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  • V. 1 -- Sect. 1: Thoracic surgery -- Pt. A: Evaluation and care -- Pt. B: Endoscopy -- Pt. C: Trauma -- Pt. D: Trachea -- Pt. E: Benign lung disease -- Pt. F: Lung cancer -- Pt. G: Other lung malignancy -- Pt. H: Chest wall -- Pt. I: Pleura -- Pt. J: Diaphragm -- Pt. K: Esophagus-Benign disease -- Pt. L: Esophagus-cancer -- Pt. M: Mediastinum -- Pt. N: The future -- Sect. 2: Adult cardiac surgery -- Pt. A: Basic science -- Pt. B: Diagnostic procedures -- Pt. C: Medical- and catheter-based treatment of cardiovascular disease -- Pt. D: Perioperative and intraoperative care of the cardiac surgical patient -- V. 2 -- Pt. E: Surgical management of aortic disease -- Pt. F: Surgical management of valvular heart disease -- Pt. G: Management of cardiac arrhythmias -- Pt. H: Surgical management of coronary artery disease and its complications -- Pt. I: Surgical management of heart failure -- Sect. 3: Congenital heart surgery.
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    Expert consensus / G. Rees, J. Bartram and D. Kay -- Bivalves: global production and trade trends / S. Pawiro -- Adverse health outcomes / T.K. Graczyk, K. Suresh and D. Lees -- Driving forces and risk management / G. Rees, I. Karunasagar and J. Santo Domingo -- Identification of primary sources of faecal pollution / J.W. Santo Domingo and T.A. Edge -- Components of microbiological monitoring programmes / R. Lee and L. Murray -- Real-time monitoring technologies for indicator bacteria and pathogens in shellfish and shellfish harvesting waters / A.P. Dufour and G.N. Stelma Jr. -- Sanitary profiling of shellfish harvesting areas / R. Lee ... [et al.] -- Depuration and relaying / D. Lees, A. Younger and B. Doré -- Overview of legislative principles and measures / L. Murray and R. Lee -- é Scotland / L. Murray -- Official control monitoring programmes for live bivalve molluscs - legislative and regulatory approaches: Canada / G. Sauvé -- Official control monitoring programmes for live bivalve molluscs - legislative and regulatory approaches: New Zealand / P. Busby -- Current management practices / G. Rees ... [et al.] -- Experience from recreational waters / D. Kay ... [et al.] -- Microbial modelling in coastal environments and early warning systems: use full tools to limit shellfish micorbial contamination / M. Gourmelon ... [et al.] -- Framework for change / D. Kay and G. Rees.
  • "This book is a warning. It aims to warn policy-makers, industry, academia civil society organisations, the media and the public about the threats and vulnerabilities facing our privacy, identity, trust, security and inclusion in the rapidly approaching world of ambient intelligence (AmI)." "In the near future, every manufactured product - our clothes, money, appliances, the paint on our walls, the carpets on our floors, our cars, everything - will be embedded with intelligence, networks of tiny sensors and actuators, which some have termed "smart dust". The AmI world is not far off. We already have surveillance systems, biometrics, personal communicators, machine learning and more. AmI will provide personalised services - and know more about us - on a scale dwarfing anything hitherto available." "In the AmI vision, ubiquitous computing, communications and interfaces converge and adapt to the user. AmI promises greater user-friendliness in an environment capable of recognising and responding to the presence of different individuals in a seamless, unobtrusive and often invisible way. While most stakeholders paint the promise of AmI in sunny colours, there is a dark side to AmI as well." "The book identifies threats and vulnerabilities and illustrates them by means of four "dark scenarios". The authors set out a structured methodology for analysing AmI scenarios and propose safeguards to counter the foreseen threats and vulnerabilities. They make recommendations to policy-makers and other stakeholders about what they can do to maximise the benefits from ambient intelligence and minimise the negative consequences."--Jacket.
  • Cosmetic products and their current regulatory framework -- Challenges related to cosmetic safety assessment in the EU -- Critical analysis of the safety assessment of cosmetic ingredients performed at the European level -- Safety assessment of cosmetic ingredients present in technical information files of finished products -- The cosmetic technical information file in practice -- The use of alternative methods in the safety assessment of cosmetic ingredients.
  • 1. Introduction -- I. Biocompatibility -- II. Scope of Devices and the Medical Device Market -- III. History -- IV. Nonspecific Regulatory Considerations -- 2. Regulatory Aspects and Strategy in Medical Device and Biomaterials Safety Evaluation -- I. Regulatory Basis -- II. Toxicity Testing: Medical Devices -- 3. Road Map to Test Selections -- I. Key Concepts -- II. Conditions of Use -- III. Materials, Components, and Products -- IV. Prior Knowledge -- V. Types and Uses of Tests -- 4. What to Test: Sampling and Sample Preparation -- I. Sampling -- II. Randomization -- III. Sample Preparation -- IV. Reference Materials -- V. Conclusion -- 5. Cytotoxicity Testing -- I. Background -- II. Cytotoxicity Assays -- III. Conclusion -- 6. Blood Compatibility -- I. Introduction -- II. Standard Tests -- III. Conclusion -- 7. Irritation and Pyrogenicity -- I. Dermal Irritation -- II. Ocular Irritation Testing -- III. Other Nonparenteral Route Irritation Tests -- IV. Parenteral Irritation/Tolerance -- V. Parenteral Routes -- VI. Intracutaneous Irritation -- VII. Problems in Testing (and Their Resolutions) -- 8. Immunotoxicology -- I. Overview of the Immune System -- II. Evaluation of the Immune System -- III. Local Lymph Node Assay -- IV. Approaches -- V. Problems and Future Directions -- 9. Implantation Biology and Studies -- I. USP Implantation Test -- II. British Pharmacopoeia -- III. ISO 10993 Implantation Test -- IV. Test Method for Implantation in Subcutaneous Tissue -- V. Test Method for Implantation in Muscle -- VI. Test Method for Implantation in Bone -- VII. Control Materials -- VIII. Long-Term Implant Studies -- IX. Considerations -- 10. Genotoxicity -- I. DNA Structure -- II. Cytogenetics -- III. In Vitro Cytogenetic Assays -- IV. In Vivo Cytogenetic Assays -- V. Sister Chromatid Exchange Assays -- 11. Subchronic and Chronic Toxicity and Reproductive and -- Developmental Toxicity -- I. Objectives -- II. Regulatory Considerations -- III. Parameters to Measure -- IV. Histopathology -- V. Study Interpretation and Reporting -- VI. Reproductive and Developmental Toxicity -- 12. Carcinogenicity -- I. Animal Model -- II. Dose Selection -- III. Interpretation of Results -- 13. Sterility, Sterilization, and Heavy Metals -- I. Sterility -- II. Heavy Metals -- 14. Combination Devices -- I. Combination Products -- II. Device Programs that CDER and CBRH Will Administer -- 15. Clinical Studies for Medical Devices -- I. Design Considerations -- II. Epidemiology -- III. Conclusion -- 16. Special Studies -- I. Cardiovascular Devices and Prostheses -- II. Tampons -- III. Contact Lenses and Their Solutions -- IV. Specific Tests -- V. Twenty-One-Day Eye Irritation Study in Rabbits -- VI. Systemic Injection Test -- VII. Production of Toxic Shock Syndrome Toxin-l (TSST-1) -- VIII. In Vitro Evaluation of the Effects of Potential Tampon -- Materials on pH and Growth of Vaginal Microflora -- IX. Inflammatory Responses to Biomaterials -- 17. Case Histories and Problem Resolution -- I. Phthalate and Other Residuals Leaching from Devices -- II. Dalkon Shield -- III. Talc on Gloves and Condoms -- IV. Toxic Shock Syndrome -- V. Latex Allergy -- VI. Silicones in Devices -- VII. Problem Solving -- VIII. Risk Assessments -- IX. Conclusion -- Appendix A. Selected Regulatory and Toxicological Acronyms -- and Abbreviations -- Appendix B. Contract Testing Laboratories -- Appendix C. Notable Regulatory Internet Addresses -- Appendix D. Non-U.S. Medical Device Regulators.
  • In medical practice, unfamiliarity with procedures increases the likelihood of occupational exposures. Learning to perform a procedure properly early on reinforces safe habits, improves overall surgical safety, and reduces occupational exposures. Safety in Office-Based Dermatologic Surgery is relevant to any healthcare professional who participates in office-based procedures, such as injections, biopsies, excisions, and laser surgery. The authors bring over 15 years? combined experience in training residents and medical students, enabling them to identify common unsafe practices in office-based surgery. Chapters are divided into individual procedures for easy referencing by students, trainees, as well as seasoned practitioners. Figures illustrate how seemingly innocuous actions and procedures can result in dangerous exposures to healthcare workers. Hazardous scenarios are subsequently followed with one or a series of safer solutions, with the accident and solution concisely explained and clearly illustrated.
  • "This book covers the regulatory required evaluation and study of the potentially adverse pharmacological effects of new drugs, from the general regulatory requirements to the specific studies that must be done and how they are performed and interpreted. Based on more than 30 years of direct experience, the author describes tricks and practical insights for making studies work and understanding why they don't. The second edition includes current regulations (US FDA and international especially Europe and Japan) and updated test methods, interpretation, and science"--Provided by publisher.
  • Introduction to Enhanced Recovery Programs: A Paradigm Shift in Perioperative Care -- Section I: The Science of Enhanced Recovery: Building Blocks for your Program -- Peroperative Education -- Medical Optimization and Prehabilitation -- Preoperative Fasting and Carbohydrate Treatment -- Bowel Preparation: Always, Sometimes, Never? -- The Role of the Anesthesiologist in Reducing Surgical Stress and Improving Recovery -- Prevention of Hypothermia -- Prevention of Postoperative Nausea and Vomiting -- Thromboprophylaxis -- Surgical Site Infection Prevention -- Fluid Management -- Postoperative Ileus: Prevention and Treatment -- Choosing Analgesia to Facilitate Recovery -- Early Nutrition and Early Mobilization: Why They Are Important and How to Make it Happen -- Management of Tubes, Drains, and Catheters -- Hospital Recovery and Full Recovery -- Section II: Creation and Implementation of an Enhanced Recovery Program -- Overcoming Barriers to the Implementation of an Enhanced Recovery After Surgery Program -- Introducing Enhanced Recovery Programs into Practice: Lessons Learned from The ERAS® Society Implementation Program -- Enhanced Recovery Programs: Making the Business Case -- Audit: Why and How -- Why Add an ERP to a Laparoscopic Case: The Colorectal Experience -- Section III: Examples of Enhanced Recovery Programs -- Enhanced Recovery Programs for Colorectal Surgery: University Hospitals Case Medical Center -- Enhanced Recovery Programs for Colorectal Surgery: The Guilford: (UK) Experience -- Setting up an Enhanced Recovery Program Pathway for Bariatric Surgery: Current Evidence into Practice -- Enhanced Recovery Pathways in Hepato-pancreato-biliary Surgery -- Enhanced Recovery Programs for Upper Gastrointestinal Surgery: How I Do It -- Department-Wide Implementation of an Enhanced Recovery Pathway -- The ERAS® Society -- SAGES SMART Enhanced Recovery Program.
  • The SAGES Manual of Hernia Repair will serve as a state-of-the-art resource for hernia surgeons and residents alike who are interested in the rapidly evolving area of abdominal wall hernia repair. This manual captures and summarizes the current trends in the field, as well as describing the new ideas, programs, and strategies regarding hernia repair. Through a unique section called Current Debates in Inguinal Hernia Repair, this volume also provides readers an overview of the current opinions on many of the ongoing debates of this time period. Furthermore, the manual is lavishly illustrated, containing an array of instructional charts and photographs, and is authored by a panel of experts in hernia repair.Comprehensive and easily accessible, The SAGES Manual of Hernia Repair is a portable reference that will be of great value to all practicing surgeons and residents working in the field of abdominal wall hernia repair.
  • Part 1. Fundamentals of Surgical Energy -- Evolutions and Revolutions in Surgical Energy / Steven D. Schwaitzberg -- Fundamentals of Electrosurgery -- Part I: Principles of Radiofrequency Energy for Surgery / Malcolm G. Munro -- Fundamentals of Electrosurgery -- Part II: Thermal Injury Mechanisms and Prevention / L. Michael Brunt -- The Art and Science of Monopolar Electrosurgery / C. Randle Voyles -- Bipolar Electrosurgical Devices / Chan W. Park and Dana D. Portenier -- Electrosurgical Energy in Gastrointestinal Endoscopy / Brian J. Dunkin and Calvin D. Lyons -- Ultrasonic Energy Systems / James G. Bittner, J. Esteban Varela and Daniel Herron -- Cavitron Ultrasonic Surgical Aspirator / James S. Choi -- Principles and Safety of Radiofrequency and Cryo Ablation / Pascal R. Fuchshuber -- Principles and Safety of Microwave Ablation / Ryan Z. Swan and David A. Iannitti -- Surgical Energy Systems in Pediatric Surgery / Gretchen Purcell Jackson -- Integration of Energy Systems with Other Medical Devices / Stephanie B. Jones and Marc A. Rozner -- How to Report Adverse Events Related to the Use of Energy Devices in the Operating Room / Charlotte L. Guglielmi -- Part 2. Enrichment Chapters -- Hands-On Station: Fundamentals and Safety of Radiofrequency Electrosurgery / Malcolm G. Munro -- Hands-on Station: Art and Science of Monopolar Electrosurgery - Case Studies of Metal-to-Metal Arcing and Single Port Cannula Surgery / C. Randle Voyles -- Hands-on Station: Thermal Spread with Bipolar Electrosurgery / Dean Mikami -- Hands-on Station: Ultrasonic Energy Devices / Dana D. Portenier -- Hands-on Station: Cavitron Ultrasonic Surgical Aspirator (CUSA) and Argon Beam Device / James S. Choi -- Hands-on Station: Radiofrequency Ablation / Pascal R. Fuchshuber -- Hands-on Station: Microwave Devices / Ryan Z. Swan and David A. Iannitti -- Hands-on Station: Effects of Monopolar and Bipolar Electrosurgery on Cardiovascular Implantable / Electrical (Pacemakers or Implanted Cardioverter Defibrillator) Devices / Marc A. Rozner and Stephanie B. Jones -- Hands-on Station: Radiofrequency Electrosurgery in Gastrointestinal Endoscopy / Jeffrey W. Hazey.
  • SAGES manual.. 3rd ed. v.1-2=, 2012
    Fulltext v. 2 Springer
    V. 1. Basic laparoscopy and endoscopy / Nathaniel J. Soper and Carol E.H. Scott-Conner, editors -- v. 2. Advanced laparoscopy and endoscopy / Ninh T. Nguyen and Carol E.H. Scott-Conner, editors.
  • Anatomy, biogenesis, and regeneration of salivary glands / Holmberg, K.V.; Hoffman, M.P. -- Salivary secretion : mechanism and neural regulation / Proctor, G.B.; Carpenter, G.H. -- Salivary pellicles / Lindh, L.; Aroonsang, W.; Sotres, J.; Arnebrant, T. -- Antimicrobial defense systems in saliva / Nieuw Amerongen, A.V.; van't Hof, W.; Ligtenberg, A.J.M.; Veerman, E.C.I. -- Saliva and wound healing / Veerman, E.C.I.; Ligtenberg, A.J.M.; Brand, H.S. -- Role of saliva in oral food perception / Neyraud, E. -- Lubrication / Yakubov, G.E. -- Saliva diagnostics : utilizing oral fluids to determine health status / Schafer, C.A.; Schafer, J.J. ; Yakob, M.; Lima, P.; Camargo, P.; Wong, D.T.W. -- The use of saliva markers in psychobiology : mechanisms and methods / Bosch, J.A. -- Xerostomia / Delli, K.; Spijkervet, F.K.L.; Kroese, F.G.M.; Bootsma, H.; Vissink, A. -- Drooling / Silvestre-Donat, F.J.; Silvestre-Rangil, J. -- Salivary gland diseases : infections, sialolithiasis, and mucoceles / Delli, K.; Spijkervet, F.K.L.; Vissink, A.
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  • Introduction to salivary glands : structure, function, and embryonic development / Miletich, I. -- Salivary gland adaptations : modification of the glands for novel uses / Tucker, A.S. -- Genetic regulation of salivary gland development in drosophila melanogaster / Pirraglia, C. ; Myat, M.M. -- Extracellular matrix and growth factors in salivary gland development / Sequeira, S.J. ; Larsen, M. ; DeVine, T. -- Lumen formation in salivary gland development / Wells, K.L. ; Patel, N. -- Epithelial stem/progenitor cells in the embryonic mouse submandibular gland / Lombaert, I.M.A. ; Hoffman, M.P. -- Salivary gland regeneration / Carpenter, G.H. ; Cotroneo, E. -- Salivary gland disease / Thomas, B.L. ; Brown, J.E. ; McGurk, M.
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    1. Introduction -- 2. Differences in the nature of chicken meat production and the implications for salmonella and campylobacter -- 3. Review of available scientific information on control of salmonella and campylobacter : occurrence and challenges, and state of the science -- 4. Examples of possible interventions for hazard reduction -- 5. Evaluation of likey outcomes of specific interventions -- 6. Development of a Web-based risk-management tool -- 7. Summarized considerations of CCFH request -- 8. References -- Appendix.
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  • Salmonella methods and protocols 2007
    Springer Protocols
    Quantitative, multiplexed detection of salmonella and other pathogens by Luminex xMAP suspension array / Sherry A. Dunbar and James W. Jacobson -- Detection of salmonella by bacteriophage felix 01 / Jonathan C. Kuhn -- Physical mapping of salmonella genomes / Shu-Lin Liu -- Cloth-based hybridization array system for the identification of antibiotic resistance genes in salmonella / Burton W. Blais and Martine Gauthier -- Genome-based identification and molecular analysee of pathogenicity islands and genomic islands in Salmonella enterica / Michael Hensel -- Determination of the gene content of salmonella genomes by microarray analysis / Steffen Porwollik and Michael McClelland -- In vivo excision, cloning, and broad-host-range transfer of large bacterial DNA segments using VEX-capture / James W. Wilson and Cheryl A. Nickerson -- Amplified fragment length polymorphism analysis of Salmonella enterica / Ruiting Lan and Peter R. Reeves -- Salmonella phages and prophages : genomics and practical aspects / Andrew M. Kropinski ... [et al.] -- Salmonella typhimurium phage typing for pathogens / Wolfgang Rabsch -- Salmonella phages examined in the electron microscope / Hans-W. Ackermann -- Applications of cell imaging in salmonella research / Charlotte A. Perrett and Mark A. Jepson -- Analysis of kinesin accumulation on salmonella-containing vacuoles / Audrey Dumont ... [et al.] -- Magnesium, manganese, and divalent cation transport assays in intact cells / Michael E. Maguire -- Methods in cell-to-cell signaling in salmonella / Brian M. M. Ahmer ... [et al.] -- Development of salmonella strains as cancer therapy agents and testing in tumor cell lines / Abraham Eisenstark ... [et al.] -- Further resources for molecular protocols in salmonella research / Abraham Eisenstark and Kelly K. Edwards.
  • This second edition of Samii's Essentials in Neurosurgery contains revised and updated versions of chapters from the first edition plus contributions on new topics written by leading neurosurgeons who were trained by Professor Madjid Samii in Hannover, Germany. Almost all fields of neurosurgery are covered. The authors follow the traditional principles of Samii's philosophy in the diagnosis and management of various neurosurgical pathologies, while presenting their own personal experiences. The extensively illustrated texts document clearly how cutting-edge technology in neurosurgery is being applied in new approaches and techniques. This book will greatly assist neurosurgeons, ENT surgeons, neuroradiologists, neurologists, and neurophysiotherapists in their everyday practice.
  • Considerations prior to sample size calculation -- Comparing means -- Large sample tests for proportions -- Exact tests for proportions -- Tests for goodness-of-fit and contingency tables -- Comparing time-to-event data -- Group sequential methods -- Comparing variabilities -- Bioequivalence testing -- Dose response studies -- Microarray studies -- Bayesian sample size calculation -- Nonparametrics -- Sample size calculation in other areas.
  • v. 1. Recognition : innate and adaptive immunity -- Effector mechanisms : innate and adaptive -- Primary immunodeficiencies -- Proliferation disorders of immunologic cells -- v. 2. Systemic diseases -- Organ-specific diseases -- Allergic diseases -- Evasion, activation and ineffective immunity -- Transplantation -- Therapeutic immunology.
  • Coma, head trauma, and spinal cord injury / Galen V. Henderson -- Epilepsy / Edward B. Bromfield and Barbara A. Dworetzky -- Dizziness / Robert W. Baloh -- Back and neck pain / Allan H. Ropper -- Sleep disorders / Milena Pavlova -- Neurooncology / Patrick Y. Wen and Santosh Kesari -- Multiple sclerosis and other demyelinating diseases / Maria K. Houtchens and David M. Dawson -- Motor neuropathies and peripheral neuropathies / Anthony A. Amato -- Neuromuscular junction disorders and myopathies / Anthony A. Amato -- Chronic pain / Robert D. Helme -- Headache and facial pain / Elizabeth Loder and Paul Rizzoli -- Stroke and cerebrovascular disorders / Steven K. Feske -- Movement disorders / Lewis Sudarsky -- Behavioral neurology and dementia / Kirk R. Daffner and David A. Wolk -- Neuroophthalmology / Marc J. Dinken and Don C. Bienfang -- Toxic and metabolic disorders / Martin A. Samuels -- Infections of the central nervous system / Tracey A. Cho.
  • Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care.Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. Diagnose AIDS manifestations confidently by comparing them to full-color clinical images. Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness. Efficiently review essential data through numerous at-a-glance tables. Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings. Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine. The very latest in HIV/AIDS management from global experts with a concise approach and a clinical/practical focus.
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    Introduction -- The interview -- The history -- The case record -- General appearance -- The vital signs -- Integument -- Lymph nodes -- The head -- The eye -- The ear -- The nose -- The oropharynx -- The neck -- The breast -- The chest -- The heart -- Arteries -- Veins -- The abdomen -- Male genitalia -- Female genitalia -- The rectum -- The extremities -- The musculoskeletal system -- The neurologic examination -- Clinical reasoning -- Some bedside laboratory tricks.
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  • The sarcomere and sarcomerogenesis / Elisabeth Ehler and Mathias Gautel -- Skeletal muscle alpha-actin diseases / Kathryn N. North and Nigel G. Laing -- Nebulin : a giant chameleon / Katarina Pelin and Carina Wallgren-Pettersson -- Skeletal muscle disease due to mutations in tropomyosin, troponin, and cofilin / Nigel F. Clarke -- Investigations into the pathobiology of thin-filament myopathies / Biljana Ilkovski -- Mouse models for thin filament disease / Mai-Anh T. Nguyen and Edna C. Hardeman -- Thick filament diseases / Anders Oldfors and Phillipa J. Lamont -- Acute quadriplegic myopathy : an acquired "myosinopathy" / Lars Larsson -- Third filament diseases / Bjarne Udd -- The Z-disk diseases / Duygu Selcen and Olli Carpén -- Intermediate filament diseases : desminopathy / Lev G. Goldfarb ... [et al.] -- Muscular integrity : a matter of interlinking distinct structures via plectin / Patryk Konieczny and Gerhard Wiche -- The sarcomere and the nucleus : functional links to hypertrophy, atrophy, and sarcopenia / Mathias Gautel -- Other model organisms for sarcomeric muscle diseases / John Sparrow, Simon M. Hughes, and Laurent Segalat -- Therapeutic approaches for the sarcomeric protein diseases / Kristen J. Nowak.
  • Overview of Sarcopenia -- Muscle wasting in cancer and ageing: cachexia versus sarcopenia -- Age-related remodeling of neuromuscular junctions -- Aging related changes motor unit structure and function -- Excitation-contraction coupling regulation in aging skeletal muscle -- Alterations in mitochondria and their impact in aging skeletal muscle -- Skeletal muscle collagen: age, injury and disease -- Nuclear apoptosis and sarcopenia -- Age-related changes in the molecular regulation of skeletal muscle mass -- Genetic variation and skeletal muscle traits: implications for sarcopenia -- Proteomic and biochemical profiling of aged skeletal muscle -- Exercise and nutritional interventions to combat age-related muscle loss -- Reactive oxygen species generation and skeletal muscle wasting, implications for sarcopenia -- Exercise as a countermeasure for sarcopenia -- Role of contraction-induced injury in age-related muscle wasting and weakness -- Role of IGF-1 in age-related loss of skeletal muscle mass and function -- Role of myostatin in skeletal muscle growth and development: implications for sarcopenia -- Role of beta-adrenergic signalling in skeletal muscle wasting: implications for sarcopenia -- Index.
  • A pancoronavirus RT-PCR assay for detection of all known coronaviruses / Leen Vijgen ... [et al.] -- Detection of group 1 coronaviruses in bats using universal coronavirus reverse transcription polymerase chain reactions / Leo L.M. Poon and J.S. Malik Peiris -- Detection and sequence characterization of the 3'-end of coronavirus genomes harboring the highly conserved RNA motif s2m / Christine Monceyron Janassen -- RT-PCR detection of avian coronaviruses of galliform birds (chicken, turkey, pheasant) and in a parrot / Francesca Anne Culver, Paul Britton, and Dave Cavanagh -- Detection of group 2a coronaviruses with emphasis on bovine and wild ruminant strains / Mustafa Hasoksuz, Anastasia Vlasova, and Linda J. Saif -- Detection of SARS coronavirus in humans and animals by conventional and quantitative (real time) reverse transcription polymerase chain reactions / J.S. Malik Peiris and Leo L.M. Poon -- Detection of new viruses by VIDISCA / Krzysztof Pyrc ... [et al.] -- Titration of human coronaviruses, HCoV-229E and HCoV-OC43, by an indirect immunoperoxidase assay / Francine Lambert ... [et al.] -- The preparation of chicken tracheal organ cultures for virus isolation, propagation, and titration / Brenda V. Jones and Ruth M. Hennion -- Isolation and propagation of coronaviruses in embryonated eggs / James S. Guy -- Large-scale preparation of UV-inactivated SARS coronavirus virions for vaccine antigen / Yasuko Tsunetsugu-Yokota -- Purification and electron cryomicroscopy of coronavirus particles / Benjamin W. Neuman ... [et al.] -- Production of coronavirus nonstructural proteins in soluble form for crystallization / Yvonne Piotrowski ... [et al.] -- Generating antibodies to the gene 3 proteins of infectious bronchitis virus / Amanda R. Pendleton and Carolyn E. Machamer -- Establishment and characterization of monoclonal antibodies against SARS coronavirus / Kazuo Ohnishi -- Production of monospecific rabbit antisera recognizing nidovirus proteins / Jessika C. Zevenhoven-Dobbe ... [et al.] -- Manipulation of the coronavirus genome using targeted RNA recombination with interspecies chimeric coronaviruses / Cornelis A.M. de Haan ... [et al.] -- Generation of recombinant coronaviruses using vaccinia virus as the cloning vector and stable cell lines containing coronaviral replicon RNAs / Klara Kristin Eriksson, Divine Makia, and Volker Thiel -- Transient dominant selection for the modification and generation of recombinant infectious bronchitis coronaviruses / Maria Armesto ... [et al.] -- Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes / Fernando Almazán, Carmen Galán, and Luis Enjuanes -- Systematic assembly and genetic manipulation of the mouse hepatitis virus A59 genome / Eric F. Donaldson, Amy C.Sims, and Ralph S. Baric -- Identification of sugar residues involved in the binding of TGEV to porcine brush border membranes / Christel Schwegmann-Wessels and Georg Herrler -- Pseudotyped vesicular stomatitis virus for analysis of virus entry mediated by SARS coronavirus spike proteins / Shuetsu Fukushi, Rie Watanabe, and Fumihiro Taguchi.
  • SAS for dummies 2007
    books24x7, SUNet ID login required.
    2007 ProQuest Safari
  • SAS functions by example. 2nd ed. 2010
    books24x7, SUNet ID login required.
    2010 ProQuest Safari
    Character functions -- Perl regular expressions -- Sort functions -- Date and time functions -- Array functions -- Truncation functions -- Descriptive statistics functions -- Mathematical and numeric functions -- Random number functions -- Special functions -- State and ZIP code functions -- Trigonometric functions -- Macro functions -- SAS file I/O functions -- Variable information functions -- Bitwise logical functions.
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  • "Includes comprehensive hazard information on the substances encountered in the workplace. The objective of the work is to promote safety by providing the most up-to-date hazard information available"--Provided by publisher. "Since its inception in the early 1950's, this book has become the "bible" for those who need to evaluate the hazard of substances used in commerce. The book contains extensive data on approximately 28,000 substances. It is designed to fill the information needs of professionals who must work with and evaluate the hazards of chemicals"--Provided by publisher.
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  • Laparoendoscopic Single-Site Surgery (LESS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES) are based on the premise that patients should benefit in terms of recovery time, physical discomfort, pain, and cosmesis if a surgical procedure can be performed without visible scarring. Scar-Less Surgery: NOTES, Transumbilical, and Others is a multi-disciplinary effort which weaves together the surgical aspects of these novel techniques. It is the first comprehensive reference on the subject providing state-of-the-art technical information to both general and urologic surgeons while also highlighting future developments and research needs.
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  • "The 9th Edition brings you fully up to date in the field, with coverage of new diagnostic tools, new information on drug-induced liver injury and cytopathology, and many new high-quality illustrations. Throughout the text, you'll find technical tips, diagnostic clues, and pearls that reflect the extensive experience and insight of the late Dr. Peter Scheuer and internationally renowned author Dr. Jay Lefkowitch, making this new edition your standard bench-side guide to today's liver biopsy diagnosis"--Publisher's description.
  • History taking and physical examination for the patient with liver disease -- Laboratory tests -- Liver biopsy and laparoscopy -- Imaging -- Interventional radiology procedures for diagnosis and treatment of hepatobiliary disease -- Endoscopic retrograde cholangiopancreatography -- Physioanatomic considerations -- Bilirubin metabolism and jaundice -- Hepatic histopathology -- Mehanisms of liver injury -- The liver in systemic disease -- Hematologic disorders and the liver -- Nutrition and the liver -- Hepatic fibrosis -- Portal hypertension and nonsurgical management -- Surgical management of portal hypertension -- Renal complications and hepatorenal syndrome -- Pulmonary manifestations of liver disease -- Ascites and spontaneous bacterial peritonitis -- Hepatic encephalopathy -- fulminant hepatic failure -- Gallstone disease: pathogenesis and treatment -- Primary sclerosing cholangitis -- Primary biliary cirrhosis -- Postoperative jaundice -- The hepatitis viruses -- Hepatitis A -- Hepatitis E -- Hepatitis B and D -- Hepatitis C -- Autoimmune hepatitis -- Alcoholic liver disease -- Drug-induced liver disease -- Mechanisms of drug-induced liver injury -- Wilson disease -- Hemochromatosis and iron storage disorders -- a₁-Antitrypsin deficiency -- Porphyrias -- Nonalcoholic fatty liver disease -- Vasucular diseases of the liver -- The liver in circulatory failure -- Benign solid tumors -- Nodular and cystic lesions -- Hepatocellular carcinoma -- Surgical options for the treatment of hepatocellular carcinoma -- Liver disease in infancy and childhood -- The liver in pregnancy -- Liver abscesses -- Parasitic diseases -- Bacterial and systemic infections -- Hepatobiliary manifestations of human immunodeficiency virus -- Granulomas of the liver -- Selection and timing of liver transplantation -- Immunosuppression: the global picture -- The first 6 months following liver transplantation -- The long-term care of transplanted patient -- The surgical options of liver transplantation -- Recurrent disease following liver transplantation -- The role of retransplantation -- Hepatobiliary complications of hematopoietic cell transplantation.
  • Introduction -- The schistosomes -- The snail -- Prevalence in final host -- Immunological studies -- Disease manifestation and pathology -- Parasitological diagnosis -- Immunodiagnosis -- Chemotherapy -- Control -- Laboratory models developed -- Technologies developed.
  • Schistosomiasis 2005
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    The cardinal symptoms of schizophrenia -- The clinical pictures of schizophrenia -- The natural history of schizophrenia -- The diagnosis of schizophrenia -- Aetiological factors in schizophrenia -- The neurochemistry of schizophrenia -- The neurodevelopmental theory of schizophrenia -- The psychology and neuropsychology of schizophrenia -- The cognitive neuropsychology of schizophrenia -- Neuroleptic drug treatment -- The management of schizophrenia -- Paraphrenia and paranoia -- Schizoaffective and other atypical psychoses -- Schizophrenia and organic brain disease -- Childhood schizophrenia, autism and Asperger's syndrome -- Schizophrenia and personality.
  • "Schizophrenia: Recent Advances in Diagnosis and Treatment is a major addition to the literature, offering practical, comprehensive coverage of diagnosis and treatment options, genetic issues, neuroimaging, long-term management of schizophrenia, and future directions and predictions of how clinical care of schizophrenia will change. The book is divided into five sections. Section 1 summarizes the present state of knowledge about the diagnosis and treatment of schizophrenia. This includes recent changes in the DSM 5 categorization of schizophrenia and its implications for treatment. Section 2 considers recent discoveries into its pathoetiology, including the status of biological markers, genetics and neuroimaging as they relate to diagnosis and potential novel therapeutic approaches. Section 3 explores the optimization of present therapeutic approaches; novel treatments; and management of the substantial risks associated with both the illness and its present therapies. Section 4 discusses progress in the long-term management of schizophrenia, focusing on biological and psychotherapeutic strategies to improve functioning and facilitate recovery. Section 5 considers future directions and predictions of how diagnosis and treatment of schizophrenia will change. An invaluable addition to the field, Schizophrenia: Recent Advances in Diagnosis and Treatment is a definitive resource that will be of great interest to all clinicians caring for patients with schizophrenia."--Publisher's website.
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  • 2012 ClinicalKey
    V. 1: -- Ensuring Patient Safety in Surgery-First Do No Harm -- Surgical Navigation with Intraoperative Imaging: Special Operating Room Concepts -- Functional Tractography, Diffusion Tensor Imaging, Intraoperative Integration of Modalities, and Neuronavigation -- Intraoperative Neurophysiology: A Tool to Prevent and/or Document Intraoperative Injury to the Nervous System -- Gamma Knife Surgery for Cerebral Vascular Malformations and Tumors -- Cortical and Subcortical Brain Mapping -- Chemotherapy for Brain Tumors -- Current Surgical Management of High-Grade Gliomas -- Surgical Management of Low-Grade Gliomas -- Management of Recurrent Gliomas -- Tumors in Eloquent Areas of Brain -- Management of Primary Central Nervous System Lymphomas -- Surgical Management of Brain Stem Tumors in Adults -- Cerebellar Tumors in Adults -- Surgical Management of Cerebral Metastases -- Multimodal Assessment of Pituitary and Parasellar Lesions -- Medical Management of Hormone-Secreting Pituitary Tumors -- Growth Hormone-Secreting Tumors -- Prolactinomas -- Cushing's Disease -- Endocrinologically Silent Pituitary Tumors -- Endoscopic Endonasal Pituitary and Skull Base Surgery -- Transcranial Surgery for Pituitary Macroadenomas -- Craniopharyngiomas -- Endoscopic Endonasal Approach for Craniopharyngiomas -- Arachnoid, Suprasellar, and Rathke's Cleft Cysts -- Surgical Approaches to Lateral and Third Ventricular Tumors -- Transcallosal Surgery of Lesions Affecting the Third Ventricle: Basic Principles -- Endoscopic Approach to Intraventricular Brain Tumors -- Management of Pineal Region Tumors -- Management of Tumors of the Fourth Ventricle -- Surgical Management of Parasagittal and Convexity Meningiomas -- Surgical Approach to Falcine Meningiomas -- Surgical Management of Midline Anterior Skull Base Meningiomas -- Supraorbital Approach Variants for Intracranial Tumors -- Surgical Management of Sphenoid Wing Meningiomas -- Spheno-Orbital Meningioma -- Tumors Involving the Cavernous Sinus -- Surgery for Trigeminal Neurinomas -- Surgical Management of Petroclival Meningiomas -- Surgical Management of Lesions of the Clivus -- Surgical Management of Posterior Fossa Meningiomas -- Surgical Management of Tumors of the Foramen Magnum -- Surgical Management of Tumors of the Jugular Foramen -- Suboccipital Retrosigmoid Surgical Approach for Vestibular Schwannoma (Acoustic Neuroma) -- Translabyrinthine Approach to Vestibular Schwannomas -- Transtemporal Approaches to Posterior Cranial Fossa -- Surgical Management of Neurofibromatosis Types 1 and 2 -- Hearing Prosthetics: Surgical Techniques -- Multimodal Treatment of Orbital Tumors -- Surgical Approaches to the Orbit -- Anterior Midline Approaches to the Skull Base -- Orbitozygomatic Infratemporal Approach to Parasellar Meningiomas -- Methods for Cerebrospinal Fluid Diversion in Pediatric Hydrocephalus: From Shunt to Scope -- Posterior Fossa Tumors in the Pediatric Population: Multidisciplinary Management -- Supratentorial Tumors in the Pediatric Population: Multidisciplinary Management -- Mapping, Disconnection, and Resective Surgery in Pediatric Epilepsy -- Surgical Decision-Making and Treatment Options for Chiari Malformations in Children -- Fetal Surgery for Open Neural Tube Defects -- Surgical Management of Spinal Dysraphism -- Revascularization Techniques in Pediatric Cerebrovascular Disorders -- Management of Pediatric Severe Traumatic Brain Injury -- Contemporary Dorsal Rhizotomy Surgery for the Treatment of Spasticity in Childhood -- Instrumentation and Stabilization of the Pediatric Spine: Technical Nuances and Age-Specific Considerations -- Methods of Cranial Vault Reconstruction for Craniosynostosis -- Surgical Management of Extracranial Carotid Artery Disease -- Management of Dissections of the Carotid and Vertebral Arteries -- Management of Unruptured Intracranial Aneurysms -- Surgical Management of Intracerebral Hemorrhage -- Surgical Management of Cerebellar Stroke-Hemorrhage and Infarction -- Surgical Treatment of Moyamoya Disease in Adults -- Surgical Treatment of Paraclinoid Aneurysms -- Surgical Management of Posterior Communicating, Anterior Choroidal, Carotid Bifurcation Aneurysms -- Surgical Management of Anterior Communicating and Anterior Cerebral Artery Aneurysms -- Surgical Management of Aneurysms of the Middle Cerebral Artery -- Surgical Management of Terminal Basilar and Posterior Cerebral Artery Aneurysms -- Surgical Management of Midbasilar and Lower Basilar Aneurysms -- Surgical Management of Aneurysms of the Vertebral and Posterior Inferior Cerebellar Artery Complex -- Far Lateral Approach and Transcondylar and Supracondylar Extensions for Aneurysms of the Vertebrobasilar Junction -- Surgical Management of Cranial Dural Arteriovenous Fistulas -- Surgical Management of Cavernous Malformations of the Nervous System -- Surgical Management of Infratentorial Arteriovenous Malformations -- Surgical Management of Cerebral Arteriovenous Malformations -- Endovascular Management of Intracranial Aneurysms -- Endovascular Treatment of Stroke -- Endovascular Treatment of Cerebral Arteriovenous Malformations -- Endovascular Treatment of Intracranial Occlusive Disease -- Endovascular Treatment of Extracranial Occlusive Disease -- Embolization of Tumors: Brain, Head, Neck, and Spine -- Endovascular Management of Dural Arteriovenous Fistulas -- Endovascular Management of Spinal Vascular Malformations -- Endovascular Treatment of Head and Neck Bleeding -- Imaging Evaluation and Endovascular Treatment of Vasospasm -- Surgical Management of Hydrocephalus in the Adult -- Adult Pseudotumor Cerebri Syndrome -- Endoscopic Third Ventriculostomy -- Management of Shunt Infections -- Interstitial and LINAC-Radiosurgery for Brain Metastases -- Stereotactic Radiosurgery for Trigeminal Neuralgia -- CyberKnife Radiosurgery for Spinal Neoplasms -- Stereotactic Radiosurgery for Pituitary Adenomas -- Radiation Therapy and Radiosurgery in the Management of Craniopharyngiomas -- Vestibular Schwannomas: The Role of Stereotactic Radiosurgery -- Stereotactic Radiosurgery Meningiomas -- Role of Gamma Knife Radiosurgery in the Management of Arteriovenous Malformations -- Radiation Therapy of Epilepsy -- Gamma Surgery for Functional Disorders -- V. 2: -- Presurgical Evaluation for Epilepsy Including Intracranial Electrodes -- Temporal Lobe Operations in Intractable Epilepsy -- Surgical Management of Extratemporal Lobe Epilepsy -- Multilobar Resection and Hemispherectomy in Epilepsy Surgery -- Corpus Callosotomy: Indications and Techniques -- Treatment of Intractable Epilepsy by Electrical Stimulation of the Vagus Nerve -- Deep Brain Stimulation in Movement Disorders: Parkinson's Disease, Essential Tremor, and Dystonia -- Cervical Dystonia and Spasmodic Torticollis: Indications and Techniques -- Novel Targets in Deep Brain Stimulation for Movement Disorders -- Molecular Therapies for Movement Disorders -- Cingulotomy for Intractable Psychiatric Illness -- Deep Brain Stimulation for Intractable Psychiatric Illness -- Brain-Computer Interfacing Prospects and Technical Aspects -- Thoracoscopic Sympathectomy for Hyperhidrosis -- Surgery for Intractable Spasticity -- Retrogasserian Glycerol Rhizolysis in Trigeminal Neuralgia -- Percutaneous Stereotactic Rhizotomy in the Treatment of Intractable Facial Pain -- Neurovascular Decompression in Cranial Nerves V, VII, IX, and X -- Deep Brain Stimulation for Pain -- Mesencephalic Tractotomy and Anterolateral Cordotomy for Intractable Pain -- Spinal Cord Stimulation for Chronic Pain -- Spinal Cord Stimulation and Intraspinal Infusions for Pain -- Dorsal Root Entry Zone Lesions -- Motor Cortex Stimulation for Intractable Facial Pain -- Perioperative Management of Severe Traumatic Brain Injury in Adults -- Surgical Management of Severe Closed Head Injury in Adults -- Management of Penetrating and Blast Injuries of the Nervous System -- Decompressive Craniectomy for Traumatic Brain Injury -- Management of Skull Base Trauma -- Surgical Management of Chronic Subdural Hematoma in Adults -- Management of Cerebrospinal Fluid Leaks -- Principles of Scalp Surgery and Surgical Management of Major Defects of Scalp -- Surgical Management of Major Skull Defects and Potential Complications -- Management of Traumatic Intracranial Aneurysms -- Management of Penetrating Brain Injury -- Management of Suppurative Intracranial Infections -- Management of Infections After Craniotomy -- Spinal Infections: Vertebral Osteomyelitis and Spinal Epidural Abscess -- Neurosurgical Management of HIV-Related Focal Brain Lesions -- Management of Neurocysticercosis -- Management of Tuberculous Infections of the Nervous System -- Fungal Infections of the Central Nervous System -- Management of Intracranial Aneurysms Caused by Infection -- Treatment Evolution in Management of Cervical Disc Disease -- Anterior Cervical Foraminotomy (Jho Procedure): Microscopic or Endoscopic -- Minimally Invasive Posterior Cervical Foraminotomy and Microdiscectomy -- Disc Replacement Technologies in the Cervical and Lumbar Spine -- Anterior Approaches for Multilevel Cervical Spondylosis -- Management of Cervical Spondylotic Myelopathy -- Cervical Laminoplasty: Indications and Techniques -- Circumferential Cervical Spinal Fusion -- Surgical Techniques in the Management of Thoracic Disc Herniations -- Video-Assisted Thoracoscopic Discectomy: Indications and Techniques -- Lumbar Microdiscectomy: Indications and Techniques -- Lumbar Microdiscectomy: Indications and Techniques -- Minimally Invasive Lumbar Microdiscectomy: Indications and Techniques -- Management of Far Lateral Lumbar Disc Herniations -- Lumbar Spinal Arthroplasty: Clinical Experiences of Motion Preservation -- Management of Degenerative Lumbar Stenosis and Spondylolisthesis -- Posterior Lumbar Fusion by Open Technique: Indications and Techniques -- Percutaneous Placement of Lumbar Pedicle Screws: Indications and Techniques -- Dynamic Stabilization of the Lumbar Spine: Indications and Techniques -- Posterior Lumbar Interbody Fusion -- Transforaminal Lumbar Interbody Fusion: Indications and Techniques -- Anterior Lumbar Interbody Fusion: Indications and Techniques -- Lateral Lumbar Interbody Fusion: Indications and Techniques -- Vertebroplasty and Kyphoplasty: Indications and Techniques -- Management of Injuries of the Cervical Spine and Spinal Cord -- Transoral Approaches to the Cervical Spine -- Atlantoaxial Instability and Stabilization -- Stabilization of the Subaxial Cervical Spine (C3-C7) -- Thoracolumbar Anterolateral and Posterior Stabilization -- Management of Sacral Fractures -- Management of Penetrating Injuries to the Spine -- Craniovertebral Abnormalities and Their Neurosurgical Management -- Management of Chiari Malformations and Syringomyelia -- Management of Occult Spinal Dysraphism in Adults -- Neurologic Problems of the Spine in Achondroplasia -- Management of Degenerative Scoliosis -- Surgical Management of Intramedullary Spinal Cord Tumors in Adults -- Intradural Extramedullary Tumors -- Management of Spinal Cord Tumors and Arteriovenous Malformations -- Management of Cauda Equina Tumors -- Management of Primary Malignant Tumors of the Osseous Spine -- Surgical Approaches to the Cervicothoracic Junction -- Surgery for Metastatic Spine Disease -- Surgical Resection of Sacral Tumors -- Surgical Management of Cerebrospinal Fluid Leakage after Spinal Surgery -- Peripheral Nerve Injury -- Imaging for Peripheral Nerve Disorders -- Management of Adult Brachial Plexus Injuries -- Nerve Transfers: Indications and Techniques -- Management of Median Nerve Compression -- Management of Ulnar Nerve Compression -- Management of Entrapment Neuropathies -- Management of Nerve Sheath Tumors Involving the Spine -- Peripheral Nerve Tumors of the Extremities -- Management of Cranial Nerve Injuries -- Management of Thoracic Outlet Syndrome -- Nerve-Grafting Procedures for Birth-Related Peripheral Nerve Injuries.
