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all 850 "T" titles

T

  • 2007 Springer
    D.B. Moody (ed.).
    Also available: Print – 2007
  • 2009 Springer Protocols
    edited by Gennaro De Libero.
    Analysis of frequency and phenotype of antigen-specific T cells / Angus Stock and Vincenzo Cerundolo -- B cell helper assays / Sergio Abrignani, ... [et al.] -- Transkingdom RNA interference (tkRNAi) / Thu A. Nguyen and Johannes H. Fruehauf -- Flow cytometry and cell activation / Sonia Gavasso -- Investigating T cells by polychromatic flow cytometry / Enrico Lugli, Leonarda Troiano, and Andrea Cossarizza -- Generation of human T cell clones / Sabrina Mariotti and Roberto Nisini -- Limiting dilution analysis of antigen-specific T cells / Jorge Carneiro, Lurdes Duarte, and Elisabetta Padovan -- T cell epitope-mapping by cytokine gene expression assay / Maurizio Provengano and Giulio C. Spagnoli -- Cytokine multiplex immunoassay / Wilco de Jager, Berent Prakken, and Ger T. Rijkers -- Purification of the T cell antigen receptor and analysis by blue-native PAGE / Mahima Swamy and Wolfgang W.A. Schamel -- Non-replicating recombinant vaccinia virus expressing CD80 to enhance T-cell stimulation / Paul Zajac.
  • 2008 Karger
    volume editor, Kurt Blaser.
    Also available: Print – 2008
  • 2007
    Annette Langer-Gould.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer
    Bing Sun, editor.
    Overview of orchestration of CD4+ T cell subsets in immune responses -- Th1/Th2 cell differentiation and molecular signals -- Th1/Th2 cell?s function in immune system -- Regulatory T Cell differentiation and their function in immune regulation -- Th17 differentiation and their pro-inflammation function -- Tfh Cell differentiation and their function in promoting B cell responses -- Differentiation, Regulation and Function of Th9 Cell -- The biology and functions of Th22 cell.
    Also available: Print – 2014
  • 2014 Springer
    Stefan F. Martin, editor.
    This book summarizes the state-of-the art in the development of T cell-based in vitro assays, which offer useful tools for hazard identification, risk assessment and improvement of diagnostics. It will be of interest to scientists, the chemical and pharmaceutical industry, and regulators involved in the replacement of animal testing methods. The identification of hazardous chemicals and drugs is essential to ensuring human health. The ban on animal testing for the cosmetics industry since 2009 and international efforts to reduce and replace animal testing in research and immunotoxicology call for alternative in vitro methods. The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response. Therefore the use of T cells as tools for identifying contact allergens and drugs that may cause health problems is of great interest.
  • Google Books
    Bresler, Johannes.
    I. Geistes-, Nerven-, Augen-, Ohren-, Herz- und Gefässerkrankungen sowie Verdauungsstörungen infolge Tabakmissbrauchs -- II. Der Tabak in gewerbehygienischer Bezichung.
    Also available: Print – v. 1, 1911-13.
  • 2014 ClinicalKey
    [edited by] John A. Herring.
    Continuing the tradition of excellence that began in 1972, this latest edition of Tachdjian's Pediatric Orthopaedics offers the detailed visual guidance and unmatched expertise you need to effectively diagnose and treat pediatric musculoskeletal disorders. Extensive updates offer you the latest knowledge on etiology, imaging, differential diagnosis, and non-operative and surgical techniques for a wide range of pediatric orthopaedic conditions. Access expert guidance on difficult diagnostic and clinical management issues for your most challenging cases. Perfect your technique with the visual guidance of nearly 2,500 full-color illustrations and 60 videos of pediatric surgical procedures, including a number that highlight clinical examination and unusual clinical findings.
  • v. 1-3, 2008.
    [edited by] John Anthony Herring.
    Status: Not Checked OutLane Catalog Record
  • 2017 ClinicalKey
    [edited by] John A. Herring.
  • 2008 Karger
    volume editor, Youlian Hong.
    Temporal characteristics of foot movement in tai chi exercise / Hong, Y., Mao, D.W., Lia, J.X. -- The exercise intensity of tai chi chuan / Lan, C., Chen, S.-Y., Lai, J.-S. -- Tai chi exercise and muscle strength and endurance in older people / Xu, D.Q., Hong, Y., Li, J.X. -- Muscle action pattern and knee extensor strength of older tai chi exercisers / Wu, G. -- The effectiveness of tai chi exercise in improving aerobic capacity : an updated meta-analysis / Taylor-Piliae, R.E. -- Tai chi exercise in improving cardiorespiratory capacity / Thornton, E.W. -- Effects of a traditional taiji/qigong curriculum on older adults' immune response to influenza vaccine / Yang, Y. ... [et al.] -- Tai chi exercise and proprioception behavior in old people / Li; J.X., Xu, D.Q., Hong, Y. -- Neural mechanisms underlying balance control in tai chi / Gatts, S. -- Sensorimotor control of balance : a tai chi solution for balance disorders in older subjects / Tsang, W.W.N., Hui-Chan, C.W.Y -- Tai chi and balance control / Wong, A.M.K., Lan, C. -- Tai chi and falls prevention in older people / Harmer, P.A., Li, F. -- Tai chi exercise and the improvement of mental and physical health among college students / Wang, Y.T. -- Effect of tai chi on depressive symptoms amongst Chinese older patients with major depression : the role of social support / Chou, K.-L. -- Tai chi exercise and the improvement of health and well-being in older adults / Yau, M.K.-s. -- Teaching tai chi with mindfulness-based stress reduction to middle school children in the inner-city : a review of the literature and approaches / Wall, R.B. -- Tai chi chuan in the management of Parkinson's disease and Alzheimer's disease / Klein, P.J. -- Tai chi training for patients with coronary heart disease / Lan, C. ... [et al.] -- Tai chi exercise in patients with chronic heart failure / Yeh, G.Y., Wayne, P.M., Phillips, R.S. -- Tai chi chuan for breast cancer survivors / Mustian, K.M., Palesh, O.G., Flecksteiner, S.A. -- Tai chi improves pain and functional status in adults with rheumatoid arthritis : results of a pilot single-blinded randomized controlled trial / Wang, C. -- Effects of tai chi exercise on patients with type 2 diabetes / Wang, J.H.
    Also available: Print – 2008
  • 2006 CRCnetBASE
    Thomas S.C. Li.
  • 2011
    Melanie Watkins.
    Status: Not Checked OutLane Catalog Record
  • 2008 Springer
    Erica Sadun.
    A guide to the iPhone discusses the features of the device, including the iPhone media and the QWERTY keyboard, as well as its e-mail, voicemail, and calendar functions; Internet connectivity and applications; third-party software to enhance the iPhone; iTunes, iBooks, and iPhone games; power user applications; and accessories
  • 2014 Springer
    C. Niek van Dijk, John G. Kennedy, editors.
  • 2015 Springer Protocols
    edited by Ralf Kühn, Wolfgang Wurst, Benedikt Wefers.
    Xanthomonas and the TAL effectors: nature's molecular biologist -- TAL effector DNA-binding principles and specificity -- The development of TALE nucleases for biotechnology -- Online tools for TALEN design -- Assembly of customized TAL effectors through advanced ultimate system -- Engineering customized TALENs using the platinum gate TALEN kit -- Design, assembly, and characterization of TALE-based transcriptional activators and repressors -- A new approach to dissect nuclear organization: TALE-mediated genome visualization (TGV) -- TALEN-induced translocations in human cells -- Mutagenesis in newts: Protocol for Iberian ribbed newts -- Targeted mutagenesis in Bombyx mori using TALENs -- Geneknockout by targeted mutagenesis in a hemimetabolous insect, the two-spotted cricket Gryllus bimaculatus, using TALENs -- Methods for talen evaluation, use, and mutation detection in the mosquito Aedes aegypti -- Methods for TALEN-mediated genomic manipulations in drosophila -- Targeted mutagenesis in zebrafish by TALENs -- Mutagenesis in xenopus and zebrafish using TALENs -- Genome editing in mice using TALE nucleases -- Genome editing in rats using tale nucleases -- Designer nuclease-mediated generation of knockout THP1 cells.
  • Geoff Colvin.
    Status: Not Checked OutLane Catalog Record
  • 2006 ebrary
    Gillian White.
    Introduction : Finding a voice for the spirit -- Spirituality and the holistic approach -- Learning about spirituality in the multi-professional team -- Developing opportunities to talk about spirituality -- Understanding spirituality -- Spiritual care -- Outcomes and opportunities -- Conclusion : the journey continues.
  • 2008
    Lenore M. Buckley ; foreword by Arthur W. Frank.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    Philipp Y. Maximov, Russell E. McDaniel, V. Craig Jordan.
    Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the "father of tamoxifen" - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a "failed morning after contraceptive" to become the "gold standard" for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen's pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.
  • 2012
    edited by Anthony J. Hannan.
    Tandem repeat polymorphisms : mediators of genetic plasticity, modulators of biological diversity and dynamic sources of disease susceptibility / Anthony J. Hannan -- Evolution of simple sequence repeats as mutable sites / David G. King -- Single amino acid and trinucleotide repeats : function and evolution / Noel Faux -- Promoter microsatellites as modulators of human gene expression / Sterling M. Sawaya ... [et al.] -- Dynamic mutations : where are they now? / Clare L. Van Eyk and Robert I. Richards -- Unstable mutations in the FMR1 gene and the phenotypes / Danuta Loesch and Randi Hagerman -- Molecular pathways to polyglutamine aggregation / Amy L. Robertson and Stephen P. Bottomley -- Polyglutamine aggregation in Huntington and related diseases / Saskia Polling, Andrew F. Hill and Danny M. Hatters -- Selective neurodegeneration, neuropathology and symptom profiles in Huntington's disease / Henry J. Waldvogel ... [et al.] -- Kennedy's disease : clinical significance of tandem repeats in the androgen receptor / Jeffrey D. Zajac and Mark Ng Tang Fui -- Characterising the neuropathology and neurobehavioural phenotype in Friedreich ataxia : a systematic review / Louise A. Corben ... [et al.] -- Polyalanine tract disorders and neurocognitive phenotypes / Cheryl Shoubridge and Jozef Gecz.
  • 2013 Springer Protocols
    edited by Danny M. Hatters, Anthony J. Hannan.
    Longitudinal imaging and analysis of neurons expressing polyglutamine-expanded proteins / Andrey S. Tsvetkov, D. Michael Ando, and Steven Finkbeiner -- Atomic force microscopy assays for evaluating polyglutamine aggregation in solution and on surfaces / Kathleen A. Burke and Justin Legleiter -- Morphometric analysis of Huntington's disease neurodegeneration in Drosophila / Wan Song ... [et al.] -- Size analysis of polyglutamine protein aggregates using fluorescence detection in an analytical ultracentrifuge / Saskia Polling, Danny M. Hatters, and Yee-Foong Mok -- Method for the incremental expansion of polyglutamine repeats in recombinant proteins / Amy L. Robertson and Stephen P. Bottomley -- Pulse shape analysis (PulSA) to track protein translocalization in cells by flow cytometry : applications for polyglutamine aggregation / Yasmin M. Ramdzan, Rebecca Wood, and Danny M. Hatters -- Characterizing social behavior in genetically targeted mouse models of brain disorders / Emma L. Burrows and Anthony J. Hannan -- PCR amplification and sequence analysis of GC-rich sequences : aristaless-related homeobox example / May H. Tan, Jozef Gécz, and Cheryl Shoubridge -- Challenges of "Sticky" co-immunoprecipitation : polyalanine tract protein-protein interactions / T.R. Mattiske ... [et al.] -- Molecular pathology of polyalanine expansion disorders : new perspectives from mouse models / James N. Hughes and Paul Q. Thomas -- Yeast as a platform to explore polyglutamine toxicity and aggregation / Martin L. Duennwald -- Immuno-based detection assays to quantify distinct mutant huntingtin conformations in biological samples / Gregor P. Lotz and Andreas Weiss -- Modeling and analysis of repeat RNA toxicity in Drosophila / S.E. Samaraweera ... [et al.] -- Analyzing modifiers of protein aggregation in C. elegans by native agarose gel electrophoresis / Mats Holmberg and Ellen A.A. Nollen -- Kinetic analysis of aggregation data / Regina M. Murphy -- Bioinformatics method for identifying Q/N-rich prion-like domains in proteins / Eric D. Ross ... [et al.] -- Detecting soluble polyQ oligomers and investigating their impact on living cells using split-GFP / Patrick Lajoie and Erik Lee Snapp -- Cell biological approaches to investigate polyglutamine-expanded AR metabolism / Lori J. Cooper and Diane E. Merry.
  • Springer Protocols
    v. 2 Springer Protocols
    edited by Mouldy Sioud.
    v. 1. Emerging strategies for targets and biomarker discovery -- v. 2. Emerging molecular targets and treatment options.
  • 2013 Springer Protocols
    edited by Jürgen Moll, Riccardo Colombo.
    The path to oncology drug target validation : an industry perspective -- Identification of aptamers as specific binders and modulators of cell-surface receptor activity -- The design and structure-functional properties of DNA-based immunomodulatory sequences -- SiRNA design principles and off-target effects -- Western blot evaluation of siRNA delivery by ph-responsive peptides -- High-throughput RNAi screening for the identification of novel targets -- Integration of RNAi and small molecule screens to identify targets for drug development -- CellProfiler and KNIME : Open source tools for high content screening -- PARP inhibition as a prototype for synthetic lethal screens -- Structure-based target druggability assessment -- Validating pharmacological disruption of protein-protein interactions by acceptor photobleaching FRET imaging -- Systematic analysis of complex signal transduction pathways using protein fragment complementation assays -- Reverse phase protein microarrays and their utility in drug development -- A cell culture system that mimics chronic lymphocytic leukemia cells microenvironment for drug screening and characterization -- Two-dimensional vs. Three-dimensional in vitro tumor migration and invasion assays -- Tumor spheroid-based migration assays for evaluation of therapeutic agents -- The neurosphere assay applied to neural stem cells and cancer stem cells -- Genetically engineered animal models for in vivo target identification and validation in oncology -- Target validation in mice by constitutive and conditional RNAi -- In vivo target validation by inducible RNAi in human xenograft mouse models -- Bright-field in situ hybridization methods to discover gene amplifications and rearrangements in clinical samples -- Combined microRNA in situ hybridization and immunohistochemical detection of protein markers.
  • 2009 Springer
    edited by Uday Kishore.
    Macrophage pattern recognition receptors in immunity, homeostasis, and self tolerance / Subhankar Mukhopadhyay, Annette Plüddemann, and Siamon Gordon -- Pattern recognition by toll-like receptors / Stefan Bauer, Thomas Müller, and Svetlana Hamm -- Nod-like receptors : pivotal guardians of the immunological integrity of barrier organs / Philip Rosenstiel and Stefan Schreiber -- Toll-like receptors and nod-like receptors : domain architecture and cellular signalling / Tanja Langefeld ... [et al.] -- Humoral pattern recognition molecules : mannan-binding lectin and ficolins / Steffen Thiel and Mihaela Gadjeva -- Lung surfactant proteins A and D as pattern recognition proteins / Patrick Waters ... [et al.] -- Pattern recognition by pentraxins / Alok Agrawal ... [et al.] -- Target pattern recognition by complement proteins of the classical and alternative pathways / Yu-hoi Kang ... [et al.] -- Pattern recognition in phagocytic clearance of altered self / Yoshinobu Nakanishi, Peter M. Henson and Akiko Shiratsuchi -- Structural basis of pattern recognition by innate immune molecules / Eamon P. McGreal -- Lessons from the fly : pattern recognition in Drosophila melanogaster / Subhamoy Pal and Louisa P. Wu -- Immune recognition of plasmodium-infected erythrocytes / Damien V. Cordery and Britta C. Urban -- Innate immune recognition in tuberculosis infection / Anthony G. Tsolaki.
    Also available: Print – 2009
  • 2015 Springer
    Anca-Ligia Grosu, Carsten Nieder, editors.
    The main objective of this book is to provide radiation oncologists with a clear, up-to-date guide to tumor delineation and contouring of organs at risk. With this in mind, a detailed overview of recent advances in imaging for radiation treatment planning is presented. Novel concepts for target volume delineation are explained, taking into account the innovations in imaging technology. Special attention is paid to the role of the newer imaging modalities, such as positron emission tomography and diffusion and perfusion magnetic resonance imaging. All of the most important tumor entities treated with radiation therapy are covered in the book. Each chapter is devoted to a particular tumor type and has been written by a recognized expert in that topic.
  • 2013 Springer
    Nancy Y. Lee, Jiade J. Lu, editors.
    This handbook is designed to enable radiation oncologists to appropriately and confidently delineate tumor volumes/fields for conformal radiation therapy, including intensity-modulated radiation therapy (IMRT), in patients with commonly encountered cancers.The orientation of this handbook is entirely practical, in that the focus is on the illustration of clinical target volume (CTV) delineation for each major malignancy. Each chapter provides guidelines and concise knowledge on CTV selection for a particular disease, explains how the anatomy of lymphatic drainage shapes the selection of the target volume, and presents detailed illustrations of volumes, slice by slice, on planning CT images. While the emphasis is on target volume delineation for three-dimensional conformal therapy and IMRT, information is also provided on conventional radiation therapy field setup and planning for certain malignancies for which IMRT is not currently suitable.
  • 2015 Springer
    Nancy Y. Lee, Nadeem Riaz, Jiade J. Lu, editors.
    This textbook is designed to help the busy radiation oncologist to accurately and confidently delineate tumor volumes for conformal radiation therapy (including IMRT). The book provides an atlas of clinical target volumes (CTVs) for commonly encountered cancers, with each chapter illustrating CTV delineation on a slice-by-slice basis, on planning CT images. Common anatomic variants for each tumor are represented in individual illustrations, with annotations highlighting differences in coverage. The anatomy of each site and patterns of lymphatic drainage are discussed, and their influence on the design of CTVs is explained in detail. Utilization of other imaging modalities, including MRI, to delineate volumes is highlighted. Key details of simulation and planning are briefly reviewed. Although the emphasis is on target volume delineation for conformal techniques, information is also provided on conventional radiation field setup and design when IMRT is not suitable.
  • 2009 Springer
    Joseph Lustgarten, Yan Cui, Shulin Li, editors.
  • 2008 Springer
    edited by Razelle Kurzrock, Maurie Markman.
    Perspectives : bench to bedside and back / Jennifer Wheler and Razelle Kurzrock -- Targeted therapy in acute myelogenous leukemia / Elihu Estey -- Targeted therapy in breast cancer / Barbara S. Craft and Stacy Moulder -- Targeted therapy in chronic lymphocytic leukemia / Apostolia-Maria Tsimberidou and Michael J. Keating -- Targeted therapy in chronic myeloid leukemia / Elias Jabbour, Jorge Cortes, and Hagop Kantarjian -- Targeted therapy in colorectal cancer / Scott Kopetz -- Targeted therapy in non-small cell lung cancer / David J. Stewart -- Targeted therapy in lymphoma / Amanda Wedgwood and Anas Younes -- Targeted therapy in melanoma / Michael Davies, Sunil Patel, and Kevin B. Kim -- Targeted therapy in multiple myeloma / Yuhong Zhou, Raymond Alexanian, and Micael Wang -- Targeted therapy in myelodysplastic syndrome / Alfonso Quintás-Cardama ... [et al.] -- Targeted therapy in epithelial ovarian cancer / Maurie Markman -- Targeted drug therapy in pancreatic cancer / Don L. Gibbons, Robert A. Wolff, and Gauri Varadhachary -- Targeted therapy in prostate cancer / Amado J. Zurita, John F. Ward, and Jeri Kim -- Targeted therapy in renal cell carcinoma / Eric Jonasch and Nizar Tannir -- Targeted therapy of Sarcoma / Joseph Ludwig and Jonathan C. Trent -- Targeted and functional imaging / Vikas Kundra, Dawid Schellingerhout, and Edward F. Jackson -- Combining targeted therapies / David Hong and Lakshmi Chintala -- Drug development in cancer medicine : challenges for targeted approaches / Luis H. Camacho -- Toward personalized therapy for cancer / Sarah J. Welsh and Garth Powis.
  • 2010 CRCnetBASE
    edited by Ajit S. Narang, Ram I. Mahato.
    Therapeutic potential of targeted drug delivery / Ajit S. Narang and Ram I. Mahato -- Antibody therapies for liver malignancy and transplantation / John M. Luk and Kwong-Fai Wong -- Transferrin receptor-mediated transcytosis in intestinal epithelial cells for gastrointestinal absorption of protein drugs / Nurmamet Amet ... [et al.] -- Ionizing radiation for tumor targeted drug delivery / Roberto Diaz, Li Zhou, and Dennis E. Hallahan -- Recent advances in gene expression and delivery systems / Ravikiran Panakanti and Ram I. Mahato -- Cellular barriers for nucleic acid delivery and targeting / Arto Urtti -- Targeted delivery systems of non-viral nucleic acid-based therapeutics / Ga Yong Shim ... [et al.] -- Delivery and targeting of oligonucleotides and siRNA / Ningning Yang and Ram I. Mahato -- Liposomes for non-viral gene delivery / Jiasheng Tu ... [et al.] -- Delivering the bullet to the right intracellular target : a cellular perspective on drug delivery / Maria Teresa Tarragâo-Trani and Brian Storrie -- Mitochondria-targeted drug delivery / Volkmar Weissig and Gerard G. M. D'Souza -- Site-specific prodrug activation strategies for targeted drug action / Mark D. Erion -- Enzyme-activated prodrug strategies for targeted drug action / Jarkko Rautio ... [et al.] -- Targeting colon and kidney : pathophysiological determinants of design strategy / Ajit S. Narang and Ram I. Mahato -- Principles and practice of pulmonary drug delivery / Vivek Gupta, Chandan Thomas, and Fakhrul Ahsan -- Recent advances in ocular drug delivery : role of transporters, receptors, and nanocarriers / Gyan P. Mishra ... [et al.] -- Injectable polymers for regional drug delivery / Rajendra P. Pawar ... [et al.] -- Polymer-drug conjugates / Lucienne Juillerat-Jeanneret and Feride Cengelli -- Polymer micelles for drug delivery / Sungwon Kim and Kinam Park -- Multifunctional stimuli-responsive nanoparticles for targeted delivery of small and macromolecular therapeutics / Srinivas Ganta, Arun Iyer, and Mansoor Amiji -- Physiological stress responsive gene regulation systems for tissue targeting / Hyun Ah Kim and Minhyung Lee.
  • 2011 Springer
    Ann L. Jackman, Christopher Leamon, editors.
  • 2007 Springer
    B. Groner, ed.
    Introduction: the rationale for the development of targeted drugs in cancer therapy -- Identifying critical signaling molecules for the treatment of cancer -- Tyrosine kinase inhibitors and cancer therapy -- Targeting ERBB receptors in cancer -- Inhibition of the IGF-I receptor for treatment of cancer. Kinase inhibitors and monoclonal anitbodies as alternative approaches -- Inhibition of the TGF-B signaling pathway in tumor cells -- The mammalian target of rapamycin kinase and tumor growth inhibtition -- The ras signalling pathway as a target in cancer therapy -- The mitogen-activated protein kinase pathway for molecular-targeted cancer treatment -- Clinical relevance of tareted interference with Src-mediated signal transduction events.
    Also available: Print – 2007
  • 2014 Springer
    Mohammed Keshtgar, Katharine Pigott, Frederik Wenz, editors.
    Targeted intraoperative radiotherapy is a major advance in the management of cancer patients and has been attracting massive interest worldwide following publication of the results of an important randomized controlled trial in The Lancet. This textbook is designed to introduce this innovative technology in a comprehensive manner to clinicians dealing with cancer patients. Throughout, the emphasis is on practical aspects, and the text is supported by many excellent illustrations. The editors of the book have extensive experience in targeted intraoperative radiotherapy and include co-directors of the TARGIT Academy, which runs international training courses on the technology in the United Kingdom and Germany. They have brought together multidisciplinary contributors from different centers across the world who have wide experience in the field and whose work has been recognized internationally. It is the editors' hope that this book will succeed in ensuring that targeted intraoperative radiotherapy is used effectively worldwide.
  • 2012 CRCnetBASE
    edited by Michael J. Welch, William C. Eckelman.
    "Covering the fundamental concepts of molecular imaging, this work addresses basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery. Topics are presented in logical progression, from basic concepts to applications. The text includes examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases. The book is a valuable tool for readers involved with molecular imaging, biomedical imaging, radiology, medical physics, medicinal chemistry, and pharmacology"--Provided by publisher.
  • 2014 CRCnetBASE
    edited by Todd A. Kuiken, Aimee E. Schultz Feuser, Ann K. Barlow.
    "This reference covers clinical and bioengineering aspects of muscle reinnervation, a popular new technique at the boundary of biomedical and rehabilitation engineering and neuroscience. With contributions from pioneers in the field, the book provides a review of muscle reinnervation from a biomedical engineering and clinical perspective. It describes neuroscience and other related neuroprosthetic techniques. A companion website offers a wide range of videos and multimedia material to aid in comprehension and application"--Provided by publisher.
  • 2011 Springer
    Daniel Gioeli, editor.
    Resistance to Targeted Therapies As a Result of Mutation(s) in the Target / Alexis B. Cortot and Pasi A. Jänne -- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies / Daniel Gioeli -- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry / Jason R. Neil and Forest M. White -- Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications / Julia D. Wulfkuhle, Menawar Khalil, Joseph C. Watson, Lance A. Liotta and Emanuel F. Petricoin -- Using Phosphoflow® to Study Signaling Events of Subpopulations Resistant to Current Therapies / Omar D. Perez -- Mathematical and Computational Models in Cancer / Sudhir Chowbina, Kevin A. Janes, Shayn M. Peirce and Jason A. Papin -- Somatic Evolution of Acquired Drug Resistance in Cancer / John W. Pepper -- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer / Edward Gunther -- microRNA: A Potential Therapy Able to Target Multiple Cancer Pathways / Benjamin Kefas and Benjamin W. Purow -- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance / Yun Dai and Steven Grant.
  • 2011 Future Med
    editor, Luigi Bolondi.
    Targeted therapies for hepatocellular carcinoma / Luigi Bolondi -- Overview of HCC pathophysiology and drug targets / Liliana Montella & Raffaele Addeo -- Antiangiogenic strategies for the treatment of hepatocellular carcinoma / Chiun Hsu, Ying-Chun Shen & Ann-Lii Cheng -- EGF receptor inhibitors for hepatocellular carcinoma / George Papatsimbas, Christina Chatedaki & Dimitris Zacharoulis -- mTOR inhibitors / Gerhard Treiber & Thomas Wex -- Histone deacetylase inhibitors (epigenetic alterations) / Sergio Valente & Antonello Mai -- Hepatocellular carcinoma therapy : combination is the future / Jean-François Dufour -- Other new targeted therapies / Jairo A. Garcia & Lewis R. Roberts.
  • 2012 Future Med
    editors, Arun Rajan, Giuseppe Giaccone.
    Targeted therapy for non-small-cell lung cancer / Arun Rajan & Giuseppe Giaccone -- Overview of pathophysiology and drug targets for non-small-cell lung cancer / Anish Thomas, Arun Rajan & Giuseppe Giaccone -- EGFR inhibitors and their use in the treatment of metastatic disease / Cesare Gridelli & Antonio Rossi -- VEGF receptor inhibitors / Ariel Lopez-Chavez & Alan Sandler -- CTLA-4 inhibitor : ipilimumab for the treatment of NSCLC / Julie R. Brahmer -- VEGF receptor inhibitors / Kavitha Ramchandran, Millie Das & Heather Wakelee -- HGFR/MET and ALK inhibitors / Eunice L. Kwak -- Vaccines for lung cancer / Ronan J. Kelly -- Index.
  • 2011 Future Med
    editor, Ronald M. Bukowski.
    Targeted therapy for renal cell carcinoma / Ronald M. Bukowski -- Overview of renal cell carcinoma pathways and drug targets / Bernard Escudier -- mTOR in renal cell cancer: modulator of tumor biology and therapeutic target / Piotr J. Wysocki -- VEGF inhibitors / Toni K. Choueiri & Ali R. Golshayan -- VEGFR/PDGFR inhibitors in RCC / Jean S.Z. Lee & Tim Eisen -- Next-generation immunotherapy: CTLA-4 and PD-1 inhibitors / Daniel Y.C. Heng -- EGF receptor inhibitors / Marine Gross-Goupil & Alain Ravaud -- Cytokines / Alexandra Leary, James M.G. Larkin & Lisa M. Pickering -- Vaccination / Robert J Amato -- Evidence-based therapy of non-clear-cell and sarcomatoid renal cell carcinoma / Elan Diamond, Naveed H. Akhtar, Scott T. Tagawa & David M. Nanus -- Bisphosphonates in renal cell carcinoma: palliation versus antitumor effects / Saby George & Roberto Pili -- Combination therapy and future directions in renal cell carcinoma / Bernard Escudier & Camillo Porta.
  • 2015 Springer
    Antonio Russo, Rafael Rosell, Christian Rolfo, editors.
    This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.
  • 2007 Springer
    Manfred Dietel (ed.)
    Also available: Print – 2007
  • 2008 Springer
    Francesco Colotta, Alberto Mantovani, editors.
    Also available: Print – 2008
  • 2015 Springer
    Michael Andreeff, editor.
    This book provides an unprecedented overview of targeted therapies for acute myeloid leukemias. The volume provides comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Authoritative chapters are written by leading research scientists and clinicians, who explain basic concepts and the clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML. The chapter topics include the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53, and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. In addition, chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells, and leukemia metabolism, provide insight into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies complete the overview of the multi-dimensional therapeutic landscape, where leukemia specialists develop treatment strategies, which are expected to bring forth critical breakthroughs in the field of leukemia.
  • 2010 ClinicalKey
    [edited by] Michael H. Weisman [and others].
    Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients. Chapters cover the full breadth of rheumatic diseases, rheumatoid arthritis, lupus, connective tissue diseases, osteoporosis, regional pain disorders, and fibromyalgia. The full-color design presents detailed clinical photographs and treatment algorithms for visual guidance and easy reference. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use. Displays the clinical manifestations of rheumatic diseases in full color, along with treatment algorithms for easy at-a-glance reference.
  • OHR
  • 2011
    Mandy Miller Koop.
    Hypokinesia is one of the most disabling movement abnormalities caused by Parkinson's disease (PD). It is a clinical term that refers to the general reduction of mobility experienced by people with Parkinson's disease (PWPD). Hypokinesia affects movements in three ways: 1) movements are slow 2) movements are performed with reduced amplitude compared to what is required for the task and 3) it takes longer for PWPD to initiate movements. All of these impairments affect the ability of PWPD to perform common daily activities and can cause feelings of frustration and anger that may lead to altered self esteem, depression, and a reduction in their quality of life. Although effective treatments do exist for well-selected patients, there are many avenues open for improving current treatments, identifying new treatments, and understanding mechanisms of hypokinesia that could potentially lead to more effective therapies and greatly impact the lives of PWPD. In this dissertation we sought to improve current treatments and provide opportunities for future treatments for hypokinesia by addressing three important clinical questions relating to hypokinesia. First, are there immediate improvements in hypokinesia from a surgical procedure called deep brain stimulation (DBS) that can be measured during surgery and used to help guide surgical decisions and optimize clinical outcomes? Second, can we determine what types of movements are affected by hypokinesia in early stage, untreated PD in order to provide an objective metric used to assess an emerging treatment for PD? Third, might perceptual deficits that are linked to sensory processing impairments play a role in the manifestation of hypokinesia? If so, targeting these deficits may provide new and better therapies. We addressed these questions by using the quantitative and computational techniques outlined in the next three paragraphs. A common treatment for advanced PD is a surgical procedure called DBS. The surgery is performed on awake patients, and it entails surgically implanting electrodes (leads) that provide chronic stimulation to the affected brain area that controls movement. Although the treatment is almost always effective, the degree of improvement in hypokinesia varies among patients. The accuracy of the placement of the DBS lead in the affected area is believed to have the most effect on the improvement of hypokinesia. We suggest that using quantitative measurements of hypokinesia to evaluate the efficacy of the location of the DBS lead in improving hypokinesia during the surgical procedure might therefore improve the overall clinical outcomes. The surgical team would then have objective, accurate measurements of the degree of improvement in hypokinesia during the surgery, when the lead's position in the brain could be modified to achieve optimal results. Therefore, we designed a prospective study to measure upper extremity hypokinesia using a quantitative measure of angular velocity. Analysis of 98 DBS procedures performed on 61 patients showed that on average there was an 81% improvement in quantitative measures of hypokinesia from implanting and activating the DBS lead (p< 0.03). This study demonstrated that objective, high-resolution, accurate measurements of improvements in hypokinesia from intra-operative DBS are possible in this highly constrained environment and could therefore be used to help guide surgical decisions and optimize clinical outcomes. PD has no cure, but treatments in the near future may include disease-slowing medications. Although few studies have characterized the motor control abnormalities of very early stage PD, when symptoms are mild and usually unilateral, this group is the most targeted for potential disease-modifying therapeutics. In this study, we asked if quantitative measures of finger, limb, and postural movement velocity could detect hypokinesia in 20 patients with very early stage, untreated PD. The results revealed evidence of significant finger and limb hypokinesia of the patient group's more affected side when compared to the non-dominant side of 19 age-matched healthy adults (HAs) (p=0.001 and p< 0.001, respectively). Furthermore, the patient group's limb movement velocity on the more affected side was significantly slower than their less affected side (p=0.005), highlighting the importance of using an outcome measure that is lateralized in studies of very early stage PD. In contrast to our previous study that revealed significant postural hypokinesia in patients with advanced PD, we did not detect postural hypokinesia in patients with very early stage, untreated PD. Based on these findings, we suggest that the use of quantitative lateralized measures of hypokinesia would be useful in neuroprotective clinical studies of very early stage, untreated PD and may improve the chances of detecting a disease-modifying effect of potential neuroprotective therapeutics. Detecting such a therapy would have a large impact by improving the lives of PWPD. Although hypokinesia is considered a movement abnormality, new research is suggesting that perceptual deficits may play a role in the manifestation of abnormal movements in PWPD. Motor control theory posits that a sensorimotor integration process (SIP) is used by the central nervous system to perceive and control movement by combining internally generated predictions of movement parameters with the processing of sensory feedback. A previous study examining the SIP demonstrated that HAs overestimated their limb position in the direction of movement, and that the error and its variance (VOE) depended on movement duration. Using quantitative measures of hypokinesia, we asked if PWPD showed errors in perceived limb position and if the dependence on movement duration was different from HAs. We used an established computational model of the SIP to explore mechanisms for the error and VOE as a function of movement duration. Twenty PWPD, off medication, and 20 age-matched HAs were asked to estimate the position of their hand after performing 50, slow, non-visually guided wrist flexion or extension movements for a random period of time (< 4.0 sec). Both groups overestimated the amount they moved; however, the PWPD's error and VOE were larger (p< 0.001). More specifically, HAs exhibited increasing error/VOE for small movement durations that reduced/stabilized for longer movement durations. PWPD, however, showed increasing error/VOE with increasing movement duration that did not significantly improve/stabilize. The results from the model revealed an 88% increase in the variance (noise) in the sensory feedback parameter in PWPD compared to HAs, which suggests the PWPD's SIP could no longer effectively access sensory feedback information to correct errors in other components of the SIP due to the large amount of noise in this signal. This study provides experimental evidence that perceptual deficits may play a role in hypokinesia and computational evidence that abnormal processing of sensory feedback in PWPD's SIP could contribute to increased perceptual error in limb position after non-visually guided movements. The work in this dissertation quantified the immediate improvements in hypokinesia from intra-operative DBS, the presences of hypokinesia in early stage, untreated PD, and the degree of perceptual deficits and their dependency on movement duration in PD. Furthermore, this research has provided evidence for possible mechanisms for hypokinesia. Taken together, this work has the possibly to provide immediate improvements for current treatments and provides several platforms for future therapies to treat hypokinesia and improve the lives of PWPD.
  • 2012
    Elizabeth Josephine Beans.
    The theme of this work is to utilize hypothesis driven synthetic manipulation to enhance our understanding of the biological effects of prostratin and its highly potent analogs, and to utilize this understanding for the improvement of the therapeutic properties thereof. Prostratin, a natural product activator of protein kinase C (PKC), is a molecule of interest for targeting latent HIV, the primary obstacle to HIV eradication in infected individuals on effective highly active antiretroviral therapy. Chapter one describes the current state of the HIV pandemic, therapeutic strategies, prospects for a cure, and clinical studies toward immune activation therapy. Chapter two is a seminal and complete analysis of the biological effects of prostratin, a natural product candidate for immune activation therapy. Chapter three presents the design, synthesis, and evaluation of highly potent analogs of prostratin via an efficient semi-synthetic route. Chapter four presents the design and synthesis of isotopically labeled prostratin analogs to be utilized in solid-state NMR studies probing the active conformation of the PKC/activator complex in its membrane associated state. Chapter five presents the design, synthesis, and evaluation of prodrugs of prostratin and prostratin analogs for the optimization of pharmacologic properties.
  • 2007
    Patrick D. Sutphin.
    Status: Not Checked OutLane Catalog Record
  • 2001 HighWire
    edited by Alfonso Castro-Beiras and Gian Franco Gensini.
    Also available: Print – 2001
  • 2011 Springer
    Kathleen H. Goss, Michael Kahn, editors.
  • 2009 Springer
    Mark W. Kroll, Jeffrey D. Ho, editors.
    Conducted electrical weapons: a user's perspective / Greg Meyer -- The scientific history / Robert A. Stratbucker -- Conducted electrical weapons and resolution of use-of-force encounters / Charles Mesloh, Mark Henych, and Ross Wolf -- Nonlethal weapons: the broader context / Peter J. Cuenca and John G. McManus -- Transcutaneous muscle stimulation / James D. Sweeney -- Current flow in the human body / Dorin Panescu and Robert A. Stratbucker -- Animal studies / John G. Webster -- CEW research models: animal and human studies / Theodore C. Chan and Gary M. Vilke -- Cardiac arrhythmias / Derek J. Dosdall and Raymond E. Ideker -- Electrocardiographic effects of the CEW / Jeffrey D. Ho -- Serum and skin effects of CEW application / Jeffrey D. Ho -- Electrocardiographic effects of the CEW / Robert Reardon -- Rhabdomyolysis / Ronald Moscati and Samuel Cloud -- Effects of CEWs on respiration / Donald M. Dawes -- Neuroendocrine effects of CEWs / Donald M. Dawes and Mark W. Kroll -- Electroporation of cardiac and nerve cells / Vadim V. Fedorov, Leonid Livshitz, Geran Kostecki, and Igor R. Efimov -- Eye and head injuries / S. Robert Witherspoon, Andreas K. Lauer, and Jonathan L. Marinaro -- CEW effects with illegal stimulant intoxication / Patrick Tchou -- Alcohol and the CEW / Ronald Moscati and Jeffrey D. Ho -- Conducted electrical weapons and implantible cardiac devices / Subba Reddy Vanga, James L. Vacek. Loren Berenhom and Dhanunjaya R. Lakkireddy -- Risk management and the CEW / Greg Bingham -- The New York City experience / Michael D. White and Justin Ready -- Impact of CEW and other types of force and resistance on officer and suspect injuries / Michael R. Smith, Robert J. Kaminski, Jeffrey Rojek, Geoffrey P. Alpert, and James Mathis -- Field statistics overview / James E. Brewer and Mark W. Kroll -- Sudden in-custody death / Samuel J. Stratton -- Stimulant abuse and sudden cardiac death / Steven B. Karch -- The systemic role of illicit drugs and their toxicology / Joshua Gunn, Michael A. Evans, and M. Scott Kriger -- Excited delirium syndrome / Vincent J. M. Di Maio and Theresa G. Di Maio -- Biochemical brain markers in excited delirium deaths / Deborah C. Mash -- Sudden unexpected death in custody (SUDIC) / Charles V. Wetli -- Legal basics for the CEW -- Science and logic meet the law / Michael A. Brave -- Appendix A: Excited delirium checklist -- Appendix B: Electrocution diagnosis checklist.
  • 2006 Karger
    editors, Thomas Hummel, Antje Welge-Lüssen.
    Central gustatory processing in humans / Small, D.M. -- Modern psychophysics and the assessment of human oral sensation / Snyder, D.J., Prescott, J., Bartoshuk, L.M. -- Postoperative/posttraumatic gustatory dysfunction / Landis, B.N., Lacroix, J.-S. -- Neurological causes of taste disorders / Heckmann, J.G., Lang, C.J.G. -- Toxic effects on gustatory function / Reiter, E.R., DiNardo, L.J., Costanzo, R.M. -- Burning mouth syndrome / Grushka, M., Ching, V., Epstein, J. Nasal anatomy and the sense of smell / Hornung, D.E. -- Transduction and coding / Rawson, N.E., Yee, K.K. -- Smell: central olfactory processing / Gottfried, J.A. -- Structure and function of the vomeronasal organ / Witt, M., Wozniak, W. -- Assessment of olfactory function / Hummel, T., Welge-Lüssen, A. -- Posttraumatic olfactory loss / Costanzo, R.M.C., Miwa, T.M. -- Chronic rhinosinusitis and olfactory dysfunction / Raviv, J.R., Kern, R.C. -- Olfactory disorders following upper respiratory tract infections / Welge-Lüssen, A., Wolfensberger, M. -- Olfaction in neurodegenerative disorder / Hawkes, C. -- Human taste: peripheral anatomy, taste transduction, and coding / Breslin, P.A.S., Huang, L. --
    Also available: Print – 2006
  • 2015 Karger
    volume editors, Jørgen Serup, Nicolas Kluger, Wolfgang Bäumler.
    Preface -- The tattooed and the social environment. The cultural heritage of tattooing: a brief history -- Epidemiology of tattoos in industrialized countries -- The practise of tattooing. Tattoo machines, needles and utilities -- The technique and craftsmanship of tattooing in the professional tattoo parlour -- Tattoo as art, the drivers behind the fascination and the decision to become tattooed -- Personal records from my tattoo parlour: deep emotions drawn as life-long pictures on the skin's canvas -- Tattooist-customer relationships in a diversified environment of professional tattooists and 'scratchers' -- Tattoos and adverse events. Tattoo complaints and complications: diagnosis and clinical spectrum -- Complications of cosmetic tattoos -- Chronic tattoo reactions cause reduced quality of life equaling cumbersome skin diseases -- Contraindications for tattooing -- Laser tattoo removal, precautions, and unwanted effects -- Nano-scale observations of tattoo pigments in skin by atomic force microscopy -- Manufacturing, materials and properties of marketed tattoo ink stock products. Manufacturing of tattoo ink products today and in future -- The realistic variables underlying true safety in tattoo pigment manufacturing -- Making innovative tattoo ink products with improved safety: possible and impossible ingredients in practical usage -- Tailored surface engineering of pigments by layer-by-layer coating -- Ingredients, chemical analysis and safety of marketed tattoo ink stock products. Chemical purity and toxicology of pigments used in tattoo inks -- Survey on european studies of the chemical characterisation of tattoo ink products and the measurement of potentially harmful ingredients -- Tattoo inks: legislation, pigments, metals and chemical analysis -- The challenges and limitations of chemical analysis of particulate pigments of very low solubility -- Photostability and breakdown products of pigments currently used in tattoo inks -- Carbon black nanoparticles and other problematic constituents of black ink and their potential to harm tattooed humans -- Absorption, distribution, metabolism and excretion of tattoo colorants and ingredients in mouse and man: the known and the unknown -- Towards the limiting of health risks associated with tattooing: whitelists for tattoo pigments and preservatives -- Survey of studies on microbial contamination of marketed tattoo inks -- Regulation of and intervention in the tattoo business. The European landscape of national regulations of tattoo inks and businesses -- Implementation of European Council Resolution ResAP(2008)1 in Italy. National and regional regulation of tattoo practices: diversity and challenges -- EU actions to ensure the safety of tattoos and the protection of consumers -- Surveillance of tattoo-related adverse events by the EU RAPEX System and by national monitoring -- The Amsterdam model for control of tattoo parlours and businesses -- Hygiene standards for tattooists -- Hygiene standards in the tattoo parlour and practices for prevention of infection -- Seamless prevention of adverse events from tattooing: integrated strategy emphasising the customer-tattooist interaction -- Regulation of tattoo ink production and the tattoo business.
  • v. 1-2, 2013. Springer
    v.2 Springer
    Abdeslem El Idrissi, William J. L'Amoreaux, editors.
    Volume 1. The Nervous system, immune system, diabetes and the cardiovascular system -- Volume 2. Nutrition and metabolism, protective role, and role in reproduction, development, and differientiation.
    Also available: Print – v. 1-2, 2013
  • 2015 Springer
    Janusz Marcinkiewicz, Stephen W. Schaffer, editors.
    Taurine 9 contains original articles and critical reviews based on the oral and poster presentations of XIX International Taurine Meeting held in Kraków, Poland in May 2014. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.
    Also available: Print – 2015
  • 2006 Springer
    edited by Simo S. Oja and Pirjo Saransaari.
    Also available: Print – 2006
  • 2009 Springer
    Junichi Azuma, Stephen W. Schaffer, Takashi Ito, editors.
    Also available: Print – 2009
  • 2012 ScienceDirect
    Jules J. Berman.
    Pt. I. Principles of taxonomy. The magnitude and diversity of infectious diseases -- What is a classification? -- The tree of life -- pt. II. Bacteria. Overview of Class Bacteria -- The Alpha Proteobacteria -- Beta Proteobacteria -- Gamma Proteobacteria -- Epsilon Proteobacteria -- Spirochaetes -- Bacteroidetes and Fusobacteria -- Mollicutes -- Class Bacilli plus Class Clostridia -- Chlamydiae -- Actinobacteria -- pt. III. Eukaryotes. Overview of Class Eukaryota -- Metamonada -- Euglenozoa -- Percolozoa -- Apicomplexa -- Ciliophora (ciliates) -- Heterokontophyta -- Amoebozoa -- Choanozoa -- Archaeplastida -- pt. IV. Animals. Overview of Class Animalia -- Platyhelminthes (flatworms) -- Nematoda (roundworms) -- Acanthocephala -- Chelicerata -- Hexapoda -- Crustacea -- Craniata -- pt. V. Fungi. Overview of Class Fungi -- Zygomycota -- Basidiomycota -- Ascomycota -- Microsporidia -- pt. VI. Nonliving infectious agents : viruses and prions. Overview of viruses -- Group I viruses : double-stranded DNA -- Group II viruses : single-stranded (+)sense DNA -- Group III viruses : double-stranded RNA -- Group IV viruses : single-stranded (+)sense RNA -- Group V viruses : single stranded (-)sense RNA -- Group VI viruses : single-stranded RNA reverse transcriptase viruses with a DNA intermediate in life-cycle -- Group VII viruses : double stranded DNA reverse transcriptase viruses -- Prions -- Appendices : I. Additional notes on taxonomy -- II. Number of occurrences in some common infectious diseases -- III. Organisms causing infectious disease in humans.
  • 2011 ScienceDirect
    edited by Fred Rainey and Aharon Oren.
    Taxonomy of Prokaryotes presents experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the microbiologist interested in this specialty, this volume may be of interest to researchers working in microbiology, immunology, virology, mycology and parasitology.
  • 2007
    Ralph S. Lachman.
    Status: Not Checked OutLane Catalog Record
  • 2005 Springer
    Robert B. Taylor, editor ; associate editors, Alan K. David ... [et al.].
  • 2005 Springer
    Robert B. Taylor, editor ; associate editors Alan K. David ... [et al.].
  • 2014
    editors, Paul M. Paulman, Audrey A. Paulman, Jeffrey D. Harrison, Laeth Nasir, Kimberly Jarzynka.
    Status: Not Checked OutLane Catalog Record
    "Taylor's Differential Diagnosis manual is a quick-reference pocket book, written for primary care professionals who face diagnostic problems in brief office visits. It offers evidence-based guidelines on which key questions to ask and what data to obtain in order to provide sound diagnoses of common adult problems. More than 140 chapters in eighteen sections cover symptoms and signs in mental health problems, vision, ear nose and throat, cardiovascular, respiratory, urologic, female reproductive, musculoskeletal, dermatology and more. New for this edition are new chapters on abnormal mammogram, anticoagulation, bipolar disorder, corneal abrasion, dyspareunia and loss of vision as well as the latest clinical evidence and changes in clinical practice since the prior edition"--Provided by publisher.
  • 2015
    editors, Paul M. Paulman, Audrey A. Paulman, Kimberly J. Jarzynka, Nathan P. Falk.
    Status: Not Checked OutLane Catalog Record
  • 2008
    editors, Paul M. Paulman, Audrey A. Paulman, Jeffrey D. Harrison ; with 201 contributors.
    Status: Not Checked OutLane Catalog Record
  • 2007 Ovid
    editors, Paul M. Paulman, Audrey A. Paulman, Jeffrey D. Harrison.
    Principles of the 10-minute diagnosis / Robert B. Taylor -- Undifferentiated problems / Richard H. Hurd -- Mental health problems / Jim Medder -- Problems related to the nervous system / Michael A. Myers -- Eye problems / Shou Ling Leong -- Ear, nose, and throat problems / Frank S. Celestino -- Cardiovascular problems / Joann E. Schaefer -- Respiratory problems / Joseph E. Scherger -- Gastrointestinal problems / Michael R. Spieker-- Renal and urologic problems / R. Whitney Curry Jr. -- Problems related to the female reproductive system / Kathryn M. Andolsek -- Musculoskeletal problems / Laeth Nasir-- Dermatologic problems / Michael L. O'Dell -- Endocrine and metabolic problems / Richard D. Blondell -- Vascular and lymphatic system problems / Gregory J. Babbe -- Laboratory abnormalities : hematology and urine determinations / Carol A. LaCroix -- Laboratory abnormalities : blood chemistry and immunology / Judith A. Fisher -- Diagnostic imaging abnormalities / Enrique S. Fernandez.
    Also available: Print – 2007
  • 2006 Springer
    Robert B. Taylor, editor ; associate editors, Alan K. David ... [et al.].
    Disorders of the back and neck -- Disorders of the upper extremity -- Disorders of the lower extremity -- Osteoarthritis -- Rheumatoid arthritis and related disorders -- Selected disordeers of the musculoskeletal system -- Musculoskeletal problems of children -- Osteoporosis -- Gout -- Athletic injuries -- Care of acute lacerations -- Selected injuries.
  • 2015 Springer Protocols
    edited by Rémy Bosselut, Melanie S. Vacchio.
    200 million thymocytes and I: A beginner's survival guide to t cell development -- Development of [gamma][delta] T cells, the special-force soldiers of the immune system -- Genetic tools to study T cell development -- Assessment of T cell development by flow cytometry -- Flow cytometry analysis of thymic epithelial cells and their subpopulations -- Identifying the spatial relationships of thymic stromal and thymocyte subsets by immunofluorescence analysis -- Purification of thymocyte and T cell subsets -- Retroviral transduction of T cells and T cell precursors -- Bone marrow and fetal liver radiation chimeras -- In vitro analyses of T cell effector differentiation -- Studying T cell development in thymic slices -- FTOC-based analysis of negative selection -- Reconstituted thymus organ culture -- Induction of T cell development in vitro by delta-like (Dll)-expressing stromal cells -- In vitro analysis of thymocyte signaling -- Molecular analysis of mouse T cell receptor [alpha] and [beta] gene rearrangements -- Intrathymic injection -- Analysis of cell proliferation and homeostasis using EdU labeling -- Characterization and isolation of human T cell progenitors -- Approaches to study human T cell development -- Humanized mice to study human T cell development -- Using the zebrafish model to study T cell development.
  • 2013 Springer
    Francine Foss, editor.
    The mature T and NK cell lymphomas are rare, comprising approximately 10% of all malignant lymphomas. The incidence of T-cell lymphoma is variable around the world, with a higher incidence compared to B-cell lymphomas in the Asian basin. While the overall incidence of B-cell lymphomas has begun to decline in the United States, the incidence of T-cell lymphomas continues to rise. Over the last decade, a number of novel agents have been developed which target T-cell lymphomas and studies have identified novel genes and pathways associated with lymphomagenesis in T-cells. This comprehensive volume examines the clinical and biological aspects of the T-cell lymphoproliferative disorders in adults and children. The book includes an overview of both the cutaneous and the systemic T-cell malignancies and addresses the classification of T-cell lymphomas, the clinical features of each subtype, and the relevant molecular and genetic studies. Clinical outcomes and treatment strategies are discussed with an emphasis on the development of novel biological and targeted therapies. An outstanding resource for hematologists and oncologists, this book gathers insights from experts in the field and provides the most up-to-date information on all of the T-cell lymphoma subgroups and current and emerging therapies.
  • 2008 Ovid
    [edited by] John A. Rock, Howard W. Jones III.
    Section I: General topics affecting gynecologic surgery practice -- Operative gynecology before the era of laparoscopy: a brief history / Gert H. Brieger -- The ethics of pelvic surgery / Ruth M. Farrell, Eli A. Rybak, and Edward Wallach -- Psychological aspects of pelvic surgery / Betty Ruth Speir -- Professional liability and risk management for the gynecologic surgeon / Charles J. Ward -- The changing environment in which we practice gynecologic surgery / Eric J. Bieber and Edie L. Derian -- Training the gynecologic surgeon / Robert M. Rogers, Jr. -- Section II: Principles of anatomy and perioperative considerations -- Surgical anatomy of the female pelvis / John O. L. DeLancey -- Preoperative care / Sanford M. Markham and John A. Rock -- Postanesthesia and postoperative care / Alexander Duncan, Ira R. Horowitz, and Kenneth Kalassian -- Water, electrolyte, and acid-base metabolism / Jack B. Basil -- Postoperative infections: prevention and management / W. David Hager and John W. Larsen -- Shock in the gynecologic patient / Harriet O. Smith and Heather M. Greene -- Wound healing, suture material, and surgical instrumentation / Gary H. Lipscomb -- Section III: Principles of gynecologic surgical techniques and management of endoscopy -- Incisions for gynecologic surgery / James J. Burke II and Donald G. Gallup -- Principles of electrosurgery as applied to gynecology / Richard M. Soderstrom and Andrew I. Brill -- Application of laser gynecology / John L. Marlow -- Diagnostic and operative laparoscopy / Howard T. Sharp, Sean L. Francis, and Ana Alvarez Murphy -- Operative hysteroscopy / Michael S. Baggish -- Control of pelvic hemorrhage / Howard W. Jones III and William A. Rock, Jr. -- Section IV: Surgery for fertility -- The impact of assisted reproductive technology on gynecological surgery / Howard W. Jones, Jr. -- Reconstructive tubal surgery / Victor Gomel and Elizabeth Taylor -- Endometriosis / John S. Hesla and John A. Rock -- Section V: Surgery for benign gynecologic conditions -- Surgical conditions of the vulva / Ira R. Horowitz, Joseph Buscema, and Bhagirath Majmudar -- Surgical conditions of the vagina and urethra / Celia E. Dominguez, John A. Rock, and Ira R. Horowitz -- Surgery for anomalies of the müllerian ducts / John A. Rock and Lesley L. Breech -- Normal and abnormal uterine bleeding / William J. Butler and David E. Carnovale -- Tubal sterilization / Herbert B. Peterson, Amy E. Pollack, and Jeffrey S. Warshaw -- Surgery for benign disease of the ovary / Joseph S. Sanfilippo and John A. Rock -- Persistent or chronic pelvic pain / John F. Steege -- Pelvic inflammatory disease / Mark G. Martens -- Leiomyomata uteri and myomectomy / Lesley L. Breech and John A. Rock -- Abdominal hysterectomy / Howard W. Jones III -- Vaginal hysterectomy / S. Robert Kovac -- Laparoscopic hysterectomy / Fred M. Howard -- Section VI: Surgery for obstetrics -- Management of abortion / Melissa J. Kottke and Mimi Zieman -- Ectopic pregnancy / Mark A. Damario and John A. Rock -- Obstetric problems / Cornelia R. Graves -- Ovarian tumors complicating pregnancy / Cornelia R. Graves and Lynn Parker -- Section VII: Surgery for corrections of defects in pelvic support and pelvic fistulas -- Pelvic organ prolapse----basic principles / Carl W. Zimmerman -- Site-specific repair of cystourethrocele / Carl W. Zimmerman -- Paravaginal defect repair / Bobby Shull -- Posterior compartment defects / Thomas M. Julian -- Vaginal vault prolapse / Steven D. Kleeman and Mickey M. Karram -- The nonsurgical management of pelvic organ prolapse: the use of vaginal pessaries / Rony A. Adam -- Stress urinary incontinence / Alfred E. Bent -- Operative injuries to the ureter / Paul Underwood, Jr. -- Vesicovaginal fistula and urethrovaginal fistula / G. Rodney Meeks and Ted M. Roth -- Anal incontinence and rectovaginal fistulas / Michael P. Aronson and Raymond A. Lee -- Section VIII: Related surgery -- Breast diseases: benign and malignant / Victoria L. Green -- The vermiform appendix in relation to gynecology / Barry K. Jarnagin -- Intestinal tract in gynecologic surgery / Kelly L. Molpus -- Nongynecologic condition encountered by the gynecologic surgeon / James R. Dolan and Michael D. Moen -- Section IX: Gynecologic oncology -- Malignancies of the vulva / Mitchel S. Hoffman -- Cervical cancer precursors and their management / Howard W. Jones III -- Cancer of the cervix / Dennis S. Chi ... [et al.] -- Endometrial cancer / Marta Ann Crispens -- Ovarian cancer: etiology, screening, and surgery / John R. Van Nagell, Jr., and David M. Gershenson -- Pelvic exenteration / Thomas W. Burke -- Surgical reconstruction of the pelvis in gynecologic cancer patients / Luis E. Mendez and Manuel Penalver.
    Also available: Print – 2008
  • 2009 CRCnetBASE
    edited by Chi-Tang Ho, Jen-Kun Lin, Fereidoon Shahidi.
    Green tea and black tea: manufacturing and consumption / Xiaochun Wan, Daxiang Li, and Zhengzhu Zhang -- Pu-erh tea: its manufacturing and health benefits / Huai-Yuan Chen, Shoei-Yn Lin-Shiau, and Jen-Kun Lin -- White tea: its manufacture, chemistry, and health effects / He-Yuan Jiang -- Biological functions and manufacturing of GABA tea / Andi Shau-mei Ou, Yung-sheng Tsai, and Hsueh-fang Wang -- Production of theaflavins, theasinensins, and related polyphenols during tea fermentation / Takashi Tanaka, Yosuke Matsuo, and Isao Kouno -- Analytical methods for bioactive compounds in teas / Chi-Chun Wong .. [et al.] -- Bioavailability and metabolism of tea catechins in human subjects / Ting Sun, Chi-Tang Ho, and Fereidoon Shahidi -- Antioxidant properties and mechanisms of tea polyphenols / Xiaochun Wan, Daxiang Li, and Zhengzhu Zhang -- Mechanisms of cancer chemoprevention by tea and tea polyphenols / Jen-Kun Lin -- Effect of tea and tea constituents on inflammation / Divya Ramji ... [et al.] -- Inhibition of breast cancer cell proliferation by theaflavins and epigallocatechin 3-gallate through suppressing proteasomal activities / Jen-Kun Lin, Yu-Wen Chen, and Shoei-Yn Lin-Shiau -- Suppression of prostate carcinogenesis by tea polyphenols through inhibiting microsomal aromatase and 5-a-reductase / Jen-Kun Lin -- Green tea-induced thermogenesis controlling body weight / John Shi, Sophia Jun Xue, and Yukio Kakuda -- Fermented tea is more effective than unfermented tea in suppressing lipogenesis and obesity / Jen-Kun Lin and Shoei-Yn Lin-Shiau -- Trapping of methylglyoxal by tea polyphenols / Di Tan ... [et al.] -- Chemistry and biological properties of theanine / Xiaochun Wan, Zhengzhu Zhang, and Daxiang Li -- Flavor stability of tea drinks / Hideki Masuda.
  • 2010 ProQuest Safari
    by Lonzell Watson.
    Exploring the iPad -- Understanding what you can do with your iPad -- Configuring the iPad -- Getting the most from the internet -- Maximizing email on the iPad -- Syncing the iPad -- Getting the most from iTunes and photos -- Getting the most from YouTube and iBooks -- Managing contacts and appointments -- Simplifying your life with the iPad -- Enhance your iPad with the app store -- Maintaining and troubleshooting the iPad.
  • 2015 Springer
    Lap Ki Chan, Wojciech Pawlina, editors.
    Teaching Anatomy: A Practical Guide is the first book designed to provide highly practical advice to both novice and experienced gross anatomy teachers. The volume provides a theoretical foundation of adult learning and basic anatomy education and includes chapters focusing on specific issues that teachers commonly encounter in the diverse and challenging scenarios in which they teach. The book is designed to allow teachers to adopt a student-centered approach and to be able to give their students an effective and efficient overall learning experience. Teachers of gross anatomy and other basic sciences in undergraduate healthcare programs will find in this unique volume invaluable information presented in a problem-oriented, succinct, and user-friendly format. Developed by renowned, expert authors, the chapters are written concisely and in simple language, and a wealth of text boxes are provided to bring out key points, to stimulate reflection on the reader?s own situation, and to provide additional practical tips. Educational theories are selectively included to explain the theoretical foundation underlying practical suggestions, so that teachers can appropriately modify the strategies described in the book to fit their own educational environments. Comprehensive and a significant contribution to the literature, Teaching Anatomy: A Practical Guide is an indispensable resource for all instructors in gross anatomy.
  • 2015 Springer
    Shabih Zaidi, Mona Nasir.
    This book considers the evolution of medical education over the centuries, presents various theories and principles of learning, and discusses different forms of medical curriculum and the strategies employed to develop them, citing examples from medical schools in developed and developing nations. Instructional methodologies and tools for assessment and evaluation are discussed at length and additional elements of modern medical teaching, such as writing skills, communication skills, evidence based medicine, medical ethics, skill labs, and webinars, are fully considered. In discussing these topics, the authors draw upon the personal experience that they have gained in learning, teaching and disseminating knowledge in many parts of the world over the past four decades. .
  • Munk, Peter L.
    Status: Not Checked OutLane Catalog Record
  • 2009 Thieme Book
    editors, Mukesh G. Harisinghani, Peter R. Mueller ; assistant editor, Alejandro M. Heffess.
    An case-based reference covering the full spectrum of common and uncommon problems of the gastrointestinal and genitourinary tract encountered in everyday practice. The book organizes cases into sections based on the anatomic location of the problem. Each chapter provides succinct descriptions of clinical presentation, radiologic findings, diagnosis, and differential diagnosis for the case. The chapter then discusses the background for each diagnosis, clinical findings, common complications, etiology, imaging findings, treatment, and prognosis.
  • 2006 Thieme Book
    Mark S. Parker, Melissa L. Rosado de Christenson, Gerald F. Abbott.
    This book is a comprehensive, hands-on guide to evaluating chest images. It is ideal for reading cover-to-cover, or as a reference of radiological presentations for common thoracic disorders.The reader will learn to interpret chest images and recognize the imaging findings, generate an appropriate differential diagnosis, and understand the underlying disease process. The atlas begins with a review of normal thoracic radiography, CT, and MR anatomy, and goes on to present cases on a wide range of congenital, traumatic, and acquired thoracic conditions. Each case is supported by a discussion of etiology, pathology, imaging findings, treatment, and prognosis in a concise, bullet format to give you a complete clinical overview of each disorder. Images demonstrate normal and pathologic findings, and complementary scans demonstrate additional imaging manifestations of disease entities.
  • 2006 Thieme Book
    [edited by] Saadoon Kadir.
    Kadir (radiology, St. Louis U.) presents a guide to using interventional radiology in the treatment of non-vascular diseases of the neck, thorax, abdomen, gastrointestinal system, liver, billary system, pancreas, reproduction organs, urinary system, and adrenal glands as well as abscess drainage and biopsies. In 55 chapters, the international group of practitioners describes the clinical presentation, diagnosis, and radiological studies in addition to treatment, with illustrations in each chapter. It is the second volume to Teaching Atlas of Interventional Radiology: Diagnostic and Therapeutic Angiography.
  • 2012 Thieme Book
    László Tabár, Peter B. Dean ; with the contribution of Tibor Tot.
    "The thoroughly revised and expanded 4th edition of the bestselling "Teaching Atlas of Mammography" contains a significant number of new cases. Based on 40 years of experience, the superbly illustrated cases often show long-term follow-up of patients over a period of up to 25 years. Rather than starting with the diagnosis and demonstrating typical findings, the approach of this atlas is to teach the reader and allow him to practice through 154 paradigm cases: how to systematically review mammograms for even the most subtle hints of malignancy, and how to carefully analyze and evaluate the mammographic signs to reach the correct diagnosis. Still unique to this book is the correlation of imaging findings with the corresponding large thin-section and subgross, large thick-section (3D) histology to facilitate an understanding of the pathological processes leading to the mammographic appearances. This approach is the basis for a profound understanding of breast imaging because it is a direct and effective method of teaching differential diagnosis of benign and malignant breast diseases"--Provided by publisher.
  • 2008 Thieme Book
    [edited by] Peter L. Munk, Anthony G. Ryan.
    I. Internal Joint Derangement; II. Tumors; III. Infection; IV. Avascular bone; V. Trauma; VI. Arthritis.
  • 2006 Thieme Book
    [edited by] Paul S. Babyn.
    "Complete with the insights of leading pediatric radiologists, Teaching Atlas of Pediatric Imaging provides 125 cases that address the challenging real-life clinical problems that you are likely to encounter. Each chapter presents a different case with a complete patient work-up that includes clinical presentation, diagnosis, differential diagnoses, radiological and clinical findings, treatment summary, and suggested readings. With a view to providing the opportunity for self-assessment, the authors omit the diagnosis from the first pages of each case to enable self-testing and review."--Publisher's website.
  • 2009 Thieme Book
    Robert A. Older, Matthew J. Bassignani.
    This book presents a case-based approach to selecting the multimodality imaging strategies for the most frequently encountered urologic disorders. The book provides comprehensive coverage of the latest imaging techniques with an emphasis on newer modalities such as CT intravenous pyelograms (CT-IVP) and MRI for the genitourinary system. Each case opens with a concise description of the clinical presentation, radiologic findings, diagnosis, and differential diagnosis. It then concludes with a detailed discussion of the background, clinical findings, pathology, imaging findings, treatment, and prognosis for that case, and pertinent references. Features: Nearly 400 high-quality illustrations, including 47 in full color, demonstrate anatomy and pathology Consistent format of each chapter enhances ease of use Bulleted lists of differential diagnoses, this book provides a quick reference for common imaging findings and the most appropriate imaging strategies for specific diseases.
  • 2008 Thieme Book
    Brian Funaki, Jonathan Lorenz, Thuong Van Ha.
    Provides 75 cases that cover the full range of vascular and nonvascular interventional procedures frequently performed in clinical practice. Brief sections summarizing the clinical presentation, radiologic studies, diagnosis, and treatment guide the reader through each stage of management. For each case the authors provide the essential background on the etiology of the problem and offer bulleted lists that describe the noninvasive imaging workup, therapeutic options available, and possible complications.
  • 2012 ClinicalKey
    Girish M. Fatterpekar, Thomas P. Naidich, Peter M. Som.
    "Practical and clinically focused, Brain and Spine Imaging - a title in the Teaching Files Series - provides you with over 300 interesting and well-presented cases to help you better diagnose any disease of the brain and spine. Expert in the field, Dr. Girish Fatterpekar, MD uses a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for board exams. And, with Expert Consult functionality, you'll have convenient access to the full text online, all of the book's illustrations, additional cases and images, and links to PubMed at expertconsult.com."--Publisher's website.
  • 2010 ClinicalKey
    C. Isabela S. Silva, Nestor L. Müller.
    "Practical and clinically focused, this Chest title in the new Teaching Files Series provides you with 200 interesting and well-presented cases and nearly 600 high-quality images to help you better diagnose any disease of the chest. Experts in the field, Drs. Muller and Silva, use a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for exams. And, with Expert Consult functionality, you'll have convenient access to the full text online, all of the book's illustrations, additional cases and images, and links to Medline at expertconsult.com."--BOOK JACKET.
  • 2010 ClinicalKey
    Frank H. Miller, Stephen E. Rubesin.
  • Miller, Frank H.; Rubesin, Stephen E.
    Status: Not Checked OutLane Catalog Record
  • 2010 ClinicalKey
    Hugue A. Ouellette.
  • 2010 ClinicalKey
    Sarah Sarvis Milla, Sarah D. Bixby.
    "Drs. Sarah Milla and Sarah Bixby's The Teaching Files: Pediatrics provides you with interesting and well-presented clinical findings and images so you can better diagnose any pediatric disease. An easy-to-use, templated organization makes referencing difficult diagnoses easier than ever before. Discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. Plus, with Expert Consult functionality, you can access the full text and illustrations online from any Internet-accessible computer."--Publisher's website.
  • 2011
    edited by Thomas P. Mackey and Trudi E. Jacobson.
