Books

U

  • Digital
    Committee on the U.S. Commitment to Global Health, Board on Global Health, Institute of Medicine of the National Academies.
    Digital : NAP2009
    Summary -- Charge to the committee -- a prominent role for health in U.S. foreign policy -- Progress in global health can be achieved now -- Urgent opportunity for action -- Restructure the U.S. global health enterprise -- Mobilize financial resources for health -- Focus U.S. government efforts on health outcomes -- Advance U.S. strengths in global health knowledge -- Support and collaborate with the WHO -- Call to action.
  • Digital
    Committee on the U.S. Commitment to Global Health, Board on Global Health, Institute of Medicine of the National Academies.
    Digital : NAP2009
    The U.S. Commitment to Global Health examines ways in which the United States could contribute to advances in global health, including the following four areas of action: Generate and share knowledge to address problems endemic to poor countries, Invest in people, institutions, and capacity building in resource-poor settings, Increase both quantity and quality of U.S. financial commitments to global health, Be a respectful partner and leader.
  • Digital
    Digital : CDC1989-Scroll down to U.S. Decennial Life Tables for 1989 to 1991.
    no. 1. Alabama -- no. 2. Alaska -- no. 3. Arizona -- no. 4. Arkansas -- no. 5. California -- no. 6. Colorado -- no. 7. Connecticut -- no. 8. Delaware -- no. 9. District of Columbia -- no. 10. Florida -- no. 11. Georgia -- no. 12. Hawaii -- no. 13. Idaho -- no. 14. Illinois -- no. 15. Indiana -- no. 16. Iowa -- no. 17. Kansas -- no. 18. Kentucky -- no. 19. Louisiana -- no. 20. Maine -- no. 21. Maryland -- no. 22. Massachusetts -- no. 23. Michigan -- no. 24. Minnesota -- no. 25. Mississippi -- no. 26. Missouri -- no. 27. Montana -- no. 28. Nebraska -- no. 29. Nevada -- no. 30. New Hampshire -- no. 31. New Jersey -- no. 32. New Mexico -- no. 33. New York -- no. 34. North Carolina -- no. 35. North Dakota -- no. 36. Ohio -- no. 37. Oklahoma -- no. 38. Oregon -- no. 39. Pennsylvania -- no. 40. Rhode Island -- no. 41. South Carolina -- no. 42. South Dakota -- no. 43. Tennessee -- no. 44. Texas -- no. 46. Vermont -- no. 47. Virginia -- no. 48. Washington -- no. 49. West Virginia -- no. 50. Wisconsin-- no. 51. Wyoming.
  • Digital
    Panel on Understanding Cross-National Health Differences Among High-Income Countries ; Steven H. Woolf and Laudan Aron, editors ; Committee on Population, Division of Behavioral and Social Sciences and Education ; Board on Population Health and Public Health Practice, Institute of Medicine ; National Research Council and Institute of Medicine of the National Academies.
    Digital : NAP2013
    "The United States is among the wealthiest nations in the world, but it is far from the healthiest. Although life expectancy and survival rates in the United States have improved dramatically over the past century, Americans live shorter lives and experience more injuries and illnesses than people in other high-income countries. The U.S. health disadvantage cannot be attributed solely to the adverse health status of racial or ethnic minorities or poor people: even highly advantaged Americans are in worse health than their counterparts in other, "peer" countries. In light of the new and growing evidence about the U.S. health disadvantage, the National Institutes of Health asked the National Research Council (NRC) and the Institute of Medicine (IOM) to convene a panel of experts to study the issue. The Panel on Understanding Cross-National Health Differences Among High-Income Countries examined whether the U.S. health disadvantage exists across the life span, considered potential explanations, and assessed the larger implications of the findings. U.S. Health in International Perspective presents detailed evidence on the issue, explores the possible explanations for the shorter and less healthy lives of Americans than those of people in comparable countries, and recommends actions by both government and nongovernment agencies and organizations to address the U.S. health disadvantage"--Publisher's description.
  • Digital
    [compiled by]: Jeffrey S Reznick and Kenneth Koyle; with the staff of the US National Library of Medicine.
    Digital : NLM2017
    "... A general introduction to the history of the library primarily through its own rich image collections and a handful of others selected from the collections of the National Archives, the National Museum of Health and Medicine, the Smithsonian Institution Archives, and the Rudolph Matas Library of the Health Sciences at Tulane University."--Introduction.
  • Digital
    edited by Raymond J. Deshaies.
    Digital : ScienceDirectpt. A
    Digital : ScienceDirectpt. B
  • Digital
    edited by R. Jürgen Dohmen, Martin Scheffner.
    Digital : Springer Protocols2012
  • Print
    Ivette Shiba Estay.
    Status: Not Checked OutLane Catalog Record
  • Digital
    volume editor, Stefan Jentsch, Bernhard Haendler.
    Digital : Springer2009
  • Digital
    edited by Robert Hubrecht and James Kirkwood.
    Digital : Wiley2010
  • Digital
    editor, Steven M. Kurtz.
    Digital : ScienceDirect2009
    Digital : Knovel2009
    A primer on UHMWPE / Steven M. Kurtz -- From ethylene gas to UHMWPE component : the process of producing orthopedic implants / Steven M. Kurtz -- Packaging and sterilization of UHMWPE / Steven M. Kurtz -- The origins of UHMWPE in total hip arthroplasty / Steven M. Kurtz -- The clinical performance of UHMWPE hip replacements / Steven M. Kurtz -- Contemporary total hip arthoplasty : hard-on-hard bearings and highly crosslinked UHMWPE / Steven M. Kurtz, Kevin Ong -- The origins and adaptations of UHMWPE for knee replacements / Steven M. Kurtz -- The clinical performance of UHMWPE in knee replacements / Steven M. Kurtz -- The clinical performance of UHMWPE in shoulder replacements / Stefan M. Gabriel -- The clinical performance of UHMWPE in elbow replacements / Judd S. Day -- Applications of UHMWPE in total ankle replacements / Allyson Ianuzzi, Chimba Mkandawire -- The clinical performance of UHMWPE in the spine / Steven M. Kurtz, Marta L. Villarraga, Allyson Ianuzzi -- Highly crosslinked and melted UHMWPE / Orhun K. Muratoglu -- Highly crosslinked and annealed UHMWPE / John H. Dumbleton, Aiguo Wang, Kate Sutton ...[et al.] -- Highly crosslinked UHMWPE doped with vitamin E / Ebru Oral, Orhun K. Muratoglu -- Vitamin-E-blended UHMWPE biomaterials / Steven M. Kurtz, Pierangiola Bracco, Luigi Costa -- Composite UHMWPE biomaterials and fibers / Steven M. Kurtz -- UHMWPE / hyluronan microcomposite biomaterials / Susan P. James, Rachel (Kurkowski) Oldinski, Min Zhang ...[et al.] -- High pressure crystallized UHMWPEs / Anuj Bellare, Steven M. Kurtz -- Compendium of highly crosslinked UHMWPEs / Steven M. Kurtz -- Mechanisms of crosslinking, oxidative degradation and stabilization of UHMWPE / Luigi Costa, Pierangiola Bracco -- In vivo of UHMWPE / Steven M. Kurtz -- Pathophysiologic reactions to UHMWPE wear particles / Marla J. Steinbeck, Ryan M. Baxter, Theresa A. Freeman -- Characterization of physical, chemical, and mechanical properties of UHMWPE / Stephen Spielgelberg -- Tribological assessment of UHMWPE in the hip / Aaron Essner MS, Aiguo Wang -- Tribological assessment of UHMWPE in the knee / Hani Haider -- Characterization of UHMWPE wear particles / Tipper JL., Richards L., Ingham E. ...[et al.] -- Clinical surveillance of UHMWPE using radiographic methods / Charles R. Bragdon -- ESR insights into macroradicals in UHMWPE / M. Shah Jahan -- Fatigue and fracture of UHMWPE / Francisco J. Medel, Jevan Furmanski -- Development and application of the notched tensile test to UHMWPE / Michael C. Sobieraj, Clare M. Rimnac -- Development and application of the small punch test to UHMWPE / Avram A. Edidin -- Nano- and microindentation testing of UHMWPE / Jeremy L. Gilbert, James D. Wernle -- MicroCT analysis of wear and damage in UHMWPE / Daniel MacDonald, Anton Bowden, Steven M. Kurtz -- Computer modeling and simulation of UHMWPE / Anton E. Bowden, Erin Oneida, Jorgen Bergström.
  • Digital
    Ullmann, Fritz.
    Digital : Wiley2005-
    Covers science and technology in all areas of industrial chemistry, containing nearly 1000 major articles with more than 16 million words, nearly 10,000 tables, 30,000 figures, and literature sources and cross-references. It also includes full text index, author index, CAS registry number index, and keyword index.
  • Digital
    Giuliano Gentili, Mario Di Napoli.
    Digital : Springer2016
  • Print
    [edited by] Brian Freeman.
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    [edited by] Brian S. Freeman.
    Digital : AccessMedicine2013
    Online 3rd edition inlcudes only selected chapters as of 1/10/2014.
  • Digital
    Pierre-Marie Robitaille, Lawrence Berliner [eds.].
    Digital : Springer2006
  • Digital
    Thomas Patrick Niedringhaus.
    Digital2012
    Since the 2003 completion of the human genome by means of the Sanger-based DNA sequencing strategy and capillary array electrophoresis, the scientific and medical community has worked to make personalized medicine a reality. Next-generation DNA sequencing technologies with astoundingly high throughput are now in use and have provided exciting new capabilities. However, next-generation instruments are currently incapable of providing highly accurate, long sequencing read lengths, have difficulty sequencing through repetitive sequences, and have yet to "scale down" well for point-of-care diagnostics. The 600 to 700 base read lengths at 98% accuracy that are provided by capillary electrophoresis and the Sanger method are still the gold standard for medical sequencing. In recent years, there has been a natural progression from CAE to microchip electrophoresis. Microchip electrophoresis provides highly accurate sequencing at a small compromise to read length (~ 500 to 600 bases) while offering the potential for a significant increase in throughput due to the reduced separation times and the possibility to create a lab-on-a-chip (LOC) device that integrates upstream sample preparation steps. These advantages render CAE and microchip electrophoresis platforms desirable for clinical diagnostic tests since they offer highly accurate sequencing needed to analyze medically relevant genes and precisely genotype forensic samples. Therefore, this work focuses on understanding variables that influence the migration mechanism of single-stranded DNA (ssDNA) through physically- entangled polymer matrices used in CAE and microchip electrophoresis in an effort to increase throughput and bridge the gap for clinical adoption. First, I discuss the application of the biased reptation model (BRM) to CAE sequencing separations. In this study, I report the synthesis and characterization of an ultra-high molar mass linear polyacrylamide (LPA) to be used as a replaceable, physically-entangled polymer matrix and the migration mechanisms of ssDNA through the LPA matrices are evaluated using reptation plots. Properties of the LPA matrices (i.e. average pore size and viscosity) is tuned by the overall polymer concentration as well as mixing ultra-high and low molar mass LPA. In the end, a blended LPA solution generates a dynamically responsive polymer matrix that increases sequencing read lengths by delaying the onset of oriented biased reptation. The near-optimal blended LPA matrix which extends average read lengths to 830 bases in ~1 hour on a high-throughput CAE instrument. This represents a performance that is substantially better than the best commercial instrument/matrix CAE system available, which takes 2 hours to produce 830 bases. This was achieved by matrix optimization only. Second, I discuss transient effects on the DNA sequencing read length caused by shear-induced LPA stretching during the pressure-induced capillary loading of the polymer matrix which results in entanglement inhomogeneity. The network inhomogeneity, in turn, increases peak widths due to mobility variation among ssDNA fragments in the radial direction of the microchannel. The contributions of the matrix rheological properties, microchannel dimensions, and loading pressure to the shear forces placed on the matrix during loading are thoroughly examined. Finally, tests were carried out on microfluidic chips to reduced polymer network disruption. In the end, the loading conditions were optimized to enable loading and unloading of a sequencing matrix in less than 1 minute that also provides sequencing read lengths on the order of 550 to 600 bases in ~ 8 minutes. These results provide universal parameters for high-throughput loading of polymer matrices into capillaries and microchips used in electrophoretic genotyping assays and newly invented LOC platforms, such that the performance of the matrix will be optimal.
