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Books

  • Digital
    Phuc Van Pham, editor.
    Contents:
    Intro; Contents; Contributors; Physico-Mechanical Properties of HA/TCP Pellets and Their Three-Dimensional Biological Evaluation In Vitro; 1 Introduction; 2 Materials and Methods; 2.1 Materials; 2.2 Pellet Fabrication; 2.3 Diametral Tensile Strength (DTS) Testing; 2.4 Density Testing; 2.5 Pellet Sterilization; 2.6 Evaluation of Cell Toxicity; 2.7 Cell Attachment Assay; 2.8 Field-Emission Scanning Electron Microscopy with Energy-Dispersive X-Ray Spectroscopy (FESEM-EDX) Analysis for Surface of ...; 2.9 Statistical Analysis; 3 Results; 3.1 Pellet Structure and Morphology 3.2 Cell Toxicity Assay3.3 Osteoblast Proliferation and Attachment Assay; 3.4 FESEM-EDX Analysis of the Pellets ́Surface; 4 Discussion; 5 Conclusion; References; The Robust Potential of Mesenchymal Stem Cell-Loaded Constructs for Hard Tissue Regeneration After Cancer Removal; 1 Introduction; 2 Various Strategies Employed in TE for Hard Tissue Replacement; 2.1 Cell-Free Scaffolds Strategy; 2.2 Bioactive-Loaded Scaffolds Strategy; 2.3 Cell-Based Scaffold Strategy; 3 Requirements of Hard Tissue-Engineered Scaffolds; 3.1 Biocompatibility; 3.2 Biodegradability 3.3 Porosity, Pore Size, and Level of Pore Interconnectivity3.4 Surface Chemistry; 3.5 Mechanical Properties; 3.6 Osteoimmunomodulation; 4 Effective Parameters in the Reciprocal Cell-Scaffold Interaction; 4.1 Cell-Mediated Remodeling of Scaffolds; 4.2 Influence of Scaffold on Cellular Behaviors; 5 Cell-Loading Approaches; 6 Cell-Loaded Constructs in Clinical and Preclinical Settings; 7 Concluding Remarks; References; In Vitro Production of Cartilage Tissue from Rabbit Bone Marrow-Derived Mesenchymal Stem Cells and Polycaprolactone Scaffold; 1 Introduction; 2 Materials-Methods 2.1 Fabrication of Biodegradable Scaffolds2.2 Isolation and Characterization of Rabbit Bone Marrow-Derived Mesenchymal Stem Cells (BMMSCs); 2.3 Production of BMMSCs Expressing Green Fluorescent Protein (GFP-BMMSCs); 2.4 Seeding BMMSCs onto PCL Scaffolds; 2.5 Cell Proliferation Assay; 2.6 In Vitro Cartilage Formation; 2.7 Scanning Electron Microscopy (SEM); 2.8 Gene Expression Evaluation; 2.9 Statistical Analysis; 3 Results; 3.1 Polycaprolactone Scaffold Preparation; 3.2 Successful Isolation of Rabbit Bone Marrow-Derived Mesenchymal Stem Cells; 3.3 BMMSCs Were Successfully Transfected with GFP 3.4 BMMSCs Could Adhere and Proliferate on PCL Scaffolds and Collagen-Coated PCL Scaffolds3.5 BMMSCs Were Differentiated into Chondrocytes in the Scaffold; 4 Discussion; 5 Conclusion; References; Stem Cell Therapy for Tendon Regeneration: Current Status and Future Directions; 1 Introduction; 1.1 Tendon Injuries and Healing; 2 Application of Stem Cells, GFs, and Transcription Factors in Tendon Injury Therapies; 2.1 Stem Cells; 2.1.1 Other Important Cell Sources for Tendon Healing; 2.2 GFs in Tendon Development and Healing; 2.2.1 Effects of Different GFs on Tendon Healing
    Digital Access Springer 2019
  • Digital
    edited by Anwarul Hasan.
    Summary: A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

    Contents:
    Fundamentals. Introduction to Tissue Engineering / Rami Mhanna, Anwarul Hasan
    Biomaterials in Tissue Engineering / Samad Ahadian, Rahaf Rahal, Javier Ramón-Azcón, Raquel Obregón, Anwarul Hasan
    Harnessing the Potential of Stem Cells from Different Sources for Tissue Engineering / Divya Murali, Kunal G Kshirsagar, Anwarul Hasan, Arghya Paul
    Induced Pluripotent Stem Cells in Scaffold-Based Tissue Engineering / Deepti Rana, Minal Thacker, Maria Leena, Murugan Ramalingam
    Biosensors for Optimal Tissue Engineering: Recent Developments and Shaping the Future / Jihane Abouzeid, Ghinwa Darwish, Pierre Karam
    Bioreactors in Tissue Engineering / Raquel Obregón, Javier Ramón-Azcón, Samad Ahadian
    Applications. Tissue-Engineered Human Skin Equivalents and Their Applications in Wound Healing / Lara Yildirimer, Divia Hobson, Zhi Yuan (William) Lin, Wenguo Cui, Xin Zhao
    Articular Cartilage Tissue Engineering / Jiayin Fu, Pengfei He, Dong-An Wang
    Liver Tissue Engineering / Jessica L Sparks
    Development of Tissue-Engineered Blood Vessels / Haiyan Li
    Front Matter
    Engineering Trachea and Larynx / Marta B Evangelista, Sait Ciftci, Peter Milad, Emmanuel Martinod, Agnes Dupret-Bories, Christian Debry, Nihal E Vrana
    Pulmonary Tissue Engineering / Patrick A Link, Rebecca L Heise
    Cardiac Tissue Engineering / Eun Jung Lee, Pamela Hitscherich
    Approaches and Recent Advances in Heart Valve Tissue Engineering / Anna Mallone, Benedikt Weber, Simon P Hoerstrup
    Musculoskeletal Tissue Engineering: Tendon, Ligament, and Skeletal Muscle Replacement and Repair / Jorge A Uquillas, Settimio Pacelli, Shuichiro Kobayashi, Sebastián Uquillas
    Bone Tissue Engineering: State of the Art, Challenges, and Prospects / Jan O Gordeladze, Håvard J Haugen, Ståle P Lyngstadaas, Janne E Reseland
    Tissue Engineering of the Pancreas / Masayuki Shimoda
    Tissue Engineering of Renal Tissue (Kidney) / Raquel Rodrigues-Díez, Valentina Benedetti, Giuseppe Remuzzi, Christodoulos Xinaris
    Design and Engineering of Neural Tissues / Muhammad N Hasan, Umut A Gurkan
    Neural-Tissue Engineering Interventions for Traumatic Brain Injury / Tala El Tal, Rayan El Sibai, Stefania Mondello, Firas Kobeissy
    Bionics in Tissue Engineering / Thanh D Nguyen, Brian P Timko
    Index.
    Digital Access Wiley 2017
  • Digital
    edited by Riitta Seppänen-Kaijansinkko.
    Summary: This book provides a thorough, up-to-date description of the scientific basis and concepts of tissue engineering in the oral and maxillofacial region. The opening chapters present an introduction to tissue engineering, describe the roles of biomaterials and stem cells, discuss the use of growth factors, and examine potential adverse reactions. The challenges of soft and hard tissue engineering for oral and maxillofacial reconstruction are then considered in detail. It is explained what has been achieved to date, and potential future perspectives are explored. The importance and the verification of adequate vascularization are discussed, and a further focus is the use of 3D printing, both in the planning and production of scaffolds and in the bioprinting of cells and biomaterials. Information is also included on safety, efficacy, and regulatory aspects. Tissue Engineering in Oral and Maxillofacial Surgery will be of interest to all researchers and practitioners who wish to learn more about the potential of tissue engineering to revolutionize practice in oral and maxillofacial surgery.

    Contents:
    Introduction to Tissue Engineering
    Biomaterials for cranio-maxillo-facial bone engineering
    Cells
    Physical stimulation in tissue engineering
    Growth factors
    Tissue Engineering of Composite Soft Tissue Grafts for Craniomaxillofacial Reconstruction
    Hard tissue engineering
    Vascularization in Oral and Maxillofacial Tissue Engineering
    3-D Computer Aided Design and Manufacturing
    Safety, Efficacy and Regulation of Mesenchymal Stromal/Stem Cells
    Future perspectives
    with special emphasis on extracellular vesicles.
    Digital Access Springer 2019
  • Digital
    edited by Celeste M. Nelson.
    Contents:
    Probing regional mechanical properties of embryonic tissue using microindentation and optical coherence tomography / Benjamen A. Filas, Gang Xu, and Larry A. Taber
    Hemodynamic flow visualization of early embryonic great vessels using [mu]PIV / Selda Goktas, Chia-Yuan Chen, William J. Kowalski, and Kerem Pekkan
    Using correlative light and electron microscopy to study Zebrafish vascular morphogenesis / Jacky G. Goetz, Fabien Monduc, Yannick Schwab, and Julien Vermot
    Micro/nano-computed tomography technology for quantitative dynamic, multi-scale imaging of morphogenesis / Chelsea L. Gregg, Andrew K. Recknagel, and Jonathan T. Butcher
    Imaging the dorsal-ventral axis of live and fixed Drosophila melanogaster embryos / Sophia N. Carrell and Gregory T. Reeves
    Light sheet-based imaging and analysis of early embryogenesis in the fruit fly / Khaled Khairy [and three others]
    Quantitative image analysis of cell behavior and molecular dynamics during tissue morphogenesis / Chun Yin Bosco Leung and Rodrigo Fernandez-Gonzalez
    A multiplex fluorescent in situ hybridization protocol for clonal analysis of Drosophila oogenesis / Lily S. Cheung and Stanislav Shvartsman
    Active cell and ECM movements during development / Anastasiia Aleksandrova [and three others]
    3D culture assays of murine mammary branching morphogenesis and epithelial invasion / Kim-Vy Nguyen-Ngoc [and five others]
    Culture of mouse embryonic foregut explants / Felicia Chen and Wellington V. Cardoso
    Investigating human vascular tube morphogenesis and maturation using endothelial cell-pericyte co-cultures and a doxycycline- inducible genetic system in 3D extracellular matrices / Stephanie L.K. Bowers [and three others]
    Three-dimensional traction force microscopy of engineered epithelial tissues / Alexandra S. Piotrowski [and three others]
    Probing cell mechanics with subcellular laser dissection of actomyosin networks in the early developing Drosophila embryo / M. Rauzi and P.-F. Lenne
    UV laser ablation to measure cell and tissue-generated forces in the Zebrafish embryo in vivo and ex vivo / Michael Smutny [and four others]
    Measurement of intercellular cohesion by tissue surface tensiometry / Ramsey A. Foty
    Quail-chick chimeras and eye development / Sinu Jasrapuria Agrawal and Peter Y. Lwigale
    Studying epithelial morphogenesis in Dictyostelium / Daniel J. Dickinson, W. James Nelson, and William I. Weis
    Primary cell cultures of regenerating Holothurian tissues / Samir A. Bello, Ricardo J. Abreu-Irizarry, and José́ E. Garcı́a-Arrarás
    Large-scale parameter studies of cell-based models of tissue morphogenesis using CompuCell3D or VirtualLeaf / Margriet M. Palm and Roeland M.H. Merks
    Simulating tissue morphogenesis and signaling / Dagmar Iber [and four others]
    Elasticity-based targeted growth models of morphogenesis / Patrick W. Alford.
    Digital Access Springer 2015
  • Digital
    Joana Vieira Silva, Maria João Freitas, Margarida Fardilha, editors.
    Summary: Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

    Contents:
    Preface
    Tissue-specific cell signaling: introduction
    Beyond the brain signaling
    Cell signaling within pituitary, the master gland of the endocrine system
    Cell signaling within endocrine glands: thyroid, parathyroids and adrenal glands
    Signaling pathways governing activation of innate immune cells
    Cell activation and signaling in lymphocytes
    Signaling pathways involved in kidney and urinary tract physiology and pathology
    More than androgens: hormonal and paracrine signaling in prostate development and homeostasis
    Testicular signaling: team work in sperm production
    Sperm signaling specificity: from sperm maturation until oocyte recognition
    Hormone signaling pathways in the postnatal mammary gland
    Oogenesis signaling: from development to environmental plasticity and aging
    Key signaling pathways in the cardiovascular system
    Growth factor signaling in the maintenance of adult lung homeostasis
    The signaling pathways involved in the regulation of skeletal muscle plasticity
    Adipocyte-specific signaling.
    Digital Access Springer 2020
  • Digital
    edited by Jagadeesh Bayry, INSERM Unité 1138, Paris, France.
    Contents:
    Assaying NF-[kappa]B activation and signaling from TNF receptors
    Dissecting DR3 signaling
    Modulation of fc[epsilon]RI-dependent mast cell response by OX40L
    Analyzing the signaling capabilities of soluble and membrane TWEAK
    Regulation of human dendritic cell functions by natural anti-cd40 antibodies
    [Beta]-actin in the signaling of transmembrane TNF-[alpha]-mediated cytotoxicity
    Investigating the protective role of death receptor 3 (DR3) in renal injury using an organ culture model
    Analysis of TNF-[alpha]-mediated cerebral pericyte remodeling
    CD137 in chronic graft-versus-host disease
    In vitro investigation of the roles of the proinflammatory cytokines tumor necrosis factor-[alpha] and interleukin-1 in murine osteoclastogenesis
    Evasion of TNF-[alpha]-mediated apoptosis by hepatitis C virus
    TNF-[alpha] modulates TLR2-dependent responses during mycobacterial infection
    Experimental applications of TNF-reporter mice with far-red fluorescent label
    A solid-phase assay for studying direct binding of progranulin to TNFR and progranulin antagonism of TNF/TNFR interactions
    Compartment-specific flow cytometry for the analysis of TNF-mediated recruitment and activation of glomerular leukocytes in murine kidneys
    Determination of soluble tumor necrosis factor receptor 2 produced by alternative splicing
    Effective expression and purification of bioactive recombinant soluble LIGHT
    One of the TNF superfamily members: Bifunctional protein, TNFR2-Fc-IL-1ra.
    Digital Access Springer 2014
  • Digital
    David Clark.
    Summary: Palliative medicine was first recognised as a specialist field in 1987. One hundred years earlier, London based doctor William Munk published a treatise on 'easeful death' that mapped out the principles of practical, spiritual, and medical support at the end of life. In the intervening years a major process of development took place which led to innovative services, new approaches to the study and relief of pain and other symptoms, a growing interest in 'holistic' care, and a desire to gain more recognition for care at the end of life. This book traces the history of palliative medicine, from its nineteenth-century origins, to its modern practice around the world. It takes in the changing meaning of 'euthanasia', assesses the role of religious and philanthropic organisations in the creation of homes for the dying, and explores how twentieth-century doctors created a special focus on end of life care. 'To comfort always' traces the rise of clinical studies, academic programmes and international collaborations to promote palliative care. 0It examines the continuing need to support development with evidence, and assesses the dilemmas of unequal access to services and pain relieving drugs, as well as the periodic accusations of creeping medicalization within the field. This is the first history of its kind, and the breadth of information it encompasses makes it an essential resource for those interested in the long-term achievements of palliative medicine as well as the challenges that remain.

    Contents:
    Nineteenth century doctors and care of the dying
    Homes for the terminally ill : 1885-1945
    Interest and disinterest in mid-twentieth century
    Cicely Saunders and her early associates : a kaleidoscope of effects
    Defining the clinical realm
    Specialty recognition and global development
    Palliative medicine : historical record and challenges that remain.
    Digital Access Oxford 2016
  • Digital
    Sarah Cuschieri
    Summary: This book prepares and guides individuals who are about to embark (or already have embarked) on a health/medical PhD journey, with a specific focus on Public Health. Based on the author's experience as a recently graduated Doctor of Philosophy (PhD) student, readers benefit from the knowledge imparted and lessons learned, including an analysis of the different aspects of a Public Health doctoral degree, and practical tips and guidance on how to go about this journey from the initial phase of choosing a research niche up until the oral examination (also called defence). All throughout the book, the author shares examples from her own journey to show that in spite of sacrifices and hurdles along the way, hard work, perseverance, and supportive resources can help see you through, eventually, to a hopefully positive outcome at the end. Using an informal style, the author provides a step-wise guide, from chapter to chapter, on the various essential aspects that need to be considered, including: The initial steps towards a PhD Proposal, permissions and funding The fieldwork The art of data analysis The hurdles along the way - a personal experience What comes after the completion of a PhD? Intended to be a compact go-to guide for students throughout their PhD journey, both from an academic and personal perspective, To Do or Not to Do a PhD? engages readers who are about to enroll in or who already have started a PhD, especially in public health, epidemiology, and health/medical fields of study. The brief also would appeal to postgraduate and undergraduate students who are interested in learning about how to write a research proposal, draft a scientific paper for publication in a journal, or prepare a thesis.

    Contents:
    Intro
    Preface
    Acknowledgements
    Contents
    About the Author
    Chapter 1: What Is a PhD? Am I Ready for This Commitment?
    Why Should I Read for a PhD?
    What Am I Getting Myself into?
    What Types of PhDs Are Out There?
    Chapter 2: The Initial Steps Towards a PhD
    Getting a PhD in the United States
    US Entry Requirements
    Student Visas
    The US PhD Programme
    Getting a PhD in the United Kingdom
    UK Entry Requirements
    The UK PhD Application
    Getting a PhD in Europe
    Entry Requirements
    Chapter 3: Proposal, Permissions and Funding
    The Proposal The Background, Aim and Objectives
    The Study Design (Methodology)
    Expected Outcomes
    Permissions
    Funding
    Funding of the University's Tuition Fees
    Funding for Your Research Project
    Chapter 4: The Fieldwork
    Defining the Population
    Preparation for the Health Survey
    Questionnaire
    Health Examination
    Recruitment of Fieldworkers
    Pilot Study
    Setting Up Your Fieldwork
    Laboratory Fieldwork
    References
    Chapter 5: The Art of Data Analysis
    Parametric or Non-parametric?
    Descriptive Analysis
    Analytic Studies
    Reference Chapter 6: Putting Pen to Paper to Publication
    Structuring a Scientific Paper
    Targeting the Most Appropriate Journal
    References
    Chapter 7: Writing the Thesis
    Thesis vs. Research Manuscripts
    The Structure of a Thesis
    Reference
    Chapter 8: The Hurdles Along the Way: A Personal Experience
    Chapter 9: Getting Ready for the Oral Defence
    Preparing for the Big Day
    Preparing for Your Examiners
    After the Oral Defence
    Chapter 10: What Comes After the Completion of a PhD?
    Academia
    Public and Private Sectors
    Personal Experience
    Index
    Digital Access Springer 2021
  • Digital
    Byron C. Calhoun, Tammi Lewis, editors.
    Contents:
    Introduction: Abuse of Tobacco and Substances
    Physiology of Nicotine
    Physiology of EtOH and Opiate Receptors
    Women's Specific Issues
    Health Effects
    Pregnancy Effects
    Tobacco Cessation
    Addictions Counseling
    Therapeutic Substitution
    Appendix: Protocols and Guidelines.
    Digital Access Springer 2016
  • Digital
    Gonghuan Yang, editor.
    Summary: This book comprehensively covers the science and policy issues relevant to one of the major public health issues in China. It pulls together the prevalence pattern of tobacco use in different population and burden of the myriad of tobacco-related diseases. The book pays more attention to review the successes and failures of tobacco control policies in China, including the protect peoples from second-hand smoke, comprehensive banning tobacco advertisement promotion and sponsor, regulation of the contents of tobacco products and low tar cigarettes, warn about the dangers of tobacco, support for smokers to quit, and increasing tobacco taxation and price, as well as monitor and assessment on tobacco use and implement of prevention policy under the international background of tobacco control. The book analyse and explain the influence factors, especially interference from tobacco industry with public management theory frame for promoting tobacco control policies and looks at lessons learnt to help set health policy for reducing the burden of tobacco-related diseases. It is a helpful reference for experts in public health and epidemiologists in tobacco control, advocators and policy maker.

    Contents:
    Introduction : China and the negotiation of WHO FCTC / Gonghuan Yang
    Tobacco epidemic and health risk in the Chinese population / Gonghuan Yang
    Action subject and surroundings of tobacco control and anti tobacco control in China / Gonghuan Yang
    International assistance and tobacco control in China / Gonghuan Yang
    Tobacco control mass sommunication in China / Chunhui Wang and Jie Yang
    Public interest litigation and tobacco control in China / Jinron Huang
    Monitoring tobacco ese and implementation of tobacco control policies in China / Xia Wan, Jason Hsia, and Gonghuan Yang
    Protecting China from secondhand tobacco smoke / Quan Gan
    Support for smokers to quit / Gonghuan Yang
    Tobacco product regulation and tobacco industry interference / Hanbing Guo
    Health warnings of cigarette package in China / Yiqun Wu and Gonghuan Yang
    Comprehensive ban on tobacco advertising, promotion and sponsorship / Pinpin Zheng, Lin Xiao, Fan Wang, and Gonghuan Yang
    Tobacco tax and tobacco economy in China / Rong Zheng
    Conclusions and recommendations / Gonghuan Yang.
    Digital Access Springer 2018
  • Digital
    volume editors, Robert Loddenkemper, Michael Kreuter.
    Contents:
    History of tobacco production and use / Hanafin, J., Clancy, l.
    Global tobacco epidemic / Mackay, J., Schluger, N.
    The tobacco epidemic and the commercial sector : tobacco industry strategies to increase profits and prevent regulation / Weishaar, H.
    Chemistry and primary toxicity of tobacco and tobacco smoke / Wiebel, F.J.
    Nicotine dependence / Zaveri, N., Rollema, H., Swan, G.E.
    The psychology of the smoker / Gilbert, D.G., Pergadia, M.L.
    Respiratory disorders related to smoking tobacco / Murray, J.F., Buist, A.S.
    Cardiovascular and other (except respiratory) disorders related to smoking tobacco / Barnoya, J., Monzon, J.C.
    Health effects of passive smoking in children / Bush, A.
    Health effects of passive smoking in adults / Kabir, Z., Clancy, L.
    Economics of tobacco use and control / Townsend, J.
    Legislation and smoking prevention / Latif, E., Warner, V.
    The WHO framework convention on tobacco control / Poetschke-Langer, M., Schotte, K., Zilagyi, T.
    Youth and tobacco / Bauer, C., Kreuter, M.
    Impact of media, movies and TV on tobacco use in the youth / Sargent, J.D., Hanewinkel, R.
    Social determinants of cigarette smoking / Upson, D.
    Smoking and mental health problems / Caill-Garnier, S., Baker, A.L, Todd, J., Turner, A., Dayas, C.
    Patterns and predictors of smoking cessation / Ditre, J.W., Zale, E.L., Brandon, T.H.
    Examining the role of the health care professional in controlling the tobacco epidemic : individual, organizational and institutional responsibilities / Leone, F.T., Evers-Casey, S.
    Pharmacotherapy : nicotine replacement therapy and other drugs in smoking cessation (including vaccination) / Tonnesen, P.
    Smokeless tobacco : health hazards or less harm? / Bolinder, G., Gilljam, H. (stockholm)
    Waterpipe tobacco smoking : a less harmful alternative? / Jawad, M.
    Electronic cigarettes : the issues behind the moral quandary / Vardavas, C.I., Agaku, I.T.
    Digital Access Karger 2015
  • Digital
    Nikolai V. Ivanov, Nicolas Sierro, Manuel C. Peitsch, editors.
    Summary: This book describes the history of tobacco genomics, from its "discovery" by Europeans to next-generation omics approaches in plant science. The authors primarily focus on the allotetraploid common tobacco plant (N. tabacum); however, separate chapters are dedicated to closely related Nicotiana species, such as N. benthamiana and N. attenuata, for which substantial progress in omics data analysis has been already achieved. While genetic maps, transcriptomes, and physical maps of BAC libraries have significantly enhanced our understanding of the tobacco plant, the genome of tobacco and related Nicotiana species has opened a new era in modern tobacco research. This book addresses current and future industrial and research applications as well as central challenges in tobacco science, including diseases, low variability of cultivars, the genomes large size, polyploidy, and gene duplication.

    Contents:
    Background and History of Tobacco
    Biodiversity of tobacco
    Genetics of tobacco
    The genome and transcriptome of tobacco and its ancestors
    SGN Tobacco resources and Nicotiana metabolic databases
    Leaf curing: a key step for tobacco chemistry
    Repetitive DNA dynamics and polyploidization in the genus Nicotiana (Solanaceae)
    Interspecific introgression in Nicotiana species
    Nicotine biosynthesis, transpssort, and regulation in tobacco: insights into the evolution of a metabolic pathway.
    Digital Access Springer 2020
  • Digital
    Ming D. Li.
    Summary: This book provides the most recent knowledge on almost all key aspects of the health impact of tobacco smoking. Its 21 chapters focus on both preclinical and clinical studies. The contents are broad, covering the epidemiology of tobacco smoking; genetic epidemiology; identification of susceptibility genomic regions, genes, and pathways as determined by both human and animal studies; evolutionary relations among the different nAChR subunit genes that are so important to the nicotine response; smoking-related diseases; E-cigarettes; and smoking cessation. Furthermore, each chapter includes a detailed and comprehensive list of key references. For both clinical and basic researchers, this book is a valuable resource on nicotine dependence and other addictions.

    Contents:
    The Prevalence of Smoking and Its Associated Diseases
    Addiction Genetics: Basic Concepts and Techniques
    Estimation of Genetic and Environmental Contributions to Smoking Addiction
    Identified Susceptibility Loci for Nicotine Addiction Based on Genome-Wide Linkage Analyses
    Involvement of Variants in Gene Clusters CHRNA5/A3/B4 on Chromosome 15 to Smoking Behaviors and Lung Cancer
    Contribution of Variants in CHRNB3/A6 Gene Cluster on Chromosome 8 to Smoking Dependence
    Genetic Contribution of Variants in GABAergic Signaling to Nicotine Dependence
    Contribution of Variants in DRD2/ANKK1 on Chromosome 11 with Smoking and Other Addictions
    Significant Contribution of Variants in Serotonin Transporter and Receptor Genes to Smoking Dependence
    Converging Findings from Linkage and Association Analyses on Susceptibility Genes for Smoking Addiction
    Contribution of Gene-Gene and Gene-Environmental Interactions to Tobacco Smoking
    Identification of Biological Pathways Associated with Smoking Initiation/Progression, Nicotine Dependence, and Smoking Cessation
    Neuroproteomics and Its Applications in Research on Nicotine and Other Drugs of Abuse
    Regulatory Roles of MicroRNAs in Addictions and Other Psychiatric Diseases
    Tobacco Smoking, Food Intake, and Weight Control
    Nicotine Modulates Innate Immune Pathways via Nicotinic Acetylcholine Receptor
    DNA Methylation Analysis Reveals a Strong Connection between Tobacco Smoking and Cancer Pathogenesis
    Evolutionary Relations of Genes Encoding Nicotinic Acetylcholine Receptor Subunits
    Management, Pharmacotherapies, and Precision Medicine for Smoking Cessation
    Background and Biology of and Health Concerns about Electronic Cigarettes
    Grand Challenges and Opportunities for Psychiatry, Including Nicotine Addiction Research.
    Digital Access Springer 2018
  • Digital
    Vivek H. Murthy, MD.
    Summary: "In Together, the former Surgeon General addresses the overlooked epidemic of loneliness as the underpinning to the current crisis in mental wellness and offers solutions to create connection and stresses the importance of community to counteract the forces driving us to depression and isolation"-- Provided by publisher.

    Contents:
    Section I. Making sense of loneliness
    Under our noses
    The evolution of loneliness
    Cultures of connection
    Why now?
    Unmasking loneliness
    Section II. Building a more connected life
    Relating inside out
    Circling connection
    A family of families.
    Digital Access
    Provider
    Version
    ProQuest Ebook Central
    2020 Limited to 1 simultaneous user
    OverDrive
    2020 Limited to 1 simultaneous usersSUNet ID login required
  • Digital
    Mahmoud F. Sakr.
    Summary: The book offers in a single resource the whole coverage of different diseases and lesions, congenital or acquired, of the tongue, along with a complete spectrum of surgical techniques that can be used to achieve the best functional and aesthetic results. In addition to tongue embryology, surgical anatomy, histology and physiology, the book explores the differential diagnosis of congenital anomalies of the tongue and lingual lesions, as well as the most recent advances in surgical management (resection, reconstruction and surgical management of the neck in patients with tongue cancer). The volume includes unique chapters about tongue replantation and tongue allo-transplantation. Richly illustrated, this book provides an indispensable source of knowledge to all specialists and trainees entrusted with the care of patients suffering from tongue lesions.

    Contents:
    Preface. Embryology of the Tongue. - Surgical Anatomy of the Tongue
    Histology of the Tongue
    Physiology of the Tongue
    Congenital Anomalies
    Tongue Trauma
    Tongue Piercing
    Tongue Discoloration
    Inflammation (Glossitis)
    Tongue Fissures
    Swellings of the Tongue
    Tumors of the tongue
    Ulcers of the Tongue
    Glossectomy
    Reconstruction after Glossectomy
    Surgical Management of the Neck
    Tongue Replantation
    Tongue Transplantation. .
    Digital Access Springer 2022
  • Digital
    volume editors, Alpdogan Kantarci, Leslie Will, Stephen Yen.
    Contents:
    Section 1. Biology and metabolism of alveolar bone
    Section 2. Mechanical properties of dentoalveolar structures
    Section 3. Orthodontic tooth movement
    Section 4. Methods to facilitate orthodontic tooth movement.
    Digital Access Karger 2016
  • Digital
    Andrew Eder, Maurice Faigenblum, editors.
    Summary: This book, now in an extensively revised third edition, is a superbly illustrated and authoritative reference on tooth wear and its management. Tooth wear is becoming an increasing problem as people are living longer and keeping their teeth for longer, with recent UK surveys showing that at least 75% of adults and more than 50% of children now have some form of identifiable tooth wear. This latest edition addresses this growing challenge by describing practical clinical techniques that will aid identification of the aetiological factors responsible for erosion, attrition and abrasion and by offering guidance in the planning and delivery of appropriate patient care. Readers will find helpful information on difficulties encountered in the diagnosis and prevention of tooth wear, problems associated with controlling the process and strategies for providing management solutions. Alongside thorough updates of the original chapters, this new expanded edition includes several entirely new chapters from highly regarded clinicians and researchers from the UK and Europe. This essential clinical guide will meet the needs of dental professionals and dental students alike.

    Contents:
    FM: Foreword
    Tooth wear: Editors introduction
    Part 1: Introduction to tooth wear
    1. An overview of tooth wear
    2. Tooth wear and population oral health
    3. Risk factors in tooth wear
    4. Saliva and tooth wear
    5. Feeding and eating disorders: behaviours that adversely impact oral health
    6. Physiology of erosive tooth wear and relationship with dentine hypersensitivity
    7. Association between tooth wear and dental sleep disorders; an overview
    8. Dento-legal considerations in the management of patients with tooth wear
    Part 2: Management of tooth wear
    9. A pragmatic philosophy of tooth wear management
    10. Treatment planning for patients with tooth wear
    11. Occlusion and splint therapy
    12. Tooth wear in the child and adolescent
    13. Surgical crown lengthening in the management of tooth wear,-14. Orthodontic therapy in the management of tooth wear
    15. Adhesive restorations
    16. Fixed prosthodontics
    17. Removable prosthodontics
    18. Dental implants in the management of tooth wear
    19. Prevention, maintenance and dealing with failures
    BM: Tooth wear: future considerations.
    Digital Access Springer 2022
  • Digital
    Rocky C. Saenz.
    Summary: The highest-yield, most complete gastrointestinal radiology exam prep and learning tool available today! Top 3 Differentials in Gastrointestinal Imaging: A Case Review by renowned radiologist Rocky C. Saenz and esteemed colleagues is one in a series of radiology case books mirroring the highly acclaimed O'Brien classic,Top 3 Differentials in Radiology. The book is organized into five abdominal imaging sections covering hepatobiliary, pancreas and spleen, gastrointestinal (GI) tract, mesentery and vascular, and abdominal wall. Each case is formatted as a two-page unit.

    Contents:
    Part 1. Hepatobiliary
    Part 2. Pancreas and Spleen
    Part 3. Gastrointestinal Tract
    Part 4. Mesentery and Vascular
    Part 5. Abdominal Wall and Soft Tissues.
    Digital Access
    Provider
    Version
    Thieme MedOne Radiology
    Thieme-Connect
  • Digital
    [edited by] Jasjeet Bindra, Robert D. Boutin.
    Summary: "Top 3 Differentials in Musculoskeletal Imaging: A Case Review by Jasjeet Bindra, Robert D. Boutin, and expert contributors is one in a series of radiology case books mirroring the format of the highly acclaimed O'Brien classic, Top 3 Differentials in Radiology: A Case Review. The book is organized in 10 parts: trauma, bone tumors, upper extremity, lower extremity, arthropathies, infection, soft tissue tumors, metabolic musculoskeletal conditions, spine, and pediatric/developmental musculoskeletal conditions"-- Provided by publisher.