    Status: Not Checked OutLane Catalog Record
    Shakespeare is not a one-shot deal : an open wiki model for the humanities / John Venecek and Katheryn Giglio -- Reusable learning objects : developing online information literacy instruction through collaborative design / Matthew Sylvain, Kari Mofford, Elizabeth Lehr, and Jeannette E. Riley -- Framing multiliteracies : a blended and holistic approach to digital technology education / Andrew Whitworth, Ian Fishwick, and Steve McIndoe -- Finding your fate : the evolution of a librarian faculty collaboration to bring history online / Kristina DuRocher and Lisa Nichols -- Supported open learning : developing an integrated information literacy strategy online / Clarissa Gosling and Ingrid Nix -- Information-literate avatars : resource-based learning in Second Life / Jenna Kammer and Tracey Thompson -- Information literacy by design recalibrating graduate professional asynchronous online programs / David Lavoie, Andrew Rosman, and Shikha Sharma -- Working outside the org chart a faculty librarian partnership to design an online graduate course / Susan M. Frey and Rebecca L Fiedler.
  • 2010 Springer
    Donald McCown, Diane Reibel, Marc S. Micozzi.
    Part I: Clinical and Cultural Context -- Chapter 1. Getting grounded (in our own instability) -- Chapter 2. A history exercise to locate "mindfulness" now -- Chapter 3. Building a "working" definition of mindfulness -- Part II: Authenticity, Authority, and Friendship -- Chapter 4. The Person of the Teacher -- Chapter 5. The skills of the teacher -- Part III: Towards an "Empty" Curriculum -- Chapter 6. Organizing the intentions of teaching -- Chapter 7. Fulfilling the intentions of teaching -- Chapter 8. Practices and resources.
  • 2015 Springer
    Jochanan Benbassat.
    1. Introduction -- 2. Paradigmatic shifts in the theory, practice and teaching of medicine in recent decades -- 3. Teaching behavioral and social sciences to medical students -- 4. Difficulties in learning and teaching patient interviewing -- 5. Overcoming difficulties in teaching patient interviewing -- 6. Doctor-patient relations -- 7. Barriers to doctor-patient communication -- 8. Diagnostic utility of the physical examination and ancillary tests -- 9. Physical-examination skills: learning difficulties -- 10. Learning and teaching physical-examination skills by clinical context -- 11. Recording the clinical data base -- 12. Recording personal and social data and examination of asymptomatic persons -- 13. Recording the patient's history -- 14. Intuitive vs analytic clinical reasoning -- 15. Should clinical training rely on role modeling?.
  • v. 1, 1968
    Beckett, Peter G. S.; Bleakley, Thomas H.; Domino, Edward F.
    Status: Not Checked OutLane Catalog Record
    v. 1. Schizophrenia, paranoid conditions [and] depressions / by P.G.S. Beckett and T.H. Bleakley -- v. 2. Psychoneurosis, organic brain disease, psychopharmacology / by P.G.S. Beckett, E.F. Domino, and T.H. Bleakley.
  • 2006
    Greg R. Notess.
    Status: Not Checked OutLane Catalog Record
    1. Web searching and the teaching paradox -- Online searching background -- Internet information growth -- Origins of the Web -- Instructional background -- The teaching connection -- Teaching simplicity -- The state of Web searching today -- Changing patterns -- 2. Understanding our audience -- General audience characteristics -- Novices -- Know-it-alls -- Experienced users -- Pairing strategies for hands-on workshops -- Audience assessment -- Navigation versus search confusion -- Remembering what we did not know -- Box confusion -- Address confusion -- Button confusion -- Browser differences and problems -- Operating system and hardware issues -- Adaptability and change -- 3. Choosing an instructional session type -- Hands-on sessions -- Advantages -- Disadvantages -- Facilities -- Planning -- Exercises -- Lecture and demonstration sessions -- Advantages -- Disadvantages -- Facilities -- Planning -- Semi-online tutorials -- Capturing a screen shot within PowerPoint -- Course coverage and distance education -- Other settings and approaches -- 4. Online tutorials : friend or foe? -- Advantages -- Disadvantages -- Issues with online tutorials for Web searching -- Search engine inconsistencies -- Search feature changes -- Databases changes -- Online tutorial examples -- Web search guide tutorial : research, Web searching -- Finding information on the Internet : a tutorial -- Internet tutorials -- LearnAndGo, searching the Web -- Quick tutorial on searching the Internet -- Net.TUTOR : using Web search tools -- Interactive tutorials : Internet search tips and mouse exercise -- Tutorial : site clustering and filtering -- The information cycle -- Information literacy online tutorials -- Finding tutorials -- Tutorials : worth the effort? -- 5. Organization : focus, length, and goals -- Primary session focus -- Pure Web searching -- Basic Internet training -- Advanced Internet training -- Part of multiple sessions -- Course-integrated bibliographic instruction -- Session length -- Variations in length -- Ideal length -- The burnout paradox -- Goal setting -- A collection of goals -- How many main goals? -- Specific objectives -- Bringing it all together -- 6. Terminology -- Importance of terminology -- Definitions -- Search engine -- Directory -- Portal -- Metasearch engine -- Ad bidding engine -- Answer engine -- Metasite -- News search engine -- Opinion engine -- Site search engine -- Invisible Web -- Other terminology distinctions -- Final thoughts on terminology -- 7. Content : Web search features -- Search features -- Phrase searching -- Boolean searching -- Truncation -- Field searching -- Limits -- Stop words and case sensitivity -- Sorting -- The teaching choice -- 8. Content : primary concepts -- Research process -- Question analysis -- Using more than one search tool -- Search engines versus directories -- Evaluation -- Which primary concepts to teach -- Recent changes in teaching topics -- Additional concepts to consider -- Identifying ads -- Understanding Web addresses (or URLs) -- Understanding databases -- Teaching change -- 9. Additional content : image searching, news, Usenet, and more -- News -- Usenet newsgroups and opinions -- Pictures and images -- Multimedia -- Phone numbers -- Bibliographic databases -- Subject-specific sites -- Invisible Web -- The lost obvious -- 10. The search engines -- The starting point -- Ask -- Exalead -- Gigablast -- Google -- MSN search -- Windows Live -- Yahoo! -- Directories -- 11. Creating a framed workshop Web page -- Advantages and disadvantages of frames -- Frames code and explanation -- Top page with frameset -- Left frame table of contents -- Content pages -- Exercise pages frame set -- Exercise one top frame : JavaScript and a form -- Other exercise pages -- Solutions for frame breakers -- 12. Presentation tips, tricks, and shortcuts -- Keyboard shortcuts -- General Windows shortcuts -- Browser shortcut keys -- Shortcuts for filling out forms -- Other shortcuts -- Quick links and the personal toolbar -- Bookmarklets -- Zapping images, animations, and more -- Bookmarklets for Web searching -- The pop-up presence -- The shortcut advantage -- 13. Tales from the trenches : anecdotes, examples, and exercises -- Analogies, sayings, and terminology tales -- Boolean examples -- Exercises -- Unexpected answers -- Limitations of search engines -- Failures -- Facilities failures -- The team teaching danger -- Web site instruction and the Web searching paradox -- Lost interest -- Formulas for success -- Afterword -- Appendix A. The trainers : introduction to the interviewees -- Appendix B. Sample handouts and other training material -- Appendix C. URL list.
  • 2005 Wiley
    Alan L. Porter, Scott W. Cunningham.
    Part I. Understanding Tech Mining -- Chapter 1. Technological Innovation and the Need for Tech Mining , p. 2-15 -- Chapter 2. How Tech Mining Works, p. 17-32 -- Chapter 3. What Tech Mining Can Do for You, p. 33-40 -- Chapter 4. Example Results. Fuel Cells Tech Mining, p. 41-50 -- Chapter 5. What to Watch for in Tech Mining, p. 51-66 -- Part II. Doing Tech Mining -- Chapter 7. Forming the Right Query, p. 95-111 -- Chapter 8. Getting the Data, p. 113-127 -- Chapter 9. Basic Analyses, p. 129-154 -- Chapter 10. Advanced Analyses, p. 155-186 -- Chapter 11. Trend Analyses, p. 187-214 -- Chapter 12. Patent Analyses, p. 215-248 -- Chapter 13. Generating and Presenting Innovation Indicators, p. 249-288 -- Chapter 14. Managing the Tech Mining Process, p. 289-306 -- Chapter 15. Measuring Tech Mining Results, p. 307-320 -- Chapter 16. Example Process. Tech Mining on Fuel Cells, p. 321-354 -- Appendix A. Selected Publication and Patent Databases, p. 355-359 -- Appendix B. Text Mining Software, p. 361-362 -- Appendix C. What You Can Do without Tech Mining Software, p. 363-364 -- Appendix D. Statistics and Distributions for Analyzing Text Entities, p. 365-368.
  • 2007 Springer
    Ilse Zolle, editor.
  • 2015 Springer
    Eric Barret, Matthieu Durand, editors.
    Focal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists.
  • 2006 Springer
    S.H. Levitt ... [et al.], eds. ; with contributions by R.R. Allison ... [et al.] ; series editor's foreword by L.W. Brady, H.-P. Heilmann, M. Molls.
    Also available: Print – 2006
  • 2012 Springer
    Seymour H. Levitt, James A. Purdy, Carlos A. Perez, Philip Poortmans, editors.
    This well-received book, now in its fifth edition, is unique in providing a detailed description of the technological basis of radiation therapy. Another novel feature is the collaborative writing of the chapters by North American and European authors. This considerably broadens the book{u2019}s perspective and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first covers basic concepts in treatment planning, including essential physics and biological principles related to time-dose-fractionation, and explains the various technological approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. Issues relating to quality assurance, technology assessment, and cost-benefit analysis are also reviewed. The second part of the book discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All of the chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners in the various fields of oncology with the basic technological factors and approaches in radiation therapy.
  • v. 1, 1967.
    [by] Ralph R. Greenson.
    Status: Not Checked OutLane Catalog Record
  • v. 1, 1959-60.
    Weissberger, Arnold.
    Status: Not Checked OutLane Catalog Record
    v. 1. Physical methods of organic chemistry.
  • 19??.
    issued by the Scientific Department of the Sandoz Chemical Works.
  • 2014 Springer
    Asode Ananthram Shetty, Seok-Jung Kim, Norimasa Nakamura, Mats Brittberg, editors.
    "Cartilage defects are common. Cartilage repair surgery is not only fascinating but also surgically challenging. There are books dealing with basic science and some surgical aspect. This book fills a gap in surgical techniques for cartilage repair. All of the surgical chapters are logically organised, covering patient selection, patient setup/positioning, surgical approach, potential complications and troubleshooting. An attempt is made to compare with various surgical techniques. This book also covers anaesthesia, postoperative follow-up, pain management and rehabilitation. Both the editors and the authors are renowned experts in the field. This book will be invaluable for orthopaedic and sports medicine surgeons (consultants and training doctors) and is also of potential interest to physiotherapists, medical students, general practitioners, physical medicine and rehabilitation specialists, and rheumatology specialists."--Publisher's website.
  • 2012 Cambridge
    André Olivier, Warren W. Boling, Taner Tanriverdi.
    Machine generated contents note: Acknowledgement; Preface; History of epilepsy surgery -- The search of the epileptic focus: investigation of the surgical candidate -- Surgical anatomy -- Neuronavigation and preoperative brain mapping -- Stereoelectroencephalography (stereotactic intracranial recording) -- Anaesthesia and awake procedure -- Preoperative cortical mapping -- Endopial resection (intervascular endopial gyral emptying) -- Surgery of temporal lobe epilepsy: cortico-amygdalo-hippocampectomy -- Surgery of temporal lobe epilepsy: transcortical selective amygdalo-hippocampectomy -- Surgery of central area epilepsy -- Surgery of frontal lobe epilepsy -- Surgery of parietal lobe epilepsy -- Surgery of insular lobe epilepsy -- Surgery of occipital lobe epilepsy -- Hemispherectomy -- Callosotomy -- Epilepsy and brain tumours -- Surgical treatment of cortical dysplasias -- Reoperations in failed epilepsy surgery -- Alternate procedures -- Complications of epilepsy surgery -- Quality of life after epilepsy surgery.
  • v. 1-, 1999- ScienceDirect
    v. 9-, 2007- ClinicalKey
  • 2011 ClinicalKey
    [edited by] Jon K. Sekiya, Marc R. Safran, Anil S. Ranawat.
    Drs. Jon K. Sekiya, Marc Safran, Anil S. Ranawat, and Michael Leunig provide a step-by-step, balanced approach-with contributions from an array of North American and international surgeons-to pre-operative planning, surgical technique, technical pearls, management of complications, and post-operative rehabilitation. Surgical videos on DVD demonstrate techniques such as surgical hip dislocation for femoracetabular impingement and arthroscopic femoral osteoplasty so you can provide your patients with the best possible outcomes. Grasp the visual nuances of each technique through full-color surgical illustrations and intraoperative photographs. Watch expert surgeons perform cutting edge procedures-such as complex therapeutic hip arthroscopy using a femoral distractor, arhroscopic synovectomy and treatment of synovial disorders, surgical hip dislocation for femoracetabular important, and arthroscopic femoral osteoplasty-on DVD. Find information quickly and easily thanks to the consistent chapter format that includes technical pearls.
  • 2015 ClinicalKey
    Giles R. Scuderi, Alfred J. Tria, Jr., William J. Long, Michael N. Kang.
    Techniques in Revision Hip and Knee Arthroplasty is the one authoritative volume that gives you an efficient, problem-based approach to revision arthroplasty of both the hip and knee. Dr. Giles Scuderi and other leading experts from North America and Western Europe present their favored surgical procedures and post-surgical management strategies in this straightforward, heavily illustrated, video-intensive reference. It's your one-stop, go-to guide for successful revision surgery for a myriad of complications, such as implant loosening, polyethylene wear, osteolysis, or infection of the hip and knee. Get expert guidance on implant choice, management of complications (including infection and wound healing), and failure of mechanisms, as well as step-by-step surgical techniques.Quickly find the exact information you need with a straightforward "just what you need to know" approach, including surgical tips and pearls.Stay up to date with new insights regarding anatomic landmarks, recommended reconstruction options in revision surgery, including management of bone defects and instability.Access the fully searchable contents of the book and an abundance of surgical videos online at Expert Consult.
  • 2007 ClinicalKey
    [edited by] David J. Slutsky, Daniel J. Nagle.
    Wrist arthroscopy portals / David J. Slutsky -- Trapeziometacarpal and scaphotrapezial arthroscopy portals / David J. Slutsky -- The ulnocarpal joint. Arthroscopically assisted ulnar shortening / Daniel J. Nagle -- Arthroscopic treatment of radial-sided TFCC lesions / Jennifer Weintraub, A. Lee Osterman, and Jeffrey Yao -- Peripheral tears of the TFCC: arthroscopic diagnosis and management / Thomas E. Trumble and Seth D. Dodds -- Arthroscopy of the distal radioulnar joint / Ericka A. Lawler and Brian D. Adams -- Class IIA and B ulnar impaction: treatment with arthroscopic TFCC disc excision and wafer distal ulna resection / Matthew M. Tomaino -- Carpal ligament injury. Arthroscopic treatment of scapholunate ligament tears / Steven H. Goldberg ... [et al.] -- Arthroscopic RASL / Michael R. Hausman -- Arthroscopic thermal shrinkage for scapholunate ligament injuries / Ferdinando Battistella, Pau Golano, and Ettore Taverna -- Arthroscopic treatment of lunotriquetral ligament injuries / Gregory J. Hanker -- Arthroscopic plication of lunotriquetral ligament tears / Jason W. Levine, Felix H. Savoie III, and Michael J. Moskal -- Arthroscopic dorsal readiocarpal ligament repair / David J. Slutsky -- The role of arthroscopy in midcarpal instability / David M. Lichtman ... [et al.] -- Capsular shrinkage in the treatment of wrist instability / David J. Nagle -- Writst and carpal fractures. Arthroscopically assisted reduction and percutaneous fixation of scaphoid fractures using a simple external targeting system / Joseph F. Slade III and Greg Merrell -- The role of wrist arthroscopy in intra-articular distal radius fracture management / William B. Geissler -- Correction of mal-united intra-articular distal radius fractures with and inside-out osteotomy technique / Franscisco del Piñal -- Arthroscopic wrist capsulotomy / David J. Slutsky -- Arthroscopic synovectomy and abrasion chondroplasty of the wrist / Kevin D. Plancher and Césaw J. Bruno -- Arthroscopic wrist ganglionectomy / Randy R. Bindra -- Arthroscopic treatment of volar carpal ganglion cysts / Jeffrey A. Greenberg -- Arhtoscopically assisted treatment of intraosseous gaglions of the lunate / N. Ashwood and G.I. Bain -- Arthroscopic radial styloidectomy / David J. Slutsky -- Arthroscopic resection of arthosis of the proximal hamate / Brian J. Harley and Andrew K. Palmer -- Arthroscopic proximal row carpectomy / Randall W. Culp and Eric S. Wroten -- Anthroscopy of the small joints of the hand / Richard A. Berger -- Small-joint arthroscopy. Arthroscopic treatment of trapeziometacarpal diseaes / David J. Slutsky -- Arthroscopic debridement for isolated scaphotrapeziotrapezoid arthritis / N. Ashwood and G.I. Bain -- Extra-articular procedures. Agee endoscopic carpal tunnel release / David J. Slutsky -- Endoscopic carpal tunnel release: the chow dual-portal technique / Daniel J. Nagle -- Endoscopic release of the first dorsal extensor tendon compartment / Joseph F. Slade III and Greg Merrell.
  • 2015 Springer
    Rifat Latifi, Peter Rhee, Rainer W.G. Gruessner, editors ; foreword by David B. Hoyt.
    Ther New Surgeon: Patient-Centered, Disease-Focused, Technology-Driven, and Team-Oriented -- The Ever-Changing Departments of Surgery: The New Paradigm-The Roadmap to a Modern Department of Surgery -- Genomics in Surgery, Trauma, and Critical Care: How Do We Control the Future? -- Nanotechnologies in Surgery: The New Paradigm -- Telemedicine for Trauma and Intensive Care: Changing the Paradigm of Telepresence -- Augmented Reality in Surgery -- The Lean Innovation Model for Academic Medical Discovery -- Changing the Protocol: Is There Still Room for the Professor's Viewpoint? -- Ethical Implications of Advanced Technologies in Surgical Care. Dedicated Resuscitation Operating Room for Trauma -- End Points Resuscitation -- Abdominal Trauma: Not Everything that Bleeds Needs and Operation -- Neurosurgical Advances in Trauma Management -- Damage Control and Organ Injury Priority Management of Trauma Patients -- Multiorgan Dysfuction in Trauma and Surgical Intensive Care Units -- Advances in Burn Care -- Biology of Nutrition Support and Gut Access in Critically Ill Patients -- Advances in Head and Neck Surgery -- Neck Cancer: Imaging Techniques and Progress on the Operative Approach -- Advances in Thyroid and Parathyroid Care -- Neuron Based Surgery: Are We There Yet? Technical Developments in the Surgical Treatment of Brain Injury and Disease -- Brain Cancer: The New Frontiers -- Advanced Thoracoscopic Surgery to Modern Pulmonary Disease: The Japanese Approach -- The Role of Robotics in Selective Throacic Surgical Problems: Technical Considerations -- Cardiac Surgery Advances: Do We Still Remember How to Do Open Bypass? -- Artificial Hearts and Cardiac Assist Devices: The Spectrum of the New Era -- New Valves: Where Do We Stand? -- Technological Advances in Endovascular Surgery -- Carotid Disease: The Stents and the Evidence-Based Medicine-What Happened to the Old Surgery? -- Laporascopic Approaches in General Surgery: Is There Anything New? -- Robotic Applications in Advancing General Surgery -- Natural Orifice Transluminal Endoscopic Surgery (NOTES) -- Bariatric Surgery: The Less, The Better -- New Minimally Invasive Treatments for Acid Reflux -- Minimally Invasive Hepato-Pancreato-Biliary Surgery and Associated GI Interventions -- Pancreatic Advances -- Laparoscopic Liver Resection for Hepatocellular Carcinoma -- Advances in Colorectal Surgery -- Technological Advances in Heart and Lung Transplantation: Concomitant Cardiac Valve Surgery -- Abdominal Organ Transplantation: An Overview -- Small Bowel Transplantation: Is There a Hope on the Horizon? -- Islet Cell Transplantation: New Techniques for an Old Disease -- Face Transplant: The Future is Better Than Current Concepts -- Limp Transplantation -- Advances in Immunosuppressive Therapy -- Tissue Repair and Wound Healing: A Trip Back to the Future -- Surgical Advances in the Treatment of Abdominal Wall Hernias -- Use of Biologic Grafts in Surgery -- Artifical Limbs for Upper Extremity Amputation -- Advanced Technologies in Pediatric Critical Care/Surgery and Fetal Surgery.
  • 2014 Karger
    volume editors, Daniela Bruttomesso, Giorgio Grassi.
    Glycemic control -- Home blood glucose monitoring -- Continuous glucose monitoring -- Insulin delivery system -- Closed-loop insulin-delivery system -- Alternatives to insulin injection -- Devices to support treatmtne decisions -- Electronic medical record.
  • 2011 CRCnetBASE
    editors, R.M. Natal Jorge, João Manuel R.S. Tavares, Marcos Pinotti Barbosa, Alan Peter Slade.
  • 2011
    Junhee Seok.
    Translation of knowledge from basic science to medicine is essential to improving both clinical research and practice. In this translation, high-throughput genomic approaches can greatly accelerate our understanding of molecular mechanisms of diseases. A successful high-throughput genomic study of disease requires, first, comprehensive and efficient platforms to collect genomic data from clinical samples, and second, computational analysis methods that utilize databases of prior biological knowledge together with experimental data to derive clinically meaningful results. In this thesis, we discuss the development of a new microarray platform as well as computational methods for knowledge-based analysis along with their applications in clinical research. First, we and other colleagues have developed a new high-density oligonucleo-tide array of the human transcriptome for high-throughput and cost-efficient analysis of patient samples in clinical studies. This array allows comprehensive examination of gene expression and genome-wide identification of alternative splicing, and also pro-vides assays for coding SNP detection and non-coding transcripts. Compared with high-throughput mRNA sequencing technology, we show that this array is highly re-producible in estimating gene and exon expression, and sensitive in detecting expres-sion changes. In addition, the exon-exon junction feature of this array is shown to im-prove detection efficiency for mRNA alternative splicing when combined with an ap-propriate computational method. We implemented the use of this array in a multi-center clinical program and have obtained comparable levels of high quality and re-producible data. With low costs and high throughputs for sample processing, we antic-ipate that this array platform will have a wide range of applications in high-throughput clinical studies. Second, we investigated knowledge-based methods that utilize prior know-ledge from biology and medicine to improve analysis and interpretation of high-throughput genomic data. We have developed knowledge-based methods to enrich our prior knowledge, illustrate dynamic response to external stimulus, and identify distur-bances in cellular pathways by chemical exposure, as well as discover hidden biological signatures for the prediction of patient outcomes. Finally, we applied a knowledge-based approach in a large scale genomic study of trauma patients. Cooperating with clinical information, prior knowledge improved the interpretation of common and dif-ferential genomic response to injury, and provided efficient risk assessment for patient outcomes. The clinical and genomic data as well as analysis results in this trauma study were systematically organized and provided to research communities as new knowledge of traumatic injury. The microarray platform and knowledge-based methods presented in this thesis provide appropriate research tools for high-throughput translational medicine in a large clinical setting. This thesis is expected to advance understanding and treatment for dis-eases, and finally, improve public health.
  • 2012 Springer
    edited by Kendall Ho, Sandra Jarvis-Selinger, Helen Novak Lauscher, Jennifer Cordeiro, Richard Scott.
    Rapid progress in health research has led to generation of new knowledge and innovative practices in management of illness. This has resulted in a significant challenge for health professionals: if today we discovered a new therapy through research, when will this discovery be regularly prescribed or utilized to treat all patients suffering from this condition? Knowledge translation is the non-linear and often complicated process of translating knowledge into routine health practices. Technology enabled knowledge translation (TEKT) is the use of information and communication technologies (ICT) to accelerate knowledge translation. With the ubiquity of the internet, the proliferation of different approaches in communication and social networking, and the continuously improving technologies from netbooks to smartphones, there are rich opportunities for TEKT in health education, service delivery, and research.
  • 2010 Springer
    Dennis R. Cooley.
    Applied groundwork for a practical moral code. Introduction ; Definitions ; Professional moral codes ; USDA study : methodology and results ; Formalization and evaluation of the USDA study's moral codes ; Formalization of the combination moral code ; Problems for the combination moral code ; Conclusion -- A practical moral code. Introduction ; Utilitarianism ; What is a reasonable person? ; RPU's benefits ; Respecting persons ; Working toward a plausible distributive/social justice principle ; The moral paradigm test ; Conclusion -- Are transgenic organisms, biotechnology, and technology unnatural? Introduction ; The unnatural is unethical argument ; The weak definitions ; A "playing God" argument ; More complex meanings of the unnatural ; Arguments from evolution ; Conclusion -- A natural theory of value. Introduction ; Naturalness as sacredness ; Beginning an axiology ; The benefit of the doubt principle ; Intrinsically valuable things and their rankings ; Is nature or the biosphere alive? ; Arguments against nature's intrinsic value ; Conclusion -- Applying PMC to a few transgenic technology issues. Introduction ; The practical moral code again ; Transgenics and RPU ; Transgenics and QCI ; Legal/moral questions ; Conclusion.
  • 2011 ClinicalKey
    Leanne Groban, John F. Butterworth IV.
    Wake Forest University -- Basic Physics of Ultrasound -- Systolic LV Structure/Function -- Diastolic Function -- Aortic Valve Anatomy -- Aortic Valve Stenosis -- Aortic Regurgitation -- Mitral Valve Anatomy -- Mitral Valve Stenosis -- Mitral Valve Regurgitation -- Pulmonic Valve -- Tricuspid Valve -- Right Ventricle -- Prosthetic Valve Types -- Eendocarditis -- Pericardial Disease -- Aoritc Atherosclerosis Aneurysm Dissection -- Adult Congenital Heart Disease -- Intracardiac Masses and Objects -- Artifacts and Pitfalls -- Equations and Calculations -- Intraoperative Aoperative ₃-Dimensional (₃D) Tee.
  • 2006 Karger
    volume editor, Ralph M. Duckworth.
    On the relationship between calculus and caries / Duckworth, R.M., Huntington, E. -- The structure, function and properties of the acquired pellicle / Hannig, M., Joiner, A. -- Model parameters and their influence on the outcome of in vitro demineralisation and remineralisation studies / Lynch, R.J.M. -- Tooth wear / Pickles, M.J. -- Nanomechanics, chemistry and structure at the enamel surface / Mann, A.B., Dickinson, M.E. -- Plaque as a reservoir for active ingredients / Duckworth, R.M., Gao, X.J.
  • 2009 Springer
    Gérard Tilles.
  • 2013
    Stacey B. Day.
    Status: Not Checked OutLane Catalog Record
  • 2013 CRCnetBASE
    (ed.) Fei Hu. The University of Alabama, Electrical and Computer Engineering, Tuscaloosa, Alabama, USA.
    Pt. 1. System : tele-healthcare monitoring networks -- pt. 2. Hardware : medical sensors and devices -- pt. 3. Software : medical signal processing -- pt. 4. Others : medical security and privacy.
  • 2016 Springer
    Raymond K. Cross, Andrew R. Watson, editors.
    This volume provides a comprehensive, state-of-the art review of inflammatory bowel disease and its management through the use of telemedicine applications. The book reviews barriers to successful outcomes in patients with IBD and offers a rationale for how self-management and telemedicine approaches can improve care in chronic illnesses such as IBD. This volume also includes a summary of the burden of telephone encounters in patients with IBD, characteristics of frequent callers to the office, outcomes associated with high telephone use, and strategies to provide education via telephone to patients with IBD. Prior literature on implementation of teleconsultation in research and clinical practice, as well as mobile applications used to track symptoms, quality of life, diet, and medication use in IBD are also explored in the book. Written by experts in the field, Telemanagement of Inflammatory Bowel Disease is a valuable resource for gastroenterologists, surgeons, and other clinicians dealing with, and interested in, this novel adjunct to routine care for inflammatory bowel disease.
  • 2014 Springer
    Fabio Capello, Andrea E. Naimoli, Giuseppe Pili, editors.
    "This book describes in detail the potential role of ICT and electronic systems, together with the application of Web 2.0 technologies, in telepediatrics and child health. Rather than simply proposing engineering solutions that may soon become outdated, it is designed to address those real needs that telemedicine and developers are asked to meet. The orientation of the book is very much toward primary care, and both low- and high-income settings as well as extreme or complex scenarios are considered. The first two sections of the book describe different fields of application, such as the community, the hospital, and children with chronic illnesses or special needs, and examine technical issues. The use of telemedicine in delivery of care in extreme rural settings and developing countries is then discussed, with attention also to major emergencies and humanitarian crises. The closing chapters consider the role of modern technologies in the education of caregivers who work with children. Child health is a crucial issue in both industrialized and developing countries. Telemedicine for Children's Health will be an excellent guide to the potential value of telemedicine devices in reducing the burden for children and parents and in offering quick and concrete solutions in low-resource scenarios"--Provided by publisher.
  • 2012 Springer
    edited by Hans Peter Soyer, Michael Binder, Anthony C. Smith, Elisabeth M.T. Wurm.
    Introduction to Teledermatology -- Historical Review -- Medical Prerequisites -- Technical Prerequisites -- Photographic Imaging Essentials -- Performance of Teledermatology including Clinical Examples -- Teledermatology in Underdeveloping Countries -- Special Methods of Teledermatology -- Teledermatology and Reflectance Confocal Microscopy Quality Assurance -- Legal Assumptions -- Economic Aspects and Cost-effectiveness -- Future Horizons -- APPENDIX: Education and Training Opportunities -- Quality Certificate Teledermatology -- Sample Protocol, Consent Form and Information Sheet -- References and Relevant Web links -- Glossary -- Subject Index.
  • 2013 Springer
    Philippe A. Liverneaux, Stacey H. Berner, Michael S. Bednar, Sijo J. Parekattil, Gustavo Mantovani Ruggiero, Jesse C. Selber, editors.
    Part 1. GENERAL -- History of Microsurgery / Yoshikazu Ikuta -- History of Telesurgery / James Wall and Jacques Marescaux -- Description of Robots / Jesse Creed Selber -- Instruments / Sijo Joseph Parekatti and Michael Moran -- Robot Installation in Telemicrosurgery / Thierry Lequint, Kiyohito Naito, Eric Nectoux, Sybille Facca and Philippe Liverneaux -- Part 2. TRAINING -- Earthworms / Gustavo Mantovani Ruggiero -- Vessels / Joo-Yup Lee and Alexander Y. Shin -- Nerves / Stacey H. Berner -- Part 3. EXPERIMENTAL RESEARCH -- Free Tissue Transfer / Stacey H. Berner -- Tele-endomicrosurgery / Sybille Facca, Kiyohito Naito, Thierry Lequint, Eric Nectoux and Philippe Liverneaux -- Brachial Plexus Repair / Gustavo Mantovani Ruggiero and Philippe Liverneaux -- Tendon Transfer / Michael S. Bednar -- Part 4. CLINICAL APPLICATIONS -- Nerve Entrapment / Jose Carlos Garcia Jr. -- Nerve Repair / Stacey H. Berner -- Brachial Plexus / Kiyohito Naito, Mickaël Ohana, Thierry Lequint, Sybille Facca and Philippe Liverneaux -- Skin Flaps / Thomas Lauwers, Tom Van Mulken and Darren Booi -- Muscle Flaps / Jesse Creed Selber and John C. Pedersen -- Head and Neck / Jesse Creed Selber -- Urology / Sijo Joseph Parekattil -- Part 5. PERSPECTIVES -- Supermicrosurgery / Takeshi Todokoro and Isao Koshima -- Network / Catherine Jane Mohr.
  • 2011 Springer
    A.J. Larner.
    "Medical information is now widely available on the Internet and through telephone helplines such as NHS Direct and the focus on patient self care is likely to increase. Clinicians in all specialties will often encounter patients who have made self-directed searches for medical information prior to the clinical encounter. 'Teleneurology by Internet and Telephone' is a study of patient information-seeking behaviour in neurology patients prior to referral from primary to secondary care. The book analyses frequency of Internet access and use, and of telephone helpline awareness and use. It also explores use of these modalities over time, use according to patient gender and age and by gender and age over time. 'Teleneurology by Internet and Telephone' is an accessible overview of the utility of these modalities of health information provision and will be of interest not only to neurologists and clinicians in other specialities but also to public health researchers, sociologists and political scientists with an interest in questions of health care provision"--Provided by publisher.
  • 2015 Springer
    Jack W. Tsao, Bart M. Demaerschalk, editors.
    Teleneurology in the United States Veteran Health Administration -- International Teleneurology -- Military Telemedicine -- Telemedicine Technology -- Telestroke -- Teleneurointensive Care Unit (TeleneurolICU) -- Teleneurology and Neurointerventional Therapy for Acute Stroke -- Teleneurosurgery -- Hospital Teleneurology -- Telemedicine and Parkinson Disease -- Telebeuropatholgy -- Tele-Epilepsy and Tele-Electroencephalography -- The Emerging Relevance of Telemedicine in Sleep Medicine -- Teledementia -- The Emerging Role of Telemedicine in the Evaluation of Sports-related Concussion -- Teleneurology in Contemporary Graduate Medical Education -- Legal Considerations in the Use of Telemedicine in Neurology -- Reimbursement in Teleneurology.
  • 2011 Springer
    Sajeesh Kumar, Helen Snooks, editors.
  • 2015 Springer
    Giovanna Gatti, Gabriella Pravettoni, Fabio Capello, editors.
    1 Introduction -- 2 Overview and Background -- PART I -- Fields of application 3 The community: Early diagnosis and prevention -- 4 The hospital: Improving hospital care for people with cancer -- 5 Home-based care for a better quality of life: Treatment, monitoring and follow-up -- PART II -- Technical Issues 6 New technologies and new frontiers -- 7 The social web -- PART III -- Complex Scenarios and Special Settings -- 8 Rural and extreme rural settings -- 9 Tele-oncology in developing countries -- PART IV -- eLearning 10 Education and distant learning -- 11 Health education to improve prevention -- 12 Conclusions.
  • 2006 Springer
    Kanagasingam Yogesan ... [et al.], editors.
  • 2015 Springer
    Georg Michelson, editor.
    Applications of Teleophthalmology: Systemic Diseases (Applications) -- Ocular Diseases. Methods used in Teleophthalmology: Novel Imaging Devices -- Information Technologies.
  • 2009 Springer
    Sajeesh Kumar, Bruce E. Dunn, (eds.).
  • 2008 Springer
    edited by Sajeesh Kumar, Elizabeth Krupinski.
  • 2013 Springer
    Sajeesh Kumar, Ellen R. Cohn, editors.
    Telerehabilitation, as a subset of telehealth, is the use of telecommunications to deliver rehabilitation services at a distance and can bridge the gaps created by personnel shortages that exist in underserved and remote areas, as well as serve persons in urban settings who cannot easily leave their homes or offices to seek care. Given the mobile nature of our society, telerehabilitation can enable continuity of care while persons travel for work, vacation and/or education. While the technical capacities to conduct telerehabilitation have surged ahead in the past 10 years, there has been slower, yet ongoing progress in the development of the policies (e.g., legislation; state licensure; reimbursement) that will be required to actualize widespread telepractice service delivery. Telerehabilitation presents a wide-angle view of telerehabilitation worldwide at a seminal time in its development. The book contains contributions from authors across multiple disciplines, as well as a consumer-based perspective. This book contributes significantly to the current understanding of telerehabilitation, as well as elucidating the immense potential for telerehabilitation-based service delivery to benefit persons with disabilities.
  • 2008 Springer
    Sajeesh Kumar, Jacques Marescaux (eds.).
  • 2009
    Jinkuk Choi.
    Status: Not Checked OutLane Catalog Record
  • 2007 Springer Protocols
    edited by Lucy G. Andrews and Trygve O. Tollefsbol.
    Methods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.
  • 2011 Springer Protocols
    edited by Zhou Songyang.
    Introduction to telomeres and telomerase / Z. Songyang -- Analysis of average telomere length in cultured human cells / D. Liu -- Telomere length analysis by quantitative fluorescent in situ hybridization (Q-FISH) / I. Ourliac-Garnier and A. Londono-Vallejo -- Telomere strand-specific length analysis by fluorescent in situ hybridization (Q-CO-FISH) / I. Ourliac-Garnier and A. Londono-Vallejo -- Telomere G-overhang length measurement method 1: The DSN method / Y. Zhao, J.W. Shay and W.E. Wright -- Telomere G-overhang length measurement method 2: G-tail telomere HPA / H. Tahara -- Telomere terminal G/C strand synthesis: Measuring telomerase action and C-RICH fill-in / Y. Zhao, J.W. Shay and W.E. Wright -- G-quadruplex structures and G-quadruplex-interactive compounds / R.I. Mathad and D. Yang -- Analysis of yeast telomerase by primer extension assays / M. Hsu and N.F. Lue -- Telomeric repeat amplification protocol: Measuring the activity of the telomerase / H. Xin -- CO-FISH, COD-FISH, ReD-FISH, SKY-FISH / E.S. Williams [and others] -- Visualization of human telomerase localization by fluorescence microscopy techniques / E. Abreu, R.M. Terns and M.P. Terns -- Cytogenetic analysis of telomere dysfunction / A.S. Multani and S. Chang -- Probing the telomere damage response / R. Rai and S. Chang -- Analysis of telomere proteins by chromatin immunoprecipitation (CHIP) / W. Ma -- Studying of telomeric protein-protein interactions by bi-molecular fluorescence complementation (BIFC) and peptide array-based assays / W. Ma, H. Kim and Z. Songyang -- Human telomere POT1-TPP1 complex and its role in telomerase activity regulation / F. Wang and M. Lei.
  • 2008 Springer
    K. Lenhard Rudolph, editor.
  • 2009 Springer
    Keiko Hiyama, editor.
  • 2006
    edited by Titia de Lange, Vicki Lundblad, Elizabeth Blackburn.
    Status: Not Checked OutLane Catalog Record
    A history of telomere biology -- The telomerase ribonucleoprotein particle -- Telomerase biochemistry and biogenesis -- Telomerase and human cancer -- Modeling cancer and aging in the telomerase-deficient mouse -- Telomerase deficiency and human disease -- Telomerase-independent maintenance of mammalian telomeres -- Telomerase-independent telomere maintenance in yeast -- Meiotic telomeres -- Telomere position effect : silencing near the end -- The structural biology of telomeres -- Budding yeast telomeres -- Mammalian telomeres -- Drosophila telomeres -- Ciliate telomeres -- Fission yeast telomeres -- Plant telomeres.
  • 2008 Springer
    James F. Hancock, editor.
  • 2005 CRCnetBASE
    Christopher J. Gordon.
  • 2010 Springer
    John I. Lane, Robert J. Witte.
    Imaging Technique -- Anatomy -- Multiplanar Atlas -- Advanced Imaging Applications -- Imaging Microscopy of the Temporal Bone: An Anatomy Tutorial.
  • 2015 Springer
    Jan Kopřiva, Jan Žižka.
    This book, featuring more than 180 high spatial resolution images obtained with state-of-the-art MDCT and MRI scanners, depicts in superb detail the anatomy of the temporal bone, recognized to be one of the most complex anatomic areas. In order to facilitate identification of individual anatomic structures, the images are presented in the same way in which they emanate from contemporary imaging modalities, namely as consecutive submillimeter sections in standardized slice orientations, with all anatomic landmarks labeled. While various previous publications have addressed the topic of temporal bone anatomy, none has presented complete isotropic submillimeter 3D volume datasets of MDCT or MRI examinations. The Temporal Bone MDCT and MRI Anatomy offers radiologists, head and neck surgeons, neurosurgeons, and anatomists a comprehensive guide to temporal bone sectional anatomy that resembles as closely as possible the way in which it is now routinely reviewed, i.e., on the screens of diagnostic workstations or picture archiving and communication systems (PACS).
  • 2008 Thieme Book
    Ellen G. Hoeffner [and others].
    This new text covers the most important concepts of temporal bone imaging. Each chapter is organized by disease entity, including congenital malformations, neoplasms, infections/inflammatory, post-operative and more. With a wealth of information provided in an easy-to-read format, this text is ideal for neuroradiologists, radiologists and other specialists.
  • 2015 Springer
    edited by Marc Lemmerling, Bert de Foer.
    This book provides a complete overview of imaging of normal and diseased temporal bone. After description of indications for imaging and the cross-sectional imaging anatomy of the area, subsequent chapters address the various diseases and conditions that affect the temporal bone and are likely to be encountered regularly in clinical practice. The classic imaging methods are described and discussed in detail, and individual chapters are included on newer techniques such as functional imaging and diffusion-weighted imaging. There is also a strong focus on postoperative imaging. Throughout, imaging findings are documented with the aid of numerous informative, high-quality illustrations. Temporal Bone Imaging, with its straightforward structure based essentially on topography, will prove of immense value in daily practice.
  • 2007 Springer
    edited by John A. Bissonette, Ilse Storch.
  • 2016 Springer
    Louis G. Mercuri, editor ; foreword by Joshua J. Jacobs.
    Part I Introduction -- Introduction -- TMJ Biomechanics -- TMJ TJR Biomaterials Considerations -- History of TMJ TJR (Mercuri) -- Part II TMJ TJR Devices -- Stock TMJ TJR Devices -- Custom TMJ TJR Devices -- Part III Advanced TMJ TJR Techniques -- TMJ TJR in combination with orthognathic procedures -- Mandibular replacement utilizing TMJ TJR devices -- Part IV Complications -- TMJ TJR surgical Complications, prevention and management -- Material Hypersensitivity -- Tribocorrosion and TMJ TJR devices -- Management of failing and failed TMJ TJR Devices -- Part V Future Considerations -- Bioengineered Tissue TMJ TJR.
  • 2013
    Antonio Nanci, PhD.
    Status: Not Checked OutLane Catalog Record
    Structure of the oral tissues -- General embryology -- Embryology of the head, face, and oral cavity -- Cytoskeleton, cell junctions, fibroblasts, and extracellular matrix -- Development of the tooth and its supporting tissues -- Bone -- Enamel : composition, formation, and structure -- Dentin-pulp complex -- Periodontium -- Physiologic tooth movement : eruption and shedding -- Salivary glands -- Oral mucosa -- Temporomandibular joint -- Facial growth and development -- Repair and regeneration of oral tissues.
  • 2005 CRCnetBASE
    Anna Tramontano.
  • 2007 Ovid
    [edited by] Hugh A. McAllister Jr., James T. Willerson.
    Sect. I: Pulmonary arteries, aorta, peripheral vessels -- Sect. II: Coronary arteries -- Sect. III: Intracardiac masses -- Sect. IV: Endocardium and valves -- Sect. V: Pericardium and myocardium -- Sect. VI: Congenital heart disease.
  • 2013 Springer
    Edward K. L. Chan, Marvin J. Fritzler, editors.
    Introduction: The GW Body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology -- The Discovery of GW Bodies -- The Discovery and Analysis of P Bodies -- Autoantibodies to Argonaute 2 (Su Antigen) -- GW/P-Bodies and Autoimmune Disease -- Function of GW182 and GW Bodies in siRNA and miRNA Pathways -- Post-transcriptional Stimulation of Gene Expression by MicroRNAs -- Gawky (GW) is the Drosophila melanogaster GW182 Homologue -- The Role of GW182 Proteins in miRNA-Mediated Gene Silencing -- Quantifying Argonaute Proteins In and Out of GW/P-Bodies: Implications in microRNA Activities -- Deadenylation and P-Bodies -- Relationship of GW/P-Bodies with Stress Granules -- Relationship of Other Cytoplasmic Ribonucleoprotein Bodies (cRNPB) to GW/P Bodies -- An SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 -- Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research.
    Also available: Print – 2013
  • 2005 Springer
    Nicola Maffulli, Per Renström, Wayne B. Leadbetter, editors.
    Part I. Basic Sciences, Etiology, Pathomechanics, and Imaging --1. Anatomy of Tendons / Moira O'Brien, p. 3-13 -- 2. Mechanical Properties of Tendons / Constantinos Maganaris and Marco Narici, p. 14-21 -- 3. Growth and Development of Tendons / Laurence Dahners, p. 22-24 -- 4. Aging and Degeneration of Tendons / Pekka Kannus, Mika Paavola and Lászlo Józsa, p. 25-31 -- 5. Epidemiology of Tendon Problems in Sport / Mika Paavola, Pekka Kannus and Markku Järvinen, p. 32-39 -- 6. Neurogenic, Mast Cell, and Gender Variables in Tendon Biology: Potential Role in Chronic Tendinopathy / David Hart, Cyril Frank, Alison Kydd, Tyler Ivie, Paul Sciore and Carol Reno, p. 40-48 -- 7. Imaging of Tendon Ailments / Tudor Hughes, p. 49-60 -- Part II. Anatomical Sites and Presentation -- 8. Injury of the Musculotendinous Junction / Jude Sullivan and Thomas Best, p. 63-69 -- 9. Insertional Tendinopathy in Sports / Per Renström and Thomas Hach, p. 70-85 -- 10. Tendon Avulsions in Children and Adolescents / Sakari Orava and Urho Kujala, p. 86-89.
    Also available: Print – 2005
  • 2012 ClinicalKey
    editor-in-chief, Jin Bo Tang ; editors, Peter C. Amadio, Jean-Claude Guimberteau, James Chang ; contributing editors, David Elliot, Judy Colditz.
    "Get the best results from the latest procedures with Tendon Surgery of the Hand , the only reference that offers comprehensive coverage of this complex and challenging area. World-renowned experts guide you through all of the newest techniques and technologies , equipping you to restore optimal function in your patients. It's your one-stop source for mastering today's best approaches to treating tendon injuries and disorders of the hand."--Publisher's website.
  • 2011 Springer
    [edited by] Philippe Valenti.
  • 2015 Springer
    Jennifer Moriatis Wolf, editor.
    Section I: Etiology -- Definition, Causes and Epidemiology -- Tennis Elbow in Athletes: More Than Just Tennis? -- Golfer's Elbow: Treatment Distinctions -- Section II: Conservative Treatment -- Evidence for No Treatment and Self-limited Treatment -- Medical Management: The Role of NSAIDS and Topical -- Therapy -- Splints -- Steroid Injections -- Blood and PRP Injections -- Other Treatments: Prolotherapy, Acupuncture, ESWL -- Section III: Surgery -- Open Surgical Treatment -- Arthroscopic Treatment -- Denervation -- Percutaneous Release -- Outcomes of Treatment and Return to Play: The Evidence -- Complications of Surgical Treatment and Salvage Procedures for Failed Surgery.
  • 2009 Springer
    a cura di Angelo Sghirlanzoni.
  • 2013 Springer Protocols
    edited by Paul C. Barrow.
    ICH S5(R2) guideline for the testing of medicinal agents / L. David Wise -- Nonclinical reproductive toxicity testing requirements for drugs, pesticides, and industrial chemicals in India and China / K.S. Rao and Jing Dong -- Developmental toxicity testing of biologics / Keith P. Hazelden -- OECD guidelines for the testing of chemicals and pesticides / Jochen Buschmann -- Teratology testing under REACH / Steve Barton -- Teratology testing of food additives / Paul C. Barrow and Francois Spezia -- Developmental toxicity testing of vaccines / Paul C. Barrow and Linda Allais -- Teratology testing of cosmetics / Francois Spézia and Paul C. Barrow -- Teratology studies in the rat / Mariline Leroy and Linda Allais -- Teratology studies in the mouse / Edward Marsden and Mariline Leroy -- Combined fertility and embryotoxicity study / Lucie Reynaud and Edward Marsden -- Teratology studies in the rabbit / Linda Allais and Lucie Reynaud -- Teratology studies in the minipig / Peter A. McAnulty -- Embryo fetal development studies in nonhuman primates / Antje Fuchs, Eberhard Buse, and Gerhard F. Weinbauer -- Enhanced pre- and postnatal development study for monoclonal antibodies / Gerhard F. Weinbauer, Joerg Luft, and Antje Fuchs -- Skeletal examination by alizarin staining / Lucie Reynaud and Audrey Jocteur-Monrozier -- Skeletal examination by double staining for ossified bone and cartilaginous tissue / Steffen Schneider -- Small animal imaging and examination by micro-CT / Sergio X. Vasquez, Neha Shah, and Alan M. Hoberman -- Fetal soft tissue examination by serial sectioning / Karon Critchell -- Fetal soft tissue examinations by microdissection / Mariline Leroy and Audrey Jocteur-Monrozier -- Soft tissue examination of the fetal rat and rabbit head by magnetic resonance imaging / Julian M. French and Neil Woodhouse -- Historical control data in reproductive and developmental toxicity studies / Eve Mylchreest and Stephen B. Harris -- Reporting of teratology studies / Paul C. Barrow and Lucie Reynaud -- Maternal toxicity / Bengt R. Danielsson -- Innovations in testing strategies in reproductive toxicology / Aldert H. Piersma -- Predictive models and computational toxicology / Thomas Knudsen, Matthew Martin, Kelly Chandler, Nicole Kleinstreuer, Richard Judson, and Nisha Sipes -- Embryonic stem cell test / Sjors H.W. Schulpen and Aldert H. Piersma -- Zebrafish teratogenicity testing / Kimberly C. Brannen, Jeffrey H. Charlap, and Elise M. Lewis -- Frog embryo teratogenesis assay on Xenopus and predictivity compared with in vivo mammalian studies / Isabelle Leconte and Isabelle Mouche -- Rat whole embryo culture assay using the dysmorphology score system / Cindy Zhang, Julie Panzica-Kelly, and Karen Augustine-Rauch -- Toxicogenomic approaches in developmental toxicology testing / Joshua F. Robinson and Aldert H. Piersma -- Validation of alternative tests for developmental and reproductive toxicology testing : an ILSI Health and Environmental Sciences Institute perspective / James H. Kim -- Regulatory assessment of reproductive toxicology data / Elizabeth Davidson -- Hazard and risk assessment of teratogenic chemicals under REACH / Wiebke Prutner -- Reproductive toxicity risk assessment for pesticides / Beate Ulbrich -- Thalidomide disaster, lessons from the past / James E. Ridings.
  • 2006 CRCnetBASE
    Malcolm J. Dodd ; with a contribution from Karen Byrne.
  • 2012 Springer
    Peter L. Elkin, editor.
    Introduction / Peter L. Elkin and Mark Samuel Tuttle -- History of Terminology and Terminological Logics / Peter L. Elkin and Mark Samuel Tuttle -- Knowledge Representation and the Logical Basis of Ontology / Peter L. Elkin and Steven H. Brown -- Theoretical Foundations of Terminology / Peter L. Elkin -- Compositionality: An Implementation Guide / Peter L. Elkin and Steven H. Brown -- Interface Terminologies / S. Trent Rosenbloom -- Springer Terminology Related Standards Development / Peter L. Elkin -- Implementations of Terminology / Peter L. Elkin, Mark Samuel Tuttle, Marjorie Rallins, Jennifer Trajkovski and Elizabeth Lumakovska, et al. -- Terminological Systems / Peter L. Elkin and Mark Samuel Tuttle -- Conclusion / Peter L. Elkin and Mark Samuel Tuttle.
  • 2008 CRCnetBASE
    edited by Paul R. Viotti, Michael A. Opheim, Nicholas Bowen.
    Toward a comprehensive strategy for terrorism and homeland security / Paul R. Viotti -- The search for national and homeland security : an integrated grand strategy / Robert H. Dorff -- Assured vulnerability : homeland security and the cold war legacy of defenselessness / David Goldfischer -- Terrorism and deterrence by denial / James M. Smith and Brent J. Talbot -- The importance of multinational and transnational cooperation strategies for homeland security / Veronica M. Kitchen and Gregory J. Moore -- WMD terrorism : new threats, revised responses / Jeffrey A. Larsen and James J. Wirtz -- Nuclear and radioactive threats to homeland security : prevention and response / Fred L. Wehling and Jeremy Tamsett -- Comparative risk analysis : biological terrorism, pandemics, and other "forgotten" catastrophic disaster threats / Terrence M. O'Sullivan -- Homeland security strategy and policy choices : a local government perspective / Greg Moser -- Democracy, civil society and the damage-limitation component of strategy / Alexander C. Diener and Timothy W. Crawford -- Transportation as a component of homeland security strategy / Joseph S. Szyliowicz -- Redefining U.S. energy security in the twenty-first century / Kevin King -- Afterword: terrorism and securing the homeland / Michael A. Opheim and Nicholas H. Bowen.
  • 2007 CRCnetBASE
    Michael R. Ronczkowski.
  • 2008 CRCnetBASE
    Malcolm W. Nance.
    Section 1. Know the terrorist. Your mission : critical awareness -- Who they are : identify terrorist operatives -- Intelligence profiling suspected terrorists -- Terrorist training -- Terrorism 101 : why the terrorist chooses this path -- What terrorists believe -- Section 2. Identifying the terrorist group and its cells. Terrorist group organization -- The terrorist cell -- Terrorist strategies and target selection -- Section 3. Detection of key terrorist activities. Terrorist preparations for attack : safe houses, finances, and mobility -- The terrorist's tools : conventional weapons identification -- The terrorist's tools : nuclear, biological, chemical weapons and equipment identification -- Section 4. Predicting an attack. Terrorist surveillance techniques -- Detecting infiltration and special mission techniques -- The decision and attack sequence -- The basics of analyzing intelligence and predicting terrorism events -- Point of danger : law enforcement traffic stops and encountering terrorists -- Point of failure : terrorist operations and tactics -- Section 5. The new fields of terror. A primer on Al-Qaeda and the global extremist insurgency -- Suicide terrorism : tactics, equipment and management -- Terrorism and insurgency in the Iraq War (2003-2008) -- Section 6. Supplemental data, bibliography and appendices . Appendix A. Global terrorist groups -- Appendix B. Explosive components & ingredients checklists.
  • 2008
    Jack J. Kanski.
    Status: Not Checked OutLane Catalog Record
  • 2006
    Daniel Adam Kraut.
    Status: Not Checked OutLane Catalog Record
  • 2012 Cambridge
    edited by Eberhard Nieschlag, Hermann M. Behre ; associate editor, Susan Nieschlag.
    1. The medical and cultural history of testosterone and the testes / Eberhard Nieschlag and Susan Nieschlag -- 2. Testosterone: biosynthesis, transport, metabolism and (non-genomic) actions / C. Marc Luetjens and Gerhard F. Weinbauer -- 3. Pathophysiology of the androgen receptor / Olaf Hiort, R. Werner and Michael Zitzmann -- 4. Methodology for measuring testosterone, DHT and SHBG in a clinical setting / Manuela Simoni, Flaminia Fanelli, Laura Roli and Uberto Pagotto -- 5. The behavioral correlates of testosterone / John Bancroft -- 6. The role of testosterone in spermatogenesis / Liza O'Donnell and Robert I. McLachlan -- 7. Androgens and hair: a biological paradox with clinical consequences / Valerie Anne Randall -- 8. Testosterone and bone / Dirk Vanderschueren, Mieke Sinnesael, E. Gielen, F. Claessens and S. Boonen; 9. Androgens effects on the skeletal muscle Shalender Bhasin, Ravi Jasuja, Carlo Serra, Rajan Singh, Thomas W. Storer, Wen Guo, Thomas G. Travison and Shezad Basaria; 10. Testosterone and cardiovascular disease Kevin S. Channer and T. Hugh Jones -- 11. Testosterone, obesity, diabetes and the metabolic syndrome / T. Hugh Jones and Kevin S. Channer -- 12. Testosterone and erection / Mario Maggi and Hermann M. Behre -- 13. Testosterone and the prostate / John T. Isaacs and Samuel R. Denmeade; 14. Clinical use of testosterone in hypogonadism and other conditions Eberhard Nieschlag and Hermann M. Behre; 15. Testosterone preparations for clinical use in males Hermann M. Behre and Eberhard Nieschlag; 16. Androgens in male senescence Jean-Marc Kaufman, Guy T'Sojen and Alex Verleulen -- 17. Androgen therapy in non-gonadal disease / David J. Handelsman -- 18. Review of guidelines on diagnosis and treatment of testosterone deficiency / Ronald S. Swerdloff and Christina C.L. Wang -- 19. Pathophysiology of estrogen action in men Vincenzo Rochira, Daniele Santi and Cesare Carani; 20. Dehydroepiandrosterone (DHEA) and androstenedione Bruno Allolio, Wiebke Arlt and Stefanie Hahner; 21. The state-of-the-art in the development of selective androgen receptor modulators (SARMs) / Ravi Jasuja, M. Zacharov and Shalender Bhasin -- 22. The essential role of testosterone in hormonal male contraception / Eberhard Nieschlag and Hermann M. Behre -- 23. Testosterone use in women / Susan R. Davis -- 24. Detection of illegal use of androgens and SARMs / Wilhelm Scha;nzer and Mario Thevis -- 25. Clinical effects of doping with anabolic steroids / Elena Vorona and Eberhard Nieschlag -- Index.
  • 2013 Springer
    Lee B. Smith, Rod T. Mitchell, Iain J. McEwan.
    This volume provides a brief resume of the history of testosterone research, from the early pioneers through to the most recent advances in the field. We discover how steroid hormones were first identified and how testosterone was shown to be essential for male development. Moving forward we explore how and where testosterone is produced, and how the body controls testosterone production. We then investigate the impact testosterone has on different body systems both during their development and function, and how perturbation of testosterone action is associated with disease. We complete our story with an exploration of the emerging roles of testosterone in clinical therapy, and the future potential for manipulation of the testosterone signaling system for human health benefit.
  • 2006
    Judy Thornton Stark.
    Status: Not Checked OutLane Catalog Record
  • 2010 Thieme eNeurosurgery
    [edited by] Shokei Yamada.
    Introduction to the tethered cord syndrome / Shokei Yamada -- Normal spinal cord development and the embryogenesis of spinal cord tethering malformations / Mark S. Dias and Elias B. Rizk -- Pathophysiology of the tethered cord syndrome / Shokei Yamada ... [et al.] -- Neurologic assessment of tethered spinal cord / Sanford Schneider -- Imaging of tethered spinal cord / David B. Hinshaw ... [et al.] -- Ultrasonographic evaluation of tethered cord syndrome / Marvin D. Nelson Jr -- Urological aspect of tethered cord syndrome I : lower urinary tract dysfunction in tethered cord syndrome / H. Roger Hadley ... [et al.] -- Urological aspect of tethered cord syndrome II : clinical experience in urological involvement with tethered cord syndrome / Antoine E. Khoury -- The cervical tethered spinal cord / Kenji Muro, Arthur J. DiPatri Jr., and David G. McLone -- Indication and treatment of tethered spinal cord / James M. Drake and Harold J. Hoffman. Tethered cord syndrome associated with myelomeningoceles and lipomyelomeningoceles / Shokei Yamada ... [et al.] -- The role of folate supplementation in spina bifida occulta / Elias Rizk and Bermans J. Iskandar -- In utero repair of myelomeningoceles / Nalin Gupta -- Epidermoid and dermoid tumors associated with tethered cord syndrome / David S. Knierim, Daniel J. Won, and Shokei Yamada -- Tethered cord syndrome in adult and late-teenage patients without neural spinal dysraphism / Shokei Yamada ... [et al.] -- Tethered cord syndrome in adults with spina bifida occulta / Sharad Rajpal, Samir B. Lapsiwala, and Bermans J. Iskandar -- The normal position of the conus medullaris does not exclude a tethered spinal cord / R. Shane Tubbs and W. Jerry Oakes -- Anomalies of the spinal cord length and filum thickness / Shokei Yamada, Javed Siddiqi, and Shoko M. Yamada -- Intraoperative neurophysiological monitoring of the lower sacral nerve roots and spinal cord / Dachling Pang -- Clinical neurophysiology of tethered cord syndrome and other dysraphic syndromes / Robin L. Gilmore, Sun Ik Lee, and John Walsh -- Conservative versus surgical treatment and prognostic evaluation for tethered cord syndrome / Shokei Yamada ... [et al.].
  • 2010
    Eric Joseph Espinosa.
    Status: Not Checked OutLane Catalog Record
  • 2006
    first draft prepared by Peter Watts.
  • 2012 ScienceDirect
    edited by Kathleen Collins.
  • 2010
    Nicole Hanick Kattah.
    Antigen-specific CD4+ T cells have been implicated in the autoimmune disease systemic lupus erythematosus (SLE), yet little is known about the function of these T cells or the precise peptide antigens that they recognize. We hypothesized that antigen-specific CD4+ T cells contribute to lupus pathology through two mechanisms: (1) by providing help to B cells for pathogenic autoantibody production, and (2) by directly promoting inflammation through the secretion of proinflammatory cytokines. We tested these two hypotheses by generating a series of MHC class II tetramers of I-Ek containing peptides from the spliceosomal protein U1-70. These tetramers specifically stained distinct CD4+ T cell populations in MRL/lpr mice. Using these reagents, we demonstrated that CD4+ T cells specific for U1-70 (131-150):I-Ek correlated with disease and with anti-U1-70 autoantibody production, expressed ROR[lowercase gamma]t and Tbet, and produced IFN[lowercase gamma] and IL-17A in an I-Ek-dependent manner. We confirmed our findings from mice in human patients with SLE and mixed connective tissue disease (MCTD). U1-70 specific CD4+ T cells obtained from peripheral blood mononuclear cells (PBMCs) of patients with SLE produced IFN[lowercase gamma] in all 5 patients tested and IL-17A in 1 out of 2 patients whose serum contained RNP autoantibodies. These data support the hypotheses that antigen-specific T cells recognize the same autoantigens as B cells, and that they produce proinflammatory cytokines. These studies represent the first reported tetramers for studying antigen-specific T cells in a mouse model of lupus, and demonstrate an antigen-specific source of IL-17A in human autoimmune disease.
  • 2009 Springer
    [edited by] Martin J. Warren, Alison G. Smith.
    An historical introduction to porphyrin and chlorophyll synthesis / Michael R. Moore -- Biosynthesis of 5-aminolevulinic acid / Dieter Jahn and Dirk W. Heinz -- 5-aminolaevulinic acid dehydratase, porphobilinogen deaminase and uroporphyrinogen III synthase / Heidi L. Schubert, Peter T. Erskine and Jonathan B. Cooper -- Transformation of uroporphyrinogen III into protohaem / Johanna E. Cornah and Alison G. Smith -- Inherited disorders of haem synthesis: the human porphyrias / Michael N. Badminton and George H. Elder -- Heme degradation: mechanistic and physiological implications / Angela Wilks -- Regulation of mammalian heme biosynthesis / Amy E. Medlock and Harry A. Dailey -- Tetrapyrroles in photodynamic therapy / David I. Vernon and Ian Walker -- Heme transport and incorporation into proteins / Linda Thöny-Meyer -- Heme and hemoproteins / Andrew W. Munro ... [et al.] -- Novel heme-protein interactions: some more radical than others / Ann Smith -- Synthesis and role of bilins in photosynthetic organisms / Nicole Frankenberg-Dinkel and Matthew J. Terry -- Phytochromes: bilin-linked photoreceptors in bacteria and plants / Matthew J. Terry and Alex C. McCormac -- Biosynthesis of chlorophyll and bacteriochlorophyll / Derren J. Heyes and C. Neil Hunter -- Regulation of tetrapyrrole synthesis in higher plants / Matthew J. Terry and Alison G. Smith -- Regulation of the late steps of chlorophyll biosynthesis / Wolfhart Rudiger -- Chlorophyll breakdown / Bernhard Kräutler -- Vitamin B12: biosynthesis of the corrin ring / Ross M. Graham, Evelyne Deery and Martin J. Warren -- Conversion of cobinamide into coenzyme B12 / Jorge C. Escalante-Semerena ... [et al.] -- The regulation of cobalamin biosynthesis / Jeffrey G. Lawrence -- Coenzyme B12-catalyzed radical isomerizations / Dominique Padovani and Ruma Banerjee -- Biosynthesis of siroheme and coenzyme F430 / Martin J. Warren, Evelyne Deery and Ruth-Sarah Rose -- Role of coenzyme F430 in methanogenesis / Evert C. Duin -- The role of siroheme in sulfite and nitrite reductases / M. Elizabeth Stroupe and Elizabeth D. Getzoff -- The role of heme d1 in denitrification / Stuart J. Ferguson.
  • 2013 Springer
    Fedor Berditchevski, Eric Rubinstein, editors.
    Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in which the role of tetraspanins have been established and also covers the molecular evolution of the tetraspanin superfamily and structural aspects of the organisation of tetraspanin microdomains.
  • 2015 Springer
    Massimo Romanò ; with contributions by Roberta Bertona.
    This book combines clear explanatory text with a wealth of images of ECG recordings in order to provide an accessible, up-to-date source of information and guide to interpretation for all professionals seeking to increase their expertise in electrocardiography. ECG results are presented and discussed for a wide range of conditions, including all forms of arrhythmia, Wolff-Parkinson-White syndrome, bundle branch blocks, ischemic cardiomyopathy, atrial and ventricular enlargement, pericardial and myocardial diseases, diseases of the pulmonary circulation, and post pacemaker implantation. Normal ECG findings are fully described, and helpful introductory information is included on the principles of electrophysiology. The practically oriented text accompanying the ECG recordings covers both electrophysiological and clinical aspects. More than 100 years after its first use by Willem Einthoven, electrocardiography continues to be the first diagnostic tool applied in most cardiac patients. This text atlas provides a sound basis for the correct ECG interpretation essential for appropriate patient management.
  • 2010
    Yael Garten.
    Pharmacogenomics is the study of how variation in the human genome impacts drug response in patients. It is a major driving force of "personalized medicine" in which drug choice and dosing decisions are informed by individual information such as DNA genotype. The field of pharmacogenomics is in an era of explosive growth; massive amounts of data are being collected and knowledge discovered, which promises to push forward the reality of individualized clinical care. However, this large amount of data is dispersed in many journals in the scientific literature and pharmacogenomic findings are discussed in a variety of non-standardized ways. It is thus challenging to identify important associations between drugs and molecular entities, particularly genes and gene variants. Thus, these critical connections are not easily available to investigators or clinicians who wish to survey the state of knowledge for any particular gene, drug, disease or variant. Manual efforts have attempted to catalog this information, however the rapid expansion of pharmacogenomic literature has made this approach infeasible. Natural Language Processing and text mining techniques allow us to convert free-style text to a computable, searchable format in which pharmacogenomic concepts such as genes, drugs, polymorphisms, and diseases are identified, and important links between these concepts are recorded. My dissertation describes novel computational methods to extract and predict pharmacogenomic relationships from text. In one project, we extract pharmacogenomic relationships from the primary literature using text-mining. We process information at the fine-grained sentence level using full text when available. In a second project, we investigate the use of these extracted relationships in place of manually curated relationships as input into an algorithm that predicts pharmacogenes for a drug of interest. We show that for this application we can perform as well with text-mined relationships as with manually curated information. This approach holds great promise as it is cheaper, faster, and more scalable than manual curation. Our method provides us with interesting drug-gene relationship predictions that warrant further experimental investigation. In the third project, we describe knowledge inference in the context of pharmacogenomic relationships. Using cutting-edge natural language processing tools and automated reasoning, we create a rich semantic network of 40,000 pharmacogenomic relationships distilled from 17 million Medline abstracts. This network connects over 200 entity types with clear semantics using more than 70 unique types of relationships. We use this network to create collections of precise and specific types of knowledge, and infer relationships not stated explicitly in the text but rather inferred from the large number of related sentences found in the literature. This is exciting because it demonstrates that we are able to overcome the heterogeneity of written language and infer the correct semantics of the relationship described by authors. Finally, we can use this network to identify conflicting facts described in the literature, to study change in language use over time, and to predict drug-drug interactions. These achievements provide us with new ways of interacting with the literature and the knowledge embedded within it, and help ensure that we do not bury the knowledge embodied in the publications, but rather connect the often fragmented and disconnected pieces of knowledge spread across millions of articles in hundreds of journals. We are thereby brought one step closer to the realization of personalized medicine and ensure that as scientists, we continue to build on the knowledge discovered by past generations and truly to stand on the shoulders of giants.
  • 1978-
    Alfred Vogt.
    Status: Not Checked OutLane Catalog Record
    v. 1. Principles and methods. Cornea and anterior chamber -- v. 2. Lens and zonule -- v.3. Iris, vitreous body, conjunctiva.
  • 2015 Springer
    Nady el-Guebaly, Giuseppe Carrà, Marc Galanter, editors.
  • 2015 ClinicalKey
    edited by Peter Cameron, George Jelinek, Anne-Maree Kelly, Anthony Brown, Mark Little.
    Now fully revised and updated, Textbook of Adult Emergency Medicine provides clear and consistent coverage of this rapidly evolving specialty. Building on the success of previous editions, it covers all the major topics that present to the trainee doctor in the emergency department. It will also prove invaluable to the range of other professionals working in this setting - including nurse specialists and paramedics - who require concise, highly practical guidance, incorporating latest best practice and current guidelines. For the first time this edition now comes with a complete and enhanced electronic version, providing a richer learning experience and making rapid reference easier than ever before, anytime, anywhere. Updates throughout reflect latest practice developments, curricula requirements and essential guidelines Key point boxes highlight topic 'essentials' as well as controversial areas of treatment An expanded list of leading international contributors ensures comprehensive coverage and maximizes worldwide relevance New and enhanced coverage of important and topical areas - including latest imaging in emergency medicine; organ donation; massive transfusion protocols; medico legal issues; patient safety and quality measures All new accompanying electronic version, including procedure videos and self-assessment materials to check your understanding and aid exam preparation.
  • 2010 Springer
    Miranda A. Farage, Kenneth W. Miller, Howard I. Maibach, editors.
  • 2012 Springer
    Enrique Zudaire, Frank Cuttitta, editors.
    Angiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis. A substantial increase in the research effort over the past decade has deepened our understanding of the basic mechanisms underlying angiogenesis and lymphangiogenesis, promoting the development of promising therapeutics for the clinical management of vascular-related diseases.
  • 2012 CRCnetBASE
    edited by David K. Gardner, Ariel Weissman, Colin M. Howles, Zeev Shoham.
  • 2012 CRCnetBASE
    edited by David K. Gardner, Ariel Weissman, Colin M. Howles, Zeev Shoham.
  • 2011
    edited by Thomas M. Devlin.
    Status: Not Checked OutLane Catalog Record
    Part I: Structure of macromolecules -- 1. Eukaryotic Cell Structure -- 2. DNA and RNA: Composition and Structure -- 3. Proteins I: Composition and Structure -- Part II: Transmission of information -- 4. DNA Replication, Recombination, and Repair -- 5. RNA: Transcription and RNA Processing -- 6. Protein Synthesis: Translation and Posttranslational Modifications -- 7. Recombinant DNA and Biotechnology -- 8. Regulation of Gene Expression -- Part III: Functions of proteins -- 9. Proteins II: Structure-Function Relationships in Protein Families -- 10. Enzymes: Classification, Kinetics, and Control -- 11. The Cytochromes P450 and Nitric Oxide Synthases -- 12. Biological Membranes: Structure, Receptors, and Solute Transport -- 13. Fundamentals of Signal Transduction -- Part IV: Metabolic pathways and their control -- 14. Bioenergetics, Mitochondria, and Oxidative Metabolism -- 15. Carbohydrate Metabolism I: Major Metabolic Pathways and Their Control -- 16. Carbohydrate Metabolism II: Special Pathways and Glycoconjugates -- 17. Lipid Metabolism I: Synthesis, Storage, and Utilization of Fatty Acids and Triacylglycerols -- 18. Lipid Metabolism II: Pathways of Metabolism of Special Lipids -- 19. Amino Acid and Heme Metabolism -- 20. Purine and Pyrimidine Nucleotide Metabolism -- 21. Metabolic Interrelationships -- 22. Biochemistry of Hormones -- Part V: Physiological processes -- 23. Molecular Cell Biology -- 24. Cell Cycle, Programmed Cell Death, and Cancer -- 25. Digestion and Absorption of Basic Nutritional Constituents -- 26. Vitamins and Minerals: Requirements and Function -- 27. Macronutrients: Metabolic Effects and Health Implications -- Appendix: Review of Organic Chemistry -- Glossary -- Index.
  • 2006
    edited by Thomas M. Devlin.
    Status: Not Checked OutLane Catalog Record
  • 2006
    edited by Gianni Bonadonna, Gabriel N. Hortobagyi, Pinuccia Valagussa.
    Status: Not Checked OutLane Catalog Record
  • 2008
    edited by Hans-Olov Adami, David Hunter, Dimitrios Trichopoulos ; with an introductory chapter by Brian MacMahon.
    Status: Not Checked OutLane Catalog Record
    Part I. Background -- Accomplishments in cancer epidemiology / Brian MacMahon -- Measures and estimates of cancer burden / Pagona Lagiou, Johanna Adami, and Dimitrios Trichopoulos -- The origin of cancer /Jeffrey Ecsedy and David Hunter -- Genetic epidemiology of cancer / Christopher Haiman and David Hunter -- Biomarkers in cancer epidemiology / Paolo Boffetta and Dimitrios Trichopoulos -- Concepts in cancer epidemiology and etiology / Pagona Lagiou, Dimitrios Trichopoulos, and Hans-Olov Adami -- Part II. Cancer epidemiology by site-specific cancers -- Oral and pharyngeal cancer / Paul Brennan, Lorelei Mucci, and Hans-Olov Adami -- Nasopharyngeal carcinoma / Ellen Chang and Hans-Olov Adami -- Esophageal cancer / Olof Nyrén and Hans-Olov Adami -- Stomach cancer / Olof Nyrén and Hans-Olov Adami -- Colorectal cancer / John D. Potter and David Hunter -- Cancer of the liver and biliary tract / Sherri Stuver and Dimitrios Trichopoulos -- Pancreatic cancer / Anders Ekbom and Dimitrios Trichopoulos -- Cancer of the lung, larynx, and pleura / Paolo Boffetta and Dimitrios Trichopoulos -- Skin cancer / Adèle Green, Jolieke van der Pols, and David Hunter -- Breast cancer / Susan Hankinson, Rulla Tamimi, and David Hunter -- Cervical cancer / Nathalie Ylitalo, Sherri Stuver, and Hans-Olov Adami -- Endometrial cancer / Immaculata DeVivo, Ingemar Persson, and Hans-Olov Adami -- Ovarian cancer / Penelope Webb, Dorota Gertig, and David Hunter -- Prostate cancer / Lorelei A. Mucci, Lisa B. Signorello, and Hans-Olov Adami -- Testicular cancer / Lorenzo Richiardi, Rulla Tamimi, and Hans-Olov Adami -- Urinary bladder cancer / Manolis Kogevinas, Montserrat Garcia-Closas, and Dimitrios Trichopoulos -- Kidney cancer / Eunyoung Cho, Per Lindblad, and Hans-Olov Adami -- Brain cancer / David A. Savitz and Dimitrios Trichopoulos -- Thyroid cancer / Per Hall and Hans-Olov Adami -- Hodgkin lymphoma / Mads Melbye, Henrik Hjalgrim, and Hans-Olov Adami -- Non-hodgkin lymphoma / Mads Melbye, Karin Ekström Smedby, and Dimitrios Trichopoulos -- Leukemias / Eleni Petridou, Apostolos Pourtsidis, and Dimitrios Trichopoulos.
  • 2014 Springer
    edited by Craig A. Thompson.
    Catheter-based interventions have evolved to address a variety of needs through innovation and clinical evidence.The field of interventional cardiology and interventional vascular medicine now comprises the dominant diagnostic and therapeutic field within cardiovascular medicine, and continues to grow in terms of patients managed and physicians trained. Given the vast expansion of technologies, techniques, and the clinical evidence base, it can be challenging for the practicing clinician, fellow-in-training, or technology developer to maintain general knowledge of the interventional cardiovascular field.The Textbook of Cardiovascular Intervention is intended to provide a practical, comprehensive and compact text on interventional cardiology for the current, rapidly evolving practice environment. It will appeal to fellows, residents and physicians in cardiology, interventional cardiology, cardiothoracic and vascular surgery, vascularand endovascular medicine, neurointerventional radiology and surgery, emergency medicine and intensive care.
  • 2002 Ovid
    edited by Eric J. Topol.
  • 2007 Ovid
    editor, Eric J. Topol ; associate editors, Robert M. Califf ... [et al.].
    Atherosclerotic biology and epidemiology of disease -- Diet and nutritional issues -- Obesity and metabolic syndrome -- Diabetes -- Lipid disorders -- Exercise and physical activity -- Hypertension: context and management -- Smoking -- Estrogen, female gender, and heart disease -- Ethanol and the heart -- Other risk factors for coronary artery disease -- Behavioral cardiology and heart disease -- Cardiac rehabilitation and secondary prevention -- An integrated approach to risk factor modification -- The history -- Physical examination -- Chronic stable coronary disease -- Unstable angina: ischemic syndromes -- Acute myocardial infarction: early diagnosis and management -- Acute myocardial infarction: complications -- Post-Myocardial infarction management -- Mitral valve disease -- Aortic valve disease -- Acquired tricuspid and pulmonary valve disease -- Prosthetic valve disease -- Infective endocarditis -- Diseases of the pericardium, restrictive cardiomyopathy, and diastolic dysfunction -- Pulmonary hypertension -- Hypertrophic cardiomyopathy -- Congenital heart disease -- The heart and pregnancy -- Women and heart disease -- The elderly and aging -- End-of-life care -- The heart and other organ systems -- Endocrine systems and the heart -- Hematologic disorders and the heart -- The heart and the renal system -- Cardiac manifestations of selected neurologic disorders -- Cardiovascular manifestations of rheumatic diseases -- The heart and infectious diseases -- Substance abuse and the heart -- The athlete's heart -- Cardiac trauma -- Cardiac tumors -- Clinical pharmacology for the cardiologist -- Perioperative anesthetic considerations in noncardiac surgery for those at high risk of cardiovascular disease -- Medical economics in cardiovascular medicine -- Considerations in the design, conduct, and interpretation of quantitative clinical evidence -- Databases in cardiology -- Quality of care and medical errors in cardiovascular disease -- Principles of imaging -- Plain film examination of the chest -- Exercise electrocardiography -- Transthoracic echocardiography -- Stress echocardiography -- Doppler echocardiography -- Transesophageal echocardiography -- Imaging techniques in nuclear cardiology -- Cardiovascular magnetic resonance imaging -- Positron emission tomography -- Computed tomography of the heart -- Mechanisms of cardiac arrhythmias -- Genetics of arrhythmias -- Electrocardiography -- Ambulatory and signal-averaged electrocardiography and t-wave alternans -- Electrophysiologic testing -- Bradycardias: sinus nodal dysfunction and atrioventricular conduction disturbances -- Atrial fibrillation -- Atrial flutter -- Atrioventricular nodal-dependent tachycardias and preexcitation -- Ventricular tachycardia -- Sudden cardiac death and implantable cardioverter-defibrillators -- Sudden cardiac death in the young: the impact of inherited cardiovascular disease -- Cardiopulmonary resuscitation -- Arrhythmias in congenital heart disease -- Syncope -- Antiarrhythmic drugs -- Catheter ablation therapy for arrhythmias -- Cardiac pacemakers -- Left ventricular dyssynchrony and cardiac resynchronization therapy-- Coronary angiography -- Cardiac catheterization and hemodynamic assessment -- Percutaneous coronary intervention -- Percutaneous cardiac procedures -- Coronary artery bypass surgery -- Approaches to the patient with prior bypass surgery -- Percutaneous valve dilatations -- Catheter interventions in congenital heart disease -- Global pandemic of heart failure -- Pathophysiology of the heart failure clinical syndrome -- Acute heart failure -- Chronic heart failure management -- Diagnosis and medical treatment of inflammatory cardiomyopathy -- Nonischemic cardiomyopathies -- Cardiac transplantation and mechanical circulatory support -- surgical approaches for heart failure -- Prevention of heart failure -- General techniques in molecular cardiology -- Molecular genetics -- Genetic factors in atherosclerosis -- Genetic studies of myocardial and vascular disease -- Gene therapy -- Myocyte structure and function -- Signal transduction pathways of the heart -- Molecular basis of heart development -- Stem cell therapy for ischemic heart disease -- The biology of restenosis -- Therapeutic angiogenesis -- Diseases of the pulmonary vasculature -- Diseases of the aorta -- Noninvasive assessment of peripheral vascular disease -- Cerebrovascular disease -- Disease of peripheral vessels -- Renal artery disease -- Venous thromboembolism.
  • 2013 ClinicalKey
    Catherine M. Otto.
    This 5th Edition enables you to use echocardiography to its fullest potential in your initial diagnosis, decision making, and clinical management of patients with a wide range of heart diseases. World-renowned cardiologist Dr. Catherine M. Otto helps you master what you need to know to obtain the detailed anatomic and physiologic information that can be gained from the full range of echo techniques, from basic to advanced. Acquire a solid foundation in the essentials of advanced echocardiography techniques such as contrast echo, 3D echo, myocardial mechanics, and intraoperative transesophageal echocardiography. Fully understand the use of echocardiography and its outcomes with key points that identify the must-know elements in every chapter, and state-of-the-art echo images complemented by full-color comparative drawings of heart structures. Familiarize yourself with new ASE recommendations for echocardiographic assessment of the right heart and 3D echocardiography, including updated tables of normal measurements.
  • 2013 Cambridge
    edited by Kevin Coward, Dagan Wells.
    "The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook - inspired by the postgraduate degree program at the University of Oxford - guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology"--Provided by publisher.
  • 2008 ClinicalKey
    Michael Ragosta.
    Introduction to hemodynamic assessment in the cardiac catheterization laboratory / Michael Ragosta -- Normal waveforms, artifacts, and pitfalls / Michael Ragosta -- Cardiac outputs and shunts / Vishal Aurora -- Mitral valve disorders / Michael Ragosta -- Aortic valve disease / Michael Ragosta -- Hypertrophic cardiomyopathy and related conditions / Michael Ragosta -- Right-sided heart disorders: hemodynamics of the tricuspid and pulmonic valves and pulmonary hypertension / Michael Ragosta -- Pericardial disease and restrictive cardiomyopathy / Michael Ragosta -- Shock, heart failure, and related disorders / Michael Ragosta -- Complications of acute myocardial infarction / Brandon Brown -- Congenital heart disease / Rajan A.G. Patel and D. Scott Lim -- Coronary hemodynamics / Michael Ragosta -- Advanced hemodynamic assessment of ventricular function / D. Scott Lim and Howard P. Gutgesell -- Miscellaneous hemodynamic conditions / Michael Ragosta.
    Also available: Print – 2008
  • 2007 ClinicalKey
    [edited by] Christopher G. Goetz.
    Also available: Print – 2007
  • 2012 Springer
    [edited by] Abdelaziz Y. Elzouki ; Harb A. Harfi, Hisham M. Nazer, F. Bruder Stapleton.
    V. 1, section 1. Genetic disorders / Bruce R. Korf ; section 2. Neonatology / Martin Keszler ; section 3. Inborn errors of metabolism / Pinar T. Ozand ; section 4. Developmental, learning and behavioral disorders / Pamela High and Yvette Yatchmink -- v. 2, section 5. Pediatric nutrition / Hisham M. Nazer ; section 6. Infectious diseases / Richard J. Whitley ; section 7. Primary immunodeficiency disorders / Harb A. Harfi ; section 8. Allergic disorders / Harb A. Harfi -- v. 3, section 9. Disorders of the skin / Zbigniew Ruszczak ; section 10. Rheumatology / Alberto Martini ; section 11. Oral and craniofacial disorders / J. Burton Douglass ; section 12. Gastrointestinal and liver disorders / Hisham M. Nazer -- v. 4, section 13. Respiratory disorders / Gabriel G. Haddad ; section 14. Cardiology / Mark B. Lewin ; section 15. Critical care / Abdul-Rahman M. Abu-Taleb and Peter N. Cox ; section 16. Pediatric burns / Fuad Hashem ; section 17. Pediatric poisoning / Khaled M. Al-Haidari and Nada S. Al-Qadheeb ; section 18. Disturbances in acid-base and electrolytes disorders / F. Bruder Stapleton ; section 19. Kidney and urinary tract disorders / F. Bruder Stapleton -- v. 5, section 19. Kidney and urinary tract disorders / F. Bruder Stapleton ; section 20. Blood diseases / Michael Recht ; section 21. Pediatric oncology / H. Stacy Nicholson ; section 22. Neurology / Generoso G. Gascon -- v. 6, section 22. Neurology / Generoso G. Gascon ; section 23. Endocrine disorders / Khalid Hussain ; section 24. Adolescent medicine / Leslie R. Walker ; section 25. Pediatric orthopedics / Craig P. Eberson ; section 26. Pediatric otolaryngology / Mohamed O. Abuzeid ; section 27. Pediatric ophthalmology / Selwa A.F. Al-Hazzaa ; section 28. Pediatric surgery / Thomas F. Tracy ; section 29. Drug dosing in pediatrics / Kristine A. Parbuoni.
  • 2011 ClinicalKey
    [edited by] Jean-Louis Vincent [and others].
    This reference - acclaimed for its success in bridging the gap between medical and surgical critical care - now features an even stronger focus on patient outcomes, equipping you with the proven, evidence-based guidance you need to successfully overcome a full range of practice challenges. Inside, you'll find totally updated coverage of vital topics, such as coagulation and apoptosis in certain critical care illnesses, such as acute lung injury and adult respiratory distress syndrome; sepsis and other serious infectious diseases; specific organ dysfunction and failure; and many other vital topics. Effectively apply the latest techniques and approaches with totally updated coverage of the importance of coagulation and apoptosis in certain critical care illnesses, such as acute lung injury and adult respiratory distress syndrome; sepsis and other serious infectious diseases; specific organ dysfunction and failure; and many other vital topics.
  • 2012 ClinicalKey
    Sandra L. Hagen-Ansert.
    Synopsis: Stay up to date with the rapidly changing field of medical sonography! Heavily illustrated and extensively updated to reflect the latest developments in the field, Textbook of Diagnostic Sonography, 7th Edition equips you with an in-depth understanding of general/abdominal and obstetric/gynecologic sonography, the two primary divisions of sonography, as well as vascular sonography and echocardiography. Each chapter includes patient history, normal anatomy (including cross-sectional anatomy), ultrasound techniques, pathology, and related laboratory findings, giving you comprehensive insight drawn from the most current, complete information available. Full-color presentation enhances your learning experience with vibrantly detailed images. Pathology tables give you quick access to clinical findings, laboratory findings, sonography findings, and differential considerations. Sonographic Findings highlight key clinical information. Key terms and chapter objectives help you study more efficiently. Review questions on a companion Evolve website reinforce your understanding of essential concepts. New chapters detail the latest clinically relevant content in the areas of: Essentials of Patient Care for the Sonographer; Artifacts in Image Acquisition; Understanding Other Imaging Modalities; Ergonomics and Musculoskeletal Issues in Sonography; 3D and 4D Evaluation of Fetal Anomalies; More than 700 new images (350 in color) clarify complex anatomic concepts. Extensive content updates reflect important changes in urinary, liver, musculoskeletal, breast, cerebrovascular, gynecological, and obstetric sonography.
  • v. 1-2, 2006.
    Sandra L. Hagen-Ansert.
    Status: Not Checked OutLane Catalog Record
  • Google Books
    Penrose, Charles B.
    Also available: Print – 1897-
  • 2015 ClinicalKey
    [edited by] Robert E. Rakel, David P. Rakel.
    This ninth edition of the Textbook of Family Medicine, edited by Drs. Robert E. Rakel and David P. Rakel, remains your #1 choice for complete guidance on the principles of family medicine, primary care in the community, and all aspects of clinical practice. Ideal for both residents and practicing physicians, this medical reference book includes evidence-based, practical information to optimize patient care and prepare you for the ABFM exam. A clean, quick-reference layout makes it easy for you to put information to work immediately in your practice.
  • 2009
    Ian R. McWhinney, Thomas Freeman.
    Status: Not Checked OutLane Catalog Record
    The origins of family medicine -- Principles of family medicine -- Illness in the community -- A profile of family practice -- Philosophical and scientific foundations of family medicine -- Illness, suffering, and healing -- Doctor-patient communication -- Clinical method -- The enhancement of health and the prevention of disease -- The family in health and disease -- Acute sore throat -- Headache -- Fatigue -- Hypertension -- Diabetes -- Home care -- Records -- Consultation and referral -- The health professions -- The community service network -- Alternative or complementary medicine -- Practice management -- Continuing self-education -- Research in family practice.
  • 2007
    [edited by] Robert E. Rakel.
    Status: Not Checked OutLane Catalog Record
  • 2003 Ovid
    editor, Tadataka Yamada ; associate editors, David H. Alpers ... [et al.].
    Also available: Print – v. 1-2, 2003.
  • v.1-2, 2015 ClinicalKey
    [edited by] Richard M. Gore, Marc S. Levine.
    Imaging contrast agents and pharmacoradiology -- Barium studies : single and double contrast -- Pictorial glossary of double-contrast radiology -- Ultrasound of the hollow viscera -- Multidetector computed tomography of the gastrointestinal tract : principles of interpretation -- Magnetic resonance imaging of the hollow viscera -- Positron emission tomography and computed tomography of the hollow viscera -- Angiography and interventional radiology of the hollow viscera -- Abdominal computed tomography angiography -- Magnetic resonance angiography of the mesenteric vasculature -- Abdomen : normal anatomy and examination techniques -- Gas and soft tissue abnormalities -- Abdominal calcifications -- Pharynx : normal anatomy and examination techniques -- Abnormalities of pharyngeal function -- Structural abnormalities of the pharynx -- Barium studies of the upper gastrointestinal tract -- Motility disorders of the esophagus -- Gastroesophageal reflux disease -- Infectious esophagitis -- Other esophagitides -- Benign tumors of the esophagus -- Carcinoma of the esophagus -- Other malignant tumors of the esophagus -- Miscellaneous abnormalities of the esophagus -- Abnormalities of the gastroesophageal junction -- Postoperative esophagus -- Esophagus : differential diagnosis -- Peptic ulcers -- Inflammatory conditions of the stomach and duodenum -- Benign tumors of the stomach and duodenum -- Carcinoma of the stomach and duodenum -- Other malignant tumors of the stomach and duodenum -- Miscellaneous abnormalities of the stomach and duodenum -- Postoperative stomach and duodenum -- Stomach and duodenum : differential diagnosis -- Barium examinations of the small intestine -- Computed tomography enterography -- Computed tomography enteroclysis -- Magnetic resonance enterography -- Crohn's disease of the small bowel -- Inflammatory disorders of the small bowel other than Crohn's disease -- Malabsorption -- Benign tumors of the small bowel -- Malignant tumors of the small bowel -- Small bowel obstruction -- Vascular disorders of the small intestine -- Postoperative small bowel -- Miscellaneous abnormalities of the small bowel -- Small intestine : differential diagnosis -- Barium studies of the colon -- Functional imaging of anorectal and pelvic floor dysfunction -- Computed tomography colonography -- Magnetic resonance colonography -- Diverticular disease of the colon -- Diseases of the appendix -- Ulcerative and granulomatous colitis : idiopathic inflammatory bowel disease -- Other inflammatory conditions of the colon -- Polyps and colon cancer -- Other tumors of the colon -- Polyposis syndromes -- Miscellaneous abnormalities of the colon -- Postoperative colon -- Colon : differential diagnosis -- Computed tomography of the solid abdominal organs -- Ultrasound examination of the solid abdominal viscera -- Magnetic resonance imaging of the solid parenchymal organs -- Positron emission tomography/computed tomography of the solid parenchymal organs -- Diffusion-weighted imaging of the abdomen -- Perfusion computed tomography and magnetic resonance imaging in the abdomen and pelvis -- Techniques of percutaneous tissue acquisition -- Abdominal abscess -- Gallbladder and biliary tract : normal anatomy and examination techniques -- Endoscopic retrograde cholangiopancreatography -- Magnetic resonance cholangiopancreatography -- Anomalies and anatomic variants of the gallbladder and biliary tract -- Cholelithiasis, cholecystitis, choledocholithiasis, and hyperplastic cholecystoses -- Interventional radiology of the gallbladder and biliary tract -- Neoplasms of the gallbladder and biliary tract -- Inflammatory disorders of the biliary tract -- Postsurgical and traumatic lesions of the biliary tract -- Gallbladder and biliary tract : differential diagnosis -- Liver : normal anatomy and examination techniques -- Interventional radiology of the liver -- Anomalies and anatomic variants of the liver -- Benign tumors of the liver -- Malignant tumors of the liver -- Focal hepatic infections -- Diffuse liver disease -- Vascular disorders of the liver and splanchnic circulation -- Hepatic trauma, surgery, and liver-directed therapy -- Liver transplantation imaging -- Liver : differential diagnosis -- Pancreas : normal anatomy and examination techniques -- Interventional radiology of the pancreas -- Anomalies and anatomic variants of the pancreas -- Pancreatitis -- Pancreatic neoplasms -- Pancreatic trauma and surgery -- Pancreatic transplantation imaging -- Pancreas : differential diagnosis -- Spleen : normal anatomy and examination techniques -- Angiography and interventional radiology of the spleen -- Anomalies and anatomic variants of the spleen -- Benign and malignant lesions of the spleen -- Splenic trauma and surgery -- Spleen : differential diagnosis -- Anatomy and imaging of the peritoneum and retroperitoneum -- Pathways of abdominal and pelvic disease spread -- Ascites and peritoneal fluid collections -- Mesenteric and omental lesions -- Hernias and abdominal wall pathology -- Applied embryology of the gastrointestinal tract -- Neonatal gastrointestinal radiology -- Diseases of the pediatric esophagus -- Diseases of the pediatric stomach and duodenum -- Diseases of the pediatric small bowel -- Diseases of the pediatric colon -- Diseases of the pediatric gallbladder and biliary tract -- Diseases of the pediatric liver -- Diseases of the pediatric pancreas -- Diseases of the pediatric spleen -- Diseases of the pediatric abdominal wall, peritoneum, and mesentery -- The acute abdomen -- Gastrointestinal hemorrhage -- Abdominal trauma -- Monitoring gastrointestinal tumor response to therapy.
  • 2014 Springer
    Ali Alikhan, Jean-Marie Lachapelle, Howard I. Maibach, editors.
    Hand eczema is a major complaint worldwide and a frequent occupational disorder. This book provides a comprehensive and detailed overview of the classification, etiology, diagnosis, prevention, and therapy of hand eczema. It is innovative, up to date, and practical. The links with particular occupations are explained, the various diagnostic tests are presented, and the role of different topical and systemic treatments is clearly described. The authors are world leaders in the field. The Textbook of Hand Eczema reflects a new era in hand dermatitis and will be invaluable for all who deal with the condition in their clinical practice.
  • 2017 ClinicalKey
    Leslie P. Gartner.
    Introduction to histology and basic histological techniques -- Cytoplasm -- Nucleus -- Extracellular matrix -- Epithelium and glands -- Connective tissue -- Cartilage and bone -- Muscle -- Nervous tissue -- Blood and hemopoiesis -- Circulatory system -- Lymphoid (immune) system -- Endocrine system -- Integument -- Respiratory system -- Digestive system : oral cavity -- Digestive system : alimentary canal -- Digestive system : glands -- Urinary system -- Female reproductive system -- Male reproductive system -- Special senses.
  • 2014 Cambridge
    edited by Karen Sermon, Professor, Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Brussels, Belgium, Stéphane Viville, professor, Institut de Génétique et de Biologie Móleculaire et Cellulaire (IGBMC), Institut National de Santé et de Recherche Médicale (INSERM), U964/Centre National de Recherche Scientifique (CNRS), UMR 1704/Université de Strasbourg, Illkirch, and Centre Hospitalier Universitaire, Strasbourg, France.
    Basic genetics and cytogenetics : a brief reminder / Karen Sermon -- How to analyse a single blastomere? Application of whole-genome technologies : micro-arrays and next generation sequencing / Parveen Kumar, Masoud Zamani Esteki, Niels Van der Aa, and Thierry Voet -- Meiosis : how to get a good start in life / Ursula Eichenlaub-Ritter -- Chromosomes in early human embryo development : incidence of chromosomal abnormalities, underlying mechanisms and consequences for development / E.B. Baart and D. Van Opstal -- DNA is not the whole story : transgenerational epigenesis and imprinting / Ashwini Balakrishnan and J. Richard Chaillet -- Genes are not the whole story : retrotransposons as new determinants of male fertility / Patricia Fauque and Deborah Bourc'his -- Chromosomal causes of infertility : the story continues / Svetlana A. Yatsenko and Aleksandar Rajkovic -- Genes and infertility / Inge Liebaers, Elias Ellnati, Willy Lissens, and Stéphane Viville -- Genetic counselling & gamete donation in assisted reproductive treatment / Alison Lashwood and Alison Bagshawe -- Genetic testing for infertile patients / Willem Verpoest -- Preimplantation genetic diagnosis / Jan Traeger-Synodinos and Catherine Staessen -- Epigenetics and art / Esther Baart, Diane Van Opstal and Aafke van Montfoort -- Ethical considerations in human reproductive genetics / Guido de Wert and Wybo Dondorp.
  • 2013 Wiley
    edited by Robert G. Webster, Arnold S. Monto, Thomas J. Braciale, Robert A. Lamb.
    Influenza: perspective -- Human influenza: one health, one world -- Influenza pandemics: history and lessons learned -- Structure and replication -- Structure, disassembly, assembly, and budding of influenza viruses -- The virus genome and its replication -- Influenza glycoproteins: hemagglutinin and neuraminidase -- Proton channels of influenza A and B viruses -- The NS1 protein: a master regulator of host and viral functions -- Structure and function of the influenza virus replication machinery and PB1-F2 -- The genome and its manipulation: recovery of the 1918 virus and vaccine virus generation -- Pathogenesis -- Evolution and ecology of influenza viruses -- Ecology and evolution of influenza viruses in wild and domestic birds -- Influenza in swine -- Equine/canine/feline/seal influenza -- Emergence and evolution of the 1918, 1957, 1968, and 2009 pandemic virus strains -- Epidemiology and surveillance -- Influenza surveillance and laboratory diagnosis -- Epidemiology of influenza -- Immunology of influenza -- Innate immunity -- Antibody-mediated immunity -- Cell-mediated immunity -- Vaccines and vaccine development -- Immunogenicity, efficacy of inactivated/live virus seasonal and pandemic vaccines -- New approaches to vaccination -- Control of influenza in animals -- Influenza vaccine production -- Clinical aspects and antivirals -- Human influenza: pathogenesis, clinical features, and management -- Antivirals: targets and use -- The control of influenza and cost-effectiveness of interventions -- Applications of quantitative modeling to influenza virus transmission dynamics, antigenic and genetic evolution, and molecular structure -- Pandemic preparedness and response -- Influenza: the future -- The outbreak of H7N9.
  • 2007
    James H. Lake.
    Status: Not Checked OutLane Catalog Record
    Evolution of integrative medicine and implications for mental health care -- Philosophical problems -- Paradigms in medicine, psychiatry, and integrative medicine -- Foundations of clinical methodology in integrative medicine -- History taking, assessment, formulation in integrative mental health care -- Starting and maintaining integrative treatment in mental health care -- Symptom-focused integrative mental health care -- Integrative management of depressed mood -- Integrative management of mania and cyclic mood changes -- Integrative management of anxiety -- Integrative management of psychosis -- Integrative management of dementia and mild cognitive impairment -- Integrative management of substance abuse and dependence -- Integrative management of disturbances of sleep and wakefulness.
  • 2011 ClinicalKey
    [edited by] Joanne Wolfe, Pamela S. Hinds, Barbara M. Sourkes.
    "The Textbook of Interdisciplinary Pediatric Palliative Care, by Drs. Joanne Wolfe, Pamela Hinds, and Barbara Sourkes, aims to inform interdisciplinary teams about palliative care of children with life-threatening illness. It addresses critical domains such as language and communication, symptoms and quality of life, and the spectrum of life-threatening illnesses in great depth. This comprehensive product takes a first-of-its-kind team approach to the unique needs of critically ill children. It shows how a collaborative, interdisciplinary care strategy benefits patients and their families. If you deal with the complex care of critically ill children, this reference provides a uniquely integrated perspective on complete and effective care."--Publisher's website.
  • 2009
    Anne-Emanuelle Birn, Yogan Pillay, Timothy H. Holtz.
    Status: Not Checked OutLane Catalog Record
    The historical origins of modern international health -- International health agencies, activities, and other actors -- The political economy of health and development -- What do we know, what do we need to know, and why it matters : data on health -- Epidemiologic profiles of global health and disease -- Societal determinants of health and social inequalities in health -- Health under crisis -- Globalization, trade, work, and health -- Health and the environment -- Health economics and the economics of health -- Understanding and organizing health care systems -- Toward healthy societies : from ideas to action -- Doing international health.
  • 2016 ClinicalKey
    Eric J. Topol, Paul S. Teirstein.
    Ideal for cardiologists, surgeons, and referring physicians who need a clinical guide to interventional procedures, Textbook of Interventional Cardiology focuses on the latest treatment protocols for managing heart disorders at every level of complexity. In this updated edition, Dr. Topol continues to bring together experts in the field who present the current state of knowledge and clinical practice in interventional cardiology, including cutting-edge theories, trends, and applications of diagnostic and interventional cardiology, as well as peripheral vascular techniques and practices.
  • 2008
    [edited by] Eric J. Topol.
    Status: Not Checked OutLane Catalog Record
  • 2006
    edited by Inderbir S. Gill.
    Status: Not Checked OutLane Catalog Record
  • 2006
    Arthur C. Guyton, John E. Hall.
    Status: Not Checked OutLane Catalog Record
  • 2014 CRCnetBASE
    edited by Babak Kateb, John D. Heiss.
    Ch. 1. From nanotechnology to nanoneuroscience/nanoneurosurgery and nanobioelectronics : a historical review of milestones / Vicky Yamamoto ... [et al.] -- ch. 2. Nanoneurology and nanoneurosurgery / Geoffrey S. F. Ling, Robbin Miranda, and Gill Pratt -- ch. 3. Nanopolymers and nanoconjugates for central nervous system diagnostics and therapies / Giancarlo Suffredini and Lucien M. Levy -- ch. 4. Micelles and liposomes : lipid nanovehicles for intracerebral drug delivery / Massimo S. Fiandaca and Krystof S. Bankiewicz -- ch. 5. Peptide and protein-based nanoparticles / Ayaz M. Khawaja and John D. Heiss -- ch. 6. Endohedral metallofullerenes, iron oxide agents, and gold nanoparticles for brain imaging / Martina A. McAteer and Robin P. Choudhury -- ch. 7. Carbon nanoplatforms and their application for neurological disorders / Houman Badrzadeh, Peyman Tashkandi, Michelle Knosp, and Babak Kateb -- ch. 8. Dendrimers / Ayaz M. Khawaja and John D. Heiss Chapter -- ch. 9. Ligand-based targeting of therapeutic and imaging agents for cancer / Qimeng Quan, Seulki Lee, and Xiaoyuan Chen -- ch. 10. Immune-based targeting in cancer / Dwain K. Irvin, Chirag G. Patil, and Keith L. Black -- ch. 11. Directed drug convection using magnetic nanoparticles as therapeutic carriers : meeting the challenge of specific brain pharmacotherapeutics, non-ligand-based central nervous system targeting, including magnetic focusing / David F. Moore ... [et al.] -- ch. 12. Intralesional and intraparenchymal convection-enhanced delivery of nanoparticles / Tatsuhiro Fujii ... [et al.] -- ch. 13. Transport of nanoparticles across blood-brain barrier / Robert T. Wicks, Zev A. Binder, and Alessandro Olivi -- ch. 14. Nanomedicine treatment strategies that exploit unique characteristics of tumor vasculature and microenvironment / Jun Wu, Tatsuhiro Fujii, and Mike Y. Chen -- ch. 15. Focused ultrasound for noninvasive neuromodulation / Martin O. Culjat ... [et al.] -- ch. 16. Nanosensors / J. Matthew Dubach and Heather A. Clark -- ch. 17. Implantable infusion pumps incorporating nanotechnology / Ellis Meng, Tuan Hoang, and Uttam Sinha -- ch. 18. Nanostructured surfaces for intracerebral neurotransmitter recording / David A. Price ... [et al.] -- ch. 19. Therapy for neuronopathic lysosomal storage diseases / Ayaz M. Khawaja, John D. Heiss, and Roscoe O. Brady -- ch. 20. Nanotechnology for cerebral aneurysm treatment / Jean Paul Allain, Teodoro Tigno, and Rocco Armonda -- ch. 21. Improving treatment of stroke through nanotechnology / Francesca Nicholls ... [et al.] -- ch. 22. Molecular medical devices for nanoneurosurgery / Rutledge Ellis-Behnke -- ch. 23. Applications of nanotechnology in epilepsy / Paul R. Carney -- ch. 24. Applications of nanotechnology to diseases of the spine / Bryn S. Moore and Steven A. Toms -- ch. 25. Nanoparticle-based treatment and imaging of brain tumors : potentials and limitations / Bong-Seop Lee ... [et al.] -- ch. 26. Tumor-targeted nanodrugs for treatment of primary brain tumors / Joseph T. Cheatle and Michele R. Aizenberg -- ch. 27. Application of nanotechnology in the diagnosis and treatment of brain metastasis / Joel C. Sunshine ... [et al.] -- ch. 28. Nanotechnology in extra-axial and pituitary tumors / Aimee Two, J. Peter Gruen, and Gabriel Zada -- ch. 29. Using nanoparticles in diagnosis and treatment of CNS infection / Zion Zibly, Cody D. Schlaff, and John D. Heiss -- ch. 30. Applications of nanotechnology in movement disorders / Patrick Pezeshkian ... [et al.] -- ch. 31. Nanomedicine in demyelinating disease : application to diagnosis and therapy in multiple sclerosis / Emily C. Leibovitch and Steven Jacobson -- ch. 32. Applications of nanotechnology in degenerative disorders of the brain / Ayaz M. Khawaja and John D. Heiss -- ch. 33. Brain-machine interface and rehabilitation / Martin Pham, Alexander Taghva, and Ali R. Rezai -- ch. 34. Nanobioelectronics for noninvasive neuronal therapy / Evangelia Hondroulis, Jairo Nelson, and Chen-Zhong Li -- ch. 35. In vitro and in vivo techniques to assess neurotoxicity of nanoparticles / Thomas Birngruber ... [et al.] -- ch. 36. Nanorobotics for neurosurgery / Robbin Miranda, Gill Pratt, and Geoffrey S. F. Ling -- ch. 37. Imaging and tracking therapeutic cells with nanoparticles / Gang Niu and Joseph A. Frank -- ch. 38. Micro- and nanotechnology in nerve repair / Ali C. Ravanpay and Michel Kliot -- ch. 39. Nanotechnology : applications to pediatric neurosurgery / Giancarlo Suffredini and Robert F. Keating -- ch. 40. Food and drug administration regulatory framework for nanodrugs and nanodevices and the combination / Vicky Yamamoto -- ch. 41. Nanoneuroscience and nanoneurosurgery : a key component of President Obama's brain mapping initiative / Babak Kateb ... [et al.].
  • 2013 ClinicalKey
    edited by Joseph E. Pizzorno, Michael T. Murray.
    Covering preventive, non-invasive, and natural treatments, this 4th Edition offers more than just alternative medicine. It promotes an integrated practice that can utilize natural medicine, traditional Western medicine, or a combination of both in a comprehensive, scientific treatment plan. Based on a combination of philosophy and clinical studies, this book helps you provide health care that identifies and controls the underlying causes of disease, is supportive of the body's own healing processes, and is considerate of each patient's unique biochemistry. Internationally known authors Joseph Pizzorno and Michael Murray include detailed pharmacologic information on herbs and supplements, plus evidence-based coverage of diseases and conditions to help you make accurate diagnoses and provide effective therapy. 13 useful appendices offer quick lookup of frequently used charts, handouts, and information. New chapters are included on hot topics such as female infertility, medicinal mushrooms, natural products and quality control, pregnancy health and primary prevention, and Vitamin K; new appendices include a supplier certification questionnaire and cervical escharotics treatment. Thorough updates ensure that you use only the most current research and provide the most effective treatment of patients. Tabs in Specific Health Problems section separate more than 70 alphabetized diseases/conditions. One convenient volume replaces the cumbersome two-volume set for easy, convenient reference.
  • 2009 ScienceDirect
    2009 ClinicalKey
    edited by Ajay K. Singh, Gordon H. Williams.
    Part I: The kidney as an endocrine organ -- Section I: Erythropoietin -- Erythropoietin: an historical overview of physiology, molecular biology and gene regulation / David R. Mole, Peter J. Ratcliffe -- Erythropoiesis: the roles of erythropoietin and iron / Herbert Y. Lin -- Extra-hematopoietic action of erythropoietin / Zheqing Cal, Gregg L. Semenza -- Development of recombinant erythropoietin and erythropoietin analogs / Iain C. Macdougall -- Erythropoietin, anemia and kidney disease / Ajay K. Singh ... [et al.] -- Section II: Vitamin D, PTH and novel regulators of phosphate -- Vitamin D and the kidney: introduction and historical perspective / Tejas Patel, Ajay K. Singh --- Vitamin D: molecular biology and gene regulation / Adriana S. Dusso, Alex J. Brown -- Endocrine regulation of phosphate homeostasis / Harald Jüppner, Anthony A. Portale -- Section III: Renin-Angiotensin -- The history of the renin-angiotensin system / Joel Menard -- Molecular biology of renin and regulation of its gene / Timothy L. Reudelhuber, Daniel F. Catanzaro -- Physiology and regulation of the renin-angiotensin-aldosterone system / Robert M. Carey, Shetal H. Padia -- The renin-angiotensin-aldosterone system and the kidney / Benjamin Ko, George Bakris -- The renin-angiotensin system and the heart / Aaron J. Trask, Carlos M. Ferrario -- Renin-angiotensin blockage: therapeutic agents / Domenic A. Sica -- Part II: The kidney as a hormonal target -- Section IV: Antidiuretic hormone -- Vasopressin in the kidney: historical aspects / Lynn E. Schlanger, Jeff M. Sands -- Molecular biology and gene regulation of vasopressin / Swasti Tiwari, Carolyn A. Ecelbarger -- Vasopressin antagonists in physiology and disease / Tomas Berl, Robert W. Schrier -- Diabetes insipidus and SIADH / Michael L. Moritz, Juan Carlos Ayus -- Section V: The atrial peptides -- ANP, BNP and CNP: physiology and pharmacology of the cardiorenal axis / Candace Y. W. Lee, John C. Burnett Jr -- Section VI: Aldosterone -- Aldosterone: history and introduction / John Coghlan, James F. Tait -- Aldosterone receptors and their renal effects: molecular biology and gene regulation / Celso E. Gomez-Sanchez, Elise P. Gomes-Sanchez, Mario Galigniana -- Aldosterone and its cardiovascular effects / Rajesh Garg, Gail K. Adler -- Regulation of aldosterone production / William E. Rainey, Windy B. Bollag, Carlos M. Isales -- Section VII: Endocrine disorders in renal failure -- Insulin resistance and diabetes in chronic renal disease / Donald C. Simonson -- Growth hormone / John D. Mahan -- Sexual dysfunction in men and women with chronic kidney disease / Biff F. Palmer -- Thyroid status in chronic renal failure patients: a non-thyroidal illness syndrome / Victoria S. Lim, Manish Suneja -- Metabolic acidosis of chronic kidney disease / Jeffrey A. Kraut, Glenn T. Nagami -- Pregnancy and the kidney / Chun Lam, S. Ananth Karumanchi.
  • 2014 Cambridge
    edited by Michael Selzer, Stephanie Clarke, Leonardo Cohen, Gert Kwakkel, Robert Miller.
  • 2014 Cambridge
    edited by Michael Selzer, Stephanie Clarke, Leonardo Cohen, Gert Kwakkel, Robert Miller.
  • 2013 Springer
    A. Joseph Layon, Andrea Gabrielli, William A. Friedman, editors.
    Listening to an injured brain is not easy. It takes knowledge, dedication, and understanding of the critically ill patient and their family. It takes an appreciation of the logistics of care in these difficult times of imbalance between more and sicker patients and fewer medical specialists. The impact of the right personnel, whose interest and training is in neurocritical care, has shown promise, both in terms of improving patient outcome and quality. The editors have updated this second edition with the latest knowledge and trends. Gathering together a group of international experts who champions the three characteristics Patient and Family Centered High Quality Care, Education, and Discovery needed in our NeuroICUs, the editors present to the reader a comprehensive textbook of neurocritical care, incorporating best practice / evidence-based medicine and performance improvement. This book is not an effort to embellish the shelf of a medical library; it is a practical bedside friend to be used to improve the neurological outcomes of those for whom we are honored to care: our patients.
  • 2015 Springer
    edited by Helena Knotkova, Dirk Rasche.
    Textbook of Neuromodulation encompasses the basic principles, methods and current clinical applications of invasive and non-invasive neuromodulation. Neurophysiological systems are reviewed along with the basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. The overview of the neuromodulatory techniques is provided with special regard to safety and specific patient populations. Comprehensive and authored by leaders in the field, this resource presents the clinical potential, significance and practical applications of this innovative treatment approach.
  • 2013 ClinicalKey
    edited by Raashid Luqmani [and others].
    Clinical History and Examination -- Physiology and pathology of the musculoskeletal system -- Epidemiology and genetics of rheumatic diseases -- Investigations -- Medical management of arthritis -- Musculoskeletal infection -- Role of the allied health professional -- Surgical management of joint disorders -- Fracture management -- Management of multiple trauma -- Children's fractures -- Regional injuries -- Sport and exercise associated problems in adults -- Generalized musculoskeletal problems -- Osteoarthritis and crystal arthropathies -- Inflammatory arthritis -- Systemic diseases -- Systemic complications of rheumatic diseases and rare arthropathies -- Bone disorders -- Tumours of the musculoskeletal system and pathological fractures -- Upper limb -- Cervical and lumbar spine -- Lower limb -- Normal variants in children -- Upper and lower limb disorders in children -- The paediatric spine and neuromuscular conditions -- Arthritis in children -- Sport and exercise associated problems in children and adolescents.
  • 2006 MyiLibrary
    edited by Betty R. Ferrell, Nessa Coyle.
    General principles -- Symptom assessment and management -- Psychosocial support -- Spiritual care -- Special patient populations -- End-of-life care across settings -- Pediatric palliative care -- Special issues for the nurse in end-of-life care -- Models of excellence and innovative community projects -- "A good death."
  • v. 1-2, 2006.
    edited by John Harper, Arnold Oranje, Neil Prose.
    Status: Not Checked OutLane Catalog Record
  • 2010 Ovid
    editors, Gary R. Fleisher, Stephen Ludwig ; associate editors, Richard G. Bachur ... [et al.].
    Resuscitation-pediatric basic and advanced life support -- Neonatal resuscitation -- Shock -- Sedation and analgesia -- Emergency airway management-rapid sequence intubation -- Emergency medical services and transport medicine -- Emergency department recognition and management of victims of biological and chemical terrorism -- Abdominal distension -- Apnea -- Ataxia -- Breast lesion -- Coma and altered level of consciousness -- Constipation -- Cough -- Cyanosis -- Crying and colic in early infancy -- Dehydration -- Diarrhea -- Disturbed child -- Dizziness -- Edema -- Epistaxis -- Eye-red -- Eye-strabismus -- Eye-unequal pupils -- Eye-visual disturbances -- Fever -- Foreign body-ingestion/aspiration -- Gastrointestinal bleeding -- Groin masses -- Hearing loss --- Patients with heart murmurs -- Hematuria -- Hypertension -- Immobile arm -- Injury-ankle -- Injury-head -- Injury-knee -- Injury-shoulder -- Jaundice-unconjugated hyperbilirubinemia -- Jaundice-conjugated hyperbilirubinemia -- Limp -- Lymphadenopathy -- Neck mass -- Neck stiffness -- Odor-unusual -- Oligomenorrhea -- Oral lesions -- Pain-abdomen -- Pain-back -- Pain-chest -- Pain-dysphagia -- Pain-dysuria -- Pain-earache -- Headache -- Pain-joints -- Pain-scrotal -- Pallor -- Palpitations -- Polydipsia -- Rash-eczematous -- Rash-maculopapular -- Rash-papular lesions -- Rash-papulosquamous lesions -- Rash-petechiae and purpura -- Rash-urticaria -- Rash-vesicobullous -- Respiratory distress -- Seizures -- The septic-appearing infant -- Sore throat -- Stridor -- Syncope -- Tachycardia -- Urinary frequency in childhood -- Vaginal bleeding -- Vaginal discharge -- Vomiting -- Weakness -- Wheezing -- Weight loss -- Asthma and allergic emergencies -- Bite and stings -- Cardiac emergencies -- Dermatologic urgencies and emergencies -- Endocrine emergencies -- Environmental emergencies -- Injuries involving radiation -- Gastrointestinal emergencies -- Pediatric and adolescent gynecology -- Hematologic emergencies -- Infectious disease emergencies -- Infectious disease emergencies-sexually transmitted diseases -- Metabolic emergencies -- Problems in the early neonatal period -- Neurologic emergencies -- Oncologic emergencies -- Pulmonary emergencies -- Emergencies in cystic fibrosis -- Renal and electrolyte emergencies -- Rheumatologic emergencies -- Toxicologic emergencies -- Evaluation of the ill returning traveler -- An approach to the injured child -- Major trauma -- Minor trauma-lacerations -- Abdominal trauma -- Burns -- Dental trauma -- Otolaryngologic trauma -- Facial trauma -- Genitourinary trauma -- Hand trauma -- Musculoskeletal trauma -- Neck trauma -- Neurotrauma -- Eye trauma -- Thoracic trauma -- Minor lesions and injuries -- Approach to the care of the technology-assisted child -- Abdominal emergencies -- Dental emergencies -- Otolaryngologic emergencies -- Urologic emergencies -- Orthopedic emergencies -- Neurosurgical emergencies, nontraumatic -- Ophthalmic emergencies -- Thoracic emergencies -- Transplantation emergencies -- Adolescent emergencies -- Behavioral emergencies -- Child abuse -- Psychiatric emergencies -- Ultrasound -- Illustrated techniques of pediatric emergency procedures -- App. A: Pediatric emergency medicine equipment -- App. B: Emergency drug compendium -- App. C: Practical information -- App. D: Parental instruction sheets -- App. E: Clinical pathways in emergency medicine.
    Also available: Print – 2010
  • 2006
    editors, Gary R. Fleisher, Stephen Ludwig, Fred M. Henretig ; associate editors, Richard M. Ruddy, Benjamin K. Silverman.
    Status: Not Checked OutLane Catalog Record
  • 2008
    editors, Christopher King, Fred M. Henretig ; associate editors, Brent R. King ... [et al.] ; illustrator, Christine D. Young.
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Stefano Guandalini, Anil Dhawan, David Branski [d.], editors.
    Microvillus Inclusion Disease and Tufting Enteropathy -- The Spectrum of Autoimmune Enteropathy -- Congenital Problems of the Gastrointestinal Tract -- Pyloric Stenosis -- Gastrointestinal Problems of the Newborn -- Enteral Nutrition in Preterm Neonates -- Parenteral Nutrition in Premature Infants -- Infectious Esophagitis -- Eosinophilic Esophagitis -- Gastroesophageal Reflux -- Esophageal Achalasia -- Helicobacter Pylori Gastritis and Peptic Ulcer Disease -- Menetrier Disease -- Viral Diarrhea -- Bacterial Infections -- Intestinal Parasites -- Persistent Diarrhea in Children in Developing Countries -- HIV and the Intestine -- Functional Abdominal Pain and Other Functional Gastrointestinal Disorders -- Disorders of Sucking and Swallowing -- Defecation Disorders in Children: Constipation and Functional Fecal Incontinence -- Hirschsprungs Disease and Intestinal Neuronal Dysplasias -- Chronic Intestinal Pseudo-Obstruction in Childhood -- Gastrointestinal and Nutritional Problems in Neurologically Handicapped Children -- Cyclic Vomiting Syndrome -- Food Allergy -- Eosinophilic Gastroenteropathy -- Crohns Disease -- Indeterminate Colitis/Inflammatory Bowel Disease Unclassified (IBD-U) -- Ulcerative Colitis -- Vasculitides Including Henoch Schnlein Purpura -- Lymphonodular Hyperplasia -- Acute Pancreatitis -- Hereditary Pancreatitis and Chronic Pancreatitis in Children -- Fecal Microbial Transplant: For Whom, How, and When -- Congenital Disorders of Intestinal Electrolyte Transport -- Immunodeficiency Disorders Resulting in Malabsorption -- Congenital Disorders of Lipid Transport -- Pancreatic Insufficiency -- Celiac Disease -- Cystic Fibrosis -- Small Intestinal Bacterial Overgrowth -- Short Bowel Syndrome -- MalnutritionA Global Problem -- Probiotics -- Enteral Nutrition -- Parenteral Nutrition in Infants and Children -- Pediatric Intussusception -- Meckels Diverticulum -- Acute Appendicitis -- Gastrointestinal Vascular Anomalies -- Polyps and Other Tumors of the Gastrointestinal Tract -- Normal Liver Anatomy and Introduction to Liver Histology -- Diagnostic Procedures in Pediatric Hepatology -- Infantile Cholestasis: Approach and Diagnostic Algorithm -- Biliary Atresia and Choledochal Malformations -- Congenital Hepatic Fibrosis, Carolis Disease and Other Fibrocystic Liver Diseases -- Familial Intrahepatic Cholestasis -- Alagille Syndrome -- Chronic Viral Hepatitis B and C -- Bacterial, Fungal and Parasitic Infections of the Liver -- Liver Disease in Primary Immunodeficiencies -- Autoimmune Liver Disease -- Inherited Metabolic Disorders and the Liver -- Wilsons Disease -- Nonalcoholic Fatty Liver Disease -- Vascular Disorders of the Liver -- Portal Hypertension in Children -- Liver Tumors in Children -- Acute Liver Failure in Children -- Complications of Cirrhosis in Children -- Nutritional Management of Children with Liver Disease -- Pediatric Liver Transplantation -- Growing up with Liver Disease -- New Horizons in Pediatric Hepatology: A Glimpse of the Future.
  • 2011 ScienceDirect
    [edited by] James T. Cassidy , Ross E. Petty, Ronald M. Laxer, Carol B. Lindsley.
    Section 1. Basic concepts -- section 2. Chronic arthritis -- section 3. Systemic connective tissue diseases -- section 4. Systemic vasculitis -- section 5. Arthritis related to infection -- section 6. Systemic disorders with rheumatic manifestations -- section 7. Noninflammatory causes of musculoskeletal pain.
  • 2016 ClinicalKey
    [edited by] Ross E. Petty, Ronald M. Laxer, Carol B. Lindsley, Lucy Wedderburn.
  • 2012 Springer
    Asif Muneer, Manit Arya, Simon Horenblas, editors.
  • 2009 Springer
    Kewal K. Jain.
    Basics of Personalized Medicine -- Molecular Diagnostics as Basis of Personalized Medicine -- Role of Biomarkers in Personalized Medicine -- Pharmacogenetics -- Pharmacogenomics -- Role of Pharmacoproteomics -- Role of Metabolomics in Personalized Medicine -- Personalized Biological Therapies -- Development of Personalized Medicine -- Personalized Therapy for Cancer -- Personalized Management of Neurological Disorders -- Personalized Therapy of Cardiovascular Diseases -- Personalized Management of Miscellaneous Disorders -- Personalized Preventive Medicine -- Organization of Personalized Medicine -- Ethical and Regulatory Aspects of Personalized Medicine -- Economics of Personalized Medicine -- Future of Personalized Medicine.
  • 2014 ClinicalKey
    Mark H. Swartz, MD, FACP.
    "Derive the maximum diagnostic information from interviewing and examining patients with Textbook of physical diagnosis. Employing a compassionate, humanistic approach, Dr. Swartz explores how cultural differences can influence communication, diet, family relationships, and health practices and beliefs, and demonstrates that your interpersonal awareness is just as essential in physical diagnosis as your level of technical skill. This medical reference book features numerous high-quality color images, an easy-to-use design, and detailed descriptions of exam techniques, making it an essential guide for physicians, nurse practitioners, and physician assistants"-- Publisher's description.
  • Google Books
    Howell, William H.
    Also available: Print – 1917.
  • 2009 PsychiatryOnline
    edited by Alan F. Schatzberg and Charles B. Nemeroff.
  • 2009 PsychiatryOnline
    edited by Glen O. Gabbard ; contributors, Jon G. Allen ... [et al.].
    Theoretical models of psychodynamic psychotherapy -- Techniques of psychodynamic psychotherapy -- Techniques of brief psychodynamic psychotherapy -- Applications of psychodynamic psychotherapy to specific disorders : efficacy and indications -- Combining psychodynamic psychotherapy with medication -- Theory of cognitive therapy -- Techniques of cognitive-behavioral therapy -- Applications of individual cognitive-behavioral therapy to specific disorders : efficacy and indications -- Combining cognitive-behavioral therapy with medication -- Theory of interpersonal psychotherapy -- Techniques of individual interpersonal psychotherapy -- Applications of individual interpersonal psychotherapy to specific disorders : efficacy and indications -- Combining interpersonal psychotherapy with medication -- Theory of supportive psychotherapy -- Techniques of individual supportive psychotherapy -- Applications of individual supportive psychotherapy to psychiatric disorders : efficacy and indications -- Combining supportive psychotherapy with medication -- Family systems theory and practice -- Couples therapy -- Emotionally focused couples therapy : an attachment-based treatment -- Psychodynamic couples therapy : an object relations approach -- Behavioral couples therapy -- Psychodynamic group therapy -- Family intervention for psychotic and severe mood disorders -- Group cognitive-behavioral therapy for chronic pain -- Theory and practice of psychotherapy integration -- Theory and practice of dialectical behavioral therapy -- Theory and practice of mentalization-based therapy -- Brain processes informing psychotherapy -- Professional boundaries in psychotherapy.
  • 2011 Springer
    Jason X.-J. Yuan, Joe G.N. Garcia, Charles A. Hales, Stuart Rich, Stephen L. Archer, John B. West.
  • 2011 Springer
    Michael A. DeVita, Ken Hillman, Rinaldo Bellomo, editors.
    Rapid response systems history and terminology -- RR's general principles -- Measuring and improving safety -- Integrating a rapid response system into a patient safety program -- Acute hospitalist medicine and the rapid response system -- Medical trainees and patient safety -- Rapid response systems: a review of the evidence -- Healthcare systems and their (lack of) integration -- Creating process and policy change in healthcare -- The challenge of predicting in-hospital cardiac arrests and deaths -- The meaning of vital signs -- Matching illness severity with level of care -- Causes of failure to rescue -- Impact of hospital size and location on feasibility of RRS -- Barriers to the implementation of RRS -- An overview of the afferent limb -- The impact of delayed RRS activation -- The case for family activation of the RRS -- RRT: nurse-led RRSs -- MET: physician-led RRSs -- Pediatric RRSs -- Sepsis response team -- Other efferent limb teams: (BAT, DAT, M, H, and trauma) -- Other efferent limb teams: crisis response for obstetric patients -- Personnel resources for responding teams -- Equipment, medications, and supplies for an RRS -- The administrative limb -- The second victim -- RRSs in teaching hospitals -- The nurse's view of RRS -- Resident training and RRSs -- Optimizing RRSs through simulation -- Evaluating effectiveness of complex system interventions -- RRS education for ward staff -- Standardized process and outcome assessment tool -- The impact of RRSs on choosing "not-for-resuscitation" status -- The costs and savings.
  • 2011 Springer
    Luigi P. Badano, Roberto M. Lang, José Luis Zamorano (Editors).
    The evolution of three-dimensional echocardiography: how did it happen -- Technical principles of transthoracic three-dimensional echocardiography -- 3D transesophageal echocardiographic technologies -- Three-dimensional echocardiography in clinical practice -- Advanced evaluation of LV functions with 3D echocardiography -- Three-dimensional echocardiographic evaluation of the mitral valve -- Three-dimensional echocardiographic evaluation of LV dyssynchrony and stress testing -- Three-dimensional echocardiography of aortic valve -- Three-dimensional echocardiographic evaluation of the right ventricle -- Three-dimensional echocardiography in congenital heart disease -- Three-dimensional echocardiography to assess intra-cardiac masses -- Real time three dimensional transesophageal echocardiography for guidance of catheter based interventions -- Future developments of three-dimensional echocardiography -- Real time three-dimensional transesophageal echocardiography -- The role of echocardiography in the surgical management of degenerative mitral valve disease -- Visualization and assessment of coronary arteries with three-dimensional echocardiography -- Assessment of tricuspid valve morphology and function -- Role of three-dimensional echocardiography in drug trials.
  • 2013 Springer
    Ronald R. Krueger, Jonathan H. Talamo, Richard L. Lindstrom, editors.
    Evolution of Cataract Surgery -- Current Outcomes with Cataract Surgery: Can We Do Better? -- Femtosecond Laser Fundamentals -- Challenges of Femtosecond Laser Technologies for Cataract Surgery -- Imaging Systems and Image-Guided Surgery -- The Patient Interface: Setting the Stage for Treatment -- Laser Capsulotomy -- Nucleus Fragmentation and Disassembly in ReLACS -- Primary Transcorneal Laser Incisions -- Relaxing Incisions for Astigmatism Correction in ReLACS -- Femtosecond Laser Versus Phacoemulsification -- Economics of ReLACS: Marketing a New Technology to Your Patients -- Step-By-Step: Starting Your ReLACS Practice -- Global Implications of Refractive Laser Assisted Cataract Surgery (ReLACS) -- Commercially Available Systems: Alcon/LenSx -- Commercially Available Systems: LensAR Laser System -- Commercially Available Systems: OptiMedica's Catalys Precision Laser System -- Commercially Available Systems: The TECHNOLAS Femto-Cataract Approach -- The Future of ReLACS and Femtosecond Laser Ocular Surgery.
  • 2009 Springer
    Andres M. Lozano, Philip L. Gildenberg, Ronald R. Tasker (eds.).
  • 2014 Cambridge
    edited by Michael Brainin, MD, PhD, Professor and Chair, Department of Clinical Neuroscience and Preventive Medicine, Danube University Krems, Krems, Austria, Wolf-Dieter Heiss, MD, PhD, Professor of Neurology, Emeritus Director, Max Planck Institute for Neurological Research and Department of Neurology, University of Cologne, Cologne, Germany ; editorial assistant, Susanne Tabernig, MD, Vienna, Austria.
    Neuropathology and pathophysiology of stroke / Konstantin A. Hossmann and Wolf-Dieter Heiss -- Common causes of ischemic stroke / Bo Norrving -- Neuroradiology / Jochen B. Fiebach, Patrik Michel, and Jens Fiehler -- Imaging for prediction of functional outcome and for assessment of recovery / Wolf-Dieter Heiss -- Ultrasound in acute ischemic stroke -- Basic epidemiology of stroke and risk assessment / Jaako Tuomilehto -- Common risk factors and prevention / Michael Brainin, Yvonne Teuschl, and Karl Matz -- Cardiac diseases relevant to stroke / Claudia St llberger and Josef Finsterer -- Common stroke syndromes / line Odier and Patrik Michel -- Less common stroke syndromes / Wilfried Lang -- Intracerebral hemorrhage / Corina Epple, Michael Brainin, and Thorsten Steiner -- Subarachnoid hemorrhage / Philip Lichti and Thorsten Steiner -- Cerebral venous thrombosis / Jobst Rudolf -- Behavioral neurology of stroke / Jose M. Ferro, Isabel P. Martins, and Lara Caeiro -- Stroke and dementia / Barbara Casolla and Didier Leys -- Ischemic stroke in the young and in children / Valeria Caso and Didier Leys -- Stroke units and clinical assessment / Danilo Toni and ngel Chamorro -- Acute therapies for stroke / Richard E. O'Brien and Kennedy R. Lees -- Interventional intravascular therapies for stroke / Pasquale Mordasini, Jan Gralla, and Gerhard Schroth -- Management of acute ischemic stroke and its late complications / Natan M. Bornstein and Eitan Auriel -- Infections in stroke / Achim Kaasch and Harald Seifert -- Secondary prevention / Hans-Christoph Diener, Sharan K. Mann, and Gregory W. Albers -- Neurorehabilitation practice for stroke patients / Sylvan J. Albert and Jorg Kesselring.
  • 2006
    edited by Joe J. Tjandra, Gordon J.A. Clunie, Andrew H. Kaye, Julian A. Smith.
    Status: Not Checked OutLane Catalog Record
    Peritonitis and intra-abdominal abscess / J.J. Tjandra -- Ascites / D.M.A. Francis & D.A.K. Watters -- Neck swellings / C.J. O'Brien -- Dysphagia / R.J.S. Thomas -- Leg ulcers / J. Harris -- Leg swelling / S.T.F. Chan & D.M.A. Francis -- Haematuria / D. Lenz -- Post-operative complications / P. Devitt -- Claw hand / W. Morrison -- Massive haemoptysis / J.A. Smith -- Epistaxis / N. Vallance -- Leg pain / B. Kavar -- Acute scrotal pain / A.J. Costello -- Acute back pain / J.V. Rosenfeld -- Post-traumatic confusion / J.D. Laidlaw -- Double vision / J.E.K. Galbraith. Pre-operative management / I.G. Martin -- Anaesthesia and pain management / D. Williams -- Post-operative management / P. Devitt -- Surgical techniques / D.M.A. Francis -- Nutrition and the surgical patient / B.K. Parry & A.G. Hill -- Care of the critically ill patient / J.J. Presneill & J.F. Cade -- Surgical infections / J.C. Hall -- Transplantation surgery / D.M.A. Francis -- Principles of surgical oncology / R.J.S. Thomas -- Gastro-oesophageal reflux / G.G. Jamieson -- Tumours of the oesophagus / S. Law & J. Wong -- Peptic ulcer disease / S.C.S. Chung -- Gastric neoplasms / I.G. Martin -- Gallstones / D. Fletcher -- Benign and malignant diseases of the hepatobiliary system / N. Collier & D. Morris -- Liver infections / C. Christophi & V. Muralidharan -- Diseases of the Pancreas / J. Toouli -- Portal hypertension / C. Christophi & V. Muralidharan -- Small bowel obstruction / J.J. Tjandra -- Large bowel obstruction / A.L. Polglase -- Mesenteric vascular disease / J.J. Tjandra -- Principles of plastic surgery / W. Morrison -- Principles of trauma management / S.K. D'Amours & S.A. Deane -- Burns / R.T. Judson -- Fractures and dislocations / P. Choong -- Diseases of bone and joints / P. Choong -- Head injuries / A.H. Kaye -- Intracranial tumours, infection and aneurysms / A.H. Kaye -- Nerve injuries, peripheral nerve entrapments and spinal cord compression / A.H. Kaye -- Disorders of the arterial system / J. Harris -- Extracranial vascular disease / J. Harris -- Venous and lymphatic diseases of the limbs / M. Grigg & C. Miles -- Genitourinary tract / R. Gardiner -- External genitalia in the male / A. Costello -- Principles and practice of cardiac surgery / J. Tatoulis & J.A. Smith -- Common topics in thoracic surgery / J.A. Smith -- Chronic constipation / Y.H. Ho -- Faecal incontinence / J.J. Tjandra -- Rectal bleeding / J.J. Tjandra -- Haematemesis and melaena / R.J.S. Thomas -- Obstructive jaundice / D. Fletcher -- The acute abdomen / M. Levitt -- The appendix and Meckel's diverticulum / J.J. Tjandra -- Tumours of the small bowel / J.J. Tjandra -- Colorectal cancer and adenoma / J.J. Tjandra -- Diverticular disease of the colon / J.J. Tjandra -- Inflammatory bowel disease / J.J. Tjandra -- Radiation injuries to the small and large bowel / M.J. Soloman & J.J. Tjandra -- Enterocutaneous fistula / J.J. Tjandra -- Rectal prolapse / J.J. Tjandra -- Intestinal stomas / J.J. Tjandra -- Anal and perianal disorders / L. Bokey, P. Chapuis & J.J. Tjandra -- Breast surgery / J.J. Tjandra & J.P. Collins -- Thyroid / L. Delbridge -- Parathyroid / L. Delbridge & G. Clunie -- Tumours of the adrenal gland / L. Delbridge -- Endocrine tumours of the pancreas / G.J.A. Clunie -- Eye injuries and infections / J.E.K. Galbraith -- Otorhinolaryngology / S. O'Leary & V. Vallance -- Tumours of the head and neck / R.T. Judson -- Hernias / D.M.A. Francis -- Tumours and cysts of the skin / G.J.A. Clunie & P. Devitt -- Soft tissue tumours / J.W. Serpell -- Infections of the extremities / D.M.A. Francis --
  • 2015 ClinicalKey
    [edited by] Francis H. Shen, Dino Samartzis, Richard G. Fessler.
    Cervical spine anatomy -- Approaches to the upper cervical spine -- Anterior surgical approach to the cervical spine -- Posterior surgical approach to the cervical spine -- Anterior approaches and surgical considerations for pathology of the cervicothoracic junction -- Developmental and congenital disorders of the cervical spine -- Biomechanics of the cervical spine -- Evaluation of the cervical spine -- Radiographic and computed tomography evaluation of the cervical spine -- Magnetic resonance imaging of the cervical spine -- Neurophysiologic monitoring of the cervical spine -- Cervical degenerative disk disease -- Cervical radiculopathy -- Cervical spondylotic myelopathy -- Cervical deformity and treatment algorithms -- Ossification of the posterior longitudinal ligament -- Occipitocervical and upper cervical spine fractures -- Subaxial cervical spine injuries -- Spinal cord injuries and syndromes -- Traumatic arterial injuries : diagnosis and management -- Stingers and transient paresis -- Primary tumors of the spinal cord -- Primary bony tumors of the cervical spine -- Metastatic disease of the cervical spine -- Infections of the cervical spine -- Tuberculosis of the cervical spine -- Rheumatoid arthritis of the cervical spine -- Ankylosing spondylitis of the cervical spine -- Syringomyelia -- Anterior cervical diskectomy and fusion -- Anterior cervical corpectomy and fusion and hybrid techniques -- Cervical disk arthroplasty -- Anterior cervical foraminotomy -- Laminectomy and fusion -- Cervical laminoplasty -- Posterior cervical endoscopic laminoforaminotomy -- Osteotomies of the cervical spine -- Occipitocervical fixation -- C1 lateral mass and C2 pedicle screw fixation -- C1-C2 transarticular screws -- C2 translaminar screw fixation -- Cervical pedicle screws -- Lateral mass screws -- Interspinous wiring -- Minimally invasive techniques in the cervical spine -- Image-guided navigation for cervical spine surgery -- Biologics for intervertebral disk regeneration and repair -- Biologics for spinal fusion -- Intervertebral disk transplantation -- Vascular injuries -- Spinal cord and nerve injuries in the cervical spine -- Tracheoesophageal injuries -- Dural tear -- Wound complications -- Adjacent segment disease -- Nonunions and implant failures of the cervical spine.