  • Print
    Simone Sigrid Marticke.
    Print2008
    Status: Not Checked OutLane Catalog Record
  • Digital
    edited by Irene Burghardt, Stefan Haacke.
    Digital : CRCnetBASE2017
    Section I. Experiment -- Section II. Theory.
  • Digital
    Markus Braun, Peter Gilch, Wolfgang Zinth (eds.).
    Digital : Springer2008
    Ultrahigh-resolution optical coherence tomography using femtosecond lasers / J. G. Fujimoto ... [et al.] -- Two-photon laser scanning microscopy / A. Nimmerjahn, P. Theer, F. Helmchen -- Femtosecond lasers in ophthalmology: surgery and imaging / J. F. Bille -- Ultrafast peptide and protein dynamics by vibrational spectroscopy / P. Hamm -- Photosynthetic light-harvesting / T. Pullerits, T. Polivka, V. Sundström -- Primary photosynthetic energy conversion in bacterial reaction centers / W. Zinth, J. Wachtveitl -- Ultrafast primary reactions in the photosystems of oxygen-evolving organisms / A. R. Holzwarth -- Primary photochemistry in the photoactive yellow protein: the prototype xanthopsin / D. S. Larsen, R. van Grondelle, K. J. Hellingwerf -- Structure based kinetics by time-resolved X-ray crystallography / M. Schmidt -- Primary reactions in retinal proteins / R. Diller -- Ultrashort laser pulses in single molecule spectroscopy / E. Houstein, P. Schwille.
  • Digital
    Z.M. Seagal and O.V. Surnina.
    Digital : Wiley2016
    Topography and pathotopography of the head -- Topography and pathotopography of the neck -- Topographical and pathotopographical anatomy of the chest -- Topographical and pathotopographical anatomy of the abdomen -- Topographical and pathotopographical anatomy of the retroperitoneal space -- Topography and pathotopography of the pelvis -- Topography and pathotopography of lower extremity.
  • Digital
    edited by Botros R.M.B. Rizk, MD, FRCOG, FACOG, HCLD, FACS, FRCS(C), Professor of Obstetrics and Gynecology and Director of the Division of Reproductive Endocrinology and Infertility, University of South Alabama College of Medicine, Mobile, AL, USA, President Elect, Middle East Fertility Society, Elizabeth E. Puscheck, MD, MS, FACOG, Professor and Chair of the Department of Obstetrics and Gynecology, Director of Gynecologic Ultrasound, Wayne State University Medical School, Detroit, MI, USA.
    Digital : Cambridge2015
    Section 1. Techniques -- Section 2. Benign gynecology -- Section 3. Ectopic pregnancy -- Section 4. Gynecologic neoplasia -- Section 5. Ultrasonography in infertility.
  • Print
    [edited by] Peter W. Callen.
    Print2008
    Status: Not Checked OutLane Catalog Record
  • Digital
    Paula Ferrada, editor.
    Digital : Springer2015
    I. Basics of Ultrasound -- 1. The Machine -- 2. Frequency and probes -- 3. Common Artifacts -- 4. The Doppler Effect -- II. Thoracic Ultrasound -- 5. The Pleura -- 6. The Lung -- 7. Procedures -- 8. Cases -- III. Echocardiogram for the Intensivist -- 9. Rationale -- 10. Limited echocardiogram vs. full service echo -- 11. The Windows -- 12. The Measurements -- 13. The interpretation -- 14. Cases -- IV. Vascular Ultrasound in the Critically Ill -- 15. Deep Venous Thrombosis -- 16. Line Placement -- 17. Cases -- V. Basic Abdominal Ultrasound in the ICU -- 18. Evaluation for free fluid -- 19. Basic Renal ultrasound -- 20. Evaluation of the Gallbladder -- 21. Procedures -- 22. Cases -- VI. Soft Tissue -- 23. Facial Dehiscence -- 24. Soft tissue masses and collections -- VII. Other Issues -- 25. Training Challenges -- 26. Credentialing Process -- 27. Billing and Coding.
  • Digital
    Wilhelm Schäberle.
    Digital : Springer2011
    Fundamental principles -- Peripheral arteries -- Peripheral veins -- Shunts -- Extracranial cerebral arteries -- Visceral and retroperitoneal vessels -- Penile and scrotal vessels.
  • Digital
    Mirko D'Onofrio [editor] ; foreword by Claudio Bassi, Paolo Pederzoli.
    Digital : Springer2012
    Ultrasound Imaging / Anna Gallotti and Fabrizio Calliada -- Transabdominal Ultrasonography of the Pancreas / Elisabetta Buscarini and Salvatore Greco -- Endoscopic Ultrasonography of the Pancreas / Elisabetta Buscarini and Stefania De Lisi -- Percutaneous Ultrasound Guided Interventional Procedures in Pancreatic Diseases / Elisabetta Buscarini and Guido Manfredi -- Intraoperative Ultrasonography of the Pancreas / Mirko D'Onofrio, Emilio Barbi, Riccardo De Robertis, Francesco Principe and Anna Gallotti, et al. -- Pancreatic Anatomy, Variants and Pseudolesions of the Pancreas / Emilio Barbi, Salvatore Sgroi, Paolo Tinazzi, Stefano Canestrini and Anna Gallotti, et al. -- Pancreatitis and Pseudocysts / Steffen Rickes and Holger Neye -- Solid Pancreatic Tumors / Christoph F. Dietrich, Michael Hocke, Anna Gallotti and Mirko D'Onofrio -- Cystic Pancreatic Tumors / Mirko D'Onofrio, Paolo Giorgio Arcidiacono and Massimo Falconi -- Rare Pancreatic Tumors / Roberto Malagò, Ugolino Alfonsi, Camilla Barbiani, Andrea Pezzato and Roberto Pozzi Mucelli -- Imaging Correlation / Marie-Pierre Vullierme and Enrico Martone -- Pancreatic Lesions: Pathologic Correlations / Paola Capelli and Alice Parisi -- Clinical and Imaging Scenarios / Anna Gallotti and Riccardo Manfredi -- Flowcharts in Pancreatic Diseases / Elisabetta Buscarini.
  • Digital
    Ferdinando Draghi.
    Digital : Springer2014
    This practice-oriented book, containing a wealth of high-quality ultrasound images, provides clear, concise, and complete coverage of the normal anatomy of the hand and wrist - tendons, nerves, and vascular structures - as well as the main pathologic conditions encountered in this area. The ultrasound images have been acquired with state of the art scanners and carefully labeled to facilitate recognition of each and every anatomic structure. Helpful comparison is also made with images and findings obtained using other diagnostic techniques, including in particular magnetic resonance imaging. The lucid text is complemented by practical tables summarizing key points for ease of reference. Readers will find Ultrasonography of the Upper Extremity to be a rich source of information on anatomy, examination techniques, and ultrasound appearances of one of the anatomic regions to have benefited the most from the technological revolution that has taken place in the field of ultrasonography during recent years. The book will appeal to both novice and experienced practitioners, including above all radiologists and ultrasound technicians but also rheumatologists and orthopedic surgeons.
  • Digital
    [edited by] Günter Schmidt ; with contributions by B. Beuscher-Willems ... [et al.] ; [translator, Terry Telger].
    Digital : Thieme Book2007
    Digital : MedOne Radiology2007
    Basic physical and technical principles -- The ultrasound examination -- Ultrasound documentation and reporting -- Function studies -- Interventional ultrasound -- Principal signs and symptoms -- Arteries and veins -- Cervical vessels -- Liver -- Kidney and adrenal gland -- Pancreas -- Spleen -- Bile ducts -- Gallbladder -- Gastrointestinal tract -- Urogenital tract -- Thorax -- Thyroid gland -- Major salivary glands -- Postoperative ultrasound -- Search for occult tumors.
  • Digital
    Barbara S. Hertzberg, William D. Middleton.
    Digital : ClinicalKey2016
    This best-selling volume in The Requisites Series provides a comprehensive introduction to timely ultrasound concepts, ensuring quick access to all the essential tools for the effective practice of ultrasonography. Comprehensive yet concise, Ultrasound covers everything from basic principles to advanced state-of-the-art techniques. This title perfectly fulfills the career-long learning, maintenance of competence, reference, and review needs of residents, fellows, and practicing physicians. Covers the spectrum of ultrasound use for general, vascular, obstetric, and gynecologic imaging.
  • Digital
    Enzo Silvestri, Alessandro Muda, Davide Orlandi ; foreword by Nicola Maffulli.
    Digital : Springer2015
    The book provides a comprehensive description of the basic ultrasound principles, normal anatomy of the lower limb muscles and classification of muscle strain injures. Ultrasound images are coupled with anatomical schemes explaining probe positioning and scanning technique for the various muscles of the thigh and leg. For each muscle, a brief explanation of normal anatomy is also provided, together with a list of tricks and tips and advice on how to perform the ultrasound scan in clinical practice. This book is an excellent practical teaching guide for beginners and a useful reference for more experienced sonographers.
  • Digital
    Andrew Nicolaides, Kirk W. Beach, Efthyvoulos Kyriacou, Constantinos S. Pattichis, editors.
    Digital : Springer2012
  • Digital
    by Vladimir P. Kharchenko, Peter M. Kotlyarov, Mikhail S. Mogutov, Yury K. Alexandrov, Alexander N. Sencha, Yury N. Patrunov, Denis V. Belyaev.
    Digital : Springer2010
    As the basis for this book, the authors have analyzed more than 100,000 ultrasound examinations performed between 1995 and 2008 in patients with thyroid and parathyroid disease, as well as many thousands of diagnostic and therapeutic ultrasound-guided minimally invasive procedures. The opening chapters include discussion of current ultrasound techniques, pitfalls, and ultrasound examination of the thyroid in children. Detailed attention is then devoted to findings in the normal thyroid and in the presence of diffuse and focal changes.
  • Digital
    Guido Torzilli, editor.