    Contents:
    Trauma
    Bone tumors
    Upper extremity
    Lower extremity
    Arthropathy
    Infection
    Soft tissue tumors
    Metabolic musculoskeletal conditions
    Spine
    Pediatric or developmental musculoskeletal conditions.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Radiology
  • Digital
    William T. O'Brien.
    Contents:
    Congenital and developmental
    Attenuation and signal abnormality
    Masses and masslike lesions
    Vasculature and cerebrospinal fluid spaces
    Calvarium and skull base
    Temporal bone
    Sinonasal
    Maxillofacial
    Neck (including spaces)
    Orbits.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Radiology
    Thieme MedOne Neurosurgery
  • Digital
    Ely A. Wolin.
    Contents:
    Neuro
    Thyroid and parathyroid
    Cardiac
    Lung
    Hepatobiliary
    Gastrointestinal
    Genitourinary
    Bone
    Infection and inflammation
    Fluorine-18 Fluorodeoxyglucose Positron-Emission Tomography
    Tumor (not PET)
    Quality control.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Radiology
  • Digital
    Rebecca Stein-Wexler.
    Contents:
    Chest, cardiac, and airway imaging
    Gastrointestinal imaging
    Genitourinary imaging
    Musculoskeletal imaging
    Head and neck imaging
    Brain and spine imaging.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Radiology
  • Digital
    [edited by] William T. O'Brien, Sr.
    Contents:
    Chest and cardiac imaging / John P. Lichtenberger III
    Gastrointestinal imaging / Rocky Saenz
    Genitourinary imaging / Rocky Saenz
    Musculoskeletal imaging / Jasjeet Bindra
    Head and neck imaging / William T. O'Brien, Sr
    Brain and spine imaging / Paul M. Sherman
    Pediatric imaging / Rebecca Stein-Wexler
    Ultrasound imaging / Charles A. Tujo
    Fetal imaging / Erika Rubesova
    Vascular and interventional radiology / David D. Gover
    Nuclear medicine / Ely A. Wolin
    Breast imaging / Robert A. Jesinger
    Roentgen classics / Grant E. Lattin, Jr.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Radiology
  • Digital
    David D. Gover.
    Contents:
    Pre-procedure
    Procedural cases
    Aunt Minnies' because, sometimes, "it is what it is!"
    IR anatomy
    Post-procedure.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Radiology
  • Digital
    Danya Reich, Corinna Eleni Psomadakis, Bobby Buka.
    Digital Access Springer 2017
  • Digital
    Ilya Kister, José Biller
    Summary: "In arriving at a clinical diagnosis, think of the five most common findings (either historical, physical findings, or laboratory) found in a given disorder. If at least three of these five are not present in a given patient, the diagnosis is likely to be wrong. - C. Miller Fisher. Building on this precept from the great 20th-century neurologist C. Miller Fisher, Drs. Ilya Kister and José Biller have identified the five most common findings for the 'top 100' most common and important neurologic syndromes and disorders. The unique format of Top 100 Diagnoses in Neurology includes synopses that tie together the core disease features, illustrations and study questions for each entry, making this book an excellent tool for building a firm knowledge base in neurology and a quick reference for clinicians - neurologists and general practitioners alike. Covers the five core features of 100 of the most important neurologic syndromes and disorders, including polyneuropathies, neurologic vision disorders, movement disorders, epilepsy syndromes, multiple sclerosis, autism spectrum disorder, cerebral palsy, opioid overdose, brain tumors, and much more. Icons are used to identify neurologic emergencies and specify disease prevalence (common, rare, very rare). Includes brief introductions to each section that provide an essential clinical context for each area. Features helpful learning tools for each entry, including illustrations of key concepts, mnemonics, clinical pearls; and carefully chosen study questions to encourage further study and test your knowledge. Each entry contains free online references. Helps you quickly refresh your knowledge of specific disorders and ascertain whether your patients' diagnoses satisfy Fisher's "three-of-five" rule"-- Provided by publisher

    Contents:
    Peripheral Nervous System and the Innervation of the Upper Extremities
    Innervation of the Legs
    Polyneuropathies
    Disorders of the Neuromuscular Junction
    Disorders of the Skeletal Muscle
    Disorders of the Spinal Cord
    Disorders of the Brainstem and Cranial Nerves
    Neurologic Disorders of Vision
    Movement Disorders
    Disorders of Consciousness and Higher Cognitive Functions
    Cerebrovascular Disorders
    Epilepsy
    Nonepileptic Paroxysmal Neurologic Disorders
    Headache Disorders
    Infections of the Central Nervous System
    Immune-Mediated Disorders of the Central Nervous System
    Miscellaneous Section : Neurodevelopmental Disorders, Neurotoxicology, Neurooncology
    Digital Access Ovid 2021
  • Digital
    Alan F. Weissman.
    Summary: Top Score for the Radiology Boards: Q & A for the Core and Certifying Exams is the ideal diagnostic radiology board prep resource. Written by radiologist Alan Weissman, with contributions from dozens of leading experts at renowned institutions, Top Score has a simple ambition: to improve your test scores. The book covers all exam categories, including non-interpretive skills (NIS), physics, safety, breast, cardiac, diagnostic radiology, gastrointestinal, genitourinary, interventional, musculoskeletal, neuroradiology, nuclear, pediatrics, thoracic, ultrasound/reproductive/endocrinology, vascular, and general radiology. Chapters are composed of four types of test cases of varying focus and complexity, each on a two-page spread. Essentials starts with a patient presentation, followed by board-type multiple-choice questions. Details begins with a case presentation, followed by 10 rapid-fire questions, enabling brisk, high-volume learning. Image Rich presents multiple images that require accurate identification, enabling accelerated, high-volume image assessment practice. More Challenging follows the same format as Essentials but adds a higher degree of difficulty. Key highlights High-quality, board-type Q&A with detailed answer explanations High yield "Top Tips" for each case Special radiology artifacts section Image Rich and Details sections aid in rapid and lasting topic mastery Comprehensive review, covering all sections tested by the American Board of Radiology Written by experienced, expert question writers NIS chapter emphasizes proficiency in vital practice-related skills This quintessential home-study guide will help radiology residents and fellows prep for and ace both the certifying and core exams.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Radiology
  • Print
    edited by I. Ronald Shenker.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    RJ550 .T66
    1
  • Digital
    Pramod C. Rath, Ramesh Sharma, S. Prasad, editors.
    Summary: This book presents a collection of articles on various aspects of current research on aging. These include model systems, cellular, biochemical and molecular aspects of experimental aging research, as well as selected intervention studies on age-related diseases. Aging is a global challenge to human society. Children are always in a hurry to become adults, while adults produce offspring and add to the gene pool. However, after adulthood or the attainment of reproductive maturity, all physiological parameters of the living organism start to undergo the aging process. Old age sets in slowly but surely, and usually continues for a prolonged period. If vigor and vitality are the main advantages of adulthood, old age offers the rewards of experience and maturity. Biologists ask questions such as: Why do we age? How do we become old? Is it possible to slow down, postpone or even prevent aging? In turn, medical experts ask: What are the diseases associated with old age? Are there medicines that can help affected elderly patients? In fact both groups are asking themselves how can we add more health to old age. Healthy aging is the dream of every individual. But to achieve this, it is fundamental that we first understand the cellular, biochemical and molecular basis of the aging process in mammalian cells, tissues and intact living organisms, which can serve as experimental model systems in Biomedical Gerontology. Once the biology of aging is understood at the genetic and molecular levels, interventional approaches to aging and its associated diseases may be easier to plan and implement at the preclinical level.
    Digital Access Springer 2017
  • Digital
    Bronner, Felix; Farach-Carson, Mary C.
    Digital Access Springer v. 1-, 2004-
  • Digital
    Renato Anghinah, Wellingson Paiva, Linamara Rizzo Battistella and Robson Amorim, editors.
    Summary: Traumatic brain injury (TBI) refers to nondegenerative, noncongenital damage to the brain from an external mechanical force, which can lead to permanent or temporary impairment of cognitive, physical, and psychosocial functions, with an associated diminished or altered state of consciousness. Despite this broad definition, it is estimated that more than 1.500.000 people suffer TBI annually in US, with 20% afflicted with moderate or severe forms. Additionally, a high percentage of these patients are unable to return to their daily routine (approximately 50%). In this context, both motor and cognitive rehabilitation are extremely important for these individuals. The aim of cognitive and motor rehabilitation is to recover an individual's ability to process, interpret and respond to environmental inputs, as well as to create strategies and procedures to compensate for lost functions that are necessary in familial, social, educational and occupational settings. The purpose of this book is to review the basic concepts related to TBI, including mechanisms of injury, acute and post-acute care, severity levels, the most common findings in mild, moderate and severe TBI survivors, and the most frequent cognitive and motor impairments following TBI, as well as to discuss the strategies used to support post-TBI patients. The most important rehabilitation techniques, both from cognitive and motor perspectives, are addressed. Finally, information regarding work and community re-entry and familial and psychological support are discussed in detail. Topics in Cognitive Rehabilitation in the TBI Post-Hospital Phase is intended as a reference guide for all professionals who have contact with or are related to patients suffering from TBI. Any professionals who work with or are related to patients suffering from TBI will find here a broad and comprehensive overview of TBI, addressing all essential issues, from acute care to rehabilitation strategies, follow up and re-socialization.

    Contents:
    Spontaneous Recovery Mechanisms-Brain Reorganization
    Respiratory Rehabilitation
    Posttraumatic hydrocephalus: Relevance, Mechanisms, Treatment and Outcome
    Challenges and Complications of Immobility
    Motor Rehabilitation Program and Robotics
    Extra-piramidal Syndromes After Traumatic Brain Injury
    Post-Traumatic Epilepsy
    Traumatic Brain Injury and Electroencephalogram Findings
    Mild Traumatic Brain Injury and Post-Concussion Syndrome
    Traumatic Brain Injury in the National Football League
    Traumatic Brain Injury in Fighting Sports
    Neuropsychiatric Symptoms of Post-Concussion Syndrome (PCS) and Chronic Traumatic Encephalopathy (CTE)
    Functional Neuroimage
    Neuropsychological Rehabilitation after Traumatic Brain Injury
    "Come Back to Community and Work after Traumatic Brain Injury".
    Digital Access Springer 2018
  • Digital/Print
    Hohmann, Stefan.
    Print
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    Call number varies. Search for Topics in current genetics to find individual volumes of this title.
  • Digital
    Denise Drozd.
    Summary: Chelicerates do not possess dedicated antennae like the Mandibulata but have evolved their second sets of appendages into the eponymous chelicerae. In scorpions, pectines are specialized comb-like structures, located on the ninth body segment, used for examining the substrate for chemo- and mechanosensory signals. The comb teeth, or pegs, are truncated beveled structures facing the substrate for probing, and are studded with numerous sensory receptors. Afferents from the pectines project into a distinct neuropil of the central nervous system, located behind the fourth walking leg neuropils. Denise Drozd analyzes afferents of single pegs in Mesobuthus eupeus by backfilling, combined with immunohistological labeling of neuropil regions. Her results suggest a topographic representation of the chemosensory fibers within the pectine neuropil instead of the typical chemotopic representation. Contents The Nervous System of Scorpions Structural Analysis of the Posterior Pectine Neuropil Projection Areas of Chemosensory Afferents Target Groups Lecturers and students in the fields of neurobiology, morphology, and zoology The Author Denise Drozd is a PhD candidate of Prof. Dr. Harald Wolf at the Institute of Neurobiology at Ulm University, Germany.

    Contents:
    Intro; Acknowledgement; Contents; Table of Figures; Abstract; 1 Introduction; 1.1 Chemo- and mechanoreception in arthropods; 1.1.1 Chemosensitive structures in arthropods; 1.1.2 Mechanosensitive structures in arthropods; 1.2 Processing of sensory information in the arthropod nervous system; 1.3 Sensory structures in arachnids; 1.4 Mechano- and chemoreceptors in arachnids; 1.4.1 Sensory appendages in scorpions
    the pectines; 1.4.2 The nervous system of scorpions and the pectine neuropil; 1.5 Goal of this thesis; 2 Material and methods; 2.1 Animals
    Mesobuthus eupeus 2.2 Backfill of afferents fibers2.3 Dissection, embedding and sectioning; 2.4 Immunohistochemistry and mounting; 2.5 Microscopy and image analysis; 3 Results; 3.1 Establishment of methods; 3.2 Structural analysis of the posterior pectine neuropil and associated tracts; 3.3 Projection areas of sensory afferents; 4 Discussion; 4.1 Discussion of methods; 4.2 Analysis of the architecture of the posterior pectine neuropil; 4.2.1 The structure of the disc-like area; 4.2.2 The structure of the cap-like area and the large lobulus area; 4.2.3 Somatotopic innervation of the pectine neuropil 5 Conclusion5.1 Outlook; References; Appendix; A 1 Chemicals; A 2 Solutions; A 3 Tools and equipment
    Digital Access Springer 2019
  • Digital
    Walter Siquini, editor ; in collaboration with Raffaella Ridolfo, Pierpaolo Stortoni, Emilio Feliciotti.
    Contents:
    Preface
    1 Position of the patient
    2 Steps shared by Total and Subtotal Gastrectomy
    3 Total Gastrectomy
    4 Manual Subtotal Gastrectomy.- 5 Stapled Subtotal Gastrectomy
    6 Proximal Gastrectomy
    7 Total and Subtotal D2 Laparoscopic Gastrectomy.- 8 Lymphadenectomy
    9 Special Cases.
    Digital Access Springer 2015
  • Digital
    [edited by] David N. Herndon.
    Summary: "Recent advances in research have resulted in tremendous changes in burn management. Stay fully up to date with the new edition of Total Burn Care, by leading authority Dr. David N. Herndon. Detailed procedural guidelines and video clips walk you through every step of the process, from resuscitation through reconstruction and rehabilitation. Everyone on the burn care team, including general and plastic surgeons, intensivists, anesthestists, and nurses, will benefit from this integrated, multidisciplinary guide to safe and effective burn management"--Publisher's description.

    Contents:
    A brief history of acute burn care management
    Teamwork for total burn care : burn centers and multidisciplinary burn teams
    Epidemiological, demographic and outcome characteristics of burns
    Prevention of burn injuries
    Burn management in disasters and humanitarian crises
    Care of outpatient burns
    Prehospital management, transportation, and emergency care
    Pathophysiology of burn shock and burn edema
    Burn resuscitation
    Evaluation of the burn wound : management decisions
    Treatment of infection in burn patients
    Operative wound management
    Anesthesia for burned patients
    The skin bank
    Skin substitutes and 'the next level'
    The pathophysiology of inhalation injury
    Diagnosis and treatment of inhalation injury
    Respiratory care
    The systemic inflammatory response syndrome
    Host defense antibacterial effector cells influenced by massive burns
    Biomarkers in burn patient care
    Hematology, hemostasis, thromboprophylaxis, and transfusion medicine in burn patients
    Significance of the hormonal, adrenal, and sympathetic responses to burn injury
    The hepatic response to thermal injury
    Importance of mineral and bone metabolism after burn
    Micronutrient homeostasis
    Hypophosphatemia
    Nutritional needs and support for the burned patient
    Modulation of the hypermetabolic response after burn injury
    Etiology and prevention of multisystem organ failure
    Acute renal failure in association with thermal injury
    Critical care in the severely burned : organ support and management of complications
    Burn nursing
    Care of the burned pregnant patient
    Special considerations of age : the pediatric burned patient
    Care of geriatric patients
    Surgical management of complications of burn injury
    Electrical injuries
    Cold-induced injury : frostbite
    Chemical burns
    Radiation injuries and vesicant burns
    Exfoliative diseases of the integument and soft tissue necrotizing infections
    Burn injuries of the eye
    The burn problem : a pathologist's perspective
    Molecular and cellular basis of hypertrophic scarring
    Pathophysiology of the burn scar
    Burn rehabilitation along the continuum of care
    Musculoskeletal changes secondary to thermal burns
    Reconstruction of bodily deformities in burn patients : an overview
    Reconstruction of the head and neck after burns
    Management of postburn alopecia
    Trunk deformity reconstruction
    Management of contractural deformities involving the shoulder (axilla), elbow, hip, and knee joints in burned patients
    Acute and reconstructive care of the burned hand
    Management of burn injuries of the perineum
    Reconstruction of burn deformities of the lower extremity
    Electrical injury : reconstructive problems
    The role of alternative wound substitutes in major burn wounds and burn scar resurfacing
    Aesthetic reconstruction in burn patients
    Laser for burn scar treatment
    The ethical dimension of burn care
    Intentional burn injuries
    Functional sequelae and disability assessment
    Management of pain and other discomforts in burned patients
    Psychiatric disorders associated with burn injury
    Psychosocial recovery and reintegration of patients with burn injuries
    Digital Access ClinicalKey 2018
  • Digital
    Alfredo Hoyos
    Summary: "Total Definer: An Atlas of Advanced Body Sculpting by internationally-renowned aesthetic plastic surgeon Alfredo Hoyos is a visually stunning atlas that presents groundbreaking and advanced surgical, fat grafting, liposuction, and body sculpting techniques. Readers will learn how to perform High Definition (HD) and Dynamic Definition (HD2) Liposculptures."-- Provided by publisher

    Contents:
    Artnatomy
    Basics
    Safety
    Corporal Photography
    Patient-Centered Care
    Surgery General Aspects
    Chest
    Abdomen
    Posterior Torso
    Arms
    Gluteal Region
    Lower Limb
    Excisional Body Sculpting
    Secondary Procedures
    Technologies for HD
    Masterpieces
  • Digital
    Kalliopi Lampropoulou-Adamidou, George Hartofilakidis.
    Contents:
    1. Late close reduction in patients with CHD
    2. Previous osteotomies
    3. High dislocations with no previous treatment.
    4. Pre-operative evaluation of CHD with 3D CT scan
    5. Idiopathic osteoarthritis
    6. Inflammatory arthritis
    7. Avascular necrosis
    8. Re-cementing revisions
    9. Completed cases
    10. Miscellaneous
    11. Key messages and lessons learned
    12. Relative publications.
    Digital Access Springer 2017
  • Digital
    E. Carlos Rodríguez-Merchán, Sam Oussedik, editors.
    Summary: This book offers a comprehensive guide to total knee arthroplasty (TKA) that will assist in achieving excellent outcomes based on a sound understanding and technique. After an introductory section on the native knee that covers the anatomy, physiology, biomechanics, and patterns of disease, all aspects of primary knee arthroplasty are discussed in detail. Individual chapters are devoted to topics such as acute pain management, the role of technological aids, prosthetic kinematics, alignment targets, unicompartmental arthroplasty, patellar resurfacing, outcome measures, and cost-effectiveness. An extensive section explains the causes and management of potential complications, including aseptic failure, infections, and periprosthetic fracture. The surgical techniques appropriate for revision knee arthroplasty are described separately, and guidelines on how to deal with bone loss, instability, and extensor mechanism failure are provided. The authors are all respected experts from the United Kingdom, United States, Australia and Europe.
    Digital Access Springer 2015
  • Digital
    Richard D. Scott.
    Summary: "An invaluable guide for orthopaedic surgeons at all levels of experience, Total Knee Arthroplasty, 3rd Edition, takes a practical, authoritative approach to this widely performed procedure. Dr. Richard Scott, co-designer of the Total Knee System, walks you step by step through a wide range of surgical scenarios, offering consistent, readable coverage of the techniques you need to know. A user-friendly index, hundreds of detailed, full-color illustrations and photographs, and bulleted summaries make information easy to find and put to use in practice."
    Digital Access ClinicalKey 2019
  • Digital
    Theofilos Karachalios, editor.
    Contents:
    1. A brief history of total knee arthroplasty
    2. Kinematics of the natural and replaced knee
    3. Long term survival of total knee arthroplasty. Lessons learned from the clinical outcome of old designs
    4. Long term survival of total knee arthroplasty. Lessons learned from the clinical outcome of old designs. Second generation of implants and the total condylar TKA
    5. Total knee arthroplasty. Evaluating outcomes
    6. The long term outcome of total knee arthroplasty. The effect of age and diagnosis
    7. Long term outcome of primary total knee arthroplasty. The effect of body weight and level of activity
    8. Long term clinical outcome of total knee arthroplasty. The effect of the severity of deformity
    9. Long term clinical outcome of total knee arthroplasty. The effect of surgeon training and experience
    10. Long term clinical outcome of total knee arthroplasty. The effect of limp alignment, implant placement and stability as controlled by surgical technique
    11. Long term results of total knee arthroplasty. The effect of surgical approach
    12. Long term clinical outcome of total knee arthroplasty. The effect of posterior stabilized designs
    13. Long term clinical outcome of total knee arthroplasty. The effect posterior cruciate retaining design
    14. Rationale and long term outcome to rotating platform total knee replacement
    15. Mid to long term clinical outcome of medial pivot designs
    16. Long term clinical outcome of total knee arthroplasty. The effect of implant fixation (cementless)
    17. Long term clinical outcome of total knee arthroplasty: the effect of polyethylene
    18. Long term clinical outcome of total knee arthroplasty. Condylar constrained prostheses
    19. Long term clinical outcome of total knee arthroplasty rotating hinge designs
    20. Clinical outcome of total knee megaprosthesis replacement for bone tumors
    21. Long term clinical outcome of total knee arthroplasty. The effect of patella resurfacing
    22. Infected total knee arthroplasty. Basic science, mangement, and outcome
    23. Short and mid term outcome of total knee arthroplasty. The effect of rahabilitation
    24. Mid and long term functional outcome of total knee arthroplasty
    25. Long term outcome of total knee arthroplasty. The effect of navigation
    26. Quality of life and patient satisfaction after total knee arthroplasty using contemporary designs
    Index.
    Digital Access Springer 2015
  • Digital
    [edited by] Anthony P. Sclafani.
    Summary: "Otolaryngology-Head and Neck Surgery has developed as a specialty in recognition of the highly focused attention necessary to fully comprehend and master the intricate anatomic and physiologic relationships of the structures located between the thoracic inlet and the foramen magnum. Our specialty originally developed out of a need to manage the intricacies of this area of the body, but as the depth of our knowledge grew subspecialties within the discipline branched off, and often it may seem that we are a collection of otologists, neurotologists, head and neck oncologists, laryngologists, pediatric otolaryngologists, rhinologists, facial plastic surgeons, and general otolaryngologists. This text should serve as a concise yet practical review and reference textbook for anyone interested in the full scope of otolaryngology-head and neck surgery"--Provided by publisher.
  • Digital
    Mark Lazenby.
    Summary: Nurses are positioned on healthcare's front line, intimately connected to individuals, families, and communities. How can they leverage this position to work for the common good? In Toward ward a Better World, Mark Lazenby, a philosopher and a nurse, presents a plan of action. He argues that nurses advance the good society when they fulfill fundamental obligations. Promoting equality, peace and respect, providing assistance and safety, and safeguarding the health of our planet are among these obligations. By acting upon them, nurses become a force for social change in their communities. But through the collective power of more than 20 million nurses worldwide, nurses become a global force for making the world a better place--in the present and for the future.

    Contents:
    Nursing and the Good Society ; Part I: Nursing is a Moral Profession
    Nursing and Our Common Humanity
    Nursing and Obligation ; Part II: The Obligations of Nursing
    Equality
    Assistance
    Peace
    Safety
    Respect ; Part II: Nursing Beyond Boundaries
    Nursing is Always Local
    The Social Significance of Nursing.
    Digital Access Ovid 2020
  • Digital
    Travis N. Rieder.
    Summary: This thought-provoking treatise argues that current human fertility rates are fueling a public health crisis that is at once local and global. Its analysis and data summarize the ecological costs of having children, presenting ethical dilemmas for prospective parents in an era of competition for scarce resources, huge disparities of wealth and poverty, and unsustainable practices putting irreparable stress on the planet. Questions of individual responsibility and integrity as well as personal moral and procreative issues are examined carefully against larger and more long-range concerns. The author's assertion that even modest efforts toward reducing global fertility rates would help curb carbon emissions, slow rising global temperatures, and forestall large-scale climate disaster is well reasoned and more than plausible. Among the topics covered: · The multiplier effect: food, water, energy, and climate. · The role of population in mitigating climate change. · The carbon legacy of procreation. · Obligations to our possible children. · Rights, what is right, and the right to do wrong. · The moral burden to have small families. Toward a Small Family Ethic sounds a clarion call for bioethics students and working bioethicists. This brief, thought-rich volume steers readers toward challenges that need to be met, and consequences that will need to be addressed if they are not.

    Contents:
    Global Population Crisis
    The Collective Action Problem
    Duties to Possible Children
    Duty Not to (Contribute to) Harm
    Duties of Justice
    Duties of Rescue
    Demandingness, Integrity and Morality
    Duty and Intimacy
    Conclusion.
    Digital Access Springer 2016
  • Digital
    O.S. Miettinen.
    Summary: Scientific medicine in Miettinen's conception of it is very different from the two ideas about it that came to eminence in the 20th century. To him, medicine is scientific to the extent that it has a rational theoretical framework and a knowledge-base from medical science. He delineates the nature of that theoretical framework and of the research to develop the requisite knowledge for application in such a framework. The knowledge ultimately needed is about diagnostic, etiognostic, and prognostic probabilities, and it necessarily is to be codified in the form of probability functions, embedded in practice-guiding expert systems.

    Contents:
    The daunting needs for knowledge
    The necessary forms of the knowledge
    The knowledge according to its source
    Needed innovations of the knowledge culture
    Original research for scientific diagnosis
    Original research for scientific etiognosis
    Original research for scientific prognosis
    Derivative research for scientific gnosis
    From gnostic research to gnostic knowledge.
    Digital Access Springer 2014
  • Digital
    Martine Derzelle.
    Summary: A rigorous and groundbreaking study. Martine Derzelle is the first researcher to approach hypochondria as a relational pathology. Martine Derzelle is the first researcher to approach hypochondria as a relational pathology. The author tackles a subject that has puzzled care professionals for decades: hypochondria. Martine Derzelle confronts all specialists (psychotherapists, psychiatrists, doctors, psychosomaticians) with the paradox of this pathology and the theoretical void on which the approach to those patients who express a suffering of various kinds has stood for more than a century. In the first part, the author highlights the lack of theoretical elaboration on hypochondria in the existent literature; in the second part, on the basis of clinical examples, she analyzes the nature of the disease, and then offers a completely innovative theoretical elaboration. Finally, in the third part, she proposes a new and specific approach to treating this pathology at both the theoretical and clinical levels within the framework of psychoanalysis and implementing key concepts from relational psychosomatics.

    Contents:
    Questions
    Problems
    Problem Definition
    Negative Reports or 'a Certain Discourse Used in a Certain Way'
    From Biological Body to Metaphorical Body
    A New Starting Point
    Hypochondria, Projective Parenthesis
    A Different Relation to Oneself and to the Other Person
    Towards a Psychosomatic Conception of Hypochondria.
    Digital Access Springer 2014
  • Digital
    Sirpa Sarlio.
    Summary: This clear-sighted volume synthesizes wide-ranging knowledge of human food consumption, food production systems, and sustainability to offer methods of improving the impact of food choices on people and the environment. The comprehensive coverage addresses myriad challenges and paradoxes (e.g., health-conscious food choices that put greater stress on the planet, hunger amidst plenty) associated with the production of sustainable, nutritious food. Direct and complex links between local and global issues are highlighted in innovative approaches to transforming food production from the farm to the table and from the policy desk to the real world. Chapters identify, examine, and offer realistic recommendations for achieving critical goals, among them: Supporting healthy people and communities within planetary boundaries Reduction and prevention of food waste Combining health and sustainability on the plate "Serving sustainable and healthy food to consumers and decision makers": from commitment to action. Investing in healthier and more sustainable production. Ensuring a healthy sustainable diet is a goal of all public policies. Towards Healthy and Sustainable Diets is geared toward professionals and policymakers dealing with food, nutrition, and environmental topics seeking new perspectives on longstanding issues in these interrelated areas. It also makes a suitable reference for students studying and conducting research in these areas.
    Digital Access Springer 2018
  • Digital
    Sanjeev Kelkar, Shubhangi Muley, Prakash Ambardekar.
    Digital Access Springer 2019
  • Digital
    Cheryl Dellasega.
    Summary: Nursing has a not-so-secret problem. The profession is prone to--some would say thrives on--workplace conflict, incivility, bullying, and meanness. And while nurses observe and experience this conflict daily, too few have been trained in its resolution. Toxic Nursing aims to change that with strategies, tools, and techniques to help nurse leaders, managers, and administrators defuse conflict, turn around toxic situations, and create positive, healthy work environments. Written by Cheryl Dellasega--author of the groundbreaking books Surviving Ophelia and Mean Girls Grown Up--Toxic Nursing explores the reasons behind toxic behavior and its impact on not just the workplace but patient safety.

    Contents:
    Incivility
    The newbie : mistreatment of new nurses
    The know-it-all/criticism queen
    Gossip and trash talk
    Cliques, campaigns, and high-school drama
    Competition and credit
    Nurse managers as the problem
    Men in white
    Better than you
    Generations at work
    Competent and caring leaders?
    Social media, electronic communication, and professionalism
    Politics and CYA
    Patients as victims
    On the battlefield : nurses under attack
    Toxic culture/environment
    Conclusion
    Is your management style causing conflict?
    Conflict case scenario
    Organizational cynicism self-assessment
    When it's time to seek outside counsel
    Compassion fatigue.
    Digital Access R2Library 2021
    Limited to 1 simultaneous user
  • Digital
    Jean L. Wright, editor.
    Summary: This book is a comprehensive guide to breast toxicity. Adjuvant radiation remains standard for a majority of women who undergo breast-conserving surgery for breast cancer, and indications for post-mastectomy and regional lymph node irradiation have also broadened with recent publications. At the same time, locoregional recurrence has declined and survival has improved in recent decades. In the current era of excellent breast cancer outcomes, then, considering the balance between toxicity and outcomes becomes paramount. Several recent editorials recommend considering toxicity against the potential benefit of adjuvant radiation in tailoring radiation decisions for individual patients. Thus, a clear understanding of the potential toxicities of adjuvant radiation for breast cancer is critical to optimizing outcomes in modern breast cancer management. Here, authors have collected recent data focused on toxicity of treatment that provide an opportunity for improving this optimization. Chapters cover both acute and late toxicity of radiation for breast cancer, including tailored risk assessment for each of these potential toxicities, considerations for including risk of toxicity in management decisions, and toxicity management strategies. This is an ideal guide for radiation oncologists, residents, and oncologists seeking to optimize care for their patients. .
    Digital Access Springer 2019
  • Digital
    José M. Fuentes, editor.
    Summary: Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.

    Contents:
    Regulation of Autophagy In Health And Disease
    Role of Chaperone-Mediated Autophagy in Ageing and Neurodegeneration
    Interaction Between Mitochondria And Autophagy
    Dual role of autophagy in neurodegenerative diseases: The case of amyotrophic lateral sclerosis
    Autophagy pathways in Huntington?s disease
    Control of Autophagy in Parkinson's Disease
    Autophagy in Alzheimer's disease: a cleaning service out-of-order?
    Autophagy as a neuroprotective mechanism against 3-nitropropionic acid-induced cell death
    Paraquat: Molecular Mechanisms of Neurotoxicity and its Relation with Autophagy
    Agrochemicals-induced Dopaminergic Neurotoxicity: Role of Mitochondria-mediated oxidative stress and Protein Clearance Mechanisms
    Molecular And Neurochemical Mechanisms Dopamine Oxidation To O-Quinones In Parkinson ́S Disease Pathogenesis
    Exploring the Role of Autophagy in the Pathogenesis of Rotenone-Induced Toxicity.- Autophagic pathology and calcium deregulation in neurodegeneration. .
    Digital Access Springer 2015
  • Digital/Print
    Contents:
    Acetone
    Acrolein
    Acrylamide
    Acrylonitrile
    Aldrin/Dieldrin
    Aluminum
    Americium
    Ammonia
    Aniline
    Antimony
    Arsenic
    Asbestos
    Atrazine
    1,3-Butadiene
    2,3-Benzofuran
    2-Butanone
    2-Butoxyethanol
    Barium
    Benzene
    Benzidine
    Beryllium
    Bis(2-chloroethyl) Ether
    Bis(chloromethyl) Ether
    Blister Agents HN-1HN-2HN-3 Nitrogen Mustards
    Blister Agents: Lewisite (L), Mustard-Lewisite Mixture (HL)
    Blister Agents: Sulfur Mustard Agent H/HD, Sulfur Mustard Agent HT
    Boron
    Bromodichloromethane
    Bromoform & Dibromochloromethane
    Bromomethane
    1-Bromopropane
    Cadmium
    Calcium Hypochlorite/Sodium Hypochlorite
    Carbon Disulfide
    Carbonyl Sulfide
    Carbon Monoxide
    Carbon Tetrachloride
    Cesium
    Chlordane
    Chlorfenvinphos
    Chlorinated Dibenzo-p-dioxins (CDDs)
    Chlorine
    Chlorine Dioxide & Chlorite
    Chlorobenzene
    Chlorodibenzofurans (CDFs)
    Chloroethane
    Chloroform
    Chloromethane
    Chlorophenols
    Chlorpyrifos
    Chromium
    Cobalt
    Copper
    Creosote
    Cresols
    Crotonaldehyde
    Cyanide
    1,1-Dichloroethane
    1,1-Dichloroethene
    1,2 Dibromoethane
    1,2-Dibromo-3-Chloropropane
    1,2-Dichloroethane
    1,2-Dichloroethene
    2,4-Dichlorophenoxyacetic Acid
    1,2-Dichloropropane
    1,2-Diphenylhydrazine
    1,3 Dichloropropenes
    1,3 Dinitrobenzene & 1,3,5 Trinitrobenzene
    1,4-Dioxane
    2,4- & 2,6-Dinitrotoluene
    Dinitrotoluenes --3,3'-Dichlorobenzidine
    DDT, DDE, DDD
    DEET (N,N-diethyl-meta-toluamide)
    Di(2-ethylhexyl)phthalate (DEHP)
    Di-n-butyl Phthalate
    Di-n-octylphthalate (DNOP)
    Diazinon
    Diborane
    Dichlorobenzenes
    Dichlorvos
    Diethyl phthalate
    Diisopropyl Methylphosphonate (DIMP)
    Dinitrocresols
    Dinitrophenols
    Disulfoton
    Endosulfan
    Endrin
    Endrin/Endrin aldehyde
    Ethion
    Ethylbenzene
    Ethylene Dibromide
    Ethylene Glycol and Propylene Glycol
    Ethylene Oxide
    Fluorine, Hydrogen Fluoride, and Fluorides
    Formaldehyde
    Fuel Oils / Kerosene
    Gasoline, Automotive
    Glutaraldehyde
    Glyphosate
    Guthion
    2-Hexanone
    Heptachlor/Heptachlor Epoxide
    Hexachlorobenzene
    Hexachlorobutadiene
    Hexachlorocyclohexane (HCH)
    Hexachlorocyclopentadiene (HCCPD)
    Hexachloroethane
    Hexamethylene Diisocyanate (HDI)
    HMX (Octogen)
    Hydraulic Fluids
    Hydrazines
    Hydrogen Chloride
    Hydrogen Cyanide (HCN)
    Hydrogen Fluoride (HF)
    Hydrogen Peroxide
    Hydrogen Sulfide
    n-Hexane
    Iodine
    Ionizing Radiation
    Isophorone
    Jet Fuels JP-4 and JP-7
    Jet Fuels JP-5 and JP-8
    Jet Fuels (JP5/8/JetA)
    Lead
    4,4'-Methylenebis(2-Chloroaniline)(MBOCA)
    4,4'-Methylenedianiline
    Malathion
    Manganese
    Mercury
    Methoxychlor
    Methyl Isocyanate
    Methyl Mercaptan
    Methyl Parathion
    Methyl tert-Butyl Ether (MTBE)
    Methylene Chloride
    Methylenediphenyl Diisocyanate
    Mirex & Chlordecone
    n-Nitrosodi-n-propylamine
    n-Nitrosodimethylamine
    n-Nitrosodiphenylamine
    Naphthalene, 1-Methylnapthalene, 2-Methylnapthalen
    Molybdenum
    Nerve Agents (GA, GB, GD, VX)
    Nickel
    Nitrate and Nitrite
    Nitrobenzene
    Nitrogen Oxides
    Nitrophenols
    Otto Fuel II and its Components
    Parathion
    Pentachlorophenol
    Perchlorates
    Perfluoroalkyls
    Phenol
    Phosgene
    Phosgene Oxime
    Phosphate Ester Flame Retardants
    Phosphine
    Plutonium
    Polybrominated Biphenyls (PBBs)
    Polybrominated Diphenyl Ethers (PBDEs)
    Polychlorinated Biphenyls (PCBs)
    Polycyclic Aromatic Hydrocarbons (PAHs)
    Propylene Glycol
    Pyrethrins-and-Pyrethroids
    Pyridine
    Radium
    Radon
    RDX (Cyclonite)
    Selenium
    Selenium Hexafluoride
    Silica
    Silver
    Sodium Hydroxide
    S,S,S-Tributyl Phosphorotrithioate (Tribufos)
    Stoddard Solvent
    Strontium
    Styrene
    Sulfur Dioxide
    Sulfur Mustard
    Sulfur Trioxide & Sulfuric Acid
    Synthetic Vitreous Fibers
    1,1,1-Trichloroethane
    1,1,2,2-Tetrachloroethane
    1,1,2-Trichloroethane
    1,2,3 Trichloropropane
    1,3,5 Trinitrobenzene & 1,3 Dinitrobenzene
    2,4,6-Trinitrotoluene (TNT)
    Tetrachloroethylene (PERC)
    Tetryl
    Thallium
    Thorium
    Tin and Compounds
    Titanium Tetrachloride
    Toluene
    Toluene Diisocyanate
    Total Petroleum Hydrocarbons (TPH)
    Toxaphene
    Trichlorobenzenes
    Trichloroethylene (TCE)
    Tungsten
    Unidentified Chemical
    Uranium and Compounds
    Used Mineral-based Crankcase Oil
    Vanadium and Compounds
    Vinyl Acetate
    Vinyl Chloride
    White Phosphorus
    Xylenes
    Zinc.
    Digital Access ATSDR 2001-
    Access via ATSDR - Toxic substances portal
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    Call number varies. Search for Toxicological profile to find individual volumes of this title.
  • Print
    Irving Sunshine, section editor.
    Print Access Request
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    Retired Reference (Downstairs)
    RB37 .C182
    1
  • Digital
    edited by Philip Wexler.
    Summary: Toxicology in the Middle Ages and Renaissance provides an authoritative and fascinating exploration into the use of toxins and poisons in the Middle Ages and Renaissance. Part of the History of Toxicology and Environmental Health series, this volume is a follow-up, chronologically, to the first two volumes which explored toxicology in antiquity. The book approximately covers the 1100s through the 1600s, delving into different aspects of toxicology, such as the contributions of scientific scholars of the time, sensational poisoners and poisoning cases, as well as myths. Historical figures, such as the Borgias and Catherine de Medici are discussed. Toxicologists, students, medical researchers, and those interested in the history of science will find insightful and relevant material in this volume. Provides the historical background for understanding modern toxicologyIllustrates the ways previous civilizations learned to distinguish safe from hazardous substances, how to avoid them, and how to use them against enemies. Explores the way famous historical figures used toxins.
    Digital Access ScienceDirect 2017
  • Digital
    edited by Louis M. Weiss and Kami Kim.
    Summary: This book reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism.