  • 2011 Springer
    Aage R. Møller, Berthold Langguth, Dirk De Ridder, Tobias Kleinjung, editors.
  • 2011 PsychiatryOnline
    edited by Jonathan M. Silver, Thomas W. McAllister, Stuart C. Yudofsky.
    As soldiers and combat veterans have returned from the wars in Iraq and Afghanistan traumatic brain injury (TBI) has been identified as the "signature injury" of those wars. TBI is also in the news on a daily basis due to sports injuries. This new edition has been revised and updated from the 2005 first edition to reflect the exponential expansion of research and clinical data amassed in the intervening years. Each chapter was written and reviewed by the foremost authorities in neuropsychiatry, neurology, rehabilitation medicine, and the other specialties who assess, diagnose, and treat these patients. The revisions and additions to this comprehensive volume were made to ensure that the scope and coverage is both up-to-date and down-to-earth. Key features include: New chapters on epidemiology, neuropathology, and genetics of TBI; new chapter on TBI in the military emphasizing the unique feature of blast injury; A new chapter on posttraumatic stress disorder (PTSD), which emphasizes the common co-occurrence of TBI and PTSD in both combat and other settings; Enhanced coverage of psychopharmacology and psychotherapy for the psychiatric symptoms associated with TBI; Information on the social ramifications of TBI so that clinicians will better understand and help their patients cope with the complex legal, financial, and insurance-based struggles their patients who have sustained TBI encounter; Each chapter concludes with essential points and key references to focus attention and consolidate learning; A foreword written by Bob Woodruff (the ABC World News correspondent who sustained a TBI while covering the war in Iraq) and his wife, Lee Woodruff, who underscore that although this volume is intended to be read primarily by professionals, patients and families may also find the information in the textbook to be of keen interest and practical application.
  • 2006
    editors, Derek Raghavan ... [et al.].
    Status: Not Checked OutLane Catalog Record
    Uncommon tumors of the kidney -- Uncommon cancers of the bladder -- Urethral cancer -- Uncommon cancers of the prostate -- Rare tumors of the testis and paratesticular tissues -- Uncommon tumors of the oral cavity and adjacent structures -- Rare tumors of the larynx -- Nasopharyngeal carcinoma in non-endemic populations -- Esthesioneuroblastoma -- Neoplastic disorders of the adrenal glands -- Uncommon cancers of the thyroid -- Parathyroid carcinoma -- Metaplastic breast carcinoma -- Adenoid cystic carcinoma of the breast -- Non-Hodgkin lymphoma of the breast -- Male breast cancer -- Phyllodes tumor of the breast -- Carcinosarcoma of the breast -- Tubular carcinoma -- Thymoma and thymic carcinoma -- Primary lymphomas of the lung -- Primary sarcomas of the lung -- Mesotheliomas -- Primary melanoma of the lung -- Large cell neuroendocrine -- Carcinoid tumors of the lung -- Bronchioloalveolar carcinoma of the lung -- Primary adenoid cystic carcinoma of the lung -- Mucoepidermoid tumors of the lung -- Uncommon cancers of the esophagus -- Uncommon cancers of the stomach -- Unusual pancreatic tumors -- Uncommon hepatobiliary tumors -- Cancer of the small bowel -- Unusual tumors of the colon, rectum and anus -- Cancer of the appendix -- Gastrointestinal stromal tumors -- Small cell carcinomas of the gastrointestinal tract -- Extra-ovarian primary peritoneal carcinomas -- Borderline tumors and other rare epithelial tumors of the ovary -- Stromal tumors of the ovary -- Germ cell tumors of the ovary -- Fallopian tube cancer -- Uterine sarcomas and unusual endometrial carcinomas -- Tumors of the cervix -- Tumors of the vulva and vagina -- Gestational trophoblastic diseases -- Rare leukemias -- Rare lymphomas -- Uncommon presentations of plasma cell dyscrasias -- Unusual cutaneous malignancies -- Dermatofibrosarcoma protuberans -- Merkel cell carcinoma -- Melanotic lesions of the meninges -- Langerhans' cell histiocytosis of the central nervous system -- Chordomas -- Meningeal sarcomas -- Atypical and malignant meningiomas -- Primary intracranial germ cell tumors -- Primary central nervous system lymphoma -- Choroid plexus papilloma and carcinoma -- Glioma and other neuroepithelial neoplasms -- Medulloblastoma and CNS primitive neuroectodermal tumors -- Craniopharyngiomas -- Ophthalmic cancers -- Rare pediatric malignancies of the head and neck -- Uncommon pediatric tumors of the thorax -- Uncommon tumors of the gastrointestinal tract in children -- Uncommon pediatric genitourinary tumors -- Uncommon endocrine tumors in children and adolescents -- Uncommon pediatric brain tumors -- Malignant tumors of the skin and subcutaneous tissue in children.
  • 2008
    N. Reed Dunnick, Carl M. Sandler, Jeffrey H. Newhouse, E. Stephen Amis, Jr.
    Status: Not Checked OutLane Catalog Record
    Anatomy and embryology -- Congenital anomalies -- Diagnostic techniques -- Functional renal anatomy, renal physiology, and contrast management -- The retroperitoneum -- The adrenal gland -- Renal cystic disease -- Renal tumors -- Renal inflammatory disease -- Vascular diseases -- Renal hypertension -- Renal failure and medical renal disease -- Renal transplantation -- Nephrocalcinosis and nephrolithiasis -- Pelvicalyceal system and ureter -- The urinary bladder -- Prostate and seminal vesicles -- Urethra and penis -- Scrotum and contents -- Urinary tract trauma -- Female genital tract.
  • 1953-
    by A.J. Rhodes and C.E. van Rooyen.
    Status: Not Checked OutLane Catalog Record
  • v. 1-4, 1950-51.
    by British authors ; edited by S. Cochrane Shanks and Peter Kerley.
    Status: Not Checked OutLane Catalog Record
    v. 1. Head and neck -- v. 2. Chest -- v. 3. Abdomen -- v. 4. Bones, joints and soft tissues.
  • 2013 Springer
    Aristidis Moustakas, Keiji Miyazawa, editors.
  • 2016 Springer Protocols
    edited by Xin-Hua Feng, Pinglong Xu, Xia Lin.
    Regulation of TGF-beta receptors / Erine H. Budi, Jian Xu, and Rik Derynck -- 2 Determining TGF-beta receptor levels in the cell membrane / Long Zhang ... [et al.] -- Posttranslational modifications of TGF-beta receptors / Xiaohua Yan and Ye-Guang Chen -- Production, isolation, and structural analysis of ligands and receptors of the TGF-beta superfamily / Tao Huang and Andrew P. Hinck -- Phosphorylation of Smads by intracellular kinases / Fang Liu and Isao Matsuura -- Analysis of Smad phosphatase activity in vitro / Tao Shen, Lan Qin, and Xia Lin -- Three-dimensional mammary epithelial cell morphogenesis model for analysis of TGFbeta signaling / Juliet Rashidian and Kunxin Luo -- TGF-beta signaling in stem cell regulation / Wenlin Li, Wanguo Wei, and Sheng Ding -- Analysis of epithelial-mesenchymal transition induced by transforming growth factor beta / Ulrich Valcourt ... [et al.] -- In vitro Th differentiation protocol / Takashi Sekiya and Akihiko Yoshimura -- Interrogating TGF-beta function and regulation in endothelial cells / J. A. Maring ... [et al.] -- Isolation and manipulation of adipogenic cells to assess TGF-beta superfamily functions / Maria Namwanje, Juan C. Bournat, and Chester W. Brown -- Imaging TGF-beta signaling in mouse models of cancer metastasis / Yibin Kang -- Generation and characterization of Smad7 conditional knockout mice / Yi Pan and Yan Chen -- Monitoring Smad activity in vivo using the Xenopus model system / Marco Montagner, Graziano Martello, and Stefano Piccolo -- Animal cap assay for TGF-beta signaling / Chenbei Chang -- Detection of Smad signaling in Zebrafish embryos / Xingfeng Liu, Qiang Wang, and Anming Meng -- Role of TGF-beta signaling in coupling bone remodeling / Janet L. Crane, Lingling Xian, and Xu Cao -- Studying the functions of TGF-beta signaling in the ovary / Chao Yu, Jian-Jie Zhou, and Heng-Yu Fan -- Quantitative real-time PCR analysis of MicroRNAs and their precursors regulated by TGF-beta signaling / Hara Kang and Akiko Hata -- TGF-beta-regulated MicroRNAs and their function in cancer biology / Pengyuan Yang ... [et al.] -- Epigenomic regulation of Smad1 signaling during cellular senescence induced by Ras activation / Atsushi Kaneda ... [et al.] -- Role of ubiquitination to Determine non-Smad signaling responses / Shyam Kumar Gudey and Marene Landström -- Genome-wide RNAi screening to dissect the TGF-beta signal transduction pathway / Xiaochu Chen and Lan Xu -- Measuring TGF-beta ligand dynamics in culture medium / Zipei Feng , Zhike Zi , and Xuedong Liu.
  • 2009 Springer
    Valérie Quesniaux, Bernhard Ryffel, Franco Di Padova, editors.
    Also available: Print – 2009
  • 2011 Springer
    Shiuping Jiang, editor.
  • Mlodinow, Leonard.
    Status: Not Checked OutLane Catalog Record
  • v. 1-2, 2007.
    Edward G. Jones.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer Protocols
    edited by Ari Waisman, Burkhard Becher.
    Isolation of T cells from the skin / Beate Lorenz and Esther von Stebut -- Isolation of leukocytes from mouse central nervous system / Iva Lelios and Melanie Greter -- Isolation of T cells from the gut / Sonja Reissig, Christopher Hackenbruch, and Nadine Hövelmeyer -- T cell isolation from mouse kidneys/ Isis Ludwig-Portugall and Christian Kurts -- Intracellular staining for cytokines and transcription factors / Florian Mair and Vinko Tosevski -- Tracking cells and monitoring proliferation / Vinko Tosevski and Florian Mair -- Mass cytometry analysis of human T cell phenotype and function / Evan W. Newell and Lai Li Yun -- Detection of NF-[kappa]B pathway activation in T helper cells / Oliver Gorka, Stefan Wanninger, and Jürgen Ruland -- Assessing the suppressive activity of Foxp3⁺ regulatory T cells / Christian Thomas Mayer and Tim Sparwasser -- In vitro generation of microbe-specific human Th17 cells / Julia M. Braun and Christina E. Zielinski -- In vitro polarization of T-helper cells / Julie Rumble and Benjamin M. Segal -- A method for the generation of TCR retrogenic mice / Elisa Kieback, Ellen Hilgenberg, and Simon Fillatreau -- Mouse models of allergic airway disease / Helen Meyer-Martin, Sebastian Reuter, and Christian Taube -- Induction of colitis in mice (T-cell transfer model) / Benno Weigmann -- Manipulation of T cell function and conditional gene targeting in T cells / Anna Śledzińska,Lynsey Fairbairn, and Thorsten Buch -- Aldara-induced psoriasis-like skin inflammation : Isolation and characterization of cutaneous dendritic cells and innate lymphocytes / C.T. Wohn ... [et al.] -- Induction of passive EAE using myelin-reactive CD4+ T cells / Rhoanne C. McPherson ... [et al.] -- Experimental mouse models of T cell-dependent inflammatory bowel disease / George X. Song-Zhao and Kevin J. Maloy -- Analysis of chromosomal aberrations in murine HCC / Kristian Unger and Mathias Heikenwälder.
  • 2012
    Matthew Gene Davidson.
    In multiple sclerosis and many other autoimmune diseases, activated T-helper (Th) cells colocalize with monocytes and dendritic cells (DC) in the inflamed tissue. Evidence suggests that these activated Th cells may be driving monocytes to differentiate into DC, but this phenomenon has not been explored in vivo. Using various methods of activating T-cells in vivo and the mouse model experimental autoimmune encephalomyelitis (EAE), we investigate how Th cells influence the function and phenotype of nearby monocytes. Using in vivo labeling of monocytes with a commercially available anti-CD209 antibody, we show that T-cell activation induces the rapid formation of monocyte-derived DC (Mo-DC) in lymph nodes. These T-cell driven Mo-DC are capable of robustly stimulating naïve T-cells, but induce little T-cell polarization. Surprisingly, TNF[alpha] but not GM-CSF was required for CD209+ Mo-DC formation after T-cell activation. These findings expand the range of signals capable of driving Mo-DC formation beyond known PAMPS and cytokines to include activated T-cells themselves. We also show that activated bulk Th cells or Th1, Th2 or Th17 subsets, when cultured with autologous monocytes in vitro, promote the formation of MHC II+, CD11b+, CD11c+ Mo-DC that we call DCTh. While all Th subsets tested induced the formation of DCTh, Th17 cells uniquely promoted the formation of IL-12/IL-23 producing Mo-DC with potent Th1 polarizing capacity that we call DCTh17. Further, Th cells isolated from the CNS of mice with Th17 driven EAE, drive robust formation of DCTh that produce IL-12 and polarize naive T-cells toward a Th1 phenotype. These results show that DCTh17 are critical in the interplay of Th17 and Th1 mediated responses in EAE and have implications for the treatment of MS.
  • 2008 Springer
    Shiyi Shen, Jack A. Tuszynski.
  • 2005 CRCnetBASE
    edited by Tapash K. Ghosh, Bhaskara R. Jasti.
    Methods of data representation, interpretation, and analysis / Craig K. Svensson and Tapash K. Ghosh -- Thermodynamics and states of matter / Adam M. Persky, Laszlo Prokai, and Jeffrey A. Hughes -- Solubility / Jeffrey A. Hughes .. [et al.] -- Physiochemical factors affecting biological activity / Hemant Alur ... [et al.] -- Micromeritics and rheology / Sunil S. Jambhekar -- Principles and applications of surface phenomena / Laszlo Prokai ... [et al.] -- Theory and applications of diffusion and dissolution / Xiaoling Li and Bhaskara Jasti -- Chemical kinetics and stability / Tapash K. Ghosh -- Drug and dosage form development: regulatory perspectives / Edward Dennis Bashaw -- Oral conventional solid dosage forms: powders and granules, tablets, lozenges, and capsules / Melgardt M. de Villiers -- Oral controlled release solid dosage forms / Emmanuel O. Akala -- Oral liquid dosage forms: solutions, elixirs, syrups, suspensions, and emulsions / William M. Kolling and Tapash K. Ghosh -- Parenteral routes of delivery / Yon Rojanasakul and Carl J. Malanga -- Transdermal and topical drug delivery systems / Bhaskara R. Jasti, William Abraham, and Tapash K. Ghosh -- Rectal and vaginal routes of drug delivery / Nikhil R. Shitut .. [et al.] -- Ocular, nasal, pulmonary, and otic routes of drug delivery / Harisha Atluri ... [et al.] -- Delivery of peptide and protein drugs / Emily Ha ... [et al.].
  • 2008 ClinicalKey
    [edited by] John D. Bancroft, Marilyn Gamble.
    Also available: Print – 2008
  • 1850-
    Cazeaux, P.; Hess, Robert J.; Tarnier, S.
    Status: Not Checked OutLane Catalog Record
  • 2014 CRCnetBASE
    Eric B. Holmgren.
    Section I. A theory of evaluating drugs -- section II. A theory of evidence in drug development -- section III. Additional topics.
  • 2013 Springer
    Richard P. Baum, Frank Rösch, editors.
  • 2011 Springer
    Mark Slevin, editor.
  • 2008 Springer
    Yuti Chernajovsky, Ahuva Nissim, editors.
  • 2010 Springer
    edited by José Luis Pedraz, Gorka Orive.
    Highlights and trends in cell encapsulation / Gorka Orive and José Luis Pedraz -- Biomaterials in cell microencapsulation / Edorta Santos ... [et al.] -- Development of subsieve size capsules and application to cell therapy / Shinji Sakai and Koei Kawakami -- Regulatory considerations in application of encapsulated cell therapies / J. van Zanten and Paul de Vos -- Treatment of diabetes with encapsulated islets / Paul de Vos, Milica Spasojevic, and Marijke M. Faas -- Epo delivery by genetically engineered C2C12 myoblasts immobilized in microcapsules / Ainhoa Murua ... [et al.] -- Artificial cell microencapsulated stem cells in regenerative medicine, tissue engineering, and cell therapy / Zun Chang Liu and Thomas Ming Swi Chang -- Microencapsulated choroid plexus epithelial cell transplants for repair of the brain / Christopher G. Thanos, Briannan Bintz, and Dwaine F. Emerich -- Therapeutic application of cell microencapsulation in cancer / Brian Salmons and Walter H. Gunzburg -- Inorganic nanoporous membranes for immunoisolated cell-based drug delivery / Adam Mendelsohn and Tejal Desai -- Cell microencapsulation / Grace J. Lim ... [et al.] -- Commercial applicability of cell microancapsulation : a review of intellectual property rights / Stephan M. Meier.
    Also available: Print – 2010
  • 2012 ScienceDirect
    Stephen Neidle.
    "Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. 4 of cover.
  • 2014 Springer Protocols
    edited by Daniel Lafontaine and Audrey Dubé, Department of Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
    Identification of regulatory RNA in bacterial genomes by genome-scale mapping of transcription start sites -- Screening inhibitory potential of anti-HIV RT RNA aptamers -- Design and evaluation of clinically relevant SOFA-HDV ribozymes targeting HIV RNA -- Directing RNase P-mediated cleavage of target mRNAs by engineered external guide sequences in cultured cells -- Design and analysis of hammerhead ribozyme activity against an artificial gene target -- Knockdown strategies for the study of proprotein convertases and proliferation in prostate cancer cells -- Use of tumor-targeting trans-splicing ribozyme for cancer treatment -- Characterization of hairpin ribozyme reactions -- Finding instances of riboswitches and ribozymes by homology search of structured RNA with infernal -- Structure-based virtual screening for the identification of RNA- binding ligands -- Probing riboswitch binding sites with molecular docking, focused libraries, and in-line probing assays -- Discovery of small molecule modifiers of micrornas for the treatment of HCV infection -- Bacterial flavin mononucleotide riboswitches as targets for flavin analogs -- Construction and application of riboswitch-based sensors that detect metabolites within bacterial cells -- Screening assays to identify artificial glmS ribozyme activators -- Analysis of riboswitch structure and ligand binding using small-angle X-ray scattering (SAXS) -- Use of SHAPE to select 2AP substitution sites for RNA-ligand interactions and dynamics studies -- Cell internalization SELEX: In vitro selection for molecules that internalize into cells -- DNA electronic switches based on analyte-responsive aptamers.
  • 2012 ScienceDirect
    2012 ClinicalKey
    edited by Amitava Dasgupta.
    Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presentsssnew and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathol.
  • 2015 Springer
    Hoon Jai Chun, Suk-Kyun Yang, Myung-Gyu Choi, editors.
    This atlas, featuring a wealth of high-quality images, offers a comprehensive overview of therapeutic gastrointestinal endoscopy for upper and lower gastrointestinal diseases. Both established and new therapeutic techniques using advanced endoscopic devices are extensively covered. The concise text accompanying the endoscopic photographs and illustrations will enable readers to understand the details of each procedure. Special tips of practical value are highlighted and potential pitfalls, identified. The authors are experts in the field who have a great store of knowledge on a wide variety of therapeutic endoscopic procedures. Gastrointestinal endoscopy is the principal tool for the investigation and treatment of most diseases of the gastrointestinal tract. This book will provide the clear guidance that practitioners require in order to perform therapeutic gastrointestinal endoscopy optimally; it will prove indispensable for all gastrointestinal endoscopists.
  • 2005 Springer
    edited by Samuel A. Tisherman and Fritz Sterz.
  • 2012 Springer
    Ingo K. Mellinghoff, Charles L. Sawyers, editors.
    Setting up a Kinase Discovery and Development Project / Gideon Bollag -- Drug Efficacy Testing in Mice / William Y. Kim, Norman E. Sharpless -- Gastrointestinal Stromal Tumors / Cristina Antonescu -- EGFR Mutant Lung Cancer / Yixuan Gong, William Pao -- Targeting Oncogenic BRAF in Human Cancer / Christine A. Pratilas, Feng Xing, David B. Solit -- Beyond BRAF in Melanoma / Adil Daud, Boris C. Bastian -- JAK-Mutant Myeloproliferative Neoplasms / Ross L. Levine -- Will Kinase Inhibitors Make it as Glioblastoma Drugs? / Ingo K. Mellinghoff, Nikolaus Schultz, Paul S. Mischel -- Predictive Genomic Biomarkers / Rakesh Kumar, Rafael G. Amado -- Epigenetic Biomarkers / Timothy A. Chan, Stephen B. Baylin -- Adjuvant Trials of Targeted Agents: The Newest Battleground in the War on Cancer / Robert L. Cohen.
    Also available: Print – 2012
  • 2007 Springer
    edited by Michael H. Davidson, Peter P. Toth, Kevin C. Maki ; foreword by Antonio M. Gotto Jr.
  • 2008 Springer
    J. Haslam and J. Laycock (eds).
  • 2007 Springer
    edited by Elisabeth Deindl and Christian Kupatt.
  • 2014 Springer
    Richard P. Baum, editor.
    The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. The selective irradiation of tumor cells through molecular biological mechanisms is now permitting the radiopharmaceutical control of tumors that are unresectable and unresponsive to either chemotherapy or conventional radiotherapy. In this up-to-date, comprehensive book, world-renowned experts discuss the basic principles of radionuclide therapy, explore in detail the available treatments, explain the regulatory requirements, and examine likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the important role of the therapeutic nuclear physician in delivering the effective coordination of a diverse multidisciplinary team that is essential to the safe provision of treatment.
  • 2011 Springer Protocols
    edited by John Goodchild.
    Therapeutic oligonucleotides / John Goodchild -- Dinucleotides containing 3-S-phosphorothiolate linkages / James W. Gaynor and Richard Cosstick -- 2-O,4-C-methyleneoxymethylene bridged nucleic acids (2,4-BNACOC) / Yoshiyuki Hari [and others] -- Non-covalent peptide-based strategy for ex vivo and in vivo oligonucleotide delivery / Laurence Crombez [and others] -- Cell-penetrating peptides-based strategies for the delivery of splice redirecting antisense oligonucleotides / Samir El Andaloussi [and others] -- Nanoparticle for tumor targeted delivery of oligomers / Xinrong Liu, Yi Wang, and Donald J. Hnatowich -- Light-directed delivery of nucleic acids / Sigurd Bøe [and others] -- Antibody targeted siRNA delivery / Masoud M. Toloue and Lance P. Ford -- Aptamer-drug conjugation for targeted tumor cell therapy / Michael J. Donovan [and others] -- Five-step process for screening antisense compounds for efficacy: gene target IL-12Rb2 / Nikki B. Marshall, Laura L. Hauck, and Dan V. Mourich -- Diverse small non-coding RNAs in RNA interference pathways / Liande Li and Yi Liu -- Quantification of siRNAs in vitro and in vivo / Angie Cheng, Alexander V. Vlassov, and Susan Magdaleno -- Optimization of transfection conditions and analysis of siRNA potency using real-time PCR / Angie Cheng, Susan Magdaleno, and Alexander V. Vlassov -- siRNA knockdown of gene expression in endothelial cells / Emily Dennstedt and Brad Bryan -- Using RNA interference in Schistosoma mansoni / Rita Bhardwaj, Greice Krautz-Peterson, and Patrick J. Skelly -- Performing the labeled microRNA pull-down (LAMP) assay system : an experimental approach for high-throughput identification of microRNA-target mRNAs / Ren-Jun Hsu and Huai-Jen Tsai -- Synthesis, purification, and characterization of oligoribonucleotides that act as agonists of TLR7 and/or TLR8 / Tao Lan and Ekambar R. Kandimalla -- Synthesis, purification, and characterization of immune-modulatory oligodeoxynucleotides that act as agonists of toll-like receptor 9 / Mallikarjuna Reddy Putta, Dong Yu, and Ekambar R. Kandimalla -- Surface plasmon resonance investigation of RNA aptamer-RNA ligand interactions / Carmelo Di Primo, Eric Dausse, and Jean-Jacques Toulme -- Practical considerations for analyzing antigene RNAs (agRNAs) : RNA immunoprecipitation of argonaute protein / Jacob C. Schwartz and David R. Corey -- Inhibition of human papillomavirus expression using DNAzymes / Maria Luisa Benitez-Hess, Pablo Reyes-Gutierrez, and Luis Marat Alvarez-Salas.
  • 2014 Springer Protocols
    edited by Andrew E. Nixon.
    Design of phage-displayed cystine-stabilized mini-protein libraries for proteinaceous binder engineering / Hung-Ju Chang and An-Suei Yang -- Construction of a filamentous phage display peptide library / Annette Fagerlund, Astrid Hilde Myrset, and Mari Ann Kulseth -- Engineering bioactive peptide-based therapeutic molecules / Jong Sang Ryu [and three others] -- T7 lytic phage-displayed peptide libraries : construction and diversity characterization / Lauren R.H. Krumpe and Toshiyuki Mori -- Affinity selection using filamentous phage display / Mari Ann Kulseth, Annette Fagerlund, and Astrid Hilde Myrset -- Bioprospecting open reading frames for peptide effectors / Ling Xiong and Charles Scott -- Identification of ideal peptides for heterovalent ligands / Ajay Shrivastava [and three others] -- Substrate phage display for protease substrate sequence characterization : bovine factor Xa as a model system / Hung-Ju Hsu and An-Suei Yang -- Engineering peptide therapeutics using MIMETIBODY [trademark] technology / Kristen Picha [and three others] -- Evaluation of peptides as protease inhibitors and stimulators / Hannu Koistinen [and four others] -- Assessment of antimicrobial (host defense) peptides as anti-cancer agents / Susan Douglas, David W. Hoskin, and Ashley L. Hilchie -- Peptide labelling strategies for imaging agents / Tuulia Huhtal [and three others] -- Peptide optimization and conjugation strategies in the development of molecularly targeted magnetic resonance imaging contrast agents / Andrew F. Kolodziej [and four others] -- Evaluation of prenylated peptides for use in cellular imaging and biochemical analysis / Joshua D. Ochocki [and five others] -- Ultraviolet absorption spectroscopy of peptides / Mangala R. Liyanage [and three others] -- Fluorescence spectroscopy of peptides / Mangala R. Liyanage [and three others] -- Circular dichroism of peptides / Kunal Bakshi [and three others] -- Fourier transform infrared spectroscopy of peptides / Kunal Bakshi [and three others].
  • 2006 CRCnetBASE
    Ajay K. Banga.
  • 2012 Springer Protocols
    edited by Vladimir Voynov, Justin A. Caravella.
    Therapeutic proteins / Dimiter S. Dimitrov -- Synthetic antibody libraries / Bryce Nelson and Sachdev S. Sidhu -- Construction of "phylomer" peptide libraries as a rich source of potent inhibitors of protein/protein interactions / Nadia Milech and Paul Watt -- Ribosome display and screening for protein therapeutics / Damjana Kastelic and Mingyue He -- Yeast display of engineered antibody domains / Qi Zhao, Zhongyu Zhu, and Dimiter S. Dimitrov -- Expression, purification, and characterization of engineered antibody CH2 and VH domains / Rui Gong, Weizao Chen, and Dimiter S. Dimitrov -- Engineering of affibody molecules for therapy and diagnostics / Joachim Feldwisch and Vladimir Tolmachev -- Protein design for diversity of sequences and conformations using dead-end elimination / Karl J.M. Hanf -- Design and generation of DVD-Ig(TM) molecules for dual-specific targeting / Enrico DiGiammarino, Tariq Ghayur, and Junjian Liu -- Engineering and expression of bibody and tribody constructs in mammalian cells and in the yeast Pichia pastoris / Steve Schoonooghe -- Use of E. coli for the production of a single protein / Lili Mao and Masayori Inouye -- Folding engineering strategies for efficient membrane protein production in E. coli / Brent L. Nannenga and François Baneyx -- Transient expression technologies : past, present, and future / Sabine Geisse and Bernd Voedisch -- Stable transfection pools for large quantity of protein production / Jianxin Ye -- Mammalian stable expression of biotherapeutics / Thomas Jostock and Hans-Peter Knopf -- Transgenic expression of therapeutic proteins in Arabidopsis thaliana seed / Cory L. Nykiforuk and Joseph G. Boothe -- Methods for chromatographic removal of endotoxin / Adam J. Lowe, Cameron L. Bardliving, and Carl A. Batt -- Effectiveness of various processing steps for viral clearance of therapeutic proteins : database analyses of commonly used steps / Dana Cipriano, Michael Burnham, and Joseph V. Hughes -- High-throughput quantitative N-glycan analysis of glycoproteins / Margaret Doherty [and others] -- High-throughput multimodal strong anion exchange purification and N-glycan characterization of endogenous glycoprotein expressed in glycoengineered Pichia pastoris / Sujatha Gomathinayagam [and others] -- Databases and tools in glycobiology / Natalia V. Artemenko [and others] -- Characterization of PEGylated biopharmaceutical products by LC/MS and LC/MS/MS / Lihua Huang and P. Clayton Gough -- Identification of asp isomerization in proteins by ¹⁸O labeling and tandem mass spectrometry / Jennifer Zhang and Viswanatham Katta -- Monitoring of subvisible particles in therapeutic proteins / Satish K. Singh and Maria R. Toler -- Size-exclusion chromatography with multi-angle light scattering for elucidating protein aggregation mechanisms / Erinc Sahin and Christopher J. Roberts -- Computational methods to predict therapeutic protein aggregation / Patrick M. Buck [and others] -- Coarse-grained simulations of protein aggregation / Troy Cellmer and Nicolas L. Fawzi -- Chitosan-based nanoparticles as delivery systems of therapeutic proteins / Pedro Fonte [and others] -- Challenges in the development and manufacturing of antibody-drug conjugates / Laurent Ducry.
  • 2013
    Martin Halliwell.
    "Therapeutic Revolutions examines the evolving relationship between American medicine, psychiatry, and culture from World War II to the dawn of the 1970s. In this richly layered intellectual history, Martin Halliwell ranges from national politics, public reports, and healthcare debates to the ways in which film, literature, and the mass media provided cultural channels for shaping and challenging preconceptions about health and illness. Beginning with a discussion of the profound impact of World War II and the Cold War on mental health, Halliwell moves from the influence of work, family, and growing up in the Eisenhower years to the critique of institutional practice and the search for alternative therapeutic communities during the 1960s. Blending a discussion of such influential postwar thinkers as Erich Fromm, William Menninger, Erving Goffman, Erik Erikson, and Herbert Marcuse with perceptive readings of a range of cultural text that illuminate mental health issues--among them Spellbound, Shock Corridor, Revolutionary Road, and I Never Promised You a Rose Garden--this compelling study argues that the postwar therapeutic revolutions closely interlink contrasting discourses of authority and liberation." -- Publisher's website.
  • 2009 Springer
    Volker A. Erdmann, Guido Reifenberger, Jan Barciszewski, editors.
  • 2016 Springer
    Thomas Platz, editor.
    Neurophysiology of rTMS -- Brain imaging ? network effects of rTMS -- Basic principles of rTMS in motor recovery after stroke -- Clinical applications of rTMS in motor rehabilitaton after stroke -- rTMS in dysphagia after stroke -- Basic principles of rTMS in aphasia treatment after stroke -- Therapeutic applications of rTMS for aphasia after stroke -- rTMS in visual neglect after stroke -- Clinical applications of rTMS in Parkinson?s disease -- rTMS in the treatment of neuropathic pain -- Therapeutic applications of rTMS for tinnitus -- General concepts of therapeutic rTMS in neurology.
  • 2013 ScienceDirect
    Gajanan V. Sherbet.
    Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination.
  • 2014 ScienceDirect
    Eyal Lederman DO, PHD, director, Centre for Professional Development in Manual and Physical Therapies ; Senior Lecturer, University College London (UCL), London, UK.
    Introduction to therapeutic and functional stretching -- Functional and dysfunctional ROM -- Causes of ROM loss and therapeutic potential of rehabilitation -- Adaptation in ROM loss and recovery -- Specificity in ROM rehabilitation -- The overloading condition for recovery -- Exposure and scheduling the ROM challenge -- Rehabilitating the active ROM : neuromuscular rehabilitation -- Pain management and ROM-desensitization -- Stretch tolerance model -- Psychological and behavioral considerations in ROM rehabilitation -- Towards a functional approach -- Demonstration of functional approach in ROM rehabilitation
  • 2009 Springer
    edited by Iqbal S. Grewal.
    Overview of TNF superfamily : a chest full of potential therapeutic targets / Iqbal S. Grewal -- Therapeutic interventions targeting CD40l (CD154) and CD40 : the opportunities and challenges / Che-Leung Law and Iqbal S. Grewal -- Targeting TNF for treatment of cancer and autoimmunity / Gautam Sethi ... [et al.] -- Targeting of BAFF and APRIL for autoimmunity and oncology / Maureen C. Ryan and Iqbal S. Grewal -- The role of FASL and FAS in health and disease / Martin Ehrenschwender and Harald Wajant -- OX40 (CD134) and OX401 / Michael J. Gough and Andrew D. Weinberg -- Targeting CD70 for human therapeutic use / Tamar Boursalian ... [et al.] -- 4-1BB as a therapeutic target for human disease / Seung-Woo Lee and Michael Croft -- Rank(l) as a key target for controlling bone loss / Andreas Leibbrandt and Josef M. Penninger -- Targeting the light-HVEM pathway / Carl F. Ware -- GITR : a modulator of immune response and inflammation / Giuseppe Nocentini and Carlo Riccardi -- Targeting CD30/CD30l in oncology and autoimmune and inflammatory diseases / Ezogelin Oflazoglu, Iqbal S. Grewal, and Hans Peter Gerber -- Tumor necrosis factor receptor superfamily member 21 : TNFR-related death receptor-6, DR6 / Robert Benschop, Tao Wei, and Songqing Na -- TRAIL and other TRAIL receptor agonists as novel cancer therapeutics / Christina Falschlehner ... [et al.] -- Therapeutic potential of VEGI/TL1A -- In autoimmunity and cancer / Gautam Sethi, Bokyung Sung, and Bharat B. Aggarwal.
    Also available: Print – 2009
  • 2016 Springer
    Jean-Michel Escoffre, Ayache Bouakaz, editors
    Part I -- High Intensity Focused Ultrasound Ablation of Pathological Tissue -- Chapter 1. HIFU Tissue Ablation: Concept & Devices G. Ter Haar -- Chapter 2. Prostate Focused Ultrasound Therapy J.Y. Chapelon, O. Rouvière, S. Crouzet, A. Gelet -- Chapter 3. MRI-guided HIFU Methods for the Ablation of Liver and Renal Cancers B.D. de Senneville, C. Moonen, M. Ries -- Chapter 4. Magnetic Resonance-guided High Intensity Focused Ultrasound Ablation of Breast Cancer -- F.M. Knuttel, M.A.A.J. van den Bosch -- Chapter 5. HIFU for Palliative Treatment of Pancreatic Cancer -- T.D. Khokhlova, J.H. Hwang -- Chapter 6. MR-guided Transcranial Focused Ultrasound -- J.F. Aubry, M. Tanter -- Chapter 7. Focused Ultrasound & Lithotripsy -- T. Ikeda, S. Yoshizawa, N. Koizumi, M. Mitsuishi, Y. Matsumoto -- Chapter 8. Heat-based Tumor Ablation: Role of the Immune Response F. Wu -- Part II -- Drug and Gene Delivery using Bubble-assisted Ultrasound -- Chapter 9. Droplets, Bubbles and Ultrasound Interactions O. Shpak, M. Verweij, N. de Jong, M. Versluis -- Chapter 10. Sonoporation: Concept and Mechanisms A. Bouakaz, A. Zeghimi, A.A. Doinikov -- Chapter 11. Design of Microbubbles for Gene/Drug Delivery T. Bettinger, F. Tranquart -- Chapter 12. Co-administration of Microbubbles and Drugs in Ultrasound-assisted Drug Delivery: Comparison with Drug-carrying Particles R. Suzuki, A.L. Klibanov -- Chapter 13. Drug-loaded Perfluorocarbon Nanodroplets for Ultrasound-mediated Drug delivery N. Rapoport -- Chapter 14. Bubble-assisted Ultrasound: Application in Immunotherapy and Vaccination J.M. Escoffre, R. Deckers, C. Bos, C. Moonen -- Chapter 15. Sonoporation: Application for Cancer Therapy -- J. Qin, T.Y. Wang, J.K. Willmann -- Chapter 16. Microbubble-assisted Ultrasound for Drug Delivery in the Brain and Central Nervous System A. Burgess, K. Hynynen -- Chapter 17. Microbubbles & Ultrasoun: Therapeutic Applications in Diabetic Nephropathy W.J. Cao, P.N. Matkar, H.H. Chen, A. Mofid, H. Leong-Poi -- Chapter 18. Drug and Gene Delivery using Sonoporation for Cardiovascular Disease J. Castle, S.B. Feinstein -- Chapter 19. Sonothrombolysis K.B. Bader, G. Bouchoux, C.K. Holland -- Part III- Other Ultrasound Therapy -- Chapter 20. Ultrasound-mediated Polymeric Micelle Drug Delivery H. Xia, Y. Zhao, R. Tong -- Chapter 21. Stimulation of Bone Repair with Ultrasound -- F. Padilla, R. Puts, L. Vico, A. Guignadon, K. Raum -- Chapter 22. Sonodynamic Therapy: Concept, Mechanism & Application to Cancer Treatment A.P. McHale, J.F. Callan, N. Nomikou, C. Fowley, B. Callen.
    Also available: Print – 2016
  • 2014 Springer
    Beatriz Caiuby Labate, Clancy Cavnar, editors.
    This book presents a series of perspectives on the therapeutic potential of the ritual and clinical use of the Amazonian hallucinogenic brew ayahuasca in the treatment and management of various diseases and ailments, especially its role in psychological well-being and substance dependence. Biomedical and anthropological data on the use of ayahuasca for treating depression, PTSD, and substance dependence in different settings, such as indigenous contexts, neo-shamanic rituals, contemporary therapeutic circles, and in ayahuasca religions, in both South and North America, are presented and critiqued. Though multiple anecdotal reports on the therapeutic use of ayahuasca exist, there has been no systematic and dense reflection on the topic thus far. The book brings the therapeutic use of ayahuasca to a new level of public examination and academic debate. The texts in this volume stimulate discussion on methodological, ethical, and political aspects of research and will enhance the development of this emergent field of studies.
  • 2007 Springer
    edited by Grant Cooper.
  • 2014 Springer
    Enqiang Linghu, editor.
    This book elaborates on a whole new understanding of digestive endoscopy, the core of which is to treat quite a number of diseases using minimally invasive methods, provides the walls of the digestive tube are free of perforations. Currently, the tunnel technique has been applied in the treatment of digestive early stage carcinomas, esophageal achalasia and submucosal tumors originating from muscularis propria. And this promising technique would surely be more widely used in the future. The main contents of this book include the history of the digestive endoscopic tunnel technique, the practical anatomy involved, operation steps, indications and contraindications, complications and possible future exploration fields. This book is well suited for doctors and surgeons performing digestive endoscopic therapies.
  • 2008 Springer
    [edited by] Sandrine Faivre, Eric Raymond.
  • 2007 Springer
    J. Wacker ... [et al.] ; mit einem Geleitwort von D. Ganten.
  • 2008 Springer
    [edited by] Gaëtan des Guetz, Jean-Yves Blay.
  • 2013
    [edited by] Anne J. Adelman and Kerry L. Malawista.
    "For therapists caught between their grief and the empathy they provide for their clients, this collection explores the complexity of bereavement within the practice setting. It also examines the professional and personal ramifications of death and loss for the practicing clinician. Featuring original essays from longstanding practitioners, the collection demonstrates the universal experience of bereavement while outlining a theoretical framework for the position of the bereft therapist. Essays cover the unexpected death of clients and patient suicide, personal loss in a therapist's life, the grief of clients who lose a therapist, disastrous loss within a community, and the grief resulting from professional losses and disruptions." -- [Publisher-supplied data]
  • 2012 Springer
    Dawn A. Marcus.
    Cancer Overview -- Introduction to Therapy Dogs -- Dogs as Cancer Detectors -- Dog Therapy with Cancer Treatment -- Adding Therapy Dogs to Your Cancer Treatment Team -- Incorporating Companion Dogs into Cancer Rehab: Emotional Support -- Incorporating Companion Dogs into Cancer Rehab: Benefits from Physical Exercise for Cancer Patients -- Incorporating Companion Dogs into Cancer Rehab: Dog-Themed Exercise Program for Cancer Patients -- Incorporating Companion Dogs into Cancer Rehab: Practical Tips for Adding a Dog into the Home During Cancer Treatment and Recovery -- Resources.
  • 2008 ClinicalKey
    [edited by] Christopher S. Wilcox ; section editors, Tomas Berl ... [et al.].
    Also available: Print – 2008
  • 2012 ScienceDirect
    2012 ClinicalKey
    Teri J. Barkoukis, Jean K. Matheson, Richard Ferber, Karl Doghramji.
    Introduction to sleep medicine -- Background to sleep medicine therapeutics -- Pharmacology principles -- Insomnias -- Sleep-related breathing disorders -- Central hypersomnolence -- Movement disorders affecting sleep -- Circadian rhythm disorders -- Therapy in pediatric sleep-related disorders -- Parasomnias in adults -- Sleep-related medical disorders -- Neurologic disorders and sleep -- Therapy of sleep disturbances associated with psychiatric disorders -- Special situations and the future -- Appendix: Effects of drugs on sleep.
  • 2010 Springer
    Thomas Krieg, David R. Bickers, Yoshiki Miyachi (eds.).
  • 2015 Springer
    Scott F. M. Duncan, Christopher W. Flowers.
    Presenting over 100 rehabilitation protocols for the hand and upper extremity in an easy-to-use, step-by-step format, this practical reference provides surgeons and therapists alike with a go-to source for the therapy technique or strategy appropriate for their patients. Covering injuries from the shoulder, elbow, wrist, hand and fingers, each protocol includes bullet-pointed steps in daily or weekly increments following the injury or surgery and are inherently adaptable to the specific surgical intervention or rehabilitation requirement. Procedures following arthroplasty, extensor and flexor tendon injuries, fractures and dislocations, ligament and soft tissue injures, and nerve compression syndromes are among the many and multifaceted therapies presented. This book will be an invaluable resource for the orthopedic surgeon, hand surgeon, physical therapist, occupational therapist, hand therapist and any active clinician treating injuries to the hand and upper extremity.
  • 2010 CRCnetBASE
    Howard Green.
    Cultured cells for therapy are now being prepared by industries in the US, Japan and Korea and are used in the aforesaid countries as well as France, Sweden and Greece, for the treatment of disease. This title describes the discoveries in the author's laboratory that led to therapy with cultured cells.
  • 2010 Karger
    volume editors, Hélio Elkis, Herbert Y. Meltzer.
    History and current definition of treatment resistant schizophrenia / Helio Elkis -- Assessment of therapy resistant schizophrenia / Jean Pierre Lindenmayer -- Neuropsychology of treatment resistant schizophrenia / Neil D. Woodward & Herbert Y. Meltzer -- Genetic studies in treatment resistant schizophrenia / Vincenzo De Luca ... [et al.] -- Neuroimaging of treatment resistant schizophrenia / Joao Guilherme Borgio ... [et al.] -- Duration of untreated psychosis and premorbid functioning : relationship with treatment response and therapy-resistant schizophrenia / William Bobo & Herbert Meltzer -- Disease management: multidimensional approaches to incomplete recovery in psychosis / Tim J. Lambert -- The role of clozapine in the treatment of treatment-resistant schizophrenia / Herbert Meltzer -- Augmenting clozapine response in treatment resistant schizophrenia / Gary Remington -- New therapeutic strategies for resistance to clozapine and treatment resistance schizophrenia / Juliano Santos Souza ... [et al.] -- Eletroconvulsive therapy for treatment- refractory schizophrenia / Worrawat Chanpattana -- Treatment of therapy-resistant auditory verbal hallucinations in schizophrenia patients by repetitive transcranial magnetic stimulation (rTMS) / Martin Jandl & Wolfgang P. Kaschka.
  • 2008 CRCnetBASE
    edited by Frank Robb, Garabed Antranikian, Dennis W. Grogan, Arnold J.M. Driessen.
    Introduction / Frank T. Robb ... [et al.] -- Compatible solutes of (hyper)thermophiles and their role in protein stabilization / Helena Santos ... [et al.] -- Relationships among catalytic activity, structural flexibility, and conformational stability as deduced from the analysis of mesophilic-thermophilic enzyme pairs and protein engineering studies / Reinhard Sterner and Eike Brunner -- Membranes and transport proteins of thermophilic microorganisms / Sonja Verena Albers and Arnold J.M. Driessen -- Thermophilic protein-folding systems / Frank T. Robb and Pongpan Laksanalamai -- Physical properties of membranes composed of tetraether archaeal lipids / Parkson Lee-Gau Chong -- Glycolysis in hyperthermophiles / Peter Schonheit -- Industrial relevance of thermophiles and their enzymes / Garabed Antranikian -- Denitrification pathway enzymes of thermophiles / Simon de Vries and Imke Schroder -- DNA stability and repair / Malcolm F. White and Dennis W. Grogan -- Plasmids and cloning vectors for thermophilic archaea / Kenneth M. Stedman -- Genetic analysis in extremely thermophilic bacteria : an overview / Dennis W. Grogan -- Targeted gene disruption as a tool for establishing gene function in hyperthermophilic archaea / Haruyuki Atomi and Tadayuki Imanaka -- Nanobiotechnological potential of viruses of hyperthermophilic archaea / Tamara Basta and David Prangishvili -- Master keys to DNA replication, repair, and recombination from the structural biology of enzymes from thermophiles / Li Fan ... [et al.] -- DNA replication in thermophiles / Jae-Ho Shin, Lori M. Kelman, and Zvi Kelman -- DNA-binding proteins and DNA topology / Kathleen Sandman -- Structure and evolution of the Thermus thermophilus ribosome / Steven T. Gregory and Albert E. Dalberg -- Protein phosphorylation at 80C and above / Peter J. Kennelly -- Archaeal 20S proteasome: a simple and thermostable model system for the core particle / Joshua K. Michel and Robert M. Kelly.
  • v. 1-2, 1995-96.
    contributors, J.C. Bolomey ... [et al.] ; edited by M.H. Seegenschmiedt, P. Fessenden, and C.C. Vernon ; foreword by L.W. Brady and H.-P. Heilmann.
    Status: Not Checked OutLane Catalog Record
    v. 1. Biology, physiology, physics -- v. 2 Clinical applications.
  • 2008 Karger
    volume editor, Frank E. Marino.
    The evolutionary basis of thermoregulation and exercise performance / F.E. Marino -- Comparative thermoregulation and the quest for athletic supremacy / F.E. Marino -- Thermoregulation, fatigue, and exercise modality / R. Tucker -- Neuromuscular response to exercise heat stress / S.S. Cheung -- Intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms : the "canary in the coal mine" during exercise-heat stress? / G.P. Lambert -- Effects of peripheral cooling on characteristics of local muscle / E. Drinkwater -- Cooling interventions for the protection and recovery of exercise performance from exercise-induced heat stress / R. Duffield -- Ethnicity and temperature regulation / M.I. Lambert, T. Mann, J.P. Dugas -- Exercise heat stress and metabolism / T. Mündel.
    Also available: Print – 2008
  • 2012 CRCnetBASE
    [edited by] Srikanta Sen, Lennart Nilsson.
    "Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is devoted to understanding the survival mechanisms of "thermophilic life forms" at the molecular level with an emphasis on design strategies.The review chapters presented in Thermostable Proteins span a wide range of protein thermostability research. Basic structural, thermodynamic, and kinetic principles are explained and molecular strategies for the adaptation to high temperatures are delineated. In addition, this book covers: computing and simulation methods in current and future thermostability research, especially in nonempirical situations, how rigidity theory is used to improve the thermal adaptation of mesophiles Subtilisin-like serine proteases and their significant engineering applications. The state of knowledge concerning structure function relations and the origins of their structural stability. Computational and experimental approaches for the design of proteins with increased thermal stability based on sequences or three-dimensional structures. Understanding the molecular basis of how thermostable and hyperthermostable proteins gain and maintain their stability and biological function at high temperatures remains an important scientific challenge. A more detailed knowledge of protein stability not only deepens our understanding of protein structure but also helps in obtaining insights into processes that drive protein activities folding, unfolding, and misfolding essential to biological function"--Provided by publisher.
  • 2010 Springer
    David W. McCandless.
    Early chemistry -- Early thiamine deficiency -- Thiamine deficiency in mammals -- Beriberi -- Wernicke's disease -- Central pontine myelinolysis, alcoholic cerebellar degeneration, and Marchiafava-Bignami disease -- Leigh's disease -- African seasonal ataxia -- Inherited ataxias -- Thiamine deficiency in serious illness -- World health concerns -- Future prospects -- Bontius translation -- Thiamine synonyms -- Nobel Prize acceptance speech of Dr. Christian Eijkman, 1929.
  • An online library of Thieme books. Includes Thieme eRadiology and RadCases content made available through the Medlantis database.
  • An online journal and ebook service of the Thieme Publishing Group. The ebook package is also called Thieme Clinical Collections.
  • 2012
    Tom Koch.
    Dead Germans and other philosophers: ethics as a professional or public occupation -- Something old: a brief review -- Something newer: supply-side ethics -- Lifeboat ethics: scarcity as an unnatural state -- Biopolitics, biophilosophies, and bioethics -- Principles of biomedical ethics -- Bioethics and conformal humans -- Research and genetics: "for the benefit of humankind" -- Choice, freedom, and the paternalism thing -- Complex ethics: toward an ethics of medicine.
  • 2014 CRCnetBASE
    editors, Lukasz Komsta, Monika Waksmundzka-Hajnos, Joseph Sherma.
  • 2008 CRCnetBASE
    [edited by] Monika Waksmundzka-Hajnos, Joseph Sherma, Teresa Kowalska.
  • 2004 ebrary
    Andrew Rich.
    While the number of think tanks active in American politics has more than quadrupled since the 1970s, their influence has not expanded proportionally. Instead, the known ideological proclivities of many, especially newer think tanks with their aggressive efforts to obtain high profiles, have come to undermine the credibility with which experts and expertise are generally viewed by public officials. This book explains this paradox. The analysis is based on 135 in-depth interviews with officials at think tanks and those in the policy making and funding organizations that draw upon and support their work. The book reports on results from an original survey of congressional staff and journalists and detailed case studies of the role of experts in health care and telecommunications reform debates in the 1990s and tax reduction in 2001.
  • 2009 Springer
    Tarek K.A. Hamid.
    "Thinking in Circles About Obesity brings a healthy portion of critical thinking, spiced with on-target humor and lively graphics, to the obesity debate. Systems and medical physiology scholar Tarek Hamid unites systems (non-linear) thinking and information technology to provide insights and practical strategies for managing our weight and our health. Hamid's clear insights dispel dieters' unrealistic expectations and illuminate dead-end behaviors to tap into a deeper understanding how the body works, why it works that way, and how to better manage it." --Book Jacket.
  • 2010 ScienceDirect
    edited by Enrique Cadenas and Lester Packer.
    Changing paradigms in thiology: from antioxidant defense toward redox regulation / Leopold Flohé -- Mass spectrometry-based methods for the determination of sulfur and related metabolite concentrations in cell extracts / Emmanuel Godat ... [et al.] -- Use of dimedone-based chemical probes for sulfenic acid detection: evaluation of conditions affecting probe incorporation into redox-sensitive proteins / Chananat Klomsiri ... [et al.] -- Use of dimedone-based chemical probes for sulfenic acid detection: methods to visualize and identify labeled proteins / Kimberly J. Nelson ... [et al.] -- Formation and reactions of sulfenic acid in human serum albumin / Beatriz Alvarez ... [et al.] -- Determination of GSH, GSSG, and GSNO using HPLC with electrochemical detection / Li-Peng Yap ... [et al.] -- Measurement of mixed disulfides including glutathionylated proteins / Raffaella Priora ... [et al.] -- Detection and quantification of protein disulfides in biological tissues: a fluorescence-based proteomic approach / Viviana I. Pérez ... [et al.] -- Measurement and identification of S-glutathiolated proteins / Bradford G. Hill ... [et al.] -- Proteome screens for Cys residues oxidation: the redoxome / Giovanni Chiappetta ... [et al.] -- Identification by MS/MS of disulfides produced by a functional redox transition / Pierluigi Mauri ... [et al.] -- Mass spectrometry approaches for the redox characterization of protein cysteine residues: the case of the transcription factor Pax-8 / Andrea Scaloni and Gianluca Tell -- A simple method to systematically study oxidatively modified proteins in biological samples and its applications / Byoung-Joon Song, Soo-Kyung Suh and Kwan-Hoon Moon -- Direct and indirect detection methods for the analysis of S-nitrosylated peptides and proteins / Federico Torta, Lisa Elviri and Angela Bachi -- A rapid approach for the detection, quantification, and discovery of novel sulfenic acid or S-nitrosothiol modified proteins using a biotin-switch method / Joseph R. Burgoyne and Philip Eaton -- Protein addicts of aldehydic lipid peroxidation products: identification and characterization of protein adducts using an aldehyde/keto-reactive probe in combination with mass spectrometry / Claudia S. Maier ... [et al.].
    Also available: Print – 2010
  • 2010 ScienceDirect
    edited by Enrique Cadenas and Lester Packer.
    Engineering of Fluorescent Reporters into Redox Domains to Monitor Electron Transfers / Derek Parsonage ... [et al.] -- Blot-Based Detection of Dehydroalanine-Containing Glutathione Peroxidase with the Use of Biotin-Conjugated Cysteamine / Sue Goo Rhee, Chun-Seok Cho -- Analysis of the Redox Regulation of Protein Tyrosine Phosphatase Superfamily Members Utilizing a Cysteinyl-Labeling Assay / Benoit Boivin, Nicholas K. Tonks -- Measuring the Redox State of Cellular Peroxiredoxins by Immunoblottin / Andrew G. Cox, Christine C. Winterbourn, Mark B. Hampton -- Thiol Redox Transitions by Thioredoxin and Thioredoxin-Binding Protein-2 in Cell Signaling / Eiji Yoshihara ... [et al.] -- Detection of Protein Thiols in Mitochondrial Oxidative Phosphorylation Complexes and Associated Proteins / Kelly K. Andringa, Shannon M. Bailey -- Mitochondrial Thioredoxin Reductase: Purification, Inhibitor Studies, and Role in Cell Signaling / Maria Pia Rigobello, Alberto Bindoli -- Measuring Mitochondrial Protein Thiol Redox State / Raquel Requejo ... [et al.] -- Measurement of Extracellular (Exofacial) Versus Intracellular Protein Thiols / Jolanta Skalska, Steven Bernstein, Paul Brookes -- Redox Clamp Model for Study of Extracellular Thiols and Disulfides in Redox Signaling / Young-Mi Go, Dean P. Jones -- Redox State of Human Serum Albumin in Terms of Cysteine-34 in Health and Disease / Karl Oettl, Gunther Marsche -- Methods for Studying Redox Cycling of Thioredoxin in Mediating Preconditioning-Induced Survival Genes and Proteins / Chuang C. Chiueh -- Oxidative Stress, Thiol Redox Signaling Methods in Epigenetics / Isaac K. Sundar ... [et al.] -- Characterization of Protein Targets of Mammalian Thioredoxin Reductases / Anton A. Turanov, Dolph L. Hatfield, Vadim N. Gladyshev -- Alteration of Thioredoxin Reductase 1 Levels in Elucidating Cancer Etiology / Min-Hyuk Yoo ... [et al.] -- Regulation of Apoptosis Signal-Regulating Kinase 1 in Redox Signaling / Kazumi Katagiri, Atsushi Matsuzawa, Hidenori Ichijo -- Protocols for the Detection of S-Glutathionylated and S-Nitrosylated Proteins In Situ / Scott W. Aesif, Yvonne M.W. Janssen-Heininger, Niki L. Reynaert -- Synthesis, Quantification, Characterization, and Signaling Properties of Glutathionyl Conjugates of Enals / Sanjay Srivastava ... [et al.] -- Thioredoxin and Redox Signaling in Vasculature--Studies Using Trx2 Endothelium-Specific Transgenic Mice / Wang Min ... [et al.]
    Also available: Print – 2010
  • 2008 WHO
    Litsios, Socrates.
    Understanding the history of health during the past 60 years helps us to respond to the health challenges of today. Sharing health knowledge inspired by history enriches global public health and benefits society at large. This volume offers insights into not only the Organization itself but also the political, social and economic background against which many far-reaching health decisions were made. It reflects the first five of the 'Mahler years', which saw growing support for the primary health care movement. Thirty years after Alma-Ata, that movement is once again much in evidence; primary health care is again a WHO priority, in a renewed, reinvigorated form.--Publisher's description. http://whqlibdoc.who.int/publications/2008/9789241563666_eng.pdf
    Also available: Print – 2008
  • 2014 Springer
    James M. Goldfarb, editor.
    The first IVF conceived birth in 1978 resulted in a significant growth of third party reproductive options which continue to raise ethical, legal, and psychological questions. Third party reproduction procedures can involve as many as five people: sperm donor, egg donor, gestational carrier, and intended parents. Third-Party Reproduction: A Comprehensive Guide utilizes experts in the field to address the medical, psychological, ethical and legal aspects of sperm donation, egg donation, embryo donation, and the use of gestational carriers. In addition, there are chapters on the medical and ethical aspects of posthumous reproduction, religious aspects of third party reproduction, and how to avoid pitfalls of third party reproduction. Aimed at physicians, trainees, psychologists, nurses, and social workers whose practices may include patients considering third party reproduction, the intent of this book is to provide a comprehensive and practical overview of the many aspects of third party reproduction to help all those involved to better understand them. Patients considering third party reproduction may also find value in this book.
  • 2006 Springer
    Grahame J. Kelly, Erwin Latzko.
  • Amy Werbel.
    From Benjamin Franklin to Thomas Eakins : a century of Philadelphia scientists, artists, and provocateurs -- The Agnew Clinic, the Gross Clinic, the Crucifixion, and Swimming : dissecting Eakins' paintings -- Body casts and "anatomical eyes" : Thomas Eakins, William Williams Keen, and the curriculum at the Pennsylvania Academy of the Fine Arts -- Art, pornography, freak shows, medical pictures, and the guilty pleasures of photography in nineteenth-century Philadelphia -- Scandalous exposures : the trials of Thomas Eakins, William Smith Forbes, and Oscar Wilde -- Conclusion : Thomas Eakins' family values.
  • 2009
    edited by Frederick R. Appelbaum, Stephen J. Forman, Robert S. Negrin, Karl G. Blume.
    Status: Not Checked OutLane Catalog Record
  • 2016 ClinicalKey
    Robert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard.
    Introduction to the human genome -- The human genome: gene structure and function -- Human genetic diversity: mutation and polymorphism -- Principles of clinical cytogenetics and genome analysis -- The chromosomal and genomic basis of disease: disorders of the autosomes and sex chromosomes -- Patterns of single-gene inheritance -- Complex inheritance of common multifactorial disorders -- Genetic variation in populations -- Identifying the genetic basis for human disease -- The molecular basis of genetic disease : general principles and lessons from the hemoglobinopathies -- The molecular, biochemical, and cellular basis of genetic disease -- The treatment of genetic disease -- Developmental genetics and birth defects -- Cancer genetics and genomics -- Risk assessment and genetic counseling -- Prenatal diagnosis and screening -- Application of genomics to medicine and personalized health care -- Ethical and social issues in genetics and genomics.
  • 2007
    Robert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard ; with clinical case studies updated and new cases prepared by Ada Hamosh.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    Hervé Rousseau, Jean-Philippe Verhoye, Jean-François Heautot (eds.).
  • v. 1, 1965.
    [translated from the Swedish by Victor Braxton].
    1. Surgical technique and a clinical study on 79 patients.
  • 2011 Thieme Book
    edited by Carlos Santiago Restrepo, Steven M. Zangan.
  • 2010 Thieme
    Michael Galanski ; with contributions by Sabine Dettmer [and others].
    Congenital disorders -- Disorders of the airways -- Occupational diseases -- Infections -- Idiopathic interstitial pneumonia -- Collagen diseases and vasculitis -- Immune disorders and disorders of uncertain etiology -- Bronchopulmonary neoplasms -- Disorders of the pulmonary circulatory system -- Mediastinal disorders -- Chest wall and pleura -- Chest trauma -- Sequelae of therapy.
  • Webb, Richard W.; Higgins, Charles B.
    Status: Not Checked OutLane Catalog Record
  • 2010 ClinicalKey
    Phillip M. Boiselle, MD, Associate Professor of Radiology, Harvard Medical School, Vice Chair of Quality, Safety and Performance Improvement, Director, Thoracic Imaging Section, Beth Israel Deaconess Medical Center, Boston, Massachusetts, Gerald F. Abbott, MD, Associate Professor of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Providence, Rhode Island, Associate Radiologist of Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, Theresa C. McLoud, MD, Professor of Radiology, Harvard Medical School, Associate Radiologist-in-Chief, Director of Education, Thoracic Radiologist, Massachusetts General Hospital, Boston, Massachusetts.
    "Thoracic Imaging: Case Review, by Phillip M. Boiselle, MD, Theresa C. McLoud, MD and Gerald F. Abbott, MD, tests your ability to interpret a wide range of images seen in practice. The completely revised edition of this title in the popular Case Review series features all-new cases and superb-quality accompanying images that explore the newest imaging modalities, including new treatment guidelines for lung cancer, HIV/AIDS, and pneumonia. This complete study of thoracic imaging has been organized for quick reference and easy board and recertification review. Easily find and study the most challenging topics from among approximately 200 cases-organized by difficulty - and 400 images - with questions and answers, diagnoses, commentary, references, and cross-references to Thoracic Radiology: The Requisites."--Publisher's website.
  • Soiselle, Phillip M.; Abbott, Gerald F.; McLoud, Theresa C.
    Status: Not Checked OutLane Catalog Record
  • Boiselle, Phillip M.
    Status: Not Checked OutLane Catalog Record
  • Restrepo, Carlos Santiago; Zangan, Steven M.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    Karl A. Illig, Robert W. Thompson, Julie Ann Freischlag, Dean M. Donahue, Sheldon E. Jordan, Peter I. Edgelow, editors.
    Thoracic outlet syndrome (TOS) is a condition estimated to affect as many as 80 of every 1000 patients in the US alone. While estimates vary widely based in part on lack of consensus as to the definition of the syndrome, as many as 3000 first rib resections are performed annually in the US. TOS comprises at least three separate conditions. The most common, neurogenic TOS, refers to the condition where the brachial plexus is compressed at the scalene triangle or retropectoral space, and is manifest as local and extremity pain and neurologic symptoms. Venous TOS refers to the situation where the subclavian vein is compressed by the structures making up the costoclavicular junction, and presents as acute or chronic venous thrombosis or injury or occasionally intermittent positional obstruction. Finally, arterial TOS refers to the situation where arterial injury occurs as the result of abnormal bony or ligamentous structures at the outlet, and presents as occlusion of or embolization from an abnormal artery in this area. Thoracic Outlet Syndrome brings together many experts who treat this disease and are leaders in their fields. While it can certainly be read in its entirety (and should, by all who concentrate on this condition), it is designed to be a clinical reference, residing on a shelf in a busy surgical, vascular or neurologic clinic where individual chapters can be quickly referenced. As such, the chapters are thorough, but concise and useful to answer when a specific question arises in the course of daily practice.
  • 2012 ClinicalKey
    Aliya N. Husain.
    Normal lung -- Incidental findings -- Developmental and pediatric diseases -- Pediatric tumors -- Obstructive lung (airway) diseases -- Restrictive (interstitial) lung diseases -- Granulomatous diseases (non-infectious) -- Smoking related diseases -- Miscellaneous diseases -- Diseases of vascular origin -- Pulmonary infections -- Complications of therapies -- Tumors of lung -- Nonneoplastic diseases -- Neoplastic diseases -- Normal thymus -- Nonneoplastic diseases -- Thymoma -- Other thymic tumors -- Inflammatory infectious lesions -- Cystic lesions -- Ectopic lesions -- Tumors -- Normal heart -- Congenital heart disease -- Valvular diseases -- Mycocardial diseases -- Ischemic heart disease -- Heart transplantation -- Infections -- Tumors of the heart -- Diseases of vessels.
  • 2010 ClinicalKey
    [edited by] Theresa C. McLoud, Phillip M. Boiselle.
    Thoracic radiology : imaging methods, radiographic signs, and diagnosis of chest disease / McLoud, Aquino -- Congenital abnormalities of the thorax / McLoud, Boiselle -- Pulmonary infections in the normal host / McLoud, Boiselle -- Pulmonary diseases in the immunocompromised host with or without acquired immunodeficiency syndrome / McLoud, Boiselle -- Radiography for the critical care patient / Trotman-Dickenson -- Thoracic trauma / Trotman-Dickenson, Ledbetter -- Interstitial lung disease / McLoud, Digumarthy -- The pneumoconioses / McLoud, Digumarthy -- Diseases of altered immunologic activity / McLoud, Boiselle, Trotman-Dickenson -- Chronic obstructive pulmonary disease and asthma / McLoud, Boiselle -- Pulmonary neoplasms / McLoud, Digumarthy -- The trachea / Digumarthy, Shepard -- The bronchi / Digumarthy, Shepard -- Pulmonary vascular abnormalities / Boiselle, Wittram -- The mediastinum : anatomy / Boiselle -- Mediastinal masses / Boiselle -- Diffuse mediastinal abnormalities / Boiselle -- The pleura / McLoud, Boiselle -- Interventional techniques / McLoud, Digumarthy.
    Also available: Print – 2010
  • c2010.
    [edited by] Theresa C. McLoud, Phillip M. Boiselle.
    Status: Not Checked OutLane Catalog Record
  • 2007 ClinicalKey
    Mark K. Ferguson ; illustrator, Jill Rhead.
    Incisions -- Minimally invasive approaches -- Lung -- Chest wall -- Mediastinum -- Esophagus -- Thoracic duct -- Sympathetic chain -- Diaphragm -- Major airways -- Pleura.
    Also available: Print – 2007
  • 2011 Springer
    Roberto Chiesa, Germano Melissano, Alberto Zangrillo, editors ; Joseph S. Coselli, guest editor.
    Section 1. General principles -- Section 2. Imaging -- Section 3. Anesthetic management -- Section 4. Treatment strategies and techniques -- Section 5. Specific problems -- Section 6. Advances in prosthetic management.
  • 2014 Springer
    Philippe Astoul, GianFranco Tassi, Jean-Marie Tschopp, editors.
    The incidence of pleural disease is increasing, and it is now accepted that best practice requires the incorporation of thoracoscopy into the work-up. However, surgeons cannot meet the rising demand for thoracoscopy by means of video-assisted thoracoscopic surgery (VATS), and waiting lists for endoscopic pleural procedures are consequently lengthening. Against this background, there is an increasing need for medical thoracoscopy performed by pulmonologists, which may be video assisted and has the advantage of being very cost-effective. This book is a comprehensive and up-to-date guide to thoracoscopy for pulmonologists that documents the considerable progress in endoscopic telescopes and instrumentation. Clear practical guidance is provided on technique, and diagnostic, therapeutic, and interventional applications of thoracoscopy are all carefully examined with the aid of high-quality illustrations. Although medical thoracoscopy is much less invasive than VATS and thoracotomy, complications can occur in a small number of cases; these are discussed and advice on prevention is provided. The concluding section examines the future of the field, covering developments such as 'mini' thoracoscopy, autofluorescence thoracoscopy, and flexi-rigid thoracoscopy.
  • 2006 Springer
    H. Pichlmaier, F.W. Schildberg (Hrsg.).
  • 2005 ScienceDirect
    Eric Rassin.
  • 2006 Springer
    Gwen R.J. Swennen, Filip Schutyser, Jarg-Erich Hausamen.
    From 3-D volumetric computer tomography to 3-D cephalometry / Filip Schutyser, Johan Van Cleynenbreugel -- Basic craniofacial anatomical outlines / Gwen R.J. Swennen -- 3-D cephalometric reference system / Gwen R.J. Swennen -- 3-D cephalometric hard tissue landmarks / Gwen R.J. Swennen -- 3-D cephalometric soft tissue landmarks / Gwen R.J. Swennen -- 3-D cephalometric planes / Gwen R.J. Swennen -- 3-D cephalometric analysis / Gwen R.J. Swennen -- 3-D cephalometry and craniofacial growth / Gwen R.J. Swennen -- Clinical applications / Gwen R.J. Swennen -- Future perspectives of 3-D cephalometry / Gwen R.J. Swennen, Filip Schutyse.
  • 2014 Springer
    Yulia Levakhina.
  • 2015 Springer
    Thomas Buck, Andreas Franke, Mark J. Monaghan (eds.).
    Three-dimensional echocardiography is the most recent fundamental advancement in echocardiography with a strong impact on almost all clinical and research applications of echocardiography. After a very successful 1st edition, this book presents the fully revised 2nd edition. Accounting for the marked progress of real-time 3D echocardiography since the 1st edition it covers all clinically important aspects of this fascinating new technology, including a comprehensive explanation of its basic principles, practical aspects of clinical application, new recommendations in recent guidelines, and detailed descriptions of specific uses in the broad spectrum of clinically important heart disease. The book was written by a group of well-recognized international experts in the field, who have not only been involved in scientific and clinical evolution of 3D echocardiography since its beginnings but are also intensely involved in expert training courses. As a result, the clear focus of this book is on the practical application of 3D echocardiography in daily clinical routine with tips and tricks for both beginners and experts, all accompanied by more than 150 case examples comprehensively illustrated with more than 850 images and more than 500 videos available on a DVD. In concert with an in-depth review and comprehensive update of the most recent literature on real-time 3D echocardiography, this book continues to represent an invaluable reference on 3D echocardiography for beginners and expert users.
