in pre-clinical studies, but translation is hampered by less than reliable performance due to unstable neural signals. Meanwhile, control of robotic arms remains poor, despite some impressive glimpses at what the future could be, because we lack fundamental understanding of how the brain incorporates the BMI into its motor schema. This hampers our ability to accurately decode intended arm movements. My dissertation focused on both sets of problems in pre-clinical macaque BMI studies. Chapters 2 and 3 provide solutions for improving BMI robustness. I first describe a machine learning approach to building decoder algorithms that are robust to the changing neural-to-kinematic mappings that plague translational BMI efforts. We developed a multiplicative recurrent neural network decoder that could exploit the large quantities of data generated by a chronic BMI — data that has heretofore gone unused. I then describe a neural engineering approach for increasing the device lifespan by providing high performance control even after losing spike signals. I developed a method for decoding local field potentials (LFPs) as a longer-lasting alternative or complimentary BMI control signal. This led to the highest-performing LFP-driven BMI and the first 'hybrid' BMI which decoded kinematics from spikes and LFPs together. Chapter 4 looks ahead to challenges that will be encountered when BMI-controlled limbs operate in the physical world by describing how error signals impact ongoing BMI control. I perturbing the kinematics of monkeys performing a BMI cursor task and found that visual feedback drove responses starting 70 ms later in the same motor cortical population driving the BMI. However, this initial response did not cause unwanted BMI output because it was limited to a decoder null space in which activity does not affect the BMI. When activity changed in output-potent dimensions starting 115 ms after perturbation, it caused corrective BMI movement. This elegant arrangement may hint at a broader computational strategy by which error processing is separated from output.
  • Digital
    Clarence Y. Cheng.
    RNAs are an essential and versatile category of biopolymers, fulfilling roles from relaying genetic information to catalysis to regulation of gene expression. The formation of and interconversion between conformational states is crucial to the biological functions of RNAs. Chemical mapping methods have proven valuable in providing solution-state, per-nucleotide structural information for RNAs, and computational prediction methods, which can incorporate chemical mapping data, have permitted modeling of both secondary and tertiary RNA structures. However, certain techniques have faced limitations: high-confidence secondary structure prediction through '2D' chemical mapping of systematic mutants (mutate-and-map, M2) is limited by RNA size, and tertiary structure inference through analysis of spatially localized hydroxyl radicals (multiplexed •OH cleavage analysis with gel electrophoresis, MOHCA-gel) is limited by imprecise readouts of proximal residue pairs. Next-generation sequencing (NGS) has greatly enhanced the throughput of chemical mapping, allowing for estimation of chemical reactivities for viral genomes and cellular transcriptomes, but has not yet been leveraged to alleviate the limitations on M2 and MOHCA. In this dissertation, I present the application of NGS readouts to advance a multidimensional chemical mapping (MCM) pipeline for probing and modeling RNA secondary and tertiary structure. First, I demonstrate that a sequencing-based MOHCA-seq method allows for precise detection of tertiary proximities throughout target non-coding RNA (ncRNA) domains. Using constraints from MOHCA-seq data improves Rosetta modeling with experimentally inferred secondary structures to 1-nm accuracy, which allows both visualization of complex ncRNA states, such as the ligand-free states of cyclic-di-GMP, glycine, and adenosylcobalamin riboswitch aptamers, and blind structure predictions of a 188-nt lariat capping ribozyme and a Hox internal ribosome entry site domain. Second, I apply MCM to a bioengineered, directionally switchable RNA-protein motor and demonstrate that it is able to detect distinct sets of tertiary proximities in alternative conformations of a multistate RNA system. Finally, I show that the length and throughput limits of M2 can be overcome by deriving 2D data from high-modification mutational profiling experiments, which permit readout of multiple modifications in single RNA molecules, and explore the basis of the 2D signal. These results improve the applicability and usability of the MCM pipeline and enable structural characterization of previously intractable RNAs.
  • Digital
    Tracy Davis, Laura M. Harrison ; foreword by Larry D. Roper.
    ProQuest Ebook Central2013Limited to 1 simultaneous users
  • Print
    Davis, Tracy; Harrison, Laura M.
    Status: Not Checked Out
  • Digital
    Omer Mei-Dan, Michael R. Carmont, editors.
    Springer2013
    1. The Management of the Extreme Sports Athlete / Omer Mei-Dan and Michael R. Carmont -- 2. Rock and Ice Climbing / Volker Schöffl -- 3. Alpine Skiing and Snowboarding Injuries / Mike Langran -- 4. Skydiving / Anton Westman -- 5. BASE Jumping / Omer Mei-Dan -- 6. Whitewater Canoeing and Rafting / Jonathan P. Folland and Kate Strachan -- 7. Surfing Injuries / Andrew T. Nathanson -- 8. Kite Surfing and Snow Kiting / Mark Tauber and Philipp Moroder -- 9. Windsurfing / Daryl A. Rosenbaum and Bree Simmons -- 10. Sailing and Yachting / Michael R. Carmont -- 11. Mountain Biking Injuries / Michael R. Carmont -- 12. Paragliding / Lior Laver and Omer Mei-Dan -- 13. Mountain, Sky, and Endurance Running / Denise Park and Michael R. Carmont -- 14. Personality Characteristics in Extreme Sports Athletes: Morbidity and Mortality in Mountaineering and BASE Jumping / Erik Monasterio -- 15. Endocrine Aspects and Responses to Extreme Sports / Karen Tordjman, Naama Constantini, and Anthony C. Hackney -- 16. Preventing Injuries in Extreme Sports Athletes / John Nyland and Yee Han Dave Lee -- 17. Rehabilitation of Extreme Sports Injuries / Peter Malliaras, Dylan Morrissey, and Nick Antoniou.
  • Digital
    volume editor, Lars E. French.
    Karger2012
    "The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1 to 5 percent for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists." -- publisher's site.
  • Digital
    Esen Özkaya, Kurtuluş Didem Yazganoğlu.
    Springer2014
    This book describes adverse cutaneous drug reactions as among the most frequent events in patients receiving drug therapy. Cardiovascular drugs are an important group as there are a greater number of indications for the use of new drugs and their prescription continues to increase. The exact incidence of cutaneous side effects from cardiovascular drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable connection between a certain drug and a certain type of reaction can only rarely be made, aside from the well-known angioedema/urticaria from angiotensin-converting enzyme inhibitors, lichen planus/lichenoid reaction from beta adrenergic blockers, and photosensitivity from thiazid diuretics. These reactions can extend to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis and drug hypersensitivity syndrome. Adverse Cutaneous Drug Reactions To Cardiovascular Drugs reviews the reported types of reactions to cardiovascular drugs. Each is discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis. A total of 116 images are included featuring clinical appearance of common adverse cutaneous drug reactions and diagnostic procedures such as patch and photopatch testing with the suspected drugs. Complementary tables may allow to scan the most common cutaneous reactions and the related cardiovascular drugs along with the possible cross reactions at first glance. It will thus be of considerable importance to all dermatologists and medical professionals who manage the skin, while being an important reference resource for cardiologists in terms of identifying potential adverse reactions to the drugs they prescribe.
  • Digital
    Jack Uetrecht, editor.
    Springer2010
    Pt. 1. Target organ toxicity. -- Drug-induced liver injury / Michael Holt, Cynthia Ju.-- Drug herpersensitivity reactions involving skin / Oliver Hausmann, Benno Schnyder, Werner J. Pichler.-- Adverse drug reactions affecting blood cells / Richard H. Aster.-- Molecular mechanisms of adverse drug reactions in cardiac tissue / Reza Tabrizchi.-- Mechanisms of drug-induced nephrotoxicity / Thomas D. Nolin, Jonathan Himmelfarb.-- Receptor- and reactive intermediate-mediated mechanisms of teratogenesis / Peter G. Wells, Crystal J.J. Lee, Gordon P. McCallum, Julia Perstin, Patricia A. Harper.-- Pt. II. Mediators/Biochemical pathways.-- Role of reactive metabolites in drug-induced hepatotoxicity / A.M. Srivastava, J. L. Maggs, D. J. Antoine, D. P. Williams, D. A. Smith, B. K. Park.-- Role of cytokines in the mechanism of adverse drug reactions / Mary Jane Masson, Lindsay A. Collins, Lance R. Poh.-- Keap1-Nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity / Ian M. Copple, Christopher E. Goldring, Neil R. Kitteringham, B. Kevin Park.-- Signal transduction pathways involved in drug-induced liver injury / Derick Han, Mie Shinohara, Maria D. Ybanez, Behnam Saberi, Neil Kaplowitz.-- Mictrochondrial involvement in drug-induced liver injury / Dominique Pessayre, Abdellah Mansouri, Alain Berson, Bernard Fromenty.-- Pt. III. Examples/Models.-- Mechanisms of acetaminophen-induced liver necrosis / Jack A. Hinson, Dean W. Roberts, Laura P. James.-- Drug-induced liver injury in humans: the case of Ximelagtran / M. Keisu, T.B. Andersson.-- Troglitazone / Tsuyoshi Yokoi.-- Neviropine hypersensitivity / M. Popovic, J.M. Shenton, J. Chen, A. Baban, T. Tharmanathan, B. Mannargudi, D. Abdulla, J.P. Uetrecht.-- Mechanisms of adverse drug reactions to biologics / Janet B. Clarke.-- Pt. IV. Risk factors/Screening drug candidates.-- Pharmacogenetics of idiosyncratic adverse drug reactions / Munir Pirmohamed.-- Danger hypothesis applied to idiosyncratic drug reactions / Jinze Li, Jack P. Uetrecht.-- Approaches for minimizing metabolic activation of new drug candidates in drug discovery / Sanjeev Kumar, Kaushik Mitra, Kelem Kassahun, Thomas A. Baillie.
  • Digital
    edited by Bengt Fadeel, Antonio Pietroiusti, Anna A. Shvedova.