    Contents:
    1. The history and life cycle of Toxoplasma gondii / J.P. Dubey
    2. The ultrastructure of Toxoplasma gondii / David J.P. Ferguson, Jean-Francois Dubremetz
    3. Molecular epidemiology and population structure of Toxoplasma gondii / Marie-Laure Darde, Daniel Ajzenberg, Chunlei Su
    4. Human Toxoplasma infection / Rima McLeod [and three others]
    5. Ocular disease due to Toxoplasma gondii / Emily Su, Andrea Honda, Paul Latkany
    6. Toxoplasmosis in wild and domestic animals / David S. Lindsay, J.P. Dubey
    7. Toxoplasma animal models and therapeutics / Carsten G.K. Luder, Utz Reichard, Uwe Gross
    8. Biochemistry and metabolism of Toxoplasma gondii : carbohydrates, lipids and nucleotides / Isabelle Coppens, Takashi Asai, Stanislas Tomavo
    9. The apicoplast and mitochondrion of Toxoplasma gondii / Frank Seeber, Jean E. Feagin, Marilyn Parsons
    10. Calcium storage and homeostasis in Toxoplasma gondii / Silvia N.J. Moreno, Lucas Borges Pereira, Douglas A. Pace
    11. The Toxoplasma gondii parasitophorous vacuole membrane : a multifunctional organelle in the infected cell / Anthony P. Sinai
    12. Toxoplasma secretory proteins and their roles in cell invasion and intracellular survival / Maryse Lebrun, Vern B. Carruthers, Marie-France Cesbron-Delauw
    13. The Toxoplasma cytoskeleton : structures, proteins and processes / Naomi Morrissette, Marc-Jan Gubbels
    14. Interactions between Toxoplasma effectors and host immune responses / Barbara A. Butcher [and three others]
    15. Bradyzoite development / Laura J. Knoll, Tadakimi Tomita, Louis M. Weiss
    16. Development and application of classical genetics in Toxoplasma gondii / James W. Ajioka, L. David Sibley
    17. Genetic manipulation of Toxoplasma gondii / Damien Jacot [and four others]
    18. Epigenetic and genetic factors that regulate gene expression in Toxoplasma gondii / William J. Sullivan, Jr. [and three others]
    19. ToxoDB : an integrated functional genomic resource for Toxoplasma and other sarcocystidae / Omar S. Harb, David S. Roos on behalf of the Eupathdb Group
    20. Comparative aspects of nucleotide and amino acid metabolism in Toxoplasma gondii and other apicomplexa / Kshitiz Chaudhary, Barbara A. Fox, David J. Bzik
    21. Toxoplasma gondii chemical biology / Matthew Bogyo, Gary Ward
    22. Proteomics of Toxoplasma gondii / Jonathan M. Wastling, Dong Xia
    23. Cerebral toxoplasmosis : pathogenesis, host resistance and behavioural consequences / Yasuhiro Suzuki [and five others]
    24. Innate immunity to Toxoplasma gondii / Dana G. Mordue, Christopher A. Hunter
    25. Adaptive immunity and genetics of the host immune response / Craig W. Roberts [and five others]
    26. Vaccination against toxoplasmosis : current status and future prospects / Craig W. Roberts [and three others].
    Digital Access ScienceDirect 2014
  • Print
    [Letizia Vaccari, recopiladora].
    Contents:
    Tomo I. 1904-1914
    Tomo II. 1915-1923
    Tomo III. 1923-1930
    Tomo IV. 1931-1936
    Tomo V. 1937-1946
    Tomo VII. 1954-1957
    Tomo VIII. 1960-1965
    Tomo IX. 1965-1967.
    Print Access Request
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    Books: History - LC Classification (Downstairs)
    R481.V4 T7
    8
  • Digital
    edited by Jerome O. Nriagu and Eric P. Skaar.
    Contents:
    Introduction / Jerome O. Nriagu and Eric P. Skaar
    Is metal uptake related to ecological niche in the vertebrate host? / Joseph Lemire, Trevor F. Moraes, Vahis Fa Andisi, and Anthony B. Schryvers
    Competition for metals among microbes and their host / Michaell A. Bachman and Jeffrey N. Weiser
    The fate of intracellular metal ions in microbes / Slade A. Loutet, Anson C.K. Chan, Marek J. Kobylarz, Meghan M. Verstraete, Stephanie Pfaffen, Bin Ye, Angel L. Arrieta, and Michael E.P. Murphy
    Common mechanisms of bacterial metal homeostasis / James A. Imlay
    Intervention strategies for metal deficiency and overload / Fudi Wang and Lihong Zhang
    Trace metals in host-microbe interactions : the microbe perspective / Jennifer S. Cavet, Robert D. Perry, Sascha Brunke, K. Heran Darwin, Carol A. Fierke, James A. Imlay, Michael E.P. Murphy, Anthony B. Schryvers, Dennis J. Thiele, and Jeffrey N. Weiser
    Metal homeostasis during development, maturation, and aging : impact on infectious diseases / Inga Wessels
    Impact of metals on immune response and tolerance, and modulation of metal metabolism during infection / Günter Weiss
    Metal-based antiparasitic therapeutics / Maribel Navarro and Gonzalo Visbal
    Impact of lifestyle on metal exposure, homeostasis, and associated diseases / George V. Dedoussis
    Obesity, trace metals, and infection / Jerome O. Nriagu
    Metals in host-microbe interaction : the host perspective / Dieter Rehder, Robert E. Black, Julia Bornhorst, Rodney R. Dietert, Victor J. DiRita, Maribel Navarro, Robert D. Perry, Lothar Rink, Eric P. Skaar, Miguel C.P. Soares, Dennis J. Thiele, Fudi Wang, Günter Weiss, and Inga Wessels
    Selenium and mercury : their interactions and roles in living organisms / Tamara Garcia-Barrera
    New technologies using trace metals of concern / Jozef M. Pacyna, Kyrre Sundseth, and Elisabeth G. Pacyna
    The promise of nanometals : reducing infection and increasing biocompatibility / Mian Wang, Wenwen Liu, and Thomas J. Webster
    Metals in the environment as risk factors for infectious diseases : gaps and opportunities / M. Leigh Ackland, Julia Bornhorst, George V. Dedoussis, Rodney R. Dietert, Jerome O. Nriagu, Jozef M. Pacyna, and John M. Pettifor
    Emerging strategies in metalloproteomics / Peter-Leon Hagedoorn
    Measuring metals in complex biological systems / Andreas Matusch, Ana-Maria Oros-Peusquens, and J. Sabine Becker
    Methods and technologies for studying metals in biological systems / Wolfgang Maret, Joseph A. Caruso, Christopher H. Contag, David P. Giedroc, Peter-Leon Hagedoorn, Andreas Matusch, Eric P. Skaar, and Richard B. Thompson.
    Digital Access eBook Comp Acad 2015
  • Print
    Hemphill, Delbert D.
    Print Access Request
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    Books: General Collection (Downstairs)
    RA565.A1 T75
    8
  • Digital
    Terence Pires de Farias, editor.
    Digital Access Springer 2018
  • Digital
    Eckart Klemm, Andreas Nowak, editors.
    Summary: This book provides a practical guide to the complications encountered in tracheotomy procedures. Chapters cover the entire treatment journey, from indication and performance of all types of tracheotomies to the occlusion of the stoma. A tracheotomy can often have serious complications and the management and prevention of these complications are discussed in detail. Practical anatomy, anesthesia for airway management, and surgical and endoscopic treatment of diseases related to tracheotomies are also covered. This book is aimed at a multidisciplinary audience and is relevant to ENT specialists, head and neck surgeons, chest surgeons, anesthesiologists, intensivists, emergency doctors, oral and maxillofacial surgeons, pediatric surgeons, pediatric intensivists, pulmonologists, speech therapists, respiratory therapists, and nurses.

    Contents:
    1. Tracheotomy when and where?
    2. Advantages and disadvantages of tracheotomy, contraindications of percutaneous dilatation tracheostomies
    3. Anatomy and topography in relation to tracheostomy
    4. Histomorphology of Tracheal Barriers of Tracheotomy Patients
    5. Methods of percutaneous dilated tracheostomy
    6. Methods of surgical tracheostomy
    7. The pediatric tracheostomy
    8. The coniotomy, a life-saving emergency measure
    9. Tracheostomy closure: execution, errors, dangers and complications
    10. Complications of the tracheostomy and strategies to prevent it
    11. Iatrogenic tracheal injuries
    therapeutic options
    12. Surgical treatment of laryngotracheal stenosis
    13. Endoluminal splinting of the trachea
    14. Tracheostomy in patients with increased intracranial pressure
    15. Jet ventilation in the difficult airway
    16. Anesthetic and respiratory medical specialties in percutaneous dilatative trachacheostomies
    17. The way to the deanery
    18. Special aspects of skin and mucous membrane care after tracheostomies
    19. Tracheostomy tubes and cannula care
    20. History of tracheostomy.
    Digital Access Springer 2020
  • Digital/Print
    edited by Jane L. Stevens Crawshaw, Irena Benyovsky Latin, Kathleen Vongsathorn.
    Summary: Tracing Hospital Boundaries' explores, for the first time, how the forces of both integration and segregation shaped hospitals and their communities between the eleventh and twentieth centuries in Europe, North America and Africa. Within this broad comparative context it also shines a light on a number of case studies from Southeastern Europe. The eleven chapters show how people's access to, and experience of, healthcare institutions was affected by social, cultural and economic, as well as medical, dynamics. These same factors intersected with developing healthcare technologies to shape hospital design and location, as well as internal policies and practices. The volume produces a new history of the hospital in which boundaries - both physical and symbolic - are frequently contested and redrawn.
    Digital Access 2020
  • Digital/Print
    Summary: This report is the first of its kind to measure health service coverage and financial protection to assess countries' progress towards universal health coverage. It shows that at least 400 million people do not have access to one or more essential health services and 6% of people in low- and middle-income countries are tipped into or pushed further into extreme poverty because of health spending.--Publisher description.

    Contents:
    Preface
    Contributors
    Abbreviations
    Glossary
    Executive summary
    Chapter 1. Bringing UHC into focus
    Defining UHC
    Tracking UHC
    The main UHC monitoring challenges
    Conclusion
    References
    Chapter 2. Coverage of health interventions
    Global health service coverage indicators
    Towards a list of comprehensive UHC tracer indicators
    Conclusion
    Chapter 3. Monitoring financial protection
    OOP in the broader funding context
    National measures of financial protection
    Ensuring the poor are not left behind
    Positive trends in financial protection
    Going forward
    References
    Chapter 4. Looking back, moving forward
    Looking back
    Moving forward
    References
    Annex 1. Coverage indicators
    Annex 2. Financial protection indicators.
    Digital Access WHO 2015
    Print Access Request
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    Books: General Collection (Downstairs)
    RA412 .B647 2015
    1
  • Digital
    edited by Yves C. Vanlandewijck, Walter R. Thompson.
    Contents:
    Introduction to the paralympic movement / Walter R. Thompson
    Biomechanics and ergonomics / Helco van Keeken, Sonja de Groot, Riemer Vegter, Lucas van der Woude
    Physiology / Claudio Perret, Thomas Abel
    Paralympic sports medicine / Cheri A. Blauwet, Jan Lexell, Wayne Derman
    The psychology of paralympians and mental preparation / Jeffrey J. Martin
    Sociology of sport and coaching / P. David Howe
    Research needs for the development of evidence-based systems of classification for physical, vision, and intellectual impairments / Sean M. Tweedy, David Mann, Yves C. Vanlandewijck
    Sport and technology / Osnat Fliess-Douer, Barry Mason, Larry Katz, Chi-hung Raymond So
    Contribution of sport science to performance : wheelchair rugby / Yves C. Vanlandewijck
    Contribution of sports science to performance : swimming / Brendan Burkett
    Contribution of sport science to performance : Nordic skiing / Vesa Linnamo, Walter Rapp, Stefan J. Lindinger.
    Digital Access Wiley 2017
  • Digital
    Nader Francis, Abe Fingerhut, Roberto Bergamaschi, Roger Motson, editors.
    Contents:
    1. Learning environment and setting up a training unit in Minimal Access Surgery
    2. Training curriculum in Minimal Access Surgery
    3. Simulation and Training in Minimal Access Surgery
    4. Training basic laparoscopic skills
    5. Training for trainers in Endoscopy (colonoscopy)
    6. Teaching advanced laparoscopic skills in colorectal surgery
    7. Teaching advanced laparoscopic skills in surgery for morbid obesity
    8. Teaching advanced laparoscopic skills in urological surgery
    9. Training for new thechniques and robotic surgery in Minimal Access Surgery
    10. Teletraining in Minimal Access Surgery
    11. Assessment and Acreditation in Minimal Access Surgery
    12. Training the trainer in laparoscopic surgery
    13. The Human Factor in Minimal Access Surgical Training: How conscientious, well trained Surgeons make mistakes.
    Digital Access Springer 2015
  • Print
    par L. Testut, professeur d'anatomie à la Faculté de Médecine de Lyon ; avec la collaboration pour l'histologie et l'embryologie de mm. G. Ferré, professeur agrégé à la Faculté de Médecine de Bordeaux, et L. Vialleton, chef des travaux histologiques à la Faculté de Médecine de Lyon.
    Contents:
    t. 1. Ostéologie. Arthrologie. Myologie
    t. 2. Angéilogie. Système nerveux central
    t. 3. Système nerveux périphérique. Organes des sens
    t. 4. Appareil de la digestion. Appareil de la respiration et de la phonation. Appareil uro-génital. Embryologie.
    Print
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  • Digital/Print
    Tillaux, P.
    Digital Access
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    Google Books
    Google Books
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    Stored offsite. Please request print.
    E531 .T57 1879
    2
  • Digital/Print
    par MM. J. Babinski, Gilbert Ballet, P. Blocq, E. Boix, H. Dutil, H. Grenet, Hallion, H. Lamy, Ch. Laubry, H. Meige, Rogues de Fursac, A. Souques ; avec figures dans le texte.
    Digital Access Google Books [1899]-
    Print Access Request
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    L41 .T76 1905
    1
  • Digital/Print
    Grasset, J.; Rimbaud, Louis.
    Contents:
    [t.] 1. Fonctions de réception, absorption, circulation, elaboration et élimination de la matière: trophobiologie (Deuxième édition revue et autmentée par le docteur Rimbaud. 1915. [8], 1,059 p. incl. XXXIII tables, 1 diagr.)
    2. Fonctions de défense contre la maladie: antixénisme (1911. [6], 1,010 p. 2 fold. tables)
    3. Fonctions de réception, élaboration et émission de l'énergie, neurobiologie: fonctions de reproduction: ontogénie et phylogénie, hérédité (1912. [6], 1,176 p. incl. 37 ill, XXXII tables).
    Digital Access
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    J113 .G76
    3
  • Print
    publié sous la direction du J. Senèque, par J.P. Binet ... [et al.].
    Print Access Request
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    M32 .S47
    2
  • Digital/Print
    Gérard, Ernest.
    Digital Access Google Books 1903-
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    J53 .G35 1907
    1
  • Digital/Print
    par F. Viault [et] F. Jolyet.
    Digital Access Google Books 1889-
    Print Access Request
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    Stored offsite. Please request print.
    F34 .V62 1894
    1
  • Digital/Print
    Clerc, F.-F.
    Digital Access Google Books 1866-
    Print Access Request
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    N32 .C62 1866
    1
  • Digital/Print
    Rédigées, et précédées de l'anatomie et de la physiologie de la peau par E. Gaucher.
    Contents:
    Contents
    t. 1, fasc. 1. Anatomie et physiologie. Pathologie générale. fasc. 2. Dermatoses inflammatoires communes.
    Digital Access Google Books 1881-
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    T71 .H64
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  • Digital/Print
    par R. Leriche.
    Contents:
    t.
    1. Fractures articulaires.
    Digital Access Google Books 1917-
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    M156 .L61
    1
  • Print
    stef m. shuster.
    Summary: "Stef shuster traces the development of trans medicine since the 1950s to modern medicine to show how providers create and use scientific and medical evidence to "treat" a gender identity. But, why do medical providers have authority over gender? And, what might the consequences of how providers make decisions in trans medicine teach us about medicine in general? Using historical documents, interviews with physicians and therapists, and observations of health conferences, Trans Medicine offers a rare opportunity to understand how providers make decisions given widespread uncertainty while facing challenges to their expertise. In the process of negotiating these challenges in the "treatment" of gender, providers have acquired authority not only in this medical area, but over gender itself"-- Provided by publisher. Emerging in the mid-twentieth century, yet shrouded in social stigma, transgender medicine is now a rapidly growing medical field. In Trans Medicine, stef m. shuster explores its development and how it is being used to "treat" gender identity today. From genital reconstructions to hormone injections, shuster shows that the practice of trans medicine charts new medical ground, often compelling medical professionals to plan treatments without large-scale clinical trials to back them up. Relying on cultural norms and gut instincts to inform their treatment plans, shuster shows how medical providers' lack of clinical experience and scientific research can undermine their ability to interact with patients, craft treatment plans, and make medical decisions. As providers navigate the developing knowledge surrounding the medical care of trans folk, Trans Medicine offers a rare opportunity to understand how providers make decisions, and how they ultimately acquired authority not only over clinical outcomes, but over gender itself--back cover.

    Contents:
    Introduction
    Part I. Historical contexts of trans medicine, 1950s-1970s : 1. Creating worthy patients, 1950-1970
    2. Legitimacy wars between physicians and therapists
    Part II. Contemporary trans medicine : 3. Making it up: evidence in contemporary trans medicine
    4. Medical uncertainty: working with trans patients
    5. Uncertain expertise in trans medicine
    Conclusion: Rethinking the treatment of gender.
    Print Access Request
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    RA564.9.T73 .S48 2021
    1
  • Digital
    Sam Atallah, editor.
    Summary: This book captures cornerstone developments in a new body of knowledge and provides an expert resource on a "hot topic" in rectal surgery. Transanal minimally invasive surgery (TAMIS) was designed for local excision of select rectal neoplasms, however soon it became realized that the TAMIS technique could be used for applications beyond local excision, most notably for transanal total mesorectal excision (taTME). This new operative technique has revolutionized our approach to the distal rectum by allowing for improved access, especially in obese male patients with an android pelvis, and by minimizing abdominal wall access trauma. The endpoints of improved oncologic resection, as defined by mesorectal envelope completeness, negative circumferential resection margins, and negative distal margin, are assessed. This book details controversies, pitfalls, and future directions of taTME and TAMIS. Chapters are authored by those on the forefront of innovation with TAMIS and taTME, and each is considered an authority on the topic. Transanal Minimally Invasive Surgery (TAMIS) and Transanal Total Mesorectal Excision (taTME) is a must-have reference for surgeons who are performing this operation and fellows in training who want to completely understand the various nuances of TAMIS and taTME.

    Contents:
    Historical Perspectives and Rationale for Development
    TAMIS: Indications and Contraindications
    An Algorithm for Local Excision for Early Stage Rectal Cancer
    Complete Clinical Response in Rectal Cancer after Neoadjuvant Therapy-Organ-Preservation Strategies and the Role of Surgery
    Salvage Surgery after TAMIS Excision of Early Stage Rectal Cancer
    Organ Preservation and Palliative Options for Rectal Cancer
    Operative Equipment and Insufflator Options
    Operating Theater Setup and Perioperative Considerations
    Surgical Technique for Local Excision of Rectal Neoplasia
    Pyramidal Excision for Early Rectal Cancer and Special Closure Techniques
    Closure versus Non-Closure after Excision
    Operative and Peri-Operative Outcomes
    Functional Outcomes after Local Excision of Rectal Neoplasia
    Oncologic Outcomes for Local Excision of Rectal Neoplasia
    Applications Beyond Local Excision
    The Evolution of Robotic TAMIS
    Transanal Robotic Surgery and Future Directions
    TAMIS: Current Controversies and Challenges
    Indications for Malignant Neoplasia of the Rectum
    Indications for Benign Disease of the Rectum
    Operating Theatre Setup & Two-Team Coordination
    Single-Team taTME
    Transanal Access Platform Options & Instrument Innovations
    Intra-Operative Decision Making: Converting to taTME, When and for Whom?
    Key Aspects of the Abdominal Dissection
    Zen and the Art of the Pursestring
    An Overview of Operative Steps and Surgical Technique
    Strategies for Ultra Low-Lying Rectal Cancer
    Critical Anatomical Landmarks in Transanal Total Mesorectal Excision (taTME)
    Urethral Injury: The New Challenge for taTME
    How to Avoid Urethral Injury in Males
    A Roadmap to the Pelvic Autonomic Nerves During Transanal Dissection
    Operative Vectors, Anatomic distortion, and the Inherent Effect of CO2 Dissection
    Total Hindgut Mesenteric Mobilization for taTME
    The Role for Perfusion Angiography
    Perioperative Preparation and Post-Operative Care Considerations
    Intra-Operative Morbidity TaTME
    Functional Outcomes to Transanal Minimally Invasive Surgery (TAMIS) and Transanal Total Mesorectal Excision (taTME)
    Oncologic Outcomes
    TaTME for Radical Exenteration
    taTME for Abdominoperineal Resection
    Hartmann's Reversal by a Combined Transanal-Transabdominal Approach
    Pure NOTES Transanal taTME
    Totally Robotic taTME
    Experiences and Challenges to Date
    Next Generation Robots for taTME
    Video-Based Training Apps and Deferred Live Surgery
    Navigation for Transanal Total Mesorectal Excision
    Current Controversies and Challenges
    Transanal Total Mesorectal Excision: The Next Ten Years.
    Digital Access Springer 2019
  • Digital
    edited by Moustafa Kardjadj, Adama Diallo, Renaud Lancelot.
    Summary: This book primarily focuses on the African Sahel region, shedding new light on the epidemiology, socio-economics, clinical manifestations and control approaches of transboundary animal diseases (TADs) in this specific region. In addition to the description of TADs in Sahelian Africa and connected regions, several issues regarding the burden of TADs, the role of national/regional/international veterinary organizations in the surveillance process, animal mobility, one health and TADs in the dromedary are discussed. The book contains 22 chapters and is structured in three parts, i- general features and commonalities, ii- viral diseases, iii- bacterial diseases. Each chapter was written by a group of experts specialized in the topic. This work will be of general interest to researchers, veterinarians, veterinary public health officers, and students engaged in the surveillance and control of animal infectious diseases, included those of zoonotic nature and that are prevalent in the Sahel.

    Contents:
    Part 1
    General features and commonalities
    Chapter 01 : The Sahelian region: characteristics and challenges (Moustafa Kardjadj, Algeria)
    Chapter 02: The burden of transboundary animal diseases (Jonathan Rushton, Bruce Mieghan, UK)
    Chapter 03 : TADs and global changes (Matthew Baylis, UK)
    Chapter 04 : TADs and animal mobility (Mark Rweyemamu, South Africa)
    Chapter 05 : TADs surveillance and control (including national vet services, regional approach, regional and international organizations, GF-TADs) (Karim Tounkara, Mali)
    Chapter 06 : One Health
    Opportunities and challenges (Esther Schelling, Switzerland; Mahamat Fayiz Abakar, Chad)
    Chapter 07 : TADs in dromedary (Bernard Faye, France)
    Part 2
    Viral diseases
    Chapter 08 : Rabies (Jakob Zinsstag, Monique Lechenne, Switzerland)
    Chapter 09 : Rift Valley fever and vectors of RVFV (Renaud Lancelot, France)
    Chapter 10: Other mosquito-borne diseases (WNF ...) (Assane Gueye Fall, Senegal)
    Chapter 11: Ebola and other haemorrhagic fevers (Matthieu Bourgarel, France)
    Chapter 12: Foot-and-mouth disease (Tesfaalem T. Sebhatu, USA)
    Chapter 13: Peste des petits ruminants (Adama Diallo, France)
    Chapter 14: Lumpy skin disease and vectors of LSDV (Esayas Gelaye, Ethiopia)
    Chapter 15: Sheep and goat pox (Khalil Zro, Morocco)
    Chapter 16: African horse sickness and vectors of AHSV (Javier Castillo-Olivares, Spain)
    Chapter 17: Bluetongue and vectors of BTV (Alessio Lorusso, Italy)
    Chapter 18: African swine fever (Emmanuel Couacy-Hyman, Cote Divoire)
    Chapter 19: Avian influenza (Clement Meseko, Nigeria)
    Chapter 20: Newcastle disease (Giovani Cattoli, Italy)
    Part 3
    Bacterial diseases
    Chapter 21: Brucellosis (Jacques Godfroid, Norway)
    Chapter 22: Tuberculosis (Lilian Akudo Okeke, Nigeria)
    Chapter 23: Contagious bovine pleuropneumonia (William Amanfu, Ghana)
    Chapter 24: Contagious caprine pleuropneumonia (François Thiaucourt, Lucia Manso Silvan, France)
    Chapter 25: Heartwater and Amblyomma variegatum (Hassane Adakal, Niger).
    Digital Access Springer 2019
  • Digital
    by Jacques Ganoulis, Jean Fried.
    Summary: Attending water security is an important challenge and a major systemic risk humanity faces in the years to come. This is due to population increase, over-consumption of water, especially in agriculture, climate change and various forms of water pollution. The issue becomes more complicated in transboundary water catchments that cover almost half of the world's land surface, with about 60% of global river flow and 40% of the world's population. Also, in many parts of the planet, like Saharan Africa, population depends on groundwater resources located in transboundary aquifer systems. These facts illustrate the importance of the book's subject, which is the governance of transboundary waters, both surface and groundwater. The book is written by two distinguished scientists, who, having worked in various international institutions, like UNESCO, GEF, UNEP and at the European Commission, have both an extended expertise on how to bridge the gap between science and political decision-making, which is the main factor for an effective governance of water resources. What is new in the book is the integrated analysis of transboundary governance of both surface water and groundwater, as it occurs in reality. In current literature, groundwater is still often missing for the benefit of surface water or, on the contrary, it is treated separately from surface water. The most important feature of the book is to distinguish between the real and a "good" or an effective transboundary water governance and to provide practical tools, methodologies and examples for its implementation in the field. Published timely during 2018, the book will contribute to address successfully practical problems of governance of transboundary waters that represent a very important part of our precious fresh water resources.

    Contents:
    Part 1 Main Aspects of Transboundary Waters
    Chapter 1 Hydrology of internationally shared rivers and lakes
    Chapter 2 Hydrogeological characteristics of transboundary aquifers
    Chapter 3: Potential water conflicts and cooperation across political borders
    Part 2 Definition and Needs of an Effective Transboundary Water Governance
    Chapter 4 Water governance definitions and recent challenges
    Chapter 5 Transboundary water governance: analytical framework
    Chapter 6 Integrating technical, legal and institutional instruments
    Part 3 Transboundary Water Governance in Practice
    Chapter 7 Assessment and communication of benefits for promoting international cooperation
    Chapter 8 Global, regional and local legal and regulatory instruments: case studies
    Chapter 9 The role of international joint institutions: examples of application
    Part 4 Developing a Shared Vision
    Chapter 10 Negotiation, conflict resolution, communication and public participation
    Conclusion.
    Digital Access Springer 2018
  • Digital
    editor Venerino Poletti.
    Summary: This book presents both theoretical and practical aspects of transbronchial cryobiopsy, a new diagnostic technique for the detection of diffuse parenchymal lung disease that is attracting great interest in the scientific community. In the context of a multidisciplinary discussion, comprising radiologic-pathologic correlations, the authors examine the technical and safety issues – such as equipment, endoscopic setting, anesthesiologic approaches and bleeding control – on one hand, and the diagnostic yield and clinical meaning on the other. The volume offers several case studies – including idiopathic pulmonary fibrosis, granulomatous disorders, interstitial pneumonias, rare lung disseminated tumors– that illustrate the high diagnostic yield and safety of this innovative technique. The book appeals to a wide readership, including residents, pulmonologists with expertise in diffuse parenchymal lung diseases, interventional pulmonologists, thoracic radiologists, pathologists, anesthesiologists, internists and rheumatologists.
    Digital Access Springer 2019
  • Digital
    edited by Catherine M. Otto, Bernard D Prendergast, Simon Redwood.
    Digital Access ClinicalKey 2023
  • Digital
    Arturo Giordano, Giuseppe Biondi-Zoccai, Giacomo Frati, editors.
    Summary: This book provides comprehensive information on transcatheter aortic valve implantation (TAVI), which was introduced for the treatment of aortic valve disease less than two decades ago. It explains how TAVI has delivered satisfactory results even in high and intermediate risk patients and outlines how it continues to evolve, thus requiring awareness of state of the art approaches to indication, risk stratification, device choice, procedure, and follow-up. In addition, it reports on the complex and multidisciplinary approach needed to maximize the efficacy, safety, and appropriateness of TAVI, providing detailed clinical, interventional and surgical perspectives focusing on the development of this cardiovascular intervention. Starting with the history of TAVI, addressing the interventional anatomy of aortic valve disease, and reporting on the expert authors' day-to-day experiences, this highly informative book offers an essential update for all cardiologists and surgeons interested in transcatheter aortic valve implantation, as well as any clinician, decision-maker and stakeholder involved in patient selection, procedural management, and follow-up.