  • School-related violence and prevention : editorial introduction / Thomas W. Miller -- Theory, assessment, and forms of school violence: School-related violence : definition, scope, and prevention goals / Thomas W. Miller and Robert F. Kraus. The neurobiology of violence and victimization / William P. French. Threat assessment in school violence / Connie Callahan. Social information processing and aggression in understanding school violence : an application of Crick and Dodge's model / Amy Nigoff. The roles of morality development and personal power in mass school shootings / Ken Kyle and Stephen Thompson. Multiple contextual levels of risk for peer victimization : a review with implications for prevention and intervention efforts / Noel A. Card, Jenny Isaacs, and Ernest V. E. Hodges. Assessment of childhood sexual abuse : clinical measures, evaluation, and treatment / Mark V. Sapp. Impact of trauma in school violence on the victim and the perpetrator : a mental health perspective / Lane J. Veltkamp and Amy Lawson. Boundary violations : harassment, exploitation, and abuse / Thomas W. Miller and Lane J. Veltkamp. Cliques and cults as a contributor to violence in the school environment / Thomas W. Miller, Thomas F. Holcomb, and Robert F. Kraus -- Teatment and prevention of violence in the schools: Violence in our schools / Matt Thompson, Bobbie Burcham, and Kathy McLaughlin. The role of teachers in school violence and bullying prevention / Jina S. Yoon and Elizabeth Barton. Developmental issues in the prevention of aggression and violence in school / Paul Boxer, Andrew Terranova, Sarah Savoy, and Sara E. Goldstein. Bullies and victims at school : perspectives and strategies for primary prevention / Christian Berger, Ramin Karimpour, and Philip C. Rodkin. The psychiatrist's role after a school shooting: the emergency room and beyond / Elissa P. Benedek and Praveen Kambam. Current perspectives on linking school bullying research to effective prevention strategies / Dorothy L. Espelage and Susan M. Swearer. School shootings in middle school, high school, and college : clinical management and school interventions for high-risk students / Thomas W. Miller, William Weitzel, and Janet Lane. Character education as a prevention strategy for school-related violence / Thomas W. Miller, Robert F. Kraus, and Lane J. Veltkamp. The bully free program : a profile for prevention in the school setting / Allan Beane, Thomas W. Miller, and Rick Spurling. A series of culturally relevant models to prevent school-age youth violence : a 4-year (2001-2005) family and community violence prevention study / Laxley W. Rodney, Rameshwar P. Srivastava, and Dana L. Johnson. Prevention of school violence : directions, summary, and conclusions / J. Robert McLaughlin and Thomas W. Miller.
  • "The recent advances in many aspects of kidney diseases have mandated a new edition of Schrier's Diseases of the Kidney. As in previous editions, a group of international experts was assembled to present this information in a comprehensive, authoritative, concise, and readily accessible fashion. The chapters have been extensively revised and updated"--Provided by publisher.
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  • Introduction -- pt. I. Background to drug discovery and development -- pt. II. The drug development pipeline: discovery to testing in humans -- pt. III. The drug development pipeline: clinical trials to marketing authorization -- pt. IV. The global pharmaceuticals business -- pt. V. Professional interactions with drug discovery industry.
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  • The care of critically ill and injured children needs to be safe, evidence-based, equitable, efficient, timely, and family-centered. "Science and Practice of Pediatric Critical Care Medicine" discusses these changes in the specialty in greater scope and detail, offering the reader fresh insight into not only where we came from, but also where we are going as a specialty. Thus, this book is designed for all involved in the management of the pediatric critically ill patient, from physicians, residents and fellows in critical care, pulmonology, cardiology and pediatricians to specialist.
  • Medicine, media, and the dramaturgy of biomedical research: historical perspectives / John H. Warner -- Delgado's brave bulls: the marketing of a seductive idea and a lesson for contemporary biomedical research / Peter J. Snyder -- Adrenal transplantation for Parkinson's disease / Dennis D. Spencer -- The use of SSRIs in the treatment of childhood depression: a scientific dialectic / Peter Fonagy -- Media coverage of stem cell research / David H. Smith, Aaron Klink, Julius Landwirth -- Medicine's obsession with disclosure of financial conflicts: fixing the wrong problem / Jerome P. Kassirer -- In support of industry-sponsored clinical research / Declan P. Doogan -- Prevailing truth: the interface between religion and science / Wesley Carr -- Science meets fundamentalist religion / Pat Shipman -- Uneasy alliance: the intersection of government science, politics and policymaking / Ruth J. Katz -- On the relationship between scientists and journalists: reflections by an ethicist / Robert J. Levine -- Don't shoot the messenger / Laura Spinney -- Future trends in medical research publishing / Harry W. McConnell, Ashley Pardy -- Conclusion: the ethics of scientific disclosure / Peter J. Snyder, Linda C. Mayes.
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    "Keeping his focus on America, Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed that the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and skeptically"-- Provided by publisher.
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  • Introduction : the science of well-being : reviews and theoretical articles by Ed Diener / Ed Diener -- Subjective well-being / Ed Diener -- In pursuit of happiness : empirical answers to philosophical questions / Pelin Kesebir and Ed Diener -- Personality and subjective well-being / Richard E. Lucas and Ed Diener -- Beyond the hedonic treadmill : revising the adaptation theory of well-being / Ed DIener, RIchard E. Lucas and Christie Napa Scollon -- Will money increase subjective well-being? : a literature review and guide to needed research / Ed Diener and Robert Biswas-Diener -- The well-being of nations : linking together trust, cooperation, and democracy / William Tov and Ed Diener -- The optimum level of well-being : can people be too happy? / Shigehiro Oishi, Ed Diener, and Richard E. Lucas -- Beyond money : toward an economy of well-being / Ed Diener and Martin E.P. Seligman -- Conclusion : the well-being science needed now / Ed Diener.
  • The book does not focus primarily on grammar, but includes sections on important facets, such as 'voices' and tenses. It also addresses problems associated with writing other texts (reports, reviews, emails, social/professional networking communications etc.). Composed (with inputs from numerous senior scientists) by authors who have written, revised or edited more than 4,000 papers, A Scientific Approach to Scientific Writing will be essential reading for non-native English-speaking students and researchers of all disciplines, and a valuable resource for those with English as a first language."--pub. desc.
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  • "In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. The volume on Arthritis covers, rheumatoid arthritis, cytokines, leukocyte immunoglobulin-like receptors, alleles, cardiovascular risk, disease outcomes, treatment protocols, and drugs for arthritis. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.
  • "In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. This volume on Asthma covers, inter alia, asthma care in primary care centers, rhinosinusitis and asthma, asthma and psychological distress, inhalation techniques for different inhalers, emergency treatment for acute asthma, therapy for elderly patients, treatment for pediatric asthma, nursing care at home and so on. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.
  • HIV/AIDS : an overview / Francis Agyemang-Yeboah and Bernard C. Nkum -- Can teens teach other teens HIV prevention? : implications for AIDS and pregnancy / Ganga Mahat and Maryann Scoloveno -- Knowledge of antenatal attendees about HIV/AIDS in pregnancy / Anietie Effiong Moses, Emem Abasi Bassey, and Godwin Etim Asuquo -- Midwives and occupational exposures to HIV / Maria Ganczak -- Pregnancy and delivery in HIV positive women : antenatal care and outcome / Karoline Aebi-Popp, Christoph Rudin, and Luigia Elzi -- Management of HIV/AIDS stigma : nursing perspectives / Susan W. Gaskins -- Prenatal assistance to pregnant women with HIV/AIDS / Prescilla Chow ... [et al.] -- Antenatal screening and HIV-pregnancy : strategies for treatment / Ali A. Al-Jabri ... [et al.] -- Low lymphocyte count in HIV-pregnancy and strategies for treatment / Alashle Abimiku and Evaezi Okpokoro -- Antiretroviral regimens recommended for prevention of mother-to-child transmission of HIV / Christiana Smith and Adriana Weinberg -- Pregnancy-related adverse effects of antiretroviral therapy / Elie Azria, Sophie Matheron, and Dominique Luton.
  • Epidemiology of angina / John F. Beltrame -- Chest pain : cardiac and non-cardiac causes / Geraldine Lee -- Coronary plaque rupture in patients with acute coronary syndrome / Toshio Imanishi -- The use and application of angina questionnaires / Norul Badriah Hassan and Muhammad Termizi Hassan -- American College of Cardiology/American Heart Association guidelines for ST-elevation myocardial infarction : overview of guidelines for care before, during, and after STEMI / Rohit S. Loomba and Rohit R. Arora -- Non-invasive coronary angiography with cardiac CT in patients with angina pectoris / Christof Burgstahler, Harald Brodoefel, and Stephen Schroeder -- Drugs used in angina : an overview / Mario Marzilli and Alda Huqi -- Current clinical application of direct thrombin inhibitors in angina pectoris / Bernardo Cortese and Marco Centola -- Anti-anginal drugs in focus : trimetazidine / Mario Marzilli and Alda Huqi -- Enhanced external counterpulsation therapy in coronary artery disease management / Ozlem Soran and Debra L. Braverman.
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    Describes the path that led to the discovery of the Arias-Stella reaction. Uses fictional names for the local protagonists, e.g., Pedro Asari Saltel for Javier Arias-Stella.
  • About the editors/authors -- Contributors -- Preface -- Acknowledgments -- 1. Organization and content of book -- 2. What is forensic document examination -- 3. A forensic document examiners training -- 4. Care and handling of documents -- 5. Work notes -- 6. The Daubert era -- 7. Conclusions and guidelines for handwriting comparison -- 8. Identification of handwriting -- 9. Identification of signatures -- 10. Identification of hand printing and numerals -- 11. Disguise in hand printing and numerals -- 12. Preparation and collection of signatures and handwriting standards -- 13. Pens and pencils -- 14. Typography -- 15. Typewriters -- 16. The examination of computer-generated documents -- 17. Photocopiers -- 18. Facsimile machines -- 19. Manipulated photocopies, faxes, and computer-printed documents -- 20. Rubber stamps -- 21. Checkwriters -- 22. Staples -- 23. Conventional printing processes -- 24. Paper examinations -- 25. Carbonless paper -- 26. Accidental markings and indented writing on a document -- 27. Alterations in documents -- 28. Multi-faceted approach -- 29. The role of indentation analysis, offsetting, and transfer -- 30. Dating by materials: identification, comparison, and examination of changes -- 31. Cameras, scanners, and image enhancement -- 32. Conclusions and guidelines -- 33. Considerations in preparing for court -- 34. Demonstrative charts -- 35. Pretrial conference -- 36. Preparation for a Daubert hearing -- 37. The untrained document expert witness -- 38. The document examiners testimony in court -- Glossary -- Index.
  • Scientific neurological basis for assessment -- Introductory scientific history to neuropsychological assessment -- Nature of science -- Theoretical foundation of neurological assessment -- Neuropsychological basis of assessment -- Brain-function analysis -- Formal analytic methodology -- Neuropsychological battery patterns -- Justification of formal procedures -- Fundamental psychometric status of neuropsychological batteries -- Justification of neuropsychological batteries -- Accuracy of formal neuropsychological methods -- Application to forensics -- Admissibility of neuropsychological expert testimony under the Daubert and Frye evidentiary standards -- Usefulness of a validated neuropsychological test battery is scientifically supporting and communicating forensic evaluation results -- Formal neuropsychological methods -- In defense of the Halstead-Reitan Battery: a critique of Lezak's review -- In defense of the Halstead-Reitan Battery: revisited -- Norming subjects for the Halstead-Reitan Battery -- Major Halstead-Reitan Battern norm sets.
  • Presents a new framework for preparing students with the scientific know-how optimal for studying medicine and becoming physicians.
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    v. 1, Analytical aspects.
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    v.1 - Renal disorders infections and calculi. v.2 - Urogenital tract, oncology and the urological armamentarium.
  • The semantic environment of science -- Before you begin -- Organizing and writing a rough draft -- Searching and reviewing scientific literature -- The proposal -- The graduate thesis -- Publishing in scientific journals -- Style and accuracy in the final draft -- Reviewing and revising -- Titles and abstracts -- Presenting data -- Ethical and legal issues -- Scientific presentations -- Communication without words -- Visual aids to communication -- The oral presentation -- Poster presentations -- Group communications -- Communicating with other audiences -- To the international student.
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    v. 1. Studies in cellular physiology -- v. 2. Radical dietary treatment of vasular and metabolic disorders.
  • 1. Introduction -- 2. Scientific training and personal development -- 3. The scientific method -- 4. Attributes required by research scientists -- 5. The impact of managerialism -- 6. Leadership in science -- 7. Insights from notable scientists -- 8. Future challenges for scientific research.
  • Sclera. 2nd ed. 2012
    Structural Considerations of the Sclera -- Immunologic Considerations of the Sclera -- Diagnostic Approach of Episcleritis and Scleritis -- Clinical Considerations of Episcleritis and Scleritis -- Pathology in Scleritis -- Noninfectious Scleritis -- Infectious Scleritis -- Noninflammatory Diseases of the Sclera -- Treatment of Episcleritis and Scleritis.
  • pt. 1. Introduction -- pt. 2. Epidemiology, genetics and classification -- pt. 3. Scleroderma in children -- pt. 4. Other fibrosing skin conditions -- pt. 5. Pathogenetic basis -- pt. 6. Cardiovascular manifestations and management -- pt. 7. Pulmonary manifestations and management -- pt. 8. Gastrointestinal manifestations and management -- pt. 9. Skin, musculoskeletal and other complications -- pt. 10. Disease-modifying strategies -- pt. 11. Outcome assessment.
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    I. Prefácio, por António Coutinho -- II. Notas para a História da Esclerose Múltipla, por Paulo Pacheco da Fontoura -- III. A Sclerose em Placas Disseminadas, por Vicente Ferreira de Moura -- IV. Notas Finais e Agradecimentos.
  • 2011 ClinicalKey
  • Volume 1: Cell biology -- Wound healing -- Immunology -- Microbiology -- Haematology -- Endocrinology -- Pharmacotherapeutics -- Perioperative management -- Safe and effective practice -- Interpreation and management of data -- Recent advances in technology -- Paediatric otorhinolaryngology -- Volume 2: The Nose and paranasal sinuses -- The neck -- The upper digestive tract -- The upper airway -- Head and neck tumours -- Volume 3: Plastic surgery of the head and neck -- The ear, hearing and balance -- Skull base.
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    1.Introduction: Scottish medicine and literary culture, 1726-1832 / Megan J. Coyer and David E. Shuttleton -- 2. 'Nothing is so soon forgot as pain': reading agony in Adam Smith's The theory of moral sentiments / Craig Franson --3. The origins of a modern medical ethics in enlightenment Scotland: Cheyne, Gregory and Cullen as practitioners of sensibility / Wayne Wild -- 4. The demise of the preformed embryo: Edinburgh, Leiden, and the physician-poet Mark Akenside's contribution to re-establishing epigenetic embryology / Robin Dix -- 5. Benjamin Rush, Edinburgh medicine and the rise of physician autobiography / Catherine Jones -- 6. The construction of Robert Fergusson's illness and death / Rhona Brown -- 7. 'Groaning under the miseries of a diseased nervous system': Robert Burns and melancholy / Allan Beveridge -- 8. Phrenological controversy and the medical imagination: 'A modern pythagorean' in Blackwood's Edinburgh Magazine / Megan J. Coyer -- 9. Blood and the revenant in Walter Scott's The Fair Maid of Perth / Katherine Inglis -- 10. Magic, mind control, and the body electric: "Materia Medica" in Sir Walter Scott's library at Abbotsford / Lindsay Levy -- 11. An Account of ... William Cullen: John Thomson and the making of a medical biography / David E. Shuttleton -- 12. Transatlantic irritability: Brunonian sociology, America and mass culture in the nineteenth century / Gavin Budge -- Index.
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  • Current epidemiological evidence suggests that at least one third of people with diabetes suffer from clinically relevant depressive disorders which often go unrecognized and untreated. Research also shows that people with depressive disorders have an increased risk of developing Type 2 diabetes. Furthermore, the prognosis is poorer for either disease when they are co-morbid than when they occur separately. Co-morbid depression and diabetes has a huge impact on quality of life and diabetes management, and is an important public health problem. While there are many screening instruments available to identify individuals who may have depression, selecting the most appropriate tool for use in a busy diabetes clinic or primary care setting may not be straightforward. Screening for Depression and Other Psychological Problems in Diabetes: A Practical Guide provides an up-to-date overview of available instruments for screening for depression in diabetes. The book reviews the most commonly used screening tools and considers their utility in a range of settings and countries. Guidance on the practical use of each tool is also provided. Other psychological problems found to be common in people with diabetes as well as diabetes-specific emotional difficulties are also considered. This book will appeal to a range of health care practitioners caring for people with diabetes, including diabetologists, general practitioners, practice nurses and diabetes specialist nurses. The issues considered here are applicable to all diabetes populations across the world and thus this book will appeal to a broad international readership as well as to researchers in the field of diabetes and mental health.
  • Scrotal pathology 2012
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  • Introduction -- The Evolution of Eye Surgery -- The Advent of Ambulatory Eye Surgery -- Anatomical Considerations -- Infection Control -- How the Patient Gets from the Front Door of the ASC to Your OR Suite -- Decorum in the OR -- Setting Up in the OR -- Contemplating Cataract Surgery -- Cataract Surgery -- Complications Encountered, Instruments at the Ready: Here Is a List of "What Ifs" and "What to Do's" -- The Surgical Tray for Cataract Surgery -- Surgeon-Specific Instruments -- Ocular Biometry -- Self-Assessment Test Cataract Surgery -- Surgical Checklist -- Corneal Surgery -- Corneal Transplantation: Penetrating Keratoplasty -- Corneal Transplantation: Keratoprosthesis -- Corneal Transplantation: Endothelial Keratoplasty -- Pterygium Surgery -- Band Keratopathy Removal -- Complications Encountered, Instruments at the Ready: Here Is a List of "What Ifs" and "What to Do's" -- The Surgical Tray for Penetrating Keratoplasty -- The Surgical Tray for Endothelial Keratoplasty -- Self-Assessment Test Corneal Surgery -- Resource Materials -- Medications List.
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    --sv. 2-5. [without special title].--sv. 6. Disertace Purkyňových žáků.--sv. 7. České práce fysiologické a morfologické.--sv. 8. Úvahy a pracé přírodovědné.--sv. 9. Věda, výchova, společnost, studie a úvahy.--sv. 10. Slavistické pracé.--sv. 11. Básně a překlady.--sv. 12. Fysiologie lidské mluvy a menší fysiologickě pracé.--sv. 13. Autobiografické stati. Bibliographia.
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  • Introduction / Emilio Mordini, Dimitrios Tzovaras, and Holly Ashton -- Epistemological foundation of biometrics / Giampaolo Ghilardi and Flavio Keller -- Biometric recognition : an overview / Anil K. Jain and Ajay Kumar -- Biometrics, privacy and agency / Annemarie Sprokkereef and Paul de Hert -- Gait and anthropomorphic profile biometrics : a step forward / Dimosthenis Ioannidis ... (et al.) -- Activity and event related biometrics / Anastasios Drosou and Dimitrios Tzovaras -- Electrophysiological biometrics : opportunities and risks / Alejandro Riera ... (et al.) -- Intelligent biometrics / Farzin Deravi -- Behavioral biometrics and human identity / Ben A.M. Schouten, Albert Ali Salah, and Rob van Kranenburg -- Behavioral biometrics : emerging trends and ethical risks / Günter Schumacher -- Facial recognition, facial expression and intention detection / Massimo Tistarelli, Susan E. Barrett, and Alice J. O'Toole -- The transparent body : medical information, physical privacy and respect for body integrity / Emilio Mordini and Holly Ashton -- Security in the danger zone : normative issues of next generation biometrics / Irma van der Ploeg -- The dark side of the moon : accountability, ethics and new biometrics / Juliet Lodge -- Conclusions / Emilio Mordini.
  • "Second harmonic generation serves as the basis for a microscope imaging contrast mechanism that visualizes cell and tissue structure and function. This book provides a complete overview of the principles underlying this technique and its current applications, including use in molecular sensing. Covering practical issues related to instrumentation, the text examines which kinds of external labels to use. It also gives detailed reviews of the use of second harmonic generation in biomedical research, from imaging of cancer and skin disorders to self-assembled gels, holographic SHG imaging, and tissue engineering applications"--Provided by publisher.
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    The commercialization of U.S. medicine -- The consequences of commercialized care -- The revolt of the payers -- "Consumer-driven" health care: the new new thing -- The reform we need -- Can we get there? do we want to? -- Lessons from Canada -- An open letter to my colleagues in the medical profession.
  • Victims -- Trauma -- Guilt -- Investigation -- Justice -- Forgiveness -- Support -- Resilience.
  • Open heart surgery has been in a continuous state of evolution since its earliest day. This book presents information on the management of secondary mitral valve regurgitation, one of most vexing problems to cardiologists, cardiac surgeons and patients. The treatment for primary mitral regurgitation is straightforward and has as its primary aim timely intervention to prevent left ventricular remodelling and left ventricular dysfunction. The management of secondary mitral regurgitation is more challenging as the mitral valve is not the primary cause of the disease. Furthermore, correcting mitral regurgitation without changing the left ventricular geometry is not guaranteed to be either beneficial or curative. Secondary Mitral Valve Regurgitation draws together contributions from a range of experienced cardiac surgeons, cardiologists, anesthetists and scientists to provide comprehensive and authoritative coverage on anatomy, hemodynamics, mechanism, echocardiographic assessment and treatment modalities. Many of the elusive details surrounding the best management of secondary mitral regurgitation are presented in a comprehensive manner so that this book will serve as an important primary source for readers wanting information on this important topic.
  • Disease in disguise -- Winged victories -- Food fright -- Superbugs -- The once and future pandemic -- Infection unmasked -- Bioterror.
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    Neuroscientist Penny Lewis explores the latest research into the nighttime brain to understand the real benefits of sleep, showing how, while our body rests, the brain practices tasks it learned during the day, replays traumatic events to mollify them, and forges connections between distant concepts.
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    1. Orthodoxy and American Practice -- 2. Old and New World Eclectics -- 3. Jeremiads and Apostates -- 4. Reform Literature -- 5. Reform Colleges -- 6. Reform Societies -- 7. Between the Abrahams -- Appendices -- A. Reform Medical Journals to 1909 -- B. Reform Medical Colleges to 1915 -- C. Reform Medical Societies to 1900.
  • CT of the abdomen / Kousei Ishigami -- MRI of the abdomen / Akihiro Nishie and Alan H. Stolpen -- CT of the male pelvis / Kousei Ishigami -- CT of the female pelvis / Kousei Ishigami -- MRI of the male pelvis / Akihiro Nishie and Alan H. Stolpen -- MRI of the female pelvis / Akihiro Nishie and Alan H. Stolpen. MR arthrography of the hip / Mark. J. Kransdorf -- MRI of the thigh / Mark J. Kransdorf -- MRI of the knee / Mark. J. Kransdorf -- MRI of the leg / Mark. J. Kransdorf -- MRI of the ankle / Mark. J. Kransdorf -- MRI of the foot / Mark. J. Kransdorf -- MRI of the thoracic spine / William J. Montgomery -- MRI of the lumbar spine / William J. Montgomery -- CT of the thorax / Brian F. Mullan -- MRI of the heart / Brian F. Mullan and Alan H. Stolpen -- MRI of the pectoral girdle and chest wall / Thomas P. Martin and Timothy Averion-Mahloch -- MRI of the shoulder / Thomas P. Martin and Timothy Averion-Mahloch -- MR arthrography of the shoulder / Thomas P. Martin and Timothy Averion-Mahloch -- MRI of the arm / Thomas P. Martin and Timothy Averion-Mahloch -- MRI of the elbow / Carol A. Boles -- MRI of the forearm / Carol A. Boles -- MRI of the wrist / Carol A. Boles -- MRI of the hand / Carol A. Boles -- MRI of the hip / Mark. J. Kransdorf --
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  • From the Publisher: Combining essential theory with "how-to" technical instruction, this concise guide is the leading reference for basic techniques in sedation and anxiety control in the dental office. The latest guidelines from the ADA and the American Society of Anesthesiologists keep you up-to-date with the latest medical standards. Content on patient management for pediatric, geriatric, physically compromised, and medically compromised patients helps you successfully treat any patient population. In-depth discussions of the pharmacology of commonly used sedative agents allow you to fully understand properties and characteristics of drugs used. Combines all aspects of sedation with essential theory and instruction. Boxes and tables highlight key information and make it easy to find important content. Chapter 40-Legal Considerations include the current liability standards for patient treatment to help you protect yourself and your patients. Chapter 41-The Controversial Development of Anesthesiology in Dentistry focuses on the growing controversies, legal and otherwise, from both without and within the profession. Updated patient management procedures provide the most current guidelines on everything from AHA CPR standards to the safest sedative procedures. Full-color art program shows anatomy and other important concepts in vibrant detail. Photos of the newest sedation and emergency equipment ensure you have the latest information on developments in the field.
  • This atlas demonstrates all components of the body through imaging, in much the same way that a geographical atlas demonstrates components of the world. Each body system and organ is imaged in every plane using all relevant modalities, allowing the reader to gain knowledge of density and signal intensity. Areas and methods not usually featured in imaging atlases are addressed, including the cranial nerve pathways, white matter tractography, and pediatric imaging. As the emphasis is very much on high-quality images with detailed labeling, there is no significant written component; however, 'pearl boxes' are scattered throughout the book to provide the reader with greater insight. This atlas will be an invaluable aid to students and clinicians with a radiological image in hand, as it will enable them to look up an exact replica and identify the anatomical components. The message to the reader is: Choose an organ, read the 'map,' and enjoy the journey.
  • Seeing 2000
    Formation and sampling of the retinal image / Larry N. Thibos -- The receptive fields of visual neurons / Robert Shapley -- Spatial vision / Wilson S. Geisler and Duane G. Albrecht -- Color vision / Karen K. De Valois and Russell L. De Valois -- Binocular vision / Clifton Schor -- Seeing motion / Andrew Derrington -- The neural representation of shape / Jack L. Gallant -- Visual attention / Jeremy M. Wolfe.
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    "... Use[s] extensive research and interviews with leading physicians to show how subconscious stereotyping influences doctor-patient interactions, diagnosis, and treatment"--From publisher description.
  • With a strong patient-centered approach to care and an author team comprised of nurses and physicians, Seidel's Guide to Physical Examination, 8th Edition, addresses teaching and learning health assessment in nursing, medical, and a wide variety of other health-care programs, at both undergraduate and graduate levels. This new edition offers an increased focus on evidence-based practice and improved readability, along with integrated lifespan content and numerous special features such as Clinical Pearls and Physical Variations, Functional Assessment, and Staying Well boxes. Evidence-Based Practice in Physical Examination boxes supply you with current data on the most effective techniques for delivering quality patient care.Clinical Pearls lend insights and clinical expertise to help you develop clinical judgment skills.Functional Assessment boxes present a more holistic approach to patient care that extends beyond the physical exam to patients' functional ability.Staying Well boxes focus you on patient wellness and health promotion. Risk Factor boxes provide opportunities for patient teaching or genetic testing for a variety of conditions.Differential diagnosis content offers you an understanding of how disease presentations vary and specific information for how to make diagnoses from similar abnormal findings.Abnormal Findings tables equip you with a quick, illustrated reference that allows for comparisons of various abnormalities along with key symptoms and underlying pathophysiology.Sample Documentation boxes clarify appropriate professional language for the process of recording patient assessment data.
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    Terminology and classifications -- Perspectives -- Mechanisms of neuronal excitation and synchronization -- Basic mechanisms of seizures and epilepsy -- Causes of human epilepsy -- Epileptic seizures -- Epilepsy syndromes -- Epileptogenesis -- Periictal phenomena -- Status epilepticus -- Chronic behavioral disturbances -- Diagnostic evaluation -- Differential diagnosis -- General principles of treatment -- Antiseizure drugs -- Nonpharmacological therapy of seizures -- Social management.
  • Chapter 1- Epidemiology of Seizures and Epilepsy in Cerebrovascular Disease -- Chapter 2: Seizures in Ischemic Stroke -- Chapter 3: Seizures in Intracerebral Hemorrhage -- Chapter 4: Seizures in Subarachnoid Hemorrhage -- Chapter 5: Seizures in subdural hematoma -- Chapter 6: Seizures in Cerebral Cavernous Malformations -- Chapter 7: Seizures in Arteriovenous Malformations -- Chapter 8: Seizures in Cerebral Venous Sinus Thrombosis -- Chapter 9: Pediatric Stroke and Seizures -- Chapter 10: Medical Management of Seizures in Cerebrovascular Disorders.
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    Presentation and pathophysiology of seizures in the critical care environment: an overview / Marek A. Mirski -- Stroke and critical care seizures / Panayiotis N. Varelas and Lotfi Hacein Bey -- Traumatic brain injury and seizures in the ICU / Andrew Beaumont and Grant Sinson -- Brain tumors and ICU seizures / Efstathios Papavassiliou and Panayiotis N. Varelas -- Global hypoxia-ischemia and critical care seizures / Matthew A. Koenig and Romergryko Geocadin -- Seizures in renal and hepatic failure and endocrine disease / Andrew Beaumont -- Seizures in organ transplant recipients / Greg A. Worrell and Eelco F. M. Wijdicks -- Extreme hypertension, eclampsia, and critical care seizures / Errol Gordon and Michel T. Torbey -- Infection or inflammation and ICU seizures / Wendy C. Ziai -- Electrolyte disturbance and critical care seizures / Jenice Robinson and Jose I. Suarez -- Alcohol-related seizures in the ICU / Zachary Webb -- Seizure-inducing drugs used for the critically ill / Rebecca E. Schuman and Panayiotis N. Varelas -- Critical care seizures related to illicit drugs and toxins / Andreas R. Luft -- Management of status epilepticus and critical care seizures / Panayiotis N. Varelas and Marianna V. Spanaki.
  • Presentation and pathophysiology of seizures in the critical care environment: an overview -- Diagnosing and monitoring seizures in the ICU: the role of continuous EEG for detection and management of seizures in critically ill patients -- Stroke and critical care seizures -- Traumatic brain injury and seizures in the ICU -- Brain tumors and ICU seizures -- Global hypoxia-ischemia and critical care seizures -- Seizures in fulminant hepatic failure, multiorgan failure, and endocrine crisis -- Seizures in organ transplant recipients -- Extreme hypertension, eclampsia and critical care seizures -- Infection or inflammation and ICU seizures -- Electrolyte disturbances and critical care seizures -- Alcohol-related seizures in the intensive care unit -- Drug-induced seizures in critically ill patients -- Critical care seizures related to illicit drugs and toxins -- Management of status epilepticus and critical care seizures.
  • 2013 ClinicalKey
    Section I. Epithelial and Nonepithelial Transport and Regulation -- Section II. Structural and Functional Organization of the Kidney -- Section III. Fluid and Electrolyte Regulation and Dysregulation -- Section IV. Pathophysiology of Renal Disease.
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    v. 1. On the early development of mind -- v. 2 The roots of crime.
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    The role of government in health care: a societal issue -- A simple continuous-flow blood transfusion instrument -- Carcinoma of the lung -- The development of vascular surgery -- Surgical treatment of aneurysm of abdominal aorta by resection and restoration of continuity with homograft -- Successful resection of aneurysm of thoracic aorta and replacement by graft -- Successful carotid endarterectomy for cerebrovascular insufficiency: nineteen-year follow-up -- Surgical considerations of dissecting aneurysm of the aorta -- Aneurysm of thoracoabdominal aorta involving the celiac, superior mesenteric, and renal arteries: report of four cases treated by resection and homograft replacement -- Patterns of atherosclerosis and their surgical significance -- Left ventricular bypass pump for cardiac assistance: clinical experience -- Human cardiac transplantation -- Aortocoronary bypass with saphenous vein graft: seven-year follow-up.
  • Selected References in Trauma and Orthopaedics provides a selection of references from the Trauma and Orthopedic literature, aimed at the surgeon preparing for the Intercollegiate Specialty Board examination, and similar end-of training examinations in other countries. It is the perfect guide for examiners and trainers who are preparing their trainees for the examination, as well as providing a literature basis for their own practice. Selected References in Trauma and Orthopaedics presents the classical papers underlying current practice as well as recent publications which have brought about innovation, clarified pathology or demonstrated outcomes. The references are presented with a brief summary which allows the reader to access a literature review, with the use of online resources, with the key references already identified.
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  • Selective sweep 2005
    Inferring evolutionary history through inter- and intraspecific DNA sequence comparison : the Drosophila janus and ocnus genes / John Parsch, Colin D. Meiklejohn and Daniel L. Hart -- Rapid evolution of sex-related genes : sexual conflict or sex-specific adaptations? / Alberto Civetta and Rama S. Singh -- Selective sweep in the evolution of a new sperm-specific gene in Drosophila / Rob J. Kulathinal ... [et al.] -- Detecting selective sweeps with haplotype tests : hitchhiking and haplotype tests / Frantz Depaulis, Sylvain Mousset and Michel Veuille -- A novel test statistic for the identification of local selective sweeps based on microsatellite gene diversity / Christian Schlutterer and Daniel Dieringer -- Detecting hitchhiking from patterns of DNA polymorphism / Justin C. Fay and Chung-I Wu -- Periodic selection and ecological diversity in bacteria / Frederick M. Cohan -- Distribution and abundance of polymorphism in the malaria genome / Stephen M. Rich -- Selective sweeps in structured populations-empirical evidence and theoretical studies / Thomas Wiehe, Karl Schmid and Wolfgang Stephan.
  • Pt. 1. Selenocysteine biosynthesis and incorporation into protein -- pt. 2. Selenoproteins and selenoproteins in health -- pt. 3. Selenium and selenoproteins in human health -- pt. 4. Mouse models for elucidating the role of selenium and selenoproteins in health.
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    v. 1, Body structure and function, nutrition and food management, basic pharmacology and drug therapy ; v. 2, Roles and responsibilities in nursing health ; v. 3, Medical and surgical nursing, mental illness ; v. 4, Mother and newborn, the well and sick child, communicable diseases.
  • What constitutes self-help in mental health and what can be done to improve it? -- The self-help movement in mental health : from passivity to interactivity -- Distance writing : helping without seeing participants -- Bibliotherapy -- Online support groups and therapy -- Manuals for practitioners -- Anxiety disorders -- Mood disorders -- Eating disorders : anorexia, bulimia, and obesity -- Addictive behaviors -- Personality disorders -- Severe psychopathology -- Medical conditions -- Who benefits by self-help and why?
  • Introduction / Juan M. Cabases and Rosalind Rabin -- Data and Methods / Bas Janssen, Agota Szende, and Juan Manuel Ramos-Goni -- Population Norms for the EQ-5D / Bas Janssen and Agota Szende -- Cross-Country Analysis of EQ-5D Data / Agota Szende and Bas Janssen -- Socio-demographic Indicators based on EQ-5D / Agota Szende and Bas Janssen -- Annex 1: EQ-5D population norms - National surveys -- Annex 2: EQ-5D population norms - Regional surveys -- References -- Index.
  • "Edward Laws and Jason Sheehan have edited the first comprehensive guide to the management of the large varieties of pathologies that arise in the sellar and parasellar area. Over the past two decades change in management practices have been underpinned by a better understanding of the nature of the pathology, improved imaging and a refinement of both surgical and radiation therapy techniques. The location of the sellar and parasellar region has challenged neurosurgeons (and radiotherapists) to develop innovative refined approaches to the region, often using the best of skull base, endoscopic and microsurgical techniques. These have been utilized within the context of an improved understanding of the pathology, with the imperative that the treatment (or therapy) must optimize control of the pathology, whilst minimizing morbidity"--Provided by publisher.
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  • The CRMP family of proteins and their role in Sema3A signaling / Eric F. Schmidt and Stephen M. Strittmatter -- GTPases in semaphorin signaling / Andreas W. Püchel -- Intracellular kinases in semaphorin signaling / Aminul Ahmed and Britta J. Eickholt -- Mical flavoprotein monooxygenases : structure, function and role in semaphorin signaling / Sharon M. Kolk and R. Jeroen Pasterkamp -- Signaling of secreted semaphorins in growth cone steering / Sangwoo Shim and Guo-li Ming -- Modulation of semaphorin signaling by IG superfamily cell adhesion molecules / Ahmad Bechara ... [et al.] -- Proteoglycans as modulators of axon guidance cue function / Joris de Wit and Joost Verhaagen -- Semaphorin signals in cell adhesion and cell migration : functional role and molecular mechanisms / Andrea Casazza, Pietro Fazzari, and Luca Tamagnone -- Semaphorin signaling during cardiac development / Toshihiko Toyofuku and Hitoshi Kikutani -- Semaphorin signaling in vascular and tumor biology / Gera Neufeld ... [et al.].
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    "The semblance hypothesis explains how associative memory can result from the multidimensional semblance of activity from a specific set of presynaptic terminals at different orders of neurons. The hypothesized basic units are then examined for their feasibility to explain various physiological and pathological conditions of the nervous system, ranging from physiological time-scales of memory retrieval to plausible explanation for long term potentiation (LTP)"--Back cover.
  • Introduction -- Biogenic Amines in the Skin -- Melatoninergic System in the Skin -- Cutaneous Cholinergic System -- Corticotropin Signaling System in the Skin -- Steroidogenesis in the Skin -- Equivalent of Hypothalamo-Pituitary-Adrenal Axis in the Skin -- Cutaneous Secosteroidal System -- Equivalent of Hypothalamic-Pituitary-Thyroid Axis -- Cutaneous Opioid System -- Cutaneous Endocannabinoid System -- Perspectives.
  • Ischemic tolerance in the brain : models and mechanisms / Michael Bell, Kelly Drew, Mark Smith and John Hallenbeck -- Regulation of gene expression by hypoxia in lung alveolar epithelial cells / Christine Clerici, Tokujiro Uchida, Carole Planès and Michael A. Matthay -- A profile of the metabolic responses to anoxia in marine invertebrates / Kevin Larade and Kenneth B. Storey -- The role of adenosine in tissue protection during ischemia-reperfusion / Gail W. Sullivan and Joel Linden -- NF-kB function in inflammation, cellular stress and disease / Neil R. Chapman, Sonia Rocha, Ian M. Adcock and Neil D. Perkins -- MAPping stress survival in yeasts : from the cell surface to the nucleus / Aaron Ngocky Nguyen and Kazuhiro Shiozaki -- Calcium signaling mediated by cyclic ADP-ribose and NAADP : roles in cellular response to stress / Hon Cheung Lee -- The cellular and molecular basis of the detection of pain / Jennifer K. Bonnington, David R. Robinson, Vittorio Vellani and Peter A. McNaughton -- Acquired freezing tolerance in higher plants : the sensing and molecular responses to low nonfreezing temperatures / Zhanguo Xin -- Sensing and responses to low temperature in cyanobacteria / Dmitry A. Los and Norio Murata -- Dehydrins / Jan Svensson, Abdelbagi M. Ismail, E. Tapio Palva and Timothy J. Close -- Dual role of membranes in heat stress : as thermosensors they modulate the expression of stress genes and, by interacting with stress proteins, re-organize their own lipid order and functionality / László Vígh and Bruno Maresca -- Cellular adaptation to amino acid availability: Mechanisms involved in the regulation of gene expression and protein metabolism / Sylvie Mordier, Alain Bruhat, Julien Averous and Pierre Fafournoux -- Amino acid-dependent signal transduction / Peter F. Dubbelhuis and Alfred J. Meijer -- Signal transduction pathways involved in the regulation of drug metabolizing enzymes / Vidya Hebbar and A.-N. Tony Kong -- Biological actions of infrared radiation / Lee Laurent-Applegate and Stéphanie Roques -- Energy sensing and photostasis in photoautotrophs / Norman P.A. Huner, Alexander G. Ivanov, Kenneth E. Wilson, Ewa Miskiewicz, Marianna Krol and Gunnar Öquist -- The uncoupling proteins family: From thermogenesis to the regulation of ROS / Marie-Clotilde Alves-Guerra, Claire Pecqueur, Alison Shaw, Elodi Couplan, Maria Del Mar, Gonzalez Barroso, Daniel Ricquier, Frédéric Bouillaud and Bruno Miroux -- Regulation of proliferation, differentiation and apoptosis of brown adipocytes : signal transduction pathways involved / Almudena Porras and Manuel Benito -- Control analysis of metabolic depression / R. Keira Curtis, Tammie Bishop and Martin D. Brand -- Evolution of physiological adaptation / Douglas L. Crawford -- Dynamic use of cDNA arrays : heterologous probing for gene discovery and exploration of organismal adaptation to environmental stress / Sean F. Eddy and Kenneth B. Storey.
  • Sensitivity and uncertainty analysis v. 1-2, 2003-05.
    v. 2, 2005 CRCnetBASE
    v. 1. Theory / Dan G. Cacuci -- v. 2. Applications to large-scale systems / Dan G. Cacuci, Mihaela Ionescu-Bujor, Ionel Michael Navon.
  • Sensory nerves 2009
  • "Sensory perception : mind and matter aims at a deeper understanding of the many facets of sensory perception and their relations to brain function and cognition. It is an attempt to promote the interdisciplinary discourse between the neurosciences and psychology, which speaks the language of cognitive experiences, and philosophy, which has been thinking about the meaning and origin of consciousness since its beginning. Leading experts contribute to such a discourse by informing the reader about exciting modern developments, both technical and conceptual, and by pointing to the big gaps still to be bridged. The various chapters provide access to scientific research on sensory perception and the mind from a broad perspective, covering a large spectrum of topics which range from the molecular mechanisms at work in sensory cells to the study of the unconscious and to neurophilosophy"--Publisher.
  • Applications of pressure cycling technology (PCT) in proteomics / Feng Tao ... [et al.] -- Applications of ion-exchange (IEX) chromatography to reduce sample complexity prior to two-dimensional gel electrophoresis (2DE) / Malcolm G. Pluskal, Eva Golenko, and Mary F. Lopez -- Separations in proteomics: use of camelid antibody fragments in the depletion and enrichment of human plasma proteins for proteomics applications / Mark ten Haaft, Pim Hermans, and Bruce Dawson -- Novel plasma protein separation strategy using multiple avian IgY antibodies for proteomic analysis / Sun W. Tam ... [et al.] -- Immunoaffinity depletion of high-abundant proteins for proteomic sample preparation / Nina Zolotarjova ... [et al.] -- Isolation of plasma membrane proteins for proteomic analysis / Catherine Fenselau and Amir Rahbar -- New ultrafiltration and solid phase extraction techniques improve serum peptide detection / Elena Chernokalskaya ... [et al.] -- Tools for sample preparation and prefractionation in two-dimensional (2D) gel electrophoresis / Anton Posch, Aran Paulus, and Mary Grace Brubacher -- Optic nerve fractionation for proteomics / Sanjoy K. Bhattacharya ... [et al.] -- Fractionation of retina for proteomic analyses / Sanjoy K. Bhattacharya ... [et al.] -- Reducing protein sample complexity with free flow electrophoresis (FFE) / Askar Kuchumov, Gerhard Weber, Christoph Eckerskorn -- Destreaking strategies for two-dimensional electrophoresis / Fengju Bai, Sheng Liu, and Frank A. Witzmann -- Proteomic approaches to the study of rheumatoid arthritis / Mikaela Antonovici ... [et al.] -- Immunoglobulin patterns in health and disease / Ingrid Miller and Marcia Goldfarb -- Difference gel electrophoresis (DIGE) / Mustafa Unlu and Jonathan Minden -- Principles and challenges of basic protein separation by two-dimensional (2D) electrophoresis / Anton Posch, Aran Paulus, and Mary Grace Brubacher -- Multidimensional separation of membrane proteins / Susan Francis-McIntyre and Simon J. Gaskell -- Structural approaches to glycoproteomics / Heidi Geiser, Cristina Silvescu, and Vernon Reinhold -- Enrichment and analysis of glycoproteins in the proteome / Nicole L. Wilson, Niclas G. Karlsson, and Nicolle H. Packer -- Proteomic analyses using high-efficiency separations and accurate mass measurements / Jon M. Jacobs and Richard D. Smith -- Middle-out proteomics: incorporating multidimensional protein fractionation and intact protein mass analysis as elements of a proteomic workflow / Scott J. Berger ... [et al.] -- Polymeric monolithic capillary columns in proteomics / Alexander R. Ivanov -- Proteins staining in polyacrylamide gels / Gary B. Smejkal -- Multiplexed proteomics: fluorescent detection of proteins, glycoproteins, and phosphoproteins in two-dimensional (2D) gels / Birte Aggeler-Schulenberg -- Glyoxyl agarose and its composite gels: advantageous alternatives to polyacrylamide gel electrophoresis for very large and small proteins and peptides and all sizes in between / John R. Shainoff -- Nuclear magnetic resonance-driven chemical proteomics: the functional and mechanistic complement to proteomics / Phani Kumar Pullela and Daniel S. Sem -- Electrophoretic nuclear magnetic resonance in proteomics: toward high-throughput structural characterization of biological signaling processes / Qiuhong He and Xiangjin Song.
  • Separation science and technology v. 1-, 1998-
  • Sepsis 2008
  • Roger C. Bone, MD and the evolving paradigms of sepsis / Balk, R. -- Clinical aspects of sepsis / Holub, M.; Závada, J. -- Virulence factors of gram-negative bacteria in sepsis with a focus on Neisseria meningitidis / Livorsi, D.J.; Stenehjem, E.; Stephens, D.S. -- Molecular mechanisms of sepsis / Russell, J.A. ... [et al.] -- Pro-inflammatory mechanisms in sepsis / Chong, D.L.W.; Sriskandan, S. -- Anti-inflammatory mechanisms of sepsis / Shubin, N.J.; Monaghan, S.F.; Ayala, A. -- Regulation of pro- and anti-inflammatory host responses / van der Poll, T.; van Zoelen, M.A.D.; Wiersinga, W.J. -- Future perspectives on regulating pro- and anti-inflammatory responses in sepsis / Delsesto, D., Opal, S.M.
  • Sepsis. 2nd ed. 2006
  • SAGE and LongSAGE / Annabeth Laursen Høgh and Kåre Lehmann Nielsen -- Robust-LongSAGE (RL-SAGE) : an improved LongSAGE method for high-throughput transcriptome analysis / Malali Gowda and Guo-Liang Wang -- aRNA LongSAGE : SAGE with antisense RNA / Anna M. Heidenblut -- SuperSAGE / Hideo Matsumura ... [et al.] -- Low-cost-medium throughput Sanger dideoxy sequencing / Kåre Lehmann Nielsen -- DeepSAGE : higher sensitivity and multiplexing of samples using a simpler experimental protocol / Kåre Lehmann Nielsen -- High-resolution, genome-wide mapping of chromatin modifications by GMAT / Tae-Young Roh and Keji Zhao -- 5'- and 3'-RACEfrom LongSAGE tags / Kåre Lehmann Nielsen -- Extraction and annotation of SAGE tags using sequence quality values / Jeppe Emmersen -- Correction of technology-related artifacts in serial analysis of gene expression / Viatcheslav R. Akmaev -- Duplicate ditag analysis in LongSAGE / Jeppe Emmersen -- Statistical comparison of two or more SAGE libraries : one tag at a time / Gerben J. Schaaf ... [et al.] -- Scaling of gene expression data allowing the comparison of different gene expression platforms / Fred van Ruissen ... [et al.] -- Clustering analysis of SAGE transcription profiles using a Poisson approach / Haiyan Huang, Li Cai, and Wing H. Wong -- Identifying nonspecific SAGE tags by context of gene expression / Xijin Ge and San Ming Wang.
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    v. 1. England and Wales, 1911-70 : Deaths and death rates by sex, age, site, and calendar period.
  • Pt. I. The psychology of serial violent crimes. Normalcy in behavioral characteristics of the sadistic serial killer / Jack Levin and James Alan Fox -- The compulsive-repetitive offender: behavioral patterns, motivational dynamics / Louis B. Schlesinger -- Serial juvenile sex offenders and their offenses / Jessica Woodhams, Clive Hollin and Ray Bull -- A study of offense patterns and psychopathological characteristics among recidivistic Finnish homicide offenders / Helinä Häkkänen -- Sensational and extreme interests in adolescents / Kathy E Charles and Vincent Egan -- Narcissism, sadism and loneliness: the case of serial killer Jeffrey Dahmer / George B. Palermo -- pt. 2. New dimensions to violent crime. Sexual homicide: an overview of contemporary empirical research / Leonard I. Morgenbesser and Richard N. Kocsis -- Serial killers and serial rapists: a preliminary comparison of violence typologies / Stacey L. Shipley and Bruce A. Arrigo -- Firesetting: a burning issue / Jeffrey L. Geller -- The 'gentler sex': patterns in female serial murder / Hannah Scott -- Anatomy of a mass murder: a psychological profile of Martin Bryant and the Port Arthur massacre / Ian Sale -- pt. 3. Investigative considerations to serial violent crimes. Blundering justice: a case study of the Schiedam Park Murder / Peter J. van Koppen -- Sexual (lust) homicide: definitional constructs, dynamics and investigative considerations / Janet McClellan -- Criminal profile construction and investigative procedures: a study of the Westley Dodd serial sexual murders / Ronald Turco -- Psychological skills and criminal profile accuracy / Erica P. Hodges and Kristine M. Jacquin -- Profiling and professionalization of criminal investigation / Jeffrey B. Bumgarner
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    Monograph 1. Unemployment insurance -- Monograph 2. Old age dependency -- Monograph 3. Health insurance -- Monograph 4. Social insurance legislation -- Monograph 5. The administration of unemployment insurance -- Monograph 6. The limitations of unemployment insurance -- Monograph 7-12. British experience with unemployment insurance -- Monograph 13. The problem of old age dependency.