    Digital : Springer2014
    Ultrasound guidance of liver surgery is a very sophisticated approach that permits the performance of otherwise unfeasible operations, discloses the true extent of tumors, increases the indications for hepatectomy, and renders surgery safer. Despite this, it has remained relatively neglected in the literature over the past two decades, during which time much progress has been achieved. This is the first atlas on the subject, and it is comprehensive in scope. The state of the art in the use of ultrasound for resection guidance is carefully documented, and new techniques for exploration of the biliary tract and facilitation of transplant surgery are presented. Further important topics include the role of ultrasound in laparoscopic approaches, the use of contrast agents for diagnosis and staging, and developments in the planning of surgical strategy. The editor is a leading authority whose group has been responsible for a variety of advances in the field. He has brought together other experts whose aim throughout is to provide clear information and guidance on the optimal use of ultrasound when performing liver surgery. This atlas is intended especially for hepatobiliary surgeons but will also be of considerable value for general surgeons.
  • Digital
    Gina Allen, David Wilson ; Salvador Beltran, illustrator.
    Digital : ClinicalKey2018
    "An ideal "how-to" guide for those who perform musculoskeletal injections, this unique multimedia resource by Drs. Gina M. Allen and David John Wilson demonstrates how to make the most out of the clear visualization provided by ultrasound-guided techniques. High-quality line drawings, clinical photographs, and ultrasound images clearly depict patient presentation, relevant anatomy, and sonoanatomy, and each technique is accompanied by a video showing exactly how to perform the procedure"--Publisher's description.
  • Digital
    Luca Maria Sconfienza, Davide Orlandi, Enzo Silvestri, editors.
    Digital : Springer2015
  • Digital
    Luca Maria Sconfienza, Giovanni Serafini, Enzo Silvestri, editors.
    Digital : Springer2012
    pt. 1. General Aspects of US-guided Musculoskeletal Procedures -- General Aspects of US-guided Musculoskeletal Procedures / Armando Conchiglia, Lorenzo Maria Gregori, Luigi Zugaro and Carlo Masciocchi -- pt. I. The Shoulder -- The Shoulder: Focused US Anatomy and Examination Technique / Enzo Silvestri and Davide Orlandi -- Subacromial-Subdeltoid Bursa Injections / Enzo Silvestri -- Treament of Calcific Tendinitis of the Rotator Cuff / Giovanni Serafini and Luca Maria Sconfienza -- Calcific Enthesopathy Dry-Needling / Francesca Lacelli -- Hyaluronic Supplementation of the Subacromial Space / Giovanni Serafini -- Intra-articular Injections / Francesca Lacelli -- Long Head of the Biceps Brachii Tendon Injection / Luca Maria Sconfienza -- Acromioclavicular Joint Injection / Enzo Silvestri -- pt. II. The Elbow -- The Elbow: Focused US Anatomy and Examination Technique / Enzo Silvestri and Emanuele Fabbro -- Treatment of Lateral Epicondylitis / Giovanni Serafini -- Treatment of Medial Epicondylitis / Enzo Silvestri -- Olecranon Bursa Drainage / Francesca Lacelli -- Intra-articular Injections / Luca Maria Sconfienza -- pt. III. The Wrist -- The Wrist: Focused US Anatomy and Examination Technique / Enzo Silvestri and Giulio Ferrero -- Treament of De Quervain's Disease and Other Forms of Tenosynovitis / Giovanni Serafini -- Articular Ganglia Drainage / Leonardo Callegari -- Trapeziometacarpal Joint Injection / Francesca Lacelli -- Radiocarpal Joint Injections / Luca Maria Sconfienza -- pt. IV. The Hand -- The Hand: Focused US Anatomy and Examination Technique -- Francesca Lacelli and Chiara Martini -- Treatment of Trigger Finger / Leonardo Callegari -- Intra-articular Injections: Metacarpophalangeal and Interphalangeal Joints / Luca Maria Sconfienza.
  • Digital
    Stuart A. Grant, David B. Auyong.
    Digital : Oxford Medicine Online2017
    This book provides a detailed, stepwise approach to performing ultrasound guided regional anesthesia, identifying pearls and pitfalls to ensure success. Basic principles are covered, followed by techniques for upper extremity, lower extremity, and chest, trunk and spine nerve blocks. Each nerve block is comprehensively explained, divided up by introduction, anatomy, clinical applications, technique, alternate techniques, complications, and pearls.
  • Digital
    editors, Paul E. Bigeleisen, Michael Gofeld, and Steven L. Orebaugh ; associate editors, Nizar Moayeri, Annelot Krediet, Gerbrand J. Groen, Stephen Breneman, Bassem Asaad, and Jacques E. Chelly.
    Digital : Ovid2015
  • Digital
    edited by Stephen Mannion, Gabriella Iohom, Christophe Dadure, Mark Reisbig, Arjunan Ganesh.
    Digital : Cambridge2015
    Performance of regional anesthesia in children / Arjunan Ganesh and Wallis T. Muhly -- Pharmacology of local anesthetics in children / Christina Van Horn and Mark D. Reisbig -- Management of complications / Immanuel Hennessy and Stephen Mannion -- Basics of ultrasonography for regional anesthesia in children / Christophe Dadure and Chrystelle Sola -- Anatomy of the neuraxis, thoracic, and abdominal walls, upper and lower limbs / Judith Barbaro-Brown and Gabriella Iohom -- Ultrasound guided axillary block in children / Pádraig O'Scanaill and Brian O'Donnell -- Ultrasound-guided supraclavicular brachial plexus block / Mark D. Reisbig -- Ultrasound guided infraclavicular brachial plexus block / Wallis T. Muhly and Arjunan Ganesh -- Ultrasound guided interscalene brachial plexus block / Harshad Gurnaney and Arjunan Ganesh -- Ultrasound guided femoral nerve block / Frédéric Duflo -- Ultrasound guided saphenous nerve block / Ahmed Abdel-Aziz and Amr Abdelaal -- Ultrasound guided sciatic nerve block / Anne-Charlotte Saour and Christophe Dadure -- Ultrasound guided ilioinguinal/iliohypogastric block / Sinead O'Shaughnessy and Charles Youngblood -- Transversus abdominis plane block / Eimhin Dunne and Brian O'Donnell -- Ultrasound guided rectus sheath block / Harshad Gurnaney and Arjunan Ganesh -- Ultrasound guided paravertebral block / Attila Bondár and Gabriella Iohom -- Ultrasound guided epidural anesthesia / Chrystelle Sola and Christophe Dadure -- Ultrasound for spinal anesthesia / Karthikeyan Kallidaikurichi Srinivasan and Peter Lee -- Ultrasound guided caudal block / Anca Grigoras and Jawad Mustafa -- Facial blocks / Chrystelle Sola and Christophe Dadure.
  • Digital
    João Miguel Sanches, Andrew F. Laine, Jasjit S. Suri, editors.
    Digital : Springer2012
    Ultrasound Imaging: Advances and Applications presents some of the recent advances in Ultrasound imaging technology covering several organs and techniques in a Biomedical Engineering (BME) perspective. The focus of the book is in the algorithms, methodologies and systems developed by multidisciplinary research teams of engineers and physicians for Computer-Aided Diagnosis (CAD) purposes. Cardiovascular and Cancer, the most common life-threatening diseases in western countries, are two of the most important topics focused in the book. However, other advanced issues are also presented such as Intravascular Ultrasound, 3D US and Ultrasound in Computer-Aided Surgery (CAS). Some chapters are direct contributions from medical research groups where Ultrasound has also received great attention in the last decade. By this, new techniques based on Ultrasound were introduced in the clinical practice for diagnosis and therapeutics, mainly in hospital facilities.
  • Digital
    volume editors Mario Meola, Ilaria Petrucci, Claudio Ronco.
    Digital : Karger2016
    Pathophysiology and clinical work-up of acute kidney injury / Meola, M., Nalesso, F., Petrucci, I., Samoni, S., Ronco, C -- Ultrasound in acute kidney disease / Meola, M., Nalesso, F., Petrucci, I., Samoni, S., Ronco, C -- Clinical scenarios in acute kidney injury : pre-renal acute kidney injury / Meola, M., Nalesso, F., Petrucci, I., Samoni, S., Ronco, C -- Clinical scenarios in acute kidney injury : hepato-renal syndrome / Meola, M., Nalesso, F., Petrucci, I., Samoni, S., Ronco, C -- Clinical scenarios in acute kidney injury : parenchymal acute kidney injury tubulo-interstitial diseases / Meola, M., Samoni, S., Petrucci, I., Ronco, C -- Clinical scenarios in acute kidney injury-parenchymal acute kidney injury, vascular diseases / Meola, M., Samoni, S., Petrucci, I., Ronco, C -- Clinical scenarios in acute kidney injury : post-renal acute kidney injury / Meola, M., Samoni, S., Petrucci, I., Ronco, C -- Imaging in chronic kidney disease / Meola, M., Samoni, S., Petrucci, I -- Clinical scenarios in chronic kidney disease : vascular chronic diseases / Meola, M., Samoni, S., Petrucci, I -- Clinical scenarios in chronic kidney disease : parenchymal chronic renal diseases, part 1 / Petrucci, I., Samoni, S., Meola, M -- Clinial scenarios in chronic kidney disease : parenchymal chronic renal diseases, part 2 / Petrucci, I., Samoni, S., Meola, M -- Clinical scenarios in chronic kidney disease : chronic tubulointerstitial diseases / Meola, M., Samoni, S., Petrucci, I -- Clinical scenarios in chronic kidney disease : cystic renal diseases / Meola, M., Samoni, S., Petrucci, I -- Clinical scenarios in chronic kidney disease : kidneys' structural changes in end stage renal disease / Meola, M., Samoni, S., Petrucci, I.
  • Digital
    Laurel A. Stadtmauer, Ilan Tur-Kaspa, editors.
    Digital : Springer2014
    Part I: Ultrasound Technique -- Ultrasound in Reproductive Medicine: Is It Safe?- Principles of 3D Ultrasound -- Two Dimensional and Three Dimensional Doppler in Reproductive Medicine -- Legal Aspects of Ultrasound Imaging in Reproductive Medicine -- Part II: Ultrasound in Infertility Workup -- The Normal Ovary -- Ovarian Reserve and Ovarian Cysts -- Ultrasound and PCOS -- The Normal Uterus -- Congenital Uterine Anomalies -- Uterine Fibroids -- Endometrial Polyps -- Intrauterine Adhesions -- Sonohysterography (SHG) in Reproductive Medicine -- Evaluation of Tubal Patency (HyCoSy, Doppler) -- Hydrosalpinx -- Virtual Hysterosalpingography: A New Diagnostic Technique for the Study of the Female Reproductive Tract -- Ultrasound in Male Infertility -- Part III: Ultrasound in Infertility Treatment -- Ultrasound in Follicle Monitoring for Ovulation Induction/IUI -- 2D Ultrasound in Follicle Monitoring for ART -- 3D Ultrasound in Follicle Monitoring for ART -- Ultrasound Guided Surgical Procedures -- Ultrasound Role in Embryo Transfers -- Ultrasound and Ovarian Hyperstimulation Syndrome -- Pregnancy of Unknown Viability -- Ultrasound Evaluation of Ectopic Pregnancy -- Focused Ultrasound for Treatment of Fibroids.
  • Print
    Ilan E. Timor-Tritsch, Steven R. Goldstein.