    Contents:
    I
    Pathophysiological and translational perspectives
    1 History of transcatheter aortic valve implantation
    2 Interventional anatomy of aortic valve disease
    3 Pathophysiology of aortic
    4 Pathophysiology of aortic regurigation
    5 Pathophysiology of degenerated bioprosthesis
    6 Role of inflammation in native and prosthetic aortic valve disease
    7 Predictive computational models of transcatheter aortic valve implantation
    8 Hemodynamic issues with transcatheter aortic valve implantation
    9 Risk scores for aortic valve
    II Clinical perspectives
    10 Role of rest and stress echocardiography in transcatheter aortic valve implantation
    11 Role of computed tomography in transcatheter aortic valve implantation
    12 Role of magnetic resonance imaging in transcatheter aortic valve implantation
    13 Concomitant coronary artery disease and aortic stenosis
    14 Comparison of transcatheter aortic valve implantation to medical therapy in prohibitive risk patients
    15 Clinical and imaging follow-up after transcatheter aortic valve implantation
    16 Biomarkers before, during and after transcatheter aortic valve implantation
    17 Prognostic impact of aortic regurgitation and paravalvular leak
    18 Leaflet motion abnormalities
    19 Gender-related differences in transcatheter aortic valve implantation
    20 Implementation issues for transcatheter aortic valve implantation: cost-effectiveness, wait-times and volume-outcome balance
    III Interventional perspectives
    21 Transfemoral access management for transcatheter aortic valve implantation
    22 Challenging anathomy for transcatheter aortic valve implantation
    23 Abbott Vascular program for transcatheter aortic valve implantation
    24 Boston Scientific program for transcatheter aortic valve implantation
    25 Edwards program for transcatheter aortic valve implantation
    26 JenaValve program for transcatheter aortic valve implantation
    27 Medtronic program for transcatheter aortic valve implantation
    28 Self-expanding vs balloon-expandable devices for transcatheter aortic valve implantation
    29 Individualized device choice for transcatheter aortic valve implantation
    30 Predilation for transcatheter aortic valve implantation
    31 Postdilation for transcatheter aortic valve implantation
    32 Embolic protection devices for transcatheter aortic valve implantation
    33 Antithrombotic therapy during and after transcatheter aortic valve implantation
    34 Contrast induced nephropathy and transcatheter aortic valve implantation
    35 Conduction disorders and permanent pacemaker requirement after transcatheter aortic valve implantation
    36 Systolic dysfunction and hemodynamic support in patients candidate for transcatheter aortic valve implantation
    37 Radiation exposure in transcatheter aortic valve implantation
    38 Procedure efficiency in transcatheter aortic valve implantation
    39 Predictors of success for transcatheter aortic valve implantation
    40 Learning curve, procedural volumes and relationship with clinical outcomes for transcatheter aortic valve implantation
    41 Aortic valvuloplasty as bridge vs destination therapy
    IV Surgical perspectives
    42 Role of the heart team in decision making for transcatheter aortic valve implantation
    43 Alternative accesses for transcatheter aortic valve implantation
    44 Comparison of transcatheter aortic valve implantation to surgery in intermediate risk patients
    45 New approaches for aortic valve disease: from transcatheter aortic valve implantation to sutureless aortic valves
    46 Hybrid procedures for aortic valve disease: transapical aortic valve implantation through lower left anterior mini-thoracotomy vs Edwards Intuity valve implantation through upper right anterior mini-thoracotomy
    V Future perspectives
    47 Medical treatment for aortic valve disease
    48 Transcatheter aortic valve implantation for pure aortic regurgitation
    49 New-generation devices for transcatheter aortic valve implantation
    50 Bioresorbable valve for transcatheter aortic valve implantation: tomorrow's world from preclinical to clinical
    51 Focus on transcatheter aortic valve implantation in low risk patients
    52 Conclusion.
    Digital Access Springer 2019
  • Digital
    A. Claire Watkins, Anuj Gupta, Bartley P. Griffith.
    Summary: This concise manual describes in detail how to perform a transcatheter aortic valve replacement (TAVR) procedure and provides cardiac surgeons and cardiologists with the foundation necessary to begin practicing TAVR. It includes background on the landmark data establishing the field of TAVR, instructions in the pre- and post-operative management of TAVR patients, and technical descriptions of the newest and most common devices and how to use them. Written by leaders in the field, it offers an unbiased, academic review and describes the experience of colleagues who have learned through trial and error. The Transcatheter Aortic Valve Replacement Manual is an essential resource for physicians and related professionals, residents, fellows, and graduate students in cardiology, cardiac surgery, thoracic surgery, and vascular surgery.
    Digital Access Springer 2018
  • Digital
    Ron Waksman, Toby Rogers.
    Summary: "The mitral valve, also known as the bicuspid or atrioventricular valve, plays a major role in controlling the transfer of blood from the left atrium to the left ventricle. There are two main types of mitral valve disease that can lead to mitral regurgitation: degenerative, in which the leaflets or the sub-valvular apparatus are deformed, and functional, in which cardiomyopathic dilatation of the ventricle or atrium results in malcoaptation of otherwise structurally normal leaflets. In reality, mitral regurgitation is often caused by a combination of both degenerative and functional processes"-- Provided by publisher.

    Contents:
    Cover
    Title Page
    Copyright Page
    Contents
    List of Contributors
    Introduction-The Mitral Book
    Chapter 1 The Pathology of Mitral Valve Disease
    1.1 Introduction
    1.2 General Anatomy of the Mitral Valve
    1.2.1 Mitral Annulus
    1.2.2 Leaflets
    1.2.3 Chordae Tendineae and Papillary Muscles
    1.2.4 Papillary Muscles and Left Ventricle
    1.3 Pathology of Mitral Valve
    1.3.1 Mitral Valve Stenosis
    1.3.2 Aging Changes and Mitral Annulus Calcification (MAC)
    1.3.3 Acute Mitral Regurgitation
    1.3.4 Chronic Mitral Regurgitation
    1.3.5 Degenerative MR
    Myxomatous Degeneration of the Mitral Valve
    1.3.6 Functional MR
    References
    Chapter 2 The Importance of Minimally Invasive Approaches for Mitral Valve Repair
    2.1 Introduction to Minimally Invasive Mitral Valve Surgery
    2.2 The Importance of MICS MVS
    2.3 Patient Selection
    2.4 Surgical Setup-Fibrillating Heart MVS
    2.5 Alternatives for Cannulation
    2.6 Alternatives to Myocardial Protection
    2.7 Mitral Valve Repair
    2.8 Outcomes
    2.9 Initiating Minimally Invasive Mitral Valve Repair Program
    2.10 Conclusion
    References
    Chapter 3 When to Intervene-Should Surgical Guidelines Apply to Transcatheter Techniques in Treating Mitral Regurgitation?
    3.1 Introduction
    3.2 Primary MR
    3.2.1 Current Guideline Recommendations
    3.2.2 Transcatheter Therapies-New Guideline Applications?
    3.3 Secondary MR
    3.3.1 Current Guideline Recommendations
    3.4 Conclusions
    References
    Chapter 4 Transcatheter Mitral Valve Therapies: A Three-Dimensional Echocardiographic View
    4.1 Introduction
    4.1.1 Mitral Valve Anatomy
    4.1.2 Mitral Valve Structure and Function
    4.1.3 Mitral Regurgitation Severity
    4.1.4 Diagnosis of MR Severity: Proximal Isovelocity Surface Area Method
    4.1.5 Diagnosis of MR Severity: Vena Contracta Method. 4.1.6 Primary and Secondary MR
    4.1.7 Mitral Regurgitation and Cardiovascular Death and Morbidity
    4.1.8 Screening for MitraClip Suitability
    4.1.9 MitraClip Procedure Guidance
    4.1.10 Transseptal Puncture
    4.1.11 MitraClip Delivery Guidance
    4.1.12 Adequacy of MitraClip Implantation Assessment
    4.1.13 Other Technologies
    4.2 Conclusions
    References
    Chapter 5 CMR Assessment of Mitral Regurgitation
    5.1 Introduction
    5.2 Pulse Sequences Used in CMR
    5.2.1 Cine Imaging
    5.2.2 Phase Contrast Imaging
    5.3 Assessment of MR Severity
    5.3.1 Qualitative Assessment
    5.3.2 Quantitative Assessment
    5.3.3 Technical Considerations for the Quantitative Assessment of MR by CMR
    5.4 Identification of MR Etiology
    5.4.1 Primary MR
    5.4.2 Secondary MR
    5.5 The Role of CMR Assessment of MR in Clinical Practice
    5.6 Conclusions
    References
    Chapter 6 CT Planning for TMVR and Predicting LVOT Obstruction
    6.1 Introduction
    6.2 History of Imaging for Mitral Valve Disease
    6.2.1 TAVR CT Planning
    6.2.2 Surgical and Transcatheter Mitral Interventions
    6.3 Concept of Aortic and Mitral Valve Technology Development
    6.4 Basics of CT Imaging Acquisition
    6.5 Definition of Mitral Valve and TMVR device Landing Zone
    6.6 Definition of LVOT
    6.7 CT Methods for Neo-LVOT prediction modeling
    6.8 CT Validation of Neo-LVOT Prediction Modeling Post-TMVR
    6.9 Correlation Between Pre- and Post-TMVR CT Neo-LVOT Prediction Modeling
    6.10 What Else Has CT Planning for TMVR Taught Us?
    Acknowledgments
    References
    Chapter 7 General Principles and State-of-the-Art Echocardiographic Evaluation of the Mitral Valve
    7.1 Introduction
    7.2 Mechanism and Etiology of Chronic MR
    7.2.1 Transthoracic Echocardiography
    7.2.2.1 Color Flow Doppler
    7.2.2 Qualitative Assessment
    7.2.2.1 Color Flow Doppler. 7.3 Continuous Wave (CW) Density Jet
    7.3.1 Semi-Quantitative Assessment
    7.3.1.1 VC Width
    7.4 Pulmonary Vein Flow/Mitral Inflow
    7.4.1 Quantitative Assessment
    7.5 Selection of Best Candidates for Interventions of the Mitral Valve
    7.5.1 Echocardiographic Criteria of COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) Trial
    References
    Chapter 8 Intraprocedural Echocardiography for MitraClip
    8.1 Introduction
    8.2 Pre-Procedure Evaluation
    8.3 Importance of the Baseline Study - TEE
    8.4 The Transseptal Puncture
    8.5 Guiding MitraClip System to Mitral Valve
    8.6 Intraprocedural Guidance of Clip within Mitral Valve and Leaflets
    8.7 Post-Clip-Deployment Assessment of Mitral Valve Function
    8.8 Assessment of Complications and Iatrogenic ASD
    References
    Chapter 9 Intraprocedural Echocardiography for Transcatheter Mitral Valve Replacement
    9.1 Introduction
    9.2 Baseline Mitral Valve Assessment
    9.3 Access to the Left Atrium, Left Ventricle, and Mitral Valve
    9.4 Predeployment and Deployment Monitoring
    9.5 Postdeployment Evaluation
    References
    Chapter 10 Transcatheter Repair: MitraClip for Degenerative Mitral Regurgitation
    10.1 Surgery for Degenerative Mitral Regurgitation
    10.2 Evidence Base for MitraClip
    10.3 Challenges for the MitraClip Procedure
    10.4 Evaluation of MitraClip for Less than Prohibitive-Risk DMR Patients
    10.5 Future Directions for MitraClip and Alternative Approaches for Leaflet Repair
    10.6 Summary
    References
    Chapter 11 MitraClip™ for Secondary Mitral Regurgitation
    11.1 Introduction
    11.2 European and US Clinical Practice Guidelines
    11.3 The MitraClip System
    11.4 MitraClip Preprocedural Planning
    11.5 Surgical Outcomes Data. 11.6 The COAPT and MITRA-FR Trials
    11.7 Summary and Conclusions
    References
    Chapter 12 The Edwards PASCAL Transcatheter Valve Repair System
    12.1 Introduction
    12.2 The Edwards PASCAL™ Transcatheter Valve Repair System
    12.3 Implantation Procedure
    12.4 Compassionate-Use and Early Feasibility Data
    12.5 Future Developments
    References
    Chapter 13 The Development of a Novel Percutaneous Treatment for Secondary Mitral Regurgitation-The Carillon® Mitral Contour System®
    13.1 Introduction
    13.2 REDUCE-FMR
    13.3 The CARILLON Trial
    13.4 Summary
    References
    Chapter 14 A Fully Percutaneous Mitral Ring: The Cardioband System
    14.1 Introduction
    14.2 Mitral Annulus Anatomy
    14.3 Pathophysiological Role of the Mitral Annulus in Mitral Regurgitation
    14.3.1 Mitral Annulus in FMR
    14.3.2 Mitral Annulus in DMR
    14.4 Surgical Annuloplasty in Mitral Regurgitation
    14.5 The Cardioband System: Description of the Device
    14.6 Procedural Planning
    14.7 Clinical Studies
    14.8 Possible Complications Related to the Implantation of Cardioband
    14.9 Recurrence of Mitral Regurgitation Following Cardioband Implantation
    14.10 Cardioband in Combination with Other Devices
    14.11 Conclusions
    References
    Chapter 15 Transcatheter Mitral Cerclage Annuloplasty
    15.1 Introduction
    15.2 Cerclage Anatomy and Function
    15.3 Limitations of Coronary Sinus Annuloplasty
    15.4 Cerclage Annuloplasty Device
    15.5 The Cerclage Procedure
    15.6 Preclinical Experiments
    15.7 Initial Human Experience
    15.8 Future Directions
    15.9 Summary
    Competing Interests
    References
    Chapter 16 The Transapical Off-Pump Mitral Valve Repair with the NeoChord Implantation (TOP-MINI)
    16.1 Introduction
    16.2 Technology
    16.3 Patient Selection
    16.4 Procedure
    16.5 Echocardiographic Guidance
    16.6 Examples. 16.6.1 Ideal Anatomy
    16.6.2 Acceptable Anatomy
    16.6.3 Challenging Anatomy
    16.6.4 Data
    16.7 Conclusion
    References
    Chapter 17 AltaValve™-A Transcatheter Mitral Valve Regurgitation Treatment Technology
    17.1 Clinical Need
    17.2 Device Description
    17.2.1 Principle of Operation
    17.2.2 Device Construction
    17.2.2.1 Stent
    17.2.2.2 Stent Cap
    17.2.2.3 Tissue Valve
    17.2.2.4 Fabric Skirts and Sutures
    17.2.3 Delivery Systems
    17.3 Anatomical Imaging and Sizing
    17.4 Preclinical and Clinical Experience
    17.4.1 Animal Studies
    17.5 Human Clinical Experience
    17.6 Summary
    References
    Chapter 18 The ARTO Transcatheter Mitral Valve Repair System
    18.1 Device Description
    18.2 Procedural Details
    18.3 Clinical Experience with the ARTO System
    18.4 Unique Features of the ARTO System
    References
    Chapter 19 Transcatheter Mitral Annuloplasty: The Millipede Device
    19.1 Background
    19.2 The Millipede Device
    19.3 Millipede Implantation Procedure
    19.4 Surgical Millipede Implants
    19.5 Millipede Clinical Results
    19.6 Clinical Implications
    19.7 Summary
    Author Disclosures
    References
    Chapter 20 Transapical and Transseptal Access for Transcatheter Mitral Valve Replacement: Techniques and Devices
    20.1 Introduction
    20.2 Transapical Approach
    20.2.1 Technique
    20.2.2 Devices in Active Clinical Trial Phase
    20.2.2.1 Tendyne
    20.2.2.2 Intrepid
    20.2.2.3 CardiAQ
    20.2.2.4 TIARA
    20.2.2.5 HighLife
    20.3 Transseptal Approach
    20.3.1 Technique
    20.3.2 Devices in Active Clinical Trial Phase
    20.3.2.1 Sapien M3
    20.3.2.2 EVOQUE
    20.3.2.3 Caisson
    20.4 Conclusions
    References
    Chapter 21 Mitral Valve-in-Valve and Valve-in-Ring Therapies
    21.1 Overview
    21.2 Evidence
    21.3 Procedure Planning
    21.4 Procedure.
    Digital Access Wiley 2021
  • Digital
    Grzegorz Smolka, Wojciech Wojakowski, Michal Tendera, editors.
    Summary: Representing the first book to offer complete coverage of all related topics, this title provides up-to-date guidance on exactly why, when, and how to perform transcatheter paravalvular leak closure. An international panel of leading experts in the field address the entire spectrum of associated problems, from relevant anatomy, to imaging methods, to implantation techniques, to a comprehensive presentation of clinical data. Specific topics covered in this book include the mechanisms of artificial valve dehiscence, with a focus on local anatomical conditions; data on conservative and surgical treatment; qualification for paravalvular leak closure; multimodality imaging techniques; a step-by-step description of access, device selection and implantation; practical tips and tricks for troubleshooting; and the latest clinical data on transcatheter paravalvular leak closure. The book facilitates the application of contemporary knowledge in clinical cardiology, cardiac surgery, imaging and interventional cardiology in the management of patients with this challenging clinical problem.

    Contents:
    1. Surgical Aspects of Paravalvular Leak
    2. The Role of Imaging in Paravalvular Leak Assessment
    3. Transcatheter Paravalvular Leak Closure
    History, Available Devices
    4. Occlutech® Paravalvular Leak Device (pld)
    5. Echo-Guiding During Transcatheter Paravalvular leak Closure
    6. Fusion Imaging for Paravalvular Leak Closure
    7. Transcatheter Closure of Paravalvular Leaks
    Procedural Aspects
    8. Mitral Paravalvaular Leak Closure:the Apical Approach
    9. Paravalvular Leakage After Transcatheter Aortic Valve Implantation
    European Experience
    10. Transcatheter Management of Tavi-Associated Paravalvular Leak
    us Experience
    11. Complications of Paravalvular Leak Closure
    12. Summary.
    Digital Access Springer 2017
  • Digital
    Marcin Zielinski, Ramón Rami-Porta, editors.
    Summary: Use of the transcervical approach in thoracic surgery has advanced significantly during the past 60 years, owing primarily to advances in technology. Nevertheless, the possibilities of this approach have never been compiled in a systematic way. This book aims to rectify the situation by describing, in a structured way, all the thoracic procedures that can be performed using the transcervical approach. Indications and contraindications, surgical techniques, complications, and results are all covered, based on the authors' experience and published reports. The contents encompass diverse surgical endoscopic procedures for diagnosis and staging, use of the transcervical approach for surgery to the thymus and mediastinum, lungs and bronchi, trachea, and esophagus, and miscellaneous items including the role of robotic surgery.

    Contents:
    Scalene Fat Pad Biopsy
    Mediastinoscopy
    Extended Cervical Mediastinoscopy
    Remediastinoscopy
    Cervical Mediastino-Thoracoscopy
    Cervical Incision Thoracic Endoscopic Surgery (CITES)
    Cervical Video-Assisted Thoracoscopic Surgery (C-VATS)
    Mediastinoscopic Ultrasonography (MUS) as a Surgical Adjuvant in Lung Cancer Staging
    Video-Assisted Mediastinoscopic Lymphadenectomy (VAMLA)
    Transcervical Extended Mediastinal Lymphadenectomy (TEMLA): The Standard Procedure and Its Variations
    Transcervical Thymectomy and Extended Thymectomy with Bilateral Opening of the Mediastinal Pleura
    Technique of the Transcervical-Subxiphoid-Videothoracoscopic Maximal Thymectomy
    Rethymectomy in the Treatment of Refractory Myasthenia Gravis: Operative Technique Through the Transcervical Approach
    Transcervical Resection of Mediastinal Tumors
    Miscellaneous Indications of the Transcervical Approach to the Mediastinum
    Transcervical Right and Left Upper Pulmonary Lobectomies
    Transcervical Approach of the Main Bronchus
    Tracheal Resection
    Oesophageal Procedures
    Transcervical Robotic Access in Thoracic Surgery: Feasibility and Alternatives
    Future Perspectives of the Use of the Transcervical Approach.
    Digital Access Springer 2014
  • Digital
    André Brunoni, Michael Nitsche, Colleen Loo, editors.
    Contents:
    Part I. Introduction and mechanisms of action
    1. Historical aspects of transcranial electric stimulation
    2. The new modalities of transcranial electric stimulation: tACS, tRNS, and other approaches
    3. Physiology of transcranial direct and alternating current stimulation
    4. Computer-based models of tDCS and tACS
    5. Animal studies in the field of transcranial electric stimulation
    6. Cortical inhibition and excitation in neuropsychiatric disorders using transcranial magnetic stimulation
    7. Neurocognitive effects of tDCS in the healthy brain
    8. Transcranial direct current stimulation in social and emotion research
    9. Multimodal association of tDCS with electroencephalography
    10. tDCS and magnetic resonance imaging
    11. Target engagement with transcranial current stimulation
    12. Cerebellar and spinal tDCS
    Part II. Applications of tDCS in neuropsychiatric disorders
    13. Mood disorders
    14. Schizophrenia
    15. OCD, anxiety disorders, and PTSD
    16. Neurodegenerative cognitive disorders
    17. Impulsivity and substance-use disorders
    18. Epilepsy
    19. Pain syndromes
    20. Stroke
    21. Transcranial direct current stimulation in disorders of consciousness
    Part III. The clinical use of tDCS
    22. Safety and tolerability
    23. Home-based tDCS: design, feasibility and safety considerations
    24. Ethical aspects of tDCS use in neuropsychiatry and the risk of misuse
    25. Regulatory aspects
    26. Clinical research and methodological aspects for tDCS research
    Index.
    Digital Access Springer 2016
  • Digital
    André R. Brunoni, Michael A. Nitsche, Colleen K. Loo, editors.
    Summary: The 2nd edition of this book incorporates the tremendous clinical advances that have occurred in the field of transcranial direct current stimulation (tDCS) over the past 5 years. Since the 1st edition was published, the clinical use of tDCS has moved from its infancy, and is now in a thrilling new phase with numerous possibilities as well as challenges. tDCS is a technique that excels in terms of safety and tolerability, and within a few years, novel technological developments will allow its use at home. At the same time, large, phase III trials have been exploring the clinical efficacy of tDCS, the results of which have been published in leading journals such as the New England Journal of Medicine and JAMA Psychiatry. This 2nd edition summarizes the state of the art of the field. Written by leading experts in the field, the book is divided into 5 parts: Introduction and Mechanisms of Action; Research Methods; tDCS in the life cycle; Applications of tDCS in neuropsychiatric disorders (further divided into Psychiatry and Neurology); and The clinical use of tDCS. It also includes several new chapters, covering topics such as precision stimulation of tDCS; combination of tDCS with different neuroimaging modalities; and use of tDCS in new clinical conditions. Moreover, all chapters have been rewritten and updated. This book is of interest to psychiatrists, neurologists and neuroscientists new to the field as well as those with a background in tDCS who want to increase their understanding of particular psychiatric conditions.

    Contents:
    Part I. Introduction and mechanisms of action
    Chapter 1. Historical aspects of transcranial electric stimulation
    Chapter 2. Basic mechanisms of transcranial alternating current and random noise stimulation
    Chapter 3. Physiology of transcranial direct and alternating current stimulation
    Chapter 4. Animal Models of tES: Methods, Techniques and Safety
    Chapter 5. Animal Studies on the Mechanisms of Low-Intensity Transcranial Electric Stimulation
    Part II. Research Methods
    Chapter 6. TMS-evoked EEG Response in Neuropsychiatric Disorders
    Chapter 7. Multimodal Association of tDCS with Electroencephalography
    Chapter 8. tDCS and Magnetic Resonance Imaging
    Chapter 9. tDCS and Functional Connectivity
    Chapter 10. The value of neuroimaging for treating depression with brain stimulation
    Chapter 11. Target Engagement with Transcranial Current Stimulation
    Chapter 12. Cerebellar and Spinal tDCS
    Chapter 13. Precision targeting of neural networks with tDCS informed by brain mapping
    Chapter 14. Clinical research and methodological aspects for tDCS research
    Part III. TDCS in the life cycle
    Chapter 15. tDCS in Child and Adolescent Psychiatry
    Chapter 16. Transcranial Direct Current Stimulation in the perinatal period
    Chapter 17. Modulating Cognition in Healthy Young Adults with tDCS
    Chapter 18. tDCS in exercise, sport performance and recovery process
    Chapter 19. Transcranial Direct Current Stimulation in Social and Emotion Research
    Chapter 20. Neurodegenerative cognitive disorders
    Part IV. Applications of tDCS in neuropsychiatric disorders
    Chapter 21. Mood disorders: clinical results
    Chapter 22. Effect of transcranial direct current stimulation on hallucinations in patients with Schizophrenia
    Chapter 23. Schizophrenia: Negative Symptoms
    Chapter 24. OCD, Anxiety Disorders, and PTSD
    Chapter 25. Cognitive functions in substance-related and addictive disorders
    Chapter 26. Transcranial Direct Current Stimulation in Substance Use Disorders
    Chapter 27. Attention-deficit/hyperactivity disorder
    Chapter 28. Cognitive effects of transcranial direct current stimulation in clinical trials
    Chapter 29. Epilepsy
    Chapter 30. Pain syndromes
    Chapter 31. Transcranial direct current stimulation for the treatment of tinnitus
    Chapter 32. Transcranial direct current stimulation in disorders of consciousness
    Chapter 33. TDCS in the Context of Rehabilitation
    Part V. The clinical use of tDCS
    Chapter 34. Safety and tolerability
    Chapter 35. Home-based tDCS: applications and approaches, design, feasibility and safety
    Chapter 36. Ethical Aspects of tDCS Use in Neuropsychiatry and the Risk of Misuse
    Chapter 37. tDCS-Pharmacotherapy interactions
    Chapter 38. Combination of tDCS with Psychotherapy and Neurobehavioral Interventions: Systematic Review and Mechanistic Principles for Future Clinical Trials
    Chapter 39. Regulatory aspects.
    Digital Access Springer 2021
  • Digital
    edited by Alexander Rotenberg, Jared Cooney Horvath, Alvaro Pascual-Leone.
    Contents:
    Transcranial magnetic stimulation (TMS) device and foundational techniques / Alexander Rotenberg, Jared Cooney Horvath, and Alvaro Pascual-Leone
    Transcranial magnetic stimulation (TMS) safety considerations and recommendations / Umer Najib and Jared Cooney Horvath
    Neuronavigation for transcranial magnetic stimulation / Roch Comeau
    Reaching deep brain structures : the h-coils / Yiftach Roth and Abraham Zangen
    Single-pulse transcranial magnetic stimulation (TMS) protocols and outcome measures / Faranak Farzan
    Paired-pulse transcranial magnetic stimulation (TMS) protocols / Andrew Vahabzadeh-Hagh
    Repetitive transcranial magnetic stimulation (rTMS) protocols / Lindsay Oberman
    Offline and online "Virtual Lesion" protocols / Shirley Fecteau and Mark Eldaief
    State-dependent transcranial magnetic stimulation (TMS) protocols / Juha Silvanto and Zaira Cattaneo
    Combination of transcranial magnetic stimulation (TMS) with functional magnetic resonance imaging / Joan A. Camprodon and Mark A. Halko
    Electroencephalography during transcranial magnetic stimulation : current modus operandi / Marine Vernet and Gregor Thut
    Transcranial magnetic stimulation (TMS) clinical applications : therapeutics / Jared Cooney Horvath, Umer Najib, and Daniel Press
    Transcranial magnetic stimulation (TMS) clinical applications : diagnostics / Josep Valls-Sole
    Review of current clinical practice in the treatment of major depression / Mark A. Demitrack and David G. Brock
    Protocol for depression treatment utilizing h-coil deep brain stimulation / Yiftach Roth and Abraham Zangen
    Navigated transcranial magnetic stimulation : principles and protocol for mapping the motor cortex / Jari Karhu, Henri Hannula, Jarmo Laine, and Jarmo Ruohonen
    Speech mapping with transcranial magnetic stimulation / Phiroz E. Tarapore.
    Digital Access Springer 2014
  • Digital
    edited by Etsuko Miyamoto-Sato [and four others].
    Contents:
    Detecting protein-protein interactions/complex components using mass spectrometry coupled techniques / Zhibin Ning ... [et al.]
    Analysis of transcription factor networks using IVV method / Hiroyuki Ohashi ... [et al.]
    Next-generation sequencing coupled with a cell-free display technology for reliable interactome of translational factors / Etsuko Miyamoto-Sato
    Chromatin immunoprecipitation protocol for mammalian cells / Makiko Komata ... [et al.]
    Detecting protein-DNA interactions using a modified yeast one-hybrid system / Kazuhisa Ota, Shu-Ying Feng,and Takashi Ito
    RNA sequencing : from sample preparation to analysis / Sho Maekawa ... [et al.]
    Detecting expressed genes using CAGE / Mitsuyoshi Murata ... [et al.]
    Tutorial to identify nonlinear associations in gene expression time series data / André Fujitaand Satoru Miyano
    Inference of TFRNs (2) / Hideo Matsuda
    Identification of the minimal connected network of transcription factors by transcriptomic and genomic data integration / Ahmed Essaghir
    Modeling and simulation using CellDesigner / Yukiko Matsuoka ... [et al.]
    Human genome network platform : a resource for TFRN analysis / Norikazu Monma, Takashi Gojobori,and Kazuho Ikeo
    Identification of transcription factors activated in thymic epithelial cells during embryonic thymus development / Taishin Akiyama ... [et al.]
    Analysis of NFATc1-centered transcription factor regulatory networks in osteoclast formation / Masahiro Shinohara and Hiroshi Takayanagi
    Transcriptional regulation in adipogenesis through PPARγ-dependent and -independent mechanisms by prostaglandins / Ko Fujimori and Yoshihiro Urade
    Analysis of TFRNs associated with steroid hormone- related cancers / Kazuhiro Ikeda, Kuniko Horie-Inoue,and Satoshi Inoue
    Repositioning monocyte TFRN into fibroblasts / Takahiro Suzuki, Jay W. Shin, and Harukazu Suzuki.
    Digital Access Springer 2014
  • Digital/Print
    Wilfried Ellmeier, Ichiro Taniuchi, editors.
    Summary: Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during Th differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity, and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.
    Digital Access Springer 2014
  • Digital
    Jiaqian Wu, Editor ; Honor editor, Dong Kim.
    Contents:
    The Analyses of Global Gene Expression and Transcription Factor Regulation
    Global Approaches to Alternative Splicing and its Regulation
    Recent Advances and Open Questions
    Long Non-coding RNAs: Critical Regulators for Cell Lineage Commitment in the Central Nervous System
    Gene expression models of signaling pathways
    From Gene Expression to Disease Phenotypes: Network-Based Approaches to Study Complex Human Diseases
    Introduction to Isoform Sequencing using Pacific Biosciences Technology (Iso-Seq)
    Systematic and Integrative Analysis of Gene Expression to Identify Feature Genes Underlying Human Diseases.
    Digital Access Springer 2016
  • Digital
    Priscilla Limbo Sagar.
    Contents:
    Nursing education and transcultural nursing / Priscilla L. Sagar
    Integrating transcultural nursing in education : academia and staff development / Priscilla L. Sagar
    Transcultural nursing in modules : academic and staff development settings / Priscilla L. Sagar
    Transcultural nursing as a separate course in nursing programs / Priscilla L. Sagar
    Integrating TCN concepts in the national council licensing examination / Priscilla L. Sagar
    Introductory nursing courses / Priscilla L. Sagar & Ann D. Corcoran
    Nursing skills / Priscilla L. Sagar & Teresa V. Hurley
    Health history and physical assessment / Drew Y. Sagar & Priscilla L. Sagar
    TCN concepts in child-bearing courses / Priscilla L. Sagar & Debra A. Hrelic
    TCN concepts in child-rearing courses / Priscilla L. Sagar
    An orthodox Jewish child with asthma : an unfolding case scenario / Barbara J. Joslyn
    TCN concepts in adult health courses / Priscilla L. Sagar & Drew Y. Sagar
    TCN concepts in older adult courses / Priscilla L. Sagar
    TCN concepts in mental health and psychiatric nursing courses / Drew Y. Sagar & Priscilla L. Sagar
    TCN concepts in pharmacology / Priscilla L. Sagar
    TCN concepts in nutrition courses / Priscilla L. Sagar
    TCN concepts in nursing research courses / Priscilla L. Sagar
    TCN concepts in community health nursing courses / Priscilla L. Sagar, Nancy Spear Owen, & Elizabeth Simon
    Professional nursing transition course / Priscilla L. Sagar
    TCN concepts in simulation / Priscilla L. Sagar
    TCN concepts in undergraduate nursing programs / Priscilla L. Sagar & Julie Coon
    TCN concepts in graduate nursing programs / Priscilla L. Sagar
    TCN concepts in faculty orientation and mentoring / Priscilla L. Sagar
    Staff orientation and professional development / Priscilla L. Sagar
    Continuing competence for nursing / Priscilla L. Sagar
    Preparing policies and procedure guidelines / Priscilla L. Sagar
    Preparing for credentialing / Priscilla L. Sagar
    Recruitment and retention of foreign educated nurses / Priscilla L. Sagar
    Then, now, and beyond: quo vadis, TCN? / Priscilla L. Sagar, Caroline Camuñas & Sheila O'Shea Melli.
    Digital Access eBook Comp Acad 2014
  • Digital
    written by Lydia Morris [and 5 others].
    Summary: Transdiagnostic Group Therapy Training and Implementation provides clinicians with a user-friendly roadmap for delivering a brief, transdiagnostic group therapy that can be used for patients suffering from stress, depression, anxiety, and a range of other related mental health problems. This is supplemented by over an hour of training videos hosted on the book's companion website, visually demonstrating how to effectively implement the therapy. The book introduces the empirical research that has led to a greater emphasis on transdiagnostic treatment approaches, and details how to implement each phase of the therapy, supported by clinical examples to make practical application easier.
    Digital Access ScienceDirect 2018
  • Digital
    Devon E. Hinton, Baland Jalal.
    Summary: "Multiplex Therapy as adapted for Muslim groups seeks to fill this gap by providing an accessible CBT treatment manual tailored primarily (but not exclusively) for Muslims living in the Western world (i.e., North America, Europe as well as Australia), including immigrants and refugees, and other subgroups such as African Americans and second, third and fourth generation American and European Muslims. The treatment manual is unique in that it takes into account the religious, spiritual, social, and cultural dimensions of individuals with a Muslim religious and/or cultural background. That is, the therapy frames treatment elements-that include mindfulness, loving-kindness meditation, attentional shifting, emotion regulation, yoga-like stretching, psychoeducation, anger management, and addressing catastrophic cognitions, pathological worry, and sleep-related problems (including sleep paralysis and nightmares)-in terms of well-known Islamic terms and concepts"-- Provided by publisher

    Contents:
    Education about anxious-depressive distress and the treatment and introduction of emotion regulation techniques
    Applied tretching and the toe-to-head muscle relaxation with visualization
    Review of toe-to-head muscle relaxation with visualization and the introduction of the dysphoria (anxiety/depression) protocol, education about anxious-depressive distress and teaching the bad memory protocol (emotion regulation toolbox)
    Education about anxious-depressive distress, modifying catastrophic cognitions, and teaching emotional distancing
    Interoception exposure I : head rotation
    Interoception exposure II : hyperventilation
    Worry and distress
    Anger and anger protocol, and education about breathing and its use for relaxation
    Somatic complaints and sleep disturbance
    Cultural syndromes and ethnophysiology related to distress.
    Digital Access Cambridge 2020
  • Digital
    Kok-Yang Tan, editor.
    Summary: This book discusses in depth the transdisciplinary integration of different components of care in colorectal surgery. Pertinent background information on the complexities of current management in colorectal surgery is first provided, followed by discussion of the role of design thinking in care integration. Subsequent chapters focus on a range of issues associated with surgical and perioperative care in patients undergoing colorectal surgery, with emphasis on how the multiple facets of care can be integrated through a transdisciplinary approach. Each chapter provides helpful take-home messages in bullet point form and numerous informative figures and tables are also included. The authors are surgeons, physicians, anesthetists, oncologists, nurses, and allied health professionals with extensive experience in the field.

    Contents:
    Complexity of Current Healthcare and Transdisciplinary Care
    Design Thinking in Care Integration
    Integrative Care for Elderly Patients
    Integrative Perioperative Nutrition
    Transdisciplinary Nursing
    Enhanced Recovery
    Integrative Pharmacology
    Transdisciplinary Prehabilitation and Rehabilitation
    Transdisciplinary Cancer Management
    Marrying Endoscopic and Laparoscopic Treatment for Colorectal Cancer
    Multimodal Approach to Familial Colorectal Cancer
    Transdisciplinary Incontinence Management
    Transdisciplinary Constipation Management
    Innovations in Perianal Care and Surgery
    Transdisciplinary Stoma Care
    Healing and Psychosocial Issues.
    Digital Access Springer 2015
  • Digital
    edited by Pierre C. Wong, Wanda C. Miller-Hance.
    Summary: Transesophageal echocardiography (TEE) has played an instrumental role among the many advances in the field of congenital heart disease (CHD) that have resulted in successful and continually improving clinical outcomes, today enabling most affected infants and children to live well into adulthood. Ongoing evolution of the technology (including three-dimensional TEE) promises to maintain this imaging approach at the forefront of clinical practice. Competent performance of TEE in the patient with CHD, however, requires a number of essential technical and cognitive skills, in addition to a solid understanding of the broad spectrum of congenital pathology. Thus, the important need for a comprehensive reference on the subject to assist specialists who care for these patients. Transesophageal Echocardiography for Congenital Heart Disease represents a unique work, the only textbook of its kind that focuses specifically upon the applications of TEE in CHD. In each chapter, the contributorshighly regarded specialists and leaders in the fieldprovide practical and instructive information on the many different aspects of CHD evaluation by TEE. The textbook is extensively supplemented with over 700 figures/illustrations and more than 400 high quality videos (available online). This reference will prove an invaluable resource for those who use TEE in the care of both children and adults with CHD, whether they be cardiologists, surgeons, anesthesiologists, intensivists, sonographers, or trainees wishing to obtain basic knowledge or advance their understanding of the field.