  • Introduction -- Serotonin in the Nervous System of Vertebrates -- Nodal Structures in Anxiety-Like and Panic-Like Responses -- The Deakin-Graeff Hypothesis -- Topographic Organization of DRN -- General Conclusions.
  • Quantitative imaging of serotonin autofluorescence with multiphoton microscopy / S.K. Kaushalya and Sudipta Maiti -- Monitoring receptor-mediated changes of intracellular cAMP level by using ion channels and fluorescent proteins as biosensors / Evgeni G. Ponimaskin ... [et al.] -- Membrane organization and dynamics of the serotonin1A receptor monitored using fluorescence microscopic approaches / Shanti Kalipatnapu, Thomas J. Pucadyil, and Amitabha Chattopadhyay -- Calmodulin is a 5-HT receptor interacting and regulatory protein / Justin N. Turner ... [et al.] -- Identification of novel transcriptional regulators in the nervous system / Federico Remes-Lenicov ... [et al.] -- Serotonin 2A (5-HT2A) receptor function: ligand-dependent mechanisms and pathways / Ishier Raote, Aditi Bhattacharya, and Mitradas M. Panicker -- The 5-HT1A receptor: a signaling hub linked to emotional balance / Probal Banerjee, Mukti Mehta, and Baishali Kanjilal -- Do limits of neuronal plasticity represent an opportunity for mental diseases, such as addiction to food and illegal drugs? Use and utilities of serotonin receptor knock-out mice / Valerie Compan -- Use of mice with targeted genetic inactivation in the serotonergic system for the study of anxiety / Miklos Toth.
  • Introduction, Clinical and Technical Aspects-- Normal Cytology-- Reactive Mesothelial Hyperplasia-- Malignant Mesothelioma-- A Potential Litigation Diagnosis-- Metastatic Cancers-- Effusions in Children-- Abdominopelvic Washings-- Lymphocytic Effusions-- Benign Inflammatory and Other Uncommon Conditions-- Cerebrospinal Fluid.
  • Intracellular production of recombinant serpins in yeast / Dion Kaiserman ... [et al.] -- Production of recombinant serpins in Escherichia coli / Mary C. Pearce and Lisa D. Cabrita -- Isolation and characterization of the nuclear serpin MENT / Sergei Grigoryev and Sheena McGowen -- Solving serpin crystal structures / Randy J. Read, Aiwu Zhou, and Penelope E. Stein -- Crystallography of serpins and serpin complexes / M.A. Dunstone and James Whisstock -- Serpins as hormone carriers : modulation of release / Robin Carrell, Xiaoqiang Qi, and Aiwu Zhou -- Serpin-glycosaminoglycan interactions / Chantelle M. Rein, Umesh R. Desai, and Frank C. Church -- Targeting serpins in high-throughput and structure-based drug design / Yi-Ping Chang ... [et al.] -- Development of inhibitors of plasminogen activator inhibitor-1 / Shih-Hon Li and Daniel A. Lawrence -- Bioinformatic approaches for the identification of serpin genes with multiple reactive site loop coding exons / Stefan Börner and Hermann Ragg -- Methods to measure the kinetics of protease inhibition by serpins / Anita J. Horvath ... [et al.] -- Predicting serpin/protease interactions / Jiangning Song ... [et al.] -- Amino-Terminal Oriented Mass spectrometry of Substrates (ATOMS) : N-terminal sequencing of proteins and proteolytic cleavage sites by quantitative mass spectrometry / Alain Doucet and Christopher M. Overall -- Computational methods for studying serpin conformational change and structural plasticity / Itamar Kass, Cyril F. Reboul, and Ashley M. Buckle -- Probing serpin conformational change using mass spectrometry and related methods / Yuko Tsutsui, Anindya Sarkar, and Patrick L. Wintrode -- Determining serpin conformational distributions with single molecule fluorescence / Nicole Mushero and Anne Gershenson -- Serpin polymerization in vitro / James A. Huntington and Masayuki Yamasaki -- The serpinopathies : studying serpin polymerization in vivo / James A. Irving ... [et al.].
  • Sertoli cell biology 2005
  • Plasma biomarker discovery using 3D protein profiling coupled with label-free quantitation / Lynn A. Beer [and others] -- Intact protein separation by one- and two-dimensional liquid chromatography for the comparative proteomic separation of partitioned serum or plasma / Simon Sheng [and others] -- In-depth analysis of a plasma or serum proteome using a 4D protein profiling method / Hsin-Yao Tang, Lynn A. Beer, and David W. Speicher -- Intact-protein analysis system for discovery of serum-based disease biomarkers / Hong Wang and Samir Hanash -- Model-based discovery of circulating biomarkers / Maryann S. Vogelsang [and others] -- Low-molecular weight plasma proteome analysis using centrifugal ultrafiltration / David W. Greening and Richard J. Simpson -- High-throughput analysis of glycoproteins from plasma / Yan Li and Hui Zhang -- Minimizing preanalytical variation of plasma samples by proper blood collection and handling / Jizu Yi, David Craft, and Craig A. Gelfand -- Collection and handling of blood specimens for peptidomics / Harald Tammen and Rüdiger Hess -- Investigation of peptide biomarker stability in plasma samples using time-course MS analysis / Jizu Yi [and others] -- Biomarker validation in blood specimens by selected reaction monitoring mass spectrometry of N-glycosites / Reto Ossola [and others] -- Fluorescent microsphere-based method for assay of multiple analytes in plasma / Oliver K. Bernhard [and others] -- Immuno-mass spectrometry : quantification of low-abundance proteins in biological fluids / Vathany Kulasingam [and others] -- Qualitative and quantitative analysis of glycated proteins in human plasma by glucose isotopic labeling with 13C6-reducing sugars / Feliciano Priego-Capote [and others] -- Exosome isolation for proteomic analyses and RNA profiling / Douglas D. Taylor, Wolfgang Zacharias, and Cicek Gercel-Taylor -- Extraction and proteome analysis of liver tissue interstitial fluid / Wei Sun, Ying Jiang, and Fuchu He -- Protocol for the preparation of cryoprecipitate and cryodepleted plasma / Rosemary L. Sparrow, David W. Greening, and Richard J. Simpson -- Preparation of platelet concentrates / David W. Greening, Rosemary L. Sparrow, and Richard J. Simpson -- Phosphoproteome analysis of the platelet plasma membrane / Thomas Premsler [and others] -- Statistical design and analysis of label-free LC-MS proteomic experiments : a case study of coronary artery disease / Timothy Clough [and others] -- Data management in mass spectrometry-based proteomics / Lennart Martens -- Bioinformatics challenges in the proteomic analysis of human plasma / Joseph M. Foster and Lennart Martens -- Using the human plasma peptide atlas to study human plasma proteins / Terry Farrah, Eric W. Deutsch, and Ruedi Aebersold.
  • Pt.1. Summary of the Chicago Workshop -- Pt. 2. Summary of the Austin Workshop -- Pt.3. Summary of the Los Angeles Workshop -- Pt. 4. Summary of the Washington, D.C. Workshop
  • This book combines the instructive nature of a textbook with the visual aspects of an atlas to guide readers through the surgical principles, approaches, and techniques they need to dissect and clip cerebral aneurysms. Comprised of three concise sections, the book distills the distinguished author's vast experience into a series of easily accessible tutorials presented through clear, systematic descriptions and stunning, full-color illustrations. The first section explains the critical concepts and basic tenets of aneurysm microsurgery followed by a section on the various craniotomies and exposures necessary for successful clipping. The final section covers microsurgical anatomy, dissection strategies, and clipping techniques for each of the seven most common aneurysm types that are the focus of this book.
  • "The book is organized into three sections: tenets, the seven arteriovenous malformations, and selection. The tenets establish eight steps for AVM resection that comprise the phases of battle, as follows: step 1, exposure; step 2, subarachnoid dissection; step 3, defining the draining vein; step 4, defining the feeding arteries; step 5, pial dissection; step 6, parenchymal dissection;, step 7, ependymal or deep dissection; and step 8, finally resection. Critical concepts for dissection and resection are covered in the tenets section. In the section on the seven arteriovenous malformations, the anatomical battlefields for the lobes and deep regions are reviewed, 32 subtypes are described, and a resection strategy is presented for each subtype, step by step. The selection section addresses the secret to successful AVM surgery, which has nothing to do with surgical strategy or technique; rather, it is choosing your battles wisely"--Provided by publisher.
  • Introduction -- Primary treatment -- Definitive reconstruction -- Rehabilitation -- Treatment algorithm for missile open fractures of the limbs -- Conclusions.
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  • Children are no less spared from severe skin diseases. This textbook is designed as a practical clinical reference that will guide practitioners in treating difficult dermatoses in children in whom topical therapy has been unsuccessful. Individual sections are devoted to inflammatory diseases, immune-mediated/autoimmune diseases, tumors and proliferative disorders, and genodermatoses. Each chapter addresses which patients represent suitable candidates for systemic or other non-topical therapy and considerations and caveats in the use of such approaches. Potential treatments are then appraised from a current evidence-based perspective, with provision of detailed but relevant information and reference tables that summarize recommendations in use and monitoring. Future directions in management are also presented.
  • This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.
  • Section I. General Overview -- Chapter 1. Sex differences in brain anatomy / Eileen Luders, Arthur W. Toga -- Chapter 2 . Sex differences in the human brain: A developmental perspective / Tomáš Paus -- Chapter 3. Sex influences on brain and emotional memory: The burden of proof has shifted / Larry Cahill -- Chapter 4. Sexual differentiation of the human brain in relation to gender identity and sexual orientation / Ivanka Savic, Alicia Garcia-Falgueras, Dick F. Swaab -- Section II. The Mechanisms Behind Sex Dimorphism in the Brain -- Chapter 5. Genes and brain sex differences / Francisco J. Sánchez, Eric Vilain -- Chapter 6. Genetic and epigenetic underpinnings of sex differences in the brain and in neurological and psychiatric disease susceptibility / Irfan A. Qureshi, Mark F. Mehler -- Chapter 7. Gene expression in neuroendocrine cells during the critical period for sexual differentiation of the brain / Khatuna Gagnidze, Donald W. Pfaff, Jessica A. Mong -- Chapter 8. Neurosteroids: Endogenous role in the human brain and therapeutic potentials / Doodipala Samba Reddy -- Section III. Clinical Implications -- Chapter 9. Sex and gender differences in pain and analgesia / Jeffrey S. Mogil, Andrea L. Bailey -- Chapter 10. The skewed sex distribution in affective disorders: A diagnostic, social, or biological problem? / Marianne J. Legato -- Chapter 11. Empathizing, systemizing, and the extreme male brain theory of autism / Simon Baron-Cohen -- Chapter 12. Gender and the injured brain / Paco S. Herson, Patricia D. Hurn.
  • Sex differences in susceptibility to infection : an evolutionary perspective / Marlene Zuk and Andrew M. Stoehr -- Effects of sex steroids on innate and adaptive immunity / S. Ansar Ahmed, Ebru Karpuzoglu, and Deena Khan -- Sex steroid receptors in immune cells / Susan Kovats, Esther Carreras, and Hemant Agrawal -- Sex differences in susceptibility to viral infection / Sabra L. Klein and Sally Huber -- Sex differences in innate immune responses to bacterial pathogens / Jennifer A. Rettew, Ian Marriott, and Yvette M. Huet -- Sex hormones and regulation of host responses against parasites / James Alexander ... [et al.] -- Sex differences in parasitic infections : beyond the dogma of female-biased resistance / Galileo Escobedo, Marco A. De León, and Jorge Morale-Montor -- Progesterone, pregnancy, and innate immunity / Julia Szekeres-Bartho and Beata Polgar -- Pregnancy and susceptibility to parasites / Fiona L. Henriquez, Fiona M. Menzies, and Craig W. Roberts -- Sex steroids and risk of female genital tract infection / Patti Gravitt and Khalil Ghanem -- Sex, pregnancy, and measles / Allison C. Brown and William J. Moss -- Epilogue : challenges for the future / Craig W. Roberts and Sabra L. Klein.
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    Introduction: The Political Body -- Constructing Race -- Constructing Sex -- Placed Bodies -- Ambiguous Bodies -- The Examined Body -- The Unexamined Body -- The Diseased Body -- Conclusion: The Body Politic.
  • Update on diagnoses of sexual dysfunctions : controversies surrounding the proposed revisions of existing diagnostic entities and proposed new diagnoses / Balon, R. and Wise, T. -- Sexual desire and arousal disorders in women / Laan, E. and Both, S. -- Female orgasmic disorder / Rellini, A. and Clifton, J. -- Developments and trends in sex therapy / Meana, M. and Jones, S. -- The impact of cancer on sexual function / Morreale, M. -- Management of female sexual pain disorders / Boyer, S.C. ... [et al.] -- The impact of sexual trauma on sexual desire and function / McCarthy, B. and Farr, E. -- The complexity of Internet sexuality / Daneback, K. and Ross, M.W. -- Autogynephilia : an underappreciated paraphilia / Lawrence, A.A. -- Androgen deprivation treatment of sexual behavior / Houts, F.W. ... [et al.] -- Psychological and cross cultural aspects in infertility and human sexuality / Pacheco Palha, A. and Loureno, M.F.
  • Introduction : new developments in the area of sexual dysfunction(s) / R. Balon -- Clinical and research evaluations of sexual dysfunctions / L.R. Derogatis -- Management of hypoactive sexual desire disorder / R.T. Segraves -- Erectile dysfunction / K. Wylie -- Recent advances in the classification, neurobiology, and treatment of premature ejaculation / M.D. Waldinger -- The impact of physical illness on sexual dysfunction / A. Clayton, S. Ramamurthy -- The impact of mental illness on sexual dysfunction / Z. Zemishlany, A. Weizman -- Psychotropics and sexual dysfunction : the evidence and treatments / L.A. Labbate -- Drugs of abuse and sexual functioning / A. Pacheco-Palha, M. Esteves -- Contribution of imaging to our understanding of sexual function and dysfunction / T.L. Woodard, M.P. Diamond.
  • Sexual dysfunction presents a major challenge to physicians who take on the task of treating men with prostate cancer. While curing the disease and saving a life is paramount, improving technologies and therapies offer skilled surgeons and clinical oncologists the opportunity to eradicate the disease without compromising sexual function. In Sexual Function of the Prostate Cancer Patient, John Mulhall and a panel of internationally recognized experts on prostate cancer and sexual function assess in detail the current state of prostate cancer treatment. The authors offer a broad overview of the pathophysiology and treatment of erectile dysfunction in men with prostate cancer, reviewing the latest findings regarding erection-sparing radiation therapy and sexual function outcomes after laparascopic and robotic prostatectomy. Additional chapters discuss intra-operative maneuvers to minimize post-operative erectile dysfunction and pharmacologic penile preservation and rehabilitation. Timely and authoritative, Sexual Function in the Prostate Cancer Patient is a highly readable guide to preserving post-prostate cancer sexual function that no urologist or radiation and medical oncologist should be without.
  • A short reader for a holistic approach on human sexuality and its disorders -- Interdisciplinary references in sexual medicine -- Basic understanding of human sexuality -- The spectrum of sexual disorders -- Principles of diagnostics in sexual medicine -- Principles of therapy in sexual medicine -- New challenges for sexual medicine.
  • Diverse monogamies -- Multi-bonding: polygamy, polygyny, polyamory -- Child "partnering": incest, pedophilia, and child marriage -- Commercial partnering: sex work, trafficking, and pornography -- Object relations: fetish and related behaviors.
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    v. 1. Conceptual roots.--v.2 Ethical viewpoints in transition.
  • "These guidelines for the treatment of persons who have sexually transmitted diseases (STDs) were developed by CDC after consultation with a group of professionals knowledgeable in the field of STDs who met in Atlanta, Georgia, during April 19-21, 2005. The information in this report updates the Sexually Transmitted Diseases Treatment Guidelines, 2002 (MMWR 2002;51[No. RR-6]). Included in these updated guidelines are an expanded diagnostic evaluation for cervicitis and trichomoniasis; new antimicrobial recommendations for trichomoniasis; additional data on the clinical efficacy of azithromycin for chlamydial infections in pregnancy; discussion of the role of Mycoplasma genitalium and trichomoniasis in urethritis/cervicitis and treatment-related implications; emergence of lymphogranuloma venereum protocolitis among men who have sex with men (MSM); expanded discussion of the criteria for spinal fluid examination to evaluate for neurosyphilis; the emergence of azithromycin- resistant Treponema pallidum; increasing prevalence of quinolone-resistant Neisseria gonorrhoeae in MSM; revised discussion concerning the sexual transmission of hepatitis C; postexposure prophylaxis after sexual assault; and an expanded discussion of STD prevention approaches." - p. 1
  • I. Epidemiology, physiology and immunology. 1. Global epidemiology of sexually transmitted diseases / Anthony L. Cunningham, Adrian Mindel and Dominic E. Dwyer ; 2. The changing epidemiology of sexually transmitted diseases: the Russian experience / Mikhail Gomberg, Vagan A. Akovbian and Anna A. Koubanova ; 3. The genital tract: developmental, anatomical and microbiological factors affecting STD acquisition and strategies for prevention / Morris D. Cooper ; 4. Mucosal immunity of the genital tract / David I. Bernstein and Gregg N. Milligan -- II. Non-specific strategies for control. 5. Behavioral and psychological factors associated with STD risk / Susan L. Rosenthal, Sheila S. Cohen, and Frank M. Biro ; 6. Physical barrier methods: acceptance, use and effectiveness / Joseph Kelaghan ; 7. Topical microbicides / Penelope J. Hitchcock -- III. Pathogens and vaccines. 8. Genital and perinatal herpes simplex virus infections: prophylactic vaccines / Lawrence R. Stanberry ; 9. Therapeutic vaccines for control of herpes simplex virus chronic infections / Pierre Vandepapelière ; 10. Cytomegalovirus / John D. Shanley ; 11. Genital papillomavirus infection / Jessica L. Severson, Karl R. Beutner and Stephen K. Tyring ; 12. Therapeutic vaccines for control of human papillomavirus chronic infections / Pierre Vandepapelière ; 13. Hepatitis B virus infection / Jane N. Zuckerman and Arie J. Zuckerman ; 14. Therapeutic vaccines for chronic hepatitis B infection / Pierre Vandepapelière ; 15. Chlamydia / Robert C. Brunham and Grant McClarty ; 16. Gonorrhea: epidemiology, control and prevention / Jonathan M. Zenilman and Carolyn D. Deal ; 17 Syphilis / Adrian Mindel and Claudia Estcourt ; 18. HIV vaccines: milestones and new insights / Bonnie J. Mathieson -- Index.
  • Sexually Transmitted Diseases: A Practical Guide for Primary Care, Second Edition, covers the diagnosis and treatment of STDs and other information critical to patient care, and reflects the last five years of significant changes in information about STDs. Updated to reflect the 2010 Centers for Disease Control Guidelines on the Treatment of STDs, this book also contains new information about: -the epidemiology of herpes virus infections -expedited partner therapy -changes in recommendations for HPV vaccination for men -changes in resistance patterns for antimicrobial therapy for gonorrhea and chlamydia -treatment recommendations for genital warts In order to better meet clinician needs, the book has been streamlined to quickly convey critical, evidence-based information. Whether seeking information about particular conditions (including HPV, herpes, syphilis, trichomaniasis, HIV, and others) or related patient issues (such as STD exposure evaluation and evaluation of sexual assault), Sexually Transmitted Diseases, Second Edition, contains all the knowledge clinicians need in a friendly, to-the-point format.
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  • Comprehensive and complete, this book delivers the definitive, clinically oriented, cutting-edge guidance you need to achieve optimal outcomes managing the entire spectrum of gastrointestinal disorders. Make effective use of the latest endoscopic, robotic, and minimally invasive procedures as well as medical therapies with unbeatable advice from a "who's who" of international authorities! Shorten patient recovery time and lessen surgical risks using the latest minimally invasive and robotic techniques, including natural orifice translumenal endoscopic surgery, endoscopic plication for gastrointestinal reflux disease, and much more. Achieve total patient management by applying the newest pharmacologic treatments, including new drugs to be used alongside surgical therapies. Personalize treatments for IBD, cancer, and other inherited disorders with therapies based on genomics and proteomics. Take full advantage of the most recent advances in immunosuppression for transplant patients. Effectively treat diseases of the GI Tract with a comprehensive overview of both the basic science and the clinical information associated with surgery in this area.
  • Novalis® Shaped Beam Radiosurgery has set new standards by delivering highly precise radiation treatments to tumors anywhere in the body through the use of a proprietary multileaf collimator. By shaping the radiation beam to the exact contours of the tumor or lesion, Novalis permits maximum dose delivery to the entire tumor while protecting healthy tissue; this makes it eminently suitable for the treatment of irregularly shaped tumors. Novalis features 360° gantry rotation, stereoscopic kV X-ray imaging, and 6D robotic patient positioning. Dose delivery is typically achieved through fixed conformal beams, dynamic conformal arcs, and IMRT, and most brain treatments do not require an invasive head frame. This book provides a complete guide to radiosurgery treatments with Novalis. After a thorough discussion of the clinical and technical basis for Shaped Beam Radiosurgery, current clinical applications are considered in detail, including brain, body, skull base, and spinal tumors as well as arteriovenous malformations. Careful consideration is also given to future developments and applications, including new technologies that promise to offer even more accurate treatments. This state-of-the-art book will appeal to a wide audience of physicians and their multidisciplinary clinical and technical collaborators.
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  • Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health all possess large quantities of clinical research data. If these data were shared more widely within and across sectors, the resulting research advances derived from data pooling and analysis could improve public health, enhance patient safety, and spur drug development. Data sharing can also increase public trust in clinical trials and conclusions derived from them by lending transparency to the clinical research process. Much of this information, however, is never shared. Retention of clinical research data by investigators and within organizations may represent lost opportunities in biomedical research. Despite the potential benefits that could be accrued from pooling and analysis of shared data, barriers to data sharing faced by researchers in industry include concerns about data mining, erroneous secondary analyses of data, and unwarranted litigation, as well as a desire to protect confidential commercial information. Academic partners face significant cultural barriers to sharing data and participating in longer term collaborative efforts that stem from a desire to protect intellectual autonomy and a career advancement system built on priority of publication and citation requirements. Some barriers, like the need to protect patient privacy, present challenges for both sectors. Looking ahead, there are also a number of technical challenges to be faced in analyzing potentially large and heterogeneous datasets. This public workshop focused on strategies to facilitate sharing of clinical research data in order to advance scientific knowledge and public health. While the workshop focused on sharing of data from preplanned interventional studies of human subjects, models and projects involving sharing of other clinical data types were considered to the extent that they provided lessons learned and best practices. The workshop objectives were to examine the benefits of sharing of clinical research data from all sectors and among these sectors, including, for example: benefits to the research and development enterprise and benefits to the analysis of safety and efficacy. Sharing Clinical Research Data: Workshop Summary identifies barriers and challenges to sharing clinical research data, explores strategies to address these barriers and challenges, including identifying priority actions and "low-hanging fruit" opportunities, and discusses strategies for using these potentially large datasets to facilitate scientific and public health advances.
  • Chapter 1. Accessing Data -- Chapter 2. Creating Data Structures -- Chapter 3. Managing Data -- Chapter 4. Generating Reports -- Chapter 5. Handling Errors -- Chapter 6. Version 8.2 and Version 9.1 Enhancements.
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  • 1. Introduction -- 2. History and culture of tanning in the United States -- 3. Prevalence and correlates of indoor tanning -- 4. Motivation for indoor tanning: theoretical models -- 5. How ultraviolet radiation tans skin -- 6. Skin cancer and other health effects of indoor tanning -- 7. Tanning dependence: is tanning an addiction? -- 8. Selected indoor tanning myths and controversies -- 9. A systematic review of intervention efforts to reduce indoor tanning -- 10. Indoor tanning regulation, enforcement, taxation, and policy -- 11. Sunless tanning -- 12. International perspectives on indoor tanning -- 13. Indoor tanning: past, present, and future -- Index.
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  • Shengmai san 2002
    1. Shengmai San - a renowned traditional Chinese medicinal formula / Song-Ming Liang, Shu-Ying Chen, Si-Qian Liang -- 2. Pharmacological studies on Shengmai San / Kam-Ming Ko, Duncan H.F. Mak, Tze-Kin Yim and Yong-Quing Yan -- 3. Clinical studies on Shengmai San / Ye-Zhi Rong, Mei-Hua Zhao, Bao-Jing Lu, Xiang-Yang Zhu, Shang-Biao Lu, Ya-Chen Zhang, Jie Chen -- 4. Side effects of Shengmai San / Zhi-Min Xu and Ye-Zhi Rong -- 5. Phytochemistry and pharmacology of component herbs of Shengmai San / Siu-Po Ip, Timothy C.M. Tam and Chung-Tao Che -- 6. Contemporary applications of a traditional formula: manufacture of Shengmai San (SMS) preparations and their applications / Liang-Yuan Zheng -- Glossary.
  • Infection -- Infection: basic concepts -- Immune response to infection -- Sterilization, disinfection, and infection control -- Principles of laboratory diagnosis of infectious diseases -- Emergence and global spread of infection -- Pathogenic viruses -- Viruses: basic concepts -- Pathogenesis of viral infection -- Antiviral agents and resistance -- Influenza, parainfluenza, respiratory syncytial virus, adenovirus, and other respiratory viruses -- Viruses of mumps, measles, rubella, and other childhood exanthems -- Poxviruses -- Enteroviruses -- Hepatitis viruses -- Herpesviruses -- Viruses of diarrhea -- Arthropod-borne and other zoonotic viruses -- Rabies -- Retroviruses: human T-lymphotropic virus, human immunodeficiency virus, and acquired immunodeficiency syndrome -- Papilloma and polyoma viruses -- Persistent viral infections of the central nervous system -- Pathogenic bacteria -- Bacteria: basic concepts -- Pathogenesis of bacterial infections -- Antibacterial agents and resistance -- Staphylococci -- Streptococci and enterococci -- Corynebacterium, Listeria, and Bacillus -- Mycobacteria -- Actinomyces and Nocardia -- Clostridium, Peptostreptococcus, Bacteroides, and other anaerobes -- Neisseria -- Haemophilus and Bordetella -- Vibrio, Campylobacter, and Helicobacter -- Enterobacteriaceae -- Legionella and Coxiella -- Pseudomonas and other opportunistic gram-negative bacilli -- Plague and other bacterial zoonotic diseases -- Spirochetes -- Mycoplasma -- Chlamydia -- Rickettsia, Ehrlichia, Anaplasma, and Bartonella -- Dental and periodontal infections -- Pathogenic Fungi -- Fungi: basic concepts -- Pathogenesis and diagnosis of fungal infection -- Antifungal agents and resistance -- Dermatophytes, Sporothrix, and other superficial and subcutaneous fungi -- Candida, Aspergillus, Pneumocystis, and other opportunistic fungi -- Cryptococcus, Histoplasma, Coccidioides, and other systemic fungal pathogens -- Pathogenic parasites -- Parasites: basic concepts -- Pathogenesis and diagnosis of parasitic infection -- Antiparasitic agents and resistance -- Apicomplexa and microsporidia -- Sarcomastigophora: the amebas -- Sarcomastigophora: the flagellates -- Intestinal nematodes -- Tissue nematodes -- Cestodes -- Trematodes -- Glossary -- Infectious diseases: syndromes and etiologies.
  • Neck -- The Chest -- Emergency Department Thoracotomy -- Indications and Techniques for Trauma Laparotomy -- Indication and Techniques for Vascular Exploration -- Intubation, Cricothyrotomy, Tube Thoracostomy, Diagnostic Peritoneal Lavage, and Local Wound Exploration -- Ultrasound Physics for Point-of-Care Imaging: Performing the Various Exams with Technical Tips -- Trachea, Bronchus, and Esophagus -- The Lungs -- Cardiac Injury -- Liver Injuries -- The Spleen -- Pancreas and Duodenum -- Stomach, Small Bowel, and Colon -- Trauma of the Kidney, Ureter, Bladder -- Traumatic Injuries and Common Surgical Emergencies of the External Genitalia and Urethra.- Cervical Vascular Injuries -- Thoracic Vascular Injuries -- Endovascular Therapy in Trauma -- Timing of Fracture Fixation -- Treatment of Pelvic Fractures.
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  • Part 1. Administrative and Regulatory Issues / Society of Chest Pain Centers' Heart Failure Accreditation / Kay Styer Holmes and Arlene Mavko -- The Economics and Reimbursement of Congestive Heart Failure / Sandra Sieck -- Regulatory Requirements in Acute Heart Failure / Nancy M. Albert -- Quality and Operational Metrics in Heart Failure / Phillip D. Levy and Matthew A. Wheatley -- Interaction of Performance Measurements, Staffing, and Facility Requirements for the Heart Failure Observation Unit / Valorie Sweigart and Karen Krechmery -- Part 2. Pathophysiology and Demographics / Heart Failure: Epidemiology and Demographics / Karina M. Soto-Ruiz -- Pathophysiology of Acute Decompensated Heart Failure / Ezra A. Amsterdam, Kathleen L. Tong and Richard Summers -- Part 3. Emergency Medical Services and Emergency Department Assessment and Treatment / The Out-of-Hospital Management of Acute Heart Failure / Marvin A. Wayne, Vincent N. Mosesso and A. Keith Wesley -- Dyspnea Assessment and Airway Management in Acute Heart Failure Syndromes Patients / Masood Zaman and Peter S. Pang -- Volume Assessment in the Emergency Department / Anna Marie Chang and Judd E. Hollander -- Diagnostic and Prognostic Biomarkers in Emergency Department Heart Failure / Yang Xue, Arrash Fard, Navaid Iqbal and Alan Maisel -- Emergency Department Therapy of Acute Heart Failure / Phillip D. Levy -- Part 4. Observation Unit Entry Treatment and Disposition / Observation Unit Admission Inclusion and Exclusion Criteria / Gregory J. Fermann and Sean P. Collins -- Acute Heart Failure in Observation Unit Treatment Protocols / J. Douglas Kirk and Michael Clarke -- Education Elements in the Observation Unit for Heart Failure Patients / Robin J. Trupp -- Emergency Department and Observation Unit Discharge Criteria / Rachel Rockford and Deborah B. Diercks -- Effective Discharge Planning / Ginger Conway -- Outpatient Medication Titration in Acute Heart Failure / Khadijah Breathett and L. Kristin Newby -- Part 5. Complications and Future Research/ Drugs to Avoid in Acute Heart Failure: Contraindicated Medications and Interactions / James McCord -- Implications of Atrial Fibrillation in Heart Failure Management / Chad E. Darling and Richard V. Aghababian -- Implantable Cardiac Devices / Brian Hiestand and William Abraham -- Heart Failure and Kidney Disease: Management in the Short-Stay Unit / Shahriar Dadkhah and Korosh Sharain -- Heart Failure Research in the Emergency Department and Observation Unit / Candace McNaughton, Patricia Fick and Alan Storrow -- Appendix: Shared Practice Examples / Kay Styer Holmes.
  • Epidemiology and demography of coronary artery disease / S. Dadkhah and K. Sharain -- Financial impact of acute coronary syndromes: The need for new care delivery models / S. Sieck -- Why have a chest pain unit? / A. Annathurai and M.A. Ross -- Pathophysiology and definition of the acute coronary syndromes / E.A. Amsterdam, D. Diercks and J.D. Kirk -- Emergency department presentation / J.A. Holmes and S. Collins -- Risk stratification: History, physical, and EKG / A.B. Storrow, I. McClure and E. Harbison -- Cardiac markers: A chest pain center focus / R.H. Christenson -- Risk stratification using scoring systems / J.E. Hollander and A.M. Chang -- Emergency department disposition of patients presenting with chest pain / K. Owen and D.B. Diercks -- Short-stay unit requirements / L. Graff and iv -- Medical therapy in patients managed in a chest pain observation unit / J. McCord -- Provocative testing / J.D. Kirk, M.C. Kontos and E.A. Amsterdam -- Use of multislice CT and MRI for the evaluation of patients with chest pain / B. O'Neil, M.J. Gallagher and G.L. Raff -- Disposition from the short stay unit / C.A. Ghaemmaghami and W.J. Brady -- Examples of patient discharge instructions, ACS rule out protocols, and order sheets / K.S. Holmes.
  • Short stay surgery 2008
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    Dementia, delirium and other neuropsychiatric disorders -- Eating disorders and sleep disorders -- Psychiatry and medicine -- Suicide and deliberate self-harm -- The misuse of alcohol and drugs -- Problems related to sexuality and gender identity -- Psychiatry of the elderly -- Drugs and other physical treatments -- Psychological treatment -- Psychiatric services -- Child psychiatry -- Learning disability (mental retardation) -- Forensic psychiatry. Symptoms and signs of psychiatric disorders -- Classification and diagnosis -- Assessment -- Ethics and civil law -- Aetiology -- Evidence-based approaches to psychiatry -- Personality and personality disorder -- Reactions to stressful experiences -- Anxiety and obsessive-compulsive disorders -- Somatoform and dissociative disorders -- Mood disorders -- Schizophrenia -- Paranoid symptoms and delusional disorders --
  • Acromioplasty -- Rotator Cuff Repair: Open Technique for Partial-Thickness or Small or Medium Full-Thickness Tears -- Rotator Cuff Repair: Arthroscopic Technique for Partial-Thickness or Small or Medium Full-Thickness Tears -- Open Repair of Rotator Cuff Tears -- Arthroscopic Repair of Massive Rotator Cuff Tears -- Operative Fixation of Symptomatic Os Acromiale -- Humeral Head Resurfacing Arthroplasty -- Humeral Hemiarthroplasty with Biologic Glenoid Resurfacing -- Total Shoulder Arthroplasty -- Rotator Cuff Tear Arthroplasty: Open Surgical Treatment -- Open Unconstrained Revision Shoulder Arthroplasty -- Arthroscopic Treatment of Traumatic Anterior Instability of the Shoulder -- Open Treatment of Anterior-Inferior Multidirectional Instability of the Shoulder -- Arthroscopic Treatment of Anterior-Inferior Multidirectional Instability of the Shoulder -- Anterior Glenohumeral Instability Associated with Glenoid or Humeral Bone Deficiency: The Latarjet Procedure -- Open Treatment of Posterior-Inferior Multidirectional Shoulder Instability -- Arthroscopic Treatment of Posterior-Inferior Multidirectional Instability of the Shoulder -- Open Bankart Procedure for Recurrent Anterior Shoulder Dislocation -- Mini-Open Biceps Tenodesis -- Arthroscopic Biceps Tenodesis -- SLAP Lesion: Arthroscopic Reconstruction of the Labrum and Biceps Anchor -- Treatment of the Unstable Shoulder with Humeral Head Bone Loss -- Open Distal Clavicle Excision -- Arthroscopic Distal Clavicle Resection -- Open Treatment of Acute and Chronic Acromioclavicular Dislocations -- Sternoclavicular Joint Reconstruction Using Semitendinosus Graft -- Open Reduction and Internal Fixation of Acute Midshaft Clavicular Fractures -- Intramedullary Fixation of Clavicle Fractures -- Operative Treatment of Two-Part Proximal Humerus Fractures -- Open Reduction and Internal Fixation of Three- and Four-Part Proximal Humerus Fractures -- Percutaneous Fixation of Proximal Humerus Fractures -- Hemiarthroplasty for Proximal Humerus Fracture -- Surgical Treatment of Scapular Fractures -- Arthrodesis of the Shoulder -- Open and Arthroscopic Suprascapular Nerve Decompression -- Scapular Surgery I: Eden-Lange Transfer for Trapezius Muscle Palsy -- Scapular Surgery II: Pectoralis Major Transfer for Serratus Anterior Palsy -- Scapular Surgery III: Rhomboid/Latissimus Dorsi Transfer for Serratus Anterior Palsy -- Adhesive Capsulitis -- Arthroscopic Treatment of Calcific Tendinitis in the Shoulder -- Surgical Approaches for Open Treatment of the Elbow I: Posterior Approach -- Arthroscopy of the Elbow: Setup and Portals -- Elbow Arthritis and Stiffness: Open Treatment -- Elbow Arthritis and Stiffness: Arthroscopic Treatment -- Radial Head Fractures: Radial Head Replacement -- Total Elbow Arthroplasty: Discovery Minimally Constrained Linked System -- Total Elbow Arthroplasty for the Treatment of Complex Distal Humerus Fractures -- Hemiarthroplasty of the Distal Humerus -- Radiocapitellar Replacement -- Revision Total Elbow Arthroplasty -- Medial Epicondylitis: Open Treatment -- Lateral Epicondylitis: Arthroscopic and Open Treatment -- Repair of Distal Biceps Tendon Ruptures -- Repair and Reconstruction of the Ruptured Triceps -- Endoscopic Cubital Tunnel Release -- Submuscular Ulnar Nerve Transposition -- Surgical Decompression for Radial Tunnel Syndrome -- Distal Humerus Fractures, Including Isolated Distal Lateral Column and Capitellar Fractures -- Radial Head Fractures: Open Reduction and Internal Fixation -- Open Treatment of Complex Traumatic Elbow Instability -- Surgical Reconstruction of Longitudinal Radioulnar Dissociation (Essex-Lopresti Injury) -- Ulnar Collateral Ligament Reconstruction Using the Modified Jobe Technique -- Lateral Ulnar Collateral Ligament Reconstruction -- Soft Tissue Coverage I: Radial Forearm Flap -- Soft Tissue Coverage II: Latissimus Dorsi Flap -- Soft Tissue Coverage III: Posterior Interosseous Flap -- Soft Tissue Coverage IV: Brachioradialis Muscle Flap -- Soft Tissue Coverage V: Reverse Lateral Arm Flap -- Operative Treatment of Olecranon Bursitis -- Elbow Arthroscopic Débridement for Osteochondritis Dissecans.
  • Here is a technique textbook of shoulder arthroplasty detailing how to handle all relevant aspects of shoulder replacement surgery. Distinguished shoulder surgeons Gary M. Gartsman and T. Bradley Edwards provide step-by-step details for each category of shoulder arthroplasty, covering indications and contraindications, pre-operative planning and imaging, results and complications, and more. Copious color intraoperative photographs and illustrations and a bonus DVD of 17 surgical video clips of procedures discussed in the text complement the text.
  • This comprehensive and stunningly illustrated textbook covers the entire spectrum of shoulder disease and arthroscopic techniques. It reviews the anatomy and the biomechanics of the shoulder, basic arthroscopic procedures, advanced reconstructive surgeries, and an overview on shoulder pathologies with a special focus on surgical approach. Shoulder Arthroscopy: Principles and Practice is a highly organized reference with all chapters following a standardized format: from detailed descriptions regarding epidemiology, pathophysiology, clinical findings, imaging, indication for treatment up to a step-by-step description of current surgical techniques, including tips and tricks on how to avoid the most common mistakes and complications. There is also an entire section dedicated to the evaluation of outcome measurements. The tips and techniques presented in this book are based on the Editor and his Contributors' individual experience. The book guides the orthopaedic resident and fellow who wants to focus on shoulder diseases, but it also represents a landmark reference for expert surgeons already involved in shoulder surgery.
  • The new edition of this step-by-step guide covers the entire spectrum of operative shoulder arthroscopy from initial operation room set-up through advanced reconstructive procedures. View all-new illustrations and apply the latest treatment options for Bankart repair, SLAP repair, and repair of a full range of rotator cuff lesions, along with strategies for stiff shoulders and osteoarthritis. The included DVD narrated by Dr. Gartsman demonstrates exactly how to complete both simple and complex operations in over three hours of video clips. Whether you are a novice or an experienced shoulder surgeon, improve your technique with the expertise of Dr. Gartsman. Provides detailed step-by-step descriptions of Dr. Gartsman's approach-including variations and complications-so that you can reproduce his results. Includes a DVD with video clips of procedures demonstrating Dr. Gartsman's surgical techniques. Presents the most current scientific data on the treatment outcomes of specific.
  • The ISAKOS Upper Extremity Committee (UEC) meets on a biannual basis for Closed Consensus Meetings. Each summit, a worldwide expert panel of surgeons and researchers convene for an in-depth discussion about a controversial topic. The purpose of this endeavor is to combine expertise and reach international consensus for the most appropriate management of various shoulder disorders. This booklet constitutes an integral part of the agreement encountered during these meetings. Section A provides a comprehensive review of the currently available Classifications and Outcome Scores for shoulder disorders, illustrating their potential pitfalls and limitations. Section B presents a summary of the Acromio-Clavicular Joint (ACJ) Consensus Summit, describing pioneering techniques to re-establish shoulder function after dislocation. Section C describes the current state of evidence of Rotator Cuff Disorders, providing novel theories regarding its underlying biomechanics and reconstruction techniques. The 2009-2013 ISAKOS UEC members hope the readers find this compendium an insightful update for daily shoulder management.
  • Preconceptual risk factors / James A. O'Leary -- Antepartum risk factors / James A. O'Leary -- Role of ultrasound in shoulder dystocia / James A. O'Leary -- Intrapartum risk factors / James A. O'Leary -- Pelvimetry / James A. O'Leary -- Recognition of disproportion / James A. O'Leary -- Delivery techniques / James A. O'Leary -- The McRoberts maneuver / James A. O'Leary -- Cephalic replacement : the Gunn-Zavanelli-O'Leary maneuver / James A. O'Leary -- Infant injury / James A. O'Leary -- In utero causation of brachial plexus injury : myth or mystery? / James A. O'Leary -- Recurrent shoulder dystocia / James A. O'Leary -- Predisposing factors for shoulder dystocia-related birth injuries : causation analysis / Leslie Iffy, Joseph J. Apuzzio, and Vijaya Raju -- Recognition, classification, and management of shoulder dystocia : the relationship to causation of brachial plexus injury / Michael S. Kreitzer -- Minimizing the risks of shoulder dystocia-related fetal injuries / Leslie Iffy -- The maternal fetal medicine viewpoint : causation and litigation / Barry S. Schifrin and Wayne R. Cohen -- Brachial plexus injury at cesarean section / Michael S. Kreitzer and James A. O'Leary -- Delivery of the nondiabetic macrosomic infant / Lisa Gittens-Williams -- The midwifery view of shoulder dystocia / Judith S. Mercer and Debra A. Erickson-Owens -- Recent research : relevant and reliable / James A. O'Leary -- Observations on the etiology of brachial plexus birth palsy based on radiographic, intraoperative, and histologic findings / Stephen M. Russell, Israel Alfonso, and John A.I. Grossman.
  • "Shoulder Instability, by Drs. Mark Provencher and Anthony Romeo, is the first comprehensive resource that helps you apply emerging research to effectively manage this condition using today's best surgical and non-surgical approaches. Detailed illustrations and surgical and rehabilitation videos clearly demonstrate key techniques like bone loss treatment, non-operative rehabilitation methods, multidirectional instability, and more. You'll also have access to the full contents online at "-- Publisher's website.
  • Classification and Epidemiology: Classification of Stiff Shoulder -- Epidemiology. Etiology: Idiopathic -- Post-Traumatic -- Post Cuff Repair -- Post Instability Repair -- Other Post Surgical -- Other Causes (Cuff Disease, Impingement, Osteoarthritis, heterotopic ossification, etc). Anatomy and Biomechanics: Anatomy Related to the Range of Motion -- Biomechanics Related to the Range of Motion -- Rotator Interval and Stiffness. Examinations: Pathophysiology: Histology and Laboratory Tests -- Clinical Symptoms -- Physical Examinations -- Imaging. Conservative Treatment: Natural Course -- Conservative Treatment. Surgical Treatment: MUA -- Arthroscopic Release -- Postop. Rehabilitation Program -- Reported Outcomes and Results: What should we and the patient expect?.
  • Shoulder. 4th ed. v. 1, 2009
  • "Provides informed practical means of achieving and sustaining zero transmission. It is designed as a road map, providing direction and options from which to choose an appropriate path. The Prospectus reviews the operational, technical, and financial feasibility for those working on the front lines and outlines the tools that can be considered for an elimination program." "[summary]"--Provided by publisher.
  • Chapter 1. Introduction / Walter E. Goldstein -- Chapter 2. Epidemiology and Health Effects in Moisture-Damaged Damp Buildings / Jean Cox-Ganser, Ju-Hyeong Park, Richard Kanwal -- Chapter 3. Mold Biology, Molecular Biology and Genetics / Edward Sobek -- Chapter 4. Products of Mold Associated with Sick Building Syndrome / Walter E. Goldstein -- Chapter 5. Mathematical Model of Mold Propagation and Product Formation in Building Materials, Inherent Transport Phenomena and Applications / Walter E. Goldstein, Willem A. Schreuder -- Chapter 6. Forensic Studies in Moldy-Damp Buildings / Philip R. Morey, Gary N. Crawford, Michael J. Cornwell, Brad Caddick, Tara Toren-Rudisill, Raoul Webb -- Chapter 7. Practices in Identifying, Remediating and Reoccupancy When Mold Occurs / Gary R. Brown -- Chapter 8. Analysis of Microscopic Contaminants in Sick Building Investigations / James Millette, Barb Epstien, Elliott Horner -- Chapter 9. Analytical Practice in Mold Identification and Solutions, Including Measurements and Sampling / Edward Sobek -- Chapter 10. Research and Development, Directions in Construction Practice and Summary Recommendations / Walter E. Goldstein.
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  • This practical clinical handbook reveals that sickle cell disease (SCD) is an increasingly common condition to manage in Europe and North America. SCD demands clinical expertise and experience as well as sensitivity to its social and cultural context. This book is designed to broaden readersℓ́ℓ knowledge in this challenging condition by describing the acute and long-term complications unique to SCD and that affect nearly every system of the body. Critically, it also details the significant recent advances in understanding the pathophysiology of SCD that are leading to novel treatment modalities. ℗ℓ Sickle Cell Disease in Clinical Practice promotes higher quality care by outlining the clinical problems as they arise, and covering essential background information, including up-to-date research, and useful points to guide management. As such, the intended target audience is broad and includes general physicians, general practitioners, hematologists, pediatricians, emergency medicine physicians, surgeons, medical students, nurse specialists and commissioners.
  • Signal and image analysis techniques are becoming more widely used in biomedical and life science applications. With an emphasis on applications of computational models for solving modern challenging problems in biomedical and life sciences, this book aims to bring collections of articles from biologists, medical/biomedical and health science researchers together with computational scientists to focus on problems at the frontier of biomedical and life sciences. The goals of this book are to build interactions of scientists across several disciplines and to help industrial users apply advanced computational techniques for solving practical biomedical and life science problems. This book is for users in the fields of biomedical and life sciences who wish to keep abreast with the latest techniques in signal and image analysis. The book presents a detailed description to some of the applications. It can be used by those both at graduate and specialist levels.