  • 2011 Springer
    Thomas Buck, Andreas Franke, Mark J. Monaghan (editors).
  • 2011
    Sanaz Saatchi.
    Abdominal aortic aneurysms (AAA) are described by a pathological dilation of at least 150% in the abdominal aorta. Aneurysm pathogenesis is characterized by extracellular matrix (ECM) remodeling, smooth muscle cell (SMC) apoptosis, and inflammatory cell infiltration. Overall, the structural organization and integrity of the vessel wall is lost. In order to better understand the mechanism of AAA development, a novel microscopy technology, in combination with an AAA animal model, were used to visualize and quantify the microstructural and cellular changes in the vessel wall. Therefore, the goals of this work were to introduce Immunofluorescent Array Tomography (IAT), a novel three-dimensional high resolution microscopy technology, to the field of cardiovascular research, and to apply IAT to describe the vessel wall microarchitecture of a healthy aorta, as well as to investigate the spatial and temporal changes in tissue and cellular content, structure, and organization during AAA development. The purpose of the initial studies was two-fold: to develop the methods needed to enable the application of IAT to murine blood vessels and to investigate the microarchitecture of the healthy murine aorta. The anterior and posterior regions of the infrarenal aorta of 8 to 10 week old C57BL6 mice were evaluated. Staining and custom image analysis methods were developed. Antibody selection, primary antibody concentration, co-staining with multiple primary antibodies, and the multi-cycle staining design were optimized to produce positive and specific staining of elastin, smooth muscle cell actin (SMCA), and collagen type I. Algorithms were developed and applied to the healthy murine aorta to quantify volume fractions (VF) of medial elastin (27.5 ± 0.99%), SMCA (18.4 ± 0.67%), and nuclei (6.1 ± 0.14%), as well as adventitial collagen type I (22.3 ± 1.7%). Elastin thickness (1.6 ± 0.35 [Mu]m), spacing between elastin lamellae (3.5 ± 0.13 [Mu]m), elastin fragmentation (4.2 x 10-3 ± 1.6 x 10-4 # of objects/elastin area ([Mu]m)), media wall thickness (20.4 ± 3.1 [Mu]m), nuclei aspect ratio (3.2 ± 0.21 [Mu]m), and nuclei amount (17.3 ± 0.69 nuclei) were also quantified. The 3D microstructure and cellular morphology of the anterior and posterior infrarenal murine aorta were qualitatively and quantitatively described using IAT. IAT was then used to investigate the spatial and temporal remodeling of vessel wall microarchitecture and cellular morphology during AAA development in the murine elastase perfusion model. Infrarenal aortas of C57BL6 mice (N=20) were evaluated at 0, 7 and 28 days after elastase or heat-inactivated elastase perfusion. Custom algorithms quantified VFs of elastin, SMCA, and adventitial collagen type I, as well as elastin thickness, elastin fragmentation, media thickness, and nuclei amount. 3D renderings depicted elastin and collagen type I degradation, and dynamic changes in SMC phenotype, morphology, and amount. Elastin degradation was described by a 37.5% (p < 0.01) loss in VF, 48.9% decrease in thickness, and a 449.7% (p < 0.001) increase in fragmentation over 28 days. SMCA VF decreased 78.3% (p < 0.001) from Day 0 to Day 7, and increased 139.7% (p < 0.05) from Day 7 to Day 28. Media thickness increased 61.1% and medial nuclei amount increased 159.1% (p < 0.01) over 28 days. Adventitial collagen type I VF decreased 64.1% (p < 0.001) over 28 days. IAT and custom image analysis algorithms have enabled robust quantification of vessel wall content, microstructure, and organization to help elucidate the unique dynamics of major tissue constituent remodeling during AAA development. In conclusion, the methodologies needed to enable the application of IAT to cardiovascular research have been developed, the healthy murine vessel wall microarchitecture has been qualitatively and quantitatively described, and the unique dynamics of vascular remodeling during aneurysm development have been investigated.
  • 2006
    by Shannon Moffett.
    Status: Not Checked OutLane Catalog Record
    Postconception -- Touching the brain -- Embryonic period -- Watching the brain -- Fetal period -- Mining the brain -- Childhood -- The dreaming brain -- Adolescence -- Multiple minds -- Adulthood -- Mind and magic -- Old age -- Open mind -- Death -- Mind and body.
  • 2009 Springer
    Michael E. Maragoudakis, Nikos E. Tsopanoglou, editors.
  • 2013 Springer
    Juan V. Llau, editor.
    1. Thromboembolism in Orthopedic Surgery: Scope of the Problem / Bengt I. Eriksson and Ola E. Dahl -- 2. Incidence of Venous Thromboembolism in Orthopedic Surgery / Ajay K. Kakkar and Sophie K. Rushton-Smith -- 3. Specific Risk Factors for Venous Thromboembolism in Orthopedics / Lasse J. Lapidus -- 4. Diagnosis and Treatment of Deep Vein Thrombosis and Pulmonary Embolism After Major Joint Surgery / Manuel Monreal and Juan I. Arcelus -- 5. Drugs for Thromboprophylaxis: Unfractionated Heparin, Low Molecular Weight Heparin, Warfarin, and Fondaparinux / José Aguirre and Alain Borgeat -- 6. New Drugs for Thromboprophylaxis: Apixaban, Dabigatran, Rivaroxaban / Raquel Ferrandis -- 7. Effectiveness of Mechanical Devices in Orthopedic Surgery / David J. Warwick -- 8. Anesthetic Implications of Thromboprophylaxis / Sibylle A. Kozek-Langenecker -- 9. Thromboprophylaxis in High-Risk Orthopedic Surgery: Total Hip and Knee Arthroplasty and Hip Fracture / Juan V. Llau and Raquel Ferrandis -- 10. Thromboprophylaxis in Day Surgery: Knee Arthroscopy and Ligamentoplasty (Ligament Reconstruction) / James E. Muntz, Steven E. Flores, and Walter R. Lowe -- 11. Thromboprophylaxis in Special Patients: Multiple Trauma, Head Trauma, and Spine Surgery / Maria J. Colomina, Lidia Mora, and Esther Ciércoles -- 12. Management of Antiaggregated and Anticoagulated Patients Scheduled for Orthopedic Surgery / Raquel Ferrandis and Juan V. Llau.
  • 2015 Springer
    Carlos Jerjes-Sánchez.
    1. Mechanisms of thrombosis -- 2. Pharmacokinetics and pharmacodynamics of fibrinolytic agents -- 3. Thrombolytic therapy: evidence-based results from multicenter control trials -- 4.Patients for thrombolysis -- 5. Anticoagulation as adjunctive treatment and one-hour alteplase infusion -- 6. Current guidelines and recommendations for thrombolysis use in pulmonary embolism -- 7. Thrombolysis in pulmonary embolism -- 8. Thrombolysis in special situations -- Index.
  • 2005 Springer
    edited by Patrick D. Lyden.
  • 2014 Springer
    Thomas Boehm, Yousuke Takahama, editors.
    The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
  • 2007 Springer
    Kyriakos Anastasiadis, Chandi Ratnatunga, eds.
  • 2008 Springer
    Corrado Lavini ... [et al.], eds.
  • 2009 Springer
    Giorgio Iervasi, Alessandro Pingitore, editors ; forewords by Paul W. Ladenson, Attilio Maseri.
  • 2012 Springer
    Glenn D. Braunstein, editor.
    The American Cancer Society recently estimated that about 45,000 new cases of thyroid cancer will be diagnosed in the United States, with three-quarters occurring in women. The overall 5-year survival rate is about 97%, making it one of the least lethal cancers. We are experiencing an epidemic of well-differentiated thyroid cancer, in part due to the widespread use of imaging modalities that detect thyroid nodules and microcarcinomas. Concurrently, there have been a number of recent advances in surgical treatment, as well as diagnostic modalities that allow us to detect small amounts of residual local and metastatic disease. Additionally, a reexamination of past treatment regimens has led to new recommendations regarding the use of radioactive iodine, and to new therapeutic options, such as targeted therapy which have supplanted the use of more toxic chemotherapy for metastatic cancer. Multiple academic organizations have developed consensus guidelines for the management of thyroid cancer, occasionally with conflicting recommendations. In Thyroid Cancer, a renowned group of authors presents a broad overview of the pathology, pathophysiology, diagnosis, and management of thyroid cancer, with an emphasis on recent evidence-based information. State-of-the-art and a significant contribution to the literature, Thyroid Cancer is an invaluable reference for endocrinologists, oncologists, nuclear medicine physicians, radiation oncologists, primary care physicians, and surgeons who deal with head and neck cancer.
  • 2006 Springer
    edited by Leonard Wartofsky, Douglas Van Nostrand ; forewords by E. Chester Ridgway and Ernest L. Mazzaferri.
    Also available: Print – 2006
  • 2011 CRCnetBASE
    editors, Angelo Carpi, Jeffrey I. Mechanick.
    "Thyroid cancer evaluation and treatment has enjoyed very little evolution in comparison with other disease management strategies. The standard treatment algorithms for thyroid cancer have varied only in response to major, though infrequent, biotechnological innovations. These resultant algorithm node insertions produced paradigm changes, but there has been little to advance the care of the patient with advanced thyroid cancer--until very recently. Perhaps the reasons for a relative lack of interest and scientific progress are the overwhelming likelihood of benignity among thyroid nodules, the overwhelmingly favorable clinical outcome even if a patient has thyroid cancer, and the overwhelming long time required for clinical follow-up of these cancer patients. Unfortunately, the problem now is that we may be overmanaging low-risk patients, and we have not achieved the clinical responses we would have liked with high-risk patients"--Provided by publisher.
  • 2016 Springer
    David S. Cooper, Cosimo Durante, editors.
    Part 1 Low Risk Differentiated Thyroid Cancer: Preoperative diagnosis -- Chapter 1 A patient with a single thyroid nodule suspicious for follicular neoplasm according to the Bethesda System for Reporting Thyroid Cytopathology: molecular evaluation -- Part 2 Low Risk Differentiated Thyroid Cancer: Initial management: extent of surgery and use of radioactive iodine therapy -- Chapter 2 A case of a small (1 to 2 cm) papillary thyroid cancer in a young patient: lobectomy vs. total thyroidectomy -- Chapter 3 The decision-making process for prophylactic central neck dissection in a patient presenting with nodular thyroid disease suspicious for malignancy on cytology assessment: role of preoperative ultrasound and molecular marker testing -- Chapter 4 Incidentally discovered micropapillary thyroid cancer -- Chapter 5 Completion thyroidectomy in a patient with low risk papillary cancer -- Chapter 6 A case of multifocal micropapillary thyroid cancer -- Chapter 7 A papillary thyroid cancer with minimal extra-thyroidal extension -- Chapter 8 A case of a papillary thyroid cancer with lymph node metastases found on prophylactic central neck dissection (subclinical disease, micrometastases) -- Chapter 9 Papillary thyroid cancer with central neck lymph node metastases -- Chapter 10 A patient with a large minimally invasive follicular thyroid cancer -- Chapter 11 A young patient with intrathyroidal papillary thyroid cancer and family history of differentiated thyroid cancer -- Chapter 12 A child with papillary thyroid cancer and locally advanced disease but no distant metastasis -- Part 3 Low Risk Differentiated Thyroid Cancer: Postoperative follow-up -- Chapter 13 A patient with papillary thyroid cancer and biochemical evidence of disease at the 1-yr follow-up visit -- Chapter 14 Low but detectable suppressed thyroglobulin levels in thyroid cancer patients? follow-up: How to interpret and manage these cases? -- Chapter 15 A young patient with papillary thyroid cancer and biochemical evidence of disease at the follow-up visits and increasing serum Tg values at the follow up assessments -- Chapter 16 A young patient with recurrent lymph node involvement: imaging, cytology, Tg washout -- Part 4 Low Risk Differentiated Thyroid Cancer: Special issues -- Chapter 17 Papillary thyroid carcinoma diagnosed during pregnancy -- Chapter 18 Risks of Thyroid Hormone Suppression for Differentiated Thyroid Cancer in the Elderly -- Chapter 19 A patient in whom one pathologist says she has cancer and another says that the lesion is benign -- Chapter 20: A case with postsurgical hypoparathyroidism -- Chapter 21 A case with postsurgical recurrent laryngeal nerve damage and nerve monitoring -- Part 5 High Risk Differentiated Thyroid Cancer: The need for additional therapy -- Chapter 22 A case of papillary thyroid cancer without aggressive histological features with nodal metastases detected during follow-up in a younger patient -- Chapter 23 A case of papillary thyroid cancer without aggressive histological features with nodal metastases in an older patient -- Chapter 24 A patient with a large Hũrthle cell carcinoma of the thyroid and nodal metastases -- Chapter 25 A case of a large, invasive PTC with gross residual disease (pT4) after surgery -- Part 6 High Risk Differentiated Thyroid Cancer: The use of radioiodine -- Chapter 26 A patient with papillary carcinoma of the thyroid with elevated serum thyroglobulin but negative imaging studies -- Chapter 27 A young child with papillary thyroid cancer and metastatic pulmonary disease: whole issue of radioactive iodine therapy in children -- Chapter 28 A patient with bone metastases from follicular carcinoma of the thyroid -- Chapter 29 Radioiodine Therapy in Lactating Women with High Risk Differentiated Thyroid Cancer -- Part 7 High Risk Differentiated Thyroid Cancer: The use of local treatments and novel systemic chemotherapies -- Chapter 30 A case of a patient with radioactive iodine refractory differentiated thyroid cancer with progressive neck disease (latero-cervical lymph nodes) and stable, small lung metastases -- Chapter 31 A case of an elderly patient with advanced disease and non radioiodine avid metastases -- Chapter 32 Radioactive iodine refractory differentiated thyroid cancer with multiple organ progressive disease -- Chapter 33 Radioactive iodine refractory differentiated thyroid cancer and lung lesions causing bleeding -- Chapter 34 A patient with follicular thyroid cancer and a painful bone metastasis at risk for pathologic fracture -- Chapter 35 Differentiated thyroid cancer and brain -- Part 8 High Risk Differentiated Thyroid Cancer: Novel chemotherapy and toxicity -- Chapter 36 Radioactive iodine refractory, advanced differentiated thyroid cancer receiving tyrosine kinase inhibitor treatment: checking for drug-drug interactions -- Chapter 37 A patient with advanced differentiated radioactive iodine-refractory thyroid cancer receiving tyrosine kinase inhibitor treatment: managing hypertension, QTc prolongation, dermatologic and gastrointestinal adverse events -- Part 9 Medullary Thyroid Cancer: Postoperative management -- Chapter 38 Management of post-operative hypercalcitoninemia in medullary thyroid cancer -- Chapter 39 A patient with metastatic medullary thyroid carcinoma (MTC) and tumor-related diarrhea -- Chapter 40 Clinical management of a patient with a locally recurrent medullary thyroid cancer and asymptomatic slowly progressing distant metastases -- Chapter 41 A patient with an advanced medullary thyroid cancer and progressive, symptomatic distant metastases: when to start systemic therapy -- Chapter 42 Medical Treatment Decision-Making for Advanced, Progressive Medullary Thyroid Cancer -- Part 10 Medullary Thyroid Cancer: Special issues -- Chapter 43 Screening leading to diagnosis of C cell hyperplasia -- Chapter 44 Increased basal calcitonin in nodular goiter: Is it micromedullary thyroid cancer? -- Chapter 45 Timing and extent of surgery for a pediatric patient with hereditary MTC and positive screening for the S891A RET mutation -- Part 11 Thyroid lymphoma -- Chapter 46 Thyroid Lymphoma: Differential Diagnosis -- Part 12 Anaplastic thyroid cancer -- Chapter 47 Anaplastic Thyroid Cancer: Surgery or Not in Locally Advanced Disease.
  • 2007 Springer
    I. Ross McDougall.
  • 2005 Springer
    H.-J. Biersack, F. Grünwald, eds.
  • 2008
    Sudha R. Kini.
    Status: Not Checked OutLane Catalog Record
    Introduction / J. Martin Miller and Max Wisgerhof -- Techniques of fine-needle aspiration biopsy / J. Martin Miller and Max Wisgerhof -- Cytopreparatory techniques -- Specimen adequacy and asessment, reporting scheme -- Concepts basic to thyroid cytopathology and guidelines for evaluating thyroid fine-needle aspirates -- Nodular goiter -- Follicular adenoma and follicular carcinoma -- Hürthle cell lesions -- Papillary carcinoma -- Poorly differentiated "insular" carcinoma -- Anaplastic carcinoma -- Medullary carcinoma -- Thyroiditis -- Malignant lymphoma -- Thyroid carcinomas metastatic to other body sites -- Metastatic malignancy to the thyroid -- Cysts and cystic lesions of the thyroid -- Spindle cells in thyroid aspirates -- Miscellaneous lesions of the thyroid -- Infarction of thyroid neoplasms following fine-needle biopsy -- Lesions of the parathyroid glands -- Ancillary diagnostic techniques / Osama Alassi ... [et al.] -- Application of needle biopsy data to management decisions / J. Martin Miller.
  • 2010 Springer
    Douglas P. Clark, William C. Faquin.
  • 2005 Springer
    Emanuel O. Brams ; foreword by Steven N. Levine.
    Foreword vii -- Preface -- Acknowledgments -- Part 1. Physiology, testing, and common thyroid disorders -- Introduction -- Thyroid testing and imaging -- Graves' disease -- Other causes of hyperthyroidism -- Thyroid ophthalmopathy -- Hypothyroidism -- Subclinical thyroid disease -- Hashimoto's thyroiditis -- Thyroid disease in pregnancy and post partum -- Thyroid disease in children and adolescents -- Thyroid nodules and cancer -- Management of thyroid cancer patients -- Part 2. Challenging thyroid disorders and current controversies -- Challenging cases of hyperthyroidism -- Treatment of Graves' disease: a personal perspective -- Iatrogenic hyperthyroidism -- Final thoughts -- Index.
  • 2011 Springer
    Ernst Nyström, Gertrud E. B. Berg, Svante K.G. Jansson, Ove Tørring, Stig V. Valdemarsson.
  • 2015 Springer
    Gianni Bona, Filippo De Luca, Alice Monzani, editors.
    This book covers the entire spectrum of thyroid diseases in childhood, focusing on the recent advances that have been achieved, from progress in basic science research through to novel or improved approaches to diagnosis and treatment. Introductory chapters discuss thyroid embryogenesis and the role of thyroid hormones in fetal development. The two contrasting forms of thyroid dysfunction, hypo- and hyperthyroidism, are then considered in depth, with particular attention to the molecular causes of congenital hypothyroidism. Among the other topics addressed are autoimmune thyroiditis, thyroid nodules, and pediatric neoplasms. The book concludes with an overview of promising therapeutic approaches, such as stem cell therapy. Each topic is treated by an eminent expert in the field, ensuring consistently high quality. Thyroid Diseases in Childhood will be an important source of information for endocrinologists, pediatricians, oncologists, and gynecologists, as well as other professionals interested in this topic.
  • 2016 Springer
    Syed Khalid Imam, Shamim I. Ahmad, editors.
    This comprehensive book provides core understanding and clinical knowledge to all those involved in managing thyroid disorders. The authors examine the basic thyroid glandular functions which are essential in understanding the pathophysiology and clinical aspects of this disease. The chapters present recent trends, technologies and advancements in the management of thyroid diseases to help readers keep abreast of modern thyroid disease management. Some special and important issues such as pregnancy and thyroid diseases, psychiatric disorders and thyroid, and subclinical thyroid dysfunctions are also included. Thyroid Disorders - Basic Science and Clinical Practice is aimed at physicians, endocrinologists, endocrine surgeons and general surgeons with special interest in thyroid management, as well as dieticians, researchers and medical students at all levels.
  • 2008 Springer
    edited by Warren R. Heymann.
    Anatomy and Embryology of the Thyroid Gland / Gabriel Wong and Scott Schaffer -- Hormones / Airani Sathananthan, Kimberly A. Placzkowski and John C. Morris -- Classification and Epidemiology of Thyroid Disease / Ghada Haddad and Steven Kaufman -- Laboratory Diagnosis of Thyroid Disease / Reagan Schiefer and Vahab Fatourechi -- Thyroglossal Duct Cysts / Lisa M. Reid -- Thyroid Cancer and the Skin / Robert A. Somer and Nati Lerman -- Chromosomes, Genes, and the Thyroid Gland / Analisa V. Halpern and Rhonda E. Schnur -- Cutaneous Manifestations of Hyperthyroidism / Clara-Dina Cokonis, Carrie W. Cobb, Warren R. Heymann and Chad M. Hivnor -- Cutaneous Manifestations of Hypothyroidism / Sandra A. Kopp, Pascal G. Ferzli, Chad M. Hivnor and Warren R. Heymann -- Pretibial Myxedema (Thyroid Dermopathy) / Vahab Fatourechi -- Alopecia and Thyroid Disease / Michelle Babb-Tarbox and Wilma F. Bergfeld -- Chronic Idiopathic Urticaria and Thyroid Disease / Jeffrey S Rumbyrt and Alan L Schocket -- Dermatologic Disorders Associated with Thyroid Disease / Joslyn Sciacca Kirby and William D. James -- Potential Therapeutic Uses of Thyroid Hormone / Joshua D. Safer and Michael F. Holick.
  • 2015 Springer
    edited by Raymond S. Douglas, Allison N. McCoy, Shivani Gupta.
    This book offers ophthalmologists and medical practitioners a concise, data-driven review of the information that is most relevant in guiding the diagnosis and management of thyroid eye disease (TED). Particular attention is devoted to research and clinical trials that have advanced the field in recent years. Progress in our understanding of the pathogenesis of TED is described, and the heterogeneous natural history of TED is discussed to facilitate preemptive interventions. Advances in diagnostic evaluation, including autoantibody assessment, are reviewed with regard to their clinical utility. The diagnostic features of euthyroid TED are also carefully covered since these patients often represent a diagnostic dilemma. All relevant aspects of treatment are addressed including the role of radioactive iodine, long-term medical therapy, and surgical thyroidectomy. The impact of these treatment modalities on eye disease are discussed. Management of active TED is reviewed according to the severity of disease and in the light of recent findings and the introduction of novel agents. The discussion encompasses the role of steroids and other agents, the use of novel biologics, the medical and surgical treatment of optic neuropathy, and minimally invasive, customized reconstructive surgery. Numerous supporting images are included, and helpful checklists will aid the practitioner in treatment decision making.
  • 2010 Springer
    edited by Gregory A. Brent.
    Thyroid Hormone Metabolism / Stephen A. Huang and Luciana A. de Castro Neves -- Genetic Influences on Thyroid Function Tests / Wendy M. van der Deure, Marco Medici, Robin P. Peeters and Theo J. Visser -- Influence of Iodine Deficiency and Excess on Thyroid Function Tests / Maria Andersson and Michael B. Zimmermann -- Regulation of Thyroid Hormone Production and Measurement of Thyrotropin / Jerome M. Hershman -- Measurements of Thyroxine and Triiodothyronine / Jim R. Stockigt -- Thyroid Autoantibody Measurement / R. A. Ajjan and A. P. Weetman -- Thyroglobulin Measurement / Carole Spencer and Ivana Petrovic -- Thyroid Function Testing in Ambulatory Practice / Angela M. Leung and Alan P. Farwell -- Assessing Thyroid Function in Infants and Children / Alicia G. Marks and Stephen H. LaFranchi -- Assessing Thyroid Function in Hospitalized Patients / Jonathan S. LoPresti and Komal S. Patil -- Assessing Thyroid Function in Pregnancy / John H. Lazarus, Offie P. Soldin and Carol Evans -- Assessing Thyroid Function in the Elderly / Mary H. Samuels -- Influence of Drugs on Thyroid Function Tests / Sonia Ananthakrishnan and Elizabeth N. Pearce.
  • 2007 Karger
    volume editors, Guy Van Vliet, Michel Polak.
    Murine models for the study of thyroid gland development / M. De Felice, R. Di Lauro -- Familial forms of thyroid dysgenesis / M. Castanet, M. Polak, J. Léger -- Possible non-Mendelian mechanisms of thyroid dysgenesis / J. Deladoëy, G. Vassart, G. Van Vliet -- Thyroid imaging in children / C. Garel, J. Léger -- Clinical and biological consequences of iodine deficiency during pregnancy / D. Glinoer -- Ontogenesis of thyroid function and interactions with maternal function / M.J. Obregon ... [et al.] -- New phenotypes in thyroid dyshormonogenesis: hypothyroidism due to DUOX2 mutations / J.C. Moreno, T.J. Visser -- Thyroid hormone transporter defects / A. Grüters -- Novel biological and clinical aspects of thyroid hormone metabolism / A.M. Dumitrescu, S. Refetoff -- Papillary and follicular thyroid cancers in children / V. Vasko ... [et al.] -- Hereditary medullary thyroid carcinoma: how molecular genetics made multiple endocrine neoplasia type 2 a paediatric disease / G. Szinnai, S. Sarnacki, M. Polak.
  • 2005 ScienceDirect
    editor, Bryan Haugen.
    Gene rearrangements in thryoid cancer -- Molecular markers of thyroid nodules -- Ultrasound in the diagnosis and management of thyroid cancer -- Controversies in the use of radioiodine for remnant ablation and therapy of thyroid carcinoma -- Thyroglobulin measurements in thryoid cancer evaluation and surveillance -- The role of fluoro-deoxy glucose (FDG) positron emission tomorgraphy (PET) in the management of differentiated thyroid cancer -- Preclinical studies of chemotherapy for undifferentiated thyroid carcinoma -- Medullary thyroid carcinoma -- Thyroid neoplasms in children and adolescents.
    Also available: Print – 2005
  • 2008 Springer
    [edited by] H. Jack Baskin, Daniel S. Duick, Robert A. Levine ; foreword by Leonard Wartofsky.
  • 2013 Springer
    H. Jack Baskin, Sr., Daniel S. Duick, Robert A. Levine, editors.
    History of Thyroid Ultrasound / Robert A. Levine -- Thyroid Ultrasound Physics / Robert A. Levine -- Doppler Ultrasound of the Neck / Robert A. Levine -- Normal Neck Anatomy and Method of Performing Ultrasound Examination / Dara R. Treadwell -- Pediatric Ultrasound of the Neck / Henry J. Baskin Jr -- Ultrasound of Diffuse Thyroid Enlargement: Thyroiditis / Mark A. Lupo and Robert A. Levine -- Ultrasound of Nodular Thyroid Enlargement / Susan J. Mandel and Jill E. Langer -- Ultrasound and Mapping of Neck Lymph Nodes / Gregory Randolph, Barry Sacks and H. Jack Baskin Sr -- Ultrasonography of the Parathyroid Glands / Dev Abraham -- Surgical Trends in Treatment of Thyroid Nodules, Thyroid Cancer, and Parathyroid Disease / Haengrang Ryu, Rachel Harris and Nancy D. Perrier -- Ultrasound of Salivary Glands and the Non-endocrine Neck / Robert A. Sofferman -- Ultrasound-Guided Fine-Needle: Aspiration of Thyroid Nodules / Daniel S. Duick -- Laser and Radiofrequency Ablation Procedures / Roberto Valcavi, Giorgio Stecconi Bortolani and Fabrizio Riganti -- Percutaneous Ethanol Injection (PEI) in the Treatment of Thyroid Cysts, Nodules, and Other Neck Lesions / Andrea Frasoldati and Roberto Valcavi -- Ultrasound-Guided FNA and Molecular Markers for Optimization of Thyroid Nodule Management / Daniel S. Duick -- Ultrasound Elastography of the Thyroid / Robert A. Levine -- Authoring Quality Ultrasound Reports / J. Woody Sistrunk and H. Jack Baskin Sr.
  • 2014 Karger
    volume editors, S. Uchiyama, P. Amarenco, K. Minematsu, K.S.L. Wong.
    History of transient ischemic attack definition / Mohr, J.P. -- The concept of acute cerebrovascular syndrome / Uchiyama, S. -- Transient ischemic attack as a medical emergency / Okada, Y. -- TIA clinic : a major advance in management of transient ischemic attacks / Lavalle, P.; Amarenco, P. -- Risk scores for transient ischemic attack / Wolf, M.E.; Held, V.E.; Hennerici, M.G. -- Epidemiology of transient ischemic attack / Kokubo, Y. -- Symptoms of transient ischemic attack / Kim, J.S. -- Guidelines for management of patients with transient ischemic attack / Uehara, T.; Minematsu, K. -- Radiological examinations of transient ischemic attack / Tung, C.E.; Olivot, J.M.; Albers, G.W. -- Neurosonological examinations of transient ischemic attack / Sharma, V.K.; Wong, K.S.L. -- Stroke subtypes and interventional studies for transient ischemic attack / Lavalle, P.; Amarenco, P. -- Antithrombotic therapy in transient ischemic attack patients / Held, V.E.; Wolf, M.E.; Hennerici, M.G.
  • 2013 ScienceDirect
    Porter, Stuart B.; Tidy, Noël M.
    The responsibilities of being a physiotherapist / Ralph Hammond and Ceri Sedgley -- Inter-professional education and team working / Alison Chambers .̤ [et al.] -- Clinical leadership and professionalism / Alison Chambers -- Pharmacology for physiotherapists / Nicholas Southorn -- Reflection / Linda Hollingworth, Sarah Dunbar, and Lindsey Dugdill -- Respiratory diseases / Stephanie Enright and Fiona Schreuder -- Adult spontaneous and conventional mechanical ventilation / Sue Pieri-Davies, Helen Carruthers, and Melanie Reardon -- Cardiac and pulmonary rehabilitation / Sushma Sanghivi -- Physiotherapy in cardiothoracic surgery / Anne Dyson and Kelly Youd -- Changing relationships for changing health / Sally French and John Swain -- Musculoskeletal assessment / Lynne Gaskell -- Tissue inflammation and repair / Janette Grey -- Exercise in rehabilitation / Duncan Mason -- Muscle imbalance / Alan Chamberlain, Wendy Munro and Alex Rickard -- Biomechanics / Jim Richards, Renuka Erande and Ambreen Chohan -- Sports management / Hilary Pape -- Pain / Lester Jones, Lorimer Moseley, Catherine Carus -- Acupuncture / Andrew Bannan -- Electrotherapy / Tim Watson -- Physiotherapy for people with amputation / Carolyn Hale -- Massage / Joan watt -- An introduction to fractures / Annie Karim -- Upper and lower limb joint arthroplasty / Ann Price -- Older people / Bhanu Ramaswamy and Paula McCandless -- Neurodynamics / Monika Lohkamp, Katie Small, and Lee Herrington -- Neurological physiotherapy / Christine Smith, Anita Watson, and Louise Connell -- Physiotherapy in women's health / Gill Brook ... [et al.].
  • 2013 ClinicalKey
    [edited by] Carl A. Burtis, Edward R. Ashwood, David E. Bruns.
    "As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics."--Publisher's website.
  • 2006
    [edited by] Carl A. Burtis, Edward R. Ashwood, David E. Bruns.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    [edited by] Lorenza Gonzalez-Mariscal.
    Evolution of the transporting epithelium phenotype / Marcelino Cereijido ... [et al.] -- Occludin, a constituent of tight junctions / Yan-Hua Chen, Daniel A. Goodenough and Qun Lu -- Tight junction channels / James Melvin Anderson and Christina M. Van Itallie -- JAM family proteins: tight junction proteins that belong to the immunoglobulin superfamily / Susumu Hirabayashi and Yutaka Hata -- Cingulin, a cytoskeleton-associated protein of the tight junction / Laurent Guillemot and Sandra Citi -- ZO proteins and tight junction assembly / Alan S. Fanning -- TJ proteins that make round trips to the nucleus / Esther Lopez-Bayghen ... [et al.] -- Tight junctions and the regulation of epithelial -- Cell proliferation and gene expression / Emma Kavanagh ... [et al.] -- Tight junction proteins and cancer / Isabel J. Latorre, Kristopher K. Frese and Ronald T. Javier -- Regulation of paracellular transport across tight junctions by the actin cytoskeleton / Matthias Bruewer and Asma Nusrat -- Regulation of tight junctions' functional integrity: role of a urinary factor, lipids, and ouabain / Liora Shoshani ... [et al.] -- Tight junctions during development / Bhavwanti Sheth ... [et al.] -- Tight junctions and the blood-brain barrier / Hartwig Wolburg, Andrea Lippoldt, and Klaus Ebnet -- Tight junctions in CNS myelin / Jeff M. Bronstein and Seema Tiwari-Woodruff -- Tight junction modulation and its relationship to drug delivery / Noha N. Salama, Natalie D. Eddington and Alessio Fasano.
  • 2013 Springer
    Tracey A. Martin, Wen G. Jiang, editors.
    There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells.
  • 2013 Springer Protocols
    edited Tin-Lap Lee, Alfred Chun Shui Luk.
    A Brief Introduction to Tiling Microarrays: Principles, Concepts, and Applications -- Design of Tiling Arrays and their Application to Bacterial Transcriptome Analysis -- Transcript Profiling in Arabidopsis with Genome Tiling Microarrays -- Genome-wide Analysis of Transcription Factor Binding Sites in Skeletal Muscle Cells using ChIP-seq -- Analysis of Allele-Specific Gene Expression Using a Target-Oriented Tiling Microarray Assay -- Detection of Epigenetic Alterations Using Tiling Arrays -- Investigating Gene Promoter Methylation in a Mouse Model of Status Epilepticus -- Integrative Analysis of ChIP-chip and ChIP-seq Dataset -- HAT: A Novel Statistical Approach to Discover Functional Regions in the Genome -- Inference of Alternative Splicing from Tiling Array Data -- Analysis of in vivo Occupancy of Aebp1, a Transcription Factor, using High Resolution Tiling Array -- Application of the Simple and Efficient MPeak Modeling in Binding Peak Identification in CHIP-CHIP Studies -- Evaluation of MeDIP-chip in the Context of Whole Genome Bisulphite Sequencing (WGBS-seq) in Arabidopsis -- Mapping Genomic Features of Tiling Microarray Data by TileMapper.
  • 2012
    Philip G. Zimbardo, Richard M. Sword, Rosemary K.M. Sword.
    Status: Not Checked OutLane Catalog Record
    PTSD and time perspective therapy. How PTSD sufferers get stuck in time -- A new psychology of time -- Time perspective therapy -- The stories. War veterans, PTSD, and time perspective therapy -- Everyday trauma, PTSD, and time perspective therapy -- Women, PTSD, and time perspective therapy -- Appendix A: How TPT compares with other approaches -- Appendix B: Clinical trial: TPT pilot study research data -- Appendix C: Client psychological test scores.
  • 2012 CRCnetBASE
    Tohru Ozaki.
    "Recent advances in brain science measurement technology have given researchers access to very large-scale time series data such as EEG/MEG data (20 to 100 dimensional) and fMRI (140,000 dimensional) data. To analyze such massive data, efficient computational and statistical methods are required. Time Series Modeling of Neuroscience Data shows how to efficiently analyze neuroscience data by the Wiener-Kalman-Akaike approach, in which dynamic models of all kinds, such as linear/nonlinear differential equation models and time series models, are used for whitening the temporally dependent time series in the framework of linear/nonlinear state space models. Using as little mathematics as possible, this book explores some of its basic concepts and their derivatives as useful tools for time series analysis. Unique features include: statistical identification method of highly nonlinear dynamical systems such as the Hodgkin-Huxley model, Lorenz chaos model, Zetterberg Model, and more Methods and applications for Dynamic Causality Analysis developed by Wiener, Granger, and Akaike state space modeling method for dynamicization of solutions for the Inverse Problems heteroscedastic state space modeling method for dynamic non-stationary signal decomposition for applications to signal detection problems in EEG data analysis An innovation-based method for the characterization of nonlinear and/or non-Gaussian time series An innovation-based method for spatial time series modeling for fMRI data analysis The main point of interest in this book is to show that the same data can be treated using both a dynamical system and time series approach so that the neural and physiological information can be extracted more efficiently. Of course, time series modeling is valid not only in neuroscience data analysis but also in many other sciences and engineering fields where the statistical inference from the observed time series data plays an important role"--Provided by publisher.
  • 2014
    recommendations from the Robert Wood Johnson Foundation Commission to Build a Healthier America.
    As we consider ways to improve our nation's overall health, we must consider options that will improve opportunities for all, with special emphasis on lifting up low-income children and those who are in danger of being left behind. A stronger, healthier America hinges on our ability to build a sustainable foundation for generations to come.
  • 2012 Springer
    Jos J. Eggermont ... [et al.], editors.
    Historical Reflections on Current Issues in Tinnitus / Jos J. Eggermont and Fan-Gang Zeng -- Behavioral Tests for Tinnitus in Animals / Henry E. Heffner and Rickye S. Heffner -- Molecular Mechanism of Tinnitus / Marlies Knipper, Marcus Müller and Ulrike Zimmermann -- The Cochlea and the Auditory Nerve as a Primary Source of Tinnitus / Régis Nouvian, Michel Eybalin and Jean-Luc Puel -- Dorsal Cochlear Nucleus: Somatosensory-Auditory Interactions in Tinnitus / Susanne Dehmel, Seth D. Koehler and Susan E. Shore -- The Inferior Colliculus: Involvement in Hyperactivity and Tinnitus / Donald Robertson and Wilhelmina Mulders -- Cortex: Way Station or Locus of the Tinnitus Percept? / Jos J. Eggermont -- Human Brain Imaging of Tinnitus / Jennifer R. Melcher -- The Psychophysics of Tinnitus / Brian C. J. Moore -- Stimulating the Auditory System to Treat Tinnitus: From Alleviating the Symptoms to Addressing the Causes / Arnaud J. Noreña -- Treatment: Pharmacological, Repetitive Transcranial Magnetic Stimulation, Epidural Stimulation, and Deep Brain Stimulation / Berthold Langguth, Dirk De Ridder, Tobias Kleinjung and Ana Belén Elgoyhen.
  • 2007 ScienceDirect
    edited by B. Langguth ... [et al.].
  • 2011 AccessMedicine
    2012 AccessEmergency Medicine
    editor-in-chief, Judith E. Tintinalli ; co-editors, J. Stephan Stapczynski ... [et al.].
    Section 1. Prehospital Care -- Section 2. Disaster Preparedness -- Section 3. Resuscitation -- Section 4. Resuscitative Procedures -- Section 5. Analgesia, Anesthesia, and Procedural Sedation -- Section 6. Emergency Wound Management -- Section 7. Cardiovascular Disease -- Section 8. Pulmonary Emergencies -- Section 9. Gastrointestinal Emergencies -- Section 10. Renal and Genitourinary Disorders -- Section 11. Obstetrics and Gynecology -- Section 12. Pediatrics -- Section 13. Infectious Diseases -- Section 14. Neurology -- Section 15. Toxicology -- Section 16. Environmental Injuries -- Section 17. Endocrine Emergencies -- Section 18. Hematologic and Oncologic Emergencies -- Section 19. Eyes, Ears, Nose, Throat, and Oral Surgery -- Section 20. Skin Disorders -- Section 21. Trauma -- Section 22. Injuries to Bones and Joints -- Section 23. Musculoskeletal Disorders -- Section 24. Psychosocial Disorders -- Section 25. Abuse and Assault -- Section 26. Special Situations -- Section 27. Principles of Imaging. Videos of Procedures: -- Dix-Hallpike Maneuver (4 min., 55 sec.) -- Epley Maneuver (3 min., 52 sec.) -- Ultrasound: Basilic Vein Cannulation (5 min., 17 sec.) -- The Knee Exam (10 min., 52 sec.) -- Lumbar Puncture Decubitus Position (10 min., 11 sec.) -- NIH Stroke Scale (18 min., 3 sec.) -- Posterior Leg Splint (2 min., 19 sec.) -- Chest Tube Insertion (10 min.).
  • 7th/8th ed. 2011 AccessEmergency Medicine
    edited by Judith E. Tintinalli, J. Stephan Stapczynski, O. John Ma, David M. Cline, Rita K. Cydulka, Garth D. Meckler, The American College of Emergency Physicians.
    Advanced airway support -- Arrhythmia management -- Resuscitation of children and neonates -- Fluids, electrolytes, and acid-base disorders -- Therapeutic approach to the hypotensive patient -- Anaphylaxis, acute allergic reactions, and angioedema -- Acute pain management and procedural sedation -- Management of patients with chronic pain -- Evaluation and preparing wounds -- Methods for wound closure -- Lacerations to the face and scalp -- Injuries of the arm, hand, fingertip, and nail -- Lacerations to the leg and foot -- Soft tissue foreign bodies -- Puncture wounds and mammalian bites -- Post repair wound care -- Chest pain: cardiac or not -- Acute coronary syndromes: management of myocardial infarction and unstable angina -- Cardiogenic shock -- Low probability acute coronary syndromes -- Syncope -- Congestive heart failure and acute pulmonary edema -- Valvular emergencies -- The cardiomyopathies, myocarditis, and pericardial disease -- Thromboembolism -- Systemic and pulmonary hypertension -- Aortic dissection and aneurysms -- Occlusive arterial disease -- Respiratory distress -- Bronchitis, pneumonia, and SARS -- Tuberculosis -- Spontaneous and latrogenic pneumothorax -- Hemoptysis -- Asthma and chronic obstructive pulmonary disease -- Acute abdominal pain -- Nausea and vomiting -- Disorders presenting primarily with diarrhea -- Acute and chronic constipation -- Gastrointestinal bleeding -- Esophageal emergencies -- Peptic ulcer disease and gastritis -- Pancreatitis and cholecystitis -- Acute appendictis -- Diverticulitis -- Intestinal obstruction and volvulus -- Hernia in adults and children -- Anorectal disorders -- Jaundice, hepatic disorders, and hepatic failure -- Complications of general surgical procedures -- Acute renal failure -- Rhabdomyolysis -- Emergencies in renal failure and dialysis patients -- Urinary tract infections and hematuria -- Acute urinary retention -- Male genital problems -- Urologic stone disease -- Complications of urologic devices -- Vaginal bleeding and pelvic pain in the nonpregnant patient -- Ectopic pregnancy and emergencies in the first 20 weeks -- Comorbid diseases in pregnancy -- Emergencies after 20 weeks pregnancy and the postpartum period -- Emergency delivery -- Vulvovaginitis -- Pelvic inflammatory disease and tube-ovarian abscess -- Complications of gynecologic procedures -- Fever and serious bacterial illness in children -- Common neonatal problems -- Common infections of the ear, nose, neck, and throat -- Upper respiratory emergencies-stridor and drooling -- Wheezing in infants and children -- Pneumonia in infants and children -- Pediatric heart disease -- Vomiting and diarrhea infants and children -- Pediatric abdominal emergencies -- Pediatric urinary tract infections -- Seizures and status epilepticus in children -- Headache and altered mental status in children -- Syncope and sudden death in children and adolescents -- Hypoglycemia and metabolic emergencies in infants and children -- The diabetic child -- Fluid and electrolye therapy -- Musculoskeletal disorders in children -- Rashes in infants and children -- Sickle cell anemia in children -- Hematologic-oncologic emergencies in children -- Renal emergencies in infants and children -- Sexually transmitted diseases -- Toxic shock -- Septic shock -- Soft tissue infections -- Disseminated viral infections -- HIV infections and AIDS -- Infective endocarditis -- Tetanus and rabies -- Malaria -- Foodborne and waterborne diseases -- Zoonotic infections -- World travelers -- The transplant patient -- General management of the poisoned patient -- Anticholinergic toxicity -- Psychopharmacologic agents -- Sedatives and hypnotics -- Alcohols -- Drugs of abuse -- Analgesics -- Xanthines and nicotine -- Cardiac medications -- Anticonvulsants -- Iron -- Hydrocarbons and volatile substances -- Caustics -- Pesticides -- Metals and metalloids -- Industrial toxins and cyanide -- Herbals and vitamins -- Dyshemoglobinemias -- Frostbite and hypothermia -- Heat emergencies -- Bites and stings -- Trauma and envenomation from marine fauna -- High-altitude medical problems -- Dysbarism and complications of diving -- Near drowning -- Thermal and chemical burns -- Electrical and lightning injuries -- Carbon monoxide -- Mushroom and plant poisoning -- Diabetic emergenices -- Alcoholic ketoacidosis -- Thyroid disease emergencies -- Adrenal insufficiency and adrenal crisis -- Evaluation of anemia and the bleeding patient -- Acquired bleeding disorders -- Hemophilias and von Willebrand disease -- Sickle cell disease and other hereditary hemolytic anemias -- Transfusion therapy -- Anticoagulants, antiplatelet agents, and fibrinolytics -- Emergency complications of malignancy -- Headache and facial pain -- Stroke, transient ischemic attack, and subarachnoid hemorrhage -- Altered mental status and coma -- Ataxia and gait disturbances -- Vertigo and dizziness -- Seizures and status epilepticus in adults -- Acute peripheral neurological lesions -- Chronic neurologic disorders -- Central nervous system and spinal infections -- Ocular emergeinces -- Face and jaw emergencies -- Oral and dental emergencies -- Neck and upper airway disorders -- Dermatologic emergencies -- Other dermatologic disorders -- Trauma in adults -- Trauma in children -- Trauma in the elderly -- Trauma in pregnancy -- Head trauma in adults and children -- Spine and spinal cord injuries in adults and children -- Facial injuries -- Trauma to the neck -- Cardiothoracic trauma -- Abdominal injuries -- Penetrating trauma to the flank and buttocks -- Genitourinary injuries -- Penetrating trauma to the extremities -- Initial evaluation and management of orthopedic injuries -- Hand and wrist injuries -- Forearm and elbow injuries -- Shoulder and humerus injuries -- Pelvis, hip, and femur injuries -- Knee and leg injuries -- Ankle and foot injuries -- Compartment syndromes -- Neck and thoracolumbar pain -- Shoulder pain -- Hip and knee pain -- Acute disorders of the joint and bursae -- Emergencies in systemic rheumatic diseases -- Infectious and noninfectious disorders of the hand -- Soft tissue problems of the foot -- Clinical features of behavioral disorders -- Emergency assessment and stabilization of behavioral disorders -- Panic and conversion disorders -- Child and elderly abuse -- Sexual assault and intimate partner violence and abuse.
  • 2005 Springer
    Jean-Louis Dulucq, in collaboration with Pascal Wintringer.
    pt. 1: Upper gastrointestinal tract procedures -- pt. 2: Colorectal procedures -- pt. 3: Inguinal hernia and retroperitoneal procedures -- pt. 4: Procedures for pelvic floor disorders.
  • 2014 Springer
    John C. Watkinson, David M. Scott-Coombes, editors ; Neil Sharma, Michael J. Stechman, Shahzada K. Ahemd, associate editors.
    Endocrine surgery is a highly specialised field due to the technical nature of the procedures and associated risks. Despite this, endocrine operations sometimes fall to the general surgeon to deploy. Tips and Tricks in Endocrine Surgery aims to provide a concise summary of all aspects of endocrine surgery, taking into account the latest evidence and current expert opinion. The book comprises five sections covering the major endocrine organs and systems, each chapter focuses on one endocrine disorder and provides guidelines on the techniques, considerations and aspects of surgical care specific to each procedure. This book is an invaluable quick-reference resource that will appeal to higher surgical trainees in general surgery, endocrine surgery, ENT surgery and neurosurgery. Core surgical trainees preparing for examinations and consultants wishing to refresh their knowledge of the surgical management of endocrine disorders will also find this book useful.
  • 2007 Springer
    Udaya Kumar and Inderbir S. Gill (editors).
    Also available: Print – 2007
  • 2006
    edited by John P. Fisher.
  • 2011 Springer
    Norbert Pallua, Christoph V. Suschek, editors.
    BASICS AND PRINCIPLES: Scaffolds: Micro and Nano Technology -- Biomimetic Materials -- Natural and Synthetic Scaffolds: Adhesion, ECM, Structure, Function, Modification -- Cells: Sources, Growth, Differentiation, Trans-Differentiation -- Embryonic Stem Cells: Sources and Characterization -- Adult Stem Cells: Sources and Characterization -- Isolation and Growth -- Differentiation and Plasticity -- Regulation Mechanisms: Key Signaling Molecules -- Cell and Organ preservation -- Engineering Technologies: Animal Models for Evaluation of Tissue Engineering Constructs -- Biomedical Imaging and Image Processing -- Bioreactors for Tissue Engineering -- Drug delivery -- Gene Therapy -- OROGANS: Liver -- Musculoskeletal Tissues -- Lung -- CNS -- Peripheral Nervous System -- Nephrons -- Biohybrid organs -- Heart and Cardiovascular Engineering -- Eye/Retina -- Respiratory Systems Engineering -- Ear -- Skin -- TISSUE TYPES: Adipose Tissue -- Blood Substitutes -- Angiogenesis and Vascularization -- Bone Tissue -- Brain Tissues -- Cartilage Tissue -- Pancreatic Tissues -- Tendons -- Tissue Engineering in Reproductive Medicine, of Heart Valves, in Oral and Maxillofacial Surgery -- Uro-Gital System/Bladder Tissue.
  • 2006 ScienceDirect
    SU Catalog (SearchWorks) Click LINK above for Print location/circulation status.
    Yoshito Ikada.
  • 2006. CRCnetBASE
    edited by Joseph D. Bronzino.
    Biomolecular engineering in oligonucleotide applications -- Gene therapy -- Bio-nanorobotics: state of the art and future challenges -- sect. IV. Bionanotechnology. DNA as a scaffold for nano-structure assembly -- Directed evolution of proteins for device applications -- Semiconductor quantum dots for molecular and cellular imaging -- Bionanotechnology for bioanalysis -- Nano-hydroxyapatite for biomedical applications -- Nanotechnology provides new tools for biomedical optics -- Nanomaterials perspectives and possibilities in nanomedicine -- Biomedical nanoengineering for nanomedicine -- Physiogenomics: integrating systems engineering and nanotechnology for personalized medicine -- Bionanotechnology patenting: challenges and opportunities -- sect. V. Tissue engineering. Fundamentals of stem cell tissue engineering -- Growth factors and morphogens: signals for tissue engineering -- Extracellular matrix: structure, function, and applications to tissue engineering -- Esophagus: a tissue engineering challenge -- Tissue engineered vascular grafts -- Cardiac tissue engineering: matching native architecture and function to develop safe and efficient therapy -- Tissue engineering of heart valves -- Tissue engineering, stem cells and cloning for the regeneration of urologic organs -- Hepatic tissue engineering for adjunct and temporary liver support -- Tissue engineering of renal replacement therapy -- The bioengineering of dental tissues -- Tracheal tissue engineering -- sect. VI. Prostheses and artificial organs. Artificial heart and circulatory assist devices -- Cardiac valve prostheses -- Vascular grafts -- Artificial lungs and blood-gas exchange devices -- Artificial kidney -- Peritoneal dialysis equipment -- Therapeutic apheresis and blood fractionation -- Liver support systems -- Artificial pancreas -- Nerve guidance channels -- Tracheal, laryngeal, and esophageal replacement devices -- Artificial blood -- Artificial skin and dermal equivalents -- sect. VII. Ethics. Beneficence, nonmaleficence, and medical technology -- Ethical isseus related to clinical research. Mechanical forces on cells -- Cell adhesion -- Cell migration -- Inflammatory and immune responses to tissue engineered devices -- Polymeric scaffolds for tissue engineering applications -- Calcium phosphate ceramics for bone tissue engineering -- Biomimetic materials -- Nanocomposite scaffolds for tissue engineering -- Roles of thermodynamic state and molecular mobility in biopreservation -- Drug delivery -- Gene therapy -- Tissue engineering bioreactors -- Animal models for evaluation of tissue-engineered orthopedic implants -- The regulation of engineered tissues: emerging approaches -- Bioengineering of human skin substitutes -- Nerve regeneration: tissue engineering strategies -- Gene therapy and tissue engineering based on muscle-derived stem cells: potential for musculoskeletal tissue regeneration and repair -- Tissue engineering applications - bone -- Cartilage tissue engineering -- Tissue engineering of the tempormandibular joint -- Engineering smoot muscle -- Sect. I. Molecular biology. Historical perspective and basics of molecular biology -- Systems and technology involving bacteria -- Recombinant DNA technology using mammalian cells -- sect. II. Transport phenomena and biomimetic systems. Biomimetic systems -- Diffusional processes and engineering design -- Microvascular heat transfer -- Perfusion effects and hydrodynamics -- Animal surrogate systems -- Arterial wall mass transport: the possible role of blood phase resistance in the localization of arterial disease -- Control of the microenvironment -- Interstitial transport in the brain: principles for local drug delivery -- sect. III. Biotechnology. Tools for genome analysis -- Vaccine production -- Protein ngineering -- Metabolic engineering -- Monoclonal antibodies and their engineered fragments --
  • 2013 CRCnetBASE
    edited by Murugan Ramalingam, Pekka Vallittu, Ugo Ripamonti and Wan-Ju Li.
    "This book bridges the gap between nanotechnology and regenerative medicine to facilitate their transition from lab to the clinic. It compiles important aspects of the basic science and fundamental principles to current nanotechnological innovations in biomaterials, cell, tissue, and organ engineering, and their clinical relevance, as well as future trends in regenerative medicine. It is intended for a wide audience including students, researchers, professors, and industrial experts working in the tields of biomaterial science and engineering, nanoscience and nanotechnology, bioengineering, cell biology, biomedical sciences, tissue engineering, and nanomedicine"--Provided by publisher.
  • 2010
    editors, James Chang, Gaurav Gupta.
    Status: Not Checked OutLane Catalog Record
    Ch. 1. Tissue Engineering: A Historical Perspective / James D. Kretlow and Antonios G. Mikos -- Ch. 2. Current Clinical Needs in Hand Surgery / L. Scott Levin -- Ch. 3. Principles of Tissue Engineering for Reconstruction of the Hand / Ryosuke Kakinoki -- Ch. 4. Primary Cell Lines and Stem Cells / Katie L. Pricola and Hermann Peter Lorenz -- Ch. 5. Scaffolds / Wei Liu and Yilin Cao -- Ch. 6. Animal Models for Engineering Tissues in the Upper Extremity / Xing Zhao and Mark A. Randolph -- Ch. 7. Guidance Strategies in Hand Tissue Engineering: Manipulating the Microenvironment Through Cellular and Material Cues / Harvey Chim and Arun K. Gosain -- Ch. 8. Bioreactors / Laurence A. Galea and Wayne A. Morrison -- Ch. 9. Nerve Engineering / Gregory H. Borschel -- Ch. 10. Tendon Engineering / Johan Thorfinn, Ioannis Angelidis, Brian Pridgen and James Chang -- Ch. 11. Skin / Deepak M. Gupta, Nicholas J. Panetta, Geoffrey C. Gurtner and Michael T. Longaker -- Ch. 12. Bone and Cartilage / Ashley Rothenberg and Jennifer Elisseeff -- Ch. 13. Blood Vessels / Masayuki Yamato and Teruo Okano -- Ch. 14. Bench to Bedside: Navigating Industry, the FDA and Venture Capital / Nicholas J. Panetta, Deepak M. Gupta, Michael T. Longaker and Geoffrey C. Gurtner.
  • 2011 Springer
    Harold S. Bernstein, editor.
    pt. 1. Stem cells -- pt. 2. Biomaterials and the extracellular environment -- pt. 3. Engineered tissue -- pt. 4. Synthetic organs -- pt. 5. Immune response -- pt. 6. Animal models.
  • 2007 Springer Protocols
    edited by Hansjörg Hauser, Martin Fussenegger.
    In vitro expansion of tissue cells by conditional proliferation -- Stem cell engineering using transducible Cre recombinase -- Human embryonic stem cells for tissue engineering -- Culture and characterization of human bone marrow mesenchymal stem cells -- Skeletal ("Mesenchymal") stem cells for tissue engineering -- Biomaterials/Scaffolds -- Synthetic hydrogel matrices for guided bladder tissue regeneration -- Generation of multicellular tumor spheroids by the hanging-drop method -- In vitro vascularization of human connective microtissues -- Artificial skin -- Small blood vessel engineering -- Artificial pancreas to treat type 1 Diabetes Mellitus -- Human articular chondrocytes culture -- Cardiomyocytes from human and mouse embryonic stem cells -- Myocardial restoration and tissue engineering of heart structures -- Practical aspects of cardiac tissue engineering with electrical stimulation -- Biological scaffolds for heart valve tissue engineering -- In vitro heart valve tissue engineering.
  • 2007 CRCnetBASE
    edited by Aldo R. Boccaccini and Julie E. Gough.
    pt. 1. General issues -- pt. 2. Tissue and organ generation.
  • 2010 Springer Protocols
    edited by Ronald Simon.
    Applications of tissue microarray technology -- Quality aspects of TMA analysis -- Representativity of TMA studies -- Recipient block TMA technique -- Protocol for constructing tissue arrays by cutting edge matrix assembly -- Hypodermic needle without recipient paraffin block technique -- Resin technologies : construction and staining of resin TMA's -- Tissue microarrays from frozen tissues-OCT technique -- An alternative technology to prepare tissue microarray using frozen tissue samples -- Building "tissue" microarrays from suspension cells -- Tissue microarrays from biopsy specimens -- Immunohistochemical analysis of tissue microarrays -- DNA copy number analysis on formalin-fixed paraffin-embedded tissues in TMA format by RNA in situ hybridization -- Automated analysis of tissue microarrays -- Digital microscopy for boosting database integration and analysis in TMA studies -- From gene to clinic : TMA-based clinical validation of molecular markers in prostate cancer
  • 2015 Springer Protocols
    edited by Celeste M. Nelson.
    Probing regional mechanical properties of embryonic tissue using microindentation and optical coherence tomography / Benjamen A. Filas, Gang Xu, and Larry A. Taber -- Hemodynamic flow visualization of early embryonic great vessels using [mu]PIV / Selda Goktas, Chia-Yuan Chen, William J. Kowalski, and Kerem Pekkan -- Using correlative light and electron microscopy to study Zebrafish vascular morphogenesis / Jacky G. Goetz, Fabien Monduc, Yannick Schwab, and Julien Vermot -- Micro/nano-computed tomography technology for quantitative dynamic, multi-scale imaging of morphogenesis / Chelsea L. Gregg, Andrew K. Recknagel, and Jonathan T. Butcher -- Imaging the dorsal-ventral axis of live and fixed Drosophila melanogaster embryos / Sophia N. Carrell and Gregory T. Reeves -- Light sheet-based imaging and analysis of early embryogenesis in the fruit fly / Khaled Khairy [and three others] -- Quantitative image analysis of cell behavior and molecular dynamics during tissue morphogenesis / Chun Yin Bosco Leung and Rodrigo Fernandez-Gonzalez -- A multiplex fluorescent in situ hybridization protocol for clonal analysis of Drosophila oogenesis / Lily S. Cheung and Stanislav Shvartsman -- Active cell and ECM movements during development / Anastasiia Aleksandrova [and three others] -- 3D culture assays of murine mammary branching morphogenesis and epithelial invasion / Kim-Vy Nguyen-Ngoc [and five others] -- Culture of mouse embryonic foregut explants / Felicia Chen and Wellington V. Cardoso -- Investigating human vascular tube morphogenesis and maturation using endothelial cell-pericyte co-cultures and a doxycycline- inducible genetic system in 3D extracellular matrices / Stephanie L.K. Bowers [and three others] -- Three-dimensional traction force microscopy of engineered epithelial tissues / Alexandra S. Piotrowski [and three others] -- Probing cell mechanics with subcellular laser dissection of actomyosin networks in the early developing Drosophila embryo / M. Rauzi and P.-F. Lenne -- UV laser ablation to measure cell and tissue-generated forces in the Zebrafish embryo in vivo and ex vivo / Michael Smutny [and four others] -- Measurement of intercellular cohesion by tissue surface tensiometry / Ramsey A. Foty -- Quail-chick chimeras and eye development / Sinu Jasrapuria Agrawal and Peter Y. Lwigale -- Studying epithelial morphogenesis in Dictyostelium / Daniel J. Dickinson, W. James Nelson, and William I. Weis -- Primary cell cultures of regenerating Holothurian tissues / Samir A. Bello, Ricardo J. Abreu-Irizarry, and José́ E. Garcı́a-Arrarás -- Large-scale parameter studies of cell-based models of tissue morphogenesis using CompuCell3D or VirtualLeaf / Margriet M. Palm and Roeland M.H. Merks -- Simulating tissue morphogenesis and signaling / Dagmar Iber [and four others] -- Elasticity-based targeted growth models of morphogenesis / Patrick W. Alford.
  • 2008 Springer protocols
    edited by Brian C.-S. Liu and Joshua R. Ehrlich.
    Capabilities using 2-D DIGE in proteomics research : the new gold standard for 2-D gel electrophoresis / Christine R. Rozanas and Stacey M. Loyland -- Protein carbohydrate analysis : gel-based staining, liquid chromatography, mass spectrometry, and microarray screening / Injae Shin, Alina D. Zamfir, and Bin Ye -- Surface-enhanced laser desorption/ionization mass spectrometry for protein and peptide profiling of body fluids / Audrey Gagnon, Qian Shi, and Bin Ye -- A novel approach using MALDI-TOF mass spectrometry and prestructured sample supports (AnchorChip technology) for proteomic profiling and protein identification / Sau-Mei Leung and Rebecca L. Pitts -- Automated laser capture microdissection for tissue proteomics / Adrianna S. Rodriguez ... [et al.] -- Tissue microarrays : an overview / Rajiv Dhir -- Frozen protein arrays / Stephen M. Hewitt and Robert A. Star -- Reverse phase protein microarrays for theranostics and patient-tailored therapy / Virginia Espina ... [et al.] -- Antibody arrays for determination of relative protein abundances / Grigoriy S. Chaga -- SH2 domain-based tyrosine phosphorylation array / Xin Jiang ... [et al.] -- Immunoregulomics : a serum autoantibody-based platform for transcription factor profiling / Oliver W. Tassinari ... [et al.] -- The "reverse capture" autoantibody microarray : an innovative approach to profiling the autoantibody response to tissue-derived native antigens / Joshua R. Ehrlich ... [et al.] -- Biorepository standards and protocols for collecting, processing, and storing human tissues / Dean Troyer.
  • 2006 Springer
    [editors] Christine Chaponnier, Alexis Desmoulière, Giulio Gabbiani.
    1. Cytomechanics in connective tissue repair and engineering / Robert A. Brown -- 2. Scleroderma lung fibroblasts : contractility and connective tissue growth factor / Galina S. Bogatkevich ... [et al.] -- 3. Functional assessment of fibroblast heterogeneity by the cell-surface glycoprotein thy-1 / Carolyn J. Baglole ... [et al.] -- 4. Tissue repair in asthma : the origin of airway subepithelial fibroblasts and myofibroblasts / Sabrina Mattoli -- 5. Experimental models to study the origin and role of myofibroblasts in renal fibrosis / Michael Zeisberg, Mary A. Soubasakos and Raghu Kalluri -- 6. Epithelial to mesenchymal transition of mesothelial cells as a mechanism responsible for peritoneal membrane failure in peritoneal dialysis patients / Abelardo Aguilera ... [et al.] -- 7. FIZZy alveolar epithelial cells induce myofibroblast differentiation / Sem H. Phan -- 8. Pro-invasive molecular cross-signaling between cancer cells and myofibroblasts / Olivier De Wever and Marc Mareel -- 9. Proangiogenic implications of hepatic stellate cell transdifferentiation into myofibroblasts induced by tumor microenvironment / Elvira Olaso ... [et al.] -- 10. Matrix metalloproteinases, tissue inhibitors of metalloproteinase and matrix turnover and the fate of hepatic stellate cells / Aqeel M. Jamil and John P. Iredale -- 11. Innate immune regulation of lung injury and repair / Dianhua Jiang ... [et al.] -- 12. An Eye on repair : myofibroblasts in corneal wounds / James V. Jester.
  • 2006 Springer
    Maria Z. Siemionow (ed.).
  • 2013 Springer Protocols
    edited by Pietro Ghezzi, Anthony Cerami.
    Erythropoietin and engineered innate repair activators / Michael Brines and Anthony Cerami -- Epo and non-hematopoietic cells : what do we know / Omolara O. Ogunshola and Anna Yu. Bogdanova -- Tissue-protective cytokines : structure and evolution / Pietro Ghezzi and Darrell Conklin -- Regenerative activity of interleukin-6 / Eithan Galun and Stefan Rose-John -- Brain ischemic injury in rodents : the protective effect of EPO / Annelise Letourneur [and others] -- Experimental traumatic spinal cord injury / Zubeyde Erbayraktar [and others] -- Erythropoietin as a neuroprotectant for beonatal brain injury : animal models / Christopher M. Traudt and Sandra E. Juul -- Evaluating effects of EPO in rodent behavioral assays related to depression / Catharine H. Duman and Samuel S. Newton -- Erythropoietin and cytoprotective cytokines in experimental traumatic brain injury / Samson Kumar Gaddam, Jovany Cruz, and Claudia Robertson -- Therapeutic efficacy of erythropoietin in experimental autoimmune encephalomyelitis in mice, a model of multiple sclerosis / Ilaria Cervellini, Pietro Ghezzi, and Manuela Mengozzi -- Deciphering the intracellular signaling of erythropoietin in neuronal cells / Murat Digicaylioglu -- Assessment of allodynia relief by tissue-protective molecules in a rat model of nerve injury-induced neuropathic pain / Maarten Swartjes, Marieke Niesters, and Albert Dahan -- Intra-epidermal nerve fibers density and nociception in EPO-treated type 1 diabetic rats with peripheral neuropathy / Bianchi Roberto [and others] -- ARA290 in a rat model of inflammatory pain / Andrew Dilley -- In vivo angiogenic activity of erythropoietin / Domenico Ribatti -- Photoreceptor degeneration in mice : adeno-associated viral vector-mediated delivery of erythropoietin / Pasqualina Colella and Alberto Auricchio -- Myocardial infarction : cardioprotection by erythropoietin / Mark I. Talan and Roberto Latini -- Using plethysmography to determine erythropoietin's impact on neural control of ventilation / Tommy Seaborn, Max Gassmann, and Jorge Soliz -- Cerebral malaria : protection by erythropoietin / Anne-Lise Bienvenu and Stephane Picot.
  • 2007 Springer
    K.S. KOrach, T. Wintermantel, editors.
  • 2010 Karger
    volume editors, G. Kollias, P.P. Sfikakis.
    TNF is a multifunctional proinflammatory cytokine central to the development and homeostasis of the immune system and a regulator of cell activation, differentiation and death. Recent decades have seen an enormous scientific and clinical interest in the function of TNF in physiology and disease. A vast amount of data has been accumulated at the biochemical, molecular and cellular level, establishing TNF as a prototype for in-depth understanding of the physiological and pathogenic functions of cytokines. This volume covers several current aspects of TNF regulation and function, including transcriptional and posttranscriptional control mechanisms, cellular modes of action, signaling networks that mediate its effect, involvement in pathogenesis and clinical outcomes of TNF antagonists. It combines basic science at the molecular and cellular level with research in animal models of disease and clinical findings to provide a comprehensive review of recent developments in TNF biology. A thorough understanding of the mechanisms by which this key molecular player is produced and functions to regulate cell biology, immunity and disease postulates novel paradigms on how genes contribute to the development and physiology of biological systems.
  • 2007 Springer
    edited by Hao Wu.
    Phylogeny of the TRAF/math domain / Juan M. Zapata, Vanesa Martínez-García, and Sophie Lefebvre -- TRAF1 and its biological functions / Soo Young Lee and Yongwon Choi -- Physiological roles and mechanisms of signaling by TRAF2 and TRAF5 / Ping-Yee Billie Au and Wen-Chen Yeh -- TRAF3 and its biological function / Jeannie Q. He ... [et al.] -- TRAF4, the unique family member / Valérie Kedinger and Marie-Christine Rio -- Characteristics and biological functions of TRAF6 / Jun-ichiro Inoue, Jin Gohda and Taishin Akiyama -- Ubiquitination and TRAF signaling / Gabriel Pineda, Chee-Kwee Ea and Zhijian J. Chen -- Structural revelations of TRAF2 function in TNF receptor signaling pathway / Jee Y. Chung ... [et al.] -- Protein-protein interactions in TRAF3 / Kathryn R. Ely, Ramadurgam Kodandapani and ShuangDing Wu -- Molecular basis for the unique specificity of TRAF6 / Jee Y. Chung ... [et al.] -- TRAF proteins in CD40 signaling / Gail A. Bishop ... [et al.] -- TRAFs in rank signaling / Bryant G. Darnay ... [et al.] -- The LT[beta]R signaling pathway / Paula S. Norris and Carl F. Ware -- LMP1 trafficking activates growth and survival pathways / Vishal Soni, Ellen Cahir-McFarland and Elliott Kieff -- Targeting TRAFs for therapeutic intervention / Juan M. Zapata, Sophie Lefebvre and John C. Reed.
    Also available: Print – 2007
  • 2014 Springer Protocols
    edited by Jagadeesh Bayry, INSERM Unité 1138, Paris, France.