    Contents:
    Science of Ultrasound and Echocardiography
    Instrumentation
    Indications and Guidelines for Performance of Transesophageal Echocardiography in Congenital Heart Disease and Pediatric Acquired Heart Disease
    Structural Evaluation of the Heart by Transesophageal Echocardiography
    Functional Evaluation of the Heart by Transesophageal Echocardiography
    Systemic and Pulmonary Venous Anomalies
    Atrial Abnormalities and Atrial Septal Defects
    Atrioventricular Septal Defects and Atrioventricular Valve Anomalies
    Ventricular Septal Defects
    Evaluation of the Single Ventricle
    Outflow Tract Anomalies
    Evaluation of Conotruncal Abnormalities
    Great Artery and Other Vascular Abnormalities
    Congenital Coronary Artery Anomalies
    Intraoperative and Postoperative Transesophageal Echocardiography in Congenital Heart Disease
    Additional Applications of Transesophageal Echocardiography
    Applications of Transesophageal Echocardiography in the Cardiac Catheterization Laboratory
    Transesophageal Echocardiography in Adults with Congenital Heart Disease
    Transesophageal Three-Dimensional Echocardiography in Congenital Heart Disease
    Clinical Applications of Three-Dimensional Transesophageal Echocardiography in Congenital Heart Disease.
    Digital Access Springer 2014
  • Digital
    Pierre C. Wong, Wanda C. Miller-Hance, editors.
    Summary: This extensively revised textbook reviews the use of transesophageal echocardiography (TEE) in pediatric and young adult patients with cardiac disease. It reviews how TEE has made a vital contribution to these patients' successful and continually improving clinical outcomes, enabling them to live well into adulthood. The book details the evolving technology and applications of TEE (including three-dimensional TEE), describing how this imaging approach remains at the forefront of clinical practice for pediatric patients and those with congenital heart disease (CHD). Transesophageal Echocardiography for Pediatric and Congenital Heart Disease represents a unique contribution as the only contemporary text to focus exclusively on the clinical application of TEE in children and all patients with CHD. Written by numerous prominent specialists in the field, it presents a comprehensive, modern and integrated review of the subject. Specific chapter topics include the physics and instrumentation of TEE, structural and functional evaluation, and specialized aspects of the examination, with emphasis on the technical considerations pertinent to both pediatric and adult patients with a variety of congenital and acquired cardiovascular pathologies. Consequently, it serves as a comprehensive reference for the TEE evaluation of CHD, utilizing the segmental approach to diagnosis and discussing the TEE evaluation of the many anomalies encompassing the CHD spectrum. In addition, numerous other relevant topics are discussed, including application of TEE for perioperative and interventional settings. The book is richly illustrated, with many chapters supplemented by illustrative case studies and accompanying videos. A specific section with multiple-choice questions and answers is provided at the end of each chapter to reinforce key concepts. This textbook therefore provides an invaluable and indispensable resource for all trainees and practitioners using TEE in the management of CHD and pediatric patients.

    Contents:
    Science of Ultrasound and Echocardiography
    Instrumentation for Transesophageal Echocardiography
    Indications and Guidelines for Performance of Transesophageal Echocardiography in Congenital Heart Disease and Pediatric Acquired Heart Disease
    Structural Evaluation of the Heart by Transesophageal Echocardiography
    Evaluation of complex cardiac malpositions, dextrocardia, heterotaxy
    Functional Evaluation of the Heart by Transesophageal Echocardiography
    Systemic and Pulmonary Venous Anomalies
    Atrial Abnormalities
    Atrial Septal Defects
    Atrioventricular Septal Defects and Atrioventricular Valve Anomalies
    Ventricular Septal Defects
    Evaluation of the Single Ventricle
    Outflow Tract Anomalies
    Evaluation of Conotruncal Abnormalities
    Transposition complexes: corrected and congenitally corrected
    Great Artery and Other Vascular Abnormalities
    Congenital Coronary Artery Anomalies
    Intraoperative and Postoperative Transesophageal Echocardiography in Congenital Heart Disease
    Transesophageal echocardiography for noncongenital heart disease in pediatric patients
    Additional Applications of Transesophageal Echocardiography
    Applications of Transesophageal Echocardiography in the Cardiac Catheterization Laboratory
    Applications of TEE in the critical care/emergency care setting
    Transesophageal Echocardiography in Adults with Congenital Heart Disease
    Transesophageal Three-Dimensional Echocardiography in Congenital Heart Disease
    Clinical Applications of Three-Dimensional Transesophageal Echocardiography in Congenital Heart Disease.
    Digital Access Springer 2021
  • Digital
    Lina Normandin, Karin Ensink, Alan Weiner, Otto F. Kernberg.
    Summary: "Transference-Focused Psychotherapy for Adolescents With Severe Personality Disorders is a manual for clinicians who wish to learn an effective psychodynamic treatment for young people with personality disorders (PDs). Despite converging evidence that PDs emerge in childhood and are clearly evident in adolescence, research on effective treatments has been limited. The editors have therefore created a book that details treatment models with strong theoretical foundations and examines systematic interventions designed to explore and resolve the conflicts and behaviors, common to PDs, that impede normal adolescent development. The book begins with an overview of psychopathology and normal adolescent development from a psychodynamic perspective. The next section offers therapeutic approaches, including a discussion of the major goals and strategies of TFP-A, the clinical evaluation and assessment process, establishment of the treatment framework and collaboration with parents, and finally, the techniques and tactics of TFP-A. The last section of the book reviews the phases of treatment and discusses the strengths and competencies a therapist must have to successfully conduct transference-based therapy. Authored by experts in the field (including Dr. Kernberg, a pioneer in object relations), Transference-Focused Psychotherapy for Adolescents (TFP-A) with Severe Personality Disorders teaches clinicians how to conduct TFP-A, with the ultimate goal of resolving the intrapsychic restrictions that interfere with normal adolescent development"-- Provided by publisher.

    Contents:
    Personality disorders at adolesence : phenomenology, development, and construct validity
    Psychodynamic conceptualization of personality, development, and personality disorders in adolescence
    Major goal and strategies
    Clinical evaluation and assessment process
    Establishing the treatment frame and parent collaboration
    Techniques of TFP-A
    Tactics of TFP-A
    Phases of treatment.
  • Digital
    Koichi Sairyo, editor.
    Summary: This book presents the latest devices and techniques in transforaminal full-endoscopic lumbar discectomy (TELD). This minimally invasive procedure can be used to treat various spinal conditions, such as herniated nucleus pulposus, discogenic pain, foraminal stenosis, lateral recess stenosis, and infection. The book offers an overview of TELD, and discusses discectomy, thermal annulplasty (TA) and other trending topics. It also explores the history and anatomy of transforaminal full-endoscopic lumbar surgery, complications, TELD techniques, and TELD and TA for athletes. As such the book provides a much-needed foundation for the further development of this increasingly widespread procedure. Transforaminal Full-Endoscopic Lumbar Surgery Under the Local Anesthesia is a valuable resource for orthopedic surgeons, clinical residents and medical students, alike.

    Contents:
    Part 1 Overview
    1 History of transforaminal full-endoscopic lumbar surgery
    2 Anatomy for full-endoscopic discectomy (FED) via transforaminal approach
    3 Standard procedure of the transforaminal approach and how to perform local anesthesia (Inside-out method)
    4 Complications
    Part 2 Discectomy
    5 Inside out technique of the transforaminal full-endoscopic lumbar discectomy (TELD)
    6 Outside-in direct fragmentectomy of the TELD after foraminoplasty
    7 TELD for high school athletes
    8 Transforaminal approach for L5-s level
    Part 3 Decompression for spinal canal stenosis
    9 Full-endoscopic foraminoplasty for foraminal stenosis
    10 Full-endoscopic lateral recess decompression
    Part 4 Thermal Annulplasty (Full-endo TA)
    11 Indication and high intensity zone (HIZ)
    12 Full-endoscopic Thermal Annuloplasty for athletes
    Part 5 Others
    13 Full-endoscopic trans-Kambin's triangle lumbar interbody fusion (Fullendo-KLIF)
    14 Full-endoscopic debridement for infection.
    Digital Access Springer 2021
  • Digital
    Alexandra C.H. Nowakowski, J.E. Sumerau, and Nik M. Lampe.
    Summary: This book utilizes collaborative autoethnography to examine transformations in health and aging among queer, trans, and intersex people in society. To this end, the authors each utilize their lived experiences as queer, trans, and/or intersex people to discuss inequalities and norms in U.S. healthcare. Further, they elaborate upon some ways U.S. healthcare systems may become more inclusive of queer, trans, and intersex populations over time. In so doing, they utilize the autoethnographic cases to illustrate and describe the complexities of sex, gender, and sexualities in health and aging as well as the ways such intricacies facilitate societal inequalities in health and aging.

    Contents:
    Introduction
    You're rubber, I'm glue : navigating changing meanings of safe sex with cystic fibrosis
    Rejecting simplicity in favor of embracing the complexity of multifaceted health and aging
    Making sense of healthy embodiment after realization of intersex status.
  • Digital
    Korydon H. Smith, Pavani Kalluri Ram, editors.
    Summary: This contributed volume motivates and educates across fields about the major challenges in global health and the interdisciplinary strategies for solving them. Once the purview of public health, medicine, and nursing, global health is now an interdisciplinary endeavor that relies on expertise from anthropology to urban planning, economics to political science, geography to engineering. Scholars and practitioners in the health sciences are seeking knowledge from a wider array of fields while, simultaneously, students across majors have a growing interest in humanitarian issues and are pursuing knowledge and skills for impacting well-being across geographic and disciplinary borders. Using a highly practical approach and illustrative case studies, each chapter of this edited volume frames a particular problem and illustrates how interdisciplinary problem-solving can address the greatest challenges in global health today. In doing so, each chapter spurs critical and creative thinking about emergent and future problems. Topics explored among the chapters include: Transforming health and well-being for refugees and their communities Governing to deliver safe and affordable water The global crisis of antimicrobial resistance Low-tech, high-impact interventions to prevent neonatal mortality Communicating taboo health subjects Alternative housing delivery for slum upgrades Transforming Global Health: Interdisciplinary Challenges, Perspectives, and Strategies is a vital and timely compendium for any reader invested in improving global health equity. It will find an audience with researchers, practitioners, policymakers, and program implementers, as well as undergraduate and graduate students and faculty in the fields of global health, public health, and the health sciences.

    Contents:
    Intro
    Foreword
    Informing, Inspiring, and Mobilizing New Talent to Address Global Health Inequity
    Preface
    Introduction: The Audacity to Achieve Global Health Equity
    The "DNA" of This Book
    Additional Context
    Many Challenges Ahead
    Acknowledgments
    Contents
    Contributors
    About the Editors
    Chapter 1: Governing to Deliver Safe and Affordable Water: Perspectives from Urban Planning and Public Policy
    Introduction
    Governing the Water Commons: A Framework for Analysis
    Conflicts in Water Decisions
    Governance Arrangements/Typologies Polycentric Governance in Water Delivery
    Conclusion
    References
    Further Reading
    Chapter 2: Measuring the Lifetime Environment in LMICs: Perspectives from Epidemiology, Environmental Health, and Anthropology
    So Many Exposures!
    The Exposome Explained
    Measuring the Exposome
    Do We Need Exposome Science in LMICs?
    The Challenge of Putting It All Together
    The Challenge of Translation
    The Challenge of Research Conduct and Data Analysis
    The Challenge of Ethics
    The Role of Students in Measuring Lifetime Environments
    References Chapter 3: Transforming Well-Being for Refugees and Their Communities: Perspectives from Medicine, Nursing, Education, and Social Work
    Introduction
    Forcibly Displaced Populations
    History and Policies of Migration and Displacement
    Refugee Resettlement in the U.S.
    Forced Migration, Health, and Resilience
    Making Places: The Journey from Displacement to Emplacement
    Displaced: "In" But Not "Of"
    Emplaced: Leaving Our Imprints
    A Case Study: Buffalo, NY, the City of Good Neighbors
    Conclusion
    References Chapter 4: Interactive Systems in Nutrition: Perspectives from Epidemiology, Veterinary Science, Nutrition, Anthropology, and Community Health
    Introduction
    Malnutrition and Stunting: A Global Problem
    Current Approaches and Challenges of Nutritional Interventions
    Body: Health and Well-Being
    Food: Food System, Decision-Making, and Food Security
    Land: Land Use, Resource Allocation, and Agricultural Food Production
    Multilevel Systems: Household, Community, National/Global
    Livestock Ownership: Considering Land, Food, and Body
    What Is Livestock? Challenges Facing Livestock Production and Cultivation
    Land and Resources: A Network of Decisions Surrounding Livestock
    Climate Change and Livestock
    Livestock and the Body: Health and Well-Being
    Water Insecurity: Considering Land, Food, and the Body
    Global Importance of Water
    Water and Land: Disparity and Conflict
    Water and Food: Decisions at the Household Level
    Water and the Body: Health and Well-Being
    Conclusion
    References
    Chapter 5: Integrating Traditional and Modern Medical Practices: Perspectives from the History of Science and Medicine
    Introduction
    Digital Access Springer 2020
  • Digital
    edited by Melanie J. Norton, Nathan Rupp.
    Summary: Transforming Medical Library Staff for the Twenty-First Century focuses on how the medical library can redeploy its staff to support these new services through actively engaging and empowering them in the process. It shares best practices in developing and motivating staff to accept and welcome the changing priorities of medical libraries.

    Contents:
    The changing environment of medical libraries / Nathan Rupp and Melanie J. Norton
    Empowering staff / Teresa Knott
    Skilling up / Amy Blevins, Ryan Harris, and Elizabeth Kiscaden
    Creating the nimble organization / Jean Shipman and MJ (Mary Joan) Tooey
    Communication / Heather Holmes, Shannon D. Jones, Ana Reeves
    Managing change in a union environment / Elaine R. Martin
    Knowing and understanding the staff / Dixie Jones
    Working at the speed of scale / Michael Brewer and Gerald Perry
    Solo librarians / Meredith Solomon and Meghan Muir
    Staff recruitment, retention, and reward / Shannon D. Jones.
    Limited to 3 simultaneous users
  • Digital
    Mary Nord Cook.
    Contents:
    Introduction and background
    Parenting approaches for challenging kids; Teen and mastery of psychosocial skills; Teen: overview of format and operations
    Outcome data for PACK and MaPS teen intensive outpatient program
    PACK-Teen treatement protocol
    MaPS-Teen treatment protocol
    Conclusion.
    Digital Access ScienceDirect 2015
  • Digital
    editors, Dianne E. McCallister and Ted Hamilton.
    Summary: This unique, step-by-step guide offers a comprehensive exploration of burnout and physician wellbeing, a vital issue that steadily has become widely discussed in the professional and mainstream press. More than twenty chapter authors contribute to this multidimensional volume, including physicians, psychologists, researchers, healthcare administrators, chaplains, professional coaches, and counselors. Section one of the book establishes context, provides a brief overview of the phenomenon of physician burnout, establishes its validity, and makes a case for the reason it has emerged as a critical issue in American healthcare. Section two provides a rationale for healthcare institutions (hospitals, physician groups, medical associations) to make a commitment to physician wholeness, while section three then starts the process of delineating a step-by-step curriculum to address the dilemma, providing additional detail and personal experience direct from the frontlines of combatting burnout. Section four focuses on developing and sustaining a healthy professional culture that is aligned with the mission of the organization, and section five addresses the spiritual component of physician wholeness, Section six concludes the book with two personal essays that poignantly express the nature of two common experiences affecting physicians that require uncommon insight, patience, courage. Transforming the Heart of Practice is a major contribution to the literature and will serve as an invaluable resource for anyone concerned with addressing this crisis in American healthcare.

    Contents:
    What is The Problem?
    Physician Wellbeing in Changing Times: An Overview
    Research on Physician Burnout and Wellbeing: A Solutions-Oriented Perspective
    Why Should We Care?
    What is Our Physician Culture Now and What Does It Need to Be?
    Preventing Burnout Through Physician Integration: An Organizational Approach to Physicians That Can Improve Physicians Personal Work Life Integration
    Physician Accountability and Medicus Integra©
    Respect
    Trust
    How to Get Started?
    A Single Step and a Thousand Miles
    Physicians, Heal One Another: A Letter to Health Care Administrators
    How Doctors Are Wired
    Organizational Opportunities to Enhance Physician Learning
    What Models Have Worked in Other Places?
    Physician Wellbeing as A Matter of Mission: What We Have Learned at Adventist Health and Through the Coalition for Physician Wellbeing
    Forming a Physician Culture of Mission and Wellbeing
    Providers Mission Fit and Alignment
    New Physician Assimilation: The Role of Mentoring
    Shining a LIGHT to Wellbeing
    Collegiality and Physician Wellbeing
    Counseling, Coaching, and Consulting
    What About the Spiritual Dimension?
    Physicians and Spirituality
    Physician Wellbeing from the Perspective of Judaism, Islam, Hinduism, and Buddhism
    Spirituality and Physician Wellbeing in Multi-faith Contexts
    Mindful Living: Harnessing the Power of the Moment
    A Philosophical Rationale for a Bio-Psycho-Social-Spiritual Approach to Wellbeing
    "Remember Who You Are"
    The Journey Home: A Perspective on Integrity Through the Writings of Parker J. Palmer
    How do Particular Aspects of Life Affect Physician Wellbeing?
    Living 24/6 in a 24/7 World
    The Physician Family
    The Servant Physician
    The Physician Mother
    The Hurting Physician and Family.
    Digital Access Springer 2019
  • Digital
    William T. Choctaw.
    Contents:
    Change is Inevitable
    The Power of Common Ground
    Relentless Pursuit of Zero Harm
    The Patient Experience
    Physician Champions
    Hospital Champions
    Lean Six Sigma.
    Digital Access Springer 2016
  • Digital
    Nicole P. Juffermans, Timothy S. Walsh, editors.
    Summary: In the last decade, there have been several clinical trials that have studied red blood cell transfusion triggers in various Intensive Care Unit patient populations. Moreover, critically ill patients often suffer from coagulopathy. Recent studies have addressed the effectiveness of fresh frozen plasma and platelets to prevent or treat bleeding. This book offers a comprehensive summary of transfusion triggers for red blood cells in specific ICU patient populations and specific conditions with the aim to personalize transfusion strategy. In addition, it discusses evidence for triggers for plasma and platelets and outlines the most common adverse effects of blood transfusion in the ICU, underlining the need for a careful assessment of its risks and benefits. Transfusion in the Intensive Care Unit is a practical handbook that can be used in everyday practice to guide transfusion and thus will serve as a valuable resource for physicians, fellows and residents working in Intensive Care, Anesthesiology, and Cardiac Surgery.

    Contents:
    Introduction
    Causes of Anemia in Critically Ill Patients
    Red Blood Cell Transfusion Trigger in Sepsis
    Red Blood Cell Transfusion Trigger in Cardiac Disease
    Red Blood Cell Transfusion Trigger in Cardiac Surgery.- Red Blood Cell Transfusion Trigger in Brain Injury.- Red Blood Cell Transfusion in the Elderly
    ScvO2 as an Alternative Transfusion Trigger.- Alternatives to Red Blood Cell Transfusion.- Blood Sparing Alternatives in the Intensive Care Unit.- Massive Transfusion in Trauma
    Transfusion in Gastrointestinal Bleeding.- Platelet Transfusion Trigger in the Intensive Care Unit.- FFP Transfusion in Intensive Care Medicine.- Transfusion-Related Acute Lung Injury
    Transfusion-Associated Circulatory Overload.
    Digital Access Springer 2015
  • Digital
    Theresa Nester, editor.
    Summary: This clinical casebook covers transfusion medicine theory and its practical implications for the obstetrical hemorrhage patient through the presentation of cases on actively bleeding patients. Each case features a unique clinical scenario involving a bleeding patient and outlines different aspects of safe and effective transfusion support. The cases contain current evidence on the latest topics in the field, such as the use of antifibrinolytic agents and coagulation factor concentrates in the setting of massive obstetrical hemorrhage. In addition to the actively bleeding patient, the casebook includes other important management topics, including the role of plasma exchange in thrombotic microangiopathies during pregnancy; treatment of hyperhemolysis in a patient with hemoglobinopathy; and recommended management of patients with red cell antibodies found on prenatal testing. Other immunohematology topics such as post-natal management of an RhD negative woman for the prevention of hemolytic disease of the newborn due to anti-Rh(D) are included. Written by transfusion medicine, coagulation, obstetrical, and anesthesiology experts, Transfusion Management of the Obstetrical Patient: A Clinical Casebook is a concise yet comprehensive resource for anesthesiologists, obstetricians, pathologists, hematologists, and other practitioners who treat obstetrical hemorrhage patients.
    Digital Access Springer 2018
  • Print
    Jeffrey McCullough.
    Contents:
    History
    The blood supply
    Recruitment of blood donors
    Blood donor medical assessment and blood collection
    Blood donor medical assessment and blood collection
    Patient blood management
    Production of components by apheresis
    Laboratory testing of donated blood
    Blood groups
    Laboratory detection of blood groups and provision of red cells
    Clinical uses of blood components
    Transfusion therapy in specific clinical situations
    Techniques of blood transfusion
    Complications of transfusion
    Transfusion-transmitted diseases
    The HLA system in transfusion medicine and transplantation
    Hematopoietic growth factors in transfusion medicine
    Cellular engineering for the production of new blood components
    Therapeutic apheresis
    Quality programs in blood banking and transfusion medicine.
    Digital Access Wiley 2017
  • Digital
    edited by Jeffrey McCullough.
    Contents:
    History / Jeffrey McCullough
    The Blood Supply / Jeffrey McCullough
    Recruitment of Blood Donors / Thomas Watkins
    Blood Donor Medical Assessment and Blood Collection / Gary Bachawoski
    Preparation, Storage, and Characteristics of Blood Components and Plasma Derivatives / Alesia Kaplan
    Production of Components by Apheresis / Tomas Gniadek
    Laboratory Testing of Donated Blood / Nancy van Buren
    Blood Groups / Sarah Ilstrup
    Laboratory Detection of Blood Groups and Provision of Red Cells / Ulrike Koenigbaur
    Clinical Uses of Blood Components / Vincent LaRoche
    Transfusion Therapy in Specific Clinical Situations / James Stubbs
    Pediatric Transfusion Medicine / Stephanie Kinney
    Patient Blood Management / Jeffrey McCullough
    Pathogen Reduced Blood Products / Jeffrey McCullough
    Techniques of Blood Transfusion / Randy Covin
    Complications of Transfusion / Scott Koepsell
    Transfusion-Transmitted Diseases / Jeffrey McCullough
    The HLA System in Transfusion Medicine and Transplantation / Yoon Choo
    Cellular Engineering for the Production of Blood Components / David Stroncek, David McKenna
    Therapeutic Apheresis / Ram Reddy
    Quality Programs in Blood Banking and Transfusion Medicine / Kristin Mascotti.
    Digital Access Wiley 2021
  • Digital
    edited by Huy P. Pham, Lance A. Williams III.
    Contents:
    Cover
    Title page
    Copyright page
    Dedication
    Contents
    Contributors
    About the Editors
    Preface
    Acknowledgment
    Laboratory Reference Ranges
    Chapter 1 - Pretest
    Answers and brief explanations
    Chapter 2 - Statistics and General Principles of Laboratory Management
    Suggested Reading
    Chapter 3 - Quality Assurance and Regulatory Issues
    Suggested Reading
    Chapter 4 - Blood Donation and Collection
    Suggested Reading
    Chapter 5 - Blood Component Preparation and Storage
    Suggested Reading
    Chapter 6 - Blood Group Antigens and Antibodies
    Suggested Reading
    Chapter 7 - Pretransfusion Testing
    Suggested Reading
    Chapter 8 - Adult Transfusion-Principles and Practice
    Suggested Reading
    Chapter 9 - Patient Blood Management
    Suggested Reading
    Chapter 10 - Perinatal, Neonatal, and Pediatric Transfusion-Principles and Practice
    Acknowledgements
    Suggested Reading
    Chapter 11 - Infectious Complications of Blood Transfusion
    Acknowledgments
    Suggested Reading
    Chapter 12 - Noninfectious Risks of Transfusion
    Well-documented Indications
    Recommended Indications
    Nonindications
    Suggested Reading
    Chapter 13 - Hemostasis and Thrombosis-Laboratory Diagnosis and Treatment
    Suggested Reading
    Chapter 14 - Therapeutic and Donor Apheresis
    Suggested Reading
    Chapter 15 - Special Clinical Scenarios in Transfusion Medicine and Hemostasis
    Suggested reading
    Chapter 16 - Clinical Histocompatibility Testing
    Suggested Reading
    Chapter 17 - Cellular Therapy
    Suggested Reading
    Chapter 18 - Human Tissue Banking and Hospital-Based Surgical Tissue Management
    Suggested Reading
    Chapter 19 - Pathology Informatics
    Suggested Reading
    Chapter 20 - Practical and Advanced Calculations in Transfusion Medicine, Apheresis, and Hemostasis
    Suggested Reading
    Chapter 21 - Data Interpretation in Laboratory Medicine
    Suggested Reading
    Chapter 22 - Posttest
    Answers and brief explanations
    Index
    Back Cover
    Digital Access ScienceDirect 2018
  • Digital
    edited by Beth H. Shaz, Christopher D. Hillyer, Morayma Reyes Gil.
    Summary: "Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects, Third Edition, is the only pocket-sized, quick reference for pathology and transfusion medicine residents and fellows. It covers all topics in transfusion medicine and clinical and laboratory-based coagulation. Chapters are organized by multiple hierarchical headings and are supplemented with up to 10 suggested reading citations. This single handbook covers all the topics required to meet the goals of a major program in transfusion medicine and clinical coagulation. Changes to this edition include the latest AABB standards and new chapters focused on a wider range of specific populations requiring blood and related products. Coverage includes essential updates on peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in therapeutic apheresis and new cellular therapies"--Publisher's description.

    Contents:
    Part I: Blood banking and transfusion medicine. Blood banking
    Donation process
    Component manufacturing
    Donor testing
    Transfusion medicine
    Testing; antigens
    Blood products
    Product modifications
    Specific clinical settings
    Transfusion reactions
    Therapeutic apheresis and phlebotomy
    Cellular therapy and tissue banking
    Part II: Hemostasis clinical coagulation. Neonatal thrombocytopenia
    Inherited platelet function disorders
    Immune thrombocytopenia
    Immune medicated coagulopathies
    Congenital bleeding disorders
    Acquired bleeding disorders
    Laboratory testing of coagulation
    Screening tests
    Laboratory assessment of coagulation disorders
    Tests for hypercoagulable state
    Laboratory support of anticoagulation.
    Digital Access ClinicalKey 2019
  • Digital
    Brian Castillo, Amitava Dasgupta, Kimberly Klein, Hlaing Tint, Amer Wahed.
    Summary: Transfusion Medicine for Pathologists: A Comprehensive Review for Board Preparation, Certification, and Clinical Practice is a concise study guide designed to complement standard textbooks in the field of clinical pathology. Pathology residents and fellows of transfusion medicine will find this book useful for preparation for exams. This is a valuable time-saver for busy residents looking for a focused and compact study guide. It also serves as an excellent source of review for medical students on transfusion medicine and practicing pathologists who cross-cover transfusion medicine in their clinical practice.Incorporates key words at the end of each chapter for quick review before an examIncludes concise and easy-to-digest chapters ranging from Donor Selection and Testing, to Blood Bank Testing, Transfusion Reactions, Apheresis, Hemotherapy, Special Transfusion Situations, and moreFocuses on key topics to study for board examinations, saving time during busy residency programs
    Digital Access ScienceDirect 2018
  • Digital
    Karen Quillen.
    Summary: "Transfusion Medicine in the Hot Seat is a useful text for pathology trainees and an educational resource for pathologists who cover transfusion medicine. The text is divided into three sections: antibodies, blood components, and complications. Each section presents numerous short cases that illustrate real-world transfusion scenarios, with 26 cases total. The short-case format makes the information easily accessible and can serve as the basis for a transfusion medicine curriculum in clinical pathology."-- Provided by publisher.
  • Digital
    Hemanshu Prabhakar, Monica S Tandon, Indu Kapoor, Charu Mahajan, editors.
    Summary: Fluid management is the basis of all clinical management in neurosurgical patients. This is a complete book on transfusion practice in clinical neurosciences. It covers in detail the fluids and blood transfusion practice, also discussing the role of total parenteral nutrition in relation to neurologic patients. The importance of fluid management clinically can be seen as on one hand it plays a significant role in maintaining the hydration of the patient and on the other provides sufficient relaxation to the brain to facilitate surgery. The use of hyperosmolar therapy is unique to the practice of clinical neurosciences. Certain fluid types such as those containing glucose are detrimental to the brain. Likewise, large fluid shifts and blood loss are often observed during neurosurgical procedures. It is relevant to understand the physiology of blood and blood transfusion. This book covers all of these topics in their true relevance. It also provides an evidence-based practice of fluid administration for all neurologic patients including, pediatric and geriatric. The proposed book will be useful for trainees and clinicians in any field of clinical neurosciences. It would be very useful for residents and fellows pursuing their courses in neuroanesthesia, neurocritical care, neurosurgery, emergency medicine, anesthesia, and critical care. Fellows, Resident doctors, postgraduates, and even undergraduates would be benefited from this book. The book would be a ready-reckoner and useful during the clinical practice of physicians from varied specialties.
    Digital Access Springer 2022
  • Digital
    editors, Alex S. Keuroghlian, Jennifer Potter, Sari L. Reisner.
    Summary: "This book covers topics such as the history and background of transgender and gender-diverse health care, gender identity, primary, preventive, and specialty care, and community-building, advocacy, and partnership"-- Provided by publisher.

    Contents:
    Part I: History and background. A history of transgender and gender diverse health care: from medical mistreatment to gender-affirmative health care
    Gender identity: terminology, demographics, and epidemiology
    Health disparities
    Harnessing information technology to improve clinical care
    Part II: Gender identity emergence and affirmation in adults. Gender identity emergence and affirmation in adults
    Behavioral health considerations for transgender and gender diverse people
    Gender-affirming hormone therapy for adults
    Nonmedical, nonsurgical gender affirmation
    Surgical gender affirmation
    Case studies in gender emergence and affirmation
    Part III: Primary, preventive, and specialty care. Basic principles of trauma-informed and gender-affirming care
    Obtaining a gender-affirming sexual history
    Performing a trauma-informed physical examination
    Recognizing and addressing intimate partner violence
    Eating disorders, body image, and body positivity
    Screening and prevention of HIV and sexually transmitted infections
    Treatment of HIV and sexually transmitted infections
    Screening for cancer and cardiovascular
    Reproductive health, obstetric care, and family building
    Case studies in transgender and gender diverse primary care
    Part IV: Transgender and gender diverse populations. Transgender and gender diverse people who are black, indigenous, and people of color
    Health needs and service delivery models for transgender communities in low- and middle-income countries
    Transgender and gender diverse people and incarceration
    Caring for transgender and gender diverse veterans
    Affirming care for people with intersex traits
    Part V: Community-building, advocacy, and partnership. Community engagement and outreach
    Advocacy for transgender and gender diverse patients.
    Digital Access AccessMedicine 2022
  • Digital
    Sarah Boslaugh.
    Summary: Transgender individuals face unique challenges when it comes to their physical, psychological, and social health and well-being. This accessible reference investigates these concerns in depth, offering readers insights into topics such as discrimination and access to health care. Confronts a topic that has historically been ignored by researchers and public health officials Examines key issues that affect transgender individuals, such as discrimination and access to health services Offers illuminating case studies that use engaging real-world scenarios to highlight key ideas and debates discussed in the book Provides a Directory of Resources to guide readers to reliable sources of additional information.

    Contents:
    Part 1. Overview
    What does it mean to be transgender?
    A brief history of transgender people
    Transitioning
    Physical health
    Mental health
    part 2. Controversies and issues
    Discrimination against transgender people
    Access to health and social services and public facilities
    Transgender athletes: who competes against whom?
    Normative gender dichotomies and alternatives
    Parenting and family issues
    Research issues
    part 3. Scenarios
    Case studies.
  • Digital
    Leonid Poretsky, Wylie C. Hembree, editors.
    Summary: Although transgender persons have been present in various societies throughout human history, it is only during the last several years that they have become widely acknowledged in our society and their right to quality medical care has been established. In the United States, endocrinologists have been providing hormonal therapy for transgender individuals for decades; however, until recently, there has been only limited literature on this subject, and non-endocrine aspects of medical care for transgender individual have not been well addressed in the endocrine literature. The goal of this volume is not only to address the latest in hormonal therapy for transgender individuals (including pediatric and geriatric age groups), but also to familiarize the reader with other aspects of transgender care, including primary and surgical care, fertility preservation, and the management of HIV infection. In addition to medical issues, psychological, social, ethical and legal issues pertinent to transgender individuals add to the complexities of successful treatment of these patients. A final chapter includes extensive additional resources for both transgender patients and providers. Thus, an endocrinologist providing care to a transgender person will be able to use this single resource to address most of the patient's needs. While Transgender Medicine is intended primarily for endocrinologists, this book will be also useful to primary care physicians, surgeons providing gender-confirming procedures, mental health professionals participating in the care of transgender persons, and medical residents and students.
    Digital Access Springer 2019
  • Digital
    Yasunori Sasakura, editor.
    Summary: This book comprehensively describes the transgenesis techniques and applied experimental methods in ascidians including enthusiastically developed original devices in addition to concrete examples of developmental biology studies. Ascidians have been one of the most important model animals in developmental biology for studying molecular and cellular processes underlying formation of the chordate body plan. Transgenic techniques such as microinjection, electropolation, cis-element analysis and application, and TALENs and CRISPR/Cas9 have been developed in ascidians for more than 20 years, and now many applied methods, some of which are unique in ascidians, have been accumulated. Those extensive technological innovations, such as cell isolation, cell labeling, germ-line transformation, marker transgenic lines, and the experimental systems for studying notochord formation and nervous system, are exceptional particularly in marine invertebrates. This book is useful for ascidian researchers to quickly access the techniques in which they are interested as well as to compare each technology to become familiar with specialized tips, and for biologists of other organisms to learn the unique techniques and ingenious attempts specific to ascidians. Providing detailed and easily understandable descriptions of techniques, the book will inspire ascidian specialists to improve their techniques, encourage anyone wanting to begin studying ascidians, and enable readers to immediately apply the techniques to the organisms they research.
    Digital Access Springer 2018
  • Digital
    A.J. Larner.
    Contents:
    History of TGA
    Clinical features, diagnostic criteria, and possible variants of TGA
    Differential diagnosis of TGA
    Investigation and management of TGA
    Prognosis of TGA
    Epidemiology of TGA
    Aetiopathogenesis of TGA.
    Digital Access Springer 2017
  • Digital
    A.J. Larner.
    Summary: This extensively revised second edition provides a comprehensive overview of transient global amnesia (TGA). First, it deals with the history of TGA before moving on to clinical and diagnostic features and differential diagnosis. Subsequent chapters then discuss the investigation and predisposing and precipitating factors for TGA before attempting to synthesise these many strands in order to formulate ideas about the pathogenesis of TGA. Each of the chapters is devoted to a practical and structured overview of the particular topic, with use of case studies to illustrate the material. Based in part on the author’s experience of TGA cases over 20 years and in part on a review of the published literature, this book will hopefully enlighten clinicians from a broad range of medical backgrounds on the clinical features, investigation, and pathogenesis of TGA. Transient Global Amnesia is aimed at any clinician with an interest in, or who encounters patients with, acute amnesia: neurologists, general physicians, old age psychiatrists, geriatricians, clinical neuropsychologists, and primary care physicians, as well as other professions allied to medicine with similar interests, such as members of memory assessment teams.