  • Part I. Image Reconstruction and Restoration -- 1. Introduction to Image Reconstruction / Zhi-Pei Liang, Jim Ji, and E. Mark Haacke -- 2. Wavelet-Based Multiresolution Local Tomography / E. Rashid-Farrokhi and K.J.R. Liu -- 3. The Point Spread Function of Convolution Regridding Reconstruction / Gordon E. Sarty -- 4. Mapping Motion and Strain with MRI / Yudong Zhu -- 5. Rotational Motion Artifact Correction Based on Fuzzy Projection onto Convex Sets / Chaminda Weerasinghe, Lilian Ji, and Hong Yan -- 6. Tagged MR Cardiac Imaging / Nikolaos V Tsekos and Amir A. Amini -- 7. Functional MR Image Visualization and Signal Processing Methods / Alex R. Wade, Brian A. Wandell, and Thomas P. Burg --Part II. Image Segmentation and Analysis -- 8. Multiscale Segmentation of Volumetric MR Brain Images / Wiro J. Niessen, Koen L. Vincken, Joachim Weickert, and Max A. Viergever -- 9. A Precise Segmentation of the Cerebral Cortex from 3-D MRI Using a Cellular Model and Homotopic Deformations / Yann Cointepas, Isabelle Bloch, and Line Garnero -- 10. Feature Space Analysis of MRI / Hamid Soltanian-Zadeh -- 11. Geometric Approaches for Segmentation and Signal Detection in Functional MRI Analysis / Guillermo Sapiro -- 12. MR Image Segmentation and Analysis Based on Neural Networks / Javad Alirezaie and M.E. Jernigan -- 13. Stochastic Model Based Image Analysis / Yue Wang and Tiilay Adal -- 14. Functional MR Image Analysis -- Shang-Hong Lai and Ming Fang -- 15. Tagged MR Image Analysis / Amir A. Amini and Yasheng Chen -- Part III. Spectroscopic Signal Processing -- 16. Time-Domain Spectroscopic Quantitation / Leentje Vanhamme, Sabine Van Huffel, and Paul Van Hecke -- 17. Multidimensional NMR Spectroscopic Signal Processing / Guang Zhu and Yingbo Hua -- 18. Advanced Methods in Spectroscopic Imaging / Keith A. Wear -- 19. Characterization of Brain Tissue from MR Spectra for Tumor Discrimination / Paulo J.G. Lisboa, Wael El-Deredy, Y.Y. Barbara Lee, Yangxin Huang, Angelica R. Corona Herandez, Peter Harris, and Carles Aris -- 20. Wavelet Packets Algorithm for Metabolite Quantification in Magnetic Resonance Spectroscopy and Chemical Shift Imaging / Luca T Mainardi, Sergio Cerutti, Daniela Origgi, and Giuseppe Scotti -- 21. Cramér-Rao Bound Analysis of Spectroscopic Signal Processing Methods / Sophie Cavassila, Dirk van Ormondt, and Danielle Graveron-Demilly.
  • Lomb's algorithm and the Hilbert transform -- Modeling -- Volterra series -- Wiener series -- Poisson-Wiener series -- Decomposition of multichannel data -- Causality.
  • Chapter 1. Basic Tasks of Signal Processing in Spectroscopy -- Chapter 2. The Role of Quantum Mechanics in Signal Processing -- Chapter 3. Exact Quantum-Mechanical, Pade-Based Recovery of Spectral Parameters -- Chapter 4. Harmonic Transients in Time Signals -- Chapter 5. Signal-Noise Separation via Froissart Doublets -- Chapter 6. Machine Accurate Quantification and Illustrated Signal-Noise Separation -- Chapter 7. Pade Processing for MR Spectra from In Vivo Time Signals -- Chapter 8. Magnetic Resonance in Neuro-Oncology -- Chapter 9. Pade Quantification of Malignant and Benign Ovarian MRS Data -- Chapter 10. Breast Cancer and Non-Malignant Breast Data -- Chapter 11. Multiplet Resonances in MRS Data from Normal and Cancerous Prostate -- Chapter 12. Recapitulation of Pade-Optimized Processing of Biomedical Time Signals.
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  • [Publisher-supplied data] Unlike detecting constitutively expressed targets, immunohistochemical detection of labile, low abundance, and short-lived signal transduction molecules can be a very difficult task. In Signal Transduction Immunohistochemistry: Methods and Protocols, IHC experts contribute detailed protocols addressing the numerous challenges of signal-transduction immunohistochemistry (ST-IHC). Beginning with a set of introductory chapters, the volume moves on to cover techniques used for the preservation of antigens and their unmasking, protocols in digital imaging and image analysis of stained cells and tissues, high-throughput data collection and data analysis, and techniques used in neuroscience as well as cancer and stem cell research. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Signal Transduction Immunohistochemistry: Methods and Protocols serves as an ideal guide for novices and as a bastion of inspiring ideas to be exploited by experienced researchers on the lookout for new experimental tricks and hints.
  • "The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published, we take comprehensive review in regard with the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. Specifically, the initial stage of tumor metastasis will be highlighted. The complex tumor microenvironment accumulate a lot of growth factors, inflammatory cytokines and extracellular matrix which may turn into a group of potent metastatic factors. An integrated and sustained signaling induced by these metastatic factors may trigger EMT, migration and invasion of primary tumor into surround tissue. Blockade of these signal pathways is the most effective approach for prevention of tumor metastasis. A lot of clinical trials are under way for this purpose and the outcome are promising. The expert reviews compiled in this book may encourage the researcher in this exciting field for future study."--Back cover
  • G-protein-coupled receptor signaling -- Implication of G-proteins in cardiocascular diease / Madhu B. Anand-Srivastava -- B-adrenoceptor-linked signal transduction mechanisms in congestive heart failure / Melissa R. Dent...[et al.] -- Cardic G(alpha)s and G(alpha)i modualte sympathetic versus parasympathetic mechanisms on hyperhomocysteinemia / Thoma P. Vacek...[et al.] -- The role of the beta-adrenergic signal transduction pathway in myocardial protection / Johan Moolman...[et al.] -- Angiotensin II signaling in vascular physiology and pathophysiology / Neils Engberding, Kathy K. Greindling -- Angiotensin II signaling: cell growth and apoptosis / Stephen W. Shaffer, Mahmood S. Mozaffari -- Redox signaling -- Thioredoxin signaling in the ischemic heart / Dipak k. Das, Shyamal K. Goswami -- Relationship between redox regulation and B-adrenergic responses in the heart / Belma Turan -- Role of hyperglycemia and redox-induced signaling in vascular complications of diabetes / Ashok K. Srivastava, Madhu B. Anand-Srivastava -- Methylglyoxal and insulin resistance / Lingyun Wu -- Growth factor signaling -- Role of growth factor receptor transactivation in vasoactive peptide-induced signaling pathways in vascular smooth muscle cells / Ali Boullegue, Ashok K. Shrivastava -- Identifying the cellular and molecular events associated with the divergent phenotypes of cardic hypertrophy / Angelino Calderone -- Regulatory role of TGF-B in cardic myofibroblast function and post-MI cardic Fibosis: key roles of Smad7 and c-Ski / Ian M.C. Dixon...[et al.] -- The signaling duel between virus and host: Impact on Coxsackieviral Pathogenesis / Xiaonung Si...[et al.] -- Therapeutic angiogenesis and vasculogenesis for ischemic disease / Nilanjana Maulik -- VEGF signaling: a therapeutic target for cardiovascular disease / Dhanya Handrasekharan Rajalakshmi...[et al.] -- Myristoyl-CoA: protein N-Myristoyltransferase and Myristoyl-CoA binding protein from bovine cardiac muscle / Ponniah Selvakumar, Rajendra K. Sharma -- Calcium signaling -- Ca(2+)/calmodulin-dependent protein kinase II signaling in vascular smooth muscle / Suzanne J. House...[et al.] -- The KCa3.1 channel of endothelial cells as new target for EDHF-based control of cascular tone: from structure to regulation and pharmacological properties / Umberto Banderali...[et al.] -- Adipokine signaling -- Leptin signaling in the cardiovascular system / Morris karmazyn...[et al.] -- AMPK regulation of cardiac metabolism in heart disease / Ding An, Min-Suk Kim, Brian Rodigues.
  • Machine generated contents note: 1 Regulation of SignalTransduction by the Fcy Receptor Family -- Members and Their Involvement in Autoimmunity -- Coggeshall, K.M. (Oklahoma City, Okla.) -- 30 The Role ofTNF/TNFR in Organ-Specific and Systemic -- Autoimmunity: Implications for the Design of Optimized 'Anti-TNF' -- Therapies -- Kollias, G.; Kontoyiannis, D.; Douni, E.; Kassiotis, G. (Vari) -- 51 CD40 Signaling and Autoimmunity -- Cheng, G. (Los Angeles, Calif.); Schoenberger, S.P. (San Diego, Calif.) -- 62 TGF-j: Receptors, Signaling Pathways and Autoimmunity -- Chen, W; Wahl, S.M. (Bethesda, Md.) -- 92 lnterleukin-2 Signaling and the Maintenance of Self-Tolerance -- Nelson, B.H. (Seattle, Wash.) -- 113 Role of the B7-CD28/CTLA-4 Pathway in Autoimmune Disease -- Chang, T.T.; Kuchroo, VK.; Sharpe, A.H. (Boston, Mass.) -- 131 AbnormalT Lymphocyte Signal Transduction in Systemic Lupus -- Erythematosus -- Kammer, G.M. (Winston-Salem, N.C.); Tsokos, G.C. -- (Bethesda, Md./Silver Spring, Md.) -- 151 Lyn/CD22/SHP-1 and Their Importance in Autoimmunity -- Blasioli, J.; Goodnow, C.C. (Canberra) -- 161 Regulation of Immune Responses by E3 Ubiquitin-Protein Ligases -- Fang, N.; Fang, D.; Wang, H.-Y.; Altman, A.; Liu, Y.-C. (San Diego, Calif.) -- 176 Keeping theT-Cell Immune Response in Balance: Role of Protein -- Tyrosine Phosphatases in Autoimmunity -- Mustelin, T. (La Jolla, Calif.) -- 191 Author Index -- 192 Subject Index.
  • 2009 ClinicalKey
    "A reference on cellular-signalling processes, Signal Transduction second edition details the sources, key observations, and experiments that set the scene for recent and current scientific endeavour. Beginning with a historical overview, this book discusses how the concept of chemical messengers arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, and growth factors." "The book further examines more complex signalling cascades, emanating from classic receptors, as well as adhesion molecules, involved in processes such as vision, smell, inflammation, innate and adaptive immunity, glucose homeostasis, cell-fated decisions, cell differentiation, and cell transformation. This revision concludes with a discourse on the targeting of signal-transduction cascades in the treatment of cancer and the structure of protein domains key to the assembly of signalling complexes"--Book jacket.
  • Assessing the response of cells to TLR stimulation / Kiyoshi Takeda, Masahiro Yamamoto, and Kenya Honda -- TLR ligands in experimental settings their purity and specificity / Min-Fu Tsan -- Analysis of TLR expression, regulation, and signaling / Hui Xiao, Xiaoxia Li, and Derek W. Abbott -- Intracellular trafficking of toll-like receptors / Harald Husebye ... [et al.] -- The role of small RhoGTPases in TLR signaling / Monica Ruse and Ulla G. Knaus -- Use of engineered [beta]-lactamase fragment complementation to detect the associations of toll-like receptors and signaling adaptors / Hyun-Ku Lee and Peter S. Tobias -- Use of toll-like receptor chimeras to dissect mechanisms of receptor localization and signaling / Tadashi Nishiya and Anthony L. DeFranco -- Engagement of toll-like receptors modulates chemokine receptor signaling / Chong-Shan Shi and John H. Kehrl -- Role of toll-like receptor signaling in central nervous system infections / Tammy Kielian -- The influence of injury on toll-like receptor responses / Thomas J. Murphy ... [et al.].
  • Tools to Study Signaling -- Cell-Cycle Signaling, Epigenetics, and Nuclear Function -- Signaling in the Endothelium -- Rapid Signaling Pathways -- Growth Factors Signaling -- Ion Signaling and Electrophysiological Function -- Lipid Signaling Pathways in the Heart -- Heart Mitochondria: A Receiver and Integrator of Signals -- Signaling Pathways in Cardiovascular Development -- Signaling in Congenital Heart Disease -- Signaling in the Aging Heart -- Signaling in Endomyocarditis -- Signaling in Hypertension -- Gene Expression and Signaling Pathways in Myocardial Ischemia -- Signaling in Hypertrophy and Heart Failure -- Signaling in Diabetes and Metabolic Syndrome -- Dysrhythmias/Channelopathies and Signaling Pathways -- Signaling in Atherosclerosis -- Stem Cells Signaling Pathways in the Heart -- Cardioprotection and Signaling Pathways -- Targeting Signaling Pathways -- Signaling and the Frontiers Ahead.
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    Targeting receptor tyrosine kinase mutations in cancer / Mark Pearson and Doriano Fabbro -- The RET proto-oncogene: a valuable target for thyroid cancer therapy / Brigitte M. Pützer -- Inhibitors of HER/erbB receptors: biological bases and clinical applications / Vincenzo Damiano ... [et al.] -- Phosphatases as promising targets for cancer therapy / Marc Creus and Heinz Zoller -- Targeting the mTOR pathway for cancer therapy / Sabita Sankar -- Targeting MAP kinase signaling pathways for the treatment of cancer / Maria Julia Marinissen and Mario Chiariello -- Cell death-based therapy / Gerolama Condorelli ... [et al.] -- Signaling molecules and therapeutic targets in gliomas / Hrvoje Miletic, Parisa Monfared and Andreas H. Jacobs -- Identifying and targeting genes involved in childhood leukemia / Jenny Yeung and Hugh J.M. Brady -- Receptor binding peptides for receptor mediated endoradiotherapy in oncology / Walter Mier, Uwe Haberkorn and Michael Eisenhut.
  • This work presents the most advanced discoveries from translational research laboratories directly involved in identifying molecules and signalling pathways that play an instrumental role in metastasis. In contrast to other works, conventionally focused on a single type of tumour, the various chapters in this book provide a broad perspective of the similarities and discrepancies among the dissemination of several solid malignancies. Through recurrent and overlapping references to molecular mechanisms and mediators, the readers will gain knowledge of the common ground in metastasis from a single source. Finally, an introductory chapter provides a clinical perspective of the problems presented by metastatic tumours for diagnosis and treatment. The work presented here is directed to researchers in tumour biology with a developing interest in metastatic dissemination as well as medical and graduate students seeking to expand and integrate the notions acquired in basic cancer biology and oncology courses.
  • This text describes research suggesting that abnormal activation of signaling pathways is a critical event in cancer pathogenesis, and describes the emerging ability to design small molecules, protein therapeutics, and other forms of targeted cancer therapies.
  • 1. Abdominal Pain -- 2. Abnormal Vaginal Bleeding -- 3. Amenorrhea -- 4. Anemia -- 5. Anxiety -- 6. Arthralgia -- 7. Back Pain -- 8. Behavior Problems in Children -- 9. Bleeding and Bruising -- 10. Blood in Stool -- 11. Breast Masses and Nipple Discharge -- 12. Chest Pain -- 13. Child Abuse -- 14. Confusion -- 15. Congestion -- 16. Cough -- 17. Depression -- 18. Diarrhea -- 19. Dizziness -- 20. Earache -- 21. Family Discord -- 22. Fatigue -- 23. Fever -- 24. Headache -- 25. Health Maintenance -- 26. Heartburn -- 27. Hypertension -- 28. Jaundice -- 29. Lower Extremity Pain and Swelling -- 30. Lymphadenopathy -- 31. Menopause --- 32. Neck Pain -- 33. Pelvic or Genital Pain -- 34. Polyuria -- 35. Rashes -- 36. Seizures -- 37. Sexual Dysfunction -- 38. Shortness of Breath -- 39. Sleep Disorders -- 40. Sore Throat -- 41. Substance Abuse -- 42. Urinary Problems -- 43. Vaginal Discharge -- 44. Generalized Weakness -- 45. Weight Change
  • Eyelids -- Orbit -- Conjunctiva -- Episclera and sclera -- Cornea -- Anterior chamber -- Intraocular pressure and angle -- Iris -- Pupils -- Lens -- Vitreus -- Optic nerve head -- Fundus -- Ocular motility -- Systemic signs.
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  • Companion videos presents step-by-step procedures for splinting, arthrocentesis, injections, and reduction of fractures and dislocations. The book's Fracture Index illustrates every posssible fracturee of each bone.
  • The treatment of humeral fractures is a complex issue and the source of considerable controversy. In the case of fractures of the proximal humerus, early range of motion is the main aim of treatment. If a fracture modifies the anatomy or function of the glenohumeral and scapulothoracic joints, the surgeon must adhere meticulously to treatment principles in order to ensure a satisfactory outcome. Humeral shaft fractures are frequent, accounting for 1% to 3% of all fractures in adults; while excellent functional results have been reported with nonoperative management, open reduction and internal fixation is preferred in specific clinical settings. In contrast, intra-articular fractures of the distal humerus are frequently complex and full functional recovery is difficult to achieve. This volume clearly explains the concepts that are central to an understanding of humeral fractures from the proximal to the distal tip. Indications for different forms of treatment, including nonsurgical, are presented in detail, and all of the commonly used fixation techniques are described with the help of high-quality illustrations. Further important aspects such as complications, rehabilitation, and treatment of sequelae are also fully considered. This book will be an invaluable and comprehensive aid for all surgeons who treat humeral fractures.
  • Fundamental concepts of descriptive psychopathology -- Eliciting the symptoms of mental illness -- Consciousness and disturbed consciousness -- Attention, concentration, orientation, and sleep -- Disturbance of memory -- Disorder of time -- Pathology of perception -- Delusions and other erroneous ideas -- Disorder of the thinking process -- Disorder of speech and language -- Insight -- The disordered self -- Depersonalization -- Disorder of the awareness of the body -- The psychopathology of pain -- Affect and emotional disorders -- Anxiety, panic, irritability, phobia, and obsession -- Disorders of volition and execution -- The expression of disordered personality -- Psychopathology and diagnosis.
  • Lessons Learned from the Aviation Industry: Surgical Checklists / Stig Müller and Hitendra R. H. Patel -- Human Factors, Nontechnical Skills, and Surgical Training / Stig Müller, Waleed Al-Singary and Hitendra R. H. Patel -- Current State of Laparoscopic and Robotic Surgery / Jens J. Rassweiler, Marcel Hruza, Thomas Frede and Salvatore Micali -- Simulation and Training in Minimally Invasive Surgery / Sonal Arora, Shabnam Undre and Roger Kneebone -- Value of Virtual Reality in Medical Education / Amina A. Bouhelal, Hitendra R. H. Patel and Bijendra Patel -- The MIMIC Virtual Reality Trainer: Stepping into Three-Dimensional, Binocular, Robotic Simulation / Steven M. Lucas and Chandru P. Sundaram -- Laparoscopic Cholecystectomy Skills Acquisition and Procedural Proficiency in Novices Using Virtual Reality / Amina A. Bouhelal, Hitendra R. H. Patel and Bijendra Patel -- Lesson Learnt from the Military Surgeons Using Simulation in Trauma Surgery / Simon S. Fleming and John-Joe Reilly -- Clinical and Educational Benefits of Surgical Telementoring / Knut Mague Augestad, Taridzo Chomutare, Johan G. Bellika, Andrius Budrionis and Rolv-Ole Lindsetmo, et al. -- Portable Learning and Multimedia in Surgical Training / Narinderjit Singh Kullar, Stig Müller and Hitendra R. H. Patel.
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  • Sine syndromes (SSs) represent atypical forms of inflammatory rheumatic diseases, the courses of which are often severe. While the diagnosis of rheumatic diseases can be determined according to an established set of diagnostic criteria based on clinical characteristics and laboratory parameters, Sine Syndromes do not fulfill the standard criteria used to assist in the classification of patients with rheumatological disorders. This concise book gives an overview of atypical courses in common inflammatory rheumatic diseases such as Wegener's granulomatosis, systemic sclerosis, Sjögren's syndrome, or systemic lupus erythematosus. Each chapter reviews similar cases reported in the literature and presents current data on treatment options. Drawing on their vast clinical experience, the editors provide a series of detailed case reports in order to illustrate the different types of disease. The book is intended to facilitate early diagnosis and effective therapy in patients where a schematic approach may not prove sufficient. Sine Syndromes in Rheumatology will serve as a useful and easily accessible reference for specialists in rheumatology as well as for practitioners in the fields of internal medicine, pediatrics, and orthopedics.
  • Noninvasive metabolic assessment of single cells / David K. Gardner -- Laser capture microdissection for analysis of single cells / Nobuki Nakamura ... [et al.] -- Fluorescence in situ hybridization (FISH) on single cells (sex determination and chromosome rearrangements) / Paul N. Scriven and Caroline Mackie Ogilvie -- Single cell PCR for PGD : methods, strategies, and limitations / Karen Sermon and Martine De Rycke -- Real-time quantitative PCR measurement of male fetal DNA in maternal plasma / Bernhard Zimmermann ... [et al.] -- Cell-free fetal DNA plasma extraction and real-time PCR quantification / Jill L. Maron, Kirby L. Johnson, and Diana W. Bianchi -- LATE-PCR and allied technologies : real-time detection strategies for rapid, reliable diagnosis from single cells / Kenneth E. Pierce and Lawrence J. Wangh -- Efficient isothermal amplification of the entire genome from single cells / Karen V. Schowalter, Jolene R. Fredrickson, and Alan R Thornhill -- Comparative genomic hybridization on single cells / Lucille Voullaire and Leeanda Wilton -- Generation of amplified RNAs and cDNA libraries from single mammalian cells / James Adjaye -- Real-time PCR to measure gene expression in single cells / Dagan Wells -- Gender determination and detection of aneuploidy in single cells using DNA array-based comparative genomic hybridization (array CGH) / Dong Gui Hui, Xin Yuan Guan, and Nicole Hussey -- Microarray technology for mutation analysis of low template DNA samples / Chelsea Salvado and David Cram.
  • The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author?s personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects. Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China.
  • Single Incision Laparoscopic and Transanal Colorectal Surgery provide a comprehensive and state-of-the art review of single incision laparoscopic and transanal colorectal surgery. The text concentrates on surgical techniques and tricks in single incision laparoscopic and transanal surgery with detailed descriptions of the techniques, as well as indications and limitations of the procedures. The newly available evidence on these procedures is emphasized and all procedures are richly illustrated with diagrams and photos. Written by experts in their fields, Single Incision Laparoscopic and Transanal Colorectal Surgery is a valuable resource for general surgeons, colon and rectal surgeons, laparoscopic GI surgeons, surgical residents and fellows in training interested in these two rapidly developing fields in colorectal surgery.
  • Single molecule biology 2009
    The "single molecule" paradigm / Alex E. Knight -- Single molecule studies of myosins / Rachel E. Farrow ... [et al.] -- Single molecule experiments and the kinesin motor protein superfamily : walking hand in hand / Lukas C. Kapitein and Erwin J.G. Peterman -- Force-generating mechanisms of dynein revealed through single molecule studies / Kazuhiro Oiwa and Hiroaki Kojima -- The bacterial flagellar motor / Yoshiyuki Sowa and Richard M. Berry -- Single molecule studies of chromatin structure and dynamics / Sanford H. Leuba and Laurence R. Brewer -- Single molecule studies of nucleic acid enzymes / Samir M. Hamdan and Antoine M. van Oijen -- Single molecule studies of prokaryotic translation / Colin Echeverría Aitken ... [et al.] -- Single ion channels / David Colquhoun, Remigijus Lape, and Lucia Sivilotti -- Single molecule fluorescence in membrane biology / Lydia M. Harriss and Mark I. Wallace -- Single molecule microarray analysis / Jan Hesse ... [et al.].
  • ch. 1. Single Molecule Detection in Liquids and on Surfaces under Ambient Conditions: Introduction and Historical Overview / Jörg Enderlein, Richard A. Keller and Christoph Zander, p. 1-19 -- ch. 2. Theoretical Foundations of Single Molecule Detection in Solution / Jörg Enderlein and Christoph Zander, p. 21-67 -- ch. 3. Conceptual Basis of Fluorescence Correlation Spectroscopy and Related Techniques as Tools in Bioscience / Jerker Widengren and Ülo Mets, p. 69-120 -- ch. 4. Surface-Enhanced Raman Scattering (SERS - A Tool for Single Molecule Detection in Solution / Katrin Kneipp, Harald Kneipp, Irving Itzkan, Ramachandra R. Dasari and Michael S. Feld, p. 121-144 -- ch. 5. Single Molecule Detection on Surfaces with the Confocal Laser Scanning Microscope / Martin Böhmer and Jörg Enderlein, p. 145-183 -- ch. 6. Spectroscopy of Individual Photosynthetic Pigment-Protein Complexes / J. Wrachtrup, T.J. Aartsma, J. Köhler, M. Ketelaars, A. M. van Oijen, M. Matsushita, J. Schmidt, C. Tietz and F. Jelezko, p. 185-229 -- ch. 7. Single Dye Tracing for Ultrasensitive Microscopy on Living Cells / Gerhard J. Schütz and Hansgeorg Schindler, p. 231-245 -- ch. 8. Single Molecule Identification in Solution: Principles and Applications / M. Sauer and C. Zander, p. 247-272 -- ch. 9. Studying Molecular Motors on the Single Molecule Level / Y. Ishii, A. H. Iwane, H. Yokota, Y. Inoue, T. Wazawa, M. Nishiyama, H. Tanaka, K. Kitamura and T. Yanagida, p. 273-292 -- ch. 10. The Chemistry of a Single Enzyme Molecule / Robert Polakowski, Michael Eggertson, Douglas B. Craig and Norman J. Dovichi, p. 293-301 -- ch. 11. Single Molecule Detection of Specific Nucleic Acid Sequences / Alonso Castro, p. 303-321 -- ch. 12. Single Molecule Detection in the Near-Infrared / Steven A. Soper, Musundi Wabuyele, Clyde V. Owens and Robert P. Hammer, p. 323-362.
  • Star polymer surface passivation for single-molecule detection / Jürgen Groll and Martin Moeller -- Azide-specific labeling of biomolecules by Staudinger-Bertozzi ligation: phosphine derivatives of fluorescent probes suitable for single-molecule fluorescence spectroscopy / Anirban Chakraborty ... [et al.] -- Preparation of fluorescent pre-mRNA substrates for an smFRET study of pre-mRNA splicing in yeast / John Abelson, Haralambos Hadjivassiliou and Christine Guthrie -- Nanovesicle trapping for studying weak protein interactions by single-molecule FRET / Jaime J. Benítez, Aaron M. Keller and Peng Chen -- Droplet confinement and fluorescence measurement of single molecules / Lori S. Goldner, Ana M. Jofre and Jianyong Tang -- Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs / Abhinav Nath ... [et al.] -- Single-molecule spectroscopy using microfluidic platforms / Samuel Kim and Richard N. Zare -- Detection of protein-protein interactions in the live cell plasma membrane by quantifying prey redistribution upon bait micropatterning / Julian Weghuber ... [et al.] -- Analysis of complex single-molecule FRET time trajectories / Mario Blanco and Nils G. Walter -- Single-molecule fluorescence studies of intrinsically disordered proteins / Allan Chris M. Ferreon ... [et al.] -- Measuring the energetic coupling of tertiary contacts in RNA folding using single molecule fluorescence resonance energy transfer / Max Greenfield and Daniel Herschlag -- A highly purified, fluorescently labeled in vitro translation system for single-molecule studies of protein synthesis / Jingyi Fei ... [et al.] -- Watching individual proteins acting on single molecules of DNA / Ichiro Amitani ... [et al.] -- DNA curtains for high-throughput single-molecule optical imaging / Eric C. Greene ... [et al.] -- Scanning FCS for the characterization of protein dynamics in live cells / Zdenĕk Petrás̆ek, Jonas Ries and Petra Schwille -- Observing protein interactions and their stoichiometry in living cells by brightness analysis of fluorescence fluctuation experiments / Yan Chen ... [et al.] -- Detection of individual endogenous RNA transcripts in situ using multiple singly labeled probes / Arjin Raj and Sanjay Tyagi -- Single mRNA tracking in live cells / Hye Yoon Park, Adina R. Buxbaum and Robert H. Singer -- Single-molecule sequencing: sequence methods to enable accurate quantitation / Christopher Hart ... [et al.] -- Real-time DNA sequencing from single polymerase molecules / Jonas Korlach ... [et al.].
  • Single-access laparoscopic surgery (SALS), performed using a single transumbilical access, has recently proved to bring advantages over other forms of laparoscopic surgery due to the reduction in the number of incisions and the consequent decrease in morbidity, less blood loss and postoperative pain. Furthermore, cosmesis may be improved because incision within the umbilicus renders surgery virtually scarless. Nevertheless, as with all new surgical concepts, questions may be raised regarding safety, usefulness, and appropriateness. This book analyzes the use of SALS for different indications and abdominal surgical procedures based on a careful literature review of the experience of the most important surgical teams employing this approach and also the authors' personal observations. The coverage is broad, encompassing, for example, the role of SALS in appendectomy, repair of abdominal wall defects, cholecystectomy, gastric surgery, nephrectomy, splenectomy, hemicolectomy, and pancreatic, liver, and gynecological surgery. Resident surgeons specializing in laparoscopy, researchers, and related healthcare professionals will find Single-Access Laparoscopic Surgery to be an invaluable source of information in an area which deserves to receive detailed attention.
  • Single-molecule measurement techniques are providing fundamental information on the structure and function of biomolecules and are becoming an indispensable tool to understand how proteins work. During the last two decades, this field has grown at an almost exponential rate in terms of biological and biophysical applications. Single-molecule techniques have opened new fields of science that are at the crossroads of several disciplines such as biology, physics, chemistry, material science and computer science. These methods are often the approach of choice to clarify and better understand the structure and function of single proteins. This volume consists of up-to-date and comprehensive reviews of important and timely applications of different biological problems tackled by single-molecule methods; it also covers basic principles of operation, experiment and theory.In Single-molecule Studies of Proteins, expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.
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    The new era of biology in singulo / T. Ha and P.R. Selvin -- Single-molecule FRET with total internal reflection microscopy / C. Joo and T. Ha -- In vitro and in vivo FIONA and other acronyms for watching molecular motors walk / P.R. Selvin, T. Lougheed, M.T. Hoffman, H. Park, H. Balci, B.H. Blehm, and E. Toprak -- Colocalization of fluorescent probes: Accurate and precise registration with nanometer resolution / L.S. Churchman and J.A. Spudich -- Alternating-laser excitation of single molecules / A.N. Kapanidis, M. Heilemann, E. Margeat, X. Kong, E. Nir, and S. Weiss -- Orientation and rotational motions of single molecules by polarized total internal reflection fluorescence microscopy / J.F. Beausang, Y. Sun, M.E. Quinlan, J.N. Forkey, and Y.E. Goldman -- Imaging gene expression in living cells at the single-molecule level / J. Xiao, J. Elf, G.-W. Li, J. Yu, and X.S. Xie -- Single-virus tracking in live cells / M.J. Rust, M. Lakadamyali, B. Brandenburg, and X. Zhuang -- Ultrasensitive imaging in live cells using fluorescent quantum dots / S. Courty and M. Dahan -- Imaging real-time gene expression in living systems / A.L. Wells, J.S. Condeelis, R.H. Singer, and D. Zenklusen -- Single-molecule imaging of stochastic signaling events in living cells / S. Matsuoka, Y. Miyanaga, T. Yanagida, and M. Ueda -- Fluorescence correlation spectroscopy in vitro and in vivo / E. Haustein and P. Schwille -- Optical traps to study properties of molecular motors / J.A. Spudich, S.E. Rice, R.S. Rock, T.J. Purcell, and H.M. Warrick -- High-resolution dual-trap optical tweezers with differential detection / C. Bustamante, Y.R. Chemla, and J.R. Moffitt -- Imaging and nanomanipulation of an actomyosin motor / S. Nishikawa, T. Komori, T. Ariga, T. Okada, M. Morimatsu, Y. Ishii, and T. Yanagida -- Single-molecule studies using magnetic traps / T. Lionnet, J.-F. Allemand, A. Revyakin, T.R. Strick, O.A. Saleh, D. Bensimon, and V. Croquette -- Probing polysaccharide and protein mechanics by atomic force microscopy / M. Rabbi and P.E. Marszalek -- Single-molecule analysis of nucleic acids and DNA-protein interactions using nanopores / M. Wanunu and A. Meller -- Single-molecule gold-nanoparticle tracking with high temporal and spatial resolution and without an applied load / A.R. Dunn and J. A. Spudich -- Advances in surface-based assays for single molecules / P.M. Fordyce, M.T. Valentine, and S.M. Block -- Hydrodynamic flow-stretching assay for single-molecule studies of nucleic acid-protein interactions / C.M. Schroeder, P.C. Blainey, S. Kim, and X.S. Xie.
  • Placement of endosseous implants in the posterior maxilla is often difficult because of a lack of supporting bone. Sinus augmentation procedures have therefore been extensively used for the treatment of the edentulous atrophic posterior maxilla prior to implant placement. This book describes in detail the most widely used sinus grafting techniques as well as some innovative variations, with full coverage of both lateral and crestal approaches. A key aim is to assist the practitioner in selecting the appropriate sinus grafting technique based on the evaluation of a number of parameters that are described in detail and codified in a simple and practical way. Up-to-date information is also provided on grafting materials and on potential complications of sinus augmentation procedures and their treatment.
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  • The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this large palette of methodologies scientists may experience difficulties to gather useful information{u2019}s scattered within the literature. This book aims to present the state of this field from basic mechanisms of site-directed modifications to their applications in a wide range of organisms such as bacteria, yeast, plants, insects, mammals. It will discuss the problems encountered when using the random integration strategy and present the recent advances made in targeted genome modification. Technologies based on Zinc Finger nucleases, Meganucleases, TALEN, CRE and FLP recombinase, {uF06A}C31 integrase, transposases and resolvases are fully detailed with their strengths and weaknesses. All these information{u2019}s will help students and experienced researchers to understand and choose the best technology for their own purposes.
  • The enormous initial mistake -- The origins of six sigma -- Evolution -- Revolution -- Paradox -- Action and reaction -- Close enough or on target? -- Make more-- faster! -- Case studies -- The camera always lies -- Keeping it simple -- Why use control charts? -- Average and range control charts -- Origins and theory -- Charts for individuals -- Practical considerations -- Improving laboratories -- Beyond compliance.
  • Sjögren's Syndrome is slowly being recognised as one of the most common auto-immune diseases, and considered pivotal in the spectrum of auto-immune disorders. Sjögren's Syndrome in Clinical Practice is a unique, concise book which explores important insights into Sjögren's links with other conditions and devotes itself to shedding new light on this disease. Aimed at young medics but also suitable for the informed lay reader, physicians and pharma, Sjögren's Syndrome in Clinical Practice will help with the diagnosis and treatment of this increasingly recognised disorder.
  • Introduction -- A Note from Sweden: Recollection of Henrik Sjögren -- Myths, Pearls, and Tips Regarding Sjögren's Syndrome -- Providing Information to Referring Physicians and Patients -- Current Concepts on Classification Criteria and Disease Status Indexes in Sjögren's Syndrome -- Histopathology and Glandular Biopsies in Sjögren's Syndrome -- Imaging Technology in Sjögren's Syndrome: Non-invasive Evaluation of the Salivary Glands -- Genomics and Viruses in Sjögren's Syndrome -- Autoantibodies and Autoantigens in Sjögren's Syndrome -- B-cell Epitopes of Sjögren's Syndrome-Related Autoantigens Ro/SSA and La/SSB -- Neurobiology and Hormonal Control of Lacrimal and Salivary Gland Function -- Overview of Management of Dry Eye Associated with Sjögren's Syndrome -- Pathogenesis: Emphasis on Dry Eye and the Role of the Lacrimal Functional Unit in Sjögren's Syndrome -- Oral and Dental Manifestations of Sjögren's Syndrome: Current Approaches to Diagnostics and Therapy -- Etiology and Pathogenesis of Sjögren's Syndrome with Special Emphasis on the Salivary Glands -- Otolaryngologic Manifestations of Sjögren's Syndrome -- Extraglandular Manifestations of Sjögren's Syndrome (SS): Dermatologic, Arthritic, Endocrine, Pulmonary, Cardiovascular, Gastroenterology, Renal, Urology, and Gynecologic Manifestations -- Therapy of Dermatologic, Renal, Cardiovascular, Pulmonary, Gynecologic, Gastro-enterologic, Urologic and Fibromyalgia Manifestations Including Special Considerations at the Time of Surgery -- Current Treatment of Extraglandular Manifestations with Disease-Modifying and Immunosuppressive Agents -- Lymphoproliferation and Lymphoma in Sjögren's Syndrome -- Fatigue, Dryness, and Quality of Life as Clinical Trial Outcomes in Primary Sjögren's Syndrome -- The Neurological Manifestations of Sjögren's Syndrome: Diagnosis and Treatment -- New Approaches for the Management of Dry Mouth in Sjögren's Syndrome in Japan -- New Approaches for the Management of Dry Mouth and Dry Eye in Sjögren's Syndrome in Japan Dry Eye Part -- Sjögren's Syndrome in Australia: Clinical Practice and Research -- Primary Sjögren's Syndrome: Report from India -- Sjögren's Syndrome in China -- Sjögren's Syndrome in China -- Sjögren's Syndrome in Israel: A Scientific Point of View -- Looking into the Future-The EULAR Disease Activity Scores: Toward a Consensual Evaluation of Primary Sjögren's Syndrome -- Looking into the Crystal Ball: Initiatives from the Sjögren's Syndrome Foundation That Will Impact Patient Care -- Biological Treatment for Sjögren's Syndrome -- Looking into the Future-Emerging Therapies Based on Pathogenesis -- Into the Future: Autonomic Neuropathy, MicroRNAs, and Gene Therapy.
  • Skeletal examination method -- Skull fractures -- Rib fractures -- Fractures of the vertebral column, sternum, scapulae, and clavicles -- Long bone fractures -- Healing and interpretation -- Natural disease may mimic child abuse.
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    Approach to trauma -- Trauma in adults : upper extremity -- Trauma in adults : axial skeleton -- Trauma in adults : lower extremity -- Trauma in children -- Imaging of fracture treatment and healing -- Approach to bone lesions -- Malignant and aggressive tumors -- Benign lesions -- Metastatic tumors -- Approach to joint disease -- Inflammatory arthritis -- Noninflammatory joint disease -- Developmental and congenital conditions -- Metabolic and systemic conditions -- Infection and marrow disease -- Postsurgical imaging.
  • An Epidemiological approach to forensic investigations of violations to international humanitarian and human rights law -- Differential diagnosis of skeletal trauma -- Blasting injuries -- Blunt force trauma -- Skeletal evidence of torture -- Sharp force trauma -- Gunfire injuries -- Variation in gunfire wounds by skeletal region.
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    v. 1. General principles, spine, pelvis -- v. 2. Upper extremity, lower extremity.
  • The history of fracture treatment -- Global burden of musculoskeletal injuries -- The challenges of orthopaedic trauma care in the developing world -- Biology and enhancement of skeletal repair -- Biomechanics of fractures -- Closed fracture management -- Principles and complications of external skeletal fixation -- Principles of internal fixation -- Evaluation and treatment of the multi-injured trauma patient -- Initial evaluation of the spine in trauma patients -- Damage control orthopaedic surgery : a strategy for the orthopaedic care of the critically injured patient -- Disaster management -- Occupational hazards in the treatment of orthopaedic trauma -- Medical management of the orthopaedic trauma patient -- Evaluation and treatment of vascular injuries -- Compartment syndromes -- Open fractures -- Soft tissue reconstruction -- Gunshot wounds and blast injuries -- Pathologic fractures -- Osteoporotic fragility fractures -- Surgical site infection prevention -- Diagnosis and treatment of complications -- Chronic osteomyelitis -- Nonunions : evaluation and treatment -- Physical impairment ratings for fractures -- Outcome assessment in orthopaedic traumatology -- Professionalism and the economics of orthopaedic trauma care -- Psychological, social, and functional manifestations of orthopaedic trauma and traumatic brain injury * -- Imaging of spinal trauma -- Pathophysiology and emergent treatment of spinal cord injury -- The timing of management of spinal cord injuries -- Craniocervical injuries -- Subaxial cervical spine trauma -- Thoracolumbar fractures -- Fractures in the ankylosed spine -- Osteoporotic spinal fractures -- Avoiding complications in spine trauma patients -- Principles of orthotic management -- Pelvic ring injuries -- Surgical treatment of acetabular fractures -- Fractures and dislocations of the hand -- Fractures and dislocations of the carpus -- Fractures of the distal radius -- Diaphyseal fractures of the forearm -- Trauma to the adult elbow and fractures of the distal humerus -- Fracture of the humeral shaft -- Proximal humerus fractures and glenohumeral dislocations -- Fractures and dislocations of the clavicle -- Scapula and rib fractures -- Replantation -- Hip dislocations -- Medical management of the patient with hip fracture -- Intracapsular hip fractures -- Intertrochanteric hip fractures -- Posttraumatic reconstruction of the hip joint -- Subtrochanteric fractures of the femur -- Femoral shaft fractures -- Fractures of the distal femur -- Patella fractures and extensor mechanism injuries -- Knee dislocations and soft tissue injuries -- Tibial plateau fractures -- Malunions and nonunions about the knee -- Tibial shaft fractures -- Fractures of the tibial pilon -- Malleolar fractures and soft tissue injuries of the ankle -- Foot injuries -- Posttraumatic reconstruction of the foot and ankle -- Periprosthetic fractures of the lower extremity -- Principles of deformity correction -- Limb salvage and reconstruction -- Amputations in trauma.
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    "What if what we consider to be reason-based, deliberative judgment is really the product of involuntary mental sensations? In A Skeptic's Guide to the Mind, Dr. Robert Burton takes a close look at the key false assumptions that permeate the field of cognitive science and offers a new way of exploring how our brains generate thought. The essential paradox that drives this cutting-edge theory is that the same mechanisms that prevent understanding the mind also generate a sense that we can attain such understanding. In A Skeptic's Guide to the Mind, Burton presents his theory of the 'mental sensory system'--a system that generates the main components of consciousness: a sense of self, a sense of choice and free will, and how we make moral decisions. Bringing together anecdotes, practical thought experiments, and cutting-edge neuroscience to show how these various strands of thought and mental sensations interact, A Skeptic's Guide to the Mind offers a powerful tool for knowing what we can and cannot say about the mind; how to discern good from bad cognitive science studies; and most importantly, how to consider the moral implications of these studies. This is a pathbreaking model for considering the interaction between conscious and unconscious thought."-- Provided by publisher.
  • Skin aging 2006
    1. Recent Demographic Changes and Consequences for Dermatology / Ursula Krämer and Tamara Schikowski, p. 1-8 -- 2. Clinical and Histological Features of Intrinsic versus Extrinsic Skin Aging / Mina Yaar, p. 9-21 -- 3. Ethnic Differences in Skin Aging / Erwin Tschachler and Frederique Morizot, p. 23-31 -- 4. Photoaging of Skin / Jean Krutmann and Barbara Gilchrest, p. 33-43 -- 5. Premature Skin Aging by Infrared Radiation, Tobacco Smoke and Ozone / Peter Schroeder, Stefan Schieke and Akimichi Morita, p. 45-53 -- 6. The Role of Hormones in Intrinsic Aging / Christos Zouboulis and Evgenia Makrantonaki, p. 55-64 -- 7. Permeability and Antioxidant Barriers in Aged Epidermis / Jens Thiele, Chantal Barland, Ruby Ghadially and Peter Elias, p. 65-79 -- 8. Clarifying the Vitamin D Controversy: The Health Benefits of Supplementation by Diet Versus Sunshine / Deon Wolpowitz and Barbara Gilchrest, p. 81-102 -- 9. Modern Photoprotection of Human Skin / Jean Krutmann and Daniel Yarosh, p. 103-112 -- 10. Vitamins and Polyphenols in Systemic Photoprotection / Wilhelm Stahl, Hasan Mukhtar, Farrukh Afaq and Helmut Sies, p. 113-121 -- 11. Hormone Replacement Therapy and Skin Aging / Glenda Hall and Tania Phillips, p. 123-132 -- 12. Skin Aging in Three Dimensions / Niels Krejci-Papa and Robert Langdon, p. 133-142 -- 13. Retinoid Therapy for Photoaging / Laure Rittié, Gary Fisher and John Voorhees, p. 143-156 -- 14. Topical Photodynamic Therapy / Dany Touma and Rolf-Markus Szeimies, p. 157-166 -- 15. Botulinum Toxin, Fillers, Peels: The Scientific View / Nanna Schürer, p. 167-184 -- 16. Lasers / Roland Kaufmann and Christian Beier, p. 185-194.
  • 1. Structure and functionality of the skin / Ichiro Hatta -- 2. Response for external stimulation on the skin / Masaki Ujihara and Toyoko Imae -- 3. Beautification of the skin / Satoshi Amano, Tomonobu Ezure, and Toshii Iida -- 4. Skin bioscience : a molecular approach / Yoshimitsu Kuroyanagi.
  • Biopsy techniques and interpretation / Deborah F. MacFarlane and Ronald P. Rapini -- Topical therapies for nonmelanoma skin cancers / Abel Torres and Tejas Desai -- Chemical peels for precancerous skin lesions / Gary D. Monheit and Chad L. Prather -- Photodynamic therapy / Nathalie C. Zeitouni, Allan Oseroff, and David J. Najarian -- Intralesional and perilesional treatment of skin cancers / Christopher J. Arpey, Nicole M. Annest, Stephen B. Tucker, Ronald P. Rapini, and Deborah F. MacFarlane -- Electrodesiccation and curettage / Gloria F. Graham -- Cryosurgery / Gloria F. Graham -- Optimizing surgical outcomes / Thomas Stasko and Amy Ross -- Anesthesia / Susannah L. Collier and George J. Hruza -- Excision techniques, staples, and sutures / Mollie A. MacCormack -- Mohs surgery / Desiree Ratner and Jennifer L. MacGregor -- Cutaneous flaps / Tatyana Humphreys -- Techniques in skin grafting / Deborah F. MacFarlane -- Nail surgery and malignant tumors of the nail unit / Deborah F. MacFarlane and Richard K. Scher -- Practical management of melanoma / Mark F. Naylor -- Skin cancer in skin of color / Brooke A. Jackson -- Management of skin cancers in solid organ transplant recipients / John Carucci and Dariush Moussai -- Imaging of head and neck skin cancer / Komal Shah, Jane Onufer, and Deborah F. MacFarlane -- Radiation oncology in skin cancer treatment / Susan L. McGovern and Matthew T. Ballo -- When to refer out / Daniel M. Siegel, Laura T. Cepeda, and Deborah F. MacFarlane -- Chemoprevention of skin cancer / Fiona Zwald and David Lambert.
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  • Skin Cancer: A Practical Approach presents a comprehensive and up to date overview on skin cancer. With an emphasis on practical aspects that will set the basis for guidelines of treatment, the volume presents different diagnostic tools to help physicians obtain the proper diagnosis. Written by a worldwide base of experts selected on their recognized expertise on the different themes discussed, Skin Cancer: A Practical Approach is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, dermatologists, general surgeons, and veterinary oncologists.
  • The dramatic increase in the incidence of skin cancers is a major concern worldwide and relates not only to melanoma but also to other cancers, including Merkel cell and basal cell carcinomas. Recently, the WHO has summarized the genetic and pathologic features of skin cancers in its book series. However, the WHO's proposed classification of certain disease entities, such as basal cell carcinomas, is still novel for many dermatologists. This book covers the entire spectrum of cutaneous malignancies in accordance with the new WHO classification. Epidemiology, pathogenesis, diagnosis, and therapy are all reviewed in detail, and care is taken to link the diagnostic and genetic features to optimized therapeutic strategies.-- Provided by publisher.