    ScienceDirect2012
    A. Engineered nanomaterials: hazard, exposure and safety assessment. Interactions with the human body / Renato Colognato ... [et al.] -- Exposure assessment / Antonio Bergamaschi, Ivo Iavicoli and Kai Savolainen -- Biomonitoring / Enrico bergamaschi and Andrea Magrini -- Critical evaluation of toxicity tests / Maria Dusinska ... [et al.] -- Computational approaches / Vidana Epa, Dave Winkler and Lang Tran -- Regulation and legislation / Maureen R. Gwinn and Birgit Sokull-Klüttgen -- B. Engineered nanomaterials: impact on human health. Respiratory system / Ken Donaldson and Craig Poland -- Cardiovascular system / Jennifer B. Raftis, Nicholas L. Mills and Rodger Duffin -- Neurological system / Sandra Ceccatelli and Giuseppe Bardi -- Immune system / Diana Boraschi and Albert Duschl -- Skin / Nancy A. Monteiro-Riviere and Francesca Larese Filon -- Gastrointestinal tract / Mark A. Jepson -- Reproductive toxicity / Karin Sørig Hougaard and Luisa Campagnolo -- Genotocicity and cancer / Shareen H. Doak, Ying Liu and Chunying Chen -- C. Biomedical applications of engineered nanomaterials. Diagnostic applications / Kalcheng and Zhen Cheng -- Therapeutic applications / Cyrill Bussy ... [et al.] -- Annex: synthesis of engineered nanomaterials / Muhammet S. toprak, Gulaim A. Seisenbaeva and Vadim G. Kessler.
  • Digital
    edited by Bengt Fadeel, Antonio Pietroiusti, Anna A. Shvedova.
    ScienceDirect2017
    Bio-nano interactions / Dana Westmeier, Shirley K. Knauer, Roland H. Stauber, Dominic Docter -- Physicochemical characterization / Kristen Rasmussen, Hubert Rauscher, Agnieszka Mech -- Toxicity tests / Maria Dusinska, Elise Rundén-Pran, Jürgen Schnekenburger, Jun Kanno -- Computational approaches / Tu C. Le, Vidana Epa, Lang Tran, Dave Winkler -- Exposure Assessment / Kai Savolainen, Antonio Pietroiusti -- Biomonitoring / Enrico Bergamaschi, Irirna Guseva Canu, Adriele Prina-Mello, Regulation and legislation / Kirsten Rasmussen, Brigit Sokull-Klüttgen, IL Je Yu, Jun Kanno, Akihiro Hirose, Maureen R. Gwinn -- Risk assessment and risk management / Robert Landsiedel, Ursula G. Sauer, Wim H De Jong -- Respiratory system, part one / Craig A. Plooand, Ken Donaldson -- Respiratory system, part two / Harri Alenius, Michael R. Shurin, Galina V. Shurin, Don Beezhold, Anna A. Shvedova -- Cardiovascular system / Jennifer B. Raftis, Nicholas L. Mills, Rodger Duffin -- Neurological system / Myrtill Simkó, Mats-olof Mattsson, Robert A. Yokel -- Immune system / Diana Boraschi, Bengt Fadeel, Albert Duschl -- Endorine system / Xuefei Lu, Yong Zhu, Tao Zhu -- Skin / Nancy A. Monteiro-Riviere, Francesca Larese Filon -- Gastrointestinal system / Mark A. Jepson, Hans Bouwmeester -- Reproduction and development / Luisa Campagnolo, Karin S. Hougard -- Genotoxicitiy and cancer / Shareen H. Doak, Ying Liu, Chunying Chen.
  • Digital
    Giuseppe Tridente.
    ScienceDirect2017
    Introduction -- Kinases -- Kinase inhibitors -- Adverse events -- Imantinib -- Gefitinib -- Erlotinib -- Sorafenib -- Sunitinib -- Dasatinib -- Lapatinib -- Nilotinib -- Pazopanib -- Vandetanib -- Vemurafenib -- Crizotinib -- Ruxolitinib -- Axitinib -- Bosutinib -- Regorafenib -- Cabozantinib -- Ponatinib -- Dabrafenib -- Trametinib -- Afatinib -- Idelaisib -- Ibrutinib -- Overview -- Conclusion and perspectives.
  • Digital
    Giuseppe Tridente.
    Springer2014
    This monograph gathers and evaluates data on adverse events (AEs) associated specifically with those 'biomedicines' - monoclonal antibodies, fusion proteins, and cytokines - that have recently entered therapeutic use in humans. All AEs observed when using each member of this new drug class are covered, with a view to improving understanding of pathogenesis, facilitating prevention, monitoring, and control, and contributing to the development of better drugs that provide benefits while minimizing risk. Further aspects here examined include the role of drug mechanisms of action and immunogenicity in relation to AEs outcome and induction of systemic syndromes. Additional data on AEs in off-label treatments are also considered. Electronic data sheets, downloadable from the Springer Extra Materials platform, include more detailed safety data as well as additional basic information on product characteristics, pre- and post-marketing AEs classified according to frequency, and system/organ targeting. Data on excipients and selected information on drug interactions and associations are also provided. Adverse Events with Biomedicines: Prevention Through Understanding will serve as a detailed, practical guideline to this important new area, which demands the attention of clinicians, immunologists, oncologists, allergologists, public health professionals, and drug companies.
  • Digital
    volume editors, Lluís Puig, Wayne Gulliver.
    Karger2018
    Adverse reactions to biologics in psoriasis / Lockwood, S.J., Prens, L.M.; Kimball, A.B. -- Clinical trial and registry data / Gooderham, M., Papp, K. -- Immunosuppression/infections across indications / Al-Khalili, A., Dutz, J.P. -- The immunogenicity of biologic therapies / Garcias, S., Demengeot, J. -- Paradoxical reaction S : anti-tumor necrosis factor alpha agents, Ustekinumab, Secukinumab, Ixekizumab, and others / Puig, L. -- Bullous diseases / Corbaux, C., Joly, P. -- Adverse reactions of antibody-therapy for primary cutaneous lymphomas : Rituximab, Brentuximab vedotin, Alemtuzumab, and Mogamulizumab / Saulite, I., Guenova, E., Hoetzenecker, W. -- Adverse reactions to biologics : melanoma (Ipilimumab, Nivolumab, Pembrolizumab) / Hwang, S.J.E., Fernández-Peñas, P. -- Skin manifestations of targeted antineoplastic therapy / Sanmartín, O.
  • Digital
    Richard Colgan.
    Springer2013
    Part I. Inspirational Perspectives from History -- -- Introduction -- Ancient times -- Chinese and medieval medicine -- The twentieth century -- Modern masters -- -- Part II. Practical Advice for the Modern-Day Healer -- -- Survival tips for the younger clinician -- Civility -- Lessons learned from private practice -- A doctor's journal -- Heal thyself -- The healer.
  • Digital
    Richard Colgan.
    Springer2009
  • Digital
  • Digital
    edited by Devanand Sarkar and Paul B. Fisher.
    ScienceDirect2013
    Ch. 1. AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression -- Ch. 2. AEG-1/MTDH/LYRIC: clinical significance -- Ch. 3. AEG-1/MTDH/LYRIC: signaling pathways, downstream genes, interacting proteins, and regulation of tumor angiogenesis -- Ch. 4. Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer -- Ch. 5. Drug resistance mediated by AEG-1/MTDH/LYRIC -- Ch. 6. The role of AEG-1/MTDH/LYRIC in the pathogenesis of central nervous system disease -- Ch. 7. AEG-1/MTDH/LYRIC in liver cancer -- Index.
  • Digital
    edited by William W. Hurd, William Beninati.
    Springer2019
    Now in its fully revised and expanded second edition, this volume is the definitive resource on long-distance air transport of injured patients in both peacetime and wartime. It discusses the history of aeromedical evacuation, triage and staging of the injured patient, evacuation from site of injury to medical facility, air-frame capabilities, medical capabilities in- flight, response to in-flight emergencies, and mass emergency evacuation. Specific medical conditions are addressed in detail in the second half of the book, including general surgical casualties such as abdominal wounds and soft tissue injuries, vascular injuries, maxillofacial injuries, head and spinal cord injuries, ophthalmologic casualties, orthopedic casualties, burns, pediatric casualties, obstetric-gynecologic casualties, and more. For each medical condition, important topics are addressed such as conditions needed to be met before transportation, special concerns, supplies and needs of the specific patients and possible in-flight emergencies and their appropriated treatment. Containing several new chapters and featuring extensively updated contributions from experts in the field, Aeromedical Evacuation: Management of the Acute and Stabilized Patient, Second Edition is a must-have reference for a whole new generation of military flight surgeons and flight nurses responsible for aeromedical evacuation of casualties as well as civilian physicians and nurses involved in air transport of ill and post-operative patients. .
  • Digital
    Stefan Gress.
    Springer2017
    Introduction -- Anatomy and Function -- The?Perfect Look? -- Indications -- Labia minora: Planning the Procedure -- Surgical Techniques -- Pitfalls & Complications -- Aftercare. Labia majora: Planning the Procedure -- Surgical Technique -- Pitfalls & Complications -- Aftercare -- Before surgery -- Aftercare -- Consent -- FAQs.
  • Digital
    editors, Elizabeth J. Hall-Findlay, Gregory R.D. Evans ; video editor, Kenneth K. Kim.
    ScienceDirect2010
    ClinicalKey2010
    Drs. Hall-Findlay and Evans' new Aesthetic and Reconstructive Surgery of the Breast has a purely surgical focus that covers the full scope of breast surgery. Coverage of hot topics includes new implant types, gel implants, fat injections to the breast for aesthetic enhancement, and fat injections for reconstruction. The book is organized into seven sections including reduction, mastopexy, augmentation, and more. Expert, international contributors deliver practical advice on the latest techniques, with a special emphasis on what can go wrong and how to avoid it. This full-color, templated reference comes with case studies and 16 video clips (both on web and on DVD) with approximately three hours of footage demonstrating key procedures. Video coverage includes form-stable high cohesive silicone gel implants, short scar with inferior pedicle, and sub-fascial breast augmentation. Expert Consult access enables you to search full text online and download images. Get practical advice on handling problems that occur in both reconstructive and aesthetic surgery Study various operative steps in depth with real-life clinical detail Avoid and/or deal with complications by referencing case examples and analyses with expert international counsel Watch the techniques first-hand with videos online and on the accompanying DVD, and watch experts performing the procedures Search the text's full content electronically, or download images and video for teaching purposes.
  • Digital
    Lucian Fodor, Yehuda Ullmann, Monica Elman.