    Contents:
    History of TGA
    Beginnings: Fisher and Adams' first accounts of TGA
    "Prehistory" of TGA
    After Fisher and Adams
    A note on nomenclature
    A note on methodology
    Summary and recommendations
    References
    Clinical features, diagnostic criteria, and possible variants of TGA
    Clinical features of TGA
    TGA archetype
    Accompanying neurological symptoms
    Time of onset: diurnal
    Attack duration
    Prognosis, recurrence
    Diagnostic criteria of TGA
    Essential features and inclusion/exclusion boundaries
    Hodges and Warlow’s diagnostic criteria
    TGA subtypes?
    Possible variant forms of TG
    Transient topographical amnesia (TTA)
    Transient partial verbal amnesia (TPVA)
    Transient semantic amnesia
    Transient procedural amnesia
    Transient retrograde amnesia
    Summary and recommendations
    References
    Differential diagnosis of TGA
    Transient ischaemic attack (TIA)
    Other forms of cerebrovascular disease
    Other vascular pathologies, including angiography
    Cardiac disorders
    Transient epileptic amnesia (TEA)
    Interrelation of TGA and TEA
    Transient psychological amnesia (TPA)
    Other symptomatic causes of transient amnesia
    Migraine
    Adverse drug effect
    Hypoglycaemia
    Traumatic brain (closed head) injury
    Alcohol-induced amnesia; Korsakoff syndrome
    Fatigue amnesia
    Other causes of acute cerebral disorder
    Acute confusional state/delirium/toxic-metabolic encephalopathy
    Cerebral haemorrhage
    Acute brain infection (encephalitis)
    Summary and recommendations
    References
    Investigation and management of TGA
    Neuropsychology
    Neuropsychological deficits during TGA: memory
    “Working memory”
    Anterograde memory
    Retrograde memory
    Semantic memory
    Implicit memory
    Spatial memory
    Neuropsychological deficits during TGA: other, non-memory, cognitive domains
    Language
    Visuoperceptual, visuospatial skills
    Executive function
    Neuropsychological deficits after TGA
    Neuroimaging: structural and functional
    Structural neuroimaging
    Computed tomography (CT)
    Magnetic resonance (MR) imaging
    Functional neuroimaging
    Single photon emission computed tomography (SPECT)
    Positron emission tomography (PET)
    Functional MRI (fMRI)
    MR spectroscopy (MRS)
    CT perfusion (CTP) imaging
    Neurophysiology Electroencephalography (EEG)
    EEG during TGA
    Magnetoencephalography (MEG)
    Transcranial magnetic stimulation (TMS)
    Other investigations
    Blood tests
    Cerebrospinal fluid (CSF)
    Sonography
    Arterial
    Venous; internal jugular vein valve incompetence
    Management
    Driving
    Summary and recommendation
    References
    Prognosis of TGA
    Recovery and persisting cognitive deficit
    Recurrence
    Annual recurrence rate
    Recurrent TG
    Future risk
    Cognitive decline: dementia and mild cognitive impairment (MCI)
    Cognitive decline: progressive aphasia
    Stroke
    Epilepsy
    Summary and recommendations
    References
    Epidemiology of TGA (1): Possible predisposing factors
    Incidence
    Time of onset: seasonal
    Place of onset: geographical distribution
    Patient age
    Patient gender
    Patient ethnicity
    Patient social class
    Family history of TGA
    Migraine
    Patient personality traits and psychological factors
    Vascular risk factors and stroke
    Structural brain lesions, including brain tumours
    Brain infections
    Summary and recommendations
    References
    Epidemiology of TGA (2): Possible precipitating factors
    Emotional stress
    Physical effort
    Water contact or temperature change
    Sexual activity
    Pain
    Medical procedures
    Other possible precipitating factors
    Summary and recommendations
    References
    Aetiopathogenesis of TGA
    Cerebrovascular changes
    Arterial
    Venous
    Epilepsy
    Migraine
    Genetics
    Psychiatry
    Formulation: neural network models and hypothesis
    The future?
    Summary
    References
    Index.
    Digital Access Springer 2022
  • Digital
    Gary K.K. Lau, Sarah T. Pendlebury, Peter M. Rothwell.
    Contents:
    Machine generated contents note: Section 1 Epidemiology, Risk Factors, Pathophysiology, and Causes of Transient Ischemic Attacks and Stroke
    1. Epidemiology
    2. Risk Factors
    3. Genetics
    4. Anatomy and Physiology
    5. Pathophysiology of Acute Cerebral Ischemia
    6. Causes of Transient Ischemic Attack and Ischemic Stroke
    7. Causes of Spontaneous Intracranial Hemorrhage
    Section 2 Clinical Features, Diagnosis, and Investigation
    8. Clinical Features and Differential Diagnosis of a Transient Ischemic Attack
    9. The Clinical Features and Differential Diagnosis of Acute Stroke
    10. Brain Imaging in Transient Ischemic Attack and Minor Stroke
    11. Brain Imaging in Major Acute Stroke
    12. Vascular Imaging in Transient Ischemic Attack and Stroke
    13. Non-Radiological Investigations for Transient Ischemic Attack and Stroke
    Section 3 Prognosis of Transient Ischemic Attack and Stroke
    14. Methods of Determining Prognosis Note continued: 15. Short-Term Prognosis after Transient Ischemic Attack and Minor Stroke
    16. Short-Term Prognosis after Major Stroke
    17. Long-Term Prognosis after Transient Ischemic Attack and Stroke
    Section 4 Treatment of Transient Ischemic Attack and Stroke
    18. Methods of Assessing Treatments
    19. Acute Treatment of Transient Ischemic Attack and Minor Stroke
    20. Acute Treatment of Major Stroke: General Principles
    21. Specific Treatments for Major Acute Ischemic Stroke
    22. Specific Treatment of Acute Intracerebral Hemorrhage
    23. Recovery and Rehabilitation after Stroke
    Section 5 Secondary Prevention
    24. Medical Therapies
    25. Carotid Endarterectomy
    26. Carotid Stenting and Other Interventions
    27. Selection of Patients for Carotid Intervention
    28. Intervention for Asymptomatic Carotid Stenosis
    Section 6 Miscellaneous Disorders
    29. Cerebral Venous Thrombosis
    30. Spontaneous Subarachnoid Hemorrhage Note continued: 31. Vascular Cognitive Impairment: Epidemiology, Definitions, Stroke-Associated Dementia, and Delirium
    32. Vascular Cognitive Impairment: Investigation and Treatment.
    Digital Access Cambridge 2018
  • Digital
    Yizheng Wang, editor.
    Summary: "This book discusses the latest findings on the physiological and pathological functions of transient receptor potential canonical/classical (TRPC) proteins in the brain. In addition to reviewing the functions of TRPCs in brain development and neuron transmission, it mainly covers the potential roles of TRPCs in brain disorders. TRPC proteins belong to the TRP channel superfamily, which has around 30 members. Just like TRP channels, TRPCs are non-selectively permeable to cations, with a selectivity of calcium over sodium that varies among different members. The TRPC subfamily consists of six members, grouped on the basis of the similarities in gene sequence and protein structure in mammalians. What sets TRPCs apart from other subfamilies in TRPs is that their activation, stimulated by a membrane receptor-phospholipid C (PLC) cascade, contributes to the slow and sustained elevation of intracellular free calcium. Calcium ions, one of the most important types of second messengers, mediate a variety of physiological functions in the brain, including progenitor cell proliferation, dendritic formation, synaptic transmission and neuronal survival. All TRPCs except TRPC7 have been found in various regions of the brain, including the cerebrum, cerebellum, forebrain and hippocampus. This book provides students and investigators with comprehensive information on the regulation, function and potential of TRPCs and brain diseases in order to attract more attention to this field"--Publisher's description.

    Contents:
    TRP channel classification / Hongyu Li
    TRPC channel structure and properties / Shengjie Feng
    TRPC channel downstream signaling cascades / Zhuohao He
    TRPC channels in health and disease / Yilin Tai, Shenglian Yang, Yong Liu, Wei Shao
    TRPC channels and programmed cell death / Jian Zhou, Yichang Jia
    TRPC channels and stroke / Junbo Huang
    TRPC channels and Alzheimer's disease / Rui Lu, Qian He, Junfeng Wang
    TRPC channels and Parkinson's disease / Pramod Sukumaran, Yuyang Sun, Anne Schaar, Senthil Selvaraj, Brij B. Singh
    TRPC channels and neuron development, plasticity, and activities / Yilin Tai, Yichang Jia
    TRPC channels and brain inflammation / Yoshito Mizoguchi, Akira Monji
    TRPC channels and epilepsy / Fang Zheng
    TRPC channels and mental disorders / Karina Griesi-Oliveira, Angela May Suzuki, Alysson Renato Muotri
    TRPC channels and cell proliferation / Cheng Zhan, Yu Shi
    TRPC channels and glioma / Shanshan Li, Xia Ding.
    Digital Access Springer 2017
  • Digital
    Vivien Chan, Jennifer Derenne, editors.
    Summary: This book is a collaborative effort between child and adolescent psychiatrists and adult psychiatrists, aiming to be the first resource on transitioning pediatric psychiatric patient to adult psychiatric care. Written by experts in this emerging field, the book begins by discussing the developmental presentation of many common mental health diagnoses and topics, with each chapter containing clinically-relevant features that receiving providers should consider when continuing mental health treatment from the child and adolescent system. Chapters will cover a wide range of challenges that are unique to transition-age youth. Unique developmental needs, special populations, and DSM diagnoses such as anxiety, mood, trauma, and personality disorders are discussed. Each chapter will begin with clinical pearls before delving into the specifics. Transition-Age Youth Mental Health Care is an excellent resource for all mental health professionals who may transition a late teen or early adult patient to adult psychiatric care. Child and adolescent psychiatrists, adult psychiatrists, psychologists, college mental health professionals, school administrators, social workers, and therapists will find the content practical and relevant.

    Contents:
    Transition-age youth
    Tips for child and adolescent psychiatry providers
    15 going on 26: Tips for working with transitional youth
    Developing a physician workforce to bridge the gap between pediatric and adult psychiatric care
    Anxiety disorders
    Mood disorders
    Trauma and post-traumatic stress in transitional age youth
    ADHD & learning disorders
    Eating disorders among transition age youth
    First episode & early psychosis in transition age youth
    Transition age youth with autism spectrum disorder
    Substance use disorders
    Disruptive, impulse-control and conduct disorders
    Emerging personality structures in transitional age youth
    Obsessive-compulsive and related disorders in transitional age youth
    Dilemmas in disability
    Diversity and culture
    Sexual and gender minorities in transitional age youth
    Supporting connections: A focus on the mental health needs and best practices for youth in out-of-home care transitioning to adulthood
    Reproductive health and pregnancy in transitional age youth
    What's next after high school: exploring options options through identification of individual strengths and needs
    Medical leave of absence
    Digital media use in transitional age youth: challenges and opportunities.
    Digital Access Springer 2021
  • Digital
    Hadley M. Wood, Dan Wood, editors.
    Contents:
    1. The transition process: initial assessment and development of a treatment plan
    2. Approach to the myelodysplasia patient
    3. Approach to the exstrophy patient
    4. Approach to the adult hypospadias patient
    5. Sexual function and pregnancy in the female myelodyspasia patient
    6. Revision genitoplasty, sexual function, fertility, and pelvic organ prolapse in exstrophy and the management of pregnancy
    7. Issues in the long-term management of adolescents and adults with DSD: management of gonads, genital reconstruction, and late presentation of the undiagnosed DSD
    8. The adult hypospadias patient: technical challenges in adulthood
    9. Urinary tract infections in the reconstructed bladder: evaluation and treatment options
    10. Troubleshooting continent catheterizable channels
    11. Augmentation cytosplasty: risks for malignancy and suggestions for follow-up evaluations
    12. BPH and pelvic organ prolapse in patients with neurogenic bladder
    13. Posterior urethral valves in adolescents: clinical problems, management, and follow-up
    14. Renal transplantation in patients with lower urinary tract dysfunction
    15. Management of calculi in patients with congenital neuropathic bladder
    16. Vesicoureteral reflux and the adult
    17. Adult survivors of pediatric genitourinary tumors
    Index.
    Digital Access Springer 2015
  • Digital
    Cecily L. Betz, Imelda T. Coyne, editors.
    Contents:
    Dedication by Cecily Betz and Imelda Coyne Foreword by Cecily Betz and Imelda Coyne
    Chapter 1. Introduction/OverviewCecily Betz and Imelda Coyne
    Chapter 2. Empowering young persons during the transition to adulthood (examples from Congenital Heart Disease, Belgium)Mariela Acuna Mora, Ewa-Lena Bratt, Carina Sparud-Lundin & Philip Moon
    Chapter 3. Determinants of quality of healthcare for adolescents and young adults within different cultures. DR. NABEEL ALYATEEM
    Chapter 4. Evidence base for nurses roles in the transitional care for young people with long term care. (drawing on a systematic review and examples from UK). Fiona Campbell
    Chapter 5. Analysis of self-management and transition measures for nursing practice in transition. Kathleen J. Sawin
    Chapter 6. On Your Own Feet: How to improve transitional care and young people's self-management. A practical framework for nurses (programme in Netherlands). AnneLoes van Staa, Dr. Jane Sattoe
    Chapter 7. Nurses' role in developing and monitoring for transition related outcomes Bethany Coyne
    Chapter 8. Benchmarks for transition as an initiative to improve transitional care services (examples from UK) Susie Aldiss
    Chapter 9. Transition in Cystic Fibrosis: an international experience Dr Susan Madge & Daniel Office
    Chapter 10. Adaptation of a Broad-Based Youth Transition Programme: A Nurse-Led Cystic Fibrosis Transition Initiative Anna M. Gravelle
    Chapter 11. Nurse-led effort in developing, implementing and evaluating health care transition and promoting developmentally appropriate health care in young people with bleeding disorders Prof. Deborah Christie & Prof Kate Khair
    Chapter 12. Transitional care for young adults with chronic endocrine disorders (not diabetes) Andrew Dwyer
    Chapter 13. Conclusion Cecily Betz and Imelda Coyne
    Chapter 14. Tools for Practice; research instruments that might be considered (i.e. readiness assessment; QoL measures; and so forth) Cecily Betz and Imelda Coyne.
    Digital Access Springer 2020
  • Digital
    volume editors, Michel Polak, Philippe Touraine.
    Summary: Pediatricians face many questions and challenges during patients' transition from childhood to adulthood. Chronic diseases justify long-term medical, psychological, educational, and social management. The establishment of networks with adult endocrinologists is, therefore, very important to achieving optimal conditions for a successful transition period. In this book, leading experts discuss major public health issues such as diabetes and obesity. They also review genetic diseases, including Turner syndrome and congenital adrenal hyperplasia. All clinical cases are presented in a focused way to highlight any issues which might be discussed by the doctor with patients and family. Psychological approaches are debated as are proposals for defining specific tools to encourage autonomy during this life period. This book is a valuable tool and will be helpful in answering many questions for endocrinologists, adult and pediatric, dedicated to the long-term management of patients with chronic diseases.
    Digital Access Karger 2018
  • Digital
    Cynthia D. Brown, Erin Crowley, editors.
    Summary: This book addresses an unmet need in the care of adolescents and young adults with lung disease. The increasing survival of young adults with childhood-onset pulmonary conditions is a testament to major advances in treatments and health care delivery. With the increase in survival of children with chronic respiratory conditions, there is a need for formalized transition programs to integrate adolescents and young adults into the adult model of care. This book helps fill gaps in knowledge to best achieve that initiative. This book takes a comprehensive approach to transition care in pulmonary medicine by satisfying the following objectives: 1) Understand the barriers and developmental challenges in the transition from pediatric to adult care for patients with chronic childhood-onset pulmonary disease; 2) Learn about successful evidence based transition models in pulmonary disease populations, focusing on key process and outcome measures for success; and 3) Develop knowledge to design, implement, and measure a transition program based on evidence and expert opinion. In the first section, the book outlines general principles of transition care that are applicable to all patients regardless of underlying disease process and describe best practices for performing necessary research in transition care. In the second section, the book explores psychosocial factors known to play a role in affecting transition outcomes, including parental support, psychological development, and socioeconomic factors. In the final section, transition outcomes and best practices in specific respiratory diseases are outlined. With a focus on populations with chronic pulmonary disease, this book highlights the challenges and barriers of transition, reviews model systems to understand the essential components of a transition program, and provides evidence-based information to navigate these barriers and achieve successful outcomes during transition to adulthood. This is an ideal guide for pediatric and adult pulmonary providers caring for patients who are transition age, as well as multidisciplinary care team members who work with these providers in care models on transition projects to improve the transition process. .

    Contents:
    Section 1: General Principles of Transition Care
    Chapter 1. Development of Health Care Transition Policy and Concepts
    Chapter 2. Transition Research: Approaches to Measurement and Outcomes
    Chapter 3. Training Trainees: Creating a Better Workforce to Support Transition Care
    Section 2: Psychosocial Considerations in Transition
    Chapter 4. Development and Psychosocial Challenges for Self-Management and Maintaining Adherence to Chronic Therapies
    Chapter 5. Parents in Transition: Moving from Providing to Supporting Roles
    Chapter 6. Using a Socio-Ecological Framework to Guide Transition
    Section 3: Best Practice Recommendations and Transition Outcomes in Specific Pulmonary Conditions
    Chapter 7. Providing Care for a Changing CF Population
    Chapter 8. Transition Care for Adolescents and Young Adults with Neuromuscular Disease and Chronic Pulmonary Care Needs
    Chapter 9. Establishing a Medical Home for Asthma and Other Obstructive Lung Diseases
    Chapter 10. Pulmonary Hypertension: Transition Challenges in the Current Therapeutic Era.
    Digital Access Springer 2021
  • Digital
    Sarah K. Lyons, Marisa E. Hilliard, editors.
    Summary: This unique handbook provides pediatric and adult endocrinologists and multidisciplinary clinical care providers a guide to transition from pediatric to adult care and an understanding of developmental and psychosocial issues of young adulthood and how they relate to healthcare and disease self-management. The handbook is divided into two parts. Part one describes transition interventions and novel strategies that can be integrated into routine care and gives practical considerations for transition processes from both the pediatric and adult perspectives, with applications across multiple endocrine conditions. Part two focuses on transition issues specific to common endocrine conditions – type 1 and type 2 diabetes, Turner syndrome, congenital adrenal hyperplasia, endocrine sequelae of childhood cancer, and transgender care – with condition-specific developmental and psychosocial issues, treatment and screening recommendations, healthcare process considerations, transition care guidelines, and key resources for more information. By highlighting medical, psychosocial, and healthcare delivery concerns relevant to transition to adult care, this book provides a practical, patient-centered overview of the essential information to supporting optimal adult care transition across a number of endocrine conditions. Timely and practical, Transitioning from Pediatric to Adult Care in Endocrinology: A Clinical Handbook is an excellent resource for pediatric and adult endocrinologists, behavioral healthcare providers, allied health professionals, primary care providers, and all clinical staff working with young people with endocrine conditions as they transition from children to adults.
    Digital Access Springer 2019
  • Digital
    Dan Wood, Alun Williams, Martin A. Koyle, Andrew D. Baird, editors.
    Summary: This book provides a guide to the complexities of medical care through adolescence and into adulthood. The principles of transition, the management of patients and parents, and developmentally appropriate adolescent health care are discussed and evaluated. The academic importance of understanding long-term outcomes of treatments and diseases that began in childhood is also covered. This book aims to help readers build a multidisciplinary transition team and details the barriers encountered in this process and the ways to overcome them.

    Contents:
    Introduction: what do patients worry about?
    History of adolescent care in urology
    Adolescence: an overview
    Metrics and guidelines
    Information transfer
    Managing the patients
    The importance of the specialist nurse role as part of the lifelong care of congenital conditions
    Barriers to transition
    Developmentally appropriate adolescent health care : an essential prerequisite for positive transition experiences
    Quality and safety in transitional urologic care
    Building the multidisciplinary transition team
    Political concerns in transitioning medical care
    Taking a service forward: the adolescent and adult care of major congenital anomalies - the move from adolescent to lifelong care.
    Digital Access Springer 2019
  • Digital
    edited by Janet L. Leonard.
    Summary: This book focuses on explaining the distribution of sexual systems (simultaneous hermaphroditism, sequential hermaphroditism, environmental sex determination, dioecy, androdioecy, etc.) among taxa, which remains a major challenge in evolutionary biology. Although significant advances have been made for angiosperms, there is not yet a theory that predicts the sexual system for the majority of animal taxa, and other taxa of plants also remain poorly understood. The problem, particularly for animals, is that sexual systems can be very conservative, with whole phyla and classes being characterized by a single sexual system; for example essentially the whole phylum Platyhelminthes is simultaneously hermaphroditic, whereas the Insecta (Hexapoda) and the Tetrapoda among the vertebrates, are exclusively dioecious. Sex allocation theory on the other hand, suggests that sexual systems should be highly responsive to evolution, changing with population density, life span, patterns of resource availability, etc. The book provides an overview of the topic and then presents a series of chapters, each dealing with a taxon with substantial lability in sexual system in order to identify the factors associated with changes in sexual system in each case. By doing so, the authors reveal factors that have not been considered in formal theory but seem to have a major impact on transitions between sexual systems. This book appeals to a wide readership in fields from zoology and evolutionary biology to botany.

    Contents:
    1. The Evolution of Sexual Systems in Animals
    2. The Evolution of Sexual Systems in Animals
    3. Evolutionary Transitions Between Combined and Separate Sexes
    4. The Evolution of Uniparental Reproduction in Rhabditina Nematodes: Phylogenetic patterns, Developmental Causes, and Surprising Consequences
    5. Polychaete Worms on the Brink Between Hermaphroditism and Separate Sexes
    6. Sex Determining Mechanisms in Bivalves
    7. Transitions in Sexual and Reproductive Strategies Among the Caenogastropoda
    8. Hermaphrodites, Dwarf Males, and Females: Evolutionary Transitions of Sexual Systems in Barnacles
    9. Life History Constraints Facilitate the Evolution of Androdiocy and Male Dwarfing
    10. Sexual Systems in Shrimps (infraorder Caridea Dana, 1852), with Special Reference to the Historical Origin and Adaptive Value of Protandric Simultaneous Hermaphroditism
    11. Environmental and Genetic Sex Determining Mechanisms in Fishes
    12. Causes and Consequences of Evolutionary Transitions in the Level of Phenotypic Plasticity of Reptilian Sex Determination.
    Digital Access Springer 2018
  • Digital
    editors, Laressa Bethishou, Jessica Wooster, Phung C. On.
    Summary: "This text provide complex clinical cases which will incorporate specific elements of patient care which mimic real-world practice. Unlike many pharmacotherapy cases, these cases can be used by pharmacy instructors to prompt discussion, illicit critical thinking and to illustrate the specific needs of various patient populations and health conditions during transitions of care across health care settings"-- Provided by publisher.

    Contents:
    Applying the Pharmacist Patient Care Process to Care Transitions / Laressa Bethishou, Phung C. On, Jessica Wooster
    Medication Reconciliation Best Practices / Phung C. On
    Transitions of Care at Hospital Discharge / Laressa Bethishou, Kristen Herzik
    Transitions of Care in the Outpatient Setting / Jessica Wooster
    The Importance of Addressing Financial Barriers / Jessica Wooster, Laressa Bethishou
    Communication and Health Literacy / Roxane L. Took
    ¿Hablas espanol? : Language Discordance in Transitions of Care / Danielle M. Candelario, Khyati Patel
    Addressing Patient Nonadherence / Amulya Uppala
    Trucking Along : Medication Adherence with Provider Issues / Takova D. Wallace-Gay, Rachel A. Bratteli
    Cultural Considerations during Care Transitions / Elizabeth Haftel, Phung C. On
    Hyperglycemic Crisis : Diabetic Ketoacidosis in Type 1 Diabetes / Kimberly Won, Jelena Lewis, Laressa Bethishou
    Microvascular Complications of Diabetes : Peripheral Neuropathy / Nikhil A. Sangave, Phung C. On
    Macrovascular Complications of Diabetes : Acute Kidney Injury / Rebecca L. Dunn, Jessica Wooster, Winter J. Smith
    Acute Coronary Syndromes : Non-ST Elevated Myocardial Infarction / Erika Felix-Getzik, Phung C. On
    Heart Failure with Reduced Ejection Fraction / Elizabeth A. Cook, Jessica Wooster
    Atrial Fibrillation and Stroke Prevention / Laura Tsu, Laressa Bethishou
    Optimizing Asthma Therapy Through the Continuum of Care / Luma Munjy, Laressa Bethishou, Jeffrey Gonzales
    Managing Pneumonia in Chronic Obstructive Lung Disease / Rupal Mansukhani
    Care Considerations in the Elderly / Tianrui Yang, Jessica Wooster
    Patients Experiencing Homelessness / Phung C. On, Nikhil A. Sangave
    Multimodal Pain Management Strategies / Justin P. Reinert, Don Branam, Laressa Bethishou
    Complexities of Managing Psychotherapy / Brittany L. Parmentier, Jessica Wooster.
    Digital Access AccessPharmacy 2021
  • Digital
    edited by Jeffrey Laurence, Mary Van Beusekom.
    Contents:
    Epigenetic regulation of open chromatin in pluripotent stem cells / H. Kobayashi, M. Lowe and N. Kikyo
    RNA epigenetics (epitranscriptomics) / N. Liu and T. Pan
    The nucleosome remodeling and deactylase complex in development and disease / J. Basta and M. Rauchman
    Epigenetics and muscle dysfunction in chronic obstructive pulmonary disease / E. Barreiro
    Clinical epigenetics of lung cancer / S.M. Langevin and K.T. Kelsey
    Epigenetics in cardiovascular disease / S. Aslibekyan, S.A. Claas and D.K. Arnett
    Epigenetics and arterial hypertension : evidences and perspectives / S. Friso, C.A. Carvjal, F. Pizzolo, C.E. Fardella and O. Olivieri
    Epigenetics in chronic pain / G. Bai, K. Ren and R. Dubner
    Epigenomics of alzheimer's disease / D.A. Bennett, L. Yu, J. Yang, H.-U. Klein and P.L. De Jager
    Prospective epigenetic paradigms and models for cellular senescence and epithelial-mesenchymal transition in organismal development and aging / S. Kishi, P.E. Bayliss and J. Hanai.
    Digital Access ScienceDirect 2017
  • Digital
    edited by Marisa L. Conte.
    Contents:
    Libraries supporting the translational science spectrum : an introduction / by Kristi L. Holmes
    Bioinformatics projects with the Clinical and Translational Sciences Institute : building success step by step / by Pamela L. Shaw
    Librarian involvement in tranSMART : a translational biomedical research platform / by Marci D. Brandenburg
    Librarian integration in a working group of the REDCap International Consortium / by Jennifer A. Lyon, Fatima M. Mncube-Barnes, Brenda L. Minor
    Tailoring support for a community fellows research program / by William Olmstadt, Mychal A. Vorhees, Robert J. Engeszer
    Partners in research : connecting with the community / by Kate Sayor, Molly White, Celeste Choate, Dorene Markel
    Developing an educational role in a clinical and translational science institute / by Diana Nelson Louden
    Expanding research networks / by Judith E. Smith, Leena N. Lalwani
    Librarians' roles in translating research expertise through VIVO / by Valrie I. Minson, Michele R. Tennant, Hannah F. Norton
    Connecting researchers : an intersection of game development and clinical research personnel / by Christina N. Kalinger, Jean P. Shipman, Roger A. Altizer
    Librarians partner with translational scientists : Life after My Research Assistant (MyRA) / by Jean P. Shipman
    The role of the Library in Public Access Policy compliance / by Emily S. Mazure, Patricia L. Thibodeau
    Taking flight to disseminate translational research : a partnership between the UMass Center for Clinical and Translational Science and the Library's Institutional Repository / by Lisa A. Palmer, Sally A. Gore
    Capitalizing on serendipity : parlaying a citation report into a publishing and evaluation support program / by Cathy C. Sarli, Kristi L. Holmes, Amy M. Suiter
    Research impact assessment / by Karen E. Gutzman
    Web design, evaluation and bibliometrics, oh my! From local CTSA work to national involvement / by Elizabeth C. Whipple
    Assessing impact through publications : metrics that tell a story / by Alisa Surkis.
    Limited to 3 simultaneous users
  • Digital
    Russell Weiner, Marian Kelley, editors.
    Contents:
    Foreword
    Fit-For-Purpose Validation
    Biomarkers in Drug Discovery and Development: Pre-Analytical and Analytical Considerations
    Biomarker Discovery
    Application of Quantitative Biomeasures in Early Drug Discovery
    Biomarkers in discovery and preclinical phase during drug development
    Incorporating clinical biomarkers into clinical trials
    Perspectives on Tissue Biobanking for Personalized Medicine
    The role of commercial biomarker assay kits in preclinical and clinical trials kits
    Quantification of protein biomarkers using liquid chromatography tandem mass spectrometry
    LC/MS methods for small Molecule biomarkers
    Cell-based Assays
    New Technologies for Cellular Analysis
    Flow cytometry methods for the Clinical Development of Immunomodulatory Biologics
    Key mass spectrometry techniques used in clinical biomarker research
    Clinical Genomic Biomarker Assay Development: Technologies and Issues
    Implementation of Immunohistochemistry assays for clinical trial sample analyses
    Strategic Approach to Outsourcing Clinical Biomarker Assays through CRO Relationships
    In situ hybridization (ISH) in Clinical Biomarker Development. .
    Digital Access Springer 2016
  • Digital
    Shobha N. Bhattachar, John S. Morrison, Daniel R. Mudra, David M. Bender, editors.
    Summary: Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy, acceptable safety and appropriate pharmacokinetics, all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research, personalized medicine, pre-clinical and clinical development, as well as targeted therapies--this compendium is a flexible fit, perfect for professionals in the pharmaceutical industry and related academic fields.

    Contents:
    Preface; Contents; Contributors; About the Editors; Part I: Discovery, Development and Commercialization of Drug Candidates: Overview and Issues;
    Chapter 1: Pharmaceutical Industry Performance; 1.1 Introduction; 1.1.1 Definitions; 1.1.2 Unmet Need; 1.1.3 NMEs and the Degree of Innovation; 1.2 Drug Discovery and Development Overview; 1.2.1 Learn and Confirm Cycle; 1.2.2 Process to Identify Safe and Effective Medicines; 1.3 How Medicines Work; 1.4 Drug Discovery Strategies: How Medicines Are Discovered; 1.5 Mechanistic Paradox and Precision Medicine; 1.6 Opportunities; References.
    Chapter 2: New Product Planning and the Drug Discovery-Development Interface2.1 Overview and Introduction; 2.2 Understanding the Disease State; 2.3 Customer Needs; 2.4 Does Science Matter?; 2.5 The SWOT Team or How to Look Critically at Your Program; 2.6 Those Pesky Competitors; 2.7 How to Have an RandD and Marketing Marriage Made in Heaven; 2.8 Should RandD and Marketing Collaborate Early or Late? Yes!; 2.9 RandD and Marketing Are Allies, Not Enemies; References; Part II: Druggable Targets, Discovery Technologies and Generation of Lead Molecules.
    Chapter 3: Target Engagement Measures in Preclinical Drug Discovery: Theory, Methods, and Case Studies3.1 Introduction; 3.2 Basic Concepts; 3.3 Target Engagement in Vivo; Box 1. Derivation of Eq. (3.5) for Irreversible Inhibitors; 3.4 Application to In Vivo Experimental Design; 3.4.1 Compound Delivery via Pump as a Means to Facilitate Target Validation; 3.4.2 Designing an Osmotic Pump Study; 3.4.3 Approaches to Measuring Target Engagement In Vivo; 3.4.4 The Relationship of TE to Pharmacodynamics; 3.4.5 Case Studies in Using TE. 3.4.5.1 Application of TE in a Program Exploring Insulin-Degrading Enzyme as a Potential Target for Insulin Sensitization [70]3.4.5.2 Use of TE to Establish Clinical Candidate Performance Characteristics for Aggrecanase Inhibitors as Disease-Modifying ... ; 3.5 Conclusion; References;
    Chapter 4: In Silico ADME Techniques Used in Early-Phase Drug Discovery; 4.1 Structure-Based In Silico Models; 4.1.1 Molecular Docking; 4.1.2 Molecular Dynamics; 4.2 Ligand-Based In Silico Models and Tools; 4.2.1 Quantitative Structure-Property Relationship (QSPR) Models; 4.2.1.1 Data Set Selection and Curation. 4.2.1.2 Training Set Selection4.2.1.3 Molecular Descriptors; 4.2.1.4 QSPR Model Training/Building; 4.2.1.5 QSPR Model Evaluation; 4.2.1.6 Interpretation of Model Prediction; 4.2.2 ADME QSPR Models Used at Eli Lilly and Company; 4.2.3 Prospective Validation of ADME QSPR Models at Eli Lilly and Company; 4.2.4 Trends Between Calculated Physicochemical Properties and ADME Parameters; 4.2.5 Pharmacophore Modeling; 4.2.6 Site of Metabolism Prediction; 4.2.7 SPR/STR Knowledge Extraction Using Matched Molecular Pair Analysis; 4.3 Integrated and Iterative Use of Models in Early Drug Discovery.
    Digital Access Springer 2017
  • Digital
    Beth Ann Fiedler, editor.
    Summary: This first-of-its-kind volume traces rarely explored links between public policy, the state of the environment, and key issues in public health, with recommendations for addressing longstanding intractable problems. Experts across diverse professions use their wide knowledge and experience to discuss hunger and food sustainability, land use, chronic and communicable diseases, child mortality, and global water quality. Interventions described are varied as well, from green technology breakthroughs to regulatory accountability, innovative urban planning and community policing programs. Chapters build and expand on each other's themes inspiring deeper understanding and critical thinking that further prompts readers to develop practical solutions leading to improvements in planetary and population health outcomes. Included in the coverage: · The challenge of implementing macroeconomic policy in an increasingly microeconomic world · Green aid flows: trends and opportunities for developing countries · Planning healthy communities: abating preventable chronic diseases · Foundations of community health: planning access to public facilities · International changes in environmental conditions and their personal health consequences Translating National Policy to Improve Environmental Conditions Impacting Public Health is developed for educators, students, and policymakers to generate awareness and review options to help create change in their communities. Federal agencies such as the Department of Health and Human Services, the National Institutes of Health, the EPA, and Housing and Urban Development will also find it salient.