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  • As the number of surviving immune suppressed patients continues to rise, skin manifestations of patients have become increasingly important. AIDS patients, and renal, heart, liver, bone marrow, and lung transplant patients are now living longer and immunosuppressive drugs are being used more frequently. Diabetes is rising in the US and around the world, offering its own unique brand of immune suppressed skin diseases. The skin may be the earliest sign of these conditions and be the organ showing the most profound, earliest, and treatment limiting side effects. Skin Diseases in the Immunocompromised is the most comprehensive book on the topic available. It elucidates the signs of immune suppressed skin diseases to afford early diagnosis and management of this ever-increasing diverse group of illnesses. Organized for easy access, this book will be an essential resource for residents and fellows in dermatology and infectious diseases medical professionals.
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  • Rheumatologic diseases are highly associated with clinical symptoms of the skin, nails, and mucosal membranes. This book provides the practicing rheumatologist with a rapid, easy to consult reference to help interpret the nature of these cutaneous lesions and then quickly decide upon the appropriate follow-up tests. Utilizing an abundance of informative photographs, it contains all of the essential information needed for early diagnosis and treatment. This comprehensive guide properly orients the practitioner within the challenging world of rheumatologic disorders of the skin and gives insight into when consultation with a dermatologist is advisable.
  • Skin necrosis 2015
    In recent years, wound care has gained increasing recognition as a distinct medical specialty. An understanding of the complex mechanisms involved in wound healing facilitates efficient assessment and treatment of patients with wounds, and skin necrosis can be considered the starting point in the entire healing process. This book is the first to discuss skin necrosis as a symptom related to a broad range of pathologies. Richly illustrated, it primarily provides therapeutic strategies and treatment algorithms for different clinical contexts. All chapters were written by renowned specialists in their respected fields and include detailed sample cases and essential take-home messages. In light of the highly interdisciplinary nature of wound management, Skin Necrosis offers an invaluable resource for wound care practitioners and health care professionals across the fields of surgery, dermatology, internal medicine, and nursing.
  • This book serves as a practical guide to the diagnosis and treatment of common skin disorders in patients with skin of color. Emphasizing practical insights into diagnosis and treatment of skin and hair disorders in darker skinned patient populations, Skin of Color offers a detailed discussion of the nuances of treating skin of color. Topics of discussion include: management of acne, keloids, melasma, postinflammatory hyperpigmentation, acne keloidalis nuchae, alopecias, and the safe and effective use of chemical peels, laser procedures, and injectable fillers and toxins in skin of color patients.
  • An era of global population aging is upon us. By 2030, one in eight people will be over age 65. Since women generally live longer than men, the health and welfare of postmenopausal women will become a significant public health concern. This book offers a comprehensive review of the life changes associated with menopause, both at the dermatological and physiological level (e.g., hormonal, immunological) and at the subcellular level. It critically examines the dermatological, biological, and clinical challenges to postmenopausal health and well-being and the current and emerging therapeutic interventions. The authors advocate a holistic approach, emphasizing the need to view the menopause as a life transition with various facets rather than as a series of distinct medical conditions to be managed. Our goal is to offer a comprehensive resource to the researchers, clinicians, physicians, and helping professions whose mission is to promote the health and well-being of women around the world.
  • Sleep and aging. 1st ed. 2005
  • Sleep and anesthesia resemble in many ways at a first glance. The most prominent common feature of course is the loss of consciousness, i.e. the loss of awareness of external stimuli. However a closer look at the loss of consciousness reveals already a difference between sleep and anesthesia: anesthesia is induced by an anesthetic drug whereas we may fall asleep without external cause. Other questions may arise about the difference of the two effects: do we dream during surgery under anesthesia, do we feel pain during sleep? Essentially, we may ask: what is common and what are the differences.
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  • GABA[subscript A] receptor subtypes in sedation and hypnosis / Esa R. Korpi -- Sleep hippocampal theta rhythm and sensory processing / Marisa Pedemonte and Ricardo A. Velluti -- Monoaminergic mechanisms in the regulation of sleep-wakefulness: special emphasis on preoptic noradrenergic system / Vijay Ramesh and Velayudhan Mohan Kumar -- REM sleep function and brain monoamine regulation: an application of the search activity concept / Vadim S. Rotenberg -- Role of wakefulness area in the brainstem reticular formation in regulating rapid eye movement sleep / Birendra N. Mallick ... [et al.] -- The mechanistic relationship between NREM sleep and anesthesia / Laura E. Nelson, Nicholas P. Franks, and Mervyn Maze -- Time-dependent psychotropic drug effects: hints of pharmacochronomics, broader than circadian time structures / Haruo Nagayama ... [et al.] -- Melatonin interaction with BZ-Gaba[subscript A] receptors: implications for sleep induction / Lennard P. Niles -- Melatonin: a chronobiotic that not only shifts rhythms / Dieter Kunz and Richard Mahlberg -- Melatonin and human sleep / Irina V. Zhdanova -- Melatonin efficacy to treat circadian alterations of sleep in Alzheimer's disease / Daniel P. Cardinali ... [et al.] -- Pharmacotherapy for seasonal affective disorder / Timo Partonen -- Use and discontinuation of hypnosedative medications / Mirko Petrovic -- Long-term use of sleeping pills in chronic insomnia / Milton Kramer -- Risks of chronic hypnotic use / Daniel F. Kripke -- Effects of psychotropics on driving performance / Henry J. Moller, Colin M. Shapiro, and Leonid Kayumov -- Diagnosis, pathophysiology and treatment of hypersomnias / Sebastiaan Overeem and Michel Billiard -- Chronic disease and sleep architecture pharmacotherapeutic considerations / James J. Herdegen -- Benzodiazepines for sedation in infants and children / Eugene Ng and Vibhuti Shah -- The pharmacological management of fatigue and sleepiness in affective disorders / Karl Doghramji -- Next-day residual effects of sleeping medications on driving ability: a review of the literature / Joris C. Verster, Marinus N. Verbaten, and Edmund R. Volkerts -- Sleep and pain / Wilfred R. Pigeon, Hyung Park, and Michael J. Sateia -- Head injuries and sleep / Chanth Seyone and Babita Kara -- Psychopharmacological management of restless legs syndrome and periodic limb movements in sleep / Raed Hawa ... [et al.] -- A comparison of visual analog scale and categorical ratings in assessing the patient's estimate of sleep quality / Nava Zisapel, Ricardo Tarrasch, and Moshe Laudon -- The pharmacostrategy of treating sleep disorders in Parkinsonism / Jean-Jacques Askenasy -- The neuropharmacology of nightmares / J.F. Pagel -- The night eating syndrome / Grethe Seta Birketvedt and Jon R. Florholmen -- Drug effects on dreaming / Mehmet Yucel Agargun and Hanefi Ozbek -- Sleep problems in primary care / Alan G. Wade -- SSRIs and sleep in man / Sue J. Wilson and David J. Nutt -- Sleep and antipsychotic drugs in schizophrenia patients / Jaime M. Monti and Daniel Monti -- Sleep and epilepsy: from interrelationships to influence of antiepileptic drugs / Antonio Martins da Silva ... [et all.] -- Herbal medicines and sleep / Marcello Spinella.
  • A multi-disciplinary approach that covers both the surgical and non-surgical interventions for sleep apnea and snoring. Full-color line drawings illustrate key concepts and create a comprehensive way of learning surgical techniques. Provides quick, easy access to the most up-to-date surgical and non surgical interventions for sleep apnea and snoring. Includes contributions from leaders in neurology, pulmonology, psychiatry, otolaryngology, and oral & maxillofacial surgery. Covers new and innovative procedures including ZPP (Zeta palatopharyngoplasty), Transpalatal Advancement Pharyngoplasty and Minimally invasive submucosal glossectomy. Details when and why surgery is necessary, and how to perform a successful operation for snoring and sleep apnea.
  • Electrical stimulation of the upper airways muscles / Randerath, W.J. -- Cardiac pacemaker therapy in sleep apnea / Schichtl, T., Pfeifer, M. -- Surgical treatment for obstructive sleep apnea / Boudewyns, A.N., Van de Heyning, P.H. -- Alternative therapies for obstructive sleep apnea syndrome : behavioral and pharmacological options / Smith, I.E. -- Central sleep apnea, hypoventilation syndromes, and periodic breathing disorders / Caples, S.M., Somers, V.K. -- Cardiovascular complications of sleep-related breathing disorders / Naughton, M.T., Sanner, B.M. -- Sleep-related breathing disorders in children / Amin, R.S. ... [et al.] -- Sleep-related breathing disorders in the elderly / Cooke, J.R., Ancoli-Israel, S. -- Sleep-disordered breathing in pregnancy / Sullivan, C.E., Edwards, N. Obstructive sleep apnea-hypopnea syndrome definitions of pathophysiology / De Backer, W. -- Oxidative stress--the culprit of obstructive sleep apnea syndrome / Lavie, L., Lavie, P. -- Genetics aspects of the obstructive sleep apnea/hypopnea syndrome / Riha, R.L. -- Upper airway muscles in obstructive respiratory sleep disorders / Svanborg, E. -- Obstructive sleep apnea : clinical presentation, diagnosis, and treatment / Yim, S., Jordan, A., Malhotra, A. -- Automatic positive airway pressure titration and treatment / Randerath, W.J. -- Treatment humidification in sleep-related breathing disorders / Benjafield, A.V., Richards, G.N. -- Oral appliances in the treatment of obstructive sleep apnea and snoring / Marklund, M. Sleep disorders and their classification--an overview / Lévy, P., Viot-Blanc, V., Pépin, J.-L -- Physiology of sleep and dreaming / Penzel, T., Kesper, K. -- Physiology of breathing during sleep / Schäfer, T. -- Physiology of the cardiovascular, endocrine, and renal systems during sleep / Peter, J.G., Fietze, I. -- History and questionnaires / Rühle K.-H. -- Objectifying sleepiness / Hein, H. -- Portable monitoring systems / Hein, H. -- Polysomnography / Penzel, T. -- Nasal, lung, and cardiovascular function tests / Galetke, W. -- Upper airway imaging in sleep apnea syndrome / Pinto Basto, R., Rodenstein, D.O. -- Upper airway obstruction in snoring and upper airway resistance syndrome / Kirkness, J.P. ... [et al.].
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    Diurnal molecular rhythms : unrecognized critical determinants of cardiovascular health and disease / Michael J. Sole and Tami A. Martino -- Lower brainstem mechanisms of cardiorespiratory integration / Patrice G. Guyenet -- Mechanical interactions between the respiratory and circulatory systems / Sheldon Magder -- Respiratory and cardiac activity during sleep onset / John Trinder and Christian L. Nicholas -- Physiological effects of sleep on the cardiovascular system / Richard L. Horner -- Sleep apnea and alterations in glucose metabolism / Naresh M. Punjabi -- Oxidative stress, inflammation, and vascular function in obstructive sleep apnea syndrome / John Garvey ... [et al.] -- Obesity, sleep apnea, and the cardiorespiratory effects of leptin / Kenneth R. McGaffin and Christopher P. O'Donnell -- Influence of sleep and sleep apnea on autonomic control of the cardiovascular system / Krzystof Narkiewicz -- Epidemiological evidence for an association between sleep apnea, hypertension and cardiovascular disease / Yamini S. Levitzky and Susan Redline -- Treatment of hypertension in sleep apnea / Oded Friedman and Alexander G. Logan -- Sleep apnea and cardiac arrhythmias / Richard S.T. Leung and Clodagh M. Ryan -- Obstructive sleep apnea and atherosclerosis / Geraldo Lorenzi-Filho and Luciano F. Drager -- Sleep apnea and stroke / Massimiliano M. Siccoli and Claudio L. Bassetti -- Circadian rhythm of cardiac and cerebrovascular ischemic events / Dan Sprajja and Apoor S. Gami -- Quantitative models of periodic breathing and Cheyne-Stokes respiration / Michael C.K. Khoo -- Pathophysiological interactions between sleep apnea and heart failure / Dai Yamino, John S. Floras, and T. Douglas Bradley -- Prevalence and prognostic significance of obstructive and central sleep apnea in heart failure / Paula A. Lanfranchi -- Treatment of obstructive and central sleep apnea in patients with heart failure / Matthew T. Naughton and Michael Arzt.
  • The cognitive and behavioral implications of sleep deprivation have been noted in the medical literature for many years. In addition, emerging research continues to demonstrate the contribution of sleep deprivation to some of the most common and costly health conditions today. Sleep Deprivation and Disease provides clinically relevant scientific information to help clinicians, public health professionals, and researchers recognize the ramifications of sleep deprivation across a broad spectrum of health topics. This timely reference covers sleep physiology, experimental approaches to sleep deprivation and measurement of its consequences, as well as health and operational consequences of sleep deprivation. Clinical challenges and areas of uncertainty are also presented in order to encourage future advancements in sleep medicine and help patients avoid the outcomes associated with the myriad causes of sleep deprivation.
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    Perspectives / Wynne Chen and Clete A. Kushida -- History of sleep deprivation / William C. Dement, Clete A. Kushida, and Judy Chang -- Animal models of sleep deprivation / Joan C. Hendricks -- Sleep deprivation/fragmentation paradigms. Total sleep deprivation / Chiara Cirelli and Giulio Tononi. Partial and sleep-state selective deprivation / Carol A. Landis. Sleep fragmentation / Michael H. Bonnet -- Extrinsic factors affecting sleep loss/deprivation. Environmental influences on sleep and sleep deprivation / Kenneth P. Wright, Jr. Shift work / June J. Pilcher. Medications, drugs of abuse, and alcohol / Jonathan A.E. Fleming and Clete A. Kushida. Factors affecting test performance / Tracy F. Kuo and Clete A. Kushida -- Intrinsic factors affecting sleep loss/deprivation: cognitive, physiologic, and molecular associations. Attention and memory changes / Geneviève Forest and Roger Godbout. Cortical and electroencephalographic changes / Luca A. Finelli. Physiological and neurophysiological changes / Mahesh M. Thakkar and Robert W. McCarley. Metabolic and endocrine changes / Karine Spiegel, Rachel Leproult, and Eve Van Cauter. Thermoregulatory changes / Paul J. Shaw. Biochemical changes / Birendra N. Mallick, Vibha Madan, and Mohammad Faisal. Immunologic changes / Sarosh J. Motivala and Michael Irwin. Changes in gene expression / Chiara Cirelli. Criteria for classifying genes as sleep or wake genes / Priyattam J. Shiromani ... [et al.] -- Intrinsic factors affecting sleep loss/deprivation: psychiatric associations. Mood changes / Camellia P. Clark. Antidepressant effects / Joseph C. Wu ... [et al.] Personality/psychopathologic changes / Camellia P. Clark, J. Christian Gillin, and Barbara L. Parry -- Other intrinsic factors affecting sleep loss/deprivation. Age and individual determinants of sleep loss effects / Hélène Gaudreau, Julie Carrier, and Bwanga-Mukishi Tchiteya. Homeostatic and circadian influences / Joel H. Benington.
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  • Part 1. The Normal Upper Airway -- Upper Airway Structure During Development / Seung Hoon Lee -- Functional Aspects and Upper Airway Control During Wakefulness and Sleep / Neriel Katz, Tamar Etzioni and Giora Pillar -- Lymphadenoid Tissues in the Upper Airway / Jinkwan Kim and David Gozal -- The Nasal Airway / Fuad M. Baroody -- Part 2. Sleep During Development -- Neural Mechanisms of Sleep and Circadian Rhythms / Edgar Garcia-Rill -- EEG and Sleep During Development / Raffaele Ferri, Luana Novelli and Oliviero Bruni -- Autonomic Cardiovascular Regulation During Sleep / Anna Vlahandonis, Lisa M. Walter, Stephanie R. Yiallourou and Rosemary S.C. Horne -- Arousal: Ontology, Functional Anatomy, Methodology, and Consequences / Eliot S. Katz -- Metabolic and Hormonal Regulation During Sleep / Riva Tauman -- Chemoreceptors, Breathing, and Sleep / John L. Carroll, Supriya K. Jambhekar and David F. Donnelly -- Pathophysiology of Pediatric Obstructive Sleep Apnea: Putting It All Together / Eliot S. Katz -- Part 3. Diagnostic Assessment of Sleep and Breathing in Children -- Clinical Evaluation of the Pediatric Patient / Hari P.R. Bandla -- Actigraphy / Hawley E. Montgomery-Downs and Lisa J. Meltzer -- Abbreviated/Portable Recordings / Luigi Ferini-Strambi -- Overnight Sleep Study and MSLT / Jyoti Krishna -- Upper Airway Imaging in Children with Obstructive Sleep Apnea Syndrome / Raanan Arens and Sanghun Sin -- The "Omics" Future: Genomics, Transcriptomics, and Proteomics / Sina A. Gharib -- Pediatric Sleep-Disordered Breathing: Criteria and Spectrum of Disease / Karen Spruyt -- Part 4. SDB in Children -- Apnea of Prematurity / Christian F. Poets -- Epidemiologic Aspects of Pediatric OSA Around the World / Athanasios Kaditis -- Obesity and Sleep / Edward O. Bixler, Alexandros N. Vgontzas, Marina Tsaoussoglou and Susan L. Calhoun -- Obstructive Sleep Apnea in Children with Down Syndrome / Dennis Rosen -- Children with Neuromuscular Disorders / Aviv D. Goldbart -- Sleep Problems in Children with Sickle Cell Disease / Umakanth Khatwa, Alia Bazzy-Asaad and Sanjeev V. Kothare -- Children with Craniofacial Syndromes / Wendy Estrellado-Cruz and Robert C. Beckerman -- Epilepsy, Headache, and Sleep-Disordered Breathing / Martina Vendrame and Sanjeev V. Kothare -- Sleep and Breathing in Cystic Fibrosis / Amanda J. Piper -- Asthma and Obstructive Sleep Apnea / Leila Kheirandish-Gozal -- Central Hypoventilation Syndromes / Iris A. Perez, Thomas G. Keens and Sally L. Davidson Ward -- Health-Care Utilization and Pediatric Obstructive Sleep Apnea / Ariel Tarasiuk and Haim Reuveni -- Gastroesophageal Reflux and Sleep-Disordered Breathing / Hari P.R. Bandla and Aparna R. Rao -- Part 5. Consequences of SDB in Children -- Behavioral Morbidity in Pediatric Sleep-Disordered Breathing / Elise K. Hodges, Barbara True Felt, Bruno J. Giordani and Ronald D. Chervin -- Neurocognitive Function and Learning in Children with Sleep-Disordered Breathing / Karen Spruyt -- Brain Regulatory Mechanisms Underlying Breathing: Insights for Sleep Pathology / Ronald M. Harper, Rajesh Kumar, Paul M. Macey, Jennifer A. Ogren and Mary A. Woo -- Cardiovascular Implications / Rakesh Bhattacharjee and Leila Kheirandish-Gozal -- Metabolic Consequences of Sleep Disorders / David Gozal -- Enuresis and Obstructive Sleep Apnea in Children / Oscar Sans Capdevila and Maria Eugenia Russi Delfraro -- Part 6. Treatment of SDB -- Adenotonsillectomy / Rakesh Bhattacharjee -- Corticosteroids and Leukotriene Modifiers in Pediatric SDB / Aviv D. Goldbart and Leila Kheirandish-Gozal -- CPAP Treatment in Children / Dafna Ofer and Carole L. Marcus -- Mandibular Advancement Devices / Maria Pia Villa and Silvia Miano -- Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome / Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens and Anna S. Kenny, et al.
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    Concept of sleep medicine and of neurosomnology / Antonio Culebras -- Disorders of development and maturation of sleep / Stephen H. Sheldon -- Sleep disorders associated with mental retardation / Michael J. Rack -- Insomnia in neurology / Federica Provini, Carolina Lombardi, and Elio Lugaresi -- Delayed sleep phase disorder and other circadian rhythm sleep disorders / Baruch El-Ad -- Narcolepsy / Claudio L. Bassetti -- Secondary narcolepsy / Thomas E. Scammell -- Hypocretin, hypothalamic system / Christian R. Baumann and Claudio L. Bassetti -- Idiopathic hypersomnia and recurrent hypersomnia / Douglas B. Kirsch and Ronald D. Chervin -- Motor disorders of sleep: periodic, aperiodic, and rhythmic motor disorders / Roberto Vetrugno and Pasquale Montagna -- Restless legs syndrome / Renata Egatz, Belen Cabrero, and Diego Garcia-Borreguero -- Periodic leg movements of sleep / Diego Garcia-Borreguero, Oscar Larrosa, and Renata Egatz -- Sleep in Parkinson's disease / Robert L. Rodnitzky -- Epilepsy and sleep / Bradley V. Vaughn and O'Neill F. D'Cruz -- Somnambulism, somniloquy, and sleep terrors / Rosalia Silvestri -- Rapid eye movement sleep behavior disorder / Mark W. Mahowald and Carlos H. Schenck -- Obstructive and nonobstructive sleep apnea: the neurological perspective / Gulcin Benbir and Christian Guilleminault -- Sleep apnea and stroke / Antonio Culebras -- Sleep disturbances in dementia and other neurodegenerative -- disorders / Alon Y. Avidan -- Autonomic dysfunctions in sleep disorders / Pietro Cortelli and Carolina Lombardi -- Headache disorders and sleep / Antonio Culebras -- Sleep in traumatic brain injury and other acquired central nervous system conditions / Mark W. Mahowald -- Sleep disorders associated with multiple sclerosis / Antonio Culebras -- Sleep disorders and neuromuscular disorders / Antonio Culebras --Stimulant-dependent and hypnotic-dependent sleep disorders / Harold R. Smith.
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  • Sleep physiology -- Extent and health consequences of chronic sleep loss and sleep disorders -- Functional and economic impact of sleep loss and sleep-related disorders -- Improving awareness, diagnosis, and treatment of sleep disorders -- Ensuring adequate diagnosis and treatment : access, capacity, and technology development -- Opportunities to improve career development in somnology -- Bolstering somnology and sleep disorders research programs -- Building sleep programs in academic health centers.
  • In Sleep Disorders in Women: A Guide to Practical Management, 2nd Edition, a multidisciplinary panel of eminent researchers and practicing clinicians comprehensively updates the multifaceted aspects of sleep disorders in women at different stages of life, illuminating the unique impact that each reproductive and endocrine stage has on both normal sleep and sleep disorders. This title not only introduces primary care physicians and health care providers to the discipline of sleep disorders in women, it also will appeal to a broader set of specialists as it summarizes the latest, cutting-edge research and presents it in a succinct and clinically relevant manner. The goal of this book is to help physicians recognize the symptom patterns of sleep disorders in their female patients, guide them in diagnosing and treating these patients in a timely fashion, and help in the elimination of gender bias in sleep medicine research and care. An invaluable addition to the literature, Sleep Disorders in Women: A Guide to Practical Management, 2nd Edition again fills an important niche by being an accessible, comprehensive, multidisciplinary review on sleep disorders in women.
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    Introduction / William C. Dement -- An overview of normal sleep / Sudhansu Chokroverty -- Sleep deprivation and sleepiness / Sudhansu Chokroverty -- Neurobiology of rapid eye movement and non-rapid eye movement sleep / Robert W. McCarley -- Neurophysiologic mechanisms of slow-wave (non-rapid eye movement) sleep / Mircea Steriade -- Neurotransmitters, neurochemistry, and the clinical pharmacology of sleep / Max Hirshkowitz, Mary Wilcox Rose and Amir Sharafkhaneh -- Physiologic changes in sleep / Sudhansu Chokroverty -- Circadian timing and sleep-wake regulation / Robert Y. Moore -- Sleep and memory consolidation / Matthew P. Walker and Robert Stickgold -- Dreaming in sleep-disordered patients / Rosalind Cartwright -- Polysomnographic technique : an overview / Sharon A. Keenan -- Electroencephalography, electromyography, and electro-oculography : general principles and basic technology / Thaddeus S. Walczak and Sudhansu Chokroverty -- Electrocardiographic technology of cardiac arrhythmias / Daniel M. Shindler and John B. Kostis -- Evaluation and monitoring of respiratory function / Reena Meara and Kingman P. Strohl -- Neuroimaging in sleep and sleep disorders / Martin Desseilles ... [et al.] -- Measurement of sleepiness and alertness : multiple sleep latency test / Thomas Roth and Timothy A. Roehrs -- The maintenance of wakefulness test / Karl Doghramji -- Clinical polysomnography and the evolution of recording and scoring technique / Max Hirshkowitz and Amir Sharafkhaneh -- Approach to the patient with sleep complaints / Sudhansu Chokroverty -- Classification of sleep disorders / Michael J. Thorpy -- Epidemiology of sleep disorders / Maurice Moyses Ohayon and Christian Guilleminault -- Human and animal genetics of sleep and sleep disorders / Stéphanie Maret, Yves Dauvilliers, and Mehdi Tafti -- Nutrition and sleep / Markku Partinen -- Obstructive sleep apnea syndrome / Christian Guilleminault and Michael Zupancic -- Positive airway pressure in the treatment of sleep apnea-hypopnea / Mark H. Sanders ... [et al.] -- Nature and treatment of insomnia / Charles M. Morin and Ruth M. Benca -- Narcolepsy / Christian Guilleminault and Vivien C. Abad -- Motor functions and dysfunctions of sleep / Wayne A. Hening ... [et al.] -- Sleep, breathing, and neurologic disorders / Sudhansu Chokroverty and Pasquale Montagna -- Sleep and epilepsy / Sudhansu Chokroverty and Pasquale Montagna -- Dreaming in neurologic disorders / Mark Solms and Susan Malcolm-Smith -- Sleep in psychiatric disorders / Peter L. Franzen and Daniel J. Buysse -- Sleep disturbances in general medical disorders / Sudhansu Chokroverty -- Circadian rhythm disorders / Mark W. Mahowald and Milton G. Ettinger -- Parasomnias / Jacques Montplaisir ... [et al.] -- Sleep disorders in the elderly / Sudhansu Chokroverty -- Sleep disorders of childhood / Richard Ferber -- Evolution of sleep from birth through adolescence, and sleep-disordered breathing in children / Timothy F. Hoban -- Women's sleep / Helen S. Driver and Eileen P. Sloan -- Sleep-related violence : forensic medicine issues / Mark W. Mahowald and Carlos H. Schenck.
  • Sleep disorders. Part I-II pt. 1-2, 2011.
    pt. 2, 2011 ScienceDirect
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  • Circadian Clock Genes and the Regulation of Sleep / Thomas Curie and Paul Franken -- Clock Genes and Energy Metabolism / Hee-Kyung Hong, Wenyu Huang, Kathryn Moynihan Ramsey, Biliana Marcheva and Joseph Bass -- Neural Circuitry Responsible for Sleep and Wakefulness / Roda Rani Konadhode, Dheeraj Pelluru and Priyattam J. Shiromani -- Feeding as a Reward Mechanism / Ralph J. DiLeone, Nandakumar S. Narayanan and Douglas J. Guarnieri -- Plasticity of Brain Feeding Circuits in Response to Food / Tamas Horvath -- The Neurogenetics of Energy Balance / Martin G. Myers Jr. -- Short Sleep and Obesity Risk in Children / Chantelle N. Hart, Elizabeth S. Kuhl and Elissa Jelalian -- Circadian Misalignment and Sleep Disruption in Shift Work: Implications for Fatigue and Risk of Weight Gain and Obesity / Rachel R. Markwald and Kenneth P. Wright Jr. -- Sleep Apnea and Obesity / Vidya Krishnan and Sanjay R. Patel -- The Connection Between Sleep Loss, Obesity, and Type 2 Diabetes / Silvana Pannain, Guglielmo Beccuti and Eve Van Cauter -- Sleep Disturbances: Impact on Risk and Severity of Diabetes / Kelly A. Holes-Lewis -- Insufficient Sleep and Cardiovascular Disease / Susan Redline -- Clinical Guidelines for the Evaluation of Adults with Obstructive Sleep Apnea / Lawrence J. Epstein -- Pharmacological Treatment of Obesity / Dhiraj G. Kabra, Uma D. Kabra, Matthias H. Tschöp and Susanna Hofmann -- Bariatric Surgery for Treatment of Obesity / Mark J. Perna, Thomas Karl Byrne and Chitharanja C. Pullattrana.
  • A new addition to the Neurology in Practice series, Sleep Medicine in Neurology is a practical guide for neurologists diagnosing and managing sleep disorders in their patients. As a part of the series, various feature boxes are highlighted throughout. ""Tips and Tricks"" give suggestions on how to improve outcomes through practical technique or patient questioning. In addition, ""Caution"" warning boxes supply helpful advice on how to avoid problems and 'Science Revisited' boxes offer quick reminders of the basic science principles necessary for understanding the presented concepts.
  • Behavioral and electrophysiological correlates of sleep and sleep homeostasis -- Genetic dissection of sleep homeostasis -- Sleep deprivation and gene expression -- Sleep and synaptic homeostasis -- Sleep and synaptic plasticity in the developing and adult brain -- Sleep and adult neurogenesis: implications for cognition and mood -- Animal studies on the role of sleep in memory: from behavioral performance to molecular mechanisms -- A bird's eye view of sleep-dependent memory consolidation -- Neuroimaging studies of sleep and memory in humans -- The role of sleep in human declarative memory consolidation -- Sleep-dependent memory consolidation in healthy aging and mild cognitive impairment -- Adenosine, caffeine, and performance: from cognitive neuroscience of sleep to sleep pharmacogenetics -- Optogenetic control of hypocretin (orexin) neurons and arousal circuits -- Stress, arousal, and sleep -- Sleep and emotional functions -- Sleep and plasticity in schizophrenia -- Chronically restricted or disrupted sleep as a casula factor in the development of depression -- Sleep deprivation therapy for depression -- Pharmacological treatment of sleep disorders and its relationship with neuroplasticity -- Index.
  • "Human Impact Assessment (HuIA) is a relatively new concept describing an integrated process that encompasses both Health Impact Assessment and Social Impact Assessment and is used to anticipate the effects of programs, projects and decisions on human health and welfare. Sleep occupies approximately one-third of our lives, but its human impact remains largely unrecognized. The prevalence of excessive sleepiness is recognized to be increasing in industrialized societies. Sleepiness and fatigue have high costs in terms of both lives lost and socioeconomic impact. Sleepiness and Human Impact Assessment provides a comprehensive exploration of many different facets of sleepiness in our 24-hour society from the new HuIA point of view. Among the covered issues are the physiology and pathophysiology of sleep, its relationship to daytime alertness, fatigue and drugs, the relevance of sleep-related fatigue in various occupational settings and public safety. This book will be of assistance to physicians, occupational health professionals, ergonomists, researchers and decision-makers as they strive to understand the full significance of sleepiness and to create a culture of accountability in everyday life without sleep-related risks."--Publisher's website.
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  • V. 1: -- Sect. I: Biology of the gastrointestinal tract -- Sect. II: Nutrition in gastroenterology -- Sect. III: Symptoms, signs, and biopsychosocial issues -- Sect. IV: Topics involving multiple organs -- Sect. V: Esophagus -- Sect. VI: Stomach and duodenum -- Sect. VII: Pancreas -- Sect. VIII: Biliary tract -- V. 2: -- Sect. IX: Liver -- Sect. X: Small and large intestine -- Sect. XI: Additional treatments for patients with gastrointestinal and liver disease.
  • In this book the author describes in detail the history, construction, and examination potential of the slit lamp. In particular, however, he presents a new approach videography that allows the ophthalmologist to document all (!) eye diseases with the slit lamp and a video camera in a practicable, rapid, and affordable manner. The necessary methods, techniques, and equipment, including converging, diverging, and contact lenses, are clearly explained in the text and four didactic videos. The 20 most important videographic settings are described, and recipes for their use are presented, along with diagnostic tips. The accompanying collection of clinical images represents the world's first ever general atlas of ophthalmology from the perspective of the slit lamp. The author has already demonstrated proof of the value of ophthalmological videography in his own practice. It is his hope that this introductory book, with its many images never previously produced with a slit lamp, will stimulate others to exploit the approach's potential.
  • Slow oscillations in perspective and in detail -- Slow brain oscillations of sleep, resting, state, and vigilance -- Electrophysiological correlates of sleep homeostasis in freely behaving rats -- Involvement of cytokines in slow wave sleep -- Sleep and resting state EEG-profile as heritable endophenotype and during development -- Genetic determination of sleep EEG profiles in healthy humans -- Developmental aspects of sleep slow waves: linking sleep, brain maturation and behavior -- Phasic events during slow oscillations -- Phasic modulation of cortical high-frequency oscillations by pedunculopontine neurons -- Slow oscillations orchestrating fast oscillations and memory consolidation -- Spontaneous neural activity during human non-rapid eye movement sleep -- Thalamocortical and cortico-hippocampal network interactions during slow sleep oscillations -- Neuronal plasticity and thalamocortical sleep and waking oscillations -- Infraslow (<0.1 Hz) oscillations in thalamic relay nuclei: basic mechanisms and significance to health and diseaes states -- Hippocampal-cortical interactions and the dynamics of memory trace reactivation -- Cortica synchronization and travelling of slow oscillations -- Long-range correlation of the membrane potential in neocortical neurons during slow oscillation -- Temporal dynamics of cortical sources underlying spontaneous and peripherally evoked slow waves -- Functional beliefs of slow oscillations during sleep -- Sleep and developmental plasticity: not just for kids -- Evoked electrical and cerebral vascular responses during sleep and following sleep deprivation -- Reduction of nocturnal slow-wave activity affects daytime vigilance lapses and memory encoding but not reaction time or implicit learning -- Infraslow oscillations in resting state network activity during sleep and wakefulness -- Spectral characteristics of resting state networks -- Modulation of the brain's functional network architecture in the transition from wake to sleep -- Spontaneous fMRI activity during resting wakefulness and sleep -- Infraslow oscillations, consciousness and performance -- Hypnotic modulation of resting state mMRI default mode and extrinsic network connectivity -- Multimodal neuroimaging in patients with disorders of consciousness showing functional hemispherectomy -- Roles of multiscale brain activity fluctuations in shaping the variability and dynamics of psychophysical performance.
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    v. 1. Clinical, epidemiological, genetic, and pathological aspects of the spongiform encephalopathies -- v. 2. Pathogenesis, immunology, virology, and molecular biology of the spongiform encephalopathies.
  • Pt. I. Role of Small Animal Imaging -- 1. Noninvasive Imaging for Supporting Basic Research / Pat Zanzonico -- 2. Non-Invasive Imaging in the Pharmaceutical Industry / John C. Waterton -- 3. How to Set Up a Small Animal Imaging Unit / David Stout -- 4. Noninvasive Small Rodent Imaging: Significance for the 3R Principles / Peter Maier -- Pt. II. Study Planning and Animal Preparation -- 5. Institutional Preconditions for Small Animal Imaging / Rene H. Tolba -- 6. Statistical Considerations for Animal Imaging Studies / Hannes-Friedrich Ulbrich -- 7. Animal Anesthesia and Monitoring / Rene H. Tolba -- 8. Drug Administration / Peter Hauff -- Pt. III. Imaging Modalities and Probes -- 9. How to Choose the Right Imaging Modality / Peter Hauff -- 10. X-Ray and X-Ray-CT / Marek Karolczak -- 11. CT Contrast Agents / Hubertus Pietsch -- 12. Small Animal Magnetic Resonance Imaging: Basic Principles, Instrumentation and Practical Issue / Peter Jakob -- 13. MR Contrast Agents / Silvio Aime -- 14. MR Spectroscopy / Markus Becker -- 15. Ultrasound / Catherine Theodoropoulos -- 16. Ultrasound Contrast Agents / Michel Schneider -- 17. PET and SPECT / Sibylle I. Ziegler -- 18. Radiotracer I: Standard Tracer / Uwe Haberkorn -- 19. Radiotracer II: Peptide-Based Radiopharmaceuticals / Clemens Decristoforo -- 20.Optical Imaging / Vasilis Ntziachristos -- 21. Optical Probes / Kai Licha -- 22. Multi-modal Imaging and Image Fusion / Vesna Sossi -- Pt. IV. Ex Vivo Validation Methods -- 23. Ex Vivo and In Vitro Cross Calibration Methods / Thierry Delzescaux -- 24. In Vitro Methods for In Vivo Quantitation of PET and SPECT Imaging Probes: Autoradiography and Gamma Counting / David Stout -- pt. V Data Postprocessing -- 25. Qualitative and Quantitative Data Analysis / Volkmar Schulz -- 26. Guidelines for Nuclear Image Analysis / Bernd J. Pichler -- 27.Kinetic Modelling / Jorg van den Hoff -- 28.Data Documentation Systems / Wolfhard Semmler -- Pt. VI. Special Applications -- 29. Imaging in Developmental Biology / Michal Neeman -- 30. Imaging in Gynecology Research / Michael D. Menger -- 31. Imaging in Cardiovascular Research / Sven Hermann -- 32. Imaging in Neurology Research I: Neurooncology / Andreas H. Jacobs -- 33. Imaging in Neurology Research II: PET Imaging of CNS Disorders / Alexander Drzezga -- 34. Imaging in Neurology Research III: Focus on Imaging Neurotransmitter / Wynne K. Schiffer -- 35. Imaging in Oncology Research / Fabian Kiessling -- 36. Imaging in Immunology Research / Owen N. Witte.
  • Like many fields of science, the future of medicine is frequently predicted by the science fiction writers of today, very much as many of today's medical advances were presaged by science fiction stories of the past. In this book, physician and science fiction author Brad Aiken conveys his own speculations about our medical future through nine highly entertaining and thought-provoking short stories. Touching upon a great variety of themes, including but not limited to telemedicine and remote surgery, vaccination strategies against unknown deathly pathogens, nanomedicine to cure diseases and retard ageing, bionics, cloning and euthanasia, we get a glimpse of what might be awaiting humanity. Yet, in these stories it is always the protagonists, humans after all, who remain at the center stage, not the new technologies. This provides the fictional material with a unique blend of science fiction and social fantasy. It also warns us to be wary of the pitfalls of too much reliance on dehumanizing technology and to make sure it remains our helper, not our master. Last but not least, an extensive scientific essay investigates the interplay between science fiction and both past and current advances in medical sciences and technology, making the link to the fictional material in the book as well as to the relevant scientific literature.
  • Children born small for gestational age : definitions and etiology / Wollmann, H.A. -- Diagnosis and management of in utero growth failure / Odibo, A.O.; Sadovsky, Y. -- Fetal growth restriction and the developmental origins of adult disease hypothesis : experimental studies and biological consequences / Krechowec, S.O.; Thompson, N.M.; Breier, B.H. -- Molecular genetic disorders of fetal growth / Chernausek, S.D. -- Birth weight and later risk of type 2 diabetes / Harder, T. ... [et al.] -- Low birth weight and optimal fetal development : a global perspective / Franko, K.L. ... [et. al.] -- Insulin-like growth factor/growth hormone axis in intrauterine growth and its role in intrauterine growth retardation / Kiess, W. ... [et al.] -- Clinical management of small-for-gestational-age babies / Knüpfer, M. -- Management of short stature in small-for-gestational-age children / Dahlgren, J. -- Puberty and adrenarche in small-for-gestational-age children / Hokken-Koelega, A.C.S. -- Neurological and intellectual consequences of being born small for gestational age / Tuvemo, T.; Lundgren, E.M. -- Low birth weight in developing countries / Qadir, M.; Bhutta, Z.A.
  • pt. B ScienceDirect
    pt. C ScienceDirect
    pt. A. Ras family -- pt. B. Rho family -- pt. C. Proteins involved in transport.
  • Small GTPases in disease. Part A-B pt. A-B, 2008.
    pt. B ScienceDirect
  • The Expanding World of Small Molecule Microarrays / Mahesh Uttamchandani and Shao Q. Yao -- Construction of Photo-Cross-Linked Microarrays of Small Molecules / Naoki Kanoh -- Small Molecule Microarray : Functional-Group Specific Immobilization of Small Molecules / Hyang Yeon Lee and Seung Bum Park -- Detecting Protein-Small Molecule Interactions Using Fluorous Small Molecule Microarrays / Arturo J. Vegas and Angela N. Koehler -- A Method for Small Molecule Microarray-Based Screening for the Rapid Discovery of Affinity-Based Probes / Haibin Shi, Mahesh Uttamchandani, and Shao Q. Yao -- Nanodroplet Chemical Microarrays and Label-Free Assays / Dhaval Gosalia and Scott L. Diamond -- Nanodroplet Microarrays for High-Throughput Enzyme Screening / Kang L.D. Aw, Shao Q. Yao, and Mahesh Uttamchandani. The Application of the Chemical Array for Biological Study / Isao Miyazaki, Siro Simizu, and Hiroyuki Osada -- Peptide Arrays with a Chip / Alexander Nesterov, Edgar Dörsam, Yun-Chien Cheng, Christopher Schirwitz, Frieder Märkle, Felix Löffler, Kai König, Volker Stadler, Ralf Bischoff, and Frank Breitling -- In situ Chemical Modification of Peptide Microarrays : Characterization by Desorption/Ionization on Silicon Nanowires / Gaëlle Piret, Herv Drobecq, Carine Rouanet, Karim Chemlal, Anne-Sophie Debrie, Jean-Michel Hougardy, Françoise Mascart, Camille Locht, and Oleg Melnyk -- Peptide Microarrays on Coated Silicon Slides for Highly Sensitive Antibody Detection / Marina Cretich, Francesco Damin, Renato Longhi, Cecilia Gotti, Clelia Galati, Lucio Renna, and Marcella Chiari. Antibody Signatures Defined by High-Content Peptide Microarray Analysis / Antonia Masch, Johannes Zerweck, Ulf Reimer, Holger Wenschuh, and Mike Schutkowski -- High Density Peptide Microarrays for Proteome-Wide Fingerprinting of Kinase Activities in Cell Lysates / Alexandra Thiele, Matthias Weiwad, Johannes Zerweck, Gunter Fischer, and Mike Schutkowski -- A Peptide Microarray for Detecting Protein Kinase Activity in Cell Lysates / Xiaoming Han and Yoshiki Katayama -- Chemical Microarrays Constructed by Selective Attachment of Hydrazide-Conjugated Substances to Epoxide Surfaces and Their Applications / Sungjin Park, Myung-Ryul Lee, and Injae Shin -- A Microarray-Based Method to Perform Nucleic Acid Selections / Olga Aminova and Matthew D. Disney.
  • Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the progress being made will result in significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book, written by acknowledged experts, discusses in detail the most recent developments in targeted cancer therapy using small molecules. A wide range of small molecules is covered, including, in addition to tyrosine kinase inhibitors, mTOR, proteasome, and multikinase inhibitors, among others. For each molecule, aspects such as chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.
  • Introduction -- Inheritance of small supernumerary marker chromosomes -- Formation of small supernumerary marker chromosomes -- Small supernumerary marker chromosomes in genetic diagnostics and counseling -- Small supernumerary marker chromosomes known to be correlated with specific syndromes -- Centric small supernumerary marker chromosomes -- Neocentric small supernumerary marker chromosomes by chromosome -- Multiple small supernumerary marker chromosomes -- Small supernumerary marker chromosomes additionally to other chromosomal rearrangements -- Complex small supernumerary marker chromosomes -- Small supernumerary marker chromosomes and tumors -- Appendix: Patient organizations in connection with small supernumerary marker chromosomes -- Glossary.
  • Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions / M.J. Adler, A.G. Jamieson and Andrew D. Hamilton -- Small-molecule inhibitors of IL-2/IL-2R : Lessons learned and applied / C.G. Wilson and M.R. Arkin -- Small molecule inhibitors of the human papillomavirus E1-E2 interaction / P.W. White, Anne-Marie Faucher and Nathalie Goudreau -- Design of small-molecule Smac mimetics as IAP antagonists / Shaomeng Wang -- Small-molecule inhibitors reveal a new function for Bcl-2 as a proangiogenic signaling molecule / Benjamin D. Zeitlin and Jacques E. Nör -- Small-molecule modulators of c-Myc/Max and Max/Max interactions / Thorsten Berg -- Small-molecule inhibitors of the p53-MDM2 interaction / Binh T. Vu and Lyubomir Vassilev.
  • "Scientifically known as Variola major, the deadliest form of smallpox has plagued mankind since 'time immemorial.' This text chronicles the worldwide effects of the killer disease, with particular emphasis on the 19th and 20th centuries, including the devastations of the "speckled disease" during great armed conflicts"--Provided by publisher.
  • "Planning, conducting, and publishing the results of your clinical research can be a long and arduous journey. The SMART Approach to Spine Clinical Research presents and explains the many interrelated components essential to spine clinical research in an easily accessible way, guiding you step-by-step through the principles and methods of planning and evaluating clinical research."--Cover.
  • The team physician and general care of the athlete / Jennifer Hart -- Medical issues in the athlete / Jennifer Hart -- Shoulder / S. Raymond Golish ... [et al.] -- Elbow / Luke S. Oh -- Wrist & hand / Jack Ingari -- Knee / Mark D. Miller -- Hip, pelvis and thigh / Brian D. Busconi & Robert M. Masella -- Ankle and foot / Anish R. Kadakia & David Joos -- Head and spine / Sanjitpal S. Gill & Katey A. Dorweiler -- Sports medicine research and statistics / Joseph M. Hart.
  • Smith & Tanagho's General urology 2013 (18th ed.)
  • A practical guide for anaesthetists and other health care professionals involved in the perioperative period. This sixth edition has been thoroughly updated and reorganised to reflect current anaesthetic practice and the basic sciences that directly underpin it. The inclusion of several new chapters continues to ensure complete coverage of key and evolving areas and new, experienced authors also add a fresh perspective to this edition.
  • 2011 ClinicalKey
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  • This medical reference book provides you with complete and authoritative, yet accessible guidance to help accurately diagnose these human disorders, establish prognoses, and provide appropriate management and genetic counseling. Recognize the visual signs of each environmental and genetic abnormality by consulting more than 1,500 full-color photographs and illustrations, many from the personal collections of Drs. Smith and Jones. Find all the answers you need about normal and abnormal morphogenesis, minor anomalies and their relevance, clinical approaches to specific diagnoses, and normal standards of measurement for the entire spectrum of human malformation syndromes. Efficiently identify genetic disorders in your patients with the inclusion of nearly 20 recently recognized entities/syndromes, as well as new chapters on Microdeletions and Microduplication Syndromes.
  • Smoking and Lung Inflammation is the first book directly related to chronic lung inflammation of its kind in several respects. First, the it focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. Second, it is unique with respect to scope of the discussion of the unusual characteristics of the immune response which occurs in these patients. Third, it includes knowledge being gained from translational research conducted through clinical trials at several Medical Schools in the United States. Not only is this research providing information about novel drugs and therapies, but it is also advancing our understanding of the genetics of these diseases. This work will illuminate the molecular basis for these diseases, and hopefully will permit us to individualize the therapies for these diseases.
  • From nicotine dependence to genetic determinants of smoking -- State of the art of smoking habits in the world -- Smoking-related diseases epidemiology -- Smoking-related cancer epidemiology -- Classical determinants of smoking initiation -- Smoking prevention in the communities -- Smoking prevention through mass media campaigns -- How to tackle smoking at the population level -- Smoking among health professionals -- Basic principles of smoking cessation techniques -- Smoking cessation among different settings -- Media and smoking cessation -- Ethical aspects of tobacco smoking -- Economic issues related to tobacco smoking -- Appendix.