    Springer2011
    Skin anatomy -- Light tissue interactions -- Intense pulsed light safety: legal issues -- How to organize the IPL treatment room -- Patient selection -- Skin photorejuvenation -- Hair removal -- IPL treatment for vascular lesions -- Complications.
  • Digital
  • Digital
    [edited by] Marian Cantisano-Zilkha, Alessandra Haddad.
    ClinicalKey2010
    Overview of the aesthetic approach -- Combining non-invasive therapies -- Skincare -- Chemical peels -- Lasers and intense light sources -- Photodynamic treatment -- Skin tightening devices -- Botulinum toxin for oculofacial aesthetic rejuvenation -- Facial fillers and volumizers -- Fat transfer -- Dark circles: a combination approach -- Minimally invasive laser lipolysis for facial and neck rejuvenation -- Mesotherapy -- Carbon dioxide therapy: face and body rejuvenation -- Cosmetic dentistry of the perioral area: the odontological point of view -- Importance of aesthetician in a cosmetic practice -- From the inside out: a psychotherapist's views on aesthetic enhancement -- Future of oculofacial rejuvenation: a perspective.
  • Digital
    [edited by] Sherell J. Aston, Douglas S. Steinbrech, Jennifer L. Walden.
    ClinicalKey2009
    Office practice of plastic surgery -- Clinical photography for the aesthetic patient -- Anesthesia in aesthetic surgery -- Postoperative nausea and vomiting -- Patient safety in aesthetic surgery -- Facelift anatomy, SMAS, retaining ligaments and facial spaces -- Facelift with SMAS technique and FAME -- Facelift with SMAS technique and FAME -- Short scar facelift -- Foundation facelift -- The "High SMAS" facelift technique -- MACS facelift -- The multi-vectored rhytidoplasty -- The male facelift -- Endoscopic mid and lower face rejuvenation -- Endoscopic facial rejuvenation -- Facial rejuvenation in non-Caucasians -- Aesthetic facial microsurgery -- Midface lift -- Deep plane procedures in the neck -- Treatment of the male neck -- Managing submandibular glands -- Non-endoscopic limited incision browlift -- Coronal browlift -- Endoscopic browlift with internal fixation -- Transblepharoplasty browlift -- Suture suspension for face and neck -- Suture suspension for brow and upper face -- Conventional upper and lower blepharoplasty -- Lateral canthal suspension techniques -- Lid-cheek blending: the tear trough deformity -- Tarsal strip canthoplasty -- Blepharoplasty in the East Asian patient -- Treatment of blepharoplasty complications -- Autologous contouring the lower face -- Alloplastic chin augmentation -- Primary closed rhinoplasty -- Primary open rhinoplasty -- Secondary rhinoplasty -- Nasal tip grafting with an "anatomic tip graft" and sizers -- Nasal tip grafting with an "anatomic tip graft" and sizers -- Correction of the deviated septum -- The ethnic rhinoplasty -- The Asian rhinoplasty -- Correcting the cleft lip nose -- Primary otoplasty and reconstruction -- Traditional inverted-T breast reduction -- Mastopexy with and without augmentation -- Pitanguy breast reduction -- Medial pedicle vertical mammaplasty -- Periareolar Benelli mastopexy and reduction: The "Round Block" -- Breast implants: background, safety and general considerations -- Breast augmentation -- The dual plane approach to breast augmentation -- Cohesive gel breast augmentation -- Difficult breast augmentations -- Breast reconstruction -- Nipple - areola reconstruction -- Pure aspiration lipoplasty -- Complications and corrections of lipoplasty -- New concepts in fat grafting -- Lipoabdominoplasty: Saldanha's technique -- Lipoabdominoplasty: Advanced techniques and technologies -- Non-surgical ultrasonic lipoplasty -- Ultrasound assisted liposuction -- Abdominoplasty techniques -- Brachioplasty -- Belt lipectomy: Lower body lift -- High lateral tension abdominoplasty -- Gluteal augmentation -- Botox® for face, neck and brow -- Lip augmentation -- Structural fat augmentation of the face and hands -- Hyaluronic acid injectable filler -- Non-hyaluronic acid fillers for facial augmentation -- Laser resurfacing -- Fractional resurfacing -- Total facial alloplastic augmentation -- Chemical peels and dermabrasion.
  • Digital
    Alberto Di Giuseppe, Melvin A. Shiffman, editors.
    Springer2016
    This comprehensive book covers anatomy, recent techniques, postoperative care, possible complications, and outcomes in aesthetic surgery of the abdomen. The extensive section on aesthetic procedures includes many important innovations in abdominoplasty. Detailed consideration is also given to the various potential complications, with guidance on their prevention, diagnosis, and management. The book is written by acknowledged experts in the topics on which they write. It will be of value for residents and fellows and more experienced surgeons in the fields of plastic surgery, general surgery, cosmetic surgery, and general surgery.
  • Digital
    [edited by] Hong Ryul Jin.
    Thieme-Connect2016
  • Digital
    [edited by] Bahman Guyuron, Brian M. Kinney.
    ClinicalKey2012
    Patient Assessment -- Skin Care Including Chemical Peeling -- Non-surgical Facial Rejuventation with Fillers -- Botulinum Toxin -- Laser Facial Resurfacing and Dermabrasion -- Management of Alopecia -- Forehead Rejuvenation -- Periorbital Rejuvenation -- Facelift with SMAS Flaps -- Neck Rejuvenation -- Primary Rhinoplasty -- Secondary Rhinoplasty -- Genioplasty -- Aesthetic Contouring of the Craniofacial Skeleton -- Augmentation of Facial Structures with Autologous Fat -- Breast Augmentation -- Breast Reduction -- Mastopexy -- Liposculpture -- Abdominoplasty -- Bodylifts and Post Massive Weight Loss Body Contouring -- Surgical Management of Migraine Headaches.
  • Digital
    Bariş Çakir.
    Springer2016
  • Digital
    Toma T. Mugea, Melvin A. Shiffman, editors.
    Springer2015
    This book covers all aspects of aesthetic breast surgery in an instructive, step-by-step format. The descriptions of procedures are completely up to date, encompassing newly introduced techniques and recent modifications of established techniques. Individual parts of the book are devoted to breast augmentation, mastopexy, and breast reduction. Detailed consideration is also given to risks and complications, with guidance on their avoidance and the treatment of complications. In addition, anatomy, anesthesia, and a range of miscellaneous procedures applicable in specific circumstances are all well covered. The authors are acknowledged experts in their fields who draw on a wealth of experience in describing and illustrating their personally favored techniques. Aesthetic Surgery of the Breast will be an ideal reference for both students (residents and fellows) and practicing cosmetic, plastic, and general surgeons.
  • Digital
    [edited by] James D. Frame, Shahrokh C. Bagheri, David J. Smith, Husain Ali Khan.
    ClinicalKey2019
    "Changing trends, ethnic and regional preferences, and a hands-on teaching method make cosmetic surgery uniquely challenging for novice and experienced surgeons alike. Aesthetic Surgery Techniques: A Case-Based Approach offers expert, real-world instruction by presenting chapters and patients in a classical fashion, providing a clinical perspective as you work through case after case, honing your knowledge and skills. A diverse, international group of highly reputable faculty takes you step by step through each case"--Publisher's description.
  • Digital
    [edited by] Pearl E. Grimes ; associate editors, Teresa Soriano, Doris M. Hexsel, Jenny Kim.
    Ovid2008
  • Digital
    volume editor, Rainer Staudenmaier.
    Karger2010
    History of auricular reconstruction / Weerda, H. -- State-of-the-art autogenous ear reconstruction in cases of microtia / Firmin, F. -- Ear reconstruction with porous polyethylene implants / Berghaus, A. ... [et al.] -- Auricular prostheses / Federspil, P.A. -- Combined aesthetic and functional reconstruction of ear malformations / Kiefer, J., Staudenmaier, R. -- Combined reconstruction of congenital auricular atresia and severe microtia / Siegert, R. -- Ear reconstruction through tissue engineering / Haisch, A. -- Customized tissue engineering for ear reconstruction / Staudenmaier, R. ... [et al.].
  • Digital
    P. Colm Malone, Paul S. Agutter.
    Springer2008
  • Digital
    edited by Senta Reichelt, Leibniz-Institut für Oberflächenmodifizierung, Leipzig, Germany.
    Springer2015
    Affinity chromatography : a historical perspective -- Protein purification by amniosquarylium cyanine dye-affinity chromatography -- One-step purification of phosphinothricin acetyltransferase using reactive dye-affinity chromatography -- Antibody purification from human plasma by metal-chelated affinity membranes -- Specific recognition of supercoiled plasmid DNA by affinity chromatography using a synthetic aromatic ligand -- Cell affinity separations on microfluidic devices -- Aptamer-modified magnetic beads in affinity separation of proteins -- The Strep-tag system for one-step affinity purification of proteins from mammalian cell culture -- Robotic high-throughput purification of affinity-tagged recombinant proteins -- Macroporous silica particles derivatized for enhanced lectin affinity enrichment of glycoproteins -- Immobilized magnetic beads-based multi-target affinity selection coupled with HPLC-MS for screening active compounds from traditional Chinese medicine and natural products -- Mixed-bed affinity chromatography : principles and methods -- Preparation and characterization of fluorophenylboronic acid-functionalized affinity monolithic columns for the selective enrichment of cis-diol-containing biomolecules -- Introduction to macroporous cryogels -- Cryogels with affinity ligands as tools in protein purification -- Direct capture of His₆-tagged proteins using megaporous cryogels developed for metal-ion affinity chromatography -- Ni(II) chelated IDA functionalized poly(HEMA-GMA) cryogels for urease adsorption -- A novel chromatographic media : histidine-containing composite cryogels for HIgG separation from human serum -- Molecularity imprinted cryogels for human serum albumin depletion -- Interpenetrating polymer network composite cryogels with tailored porous morphology and sorption properties -- Analysis of drug-protein interactions by high-performance affinity chromatography : interactions of sulfonylurea drugs with normal and glycated human serum albumin -- Accurate protein-peptide titration experiments by nuclear magnetic resonance using low-volume samples -- Characterization of the binding strengths between boronic acids and cis-diol-containing biomolecules by affinity capillary electrophoresis -- Determination if the kinetic rate constant of cyclodextrin supramolecular systems by high-performance affinity chromatography -- Molecular modeling of the affinity chromatography of monoclonal antibodies.