    Contents:
    Overview of Indicators Affecting Public Health
    Home and Community Infrastructure: Energy-Efficient Housing
    Planning Healthy Communities: Abating Preventable Chronic Diseases (Childhood Obesity)
    Restoring Urban Ecosystems
    Healthy Modes of Transportation
    Resource Sharing When Designing Space for the Aging, Youth, Families
    Urban Health Access
    Sustainable Business Ventures
    Rethinking the Benefits of National Parks: Eliminating Man-made Barriers
    Making Water in the Desert (Israel).-National Perspectives on the Individual Value of Land Ownership.-National Environmental Regulation and Comparative Health Policy Literature.-Child Mortality in Pakistan: A Healthcare or Social/Environmental Issue?
    The War on Poverty and Associated Diseases
    Personal Gardens of Eden
    Environmentally Responsible Health Practices: Green Health.-Health in European Cities
    Immigration Impact in Turkey.
    Digital Access Springer 2018
  • Digital/Print
    edited by Harold J. Cook.
    Summary: "During the first period of globalization medical ideas and practices originating in China became entangled in the medical activities of other places, sometimes at long distances. They produced effects through processes of alteration once known as translation, meaning movement in place, status, and meaning."--Back cover.
    Digital Access Brill 2020
  • Digital
    Kathleen M. White, Sharon Dudley-Brown, Mary F. Terhaar, editors.
    Summary: "Designed as both a text for the DNP curriculum and a practical resource for seasoned health professionals, this acclaimed book demonstrates the importance of an interprofessional approach to translating evidence into nursing and healthcare practice in both clinical and nonclinical environments. The third edition reflects the continuing evolution of translation frameworks by expanding the Methods and Process section and providing updated exemplars illustrating actual translation work in population health, specialty practice, and the healthcare delivery system. It incorporates important new information about legal and ethical issues, the institutional review process for quality improvement and research, and teamwork and building teams for translation. Additionally, an unfolding case study on translation is threaded throughout the text"--Provided by publisher.

    Contents:
    Evidence-based practice / Kathleen M. White
    The science of translation and major frameworks / Kathleen M. White
    Change theories for translation / Kathleen M. White
    Translation of evidence for improving clinical outcomes / Julie Stanik-Hutt
    Translation of evidence for improving safety and quality / Kathleen M. White
    Translation of evidence for leadership / Mary F. Terhaar
    Translation of evidence for health policy / Kathleen M. White
    Methods for translation / Mary F. Terhaar
    Project management for translation / Mary F. Terhaar, Rachael Crickman, and Deborah S. Finnell
    Ethical responsibilities of translation of evidence and evaluation of outcomes / Mary F. Terhaar
    Data management and evaluation of translation / Martha Sylvia
    Dissemination of evidence / Sharon Dudley-Brown
    Education : an enabler of translation / Mary F. Terhaar and Marisa L. Wilson
    Information technology : a foundation for translation / Marisa L. Wilson
    Interprofessional collaboration and teamwork for translation / Kathleen M. White
    Creating a culture that promotes translation / Joyce P. Williams and Sharon Dudley-Brown
    Best practices in translation : challenges and barriers in translation / Sharon Dudley-Brown
    Legal issues in translation / Sharon Dudley-Brown
    Population health exemplars / Mary F. Terhaar
    Specialty practice exemplars / Mary F. Terhaar
    Health care system exemplars / Mary F. Terhaar.
    Digital Access R2Library 2020
    Limited to 1 simultaneous user
  • Digital
    Ying Xia, editor.
    Contents:
    Preface
    Acupuncture: A therapeutic modality, but not a placebo
    Acupuncture Styles in Current Practice
    Acupuncture Treatment for chronic fatigue syndrome
    Acupuncture Cardiovascular Regulation: Translational, Clinical Studies and Underlying Mechanisms
    Electroacupuncture Inhibition of Hypertension is Slow Onset and Long-Lasting
    Acupuncture treatment for pain: Clinical and laboratory research
    Effect of acupuncture on Parkinsons disease
    Aung Vital Energetic Alignment: The Answer to Post-Concussion Syndrome and Post-Traumatic Stress Disorder
    Acupuncture in Oncology
    Electrotherapy-An Old Technique for A New Use
    Factors Influencing Acupuncture Research
    Index.
    Digital Access Springer 2019
  • Digital
    edited by Michael J. Birrer, Lorenzo Ceppi.
    Contents:
    Origins of epithelial ovarian cancer / L. Dubeau and J. Texeira
    Ovarian cancer genomics / L. Ceppi and M.J. Birrer
    Epigenetics / J.T. Pepin, H. Cardenas, K.P. Nephew and D. Matei
    Timing of cytoreductive surgery in the treatment of advanced epithelial ovarian carcinoma / C.M. St. Clair, F. Khoury-Collado and D.S. Chi
    Angiogenesis / A.A. Secord and S. Siamakpour-Reihani
    Homologous recombination and BRCA genes in ovarian cancer / J.F. Liu and P.A. Konstantinopoulos
    Molecular basis of PARP inhibition and future opportunities in ovarian cancer therapy / B.L. Collins, A.N. Gonzalez, A. Hanbury, L. Ceppi and R.T. Penson
    Ovarian cancer / L.P. Martin and R. J. Schilder
    Novel chemotherapy tools / D.S. Dizon
    Updates on rare epithelial ovarian carcinoma / J. Bergstrom, I.-M. Shih and A.N. Fader
    Endometrial cancer genomics / M.E. Urick and D.W. Bell
    Sentinel lymph node mapping procedures in endometrial cancer / D.M. Boruta II
    The role of radiation in uterine cancer / A.L. Russo
    Novel therapies for advanced cervical cancer / K.S. Tewari
    New therapies in vulvar cancer / M.H.M. Oonk and A.G.J. van der Zee
    Fertility and cancer / M.E. Sabatini.
    Digital Access ScienceDirect 2017
  • Digital
    Qing Yan.
    Contents:
    Part 1: Concept and basic tools
    Introduction: Translational bioinformatics and personalized medicine
    Systems and dynamical medicine: The roles of translational bioinformatics
    Translational bioinformatics support for "Omics" studies: Methods and resources
    Data integration, data mining, and decision support in biomedical informatics
    Part 2: Applications in basic sciences
    Applying translational bioinformatics for biomarker discovery
    Biomarkers from systems biology and "Omics" studies: Applications and examples
    Understanding dynamical diseases: Translational bioinformatics approaches
    Part 3: Applications in clinical and translational sciences
    Translational bioinformatics methods for drug discovery and development
    Translational bioinformatics and systems biology for understanding inflammation
    Cardiovascular diseases and diabetes: Translational bioinformatics and systems biology methods
    Translational bioinformatics and systems biology for cancer precision medicine
    Aging and age-associated diseases: Translational bioinformatics and systems biology methods
    Index.
    Digital Access ScienceDirect 2017
  • Digital/Print
    Bairong Shen, Haixu Tang, Xiaoqian Jiang, editors.
    Summary: "This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level -- e.g. different omics data at the molecular level -- but also data from different levels -- the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics"--Publisher's description.

    Contents:
    NGS for sequence variants / Shaolei Teng
    RNA bioinformatics for precision medicine / Jiajia Chen, Bairong Shen
    Exploring human diseases and biological mechanisms by protein structure prediction and modeling / Juexin Wang, Joseph Luttrell IV, Ning Zhang, Saad Khan, NianQing Shi, Michael X. Wang [and others]
    Computational methods in mass spectrometry-based proteomics / Sujun Li, Haixu Tang
    Informatics for metabolomics / Kanthida Kusonmano, Wanwipa Vongsangnak, Pramote Chumnanpuen
    Metagenomics and single-cell omics data analysis for human microbiome research / Maozhen Han, Pengshuo Yang, Hao Zhou, Hongjun Li, Kang Ning
    Text mining for precision medicine: bringing structure to EHRs and biomedical literature to understand genes and health / Michael Simmons, Ayush Singhal, Zhiyong Lu
    Medical imaging informatics / William Hsu Ph.D, Suzie El-Saden, Ricky K. Taira
    LIMS and clinical data management / Yalan Chen, Yuxin Lin, Xuye Yuan, Bairong Shen
    Biobanks and their clinical application and informatics challenges / Lan Yang, Yalan Chen, Chunjiang Yu, Bairong Shen
    XML, ontologies, and their clinical applications / Chunjiang Yu, Bairong Shen
    Bayesian computation methods for inferring regulatory network models using biomedical data / Tianhai Tian
    Network-based biomedical data analysis / Yuxin Lin, Xuye Yuan, Bairong Shen.
    Digital Access Springer 2016
  • Digital
    edited by John H. Sampson.
    Contents:
    An introduction to immunotherapy in the treatment of brain tumors / J.M. Komisarow and J.H. Sampson
    Immune constitution of patients with brain tumors / J. Berry-Candelario, S.H. Farber and P.E. Fecci
    The role of regulatory t cells and indolamine-2,3-dioxygenase in brain tumor immunosuppresion / M. Dey, A.L. Chang, J. Miska, J. Qiao and M.S. Lesniak
    The role of myeloid-derived suppressor cells in immunosuppresion in brain tumors / K. Gabrusiewicz, N.A. Colwell, and A.B. Heimberger
    Tumor-specific mutations in gliomas and their implications for immunotherapy / C.J. Pirozzi, A.B. Carpenter, T. Hennika, O.J. Becher and H. Yan
    Preclinical immunotherapeutic animal models fo brain tumors / V. Chandramohan, L. Sanchez-Perez, Y. He, C.J. Pirozzi, K.L. Congdon and D.D. Bigner
    Imaging studies in immunotherapy / R.Y. Huang and D.A. Reardon
    Immunotherapy clinical trials in neuro-oncology / S. Khagi and G. Vlahovic
    Peptide-specific vaccines / P. Roth and M. Weller
    Immunotoxin therapy for brain tumors / V. Chandramohan, J.H. Sampson, I.H. Pastan and D.D. Bigner
    Checkpoint blockade immunotherapy for glioblastoma / K.A. Riccione, P. Gedeon, L. Sanchez-Perez and J.H. Sampson
    Dendritic cell therapy for brain tumors / R.G. Everson, J.P. Antonios, A.M. Tucker and L.M. Liau
    Adoptive immunotherapy against brain tumors / C. Flores, D. Mitchell and P.A. Wells
    Chimeric antigen receptor therapy of brain tumors / L. Sanchez-Perez, C.M. Suryadevara, B.D. Choi and L.A. Johnson.
    Digital Access ScienceDirect 2017
  • Digital
    Bairong Shen, editor.
    Summary: This book introduces the translational informatics applied to most aspects of virus infection, including tracking of virus origin, detection and prevention of infection, drug discovery, and vaccine design as well as smart city-level monitoring and controlling of the virus epidemic by government. It covers the informatics for data mining and modelling at molecular, tissue/organ, individual, and population levels. The informatics for immunological mechanisms and the personalized prediction and treatment of infected patients are also summarized. The perspectives on the application of artificial intelligence to the prevention of virus outbreaks are also given. This book will be helpful to readers who are interested in prevention of virus infection, biomedical informatics, and artificial intelligence in medicine and healthcare.

    Contents:
    Chapter 1. Databases, Knowledgebases and Software Tools for Virus Informatics
    Chapter 2. Detection and Prevention of Virus Infection
    Chapter 3. Bioinformatics for the Origin and Evolution of Viruses
    Chapter 4. In silico Drug Discovery for Treatment of Virus Diseases
    Chapter 5. Vaccines and Immunoinformatics for Vaccine Design
    Chapter 6. Predicting the Disease Severity of Virus Infection
    Chapter 7. Modeling the Virus Infection at the Population Level
    Chapter 8. Health-Based Geographic Information Systems for Mapping and Risk Modeling of Infectious Diseases and COVID-19 to Support Spatial Decision-Making
    Chapter 9. 5G, Big data and AI for Smart City and Prevention of Virus Infection.-.
    Digital Access Springer 2022
  • Digital
    Philip R.O. Payne, Peter J. Embi, editors.
    Contents:
    Pt. I. The rationale for translational informatics
    An introduction to translational informatics and the future of knowledge-driven healthcare
    A prototype of translational informatics in action
    pt. II. Foundations of translational informatics
    Personalized medicine
    Leveraging electronic health records for phenotyping
    Mining the bibliome
    pt. III. Applications of translational informatics
    Driving clinical and translational research using biomedical informatics
    Using big data
    In silico hypothesis discovery
    Patient engagement and consumerism
    pt. IV. The future of translational informatics and knowledge-driven healthcare
    Future directions for translational informatics.
    Digital Access Springer 2015
  • Digital
    Bairong Shen, editor.
    Summary: "This book is about the transformation of the biomedical information to smart healthcare, the chapters are designed to discuss the health associated factors such as genetics, lifestyle, nutrition and environmental factors. The interactions of these factors and the informatics for the analyses of their effects on health are also covered. The era of aging is approaching and the P4 (predictive, preventive, personalized and participatory) medicine paradigm is becoming practical and reality. According to the Kondratiev's long wave theory, IT (information technology) and health will be the next technological revolution for the new economic cycle. This book is written for biomedical informatics scientists, clinicians, health practitioners and researchers, etc."--Publisher's description.

    Contents:
    Informatics for precision medicine and healthcare / Jiajia Chen, Yuxin Lin, Bairong Shen
    Genetic test, risk prediction, and counseling / Maggie Haitian Wang, Haoyi Weng
    Newborn screening in the era of precision medicine / Lan Yang, Jiajia Chen, Bairong Shen
    Trace elements and healthcare: a bioinformatics perspective / Yan Zhang
    Tongue image analysis and its mobile app development for health diagnosis / Ratchadaporn Kanawong, Tayo Obafemi-Ajayi, Dahai Liu, Meng Zhang, Dong Xu, Ye Duan
    Physical exercise prescription in metabolic chronic disease / Laura Stefani, Giorgio Galanti
    Informatics for nutritional genetics and genomics / Yuan Gao, Jiajia Chen
    Interactions between genetics, lifestyle, and environmental factors for healthcare / Yuxin Lin, Jiajia Chen, Bairong Shen
    Cohort research in mics and preventive medicine / Yi Shen, Sheng Zhang, Jie Zhou, Jiajia Chen.
    Digital Access Springer 2017
  • Digital
    Trevor W. Robbins, Barbara J. Sahakian, editors.
    Contents:
    Translational mouse models of autism; Advancing towards pharmacological therapeutics
    Translatable and back-translatable measurement of impulsivity and compulsivity; convergent and divergent processes
    Translational models of gambling-related decision-making
    Translational research on nicotine dependence
    The need for treatment-responsive translatable biomarkers in alcoholism research
    On the road to translation for PTSD treatment: theoretical and practical considerations of the use of human models of conditioned fear for drug development
    Translational approaches targeting reconsolidation
    Translational assessment of reward and motivational deficits in psychiatric disorders
    Affective biases in humans and animals. Robinson
    Locomotor profiling from the rodents to the clinic and back again
    Animal models of sensori-motor gating in schizophrenia: Are they still relevant?
    Attention and the cholinergic system: relevance to schizophrenia
    Attentional-set-shifting across species
    Relating Translational Neuroimaging and Amperometric Endpoints: Utility for Neuropsychiatric Drug Discovery
    Cognitive translation using the rodent touchscreen test approach
    The Paired Associates Learning (PAL) Test: 30 years of CANTAB Translational Neuroscience From Laboratory to Bedside in Dementia Research
    E xperimental medicine in psychiatry new approaches in schizophrenia, depression and cognition.
    Digital Access Springer 2016
  • Digital
    Georgios P.D. Argyropoulos.
    Summary: This edited volume provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative conditions on speech and language. It brings together contributions from several leading experts in a markedly broad range of disciplines, including Speech and Language Therapy, Neuropsychology and Neurology, but also Neurosurgery, Neuroimaging and Neurostimulation, as well as Engineering and Genetics.

    Contents:
    1. Translational Neuroscience of Speech and Language Disorders: State of the Art. -2. Translational Neuroscience of Aphasia and Adult Language Rehabilitation. -3. Treatment and intervention approaches for the improvement of language abilities in neurodegenerative diseases
    4. Neural and Genetic Mechanisms of Dyslexia
    5. The role of memory systems in neurodevelopmental disorders of language
    6. Transcranial direct current stimulation (tDCS) and Language/Speech: Can patients benefit from a combined therapeutic approach?
    7. Transcranial Magnetic Stimulation in Aphasia Rehabilitation
    8. The Cerebellum: A Therapeutic Target in Treating Speech and Language Disorders
    9. Navigated rTMS for Mapping the Language Network in Preoperative Settings: Current Status and Future Prospects
    10. Presurgical Language fMRI in Epilepsy: An Introduction
    11. Lesion-symptom mapping in speech and language disorders: a translational perspective.
    Digital Access Springer 2020
  • Digital
    volume editors, A. Alonso, M.G. Hennerici, S. Meairs.
    Contents:
    Principles of cerebral ultrasound contrast imaging / Powers, J., Averkiou, M.
    Physical principles of microbubbles for ultrasound imaging and therapy / Stride, E.
    Ultrasound bio-effects and safety considerations / Ter Haar, G.
    Intima-media thickness of carotid arteries / Touboul, P.-J.
    Functional TCD : regulation of cerebral hemodynamics, cerebrovascular autoregulation, vasomotor reactivity, neurovascular coupling / Wolf, M.E.
    Intracranial perfusion imaging with ultrasound / Meairs, S., Kern, R.
    Parenchymal imaging in movement disorders / Fernandes, R.C.L., Berg, D.
    Sonothrombolysis / Meairs, S.
    Non-invasive transcranial brain ablation with high-intensity focused ultrasound / Jenne, J.W.
    Ultrasound-induced blood-brain barrier opening for drug delivery / Alonso, A.
    Digital Access Karger 2015
  • Digital
    Jukka H. Meurman, editor.
    Summary: This book is the first to be devoted to translational research - which aims to expedite the transfer of knowledge gained in the lab to clinical practice - within the field of oral health. It is examined how basic sciences and basic research are providing new methods and materials that will enable clinicians to treat patients more effectively. Readers will gain a translational perspective on a variety of oral conditions and related systemic diseases. Individual chapters are devoted to such topics as dental biomaterials, implants, and tissue engineering. The importance of evidence-based research and the roles and comparative value of preclinical and clinical trials are also highlighted. Knowledge of translational and clinical research is essential in understanding how new inventions and developments are being accomplished, and what regulations and guidelines need to be taken into account when planning studies, and not forgetting the ethical aspects of any research. Translational Oral Health Research is the first book to be devoted entirely to the subject, and it will be of interest to both researchers and practitioners.
    Digital Access Springer 2018
  • Digital
    Christoph W. Michalski, Jonas Rosendahl, Patrick Michl, Jörg Kleeff, editors.
    Summary: This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to developing the disease. There is a particular focus on intraductal papillary mucinous neoplasia as a large-scale clinical challenge in pancreatology. The next two parts focus on diagnosis, biomarkers and stratification that emphasize how various approaches to biomarker development are important as both prognostic and predictive tools. The final part consists of personalized treatment approaches that include preclinical models of pancreatic cancer and stromal, epigenetic and metabolism targeting as promising approaches to be translated into early phase clinical trials. Chapters within this part also deal with approaches that are close to being implemented in clinical practice or are already being tested in (early) clinical trials, such as those that targeting the immune systems and strategies to overcome immunotherapy resistance; phase 1 clinical trials and translational approaches in surgical treatment. Written by experts in their fields, Translational Pancreatic Cancer Research provides an outlook towards future directions by integrating information both from basic and clinical research and though demonstrating pathways to better understanding pancreatic cancer and current approaches to translating these into clinical practice.

    Contents:
    Subtypes of Pancreatic Adenocarcinoma
    Surveillance and Intervention in IPMN
    Novel Biomarkers of Invasive IPMN
    Challenges and Opportunities for Early Pancreatic Cancer Detection: Role for protein biomarkers
    Metabolic Biomarkers of Pancreatic Cancer
    Blood-Based Circulating RNAs as Preventive, Diagnostic, Prognostic and Drugable Biomarkers for Pancreatic Ductal Adenocarcinoma
    Circulating tumor DNA as a novel biomarker for pancreatic cancer
    PDAC Subtypes/Stratification
    Circulating Tumor Cells as Biomarkers in Pancreatic Cancer
    Personalized Models of Human PDAC
    Therapeutic Targeting of Stromal Components
    Epigenetic Targeting
    Targeting Metabolism
    Targeting the Immune System in Pancreatic Cancer
    Phase I Trials in Pancreatic Cancer
    Translational Approaches in Surgical Treatment.
    Digital Access Springer 2020
  • Digital
    edited by Anthony Atala, Julie G. Allickson.
    Contents:
    The landscape of cell tissues and organs / Mahendra Rao
    Landscape of cell banking / Heather C. Hatcher, Anthony Atala and Julie G. Allickson
    Cell banking: process development and cell preservation / Salem Akel
    Clinical development of placental mesenchymal stromal cells / Robert J. Hariri and Steven Fischkoff
    Translation of regenerative medicine products into the clinic in the United States: FDA perspective / Mark H. Lee, Patrick Au, John Hyde, Carmen Gacchina Johnson, Mohammad Heidaran, Safa Karandish, Lynne Boxer, Michael Mendicino, Diana Yoon, Lori Tull, Judith Arcidiacono, Brent McCright, David S. Kaplan, Donald Fink, Charles N. Durfor, Richard McFarland and Celia Witten
    Newborn stem cell banking business models / Thomas Moore, Matthew P. Brown, John R. Chapman, Jesse Kramer, Robert P. Pfotenhauer and Heather L. Brown
    Cell therapy landscape: autologous and allogeneic approaches / Nafees N. Malik and Matthew B. Durdy
    Stem cells and cell therapy: autologous cell manufacturing / Ronnda L. Bartel
    Overview: challenges of process development for cellular therapy / Robert Perry
    Tissue engineering: propagation and potency evaluation / Ivan N. Rich
    Biomaterials in preclinical approaches for engineering skeletal tissues / Márcia T. Rodrigues, Pedro P. Carvalho, Manuela E. Gomes and Rui L. Reis
    Biomaterials in regenerative medicine: considerations in early process development / Alexander M. Tatara, Anthony Ratcliffe, Mark E.K. Wong, F. Kurtis Kasper and Antonios G. Mikos
    Biomaterials in regenerative medicine: challenges in technology transfer from science to process development / Prafulla Chandra, James J. Yoo and Sang Jin Lee
    Paracrine regulation from tissue engineered constructs / Or Gadish and Elazer R. Edelman
    Creating commercial value from biomaterials / Glenn D. Prestwich and Brenda K. Mann
    Manufacturing of regenerative medicine products / Tom Spencer and Deepak Jain
    Regulatory aspects / Joyce L. Frey-Vasconcells
    Global design for clinical trials / Yoshito Ikada
    Biomarkers / Ralf Huss
    Translational animal models for regenerative medicine research / John G. Sharp
    Translational imaging for regenerative medicine / Sneha S. Kelkar and Aaron M. Mohs
    Skin and skin appendage regeneration / Krzysztof Kobielak, Eve Kandyba and Yvonne Leung
    Clinical aspects of regenerative medicine: tendon, ligament, and joint / Steven Sampson, Angie Botto-van Bemden and Danielle Aufiero
    Bone regeneration / Suzanne Stewart, Stephanie J. Bryant, Jaimo Ahn and Kurt D. Hankenson
    Regenerative medicine therapies using adipose-derived stem cells / Jolene E. Valentin, Albert D. Donnenberg, Kacey G. Marra and J. Peter Rubin
    Transplantation of myogenic cells in duchenne muscular dystrophy patients: clinical findings / Daniel Skuk and Jacques P. Tremblay
    Regeneration of the vascular system / Etai Sapoznik, Guoguang Niu, Masashi Nomi, Zhan Wang and Shay Soker
    Hematopoiesis in regenerative medicine / Graça Almeida-Porada and Christopher D. Porada
    The application and future of neural stem cells in regenerative medicine / Shreyasi Das, Brian Tobe, Paul A. Jain, Walter Niles, Alicia Winquist, Lina Mastrangelo and Evan Y. Snyder
    Central nervous system / Anup Tuladhar, Nikolaos Mitrousis, Tobias Führmann and Molly S. Shoichet
    In situ tissue engineering bone regeneration in jaw reconstruction / Robert E. Marx
    Regenerative medicine for diseases of the respiratory system / Mei Ling Lim, Philipp Jungebluth and Paolo Macchiarini
    Renal system / Joao Paulo Zambon, Prafulla Chandra, Anthony Atala and James J. Yoo
    Translational regenerative medicine
    hepatic systems / Abritee Dhal, Dipen Vyas, Emma C. Moran, Daniel B. Deegan, Shay Soker and Pedro M. Baptista
    Advances in neo-innervation of the gut / Khalil N. Bitar, Shreya Raghavan, Sita Somara, Elie Zakhem and Stephen Rego
    Genitourinary system / Mehran Abolbashari, Anthony Atala and James J. Yoo
    Clinical aspects of regenerative medicine: immune system / Erszebet Szilagyi, Premenand Sundivakkam, Tamara Nunez, Kavitha Premenand, Norma Kenyon and Amelia Bartholomew
    Development of appropriate imaging methods to trace cell fate, engraftment, and cell survival / Jesse V. Jokerst and Sanjiv S. Gambhir
    Gap analysis to target therapies / Adrian P. Gee
    Funding for the translation of regenerative medicines / Neil J. Littman, Elona Baum and Alan O. Trounson.
    Digital Access ScienceDirect 2015
  • Digital
    Erika Ruiz-Garcia, Horacio Astudillo-de la Vega, editors.
    Summary: "This book presents concise chapters written by internationally respected experts on various important aspects of translational cancer genomics, offering a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research field. Being a complex disease that affects millions of people worldwide, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. In the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient's specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and even more, considering the immune system, the metabolism and in the near future the microbiome, all areas nowadays related in the prognosis and treatment of cancer patients. These contributions are either critical reviews or clinical and basic research reports. The topics discussed here include evidence-based medicine and provides useful information on translational cancer research to clinicians and biomedical scientists in order to offer another vision of cancer origin beyond the traditional causes or the oncogenic maintenance concept proposed by the oncogene addiction theory"--Publisher's description.

    Contents:
    Pharmaco-geno-proteo-metabolomics and translational research in cancer / Edith A. Fernández-Figueroa, Saul Lino-Silva, Jorge E. Peña-Velasco, Claudia Rangel-Escareño
    Next generation sequencing (NGS): a revolutionary technology in pharmacogenomics and personalized medicine in cancer / Stefania Morganti, Paolo Tarantino, Emanuela Ferraro, Paolo D’Amico, Bruno Achutti Duso, Giuseppe Curigliano
    Pharmaco-epigenomics: on the road of translation medicine / César López-Camarillo, Dolores Gallardo-Rincón, María Elizbeth Álvarez-Sánchez, Laurence A. Marchat
    Design and implementing pharmacogenomics study in cancer / María Luisa Romero Lagunes, Francisco Emilio Vera Badillo
    Onco-omics approaches and applications in clinical trials for cancer patients / Juan-Manuel Hernandez-Martinez, Roberto Sánchez-Reyes, J. G. De la Garza-Salazar, Oscar Arrieta
    Issues and ethical considerations in pharmaco-oncogenomics / Gilberto Morgan
    Pharma-oncogenomics in the era of personal genomics: a quick guide to online resources and tools / Rohan P. Joshi, David F. Steiner, Eric Q. Konnick, Carlos J. Suarez
    Immuno-oncology in the era of personalized medicine / William R. Gwin III, Mary L. Disis, Erika Ruiz-Garcia
    CAR-T cell and personalized medicine / Marlid Cruz-Ramos, Jesús García-Foncillas
    Oncobiome at the forefront of a novel molecular mechanism to understand the microbiome and cancer / H. Astudillo-de la Vega, O. Alonso-Luna, J. Ali-Pérez, C. López-Camarillo, E. Ruiz-Garcia
    Nutrition, cancer and personalized medicine / Jóse Ali Flores-Pérez, Fabiola de la Rosa Oliva, Yacab Argenes, Abelardo Meneses-Garcia.
    Digital Access Springer 2019
  • Digital
    Colleen G. Le Prell, Edward Lobarinas, Arthur N. Popper, Richard R. Fay, editors.
    Contents:
    Preface
    Perspectives on Auditory Translation Research
    Current Issues in Clinical and Translational Research in the Hearing Sciences, Audiology, and Otolaryngology
    Auditory Processing Disorder: Biological Basis and Treatment Efficacy
    Sudden Sensorineural Hearing Loss
    Development of Drugs for Noise-Induced Hearing Loss
    Cisplatin-Induced Hearing Loss
    Past, Present, and Future Pharmacological Therapies for Tinnitus
    Developing a Molecular Therapeutic for Hearing Loss
    Photons in the Ear
    Clinical and Translational Research: Challenges to the Field
    Digital Access Springer 2016
  • Digital
    Dong-Young Noh, Wonshik Han, Masakazu Toi, editors.
    Summary: This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.
    Digital Access Springer 2021
  • Digital
    Erwei Song, Hai Hu, editors.
    Contents:
    Chap. 1 The Dawning of Translational Breast Cancer: from Bench to Bedside
    Chap. 2 Biomarker Studies in Early Detection and Prognosis of Breast Cancer
    Chap. 3 The Preventive Intervention of Hereditary Breast Cancer
    Chap. 4 Predicting and Overcoming Chemotherapeutic Resistance for Breast Cancer
    Chap. 5 Studies on DNA Damage Repair and Precision Radiotherapy for Breast Cancer
    Chap. 6 Targeted Therapies against Growth Factor Signaling in Breast Cancer
    Chap. 7 Targeting Stemness: Implications for Precision Medicine in Breast Cancer
    Chap. 8 Disrupting Tumor Angiogenesis and ?the Hunger Games? for Breast Cancer
    Chap. 9 Key Factors in Breast Cancer Dissemination and Establishment at the Bone: Past, Present and Future Perspectives
    Chap. 10 Perspectives of Reprogramming Breast Cancer Metabolism
    Chap. 11 Metabolic Changes during Cancer Cachexia Pathogenesis
    Chap. 12 Cell Cycle Regulation in Treatment of Breast Cancer
    Chap. 13 BRCA Gene Mutations and Poly (ADP-ribose) Polymerase Inhibitors in Triple-negative Breast Cancer
    Chap. 14 Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer
    Chap. 15 Progress in Vaccine Therapies for Breast Cancer
    Chap. 16 Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer
    Chap 17 New Approaches in CAR-T Cell Immunotherapy for Breast Cancer
    Chap 18 Immune Checkpoint Blockade in Breast Cancer Therapy.
    Digital Access Springer 2017
  • Digital
    Shin'ichi Takeda, Yuko Miyagoe-Suzuki, Madoka Mori-Yoshimura, editors.
    Contents:
    1. Fukuyama congenital muscular dystrophy: clinical aspects
    2. α-dystroglycanopathy
    3. Myotonic dystrophy
    4. Molecular pathogenesis and therapeutic strategy in GNE myopathy
    5. Targeting the Type I TGF-β receptor for treating caveolin-3-deficient autosomal dominant limb-girdle muscular dystrophy type 1C and muscle wasting disorders
    6. Translational research in nucleic acid therapies for muscular dystrophies
    7. Toward regenerative medicine for muscular dystrophies: lessons from regeneration processes
    8. Stem cell-based therapy for Duchenne muscular dystrophy
    9. Therapeutic apprach of iPS cell technology for testing muscular dystrophy
    10. Clinical aspects of GNE myopathy and translational medicine
    11. Patient registries for international harmonized clinical development
    12. Muscular dystropy clinical trial network in Japan
    13. Translational research on DMD in Japan: from mice to exploratory investigator-initiated clinical trial in human.
    Digital Access Springer 2016
  • Digital
    Chao Ma, Yuguang Huang, editors.
    Contents:
    Assessment of Itch and Pain in Animal Models and Human Subjects
    Allergic Contact Dermatitis: A Model of Inflammatory Itch and Pain in Human and Mouse
    Modulation of c-nociceptive Activities by Inputs from Myelinated Fibers
    New Mechanism of Bone Cancer Pain: Tumor Tissue-Derived Endogenous Formaldehyde Induced Bone Cancer Pain via TRPV1 Activation
    Neuropathic Pain: Sensory Nerve Injury or Motor Nerve Injury
    Peripheral Nociceptors as Immune Sensors in the Development of Pain and Itch
    Mas-related G protein-coupled Receptors Offer Potential New Targets for Pain Therapy
    Pain Modulation and Transition from Acute to Chronic Pain
    Advances in the Study and Treatment of Neuropathic Pain
    Integrated, team-based Chronic Pain Management: Bridges from Theory and Research to High Quality Patient care.
    Digital Access Springer 2016
  • Print
    Luciano Alves Favorito, editor.
    Summary: Translational research is of great importance for clinical practice. Therefore, this book provides comprehensive information on an important gap in pediatric urology: the description of basic concepts that allow a better understanding of urinary and genital anomalies. The content encompasses personal experience and research topics developed at Rio de Janeiro State Universitys Urogenital Research Unit over the past 25 years. Throughout the chapters, the main aspects of embryology and fetal anatomy as applied to the various congenital malformations that most often affect newborns and children are described. Neural tube defects and Prune Belly Syndrome, two rare but highly relevant conditions that alter the structure of the urinary and genital system, are discussed in detail. In addition, the diagnosis and treatment of genital anomalies are addressed. Given its scope, the book offers a valuable resource for a wide audience including urologists, pediatricians, pediatric surgeons, and medical students.