    Print2007
    Status: Not Checked OutLane Catalog Record
    Ultrasound in gynecology: development and continuing evolution -- Applied physics: selecting and adjusting the equipment -- Instrumentation, modality selection, and documentation -- Conducting the gynecologic ultrasound examination -- Relevant pelvic anatomy -- Adenomyosis -- Congenital uterine anomalies -- Adnexal masses -- Menopausal dilemmas: how ultrasound has changed clinical management -- Lower urinary tract -- Early pregnancy -- Pregnancy failure -- Ectopic pregnancy -- Infertility -- Sonohysterography -- Ultrasound-guided procedures in gynecology -- Color doppler mapping in gynecology -- Transvaginal sonography and ovarian cancer -- Three-dimensional ultrasound in gynecology -- Ultrasound-enhanced bimanual examination -- Differential diagnosis of inflammatory diseases of the pelvis -- Pearls and pitfalls of transvaginal sonography.
  • Digital
    [edited by] Eberhard Merz ; contributors F. Bahlmann ... [et al.]; [translator, Terry Telger].
    v. 1: Obstetrics
  • Digital
    Matthew Jankowich, Eric Gartman, editors.
    Digital : Springer2015
    Ultrasound in the Intensive Care Unit explores the current state of evidence supporting use of bedside ultrasound for procedural guidance and for the critical care-focused assessment of a variety of organ systems. This text covers standard practice areas, such as ultrasound guidance for vascular access in the ICU, as well as novel, less well-known applications such as the use of ultrasound for assessment of diaphragm function in patients with respiratory failure. As current ultrasound education is often dependent on widely varying local expertise, this book serves as a standard reference in what is at present a fragmented and challenging field of study for busy clinicians. By providing a comprehensive overview of the current state of critical care ultrasonography, with content contributed by experts in the field, this text will serve as a valuable resource that will allow education in critical care ultrasound to keep pace with the rapid technological growth that has driven this vital area of critical care medicine. Ultrasound in the Intensive Care Unit is essential reading for pulmonologists, practitioners in internal, hospitalist, and critical care medicine; educators and instructors in critical care ultrasound; and medical students, residents, and critical care trainees.
  • Digital
    Randy L. King.
    Digital2013
    Ultrasound-induced neurostimulation has recently gained increasing attention. Developments in the use of ultrasound to stimulate and modulate neural activity have raised the possibility of using ultrasound as a new investigative and therapeutic tool in brain research. Little is known about the mechanisms by which it affects neural activity or about the range of acoustic parameters and stimulation protocols that elicit responses. In this thesis, conditions are established for transcranial stimulation of the nervous system in vivo, using the mouse somatomotor response. It is reported that (1) continuous-wave stimuli are as effective as or more effective than pulsed stimuli in eliciting responses, and responses are elicited with stimulus onset rather than stimulus offset; (2) stimulation success increases as a function of both acoustic intensity and acoustic duration; (3) interactions of intensity and duration suggest that successful stimulation results from the integration of stimulus amplitude over a time interval of 50 to 150 ms; (4) the motor response elicited appears to be an all-or-nothing phenomenon, meaning stronger stimulus intensities and durations increase the probability of a motor response without affecting the duration or strength of the response; and (5) motor responses, measured by normalized EMG signals in the neck and tail regions, change signifcantly when sonicating rostral and caudal regions of the mouse motor cortex. Taken together our findings present good evidence for being able to target selective parts of the motor cortex with ultrasound neurostimulation in the mouse, steps that should provide encouragement for the development of new applications in larger animal models, including humans.
  • Digital
    G. Maconi, G. Bianchi Porro (eds.) ; with contributions by G. Bianchi Porro ... [et al.] ; foreword by A.L. Baert.
    Digital : Springer2007
  • Digital
    Giovanni Maconi, Gabriele Bianchi Porro, editors.
    Digital : Springer2014
    This is the second, updated and extended edition of a well-received book that offers a comprehensive overview of ultrasonographic imaging of acute and chronic gastrointestinal diseases, including acute abdomen, appendicitis, diverticulitis, inflammatory bowel diseases, neoplasms and masses, infections, malabsorption syndromes, and rare conditions. The value of ultrasound in each disorder is clearly explained and illustrated, and limitations identified. Information is also provided on recent technical developments and ultrasound applications that are likely to become of increasing importance, such as functional and 3D ultrasound, contrast agents and intraoperative ultrasound, elastography, and transperineal ultrasound. The authors are all distinguished experts in the topics they address. Ultrasound of the Gastrointestinal Tract will be a helpful guide in daily practice not only for radiologists but also for gastroenterologists, abdominal surgeons, pediatricians, and oncologists.
  • Digital
    Bruce R. Gilbert, editor.
    Digital : Springer2015
    History of Ultrasound -- Embryology Relevant to Ultrasound Imaging of the Male Genitalia -- Physical Principles of Ultrasound of the Male Genitalia -- Scrotal Ultrasound -- Penile Ultrasound -- Urology Ultrasound Practice Accreditation -- Genital Ultrasound Protocols: Putting it all Together!.
  • Digital
    Stefano Bianchi, Carlo Martinoli [editors] ; with contributions by L.E. Derchi ... [et al.] ; foreword by A.L. Baert ; introduction by I.F. Abdelwahab.
    Digital : Springer2007
  • Digital
    Robert A. Sofferman, Anil T. Ahuja, editors.
    Digital : Springer2012
    Section I. History and Basic Concepts -- The History of Clinical Ultrasound -- Physics and Principles of Ultrasound -- Practical Concepts of Ultrasound -- Section II. Thyroid and Parathyroid Glands -- Sonography of the Normal Thyroid -- Benign Thyroid Conditions -- Malignant Thyroid Conditions -- Ultrasound Surveillance -- Parathyroid Ultrasound -- Fine Needle Aspiration Cytology -- Section III. Lymph Nodes and the Neck -- Lymph Nodes -- Benign Clinical Conditions in the Adjacent Neck -- Section IV. New Advances in Applied Ultrasound -- Thyroid Elastography -- Percutaneous Ethanol Injection for Thyroid and Parathyroid Disorders -- Contrast Enhanced Ultrasound and Ultrasound-Guided Minimally Invasive Therapy for the Diagnosis and Treatment of Focal Thyroid Lesions.
  • Digital
    Ann M. Dvorak.
    Digital : Karger2005
    Print2005
  • Digital
    Shamim I. Ahmad, editor.
    Digital : Springer2017
    ""Dedication""; ""Preface""; ""Acknowledgment""; ""Contents""; ""About the Editor""; ""A Tribute to Aziz Sancar: The Nobel Prize Winner in Chemistry, 2015""; ""Part I: Introduction, Historical Aspects and Sources of UV Light""; ""1: History of UV Lamps, Types, and Their Applications""; ""1.1 Introduction""; ""1.2 The Discovery of UV Light""; ""1.3 The Types of UV Light""; ""1.4 Man-Made UV Generating Lamps""; ""1.4.1 Arc Lamp""; ""1.4.2 Cold-Light UV-A1""; ""1.4.3 Excimer""; ""1.4.4 Fluorescent Lamp""; ""1.4.5 Full Spectrum Light""; ""1.4.6 UV Gas Discharge Lamps"" ""1.4.7 Narrowband UVB""""1.4.8 Narrow Band Ultraviolet B and C Lamp""; ""1.4.9 Near UV or UVA Light""; ""1.4.10 Plasma and Synchrotron Sources of Extreme UV""; ""1.4.11 Microwave Discharge Electrodeless Lamp""; ""1.4.12 TL-01 Ultraviolet Lamp""; ""1.4.13 TL-12 Philips Lamp""; ""1.4.14 Black-Light ILTs""; ""1.4.15 UV Light-Emitting Diodes""; ""1.4.16 Ultraviolet Lasers""; ""1.4.17 UVA-1, UVA-2 and a Combination of Both""; ""1.4.18 Short Wave Ultraviolet Lamp""; ""1.5 Phototherapies""; ""1.5.1 UVA1 Phototherapy""; ""1.5.2 PUVA Therapy""; ""1.5.3 Photodynamic Therapy"" ""1.5.4 Extracorporeal Photopheresis""""1.6 Conclusion""; ""References""; ""Part II: UV Photoproducts, Damage to DNA and Mutagenesis""; ""2: Ultraviolet Light Induced Generation of Reactive Oxygen Species""; ""2.1 Introduction""; ""2.2 Ultraviolet Light""; ""2.2.1 The Global Solar UV Index (UVI)""; ""2.3 Sources of UV Light""; ""2.3.1 Outdoor""; ""2.3.2 Artificial Sources""; ""2.4 Tissue Exposure to UV""; ""2.5 UV Light Induced Reactive Oxygen Species""; ""2.5.1 What Are Reactive Oxygen Species?""; ""2.5.2 UV â#x80;#x93; Light Induced ROS""; ""2.5.2.1 Catalase"" ""2.5.2.2 Nitric Oxide Synthase""""2.5.2.3 Signalling Pathways""; ""2.5.2.4 Protein Kinase C""; ""2.5.2.5 DNA Damage""; ""2.5.3 Biochemical Actions of UV in the Skin""; ""2.6 UV, ROS and Pathophysiological Skin Effects""; ""2.7 Conclusion""; ""References""; ""Part III: UV Light and Human Diseases""; ""3: UV-Induced Molecular Signaling Differences in Melanoma and Non-­melanoma Skin Cancer""; ""3.1 UVR Impact on NMSC""; ""3.1.1 Introduction""; ""3.1.2 UVB-Caused DNA Damage in Keratinocytes and Basal Cells""; ""3.1.3 The DNA Repair Mechanisms""; ""3.1.3.1 The NER System"" ""3.1.3.2 The BER System""""3.1.4 UVR and Mutations""; ""3.1.4.1 The p53 Gene""; ""3.1.4.2 PTCH (PATCHED1)""; ""3.1.4.3 PTEN""; ""3.1.4.4 RAS Oncogenes""; ""3.1.4.5 Cell Cycle Genes and HPV Virus Infection""; ""3.1.5 UVR-Induced Immunosuppression""; ""3.1.5.1 The Fas/FasL System""; ""3.1.5.2 Langerhans Cells""; ""3.1.5.3 Natural Killer Cells and Master Cells""; ""3.1.5.4 Cyclooxygenase (COX-2)""; ""3.2 The UV Impact on Melanoma""; ""3.2.1 The UVR-Induced DNA Damage in Melanoma""; ""3.2.1.1 The MAP Kinase Pathway: NRAS and BRAF Oncogenes""
  • Digital
    Giuseppe Biondi-Zoccai, editor.
    Digital : Springer2016
    1 Evidence hierarchy -- 2 From qualitative reviews to umbrella reviews -- 3 Umbrella reviews, overviews of reviews, meta-epidemiologic studies: similarities and differences -- 4 Designing the review -- 5 Registering the review -- 6 Searching evidence -- 7 Abstracting evidence -- 8 Appraising evidence -- 9 Synthesizing evidence -- 10 Appraising moderators and confounders -- 11 State of the art reporting -- 12 Case study in anesthesiology and intensive care -- 13 Case study in basic research -- 14 Case study in cardiovascular disease -- 15 Case study in dermatology -- 16 Case study in oncology -- 17 Case study in radiology -- 18 Case study in surgery -- 19 Moving from evidence to action -- 20 Avenues for further research -- 21 Conclusion.
  • Print
    Neumann, Erich.
    Status: Not Checked OutLane Catalog Record
    -- v. 2. Zur Psychologie des Weiblichen.
  • Digital
    Digital2009
  • Digital
    [edited by] Darcy Umphred [and others].