    Assaying NF-[kappa]B activation and signaling from TNF receptors -- Dissecting DR3 signaling -- Modulation of fc[epsilon]RI-dependent mast cell response by OX40L -- Analyzing the signaling capabilities of soluble and membrane TWEAK -- Regulation of human dendritic cell functions by natural anti-cd40 antibodies -- [Beta]-actin in the signaling of transmembrane TNF-[alpha]-mediated cytotoxicity -- Investigating the protective role of death receptor 3 (DR3) in renal injury using an organ culture model -- Analysis of TNF-[alpha]-mediated cerebral pericyte remodeling -- CD137 in chronic graft-versus-host disease -- In vitro investigation of the roles of the proinflammatory cytokines tumor necrosis factor-[alpha] and interleukin-1 in murine osteoclastogenesis -- Evasion of TNF-[alpha]-mediated apoptosis by hepatitis C virus -- TNF-[alpha] modulates TLR2-dependent responses during mycobacterial infection -- Experimental applications of TNF-reporter mice with far-red fluorescent label -- A solid-phase assay for studying direct binding of progranulin to TNFR and progranulin antagonism of TNF/TNFR interactions -- Compartment-specific flow cytometry for the analysis of TNF-mediated recruitment and activation of glomerular leukocytes in murine kidneys -- Determination of soluble tumor necrosis factor receptor 2 produced by alternative splicing -- Effective expression and purification of bioactive recombinant soluble LIGHT -- One of the TNF superfamily members: Bifunctional protein, TNFR2-Fc-IL-1ra.
  • 2006 Springer
    edited by J.M. Weinberg and R. Buchholz.
  • 2013
    The gradual increase in longevity in the United States and elsewhere has already brought about a slow-motion revolution in nearly every sector of society, from health care to housing to employment. But if radical life extension moves from the realm of fantasy to reality, that revolution will pick up considerable speed. Extending human life spans beyond those of even the oldest of our ancestors would raise a host of new social, political, economic, environmental, moral and other questions. Religious organizations have traditionally played an important role in helping people think through end-of-life matters and respond to significant social changes. But since life extension has not made the journey from fantasy to fact, there has been little official or even quasi-official guidance in this area from churches and other religious groups.
  • 2013
    Mercedes Graf.
    Pioneer women doctors campaign for wartime service -- From pioneer women doctors abroad to "joining the home team" -- From contract surgeon to Army medical officer -- Enter the women neuropsychiatrists/psychiatrists -- "Specialization as a mark of expertise": women doctors in internal medicine, pathology, anesthesiology, and orthopedics -- "Narrowing the field": women doctors in radiology, preventive medicine, surgery, and other areas -- More than they expected: nonspecialists and other problems in service -- "I do not regret having had the opportunity to serve my country": a look back at women's experiences as medical officers in the United States Army -- Appendix.
  • 2013
    edited by Jonathan Weigel ; foreword by President Bill Clinton.
    "Here are highlights from Paul Farmers' speeches to a variety of audiences, from Princeton to Harvard to Notre Dame to Berkeley. Paul is a rock star of the academy who has a large following among many groups: students, doctors, general readers, activists, public health folks, professors. He is the pied piper of everyone who wants to change the world. Not only is he cofounder of Partners In Health,US Deputy Special Envoy to Haiti, head of social medicine at Harvard, but he's also a charming, humorous, engaging public speaker whose charisma is legend. In this book, conceived of as a graduation gift for students write large, Farmer addresses the challenges facing young people with a call for them to change the world and become activists."-- [Provided by publisher]
  • 1835? NLM
    Medical Department of the Cincinnati College.
  • 2011
    Ruth Ilana Tennen.
    Saccharomyces cerevisiae silent information regulator 2 (Sir2) is an NAD+-dependent histone deacetylase that links chromatin silencing to genomic stability, cellular metabolism, and lifespan regulation. The human Sir2 family member SIRT6 is a highly substrate-specific histone deacetylase that promotes proper chromatin function in several physiologic contexts, including preserving telomere integrity, fine-tuning gene expression programs, preventing genomic instability, and maintaining metabolic homeostasis. Here, we describe work aimed at expanding the molecular and cellular understanding of SIRT6. First, we report the identification of novel functions for the N- and C-terminal domains of SIRT6. We show that the C-terminal extension (CTE) of SIRT6 contributes to proper nuclear localization; the N-terminal extension (NTE) is critical for chromatin association and intrinsic catalytic activity; and mutation of a conserved catalytic histidine residue in the core sirtuin domain not only abrogates SIRT6 enzymatic activity but also leads to impaired chromatin association in cells. Second, we show that SIRT6 is required for maintenance of telomere-proximal gene silencing--a phenomenon termed telomere position effect (TPE)--in human cells. RNAi-mediated depletion of SIRT6 abrogates silencing of both an integrated telomeric transgene and an endogenous telomere-proximal gene. Moreover, enhanced telomeric silencing in response to telomere elongation is associated with increased repressive chromatin marks, and this heterochromatic milieu is lost in SIRT6-deficient cells. Together, these studies provide new insight into the molecular mechanism of SIRT6 activity; uncover a novel role for SIRT6 in regulating telomeric gene silencing; and reveal important links between SIRT6 and disease-relevant cellular processes.
  • 2010 OSO, Limited to 3 simultaneous users
    edited by Peter Boyle, Nigel Gray, Jack Henningfield, John Seffrin, and Witold Zatonski.
    "Comprehensively covers the science and policy issues relevant to one of the major public health disasters of modern times. It pulls together the etiology and burden of the myriad of tobacco-related diseases with the successes and failures of tobacco control policies. The book looks at lessons learnt to help set health policy for reducing the burden of tobacco-related diseases. It also deals with the international public health policy issues which bear on control of the problem of tobacco use and which vary between continents."--Publisher's description
  • 2009
    Eugene Umberger.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    edited by T. Nagata, K. Matsuoka and D. Inze.
  • 2016 Springer
    Byron C. Calhoun, Tammi Lewis, editors.
    Introduction: Abuse of Tobacco and Substances -- Physiology of Nicotine -- Physiology of EtOH and Opiate Receptors -- Women's Specific Issues -- Health Effects -- Pregnancy Effects -- Tobacco Cessation -- Addictions Counseling -- Therapeutic Substitution -- Appendix: Protocols and Guidelines.
  • 2015 Karger
    volume editors, Robert Loddenkemper, Michael Kreuter.
    History of tobacco production and use / Hanafin, J., Clancy, l. -- Global tobacco epidemic / Mackay, J., Schluger, N. -- The tobacco epidemic and the commercial sector : tobacco industry strategies to increase profits and prevent regulation / Weishaar, H. -- Chemistry and primary toxicity of tobacco and tobacco smoke / Wiebel, F.J. -- Nicotine dependence / Zaveri, N., Rollema, H., Swan, G.E. -- The psychology of the smoker / Gilbert, D.G., Pergadia, M.L. -- Respiratory disorders related to smoking tobacco / Murray, J.F., Buist, A.S. -- Cardiovascular and other (except respiratory) disorders related to smoking tobacco / Barnoya, J., Monzon, J.C. -- Health effects of passive smoking in children / Bush, A. -- Health effects of passive smoking in adults / Kabir, Z., Clancy, L. -- Economics of tobacco use and control / Townsend, J. -- Legislation and smoking prevention / Latif, E., Warner, V. -- The WHO framework convention on tobacco control / Poetschke-Langer, M., Schotte, K., Zilagyi, T. -- Youth and tobacco / Bauer, C., Kreuter, M. -- Impact of media, movies and TV on tobacco use in the youth / Sargent, J.D., Hanewinkel, R. -- Social determinants of cigarette smoking / Upson, D. -- Smoking and mental health problems / Caill-Garnier, S., Baker, A.L, Todd, J., Turner, A., Dayas, C. -- Patterns and predictors of smoking cessation / Ditre, J.W., Zale, E.L., Brandon, T.H. -- Examining the role of the health care professional in controlling the tobacco epidemic : individual, organizational and institutional responsibilities / Leone, F.T., Evers-Casey, S. -- Pharmacotherapy : nicotine replacement therapy and other drugs in smoking cessation (including vaccination) / Tonnesen, P. -- Smokeless tobacco : health hazards or less harm? / Bolinder, G., Gilljam, H. (stockholm) -- Waterpipe tobacco smoking : a less harmful alternative? / Jawad, M. -- Electronic cigarettes : the issues behind the moral quandary / Vardavas, C.I., Agaku, I.T.
  • 2006
    guest editors, Virginia Cullen Reichert, Arunabh Talwar, Alan M. Fein.
    Trends in tobacco use -- Financial burden of tobacco use: an employer's perspective -- The impact of tobacco use and secondhand smoke on hospitality workers -- Tobacco and law enforcement officers -- Tobacco and the health care industry -- Tobacco and the movie industry -- Current tobacco control policy trends in the United States -- Current trends in international tobacco control -- Tobacco and carcinogens in the workplace -- Respiratory health consequences of environmental tobacco smoke -- Pulmonary and cardiovascular consequences of smoking -- Smoking and systemic disease -- Tobacco and HIV.
  • 2009 CRCnetBASE
    edited by Ronald Ross Watson, Victor R. Preedy.
    Introduction and overview. Tocotrienols : a review / Alexander G. Schauss Tocotrienols in vitamin E : hype or science? / Neil E. Levin and Dallas L. Clouatre -- Sources. Tocotrienols : distribution and sources cereals-role in human health / Henryk Zielinski -- Tocotrienols in plants : sources and importance / Liva Harinantenaina -- Vitamin E : natural vs. synthetic / Amy Kosowski and Dallas L. Clouatre -- Chemistry of tocotrienols. Angiogenesis inhibition / Kiyotaka Nakagawa ... [et al.] -- Chemistry of tocotrienols / Sanchita P. Ghosh, Martin Hauer-Jensen, and K. Sree Kumar -- Mechanisms of action. Antioxidant activity of tocotrienols in cells and serum / Rossella Simone and Paola Palozza -- Antioxidant action of tocotrienols and tocopherols in solution and membranes : chemical and physical effects / Yasukazu Yoshida and Etsuo Niki -- Antiproliferative and apoptotic effects of tocotrienols on normal and neoplastic mammary epithelial cells / Paul W. Sylvester -- DNA polymerase inhibition / Yoshiyuki Mizushina, Hiromi Yoshida and Teruo Miyazawa -- Tocotrienols in altering the expression of adhesion molecules / Yuji Naito and Toshikazu Yoshikawa -- Uptake, distribution and protective action of tocotrienols in cultured cells / Noriko Noguchi, Yoshiro Saito and Etsuo Niki. Cancer prevention and treatment. Anticancer effects of tocotrienols and tocopherols irrespective of anti-oxidative properties / Tomohiro Yano and Nantiga Virgona -- Role of the mevalonate pathway in tocotrienol-mediated tumor suppression / Huanbiao Mo and Charles E. Elson -- Telomerase inhibition / Takahiro Eitsuka, Kiyotaka Nakagawa and Teruo Miyazawa -- Heart disease. Tocopherol and tocotrienols : role in heart disease care and prevention / Vijaya Juturu -- Tocotrienols and the regulation of cholesterol biosynthesis / Jiao Cao, Wei Qi and Bao-Liang Song -- Tocotrienols in cardiometabolic diseases / Barrie Tan and Anne M. Mueller -- Tocotrienols in hyperlipidemic conditions / Jahangir Iqba1 and Mohammad Minhajuddin -- Vitamin E isomers, tocotrienols, in cardioprotection / Samarjit Das, Manika Das and Dipak K. Das -- Metabolism and absorption. Absorption and disposition of tocotrienols / Kah-Hay Yuen, Bee-Hong Ng and Jia-Woei Wong -- The metabolism of tocopherols and tocotrienols and novel functions of their metabolites / Qing Jiang -- Tocotrienols activate the steroid and xenobiotic receptor SXR to modulate small molecule metabolism / Kameran R. Johnson, Tiffany Hsu, and Bruce Blumberg. Health promotion. Tocotrienols in the potential treatment of infectious disease / Anne M. Mueller, Barrie Tan and Elizabeth S. Stuart -- Tocotrienols as natural neuroprotective vitamins / Chandan K. Sen, Savita Khanna and Sashwati Roy -- Gamma-tocotrienol : potential as a countermeasure against radiological threat / K. Sree Kumar, Sanchita P. Ghosh and Martin Hauer-Jensen.
    Also available: Print – 2009
  • 2013 CRCnetBASE
    edited by Barrie Tan, Ronald Ross Watson, Victor R. Preedy.
    "A New Avenue of Research Beyond Traditional Studies of Vitamin E. The first 90 years of vitamin E research has produced prolific and notable discoveries. Until the last few decades, attention has been given mostly to the biological activities and underlying mechanisms of alpha-tocopherol, which we now know is one of more than eight vitamin E isomers. Tocotrienol discovery came much later, in 1965, but existed for almost 20 years as an obscure vitamin E. Explores Treatment Possibilities: Tocotrienols have proven to contain some exceptional benefits that aren't shared by the better known tocopherols. Although both are antioxidants, today a bright spot for tocotrienol research is in cancer and heart disease, while emergent fields of tocotrienol research are on the rise with many covered in this edition. Currently, tocotrienols have reached a new measure of research height: more than one-third of all vitamin E tocotrienol research of the last 30 years was published in the last 3 years. The thriving field of tocotrienol research gives ground for publication of this 2nd edition, a compilation of the latest tocotrienol research in all new chapters. For the past 10 years, Professors Ronald R. Watson and Victor R. Preedy have published books on bioactive nutrients and dietary supplements. Professor Watson has been and is currently funded to do research by grants from the American Heart Foundation and the U.S. National Institute of Heart, Lung, and Blood. By gathering the contributions contained in this volume, they have expanded the field of knowledge and forged a new path in disease treatment and prevention"--Provided by publisher.
  • Todar, Kenneth Gregory.
    Evolved from online and live-in-person lectures presented in bacteriology courses at the University of Wisconsin-Madison. New material is constantly being added, and current material is constantly being revised and updated.--Website
  • 2010
    Karen A. McWhirt.
    Status: Not Checked OutLane Catalog Record
    At the age of 20, a young man tells his story of his diagnosis of testicular cancer, and shares the pains and struggles he endured while undergoing intense chemotherapy and radiation treatments due to his late-stage diagnosis. A true testimony of the importance of talking about the disease in our society, and what happens if testicular cancer gets overlooked for too long. Ian's story stresses that catching the disease when it is in early stages is essential to avoid intense treatments and increase the chance of survival. It is a warning to all young men to be proactive in their own testicular health and learn about testicular cancer, the most common and curable cancer in young men, in order to avoid the fate that Ian suffered. The final chapter includes medical image explaining testicular cancer metastasis, facts about the disease, its symptoms, and how to perform a testicular self-examination.
  • 2005 Springer
    [edited by] Tina Rich.
    Introduction: toll receptors and the renaissance of innate immunity / Elizabeth H. Bassett and Tina Rich -- The function of toll-like receptors / Zlatko Dembic -- Structures and motifs involved in toll signaling / Monique Gangloff, Phumzile L. Ludidi and Nicholas J. Gay -- "Supramolecular" activation clusters in innate immunity / Martha Triantafilou and Kathy Triantafilou -- Interleukin-I receptor/toll-like receptor signaling / Harald Wajant, Peter Scheurich and Frank Henkler -- Virus induced signaling to initiate the interferon mediated anti-viral host response / Claudia Wietek and Luke A.J. O'Neill -- The induction of dendritic cell activation and maturation by toll-like receptor signaling / Tsuneyasu Kaisho and Shizuo Akira -- Pathogen avoidance using toll signaling in C. elegans / Nathalie Pujol and Jonathan J. Ewbank -- Forward genetic analysis of TLR pathways: a shared system for the detection of endotoxin and viral infection / Bruce Beutler ... [et al.] -- Agonists of toll-like receptor 9: modulation of host immune responses with synthetic oligodeoxynucleotides / Ekambar R. Kandimalla and Sudhir Agrawal.
  • 2009/2010
    Angela Landrigan.
    Status: Not Checked OutLane Catalog Record
  • 2009 Springer
    Tammy Kielian, editor.
    Overview of toll-like receptors in the CNS / Tammy Kielian -- Toll-like receptors in bacterial meningitis / Uwe Koedel -- Toll-like receptors in brain abscess / Nilufer Esen and Tammy Kielian -- Toll-like receptors in CNS viral infections / Hyeon-Sook Suh, Celia F. Brosnan and Sunhee C. Lee -- Toll-like receptors in CNS parasitic infections / Bibhuti B. Mishra, Uma Mahesh Gundra and Judy M. Teale -- Toll-like receptors in neurodegeneration / Trevor Owens -- Toll-like receptors in spinal cord injury / Kristina A. Kigerl and Phillip G. Popovich -- Toll-like receptors in Alzheimer's disease / Gary E. Landreth and Erin G. Reed-Geaghan -- Toll-like receptors in multiple sclerosis / Michael K. Racke and Phil D. Drew -- Toll-like receptors in peripheral nerve injury and neuropathic pain / Donghoon Kim, Soojin Lee and Sung Joong Lee.
    Also available: Print – 2009
  • 2005 Springer
    Luke A.J. O'Neill, Elizabeth Brint, editors.
    Also available: Print – 2005
  • 2008 Springer
    Stefan Bauer, Gunther Hartmann, editors ; contributors, S. Akira ... [et al.].
  • 1997 Wiley
    1997 IEEE
    Richard M. Reis ; IEEE Education Society, sponsor.
    "Tomorrow's Professor is designed to help you prepare for, find, and succeed at academic careers in science and engineering. It looks at the full range of North American four-year academic institutions while featuring 30 vignettes and more than 50 individual stories that bring to life the principles and strategies outlined in the book. Tailored for today's graduate students, postdocs, and beginning professors, Tomorrow's Professor: Presents a no-holds-barred look at the academic enterprise; Describes a powerful preparation strategy to make you competitive for academic positions while maintaining your options for worthwhile careers in government and industry; Explains how to get the offer you want and start-up package you need to help ensure success in your first critical years on the job; Provides essential insights from experienced faculty on how to develop a rewarding academic career and a quality of life that is both balanced and fulfilling. At a time when anxiety about academic career opportunities for Ph. D.s in these field is at an all-time high, Tomorrow's Professor provides a much-needed practical approach to career development."--Publisher's description.
  • 2014 CRCnetBASE
    edited by, Ingrid Reiser, Stephen Glick.
    "Preface For much of the past century, projection radiography has been the workhorse in the diagnostic imaging clinic. Tomosynthesis, which introduces depth information to the x-ray radiographic image with little or no increase in radiation dose, could potentially replace projection radiography as we move into the twenty-first century. This book, Tomosynthesis Imaging, offers the most comprehensive resource to date for this new emerging imaging technology. Digital tomosynthesis imaging is a novel quasi-three dimensional x-ray imaging modality that has been primarily developed during the past two decades, owing to the availability of large-area digital x-ray detectors. The tomosynthesis image is reconstructed from a sequence of projection images that are acquired from a limited angle x-ray scan, therefore, conceptually, tomosynthesis might be considered as limited-angle CT. Because of the limited angle acquisition, resolution in the reconstructed volume is not isotropic. The resolution in image planes parallel to the detector surface is similar to the native detector resolution, but the resolution perpendicular to the detector surface direction is substantially worse, and depends on the scan arc length and on the size of the detail being imaged. Tomosynthesis imaging is being actively investigated for use in a variety of clinical tasks. Currently, tomosynthesis breast imaging is at the forefront, having received approval for clinical use in Europe and Canada in 2008, and FDA approval in the United States in 2011. Although conventional mammography has been very successful in reducing the breast cancer mortality rate, its sensitivity and specificity are less then desirable, especially for women with dense breast tissue"--Provided by publisher.
  • 2016 Karger
    volume editors, Alpdogan Kantarci, Leslie Will, Stephen Yen.
    Section 1. Biology and metabolism of alveolar bone -- Section 2. Mechanical properties of dentoalveolar structures -- Section 3. Orthodontic tooth movement -- Section 4. Methods to facilitate orthodontic tooth movement.
  • 2013 Karger
    volume editor, Cor van Loveren.
    An introduction to toothpaste : its purpose, history, and ingredients / Lippert, F. -- Fluorides and non-fluoride remineralization systems / Amaechi, B.T., van Loveren, C. -- Antiplaque and antigingivitis toothpastes / Sanz, M., Serrano, J.; Iniesta, M.; Santa Cruz, I., Herrera, D. -- The role of toothpastes in oral malodor management / Dadamio, J., Laleman, I., Quirynen, M. -- Anti-calculus and whitening toothpastes / van Loveren, C., Duckworth, R.M. -- The role of toothpaste in the aetiology and treatment of dentine hypersensitivity / Addy, M., West, N.X. -- Toothpaste and erosion / Ganss, C., Schulze, K., Schlueter, N. -- Abrasivity testing of dentifrices : challenges and current state of the art / González-Cabezas C., Hara, A., Hefferren, J., Lippert, F. -- Laboratory and human studies to estimate anticaries efficacy of fluoride toothpastes / Tenuta, L.M.A., Cury, J.A. -- Pharmacokinetics in the oral cavity : fluoride and other active ingredients / Duckworth, R.M. -- After-brush rinsing protocols, frequency of toothpaste use : fluoride and other active ingredients / Parnell, C., O'Mullane, D.
  • 2015 Thieme-Connect
    William T. O'Brien.
    Congenital and developmental -- Attenuation and signal abnormality -- Masses and masslike lesions -- Vasculature and cerebrospinal fluid spaces -- Calvarium and skull base -- Temporal bone -- Sinonasal -- Maxillofacial -- Neck (including spaces) -- Orbits.
  • 2010 Thieme Book
    edited by William T. O'Brien.
    Chest and cardiac imaging -- Gastrointestinal imaging -- Genitourinary imaging -- Musculoskeletal imaging -- Head and neck imaging -- Brain and spine imaging -- Pediatric imaging -- Ultrasound imaging -- Fetal imaging -- Vascular and interventional radiology -- Nuclear medicine -- Breast imaging -- Roentgen classics.
  • O'Brien, William T.
    Status: Not Checked OutLane Catalog Record
  • 2013 Wiley
    edited by John McLoughlin, Neil Burgess, Hanif Motiwala, Mark J. Speakman, Andrew Doble, John D. Kelly.
    Expert urologists give their personal insight into the best methods of overcoming a variety of scenarios that occur during urologic surgery, randing from how to best salvage specific difficult intra-operative problems, to simplifying complex procedures, or tips advising on how best to clarify diagnosis.
  • 2011 Karger
    volume editors, Christian Surber, Peter Elsner, and Miranda A. Farage.
    Mucosal membranes have unique anatomical and physiological properties -- differing from those of the keratinized epithelium -- which affect drug or chemical absorption. This makes the diagnosis and treatment of diseases of the mucosa a challenge to dermatologists as well as gynecologists, since many conditions are difficult to recognize and well-established principles of skin disease treatment do not apply to the mucosa. This volume is exclusively devoted to the mucosal membrane and delivers a better understanding of this distinctive area. Subsequently to introductory chapters on the morphology and physiology of the mucosa, the topical treatment of impaired mucosal membranes is discussed. A third section covers the wide spectrum of consumer products applied on mucosal surfaces. Finally, the safety of products for mucosal membranes is reviewed. Providing an excellent summary and review of the latest findings and topical applications, this book will be of great value to physicians and clinicians in dermatology or gynecology, pharmacists, scientists and toxicologists who are involved in the development of products for mucosal membranes.
  • v. 1, 1978.
    edited by I. Ronald Shenker.
    Status: Not Checked OutLane Catalog Record
  • v. 2-, 2005- Springer
    Bronner, Felix; Farach-Carson, Mary C.
  • 1980-
    edited by Rolla B. Hill and James A. Terzian.
    Status: Not Checked OutLane Catalog Record
  • v. 2, 1943.
    von Eduard Pernkopf ...
    Status: Not Checked OutLane Catalog Record
    Bd. 1. Allgemeines, Brust und Brustgliedmasse -- Bd. 2. Bauch, Becken und Beckengliedmasse.
  • 2012 ScienceDirect
    2012 ClinicalKey
    [edited by] David N. Herndon.
    A brief history of acute burn care management -- Teamwork for total burn care: Burn centers and multidisciplinary burn teams -- Epidemiological, demographic, and outcome characteristics of burn injury -- Prevention of burn injuries -- Burn management in disasters and humanitarian crises -- Care of outpatient burns -- Pre-hospital management, transportation and emergency care -- Pathophysiology of burn shock and burn edema -- Fluid resuscitation and early management -- Evaluation of the burn wound: Management decisions -- Enzymatic debridement of burn wounds -- Treatment of infection in burns -- Operative wound management -- Anesthesia for burned patients -- The skin bank -- Alternative wound coverings -- The role of alternative wound substitutes in major burn wounds and burn scar resurfacing -- The pathophysiology of inhalation injury -- Diagnosis and treatment of inhalation injury -- Respiratory care -- The systemic inflammatory response syndrome -- The immunological response and strategies for intervention -- Hematologic and hematopoietic response to burn injury -- Significance of the adrenal and sympathetic response to burn injury -- The hepatic response to thermal injury -- Effects of burn Injury on bone and mineral metabolism -- Vitamin and trace element homeostasis following severe burn injury -- Hypophosphatemia -- Nutritional support of the burned patient -- Modulation of the hypermetabolic response after burn injury -- Etiology and prevention of multisystem organ failure -- Renal failure in association with thermal injuries -- Critical care in the severely burned: Organ support and management of complications -- Burn nursing -- Special considerations of age: The pediatric burned patient -- Care of geriatric patients -- Surgical management of complications of burn injury -- Electrical injuries -- Electrical injury: Reconstructive problems -- Cold-induced injury: Frostbite -- Chemical burns -- Radiation injuries and vesicant burns -- Exfoliative diseases of the integument and soft tissue necrotizing infections -- The burn problem: A pathologist's perspective -- Molecular and cellular basis of hypertrophic scarring -- Pathophysiology of the burn scar -- Comprehensive rehabilitation of the burn patient -- Musculoskeletal changes secondary to thermal burns -- Mitigation of burn-induced hypermetabolic and catabolic response during convalescence -- Reconstruction of burn deformities: An overview -- The use of skin grafts, skin flaps and tissue expansion in burn deformity reconstruction -- Microvascular technique of composite tissue transfer -- Reconstruction of the head and neck -- Correction of burn alopecia -- Reconstruction of the burned breast -- Management of contractural deformities involving the shoulder (axilla), elbow, hip and knee joints in burned patients -- Care of a burned hand and reconstruction of the deformities -- Management of burn injuries of the perineum -- Reconstruction of burn deformities of the lower extremity -- The ethical dimension of burn care -- Intentional burn injuries -- Functional sequelae and disability assessment -- Cost-containment and outcome measures -- Management of pain and other discomforts in burned patients -- Psychiatric disorders associated with burn injury -- Psychosocial recovery and reintegration of patients with burn injuries.
  • 2013 Springer
    Karl Knahr, editor.
    Part I: Ceramic-on-Ceramic Articulations -- Technology and Handling of Ceramic Implants -- Long-Term Stability of Ceramic Composite in Total Hip Arthroplasty -- Ceramic-Ceramic Bearing in Difficult Hips (Primary and Revision) -- Alumina-on-Alumina Bearings in Hip Arthroplasty: What Every Surgeon Should Know -- Part II: Metal-on-Metal Articulations -- Metal-on-Metal Resurfacing and the Cost to the Nation: A Conservative Estimate of the Unexpected Costs Required to Implement the New Metal-on-Metal Follow-Up Programme in the UK -- A Clinicopathological Study of Metal-on-Metal Hips Revised for Suspected Adverse Reactions to Metal Debris -- Metal-on-Metal Bearings and Surgical Techniques in Active Patients with Severe Hip Deformity -- The Incidence of Pseudotumour in Metal-on-Metal Hip Resurfacing and the Results of a Screening Tool for Patient Recall -- Part III: Polyethylene - Standard and New Improvements -- New Polys and Large Heads: Clinical Aspects -- The Influence of Head Material on Polyethylene Wear -- Basic Science and Longtime Results of Different Polyethylene Articulations -- Part IV: Large Diameter Heads -- Head Size and Metal-on-Metal Bearings -- Aseptic Loosening of Metal-on-Metal (MOM) Total Hip Arthroplasties (THA) with Large-Diameter Heads -- Large Head Articulations: Benefits and Drawbacks -- Can the Increased Loosening Rate of the Modular-Neck Hip Systems Be Attributed to Geometric Design Parameters? An Alternative Approach Using Finite Element Analysis -- Fracture of the Titanium Neck in a Modular Femoral Component -- Part V: Clinical Aspects -- Wear of Hard-on-Hard Bearings in the Hip: The Influence of Loss of Conformity Under Edge Loading -- Considerations for the Use of Bearing Partners in Total Hip Arthroplasty -- Total Hip Arthroplasty Using a Short, Metaphyseal-Fitting Anatomic Cementless Femoral Component in Patients with Femoral Head Osteonecrosis Who Are Less than 30 Years Old -- Survival of Monoblock Acetabular Cups Versus an Uncemented Modular Cup Design: A Population-Based Study from the Swedish Hip Arthroplasty Register.
  • 2012 Springer
    Karl Knahr, editor.
    Introduction: Tribology of hip prostheses -- wear performance and reliability -- effect of materials and head size -- How to treat failures related to articulation. Polyethylene articulations: Oxidation prevention with vitamin E in a HXLPE isoelastic monoblock pressfit cup -- Preliminary results -- In-Vitro Wear Testing of Conventional vs. Sequentially Cross-Linked Polyethylene Liners in Combination with Different Ceramic Femoral Heads -- Characterization of Vitamin E-blended UHMWPE for higher in vivo performance in orthopaedic arthroplasty -- Long-term reduction of wear and osteolysis with crosslinked PE? 13-years follow-up of a prospectively randomized comparison with conventional PE. Metal articulations: Metal-on-metal bearings in hip surgery: The London Implant Retrieval Centre Experience -- Total Hip Arthroplasty with a large diameter metal-on-metal cup (Durom) and a standard stem -- Short term results -- Polyethylene wear in metal-backed cups -- A retrospective analysis of 200 uncemented metal-backed cups. Immunological adverse reaction associated with low carbide content metal-on-metal bearings in a contemporary cementless total hip arthroplasty. Ceramic articulations: Fracture and squeaking in ceramic-on-ceramic bearings -- is it really a concern?- Long term stability of ceramic composite in total hip arthroplasty -- Ceramic-on-ceramic bearings in hip arthroplasty: a clinical review. Miscellaneous: Study of a titanium dual mobility socket with a mean follow-up of 18 years -- ECIMATM for low wear, good mechanical properties and oxidation resistance of hip bearings.
  • 2015 Springer
    E. Carlos Rodríguez-Merchán, Sam Oussedik, editors.
    This book offers a comprehensive guide to total knee arthroplasty (TKA) that will assist in achieving excellent outcomes based on a sound understanding and technique. After an introductory section on the native knee that covers the anatomy, physiology, biomechanics, and patterns of disease, all aspects of primary knee arthroplasty are discussed in detail. Individual chapters are devoted to topics such as acute pain management, the role of technological aids, prosthetic kinematics, alignment targets, unicompartmental arthroplasty, patellar resurfacing, outcome measures, and cost-effectiveness. An extensive section explains the causes and management of potential complications, including aseptic failure, infections, and periprosthetic fracture. The surgical techniques appropriate for revision knee arthroplasty are described separately, and guidelines on how to deal with bone loss, instability, and extensor mechanism failure are provided. The authors are all respected experts from the United Kingdom, United States, Australia and Europe.
  • 2015 Springer
    Theofilos Karachalios, editor.
    1. A brief history of total knee arthroplasty -- 2. Kinematics of the natural and replaced knee -- 3. Long term survival of total knee arthroplasty. Lessons learned from the clinical outcome of old designs -- 4. Long term survival of total knee arthroplasty. Lessons learned from the clinical outcome of old designs. Second generation of implants and the total condylar TKA -- 5. Total knee arthroplasty. Evaluating outcomes -- 6. The long term outcome of total knee arthroplasty. The effect of age and diagnosis -- 7. Long term outcome of primary total knee arthroplasty. The effect of body weight and level of activity -- 8. Long term clinical outcome of total knee arthroplasty. The effect of the severity of deformity -- 9. Long term clinical outcome of total knee arthroplasty. The effect of surgeon training and experience -- 10. Long term clinical outcome of total knee arthroplasty. The effect of limp alignment, implant placement and stability as controlled by surgical technique -- 11. Long term results of total knee arthroplasty. The effect of surgical approach -- 12. Long term clinical outcome of total knee arthroplasty. The effect of posterior stabilized designs -- 13. Long term clinical outcome of total knee arthroplasty. The effect posterior cruciate retaining design -- 14. Rationale and long term outcome to rotating platform total knee replacement -- 15. Mid to long term clinical outcome of medial pivot designs -- 16. Long term clinical outcome of total knee arthroplasty. The effect of implant fixation (cementless) -- 17. Long term clinical outcome of total knee arthroplasty: the effect of polyethylene -- 18. Long term clinical outcome of total knee arthroplasty. Condylar constrained prostheses -- 19. Long term clinical outcome of total knee arthroplasty rotating hinge designs -- 20. Clinical outcome of total knee megaprosthesis replacement for bone tumors -- 21. Long term clinical outcome of total knee arthroplasty. The effect of patella resurfacing -- 22. Infected total knee arthroplasty. Basic science, mangement, and outcome -- 23. Short and mid term outcome of total knee arthroplasty. The effect of rahabilitation -- 24. Mid and long term functional outcome of total knee arthroplasty -- 25. Long term outcome of total knee arthroplasty. The effect of navigation -- 26. Quality of life and patient satisfaction after total knee arthroplasty using contemporary designs -- Index.
  • 2014 ClinicalKey
    Richard D. Scott.
    Posterior cruciate ligament retention versus substitution -- Mobile versus fixed bearings in total knee arthroplasty -- Primary total knee arthroplasty surgical technique -- Total knee arthroplasty in severe varus deformity -- Total knee arthroplasty in severe valgus deformity -- Patellofemoral complications associated with total knee arthroplasty -- Stiffness before and after total knee arthroplasty -- Flexion contracture associated with total knee arthroplasty -- Total knee arthroplasty after osteotomy -- Total knee arthroplasty in rheumatoid arthritis -- Bone stock deficiency in total knee arthroplasty -- Bilateral simultaneous total knee arthroplasty -- Sepsis and total knee arthroplasty -- Staying out and getting out of trouble during total knee arthroplasty -- Repeat operation after total knee arthroplasty -- Unicompartmental knee arthroplasty -- Unicompartmental knee arthroplasty technique -- Frequently asked questions concerning total knee arthroplasty.
  • 2009 ClinicalKey
    [edited by] Arlen D. Hanssen, W. Norman Scott.
    Unicompartmental Knee Arthroplasty -- Posterior Cruciate Ligament-Retaining Total Knee Arthroplasty -- Posterior-Stabilized Technique -- Methods of Rotational Alignment in Primary Total Knee Arthroplasty -- Valgus Total Knee Replacement -- Total Knee Replacement in the Varus Knee -- Tibial Component Alignment in Total Knee Arthroplasty: Intramedullary, Extramedullary, and Computer-Assisted Techniques -- Quadriceps-Sparing Total Knee Arthroplasty -- Minimally Invasive Total Knee Arthroplasty with Limited Medial Parapatellar Arthrotomy -- Minimally Invasive Subvastus Approach for Total Knee Arthroplasty -- Minimal Incision Total Knee Arthroplasty: the Mini-Midvastus Approach -- Monoblock Total Knee Arthroplasty -- Cementless Fixation -- Cemented Total Knee Arthroplasty -- Principles of Revision Total Knee Replacement -- Preoperative Planning for Revision Total Knee Replacement -- Surgical Exposures for Revision Total Knee Arthroplasty -- Soft Tissue Balancing in Revision Total Knee Arthroplasty -- Removing Well-Fixed Implants -- Revision of Failed Unicompartmental Knee Arthroplasty -- Cemented Stem Fixation in Revision Total Knee Arthroplasty -- Uncemented Stems in Revision Total Knee Arthroplasty -- PROSTALAC Articulating Spacer for Infected Total Knee Replacements -- Impaction Bone Grafting for Defects in Revision Total Knee Arthroplasty -- Treatment of Periprosthetic Femoral Fractures above a Total Knee Arthroplasty -- Knee Arthrodesis with an Intramedullary Nail After Failed Total Knee Arthroplasty -- Flexion and Extension Gap Balancing in Revision Total Knee Arthroplasty -- Extensor Mechanism Reconstruction in Total Knee Arthroplasty -- Metal Augments -- Metaphyseal Porous Metal Cones -- Structural Allografting -- Porous Tantalum for Patellar Reconstruction in Revision Total Knee Arthroplasty -- Cancellous Patellar Bone Grafting in Revision Total Knee Arthroplasty -- Hinged Total Knee Arthroplasty.
  • 2003 NLM
    prepared by Lori J. Klein, Jennifer R. Heiland, James S. Panagis.
    Assesses the current state of the science regarding primary and revision total knee replacements. References appear in 5 broad categories that parallel topics presented at the conference, with many of the topics further broken down. Citations may appear in only one category.
  • 2015 Springer
    Walter Siquini, editor ; in collaboration with Raffaella Ridolfo, Pierpaolo Stortoni, Emilio Feliciotti.
    Preface -- 1 Position of the patient -- 2 Steps shared by Total and Subtotal Gastrectomy -- 3 Total Gastrectomy -- 4 Manual Subtotal Gastrectomy.- 5 Stapled Subtotal Gastrectomy -- 6 Proximal Gastrectomy -- 7 Total and Subtotal D2 Laparoscopic Gastrectomy.- 8 Lymphadenectomy -- 9 Special Cases.
  • 2008 Springer
    Michael L. Lipton ; with a foreword by Emanuel Kanal.
    Part I. In the Beginning: Generating, Detecting, and Manipulating the MR (NMR) Signal -- Laying the Foundation: Nuclear Magnetism, Spin, and the NMR Phenomenon -- Rocking the Boat: Resonance, Excitation, and Relaxation -- Relaxation: What Happens Next? -- Image Contrast: T1, T2, T2*, and Proton Density -- Hardware, Especially Gradient Magnetic Fields -- Part II. User Friendly: Localizing and Optimizing the MRI Signal for Imaging -- Spatial Localization: Creating an Image -- Defining Image Size and Spatial Resolution -- Putting It All Together: An Introduction to Pulse Sequences -- Understanding, Assessing, and Maximizing Image Quality -- Artifacts: When Things Go Wrong, It's Not Necessarily All Bad -- Safety: First, Do No Harm -- Part III. To the Limit: Advanced MRI Applications -- Preparatory Modules: Saturation Techniques -- Readout Modules: Fast Imaging -- Volumetric Imaging: The Three-dimensional Fourier Transform -- Parallel Imaging: Acceleration with SENSE and SMASH -- Flow and Angiography: Artifacts and Imaging of Coherent Motion -- Diffusion: Detection of Microscopic Motion -- Understanding and Exploiting Magnetic Susceptibility -- Spectroscopy and Spectroscopic Imaging: In Vivo Chemical Assays by Exploiting the Chemical Shift.
  • 2012 Springer
    edited by Isidoro Di Carlo, Roberto Biffi ; foreword by John E. Niederhuber.
    Since their first application in 1982, Totally Implantable Venous Access Devices (TIVADs) have become increasingly important in the clinical practice, as more intensive chemotherapy and parenteral treatments have come into use. At this time, there is objective evidence that TIVADs are a safe, effective strategy for long-term venous access; they play a significant role throughout the management of the oncology patient, as they are needed in the initial phases for active treatments as well as in the last stages for palliative measures, making possible repeated administration of chemotherapeutic vesicant agents, nutrients, antibiotics, analgesics, and blood products. According to a number of prospective studies, use of TIVADs is associated with a significant complication rate (10% to 25% of all patients). Evidence-based data support that most complications are directly related to inappropriate technique of placement and/or nursing care, sometimes leading to TIVAD loss, significant morbidity, increased duration of hospitalization, and additional medical cost. A group of world-renowned experts - both in the clinical and research fields - contributed to this volume, whose aim is to provide clinicians, nurses and medical students with a multidisciplinary, full update on these devices, as long term central venous access can no be longer considered a routine matter, and serious complications can be maintained at a very low level only if strict adherence to a well-defined protocol of surgical technique and of catheter care is maintained.
  • 2012
    A. Schulze.
    Zur Entwicklung des nationalen Habitus in Deutschland -- Veränderungen des Verhaltens-, Gefühls- und Denkstandards von Ärzten -- Geschichte der Medizin anhand einiger ausgewählter Schwerpunkte -- Der unpolitische Arzt? -- Die satisfaktionsfähige Gesellschaft -- Militärmedizin im Ersten Weltkrieg -- Schubkraft von Kriegen -- Zur Geschichte der deutschen Psychiatrie -- Von der Entstehung der Eugenik als Wissenschaft zur Diskussion und Durchführung der Tötungen von Menschen -- Die Theorie Darwins und die Entwicklung sozial-darwinistischer Vorstellungen -- Auswirkungen der Darwinschen Theorie -- Vom Sozialdarwinismus zur Rassenhygiene -- Zur Entwicklung eugenischer Konzepte in Deutschland -- Ärzte helfen Hitler und der nationalsozialistischen Bewegung -- Die Freikorps : Wegbereiter Hitlers -- Vom heilenden zum tötenden Arzt : die Auflösung des Gewissens -- Die Ausschaltung jüdischer Ärzte -- Zwangssterilisationen -- Tötungen von Kindern -- Erwachsenentötungen -- Ärzte übernehmen direktes medizinisches Töten -- Selektion an der Rampe : Ärzte im Konzentrationslager -- Ärztliche Tätigkeiten in Konzentrationslagern -- Menschenversuche : Ärzte experimentieren am "Objekt Mensch -- Unterdruck- und Unterkühlungsversuche -- Versuche mit Fleckfieber-Impfstoff -- Hepatits Epidemica-Virus-Forschung -- Sulfonamid-, Knochentransplantations- und Phlegmonversuche -- Zwillingsforschung : das Kaiser Wilhelm-Institut für Anthropologie, menschliche Erblehre und Eugenik in Berlin Dahlem und das Konzentrationslager Auschwitz -- Der Prozess und die Urteile von Nürnberg -- Exkurs : nach 1945 -- Schlussbetrachtung -- Literaturverzeichnis.
  • 2013
    Andrew Koppelman.
    Introduction -- The road to the mandate -- Appropriate constitutional limits -- Bad news for mail robbers -- What the court did -- Where it hurts.
  • 2006 Ovid
    editors, John T. Walkup, Jonathan W. Mink, Peter J. Hollenbeck..
    Also available: Print – 2006
  • 2008 Springer
    edited by Rene V. Mayorga and Leonid Perlovsky.
  • 2011
    Catherine Elizabeth Chang.
    Functional magnetic resonance imaging (fMRI) based on blood-oxygen level dependent (BOLD) contrast is a powerful technique for non-invasive measurement of brain activity. Recent fMRI studies have revealed that the spontaneous BOLD fluctuations of the human brain organize into distributed, temporally-coherent networks ("resting-state networks"; RSNs). Examination of RSNs has yielded valuable insight into neural organization and development, and demonstrates potential as a biomarker for conditions such as Alzheimer's disease and depression. However, the accuracy by which the spatio-temporal properties of RSNs can be delineated using fMRI is compromised by the presence of physiological (cardiac and respiratory) noise and vascular hemodynamic variability. Further, our present understanding of how RSNs may interact and support cognitive function has been limited by the fact that the vast majority of studies to-date analyze RSNs in a manner that assumes temporal stationarity. Here, we describe efforts to correct for non-neural physiological influences on the BOLD signal, as well as investigations into the dynamic character of resting-state network connectivity. It is found that low-frequency variations in cardiac and respiratory processes account for significant noise across widespread gray matter regions, and that a constrained deconvolution approach may prove effective for modeling and reducing their effects. Application of the proposed noise-reduction procedure is observed to yield negative correlations between the spontaneous fluctuations of two major RSNs. The relationship between respiratory volume changes and the BOLD signal is further examined by simultaneously monitoring and comparing chest expansion data, end-tidal gas concentrations, and spontaneous BOLD fluctuations. The use of a breath-holding task is proposed for quantifying regional differences in BOLD signal timing that arise from local vasomotor response delays; such non-neural timing delays are found to impact inferences of resting-state connectivity and causality. Finally, a preliminary analysis of non-stationary connectivity between RSNs is performed using wavelet and sliding-window approaches, and it is observed that interactions between networks may reconfigure on time-scales of seconds to minutes.
  • 2011 NCBI Bookshelf
    Committee on a Framework for Developing a New Taxonomy of Disease, Board on Life Sciences, Division on Earth and Life Studies, National Research Council of the National Academies.
    "Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward precision medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward precision medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy."--Publisher's description.
  • 2014 Springer
    O.S. Miettinen.
    Scientific medicine in Miettinen's conception of it is very different from the two ideas about it that came to eminence in the 20th century. To him, medicine is scientific to the extent that it has a rational theoretical framework and a knowledge-base from medical science. He delineates the nature of that theoretical framework and of the research to develop the requisite knowledge for application in such a framework. The knowledge ultimately needed is about diagnostic, etiognostic, and prognostic probabilities, and it necessarily is to be codified in the form of probability functions, embedded in practice-guiding expert systems.
  • 2009 Springer
    Howard K. Koh, editor.
  • 2008
    Garrett Collins Heffner.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer
    Martine Derzelle.
    A rigorous and groundbreaking study. Martine Derzelle is the first researcher to approach hypochondria as a relational pathology. Martine Derzelle is the first researcher to approach hypochondria as a relational pathology. The author tackles a subject that has puzzled care professionals for decades: hypochondria. Martine Derzelle confronts all specialists (psychotherapists, psychiatrists, doctors, psychosomaticians) with the paradox of this pathology and the theoretical void on which the approach to those patients who express a suffering of various kinds has stood for more than a century. In the first part, the author highlights the lack of theoretical elaboration on hypochondria in the existent literature; in the second part, on the basis of clinical examples, she analyzes the nature of the disease, and then offers a completely innovative theoretical elaboration. Finally, in the third part, she proposes a new and specific approach to treating this pathology at both the theoretical and clinical levels within the framework of psychoanalysis and implementing key concepts from relational psychosomatics.
  • 2013 Springer
    L. Andrew Coward.
    The book explains how to understand cognition in terms of brain anatomy, physiology and chemistry, using an approach adapted from techniques for understanding complex electronic systems. These techniques create hierarchies of information process based descriptions on different levels of detail, where higher levels contain less information and can therefore describe complete cognitive phenomena, but are more approximate. The nature of the approximations are well understood, and more approximate higher level descriptions can therefore be mapped to more precise detailed descriptions of any part of a phenomenon as required. Cognitive phenomena, the anatomy and connectivity of major brain structures, neuron physiology, and cellular chemistry are reviewed. Various cognitive tasks are described in terms of information processes performed by different major anatomical structures. These higher level descriptions are selectively mapped to more detailed physiological and chemical levels.--[Source inconnue].
  • 2010 Springer
    Britt M. Glatzeder, Vinod Goel, Albrecht von Müller, editors.
    Part I. Perspectives on Thinking -- Problem Solving / Michael Öllinger and Vinod Goel -- Heuristic Bias, Conflict, and Rationality in Decision-Making / Wim De Neys -- Analogical Processes in Human Thinking and Learning / Dedre Gentner and Julie Colhoun -- A Gestalt Perspective on the Psychology of Thinking / Michael Wertheimer -- Thought and Reality: A Philosophical Conjecture About Some Fundamental Features of Human Thinking / Albrecht von Müller -- Part II. Components of Thinking -- Categorization and Object Shape / Markus Graf -- Comparison / Robert L. Goldstone, Sam Day, and Ji Y. Son -- Causal Thinking / Michael R. Waldmann -- Conditionals: Their Meaning and Their Use in Reasoning / Klaus Oberauer -- Thinking and Memory / Matthias Brand and Hans J. Markowitsch -- Perception and the Brain / Nikos Logothetis -- Part III. Onto- and Phylogenetic Considerations -- A Developmental Perspective on Modularity / Annette Karmiloff-Smith -- Theory of Mind / Beate Sodian and Susanne Kristen -- The Development of Metacognitive Competences / Wolfgang Schneider -- Understanding Apes to Understand Humans: The Case of Object-Object Relations / Josep Call -- Part IV. Language, Emotion, Culture -- Socializing Cognition / Anne Böckler, Günther Knoblich, and Natalie Sebanz -- Thinking and Language: A View from Cognitive Semio-Linguistics / Per Aage Brandt -- Thinking and Emotion: Affective Modulation of Cognitive Processing Modes / Annette Bolte and Thomas Goschke -- Cultural Differences in Thinking Styles / Shihui Han -- Part V. Modeling and Neurobiological Aspects -- Natural Selection in the Brain / Chrisantha Fernando and Eörs Szathmáry -- Value and Self-Referential Control: Necessary Ingredients for the Autonomous Development of Flexible Intelligence / Olaf Sporns and Edgar Körner -- Cortical Connectivity: The Infrastructure of Thoughts / Giorgio M. Innocenti -- Models as Tools to Aid Thinking / Helge Ritter.
  • 2012
    Paul Herag Nuyujukian.
    Neural prostheses translate signals from the brain into useful control signals, manipulating end-effectors such as computer cursors or robotic arms. Their aim is to offer greater interaction with the world for patients suffering from limb dysfunction due to spinal cord injury, neurodegenerative disease, and other conditions leading to limb paralysis. Prior intracortical electrode neural prosthesis studies have demonstrated compelling proof-of-concept systems, but barriers to successful clinical translation still remain, such as performance and robustness. Measures of performance include the speed, accuracy, and bitrate of the system. Robustness refers to the sustained performance of the system within a day and across days. The work presented here demonstrates algorithms and advances for neural prostheses that increase both performance and robustness. The recalibrated feedback intention trained Kalman filter (ReFIT-KF) increased performance by at least twofold compared to previously reported decoders, approaching the speed of natural arm movements. It achieved bitrates of up to 4.5 bits per second (bps) and communication rates of up to 10 words per minute (wpm) when used on a typing task. These results were reliable and repeatable for hours at a time across 4 array-years between two subjects. Utilizing neural spike threshold crossings as a signal source, the ReFIT-KF algorithm also demonstrated sustainable performance without any changes to decoder weights for one year with a degradation rate of 0.05 bps per month. Performance further increased when the ReFIT-KF was combined with an HMM state decoder for the detection of clicks, eliminating the need for hold periods. This combined ReFIT-KF and HMM decoder achieved bitrates of up to 6.5 bps and 15 wpm. Taken together, these findings may help advance neural prostheses closer to clinical viability.
  • 2010
    Vikash Gilja.
    By restoring the ability to move and communicate with the world, brain machine interfaces (BMIs) offer the potential to improve quality of life for people suffering from spinal cord injury, stroke, or neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS). BMIs attempt to translate measured neural signals into the user's intentions and, subsequently, control a computer or actuator. Recently, compelling examples of intra-cortical BMIs have been demonstrated in tetraplegic patients. Although these studies provide a powerful proof-of-concept, clinical viability is impeded by limited performance and robustness over short (hours) and long (days) timescales. We address performance and robustness over short time periods by approaching BMIs as a systems level design problem. We identify key components of the system and design a novel BMI from a feedback control perspective. In this perspective, the brain is the controller of a new plant, defined by the BMI, and the actions of this BMI are witnessed by the user. This simple perspective leads to design advances that result in significant qualitative and quantitative performance improvements. Through online closed loop experiments, we show that this BMI is capable of producing continuous endpoint movements that approach native limb performance and can operate continuously for hours. We also demonstrate how this system can be operated across days by a bootstrap procedure with the potential to eliminate an explicit recalibration step. To examine the use of BMIs over longer timescales, we develop new electrophysiology tools that allow for continuous multi-day neural recording. Through application of this technology, we measure the signal acquisition stability (and instability) of the electrode array technology used in current BMI clinical trials. We also demonstrate how these systems can be used to study BMI decoding over longer time periods. In this demonstration, we present a simple methodology for switching BMI systems on and off at appropriate times. The algorithms and methods demonstrated can be run with existing low power application specific integrated circuits (ASICs), with a defined path towards the development of a fully implantable neural interface system. We believe that these advances are a step towards clinical viability and, with careful user interface design, neural prosthetic systems can be translated into real world solutions.
  • 2010 Springer
    Jacob A. Belzen.
    This book takes a bold stand: all psychology should be culturally sensitive psychology, especially when studying religious phenomena. It explains that culture is not simply to be conceived of as a variable that possibly influences behavior. Rather, it stresses that cultural patterns of acting, thinking and experiencing are created, adopted and promulgated by a number of individuals jointly. As human subjectivity is different in different cultures, cultural psychology is not interested in comparatively investigating how experiences and behavior, attitudes and social relationships present themselves within different cultural conditions. By consequence, cultural psychology does not start from Western psychological constructs, testing for their presence in other cultures, but from human acts and activities in specific cultures, analyzing them in a hermeneutical way. Like cultural psychology, psychology of religion currently enjoys more and more interest and rapid growth. But the two fields have remained rather unconnected in the recent past. Psychological research on religion has been pursued from a number of perspectives, among which a cultural psychological one has not yet become prominent. As religions, however conceptualized, are cultural entities of major importance, cultural psychology seems a natural ally to research on religion. Containing a number of studies, both theoretical and empirical, this volume takes a step towards a rapprochement of cultural psychology and psychology of religion.
  • 2011
    Anna Petrovskaya.
    Reliable perception is required in order for robots to operate safely in unpredictable and complex human environments. However, reliability of perceptual inference algorithms has been poorly studied so far. These algorithms capture uncertain knowledge about the world in the form of probabilistic belief distributions. A number of Monte Carlo and deterministic approaches have been developed, but their efficiency depends on the degree of smoothness of the beliefs. In the real world, the smoothness assumption often fails, leading to unreliable perceptual inference results. Motivated by concrete robotics problems, we propose two novel perceptual inference algorithms that explicitly consider local non-smoothness of beliefs and adapt to it. Both of these algorithms fall into the category of iterative divide-and-conquer methods and hence scale logarithmically with desired accuracy. The first algorithm is termed Scaling Series. It is an iterative Monte Carlo technique coupled with annealing. Local non-smoothness is accounted for by sampling strategy and by annealing schedule. The second algorithm is termed GRAB, which stands for Guaranteed Recursive Adaptive Bounding. GRAB is an iterative adaptive grid algorithm, which relies on bounds. In this case, local non-smoothness is captured in terms of local bounds and grid resolution. Scaling Series works well for beliefs with sharp transitions, but without many discontinuities. GRAB is most appropriate for beliefs with many discontinuities. Both of these algorithms far outperform the prior art in terms of reliability, efficiency, and accuracy. GRAB is also able to guarantee that a quality approximation of the belief is produced. The proposed algorithms are evaluated on a diverse set of real robotics problems: tactile perception, autonomous driving, and mobile manipulation. In tactile perception, we localize objects in 3D starting with very high initial uncertainty and estimating all 6 degrees of freedom. The localization is performed based on tactile sensory data. Using Scaling Series, we obtain highly accurate and reliable results in under 1 second. Improved tactile object localization contributes to manufacturing applications, where tactile perception is widely used for workpiece localization. It also enables robotic applications in situations where vision can be obstructed, such as rescue robotics and underwater robotics. In autonomous driving, we detect and track vehicles in the vicinity of the robot based on 2D and 3D laser range finders. In addition to estimating position and velocity of vehicles, we also model and estimate their geometric shape. The geometric model leads to highly accurate estimates of pose and velocity for each vehicle. It also greatly simplifies association of data, which are often split up into separate clusters due to occlusion. The proposed Scaling Series algorithm greatly improves reliability and ensures that the problem is solved within tight real time constraints of autonomous driving. In mobile manipulation, we achieve highly accurate robot localization based on commonly used 2D laser range finders using the GRAB algorithm. We show that the high accuracy allows robots to navigate in tight spaces and manipulate objects without having to sense them directly. We demonstrate our approach on the example of simultaneous building navigation, door handle manipulation, and door opening. We also propose hybrid environment models, which combine high resolution polygons for objects of interest with low resolution occupancy grid representations for the rest of the environment. High accuracy indoor localization contributes directly to home/office mobile robotics as well as to future robotics applications in construction, inspection, and maintenance of buildings. Based on the success of the proposed perceptual inference algorithms in the concrete robotics problems, it is our hope that this thesis will serve as a starting point for further development of highly reliable perceptual inference methods.
  • 2008
    volume editors, Betty Dodet ... [et al.].
  • 2007
    Phil Brown.
    Foreword / Lois Gibbs -- Preface : Toxic exposures and the challenge of environmental health -- Acknowledgments -- List of abbreviations -- 1. Citizen-science alliances and health social movements : contested illnesses and challenges to the dominant epidemiological paradigm -- 2. Breast cancer : a powerful movement and a struggle for science -- 3. Asthma, environmental factors, and environmental justice -- 4. Gulf War-related illnesses and the hunt for causation : the "stress of war" versus the "dirty battlefield" -- 5. Similarities and differences among asthma, breast cancer, and Gulf War illnesses -- 6. The new precautionary approach : a public paradigm in progress -- 7. Implications of the contested illnesses perspective -- 8. Conclusion : the growing environmental health movement -- Notes -- Bibliography -- Index.
  • 2015 Springer
    José M. Fuentes, editor.
    Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
  • 2013 CRCnetBASE
    edited by Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, and Chirukandath Gopinath.
    Overview of drug development / James A. Popp and Jeffery A. Engelhardt -- Nonclinical safety evaluation of drugs / Thomas M. Monticello and Jeanine L. Bussiere -- Toxicokinetics and drug metabolism : relating toxicity to compound exposure and disposition / David D. Christ -- Introduction to toxicologic pathology / Judit E. Markovits ... [et al.] -- Routine and special techniques in toxicologic pathology / Daniel J. Patrick, Peter C. Mann -- Principles of clinical pathology / Robert L. Hall -- Toxicogenomics in toxicologic pathology / Mark J. Hoenerhoff and David E. Malarkey -- Spontaneous lesions in control animals used in toxicity studies / Robert C. Johnson, Robert H. Spaet, Daniel L. Potenta -- Gastrointestinal tract / Judit E. Markovits -- Liver, gall bladder, and exocrine pancreas / Russell C. Cattley, James A. Popp, Steven L. Vonderfecht -- Respiratory system / David J. Lewis and Tom P. McKevitt -- Urinary system / Kendall S. Frazier and John Curtis Seely -- Hematopoietic system / Kristin Henson, Glenn Elliott, Gregory S. Travlos -- The lymphoid system / Patrick J. Haley -- Bone, muscle, and tooth / John L. Vahle ... [et al.] -- The cardiovascular system / Calvert Louden, David Brott -- Endocrine glands / Sundeep Chandra, Mark Hoenerhoff, Richard Peterson -- Reproductive system and mammary gland / Justin D. Vidal ... [et al.] -- Skin / Zbigniew Wojcinski ... [et al.] -- Nervous system / Mark T. Butt, Robert Sills, Alys Bradley -- Special senses : eye and ear / James A. Render, Kenneth A. Schafer, Richard A. Altschuler.
  • 2007 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2007
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2004 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2004
  • 2004 ATSDR
    prepared by Syracuse Research Corporation under contract No. 205-1999-00024 ; prepared for U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2004
  • 2007 ATSDR
    prepared by Syracuse Research Corporation ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2007
  • 2007 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2007
  • 2007 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2007
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2004 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2004
  • 2004 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2004
  • 2006 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2006
  • 2006 ATSDR
    prepared by Syracuse Research Corporation under Contract No. 200-2004-09793; prepared for U.S. Deptartment of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2006
  • 2006
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for the U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Status: Not Checked OutLane Catalog Record
  • 2010 ATSDR
  • 2007 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2007
  • 2006 ATSDR
    prepared by Syracuse Research Corporation under contract No. 200-2004-09793 ; prepared for U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2006
  • 2007 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2007
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2008 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2008
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2006 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2006
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2006 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793; prepared for U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2006
  • 2007 ATSDR
    prepared by Syracuse Research Corporation under contract no. 200-2004-09793 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2007
  • 2005 ATSDR
    prepared by Syracuse Research Corporation under contract no. 205-1999-00024 ; prepared for U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry.
    Also available: Print – 2005
  • 2008 CRCnetBASE
    Elsa Nielsen, Grete stergaard, John Christian Larsen.
    International and federal bodies involved in risk assessment of chemical substances -- Data for hazard assessment -- Hazard assessment -- Standard setting : threshold effects -- Standard setting : non-threshold effects (carcinogenicity) -- Exposure assessment -- Risk characterization -- Regulatory standards set by various bodies -- Combined actions of chemicals in mixture.
  • v. <1>, <1978>
    Irving Sunshine, section editor.
    Status: Not Checked OutLane Catalog Record
  • 2005 CRCnetBASE
    edited by Shih-Houng Young and Vincent Castranova.
  • 2012 Knovel
    [edited by] Ken Donaldson... [et al.].
    "The widespread and increasing use of carbon nanotubes in scientific and engineering research and their incorporation into manufactured goods has urged an assessment of the risks and hazards associated with exposure to them. The field of nanotoxicology studies the toxicology of nanoparticles such as carbon nanotubes and has become a major growth area aimed towards risk assessment of nanoparticles. Compiled by a team of leading experts at the forefront of research, this is the first book dedicated to the toxicology of carbon nanotubes. It provides state-of-the-science information on how and why they are so potentially dangerous if breathed in, including their similarities to asbestos. The book examines various aspects of carbon nanotubes, from their manufacture and aerodynamic behaviour to their effects at molecular level in the lungs. It is invaluable to the many groups involved with research in this area, as well as to regulators and risk assessors"-- Provided by publisher.
  • 2007 CRCnetBASE
    edited by Yogesh C. Awasthi.
  • 2006 ScienceDirect
    edited by Ramesh C. Gupta.
  • 1974-
    Wayland J. Hayes, Jr.
    Status: Not Checked OutLane Catalog Record
  • 2007 CRCnetBASE
    edited by Shayne C. Gad.
    Introduction: the gastrointestinal (GI) tract as a barrier and as an absorptive and metabolic organ / Shayne C. Gad -- Methods for the analysis of gastrointestinal function / Robin C. Guy -- Safety pharmacology and the GI tract / Henry I. Jacoby -- Gastronintestinal tract development and its importance in toxicology / Joseph V. Rodricks, Allison A. Yates, and Claire L. Kruger -- The GI tract as major route of pharmaceutical administration / Robert W. Kapp, Jr. -- Gastrointestinal function and toxicology in canines / Charles Spainhour -- Absorption of macromolecules by mammalian intestinal epithelium / Shayne C. Gad -- Peyer's patch epithelium: an imperfect barrier / Gary R. Burleson and Florence G. Burleson -- Alteration of intestinal function by xenobiotic exposure: animal models / Shayne C. Gad -- Intestinal absorption and metabolism of xenobiotics in laboratory animals / William J. Brock -- Normal and abnormal intestinal absorption by humans / David W. Hobson and Valerie L. Hobson -- Intestinal absorption and metabolism of xenobiotics in humans / William J. Brock and David W. Hobson.
  • 2005 CRCnetBASE
    edited by Joan B. Tarloff, Lawrence H. Lash.
  • 2006 CRCnetBASE
    edited by Donald E. Gardner.
  • 2005 CRCnetBASE
    edited by Parviz M. Pour.
  • 2010 CRCnetBASE
    edited by Nancy A. Monteiro-Riviere.
    Pt. 1. Skin morphology and barrier properties -- pt. 2. Altered barriers -- pt. 3. Methods of delivery -- pt. 4. Skin toxicity.
  • v.1-2=, 2014 CRCnetBASE
    v.2 (2014) CRCnetBASE
    editor, Gian Paolo Rossini.
    Structured account of the existing knowledge of toxic algae, the chemistry of the toxins they produce, the effects these substances exert in humans and wildlife, as well as the strategies envisaged to protect public health and the environment. Covers recent advances in the understanding of the biology of toxin producers and the factors involved in the appearance and dynamics of harmful algae blooms, the factors affecting toxin production, the synthesis of toxins both in natural producers and by chemical means in a lab, and the toxin groups posing continuing and novel. Studies effects toxic microalgae and their poisonous products exert on living systems and how they may affect human activities.
  • 2010 Springer
    R. Manjunatha Kini, Kenneth J. Clemetso, Francis S. Markland, Mary Ann McLane, Takashi Morita, editors.
    "Circulation of blood is vital for the survival of vertebrates, including man. Mainly, it plays an important role in carrying food nutrients and oxygen to every tissue and organ and in removing all waste products and carbon dioxide. Any imbalance in the hemostatic and cardiovascular systems can lead to death and severe debility. A number of animals have developed mechanisms to target these systems and exploit the vulnerability. In some species (for example, snakes), such mechanisms are used to immobilize and kill the victim/prey, whereas in others (for example, insects, such as leaches, mosquitoes and ticks), they are used to provide a continuous supply of blood. These mechanisms include, but are not limited to, procoagulant and anticoagulant actions that affect the coagulation cascade and platelet aggregation, as well as altering vasodilatory responses. In all these various animals, these mechanisms have evolved to perfection over millions of years to support their survival. In last 3-4 decades, due to the efforts of scientists from various backgrounds including biology, protein chemistry, molecular biology, pharmacology, hematology, and structural biology, significant progress in understanding the structure-function relationships, as well as the mechanism of action have been made in a number of exogenous factors that affect blood coagulation, platelet aggregation and vasodilation from various animals. These exogenous factors have contributed significantly to the development of research tools as well as providing new therapeutic agents."
  • 2005 CRCnetBASE
    edited by Waldemar M. Dabrowski, Zdzislaw E. Sikorski.
  • 2014 ScienceDirect
    edited by Louis M. Weiss and Kami Kim.
    This book reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism.
  • 2010
    Yi-Ching Ong.
    Toxoplasma gondii is an obligate, intracellular parasite of the Apicomplexan phylum that is able to infect nearly all warm-blooded vertebrates. This capability for survival in a variety of host niches is reflected in the diversification of Toxoplasma strains. Strains differ dramatically in their interaction with hosts, and a fruitful approach towards understanding the molecular underpinnings of disease has been to identify and characterize drivers of strain-specific differences in host response. Chapter 1 provides a general introduction to Toxoplasma gondii and its ability to modulate host immunity, with special attention given to what is known about the mechanisms behind strain-specific phenotypes and the role of one particular player, ROP16. Chapter 2 describes experiments demonstrating that Toxoplasma secretes a polymorphic tyrosine kinase, ROP16, that can directly phosphorylate host STAT6. These experiments made use of a targeted disruption of the ROP16 locus in Type I parasites to identify ROP16-dependent signaling pathways, and used biochemical approaches to dissect the mechanism by which ROP16 is able to induce rapid STAT6 activation. Chapter 3 describes work demonstrating that ROP16 activation of STAT6 directs murine macrophage polarization towards an alternatively activated (M2) phenotype. In Chapter 4, the avian host response to Toxoplasma is examined to determine whether strain-specific differences in host response might be inverted in non-mammalian hosts. We show that strain-specific transcriptional host response, as well as transcriptional host response modulated by ROP16, appears very similar in chickens as in mice and humans. This suggests that variance between mammalian and avian host species in general may not be the source of selective pressure for the success of these common strains, or of ROP16's variability. Chapter 5 concludes with a discussion of future directions for further characterization of ROP16's role in modulating host response. We show that ROP16 interacts with host chromatin and suggest that investigation of ROP16's function in the host nucleus might yield further molecular insights as to how Toxoplasma is able to co-opt host cells and influence the course of infection.
  • v. 1-5, 7-<9>, 1904/14-1937/46, 1954/57, 1960-65, <1965-1967>
    [Letizia Vaccari, recopiladora].
    Status: Not Checked OutLane Catalog Record
    Tomo I. 1904-1914 -- Tomo II. 1915-1923 -- Tomo III. 1923-1930 -- Tomo IV. 1931-1936 -- Tomo V. 1937-1946 -- Tomo VII. 1954-1957 -- Tomo VIII. 1960-1965 -- Tomo IX. 1965-1967.
  • 2013
    Feng Chen.
    While there has been great progress in identifying stem and progenitor cells and the signals that control their proliferation and differentiation, how stem/progenitor cells exit their niche and how they form new tissue is not well understood. Unlike in the embryo, tissue formation in an adult animal faces new challenges such as longer distances to migrate and a complex milieu of differentiated tissue to migrate around and/or coordinate with. To restore function to a tissue, stem/progenitor cells must also integrate into healthy tissue and coordinate growth with decaying tissue. In this thesis, I examine how tracheal progenitor cells exit their niche to form tracheal tissue during Drosophila melanogaster metamorphosis. Tracheal progenitors exit the niche in two waves. During the first wave, progenitors migrate onto the basal surface of larval tracheal branches destined for destruction, and track along the decaying branches. Progenitor outgrowth requires the embryonic tracheal branch inducer, Breathless FGFR, and surprisingly, the Branchless FGF ligand is expressed in larval branches along which progenitors crawl. In this way, outgrowth is coordinated with tissue decay. Progenitors that remain within the niche during the first wave exit later. However, instead of moving onto the basal surface of larval branches, progenitors exiting the niche during this second wave move along the apical surface, displacing larval cells, and repopulating the tracheal branch. This latter process does not resemble branching morphogenesis in the embryo and does not require Bnl/Btl FGF signaling, demonstrating that progenitor outgrowth does not always require embryonic guidance cues.
  • 2008
    [edited by] Eugene N. Myers, Jonas T. Johnson.