  • Digital
    edited by Misty M. Ginicola, Cheri Smith, Joel M. Filmore.
    Wiley2017
    Preface -- About the editors -- About the contributors -- Acknowledgments -- Foundations -- Developing competence in working with LGBTQI+ communities : awareness, knowledge, skills, and action / Misty M. Ginicola, Joel M. Filmore, and Cheri Smith -- The science of gender and affectional orientation / Misty M. Ginicola -- Counseling considerations and counseling strategies -- Developmental issues for LGBTQI+ people -- Growing up LGBTQI+ : the importance of developmental conceptualizations / Anneliese A. Singh, Kristopher M. Goodrich, Amney J. Harper, and Melissa Luke -- LGBTQI+ youth development / Melissa Luke, Amney J. Harper, Kristopher M. Goodrich, and Anneliese A. Singh -- LGBTQI+ persons in adulthood / Amy Moore-Ramirez, Melanie Kautzman-East, and Misty M. Ginicola -- Identity development, coming out, and family adjustment / Kristopher M. Goodrich and Misty M. Ginicola -- Physical and mental health challenges found in the LGBTQI+ population / Misty M. Ginicola, Joel M. Filmore, Cheri Smith, and Jahaan Abdullah -- Disaffirming therapy : the ascent and descent of sexual orientation change efforts / Peter Finnerty, Michael M. Kocet, Jeff Lutes, and Chad Yates -- Evidence based practice for counseling the lgbtqi+ population / Kristopher M. Goodrich and Misty M. Ginicola -- Affirmative, strength-based counseling with LGBTQI+ people / Peter Finnerty, Michael M. Kocet, Jeff Lutes, and Chad Yates -- Specialized populations -- Counseling lesbian clients / Cindy Anderton and Lindsay Woodbridge -- Counseling gay male clients / Misty M. Ginicola, Sam Sanabria, Joel M. Filmore, and Michael DeVoll -- Counseling bisexual/pansexual/polysexual clients / Misty M. Ginicola and Amney J. Harper -- Counseling transgender clients / Robyn Brammer and Misty M. Ginicola -- Counseling queer and genderqueer clients / Jeffry Moe, Jamie Bower, and Madeline Clark -- Counseling clients questioning their affectional orientation / Jared S. Rose and Eric R. Baltrinic -- Counseling intersex clients / Misty M. Ginicola -- Counseling asexual clients / Misty M. Ginicola and Angela Ruggiero -- Counseling two-spirit clients / Misty M. Ginicola -- Emerging issues -- Role of ethnicity -- Counseling a LGBTQI+ person of color / Joel M. Filmore and Misty M. Ginicola -- Counseling LGBTQI+ immigrants / David Barreto, Amy Moore-Ramirez, Melanie Kautzman-East, and Ryan Liberati -- Role of religion -- The role of religion and spirituality in counseling the LGBTQI+ client / Misty M. Ginicola, Brett H. Furth and Cheri Smith -- The grace model of counseling : navigating intersections of affectional orientation and Christian spirituality / R. Lewis Bozard, Jr., and Cody J. Sanders -- Working with LGBTQI+ clients who have experienced religious and spiritual abuse using a trauma informed approach / Misty M. Ginicola, Joel M. Filmore, and Michael Stokes -- Counselor advocacy -- Becoming an ally : personal, clinical, and school-based social justice interventions / Diane Estrada, Anneliese A. Singh, and Amney J. Harper -- Glossary of terms.
  • Digital
    Aron Janssen, Scott Leibowitz, editors.
    Springer2018
    This unique resource offers an in-depth, comprehensive look at different types of mental health needs of transgender and gender diverse youth, how these intersect with gender identity, gender expression, and sexual orientation, and provides practical information on how to ethically, responsibly, and sensitively care for these patients. Affirmative Mental Health Care for Transgender and Gender Diverse Youth: A Clinical Guide begins with three introductory chapters which contain practical information regarding assessment, psychological interventions, and the potential medical and surgical interventions that are indicated for youth with gender identity concerns. The remaining chapters are illustrated by multiple cases build around overarching chapter themes. Each case chapter opens with broad questions applicable to clinical practices, while the cases themselves focus on a particular co-occuring mental health condition. The case chapters are structured with intersectionality in mind, including elements of ethnic, racial, and cultural diversity, and the patients range over the full developmental spectrum, from pre-pubertal children to older adolescents. Chapter cases range in complexity as well, to provide readers with the tools they need to evaluate patients, and to assist in the decision of which presenting factors to prioritize in treatment at which time. Ending each chapter are clinical take-home messages, closing with additional practical knowledge that can be applied to other cases providers may see in their own practices. Written by expert clinicians in the field, Affirmative Mental Health Care for Transgender and Gender Diverse Youth: A Clinical Guide is an ideal resource not only for child and adolescent psychiatrists, but for clinicians across all mental health disciplines working with gender non-conforming youth, and who are interested in providing informed, affirmative, and intersectional care.
  • Digital
    Adelle Simmons, Jessamy Taylor, Kenneth Finegold, Robin Yabroff, Emily Gee, and Andre Chappel.
    The Affordable Care Act promotes better health for women through the law's core tenets of access, affordability, and quality. For example, the law's provisions have expanded coverage through the Health Insurance Marketplaces and Medicaid expansions; made coverage more affordable through premium tax credits and by eliminating gender differences in premiums in the individual and small-group insurance markets; and improved quality of coverage by eliminating lifetime and annual dollar limits on Essential Health Benefits and requiring coverage of recommended preventive services and maternity care. Continued implementation of the Affordable Care Act will play a significant role in promoting the health and well-being of women across the lifespan. This report is organized into three sections that describe how health care access, affordability, and quality of care have improved for women since enactment of the Affordable Care Act.
  • Digital
    Harry P. Selker, June S. Wasser, editors.
    Springer2014
    This book examines the landmark 2010 Patient Protection and Affordable Care Act (ACA) from the perspective that health policy innovation is translational research directed at improving health. It delineates a new perspective about the creation and potential impact of the ACA and guides the development of health policy that is supported by best evidence that, in turn, transforms into practice, policy, and public benefit. Told by those involved in the creation and implementation of the ACA, the book reviews the history and impact of this ground-breaking legislation and recommends priorities, objectives, and next steps for translational research as the ACA is implemented. Featuring contributions from nationally renowned leaders in healthcare policy, this book adds to the public conversation about the ACA and its role in shaping health policy and contributes to a more realistic, nuanced, and productive understanding of this ground-breaking legislation by physicians, policy makers, and the public. It also provides a framework for next steps in continuing to improve U.S. health policy.
  • Digital
    by Kelsey Avery, Kenneth Finegold, and Amelia Whitman.
    Historic gains in health insurance coverage have been achieved since the implementation of the Affordable Care Act (ACA). Individuals and families of all income levels, age groups, races and ethnicities, and urban and rural areas have seen substantial reductions in uninsured rates. Coverage expansion provisions of the ACA (i.e., the Health Insurance Marketplace and Medicaid expansion) and reforms in the private market, such as allowing young adults to remain on their parents' plan until age 26 and requiring insurers to cover individuals with pre-existing health conditions, have worked in concert to reduce the national uninsured rate to a historic low of 8.6 percent. To date, 20 million individuals have gained health coverage as a result of the ACA . This brief, uses new and previously published estimates from the National Health Interview Survey to examine gains in health insurance coverage for non-elderly adults from 2010 to 2015. It also provides estimates of the uninsured rate over time by income, race, state Medicaid expansion status, age, and urban and rural residence (see Appendix Table 2 for additional demographic categories).
  • Digital
    William A. Haseltine.
    The Singapore healthcare system : an overview -- High quality, low cost -- Helping patients pay -- Controlling costs -- Financing -- Design and infrastructure -- Investing in the future through medical education and research -- Facing the future.
  • Digital
    by Janet Viveiros.
    This report examines several ways in which health care changes created by the ACA, and other health care reform initiatives, create the potential for affordable housing providers to collaborate with health care providers, insurers, and other institutions to support the wellbeing of low-income individuals and families.
  • Digital
    Donna Hubbard McCree, Kenneth Terrill Jones, Ann O'Leary, editors.
    Springer2010
    The HIV/AIDS epidemic is burgeoning among African American men and women. Despite comprising only 13 percent of the population, 50 percent of new HIV diagnoses in 2004 were among African Americans. Among women and men who have sex with men (MSM), African Americans are grossly disproportionately affected by this epidemic, and this trend shows no sign of abating. This book seeks to explore some of the contextual factors that contribute to this disparity as well as ways to intervene to slow the growth of the epidemic in the U.S. This volume will focus on the history and context of HIV/AIDS in African Americans and interventions targeting specific subpopulations including adolescents, heterosexual men and women, men who have sex with men, incarcerated populations, and injection drug users. Context chapters will focus on specific contextual and structural issues related to HIV/AIDS transmission and prevention in African Americans including disparities in incarceration, racism, economic issues and substance abuse. Intervention chapters will focus on best-evidence and promising-evidence based interventions targeting HIV prevention in African Americans. These chapters will address the latest in intervention strategies, program evaluation, cost effectiveness and qualitative research methods and will include risk reduction, risk assessment, and testing and counseling.
  • Digital
    edited by Patrick Low, Chiedu Osakwe, Maika Oshikawa.