    Digital : ClinicalKey2013
    Section I. Foundations for clinical practice in neurological rehabilitation. Foundations for clinical practice / Darcy A. Umphred, Rolando T. Lazaro and Margaret L. Roller -- Health and wellness: The beginning of the paradigm / Janet R. Bezner -- Movement analysis across the life span / Dale Scalise-Smith and Darcy A. Umphred -- Contemporary issues and theories of motor control, motor learning, and neuroplasticity / Margaret L. Roller ... [et.al.] -- The limbic system : Influence over motor control and learning / Darcy A. Umphred, Marcia Hall Thompson and Therese Marie West -- Psychosocial aspects of adaptation and adjustment during various phases of neurological disability / Rochelle McLaughlin and Gordon U. Burton -- Differential diagnosis phase 1 : Medical screening by the therapist / William G. Boissonnault and Darcy A. Umphred -- Differential diagnosis phase 2 : Examination and evaluation of functional movement activities, body functions and structures, and participation / Rolando T. Lazaro, Margaret L. Roller and Darcy A. Umphred -- Interventions for clients with movement limitations / Darcy A. Umphred ... [et.al.] -- Payment systems for services : Documentation through the care continuum / Barbara Edmison and John G. Wallace, Jr. -- Section II. Rehabilitation management of clients with neurological system pathology. Neonates and parents : Neurodevelopmental perspectives in the neonatal intensive care unit and follow-up / Jane K. Sweeney, Teresa Gutierrez and Joanna C. Beachy -- Management of clinical problems of children with cerebral palsy / Claudia R. Senesac -- Genetic disorders : A pediatric perspective / Sandra G. Bellamy and Eunice Yu Chiu Shen -- Learning disabilities and developmental coordination disorder / Stacey E. Szklut and Darbi Breath Philibert -- Spina bifida : A congenital spinal cord injury / Kristin J. Krosschell and Mari Jo Pesavento -- Traumatic spinal cord injury / Myrtice B. Atrice ... [et.al.] -- Neuromuscular diseases / Ann Hallum and Diane D. Allen -- Beyond the central nervous system : Neurovascular entrapment syndromes / Bradley W. Stockert, Laura J. Kenny and Peter I. Edgelow -- Multiple sclerosis / Gail L. Widener -- Basal ganglia disorders / Marsha E. Melnick -- Movement dysfunction associated with cerebellar damage / Susanne M. Morton and Amy J. Bastian -- Balance and vestibular dysfunction / Leslie K. Allison and Kenda Fuller -- Movement dysfunction associated with hemiplegia / Susan D. Ryerson -- Traumatic brain injury / Patricia A. Winkler -- Brain tumors / Corrie J. Stayner, Rachel M. Lopez and Karla M. Tuzzolino -- Inflammatory and infectious disorders of the brain / Judith A. Dewane -- Aging, dementia, and disorders of cognition / Osa Jackson Schulte, James Stephens and Joyce Ann -- Section III. Neurological disorders and applications issues. Disorders of vision and visual-perceptual dysfunction / Laurie Ruth Chaikin -- Pelvic floor treatment of incontinence and other urinary dysfunctions in men and women / Beate Carriere -- Cardiovascular and pulmonary system health in populations with neurological disorders / Marilyn Mackay-Lyons -- Human immunodeficiency virus infection : Living with a chronic illness / Kerri Sowers, Mary Lou Galantino and David M. Kietrys -- Pain management / Annie Burke-Doe -- Electrophysiological testing and electrical stimulation in neurological rehabilitation / Alain Claudel ... [et.al.] -- Orthotics : Evaluation, intervention, and prescription / Heidi Truman and Walter Racette -- Management of chronic impairments in individuals with nervous system conditions / Myla U. Quiben -- Impact of drug therapy on patients receiving neurological rehabilitation / Annie Burke-Doe and Timothy J. Smith -- Use of medical imaging in neurorehabilitation / Rolando T. Lazaro and Darcy A. Umphred -- Integrating technology into clinical practice in neurological rehabilitation / Katie Byl ... [et.al.] -- Complementary and alternative therapies : Beyond traditional approaches to intervention in neurological diseases and movement disorders / Darcy A. Umphred, Carol M. Davis and Mary Lou Galantino.
  • Digital
    Pierre Le Béguec, François Canovas, Olivier Roche, Mathias Goldschild, Julien Batard.
    Digital : Springer2015
    Part I: Press-Fit Concept -- Uncemented Concepts: Parameters to Make a Choice -- The Press-Fit Concept: Principles and Press-Fittable Zones -- The Press-Fit Concept: Practical Application -- The Press-Fit Concept: Implants And Instruments -- Part II: Preoperative Planning -- Radiographic Analysis Of The Femur -- Selection of a Strategy -- Making a Preoperative Template -- Part III: Surgical Technique -- Trochantero-Diaphyseal Femoral Flap -- Femoral Flap and Diaphyseal Primary Fixation -- Endofemoral Approach and Proximal Primary Fixation -- Part IV: Evaluation of the Radiographic Results -- General Considerations -- A-Evaluation of the Radiographic Results ? How? -- Evaluation of Initial and Secondary Bone Stock -- Evaluation of Osseointegration and Secondary Stability -- Global Radiographic Score -- Comparative Elements with the Engh Score -- Part V: Evaluation of the Radiographic Results -- Why? -- The Learning Curve and its Teachings -- Different Types of Primary Stability: Their Impact on the Radiographic Results -- Degree of Osteoporosis: Its Impact on the Radiographic Results -- Affected Initial Bone Stock: Its Impact on the Radiographic Results -- Parameters to Improve Radiographic Results -- Complications and Contraindications -- Numerical Evaluation and Comparative Analysis of Results -- General Conclusions: What You Should and What You Should not Do.
  • Digital
    Digital : WHO2008
    Print2008
    Part 1: Guidance document on characterizing and communicating uncertainty in exposure assessment -- Part 2: Hallmarks of data quality in chemical exposure assessment.
  • Print
    edited by Louis R. Caplan ; founding editor, Julien Bogousslavsky.
    Print2008
    Status: Not Checked OutLane Catalog Record
  • Digital
    Marc Leone, Claude Martin, Jean-Louis Vincent, editors.
    Digital : Springer2014
    This book highlights the practical characteristics of uncommon diseases and presents the most relevant features for the management of intensive care units. It does not aim to provide an exhaustive description of uncommon diseases, focusing instead on the major diseases that intensivists may encounter in their clinical practice. After a brief introduction on the epidemiology and pathophysiology of each disease, the authors emphasize the aspects related to diagnosis and treatment, providing concise and pragmatic guidance for residents and intensivists who care for patients with uncommon diseases. Although by definition uncommon diseases have a low prevalence in the general population, they can affect a large number of patients admitted to intensive care units, as they can often be diagnosed at intensive care units. Indeed, often a complication of the disease is what leads to the patient's being admitted to an intensive care unit.
  • Digital
    Paolo Pederzoli, Claudio Bassi, editors ; in collaboration with Massimo Falconi, Roberto Salvia and Giovanni Butturini ; foreword by Gianluigi Melotti.
    Digital : Springer2013
    Cystic Pancreatic Neoplasms -- Classification / Giuseppe Zamboni -- Serous Cystic Neoplasms / Giuseppe Malleo, Giuseppe Zamboni, Marina Paini, Giovanni Marchegiani -- Mucinous Cystic Neoplasms / Giovanni Marchegiani, Riccardo Manfredi, Giuseppe Malleo, Isabella Frigerio -- Solid-pseudopapillary, Acinar, and Other Cystic Neoplasms / Marina Paini, Giuseppe Zamboni, Riccardo Manfredi, Salvatore Paiella, Giuseppe Malleo -- Intraductal Papillary Mucinous Neoplasms / Isabella Frigerio, Giuseppe Zamboni, Riccardo Manfredi, Antonio Pea, Silvia Pennacchio -- The Role of the Oncologist in the Diagnosis and Management of Malignant Cystic Neoplasms / Alessandra Auriemma, Davide Melisi, Giampaolo Tortora -- Neuroendocrine Pancreatic Neoplasms -- Epidemiology and Clinical Presentation / Maria Vittoria Davì, Marco Toaiari, Giuseppe Francia -- Pathology and Genetics / Aldo Scarpa, Vincenzo Corbo -- Imaging / Roberto Pozzi Mucelli, Giovanni Foti, Luigi Romano -- Surgical Therapy / Rossella Bettini, Stefano Partelli, Stefano Crippa, Letizia Boninsegna, Massimo Falconi -- Functional Imaging and Peptide Receptor Radionuclide Therapy / Maria Chiara Ambrosetti, Duccio Volterrani, Federica Guidoccio, Lisa Bodei -- Targeted and Other Non-receptor-mediated Therapies / Sara Cingarlini, Chiara Trentin, Elisabetta Grego, Giampaolo Tortora -- Uncommon Pancreatic Solid Neoplasms -- Rare Variants of Ductal Adenocarcinoma of the Pancreas / Paolo Regi, Marco Dal Molin, Federica Pedica, Paola Capelli, Mirko D'Onofrio -- Rare Primary Tumors of the Pancreas / Marco Dal Molin, Paola Capelli, Mirko D'Onofrio, Ivana Cataldo, Giovanni Marchegiani -- Rare Secondary Tumors of the Pancreas / Giovanni Butturini, Marco Inama, Marco Dal Molin, Mirko D'Onofrio, Davide Melisi -- Primary Non-epithelial Tumors of the Pancreas / Marco Dal Molin, Paola Capelli -- Tumor-like Lesions of the Pancreas / Luca Frulloni, Antonio Amodio, Italo Vantini, Marco Dal Molin, Marco Inama.
  • Digital
    Jennifer Judson Esch.
    Digital2015
    One important goal of the nervous system is to allow an animal to formulate an appropriate response to external stimuli. Doing so often requires both prediction of future events and comparison of expected outcomes to observed outcomes. The detection of visual motion can subserve both of these goals. Determining the speed and direction of a moving object--be it prey, predator, or a conspecific--allows an animal to predict where this target will likely be in the near future. Such a calculation can be essential to allowing the animal to eat, to avoid being eaten, or to successfully reproduce. Because of these many important uses for motion information, directional calculations are an early and essential task of the visual systems across animal phyla. Both psychophysical and physiological study has been used to try to understand what motion computations are performed by different visual systems and how these computations are implemented within neural circuits. Flies specifically and insects more generally have been used as model systems for the study of motion vision for over 60 years, with many theories about motion vision being advanced through intensive behavioral characterization and recordings from large motion-selective neurons accessible to electrophysiology. Over the past several years, the development of genetic tools has enabled direct identification of many of the neurons that play key roles in the processing of visual input to generate direction-selective neuronal responses and motion-guided visual behaviors. These recent studies have shown that motion-processing in the fly is split into separate pathways for moving light edges and moving dark edges at the level of second-order neurons (Joesch, Schnell, et al., 2010; Silies et al., 2013) and have shown that several third-order neurons have structural spatial offsets and temporal response properties appropriate to serve in the generation of direction-selective responses (Takemura, Bharioke, et al., 2013; Behnia et al., 2014; Shinomiya et al., 2014). Most significantly, these genetic tools have allowed for the identification of the first-direction selective neurons in the fly brain: T4 and T5 (Maisak et al., 2013). Prior to this work, the T4 and T5 neurons had been demonstrated to be direction- selective, edge-polarity selective, and orientation-selective, but the exact contrast comparisons and algorithm that they implemented to lead to such selectivity was unknown (Maisak et al., 2013; Fisher, Silies, and Clandinin, 2015). We set out to identify the algorithm that is implemented in the T4 and T5 neurons that leads to their stimulus selectivity. In this study, both functional segmentation (Chapter 2) and genetic tools are used isolate the visually-evoked activity of the first neurons in the fly visual system to exhibit direction selectivity (Chapter 3). The responses of single units are then used to fit a stimulus-response model that elucidates the functional computations accounting for the direction-selective responses of these neurons. This model places specific constraints on the contribution of synaptic inputs to these direction-selective neurons. Finally, as part of an ongoing effort to assign specific neurons to particular processing steps leading to the visual algorithm implemented by T4 and T5, preliminary experiments that aim at understanding the unique contributions of different early visual inputs are described (Chapter 4).