    Status: Not Checked OutLane Catalog Record
    The history of tracheotomy and intubation / Steven M. Zeitels ... [et al.] -- Alternatives to tracheostomy / Andrew Herlich -- Technique and complications of tracheostomy in adults / Rohan R. Walvekar and Eugene N. Myers -- Technique and complications of tracheostomy in the pediatric age group / Robert F. Yellon -- Tracheostomy in the intensive care unit setting / K. Kost -- Selecting a tracheostomy tube: current options / Carl-Eric Lindholm -- Tracheostomy in burn patients / H. Slater -- Tracheostomy in patients with the obstructive sleep apnea syndrome / Jonas T. Johnson -- Nursing management of the patient with a tracheostomy / Marilyn Hudak and Margaret Hickey -- Long-term care of patients with a tracheostomy / David A. Nace and Andrea R. Fox -- Communication options for tracheostomy and ventilator-dependent patients / Marta S. Kazandjian and Karen J. Dikeman -- Management of swallowing disorders in the patient with a tracheostomy / R.L. Carrau and T. Wasserman-Wincko.
  • 2010
    John E. Wennberg.
    Status: Not Checked OutLane Catalog Record
    In health care, geography is destiny -- The Vermont experience -- Tonsillectomy and medical opinion -- Interpreting the pattern of surgical variation -- Understanding the market for preference-sensitive surgery -- Learning what works and what patients want -- The birth and near death of comparative effectiveness research -- Understanding supply-sensitive care -- Chronic illness and practice variation -- Is more better? -- Are America's "best hospitals" really the best? -- Ten top reasons why we need to reform the way we manage chronic illness -- Promoting organized care and reducing overuse -- Establishing shared decision making and informed patient choice -- Six ways to control costs, and accelerate health care reform -- The challenge of practice variations.
  • 2015 WHO
    This report is the first of its kind to measure health service coverage and financial protection to assess countries' progress towards universal health coverage. It shows that at least 400 million people do not have access to one or more essential health services and 6% of people in low- and middle-income countries are tipped into or pushed further into extreme poverty because of health spending.--Publisher description.
    Also available: Print – 2015
  • 2013 Cambridge
    edited by James David Adams, Jr, School of Pharmacy, University of Southern California, Los Angeles, CA, USA, Eric J. Lien, School of Pharmacy, University of Southern California, Los Angeles, CA, USA.
    The traditional and scientific bases for traditional Chinese medicine : communication between traditional practitioners, physicians and scientists / James D. Adams, Jr. and Eric J. Lien -- Structure-activity relationship analysis of plant-derived compounds / Eric J. Lien, Linda L. Lien and James D. Adams -- Huang Di Nei Jing and the treatment of low back pain / Minchen Wang (Vince) -- Understanding ch'i : the life-force energy that determines vitality, health and wellbeing / Marcia R. Babcock -- When modern computational systems biology meets traditional Chinese medicine / Calvin Yu-Chian Chen -- Modern drug discovery from Chinese materia medica used in traditional Chinese medicine / Kuo-Hsiung Lee, Susan L. Morris-Natschke, Joshua Brattlie, Jingxi Xie and Eileen Belding -- PI3K-AKT signaling in cell growth and metabolism / Yang Li, Anketse Kassa and Bangyan L. Stiles -- The scientific evidence for using astragalus in human diseases / William C.S. Cho -- Traditional Chinese medicine : anti-inflammation for cancer prevention / Constance L. L. Saw, Chee L. Saw and Lita S.T. Chew -- Treatment of stroke with Dan Shen, Salvia miltiorrhiza / James David Adams, Jr. -- Drug discovery from traditional Chinese medicine for neurogenesis : implications for stroke and neurodegenerative diseases / Jiangang Shen and Xingmiao Chen -- Medicinal uses of seaweed in traditional Chinese medicine / Eri Oshima -- The preventive effect of traditional Chinese medicinal herbs on type 2 Diabetes mellitus / Zhijun Wang, Patrick Chan and Jeffrey Wang -- Translational approach to treating diabetes using acupuncture or electroacupuncture / Philip V. Peplow and G. David Baxter.
  • v. 1-, 2002- CRCnetBase
  • 2006 CRCnetBASE
    edited by Amala Soumyanath.
  • 2010 Springer
    Laura Piccardi ... [et al.].
  • 2015 Springer
    Nader Francis, Abe Fingerhut, Roberto Bergamaschi, Roger Motson, editors.
    1. Learning environment and setting up a training unit in Minimal Access Surgery -- 2. Training curriculum in Minimal Access Surgery -- 3. Simulation and Training in Minimal Access Surgery -- 4. Training basic laparoscopic skills -- 5. Training for trainers in Endoscopy (colonoscopy) -- 6. Teaching advanced laparoscopic skills in colorectal surgery -- 7. Teaching advanced laparoscopic skills in surgery for morbid obesity -- 8. Teaching advanced laparoscopic skills in urological surgery -- 9. Training for new thechniques and robotic surgery in Minimal Access Surgery -- 10. Teletraining in Minimal Access Surgery -- 11. Assessment and Acreditation in Minimal Access Surgery -- 12. Training the trainer in laparoscopic surgery -- 13. The Human Factor in Minimal Access Surgical Training: How conscientious, well trained Surgeons make mistakes.
  • v. 1, 1889.
    par L. Testut, professeur d'anatomie à la Faculté de Médecine de Lyon ; avec la collaboration pour l'histologie et l'embryologie de mm. G. Ferré, professeur agrégé à la Faculté de Médecine de Bordeaux, et L. Vialleton, chef des travaux histologiques à la Faculté de Médecine de Lyon.
    Status: Not Checked OutLane Catalog Record
    t. 1. Ostéologie. Arthrologie. Myologie -- t. 2. Angéilogie. Système nerveux central -- t. 3. Système nerveux périphérique. Organes des sens -- t. 4. Appareil de la digestion. Appareil de la respiration et de la phonation. Appareil uro-génital. Embryologie.
  • v. 1-2. Google Books
    Fulltext (v.2) Google Books
    Tillaux, P.
    Also available: Print – v. 1-2., 1877-
  • Google Books
    par MM. J. Babinski, Gilbert Ballet, P. Blocq, E. Boix, H. Dutil, H. Grenet, Hallion, H. Lamy, Ch. Laubry, H. Meige, Rogues de Fursac, A. Souques ; avec figures dans le texte.
    Also available: Print – v. 10., 1899-
  • 2009 Springer
    coordinateurs, Xavier Hébuterne ... [et al.].
  • v. 1-3, 1911-15. Google Books
    Fulltext (v.2 1911) Google Books
    Fulltext (v.3 1912) Google Books
    Grasset, J.; Rimbaud, Louis.
    [t.] 1. Fonctions de réception, absorption, circulation, elaboration et élimination de la matière: trophobiologie (Deuxième édition revue et autmentée par le docteur Rimbaud. 1915. [8], 1,059 p. incl. XXXIII tables, 1 diagr.) -- 2. Fonctions de défense contre la maladie: antixénisme (1911. [6], 1,010 p. 2 fold. tables) -- 3. Fonctions de réception, élaboration et émission de l'énergie, neurobiologie: fonctions de reproduction: ontogénie et phylogénie, hérédité (1912. [6], 1,176 p. incl. 37 ill, XXXII tables).
  • v. 1, 4, 1964-.
    publié sous la direction du J. Senèque, par J.P. Binet ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • Google Books
    Gérard, Ernest.
    Also available: Print – 1907.
  • Google Books
    par F. Viault [et] F. Jolyet.
    Also available: Print – 1894.
  • Google Books
    par A. d'Espine [et] C. Picot.
    Also available: Print – 1899
  • Google Books
    Clerc, F.-F.
    Also available: Print – 1866-
  • Google Books
    Rédigées, et précédées de l'anatomie et de la physiologie de la peau par E. Gaucher.
    Contents -- t. 1, fasc. 1. Anatomie et physiologie. Pathologie générale. fasc. 2. Dermatoses inflammatoires communes.
    Also available: Print – v. 1, 1881-85.
  • Google Books
    par R. Leriche.
    t. 1. Fractures articulaires.
    Also available: Print – v. 1, 1917.
  • 2005 CRCnetBASE
    editors, Dharma R. Kodali, Gary R. List.
  • 1959
    edited by A.B. Wallace.
    Status: Not Checked OutLane Catalog Record
  • 2005 Springer
    Corrado Priami, Emanuela Merelli, Pedro Pablo Gonzalez, Andrea Omicini (eds.).
  • 2006 Springer
    Corrado Priami, Luca Cardelli, Stephen Emmott (eds.).
    Scientific Foundation for Global Computing / Robin Milner -- Interdisciplinary Innovation in International Initiatives / John C. Wooley -- A Grand Challenge for Converging Sciences / Ronan Sleep -- Applying Computer Science Research to Biodiversity Informatics: Some Experiences and Lessons / Andrew C. Jones -- e-Science and the VL-e Approach / L.O. (Bob) Hertzberger -- From Syntax to Semantics in Systems Biology Towards Automated Reasoning Tools / François Fages -- SYMBIONIC: A European Initiative on the Systems Biology of the Neuronal Cell / Ivan Arisi, Paola Roncaglia, Vittorio Rosato, Antonino Cattaneo -- A Biological Approach to Autonomic Communication Systems / Iacopo Carreras, Imrich Chlamtac, Francesco De Pellegrini, Csaba Kiraly, Daniele Miorandi, Hagen Woesner -- The Twilight of the Despotic Digital Civilization / Michel Riguidel -- A Compositional Approach to the Stochastic Dynamics of Gene Networks / Ralf Blossey, Luca Cardelli, Andrew Phillips -- A Weighted Profile Based Method for Protein-RNA Interacting Residue Prediction / Euna Jeong, Satoru Miyano.
  • 2006 Springer
    Corrado Priami, Xiaohua Hu, Yi Pan, Tsau Young Lin (eds.).
  • 2006 Springer
    Corrado Priami, Gordon Plotkin (eds.).
  • 2014 Springer
    Marcin Zielinski, Ramón Rami-Porta, editors.
    Use of the transcervical approach in thoracic surgery has advanced significantly during the past 60 years, owing primarily to advances in technology. Nevertheless, the possibilities of this approach have never been compiled in a systematic way. This book aims to rectify the situation by describing, in a structured way, all the thoracic procedures that can be performed using the transcervical approach. Indications and contraindications, surgical techniques, complications, and results are all covered, based on the authors' experience and published reports. The contents encompass diverse surgical endoscopic procedures for diagnosis and staging, use of the transcervical approach for surgery to the thymus and mediastinum, lungs and bronchi, trachea, and esophagus, and miscellaneous items including the role of robotic surgery.
  • 2007 Karger
    volume editors, M.A. Marcolin, F. Padberg.
    Electroconvulsive therapy : update and new research / Eser, D. ... [et al.] -- Repetitive transcranial magnetic stimulation effects in vitro and in animal models / Keck, M.E. -- Neuroimaging of repetitive transcranial magnetic stimulation effects on the brain / George, M.S. ... [et al.] -- Efficacy and safety of prefrontal repetitive transcranial magnetic stimulation in affective disorders / Padberg, F. ... [et al.] -- Repetitive transcranial magnetic stimulation in augmentation of antidepressant drugs / Ortega Rumi, D.O. ... [et al.] -- Transcranial magnetic stimulation versus electroconvulsive therapy for the treatment of more severe major depression / Janicak, P.G. ... [et al.] -- Transcranial magnetic stimulation in schizophrenia / Odebrecht Rosa, M. ... [et al.] -- Repetitive transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder and other anxiety disorders / Pridmore, S., Marcolin, M.A., Mansur, C.G. -- Repetitive transcranial magnetic stimulation in non-psychiatric disorders : pain, Parkinson's disease, stroke, tinnitus / Lefaucheur, J.-P, Khedr, E.M. -- Induction and modulation of neuroplasticity by transcranial direct current stimulation / Nitsche, M.A. ... [et al.] -- Magnetic seizure therapy for the treatment of depression / Lisanby, S.H., Peterchev, A. -- Theta burst stimulation / Huang, Y.-Z., Rothwell, J.C. -- Transcranial magnetic stimulation of deep brain regions : principles and methods / Roth, Y., Padberg, F., Zangen, A.
  • 2014 Springer Protocols
    edited by Alexander Rotenberg, Jared Cooney Horvath, Alvaro Pascual-Leone.
    Transcranial magnetic stimulation (TMS) device and foundational techniques / Alexander Rotenberg, Jared Cooney Horvath, and Alvaro Pascual-Leone -- Transcranial magnetic stimulation (TMS) safety considerations and recommendations / Umer Najib and Jared Cooney Horvath -- Neuronavigation for transcranial magnetic stimulation / Roch Comeau -- Reaching deep brain structures : the h-coils / Yiftach Roth and Abraham Zangen -- Single-pulse transcranial magnetic stimulation (TMS) protocols and outcome measures / Faranak Farzan -- Paired-pulse transcranial magnetic stimulation (TMS) protocols / Andrew Vahabzadeh-Hagh -- Repetitive transcranial magnetic stimulation (rTMS) protocols / Lindsay Oberman -- Offline and online "Virtual Lesion" protocols / Shirley Fecteau and Mark Eldaief -- State-dependent transcranial magnetic stimulation (TMS) protocols / Juha Silvanto and Zaira Cattaneo -- Combination of transcranial magnetic stimulation (TMS) with functional magnetic resonance imaging / Joan A. Camprodon and Mark A. Halko -- Electroencephalography during transcranial magnetic stimulation : current modus operandi / Marine Vernet and Gregor Thut -- Transcranial magnetic stimulation (TMS) clinical applications : therapeutics / Jared Cooney Horvath, Umer Najib, and Daniel Press -- Transcranial magnetic stimulation (TMS) clinical applications : diagnostics / Josep Valls-Sole -- Review of current clinical practice in the treatment of major depression / Mark A. Demitrack and David G. Brock -- Protocol for depression treatment utilizing h-coil deep brain stimulation / Yiftach Roth and Abraham Zangen -- Navigated transcranial magnetic stimulation : principles and protocol for mapping the motor cortex / Jari Karhu, Henri Hannula, Jarmo Laine, and Jarmo Ruohonen -- Speech mapping with transcranial magnetic stimulation / Phiroz E. Tarapore.
  • 2014 Springer Protocols
    edited by Etsuko Miyamoto-Sato [and four others].
  • 2010 Springer Protocols
    edited by Paul J. Higgins.
    A review of post-translational modifications and subcellular localization of Ets transcription factors : possible connection with cancer and involvement in the hypoxic response / Céline Charlot ... [et al.] -- Regulation of transcription factor function by targeted protein degradation : an overview focusing on p53, c-Myc, and c-Jun / Jukka Westermarck -- Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents / Aldo Giudice, Claudio Arra, and Maria C. Turco -- Subnuclear localization and intranuclear trafficking of transcription factors / Sayyed K. Zaidi ... [et al.] -- Analysis of ligand-dependent nuclear accumulation of Smads in TGF-[beta] signaling / Douglas A. Chapnick and Xuedong Liu -- Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1 / Richard Y.M. Ma ... [et al.] -- Coupling of dephosphorylation and nuclear export of Smads in TGF-[beta] signaling / Fangyan Dai ... [et al.] -- Assessing sequence-specific DNA binding and transcriptional activity of STAT1 transcription factor / Thomas Meyer and Uwe Vinkemeier -- Analysis of nuclear export using photoactivatable GFP fusion proteins and interspecies heterokaryons / Kerry-Ann Nakrieko, Iordanka A. Ivanova, and Lina Dagnino -- Determination of nuclear localization signal sequences for Krüppel-like factor 8 / Tina S. Mehta, Farah Monzur, and Jihe Zhao -- Methods to measure nuclear export of [beta]-catenin using fixed and live cell assays / Manisha Sharma and Beric R. Henderson -- Imaging of transcription factor trafficking in living cells : lessons from corticosteroid receptor dynamics / Mayumi Nishi -- Hypoxia-inducible factors : post-translational crosstalk of signaling pathways / Elitsa Y. Dimova and Thomas Kietzmann -- The basic helix-loop-helix-leucine zipper gene Mitf : analysis of alternative promoter choice and splicing / Kapil Bharti ... [et al.] -- Phosphorylation control of nuclear receptors / Sébastien Lalevée, Christine Ferry, and Cécile Rochette-Egly -- Regulation of Krüpple-like [i.e. Krüppel-like] factor 5 by targeted protein degradation / Ceshi Chen -- Post-translational control of ETS transcription factors : detection of modified factors at target gene promoters / Li Li, Janice Saxton, and Peter E. Shaw -- Integration of protein kinases into transcription complexes : identifying components of immobilised in vitro pre-initiation complexes / Hong-Mei Zhang ... [et al.] -- Post-translational modification of p53 by ubiquitin / Chunhong Yan -- Phosphorylation-dependent regulation of SATB1, the higher-order chromatin organizer and global gene regulator / Dimple Notani ... [et al.] -- In vivo and in vitro tools to identify and study transcriptional regulation of USF-1 target genes / Marie-Dominique Galibert and Sébastien Corre -- Measuring the absolute abundance of the Smad transcription factors using quantitative immunoblotting / David C. Clarke and Xuedong Liu -- Flow cytometry analysis of transcription factors in T lymphocytes / Diana I. Albu, Danielle Califano, and Dorina Avram -- Identification of specific protein/E-box-containing DNA complexes : lessons from the ubiquitously expressed USF transcription factors of the b-HLH-LZ super family / Marie-Dominique Galibert and Yorann Baron.
  • 2013 Springer
    Gary Hime, Helen Abud, editors.
    1. The Stem cell state / Gary R. Hime, Helen E. Abud -- 2. Induction of pluripotency / Corey Heffernan, Jun Liu, Huseyin Sumer -- pt. I. Model stem cell systems (A): invertebrate -- 3. Germline stem cells and their regulation in the nematode Caenorhabditis elegans / Aaron Kershner, Sarah L. Crittenden, Kyle Friend, Erika B. Sorensen, Douglas F. Porter -- 4.Transcriptional and post-transcriptional regulation of Drosophila germline stem cells and their differentiating progeny / Helen White-Cooper, Simona Caporilli -- 5. Stem cells in the Drosophila digestive system / Xiankun Zeng, Chhavi Chauhan, Steven X. Hou -- 6. Mechanisms of asymmetric progenitor divisions in the Drosophila central nervous system / Rita Sousa-Nunes, W. Gregory Somers -- pt. II. Model stem cell systems (B): vertebrate -- 7. Transcriptional/translational regulation of mammalian spermatogenic stem cells / Cathryn A. Hogarth -- 8. Transcriptional regulation and specification of neural stem cells / Kimberly J. Christie, Ben Emery, Mark Denham, Helena Bujalka, Holly S. Cate -- 9. Transcriptional control of epidermal stem cells / Briana Lee, Xing Dai -- 10. Regulation of intestinal stem cells by WNT and notch signalling / Katja Horvay, Helen E. Abud -- 11. Transcriptional regulation of haematopoietic stem cells / Adam C. Wilkinson, Berthold Göttgens -- 12. The Regulation of mesenchymal stem cell differentiation / David Cook, Paul Genever -- pt. III. Molecular families implicated in stem cell regulation -- 13. The Musashi family of RNA binding proteins: master regulators of multiple stem cell populations / Jessie M. Sutherland, Eileen A. McLaughlin, Gary R. Hime, Nicole A. Siddall -- 14. JAK-STAT signaling in stem cells / Rachel R. Stine, Erika L. Matunis -- 15. Myc in stem cell behaviour: insights from Drosophila / Leonie M. Quinn, Julie Secombe, Gary R. Hime -- 16. The Role of nuclear receptors in embryonic stem cells / Qin Wang, Austin J. Cooney -- 17. Epigenetic regulation of stem cells / Anton Wutz -- 18. Regulation of stem cell populations by microRNAs / Julie Mathieu, Hannele Ruohola-Baker -- 19. Myb and the regulation of stem cells in the intestine and brain: a tale of two niches / Jordane Malaterre, Lloyd Pereira, Robert G. Ramsay.
    Also available: Print – 2013
  • 2014 Springer
    Wilfried Ellmeier, Ichiro Taniuchi, editors.
    Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during Th differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity, and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.
  • 2007
    Jacob Michael Zahn.
    Status: Not Checked OutLane Catalog Record
  • 2012
    Regina Kar Wuen Cheung.
    Plasmacytoid dendritic cells (pDCs) are a rare subset of immune cells characterized by their ability to secrete large amounts of interferon alpha (IFN[alpha]) in response to Toll Like Receptor (TLR) activation by viral and endogenous nucleic acids. In these studies, we developed novel techniques that fundamentally change how cellular biologists can detect and assess protein and gene expression in cells based on function instead of phenotype. These techniques, which allow for transcript profiling of cells sorted by intracellular cytokine staining, and high throughput single cell detection of RNA transcript, were used to examine the role of pDC subsets that differ by IFN[alpha] and TNF secretion. Transcript profiling of these subsets revealed that after activation, there are two subsets of pDCs; cytokine secreting pDCs which express inflammatory and tolerogenic mediators, and quiescent noncytokine secreting pDCs, which maintain mRNA profile of unstimulated pDCs. Single cell RNAflow demonstrated that gene expression in subsets of pDCs from FLT3L DC (FLDC) cultures, bone marrow, and spleen correlates with cytokine staining. From our transcript profile data, we generated a list of candidate surface markers for cytokine secreting pDCs, which we screened by CyTOF and present here. Finally, we performed functional analysis of CD4- and CD4+ pDC subsets, and demonstrated that CD4- pDCs contain more activateable pDCs which take up antigen and induce antigen specific T cell proliferation. Taken together, these studies suggest that upon TLR activation, concomitant expression of rate limiting signaling genes leads to stochastic pDC expression of IFN[alpha] and TNF, leaving a larger pool of non cytokine secreting pDCs that maintain their pDC phenotype and expression pattern, and which may be activated at a later time. These studies also demonstrate the utility of screening based on function (cytokine secretion) instead of phenotype, which in this case, allowed for more complete assessment of variation between cells of different function.
  • edited by Steven L. McKnight and Keith R. Yamamoto.
  • 2008 Springer
    Serena M. Dudek, editor.
  • 2009
    Michael F. Carey, Craig L. Peterson, Stephen T. Smale.
    Status: Not Checked OutLane Catalog Record
  • 2012 Springer Protocols
    edited by Ales Vancura.
    Genome-wide in vivo cross-linking of sequence-specific transcription factors / Xiao-Yong li and Mark D. Biggin -- Characterization of complex regulatory networks and identification of promoter regulatory elements in yeast : "in silico" And "wet-lab" approaches / Nuno P. Mira, Miguel C. Teixeira, and Isabel Sá-Correia -- Electrophoretic mobility shift assay analysis of NF[kappa]B transcriptional regulation by nuclear I[kappa]B[alpha] / Ashish Juvekar [and others] -- Probing endogenous RNA polymerase II pre-initiation complexes by electrophoretic mobility shift assay / Emmanuelle Wilhelm, Christopher Takacs, and Brendan Bell -- Elucidating protein : DNA complex by oligonucleotide DNA affinity purification / Teddy T.C. Yang and Chi-Wing Chow -- Chromatin immunoprecipitation assay as a tool for analyzing transcription factor activity / Padmaja Gade and Dhan V. Kalvakolanu -- Two-step cross-linking for analysis of protein-chromatin interactions / Bing Tian, Jun Yan, and Allan R. Brasier -- Chromatin immunoprecipitation analysis of NF[kappa]B transcriptional regulation by nuclear I[kappa]B[alpha] in human macrophages / Sitharam Ramaswami [and others] -- In vivo ChIP for the analysis of microdissected tissue samples / Chris Murgatroyd, Anke Hoffmann, and Dietmar Spengler -- Quantification of protein-DNA interactions by in vivo chromatin immunoprecipitation in yeast / Amparo Pascual-Ahuir and Markus Proft -- Mapping protein-DNA interactions using ChIP-sequencing / Charles E. Massie and Ian G. Mils -- ChIP and re-ChIP assays : investigating interactions between regulatory proteins, histone modifications, and the DNA sequences to which they bind / Agnieszka D. Truax and Susanna F. Greer -- Transcriptional regulation of genes via hypoxia-inducible factor / Olga Roche and Michael Ohh -- Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter / William A. Sands [and others] -- Computational analysis of promoter elements and chromatin features in yeast / John J. Wyrick -- Chromatin affinity purification / Ryoko Harada and Alain Nepveu -- Determination of histone acetylation status by chromatin immunoprecipitation / Luciano Galdieri, John Moon, and Ales Vancura -- Immunostaining of Drosophila polytene chromosomes to investigate recruitment of chromatin-binding proteins / Magdalena Murawska and Alexander Brehm -- Detection of transcriptional activators, co-activators, and chromatin remodeling by chromatin immunoprecipitation coupled with real-time PCR / Tamara Y. Erkina and Alexandre M. Erkine -- Chromatin endogenous cleavage and psoralen crosslinking assays to analyze rRNA gene chromatin in vivo / Joachim Griesenbeck [and others] -- UV-induced DNA damage and DNA repair in ribosomal genes chromatin / Julie Pelloux [and others] -- Analysis of SUC2 promoter structure by nucleosome scanning / Jennifer Chang and Ales Vancura -- Chromatin immunoprecipitation of mouse embryos / Anne K. Voss [and others] -- Chromatin immunoprecipitation in mouse hippocampal cells and tissues / Badi Sri Sailaja, Takumi Takizawa, and Eran Meshorer -- Approaches for studying nucleosome movement by ATP-dependent chromatin remodeling complexes / Swetansu K. Hota and Blaine Bartholomew -- Mapping protein-DNA and protein-protein interactions of ATP-dependent chromatin remodelers / Swetansu K. Hota [and others] -- Evaluation of histone-modifying enzymes in stem cell populations / Leanne Stalker and Christopher Wynder -- Purification of multiprotein histone acetyltransferase complexes / Yuan-Liang Wang, Francesco Faiola, and Ernest Martinez -- Reconstitution of active and stoichiometric multisubunit lysine acetyltransferase complexes in insect cells / Kezhi Yan [and others] -- Affinity purification of MLL3/MLL4 histone H3K4 methyltransferase complex / Young-Wook Cho, SunHwa Hong, and Kai Ge -- Methods for analyzing histone citrullination in chromatin structure and gene regulation / Pingxin Li, Jing Hu, and Yanming Wang -- Analysis of mRNA abundance and stability by ribonuclease protection assay / Cristina Romero-López [and others] -- Array-based nuclear run-on analysis / Jinshui Fan [and others] -- In vivo run-on assays to monitor nascent precursor RNA transcripts / Piergiorgio Percipalle and Emilie Louvet -- Genome wide full-length transcript analysis using 5' and 3' paired-end-tag next generation sequencing (RNA-PET) / Xiaoan Ruan and Yijun Ruan -- Analysis of co-transcriptional RNA processing by RNA- ChIP assay / Danielle Bittencourt and Didier Auboeuf -- Quantitative analysis of transcription elongation by RNA polymerase I in vitro / David Alan Schneider -- Detection and characterization of transcription termination / Ghada Ghazal, Jules Gagnon, and Sherif Abou Elela -- Promoter-associated noncoding RNA from the CCND1 promoter / Xiaoyuan Song [and others].
  • 2005/2006
    Christopher Bryan Kaelin.
    Status: Not Checked OutLane Catalog Record
  • 2008
    Patrick J. Collins.
    Status: Not Checked OutLane Catalog Record
  • 2006/2007
    Laura Rose Schaevitz.
    Status: Not Checked OutLane Catalog Record
  • 2006
    Kerri E. Rieger.
    Status: Not Checked OutLane Catalog Record
  • 2013
    Joseph William Foley.
    The human genome's nucleotide sequence contains a small amount of information relative to the complexity of the organism. The diversity of developmental programs and stimulus responses is instead enabled by a vast regulatory network of chemical modifications and protein interactions that determine the activity level of each genome element dynamically. Recent advances in molecular profiling techniques have led to the creation of large data sets that assay each regulatory interaction across the entire genome at once, with high sensitivity and precision. Here I introduce a new computational method, UniPeak, that synthesizes the output from any number of these experiments into a single straightforward analysis with rigorous quantitative measures. I then apply this method to the largest available data sets of genome regulation experiments, and integrate them with parallel experiments on genome activity. I discover and characterize novel regulatory interactions, and model how these interactions regulate the activity of genes.
  • 2016 Springer
    Jiaqian Wu, Editor ; Honor editor, Dong Kim.
    The Analyses of Global Gene Expression and Transcription Factor Regulation -- Global Approaches to Alternative Splicing and its Regulation -- Recent Advances and Open Questions -- Long Non-coding RNAs: Critical Regulators for Cell Lineage Commitment in the Central Nervous System -- Gene expression models of signaling pathways -- From Gene Expression to Disease Phenotypes: Network-Based Approaches to Study Complex Human Diseases -- Introduction to Isoform Sequencing using Pacific Biosciences Technology (Iso-Seq) -- Systematic and Integrative Analysis of Gene Expression to Identify Feature Genes Underlying Human Diseases.
  • 2011 CRCnetBASE
    Ajay K. Banga.
    "Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment. Advancements in science combined with the need for diverse drug delivery modalities have introduced a variety of transdermal and intradermal products for existing drugs at a fraction of the cost of new drug development. Commercialization of transdermal drug delivery requires technology from many disciplines beyond pharmaceutical sciences, such as polymer chemistry, adhesion sciences, mass transport, web film coating, printing, and medical technology. A comprehensive discussion of these technologies and practices, Transdermal and Intradermal Delivery of Therapeutic Agents: Application of Physical Technologies, covers: Commercial development of devices and products based on transdermal physical enhancement technologies, Selecting optimal enhancement technology for a specific drug molecule using case studies that cover physicochemical properties as well as practical commercial considerations related to cost, unmet clinical needs, marketing, or intellectual property protection, Technologies such as microneedles, iontophoresis, electroporation, and sonophoresis with examples for delivery of small molecules, cosmeceuticals, proteins, and vaccines, Practical information on experimental procedures and challenges related to skin irritation and safety issues. Up-to-date and accessible to researchers and industry experts, this book provides a comprehensive discussion of the physical approaches and practical considerations for the laboratory and marketplace"--Provided by publisher.
  • 2015 Springer
    Kok-Yang Tan, editor.
    This book discusses in depth the transdisciplinary integration of different components of care in colorectal surgery. Pertinent background information on the complexities of current management in colorectal surgery is first provided, followed by discussion of the role of design thinking in care integration. Subsequent chapters focus on a range of issues associated with surgical and perioperative care in patients undergoing colorectal surgery, with emphasis on how the multiple facets of care can be integrated through a transdisciplinary approach. Each chapter provides helpful take-home messages in bullet point form and numerous informative figures and tables are also included. The authors are surgeons, physicians, anesthetists, oncologists, nurses, and allied health professionals with extensive experience in the field.
  • 2013 ebrary
    Debra Haire-Joshu and Timothy D. McBride, editors ; foreword by Edward F. Lawlor.
    ""This book makes a great leap in the conceptualization of transdisciplinary approaches, as well as provides concrete examples in practice, teaching, policy, and research."" -From the Foreword by Edward F. Lawlor, dean and the William E. Gordon Distinguished Professor, the Brown School; and founding director, Institute for Public Health at Washington University in St. Louis The complexity of public health and social problems is becoming more challenging. Understanding and designing solutions for these problems requires perspectives from multiple disciplines and fields as well
  • 2011 ClinicalKey
    editors-in-chief, Edward A. Dennis, Ralph A. Bradshaw.
    "Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
  • 2006 Springer
    Klaus Dieter Maria Resch.
  • 2014 Springer
    edited by Pierre C. Wong, Wanda C. Miller-Hance.
    Transesophageal echocardiography (TEE) has played an instrumental role among the many advances in the field of congenital heart disease (CHD) that have resulted in successful and continually improving clinical outcomes, today enabling most affected infants and children to live well into adulthood. Ongoing evolution of the technology (including three-dimensional TEE) promises to maintain this imaging approach at the forefront of clinical practice. Competent performance of TEE in the patient with CHD, however, requires a number of essential technical and cognitive skills, in addition to a solid understanding of the broad spectrum of congenital pathology. Thus, the important need for a comprehensive reference on the subject to assist specialists who care for these patients. Transesophageal Echocardiography for Congenital Heart Disease represents a unique work, the only textbook of its kind that focuses specifically upon the applications of TEE in CHD. In each chapter, the contributorshighly regarded specialists and leaders in the fieldprovide practical and instructive information on the many different aspects of CHD evaluation by TEE. The textbook is extensively supplemented with over 700 figures/illustrations and more than 400 high quality videos (available online). This reference will prove an invaluable resource for those who use TEE in the care of both children and adults with CHD, whether they be cardiologists, surgeons, anesthesiologists, intensivists, sonographers, or trainees wishing to obtain basic knowledge or advance their understanding of the field.
  • 2009 Springer
    Mark Belham.
    Introduction -- The left ventricle -- The left atrium -- The mitral valve -- The aortic valve and aorta -- The right heart -- Artificial valves.
  • 2008 Springer
    v. 2 2008 Springer
    edited by Sonia B. Jakowlew.
    v. 1. Basic and clinical biology -- v. 2. Cancer treatment and therapy.
  • 2013 ebrary
    Michael Maccoby [and others].
    "Health care organizations are challenged to improve care at the bedside for patients, learn from individual patients to improve population health, and reduce per capita costs. To achieve these aims, leaders are needed in all parts of the organization need positive solutions. Transforming Health Care Leadership provides healthcare leaders with the knowledge and tools to master the unprecedented level of change that health care organizations and their leaders now face. It also challenges management myths that served in bureaucracies but mislead in learning organizations"--Provided by publisher.
  • 2010 Springer
    Laura Einbinder, Nancy M. Lorenzi, Joan S. Ash, Cynthia S. Gadd, Jonathan Einbinder, editors.
    Back breaking work: implementing a spine registry in an orthopedic clinic / Brian C. Crolet -- A RHIO struggling to form: will it get off the ground? / Paul Zlotnik, Denny Lee, Mike Minear, and Prashila Dullabh -- A rough ride at the Theodore Roosevelt Cancer Center / Karen Albert, Nitika Gupta, Teresa Mason, Purvi Mehta -- Implementation of an electronic prescription writer in ambulatory care / Minhui Xie and Keven B. Johnson -- Online health care: a classic clash of technology, people and processes / John Butler, Dan Dalan, Brian McCourt, John Norris, and Randall Stewart -- A dungeon of dangerous practices / Andrew Amata, Allen Flynn, Michelle Morgan, Teresa Smith, and Mary Tengdin -- Different sides of the story / Allison B. McCoy -- Barcode medication administration implementation in the FIAT Health System / Linda Chan, William Greeley, Don Klingen, Brian Machado, Michael Padula, John Sum, and Angela Vacca -- H.I.T. or Miss / James McCormack, Bimal R. Desai, Jennifer Garvin, Randal Hamric, Kirk Lalwani, Andi Lushag, Alexey Panchenko, Deborah Quitmeyer, and JoAnna M. Vanderhoef -- The implementation of secure messaging / Zhou Yan -- Who moved my clinic? Donnelly University Pediatric Rehabilitation : the wheelchair clinic / Fredrick Hilliard -- OncoOrders: The early years / Chris Raggio and Judith W. Dexheimer -- Implementing a computerized triage system in the emergency department / Scott R. Levin, Daniel J. France, and Dominik Aronsky -- Medication barcode scanning: Code "Moo": dead COW / Laurie L. Novak and Kathy S. Moss -- Project NEED: new efficiency in an emergency department / Barry Little, Denise Johnson, Jennifer Tingle, Mary Stanfill, and Michael Roy. -- Digital radiology divide at McKinly / Neal Goldstein, David Ross, Ken Christensen, Jayashree Kalpathy-Cramer, Aseem Kumar, and Marilyn Schroeder.
  • 2015 ScienceDirect
    Mary Nord Cook.
    Introduction and background -- Parenting approaches for challenging kids; Teen and mastery of psychosocial skills; Teen: overview of format and operations -- Outcome data for PACK and MaPS teen intensive outpatient program -- PACK-Teen treatement protocol -- MaPS-Teen treatment protocol -- Conclusion.
  • 2016 Springer
    William T. Choctaw.
    Change is Inevitable -- The Power of Common Ground -- Relentless Pursuit of Zero Harm -- The Patient Experience -- Physician Champions -- Hospital Champions -- Lean Six Sigma.
  • 2015 Springer
    Nicole P. Juffermans, Timothy S. Walsh, editors.
    In the last decade, there have been several clinical trials that have studied red blood cell transfusion triggers in various Intensive Care Unit patient populations. Moreover, critically ill patients often suffer from coagulopathy. Recent studies have addressed the effectiveness of fresh frozen plasma and platelets to prevent or treat bleeding. This book offers a comprehensive summary of transfusion triggers for red blood cells in specific ICU patient populations and specific conditions with the aim to personalize transfusion strategy. In addition, it discusses evidence for triggers for plasma and platelets and outlines the most common adverse effects of blood transfusion in the ICU, underlining the need for a careful assessment of its risks and benefits. Transfusion in the Intensive Care Unit is a practical handbook that can be used in everyday practice to guide transfusion and thus will serve as a valuable resource for physicians, fellows and residents working in Intensive Care, Anesthesiology, and Cardiac Surgery.
  • 2012 Springer
    [by] Aleksandar Mijovic.
  • 2013 ClinicalKey
    edited by Beth Shaz, Christopher Hillyer, Mikhail Roshal, Charles S. Abrams.
    The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals). Updated content covers new coagulation tests, cellular therapies, and quality control issuesEasy to use, with focused, well-defined chapters in a standardized format throughoutOffers quick "cross-reference" lists at the end of each chapter Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities.
  • 2009 ScienceDirect
    edited by Christopher D. Hillyer, Beth H. Shaz, James C. Zimring, Thomas C. Abshire.
  • 2008
    edited by Serap Aksoy.
    Perspectives on the state of insect transgenics / David A. O'Brochta and Alfred M. Handler -- Alphavirus transducing systems / Brian D. Foy and Ken E. Olson -- Paratransgenesis applied for control of tsetse transmitted sleeping sickness / Serap Aksoy, Brian Weiss, and Geoffrey Attardo -- Bacteria of the genus Asaia: a potential paratransgenic weapon against malaria / Guido Favia ... [et al.] -- Proposed uses of transposons in insect and medical biotechnology / Peter W. Atkinson -- The yin and yang of linkage disequilibrium: mapping of genes and nucleotides -- Conferring insecticide resistance in insect disease vectors / William C. Black IV ... [et al.] -- Impact of technological improvements on traditional control strategies / Mark Q. Benedict and Alan S. Robinson -- Insect population suppression using engineered insects / Luke Alphey ... [et al.] -- Wolbachia-based technologies for insect pest population control / Kostas Bourtzis -- Using predictive models to optimize wolbachia-based strategies for vector-borne disease control / Jason L. Rasgon -- Modifying insect population age structure to control vector-borne disease / Peter E. Cook, Conor J. McMeniman, and Scott L. O'Neill -- Technological advances to enhance agricultural pest management / Thomas A. Miller, Carol R. Lauzon, and David J. Lampe -- Applications of mosquito ecology for successful insect transgenesis-based disease prevention programs / Thomas W. Scott ... [et al.].
  • 2006 Springer
    edited by Gene S. Fisch, Jonathan Flint.
    Transgenic and knockout models of psychiatric disorders: introduction, history, and assessment / Gene S. Fisch -- Transgenic mouse models and human psychiatric disease / Jonathan Flint -- Transgenic and knockout mouse models: the problem of language / Linda J. Hayes and Diana Delgado -- If only they could talk: genetic mouse models for psychiatric disorders / Trevor Humby and Lawrence Wilkinson -- Spinocerebellar ataxia type 1: lessons from modeling a movement disease in mice / Harry T. Orr -- Mouse models of hereditary mental retardation / Hans Welzl ... [et al.] -- How can studies of animals help to uncover the roles of genes implicated in human speech and language disorders? / Simon E. Fisher -- Animal models of autism: proposed behavioral paradigms and biological studies / Thomas Bourgeron, Stéphane Jamain, and Sylvie Granon -- Genetic mouse models of psychiatric disorders: advantages, limitations, and challenges / Joseph A. Gogos and Maria Karayiorgou -- Animal models of psychosis / Stephen I. Deutsch ... [et al.] -- Animal models of anxiety: the ethological perspective / Robert Gerlai, Robert Blanchard, and Caroline Blanchard -- Modeling human anxiety and depression in mutant mice / Andrew Holmes and John F. Cryan -- Mutant mouse models of bipolar disorder: are there any? / Anneloes Dirks, Lucianne Groenink, and Berend Olivier.
  • 2010 Springer Protocols
    edited by Allan V. Kalueff and Carisa L. Bergner.
    Mutant and transgenic zebrafish in modeling neurobehavioral disorders / C.L. Bergner [and others] -- Knockout and mutant rats / M. Müller, J. Olivier and J. Homberg -- Rat mutants with lateralized rotational behavior for studying disturbances in cerebral asymmetries and their involvement in brain disorders / W. Löscher -- GABAA receptor [alpha]1 subunit (Gabra1) knockout mice: Review and new results / G.-L. Ye [and others] -- Basal ganglia disorders in genetic models and experimentally induced lesions / R. Lalonde and C. Strazielle -- Estrogen-deficient mouse models in the study of brain injury and disease / R.A. Hill and W.C. Boon -- The utility of genetically modified animals in modeling OCD-spectrum disorders / A.N. Smolinsky [and others] -- Investigating Rett syndrome through genetic mouse models: Presymptomatic, clearly symptomatic phases, and innovative therapeutic approaches / B. Filippis, L. Ricceri and G. Laviola -- Genetic animal models of anxiety / R.J. Egan [and others] -- Genetic animal models of depression / P.R. Canavello [and others] -- Environmental enrichment and gene-environment interactions in mouse models of brain disorders / A.J. Hannan -- Mutant and transgenic tools in modeling schizophrenia / L. Desbonnet [and others].
  • 2006
    first draft prepared by Ulrich Wahnschaffe, Janet Kielhorn, Annette Bitsch and Inge Mangelsdorf.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer Protocols
    edited by Baohong Zhang.
    Transgenic cotton : from biotransformation methods to agricultural application / Baohong Zhang -- Genetically modified cotton in India and detection strategies / Gurinder Jit Randhawa and Rashmi Chhabra -- Agrobacterium-mediated transformation of cotton / Baohong Zhang -- Biolistic transformation of cotton zygotic embryo meristem / Kanniah Rajasekaran -- Biolistic transformation of cotton embryogenic cell suspension cultures / Kanniah Rajasekaran -- Cotton transformation via pollen tube pathway / Min Wang, Baohong Zhang, and Qinglian Wang -- Silicon carbide whisker-mediated transformation of cotton (Gossypium hirsutum L.) / Muhammad Arshad, Yusuf Zafar, and Shaheen Asad -- Investigating transgene integration and organization in cotton (Gossypium hirsutum L.) genome / Jun Zhang and Yan Hong -- Estimating the copy number of transgenes in transformed cotton by real-time quantitative PCR / Chengxin Yi and Yan Hong -- Development of enzyme-linked immunosorbent assay for the detection of Bt protein in transgenic cotton / Suchitra Kamle, Abhishek Ojha, and Arvind Kumar -- DNA-based diagnostics for genetically modified cotton : decaplex PCR assay to Differentiate MON531 and MON15985 Bt cotton events / Gurinder Jit Randhawa, Monika Singh, and Rashmi Chhabra -- Simple and rapid method for determining transgenic cotton plants / Baohong Zhang [and others] -- Efficient grafting technique for recovery of transgenic cotton plants / Min Wang, Qinglian Wang, and Baohong Zhang -- Inheritance of transgenes in transgenic Bt lines resistance to Helicoerpa armigera in upland cotton / Baolong Zhang, Wangzhen Guo, and Tianzhen Zhang -- Agrobacterium rhizogenes-induced cotton hairy root culture as an alternative tool for cotton functional genomics / Hee Jin Kim -- Overexpression of miR 156 in cotton via Agrobacterium-mediated transformation / Baohong Zhang [and others] -- Development of transgenic CryIA(c) + GNA cotton plants via pollen tube pathway method confers resistance to Helicoverpa armigera and Aphis gossypii Glover / Zhi Liu, Zhen Zhu, and Tianzhen Zhang -- Agrobacterium-mediated transformation of cotton (Gossypium hirsutum) shoot apex with a fungal phytase gene improves phosphorus acquisition / Zhiying Ma, Jianfeng Liu, and Xingfen Wang -- Genetic transformation of cotton with a harpin-encoding gene hpaXoo confers an enhanced defense response against Verticillium dahliae kleb / Weiguo Miao and Jingsheng Wang -- Development of insect-resistant transgenic cotton with chimeric TVip3A* accumulating in chloroplasts / Jiahe Wu and Yingchuan Tian -- Determining gene flow in transgenic cotton / Xiaoping Pan.
  • 2007
    edited by Rosa León, Aurora Gaván, Emilio Fernández.
    In the grip of algal genomics / Arthur R. Grossman -- Insertional mutagenesis as a tool to study genes/functions in chlamydomonas / Aurora Gaván, David González-Ballester, and Emilio Fernández -- Optimization of recombinant protein expression in the chloroplasts of green algae / Samuel P. Fletcher, Machiko Muto, and Stephen P. Mayfield -- Nuclear transformation of eukaryotic microalgae : historical overview, achievements, and problems / Rosa León and Emilio Fernández -- Transformation of cyanobacteria / Agustín Vioque -- Molecular biology and the biotechnological potential of diatoms / Peter Kroth -- Tools and techniques for chloroplast transformation of chlamydomonas / Saul Purton -- Phycoremediation of heavy metals using transgenic microalgae / Sathish Rajamani ... [et al.] -- Hydrogen fuel production by transgenic microalgae / Anastasios Melis, Michael Seibert, and Maria L. Ghirardi -- Microalgal vaccines / Surasak Siripornadulsil, Konrad Dabrowski, and Richard Sayre.
  • 2011 Springer Protocols
    edited by Marten H. Hofker, Jan van Deursen.
    Introduction: strategies for developing genetically modified mice / Marten H. Hofker -- Genetic modification of the mouse: general technology - pronuclear and blastocyst injection / Jan Willem Voncken -- Generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos / Jérôme Artus and Anna-Katerina Hadjantonakis -- Cryopreservation of mouse spermatozoa and in vitro fertilization / Naomi Nakagata -- Autopsy and histological analysis of the transgenic mouse / Marion J.J. Gijbels and Menno P.J. de Winther -- Transgene design / Bart van de Sluis and Jan Willem Voncken -- Inducible transgenic mouse models / Thomas L. Saunders -- Lentiviral transgenesis / Terunaga Nakagawa and Casper C. Hoogenraad -- Transgenesis in mouse embryonic stem cells / Janine van Ree, Wei Zhou, Ming Li, and Jan M. van Deursen -- Engineering BAC reporter gene constructs for mouse transgenesis / Yu Fu and Peter Maye -- Targeting vector construction through recombineering / Liviu A. Malureanu -- Generating conditional knockout mice / Roland H. Friedel, Wolfgang Wurst, Benedikt Wefers, and Ralf Kühm -- Hypomorphic mice / Darren J. Baker -- MICER targeting vectors for manipulating the mouse genome / Chunbong Liu, Paul F. Szurek, and Y. Eugene Yu -- Knock-in approaches / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans -- Generation of a series of knock-in alleles using RMCE in ES cells / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans -- Selection of targeting mutants from a library of randomly mutagenized ES cells / Kyoji Horie, George Gaitanaris, and Alexander Gragerov -- Generation of genetically modified rodents using random ENU mutagenesis / Ruben van Boxtel and Edwin Cuppen -- Bone marrow transplantations of study gene function in hematopoietic cells / Menno P.J. de Winther and Peter Heeringa -- Adenovirus-mediated gene transfer / Ko Willems van Dijk, Kyriakos E. Kyreos, Frits J. Fallaux, and Jurre Hageman.
  • 2012 Springer Protocols
    edited by Jim M. Dunwell, Andy C. Wetten.
    Employment of cytokinin vectors for marker-free and backbone-free transformation -- Organophosphorus hydrolase: A multifaceted plant genetic marker which is selectable, scorable, and quantifiable in whole seed -- Use of northern blotting for specific detection of small RNA molecules in transgenic plants -- Genetic transformation of the model green alga Chlamydomonas reinhardtii -- A high-efficiency agrobacterium-mediated transformation system of rice (Oryza sativa L.) -- Selection of transgenic rice plants using a herbicide tolerant form of the acetolactate synthase gene -- Visual selection in rice: A strategy for the efficient identification of transgenic calli accumulating transgene products -- Characterization of rice genes using a heterologous full-length cCDNA expression system -- Bioactive bead-mediated transformation of plants with large DNA fragments -- Agrobacterium-mediated transformation of sorghum bicolor using immature embryos -- Split-transgene expression in wheat -- Agrobacterium-mediated transformation of brachypodium distachyon -- Transformation of barley (Hordeum vulgare L.) by agrobacterium tumefaciens infection of in vitro cultured ovules -- Biolistic-mediated production of transgenic oil palm -- Transformation of oil palm using agrobacterium tumefaciens -- Highly efficient transformation protocol for plum (Prunus domestica L.) -- Co-transformation of grapevine somatic embryos to produce transgenic plants free of marker genes -- Initiation and transformation of grapevine embryogenic cultures -- Development of highly efficient genetic transformation protocols for table grape sugraone and crimson seedless -- Cotton pistil drip transformation method -- Enhanced agrobacterium-mediated transformation of embryogenic calli of upland cotton -- Targeted biolistics for improved transformation of impatiens balsamina -- A protocol for transformation of torenia -- Efficient modification of floral traits by heavy-ion beam irradiation on transgenic torenia -- Expression of artificial micrornas in physcomitrella patens -- High frequency of single-copy t-DNA transformants produced after floral dip in CRE-expressing arabidopsis plants -- A developmentally regulated cre-lox system to generate marker-free transgenic Brassica napus plants -- Exploiting multisite gateway and pENFRUIT plasmid collection for fruit genetic engineering -- A one-time inducible transposon to create knockout mutants in rice -- Marker-free gene targeting by recombinase-mediated cassette exchange -- Targeting DNA to a previously integrated transgenic locus using zinc finger nucleases -- Double-strand break-induced targeted mutagenesis in plants -- Combinatorial genetic transformation of cereals and the creation of metabolic libraries for the carotenoid pathway -- Production of a his-tagged canecystatin in transgenic sugarcane -- Plastid transformation as an expression tool for plant-derived biopharmaceuticals -- Use of a callus-specific selection system to develop transgenic rice seed accumulating a high level of recombinant protein -- How to grow transgenic arabidopsis in the field.
  • 2009 Springer Protocols
    edited by Huw D. Jones and Peter R. Shewry.
    Transgenic wheat, barley and oats : production and characterization / Paul A. Lazzeri and Huw D. Jones -- Selection of transformed plants / Huw D. Jones and Caroline A. Sparks -- Reporter genes / Alison Huttly -- Biolistics transformation of wheat / Caroline A. Sparks and Huw D. Jones -- Agrobacterium-mediated transformation of bread and durum wheat using freshly isolated immature embryos / Huixia Wu, Angela Doherty and Huw D. Jones -- Floral transformation of wheat / Sujata Agarwal ... [et al.] -- Highly efficient agrobacterium-mediated transformation of wheat via in planta inoculation / Thierry Risacher ... [et al.] -- Barley transformation using biolistic techniques / Wendy A. Harwood and Mark A. Smedley -- Barley transformation using agrobacterium-mediated techniques / Wendy A. Harwood ... [et al.] -- Transformation of oats and its application to improving osmotic stress tolerance / Shahina B. Maqbool ... [et al.] -- Promoter sequences for defining transgene expression / Huw D. Jones and Caroline A. Sparks -- Down-regulation of gene expression by RNA-induced gene silencing / Silvia Travella and Beat Keller -- Gene insertion patterns and sites / Philippe Vain and Vera Thole -- Fluorescent in situ hybridization to detect transgene integration into plant genomes / Trude Schwarzacher -- Establishing substantial equivalence : transcriptomics / María Marcela Baudo ... [et al.] -- Establishing substantial equivalence : proteomics / Alison Lovegrove, Louise Salt, and Peter R. Shewry -- Establishing substantial equivalence : metabolomics / Michael H. Beale, Jane L. Ward, and John M. Baker -- Design and management of field trials of transgenic cereals / Zoltán Bedő, Mariann Rakszegi, and László Láng -- GM risk assessment / Penny A.C. Sparrow -- Transgenic wheat, barley and oats : future prospects / Jim M. Dunwell.
  • 2005 Karger
    volume editors, Kapil Mehta, Richard Eckert.
    Mammalian transglutaminases : a family portrait / Mehta, K. -- Structure-function relationships of transglutaminases, a contemporary view / Nemes, Z., Csosz, E., Fesus, L. -- Transglutaminases and their substrates / Facchiano, F., Facchiano, A. -- Type 2 transglutaminase and cell death / Piacentini, M. ... [et al.] -- Transglutaminase and cell-survival signaling / Singh, U.S., Pan, J. -- Transglutaminases in wound healing and inflammation / Verderio, E.A.M., Johnson, T.S., Griffin, M. -- Transglutaminases in epidermis / Eckert, R.L. ... [et al.] -- Tissue transglutaminase (TG2) in cancer biology / Mangala, L.S., Mehta, K. -- Transglutaminases in neurodegenerative disorders / Bailey, C.D.C., Tucholski, J., Johnson, G.V.W. -- Tissue transglutaminase and celiac disease / Esposito, C. ... [et al.] -- Transglutaminases as biotechnological tools / Mariniello, L., Porta, R. -- Extracellular transglutaminase: factor XIII / Ichinose, A. -- Transglutaminases of lower organisms / Rao, R.U., Chandrashekar, R., Mehta, K. -- Transglutaminases of higher, lower plants and fungi / Del Duca, S., Serafini-Fracassini, D.
  • 2013 Wiley
    edited by Max More and Natasha Vita-More.
    The first authoritative and comprehensive survey of the origins and current state of transhumanist thinking The rapid pace of emerging technologies is playing an increasingly important role in overcoming fundamental human limitations. Featuring core writings by seminal thinkers in the speculative possibilities of the posthuman condition, essays address key philosophical arguments for and against human enhancement, explore the inevitability of life extension, and consider possible solutions to the growing issues of social and ethical implications and concerns.
  • 2011 Springer
    Md. Shahidul Islam, editor.
    Also available: Print – 2011
  • 2007 Springer
    contributors: J. Abramowitz ... [et al.] ; editors, Veit Flockerzi and Bernd Nilius.
  • 2015 Springer
    Hadley M. Wood, Dan Wood, editors.
    1. The transition process: initial assessment and development of a treatment plan -- 2. Approach to the myelodysplasia patient -- 3. Approach to the exstrophy patient -- 4. Approach to the adult hypospadias patient -- 5. Sexual function and pregnancy in the female myelodyspasia patient -- 6. Revision genitoplasty, sexual function, fertility, and pelvic organ prolapse in exstrophy and the management of pregnancy -- 7. Issues in the long-term management of adolescents and adults with DSD: management of gonads, genital reconstruction, and late presentation of the undiagnosed DSD -- 8. The adult hypospadias patient: technical challenges in adulthood -- 9. Urinary tract infections in the reconstructed bladder: evaluation and treatment options -- 10. Troubleshooting continent catheterizable channels -- 11. Augmentation cytosplasty: risks for malignancy and suggestions for follow-up evaluations -- 12. BPH and pelvic organ prolapse in patients with neurogenic bladder -- 13. Posterior urethral valves in adolescents: clinical problems, management, and follow-up -- 14. Renal transplantation in patients with lower urinary tract dysfunction -- 15. Management of calculi in patients with congenital neuropathic bladder -- 16. Vesicoureteral reflux and the adult -- 17. Adult survivors of pediatric genitourinary tumors -- Index.
  • 2010
    Robert D. Rondinelli, Marjorie Eskay-Auerbach.
    Status: Not Checked OutLane Catalog Record
    Conceptual foundations and philosophy -- Practical application of the guides -- Pain-related impairment -- The cardiovascular system -- The pulmonary system -- The digestive system -- The urinary and reproductive systems -- The skin -- The hematopoietic system -- The endocrine system -- Ear, nose, throat, and related structures -- The visual system -- The central and peripheral nervous system -- Mental and behavioral disorders -- The upper extremities -- The lower extremities -- The spine and pelvis.
  • 2015
    Investigators: Devan Kansagara, MD, MCR, Joseph C Chiovaro, MD, David Kagen, MD, Stephen Jencks, MD, MPH, Kerry Rhyne, MD, Maya O'Neil, PhD, Karli Kondo, PhD, Rose Relevo, MLIS, MS, Makalapua Motu'apuaka, BS, Michele Freeman, MPH, and Honora Englander, MD.
  • 2003 Stanf Univ SOM
    [Stanford University School of Medicine].
  • 2013 Springer
    Anne-Marie Duchêne, editor.
    Insights into Structural Basis of Mammalian Mitochondrial Translation / Manjuli R. Sharma, Prem S. Kaushal -- Mechanism and Regulation of Protein Synthesis in Mammalian Mitochondria / Emine C. Koc, Hasan Koc -- Translation in Mammalian Mitochondria: Order and Disorder Linked to tRNAs and Aminoacyl-tRNA Synthetases / Catherine Florentz, Joern Pütz -- Mitochondrial Targeting of RNA and Mitochondrial Translation / Ivan Tarassov, Ivan Chicherin, Yann Tonin -- Mechanisms and Control of Protein Synthesis in Yeast Mitochondria / Steffi Gruschke, Martin Ott -- Kinetoplast-Mitochondrial Translation System in Trypanosomatids / Dmitri A. Maslov, Rajendra K. Agrawal -- Translation in Mitochondria and Apicoplasts of Apicomplexan Parasites / Ankit Gupta, Afreen Haider, Suniti Vaishya -- Mitochondrial Translation in Green Algae and Higher Plants / Thalia Salinas, Claire Remacle -- Translation in Chloroplasts of Flowering Plants / Masahiro Sugiura -- The Chloroplasts as Platform for Recombinant Proteins Production / Nunzia Scotti, Michele Bellucci.
  • 2007 ScienceDirect
    edited by Jon Lorsch.
    Purification of FLAG-tagged eukaryotic initation factor 2B complexes, subcomplexes, and fragments from Saccharomyces cerevisiae / Sarah S. Mohammad-Qureshi ... [et al.] -- In vivo deletion analysis of the architecture of a multiprotein complex of translation initiation factors / Klaus H. Nielsen and Leos̆ Valás̆ek -- An approach to studying the localization and dynamics of eukaryotic translation factors in live yeast cells / Susan G. Campbell and Mark P. Ashe -- In vitro and tissue culture methods for analysis of translation initiation on the endoplasmic reticulum / Samuel B. Stephens and Christopher V. Nicchitta -- Mammalian stress granules and processing bodies / Nancy Kedersha and Paul Anderson -- Methods to analyze micro-RNA-mediated control of mRNA translation / Jennifer L. Clancy ... [et al.] -- Methods for studying signal-dependent regulation of translation factor activity / Xuemin Wang and Christopher G. Proud -- Analysis of mRNA translation in cultured hippocampal neurons / Yi-Shuian Huang and Joel D. Richter -- Detecting ribosomal association with the 5' leader of mRNAs by ribosome density mapping (RDM) / Naama Eldad and Yoav Arava -- Genome-wide analysis of mRNA polysomal profiles with spotted DNA microarrays / Danial Melamed and Yoad Arava -- Synthesis of anti-reverse cap analogs (ARCAs) and their applications in mRNA translation and stability / Ewa Grudzien-Nogalska ... [et al.] -- Methods for identifying compounds that specifically target translation / Letizia Brandi ... [et al.] -- Identifying small molecule inhibitors of eukaryotic translation initiation / Regina Cencic, Francis Robert, and Jerry Pelletier -- Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product pateamine A / Woon-Kai Low ... [et al.].
    Also available: Print – 2007
  • 2007 ScienceDirect
    edited by Jon Lorsch.
    Use of reticulocyte lysates for mechanistic studies of eukaryotic translation initiation / William C. Merrick and Diane Barth-Baus -- Studying translational control in Drosophila cell-free systems / Fátima Gebauer and Matthias W. Hentze -- Use of in vitro translation extract depleted in specific initiation factors for the investigation of translational regulation / Daniel R. Gallie -- A highly efficient and robust in vitro translation system for expression of picornavirus and hepatitis C virus in RNA genomes / Yuri V. Svitkin and Nahum Sonenberg -- A practical approach to isolate 48S complexes : affinity purification and analyses / Nicolas Locker and Peter J. Lukavsky -- Yeast phenotypic assays on translational control / Bumjun Lee ... [et al.] -- Localization and characterization of protein-protein interaction sites / Chingakham Ranjit Singh and Katsura Asano -- In vivo stabilization of preinitiation complexes by formaldehyde cross-linking / Leos Valás̆ek ... [et al.] -- Molecular genetic structure-function analysis of translation initiation factor elF5B / Byung-Sik Shin and Thomas E. Dever -- The use of fungal in vitro systems for studying translational regulation / Cheng Wu ... [et al.] -- Investigating translation initiation using drosophila molecular genetics / Gritta Tettweiler and Paul Lasko -- Analysis of RNA:protein interactions in vivo : identification of RNA-binding partners of nuclear factor 90 / Andrew M. Parrott, Melissa R. Walsh, and Michael B. Mathews -- Approaches for analyzing the differential activities and functions of elF4E family members / Robert E. Rhoads, Tzvetanka D. Dinkova, and Rosemary Jagus -- Tethered function assays : an adaptable approach to study RNA regulatory proteins / Jeff Coller and Marv Wickens -- Analysis of ribosomal shunting during translation initiation in eukaryotic mRNAs / Vincent P. Mauro, Stephen A. Chappell and John Dresios.
    Also available: Print – 2007
  • 2007 ScienceDirect
    edited by Jon Lorsch.
    Transient kinetics, flourescence, and FRET in studies of initiation and translation in bacteria / Pohl Milon ... [et al.] -- Binding of mRNA to the bacterial translation initiation complex / Sean M. Studer and Simpson Joseph -- Real-time dynamics of ribosome-ligand interaction by time-resolved chemical probing methods / Attilio Fabbretti ... [et al] -- Overexpression and purification of mammalian mitochondrial translational initiation factor 2 and initiation factor 3 / Domenick G. Grasso ... [et al.] -- In vitro studies of archaeal translational initiation / Dario Benelli and Paola Londei -- Reconstitution of yeast translation initiation / Michael G. Acker ... [et al.] -- Assembly and analysis of eukaryotic translation initiation complexes / Andrey V. Pisarev -- Reconstitution of mammalian 48S ribosomal translation initiation complex / Romit Majumdar, Jayanta Chaudhuri, and Umadas Maitra -- Biophysical approach to studies of Cap-elF4E interaction by synthetic cap analogs / Anna Niedzwiecka ... [et al.] -- Biophysical studies of the translation initiation pathway with immobilized mRNA analogs / John E. G. McCarthy, Steven Marsden, and Tobias von der Haar -- Protection-based assays to measure aminoacyl-tRNA binding to translation initiation factors / Yves Mechulam ... [et al.] -- NMR methods for studying protein-protein interactions involved in translation initiation / Assen Marintchev, Dominique Frueh, and Gerhard Wagner -- Structural methods for studying IRES function / Jeffrey S. Kieft ... [et al.].
    Also available: Print – 2007
  • 2013 Springer
    Jozef Bartunek, Marc Vanderheyden, editors.
    Pathophysiology of Heart Failure: Back to Basics -- Heart Failure with Normal Left Ventricular Ejection Fraction -- Basic Principles and Clinical Diagnostics -- 17 Cardiorenal Syndrome Revisited -- Doppler Echocardiography in the Clinical Evaluation of Heart Failure: What Clinicians Need to know and Echocardiographers Should Report -- Back to Earth: 'Common sense' in the Management of Heart Failure -- Atrial Fibrillation and Heart Failure: Rate versus Rhythm Control -- Repetitive ICD Shocks and Incessant VTs in Heart Failure: What to Do? -- Dyssynchronous Heart Failure: From Bench to Bedside -- 18 Telemonitoring and Sensor Technologies in Chronic Heart Failure -- Functional Mitral Regurgitation: the Surgeons's Perspective -- Percutaneous Approaches to Treat Functional Mitral Regurgitation: Current State of Affairs and Future Perspectives -- Tailored Approach to Functional Mitral Regurgitation -- Revascularization and Left Ventricular Reconstruction in a Patient with Ischemic Heart Failure: to STICH or not to STICH? -- Cardiac arrest en Refractory Cardiogenic Shock -- Left Ventricular Assist Devices -- From Bridge to Transplant to Destination Therapy -- Novel Device-based Strategies in Treatment of Chronic Heart Failure -- Total Artificial Heart -- Stem Cell Therapy for Ischemic Heart Disease -- Immunosuppressive Management of the Heart Transplant Recipient.
  • v. 1-, 2012- Springer
    Wang, Xiangdong.
  • 2015 ScienceDirect
    Monty Montano.
  • edited by Michael B. Mathews, Nahum Sonenberg, John W.B. Hershey.
  • 2015 Springer
    Philip R.O. Payne, Peter J. Embi, editors.
    Pt. I. The rationale for translational informatics -- An introduction to translational informatics and the future of knowledge-driven healthcare -- A prototype of translational informatics in action -- pt. II. Foundations of translational informatics -- Personalized medicine -- Leveraging electronic health records for phenotyping -- Mining the bibliome -- pt. III. Applications of translational informatics -- Driving clinical and translational research using biomedical informatics -- Using big data -- In silico hypothesis discovery -- Patient engagement and consumerism -- pt. IV. The future of translational informatics and knowledge-driven healthcare -- Future directions for translational informatics.
  • 2009 CRCnetBASE
    edited by Dennis Cosmatos, Shein-Chung Chow.
    Chapter 1. Translational Medicine / Dennis Cosmatos, Shein-Chung Chow -- Chapter 2. Strategic Concepts in Translational Medicine / Dennis Cosmatos, Giora Feuerstein, Shein-Chung Chow -- Chapter 3. Design and Analysis Approaches for Discovery Translational Medicine / Dennis Cosmatos, Shein-Chung Chow (Eds.), Stephen B. Forlow, Jennifer A. Isler, Zhaosheng Lin, Michael E. Burczynski, Jessie Q. Xia, S. Stanley Young -- Chapter 4. Biomarker Development / Mark Chang -- Chapter 5. Targeted Clinical Trials / Jen-pei Liu -- Chapter 6. Statistical Methods in Translational Medicine / Shein-Chung Chow, Siu-Keung Tse, Dennis Cosmatos -- Chapter 7. Nonparametric Methods in Translational Research / Kongming Wang, Shein-Chung Chow -- Chapter 8. Model Selection/Validation / Jen-pei Liu -- Chapter 9. Translation in Clinical Information between Populations-Bridging Studies / Chin-Fu Hsiao, Mey Wang, Herng-Der Chern, Jen-pei Liu -- Chapter 10. Translation in Clinical Technology-Traditional Chinese Medicine / Chin-Fu Hsiao, Hsiao-Hui Tsou, Shein-Chung Chow.
  • 2013 Karger
    volume editors, Barbara Alving, Kerong Dai, Samuel H.H. Chan.
  • 2013 CRCnetBASE
    edited by James Mittra, Christopher-Paul Milne.
    Chapter 1. Introduction to Translational Medicine -- Chapter 2. New Light Through an Old Window? The "Translational Turn" in Biomedical Research -- Chapter 3. Translational Medicine -- Drivers and Barriers of TM -- Chapter 5. Developing an Evaluation Model for Translational Medicine Research Programs -- Chapter 6. Emerging Concepts in Biomarker Discovery -- Chapter 7. Imaging Biomarkers for Innovative Drug Development -- Chapter 8. Translational Bioinformatics -- Chapter 9. Exploiting Translational Medicine Through Public- Private Partnerships -- Chapter 10. The Role of the Product Development Partnership as a Translational Mechanism for Delivering Health Solutions in Low- Resource Settings.
  • 2012
    Michael Richard Stadler.
    The conversion of genetic information from the language of nucleic acids into that of proteins is fundamental to nearly every biological process. The regulation of this process of gene expression--when, where, and how much product is produced from each gene--is a crucial determinant of cell state and identity. Gene expression is tightly regulated at every metabolic step, including transcription of DNA into mRNA, splicing of introns, export from the nucleus, polypeptide synthesis, and post-translational modification and stability. Regulation of protein synthesis acts directly or indirectly through the ribosome, as it is the interaction of ribosomes with mRNAs and dozens of protein and RNA translation factors that determine the efficiency and fidelity of translation. Emerging technologies allow the analysis of translation in contexts that were previously inaccessible. In my thesis work, I employed a technique known as ribosome profiling to examine snapshots of the positions of millions of ribosomes on cellular mRNAs in vivo. In the first part of my thesis, I used ribosome profiling data from Caenorhabditis elegans and cultured human tumor cells to investigate the sequence determinants of the rate of ribosome elongation. The genetic code is redundant, meaning that a single amino acid can usually encoded by more than one trinucleotide sequence, or codon. The choice from among these "synonymous" codons has long been suspected to influence local ribosomal elongation rates, with possible consequences on the folding of nascent polypeptides. By examining "snapshots" of the in vivo positions of ribosomes on thousands of mRNAs, we were able to determine that mRNA positions featuring "wobble" codons in the ribosomal decoding center were associated with greater ribosome occupancy, and thus most likely with slower translation elongation. These wobble codons pair with cognate tRNA anticodons using alternative base-pairing strategies that are less energetically stable than canonical Watson-Crick interactions. The observed wobble retention was strong for codons that employ G:U pairing at the wobble position, and weaker for those using I:U pairs. Importantly, this property of translation elongation was observed in both C. elegans samples and human cells, indicating that wobble-related slowing is a conserved feature of metazoan translation. In the second part of my thesis, I used ribosome profiling, together with traditional, low-throughput methods to investigate the molecular consequences of regulation by C. elegans miRNAs. miRNAs are post-transcriptional regulators of gene expression that have been proposed to act by directing mRNA degradation, deadenylation, translation initiation, by interfering with a post-initiation stage of translation or by triggering proteolysis. C. elegans features several well-validated, natural miRNA::mRNA interactions that serve to reduce target protein levels at specific developmental time points as part of the so-called heterochronic pathway. mRNA-seq measurements confirmed earlier observations from other groups that the abundance of target mRNAs decreases only slightly upon the onset of miRNA regulation. Analysis of ribosome footprint abundance showed that miRNA regulation is often associated with decreased ribosome loading in later larval stages, but changes in ribosome loading are negligible at time points where miRNA inhibition becomes active. Additionally, profiles of ribosome footprints did not appreciably change, rendering several models of post-initiation translational regulation unlikely. These data suggest a model in which processes beyond mRNA degradation and translational repression contribute to regulation by this set of miRNAs, including a possible role for post- or peri-translational destruction of peptide products.