    Cambridge2016
    Introduction and overview / Patrick Low, Chiedu Osakwe and Maika Oshikawa -- African Union priorities in the WTO / Fatima Haram Acyl -- Economic diversification in Africa's number one economy / Okechukwu E. Enelamah -- Trade, investment and development / Rob Davies -- Integration into regional and global value chains : how is it done? / Joshua Setipa -- From Marrakesh to Nairobi : a force for the world trading system : from the past twenty years to the next twenty years / Moulay Hafid El Alamy -- Building capacity in Africa to facilitate integration into global value chains : contributions from the ITC / Arancha Gonzalez -- Investment and trade rules : increasing the stock of African foreign direct investment flows / Joakim Reiter -- Deepening African integration : intra-African trade for development and poverty reduction / Anabel Gonzalez -- Rising Africa in world trade? A story of traditional commodities and new products / Michael Finger -- Trade policy trends in Africa : empirical evidence from twenty years of WTO trade policy reviews / Maika Oshikawa, Ukamaka Anaedu and Vicky Chemutai -- Preferential trade agreements in Africa : lessons from the tripartite free trade agreements and an African continent-wide FTA / Stephen Karingi, Ottavia Pesce and Simon Mevel -- African trade integration and international production networks / Bernard Hoekman -- Implementing trade facilitation reform in Africa / Marcus Bartley Johns, Christina Busch and Gerard McLinden -- Trade rules, industrial policy and competitiveness : implications for Africa's development / Chiedu Osakwe -- WTO accessions, reforms and competitiveness : lessons for Africa / Alexei P. Kireyev -- Driving economic growth through trade policy reforms and investment attraction in the open world economy : the experience of China / Yuan Yuan -- Conclusions / Patrick Low, Chiedu Osakwe and Maika Oshikawa.
  • Digital/Print
    edited by Angelique Richardson.
    Digital : Brill2013
    Print2013
    1. Love and hatred are common to the whole sensitive creation: animal feeling in the century before Darwin -- 2. 'The Book of the Season': the conception and reception of Darwin's Expression -- 3. The backbone shiver: Darwin and the arts -- 4. Becoming an animal: Darwin and the evolution of sympathy -- 5. George Eliot, G.H. Lewes, and Darwin: animals, emotions, and morals -- 6. Between medicine and evolutionary theory: sympathy and other emotional investments in life writings by and about Charles Darwin -- 7. From entangled vision to ethical engagement: Darwin, affect, and contemporary exhibition projects -- 8. Reckoning with the emotions: neurological responses to the theory of evolution, 1870-1930 -- 9. Darwin's changing Expression and the making of the modern state -- 10. Calling the wild: selection, domestication, and species -- 11. The development of emotional life -- Afterword. The emotional and moral lives of animals: what Darwin would have said -- Index.
  • Digital
    Michael J. Hyde and James A. Herrick, editors.
    ProQuest Ebook Central2013
    Faith in science : professional and public discourse on regenerative medicine / Tristan Keys, Nancy M. P. King, and Anthony Atala -- From Arrowsmith to Atwood : how did we come to disrespect science? / Ronald M. Green -- The "warfare" of science and religion and science's ethical profile / Thomas M. Lessl -- Is there a human nature? : an argument against modern excarnation / Jean Bethke Elshtain -- Crossing frontiers of science : trespassing into a godless space, or, Fulfilling our manifest destiny / Leah Ceccarelli -- The angels and devils of representing Prozac / Tod Chambers -- "Leave your medicine outside" : bioethics, spirituality, and the rhetoric of Appalachian serpent handlers / Bill J. Leonard -- Biovaluable stories and a narrative ethics of reconfigurable bodies / Arthur W. Frank -- Blacks and the language of their biotechnological future / Ezra E. H. Griffith -- Bioethics, economism, and the rhetoric of technological innovation / Howard Brody -- Technologies of the self at the end of life : pastoral power and the rhetoric of advance care planning / Lisa Kernen -- Suffering and the rhetoric of care / Judy Segal.
  • Digital
    DeSilvey, S.
  • Digital
    Philippe Humbert, Ferial Fanian, Howard I. Maibach, Pierre Agache, editors.
    Springer2017
    Since the first edition of this book was published in 2004, to much acclaim, the pace of innovation in the field of skin metrology has increased and various new technologies have become available. This new, revised edition reflects these advances by presenting the current theory and practice of noninvasive investigation and measurement of the skin and its appendices in health and disease. The first, extensive part of this authoritative work is devoted to the physiology and metrology of the various structural components of the skin. Skin functions and their measurement are then discussed in detail, with sections on mechanical protection, photoprotection, barrier function, immune function, thermoregulation, and sensory function. In addition, careful consideration is given to skin disease rating and skin maps, and a unique list of physical and biological constants and units is provided. Not only is this new edition the first comprehensive, practical handbook in this domain – it will also serve as a manual of skin physiology and collates anatomical, functional, and physical quantitative data that would otherwise be arduous to retrieve because of their dispersal throughout the literature. It will prove a valuable resource for dermatologists, cosmetologists, bioengineers, physiologists, pharmacists, and all others who deal with the skin in their work.
  • Print
    Crystal R. Emery.
    Status: Not Checked Out
  • Digital
    David Alfandre, editor.
    Springer2018
    "This first-of-its-kind text provides a multidisciplinary overview of a significant problem in hospital-based healthcare: patients who decline inpatient medical care and leave the hospital against medical advice (AMA). Compared to standard hospital discharges, AMA discharges are associated with worse health and health services outcomes. Patients discharged AMA have been found to have disproportionately higher rates of substance use, psychiatric illness, and report stigmatization and reduced access to care. By providing a far reaching examination of AMA discharges for a wide academic and clinical audience, the book serves as a reference for clinical care, research, and the development of professional guidelines and institutional policy. The book provides both a broad overview of AMA discharges with chapters on the epidemiology, ethical and legal aspects, as well as social science perspectives. For clinicians in the disciplines of hospital medicine, pediatrics, emergency medicine, nursing, and psychiatry, the book also provides a patient-centered analysis of the problem, case-based discussions, and a discussion of best practices. This comprehensive review of AMA discharges and health care quality will interest physicians and other health care professionals, social workers, hospital administrators, quality and risk managers, clinician-educators, and health services researchers."--Back cover.
  • Print
    Allen M. Hornblum, Judith L. Newman, and Gregory J. Dober.
    "The sad history of young children, especially institutionalized children, being used as cheap and available test subjects - the raw material for experimentation - started long before the atomic age and went well beyond exposure to radioactive isotopes. Experimental vaccines for hepatitis, measles, polio and other diseases, exploratory therapeutic procedures such as electroshock and lobotomy, and untested pharmaceuticals such as curare and thorazine were all tested on young children in hospitals, orphanages, and mental asylums as if they were some widely accepted intermediary step between chimpanzees and humans. Occasionally, children supplanted the chimps. Bereft of legal status or protectors, institutionalized children were often the test subjects of choice for medical researchers hoping to discover a new vaccine, prove a new theory, or publish an article in a respected medical journal. Many took advantage of the opportunity. One would be hard-pressed to identify a researcher whose professional career was cut short because he incorporated week-old infants, ward-bound juvenile epileptics, or the profoundly retarded in his experiments. In short, involuntary, non-therapeutic, and dangerous experiments on children were far from an unusual or dishonorable endeavor during the last century."--Provided by publisher.
  • Digital
    Alessandro Plebani, Vassilios Lougaris, editors.
    Springer2015
    This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discussing the highly orchestrated early B cell development in the bone marrow and the genes involved based on both human and animal models. The pathogenesis and clinical presentation of X-linked agammaglobulinemia, caused by mutations in the BTK (Bruton's tyrosine kinase) gene, are then presented in detail, followed by descriptions of the clinical manifestations and molecular basis of the less frequent autosomal recessive and autosomal dominant forms of agammaglobulinemia. Patients' management in terms of respiratory complications, gammaglobulin replacement therapy and the potential value of novel experimental therapeutic strategies are discussed. The book's closing chapters offer a comprehensive and updated description of mutations in the BTK gene, and the expression and function of BTK in cells other than B cells.
  • Digital/Print
    edited by Carlo A.P. Cavallotti, Luciano Cerulli.
    Digital : Springer2008
    Print2008
    Aging as risk factor in eye disease -- Age-related changes of the eyelid -- Aging effects on the optics of the eye -- Aging of the cornea -- The aging of the human lens -- The extracellular matrix of the aged human trabecular meshwork: changes of glucosaminoglycans -- Glial and mobile cells in the iris of the aging human eye -- Age-related diseases of the vitreous -- Age-related changes and/or diseases in the human retina -- Aging of the retinal pigmented epithelium -- The aging of the choroid -- Age-related macular degeneration I: types and future directions -- Age-related macular degeneration II: idiopathic macular holes -- Age-related macular degeneration III: epiretinal membranes -- Macular degeneration: ultrastructural age-related changes -- Non-exudative macular degeneration and management -- Treatment of intraocular pressure in elderly patients -- Aging of the lachrymal [lacrimal] gland -- The world according to blink: blinking and aging -- Age-related changes in the oculomotor system -- Rehabilitation of low vision in aged people -- Many suggestions to protect the eyes in aging people.
  • Digital
    edited by Frank G. Holz, Daniel Pauleikhoff, Richard F. Spaide, Alan C. Bird.
    Springer2013
    pt. 1. Pathophysiology. Epidemiology of AMD / L. Ho, R. van Leeuwen, P. T. V. M. de Jong, J. R. Vingerling and C. C. W. Klaver -- Genetics / L. G. Fritsche, U. Friedrich and B. H. F. Wxeber -- Ageing of the Retina and Retinal Pigment Epithelium / M. E. Boulton -- The Complement System in AMD / P. Charbel Issa, N. V. Chong and H. P. N. Scholl -- Histopathology / A. Lommatzsch, S. Wasmuth, D. Pauleikhoff, F. G. Holz and A. C. Bird -- pt. 2. Clinical Manifestations. Early AMD / M. Dietzel, D. Pauleikhoff, F. G. Holz and A. C. Bird -- Clinical Manifestations of Choroidal Neovascularization in AMD / R. F. Spaide -- Geographic Atrophy / M. Fleckenstein, S. Schmitz-Valckenberg, J. S. Sunness and F. G. Holz -- pt. 3. Diagnostics. Fundus Imaging of AMD / R. F. Spaide -- Optical Coherence Tomography / S. Wolf -- Microperimetry / E. Midena and E. Pilotto -- pt. 4. Prophylaxis and Therapy. Nutritional Supplementation in AMD / A. D. Meleth, V. R. Raiji, N. Krishnadev and E. Y. Chew -- Laser Photocoagulation and Photodynamic Therapy / G. Soubrane -- Anti-VEGF Therapy: Basics and Substances / S. Grisanti, J. Lüke and S. Peters -- Anti-VEGF Therapy for AMD: Results and Guidelines / P. Mitchell and S. Foran -- Combination Therapies for the Treatment of AMD / M. Barakat, N. Steinle and P. K. Kaiser -- Treatment Approaches for Dry AMD / Z. Yehoshua and P. J. Rosenfeld -- Surgical Therapy / B. Kirchhof -- pt. 5. Rehabilitation. Reading with AMD / S. Trauzettel-Klosinski -- Low Vision Aids in AMD / K. Rohrschneider.