  • Digital
    Natasha Meyer O'Brown.
    Digital2015
    Understanding the molecular and genomic events responsible for adaptation is a major goal of evolutionary genetics. With recent advances in sequencing technology, it has now become possible to compare genomes across taxa and uncover the genetic lesions that differentiate populations and species. One of the most distinctive traits that differs between marine and freshwater sticklebacks is the number of bony lateral plates along their flanks. While marine fish tend to have 32 armor plates, most freshwater fish have reduced this number to 7 or less. This reduction in armor plates has previously been mapped to expression changes in the ectodysplasin (EDA) gene (Colosimo et al, 2005). We now have a complete threespine stickleback (Gasterosteus aculeatus) reference genome, along with several additional genomes from various marine and freshwater populations (Jones et al, 2012). The work in this thesis uncovers an armor plate enhancer that lies downstream of EDA and regulates EDA expression in the developing armor plates. Within this enhancer lies a single base pair change that is shared between all low-plated freshwater fish. Altering this single base in the enhancer changes the domain of enhancer activity by restricting activity to the anterior armor plates that remain in freshwater fish. Furthermore, this thesis goes on to show that the restricted domain of enhancer activity in freshwater fish is due to diminished Wnt responsiveness. Whole genome sequencing projects have also identified genomic differences that separate humans and chimpanzees (Chimpanzee Sequencing and Analysis Consortium, 2005). The rapid and dramatic expansion of the human brain is one of the most distinctive traits that separates us from chimpanzees, yet little is known about the genetic basis for human-specific cortical expansion. Using a comparative genomics approach, our lab previously identified 510 genomic locations where highly conserved regulatory sequences had been specifically lost in the human lineage. One of these locations is a gene rich-region on chimpanzee chromosome 7q22 previously associated with tumor suppressor activity. By cloning the ancestral sequence into a basal promoter-LacZ construct, we have shown that the highly conserved sequence normally serves as an enhancer that drives expression specifically in progenitor cells of the developing forebrain during the critical periods of cortical neurogenesis. In order to functionally test the effects of losing this sequence in the human lineage, we have generated "humanized" knockout mice that are missing the same regulatory sequence. Using RNA-sequencing and ATAC-sequencing to compare knockout to wildtype littermates, I have found that deletion of this enhancer element significantly changes the expression of hundreds of genes, including genes located both nearby and far away from the human deletion, and also alters the local chromatin landscape. The genes with increased expression in mutant embryonic brains are highly enriched for cell division and proliferation functions. I have found that deletion homozygous mice are viable and fertile, and show increased cortical neuron and astrocyte numbers in adult cortex and hippocampus. Gene expression and genetic complementation studies indicate that many of the phenotypes in the knockout mice are due to altered regulation of a gene flanking the deletion that encodes N-acyl phosphatidyl ethanolamine phospholipase D (Napepld). Interestingly, homozygous enhancer knockout mice with increased neuron and glia numbers also show behavioral improvement in memory and learning as measured by the Morris water maze. Collectively, these experiments provide new insights into the genomic and developmental events underlying human brain development and evolution.
  • Digital
    Jana Schaich Borg.
    Digital2012
    Over half of all violent crimes are committed by only about 5% of offenders. While most healthy people feel strong aversion to seeing other people in pain, fear, or sadness, a phenomenon I define as "negative intersubjectivity", these persistent violent offenders (PVOs) have blunted reactions to other people's distress and the strength of their negative intersubjectivity deficit correlates with how much violence they ultimately perform. This suggests that if we could learn how to enhance PVOs aversion to other people's distress, we could decrease their violent behavior. In this dissertation, I describe a new rat model that can be used to study the neural mechanisms underlying negative intersubjectivity. I demonstrate that Observer rats will overcome their innate aversion of bright light to consistently avoid a dark, safe space if entering that dark space is paired with another Receiver rat getting shocked, a behavior called "intersubjective avoidance". In Chapter 2, I describe the relatively poor intersubjective avoidance behavior of mice. In Chapter 3, I describe the comparatively strong intersubjective avoidance behavior of rats, and show that rats' intersubjective avoidance is enhanced by personal experience with shock. In Chapter 4, I use patterns of expression of the immediate early gene c-Fos to determine whether activity in candidate brain regions correlates with intersubjective avoidance. I provide evidence that many brain regions--including the anterior cingulate, anterior insula, infralimbic cortex, and central amygdala--are active both when observing shock in another and when receiving shock to oneself, similar to what has been shown by fMRI studies of humans observing others in pain. However, within these areas, only activity in the anterior cingulate robustly correlates with how much intersubjective avoidance each individual Observer rat performs, perhaps analogous to how fMRI studies in humans have show that anterior cingulate activity correlates with humans' self-reports of "empathy". These results validate the rat model of intersubjective avoidance as model of negative intersubjectivity in humans, and highlight the anterior cingulate as a potential target for negative intersubjectivity interventions. In Chapter 5, I describe future experiments and discuss how research using this new behavioral paradigm may help develop treatments for not only PVOs, but all anti-social behavior.
  • Digital
    Ekaterina Neklyudova.
    Digital2012
    My dissertation deals with the figure of the doctor in early Russian nineteenth-century prose, which manifests a shift in the way literature depicts human physicality and the characters' everyday life. My major source is 1820s-1840s prose, mostly published in the literary and cultural journals Biblioteka dlia Chtenia, Syn Otechestva, and others. My sources reflect the impressive expansion in Russian literature and medicine in the first quarter of the nineteenth century. Using documentary and literary sources, I demonstrate that the artistic representation of physicians in Romantic and Realist prose contributes to the introduction of previously unknown themes into literature: medical perspectives on physical suffering, the private everyday lives of ordinary people, and even the mystical view of other worlds. The combination of medical and mystical discourses in the vocabulary of real doctors in the first half of the nineteenth century gave them the authority to judge human bodies, lives, and, they believed, souls: they seemed to observe from inside and outside at the same time. By including a doctor among their characters, fiction writers thus could use a powerful instrument that let them introduce new topics. As I show, through the mid nineteenth century, the fictional doctors situated at the margin of literary plots performed the role of an important textual device: they served as go-betweens among other characters, mediating, connecting or splitting them. They affected the relationship between characters, the plot's trajectory, and the readers' perception. The situation shifts in mid century; with the gradual separation of doctor from his instrumental function, this character moves to the center of the plot and loses his structural power.
  • Digital
    Michael B. Chancellor, Ananias C. Diokno, editors.
    Digital : Springer2016
    Epidemiology and Demographics of Underactive Bladder -- Evaluation and Diagnosis of Underactive Bladder.-Urodynamic Evaluation of Underactive Bladder -- Pathophysiology of UAB and Animal Modeling -- Nonsurgical Therapy; Catheters; Devices -- Current Drug Therapy for Underactive Bladder -- Novel Drugs for Underactive Bladder -- Neuromodulation Treatment of Underactive Bladder -- Surgery for Underactive Bladder Treatment -- Advance Technology -- Diabetes and Other Neurogenic Underactive Bladder -- Geriatric Urology and Underactive Bladder -- Pediatrics UAB -- Public Health and Advocacy for Underactive Bladder. Appendix 1: Guide to Underactive Bladder Care -- Appendix 2: Resources to Underactive Bladder Care.-.
  • Digital
    by Thomas Bonk.
    Digital : Springer2008
  • Print
    Charles Henry Brase, Corrinne Pellillo Brase.
    Print2012
    Status: Not Checked OutLane Catalog Record
    1. Getting Started -- 2. Organizing Data -- 3. Averages and Variation -- 4. Elementary Probability Theory -- 5. The Binomial Probability Distribution and Related Topics -- 6. Normal Curves and Sampling Distributions -- 7. Estimation -- 8. Hypothesis Testing -- 9. Correlation and Regression -- 10. Chi-Square and F Distributions -- 11. Nonparametric Statistics.
  • Digital
    the National Center on Addiction and Substance Abuse at Columbia University.
    Digital2016
    This white paper reviews and summarizes hundreds of scientific research papers by leading experts in the fields of addiction, eating disorders, obesity and nutrition to lay out the shared characterizing symptoms, risk factors and underlying neurobiological characteristics between food and substance addiction. It describes the differences between food addiction and binge eating disorder (now an official psychiatric diagnosis). It offers evidence-based recommendations for policy, prevention, health care practice and research, and offers informative resources for further examination of this emergent area of work. Finally, it highlights how the knowledge and experience gained from years of research, prevention and intervention work in tobacco, alcohol and other drug control might be applied to controlling another leading threat to the public health: unhealthy eating, overweight and obesity. The National Center on Addiction and Substance Abuse looks forward to contributing to this body of research and policy work through its new program at Yale under the direction of Dr. Carlos Grilo.
  • Digital
    Magdy El-Salhy, Jan Gunnar Hatlebakk, Trygve Hausken.
    Digital : Springer2015
    1. Irritable bowel syndrome: what is it? -- 2. The digestive tract and how it works -- 3. The cause of irritable bowel syndrome -- 4. How is irritable bowel syndrome diagnosed? -- 5. Treatment options without medication -- 6. Treatment options involving medication -- 7. There is a light at the end of the tunnel.
  • Digital
    Chad Michael Whitman.
    Digital2010
    The mammalian cell surface is comprised of a heterogenous mixture of proteins and lipids decorated by carbohydrates. These molecules are known as glycoconjugates. Among the many types of glycolipids imbedded within the plasma membrane is a class of negatively charged species known as gangliosides. Gangliosides, which are characterized by the presence of sialic acid residues, are responsible for regulating the activity of many cell surface proteins and serve as recognition targets for cell-cell communication and pathogen invasion. To investigate the biological roles of gangliosides in mammalian cells, I have employed metabolic oligosaccharide engineering techniques to introduce small structural changes into sialic acid residues. Using these methods, I have successfully demonstrated the biosynthesis of photocrosslinking gangliosides in mammalian cells. These photocrosslinking gangliosides can be used to capture and isolate transient ganglioside-mediated interactions in their native environment. I have also used metabolic engineering techniques to probe the substrate selectivity of ganglioside sialyltransferases in mammalian cells. My results illustrate significant differences in the ability of different cell lines to metabolize sialic acid analogs; these differences may be due species-specific variations in sialyltransferase specificity.
  • Digital
    Yen Ling Adelene Sim.