    Contents:
    Basic Embryology of Urogenital System
    Basic Anatomy of the Urinary Tract
    Basic Anatomy of the Male Genital Tract
    Basic Anatomy of the Female Genital Tract
    Testicular Migration
    Basic Research Applied to Undencended Testis
    Basic Research Applied to Testicular Torsion
    Methods of Basic Research Applied to Urinary and Genital Systems During the Human Fetal Period
    Basic Research Applied to Hypospadias
    Basic Research Applied to Renal Anomalies
    Basic Research Applied to Ureteral Anomalies
    Basic Research Applied to Bladder Anomalies
    Basic Research Applied to Female Reproductive Tract
    Neural Tube Defects and Genitourinary System
    Prune Belly Syndrome and Genitourinary System.
    Digital Access Springer 2021
  • Digital
    editors, Andrew J. Krentz, Christian Weyer and Marcus Hompes.
    Summary: This book reviews techniques for assessing insulin action, insulin secretion and body composition, with reference to new drugs, in phase 1 & 2 studies. Adds to understanding of drug effects and non-drug treatment strategies in obesity and type 2 diabetes.

    Contents:
    Part 1: Review of Clinical Investigative Methods Chapter 1: Quantifying Insulin Action in Humans Chapter 2: Assessment of Islet Alpha- and Beta-Cell Function Chapter 3: Pharmacokinetic and Pharmacodynamic Assessment of Novel and Biosimilar Insulins Chapter 4: Measurement of Energy Expenditure Chapter 5: QUANTIFYING APPETITE AND SATIETY Chapter 6: Non-invasive quantitative magnetic resonance imaging and spectroscopic biomarkers in nonalcoholic fatty liver disease and other cardiometabolic diseases associated with ectopic fat deposition Chapter 7: Structural and Functional Imaging of Muscle, Heart, Endocrine Pancreas and Kidneys in Cardiometabolic Drug Development Chapter 8: Positron emission tomography and computed tomography measurement of brown fat thermal activation: key tool for developing novel pharmacotherapeutics for obesity and diabetes Chapter 9: Isotopic Tracers for the Measurement of Metabolic Flux Rates Chapter 10: Role of Tissue Biopsy in Drug Development for NonAlcoholic Fatty Liver Disease and Other Metabolic Disorders Chapter 11: Utility of Invasive and Non-invasive Cardiovascular Research Methodologies in Drug Development for Diabetes, Obesity and NAFLD/NASH Chapter 12: Omics: Potential role in early phase drug development Part 2: Preclinical Drug Development and Transitioning to Clinical Studies Chapter 13: Peptide Drug Design for Diabetes & Related Metabolic Diseases Chapter 14: ANIMAL MODELS OF TYPE 2 DIABETES, OBESITY AND NONALCOHOLIC STEATOHEPATITIS
    CLINICAL TRANSLATABILITY AND APPLICABILITY IN PRECLINICAL DRUG DEVELOPMENT Chapter 15: Drug Development for Diabetes Mellitus: Beyond Hemoglobin A1c Chapter 16: Emerging Circulating Biomarkers For The Diagnosis And Assessment Of Treatment Responses In Patients With Hepatic Fat Accumulation, Nash And Liver Fibrosis Chapter 17: Quantitative Approaches in Translational Cardiometabolic Research: An Overview Chapter 18: Transitioning from Preclinical to Clinical Drug Development Chapter 19: Regulatory Considerations for Early Study and Clinical Development of Drugs for Diabetes, Obesity, NonAlcoholic Steatohepatitis (NASH) and other Cardiometabolic Disorders Chapter 20: Early Phase Metabolic Research with Reference to Special Populations.
    Digital Access Springer 2019
  • Digital
    Andrew J. Krentz, Lutz Heinemann, Marcu Hompesch, editors.
    Summary: This book aims to aid the selection of the most appropriate techniques for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, and related cardiometabolic disease. Clinical research methods for assessing the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycaemic clamp technique, have become well-established in proof-of-mechanism studies; however, selection of the best techniques is by no means straightforward. This book will aid the understanding of the need for new pharmacotherapies for type 1 diabetes, type 2 diabetes, and obesity and the molecular targets of drugs currently in development. Emerging technologies including the omics disciplines are considered together with practical and ethical issues of early phase clinical trials in subjects with cardiometabolic disorders. Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development will be of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.

    Contents:
    1. Review of physiology/pathophysiology
    2. Methods for assessing insulin action in humans
    3. Assessment of insulin secretion
    4. Measurement of ectopic fat in liver and muscle using magnetic resonance spectroscopy
    5. Isotopic tracers for the measurement of metabolic flux
    6. Measuring food intake in clinical drug development
    7. Measurement of energy expenditure
    8. Assessment of body composition
    9. Assessment of cardiovascular safety of new diabetes drugs.
    Digital Access Springer 2015
  • Digital
    Yoram Vodovotz, Gary An.
    Contents:
    Ch. 1.1. Interesting times: the translational dilemma and the need for translational systems biology of inflammation
    Ch. 2.1. A brief history of the philosophical basis of the scientific endeavor: how we know what we know, and how to know more
    Ch. 2.2. A brief history of biomedical research up to the molecular biology revolution
    Ch. 2.3. Biomedical research since the molecular revolution: an embarrassment of riches
    Ch. 2.4. Randomized clinical trials: a bridge too far?
    Ch. 2.5. Complexity in biomedical research: mysticism versus methods
    Ch. 2.6. Human nature, politics, and translational inertia
    Ch. 3.1. Towards translational systems biology of inflammation
    Ch. 3.2. Dynamic knowledge representation and the power of model making
    Ch. 3.3. A roadmap for a rational future: a systematic path for the design and implementation of new therapeutics
    Ch. 4.1. From data to knowledge in translational systems biology: an overview of computational approaches across the scientific cycle
    Ch. 4.2. Data-driven and statistical models: everything old is new again
    Ch. 4.3. Mechanistic modeling of critical illness using equations
    Ch. 4.4. Agent-based modeling and translational systems biology: an evolution in parallel
    Ch. 4.5. Getting science to scale: accelerating the development of translational computational models
    Ch. 5.1. What is old is new again: the scientific cycle in the twenty-first century and beyond
    Index.
    Digital Access ScienceDirect 2015
  • Digital
    edited by Michael D. Waters, Claude L. Hughes.
    Contents:
    Introduction: The Case for Concern about Mutation and Cancer Susceptibility during Critical Windows of Development and the Opportunity to Translate Toxicology into a Therapeutic Discipline. What Stressors Cause Cancer and When? / Claude L Hughes, Michael D Waters
    What Mutagenic Events Contribute to Human Cancer and Genetic Disease? / Michael D Waters
    Developmental Origins of Cancer / Suryanarayana V Vulimiri, John M Rogers
    The Mechanistic Basis of Cancer Prevention / Bernard W Stewart
    Exposures that Could Alter the Risk of Cancer Occurrence, and Impact Its Indolent or Aggressive Behavior and Progression Over Time. Diet Factors in Cancer Risk / Lynnette R Ferguson
    Voluntary Exposures: Natural Herbals, Supplements, and Substances of Abuse - What Evidence Distinguishes Therapeutic from Adverse Responses? / Eli P Crapper, Kylie Wasser, Katelyn J Foster, Warren G Foster
    Voluntary Exposures: Pharmaceutical Chemicals in Prescription and Over-the-Counter Drugs - Passing the Testing Gauntlet / Ronald D Snyder
    Children's and Adult Involuntary and Occupational Exposures and Cancer / Annamaria Colacci, Monica Vaccari
    Gene-Environment Interactions. Ethnicity, Geographic Location, and Cancer / Fengyu Zhang
    Dietary/Supplemental Interventions and Personal Dietary Preferences for Cancer: Translational Toxicology Therapeutic Portfolio for Cancer Risk Reduction / Sandeep Kaur, Elaine Trujillo, Harold Seifried
    Social Determinants of Health and the Environmental Exposures: A Promising Partnership / Lauren Fordyce, David Berrigan, Shobha Srinivasan
    Categorical and Pleiotropic Nonmutagenic Modes of Action of Toxicants: Causality. Bisphenol A and Nongenotoxic Drivers of Cancer / Natalie R Gassman, Samuel H Wilson
    Toxicoepigenetics and Effects on Life Course Disease Susceptibility / Luke Montrose, Jaclyn M Goodrich, Dana C Dolinoy
    Tumor-Promoting/Associated Inflammation and the Microenvironment: A State of the Science and New Horizons / William H Bisson, Amedeo Amedei, Lorenzo Memeo, Stefano Forte, Dean W Felsher
    Metabolic Dysregulation in Environmental Carcinogenesis and Toxicology / R Brooks Robey
    Biomarkers for Detecting Premalignant Effects and Responses to Protective Therapies during Critical Windows of Development. Circulating Molecular and Cellular Biomarkers in Cancer / Ilaria Chiodi, A Ivana Scovassi, Chiara Mondello
    Global Profiling Platforms and Data Integration to Inform Systems Biology and Translational Toxicology / Barbara A Wetmore
    Developing a Translational Toxicology Therapeutic Portfolio for Cancer Risk Reduction / Rebecca Johnson, David Kerr
    Ethical Considerations in Developing Strategies for Protecting Fetuses, Neonates, Children, and Adolescents from Exposures to Hazardous Environmental Agents / David B Resnik, Melissa J Mills.
    Digital Access Wiley 2018
  • Digital
    Hugo Miguel Baptista Carreira dos Santos, editor.
    Summary: Translational Urinomics provides an overview of urine analysis using proteomics, metabolomics, transcriptomics or any combination thereof for the diagnosis and prognosis of diseases related to the urinary system and the kidneys. The text approaches urine biomarkers from a new perspective, incorporating up-to-date studies of mass-spectrometry-based biomarker discovery as well as the latest advances in personalized medicine. The integration of technology-driven techniques, such as OMICS also provides a unique opportunity for improved diagnostics accuracy of urinary-related diseases. For nephrologists and urologists looking for new approaches to well-known problems, this edited volume serves as a valuable guide.

    Contents:
    1. Sample Preparation for High-Throughput Urine Proteomics Using 96-Well Polyvinylidene Fluoride (PVDF) Membranes
    2. Kidney diseases: the age of molecular markers
    3. Urinary Extracellular Vesicles Magic particles for biomarker discovery
    4. Cardiac troponin T: the impact of posttranslational modifications on analytical immunoreactivity in blood up to the excretion in urine
    5. Research Progress of Urine Biomarkers in the Diagnosis, Treatment, and Prognosis of Bladder Cancer
    6. Urinary markers of podocyte dysfunction in chronic glomerulonephritis
    7. On Research and Translation of Urinary Biomarkers
    8. A Mechanistic-Based and Non-Invasive Approach to Quantify the Capability of Kidney to Detoxify Cysteine-Disulfides
    9. Diagnosis of Fluorosis by analysis of fluoride content in body fluids using ion selective electrode method
    10. Dioctophimosis: a Parasitic Zoonosis of Public Health Importance.
    Digital Access Springer 2021
  • Digital
    [edited by] Aldo C. Stamm ; associate editor, João Mangussi-Gomes.
    Summary: "Transnasal endoscopic skull base and brain surgery have undergone major technical advances in recent years. The accumulation of experience and exciting technological innovations - including high-definition cameras, more ergonomic and precise surgical instruments, as well as new hemostatic agents - have enabled safer and more efficacious treatment of lesions affecting highly complex and delicate regions. This fully revised and updated second edition builds on the acclaimed first edition, focusing on the correlation between endoscopic skull base anatomy and state-of-the-art clinical applications. Among these are the transplanum/transtuberculum, transcribrifom, transclival, and craniocervical junction surgical approaches"--Provided by publisher.

    Contents:
    Machine generated contents note:
    Section I. Principles of Transnasal Endoscopic Skull Base and Brain Surgery
    Section II. Management of the Paranasal Sinuses in Transnasal Endoscopic Skull Base and Brain Surgery
    Section III. Transnasal Endoscopic Approach to the Orbit and Optic Nerve
    Section IV. Transnasal Endoscopic Transcribriform Approach
    Section V. Transnasal Endoscopic Transplanum/Transtuberculum Approach
    Section VI.Transnasal Endoscopic Sellar and Parasellar Approaches
    Section VII. Transnasal Endoscopic Transclival Surgery
    Section VIII. Transnasal Endoscopic Transmaxillary/Transpterygoid/Infratemporal Fossa Approaches
    Section IX. Transnasal Endoscopic Approach to the Petrous Apex and Meckel's Cave
    Section X. Transnasal Endoscopic Surgery for Sinus and Skull Base Malignancies
    Section XI. Transnasal Endoscopic Craniocervical Junction Surgery
    Section XII. Transnasal Endoscopic Skull Base and Brain Surgery in Children
    Section XIII. Ventral Skull Base Cerebrospinal Fluid Leaks and Meningo/Encephaloceles
    Section XIV. Complications in Transnasal Endoscopic Skull Base and Brain Surgery.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Neurosurgery
    Thieme MedOne Otolaryngology
  • Digital
    [edited by] Manuel Bernal-Sprekelsen, Isabel Vilaseca.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Otolaryngology
  • Digital
    Russell, Jonathon O.; Inabnet III, William B.; Tufano, Ralph P.
    Digital Access Springer 2020
  • Digital
    Claudio Vicini, Paul T. Hoff, Filippo Montevecchi, editors.
    Contents:
    Part I: Patient Work-Up
    2. Tongue Pathophysiology in OSAS Patients: A Surgically Oriented Perspective
    3. History-Taking and Clinical Examination
    4. Sleep Studies
    5. Imaging
    6. Drug Induced Sedation Endoscopy (DISE)
    7. Patient Selection
    Part II: Surgery.
    8. Transoral Robotic Surgery as Single Level Surgery for Treatment of Obstructive Sleep Apnea
    9. TORS in a Multilevel Procedure
    10. Alternative Procedures
    11. Robotic Setting
    12. Surgical Anatomy in Trans-oral Robotic Procedure: Basic Fundamentals
    13. Trans Oral Robotic Surgery for Obstructive Sleep Apnea Syndrome: An Anesthetists Point of View
    14. Technique: How We do It
    Part III: Post-Operative Concerns
    15. Post-Operative Management of Trans-Oral Robotic Surgery for Obstructive Sleep Apnea
    16. Expected Outcomes
    17. Complication Management
    18. Short- and Long-term Dysphagia
    19. Failures Management
    Part IV: TORS for OSAS in Geographic Perspective: How to Run a Program in Different Countries
    20. The North American Experience
    21. The South American Experience
    22.The European Experience
    23. The Middle East Experience
    24. The Far Eastern Experience
    25. The Australian Experience
    Part V: Research and Future Perspectives
    26. Research and Future Perspectives.
    Digital Access Springer 2016
  • Print
    Lesley A. Sharp.
    Summary: " In The Transplant Imaginary, author Lesley Sharp explores the extraordinarily surgically successful realm of organ transplantation, which is plagued worldwide by the scarcity of donated human parts, a quandary that generates ongoing debates over the marketing of organs as patients die waiting for replacements. These widespread anxieties within and beyond medicine over organ scarcity inspire seemingly futuristic trajectories in other fields. Especially prominent, longstanding, and promising domains include xenotransplantation, or efforts to cull fleshy organs from animals for human use, and bioengineering, a field peopled with "tinkerers" intent on designing implantable mechanical devices, where the heart is of special interest. Scarcity, suffering, and sacrifice are pervasive and, seemingly, inescapable themes that frame the transplant imaginary. Xenotransplant experts and bioengineers at work in labs in five Anglophone countries share a marked determination to eliminate scarcity and human suffering, certain that their efforts might one day altogether eliminate any need for parts of human origin. A premise that drives Sharp's compelling ethnographic project is that high-stakes experimentation inspires moral thinking, informing scientists' determination to redirect the surgical trajectory of transplantation and, ultimately, alter the integrity of the human form. "-- Provided by publisher.

    Contents:
    Introduction: Moral Neutrality in Experimental Science
    1. The Reconfigured Body of the Transplant Imaginary
    2. Hybrid Bodies and Animal Science: The Promises of Interspecies Proximity
    3. Artificial Life: Perfecting the Mechanical Heart
    4. Temporality and Social Desire in Anticipatory Science
    Conclusion: The Moral Parameters of Virtuous Science
    Notes
    References
    Index.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RD120.7 .S492 2014
    1
  • Digital
    editors: Per Ljungman, David Snydman, Michael Boeckh.
    Contents:
    Part I. Introduction to transplant infections
    Part II. Risks and epidemiology of infections after transplantation
    Part III. Specific sites of infection
    Part IV. Bacterial infections
    Part V. Viral infections
    Part VI. Fungal infections
    Part VII. Other infections
    Part VIII. Infection Control
    Part IX. Immune reconstitution strategies for prevention and treatment of infections
    Part X. Hot topics
    Index.
    Digital Access Springer 2016
  • Digital
    American Nurses Association, International Transplant Nursing Society.
    Contents:
    Contributors
    Overview of content
    Scope of Transplant Nursing Practice
    Standards of transplant nursing practice
    Standards of practice for transplant nursing
    Standards of professional performance for transplant nursing
    Glossary
    References and bibliography
    Appendix A : Transplant Nursing : Scope and standards of practice (2009).
    Digital Access R2Library 2016
    Limited to 1 simultaneous user
  • Digital
    Paula C. Zimbrean, Yelizaveta Sher, Catherine Crone, Andrea F. DiMartini, editors.
    Summary: This book addresses the challenges clinicians face when working with patients facing complicated medical diagnosis for which transplantation is considered. Written by experts in transplant psychiatry, each chapter approaches a common psychiatric challenge faced by transplant candidates and recipients. Chapters meticulously share clinical expertise that provides a framework for future discussions without neglecting the fact that each transplant patient is unique in the complexity of their medical diagnosis. Additionally, the book examines comorbidities in which few specialists have received training, including transplant-related posttraumatic stress disorder, post-transplant cognitive impairment, the collaboration between mental health and transplant clinicians, postoperative seizures, and a wide range of other complicated topics. Transplant Psychiatry is an excellent case-based guide to mental healthcare delivery for all clinicians who may work with transplant patients, including psychiatrists, transplant surgeons, internal medicine specialists, hematologists, transplant social workers and transplant coordinators.

    Contents:
    Patients journey through organ transplantation
    Mood disorders: depressive disorders
    Mood disorders: bipolar disorder spectrum
    The suicidal patient
    Psychotic disorders
    Anxiety disorders: generalized anxiety disorder
    Anxiety disorders: panic disorder
    Anxiety disorders: pre and post-transplant posttraumatic stress disorder
    Personality disorders
    Eating disorders
    Sexual identity disorders
    Delirium
    Neurocognitive disorders in the pre-transplant setting
    Intellectual disability
    Post-operative seizures
    Post-transplant persistent cognitive impairment
    Alcohol
    Opioids
    Cocaine and stimulants
    Cannabinoids
    Nicotine
    Gambling
    Relationship patient-clinicians
    Collaboration between transplant medical team and outside mental health services
    Inter-center collaborations
    The multiple roles of transplant psychiatrist
    When the psychiatrist and the transplant team disagree
    Impact of the transplantation process upon the caregiver
    Challenges with adherence with medical care
    Return to work
    Existential issues in transplantation
    Psychological adaptation post transplantation
    The choice of not pursuing organ transplantation
    Psychiatric impact of steroid treatment
    Immunosuppressants and side effects
    Children
    Psychiatric disease and decision to donate
    Donor-recipient relationship
    Unrelated and/or undirected donation
    Multiple organ donors
    Miscellaneous
    Conclusions.
    Digital Access Springer 2022
  • Digital
    Ghaneh Fananapazir, Ramit Lamba, editors.
    Digital Access Springer 2018
  • Digital
    Ronald W. Busuttil, Goran B. Klintmalm.
    Summary: Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-date guidance on every imaginable aspect of liver transplantation. Understand today's full range of transplantation techniques with complete step-by-step descriptions of each, and access the background information and management options for each hepatic disease entity. Take advantage of detailed discussions of everything from pathophysiology and patient and donor selection, to transplantation anesthesia and operative procedures; immunosuppression; postoperative care; and ethical issues.

    Contents:
    The history of liver transplantation
    Surgical anatomy of the liver
    Molecular and cellular basis of liver failure
    Influence of transplantation on liver surgery
    Organ allocation : the U.S. model
    Organ allocation : the European models
    Donation after cardiac or brain death : regulatory and ethical principles
    Current indications, contraindications, delisting criteria, and timing for transplantation
    Transplantation for hepatitis A and B
    Natural history of hepatitis C
    Transplantation for hepatitis C
    Transplantation for fulminant hepatic failure
    Transplantation for primary biliary cirrhosis
    Transplantation for sclerosing cholangitis
    Transplantation for autoimmune hepatitis
    Transplantation for primary hepatic malignancy
    Transplantation for cholangiocarcinoma
    Transplantation for metastases
    Transplantation for hematological disorders
    Transplantation for Budd-Chiari syndrome
    Transplantation for alcoholic liver disease
    Transplantation for nonalcoholic steatohepatitis
    Unusual indications for transplantation
    General criteria for transplantation in children
    Transplantation for cholestatic liver disease in children
    Transplantation for biliary atresia in children
    Transplantation for metabolic disease in children
    Transplantation for hepatic malignancy in children
    Ethical decisions in transplantation
    Psychiatric assessment of liver transplant candidates
    Pretransplantation evaluation : cardiac
    Pretransplantation evaluation : renal
    Pretransplantation evaluation : infectious disease
    Role of the clinical nurse coordinator
    Radiological evaluation in transplantation
    Monitoring and care
    Nutritional aspects of transplantation in adults
    Management of portal hypertensive hemorrhage
    Portopulmonary hypertension and hepatopulmonary syndrome
    Donor selection and management
    Extended criteria donors
    Donation after cardiac death
    The donor operation
    Principles of liver preservation
    Recipient hepatectomy and grafting
    Anesthesia for liver transplantation
    Imaging techniques for partial grafting
    Living donor transplantation in children
    Living donor transplantation : evaluation and selection in adults
    Adult living donor right hepatectomy and recipient operation
    Adult living donor left hepatectomy and recipient operation
    Split liver transplantation for pediatric and adult recipients
    Split liver transplantation for two adult recipients
    Biliary and vascular reconstruction in living donor transplantation
    Small-for-size syndrome
    Minimally invasive living donor hepatectomy
    Dual grafts for transplantation
    Outcomes of living donor transplantation : the Western perspective
    Outcomes of living donor transplantation : the Eastern perspective
    Ethics in living donor transplantation
    Arterial reconstruction : pitfalls
    Portal vein thrombosis and other venous anomalies
    Combined liver-kidney transplantation
    Retransplantation
    Clinical management of necrotic liver before and after transplantation
    Intestinal and multivisceral transplantation
    Transplantation : situs inversus and polysplenia syndrome
    Auxiliary transplantation
    Postoperative intensive care management in adults
    Postoperative intensive care management in children
    Postoperative management beyond the intensive care unit : adults
    Postoperative care of pediatric transplant recipients
    Transition of pediatric patients to adulthood
    Renal failure in adults
    Graft failure
    Technical problems : biliary
    Arterial complications after transplantation
    Infections after transplantation
    Recurrent hepatitis C after transplantation
    Late complications and recurrence of disease after transplantation
    Neuropsychiatric complications
    Neurological complications
    Role of the posttransplant clinical nurse coordinator
    Histopathology of liver transplantation
    Pathology of nonneoplastic disease after transplantation
    Transplant-related malignancies
    Rejection after transplantation
    Leukocyte chimerism: meaning and consequences
    ABO, tissue typing, and crossmatch incompatibility
    Graft-versus-host disease
    Induction and maintenance of immunosuppression
    Special considerations for immunosuppression in children
    Treatment of acute and chronic rejection
    Novel immunosuppression in patients with hepatic malignancies
    Novel immunosuppressive drugs
    Immunosuppressive biologic agents
    Long-term toxicity of immunosuppressive therapy
    Outcome predictors in transplantation
    U.S. trends in transplantation
    Long-term functional recovery and quality of life
    Survival and quality of life in children
    Genetic and genomic potential in liver transplantation
    Liver and hepatocyte xenotransplantation
    Stem cells and liver regeneration
    Ischemia-reperfusion injury in liver transplantation
    Extracorporeal perfusion for resuscitation of marginal grafts
    Current clinical status of extracorporeal devices.
    Digital Access ClinicalKey 2015
  • Digital
    Gabriel C. Oniscu, John L.R. Forsythe, Elizabeth A. Pomfret, editors.
    Summary: This book describes transplantation surgery techniques, the rationale behind the technique, the possible complications and ways to deal with them. Each chapter is written by an internationally known author, with explanatory text and medical illustrations.

    Contents:
    Insertion of Central Venous Catheters for Haemodealysis
    Creation of Endogenous Arteriovenous Fistulae and Arteriovenous Communication by using Endogenous and Sythetic Grafts
    Peritoneal Dialysis
    Abdominal Multi-Organ Retrieval from Heart Beating Cadaveric Donor
    Abdominal Multi-Organ Retrieval from Non Heart Beating Cadaveric Donor
    Thoracic Multi-Organ Retrieval from Heart and Non-Heart Beating Cadaveric Donor
    Organ Preservation
    Heart Transplantation
    Lung Transplantation
    Kidney Transplantation
    Pancreas Transplantation
    Interventional Radiological Techniques in Kidney and Pancreas Transplantation
    Liver Transplantation
    Small Bowel Transplantation
    Index.
    Digital Access Springer 2019
  • Digital
    Nadey Hakim, Mehmet Haberal, Daniel Maluf, editors.
    Contents:
    Intro
    Foreword
    Foreword
    Contents
    1: Organ Transplantation: A Historical Perspective
    1.1 Introduction
    1.2 Early History of Organ Transplantation
    1.3 The Science of Immunology
    1.4 The Beginning of the Modern Era of Kidney Transplantation
    1.5 Renal Transplantation Between Identical Twins
    1.6 Developments in Transplant Immunology
    1.7 Towards Success in the Clinic
    1.8 Other Early Immunosuppression Strategies: Anti-Lymphocyte Antibody Therapy
    1.9 Histocompatibility Antigens, the Development of Tissue Typing, and the Advent of Organ Sharing 1.10 Advances in Organ Preservation
    1.11 Early Attempts at Heart Transplantation
    1.12 Brain Death
    1.13 The First Attempts at Lung and Heart-Lung Transplantation
    1.14 Early Attempts at Transplantation of the Liver
    1.15 Early Attempts at Pancreas Transplantation
    1.16 Modern Immuno suppression: Calcineurin Inhibitors
    1.17 The Modern Era of Organ Transplantation
    1.18 New Plastic Transplants
    1.19 Xenotransplantation and Future Directions
    1.20 Conclusion
    1.21 Questions
    References 2: Tissue Typing, Crossmatching and the Allocation of Deceased Donor Kidney Transplants
    2.1 Introduction
    2.1.1 Tissue Typing
    2.1.1.1 Serological Tissue Typing
    2.1.2 Molecular Tissue Typing
    2.2 Epitopes
    2.2.1 Crossmatching
    2.2.1.1 The CDC Crossmatch
    2.2.1.2 The Flow Crossmatch
    2.2.1.3 The Virtual Crossmatch
    2.2.1.4 Clinical Uses of Crossmatching
    Assessing the Degree of HLA Sensitisation: Panel Reactive Antibodies
    Determining the Immunological Risk of a Transplant Pairing
    2.2.1.5 Cellular Crossmatching 2.2.2 Allocation of Deceased Donor Kidneys for Transplantation
    2.2.2.1 Principles of Allocation: Equity and Fairness Versus Utility
    2.3 Utility
    2.3.1 Longevity Matching
    2.3.1.1 Facilitating "Young to Young" and Avoiding "Young to Old"
    2.3.1.2 Facilitating "Old to Old"
    2.3.1.3 Kidney Donor Profile Index (KDPI) and Estimated Post-Transplant Survival (EPTS)
    2.3.2 HLA Matching
    2.4 Equity and Fairness
    2.4.1 Waiting Time
    2.4.2 Sensitisation
    2.4.3 Prior Living Kidney Donors
    2.4.4 Blood Group
    2.5 Medical Urgency and Needs
    2.5.1 Inadequate Dialysis 2.5.2 Paediatric Bonus
    2.5.3 Changes to the Kidney Allocation System (KAS) in the United States
    References
    3: The Immunobiology of Transplant Rejection and Acceptance
    3.1 Introduction
    3.1.1 Immune Response to Transplanted Tissue
    3.2 The Innate Immune System
    3.3 Role of Innate Immune System in Allograft Rejection
    3.4 The Adaptive Immune System
    3.4.1 Cells of the Adaptive Immune System
    3.4.1.1 T Cells
    3.4.1.2 Helper T Cells
    3.4.1.3 Type 1 Helper Cells
    3.4.1.4 Type 2 Helper Cells
    3.4.1.5 Cytotoxic T Cells
    3.4.1.6 T Regulatory Cells
    3.4.2 Role of Tregs in Experimental Allograft Tolerance.
    Digital Access Springer 2021
  • Digital
    edited by Gerhard F. Ecker, Rasmus P. Clausen, and Harald H. Sitte.
    Contents:
    Insights into transporter classifications: an outline of transporters as drug targets / Michael Viereck, Anna Gaulton, and Daniela Digles
    New trends in antidepressant drug research / Benny Bang-Andersen, Klaus P. Bøgesø, Jan Kehler, and Connie Sánchez
    The molecular basis of the interaction between drugs and neurotransmitter transporters / Harald H. Sitte, Thomas Stockner, and Michael Freissmuth
    γ-aminobutyric acid and glycine neurotransmitter transporters / Petrine Wellendorph, Julie Jacobsen, Jonas Skovgaard-Petersen, Andreas Jurik, Stine B. Vogensen, Gerhard Ecker, Arne Schousboe, Povl Krogsgaard-Larsen, and Rasmus P. Clausen
    ABC transporters: from targets to antitargets and back / Gerhard F. Ecker
    ABC transporters involved in cholestasis / Frans J.C. Cuperus, Julien Gautherot, Emina Halilbasic, Thierry Claudel, and Michael Trauner
    Recent advances in structural modeling of ABC transporters / Dennis Haake, Peter Chiba, and Gerhard F. Ecker
    PET imaging of ABC transporters at the blood-brain barrier / Oliver Langer
    The systems biology of transporters: targeting the regulatory system for transporters (FXR/RXR)
    ANO1 as a novel drug target / Anke Bill and Larry Alex Gaither
    Ligand discovery for the nutrient transporters ASCT2 and LAT-1 from homology modeling and virtual screening / Claire Colas and Avner Schlessinger
    Organic anion transporting polypeptides as drug targets / Eleni Kotsampasakou and Gerhard F. Ecker.
    Digital Access Wiley 2017
  • Digital
    Aaron M. Fischman, Rahul S. Patel, Robert A. Lookstein, editors.
    Summary: This book provides how-to recommendations and detailed guides for using transradial access in interventional radiology. A relatively new and growing technique, transradial access is most commonly found within interventional cardiology. This book approaches those cardiac uses of transradial access while extending its use to other body sites and disease states. The book details the interventional radiologist's transition to using transradial access across a broad spectrum of clinical applications, allowing them to better introduce it into their practice and to their patients. The text is divided into three sections: overview, clinical applications, and novel applications and techniques. The first section covers the history of transradial access, the initial patient assessment, and how to prepare for a procedure. The second section is divided into different diseases and interventional situations where transradial access could be considered, including subclavian artery stenosis and endovascular neurosurgery. The third section includes coverage of how to perform the latest techniques and projections for future procedures. This guide provides a manual of operations to assist in the setup of the practice, from office visit to procedure room to recovery across a variety of service lines and patient populations. Key take home points and equipment summaries accompany each chapter, allowing the user to easily navigate the book to accelerate his or her practice. This is an ideal guide for interventional radiologists. .

    Contents:
    SECTION I: Overview
    History
    Physical Exam and Assessment
    Nursing Assessment
    Procedure Suite Set-Up
    Recovery Room Implications
    SECTION II: Clinical Applications
    Renal and Mesenteric Artery Disease
    Interventional Oncology
    Peripheral Arterial Disease (Aorto-Iliac)
    Subclavian Artery Stenosis
    Pelvic Embolization
    Hemodialysis Access Interventions
    Carotid and Vertebral Interventions
    Endovascular Neurosurgery
    Acute Hemorrhage and Trauma
    SECTION III: Novel Applications and Techniques
    Ulnar Artery Access
    Distal Radial Artery Access
    Bariatric Embolization
    Infrainguinal Endovascular Therapy.
    Digital Access Springer 2022
  • Digital
    Yujie Zhou, Ferdinand Kiemeneij, Shigeru Saito, Wei Liu, editors.
    Digital Access Springer 2017
  • Digital
    Edward R. Laws, Jr., Aaron A. Cohen-Gadol, Theodore H. Schwartz, Jason P. Sheehan, editors.
    Digital Access Springer 2017

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Derived from Current Medical Diagnosis & Treatment, AccessMedicine's Quick Medical Diagnosis & Treatment provides topic reviews with key diagnostic and treatment features for more than 500 diseases.

A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.

Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.

MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available. DynaMed is a clinical information resource used to answer questions quickly at the point-of-care. Easy-to-interpret Levels of Evidence help clinicians rapidly determine the quality of the available evidence.

Biomedical and pharmacological abstracting and indexing database of published literature, by Elsevier. Embase® contains over 32 million records from over 8,500 currently published journals (1947-present) and is noteworthy for its extensive coverage of the international pharmaceutical and alternative/complementary medicine literature.

Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings. A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS. Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature. A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialties. Provides critical assessments of systematic reviews compiled from a variety of medical journals. Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.

Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences.

Includes cited reference searching, citation maps, and an analyze tool.

Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not.

Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.

Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations. PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians. Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration. Provides drug information targeted for patients. A continually updating drug monograph. ECRI Guidelines Trust: A comprehensive database of evidence-based clinical practice guidelines and related documents. MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or products LPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staff Micromedex Lab Advisor: Evidence based laboratory test information Provides patient handouts from the American Academy of Family Physician.

Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities.

In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.

A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.

A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.

Over 10,000 notes outline the status of specific infections within each country.

Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users. Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals. Contains full text access to selected biomedical and nursing books.

Provides online, full-text access to Springer's journal titles as well as journals from other publishers.

Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.

Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present. A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.