  • Viscosity -- Law of Poiseuille -- Bernoulli's equation -- Turbulence -- Arterial stenosis -- Resistance -- Inertance -- Oscillatory flow theory -- Law of Laplace -- Elasticity -- Compliance -- Cardiac muscle mechanics -- The pressure-volume relation -- The pump function graph -- Cardiac work, energy and power -- Cardiac oxygen consumption and hemodynamics -- Cardiac power and ventriculo-arterial coupling -- The coronary circulation -- Assessing ventricular function -- Wave travel and velocity -- Wave travel and reflection -- Waveform analysis -- Arterial input impedance -- The arterial windkessel -- Distributed models and tube models -- Transfer of pressure -- Mechanotransduction and vascular remodeling -- Blood flow and arterial disease -- Determinants of pressure and flow -- Comparative physiology -- Times and sines: Fourier analysis -- Basic hemodynamic elements -- Vessel segment -- Wave speed and characteristic impedance -- Basic aspects -- Books for reference -- Symbols -- Units and conversion factors.
  • Sobotta - Atlas of Human Anatomy: the exam atlas for understanding, learning, and training anatomy The English-language Sobotta Atlas with English nomenclature is specifically adapted to the needs of preclinical medical students. Right from the start, the book and the Internet content concentrate on exam-relevant knowledge. The new study concept simplifies learning-understanding-training: Descriptive legends help the student identify the most important features in the figures. Clinical examples present anatomical details in a wider context. All illustrations have been optimized, and the lettering reduced to a minimum. An additional booklet containing 100 tables on muscles and nerves supports systematic study. Volume 1 "General Anatomy and Musculoskeletal System" includes the following topics: General Anatomy Trunk Upper Extremity Lower Extremity.
  • Sobotta - Atlas of Human Anatomy: the exam atlas for understanding, learning, and training anatomy The English-language Sobotta Atlas with English nomenclature is specifically adapted to the needs of preclinical medical students. Right from the start, the book concentrate on exam-relevant knowledge. The new study concept simplifies learning-understanding-training: Descriptive legends help the student identify the most important features in the figures. Clinical examples present anatomical details in a wider context. All illustrations have been optimized, and the lettering reduced to a minimum. An additional booklet containing 100 tables on muscles and nerves supports systematic study Volume 2 "Internal Organs" includes the following topics: Viscera of the Thorax, Viscera of the Abdomen Pelvis, and Retroperitoneal Space.
  • Sobotta - Atlas of Human Anatomy: the exam atlas for understanding, learning, and training anatomy The English-language Sobotta Atlas with English nomenclature is specifically adapted to the needs of preclinical medical students. Right from the start, the book and the Internet content concentrate on exam-relevant knowledge. The new study concept simplifies learning-understanding-training: Descriptive legends help the student identify the most important features in the figures. Clinical examples present anatomical details in a wider context. All illustrations have been optimized, and the lettering reduced to a minimum. Volume 3 "Head, Neck and Neuroanatomy" includes the following topics: HeadEyeEarNeckBrain and Spinal Cord.
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    v. 1. The household survey in Indianapolis -- v. 2. The intensive study : purpose, scope, methods, and partial results.
  • This volume brings together research into diverse aspects of social anxiety and its clinical form, social phobia, in adolescents. Development of the condition, clinical manifestations, and evidence-based prevention and treatment strategies are all addressed, with emphasis on ways in which adolescent development and the broader family and peer context are reflected in the manifestation and treatment of symptoms. The first part of the book reviews epidemiological, neurobiological, and sociopsychological research on vulnerability factors that aim to clarify why both social anxiety and phobia intensify in adolescence. The second part focuses on the phenomenology of social anxiety and phobia in different developmental contexts and provides the reader with a review of developmentally-appropriate evidence-based assessment methods. For example, this section includes chapters on social anxiety in the school environment and in romantic relationships, social phobia in the clinical setting. The third section reviews the psychosocial prevention and treatment options for adolescent social anxiety as well as the psychopharmacological treatment of social phobia. Social Anxiety and Phobia in Adolescents will be informative and interesting for all child and adolescent psychiatrists, clinical psychologists, and psychotherapists as well as for school psychologists and counsellors.
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    Based on a lifetime of pioneering research, preeminent naturalist Edward O. Wilson gives us a new history of human evolution, presented in an elegant and provocative narrative that promises to have reverberations in fields as diverse as anthropology and social psychology, neuroscience and 21st-century intellectual and religious history. Wilson begins by addressing three "fundamental questions" of religion and philosophy that have fascinated thinkers for centuries: Where did we come from? What are we? Where are we going? Writing that "the origin of modern humanity was a stroke of luck, good for our species for a while, bad for most of the rest of life forever," Wilson traces the rise of Homo sapiens from its infancy, drawing on his remarkable knowledge of biology and social behavior to present us with the clearest explanation ever produced as to the origin of the human condition. Wilson also reveals how "group selection" can be the only model for explaining man's origins and domination, and warns that it has now accelerated--through unregulated and untrammeled growth--to such a point that the planet as we know it is being threatened.--From publisher description. From the most celebrated heir to Darwin comes a groundbreaking book on evolution, the summa work of Edward O. Wilson's legendary career.
  • "The thirteen case studies presented in this publication describe experiences with implementing public health programs that intend to address social determinants and to have a great impact on health equity. They also document the real-life challenges in implementing such programs, including the challenges in scaling up, managing policy changes, managing intersectoral processes, adjusting design and ensuring sustainability"--Publisher's description.
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    "Serious disparities continue to exist especially with regard to African-American men who continue to suffer disproportionately from poor health when compared to other racial, ethnic, and gender groups in the United States. This book covers the most important issues relating to social determinants of health and also offers viable strategies for reducing health disparities." --Excerpts from publisher description.
  • Chapter 1. Introduction / Jonathan Wells, Simon Strickland, and Kevin Laland -- Chapter 2. An Introduction to evolutionary models of human social behavior / Kevin Laland and Gillian Brown -- 3. How niche construction contributes to human gene-culture coevolution / John Odling-Smee -- Chapter 4. State and value : a perspective from behavioral ecology / John M. McNamara and Alasdair I. Houston -- Chapter 5. An Agnostic view of memes / Robert Aunger -- Chapter 6. Biological ends and human social information transmission / Jonathan Wells and Simon Strickland -- Chapter 7. The Significance of socially transmitted information for nutrition and health in the great ape Clade / Andrew Whiten -- Chapter 8. Language : costs and benefits of a specialized system for social information transmission / Daniel Nettle -- Chapter 9. The Evolution of social information transmission in Homo / Steven Mithen -- Chapter 10. From cultural history to cultural evolution : an archaeological perspective on social information transmission / Stephen Shennan -- Chapter 11. The Uptake of modern contraception in a Gambian community : the diffusion of an innovation over 25 years / Ruth Mace, Nadine Allal, Rebecca Sear, and Andrew Prentice -- Chapter 12. Sex without birth or death : a comparison of two international humanitarian movements / John Cleland and Susan Watkins -- Chapter 13. Smoking and the new health education in Britain, 1950s-1970s / Virginia Berridge and Kelly Loughlin -- Chapter 14. The Demographic and health impact of the one child family policy / Therese Hesketh -- Chapter 14. Social trends and psychopathology / Roland Littlewood -- Chapter 16. Epilogue : memory, tradition, and teleology / Simon Strickland.
  • This report sets out to illuminate the different ways people seek health information as well as how people use online social tools to share knowledge with loved ones, fellow patients, and caregivers.
  • Social media has been clearly changing the way medicine is practiced and healthcare is delivered. Medical professionals must be able to meet the special needs of technology-aware patients and use digital technologies in their work and communications properly. Each physician should find the tools that will assist them in their workflow, and patients need to be educated how to use the internet. It is the responsibility of medical professionals to contribute to this process. The constantly evolving digital world must be used in the practice of medicine to improve the care of patients. However, the only way to do so effectively is via evidence-based, meaningful and strategic use. Social Media in Clinical Practice provides practical guidance in this mission and is thus essential reading for all medical personal looking into approaching this for the first time.
  • Measures national progress in delivering social and environmental value to citizens. Includes statistical rankings by country in various areas, including health and wellbeing. It is designed as a complement to GDP and other economic indicators to provide a more holistic understanding of countries' overall performance.
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    What is social software? -- Blogs -- Blogs in libraries : practical applications -- RSS -- Wikis -- Online communities -- Social networking -- Social bookmarking and collaborative filtering -- Tools for synchronous online reference -- The mobile revolution -- Podcasting -- Screencasting and vodcasting -- Gaming -- What will work @ your library -- Keeping up : a primer -- Future trends in social software.
  • Chapter 1: Introduction to socio-ecological dimensions of infectious diseases and health in Southeast Asia. -- Part 1: Infectious Diseases and Societies -- Chapter 2: Climate, environment and epidemic febrile diseases: A view from Chinese medicine -- Chapter 3: Long life of people living with HIV/AIDS and the practice of medical power -- Chapter 4: Socio-environmental global changes and infectious diseases: Interdisciplinary approach applied to tourism studies -- Part 2: Socio-Ecosystems and Health -- Chapter 5: Heavy metals contamination in the ecosystem of Mae Tang reservoir in Northern Thailand -- Chapter 6: Water and health: What is the risk and visible burden of the exposure to environmental contaminations? Insights from a questionnaire-based survey in Northern Thailand -- Chapter 7: Melioidosis in Laos -- Part 3: Global Changes, Land Use Changes and Vector-Borne Diseases -- Chapter 8: Adaptation of mosquito vectors to salinity and its impact on mosquito-borne disease transmission in the South and Southeast Asian tropics -- Chapter 9: The malaria landscape: Mosquitoes, transmission, landscape, insecticide resistance and integrated control in Thailand -- Chapter 10: Rubber plantations as a mosquito box amplification in South and South-East Asia -- Part 4: Monitoring and Data Acquisition -- Chapter 11: Rescuing public health data -- Chapter 12: The new science of metagenomics and the challenges of its use in both developed and developing countries -- Chapter 13: Barcoding, biobanking, e banking: From ecological to ethical and legal aspects. Insights from the PathodivSEA project -- Part 5: Managing Health Risks -- Chapter 14: Methods for prioritization of diseases: Case study of zoonoses in South-East Asia -- Chapter 15: Managing global risks: Vietnamese poultry farmers and avian flu -- Chapter 16: The OIE Strategy to address threats at the interface between humans, animals and ecosystems -- Part 6: Developing Strategies -- Chapter 17: Business for biodiversity and ecosystem services -- Chapter 18: Bridging the gap between conservation and health -- Chapter 19: Implementation of the One health strategy. Lessons learnt from community based natural resource programs for communities' empowerment and equity within an Eco health approach.
  • "The Sociology of Medical Screening: Critical Perspectives, New Directions presents a series of readings that provide an up-to-date overview of the diverse sociological issues relating to population-based medical screening. Features new research data in most of the contributions. Includes contributions from eminent sociologists such as David Armstrong, Stefan Timmermans, and Alison Pilnick. Represents one of the only collections to specifically address the sociology of medical screening"--Provided by publisher.
  • This title in the PROCEDURES IN COSMETIC DERMATOLOGY SERIES presents up-to-the-minute, practical guidance on soft tissue augmentation techniques shaping today's practice. Succinctly written and lavishly illustrated, it focuses on procedural how-to's and offer step-by-step advice on proper techniques, pitfalls, and tricks of the trade-so you can refine and hone your skills ... and expand your surgical repertoire. You'll find current, to-the-point guidance on the cosmetic use of traditional and new fillers-edited by pioneers in the field, Drs. Alastair and Jean Carruthers. Implement the newest procedures into your practice immediately and confidently-with the outstanding guidance you'll find in this volume of the PROCEDURES IN COSMETIC DERMATOLOGY SERIES. Get the best results from permanent fillers that stimulate the body's own collagen, new hypoallergenic fillers, injectable Zyderm and Zyplast collagen, and Gore-Tex chin, lip and cheek implants -all with one concise, accessible volume. Visualize techniques clearly with a wealth of color illustrations and photographs that depict cases as they appear in practice. Browse the fully searchable text online at, along with expanded video content and downloadable images.
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  • Nature, distribution, and origin of soil materials in the forensic comparison of soils / Robert W. Fitzpatrick -- Cadaver decomposition and soil: processes / David O. Carter and Mark Tibbett -- The role of soil organisms in terrestrial decomposition / David W. Hopkins -- Soil fungi associated with graves and latrines: towards a forensic mycology / Naohiko Sagara, Takashi Yamanaka, and Mark Tibbett -- The role of invertebrates in terrestrial decomposition: forensic applications / Ian R. Dadour and Michelle L. Harvey -- The decomposition of hair in the buried body environment / Andrew S. Wilson -- The decomposition of materials associated with buried cadavers / Robert C. Janaway -- Decomposition chemistry in a burial environment / Shari L. Forbes -- Potential determinants of postmortem and postburial interval of buried remains / Shari l. Forbes -- Principles and methodologies of measuring microbial activity and biomass in soil / Phil Brookes -- Methods of characterizing and fingerprinting soils for forensic application / Lorna A. Dawson ... [et al.].
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    List of illustrations -- Foreword -- Preface -- Acknowledgments -- Introduction: Fuller's arrival in Germany, 1905 -- The beginning: John Lewis Fuller, Norfolk, Virginia, 1830 -- A new life in Africa: Monrovia, 1852 -- In pursuit of a dream: North Carolina, 1889 -- Learning and teaching: Boston, 1897 -- The science of German: Munich, 1904 -- The doctor and the sculptor: Westboro, 1906 -- Pioneer in American psychiatry: Framingham, 1909 -- Contributions to science and medicine: Westborough, 1911 -- The later years: Framingham, 1933 -- Recognition of accomplishments: Boston, 1974 -- Epilogue: Washington DC, 2001 -- Appendix: publications of Solomon Carter Fuller -- Notes -- About the author -- Index.
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    1. The Genetics Revolution in the Life Sciences -- pt. I. TRANSMISSION GENETICS -- 2. Single-Gene Inheritance -- 3. Independent Assortment of Genes -- 4. Mapping Eukaryote Chromosomes by Recombination -- 5. The Genetics of Bacteria and Their Viruses -- 6. Gene Interaction -- pt. II. FROM DNA TO PHENOTYPE -- 7. DNA: Structure and Replication -- 8. RNA: Transcription and Processing -- 9. Proteins and Their Synthesis -- 10. Gene Isolation and Manipulation -- 11. Regulation of Gene Expression in Bacteria and Their Viruses -- 12. Regulation of Gene Expression in Eukaryotes -- 13. The Genetic Control of Development -- 14. Genomes and Genomics -- pt. III. MUTATION, VARIATION, AND EVOLUTION -- 15. The Dynamic Genome: Transposable Elements -- 16. Mutation, Repair, and Recombination -- 17. Large-Scale Chromosomal Changes -- 18. Population Genetics -- 19. The Inheritance of Complex Traits -- 20. Evolution of Genes and Traits.
  • This book details a model of consciousness supported by scientific experimental data from the human brain. It presents how the Corollary Discharge of Attention Movement (CODAM) neural network model allows for a scientific understanding of consciousness as well as provides a solution to the Mind-Body problem. The book provides readers with a general approach to consciousness that is powerful enough to lead to the inner self and its ramifications for the vast range of human experiences. It also offers an approach to the evolution of human consciousness and features chapters on mental disease (especially schizophrenia) and on meditative states (including drug-induced states of mind). Solving the Mind-Body Problem bridges the gap that exists between philosophers of mind and the neuroscience community, allowing the enormous weight of theorizing on the nature of mind to be brought to earth and put under the probing gaze of the scientific facts of life and mind.
  • Nuclear remodeling and nuclear reprogramming for making transgenic pigs by nuclear transfer / Randall S. Prather -- Somatic cell nuclei in cloning : strangers traveling in a foreign land / Keith E. Latham, Shaorong Gao, and Zhiming Han -- Cloning cattle : the methods in the madness / Bjørn Oback and David N. Wells -- Centrosome inheritance after fertilization and nuclear transfer in mammals / Qing-Yuan Sun and Heide Schatten -- Developmental, behavioral, and physiological phenotype of cloned mice / Kellie L.K. Tamashiro ... [et al.] -- Nucleolar remodeling in nuclear transfer embryos / Jozef Laurincik and Poul Maddox-Hyttel -- Somatic cell nuclear transfer (SCNT) in mammals : the cytoplast and its reprogramming activities / Josef Fulka, Jr. and Helena Fulka -- Mitochondrial DNA inheritance after SCNT / Stefan Hiendleder -- Activation of fertilized and nuclear transfer eggs / Christopher Malcuit and Rafael A. Fissore.
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    1. Introduction: Narrativitzing the body -- 2. The Patient's body in Indian medical literature -- 3. Fever -- 4. Miscarriage -- 5. The King's disease -- 6. The Joy of life [Jīvānandanam] of Ānandarāyamakhin -- 7. Conclusion: Medical narratives and the narrativized patient.
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    Formation and differentiation of avian somite derivatives / Bodo Christ and Martin Scaal -- Avian somitogenesis : translating time and space into pattern / Beate Brand-Saberi, Stefan Rudloff, and Anton J. Gamel -- Genetic analysis of somite formation in laboratory fish models / Christoph Winkler and Harun Elmasri -- Old wares and new : five decades of investigation of somitogenesis in Xenopus laevis / Duncan B. Sparrow -- Role of delta "like" in mammalian somitogenesis and vertebral column formation / Gavin Chapman and Sally L. Dunwoodie -- Mesp-family genes are required for segmental patterning and segmental border formation / Yumiko Saga and Yu Takahashi -- BHLH proteins and their role in somitogenesis / Miguel Maroto ... [et al.] -- Mouse mutations disrupting somitogenesis and vertebral patterning / Kenro Kusumi, William Sewell, and Megan L. O'Brien -- Defective somitogenesis and abnormal vertebral segmentation in man / Peter D. Turnpenny.
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    Introduction -- Ultrasound -- Transducers -- Instruments -- Doppler principles -- Artifacts -- Performance and safety -- Review.
  • Sorting and Recycling Endosomes provides the latest information on endosomes, the receiving compartment for endocytosed cargos, and the donor compartment and sorting station for cargos designated to lysosomes, Golgi, or plasma membrane. In recent years, the importance of endosomes as a sorting and recycling compartment has become increasingly appreciated. As such, scientists from various fields of cell biology, membrane traffic, and beyond, see the needs to communicate and learn about the methods used to investigate the dynamics and functions of endosomes. This book brings together specialists from the field who contribute their expertise on a broad range of biomedical topics that will provide ideal reading for researchers interested in endosomal sorting and recycling. This volume covers the approaches necessary to study the key components that mediate the generation and transport of membrane-bounded carriers from the endosomes, and how membrane trafficking machinery is coordinated with cytoskeletons during these processes. In addition to studies carried out in mammalian cells, other model systems such as worm and yeast are also included.
  • Introduction to sound source localization / Richard R. Fay and Arthur N. Popper -- Directional hearing in insects / Daniel Robert -- Sound source localization by fishes / Richard R. Fay -- Directional hearing in nonmammalian tetrapods / Jakob Christensen-Dalsgaard -- Comparative mammalian sound localization / Charles H. Brown and Bradford J. May -- Development of the auditory centers responsible for sound localization / M. Fabiana Kubke and Catherine E. Carr -- Interaural correlation as the basis of a working model of binaural processing: an introduction / Constantine Trahiotis, Leslie R. Bernstein, Richard M. Stern, and Thomas N. Buell -- Models of sound localization / H. Steven Colburn and Abhijit Kulkarni.
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    Paleopathology and primitive medicine -- The Middle East in antiquity -- China and India in antiquity -- Greece -- Rome and Byzantium -- Europe, 500-1500 -- Medicine in the Muslim world and the Americas, 700-1500 -- The Renaissance and the scientific revolution: technical and theoretical change -- Europe, 1500-1800: health, disease, trauma, and society -- The nineteenth century: the development and spread of Western medicine -- The nineteenth century: change and upheaval -- The twentieth century: advances and challenges -- The twentieth century: new enemies, old nemeses -- A brave new century: dilemmas in twenty-first-century medicine.
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    Women living with HIV -- The Cape Coloured community -- A support group for HIV-positive women in Cape Town -- Marginalizing the marginalized through multiple stigmas -- Disclosure for better or worse -- Staking a claim as normal through work and relationships with men -- Care work -- Care work and violent men -- Women's bodies -- Lessons for the world.
  • As America's most populous state goes, so goes the nation. And within that state, the 38 counties comprising South Texas--a highly populated, largelyHispanicarea characterized by high uninsured rates and low numbers of health care providers--are emblematic of nationwide crises in public health. The South Texas Health Status Review: A Health Disparities Roadmapbrings health care disparities to light in instructive detail. Over thirty key health conditions and risk factors, such as breast cancer, diabetes, obesity, tuberculosis, smoking and alcohol use, lead exposure, birth defects, and homicide rates, are analyzed by age, sex, race/ethnicity, and location (urban or rural), and the results compared with the rest of Texas and the nation as a whole. A section on conclusions and recommendations outlines factors contributing to these conditions and offers suggestions for improvement. These important data should stimulate further population studies and provide impetus for targeted public health interventions and community outreach programs to reduce health inequities and advance care access in the state and the U.S. at large. Major health issues covered in the report include: Communicable diseases Cancer incidence and mortality Maternal and child health Chronic diseases Behavioral risk factors in adults Environmental health issues Suicide, homicide, and vehicular mortality The South Texas Health Status Reviewcontains valuable lessons for researchers in health promotion and health disparities, as well as community health professionals. Policymakers involved in reducing health disparities will find it especially useful.
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  • Chapter 1. Historical Aspects -- Introduction -- Importance of Soy Protein Products -- Chapter 2. Definitions and Methods of Preparation -- Introduction -- Soy Flours and Grits -- Partially Defatted Extruded-Expelled Soy Flours -- Textured Soy Flour -- Soy Protein Concentrates -- Textured Soy Protein Concentrates -- Soy Protein Isolates -- Structured Isolates -- Speciality Soy Foods and Ingredients -- Chapter 3. Protein Quality and Human Nutrition -- Introduction -- Factors Affecting Protein Quality -- Amino Acid Composition -- Amino Acid Requirements -- Digestibility -- Protein Digestibility-Corrected Amino Acid Score (PDCAAS) -- Evaluation of Soy Protein Products in Human Nutrition -- Evaluation of Soy Protein Products in Specific Foods -- Infant Formulas -- Meats and Fish -- Special Nutritional Products -- Mixtures of Soy Bean and Cereal Grains and Alternate -- Protein Sources -- Mineral Content and Mineral Bioavailability -- Sodium -- Bioavailability of Minerals (excluding Iron) -- Bioavailability of Iron -- Calories -- Nutritional Significance of Protease Inhibitors -- Chapter 4. Health and Soy Protein -- Introduction -- Coronary Heart Disease -- Calorie Control -- Dietary Fiber -- Additional Nutritional Issues -- Carbohydrates and Flactulence -- Immunochemical Properties -- Safety, Microbiology, and Sanitation Toxic Factors -- Microbiology and Sanitation -- Chapter 5. Functionality of Soy Proteins -- Introduction -- Functionality of Soy Protein Ingredients -- Soy Flours and Grits -- Soy Protein Concentrates -- Soy Protein Isolates -- Soy Protein Hydrolyzates -- Texture and Structured Soy Protein Products -- Textured Soy Flours and Concentrates -- Structured Isolates -- Chapter 6. Uses in Food Systems -- Introduction -- Bakery Products -- Milk Replacers -- Bread and Rolls -- Specialty Bread -- Cakes and Cake Mixes -- Cookies, Crackers, Biscuits, Pancakes, and Sweet Pastry -- Doughnuts -- Pasta Products -- Breakfast Cereals -- Dairy-Type Products -- Beverages and Toppings -- Infant Formulas and Special Nutritional Products -- Milk Replacers For Young Animals -- Meat Products -- Emulsified Meat Products -- Coarsely Chopped (Ground) Meats -- School Lunch and Military Uses -- Canned Meats -- Whole Muscle Meats -- Poultry Products -- Seafood Products -- Analog Products -- Miscellaneous Foods -- Chapter 7. Regulations Regarding Usage -- Introduction -- Meat and Poultry Products -- Bakery Products and Pasta -- Dairy Products and Margarine/Edible Spreads -- Formulated Foods -- Chapter 8. Future Considerations -- Introduction -- Economics -- References.
  • "The study of mathematical cognition and the ways in which the ideas of space, time and number are encoded in brain circuitry has become a fundamental issue for neuroscience. How such encoding differs across cultures and educational level is of further interest in education and neuropsychology. This rapidly expanding field of research is overdue for an interdisciplinary volume such as this, which deals with the neurological and psychological foundations of human numeric capacity. A uniquely integrative work, this volume provides a much needed compilation of primary source material to researchers from basic neuroscience, psychology, developmental science, neuroimaging, neuropsychology and theoretical biology."--Publisher's description.
  • Cerebral palsy detection : from John Little to the present / Giovanni Cioni, Paola B. Paolicelli -- Guide to the interpretation of cerebral palsy / Adriano Ferrari, Silvia Alboresi -- Functional diagnosis in infants and in very young children : early predictive signs / Giovanni Cioni, Andrea Guzzetta, Vittorio Belmonti -- Motor defects / Adriano Ferrari -- Perceptive defects / Adriano Ferrari -- Praxic organization disorders / Simonetta Muzzini, Federico Posteraro, Roberta Leonetti -- Visual and oculomotor disorders / Andrea Guzzetta ... [et al.] -- Neuropsychological evaluation / Daniels Brizzolara, Paola Brovedani, Giovanni Ferretti -- Emotional, behavioral and social disorders in children and adolescents with cerebral palsy / Gabriele Masi, Paolo Brovedani -- Observing interactions / Sandra Maestro -- Critical aspects of classifications / Adriano Ferrari -- Kinematic classification / Adriano Ferrari -- Tetraplegic forms / Adriano Ferrari ... [et al.] -- Dysperceptive forms / Silvia Alboresi ... [et al.] -- Forms of diplegia / Adriano Ferrari ... [et al.] -- Forms of hemiplegia / Giovanni Cioni ... [et al.].
  • Statistical analysis of spatial structure in microbial communities / Rima B. Franklin, Aaron L. Mills -- Bacterial interactions at the microscale - linking habitat to function in soil / Naoise Nunan ... [et. al] -- Spatial distribution of bacteria at the microscale in soil / Arnaud Dechesne, Céline Pallud, Geneviève L. Grundmann -- Analysis of spatial patterns of rhizoplane colonization / Guy R. Knudsen, Louise-Marie Dandurand -- Microbial distributions and their potential controlling factors in terrestrial subsurface environments / R. Michael Lehman -- Spatial organisation of soil fungi / Karl Ritz -- Spatial heterogeneity of planktonic microorganisms in aquatic systems / Bernadette Pinel-Alloul, Anas Ghadouani -- The interrelationship between the spatial distribution of microorganisms and vegetation in forest soils / Sherry J. Morris, William J. Dress.
  • GIS concepts and operations -- GIS and geographic data -- Spatial analysis software and methods -- Point pattern methods of disease analysis -- Areal methods of disease analysis -- Interpolation and associative analysis -- Initiating a GIS project in spatial epidemiology -- Current GIS research in health care and disease analyses.
  • This volume is a cutting-edge review of the latest findings on key scientific and clinical issues in hypertension, with an integration of different new specific topics into the general knowledge of how to understand the pathophysiology and correctly diagnose and treat this chronic condition, which still represents the first cause of death in the world.Among the topics included in the book the reader will find some forms of hypertension which are frequently encountered in clinical practice and on which new important evidence is available, such as high-normal blood pressure (also termed pre-hypertension), white-coat and masked hypertension, and high blood pressure in the elderly and the very elderly. These emerging aspects are discussed in detail, along with chapters on issues of great current interest, such as the way to assess and how to treat asymptomatic organ damage, emerging cardiovascular risk factors such as short and long-term blood pressure variability, cognitive impairment and dementia. The book also deals with the changing concepts in the management of hypertension and antihypertensive pharmacotherapy, and addresses specific topics which are rarely discussed in clinical medicine volumes, including hypertension in post-menopausal women, hormonal replacement therapy, inflammatory disorders, sexual dysfunction with treatment, and the effect of Ramadan fasting on blood pressure. This ready to hand but encompassing volume proves to be a comprehensive updating tool to professionals and clinical practitioners managing patients with hypertension.
  • Special Procedures in Foot and Ankle Surgery is designed for foot and ankle surgeons who desire to take their skill set to the next level. Advanced surgical techniques are highlighted for some of the more difficult problems encountered by foot and ankle surgeons such as Charcot deformity, chronic tendinopathies, osteochondral lesions, total ankle arthroplasty, tumors, adult flatfoot, cavus and Rheumatoid foot. The latest techniques, including endoscopic approaches are highlighted. This book is designed for all levels of foot and ankle surgeons to better care for their patients.
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  • Pattern recognition by B cells: the role of antigen repetitiveness versus toll-like receptors -- The multifunctional role of antibodies in the protective resonse to bacterial T cell-independent antigens -- The important anddiverse roles of antibodies in the host response to Borrelia infections -- A distinct role for B1b lymphocytes in T cell-independent immunity -- Secretory immunity following mutans streptococcal infection or immunization.
  • 1. What We Know About Factors Affecting Medical Student & Resident Career Decisions -- 2. Study Aims, Questions, Methods, Limitations -- 3. Outcomes of Current Physician Training -- 4. Debt -- 5. Title VII Effect, Personal Interests, and Experiences in Medical School -- 6. Return on Investment -- 7. Conclusions and Recommendations -- Appendices.
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    This illustrated reference is a practical guide to the use of arthrography in conjunction with MRI and CT for accurate diagnosis of musculoskeletal injuries and diseases. The opening general principles section includes chapters on arthrographic appearance of arthritides, basic techniques, therapeutic injections, tenosynography, and ultrasound-guided aspiration. Subsequent sections focus on the shoulder, elbow, wrist, hip, sacroiliac joint, knee, ankle, and foot. Each section includes an explanation of arthrographic procedures and pitfalls; an atlas of relevant articular anatomy; diagnostic criteria and differential diagnoses for specific injuries and diseases; and a chapter on postoperative findings. The format features succinct, bulleted text and hundreds of illustrations with detailed legends.
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    In this comprehensive work, John S. Wilkins traces the history of the idea of "species" from antiquity to today, providing a new perspective on the relationship between philosophical and biological approaches.--[Book cover].
  • This new volume on gene expression and epigenetics discusses environmental effects related to specific gene expression. The book also shows methods for bioinformatic analysis of the epigenome. The book is broken into two sections: the first looks at eukaryotic DNA methylation and the second addresses how to integrate genomic medicine into clinical practice. The book includes chapters on these topics: Gene expression in colon cancer tissue Epigenetics in human acute kidney injury Embryologically relevant candidate genes in MRKH patients DNA methylation in common skeletal disorders Causal relat.
  • The systems-based approach to proteomics and chemical proteomics / Daniel S. Sem -- Similarities in protein binding sites / Hugo O. Villar, Mark R. Hansen, and Richard Kho -- Survey of spectral techniques used to study proteins / Daniel S. Sem -- Capillary electrophoresis, mass spectrometry for characterization of peptides and proteins / Christian Neusüss and Matthias Pelzing -- Protein and peptide analysis by matrix-assisted laser desorption/ionization tandem mass spectrometry (Maldi MS/MS) / Emmanuelle Sachon and Ole Nørregaard Jensen -- Characterization of glycosylated proteins by mass spectrometry using microcolumns and enzymatic digestion / Per Hägglund and Martin R. Larsen -- Surface-enhanced laser desorption/ionization protein biochip technology for proteomics research and assay development / Scot R. Weinberger ... [et al.] -- An approach to the reproducibility of SELDI profiling / Walter S. Liggett ... [et al.] -- Mass spectrometric applications in immunoproteomics / Anthony W. Purcell ... [et al.] -- Near-infrared fluorescence detection of antigen-antibody interactions on microarrays / Sakanyan Vehary and Yeretssian Garabet -- Application of shotgun proteomics to transcriptional regulatory pathways / Amber L. Mosley and Michael P. Washburn -- Electrophoretic NMR of protein mixtures and its proteomic applications / Qiuhong He, Sunitha B. Thakur, and Jeremy Spater -- Characterizing proteins and proteomes using isotope-coded mass spectrometry / Uma Kota and Michael B. Goshe -- Surface plasmon resonance biosensors’ contributions to proteome mapping / Rebecca L. Rich and David G. Myszka -- Application of in-cell NMR spectrocopy to investigation of protein behavior and ligand-protein interaction inside living cells / Volker Dötsch -- An overview of metabonomics techniques and applications / John C. Lindon, Elaine Holmes, and Jeremy K. Nicholson -- NMR-based structural proteomics / John L. Markley -- Leveraging x-ray structural information in gene family-based drug discovery: application to protein kinases / Marc Jacobs ... [et al.] -- EPR spectroscopy in genome-wide expression studies / Richard Cammack -- Summary of chapters and future prospects for spectral techniques in proteomics / Daniel S. Sem.
  • v. 2, 2006 Springer
    v. 3, 2006 Springer
    v. 4, 2006 Springer
    v. 5, 2006 Springer
    v. 6, 2006 Springer
    v. 1. Cholestanes, ergostanes, withanolides, stigmastane -- v. 2. Stigmastanes, furostanes, spirtostanes-- v. 3. Spirostanes, bufanolides, cardenolides-- v. 4. Cardenolides and pregnanes -- v. 5. Pregnanes, androstanes, and miscellaneous -- v. 6. Miscellaneous steroids and indexes.
  • Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage.
  • No evidence for killer sperm or other selective interactions between human spermatozoa in ejaculates of different males in vitro (1999) / Harry D.M. Moore, M. Martin & Tim R. Burkhead -- Psychological adaptation to human sperm competition (2002) / Todd K. Shackelford ... [et al.] -- Semen displacement as a sperm competition strategy in humans (2004) / Gordon G. Gallup & Rebecca L. Burch -- Human female orgasm and male fluctuating asymmetry (1995) / Randy Thornhill, Steve W. Gangestad & Randall Comer. Sperm competition in humans / Nicholas Pound, Todd K. Shackelford, Aaron T. Goetz -- Why are there so many tiny sperm? Sperm competition and the maintenance of two sexes (1982) / Geoffrey A. Parker -- Sperm competition, male prudence, and sperm-limited females (2002) / Nina Wedell, Matthew J.G. Gage & Geoffrey A. Parker -- Human sperm competition (1984) / Robert L. Smith -- "Kamikaze" sperm in mammals? (1988) / R. Robin Baker & Mark A. Bellis -- Deformed sperm are probably not adaptive (1989) / Alexander H. Harcourt -- Elaboration of the kamikaze sperm hypothesis: a reply to Harcourt (1989) / R. Robin Baker & Mark A. Bellis -- Number of sperm in human ejaculates varies in accordance with sperm competition theory (1989) / R. Robin Baker & Mark A. Bellis -- Do females promote sperm competition? Data for humans (1990) / Mark A. Bellis & R. Robin Baker -- Human sperm competition: ejaculate adjustment by males and the function of masturbation (1993) / R. Robin Baker & Mark A. Bellis -- Human sperm competition: ejaculate manipulation by females and a function for the female orgasm (1993) / R. Robin Baker & Mark A. Bellis --
  • Sphingolipid metabolism and analysis in metabolic disease / Sarah E. Brice and L. Ashley Cowart -- Sphingolipids and cardiovascular diseases : lipoprotein metabolism, atherosclerosis and cardiomyopathy / Xian Cheng Jiang, Ira J. Goldberg, and Tae Sik Park -- Heart sphingolipids in health and disease / Marcin Baranowski and Jan Grski -- Blood sphingolipids in homeostasis and pathobiology / Samar M. Hammad -- Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity / Fahumiya Samad ... [et al.] -- Sphingolipids and hepatic steatosis / Benjamin T. Bikman and Scott A. Summers -- Glycosphingolipids and insulin resistance / Johannes M. Aerts ... [et al.] -- Glycosphingolipids and kidney disease / Andrew R. Mather and Leah J. Siskind -- Sphingolipid synthetic pathways are major regulators of lipid homeostasis / Tilla S. Worgall.
  • An overview of sphingolipid metabolism : from synthesis to breakdown / Christopher R. Gault, Lina M. Obeid, and Yusuf A. Hannun -- Sphingolipid transport / Laura Riboni, Paola Giussani and Paola Viani -- Sphingolipid analysis by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) / Jacek Bielawski ... [et al.] -- Ceramide synthases : roles in cell physiology and signaling / Johnny Stiban, Rotem Tidhar and Anthony H. Futerman -- Tales and mysteries of the enigmatic sphingomyelin synthase family / Joost C.M. Holthuis and Chiara Luberto -- Ceramide in stress response / Mariana N. Nikolova-Karakashian and Krassimira A. Rozenova -- Animal models for studying the pathophysiology of ceramide / Toshihiko Kawamori -- Ceramide 1-phosphate in cell survival and inflammatory signaling / Antonio Gómez-Muñoz ... [et al.] -- Ceramide-1-phosphate in phagocytosis and calcium homeostasis / Vania Hinkovska-Galcheva and James A. Shayman -- Extracellular and intracellular actions of sphingosine-1-phosphate / Graham M. Strub ... [et al.] -- Glucosylceramide in humans / Maria C. Messner and Myles C. Cabot -- Gangliosides as regulators of cell membrane organization and functions / Sandro Sonnino and Alessandro Prinetti -- Cancer treatment strategies targeting sphingolipid metabolism / Babak Oskouian and Julie D. Saba -- Therapeutic strategies for diabetes and complications : a role for sphingolipids? / Todd E. Fox and Mark Kester -- Roles for sphingolipids in Saccharomyces cerevisiae / Robert C. Dickson -- Sphingolipid signaling in fungal pathogens / Ryan Rhome and Maurizio Del Poeta -- Sphingolipids in parasitic protozoa / Kai Zhang, James D. Bangs and Stephen M. Beverley -- Biosynthesis of sphingolipids in plants (and some of their functions) / Simone Zäuner, Philipp Ternes, and Dirk Warnecke -- Computational analysis of sphingolipid pathway systems / Eberhard O. Voit, Fernando Alvarez-Vasquez, and Yusuf A. Hannun.
  • Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids' basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.
  • Sphingolipids in Cancer. Sphingosine Kinase/Sphingosine 1-Phosphate Signaling in Cancer Therapeutics and Drug Resistance / Shanmugam Panneer Selvam, Besim Ogretmen -- Using ASMase Knockout Mice to Model Human Diseases / Guoqiang Hua, Richard Kolesnick -- New Perspectives on the Role of Sphingosine 1-Phosphate in Cancer / Susan Pyne, Nigel J. Pyne -- Sphingolipids and Response to Chemotherapy / Marie-Thérèse Dimanche-Boitrel, Amélie Rebillard -- Lung Cancer and Lung Injury: The Dual Role of Ceramide / Tzipora Goldkorn, Samuel Chung, Simone Filosto -- Sphingolipids' Role in Radiotherapy for Prostate Cancer / Carla Hajj, Adriana Haimovitz-Friedman -- Sphingolipids in Cardio-Reno-vascular Diseases. Sphingolipid Metabolism and Atherosclerosis / Xian-Cheng Jiang, Jing Liu -- Cardiovascular Effects of Sphingosine-1-Phosphate (S1P) / Bodo Levkau -- Cross Talk Between Ceramide and Redox Signaling: Implications for Endothelial Dysfunction and Renal Disease / Pin-Lan Li, Yang Zhang -- Sphingolipids in Inflammation, Infection and Lung Diseases. Sphingolipids in Lung Endothelial Biology and Regulation of Vascular Integrity / Taimur Abbasi, Joe G. N. Garcia -- Sphingolipids in Acute Lung Injury / Stefan Uhlig, Yang Yang -- The Involvement of Sphingolipids in Chronic Obstructive Pulmonary Diseases / Irina Petrache, Daniela N. Petrusca -- Ceramide in Cystic Fibrosis / Heike Grassmé, Joachim Riethmüller, Erich Gulbins -- Regulation of the Sphingosine Kinase/Sphingosine 1-Phosphate Pathway / K. Alexa Orr Gandy, Lina M. Obeid -- Bacterial Infections and Ceramide / Heike Grassmé, Katrin Anne Becker -- Viral Infections and Sphingolipids / Jürgen Schneider-Schaulies, Sibylle Schneider-Schaulies -- Ceramide in Plasma Membrane Repair / Annette Draeger, Eduard B. Babiychuk -- Sphingolipids and Inflammatory Diseases of the Skin / Burkhard Kleuser, Lukasz Japtok -- Sphingolipids in Obesity, Type 2 Diabetes, and Metabolic Disease / S. B. Russo, J. S. Ross, L. A. Cowart -- Sphingolipids in Neuro-psychiatry and Muscle Diseases. Neuronal Forms of Gaucher Disease / Einat B. Vitner, Anthony H. Futerman Sphingolipids in Neuroinflammation / Laura Davies, Klaus Fassbender, Silke Walter -- Sphingolipids in Psychiatric Disorders and Pain Syndromes / C. Mühle, M. Reichel, E. Gulbins, J. Kornhuber -- Role of Sphingosine 1-Phosphate in Skeletal Muscle Cell Biology / Paola Bruni, Chiara Donati.
  • "This volume focuses on the role of sphingosine-1-phosphate (S1P) and its analogs in the induced sequestration of lymphocytes in secondary lymphoid organs or in the microenvironment of tissues involved in infection or autoimmune disease. Initial chapters define the pathways to understand S1P signaling. They cover the organization of signaling systems, the structural biology of the S1P1 receptor, and the chemical and genetic tools that are available and useful to explore this area of research and therapeutics. The later chapters highlight S1P and endothelial integrity, lymphocyte migration in the spleen, and S1P agonist in controlling immunopathologic manifestations of acute respiratory influenza virus infection (in the lung), and its accompanying cytokine storm as well as immunopathologic disease of the central nervous system, including the beginning of treatments in multiple sclerosis. One chapter reveals the possible involvement of other lipid molecules, their use for better understanding lipid signaling, and their potential in the modulation of immune responses."--Publisher's website.
  • Spine systems science : a primer on the systems approach / N. Peter Reeves, Jacek Cholewicki -- Computational models for trunk trajectory planning and load distribution : a test-bed for studying various clinical adaptation and motor control strategies of low back pain patients / Mohamad Parnianpour -- Mechanical changes in the spine in back pain / Greg Kawchuk -- Spine function and low-back pain : interactions of active and passive structures / Jaap H. van Dieen, Idsart Kingma -- Adaptation and rehabilitation: from motoneurones to motor cortex and -- Behaviour / Paul W. Hodges -- Opinions on the links between back pain and motor control : the disconnect -- Between clinical practice and research / Stuart McGill -- The kinesiopathologic model and mechanical low back pain / Linda R. Van Dillen, Shirley A. Sahrmann, Barbara J. Norton -- The relationship between control of the spine and low back pain : a clinical -- Researcher's perspective / Julie A. Hides -- Existing muscle synergies and low back pain : a case for preventative -- Intervention / Jack P. Callaghan, Erika Nelson-Wong -- Trunk muscle control and back pain : chicken, egg, neither or both? / G. Lorimer Moseley -- Altered variability in proprioceptive postural strategy in people with recurrent low back pain / Simon Brumagne ... [et al.] -- Proprioceptive contributions from paraspinal muscle spindles to the relationship between control of the trunk and back pain / Joel G. Pickar -- Time-dependent mechanisms that impair muscle protection of the spine / Patricia Dolan, Michael A. Adams -- Effectiveness of exercise therapy for chronic non-specific low-back pain / Marienke van Middelkoop .... [et al.] -- How can models of motor control be useful for understanding low back pain? (summary chapter 1) / N. Peter Reeves ... [et al.] -- Targeting interventions to patients : development and evaluation (summary chapter 2) / Linda van Dillen, Maurits van Tulder -- Motor control changes and low-back pain, cause or effect? (summary chapter 3) / Jaap H. van Dieen, G. Lorimer Moseley, Paul W. Hodges -- What is the relation between proprioception and low back pain? (summary chapter 4) / Simon Brumagne, Patricia Dolan, Joel G. Pickar -- Motor control of the spine and changes in pain : debate about the extrapolation from research observations of motor control strategies to effective treatments for back pain (summary chapter 5) / Paul W. Hodges, Stuart McGill, Julie A. Hides -- Integrated clinical approach to motor control interventions in low back and pelvic pain / Paul W. Hodges ... [et al.].
  • The organization of the spinal cord / Charles Watson and Gulgun Kayalioglu -- Development of the spinal cord / Kens WS Ashwell -- The vertebral column and spinal meninges / Gulgun Kayalioglu -- The spinal nerves / Gulgun Kayalioglu -- The spinal cord blood vessels / Oscar U. Scremin -- Cytoarchitecture of the spinal cord / Claire Heise and Gulgun Kayalioglu -- Localization of motoneurons in the spinal cord / Steve McHanwell and Charles Watson -- Spinal autonomic preganglionic neurons: the visceral efferent system of the spinal cord / Colin R. Anderson, Janet R. Keast and Elspeth M. McLachlan -- Central nervous system control of micturition / Gert Holstege and Han Collewijn -- Projections from the spinal cord to the brain / Gulgun Kayalioglu -- Projections from the brain to the spinal cord / Charles Watson and Alan R. Harvey -- The propriospinal system / Amanda C. Conta and Dennis J. Stelzner -- Spinal cord transmitter substances / Claire Heise and Gulgun Kayalioglu -- Spinal cord injury: experimental animal models and relation to human therapy / Stuart I. Hodgetts, Giles W. Plant and Alan R. Harvey -- Atlas of the rat spinal cord / Charles Watson ... [et al.] -- Atlas of the mouse spinal cord / Charles Watson ... [et al.] -- Toward a spinal cord ontology / Charles Watson and Amandeep Sidhu.
  • Presents authorataive coverage of state-of-the-art techniques for diagnosing and managing tumors of the spine and spinal cord. Covers fundamentals of spinal cord anatomy and the pathology of spinal tumors to evaluation, diagnosis, and treatment techniques for specific spinal tumors.
  • Spinal cord injury 2012
    Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury. Comprehensive coverage of the latest scientific understanding of spinal cord injuries Detailed coverage of current treatment best practices and potential future treatments Connects leading edge research programs to future treatment opportunities .
  • Section I. Spinal cord injuries in patients -- Section II. Spinal cord injuries in animal models -- Section III. Neuroprotection and transplantation -- Section IV. Molecular targets to promote axon regeneration in the CNS.
  • 1. The History and Overview of Spinal Deformity -- 2. Measuring Value in Spinal Deformity Care -- 3. Intraoperative Neuromonitoring in Spinal Deformity Surgery -- 4. Anatomy and Evaluation of Spinal Alignment -- 5. Anatomical Variants with Spinal Deformity -- 6. The Importance of the Sacrum and Pelvis in Deformity Evaluation and Treatment -- 7. The Lenke Classification System for Adolescent Idiopathic Scoliosis -- 8. Principles of Sagittal Plane Deformity -- 9. Principles of Coronal Plane Deformity -- 10. Flexible versus Fixed Spinal Deformity -- 11. The Natural History of Spinal Deformity -- 12. Congenital Scoliosis -- 13. Early-Onset Scoliosis -- 14. Neuromuscular Scoliosis -- 15. Anterior Surgery for Thoracic Scoliosis -- 16. Posterior Approach in Thoracic Deformity -- 17. Lateral Interbody Fusion Approaches in Spinal Deformity -- 18. Anterior-Posterior Surgery for Spinal Deformity -- 19. Minimally Invasive Surgery for Adult Spinal Deformities -- 20. Scheuermann Kyphosis -- 21. Technological Advances in Spinal Deformity -- 22. Surgery for Adult Spinal Deformity -- 23. Osteotomies and Vertebral Column Resections for Complex Spinal Deformities -- 24. Adult Spinal Deformity Revision Surgery -- 25. Surgical Treatment of Spondylolisthesis -- 26. Prevention and Treatment of Posttraumatic Deformity of the Thoracolumbar Spine -- 27. Bracing and Nonoperative Treatment of Spinal Deformity.