  • 2012 Cambridge
    edited by James E. Barrett, Joseph T. Coyle, Michael Williams.
    A comprehensive and authoritative analysis of translational neuroscience, covering all major areas of psychiatry, neurology and neurodevelopmental disorders.
  • 2015 Karger
    volume editors, A. Alonso, M.G. Hennerici, S. Meairs.
    Principles of cerebral ultrasound contrast imaging / Powers, J., Averkiou, M. -- Physical principles of microbubbles for ultrasound imaging and therapy / Stride, E. -- Ultrasound bio-effects and safety considerations / Ter Haar, G. -- Intima-media thickness of carotid arteries / Touboul, P.-J. -- Functional TCD : regulation of cerebral hemodynamics, cerebrovascular autoregulation, vasomotor reactivity, neurovascular coupling / Wolf, M.E. -- Intracranial perfusion imaging with ultrasound / Meairs, S., Kern, R. -- Parenchymal imaging in movement disorders / Fernandes, R.C.L., Berg, D. -- Sonothrombolysis / Meairs, S. -- Non-invasive transcranial brain ablation with high-intensity focused ultrasound / Jenne, J.W. -- Ultrasound-induced blood-brain barrier opening for drug delivery / Alonso, A.
  • 2010 CRCnetBASE
    edited by Lawrence Kruger, Alan R. Light.
    Painful multi-symptom disorders : a systems perspective / C. Richard Chapman -- Neurotrophic factors and nociceptor sensitization / Michael P. Jankowski and H. Richard Koerber -- The role of visceral afferents in disease / Julie A. Christianson and Brian M. Davis -- Cancer pain : from the development of mouse models to human clinical trials / Juan Miguel Jimenez Andrade and Patrick Mantyh -- Therapeutic targeting of peripheral cannabinoid receptors in inflammatory and neuropathic pain states / Igor Spigelman -- Molecular strategies for therapeutic targeting of primary sensory neurons in chronic pain syndromes / Ichiro Nishimura ... [et al.] -- Transgenic mouse models for the tracing of "pain" pathways / Allan I. Basbaum and João M. Bráz -- Cytokines in pain / Veronica I. Shubayev, Kinshi Kato, and Robert R. Myers -- Glial modulation in pain states : translation into humans / Ryan J. Horvath, Edgar Alfonso Romero-Sandoval, and Joyce A. De Leo -- On the role of ATP-gated P2X receptors in acute, inflammatory, and neuropathic pain / Estelle Toulme ... [et al.] -- Myalgia and fatigue : translation from mouse sensory neurons to fibromyalgia and chronic fatigue syndromes / Alan R. Light, Charles J. Vierck, and Kathleen C. Light -- Reflex autonomic responses evoked by group III and IV muscle afferents / Jennifer L. McCord and Marc P. Kaufman -- Central pain as a thalamocortical dysrhythmia : a thalamic efference disconnection? / Kerry D. Walton and Rodolfo R. Llinás -- What can neuroimaging tell us about central pain? / D.S. Veldhuijzen ... [et al.] -- Human brain imaging studies of chronic pain : translational opportunities / A. Vania Apkarian -- Consideration of pharmacokinetic pharmacodynamic relationships in the discovery of new pain drugs / Garth T. Whiteside and Jeffrey D. Kennedy -- Large animal models for pain therapeutic development / Darrell A. Henze and Mark O. Urban -- Drug discovery and development for pain / Sandra R. Chaplan, William A. Eckert III, and Nicholas I. Carruthers.
  • 2015 ScienceDirect
    edited by Anthony Atala, Julie G. Allickson.
    The landscape of cell tissues and organs / Mahendra Rao -- Landscape of cell banking / Heather C. Hatcher, Anthony Atala and Julie G. Allickson -- Cell banking: process development and cell preservation / Salem Akel -- Clinical development of placental mesenchymal stromal cells / Robert J. Hariri and Steven Fischkoff -- Translation of regenerative medicine products into the clinic in the United States: FDA perspective / Mark H. Lee, Patrick Au, John Hyde, Carmen Gacchina Johnson, Mohammad Heidaran, Safa Karandish, Lynne Boxer, Michael Mendicino, Diana Yoon, Lori Tull, Judith Arcidiacono, Brent McCright, David S. Kaplan, Donald Fink, Charles N. Durfor, Richard McFarland and Celia Witten -- Newborn stem cell banking business models / Thomas Moore, Matthew P. Brown, John R. Chapman, Jesse Kramer, Robert P. Pfotenhauer and Heather L. Brown -- Cell therapy landscape: autologous and allogeneic approaches / Nafees N. Malik and Matthew B. Durdy -- Stem cells and cell therapy: autologous cell manufacturing / Ronnda L. Bartel -- Overview: challenges of process development for cellular therapy / Robert Perry -- Tissue engineering: propagation and potency evaluation / Ivan N. Rich -- Biomaterials in preclinical approaches for engineering skeletal tissues / Márcia T. Rodrigues, Pedro P. Carvalho, Manuela E. Gomes and Rui L. Reis -- Biomaterials in regenerative medicine: considerations in early process development / Alexander M. Tatara, Anthony Ratcliffe, Mark E.K. Wong, F. Kurtis Kasper and Antonios G. Mikos -- Biomaterials in regenerative medicine: challenges in technology transfer from science to process development / Prafulla Chandra, James J. Yoo and Sang Jin Lee -- Paracrine regulation from tissue engineered constructs / Or Gadish and Elazer R. Edelman -- Creating commercial value from biomaterials / Glenn D. Prestwich and Brenda K. Mann -- Manufacturing of regenerative medicine products / Tom Spencer and Deepak Jain -- Regulatory aspects / Joyce L. Frey-Vasconcells -- Global design for clinical trials / Yoshito Ikada -- Biomarkers / Ralf Huss -- Translational animal models for regenerative medicine research / John G. Sharp -- Translational imaging for regenerative medicine / Sneha S. Kelkar and Aaron M. Mohs -- Skin and skin appendage regeneration / Krzysztof Kobielak, Eve Kandyba and Yvonne Leung -- Clinical aspects of regenerative medicine: tendon, ligament, and joint / Steven Sampson, Angie Botto-van Bemden and Danielle Aufiero -- Bone regeneration / Suzanne Stewart, Stephanie J. Bryant, Jaimo Ahn and Kurt D. Hankenson -- Regenerative medicine therapies using adipose-derived stem cells / Jolene E. Valentin, Albert D. Donnenberg, Kacey G. Marra and J. Peter Rubin -- Transplantation of myogenic cells in duchenne muscular dystrophy patients: clinical findings / Daniel Skuk and Jacques P. Tremblay -- Regeneration of the vascular system / Etai Sapoznik, Guoguang Niu, Masashi Nomi, Zhan Wang and Shay Soker -- Hematopoiesis in regenerative medicine / Graça Almeida-Porada and Christopher D. Porada -- The application and future of neural stem cells in regenerative medicine / Shreyasi Das, Brian Tobe, Paul A. Jain, Walter Niles, Alicia Winquist, Lina Mastrangelo and Evan Y. Snyder -- Central nervous system / Anup Tuladhar, Nikolaos Mitrousis, Tobias Führmann and Molly S. Shoichet -- In situ tissue engineering bone regeneration in jaw reconstruction / Robert E. Marx -- Regenerative medicine for diseases of the respiratory system / Mei Ling Lim, Philipp Jungebluth and Paolo Macchiarini -- Renal system / Joao Paulo Zambon, Prafulla Chandra, Anthony Atala and James J. Yoo -- Translational regenerative medicine -- hepatic systems / Abritee Dhal, Dipen Vyas, Emma C. Moran, Daniel B. Deegan, Shay Soker and Pedro M. Baptista -- Advances in neo-innervation of the gut / Khalil N. Bitar, Shreya Raghavan, Sita Somara, Elie Zakhem and Stephen Rego -- Genitourinary system / Mehran Abolbashari, Anthony Atala and James J. Yoo -- Clinical aspects of regenerative medicine: immune system / Erszebet Szilagyi, Premenand Sundivakkam, Tamara Nunez, Kavitha Premenand, Norma Kenyon and Amelia Bartholomew -- Development of appropriate imaging methods to trace cell fate, engraftment, and cell survival / Jesse V. Jokerst and Sanjiv S. Gambhir -- Gap analysis to target therapies / Adrian P. Gee -- Funding for the translation of regenerative medicines / Neil J. Littman, Elona Baum and Alan O. Trounson.
  • 2016 Springer
    Chao Ma, Yuguang Huang, editors.
  • 2015 Springer
    Andrew J. Krentz, Lutz Heinemann, Marcu Hompesch, editors.
    This book aims to aid the selection of the most appropriate techniques for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, and related cardiometabolic disease. Clinical research methods for assessing the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycaemic clamp technique, have become well-established in proof-of-mechanism studies; however, selection of the best techniques is by no means straightforward. This book will aid the understanding of the need for new pharmacotherapies for type 1 diabetes, type 2 diabetes, and obesity and the molecular targets of drugs currently in development. Emerging technologies including the omics disciplines are considered together with practical and ethical issues of early phase clinical trials in subjects with cardiometabolic disorders. Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development will be of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.
  • 2011 Springer
    Kristina Hug, Göran Hermerén, editors.
    For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications.
  • 2012 Springer
    Paul A. Lapchak, John H Zhang, editors.
    Pt. 1. Theoretical overview -- pt. 2. Mechanisms and targets -- pt. 3. Translational models -- pt. 4. De-risking of drug candidates -- pt. 5. Therapy delivery -- pt. 6. Therapy development -- pt. 7. Clinical trial design.
  • 2015 ScienceDirect
    Yoram Vodovotz, Gary An.
    Ch. 1.1. Interesting times: the translational dilemma and the need for translational systems biology of inflammation -- Ch. 2.1. A brief history of the philosophical basis of the scientific endeavor: how we know what we know, and how to know more -- Ch. 2.2. A brief history of biomedical research up to the molecular biology revolution -- Ch. 2.3. Biomedical research since the molecular revolution: an embarrassment of riches -- Ch. 2.4. Randomized clinical trials: a bridge too far? -- Ch. 2.5. Complexity in biomedical research: mysticism versus methods -- Ch. 2.6. Human nature, politics, and translational inertia -- Ch. 3.1. Towards translational systems biology of inflammation -- Ch. 3.2. Dynamic knowledge representation and the power of model making -- Ch. 3.3. A roadmap for a rational future: a systematic path for the design and implementation of new therapeutics -- Ch. 4.1. From data to knowledge in translational systems biology: an overview of computational approaches across the scientific cycle -- Ch. 4.2. Data-driven and statistical models: everything old is new again -- Ch. 4.3. Mechanistic modeling of critical illness using equations -- Ch. 4.4. Agent-based modeling and translational systems biology: an evolution in parallel -- Ch. 4.5. Getting science to scale: accelerating the development of translational computational models -- Ch. 5.1. What is old is new again: the scientific cycle in the twenty-first century and beyond -- Index.
  • 2012 Springer
    edited by David Abraham, Clive Handler, Michael Dashwood, Gerry Coghlan.
    Section I. Hot topics in vascular biology -- Section II. Novel molecular mediators regulating cardiovascular system -- Section III. Clinical aspects of cardiovascular disease -- Section IV. Clinical and translational aspects of pulmonary vascular disease -- Index.
  • 2006 Springer Protocols
    edited by Hydar Ali, Bodduluri Haribabu.
    Bioluminescence resonance energy transfer to monitor protein-protein interactions / Tarik Issad and Ralf Jockers -- Identification of interacting proteins using the yeast two-hybrid screen / Kelly L. Jordan-Sciutto and Marshall B. Montgomery -- Analysis of PDZ domain interactions using yeast two-hybrid and coimmunoprecipitation assays / Hyun Woo Lee, Jaewon Ko, and Eunjoon Kim -- Clustering assay for studying the interaction of membrane proteins with PDZ domain proteins / Jaewon Ko and Eunjoon Kim -- Mammalian cell microinjection assay to study the function of Rho family guanosine triphosphatases / Ritu Garg and Anne J. Ridley -- Affinity-based assay of Rho guanosine triphosphatase activation / Mary Stofega, Celine DerMardirossian, and Gary M. Bokoch -- Assay for phospholipase D in cell-free systems / Shankar S. Iyer and David J. Kusner -- Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipase D / Amanda Fensome-Green and Shamshad Cockcroft -- Analysis of global gene expression profiles activated by chemoattractant receptors / Fernando O. Martinez and Massimo Locati -- Genetic reconstitution of bone marrow for the study of signal transduction ex vivo / Martha S. Jordan -- Proteomic analysis of human neutrophils / George Lominadze ... [et al.]. Transmembrane signaling by G protein-coupled receptors / Louis M. Luttrell -- Crosstalk coregulation mechanisms of G protein-coupled receptors and receptor tyrosine kinases / Kanchana Nataranjan and Bradford C. Berk -- Protein-protein interactions in signaling cascades / Bruce J. Mayer -- Biological role of the CXCR4-SDF-1 axis in normal human hematopoietic cells / Marcin Majka and Mariusz Z. Ratajczak -- Functional expression of CXCR4 in Saccharomyces cerevisiae in the development of powerful tools for the pharmacological characterization of CXCR4 / Zi-xuan Wang, James R. Broach, and Stephen C. Peiper -- Characterization of constitutively active mutants of G protein-coupled receptors / Jean-Marc Navenot, Zi-xuan Wang, and Stephen C. Peiper -- G protein-coupled receptor dimerization and signaling / Mario Mellado ... [et al.] -- Real-time analysis of G protein-coupled receptor signaling in live cells / Venkatakrishna R. Jala and Bodduluri Haribabu -- Isolation of membrane rafts and signaling complexes / Kathleen Boesze-Battaglia -- Methods for the study of signaling molecules in membrane lipid rafts and caveolae / Rennolds S. Ostrom and Paul A. Insel --
  • 2009 Springer
    S. Shioda, I. Homma, N. Kato (eds.).
  • 2011 Thieme eNeurosurgery
    Aldo Cassol Stamm, [editor].
    "The diagnosis and treatment of the diseases of the skull base have changed dramatically in the past few years, transforming the fields of neurosurgery and otolaryngology-head and neck surgery. The increasing advances in these fields have addressed the ENT physicians and neurosurgeons to keep up with the expanding information in the exciting area of skull base. By publishing this book, we are presenting a multidisciplinary approach to the lesions of the skull base. We bring chapters written by the most experienced groups around the world with both, basic information and the latest advances in macro and surgical anatomy, radiology, anesthesia, endocrinology, and all modalities of transnasal endoscopic assisted surgical approaches to the anterior, middle, posterior, zygomatic and infra temporal fossae. In addition, the extended approaches such as to the craniocervical junction and petrous apex are also addressed. Especial emphasis is also given to the reconstruction techniques"--Provided by publisher.
  • 2013 Springer
    Rocio Garcia-Retamero, Mirta Galesic, editors.
    Recent research in health decision making has shown that many patients, even those with a college education, have difficulties grasping a host of numerical concepts, including percentages and probabilities. Yet, basic numeracy and graph literacy are essential for understanding information relevant to making decisions about health, such as the incidence and prevalence of different diseases, risk reductions from medical screenings and treatments, and risk increases from side effects of treatments and unhealthy behaviors. Patients who have problems understanding such numerical concepts are often prone to errors in risk perception and medical choices. Importantly, informed medical decision making, heavily reinforced these days by the legal requirement for informed consent, depends critically on communication of quantitative medical information. Meeting the challenge of effectively communicating medical information to patients with different levels of numeracy and graph literacy has become more important than ever. Transparent Communication of Health Risks describes a series of cross-cultural studies investigating how people in countries with different medical and educational systems understand numerical and graphical information, what they know about existing medical treatments and screenings, which presentation formats help them better understand the relevant information, and how they use the data to make medical decisions. Focusing on the careful measurement of necessary knowledge and skills, the book also includes validated numeracy and graph literacy scales in English, Spanish, and German. Some of the topics covered in the book are:numeracy and graph literacy for health;measuring risk comprehension in educated samples;communicating information about medical treatment and screening;reducing the effect of framed messages about health;the effect of individual differences on shared decision making; andtransparent health information in the media.Transparent Communication of Health Risks emphasizes the importance and value of working toward the development of tailored risk communication interventions and clarifies the tasks ahead for health psychologists, public health professionals, pharmaceutical and medical education companies, medical physicists, and nurses.
  • 2014
    Lesley A. Sharp.
    Status: Not Checked OutLane Catalog Record
    " In The Transplant Imaginary, author Lesley Sharp explores the extraordinarily surgically successful realm of organ transplantation, which is plagued worldwide by the scarcity of donated human parts, a quandary that generates ongoing debates over the marketing of organs as patients die waiting for replacements. These widespread anxieties within and beyond medicine over organ scarcity inspire seemingly futuristic trajectories in other fields. Especially prominent, longstanding, and promising domains include xenotransplantation, or efforts to cull fleshy organs from animals for human use, and bioengineering, a field peopled with "tinkerers" intent on designing implantable mechanical devices, where the heart is of special interest. Scarcity, suffering, and sacrifice are pervasive and, seemingly, inescapable themes that frame the transplant imaginary. Xenotransplant experts and bioengineers at work in labs in five Anglophone countries share a marked determination to eliminate scarcity and human suffering, certain that their efforts might one day altogether eliminate any need for parts of human origin. A premise that drives Sharp's compelling ethnographic project is that high-stakes experimentation inspires moral thinking, informing scientists' determination to redirect the surgical trajectory of transplantation and, ultimately, alter the integrity of the human form. "-- Provided by publisher.
  • 2012 Karger
    volume editors, Peter Häusermann, Jürg Steiger, Jakob Passweg.
  • 2014 ClinicalKey
    edited by John L.R. Forsythe.
    Controversies in the ethics of organ transplantation / Marc J. Clancy and Alex T. Vesey -- Organ donation in the UK : recent progress and future challenges / Christopher J. Rudge -- Immunology of graft rejection / George Tse and Lorna Marson -- Testing for histocompatibility / Phil Dyer, Ann-Margaret Little and David Turner -- Immunosuppression with the kidney as paradigm / David Wojciechowski, Gregory Veillette and Flavio Vincenti -- Preservation and perfusion of abdominal organs for transplantation / John O'Callaghan, Peter Friend and Rutger J. Ploeg -- Recent trends in kidney transplantation / Gabriel C. Oniscu -- Liver transplantation / James J. Pomposelli, Mary Ann Simpson, Caroline Simon and Elizabeth A. Pomfret -- Pancreas transplantation / Murat Akyol -- Islet transplantation / John J. Casey -- Cardiothoracic transplantation / Asif Hasan and John H. Dark -- Transplant infectious disease / Camille Nelson Kotton -- Chronic transplant dysfunction / Shikha Mehta and Roslyn B. Mannon.
  • 2013 Springer Protocols
    edited by Andrea A. Zachary and Mary S. Leffell.
    Alloreactivity / Sidonia B.G. Eckle, Jamie Rossjohn, and James McCluskey -- Antibodies in Transplantation : The Effects of HLA and Non- HLA Antibody Binding and Mechanisms of Injury / Nicole M. Valenzuela and Elaine F. Reed -- Cell Mediated Rejection / Kathryn J. Wood, Masaaki Zaitsu, and Ryoichi Goto -- Transplantation Tolerance / Colin Brinkman ... [et al.] -- Composite Tissue Transplantation / Gerald Brandacher -- Transplantation of the Sensitized Patient: Histocompatibility Testing / Robert A. Montgomery, Mary S. Leffell, and Andrea A. Zachary -- Thoracic Organ Transplantation : Laboratory Methods / Jignesh K. Patel and Jon A. Kobashigawa -- HLA Typing by Sequence-Specific Primers / Mike Bunce and Ben Passey -- Human Leukocyte Antigen (HLA) Typing by DNA Sequencing / Ana Lazaro ... [et al.] -- Next-Generation HLA Sequencing Using the 454 GS FLX System / Elizabeth A. Trachtenberg and Cherie L. Holcomb -- Chimerism Testing by Quantitative PCR Using Indel Markers / Ketevan Gendzekhadze, Laima Gaidulis, and David Senitzer -- Gene-Specific PCR Typing of Killer Cell Immunoglobulin- Like Receptors / Raja Rajalingam and Elham Ashouri -- Complement-Dependent Cytotoxicity Crossmatch / Jeremy Ryan Pena, Donna Fitzpatrick, and Susan L. Saidman -- Lymphocyte Crossmatching by Flow Cytometry / Robert A. Bray -- Solid Phase Assay Measuring C4d Deposition to Determine Complement Fixation by HLA-Specific Antibodies / John D. Smith and Marlene L. Rose -- C1q Assay for the Detection of Complement Fixing Antibody to HLA Antigens / Ge Chen and Dolly B. Tyan -- Tetramer Staining for the Detection of HLA-Specific B cells / Donna P. Lucas, Mary S. Leffell, and Andrea A. Zachary -- Flow Cytometric Crossmatch Test Using Endothelial Precursor Cells Isolated from Peripheral Blood / Annette M. Jackson, Donna P. Lucas, and Jessica L. Badders -- Detection of Antibodies to the Angiotensin II-Type 1 Receptor in Transplantation / Duska Dragun -- Detection of Antibodies to Self-Antigens (K-alpha 1 Tubulin, Collagen I, II, IV, and V, Myosin, and Vimentin) by Enzyme-Linked Immunosorbent Assay (ELISA) / Nayan J. Sarma, Venkataswarup Tiriveedhi, and T. Mohanakumar -- Cylex ImmuKnow Cell Function Assay / Adriana Zeevi and John Lunz -- Detection of Intracellular Cytokines / Nancy L. Reinsmoen and Chih-Hung Lai -- Tolerogenic Dendritic Cells and Induction of T Suppressor Cells in Transplant Recipients / George Vlad and Nicole Suciu-Foca -- Discovery and Customized Validation of Antibody Targets by Protein Arrays and Indirect ELISA / Tara K. Sigdel and Minnie M. Sarwal -- RNA Purification and Expression Analysis Using Microarrays and RNA Deep Sequencing / Steven R. Head ... [et al.].
  • 2006 Springer Protocols
    edited by Philip Hornick, Marlene Rose.
    Current status of renal transplantation / Christopher J. Callaghan and J. Andrew Bradley -- Current status of liver transplantation / Peter J. Friend and Charles J. Imber -- Current status of islet transplantation / Jonathan R.T. Lakey, Mohammadreza Mirbolooki, and A.M. James Shapiro -- Current status of lung transplantation / Allan R. Glanville -- Chronic rejection in the heart / Philip Hornick and Marlene Rose -- Direct and indirect allorecognition / Philip Hornick -- HLA typing and its influence on organ transplantation / Stephen Sheldon and Kay Poulton -- Strategies for gene transfer to solid organs: viral vectors / Charlotte Lawson -- Nonviral vectors / Louise Collins -- Detection and clinical relevance of antibodies after transplantation / John D. Smith and Marlene Rose -- Reprogramming the immune system using antibodies / Luis Graca and Hermann Waldmann -- In vitro assays for immune monitoring in transplantation / Maria P. Hernandez-Fuentes and Alan Salama -- Proteomics and laser microdissection / Emma McGregor and Ayesha DeSouza -- Real-time quantitative polymerase chain reaction in cardiac transplant research / Leanne E. Felkin, Anne B. Taegtmeyer, and Paul J.R. Barton -- Organ preservation / Mark Hicks ... [et al.] -- Pharmacological manipulation of the rejection response / Peter Mark Anthony Hopkins -- Experimental models of graft arteriosclerosis / Bezhad Soleimani and Victor C. Shi.
  • 2008 Springer
    Charles W. Hewitt and W.P. Andrew Lee, editors ; Chad R. Gordon, associate editor.
    The establishment of composite tissue allotransplantation as a clinical reality / Joseph E. Murray -- The evolution of composite tissue allotransplantation: the twentieth century realization of "Cosmas and Damian" / Chad R. Gordon ... [et al.] -- The impact of the discovery of cyclosporine on transplantation of composite tissue allografts / Zsolt T. Csapo, Bence Forgacs, and Barry D. Kahan -- The first limb transplants with cyclosporine / Christopher J. Salgado, Samir Mardini, and Charles W. Hewitt -- Translational research in composite tissue allotransplantation / Linda C. Cendales, David E. Kleiner, and Allan D. Kirk -- Relative antigenicity of allograft components and differential rejection / Jignesh Unadkat ... [et al.] -- On the road to tolerance induction in composite tissue allotransplantation / Mark A. Hardy -- Donor-specific tolerance / Au H. Bui, Gerald Lipshutz, and Jerzy Kupiec-Weglinski -- Immune tolerance induction: basic concepts for composite tissue allotransplantation / Patricio Andrades, Clement Asideu, and Judith M. Thomas -- Allograft survival with calcineurin inhibitors / Neil F. Jones and Esther Voegelin -- Long-term prevention of rejection and combination drug therapy / Thomas H. Tung -- Locoregional immunosuppression in composite tissue allografting / Scott A. Gruber -- New approaches to antibody therapy / Dalibor Vasilic, Moshe Kon, and Cedric G. Francois -- World experience of hand transplantation-independent assessment / W.P. Andrew Lee, Justin M. Sacks, and Elaine K. Horibe -- Hand transplantation: Lyon experience / Palmina Petruzzo ... [et al.] -- Hand transplantation: the Louisville experience / Vijay S. Gorantla and Warren C. Breidenbach III -- Hand transplantation: the Innsbruck experience / Stefan Schneeberger, Marina Ninkovic, and Raimund Margreiter -- Vascularized bone marrow transplantation / Chau Y. Tai ... [et al.] -- Vascularized bone marrow transplantation: pathology of composite tissue transplantation-induced graft-versus-host-disease / Rajen Ramsamooj and Charles W. Hewitt -- Immune cell redistribution after vascularized bone marrow transplantation / Waldemar L. Olszewski and Marek Durlik -- Vascularized knee transplantation / Michael Diefenbeck and Gunther O. Hofmann -- Tracheal transplantation / Gabriel M. Marta and Walter Klepetko -- Laryngeal transplantation / Robert R. Lorenz and Marshall Strome -- Face transplantation / Maria Siemionow and Galip Agaoglu -- The role of allografts in lower extremity reconstruction / Milton B. Armstrong, Ricardo Jimenez-Lee, and Eddie Manning -- Skin allografts in scalp reconstruction / Peter C. Neligan -- Abdominal wall transplantation / Chau Y. Tai and Susan E. Mackinnon -- Live-donor nerve transplantation / Scott A. Gruber and Pedro Mancias -- Ethical and policy concerns of hand/face transplantation / Rhonda Gay Hartman -- Ethical debate on human face transplantation / François Petit -- Psychosocial issues in composite tissue allotransplantation / Barckley Storey ... [et al.] -- Composite tissue transplantation in the twenty-first century / Kirby S. Black and Charles W. Hewitt.
  • 2006 Springer
    Antal Nógrádi.
    Anatomy and physiology of the spinal cord / Antal Nógrádi and Gerta Vrbová -- Recovery of function after spinal cord injury / Gavin Clowry and Urszula Slawinska -- Recovery of lost spinal cord function by facilitating the spinal cord circuits below the lesion / Urszula Slawinska -- Encouraging regeneration of host neurones: the use of peripheral nerve bridges, glial cells or biomaterials / Antal Nógrádi -- Encouraging regeneration of host neurons: transplantation of neural tissues into the injured spinal cord grafts of embryonic neural tissue / Gerta Vrbová -- Replacement of specific neuronal populations in the spinal cord / Antal Nógrádi -- Replacement of specific populations of cells: glial cell transplantation into the spinal cord / Antal Nógrádi.
  • 2015 ClinicalKey
    Ronald W. Busuttil, Goran B. Klintmalm.
    Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-date guidance on every imaginable aspect of liver transplantation. Understand today's full range of transplantation techniques with complete step-by-step descriptions of each, and access the background information and management options for each hepatic disease entity. Take advantage of detailed discussions of everything from pathophysiology and patient and donor selection, to transplantation anesthesia and operative procedures; immunosuppression; postoperative care; and ethical issues.
  • 2013 ScienceDirect
    edited by Sid M. Becker, Andrey V. Kuznetsov.
    Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible. Provides detailed mathematical model development to interpret experiments and provides current modeling practices Provides a wide range of biological and clinical applicationsIncludes physiological descriptions of models.
  • 2013 Springer
    Yuichi Sugiyama, Bente Steffansen, editors.
    Transporters in Drug Development is a corner stone in a high profile book series on advances in pharmaceutical sciences initiated by AAPS, Springer and Professor Daan Crommelin as series Editor. Transporters in Drug Development: Discovery, Optimization, Clinical Study and Regulation list chapters written by leading researchers in the transporter field from academia, pharmaceutical industry and medicines agencies. The book encompasses examples and advises on how membrane transporters can be dealt with in academic industrial drug discovery and pharmaceutical development as well as from a regulatory perspective. Methods and examples of in vitro characterization of single transporters in intestine, liver and kidney are described as well as characterization of substrate overlap between various transporters. Furthermore, probes and biomarkers are suggested for studies of the transporters impact on the pharmacokinetics of drug substrates/candidates interacting on transporters. The challenges of translating in vitro observed interaction of transporters into in vivo relevance are discussed as well as the perspectives of applying targeted proteomics and mechanistic modelling in this process.
  • 2009 Springer
    volume editors, Dirk-Henner Lankenau, Jean-Nicolas Volff.
  • 2010 ClinicalKey
    [edited by] Edward R. Laws, Giuseppe Lanzino.
    Transsphenoidal Surgery, by Drs. Laws and Lanzino, captures all of today's clinical knowledge on the multidisciplinary management of pituitary tumors, with a focus on surgical techniques. Acclaimed international experts bring you detailed guidance on natural history, radiologic and clinical aspects, surgical indications, and resection techniques. What₂s more, case presentations and clinical photographs help you reduce the risk of error and advance your own surgical skills. At expertconsult.com, you'll have online access to the full text plus streaming videos of key procedures to help you provide the best possible outcomes for every patient. Access the fully searchable text online at expertconsult.com and view hours of videos in which experts demonstrate how to perform key procedures. Refine your skills through discissions of intraoperative imaging, new techniques in transsphenoidal surgery, new microsurgical procedures, radiosurgical techniques, and more. Get balanced and comprehensive perspectives on pituitary surgery from well-recognized international, multidisciplinary contributors. Make better-informed decisions with case presentations, drawn from Dr. Laws's 40 plus years as a leader in pituitary surgery, that include a summary of the clinical history, preoperative radiographs, and postoperative clinical information and radiographs. Tap into exceptional visual guidance and reduce the risk of error through abundant clinical photographs, line drawings, and procedural videos. Find the information you need quickly via a consistent chapter-to-chapter organization.
  • 2010
    Lynn Wanshu Sun.
    The eyeblink is one of the most basic motor behaviors and has served as a longstanding model for the study of adaptive and associative forms of motor conditioning. However, cerebellar pathways that support blinking behaviors remain poorly studied in the mouse, an increasingly popular animal model for motor learning. The precise location of eyeblink-related neurons is poorly defined, particularly in the red nucleus and the cerebellar nuclei and cortex. To pinpoint these neurons, I injected the GFP-expressing retrograde transsynaptic viral tracer Pseudorabies (PRV-152) into the orbicularis oculi muscle in the eyelids of live C57Bl6 mice. PRV travels retrograde across multiple synapses in the motor pathway and infects cells ultimately projecting to the injection site. By registering anatomical sites of the virally labeled cells, I created detailed maps of neurons presumably involved in controlling blink-related behavior. In the facial nucleus, viral labeling was strictly ipsilateral to the injection site and restricted to the dorsolateral rostral segment. The red nucleus is bilaterally labeled at the lateral rim with heavier labeling in the contralateral nucleus. Labeling was bilaterally distributed across all three deep cerebellar nuclei. In the cerebellar cortex, a characteristic spatiotemporal pattern was observed. Posterior vermal and floccular Purkinje cells were labeled first, followed by mid- and anterior vermal cells, and finally cells in the hemispheric Crus 1/2 and Simple lobules. Based on these results, I hypothesized that PRV injections into the eyelid uncover multiple distinct, cerebellar-modulated motor output pathways. These pathways have not previously been explored in the mouse; additionally, several of the putative pathways were poorly defined in other model systems as well. This hypothesis was then tested with single-step retrograde tracings from each of the deep cerebellar nuclei. The following circuits were confirmed: 1) from the ansiform lobule to the dentate nucleus 2) from the simple lobule to the anterior interpositus nucleus 3) from the anterior vermal and paravermal cerebellar cortex to the posterior interpositus nucleus, and 4) from the posterior vermis and paravermis to the fastigial nucleus. In prior literature, pathways 1 and 2 have been implicated in classical conditioning, and pathway 3 in cerebellar modulation of reflex blinks. Based on circuit analysis, pathway 4 is putatively associated with eye-eyelid coordination, but there is little existing research on this possibility. To complete my investigation of the mouse cerebellar eyeblink circuit, I traced anterograde from the vestibular nucleus to the red nucleus and retrograde from the red nucleus to the vestibular nucleus, establishing the existence of a previously unexplored vestibulorubral pathway in the mouse which may serve as the output circuit of pathway 4. As a whole, this body of work explores the location and distribution of eyeblink-related neurons in the mouse, identifies multiple parallel motor circuits in the mouse cerebellum, and offers evidence toward functional organization of the cerebellum.
  • 2011 Springer
    Maria Grazia Bongiorni, editor ; foreword by Bruce L. Wilkoff.
  • v. 1, 1940.
    Cea, Leopoldo,.
    Status: Not Checked OutLane Catalog Record
    1. Análisis de la sangre.
  • 1944-
    Pérez Fontana, Velarde.
    Status: Not Checked OutLane Catalog Record
    v. 1., fasc. 1. Echinococcus granulosus.
  • 2009 Springer
    Santi Centorrino ... [et al.].
  • [v. 1, 5], [1833, 1839]
    Giacomandrea Giacomini.
    Status: Not Checked OutLane Catalog Record
  • 2008 Ovid
    editors, Lewis Flint ... [et al.].
  • 2007 Springer
    M.Y.H. Bangash ... [et al.].
  • 2015 Springer
    Meryam Schouler-Ocak, editor
    Introduction -- The Relevance of Trauma in Immigrants -- Cross-cultural Communication with Traumatised Immigrants -- Cross-cultural Competence in Handling with Traumatised Immigrants -- Clinical Diagnostic of Traumatised Immigrants -- Treatment Process of Traumatized immigrant Children and Adolescent -- Trauma-centered Therapy with EMDR -- Refugees and Asylum Seeker and Trauma -- Expert Opinion of Traumatised Immigrants -- Injured Helper -- Immigrants in an Outpatient Clinic for Traumatised Immigrants -- Cross-cultural Psychotherapy with Immigrants from Operational Zone -- Therapy Concept for Traumatised Refugees in Denmark -- Rethinking Trauma as a Global Challenge.
  • 2015 Springer
    Nick G. Lasanianos, Nikolaos K. Kanakaris, Peter V. Giannoudis, editors.
    Reporting on classification systems which are currently utilised in the clinical setting, this illustrated guide is an essential resource for all young clinicians and researchers of Trauma and Orthopaedics. Each chapter of the different anatomical sites and pathologies is designed to assist the decision making of the readers regarding treatment strategy as well as informed consent of their patients. Trauma and Orthopaedic Classifications: A Comprehensive Overview includes classifications relevant to both Elective Orthopaedic Practice and Orthopaedic Trauma. Clear graphic illustrations accompany the description of all different classification schemes in a comprehensive manner, together with a structured presentation of existing clinical evidence. Surgeons in training right through to senior surgeons and academic clinicians will find this book to be a key reference to formulate the right decisions in their clinical practice.
  • 2015 Cambridge
    edited by Charles E. Smith.
  • 2007 Springer
    Kai-Uwe Schmitt ... [et al.].
  • 2008 ClinicalKey
    [edited by] Roy Sanders.
    This volume delivers broad, practical knowledge of trauma diagnosis and management in a high-yield format that enables quick mastery of the material. A consistent organization by body region, summary tables and boxes, bulleted lists, and detailed artwork make this reference perfect for quick review of the essential knowledge.
  • 2013 Springer
    K. Mohan Iyer, editor.
    Trauma Management in Orthopedics has been written to serve as a general introduction to the field of trauma in the field of orthopedics. It is composed of a number of commonly seen disorders and with a corresponding therapeutic pathway, clearly explained with numerous xrays and diagrams to aid the reader in their understanding of these useful procedures.The book is intended as a basic resource for trainees and junior surgeons, but will also be useful to more experienced specialists who require an easy to follow clinical guide to assist in day to day practice of orthopedic trauma management.
  • 2008 Ovid
    [edited by] Andrew B. Peitzman ... [et al.].
    Also available: Print – 2008
  • 2013 Ovid
    Andrew B. Peitzman ... [et al.].
    Also available: Print – 2013
  • 2014 Springer
    edited by S. Di Saverio, G. Tugnoli, F. Catena, L. Ansaloni, N. Naidoo.
    Trauma surgery has increasingly become a specialized field inspired by different principles and philosophy. A good trauma surgeon is a surgeon who knows how to perform abdominal, vascular, thoracic, urologic, gynecologic, and orthopaedic procedures and is able to repair multiple traumatic injuries in the best sequence possible. In this second volume the focus is exclusively on thoracic and abdominal trauma, with coverage of injuries to all regions. The surgical techniques employed in managing such trauma are carefully described with the aid of high-quality illustrations. Exploratory surgery (via either laparotomy or laparoscopy), damage control surgery, and definitive surgery are all fully covered, and attention is drawn to important technical tips and tricks. The volume will be a handy pocket guide for trainee surgeons who are beginning to deal with severe multiple trauma patients, as well as for all general or specialty surgeons and professionals (including scrub nurses and theatre staff) who are involved in trauma care and wish to keep abreast of developments in this complex field.
  • 2014 Springer
    S. Di Saverio, G. Tugnoli, F. Catena, L. Ansaloni, N. Naidoo, editors ; foreword by Zsolt J. Balogh.
    Trauma surgery has increasingly become a specialized field inspired by different principles and philosophy. A good trauma surgeon is a surgeon who knows how to perform abdominal vascular, thoracic, urologic, gynecologic, and orthopaedic procedures and is able to repair multiple traumatic injuries in the best sequence possible. In this first volume, practical, up-to-date guidance is provided on the optimal critical care and ICU management of trauma patients. In addition, individual chapters focus on specific injuries in orthopaedic trauma (and especially spinal trauma) and neurotrauma, with the aim of providing a fresh view of the surgical approach and practical suggestions for improving the skills of treating surgeons. Educational issues and the organization of a trauma center are also covered. The volume will be a handy pocket guide for trainee surgeons and any surgeon, physician, or nurse who treats trauma patients. It will be particularly relevant for emergency department physicians, critical care and ICU doctors, orthopaedic surgeons, neurosurgeons, and professionals responsible for trauma care and decision making, programs of trauma education, or organization of a trauma center.
  • 2016 Springer
    Lawrence M. Gillman, Sandy Widder, Michael Blaivas, Dimitrios Karakitsos, editors.
    This is the first book exploring the unique dynamics created by a multidisciplinary trauma team and how crisis management strategies can improve teamwork and communication and, potentially, improve patient resuscitation outcomes. Crisis resource management (CRM) is integral to the way that we manage ourselves, team members, and patients during emergency situations. It is essentially the ability to translate knowledge of what needs to be done into effective actions during a crisis situation. Building on the revolutionary American College of Surgeons Advanced Trauma Life Support (ATLS®) course, Trauma Team Dynamics illustrates the integration of the principles of CRM to team dynamics throughout the resuscitation ? from the scene, through pre-hospital care and transport, to the trauma bay, and finally to definitive care and beyond. The editors and contributors are international experts in trauma, critical care, emergency medicine, nursing, respiratory therapy, and pre-hospital care and include NASA- and United States military-affiliated experts. Trauma Team Dynamics is intended for use as both a day-to-day clinical resource and a reference text, and includes self-assessment questions as well as guidance on CRM curriculum design and implementation.
  • 2008
    editors, David V. Feliciano, Kenneth L. Mattox, Ernest E. Moore.
    Status: Not Checked OutLane Catalog Record
  • 2013 AccessSurgery
    editors, Kenneth L. Mattox, Ernest E. Moore, David V. Feliciano.
    Kinematics -- Epidemiology -- Injury prevention -- Trauma systems, triage, and transport -- Injury severity scoring and outcomes research -- Acute care surgery -- Prehospital care -- Disaster and mass causalty -- Rural trauma -- Initial assessment and management -- Airway management -- Management of shock -- Postinjury hemotherapy and hemostasis -- Emergency department thoracotomy -- Diagnostic and interventional radiology -- Surgeon-performed ultrasound in acute care surgery -- Principles of anesthesia and pain management -- Infectons -- Injury to the brain -- Eye -- Face -- Neck -- Vertebrae and spinal cord -- Trauma thoracotomy: principles and techniques -- Lung, trachea, and esophagus -- Heart and thoracic vascular injuries -- Trauma laparotomy: principles and techniques -- Diaphragm -- Liver and biliary tract -- Injury to the spleen -- Stomach and small bowel -- Doudenum and pancreas -- Colon and rectal trauma -- Abdominal vascular injury -- Pelvis -- Genitourinary trauma -- Trauma in pregnancy -- Trauma damage control -- Upper extremity -- Lower extremity -- Periphearl vascular injury -- Alcohol and drugs -- The pediatric patient -- The geriatric patient -- Ethics of acute care surgery -- Social violence -- Wounds, bites, and stings -- Burns and radiation -- Temperature-related syndromes: hyperthermia, hypothermia, and frostbite -- Organ procurement for transplantation -- Rehabilitation -- Modern combat casualty care -- Genomics and acute care surgery -- Trauma, medicine, and the law -- Principles of critical care -- Cardiovascular failure -- Respiratory insufficiency -- Gastrointestinal failure -- Renal failure -- Nutritional support and electrolyte management -- Multiple organ failure.
  • 2012 Cambridge
    edited by Cristina Morganti-Kossmann, Ramesh Raghupathi, Andrew Maas
    Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.
  • 2010 CRCnetBASE
    edited by Mark J. Ashley.
  • 2012 Springer
    edited by Jack W. Tsao.
    Overview of TBI / David F. Moore, Michael S. Jaffee, Geoffrey Ling -- Imaging diagnosis of TBI / Tuong H. Le, Shirley I. Stiver, Alisa D. Gean -- Neurocognitive assessment of mTBI / W. Huw Williams, Seb Potter, Helen Ryland, Philip Yates, James Tonks & Adam Reuben -- Management of moderate and severe TBI / Scott A. Marshall, Randy Bell, Rocco A. Armonda, Geoffrey S.F. Ling -- Sports concussion / Sharon R. Weeks, Jack W. Tsao -- Blast-related concussion / Carson Lawall -- Sleep/wake disturbances in mild traumatic brain injury patients / Michael Russo, Aimee Alphonso, Ian Murphy -- Vestibular consequences of mTBI / Michael E Hoffer, Kim Gottshall, Erik S. Viirre -- Post-traumatic headache / Jay C. Erickson, Brett J. Theeler -- Seizures after TBI / John Betjemann, Karen Parko -- Endocrine disturbances following TBI / Victoria Tepe, Arthur Guerrero -- Confronting mild TBI and Co-occurring PTSD symptoms in combat deployed service members / Justin S. Campbell, Jeffrey H. Greenberg, Jennifer M. Weil -- Behavioral and psychiatric comorbidities of TBI / Robert L. Collins, Nicholas J. Pastorek, Andra L. Teten, Thomas A. Kent -- Rehabilitation of TBI / Mel Glenn -- Interventions to improve cognitive functioning after TBI / Anthony J.-W. Chen, Tatjana Novakovic-Agopian -- Current diagnostic and therapeutic challenges / Donald W. Marion.
  • pt. 1-2, 2015 ScienceDirect
    pt. 2 ScienceDirect
    edited by Jordan Grafman, Andres M. Salazar.
    The Handbook of Clinical Neurology volume on traumatic brain injury (TBI) provides the reader with an updated review of emerging approaches to traumatic brain injury (TBI) research, clinical management and rehabilitation of the traumatic brain injury patient. Chapters in this volume range from epidemiology and pathological mechanisms of injury, and neuroprotection to long-term outcomes with a strong emphasis on current neurobiological approaches to describing the consequences and mechanisms of recovery from TBI. The book presents contemporary investigations on blast injury and chronic traumatic encephalopathy, making this state-of-the-art volume a must have for clinicians and researchers concerned with the clinical management, or investigation, of TBI.
  • 2013 Springer
    E. Carlos Rodríguez-Merchán, editor.
    Distal femoral fractures -- Tibial plateau fractures -- Patellar fractures -- Patellar dislocations and osteochondral fractures -- Traumatic knee dislocation -- Floating knee -- Nonunion and malunion around the knee -- Knee extensor mechanism injuries -- Anterior cruciate ligament (ACL) injuries -- Runner's knee and pataellar tendinopathy.
  • 2014 Thieme Book
    Professor Gert Krischak.
    "Treatment of traumatic injuries is increasing in importance for physical therapists active in hospitals and private practice. In addition to the bone, joint, and soft tissue injuries incurred in sports, physical therapists are seeing more and more traumas associated with aging and with high-speed accidents. This great variety of injury types increases the complexity of treatment. Moreover, in recent years there has been a growing demand for the most complete restoration possible of both physical and psychological function. This is the principal objective of aftercare. Accordingly, this book focuses on a comprehensive presentation of individual injuries and their effect on function, as well as the guidelines and potential results of physical therapy treatment. It is addressed to students, practitioners, and teachers of physical therapy who must master and apply an understanding of the whole range of injuries, their consequences, and their treatment. "--Provided by publisher.
  • v. 1-2, 1926-28.
    Marie, Pierre.
    Status: Not Checked OutLane Catalog Record
  • 2008 ClinicalKey
    edited by Elaine C. Jung, Christopher Sanford.
    Here₂s a handy, portable guide to preventing, evaluating, and managing diseases that can be acquired in tropical environments and foreign countries! Whether you₂re a physician, traveler, or both, this respected manual is your perfect source for quick, easy access to the latest travel medicine information. New updates and additional material are presented in a sleek new design that offers rapid access to the content you need. The fourth edition features more critical content than ever before--including new evidence-based recommendations and new maps and illustrations. From pre-travel advice and immunizations to the diagnosis and treatment of a full range of travel-related illnesses, you₂ll have all the information you need to avoid, recognize, and treat illnesses acquired away from home in a convenient, pocket size guide. Illustrates key concepts with visual guidance from dynamic new images. Offers evidence-based treatment recommendations to enable you to manage diseases confidently. Provides access to need-to-know information quickly in a convenient, pocket size for excellent portability. Features 7 major sections, color-coded for quick answers: Pre-travel Advice Advice for Special Travelers Fever Diarrhea Skin Lesions Sexually Transmitted Diseases Worms.
  • 2013 ClinicalKey
    edited by Jay S. Keystone [and others].
    This 3rd Edition, by Jay S. Keystone, Phyllis E. Kozarsky, David O. Freedman, Hans D. Nothdruft, and Bradley A. Connor, prepares you and your patients for any travel-related illness they may encounter. Consult this resource for best practices on everything from immunizations and pre-travel advice to essential post-travel screening. From domestic cruises to far-flung destinations, this guide offers a wealth of practical guidance on all aspects of travel medicine. New to this edition: Effectively protect your patients before they travel with new information on immunizations and emerging and re-emerging disease strains, including traveler's thrombosis. Update your knowledge of remote destinations and the unique perils they present. Stay abreast of best practices for key patient populations, with new chapters on the migrant patient, humanitarian aid workers, medical tourism, and mass gatherings, as well as updated information on pediatric and adolescent patients.
  • 2015
    [edited by] Hans Steiner, with Rebecca Hall.
    Status: Not Checked OutLane Catalog Record
    General principles / Hans Steiner, Rebecca Hall, Julia Huemer -- Disruptive behavior disorders / Whitney Daniels, Michael Kelly, Kathleen Ares, Katie Kaszynski, Niranjan Karnik -- Attention-deficit/hyperactivity disorder (ADHD) / Michael Kelly -- Learning and executive cognitive functions / Ahmed Khan, Brianna Bendixsen, Lynne Baldwin, Diana Barrett, Richard Abbey.
  • 2009 Springer
    Zipora Shechtman.
    Intends to conceptualize aggression as a symptom of underlying behavioural and emotional problems and examines the psychology of perpetrators and the power dynamics that foster intentionally hurtful behaviour in young people. This book details how bibliotherapy offers relevant treatment and can be implemented with individuals and groups.
  • 2009 Springer
    edited by Johnny L. Matson, Frank Andrasik, Michael L. Matson.
    History of treatment in children with developmental disabilities and psychopathology / Jonathan Wilkins and Johnny L. Matson -- Applied behavior analysis and the treatment of childhood psychopathology and developmental disabilities / Joel E. Ringdahl and Terry S. Falcomata -- Cognitive behavior therapy / Ellen Flannery-Schroeder and Alexis N. Lamb -- Parent-training interventions / Nicholas Long, Mark C. Edwards, and Jayne Bellando -- Conduct disorders / Christopher T. Barry ... [et al.] -- Treatment of Attention-deficit/hyperactivity disorder (ADHD) / Ditza Zachor, Bart Hodgens, and Cryshelle Patterson -- PTSD, anxiety, and phobia / Thompson E. Davis III -- Treatment strategies for depression in youth / Martha C. Tompson and Kathryn Dingman Boger -- Medication treatment of bipolar disorder in developmentally disabled children and adolescents / Zinoviy A. Gutkovich and Gabrielle A. Carlson -- Treatment of autism spectrum disorders / Mary Jane Weiss, Kate Fiske, and Suzannah Ferraioli -- Treatment of self-injurious behaviour in children with intellectual disabilities / Frederick Furniss and Asit B. Biswas -- Communication, language, and literacy learning in children with developmental disabilities / Erna Alant, Kitty Uys, and Kerstin Tönsing -- Eating disorders / David H. Gleaves, Janet D. Latner, and Suman Ambwani -- Treatment of pediatric feeding disorders / Cathleen C. Piazza, Henry S. Roane, and Heather J. Kadey.
  • 2012
    Zhaoqing Ding.
    Microglia are the resident tissue macrophages of the central nervous system (CNS) parenchyma. While less than 20% of the cellular composition of the CNS is made up of by microglia, they play many roles in the CNS ranging from tissue remodeling, maintenance and repair to protecting the CNS against insults, both foreign- and self-derived. It is not surprising that microglia dysfunction has been shown to contribute to major neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Multiple Sclerosis (MS) as well ass [sic] lesser-known diseases such as Nasu-Hakola disease. Unfortunately, the ability to modulate microglia to beneficially modify neurodegenerative diseases remains limited. This dissertation illustrates how an antiviral and a hypertension medication ameliorate disease in animal models of neuroinflammation and neurodegeneration by modulating the cellular and molecular functions of microglia.
  • 2012 Springer
    Lee E. Ponsky (editor-in-chief) ; Donald B. Fuller, Robert M. Meier, C-M Charlie Ma (co-editors).
  • 2007 Springer
    Harold C. Urschel, Jr. (editor-in-chief) ; John J. Kresl ... [et al.] ; foreword by E. Thomson.
    Also available: Print – 2007
  • Google Books
    Hutchison, Joseph Chrisman.
    Also available: Print – 1904.
  • Google Books
    tr. from the French by a physician.
    Also available: Print – 1859-
  • v. 1-2, 1876. Google Books
    Fulltext (v. 2) Google Books
    Playfair, W. S.
    Also available: Print – v. 1-2, 1876.
  • 2012 Springer
    Henry M. Staines, Sanjeev Krishna, editors.
    Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.
  • v. 1-6, 1930-48.
    Beckman, Harry.
    Status: Not Checked OutLane Catalog Record
  • ebrary
    James Lock, Daniel Le Grange ; foreword by Gerald Russell.
    "This indispensable manual presents the Maudsley method, the leading family-based treatment for adolescents with anorexia nervosa (AN). What sets this approach apart is the central role played by parents throughout treatment. The authors are prominent experts who describe how to mobilize families to promote the patient's weight restoration and healthy eating, improve parent-child relationships, and get adolescent development back on track. Each phase of therapy is described in session-by-session detail. In-depth case illustrations show how to engage clients while flexibly implementing the validated treatment procedures"-- Provided by publisher.
  • 2013
    prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by Duke Evidence-based Practice Center ; investigators, Sana M. Al-Khatib, Nancy Allen Lapointe, Ranee Chatterjee, Matthew J. Crowley, Matthew E. Dupre, David F. Kong, Renato D. Lopes, Thomas J. Povsic, Shveta S. Raju, Bimal R. Shah, Andrzej Kosinski, Amanda J. McBroom, Megan M. Chobot, Rebecca Gray, Gillian D. Sanders.
    OBJECTIVES: There are two generally accepted strategies for managing atrial fibrillation (AF): rate control and rhythm control. However, within each strategic approach there are a large number of potential pharmacological and nonpharmacological therapies, and the comparative safety and effectiveness of these therapies--both within and between strategies--are uncertain. DATA SOURCES: We searched PubMed(r), Embase(r), and the Cochrane Database of Systematic Reviews for relevant English-language comparative studies. REVIEW METHODS: Two investigators screened each abstract and full-text article for inclusion, abstracted data, rated quality and applicability, and graded evidence. When possible, random-effects models were used to compute summary estimates of effects. RESULTS: Our review included 182 articles (148 unique studies): 14 studies relevant to rate-control drugs, 3 relevant to strict versus lenient rate control, 6 relevant to rate-control procedures versus drugs in patients for whom initial pharmacotherapy was ineffective, 42 relevant to antiarrhythmic drugs and electrical cardioversion for conversion to sinus rhythm, 83 relevant to rhythm-control procedures and drugs for maintenance of sinus rhythm, and 14 focusing on the comparison of rate- and rhythm-control strategies. Our ability to draw conclusions for the Key Questions addressing rate-control strategies was limited by the small number of available studies that assessed comparable therapies and outcomes, although we found a high strength of evidence for consistent benefit of calcium channel blockers (verapamil or diltiazem) compared with digoxin for ventricular rate control. For comparisons of methods for electrical cardioversion for conversion to sinus rhythm, there was high strength of evidence that use of a single biphasic waveform was more effective than use of a single monophasic waveform (odds ratio [OR] 4.39; 95% confidence interval [CI], 2.84 to 6.78) and that a 200 Joules (J) biphasic shock was less effective than a 360 J monophasic shock (OR 0.16; 95% CI, 0.05 to 0.53). Drug enhancement of external electrical cardioversion demonstrated a benefit compared with no drug enhancement (moderate strength of evidence), but data evaluating whether any one antiarrhythmic agent was more effective than others at restoring sinus rhythm were inconclusive. Our review found high strength of evidence supporting pulmonary vein isolation (PVI) versus antiarrhythmic drugs for maintenance of sinus rhythm in a select subset of patients (those with paroxysmal AF who were younger and with no more than mild structural heart disease; OR 6.51; 95% CI, 3.22 to 13.16) and moderate strength of evidence for adding a surgical Maze procedure at the time of other cardiac surgery (specifically mitral valve surgery) as opposed to mitral valve surgery alone (OR 5.80; 95% CI, 1.79 to 18.81). Comparing rate- and rhythm-control strategies, there was moderate strength of evidence supporting comparable efficacy with regard to all-cause mortality (OR 1.34; 95% CI, 0.89 to 2.02); cardiovascular mortality (OR 0.96; 95% CI, 0.77 to 1.20); stroke (OR 0.99; 95% CI, 0.76 to 1.30); and bleeding events (OR 1.10; 95% CI, 0.87 to 1.38). Cardiovascular hospitalizations were lower with rate-control strategies than with rhythm-control strategies (OR 0.25; 95% CI, 0.14 to 0.43; high strength of evidence). We were unable to conclude whether treatment effects varied by patient characteristics due to the paucity of studies that focused on specific patient subgroups. CONCLUSIONS: In assessing clinical outcomes associated with rate- versus rhythm-control strategies, our review of recent evidence agrees with prior reviews demonstrating little overall difference in outcomes between these two strategic approaches. Uncertainties still exist within specific subgroups of interest, among the wide variety of pharmacological and procedural therapies within each strategic approach, and in the impact of strategies on long-term clinical outcomes. Specifically, our review highlights the need for additional studies evaluating final outcomes such as mortality, stroke, and cardiovascular hospitalizations.
  • 2015 Springer
    Bilal Chughtai, Alexis E. Te, Steven A. Kaplan, editors.
    Treatment of Benign Prostatic Hyperplasia: Modern Techniques is an up-to-date review of modern techniques used to treat benign prostatic hyperplasia. It provides a comprehensive review of both office and operating room based techniques. Both electrosurgical and laser based techniques are covered.These include high powered 532 nm laser photoselective laser vaporization of the prostate (PVP), holmium laser enucleation/ablation of the prostate (HoLEP/HoLAP), and Bipolar Electrovaporization of the Prostate (Bipolar EVP/Bipolar TURP). In addition, a comprehensive review of office based techniques and future therapies currently being developed is presented. Each of these techniques are presented in a balanced fashion with a focus on modern literature. Treatment of Benign Prostatic Hyperplasia: Modern Techniques will be of great value to Urologists, Urology Residents, Iternists, and Family Practitioners.
  • 2009 Springer
    Per-Ulf Tunn (ed.).
    Also available: Print – 2009
  • 2015 Springer
    edited by Timothy R. Deer, Michael S. Leong, Albert L. Ray.
    1. Pain as a Perceptual Experience -- 2. Neuroplasticity, Sensitization, and Pain -- 3. Muscle Pain Treatment -- 4. Addictive Disorders and Pain -- 5. The "Five-Minute" Mental Status Examination of Persons with Pain -- 6. The Psychological Assessment of Patients with Chronic Pain -- 7. Psychological Therapies -- 8. Billing Psychological Services for Patients with Chronic Pain -- 9. Hypnosis and Pain Control -- 10. Acupuncture -- 11. Manual Therapies -- 12. Treatment of Chronic Painful Musculoskeletal Injuries and Diseases with Regenerative Injection Therapy (RIT): Regenerative Injection Therapy Principles and Practice -- 13. Interdisciplinary Functional Restoration and Pain Programs -- 14. Pain and Spirituality -- 15. Pain Disparity: Assessment and Traditional Medicine -- 16. Sleep and Chronic Pain -- 17. Empowerment: A Pain Caregiver?s Perspective -- 18. Patient and Caregiver?s Perspective -- 19. Pain Medicine in Older Adults: How Should It Differ? -- 20. Pain Medicine and Primary Care: The Evolution of a Population-Based Approach to Chronic Pain as a Public Health Problem -- 21. Pain Care Beyond the Medical Practice Office: Utilizing Patient Advocacy, Education, and Support Organizations -- 22. Neonatal Pain -- 23. Assessing Disability in the Pain Patient -- 24. The Double Effect: In Theory and in Practice -- 25. Failure to Treat Pain.
  • 2015 Springer
    Timothy R. Deer, editor-in-chief, Michael S. Leong, associate editor-in-chief, Asokumar Buvanendran, Philip S. Kim, Sunil J. Panchal, associate editors.
  • 2015 Springer
    Timothy R. Deer, editor-in-chief, Michael S. Leong, associate editor-in-chief, Vitaly Gordin, associate editor.
    1. A Survey of Systems Involved in Nociceptive Processing -- 2. Pharmacogenomics of Pain Management -- 3. Nonsteroidal Anti-inflammatory Drugs -- 4. The Role of Antidepressants in the Treatment of Chronic Pain -- 5. Anticonvulsant Medications for Treatment of Neuropathic and "Functional" Pain -- 6. NMDA Receptor Antagonists in the Treatment of Pain -- 7. Role of Muscle Relaxants in the Treatment of Pain -- 8. Topical Analgesics -- 9. Sleep Aids -- 10. Clinical Use of Opioids -- 11. Opioid Adverse Effects and Opioid-Induced Hypogonadism -- 12. Acute Management of the Opioid-Dependent Patient -- 13. Opioids and the Law -- 14. Methadone for Chronic Pain -- 15. Toxicology Screening for Opioids -- 16. Monitoring Drug Use and Abuse: The Evolution of a Paradigm -- 17. Polypharmacy and Drug Interaction -- 18. Role of Cannabinoids in Pain Management -- 19. The Future of Pain Pharmacotherapy.
  • 2012 Springer
    Marie Lodén, Howard I. Maibach, editors.
    Development of moisturizers is a scientific and artistic discipline, where consumer insights are also needed. This new book bridges the gap between the moisturizers and the skin by covering all the essential information required to tailor the use of moisturizers to particular disorders and patients. Important aspects of skin biochemistry and barrier function are explained, and the ingredients and treatment effects of moisturizers are explored in depth. Careful attention is paid to controversies, including the role of certain moisturizers in inducing dryness/eczema, asthma, and comedones. The information provided in this unique book will enable the reader to go beyond the traditional thinking regarding skin care. The novel insights offered will suggest the properties required for a new generation of moisturizing treatments that more effectively improve the quality of life.
  • 1990-
    Early Breast Cancer Trialists' Collaborative Group (EBCTCG).
    Status: Not Checked OutLane Catalog Record
    v. 1. Worldwide evidence 1985-1990.
  • 2010 ClinicalKey
    edited by Margo Maine, Beth Hartman McGilley, Douglas W. Bunnell.
    I. Bridging the Gap : The Overview -- -- A perfect biopsychosocial storm : gender, culture, and eating disorders / Margo Maine and Douglas W. Bunnell -- What's weight go to do with it? Weight neutrality in the health at every size paradigm and its implications for clinical practice / Deborah Burgard -- Neuroscience : contributions to the understanding and treatment of eating disorders / Francine Lapides -- Are media an important medium for clinicians? Mass media, eating disorders, and the bolder model of treatment, prevention, and advocacy / Michael P. Levine -- -- II. Bridging the Gap : Diagnosis and Treatment -- -- The assessment process : refining the clinical evaluation of patients with eating disorders / Drew A. Anderson, Jackson M. Lavender, and Kyle P. De Young -- Medical assessment of eating disorders / Edward P. Tyson -- Psychiatric medication : management, myths, and mistakes / Martha M. Peaslee Levine and Richard L. Levine -- Nutritional impact on the recovery process / Jillian K. Croll -- Science or art? Integrating symptom management into psychodynamic treatment of eating disorders / Nancy L. Cloak and Pauline S. Powers -- New pathways : applying acceptance and commitment therapy to the treatment of eating disorders / Kathy Kater -- Outpatient treatment of anorexia nervosa following weight restoration : practical and conceptual issues / Richard A. Gordon -- Recipe for recovery : necessary ingredients for the client's and clinician's success / Beth Hartman McGilley and Jacqueline K. Szablewski -- -- III. Bridging the Gap : Special Populations -- -- Borderline personlity and eating disorders : a chaotic crossroads / Randy A. Sansone and Lori A. Sansone -- Managing the eating disorder patient with a comorbid substance use disorder / Amy Baker Dennis and Bethany L. Helfman -- Comorbid trauma and eating disorders : treatment considerations and recommendations for a vulnerable population / Diann M. Ackard and Timothy D. Brewster -- Healing self-inflicted violence in adolescents with eating disorders : a unified treatment approach / Kimberly Dennis and Jancey Wickstrom -- The weight-bearing years : eating disorders and body image despair in adult women / Margo Maine -- Men with eating disorders : the art and science of treatment engagement / Douglas W. Bunnell IV. Bridging the Gap : Family Issues -- -- Mutuality and motivation in the treatiment of eating disorders : connecting with patients and families for change / Mary Tantillo and Jennifer Sanftner -- When helping hurts : the role of the family and significant others in the treatment of eating disorders / Judith Brisman -- The most painful gaps : family perspectives on the treatment of eating disorders / Robbie Munn ... [et al.] -- -- V. Bridging the Gap : Mind, Body, and Spirit -- -- The role of spirituality in eating disorder treatment and recovery / Michael E. Berrett, Randy K. Hardman and P. Scott Richards -- The case for integrating mindfulness in the treatment of eating disorders / Kimberli McCallum -- The use of holistic methods to integrate the shattered self / Adrienne Ressler, Susan Kleinman and Elisa Mott -- Incorporating exercise into eating disorder treatment and recovery : cultivating a mindful approach / Rachel M. Calogero and Kelly N. Pedrotty-Stump -- Body talk : the use of metaphor and storytelling in body image treatment / Anita Johnston -- -- VI. Bridging the Gap : Future Direction -- -- The research/practice gap : challenges and opportunities for the eating disorder treatment professional / Judith D. Banker and Kelly L. Klump.
  • 2007 Springer
    Andrea Celli, Luigi Celli, Bernard F. Morrey [editors].
    1. Anatomy and Biomechanics of the Elbow / A. Celli -- 2. The Clinical Examination of the Elbow / A. Hinssche, D. Stanley -- 3. Imaging of the Elbow / V. Spina, L. Baldini -- 4. Elbow Surgical Approaches / A. Celli, L. Celli -- 5. The Treatment of Distal Humerus Fractures / S.W. O'Driscoll -- 6. The Fractures of the Olecranon / J.E. Adams, S.P. Steinmann -- 7. The Radial Head Fractures / M.W. Hartman, S.P. Steinmann -- 8. The Treatment of Coronoid Fractures and their Complications / A.G. Schneeberger -- 9. Lateral Collateral Ligament Injury / D. Stanley -- 10. The Complex Dislocations of the Elbow / G.J.W. King -- 11. The Fracture-Dislocation of the Forearm (Monteggia and Essex-Lopresti Lesions) / A. Celli, M.C. Marongiu, M. Fontana, L. Celli -- 12. The Instability after Radial Head Excision / S.L. Jensen -- 13. The Radial Head Prosthesis: Historical Perspective / C. Rovesta, C. Minervini, G. Bonanno, L. Celli -- 14. The Swanson Radial Head Prosthesis / B. Martinelli -- 15. Bipolar Radial Head Prosthesis / A. Celli -- 16. Evolve Modular Metallic Radial Head Arthroplasty / G.J.W. King -- 17. Radial Head Prosthetic Replacement with the Avanta Implant / B.F. Morrey -- 18. Radial Head Replacement with a Pyrocarbon Head Prothesis: Preliminary Results of a Multicentric Prospective Study / Y. Allieu, M. Winter, J.P. Pequignot, P. De Mourgues -- 19. Elbow Stiffness / A. Celli, L. Celli -- 20. The Arthroscopic Treatment of the Stiff Elbow / S.W. O'Driscoll -- 21. The Surgery of Neglected Distal Humerus Fractures in Children and Adults / L.P. Müller, M. Hansen, B.F. Morrey, K.J. Prommersberger, P.M. Rommens -- 22. Total Elbow Replacement for Rheumatoid Arthritis / B.F. Morrey -- 23. Total Elbow Arthroplasty in Acute Fracture / A. Celli -- 24. Latitude Convertible Total Elbow Prosthesis / G.J.W. King, K. Yamaguchi, S.W. O'Driscoll -- 25. Total Elbow Arthroplasty for Post-traumatic Arthrosis / A.G. Schneeberger, B.F. Morrey -- 26. Revision of Failed Elbow Arthroplasty / B.F. Morrey -- 27. Elbow Nerve Tunnel Syndromes / A. Celli, C. Rovesta, M.C. Marongiu -- 28. Traumatic Isolated Lesions of Musculocutaneous Nerve / C. Rovesta, M.C. Marongiu, G. Bonanno, A. Celli, L. Celli -- 29. The Traumatic Nerve-Vascular Lesions / R. Adani, G. Leo, L. Tarallo -- 30. The Utility of Continuous Axial Brachial Plexus Catheters after Surgery / F. Gazzotti, L.V. Indrizzi, G. Magni, E. Bertellini, A. Tassi -- 31. Elbow Brace in Physical Therapy / R. Rotini, A. Marinelli.
  • 2006
    editor-in-chief, Elaine Wyllie ; associate editors, Ajay Gupta, Deepak K. Lachhwani.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer
    Heinz Mehlhorn, Zhongdao Wu, Bin Ye, editors.
    This book intensively examines the efficacy of plant-derived products that have been used for over a thousand years by practitioners of so-called Traditional Chinese Medicine in the light of recent chemotherapeuticals. The chapters were wri