  • Digital
    Allen C. Ho, Carl D. Regillo, editors.
    Springer2011
    1. Genetics of Age-Related Macular Degeneration / Daniel T. Kasuga, Yuhong Chen, and Kang Zhang -- 2. Modifiable Risk Factors of Age-Related Macular Degeneration / Hanna R. Coleman -- 3. Diagnosis of Age-Related Macular Degeneration / Jonathan Jonisch and Gaurav Shah -- 4. Fundus Imaging of Age-Related Macular Degeneration / Allen Chiang, Andre J. Witkin, Carl D. Regillo, and Allen C. Ho -- 5. Therapy of Nonexudative Age-Related Macular Degeneration / Annal D. Meleth, Veena R. Raiji, Nupura Krishnadev, and Emily Y. Chew -- 6. Management of Neovascular AMD / Fernando M. Penha and Philip J. Rosenfeld -- 7. Combination Therapy with Ocular Photodynamic Therapy for Age-Related Macular Degeneration / Nathan Steinle and Peter K. Kaiser -- 8. The Future of Non-neovascular Age-Related Macular Degeneration / Ketan Laud, Sri Krishna Mukkamala, Claudia Brue, and Jason S. Slakter -- 9. The Future of Neovascular Age-Related Macular Degeneration / Chirag P. Shah and Jeffrey S. Heier -- 10. The Economics of Age-Related Macular Degeneration / Gary C. Brown, Melissa M. Brown, Heidi B. Lieske, Philip A. Lieske, and Kathryn Brown.
  • Digital
    Paul Higgs, Chris Gilleard.
    Wiley2017
    "Groundbreaking exploration of the sociology of dementia -- with contributions from distinguished international scholars and practitioners. Organised around the four themes of personhood, care, social representations and social differentiation, Ageing, Dementia and the Social Mind provides a critical look at how modern concepts and assumptions regarding dementia can benefit from sociology and other disciplines. This collection addresses the gaps in our sociological knowledge of dementia and provides a forum for the development of new themes and perspectives within the health social sciences. This important work breaks new ground in giving specific attention to the social and cultural dimensions of responses to dementia"-- Provided by publisher.
  • Digital
    written by Siôn Eryl Jones; edited by Kathryn O'Neill.
    Research shows that for older people, cities present physical, social and economic barriers that prevent them realising their right to live in dignity and safety, or enjoying their surroundings. Groundbreaking initiatives to make cities more appropriate for older persons, such as the World Health Organization's Age-friendly Cities and Communities model, have led to improvements in a number of cities. Physical accessibility is absolutely essential, but thinking beyond this, what makes shared urban spaces and streets truly inclusive and liveable? What is the relationship between our health in older age and the physical, social and economic urban environment? What makes older people living in cities feel vulnerable to crime or disaster, and how does this affect their daily lives or the assistance they receive in times of crisis? These are some of the questions explored by this report. Focusing on low- and middle-income countries, this report aims to stimulate discussion about some of the actions that governments and city authorities can take to build truly inclusive cities.
  • Digital
    Valquiria Bueno, Janet M. Lord, Thomas A. Jackson, editors.
    Springer2017
    The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health. .
  • Print
    Alex Zhavoronkov.
    Status: Not Checked Out
    "Over the past twenty years, the biomedical research community has been delivering hundreds of breakthroughs expected to extend human lifespan beyond thresholds imaginable today. However, much of this research has not yet been adopted into clinical practice, nor has it been widely publicized. Just as the Internet and mobile communications were interwoven into our everyday lives over the past two decades, biomedicine will transform our society forever by allowing people to live longer and to continue working and contributing financially to the economy longer, rather than entering into retirement and draining the economy through pensions and senior healthcare. With a refocusing of medical national resources to regenerative medicine, old age will become a concept of the past, breakthroughs in regenerative medicine will continue, and an unprecedented boom to the global economy, with an influx of older able-bodied workers and consumers, will be a reality. A leading expert in aging research, author Alex Zhavoronkov provides a helicopter view on the progress science has already made, from repairing tissue damage to growing functional organs from a single cell, and illuminates the possibilities that the scientific and medical community will soon make into realities. The Ageless Generation is an engaging work that causes us to rethink our ideas of age and ability in the modern world"--Provided by publisher.
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    edited by Roberta Annicchiarico, Ulises Cortés, Cristina Urdiales, editors.
    Springer2008
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    Georg Lenz, Gilles Salles, editors.
    Springer2019
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    volume editors, Ladislas Robert, Tamas Fülöp.
    Karger2014
    The Commitment of human cells to senescence / R. Holliday -- Evolutionary theories of aging can explain why we age / E. Le Bourg -- Control of cell replication during aging / A. Macieira-Coelho -- Cell senescence : role in aging and age-related diseases / J. Campisi, L. Robert, -- Aging of cell membranes : facts and theories / I. Zs.-Nagy -- Oxidative stress, mitochondrial dysfunction, and the mitochondria theory of aging / Y. Kong, S.E. Trabucco, H. Zhang -- Aging of connective tissues : experimental facts and theoretical considerations / J. Labat-Robert, L. Robert -- Aging of cell communication : loss of receptor function / L. Robert, T. Fulop -- On the immunological theory of aging / T. Fulop, J.M. Witkowski, G. Pawelec, C. Alan, A. Larbi -- Aging of the brain, dementias, role of infectious proteins : facts and theories / F. Morinet -- Aging as alteration / P.-A. Miquel -- Longevity and its regulation : centenarians and beyond / L. Robert, T. Fulop.
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    Danon, D.; Marois, M.; Shock, Nathan W.
    Status: Not Checked Out
    v. 1. Biology / edited by D. Danon, N.W. Shock, and M. Marois -- v. 2. Medicine / edited by A.J.J. Gilmore, A. Svanborg, M. Marois. Social sciences and social policy / edited by Walter M. Beattie, Jr., Jerzy Piotrowski, M. Marois -- v. 3. Behavioural sciences / edited by James E. Birren ... [et al.]. Conclusions and perspectives / edited by Maurice Marois.
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    edited by Richard Pak, Anne Collins McLaughlin.
    ScienceDirect2018
    Aging, Health and Technology takes a problem-centered approach to examine how older adults use technology for health. It examines the many ways in which technology is being used by older adults, focusing on challenges, solutions and perspectives of the older user. Using aging-health technology as a lens, the book examines issues of technology adoption, basic human factors, cognitive aging, mental health, aging and usability, privacy, trust and automation. Each chapter takes a case study approach to summarize lessons learned from unique examples that can be applied to similar projects, while also providing general information about older adults and technology.
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    Stephen Bondy, Kenneth Maiese, editors.
    Springer2010
    Part 1. General Aspects of Aging -- Protein Redox-Regulation Mechanisms in Aging / Ufuk Çakatay -- Nitrosative Stress in Aging - Its Importance and Biological Implications in NF-κB Signaling / Predrag Ljubuncic, Einat Gochman and Abraham Z. Reznick -- Intervention with Multiple Micronutrients Including Dietary and Endogenous Antioxidants for Healthy Aging / Kedar N. Prasad -- Advanced Glycation End Products, RAGE, and Aging / Ravichandran Ramasamy, Loredana G. Bucciarelli, Shi Fang Yan and Ann Marie Schmidt -- Sirtuins and Mammalian Aging / Edward H. Sharman -- Estrogenic Modulation of Longevity by Induction of Antioxidant Enzymes / Jose Viña, Consuelo Borrás, Mari Carmen Gómez-Cabrera, Juan Gambini and Raul López-Grueso, et al. -- Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction / Shi-Bei Wu, Yu-Ting Wu, Chih-Hao Wang, Wan-Yu Lee and Yau-Huei Wei -- Methylglyoxal, Oxidative Stress, and Aging / Miklós Péter Kalapos, Kaushik M. Desai and Lingyun Wu -- Part 2. The Cardiovascular System -- Novel Strategies for Neurovascular Longevity During Aging / Kenneth Maiese, Zhao Zhong Chong, Jinling Hou and Yan Chen Shang -- Oxidative Stress in Vascular Disease / Isabelle Gorenne and Martin R. Bennett -- The Role of Mitochondrial Reactive Oxygen Species Formation for Age-Induced Vascular Dysfunction / Andreas Daiber, Joachim Kienhoefer, Rebecca Zee, Philip Wenzel and Volker Ullrich, et al. -- Aging, Oxidative Stress, and Cardiovascular Disorders / Yi Shi, Giovanni G. Camici and Thomas F. Lüscher -- Oxidative Stress, Aging, and Cardiovascular Disease / G. Riccioni, V. Sblendorio and N. D'Orazio -- Antioxidation in Prevention of Cardiovascular Diseases - An Effect of Polyphenols / Jun-ichi Suzuki, Mitsuaki Isobe, Ryuichi Morishita and Ryozo Nagai -- Vascular Aging and Oxidative Stress: Hormesis and Adaptive Cellular Pathways / Nathalie Thorin-Trescases and Eric Thorin -- Role of Oxidative Stress in Mediating Elevated Blood Pressure with Aging / Julio Sartori Valinotti, Licy Yanes and Jane F. Reckelhoff -- Part 3. The Nervous System -- Melatonin, Oxidative Stress, and the Aging Brain / Stephen Bondy and Edward H. Sharman -- The SAM Strain of Mice, a Higher Oxidative Stress, Age-Dependent Degenerative Disease, and Senescence Acceleration Model / Yoichi Chiba, Atsuyoshi Shimada and Masanori Hosokawa -- Antioxidants Combined with Behavioral Enrichment Can Slow Brain Aging / Elizabeth Head -- Role of Nitric Oxide in Neurodegeneration and Vulnerability of Neuronal Cells to Nitric Oxide Metabolites and Reactive Oxygen Species / Debomoy K. Lahiri, Chandramallika Ghosh, Jack T. Rogers, Stephen Bondy and Nigel H. Greig -- Free Radical-Mediated Damage to Brain in Alzheimer's Disease: Role of Acrolein and Preclinical Promise of Antioxidant Polyphenols / Charles Ramassamy, Madeleine Arseneault and Dang Thanh Nam -- An Epigenetic Model for Susceptibility to Oxidative DNA Damage in the Aging Brain and Alzheimer's Disease / Nasser H. Zawia and Fernando Cardozo-Pelaez.