  • Spinal imaging 2008
    Thieme Book
    1. Congenital malformations -- Arnold-Chiari malformation -- Lumbarization and sacralization -- Diastematomyelia -- Tethering -- Sacrococcygeal teratoma -- Meningocele, myelomeningocele -- Vertebral malformations -- Klippel-Feil syndrome -- Kyphosis -- Scheuermann disease -- Scoliosis -- Malrotation -- 2. Trauma -- Spinal injury-magerl classification -- Vertebral fractures-causes -- Dens fracture -- Flexion fracture of the cervical spine -- Burst fracture of the spine -- Chance fracture (seat belt fracture) -- Jefferson fracture -- Hangmans's fracture -- Spinal cord trauma -- Syringohydromyelia -- Anterior subluxation -- Insufficiency fracture of the sacrum -- Stress phenomena in the spine -- Stress fractures in ankylosing spondylitis -- 3. Degenerative disorders -- Disk degeneration -- Degenerative disk disease modic I -- Degenerative disk disease modic II -- Spondylosis deformans-modic III -- Disk herniation -- Bulge, protrusion, extrusion, sequestration -- Disk calcification and vacuum phenomenon -- Facet joint degeneration -- Uncovertebral osteoarthritis -- Synovial cyst -- Hypertroply of the ligamenta flava -- Baastrup disease -- Spongylolisthesis and pseudospondylolisthesis -- Degenerative spinal stenosis -- Diffuse idiopathic skeletal hyperostosis -- 4. Inflammatory disorders -- Rheumatoid arthritis -- Rheumatoid arthritis-chronic trauma -- Psoriatic spondyloarthropathy -- Reiter syndrome -- Ankylosing spondylarthropathy -- Ankylosing spondylitis-ligament calcification and bamboo spine -- Ankylosing psondylitis-fractures --Acute bacterial spondylitis -- Tuberculous spondylitis -- Epidural abscess -- Granulomatous inflammations of the spinal cord -- Arachnoiditis -- Acute transverse myelitis -- Spinal Multiple sclerosis --; 5. Tumors -- Hemangioma -- Osteoid osteoma -- Osteoblastoma -- Osteochondroma -- Aneurysmal bone cyst -- Giant cell tumor -- Langerhans cell histiocytosis -- Malignant tumors -- Bone metastases -- Multiple myeloma -- Chordoma -- Ewing sarcoma -- Lymphoma -- Nerve sheath tumors -- Leptomeningeal and intramedullary metastases -- Meningioma -- Ependymoma -- Astrocytoma -- Hemangioblastoma -- 6. Vascular disorders -- Epidural hematoma -- Arteriovenous malformation -- Arterial spinal cord infarction -- 7. Postoperative disorders -- Failed back surgery syndrome -- CSF fistula -- Peridural fibrosis -- Rapidly progressive osteoarthritis (after intersegmental fusion) -- Complications of spinal instrumentation -- 8. Metabolic disorders -- Senile and postmenopausal osteoporosis -- Paget disease -- Spinal epidural lipomatosis.
  • Spinal injection techniques 2009
    Thieme eNeurosurgery
    1. Basic principles -- 2. Diagnostics -- 3. Causal orthopedic pain therapy -- 4. Symptomatic pain therapy -- 5. The spine : anatomy, nociception, and the distribution of pain signals -- 6. Special orthopedic injection therapy : contraindications and patient information -- 7. Cervical injection therapy -- 8. Thoracic injection therapy -- 9. Lumbar injection therapy -- 10. General and specific complications and treatment measures -- 11. Multimodal spinal therapy -- 12. Summary.
  • Sect. I. General considerations. 1. History of spine injections / Sheryl L. Johnson and Kevin E. Vorenkamp -- 2. Therapeutic agents for spine injection: local anesthetics, steroids, and contrast media / Matthew J. Pingree and Marc A. Huntoon -- 3. Fluoroscopy, ultrasonography, computed tomography, and radiation safety / Stanley Golovac -- Sect. II. Peripheral nerve blocks. 4. Differential diagnostic nerve blocks / Jerald Garcia, I. Elias Veizi, and Salim M. Hayek -- 5. Head and neck blocks / Samer Narouze -- 6. Upper extremity peripheral nerve blockade / Hugh M. Smith and Christopher M. Duncan -- 7. Lower limb blacks / Padraig Mahon and Colin J.L. McCartney -- 8. Cervical and lumbar sympathetic blocks / Samer Narouze and Sean Graham -- 9. Nerve destruction for the alleviation of visceral pain / Kacey A. Montgomery and Robert W. Hurley -- 10. Peripheral applications of ultrasonography for chronic pain / Philip Peng -- Sect. III. Injections for back pain. 11. Therapeutic epidural injections: interlaminar and transoraminal / Marc A. Huntoon and Abram H. Burgher -- 12. Facet (zygapophyseal) intraarticular joint injections: cervical, lumbar, and thoracic / Jason E. Pope and Jianguo Cheng -- 13. Medial branch blocks: cervical, thoracic, and lumbar / Seth A. Waldman, Vinita Parikh, and Dawood Sayed -- 14. Radiofrequency rizotomy for facet syndrome / Jan van Zundert ... [et al.] -- 15. Sacroiliac joint injections and lateral branch blocks, including water-cooled neurotomy / Bryan S. Williams -- 16. Pulsed radiofrequency / Khalid Malik and Honorio T. Benzon -- 17. Discogenic pain and discography for spinal injections / Stanley Golovac -- 18. Minimally invasive intradiscal procedures for the treatment of discogenic lower back and leg pain / Leonardo Kapural and Dawn A. Sparks -- 19. Vertebral augmentation / Tristan C. Pico, Basem Hamid, and Allen W. Burton -- 20. Ultrasound-guided lumbar spine injections / Manfred Greher -- 21. Ultrasound-guided cervical spine injections / Samer Narouze -- 22. Musculoskeletal injections: iliopsoas, quadratus lumborum, piriformis, and trigger point injections / Anne Marie McKenzie-Brown, Kiran Chekka, and Honorio T. Benzon -- 23. Ultrasound-guided and fluoroscopically guided joint injections / Steve J. Wisniewski and Mark-Friedrich B. Hurdle.
  • Spinal Injuries and Conditions in Young Athletes provides a comprehensive, in-depth review of the mechanisms and management of back injuries and problems occurring in this ever-growing and active population. Led by Dr. Lyle Micheli and his co-editors, an award-winning group of orthopedists discusses and explores common adolescent spine injuries and procedures, in addition to breakthroughs in gene therapy, tissue engineering, and complex operations. As spine surgery is among the most complex and challenging procedures performed in orthopedics, special considerations and procedures are required in pediatric populations. Since many corrective surgeries run the risk of arthritis later in life, particular efforts must be made in young populations to prevent future injury in a child's adolescence and young adulthood while maximizing return-to-play potential. Chapters cover acute spinal injuries, concussions, overuse injuries, spinal malformations, tumors, infections and inflammatory diseases across the range of athletics, including swimming and combat sports. Spinal Injuries and Conditions in Young Athletes provides an immeasurable guide for back surgery in pediatric populations and will be a go-to resource for practitioners and residents in pediatric orthopedics and sports medicine.
  • Spinal instability 2015
    This easy-to-consult guide describes new minimally invasive procedures for the treatment of spinal instability that are accompanied by fewer complications and side-effects, reduce the risks of anesthesia, and lower costs. Clear accounts of a range of CT, X-ray, and MRI guided techniques are provided, including radiofrequency ablation in facet syndrome, cervical spine fusion, posterior and anterior lumbar spine fusion, and lumbosacral fusion. A brief but comprehensive introduction is included on biomechanics, relevant clinical syndromes, and diagnostic imaging. Like other books in the Springer series New Procedures in Spinal Interventional Neuroradiology, this practice-oriented volume will fill a significant gap in the literature and meet the need expressed by a large number of specialists (interventional neuroradiologists and radiologists, neurosurgeons, and orthopedists) for a topical and handy guide that specifically illustrates the presently available materials and methods.
  • Provides a complete guide to all contemporary forms of spinal implant systems. It not only highlights the newest devices, but also the clinical guidelines needed to choose and apply the best implant for any surgical situation. Along with an all-inclusive list of the spinal instruments available today, the book offers direct comparisons of each system to help make an informed and confident selection. Includes valuable tips on insertion techniques and complication avoidance to maximize success in the operating room. And, thousands of graphics ensure a lucid understanding of all implants and their applications.
  • Spinal osteotomy 2015
    Spinal osteotomy techniques have been dramatically applied as a standard method for severe and rigid spinal deformity. Although clinical results indicate that patients who undergo osteotomy procedures typically experience well deformity correction and ameliorate the clinical appearance, aggressive peri-operative risks and follow-up complications are not rare. More meticulous and standard indication selection, osteotomy plan design and complication prevention strategy and outcome evaluation are critically needed for surgeon majored in spine deformity. The book Spinal Osteotomy is divided into sections that focus on principles of spinal osteotomy, technical and case illustration and outcomes and complications as well as computer navigation and other latest techniques. Each section is heavily illustrated and clearly written for ease of understanding. Orthopedic surgeons, neurosurgeon residents and fellows who want to focus on spinal deformity correction will find this instructive and invaluable. Editor Yan Wang is a professor and dean of orthopedics department, Chinese PLA general hospital, China. Oheneba Boachie-Adjei, MD, is Chief of the Scoliosis Service, Hospital for Special Surgery, New York, NY, USA. Lawrence G. Lenke MD, is Professor and Chief of the Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.
  • Pathophysiology of spinal cord injury / B. Timothy Himes -- The neurological evaluation and medical management of acute spinal cord injury / Anthony S. Burns and Ralph J. Marino -- Surgical treatment of spinal injury / Daniel R. Fassett and James S. Harrop -- Controversies in clearing the spine / C. Craig Blackmore and Ken F. Linnau -- Plain film radiography and computed tomography of the cervical spine. Part I. Normal anatomy and spinal injury identification / Alejandro Zuluaga Santamaria and Diego B. Núñez, Jr. -- Plain film radiography and computed tomography of the cervical spine. Part II. Classification and subtypes of spinal injury / Alejandro Zuluaga Santamaria and Diego B. Núñez, Jr. -- Imaging of thoracolumbar spinal injury / George Koulouris, Amy Y.I. Ting, and William B. Morrison -- Magnetic resonance imaging of acute spinal trauma / Adam E. Flanders -- Imaging of pediatric spinal trauma / Avrum N. Pollock and Stephen M. Henesch -- Postoperative spinal imaging / Ashwini D. Sharan, Hana Choe, and Laura Snyder -- Imaging of the previously injured spinal cord / Steven Falcone -- Experimental therapies for spinal cord injury / Marion Murray -- Experimental techniques of spinal imaging / Eric D. Schwartz.
  • Offers information needed to maximize the potential of ultrasound in daily practice. Topics include nephrology, urology, the urogenital tract in the child, non-ultrasound imaging of the urogenital tract, oncological management of tumors of the urogenital tract, and more.
  • Evidence-based medicine: outcomes assessment -- Fundamental principles and clinical assessment -- Imaging -- Problem-based approach to the principles of spinal injury management -- Upper cervical injuries and their management -- Subaxial cervical spine injuries and their management -- Thoracolumbar spine injuries and their management -- Rehabilitation following spinal injury and late complications -- Emerging techniques and translational research
  • 1. Spine classification systems to spine disease severity measures : a paradigm shift -- 2. Method for identifying and evaluating spine severity measures -- 3. What makes a quality severity measure? -- 4. How the severity measures are displayed in this book -- 5. Spine disease severity measures -- 6. Spine trauma severity measures -- 7. Going beyond classification systems : new horizons for adolescent idiopathic scoliosis.
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  • Outcomes instruments that attempt to assess the function and quality of life in patients suffering from various spine conditions are on the increase. This book sets out to evaluate and summarize over 100 outcomes instruments for the spine and its associated diseases.
  • Radiobiology of radiosurgery / Jae Ho Kim and Stephen Brown -- Clinical spinal cord tolerance to radiosurgery / Simon S. Lo [and 10 others] -- Management of spinal cord toxicity / Samuel Ryu, Steve Brown, and Jae Ho Kim -- Histopathologic examination of spinal lesions after radiosurgery / Nathan T. Zwagerman [and 6 others] -- Stereotactic spine radiotherapy : image guidance and patient immobilization / Max Dahele and Ben Slotman -- Treatment planning for spine radiosurgery / David Schlesinger, K. Martin Richardson, Kelly M. Spencer, Brian Winey, and Jason Sheehan -- Quality assurance and treatment delivery / Fang-fang Yin, Zheng Chang, and Justus Adamson -- Contemporary devices for spinal radiosurgery / Christoph Fürweger [and 5 others] -- Imaging, target delineation, and dose prescription / Eric Chang, Omar Ragab, Sukhjeet Batth, Shelly Bian, and Lydia Nng -- Radiosurgery for the re-treatment of progressive spine metastases / Andrew A. Kanner and Benjamin W. Corn -- Clinical outcomes after spinal radiosurgery / Peter C. Gerszten and John C. Flickinger -- Clinical outcomes of pain and quality of life after spinal radiosurgery / Lily Angelov, Sam Chao, and John Suh -- Radiosurgery for spinal canal compromise and spinal cord compression / Richard A. Rammo, Ian Y. Lee, Jack P. Rock, and Samuel Ryu -- Postoperative radiosurgery and minimally invasive surgical techniques / Tobias A. Mattei [and 7 others] -- Radiosurgery and percutaneous cement augmentation / Michael Decuypere and Jason A. Weaver -- Treatment failure, complications, and their management / Nicolaus Andratschke and Matthias Guckenberger -- Patient evaluation and treatment selection for spinal canal compromise / Samuel Ryu and Mark Bilsky -- Radiosurgery for benign extramedullary tumors of the spine / Iris C. Gibbs, Navjot Chaudhary, Steven D. Chang, Robert L. Dodd, and John R. Adler, Jr -- Radiosurgical treatment of spinal chordomas / James P. Caruso, Mark H. Bilsky, Josh Yamada, and Ilya Laufer -- The role of radiosurgery in the treatment of primary malignant spine and spinal cord tumors / Moon-Jun Sohn, Dong-Joon Lee, and Hye-Ran Lee -- Radiosurgery for spinal cord arteriovenous malformations / Maziyar A. Kalani, Iris C. Gibbs, John R. Adler, Jr., and Steven D. Chang -- Multidisciplinary approach for the evaluation and treatment of metastatic spinal tumors / Ganesh M. Shankar, Kevin Oh, Kristina Shultz, and John H. Shin.
  • Spine secrets plus. 2nd ed. 2012
    2012 ClinicalKey
  • Spine surgery has increasingly become a surgical field of its own, with a distinct body of knowledge. While available textbooks cover the intricacies of spine surgery and provide extensive information on each pathology, these books are not geared towards the requirements of the novice and are insufficiently portable for the busy resident to carry while on rounds or on call. This easy-to-use book, written by acknowledged experts, is designed to meet such needs by providing essential information on spine pathology, diagnostic evaluation, surgical procedures, and other treatments. After an opening general section, degenerative spinal disease, pediatric spine conditions, spine trauma, spine tumors, infections, inflammatory disorders, and metabolic conditions are all discussed in more depth. Alongside description and evaluation of surgical options, important background information is included on pathology, presentation, diagnosis, and nonsurgical treatments. Potential complications of surgery are also carefully considered. Spine Surgery Basics will be an invaluable practical aid for all who are embarking on a career in spinal surgery or require a ready reference that can be consulted during everyday clinical practice.
  • Fully revises second edition, keeping its focus on presenting surgical techniques of both common and uncommon procedures written by prestigious contributing specialists, and maintaining its approach of demonstrating step-by-step surgical instructions, including tips, pearls, pitfalls and "rescues", making this new edition an even more invaluable resource and guide for all those operating on the spine. Includes new chapters on minimally invasive exposure and fixation techniques of posterior spine, percutaneous cement augmentation techniques (including vertebroplasty and kyphoplasty), and bone grafting and reconstruction.
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  • Make the best use of the latest techniques with step-by-step guidance from Spine Surgery. Edited by Edward C. Benzel, this best-selling neurosurgery reference explores the full spectrum of surgical techniques used in spine surgery and delivers the comprehensive, cutting-edge guidance you need to achieve successful outcomes. Glean essential, up-to-date information in one comprehensive reference that explores the full spectrum of techniques used in spine surgery. Hone your surgical skills and technique with intraoperative videos and more than 800 outstanding illustrations demonstrating each technique step by step.
  • Spine surgery. 2nd ed. 2012
    Section I: Cervical Spine. Closed Cervical Skeletal Tong Placement and Reduction Techniques ; Halo Placement in the Pediatric and Adult Patient ; Anterior Odontoid Resection: The Transoral Approach ; Odontoid Screw Fixation ; Anterior C1-C2 Arthrodesis: Lateral Approach of Barbour and Whitesides ; Anterior Cervical Corpectomy/Diskectomy ; Anterior Resection of Ossification of the Posterior Longitudinal Ligament ; Anterior Cervical Disk Arthroplasty; Occipital-Cervical Fusion ; C2 Translaminar Screw Fixation ; Posterior C1-C2 Fusion: Harms and Magerl Techniques ; Cervical Spine: Lateral Mass Screw Fixation ; Cervical Pedicle Screw Fixation ; Posterior Cervical Osteotomy Techniques ; Posterior Cervical Laminoplasty. -- Section II: Thoracic Spine. Anterior Thoracic Diskectomy and Corpectomy ; Anterior Thoracolumbar Spinal Fusion via Open Approach for Idiopathic Scoliosis ; Operative Management of Scheuermann's Kyphosis ; Resection of Intradural Intramedullary or Extramedullary Spinal Tumors ; Endoscopic Thoracic Diskectomy ; VEPTR Opening Wedge Thoracostomy for Congenital Spinal Deformities ; Posterior Thoracolumbar Fusion Techniques for Adolescent Idiopathic Scoliosis ; Thoracoplasty for Rib Deformity ; Complete Vertebral Resection for Primary Spinal Tumors. -- Section III: Lumbar Spine. Sacropelvic Fixation ; Posterior Far Lateral Disk Herniation ; The Lateral Extracavitary Approach for Vertebrectomy ; Osteotomy Techniques (Smith-Petersen and Pedicle Subtraction) for Fixed Sagittal Imbalance ; Spondylolysis Repair ; Surgical Treatment of High-Grade Spondylolisthesis ; Interspinous Process Motion-Sparing Implant ; Anterior Lumbar Interbody Fusion ; Transforaminal Lumbar Interbody Fusion ; Transpsoas Approach for Thoracolumbar Interbody Fusion ; Lumbar Total Disk Arthroplasty ; Kyphoplasty ; Minimally Invasive Exposure Techniques of the Lumbar Spine ; Hemivertebrae Resection ; Lumbar Internal Laminectomy ; Minimally Invasive Presacral Retroperitoneal Approach for Lumbosacral Axial Instrumentation.
  • Spine technology handbook 2006
    2006 MyiLibrary
    Over the past decade, there has been rapid growth in bioengineering applications in the field of spine implants. This book explains the technical foundation for understanding and expanding the field of spine implants, reviews the major established technologies related to spine implants, and provides reference material for developing and commercializing new spine implants. The editors, who have a track record of collaboration and editing technical books, provide a unified approach to this topic in the most comprehensive and useful book to date. Related website provides the latest information on spine technology including articles and research papers on the latest technology and development. Major technologies reviewed include devices used for fusion (screws, plates, rods, and cages), disc repair and augmentation, total disc replacement, and vertebral body repair and augmentation. Technology landscape, review of published/public domain data currently available, and safety and efficacy of technology discussed in detail.
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  • Spiritual care in a hospital setting : a problem -- Aspects of quality assurance in health care -- Worldview in health care -- The spiritual caregivers worldview -- Legitimacy and position of spiritual care in health care -- Goals and tasks of spiritual care -- Determinants of spiritual care -- Synopsis and recommendations.
  • Towards a joint paradigm reconciling faith and research / Thomas St. James O'Connor and Elizabeth Meakes -- A critical dialogue between theology and psychology / Paul J. Rennick -- Assessing plurality in spirituality definitions / Pam McCarroll, Thomas St. James O'Connor, and Elizabeth Meakes -- Spirituality and family medicine / Cheryl Levitt -- Congregational life after abuse / Carol Penner -- Islamic spiritual care in a health care setting / Nazila Isgandarova -- Communication in spiritual care among people with dementia / Ellen Bouchard Ryan, Lori Schindel-Martin, and Amanda Beaman -- Spirituality and addiction / Lori Edey -- Spirituality in occupational therapy / Sue Baptiste -- Using a labyrinth in spiritual care / Ingrid Bloos -- A wholistic approach to healing : an individual, family, and community model / Calvin Morrisseau -- Old religion, new spirituality, and health care / Carlton F. Brown -- God-talk in the spiritual care of palliative patients / Colleen Lashmar -- Measuring and assessing suffering in arthritic patients / Beverley Clarke ... [et al.] -- Psychosomatics and the spiritual entities of the human psyche / Marie-Line Morin -- Life-threatening illness : a dangerous opportunity / Beverly Musgrave -- The neurobiology of consciousness and spiritual transformation in healing / Stephen M. Sagar.
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  • Spirituality in hospice palliative care 2013
    ebrary, Limited to 3 simultaneous users
    This groundbreaking book addresses the spiritual aspect of hospice care for those who do not fit easily within traditional religious beliefs and categories. A companion volume to Religious Understandings of a Good Death in Hospice Palliative Care, this work also advocates for renewed attention to the spiritual, the often overlooked element of hospice care. Drawing on data from clinical case studies, new sociological research, and the perspectives of agnostics, atheists, those who emphasize the spiritual rather than institutional dimensions of a traditional religion, and the rapidly growing cohort of those who describe themselves as spiritual-but-not-religious, the contributors to this volume interpret the shift from predominantly Christian-based pastoral services to a new approach to "the spiritual" shaped by the increasing diversity of Western societies and new understandings of the nature of secular society. How do we use it in a way that enables caregivers to assist patients? Clinicians and policy makers will appreciate the book's practical recommendations regarding staff roles, training, and resource allocation. General readers will be moved by the persuasive call for greater religious and spiritual literacy at every level of health care in order to respond to the full spectrum of human needs in life and in death. -- Publisher
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    "Since the publication of the first edition of Spirituality in Patient Care in 2002, the book has earned a reputation as the authoritative introduction to the subject for health professionals interested in identifying and addressing the spiritual needs of patients. The body of research on religion, spirituality, and health continues to grow at a dramatic rate, creating an urgent need for a new edition of this landmark work. In this, the third edition, Harold G. Koenig, M.D., updates every chapter by incorporating the newest research and introducing sensible ways of translating that research into caring for patients. Like previous editions, this new one addresses the whys, hows, whens, and whats of patient-centered integration of spirituality into patient care so that health professionals, including physicians in primary care and the medical and surgical specialties, can utilize this information in clinical practice. Whole chapters are also included offering profession-specific information for nurses, clergy, mental health professionals, social workers, and occupational and physical therapists. Other chapters address topics like culturally and spiritually sensitive care for each major religious group, potential limitations or barriers to application, and even what may happen when research on spirituality and health is misapplied. Throughout these chapters, readers will find new case histories and clinical examples on how to integrate spirituality into patient care depending on their particular circumstances. A ten-session model course curriculum on spirituality and health care for medical students and residents is also provided, with suggestions on how to adapt it for nursing, social work, physical and occupational therapy, and mental health training programs. For more than ten years Spirituality in Patient Care has offered sound guidance to anyone wishing to do more than simply treat their patients' physical symptoms. Treating the whole patient often requires becoming something more than just a skilled technician. With this new edition, Dr. Koenig once again shows the way for any health professional seeking to bridge this gap and help patients regain their lives by finding hope, meaning, and healing."--Provided by publisher.
  • The spiritual foundation: awareness and context for people's lives today / Peter Gilbert -- Values-based practice: help and healing within a shared theology of diversity / Bill (K.W.M.) Fulford and Kim Woodbridge -- Spirituality and mental health across cultures / Suman Fernando -- Loss and grief: spiritual aspects / Neil Thompson -- Through a glass darkly: looking for my own reflection / Sarah Carr -- A journey - with faith: complex travels with Islam through the mental health system / Mariyam Maule ... [et al.] -- Connecting past and present: a survivor reflects on spirituality and mental health / Vicky Nicholls -- Who am I?: the search for spirituality in dementia: a family carer's perspective / Barbara Pointon -- A chaplain's own story / Paul Chapple -- Keep up your spirits: run for your life! a view of running as a spiritual experience / Peter Gilbert -- Spiritual assessment: narratives and responses / Wendy Edwards and Peter Gilbert -- Spirituality and psychiatry: crossing the divide / Andrew Powell -- Spiritual competence: mental health and palliative care / Cameron Langlands, David Mitchell and Tom Gordon. Working with Qi (Chi) to help with mental health problems / Nigel Mills -- Spiritual practice day by day - conversations with those who know / Mary Ellen Coyte -- How different religious organizations can work constructively together / Azim Kidwai and Ali Jan Haider -- Organizational health: engaging the heart of the organization / Sarajane Aris and Peter Gilbert -- A plea for broad understanding: why mental health practitioners need to understand spiritual matters / Christopher MacKenna -- Promoting spiritual well-being in the workplace - training and support for staff / Frances Basset and Thurstine Basset -- Awakening the heart and soul: reflections from therapy / Brian Thorne -- Mental health care: the ultimate context for spiritual and pastoral formation / Julia Head and Mark Sutherland -- Researching spirituality and mental health - a perspective from the research / John Swinton -- Researching the soul: the Somerset Spirituality Project / John Foskett and Anne Roberts -- Concluding thoughts / Mary Ellen Coyte, Peter Gilbert and Vicky Nicholls.
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    Tuberculosis is a complex and ancient disease that, after many years of virtual disappearance in the developed world, is now making something of a comeback. Helen Bynum tracks the historical development of the disease and considers the challenges it presents to the modern world.
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    ch. 1. History and development of forensic medicine and pathology / Daniel J. Spitz -- ch. 2. Crime scene -- pt. 1. Bloodstain pattern interpretation / Herbert Leon MacDonell -- pt. 2. Biological evidence on the human body / Heather Miller Coyle, Carrl Ladd, Henry C. Lee -- pt. 3. Trace evidence / Richard E. Bisbing -- ch. 3. Time of death and changes after death -- pt. 1. Anatomical considerations / Joshua A. Perper -- pt. 2. Chemical considerations / William Q. Sturner -- pt. 3. Forensic entomology / Neil H. Haskell -- pt. 4. Exhumation / Michael Mm. Baden -- ch. 4. Identification of human remains -- pt. 1. Diverse techniques / Daniel J. Spitz -- pt. 2. DNA / Lynne M. Helton -- ch. 5. Anthropology / William M. Bass -- ch. 6. Forensic odontology -- pt. 1. Bite mark identification / Richard R. Souviron -- pt. 2. Advanced techniques in dental identification and bite marks / David Sweet -- pt. 3. Advanced photographic techniques / Gregory S. Golden -- pt. 4. The use of digital analysis in bite mark identification / C. Michael Bowers, Raymond J. Johansen -- ch. 7. Sudden and unexpected death from natural causes in adults / Barbara A. Sampson, Vernard I. Adams, Charles S. Hirsch -- ch. 8. Investigation of deaths in childhood -- pt. 1. Feticide and neonaticide / Werner U. Spitz, Daniel J. Spitz -- pt. 2. The abused child and adolescent / Marvin S. Platt, Daniel J. Spitz, Werner U. Spitz -- pt. 3. The differential diagnosis of child abuse / Marvin S. Platt, Lisa Kohler -- ch. 9. Trauma and disease / Vernard I. Adams, Mark A. Flomenbaum, Charles S. Hirsch -- ch. 10. Blunt force injury / Werner U. Spitz -- ch. 11. Sharp force injury / Werner U. Spitz -- ch. 12. Injury by gunfire -- pt. 1. Gunshot wounds / Werner U. Spitz -- pt. 2. Shotgun wounds / Werner U. Spitz -- ch. 13. Thermal injuries / Werner U. Spitz -- ch. 14. Asphyxia / Werner U. Spitz -- ch. 15. Investigation of bodies in water / Daniel J. Spitz -- ch. 16. Electrical and lightning injuries / Edmund R. Donoghue, Barry D. Lifschultz -- ch. 17. Road traffic victim / Werner U. Spitz -- ch. 18. Medicolegal investigation of mass disasters / Glenn N. Wagner, Richard C. Froede -- ch. 19. Trauma of the nervous system -- pt. 1. Forensic neuropathology / Vernon Armbrustmacher, Charles S. Hirsch -- pt. 2. Boxing injuries / Friedrich Unterharnscheidt, James M. Henry -- ch. 20. Microscopic forensic pathology / Joshua A. Perper -- ch. 21. Forensic aspects of radiology / B.G. Brogdon -- ch. 22. Investigation of deaths from drug abuse / Boyd G. Stephens -- ch. 23. Forensic aspects of alcohol / Werner U. Spitz -- ch. 24. The medicolegal autopsy report / Werner U. Spitz -- ch. 25. Selected procedures at autopsy / Werner U. Spitz.
  • Section I: Basic Principles, Diagnosis, and Non-surgical Management -- Spondylolisthesis: A Historical Perspective on Etiology, Diagnosis, and Treatment -- Anatomy and Biomechanics Relevant to Spondylolisthesis -- Pain Generators in Spondylolisthesis -- Clinical Evaluation of Pediatric Patients with Spondylolisthesis.-Clinical Evaluation of Adult Patients with Spondylolisthesis -- Imaging Techniques for the Diagnosis of Spondylolisthesis -- Classification of Spondylolisthesis -- Role of the Pelvis in the Diagnosis and Management of L5-S1 Spondylolisthesis.-Non-Operative Treatment of Spondylolisthesis -- Non-surgical Management of Spondylolisthesis in Children and Adolescents -- Non-surgical Management of Spondylolisthesis in Adults -- Section II: Surgical Techniques.-Surgical Techniques: Spondylolysis Repair.-Decompression and Spinal Fusion.-Surgical Techniques: Posterior Lumbar Interbody Fusion.-Anterior Lumbar Interbody Fusion (ALIF).-Minimally Invasive TLIF for Adult Spondylolisthesis.-Surgical Technique: Lateral Interbody Fusion for Adult Spondylolisthesis.-Pre-sacral Fusion for Adult Spondylolisthesis.-Surgical Techniques: Management of High-Grade Spondylolisthesis including Reduction Techniques.-Management of Spondyloptosis.-Management of Traumatic Spondylolisthesis: Cervical and Lumbar.-Spondylolisthesis Associated with Scoliosis.-Section III: Results of Treatment and Complications -- Results of Surgical Treatment of Adult Degenerative Spondylolisthesis -- Results of Surgical Treatment of Low Grade Adult Isthmic Spondylolisthesis.-Results of Surgical Treatment of Pediatric Spondylolysis and Spondylolisthesis.-Complications Associated with Surgical Treatment of Adult Spondylolisthesis.-Complications Associated with Surgical Treatment of Pediatric Spondylolisthesis -- Intraoperative Neuro-monitoring During Spondylolisthesis Surgery.-Value Considerations in the Surgical Management of Spondylolisthesis. Results of Surgical Treatment of Low Grade Adult Isthmic Spondylolisthesis.-Results of Surgical Treatment of Pediatric Spondylolysis and Spondylolisthesis.-Complications Associated with Surgical Treatment of Adult Spondylolisthesis.-Complications Associated with Surgical Treatment of Pediatric Spondylolisthesis -- Intraoperative Neuro-monitoring During Spondylolisthesis Surgery.-Value Considerations in the Surgical Management of Spondylolisthesis. Intraoperative Neuro-monitoring During Spondylolisthesis Surgery.-Value Considerations in the Surgical Management of Spondylolisthesis.
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    The macronutrients -- The micronutrients and water -- Digestion and absorption of the food nutrients -- Nutrient role in bioenergetics -- Macronutrient metabolism in exercise and training -- Measurement of energy in food and during physical activity -- Nutritional recommendations for the physically active person -- Nutritional considerations for intense training and sports competition -- Making wise choices in the nutrition marketplace -- Exercise thermoregulation, fluid balance, and rehydration -- Pharmacologic and chemical ergogenic aids evaluated -- Nutritional ergogenic aids evaluated -- Body composition assessment and sport-specific observations -- Energy balance, exercise, and weight control -- Disordered eating.
  • Georg Stuebinger verifies each of the 24 most common and deadliest cancer diseases worldwide including well-established and potential risk factors resp. important symptoms by using current literature and comprehensive scientific studies with a direct relation to the impact of various parameters of sports and exercise training such as training type, intensity, volume, duration and frequency complete with the corresponding effects. The impact of sports and exercise training as a potential therapy on reduced risk of cancer has been widely discussed in many scientific articles over the last few years, but is still widely unknown. In 2012, about 14 m cancer cases and 8.2 m cancer deaths appeared worldwide whereby cancer represents one of the most frequent causes of death accounting for approximately 13% with a continuously rising number.
  • Sudden cardiac death in athletes: scope of the problem and emergency response -- Cardiovascular screening of athletes: focused exam, electrocardiograms, and limited echocardiograms -- Echocardiography and advanced cardiac imaging in athletes -- Exercise training and prescription -- Role of genetic testing for sudden death predisposing heart conditions in athletes -- Shortness of breath -- Chest pain in the athlete: differential diagnosis, evaluation, and treatment -- The collapsed athlete -- Syncope/presyncope in the competitive athlete -- Electrophysiological approach to syncope and near-syncope in the athlete -- Heart murmurs -- Management of hypertension in athletes -- Hypertrophic cardiomyopathy -- Commotio cordis: practical aspects in sports -- Coronary artery anomalies and sports activities -- Participation in sports for the athlete with the Marfan syndrome -- Congenital heart disease: exercise and sports participation -- Athlete with a device: implantable cardioverter defibrillators and pacemakers -- Long QT syndrome and other channelopathies -- Cardiac effects of ergogenic aides and supplements -- Return-to-play decisions in athletes with cardiac conditions: guidelines and considerations.
  • This comprehensive reference textbook examines in detail physiological and pathophysiological aspects of the cardiovascular system and cardiovascular disease in the sporting population. In the first part of the book, the non-invasive and invasive diagnostic techniques employed in cardiology are systematically reviewed, with explanation of their indications and clinical utility. The second, more extensive part is devoted to clinical cardiology and covers the great majority of cardiological problems encountered among athletes and other sportsmen and -women. Syncope, cardiac arrhythmias, and sudden cardiac death are extensively addressed, and guidance is provided on sports practice for individuals with different forms of heart disease. Cardiologic rehabilitation is discussed, and attention is also paid to the legal implications of diagnosed or unsuspected cardiovascular diseases for sportspeople. Sports Cardiology will be an invaluable resource for trainee and experienced health care professionals, including in particular cardiologists and sports medicine physicians. It will provide the knowledge required in order to make critical decisions regarding eligibility, thereby preventing tragic events and especially sudden death - the most devastating occurrence in sport.
  • Sports dermatology 2006
  • Sports hernias are an increasingly recognized problem in athletics, presenting a challenge for team physicians and other health care providers regarding their diagnosis and management. Confusion is magnified by the various treatment methods that exist, both surgical and non-surgical. Sports Hernia and Athletic Pubalgia is the first text devoted solely to the topic of sports hernia and will examine its etiology and diagnosis, as well as how to differentiate it from other problems involving the athlete's hip area and other injuries it often correlates and interacts with, such as femoroacetabular impingement. It covers all current approaches to treatment, from open approaches to minimally invasive approaches, and discusses rehabilitation and return to play. Comprised of contributions from an international array of expert clinicians and thought leaders, this is the immediate authoritative book on the subject of sports hernias.
  • Preface -- Part I: Sports Injury Surveillance -- Sports Injury Surveillance in Japan (from Sports Safety Association) -- Sports Injury Surveillance in Japanese Junior and Senior High School Students -- Injury and Illness Surveillance among Olympic Athletes -- Part II: Concussion and Severe Head-Neck Injury -- Concussions in Junior Rugby Football Athletes and their Prevention -- Prevention of head and neck trauma in rugby -- Severe Head & Neck Injury and its Prevention in Judo -- Concussion and Severe Head-Neck Injury: An Approach for their Prevention in Rugby and Judo -- Part III: ACL Injury: Injury Mechanism, Prevention Programs and Their Usefulness -- Video analysis of ACL injuries in sports -- Video Analysis of ACL Injury Mechanisms Using a Model-Based Image-Matching Technique -- Injury Rate of Soccer Players and the Efficacy of the FIFA 11 + Program -- Biomechanical Studies on ACL Injury Risk Factor During Cutting; Utilizing the Point Cluster Technique -- Biomechanical Risk Factors and Prevention of Anterior Cruciate Ligament Injury -- Risk Factor Analysis of Female Soccer Tournament Players -- Prevention of Anterior Cruciate Ligament (ACL) Injury -- Anterior Cruciate Ligament Injury Prevention in Female Adolescents -- FIFA 11+ -- Injury Prevention in Amateur Football -- From Development to Worldwide Dissemination -- Influence of Changing Direction on the Center of Gravity and Knee Joint Angle in Rugby Players -- Anterior Cruciate Ligament Injury Prevention in Female Lacrosse Players Based on an Examination of Knee and Hip Joint Mechanics During Drop Vertical Jumps Performed While Holding a Lacrosse Stick -- ACL Injury Mechanism in Badminton: Survey of Injury Situation and Motion Analysis Study -- Part IV: ACL Injury: Post-Operative Rehabilitation, Recovery of Function and Tendon Regeneration -- Functional Hop Tests Contribute to Safe Return to Sports after Anterior Cruciate Ligament Reconstruction -- Biomechanical Adaptations in Subjects after Anterior Cruciate Ligament Reconstruction: Preventing Secondary Injury -- Morphology and Function of the Semitendinosus Muscle-Tendon Complex after Harvesting its Tendon for Anterior Cruciate Ligament Reconstruction -- Part V: Muscle Functions, Occurrence Mechanisms, and Program to Prevent Strain in the Hamstring Muscles -- Functional Differences among Hamstring Muscles in Hip Extension and Knee Flexion Exercises -- Anatomical and Functional Differences of Hamstrings -- Differences in Activation Patterns of the Hamstring Muscles during Sprinting -- The Relationship between Eccentric Exercise and Muscle Damage in Hamstring Muscles -- Risk factors and prevention of hamstring strain -- Part VI: Function in Arches of the Feet and Occurrence Mechanisms of Foot Disorders, Characteristics and Their Prevention -- Kinematics of the Foot and Ankle -- Biomechanical Analysis of the Effects of Footwear -- Risk Factors and Mechanisms of Fifth Metatarsal Stress Fracture -- Part VII: Lumbar Disorder and an Approach for Its Prevention -- Low Back Disorders Among Athletes and Its Prevention -- The Epidemiology of Low Back Disorders in Athletes -- The Prevention of Low Back Disorders in Divers -- Electromyographic Analysis of Deep Trunk Muscles During Sports Activities.
  • pt. 1. Sports injuries in youth : general aspects -- pt. 2. Injuries by anatomical location -- pt. 3. Common injuries in popular sports.
  • This introduction to sports injuries in children and adolescents is written in a user-friendly format and takes into account the fact that sports injuries in the pediatric population are not an easy topic for non-pediatric orthopedic surgeons, pediatricians, and non-pediatric radiologists. The book is divided into five chapters on musculoskeletal particularities in children, head and spine trauma, muscle strains and avulsion injuries, bone fractures, overuse injuries, and miscellanea. Each of these chapters comprises ten cases, and each case study includes up to four figures, a description of the clinical case, a review of the pathophysiology of the condition described in the case, and a final section on imaging findings. Sports Injuries in Children and Adolescents is a case-based book aimed at pediatricians, pediatric orthopedic surgeons, and radiologists.
  • Sports Injuries of the Foot is the go-to text for the management and treatment of foot injuries in athletes, demonstrating the current state-of-the-art techniques in assessment, testing and treatment. Organized anatomically beginning with the toes and working down the foot, it covers such common athletic injuries as turf toe, bunions, MTP instability, and midfoot and navicular fractures, all in the context of athletic activity. Attention is also given to special considerations for the adolescent and female athlete, with an eye toward return to play. Written by clinicians for clinicians, it will be an invaluable resource for orthopedists, podiatrists, team physicians, athletic trainers and primary care providers alike.
  • Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.
  • Sports knee surgery 2008
    Sect. I: Knee arthroscopy/meniscus procedures -- (Knee examination and imaging -- Knee arthroscopy-the basics -- Arthroscopic synovectomy -- Arthroscopic lysis of adhesions -- Arthroscopic meniscectomy -- Meniscal cyst and discoid meniscus -- Inside-out and outside-in meniscal repair -- All-inside meniscal repair -- Arthroscopically assisted meniscus transplantation) -- Sect. II: Articular cartilage procedures -- (Chondroplasty and microfracture -- Osteochondral autograft transplantation -- Autologous chondrocyte implantation -- Osteochondral allograft transplantation -- Osteochondritis dissecans -- Avascular necrosis and core decompression -- Opening wedge high tibial osteotomy -- Unicondylar knee arthroplasty) -- Sect. III: Knee ligament procedures -- (Single-bundle anterior cruciate ligament reconstruction -- Complex (double-bundle and revision) anterior cruciate ligament reconstruction -- Pediatric anterior cruciate ligament injuries -- Posterior cruciate ligament reconstruction -- Knee medial collateral ligament reconstruction -- Posterolateral corner reconstruction -- Multiple ligament injury) -- Sect. IV: Patellofmoral procedures -- (Acute and chronic patellar tendon ruptures -- Quadriceps tendon repair -- Arthroscopic lateral retinacular release -- Patellar tendionpathy -- Acute patella dislocation: medial patellofemoral ligament repair -- Patella fracture -- Proximal realignment: medal patellofemoral ligament reconstruction -- Distal realignment).
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  • Sports Medicine and Arthroscopic Surgery of the Foot and Ankle is an invaluable source of information for the sports medicine practitioner who performs foot and ankle surgery. All the common sports injuries of the foot and ankle that may require surgery are covered. The latest techniques, including arthroscopic approaches are highlighted. This unique text is designed to be a reference for all levels who want the best resource for their sports medicine foot and ankle patients who may require surgery.
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    Preparticipation physical evaluation / John L. Turner -- Sport psychology : psychological concepts and interventions / Chris Carr -- Tissue injury and healing / Sara Christensen Holz and Matthew Smuck -- The sports medicine approach to musculoskeletal medicine / Anthony Margherita -- Stretching and injury prevention / Vicki L. Voils and Nathan D. Prahlow -- Performance-enhancing sports supplements / Jeff Fields and John L. Turner -- Baseball injuries / Lance A. Rettig and Mark Ritter -- Racket sports injuries / Neeru Jayanthi and Jay V. Subbarao -- Golf injuries / Andrea L. Aagesen and Shashank J. Dave -- Swimming and diving injuries / Kevin M. Marberry and Dawn Schisler -- Road cycling injuries / Julia J. Walker and Shashank J. Dave -- Mountain biking injuries / Matthew Smuck -- Football injuries / Gerard A. Malanga, Jason Peter, and Dennis A. Bandemer, Jr. -- Soccer injuries / Elizabeth A. Grossart and Johnny G. Owens -- Running injuries / Michael Khazzam and Kevin M. Marberry -- Skiing and snowboarding injuries / Peter W. Bailey, Andrea J. Boon, and Eric J. Watson -- Gymnastics injuries / Grant Lloyd Jones, Todd C. Miller, and Donald C. LeMay -- Basketball injuries / Meenakshi Garg, Peter I. Sallay, and Patti Hunker -- Volleyball injuries / Nathan D. Prahlow -- Weight-training injuries / Jess D. Salinas, Jr. -- Women's musculoskeletal issues / Gary P. Chimes -- Musculoskeletal issues in the elderly / Nabiha N. Gill -- Health benefits of exercise / Angela T. Carbone and Albert Gunjan Singh.
  • Sideline physician / John H. Wilckens -- Preparticipation evaluation / Jay E. Noffsinger -- Team physician's bag / Scott D. Flinn and Elise T. Gordon -- Mass-participation event coverage / Scott W. Pyne -- Emergency planning for athletic events / Scott D. Flinn and Timothy Dwyer -- Victim or culprit: a pathoanatomic approach to the correct diagnosis / Anthony I. Beutler -- Physical examination of the wrist and hand / William A. Mitchell III and Ahmed A. Radwan -- Physical examination of the elbow / Thomas M. Howard, Joel L. Shaw and James Phillips -- Physical examination of the shoulder / Sean T. Mullendore -- Physical examination of the cervical and thoracic spine / Derek A. Woessner and Charles W. Webb -- Physical examination of the lumbar spine / Philip Ham and James D. Leiber -- Physical examination of the hip and pelvis / Peter H. Seidenberg and Marc A. Childress -- Physical examination of the knee / Nicholas A. Piantanida and Nicole T. Yedlinsky -- Physical examination of the foot and ankle / Karl B. Fields, Wesley R. Ibazebo and Ryan E. Modlinski -- General principles of fracture management / Howard J. McGowan -- Splinting and casting / Timothy J. Mazzola -- Radiographic lines and angles / Peter H. Seidenberg -- Wrist and hand fractures / Stephen J. Titus and W. Scott Deitche -- Soft-tissue injuries of the hand and wrist / Chad Asplund and Christopher D. Meyering -- Elbow injuries / Mark A. Slabaugh -- Injuries of the shoulder and arm -- pt. A. Soft-tissue shoulder injuries / Patrick St. Pierre and Rodney Gonzales -- pt. B. Shoulder fractures and clavicular joint injuries / Patrick St. Pierre and Rodney Gonzales -- Craniomaxillofacial injuries / Allyson S. Howe -- Cervical spine injuries / Barry P. Boden -- Thoracic and lumbar spine injuries / Charles W. Webb and Richard Geshel -- Pelvic pain in the athlete / Adam J. Farber, John H. Wilckens and Christopher G. Jarvis -- Knee injuries / Andrew T. McDonald and Lyndon B. Gross -- Lower leg injuries / Greg Dammann and Duane R. Hennion -- Ankle fractures / Shawn E. Kane -- Foot fractures / Kevin deWeber -- Foot and ankle soft-tissue injuries / Ahmed A. Radwan, Peter H. Seidenberg and Greg Dammann -- Pediatric and adolescent injuries -- pt. A. Treatment of common pediatric and adolescent conditions / Mark B. Stephens -- pt. B. Spondylolysis: a practical approach to an adolescent enigma / Francis G. O'Connor, Pierre A. d'Hemecourt and Melissa Nebzydoski -- Stress fractures / Christopher M. Prior and Jessica A. Pesce -- Principles of sports rehabilitation / Jennifer Reed and Jimmy D. Bowen -- Practical application of osteopathic manipulation in sports medicine / Lori A. Boyajian-O'Neill and Dennis A. Cardone -- Core stabilization / Daniel L. Munton, Geof D. Manzo and Elizabeth J. Caschetta -- Physical therapy modalities / Guy R. Majkowski and Norman W. Gill III -- Athletic taping / Raymond D. Chronister and Gregg Calhoon -- Proper indications and uses of orthopedic braces / Jeff C. Leggitt and Christopher G. Jarvis -- Exercise prescription / David D. Farnsworth and Michael Cannon -- Cardiovascular testing / David A. Djuric and Francis G. O'Connor -- Testing for maximal aerobic power / Patricia A., Deuster and Yuval Heled -- Exercise-induced asthma testing / Rochelle M. Nolte and Christopher J. Lettieri -- Gait analysis / Timothy L. Switaj and Francis G. O'Connor -- Concussion testing and management / Scott A. Playford -- Running shoes: assessment and selection / Charles W. Webb and Marc A. Childress -- Compartment syndrome testing / Brandon D. Larkin and Janiece N. Stewart -- Electrodiagnostic testing / Jimmy D. Bowen -- Therapeutic and diagnostic injections and aspirations / Thomas M. Howard and Leslie H. Rassner -- Ergogenic aids / Jeffrey I. Levy [and others] -- Evidence-based regenerative injection therapy (prolotherapy) in sports medicine / K. Dean Reeves, Bradley D. Fullerton and Gaston Topol -- Team physician consensus statement -- Sports and physical activity in youth / Bernard Purcell and Mark B. Stephens -- Exercise prescription for pregnant patients / Pamela M. Williams and Michael Barron -- Exercise prescription for geriatric patients / Brian K. Unwin.