    Digital2012
    RNA is an important biological macromolecule that carries out a variety of roles in the cell. To function, RNA needs to fold into precise three-dimensional structures. Different physical forces like entropy, base-pairing and stacking interactions, tertiary contacts and electrostatics affect this folding process. In the first part of this thesis, we focus on nucleic acid electrostatics; RNA molecules have negatively charged backbones that require counterions to neutralize charge-repulsion and facilitate folding. We discuss the ion conditions necessary for a riboswitch (gene-regulating RNA found on 5' or 3' ends of messenger RNA) folding, studied how the flexibility of single stranded DNA is affected by the presence of different amounts of counterions and present a benchmark experimental dataset that can be used for direct comparison to electrostatic theories. The second part of the thesis deals with computational and analysis tools developed to model and understand nucleic acid systems with the ultimate goal of being able to predict RNA structure. Since RNA typically folds hierarchically, we devised a general hierarchical sampling protocol that naturally explores RNA three-dimensional conformational space efficiently and can be used in concert with any force field, such as an RNA knowledgebased potential that we also discuss in this thesis. Additionally, we examined a clustering method that can assist analysis of structural models. Lastly, we applied our modeling techniques to study simple two-way RNA junctions with all-atom representation, and probed the modeled effects of sterics, chain connectivity and sequence on dynamic RNA behavior.
  • Digital
    Ariel Veronica Dowling.
    Digital2011
    The overall goal of this dissertation is to use novel motion analysis systems to investigate the underlying mechanisms that cause an anterior cruciate ligament (ACL) injury and then to explore movement modification methods that might prevent ACL injuries from occurring. Additionally, novel motion analysis systems can provide new information about ACL injuries and therefore should be used to help analyze these injuries from a different perspective. This thesis provides the results from multiple experimental studies that used two novel motion analysis systems to investigate the underlying causes of ACL injury and potential injury prevention methods. Using a markerless motion capture system, the first investigation determined that increasing the coefficient of friction of the shoe-surface condition will change a subject's movement strategies during a sidestep cutting task in specific ways that may increase the risk of ACL injury. This investigation provides a biomechanical basis for the increased incidence of ACL injuries on high friction surfaces, and suggests that females are more at risk for ACL injury when cutting on high friction surfaces. In terms of novel motion analysis systems, there is a need for simple, cost effective methods to identify athletes at a higher risk for ACL injury during jumping tasks. As such, the second study assessed the capacity of a wearable inertial-based system to evaluate ACL injury risk during jumping tasks. The proposed system measured the knee flexion angle and the trunk lean, and demonstrated good concurrent validity and discriminative performance in terms of the known risk factors for ACL injury. This study also reported the angular velocity of the thigh and shank segments during bilateral and unilateral drop jumps for the first time. Furthermore, this study illustrated that there is an association between the coronal segment angular velocity and knee abduction moment, and that the coronal segment angular velocity can differentiate between subjects at higher risk for ACL injury. Recent studies have shown that the incidence of ACL injury can be decreased through the use of intervention programs. Therefore, the objective for the final study was to determine if an independent inertial-based system can be used to modify jump landing mechanics in order to decrease the risk for ACL injury by providing real-time feedback based on known kinematic and kinetic injury risk factors. This study found that the subjects reduced their risk for ACL injury after training with the system because there were significant increases in the maximum knee flexion angle and the maximum trunk lean. The subjects also reduced their risk for injury by decreasing their thigh coronal angular velocity, which was correlated with a decrease in their knee abduction moment. This study suggests that an inertial-based system could be used for interventional training aimed at reducing the risk for ACL injury.
  • Digital
    edited by Sue Ziebland, Angela Coulter, Joseph D. Calabrese, and Louise Locock.
    Digital : OSO2013Limited to 3 simultaneous users
    Improving patient experience is a global priority for health policy-makers and care providers. This book critically examines the various ways in which people's experience of health and healthcare can be recorded, analysed and therefore improved.
  • Digital
    Digital : WHO2014
    Print2014
    "Surveillance data collected in vital registration and TB notification systems provide essential information about the TB epidemic and programmatic efforts to control the disease at both national and local levels. Analysis of these data can help programme managers and other staff to track the level of and trends in TB disease burden, detect outbreaks of disease and identify ways to improve existing TB prevention, diagnostic and treatment services. This book provides practical guidance on the analysis and use of such surveillance data, and is suitable for a wide range of people engaged in TB control. It was produced as a major collaborative effort as part of the work of the WHO's Global Task Force on TB Impact Measurement."-- back cover.
  • Print
    Jerry A. Dorsch, Susan E. Dorsch.
    Print2008
    Status: Not Checked OutLane Catalog Record
    This text once again takes readers step-by-step through all the basic anesthesia equipment. It includes comprehensive references and detailed discussions on the scientific fundamentals of anesthesia equipment, its design, and its optimal use. This thoroughly updated edition includes new information on suction devices, the magnetic resonance imaging environment, temperature monitoring and control, double-lumen tubes, emergency room airway equipment, and many other topics.
  • Print
    guest editors: John G. Bartlett, Dale N. Gerding.
    Print2008
  • Digital
    [edited by] Luca Mainardi, Leif Sörnmo, Sergio Cerutti.
  • Digital
    Thokozani Majozi, E R Seid, and J-Y Lee.
    Digital : CRCnetBASE2017
    Chapter 1. Introduction to batch processes -- Chapter 2. Modelling for effective solutions: reduction of binary variables -- Chapter 3. Methods to reduce computational time: prediction of time points -- Chapter 4. Integration of scheduling and heat integration: minimization of energy requirements -- Chapter 5. Heat integration in multipurpose batch plants -- Chapter 6. Design and synthesis of heat-integrated batch plants using an effective technique -- Chapter 7. Simultaneous scheduling and water optimization: reduction of effluent in batch facilities -- Chapter 8. Optimization of energy and water use in multipurpose batch plants using an improved mathematical formulation -- Chapter 9. Targeting for long-term horizons: water optimization -- Chapter 10. Long-term heat integration in multipurpose batch plants using heat storage -- Index.
  • Digital
    William M. Baum.
    Digital : Wiley2017
    What is behaviorism? -- Behaviorism : definition and history -- Behaviorism as philosophy of science -- Public, private, natural, and fictional -- A scientific model of behavior -- Evolutionary theory and reinforcement -- Purpose and reinforcement -- Stimulus control and knowledge -- Verbal behavior and language -- Rule-governed behavior and thinking -- Freedom -- Responsibility, credit, and blame -- Relationships, management, and government -- Values : religion and science -- The evolution of culture -- Design of culture : experimenting for survival.
  • Print
    Marketa Zvelebil & Jeremy O. Baum.
    Print2008
    Status: Not Checked OutLane Catalog Record
  • Digital
    edited by Sylvie E. Blondelle.
    Digital : Springer2006
  • Digital
    Melanie Diane Fox.
    Digital2011
    Many children with cerebral palsy walk with a stiff knee gait, or a reduction and delay in swing phase knee flexion, which causes tripping or energy-inefficient compensatory movements. Since over-activity of the rectus femoris muscle is frequently implicated as the cause, a common treatment is transfer of the distal end of the rectus femoris from its insertion on the patella to a location behind the knee. Outcomes, though positive on average, vary among individuals, with some patients demonstrating unimproved or worsened knee flexion postoperatively. This variability is due in part to insufficient understanding of the biomechanical causes of stiff-knee gait and the functional effects of surgical treatment. The goal of this dissertation was to clarify the causes of stiff-knee gait and examine the biomechanical mechanism of improvement following rectus femoris transfer surgery. Swing-phase rectus femoris activity is commonly thought to cause of stiff-knee gait, despite evidence that many patients have excessive knee extension moments in preswing rather than swing phase. We compared the effects of preswing to swing phase activity of the rectus femoris on peak knee flexion in swing by creating and analyzing musculoskeletal simulations of subjects with stiff-knee gait. We found that in six out of ten subjects preswing rectus femoris activity had at least a 90% higher effect on peak knee flexion than swing phase rectus femoris activity, suggesting that preswing rectus femoris activity is an important factor limiting knee flexion in some subjects and should be examined to better determine the factors leading to stiff-knee gait. To understand how other muscles, besides rectus femoris, may limit knee flexion in stiff-knee gait, it is first necessary to understand how muscles coordinate successful swing phase knee flexion in unimpaired gait and how muscle contributions change with walking speed, since many stiff-knee subjects walk slowly. We analyzed simulations of unimpaired subjects walking at different speeds to determine the muscles that accelerated and decelerated knee flexion prior to swing. We found that preswing knee flexion acceleration was achieved primarily by the hip flexor muscles with help from biceps femoris short head, suggesting that weakness in these muscles may contribute to stiff-knee gait. Vasti and soleus decelerated knee flexion, suggesting over-activity in these muscles may contribute to stiff-knee gait. We also investigated the mechanism of improvement following rectus femoris transfer surgery. We altered the geometry of rectus femoris and simulated the dynamics of the swing phase of subjects with stiff-knee gait after different surgical procedures. Analysis of the simulations demonstrated that knee flexion may be improved with a reduction of the knee extension moment generated by the rectus femoris, even if the muscle is not converted to a knee flexor. This dissertation clarifies preswing rectus femoris activity as a cause of stiff-knee gait, demonstrates the functional mechanism of improvement following transfer surgery, and informs future research investigating other potential contributors to stiff-knee gait.
  • Digital
    Peter Spector.
    Digital : Wiley2016
    Ion channels -- Action potentials -- Wide complex tachycardia in the emergency room -- Long QT syndrome -- Propagation -- Arrhythmia mechanisms -- Automaticity -- Triggered firing -- Reentry -- Atrial fibrillation : a case study in reentry -- Anatomy for electrophysiologists -- Deducing anatomy -- Electrical activity, electrodes and electrograms -- Electrogram analysis : understanding electrogram morphology -- Differential diagnostic pacing maneuvers -- Electro-anatomic mapping.
  • Digital
    David Bowers, Allan House, David Owens, Bridgette Bewick.
    Digital : ProQuest Ebook Central2014
    Understanding Clinical Papers is a popular and well established introduction to reading clinical papers. It unravels the process of evidence-based practice, using real papers to illustrate how to understand and evaluate published research, and provides clear explanations of important research-related topics.
  • Digital
    editors, Renato D. Lopes, Robert A. Harrington.
    Digital : AccessMedicine2013
    Complete how-to guidance on conducting clinical research, this book addresses the operational challenges of clinical trials and provides a clear explanation of the methodologies necessary to interpret results. The book addresses all aspects of clinical trials, from design and implementation to statistics to regulatory scrutiny. A resource for students, residents, and clinicians who need a working knowledge of clinical research principles. The chapter authors are all leaders in the field and engaged in cutting edge clinical research. Use as a textbook, as a reference, and as a course guide for mandated clinical research training courses.
  • Digital
    edited by Lynn Frewer and Hans van Trijp ; sponsored by MATFORSK.
    Digital : CRCnetBASE2007
    pt. 1. Key influences on consumer food choice -- pt. 2. Product attributes and consumer food choice -- pt. 3. Diversity in consumer food choice: cultural and individual difference -- pt. 4. Consumers, food and health -- pt. 5. Consumer attitude, food policy and practice.
  • Digital
    volume editors, O. Hiort, S.F. Ahmed.