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    Zhao Wang, editor.
    Springer2018
    "This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field"--Publisher's description.
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    volume editors, Anatoliy I. Yashin, Durham, NC, Michal Jazwinsk, New Orleans, La.
    Karger2015
    Introduction to the theory of aging networks / Witten, T.M. -- Applications to aging networks / Wimble, C., Witten, T.M. -- Computational systems biology for aging research / Auley, M.T., Mooney, K.M. -- How does the body know how old it is? Introducing the epigenetic clock hypothesis / Mitteldorf, J. -- The great evolutionary divide : two genomic systems biologies of aging / Rose, M.R., Cabral, I.G., Philips, M.A., Rutledge, G.A., Phung, K.H., Mueller, L.D., Greer, L.F. -- Development and aging : two opposite but complementary phenomena / Feltes, B.C., De Faria Poloni, J., Bonatto, D. -- Aging as a process of deficit accumulation : its utility and origin / Mitnitski, A., Rockwood, K. -- Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease / Guarner, V., Rubio-Ruiz, M.E. -- Modulating mTOR in aging and health / Johnson, S.C., Sangesland, M., Kaeberlein, M., Rabinovitch, P. -- Melatonin and circadian oscillators in aging : a dynamic approach to the multiply connected players / Hardeland, R. -- Diet-microbiota-health interactions in older subjects : implications for healthy aging / Lynch, D.B., Jeffery, I.B., Cusack, S., O'Connor, E.M., O'Toole, P.W. -- Systems biology approaches in aging research / Chauhan, A., Liebal, U.W., Vera, J., Baltrusch, S., Junghanss, C., Tiedge, M., Fuellen, G., Wolkenhauer, O., Köhling, R. -- Conservative growth hormone/IGF-1 and mTOR signaling pathways as a target for aging and cancer prevention : do we really have an antiaging drug? / Anisimov, V.N.
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    Bodh I. Jugdutt, editor.
    Springer2014
    This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis; and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and internists.
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    Margaret Pisani, editor.
    Springer2012
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    Daniel L. Segal, Sara Honn Qualls, and Michael A. Smyer.
    Wiley2018
    Introduction. Mental Health and Aging -- Basic Gerontology for Working with Older Adults -- Psychological Bases of Positive Mental Health -- Models of Mental Health in Later Life. Models of Mental Health in Later Life -- Psychodynamic Model / Lacey Edwards -- Cognitive-Behavioral Model -- Stress and Coping Model -- Family Systems Model -- Summary and Commentary -- Introduction to Mental Disorders. Introduction to Mental Disorders -- Cognitive Impairment and Neurocognitive Disorders -- Major Depression and Bipolar Disorder -- Serious Mental Disorders in Older Adults / Stephen J Bartels, Karen L Fortuna, John A Naslund -- Anxiety Disorders, Hoarding Disorder, and Post-Traumatic Stress Disorder -- Sexual Disorders, Sleep Disorders, and Chronic Pain -- Substance-Related Disorders and Personality Disorders -- Settings and Contexts of Mental Health. Settings and Contexts of Mental Health -- Health Services Delivery Systems -- Housing, Social Services, and Mental Health -- Family and Friend Relationships, and Caregiving -- Ethical Issues in Work with Older Adults.
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    Ronan M. Factora, editor.
    Springer2014
    Increasingly, we hear of more and more elders falling victim to financial exploitation. Although this form of elder abuse has been recognized for years, its incidence, prevalence, and impact on the common individual has been only more recently brought to the spotlight. Despite these circumstances, recognition of risk factors and indicators of financial exploitation are not widely disseminated. Additionally, once situations are identified and confronted, the knowledge of what to do next is lacking. These gaps are present within the medical community, law-enforcement, and the finance community ? areas where opportunities for recognition and intervention are common. Our elders often have no idea of what to do when they see their own risk or when they fall victim. Aging and Money: Reducing Risk of Financial Exploitation and Protecting Financial Resources helps clinicians to integrate identification of such indicators of abuse into their geriatric assessment as well as guide them in performing an assessment of an individuals? financial decision-making capacity when appropriate. Aging and Money: Reducing Risk of Financial Exploitation and Protecting Financial Resources is an essential new text that provides the practicing clinician with information on identifying risk factors and clinical clues associated with financial exploitation and how to incorporate these steps into their practice.
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    José Marín-García ; with the collaboration of Michael J. Goldenthal, Gordon W. Moe.
    Springer2008
    Post-genomic view of aging: definition, theories and observations -- Overview of cardiovascular aging -- Molecular and cellular methodologies: a primer -- Molecular and cellular phenotypes of cardiovascular aging -- Aging of the vasculature and related systems -- Aging and the cardiovascular-related systems -- Cardiomyopathy and heart failure in aging -- Atherosclerosis, hypertension and aging -- Metabolic syndrome, diabetes and cardiometabolic risks in aging -- Gender and cardiovascular diseases in aging -- Cardiac dysrhythmias and channelopathies in aging -- Genetics of life span: lessons from model organisms -- Profiling the aging cardiovascular system: transcriptional, proteomic, SNPs, gene mapping and epigenetics analysis -- Translational research: gene, pharmacogenomics and cell-based therapy in the aging heart -- Nutrition and exercise in cardiovascular aging: metabolic and pharmacological interventions -- Aging and the frontier ahead.
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    edited by Karen Eggleston and Shripad Tuljapurkar.
    Status: Not Checked Out
    Preface / Michael Armacost -- Introduction / Karen Eggleston and Shripad Tuljapurkar -- Population aging and economic growth / David E. Bloom -- How demography shapes individual, social, and economic transitions in Asia / Shripad Tuljapurkar -- Changing intergenerational transfers in aging Japan / Naohiro Ogawa, Amonthep Chawla and Rikiya Matsukura -- Gender, migration, and the well-being of the elderly in rural China / Shuzhuo Li ... [et al.] -- Marriage and the elderly in China / Maria Porter -- Financing health care in a rapidly aging Japan / Naoki Ikegami -- Population aging and the introduction of long-term care insurance in South Korea / Soonman Kwon -- Old-age pension reform in South Korea / Byongho Tchoe -- The diabetes epidemic in the Asia-Pacific / Karen Eggleston ... [et al.] -- Families dealing with dementia : insights from mainland China, Hong Kong, and Taiwan / Dolores Gallagher-Thompson ... [et al.] -- Elderly care in Singapore : the state as last resort / Meng-kin Lim.
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    [edited by] Sandra Gordon-Salant, Robert D. Frisina, Arthur N. Popper, Richard R. Fay
    Springer2010
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    Martha Hostetter, Sarah Klein, and Douglas McCarthy.
    We examine the Program of All-Inclusive Care for the Elderly (PACE) model of care, focusing on On Lok Senior Health Services as the original program and exploring the potential for the model to be adapted and spread.
  • Digital
    Ralph M. Trüeb, Desmond J. Tobin, editors.
    Springer2010
    Gerontobiology of the Hair Follicle / Desmond J. Tobin -- Molecular Basis of Androgenetic Alopecia / Valerie Anne Randall -- Inflammatory Phenomena and Fibrosis in Androgenetic Alopecia / Ralph M. Trüeb -- Post-Menopausal Frontal Fibrosing Alopecia / Steven Kossard -- Female Pattern Hair Loss / M. Javed Mohungoo and Andrew G. Messenger -- Hair Growth Parameters in Pre- and Postmenopausal Women / Paradi Mirmirani, Fangyi Luo, Scott R. Youngquist, Brian K. Fisher and James Li, et al. -- Comparative Histopathology of Androgenetic Alopecia, Diffuse Alopecia, and Senescent Alopecia / David A. Whiting -- Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis / Paradi Mirmirani and Pratima Karnik -- The Aging Hair Pigmentary Unit / Desmond J. Tobin -- Oxidative Stress Associated Melanocyte-Loss and Hair Growth Capacity in the Aging Hair Follicle: A Model for Tissue-Specific Aging / Eva M. J. Peters -- Human Hair Follicle Melanocytes as a Proxy Cell Type in Neurodegeneration Research / Nikolaos Papageorgiou, Elisabeth Carpenter and Desmond J. Tobin -- Effect of UV Radiation on Scalp and Hair Growth / Claudine Piérard-Franchimont, Pascale Quatresooz and Gérald E. Piérard -- Hair Photoaging / Won-Soo Lee -- Effect of Tobacco Smoking on Hair / Ralph M. Trüeb -- Age-Related General Problems Affecting the Condition of Hair / Ralph M. Trüeb -- Aging of Scalp and Age-Related Disorders of Scalp / Desmond Gan and Rodney Sinclair -- Care of Aging Hair and Photoprotection / Zoe Diana Draelos -- Possibilities and Limitations for Reversal of Age-Related Hair Loss / Nina Otberg, Isabel Restrepo and Jerry Shapiro -- Possibilities and Limitations for Reversal of Age-Related Pigment Loss / Ralph M. Trüeb -- Evidence-Based Hair Transplantation / Andreas M. Finner -- Future Directions: Gene Polymorphism Diagnostics Relevant to Hair / Justine A. Ellis -- Future Directions : The Known and Unknown Roles of Hair-Follicle Stem Cell Types / Robert M. Hoffman -- Future Directions: Bioengineering the Hair Follicle / Kurt S. Stenn, Ying Zheng and Jen-Chih Hsieh -- Hair After Death / Andrew S. Wilson and Desmond J. Tobin.
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    prepared by Jacob Siegel.
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    edited by Juan F. Macías Núñez, J. Stewart Cameron, Dimitrios G. Oreopoulos.
    Springer2008
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    edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun.
    Springer2012
    Introduction -- Oxidative stresses and ageing -- The role of mitochondria in the aging processes of yeast -- The retrograde response and other pathways of interorganelle communication in yeast replicative aging -- Chronological aging in Saccharomyces cerevisiae -- Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- Maximising the yeast chronological lifespan -- Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae -- DNA damage and DNA replication stress in yeast models of aging -- Yeast aging and apoptosis -- Cellular homeostasis in fungi: impact on the aging process -- Genome-wide analysis of yeast aging -- Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities -- Evolution of asymmetric damage segregaton: a modelling approach -- Cellular ageing and the actin cyoskeleton.
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    Kiyoshi Makiyama, Shigeru Hirano, editors.
    Springer2017
    "This book discusses the aging voice, one of the interesting issues related to aging. Population aging is an issue in most developed countries, where both physicians and specialists are required to improve clinical and scientific practice for elderly adults. In particular, the need for expertise in the diagnosis and treatment of aging voice pathologies is increasing continually. New developments in regenerative medicine have taken care for the aging voice to new level, and the contributors to this book use their wealth of experience in the field of the aging voice to present the latest advances in this field. This book is a unique resource, providing new perspectives for physicians, clinicians and health care workers who are interested in the aging voice."--Back cover.
  • Digital
    Jean Galiana, William A. Haseltine.
    Springer2019
    This open access book outlines the challenges of supporting the health and wellbeing of older adults around the world and offers examples of solutions designed by stakeholders, healthcare providers, and public, private and nonprofit organizations in the United States. The solutions presented address challenges including: providing person-centered long-term care, making palliative care accessible in all healthcare settings and the home, enabling aging-in-place, financing long-term care, improving care coordination and access to care, delivering hospital-level and emergency care in the home and retirement community settings, merging health and social care, supporting people living with dementia and their caregivers, creating communities and employment opportunities that are accessible and welcoming to those of all ages and abilities, and combating the stigma of aging. The innovative programs of support and care in Aging Well serve as models of excellence that, when put into action, move health spending toward a sustainable path and greatly contribute to the well-being of older adults.
  • Digital
    James Masten, with James Schmidtberger.
    eBook Comp Acad2011
    Section I. Aging means changing. Introduction -- "I'm still here." -- Physical changes : AIDS or age? -- Who do you consider a friend nowadays? -- Being gay at midlife -- Let's talk about sex -- Love and marriage -- In the family -- What about work? -- My, how you've grown -- Summary -- Section II. Adaptation versus stagnation. Introduction -- Learning from the past or living in the past? -- Living within limitations or letting your world shrink? -- Accepting yourself or stuck in your ways? -- One day at a time or avoiding the future? -- Summary -- Section III. Ten steps to optimal aging with HIV. Introduction -- Care for your physical health -- Rebuild and maintain your social networks -- Be generative -- Fight the triple threat : AIDS stigma, homophobia, and ageism -- Let yourself grieve -- Check your baggage -- Develop effective coping strategies -- Renew your spirituality -- Plan for the future -- Play -- Conclusion -- About the study -- Using this book in a group.
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    by Wan He, Daniel Goodkind, and Paul Kowal.
    This report covers the demographic, health, and economic aspects of global population aging. After an examination of past and projected growth of the older population and dynamics of population aging, the report then covers health, mortality, and health care of the older population. Finally, work, pensions, and other economic characteristics of older people are addressed. Compared to previous versions of the report An Aging World, this edition is unique for expanding the analysis of aging trends to all countries and areas, with an emphasis on the differences among world regions. Where data are available, it also updates the latest statistics and trends for health and economic indicators.
  • Print
    edited by Stanton B. Gelvin.
  • Digital
    edited by Kan Wang, Center for Plant Transformation, Plant Sciences Institute, and Department of Agronomy, Iowa State University, Ames, IA, USA.
    Volume 1. Gateway®-compatible plant transformation vectors /Mark A. Smedley and Wendy A. Harwood -- Brachypodium distachyon /Jennifer N. Bragg ... [et al.] -- Medicago truncatula transformation using cotyledonary explants /Elane Wright and Zeng-Yu Wang -- Medicago truncatula transformation using leaf explants /Viviane Cosson, Alexis Eschstruth , and Pascal Ratet -- Setaria viridis /Joyce Van Eck and Kerry Swartwood -- Barley (Hordeum vulgare L.) transformation using immature embryos /Cornelia Marthe, Jochen Kumlehn, and Goetz Hensel -- Barley (Hordeum vulgare L.) transformation using embryogenic pollen cultures /Ingrid Otto, Andrea Müller, and Jochen Kumlehn -- Maize (Zea mays L.) /Bronwyn Frame ... [et al.] -- Maize, tropical (Zea mays L.) /Shireen K. Assem -- Finger millet [Eleusine coracana (L.) Gaertn.] /Stanislaus Antony Ceasar and Savarimuthu Ignacimuthu -- Oat (Avena sativa L.) /Sebastian Gasparis and Anna Nadolska-Orczyk -- Rice, indica (Oryza sativa L.) /Yukoh Hiei, Yuji Ishida, and Toshihiko Komari -- Rice, japonica (Oryza sativa L.) /Marcy Main, Bronwyn Frame, and Kan Wang -- Sorghum (sorghum bicolor ) /Xiaomei Guo, Zhengxiang Ge, Shirley J. Sato, and Tom E. Clemente -- Wheat (Triticum aestivum L.) transformation using immature embryos /Yuji Ishida ... [et al.] -- Wheat (Triticum aestivum L.) transformation using mature embryos /Eva Medvecká and Wendy A. Harwood -- Alfalfa (Medicago sativa L.) /Chunxiang Fu ... [et al.] -- Clovers (Trifolium spp.) /Samira Rahimi-Ashtiani ... [et al.] -- Clover, red (Trifolium pratense) /Michael L. Sullivan and Kenneth H. Quesenberry -- Cowpea [Vigna unguiculata (L.) walp.] /Ratikanta Behura ... [et al.] -- Lentil (Lens culinaris medik) /Ufuk Celikkol Akcay, Meral Yücel, and Hüseyin Avni Öktem -- Soybean [Glycine max (L.) Merr.] /Diane Luth, Katey Warnberg, and Kan Wang -- Brassica oleracea and B. napus /Penny A. C. Hundleby née Sparrow and Judith A. Irwin -- Cucumber (Cucumis sativus L.) and kabocha squash (Cucurbita moschata Duch) /Yoshihiko Nanasato and Yutaka Tabei -- Pepper, chili (Capsicum annuum) /Jung Min ... [et al.] -- Pepper, sweet (Capsicum annuum) /Iris Heidmann and Kim Boutilier -- Sugar beet (Beta vulgaris L.) /Hiroyo Kagami ... [et al.] -- Tomato (Solanum lycopersicum) /Dora Garcia, Javier Narváez-Vásquez, and Martha L. Orozco-Cárdenas.
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    edited by Marilyn S. Arsham, Margaret J. Barch, Helen J. Lawce.
    Wiley2017
    The cell and cell division / Margaret J Barch, Helen J Lawce -- Cytogenetics: an overview / Helen J Lawce, Michael G Brown -- Peripheral blood cytogenetic methods / Helen J Lawce, Michael G Brown -- General cell culture principles and fibroblast culture / Debra F Saxe, Kristin M May, Jean H Priest -- Prenatal chromosome diagnosis / Kristin M May, Debra F Saxe, Jean H Priest -- Chromosome stains / Helen J Lawce -- Human chromosomes: identification and variations / Helen J Lawce, Luke Boyd -- ISCN: the universal language of cytogenetics / Marilyn S Arsham, Lisa G Shaffer -- Constitutional chromosome abnormalities / Kathleen Kaiser-Rogers -- Genomic imprinting / R Ellen Magenis -- Cytogenetic analysis of hematologic malignant diseases / Nyla A Heerema -- Cytogenetic methods and findings in human solid tumors / Marilu Nelson -- Chromosome instability syndromes / Yassmine Akkari -- Microscopy and imaging / Margaret J Barch, Helen J Lawce -- Computer imaging / Christine E Haessig -- Fluorescence in situ hybridization (FISH) / Helen J Lawce, Jeffrey S Sanford -- Multicolor FISH (SKY and M-FISH) and CGH / Turid Knutsen -- Genomic microarray technologies for the cytogenetics laboratory / Bhavana J Davé, Warren G Sanger -- Mathematics for the cytogenetic technologist / Patricia K Dowling -- Selected topics on safety, equipment maintenance, and compliance for the cytogenetics laboratory / Helen Jenks, Janet Krueger -- A system approach to quality / Peggy J Stupca, Sheryl A Tran -- Laboratory management / Mervat S Ayad, Adam Sbeiti -- Laboratory information system / Peining Li, Richard Van Rheeden -- Animal cytogenetics / Marlys L Houck, Teri L Lear, Suellen J Charter -- Online genetic resources and references / Wahab A Khan.
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    Aurigemma, Gerard P.; Nixon, J. V.
    Ovid2011
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    [edited by] Laurent Zelek, Nicole Zernik.
    Springer2010
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    Robert Lorway.
    Springer2017
    Introduction -- Section I. Canada: Professionalization: Chapter 1: A Vital Response -- Chapter 2: Treatment Rebellions -- Section II. India: Techno-Bureaucracies: Chapter 3: Geographies of Intervention -- Chapter 4: Documenting Sovereignty -- Section III. Kenya: Bioexperimentalization -- Chapter 5: A South-to-South Collaboration -- Chapter 6:The Logic of Verification -- Conclusion.
  • Print
    Victoria A. Harden.
    Status: Not Checked Out
    Society was not prepared in 1981 for the appearance of a new infectious disease, but we have since learned that emerging and reemerging diseases will continue to challenge humanity. This work is the first history of HIV/AIDS written for a general audience that emphasizes the medical response to the epidemic. The author, a medical historian approaches the AIDS virus from philosophical and intellectual perspectives in the history of medical science, discussing the process of scientific discovery, scientific evidence, and how laboratories found the cause of AIDS and developed therapeutic interventions. Furthermore, her book places AIDS as the first infectious disease to be recognized simultaneously worldwide as a single phenomenon. After years of believing that vaccines and antibiotics would keep deadly epidemics away, researchers, doctors, patients, and the public were forced to abandon the arrogant assumption that they had conquered infectious diseases. By presenting a discussion of the history of HIV/AIDS and analyzing how aspects of society advanced or hindered the response to the disease, the book illustrates how medicine identifies and evaluates new infectious diseases quickly and what political and cultural factors limit the medical community's response.
  • Digital