    Digital : Karger2014
    Gonadal development / Lucas-Herald, A.K., Bashamboo, A. -- The masculinization programming window / Welsh, M., Suzuki, H., Yamada, G. -- Androgen action / Werner, R., Holterhus, P.-M. -- Steroid biochemistry / Kamrath, C., Wudy, S.A., Krone, N. -- Next generation sequencing for disorders of sex development / Tobias, E.S., McElreavey, K. -- Advances in neuroimaging / Rodie, M.E., Forbes, K.P., Muir, K. -- Imaging, endoscopy and diagnostic surgery / Wünsch, L., Buchholz, M. -- Fertility issues in the management of patients with disorders of sex development / Guercio, G., Rey, R.A. -- Disorders of sex development peer support / Baratz, A.B., Sharp, M.K., Sandberg, D.E. -- Improving the communication of healthcare professionals with affected children and adolescents / Nordenström, A., Thyen, U. -- Working with adolescents and young adults to support transition / Gleeson, H., Wisniewski, A.B. -- Past experiences of adults with disorders of sex development / GrApSIA, Audí, L. -- Sex hormone replacement in disorders of sex development / Birnbaum, W., Bertelloni, S. -- Hydrocortisone replacement in disorders of sex development / Blankenstein, O. -- Advances in molecular markers of germ cell cancer in patients with disorders of sex development / van der Zwan, Y.H., Cools, M., Looijenga, L.H.J. -- Managing the risk of germ cell tumourigenesis in disorders of sex development patients / Cools, M., Looijenga, L.H.J., Wolffenbuttel, K.P., T'Sjoen, G. -- Timing of hypospadias repair in patients with disorders of sex development / Springer, A., Baskin, L.S. -- Timing of surgery for feminizing genitoplasty in patients suffering from congenital adrenal hyperplasia / Eckoldt-Wolke, F. -- Timing of feminising surgery in disorder of sex development / Wolffenbuttel, K.P., Crouch, N.S. -- Phalloplasty : a panacea for 46,XY disorder of sex development conditions with penile deficiency? / Callens, N.; Hoebeke, P. -- Rare diseases research and practice / Polizzi, A., Balsamo, A., Bal, M.O., Taruscio, D. -- Achieving diagnostic certainty in resource-limited settings / Mazen, I., Raza, J. -- Global application of disorders of sex development-related electronic resources : e-learning, e-consultation and e-information sharing / Muscarella, M., Kranenburg-van Koppen, L., Grijpink-van den Biggelaar, K., Drop, S.L.S. -- International networks for supporting research and clinical care in the field of disorders of sex development / Ahmed, S.F., Bryce, J., Hiort, O.
  • Digital
    Mario Grassi ... [et al.].
    Digital : CRCnetBASE2007
    Mathematical modeling -- Gastrointestinal tract and skin -- Rheology -- Mass transport -- Drug dissolution and partitioning -- Dissolution of crystallites: size effectson on the solubility -- Drug release from matrix systems -- Drug release from microemulsions -- Drug permeation through membranes.
  • Digital
    edited by S. Anders ... [et al.].
    Digital : ScienceDirect2006
  • Digital
    Hasan Yazici, Yusuf Yazici, Emmanuel Lesaffre, editors.
    Digital : Springer2014
    It is imperative that health professionals caring for patients with rheumatic diseases understand how to correctly interpret evidence in their field, taking into account the merits and shortcomings of available data. Understanding Evidence-Based Rheumatology offers a practical assessment of criteria, drugs, trials, and registries and provides useful tools for successfully interpreting this data. The book introduces readers to basic analysis of trial design, statistics, and application of data through no-nonsense, easy-to-follow insights. Using numerous examples, chapters outline the difficulties physicians encounter when measuring disease activity in rheumatology, and offer strategies for systematically approaching these situations. Ethical issues in study design and reporting are examined, and the book closes with a summary of future directions for scientific and clinical studies in rheumatology. Understanding Evidence-Based Rheumatology is an invaluable resource for trainees, experienced clinicians, and scientists, preparing them with the necessary tools to correctly gather evidence and shed light on the difficult practice of rheumatology.
  • Digital
    Manfred Spitznas ; traducción: Hugo Quiroz-Mercado.
    Digital : Springer2006
    Print2006
  • Digital
    edited by William H. Markle, Melanie A. Fisher, Raymond A. Smego, Jr.
    Digital : AccessMedicine2014
    Global health : past, present and future / Amir A. Khaliq and Raymond A. Smego, Jr. -- The global burden of disease / Thuy D. Bui and William H. Markle -- Epidemiology, biostatistics, and surveillance / Christopher Martin -- The health of women/mothers and children / Judy Lewis, Monika Doshi, Deyanira Gonzalez de Leon, and Amany Refaat -- Human trafficking / Clydette Powell -- Environmental health in the global context / Jeffrey K. Griffiths and Edward Winant -- Nutrition / Clydette Powell and John R. Butterly -- Primary care in global health / Jeffrey F. Markuns and Alain J. Montegut -- Malaria / Paul R. Larson and Mark W. Meyer -- Tuberculosis and HIV/AIDS / Lisa V. Adams and Godfrey B. Woelk -- The neglected tropical diseases / Gregory Juckett -- Emerging diseases and antimicrobial resistance / Arif R. Sarwari and Rashida A. Khakoo -- Injury and global health / Jeffry P. McKinzie -- Surgical issues in global health / Eileen S. Natuzzi, et al. -- Humanitarian assistance and disaster relief / Sheri Fink, Vera Sistenich, and Clydette Powell -- Aging populations and chronic illness / Wayne A. Hale, Jane D. Joubert, and Sebastiana Kalula -- Global mental health : the world mental health surveys perspective / Jordi Alonso, Somnath Chatterji, Yanling He, Philip S. Wang, and Ronald C. Kessler -- Global health communications, social marketing, and emerging communication technologies / Gary Snyder -- Economics and global health / Kevin Chan -- Health systems, management, and organization in global health / David Zakus, Onil Bhattacharyya, and Xiaolin Wei -- Global health ethics / Anvar Velji and John H. Bryant -- Education and careers in global health / Jessica Evert and Scott Loeliger.
  • Print
    edited by Mara Buchbinder, Michele Rivkin-Fish, and Rebecca L. Walker.
    Print2016
    Status: Not Checked OutLane Catalog Record
    Health difference, disparity, inequality, or inequity? What difference does it make what we call it? : an approach to conceptualizing and measuring health inequalities and health equity / Paula Braveman -- Global health inequalities and justice / Jennifer Prah Ruger -- Health inequalities and relational egalitarianism / J. Paul Kelleher -- The liberal autonomous subject and the question of health inequalities / Eva Feder Kittay -- Embodied inequalities : an interdisciplinary conversation on oral health disparities / Sarah Horton and Judith C. Barker -- Chasing virtue, enforcing virtue : social justice and conceptions of risk in pregnancy / Debra Debruin, Anne Drapkin Lyerly, Joan Liaschenko, and Mary Faith Marshall -- Justice, respect, and recognition in mental health services : theoretical and testimonial accounts / Paul Brodwin -- Justice, evidence, and interdisciplinary health inequalities research / Nicholas B. King -- Cultural health capital : a sociological intervention into patient-centered care and the Affordable Care Act / Janet K. Shim, Jamie Suki Chang, and Leslie A. Dubbin -- Racial health disparities and questions of evidence : what went wrong with healthy people / Carolyn Moxley Rouse -- Health-care justice, health inequalities, and U.S. health system reform / Carla C. Keirns.
  • Digital
    United States National Library of Medicine, National Institutes of Health ; prepared by Marcia Zorn, Marin P. Allen, Alice M. Horowitz.
    Digital : NLM2004
    Examines some of the barriers that may need to be addressed when designing strategies to connect the audience with appropriate health information materials, services, or resources.
  • Print
    Thomas S. Bodenheimer, Kevin Grumbach.
    Print2009
    Status: Not Checked OutLane Catalog Record
  • Digital
    Thomas Bodenheimer, Kevin Grumbach.
    Digital : AccessMedicine2012
    Introduction: the paradox of excess and deprivation -- Paying for health care -- Access to health care -- Reimbursing health care providers -- How health care is organised--I: primary, secondary, and tertiary care -- How health care is organised--II: health delivery systems -- Health care workforce and the education of health professionals -- Painful versus painless cost control -- Mechanisms for controlling costs -- Quality of health care -- Prevention of illness -- Long-term care -- Medical ethics and rationing of health care -- Health care in four nations -- Health care reform and national health insurance -- Conflict and change in America's health care system -- Conclusion: tensions and challenges -- Questions and discussion topics.
  • Digital
    Thomas Bodenheimer, Kevin Grumbach.
    Digital : AccessMedicine2016
    Introduction: the paradox of excess and deprivation -- Paying for health care -- Access to health care -- Paying health care providers -- How health care is organized-I: Primary, secondary, and tertiary care -- How health care is organized-II: Health delivery systems -- Health care workforce and the education of health professionals -- Painful versus painless cost control -- Mechanisms for controlling costs -- Quality of health care -- Prevention of illness -- Long-term care -- Medical ethics and rationing of health care -- Health care in four nations -- Health care reform and national health insurance -- Conflict and change in America's health care system -- Conclusion: tensions and challenges -- Questions and discussion topics.
  • Digital
    Ann Gee Lisa Ooi.
    Digital2011
    Recent technological advances in high throughput technology, sample preparation and data analysis have made whole genome mRNA and miRNA analysis of purified hematopoietic cell populations much more accessible. The high throughput analysis of the hematopoietic stem cell (HSC) population has yielded massive amounts of data and now we are in the process of biologically validating these targets. Esam1 is one target yielded from microarray analysis of the HSC population. We found Esam1 to be highly and selectively expressed by HSC from mouse bone marrow. Esam1 is also a viable positive HSC marker in fetal, young and aged mice, as well as in mice of several different strains. In addition, we find robust levels of Esam1 transcripts in purified human HSC. Esam1-/- mice do not exhibit severe hematopoietic defects, however, Esam1-/- BM has an increased frequency of HSC and fewer T cells. HSC from Esam1-/- mice give rise to more granulocyte/monocytes in culture and a higher T cell:B cell ratio upon transplantation into congenic mice. These studies identify Esam1 as a novel, widely applicable HSC-selective marker and suggest that Esam1 may play roles in both HSC proliferation and lineage decisions. MicroRNA-125b (miR-125b) is a target yielded from miRNA profiling of the HSC population. We show that miR-125b is highly expressed in HSC and its expression decreases in committed progenitors. Overexpression of miR-125b in mouse HSC enhances their function, demonstrated through serial transplantation of highly purified HSC, and enriches for the previously described Slamf1lo CD34- lymphoid balanced and the Slamf1negCD34- lymphoid biased cell subsets within the multipotent HSC [CD34-KLS] fraction. This enrichment of HSC subsets occur via an anti-apoptotic mechanism, reducing the mRNA expression levels of two pro-apoptotic targets, Bmf and KLF13. The anti-apoptotic effect of miR-125b is more pronounced in the lymphoid biased HSC subset because of their intrinsic higher baseline levels of apoptosis. Together, these data reveal that miR-125b regulates hematopoietic stem cell survival and can promote lymphoid fate decisions at the level of the HSC by preferentially expanding lymphoid balanced and lymphoid biased HSC.

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