  • Sports medicine surgery 2010
  • "Many sports nutrition professionals are challenged by their lack of knowledge of both the functional limitations and the required alterations to training of the athlete with an impairment. In cases where the impairment results in minimal differences in the physiological basis of exercise, sports nutrition principles are easily transferable. However, other impairments such as spinal cord injuries, spina bifida, and cerebral palsy require a very individualized approach to estimations of energy expenditure and carbohydrate and fluid requirements. 'Sports Nutrition for Paralympic Athletes' provides information on the broad subcategories of all physical impairments, along with visual, hearing, and intellectual impairments. Specific areas such as body composition, supplements, and practical issues are discussed comprehensively. Case studies enhance and illustrate a direct and first-hand application to managing Paralympic athletes. Sports nutrition can be the difference in being competitive and making the podium. With the rapidly increasing Paralympic profile, this book will be required reading for professionals endeavoring to give their athletes the competitive edge. This book will challenge and stimulate current and future research in this area to improve the delivery of this intrinsic component of athlete preparation"--Provided by publisher.
  • Carbohydrate ingestion during exercise : effects on performance, training adaptations, and trainability of the gut / Jeukendrup, A.E.; McLaughlin, J. -- Altering endogenous carbohydrate availability to support training adaptations / Philp, A., Baar, K., Burke, L.M. -- Metabolic regulation of fat use during exercise and in recovery -- Spriet, L.L. -- Fat adaptation science : low-carbohydrate, high-fat diets to alter fuel utilization, and promote training adaptation / Hawley, J.A. -- Dietary protein to support muscle hypertrophy / van Loon, L.J.C., Gibala, M.J. -- Effect of protein, dairy components, and energy balance in optimizing body composition / Phillips, S.M., Zemel, M.B. -- Effect of cell hydration on metabolism / Lang, F. -- Practical nutritional recommendations for the athlete -- Maughan, R.J., Burke, L.M.
  • Introduction to sports nutrition: energy metabolism / Barry Braun and Benjamin F. Miller -- Utilization of carbohydrates in energy production / J. Andrew Doyle, Charilaos Papadopoulos, and Michael S. Green -- Utilization of fats in energy production / Serge P. von Duvillard ... [et al.] -- Utilization of proteins in energy metabolism / Mauro G. Di Pasquale -- Laboratory methods for determining energy expenditures of athletes / Robert G. McMurray and Kristin S. Ondrak -- Field assessment of physical activity and energy expenditure among athletes / Kelley K. Pettee, Catrine Tudor-Locke, and Barbara E. Ainsworth -- Influence of dietary fiber on body weight regulation / Daniel D. Gallaher -- Nutritional implications of sex and age differences in energy metabolism / A.C. Maher and Mark A. Tarnopolsky -- Body weight regulation and energy needs / Melina M. Manore and Janice L. Thompson.
  • Introduction to sports nutrition: fats and proteins / John J.B. Anderson -- Total fats, saturated fats, and cholesterol / Heather E. Rasmussen and Ji-Young Lee -- Medium-chain triglycerides / Wayne E. Billon -- Omega-3 and omega-6 fatty acids / Karina R. Lora and Nancy M. Lewis -- Conjugated linoleic acid / Celeste G. Koster and Martha A. Belury -- Octacosanol and wheat germ oil / Susan H. Mitmesser -- Protein: quantity and quality / Mark A. Tarnopolsky and Brian W. Timmons -- Whey, casein, and soy proteins / Brian S. Synder and Mark D. Haub -- Creatine / Richard B. Kreider -- Glucosamine and chondroitin sulfate / Catherine G.R. Jackson -- Carnitine / Sara Chelland Campbell and Robert J. Moffatt -- [Beta]-Hydroxy-[Beta]-Methylbutyrate / Steven L. Nissen -- Branched-chain amino acids / Michael Gleeson -- Glutamine / Satya S. Jonnalagadda -- Other individual amino acids / Neal F. Spruce and C. Alan Titchenal -- Recommended proportions of carbohydrates to fats to proteins in diets / Henry C. Lukaski. Introduction to sports nutrition: fats and proteins / John J.B. Anderson -- Total fats, saturated fats, and cholesterol / Heather E. Rasmussen and Ji-Young Lee -- Medium-chain triglycerides / Wayne E. Billon -- Omega-3 and omega-6 fatty acids / Karina R. Lora and Nancy M. Lewis -- Conjugated linoleic acid / Celeste G. Koster and Martha A. Belury -- Wheat germ oil and octacosanol / Susan H. Mitmesser -- Protein, quantity and quality / Mark A. Tarnopolsky and Brian W. Timmons -- Whey, casein, and soy proteins / Brian S. Synder and Mark D. Haub -- Creatine / Richard B. Kreider -- Glucosamine and chondroitin sulfate / Catherine G.R. Jackson -- Carnitine / Sara A. Chelland-Campbell and Robert J. Moffatt -- Beta-Hydroxy-Beta-Methylbutyrate / Steven L. Nissen -- Branched-chain amino acids / Michael Gleeson -- Glutamine / Satya S. Jonnalagadda -- Other individual amino acids / Neal F. Spruce and Alan Titchenal -- Recommended proportions of carbohydrates to fats to proteins in diets / Henry C. Lukaski.
  • Sports performance 2015
  • In the past decade, few issues at the intersection of medicine and sports have had as high a profile or have generated as much public interest as sports-related concussions. In recent years there has been a growing awareness and understanding that all concussions involve some level of injury to the brain and that athletes suspected of having a concussion should be removed from play for further evaluation (CDC, 2013; Halstead et al., 2010). Despite the increased attention, however, confusion and controversy persist in many areas, from how to define a concussion and how multiple concussions affect the vulnerability of athletes to future injury, to when it is safe for a player to return to sports and the effectiveness of protective devices and other interventions in reducing the incidence and severity of concussive injuries (Wilde et al., 2012). Parents worry about choosing sports that are safe for their children to play, about finding the equipment that can best protect their children, and about when, if a child does receive a concussion, it will be safe for him or her to return to play or if it might be time to quit a much-loved sport entirely. It is within this context that the Institute of Medicine (IOM) and National Research Council (NRC), in October 2012, convened the Committee on Sports-Related Concussions in Youth to review the science of sports-related concussions in youth from elementary school through young adulthood, including military personnel and their dependents, and to prepare a report on that topic based on that review. The committee was charged with reviewing the available literature on concussions within the context of developmental neurobiology, specifically relating to the causes of concussions, their relationship to impacts to the head or body during sports, the effectiveness of protective devices and equipment, screening for and diagnosis of concussions, their treatment and management, and their long-term consequences.
  • General Issues. Historical Overview of Familial Gastric Cancer / Giovanni Corso -- Frequency of Familial Gastric Cancer / Giovanni Corso, Daniele Marrelli -- The Family Cancer Database / Giovanni Corso, Daniele Marrelli, Franco Roviello -- Genetics and Epigenetics. The E-Cadherin Gene, Structure and Function / Francesco Graziano -- E-Cadherin Germline Mutations / Joana Carvalho, Hugo Pinheiro, Carla Oliveira -- Molecular Mechanisms of Hereditary Diffuse Gastric Cancer Initiation and Progression / Parry Guilford, Bostjan Humar -- Germline Missense Mutants in Hereditary Diffuse Gastric Cancer / Joana Figueiredo, Raquel Seruca -- Alternative Mechanisms to Germline CDH1 Mutations in Hereditary Diffuse Gastric Cancer / Hugo Pinheiro, Joana Carvalho, Carla Oliveira -- Beyond CDH1 Mutations: Causes of Hereditary Diffuse Gastric Cancer / Samantha Hansford B.Sc., David Huntsman, FRCPC -- Non-CDH1-Associated Familial Gastric Cancer and Epigenetics Factors / Marina Leite, Giovanni Corso, Sónia Sousa, Joana Carvalho -- Pathology. Hereditary Diffuse Gastric Cancer and Lobular Breast Carcinoma / Gisela Keller -- Pathology of Hereditary Gastric Cancer / Fátima Carneiro -- Management. Clinical Criteria for Familial Gastric Cancer Definition / Giulia De Falco, Alessandro Davide Videtta -- Prophylactic Total Gastrectomy in CDH1 Germline Mutation Carriers / Francesco Ferrara, Giovanni Corso, Franco Roviello -- Gastric Cancer in Other Inherited Syndromes / Giovanni Corso, Sérgia Velho -- Clinical Management of Familial Gastric Cancer / Giovanni Corso, Daniele Marrelli, Franco Roviello -- Appendix / Giovanni Corso
  • v. 1. Class 5: Isomerases -- v. 2. Class 6: Ligases -- v. 3. Class 4: Lyases I -- v. 4. Class 4: Lyases II -- v. 5. Class 4: Layases III -- v. 6. Class 3.4: Hydrolases I -- v. 7. Class 3.4: Hydrolases II -- v. 8. Class 3.4: Hydrolases III -- Index A: Synonym -- v. 9. Class 3.1: Hydrolases IV -- v. 10. Class 3.1: Hydrolases V -- v. 11. Class 3.1: Hydroclass VI -- v. 12. Class 3.2: Hydrolases VII -- v. 13. Class 3.2: Hydrolases VIII -- v. 14. Class 3.2-3.5: Hydrolases IX -- v. 15. Class 3.5-3.12: Hydrolases X -- v. 16. Class 1: Oxidoreductases I -- v. 17. Class 1: Oxidoreductases II -- v. 18. Class 1: Oxidoreductases III -- v. 19. Class 1: Oxidoreductases IV -- v. 20. Class 1: Oxidoreductases V. Class 1: Oxidoreductases VI -- v. 22. Class 1: Oxidoreductases VII -- v. 23. Class 1: Oxidoreductases VIII. -- v. 24. Class 1: Oxidoreductases IX -- v. 25. Class 1: Oxidoreductases X -- v. 26. Class 1: Oxidoreductases XI -- v. 27. Class 1: Oxidoreductases XII -- v. 28. Class 2: Transferases I -- v. 29. Class 2: Transferases II -- v. 30. Class 2: Transferases III -- v. 31. Class 2: Transferases IV -- v. 32. Class 2: Transferases V -- v. 33. Class 2: Transferases VI EC -- v. 34. Class 2: Transferases VI EC -- v. 35. Class 2: Transferases VIII -- v. 36. Class 2: Transferases IX -- v. 37. Class 2: Transferases X -- v. 38. Class 2: Transferases XI -- v. 39. Class 2: Transferases XII -- v. S1. Class 1: Oxidoreductases EC 1 -- v. S2. Class 2: Transferases EC 2.1-2.7.10 -- v. S3. Class 2: Transferases EC -- v. S4. Class 2: Transferases EC -- v. S5. Class 3: Hydrolases EC 3.1-3.4.21 -- v. S6. Class 3: Hydrolases EC3.4.22-3.13 -- v. S7. Class 4-6: Lyases, Isomerases, Ligases EC 4-6.
  • Springer series on biofilms v. 1-, 2007-
  • SPSS for dummies 2007
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  • SPSS for starters 2010
    Introduction -- One-Sample Continuous and Binary Data (t-Test, z-Test) (10 and 55 Patients) -- Paired Continuous Data (Paired-t, Wilcoxon) (10 Patients) -- Unpaired Continuous Data (Unpaired t-Tests, Mann-Whitney) (20 Patients) -- Linear Regression (20 Patients) -- Repeated Measures ANOVA, Friedman (10 Patients) -- Mixed Models (20 Patients) -- One-Way-ANOVA, Kruskall-Wallis (30 Patients) -- Trend Test for Continuous Data (30 Patients) -- Unpaired Binary Data (Chi-Square, Crosstabs) (55 Patients) -- Logistic Regression (55 Patients) -- Trend Tests for Binary Data (106 Patients) -- Paired Binary (McNemar Test) (139 General Practitioners) -- Multiple Paired Binary Data (Cochran's Q Test) (139 Patients) -- Cox Regression (60 Patients) -- Cox Regression with Time-dependent Variables (60 Patients) -- Validating Qualitative Diagnostic Tests (575 Patients) -- Validating Quantitative Diagnostic Tests (17 Patients) -- Reliability Assessment of Qualitative Diagnostic Tests (17 Patients) -- Reliability Assessment of Quantitative Diagnostic Tests (17 Patients) -- Final Remarks.
  • SQL cookbook 2006
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    Retrieving records -- Sorting query results -- Working with multiple tables -- Inserting, updating, deleting -- Metadata queries -- Working with strings -- Working with numbers -- Date arithmetic -- Date manipulation -- Working with ranges -- Advanced searching -- Reporting and warehousing -- Hierarchical queries -- Odds 'n' ends.
  • SQL for dummies. 6th ed. 2006
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    SQL fundamentals -- Joins, unions, and views -- Text handling -- Date handling -- Number crunching -- Online applications -- Organizing data -- Storing small amounts of data -- Locking and performance -- Reporting -- Users and administration -- Wider access.
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    Staff development and training are essential to ensure that libraries meet new challenges and fulfill their missions, especially in a constantly changing world where technological innovations directly impact information access. This new edition offers unique, state-of-the-art perspectives on important topics in staff training.
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    Structure and function of neurons -- Synaptic neurotransmission and the anatomically addressed nervous system -- Signal transduction and the chemically addressed nervous system -- Transporters and G protein-linked receptors as targets of psychopharmacological drug action -- Ion channels and enzymes as targets of psychopharmacological drug action -- Psychiatric genetics -- Circuits in psychopharmacology -- From circuits to symptoms in psychopharmacology -- Psychosis and schizophrenia -- Antipsychotic agents -- Mood disorders -- Antidepressants -- Mood stabilizers -- Anxiety disorders and anxiolytics -- Pain and the treatment of fibromyalgia and functional somatic syndromes -- Disorders of sleep and wakefulness and their treatment -- Attention deficit hyperactivity disorder and its treatment -- Disorders of reward, drug abuse, and their treatment.
  • v. 1. Pre-analytic publications and unpublished drafts -- v. 2. Studies on hysteria -- v. 3. Early analytic publications -- v. 4. The interpretation of dreams (1) -- v. 5. The interpretation of dreams (II) -- v. 6. The psychopathology of everyday life -- v. 7. A case of hysteria, Three essays on sexuality, and other works -- v. 8. Jokes and their relation to the unconscious -- v. 9. Jensen's G̀radiva' and other works -- v. 10. The cases of L̀ittle Hans' and the R̀at Man' -- v. 11. Five lectures on psycho-analysis, Leonardo and other works -- v. 12. Case history of Schreber, Papers on technique, and other works -- v. 13. Totem and taboo and other works -- v. 14. A history of the psycho-analytic movement, Papers on metapsychology, and other works -- v.15. Introductory lectures on psycho-analysis (1) -- v. 16. Introductory lectures on psycho-analysis (II) -- v. 17. An infantile neurosis and other works -- v. 18. Beyond the pleasure principles, Group psychology, and other works -- v. 19. The ego and the Id and other works -- v. 20. An autobiographical study, Inhibitions, symptoms and anxiety, Lay analysis, and other works -- v. 21. The future of an illusion, Civlilization and its discontents, and other works -- v. 22. New introductory lectures and other works -- v. 23. Moses and monotheism, An outline of psycho-analysis and other works -- v. 24. Indexes, Bibliography, etc.
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    v. 1. Suggested standards for homes for the aged and nursing homes -- v. 2. Methods of establishing and maintaining standards -- v. 3. Bridging the gap between existing practices and desirable goals in homes for the aged and nursing homes.
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    Consists of a photographic record and landscape architectural layout of 22 benches containing a collection of personal stories about medical education, treatment, and research at Stanford. These thematically arranged granite benches/planters tied to chronological highlights of the history of medicine in paving stones constitute the Discovery Walk. The story includes conversations with over 200 research and clinical faculty, as well as students, staff, and alumni from the Stanford Community. The project was commissioned by Dean Philip Pizzo in 2008 for the centennial of the medical school and was dedicated in the spring of 2012. The Project also includes the Foundation Walk, a chronology of the school since its founding in 1858, and the Landscape Plan which creates an entrance to the School of Medicine and connection to the broader campus.
  • Message from the Chairman -- Cerebrovascular neurosurgery and stroke -- Stroke research --Neural Stem Cell Program -- Saving neurons from stress (exogenous migratory therapy) -- Pediatric Neurosurgery -- Stanford Center for Children's Brain Tumors -- Functional neurosurgery (movement disorders, epilepsy and pain) -- Stanford Brain Tumor Center -- CyberKnife radiosurgery -- Brain tumor research (testing a vaccine against glioblastomas) -- Stanford Pituitary Center and Skull Base Tumor Program -- NeuroSpine Program -- Partnership for spinal cord injury and repair -- NeuroSpine research -- NeuroTrauma -- Community outreach programs -- Neurosurgery nurses -- Neurosurgery education and training -- Donors to Stanford Neurosurgery -- Recent Stanford Neurosurgery publications.
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    "This book had its genesis in the need created by my involvement with undergraduate teaching starting in the Fall of 1970 when I was a resident fellow and taught a course on sleep for the students in my dormitory. The course began to attract other students and because of this I decided to offer a formal presentation in Winter Quarter 1971 and I have offered a course on sleep annually up until Winter Quarter 2003. Sleep and Dreams was not offered in 2004 or 2005 but due to high student demand, we resurrected the course for the Winter Quarter 2006. Around 1980, the various handouts developed into a quasi-textbook and by the middle of the 90s, the first Stanford Sleep Book was born. The current volume is the 5th edition"--Acknowledgements.
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    Appendix at end includes list of presidents, 1959-2015, thank you letter from Amir Dan Rubin, list of gifts to the Medical Center, 1959-2008 ($4.3M); services to Stanford Hospital, 1983-2014; scholarships, 1971-May 2014 ($1M); volunteer hours (over 3 million); and copy of the Auxiliary stationery, 1929.
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  • This book follows Starting to Read ECGs: The Basics by the same authorship and provides the beginner in electrocardiogram (ECG) interpretation with a concise, practical and systematic guide to interpreting ECGs. The authors have included an introduction to the pediatric ECG and genetic cardiac conditions in attempt to deepen readers awareness of some of the broader clinical issues. Starting to Read ECGs: A Comprehensive Guide to Theory and Practice expands on some of the topics introduced in the first book, but offers a deeper perspective with more detailed background information and a variety of practical interpretation methods. It can be read as a standalone book for those who already possess some basic ECG knowledge or for those who have read the first book in the series and wish to consolidate and expand on what they have already read. The book uses numerous diagrams, tables and practical examples to reinforce learning and summarize information succinctly, and will be an essential resource for medical students, junior doctors, and other health care professionals involved in the recording and interpretation of ECGs who wish to build their knowledge and confidence.
  • Chapter 1: How to record a 12-lead ECG -- Physiology -- What is an ECG -- Patient positioning -- Electrode placement -- Attaching the cables -- The machine -- What to write on the ECG -- Summary of key points -- Quiz -- Chapter 2: ECG basics -- How does the 12-lead ECG work? -- ECG paper -- Details found on a standard 12-lead ECG -- 12-lead ECG leads -- The PQRST waveform -- Deflection -- Summary of key points -- Quiz -- Chapter 3: Quality issues pertaining to ECG recording -- Background -- Leads -- Calibration markers -- ECG Documentation -- Summary of key points -- Quiz -- Chapter 4: Principles of ECG analysis -- Background -- Basic quality control checks -- The rate -- The rhythm -- The P wave -- The PR interval -- The QRS complex -- The ST segment -- The T wave -- The QT interval -- Electrical axis -- Additional features -- The normal ECG and normal variants -- Summary of key points -- Quiz -- Chapter 5: Chamber abnormalities -- Physiology -- Atrial abnormality -- Ventricular abnormality -- Normal variants -- Summary of key points -- Quiz -- Chapter 6: Arrhythmias -- Background -- Ectopic beats -- Atrial arrhythmias -- Junctional arrhythmias -- Ventricular Arrhythmias -- Summary of key points -- Quiz -- Chapter 7: Conduction delay -- Background -- Bundle Branch Blocks -- Atrioventricular Blocks (AV Blocks) -- Sinoatrial blocks (SA blocks) -- Sick Sinus Syndrome (SSS) -- Summary of key points -- Quiz -- Chapter 8: Miscellaneous cardiac conditions -- Background -- Paced rhythms -- Types of permanent pacemaker (PPM) -- ECG identification of Pacemakers -- Pericarditis -- Long QT syndromes -- Summary of key points -- Quiz -- Chapter 9: Non cardiac conditions identifiable on the ECG -- Background -- Electrolyte imbalances -- Hypothermia -- Digoxin use -- Pulmonary Embolism (PE) -- Summary of key points -- Quiz -- Chapter 10: Acute Coronary Syndromes -- Background -- Atherosclerosis -- Modifiable and non-modifiable risk factors for CHD -- Angina -- Acute Coronary Syndromes (ACS) -- Evolution of STEMI -- Left Bundle Branch Block (LBBB) and chest pain -- Summary of key points -- Quiz.
  • "All known local tobacco control ordinances in the US that have one or more of the following provisions--clean indoor air, youth access, or restrictions on tobacco advertising and promotion."
  • "Achieving equity in health requires a commitment to monitoring health inequalities which, in turn, necessitates strong, equity-oriented health information systems. High-quality data and robust monitoring systems ensure that efforts can be targeted appropriately and that progress can be tracked. Countries must strengthen health information systems to generate better data and evidence to measure progress. Integral to the health inequality monitoring process is the task of reporting data in a meaningful way. This State of inequality report exemplifies effective reporting practices, featuring the topic of reproductive, maternal, newborn and child health. The report addresses the challenge of how to best communicate a large and complex body of data in a manner that is comprehensible, flexible and appealing to a wide readership. Foreword viii Feature stories provide an in-depth look at the state of inequality for selected indicators and highlight key observations in reproductive health interventions, maternal health interventions, care-seeking for sick children, childhood immunization, child malnutrition and child mortality. Perhaps most notable, however, is the innovative use of electronic visualization technology. Story-point dashboards, for instance, guide the reader through a succession of visuals where readers can use interactive tools to further explore, sort and filter the data. Similarly, interactive maps and tables engage readers in customizing how data are viewed. The report reveals that significant inequalities exist in low- and middle-income countries in the area of reproductive, maternal, newborn and child health. The good health of women, infants and children is essential for sustainable development, and there is still much work to be done. Discussions will increasingly call into question how efforts to improve reproductive, maternal, newborn and child health can achieve early and accelerated progress among those who are falling behind."--Pages viii-ix
  • To serve as a tool to help community planning groups (CPGs), health departments, and other stakeholders understand the issues behind Latino participation in HIV prevention community planning, as well as to increase Latino participation in the process.
  • State of the air 2014. 2014
    American Lung Association
    The State of the Air 2014 report looks at levels of ozone and particle pollution found in official monitoring sites across the United States in 2010, 2011, and 2012. The report uses the most current quality-assured nationwide data available for these analyses.
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    State of the art analytical comparability: a review / A.J. Chirino, A.R. Mire-Sluis -- Validation of peptide mapping with electrospray mass spectrometry for recombinant proteins of biopharmaceutical interest and its applications as an identity test and a characterization tool / Z. Wei ... [et al.] -- Analysis of protein therapeutics by capillary electrophoresis: applications and challenges / S. Ma -- Mass spectrometry and HPLC for carbohydrate analysis / J. Siemiatkoski, Y. Lyubarskaya -- Using nuclear magnetic resonance spectroscopy to characterize biologicals / D.I. Freedberg -- Infrared and raman spectroscopy characterization of biological products / V. Reipa -- Characterization of an immune response / S.J. Swanson -- Evaluation of standard and state of the art analytical technology - bioassays / S.R. Indelicato ... [et al.] -- Heterogeneity of recombinant antibodies: linking structure to function / R.J. Harris -- Quality control system to support comparability assessment for the renal bio-replacement therapy system / Z. Pitkin -- Characterization of gene therapy products and the impact of manufacturing changes on product comparability / S.L. Simek -- Characterization of allergen extracts / J.E. Slater -- Detection, measurement and characterization of unwanted antibodies induced by therapeutic biologicals / M. Wadhwa ... [et al.] -- De-immunization of therapeutic proteins by T-cell epitope modification / A.S. de Groot, P.M. Knopf, W. Martin -- Strategies for the preclinical and clinical characterization of immunogenicity / E. Koren ... [et al.]
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  • Scientific method : the language of statistical studies -- Experimentation : the foundation of scientific studies -- Numbers good and bad : how to judge the quality of data -- Samples and surveys : how numbers should be collected -- Descriptive statistics : the foundation of comparisons -- Inferential statistics : studies of differences -- Relational statistics : studies of relationships -- Explanatory statistics : studies of causality.
  • The core principles of statistical analysis are too easily forgotten in today's world of powerful computers and time-saving algorithms. This step-by-step primer takes researchers who lack the confidence to conduct their own analyses right back to basics, allowing them to scrutinize their own data through a series of rapidly executed reckonings on a simple pocket calculator. A range of easily navigable tutorials facilitate the reader's assimilation of the techniques, while a separate chapter on next generation Flash prepares them for future developments in the field. This practical volume also contains tips on how to deny hackers access to Flash internet sites. An ideal companion to the author's co-authored works on statistical analysis for Springer such as Statistics Applied to Clinical Trials, this monograph will help researchers understand the processes involved in interpreting clinical data, as well as being a necessary prerequisite to mastering more advanced statistical techniques. The principles of statistical analysis are easily forgotten in today's world of time-saving algorithms. This step-by-step primer takes researchers back to basics, enabling them to examine their own data through a series of sums on a simple pocket calculator.
  • "Human growth refers to changes in anthropometric measurements, such as fetal size parameters, height, weight, and body mass index. Development refers to changes in cognitive, social-emotional, locomotor, and other abilities. This book illustrates how statistical methods can be used to answer research questions in human growth and development. In addition to describing methods, it looks at how well a method addresses a specific research question and how to interpret and present the analytic results. Although the examples are drawn from human growth and development, the concepts and methods are applicable to studies of many other physical and psychological phenomena, such as lung function and depressive symptoms. Requiring introductory statistics knowledge, the book is intended for clinical researchers, epidemiologists, social scientists, statisticians, related researchers, and post-graduate students investigating human growth and development"--Provided by publisher.
  • Statistical analysis with Excel for dummies 2005
    books24x7, SUNet ID login required.
  • "The massive amount of nonstandard high-dimensional brain imaging data being generated is often difficult to analyze using current techniques. This challenge in brain image analysis requires new computational approaches and solutions. But none of the research papers or books in the field describe the quantitative techniques with detailed illustrations of actual imaging data and computer codes. Using MATLABʼ and case study data sets, Statistical and Computational Methods in Brain Image Analysis is the first book to explicitly explain how to perform statistical analysis on brain imaging data. The book focuses on methodological issues in analyzing structural brain imaging modalities such as MRI and DTI. Real imaging applications and examples elucidate the concepts and methods. In addition, most of the brain imaging data sets and MATLAB codes are available on the author's website. By supplying the data and codes, this book enables researchers to start their statistical analyses immediately. Also suitable for graduate students, it provides an understanding of the various statistical and computational methodologies used in the field as well as important and technically challenging topics."--Provided by publisher.
  • Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics link model -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response.
  • Introduction -- Two basic data mining methods for variable assessment -- CHAID-based data mining for paired-variable assessment -- The importance of straight data : simplicity and desirability for good model-building practice -- Symmetrizing ranked data : a statistical data mining method for improving the predictive power of data -- Principal component analysis : a statistical data mining method for many-variable assessment -- The correlation coefficient : its values range between plus/minus 1, or do they? -- Logistic regression : the workhorse of response modeling -- Ordinary regression : the workhorse of profit modeling -- Variable selection methods in regression : ignorable problem, notable solution -- CHAID for interpreting a logistic regression model -- The importance of the regression coefficient -- The average correlation : a statistical data mining measure for assessment of competing predictive models and the importance of the predictor variables -- CHAID for specifying a model with interaction variables -- Market segmentation classification modeling with logistic regression -- CHAID as a method for filling in missing values -- Identifying your best customers : descriptive, predictive, and look-alike profiling -- Assessment of marketing models -- Bootstrapping in marketing : a new approach for validating models -- Validating the logistic regression model : try bootstrapping -- Visualization of marketing modelsdata mining to uncover innards of a model -- The predictive contribution coefficient : a measure of predictive importance -- Regression modeling involves art, science, and poetry, too -- Genetic and statistic regression models : a comparison
  • Molecular genetics -- Formal genetics -- Genetic markers -- Data quality -- Genetic map distances -- Family studies -- Twin and adoption studies -- Model-based linkage analysis -- Model-free linkage analysis -- Quantitative traits -- Fundamental concepts of association analyses -- Association analysis in unrelated individuals -- Family-based association analysis -- Haplotypes in association analyses -- Genome-wide Association (GWA) studies.
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  • Introduction -- Accelerated testing -- Expiration dating period -- Stability designs -- Stability analysis with fixed batches -- Stability analysis with random batches -- Stability analysis with a mixed effects model -- Stability analysis with discrete responses -- Stability analysis with multiple components -- Stability analysis with frozen drug products -- Stability testing for dissolution -- Current issues and recent development.
  • Chapter 1 -- Background and Introduction; Chapter 2 -- Diagnostic Rating Scales; Chapter 3 -- Monotone Transformation Models; Chapter 4 -- Combination and Pooling of Biomarkers; Chapter 5 -- Bayesian ROC Methods; Chapter 6 -- Sequential Designs of ROC Experiments; Chapter 7 -- Multireader ROC Analysis; Chapter 8 -- Free-Response ROC Analysis; Chapter 9 -- Machine Learning and Predictive Modeling; Chapter 10 -- Summary and Challenges; Appendix: Notation List; Back Cover.
  • Apples or oranges? -- selection of the control group -- Who was left out? exclusions, refusals, and drop-outs -- Mountain or molehill? the clinical importance of the results -- What do the other witnesses say? corroborating vidence -- Do the pieces fit together? systematic overviews and meta-analysis -- What do all these numbers mean? -- Where is the evidence? searching for information.
  • "Data analysis is changing fast. Driven by a vast range of application domains and affordable tools, machine learning has become mainstream. Unsupervised data analysis, including cluster analysis, factor analysis, and low dimensionality mapping methods continually being updated, have reached new heights of achievement in the incredibly rich data world that we inhabit.Statistical Learning and Data Science is a work of reference in the rapidly evolving context of converging methodologies. It gathers contributions from some of the foundational thinkers in the different fields of data analysis to the major theoretical results in the domain. On the methodological front, the volume includes conformal prediction and frameworks for assessing confidence in outputs, together with attendant risk. It illustrates a wide range of applications, including semantics, credit risk, energy production, genomics, and ecology. The book also addresses issues of origin and evolutions in the unsupervised data analysis arena, and presents some approaches for time series, symbolic data, and functional data. Over the history of multidimensional data analysis, more and more complex data have become available for processing. Supervised machine learning, semi-supervised analysis approaches, and unsupervised data analysis, provide great capability for addressing the digital data deluge. Exploring the foundations and recent breakthroughs in the field, Statistical Learning and Data Science demonstrates how data analysis can improve personal and collective health and the well-being of our social, business, and physical environments. "-- Provided by publisher.
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    Discriminant analysis based on continuous and discrete variables -- Longitudinal data analysis with linear regression -- A kernal method used for the analysis of replicated micro-array experiments -- Kernel estimates of hazard functions for biomedical data sets -- Partially linear models -- Analysis of contingency tables -- Identifying coexpressed genes -- Bootstrap methods for testing interactions in GAMs -- Survival trees -- A semiparametric reference curves estimation -- Survival analysis -- Ozone pollution forecasting -- Nonparametric functional chemometric analysis -- Variable selection in principal component analysis -- Spatial statistics -- Functional data analysis -- Analysis of failure time with microearthquakes applications -- Landcover prediction -- The application of fuzzy clustering to satellite images data.
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  • Introduction / Jana Asher -- The statistics of genocide / Mary W. Gray and Sharon Marek -- Why estimate direct and indirect casualties from war? The rule of proportionality and casualty estimates / Beth O. Daponte -- Statistical thinking and data analysis : enhancing human rights work / Jorge L. Romeu -- Hidden in plain sight : X.X. burials and the desaparecidos in the Department of Guatemala, 1977-1986 / Clyde Collins Snow, Fredy Armando Peccerelli, José Samuel Susanávar, Alan G. Robinson, and Jose Maria Najera Ochoa -- The demography of conflict-related mortality in Timor-Leste (1974-1999) : reflections on empirical quantitative measurement of civilian killings, disappearances, and famine-related deaths / Romesh Silva and Patrick Ball -- Afghan refugee camp surveys in Pakistan, 2002 / James Bell, David Nolle, Ruth Citrin and Fritz Scheuren -- Metagora : an experiment in the measurement of democratic governance / Jan Robert Suesser and R. Suarez de Miguel -- Human rights of statisticians and statistics of human rights : early history of the American Statistical Association's Committee on Scientific Freedom and Human Rights / Thomas B. Jabine and Douglas A. Samuelson -- Obtaining evidence for the International Criminal Court using data and quantitative analysis / Herbert F. Spirer and William Seltzer -- New issues in human rights statistics / David L. Banks and Yasmin H. Said -- Statistics and the Millennium Development Goals / David J. Fitch, Paul Wassenich, Paul Fields, Fritz Scheuren, and Jana Asher -- Using population data systems to target vulnerable population subgroups and individuals : issues and incidents / William Seltzer and Margo Anderson.
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  • Univariate Data -- Bi- and Multivariate Data -- Related Topics -- Complex Examples -- Appendices.
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  • Part I. Basic statistics -- 1. Experimental statistics for biological sciences / Heejung Bang and Marie Davidian -- 2. Nonparametric methods for molecular biology / Knut M. Wittkowski and Tingting Song -- 3. Basics of Bayesian methods / Sujit K. Ghosh -- 4. The Bayesian t-test and beyond / Mithat Gönen -- -- Part II. Designs and methods for molecular biology -- 5. Sample size and power calculation for molecular biology studies / Sin-Ho Jung -- 6. Designs for linkage analysis and association studies of complex diseases / Yuehua Cui ... [et al.] -- 7. Introduction to epigenomics and epigenome-wide analysis / Melissa J. Fazzari and John M. Greally -- 8. Exploration, visualization, and preprocessing of high-dimensional data / Zhijin Wu and Zhiqiang Wu -- -- Part III . Statistical methods for microarray data -- 9. Introduction to the statistical analysis of two-color microarray data / Martina Bremer, Edward Himelblau, and Andreas Madlung -- 10. Building networks with microarray data / Bradley M. Broom ... [et al.] -- Part IV. Advanced or specialized methods for molecular biology -- 11. Support vector machines for classification: a statistical portrait / Yoonkyung Lee -- 12. An overview of clustering applied to molecular biology / Rebecca Nugent and Marina Meila -- 13. Hidden Markov model and its applications in motif findings / Jing Wu and Jun Xie -- 14. Dimension reduction for high-dimensional data / Lexin Li -- 15. Introduction to the development and validation of predictive biomarker models from high-throughput data sets / Xutao Deng and Fabien Campagne -- 16. Multi-gene expression-based statistical approaches to predicting -- patients' clinical outcomes and responses / Feng Cheng, Sang-Hoon Cho, and Jae K. Lee -- 17. Two-stage testing strategies for genome-wide association studies in family-based designs / Amy Murphy, Scott T. Weiss, and Christoph Lange -- 18. Statistical methods for proteomics / Klaus Jung -- -- Part V. Meta-analysis for high-dimensional data -- 19. Statistical methods for integrating multiple types of high-throughput data / Yang Xie and Chul Ahn -- 20. A Bayesian hierarchical model for high-dimensional meta-analysis / Fei Liu -- 21. Methods for combining multiple genome-wide linkage studies / Trecia A. Kippola and Stephanie A. Santorico -- -- Part VI. Other practical information -- 22. Improved reporting of statistical design and analysis: guidelines, education, and editorial policies / Madhu Mazumdar, Samprit Banerjee, and Heather L. Van Epps -- 23. Stata companion / Jennifer Sousa Brennan.
  • Markov models in molecular evolution / Nicolas Galtier, Olivier Gascuel, and Alain Jean-Marie -- Introduction to applications of the likelihood function in molecular evolution / Jutta Buschbom and Arndt von Haeseler -- Introduction to Markov chain Monte Carlo methods in molecular evolution / Bret Larget -- Population genetics of molecular evolution / Carlos D. Bustamante -- Maximum likelilhood methods for detecting adaptive protein evolution / Joseph P. Bielawski and Ziheng Yang -- HyPhy: hypothesis testing using phylogenies / Sergei L. Kosakovsky Pond and Spencer V. Muse -- Bayesian analysis of molecular evolution using MrBayes / John P. Huelsenbeck and Fredrik Ronquist -- Estimation of divergence times from molecular sequence data / Jeffrey L. Thorne and Hirohisa Kishino -- Markov models of protein sequence evolution / Matthew W. Dimmic -- Models of microsatellite evolution / Peter Calabrese and Raazesh Sainudiin -- Genome rearrangement / Rick Durrett -- Phylogenetic hidden Markov models / Adam Siepel and David Haussler -- The evolutionary causes and consequences of base composition variation / Gilean A.T. McVean -- Statistical alignment: recent progress, new applications, and challenges / Gerton Lunter ... [et al.] -- Estimating substitution matrices / Von Bing Yap and Terry Speed -- Posterior mapping and posterior predictive distributions / Jonathan P. Bollback -- Assessing the uncertainty in phylogenetic inference / Hidetoshi Shimodaira and Masami Hasegawa.
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    Simple linear regression -- Multiple linear regression -- Simple logistic regression -- Multiple logistic regression -- Introduction to survival analysis -- Hazard regression analysis -- Introduction to poisson regression : inferences on morbidity and mortality rates -- Multiple poisson regression -- Fixed effects analysis of variance -- Repeated-measures analysis of variance.
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    Let's get started: preliminaries and a SAS quick start -- Reading, combining, and managing data for later analysis -- Using SAS procedures -- Complex table construction and output control -- Basic models in SAS -- Producing statistical graphics in SAS -- Traditional SAS graphics -- Formatting variables, recoding variables, and writing programs -- Programming in a DATA step -- Macro programming -- Programming with matrices and vectors.
  • "While biomedical researchers may be able to follow instructions in the manuals accompanying the statistical software packages, they do not always have sufficient knowledge to choose the appropriate statistical methods and correctly interpret their results. Statistical Thinking in Epidemiology examines common methodological and statistical problems in the use of correlation and regression in medical and epidemiological research: mathematical coupling, regression to the mean, collinearity, the reversal paradox, and statistical interaction. Statistical Thinking in Epidemiology is about thinking statistically when looking at problems in epidemiology. The authors focus on several methods and look at them in detail: specific examples in epidemiology illustrate how different model specifications can imply different causal relationships amongst variables, and model interpretation is undertaken with appropriate consideration of the context of implicit or explicit causal relationships. This book is intended for applied statisticians and epidemiologists, but can also be very useful for clinical and applied health researchers who want to have a better understanding of statistical thinking. Throughout the book, statistical software packages R and Stata are used for general statistical modeling, and Amos and Mplus are used for structural equation modeling"--Provided by publisher.
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    Data display and summary -- Summary statistics for quantitative data -- Summary statistics for binary data -- Populations and samples -- Statements of probability and confidence intervals -- P-values, power, type I and type II errors -- The t tests -- The [chi]² tests -- Diagnostic tests -- Rank score tests -- Correlation and regression -- Survival analysis -- Study design and choosing a statistical test -- Use of computer software.
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  • Statistics in a nutshell 2008
    ProQuest Safari
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    v.1. Basic concepts and applications ; v.2 Advanced concepts and applications.
  • Planning studies: from design to publication -- Planning analysis: what do I do with my data? -- Probability and relative frequency -- Distribution -- Descriptive statistics -- Finding probabilities -- Confidence intervals -- Hypothesis testing: concept and practice -- Tests on categorical data -- Risks, odds, and ROC curves -- Tests on ranked data -- Tests on means of continuous data -- Multi-factor ANOVA and ANCOVA -- Tests on variability and distributions -- Managing results of analysis -- Equivalence testing -- Bayesian statistics -- Sample size estimation and meta-analysis -- Modeling concepts and methods -- Clinical decisions based on models -- Regression and correlation -- Multiple and curvilinear regression -- Survival, logistic regression, and cox regression -- Sequential analysis and time series -- Epidemiology -- Measuring association and agreement -- Questionnaires and surveys -- Methods you might meet, but not every day.
  • "Statistical investigation into technology not only provides a better understanding of the intrinsic features of the technology (analysis), but also leads to an improved design of the technology (synthesis). Physical principles and mathematical procedures of medical imaging technologies have been extensively studied during past decades. However, less work has been done on their statistical aspect. Filling this gap, this book provides a theoretical framework for statistical investigation into medical technologies. Rather than offer detailed descriptions of statistics of basic imaging protocols of x-ray CT and MRI, the book presents a method to conduct similar statistical investigations into more complicated imaging protocols"--Provided by publisher.
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    Introduction -- Examining univariate distributions -- Measures of location, spread, and skewness -- Re-expressing variables -- Exploring relationships between two variables -- Simple linear regression -- Probability fundamentals -- Theoretical probability models -- The role of sampling in inferential statistics -- Inferences involving the mean of a single population when s is known -- Inferences involving the mean when s is not known: one- and two-sample designs -- One-way analysis of variance -- Two-way analysis of variance -- Correlation and simple regression as inferential techniques -- An introduction to multiple regression -- Nonparametric methods.
  • History of status epilepticus / Peter W. Kaplan -- Types of status epilepticus: definitions and classification / Frank W. Drislane -- Differential diagnosis of status epilepticus; pseudostatus epilepticus / Barbara A. Dworetzky, Edward B. Bromfield -- The epidemiology of status epilepticus / Elizabeth J. Waterhouse -- The electroencephalogram in status epilepticus / Susan T. Herman -- Generalized convulsive status epilepticus: causes, systemic manifestations, and consequences / Bernard S. Chang -- Focal status epilepticus / Donald L. Schomer -- The Cellular physiology of status epilepticus / Omotola Hope, Hal Blumenfeld -- Cellular damage and the neuropathology of status epilepticus / Nathan B. Fountain -- Clinical presentations of nonconvulsive status epilepticus / Peter W. Kaplan -- Cognitive manifestations of status epilepticus: ictal aphasia, amnesia, and psychosis / Michael Benatar -- Nonconvulsive status epilepticus: morbidity and consequences / Frank W. Drislane -- Treatment of generalized convulsive status epilepticus / Tina Shih, Carl W. Bazil -- Treatment of refractory status epilepticus / Teresa L. Smith, Thomas P. Bleck -- Treatment of nonconvulsive status epilepticus / Frank W. Drislane -- Status epilepticus in children / James J. Riviello, Jr. -- Status epilepticus in neonates / John N. Gaitanis, James J. Riviello, Jr.
  • This report provides data on women's health status in the United States, beginning with a composite index of women's health that includes nine indicators covering chronic disease, sexual health, mental health, and physical health. It analyzes data on additional aspects of women's health, including behavioral measures such as smoking, exercise, and diet, and preventive health care measures such as mammograms, pap tests, and screenings for HIV. In addition, the report examines how women's health status has improved or declined in these areas in recent years. It also notes places where women's health status varies by race/ethnicity and age and examines the health status of those who identify as a sexual minority .
  • Obesity and diabetes develop as a complex result of genetic, metabolic and environmental factors and are characterized by increased lipogenesis and lipid accumulation in many tissues. Stearoyl-CoA desaturase (SCD) genes are a critical regulator of lipogenesis and catalyzes the synthesis of monounsaturated fatty acids (MUFA), mainly oleoyl- (18:1n9) and palmitoleoyl-CoA (16:1n7). These MUFAs are the major fatty acid substrates for the synthesis of triglycerides, cholesterol esters, wax esters and membrane phospholipids. There are 4 SCD isoforms (SCD1-4) in mice and two (hSCD1 and hSCD5) expressed in humans. At first glance, stearoyl-CoA desaturase enzyme would be considered a housekeeping enzyme because it synthesizes oleate a well-known fatty acid that is abundant in many dietary sources. However numerous studies have shown that SCD is a very highly regulated enzyme that features in so many physiological processes ranging from fat differentiation, carbohydrate and fat metabolism, inflammation and cancer. The editor's studies using stearoyl-CoA desaturase knockout (SCD1-/- ) mice and studies of other investigators using pharmacological approaches to reduce SCD1 expression in mouse tissues have all established that the expression of SCD1 gene isoform represents a key step in partitioning of lipids between storage and oxidation. High SCD expression favors fat storage leading to obesity while reduced SCD expression favors fat burning and leanness. Although these studies clearly illustrated that SCD1 expression is involved in the development of obesity and insulin resistance, questions remain in the elucidation of the mechanisms involved and role of SCD1. This book includes chapters by leading researchers on SCD Genes in the brain, heart, muscle, liver metabolism, Colitis, and more.
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  • Stedman's Medical dictionary 2006
    STAT!Ref, Limited to 7 simultaneous users
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    Anatomical illustrations -- Culture media -- Stains, dyes, and fixatives -- Greek alphabet -- Elements and symbols -- Units of measure for pathology -- Sample immunodiagnostic panels -- Common lab tests -- Drugs of abuse, toxicology, and therapeutic drug levels -- Sample reports -- Common terms by procedure --Classification by system including grades & stages.
  • Heart -- Neuro -- Musculoskeletal -- Kidney -- Eye -- Pancreas -- Hematology -- Skin.
  • Stem cell assays 2007
    Springer Protocols
    Derivation of human embryonic stem cells in xeno-free conditions / Mohan C. Vemuri ... [et al.] -- Feeder-layer free culture system for human embryonic stem cells / Michal Amit -- Digital imaging of stem cells by electron microscopy / A. Henry Sathananthan and Stefania A. Nottola -- A controlled-cooling protocol for cryopreservation of human and non-human primate embryonic stem cells / Carol B. Ware and Szczepan W. Baran -- Cell surface markers in human embryonic stem cells / Raj R. Rao, Alison Venable Johnson, and Steven L. Stice -- Generation of a monoclonal antibody library against human embryonic stem cells / Micha Drukker, Christina Muscat, and Irving L. Weissman -- Analytical methods for cancer stem cells / Vinagolu K. Rajasekhar -- Micro RNA profiling : an easy and rapid method to screen and characterize stem cell populations / Uma Lakshmipathy ... [et al.] -- Gene transfer via nucleofection into adult and embryonic stem cells / Uma Lakshmipathy, Shannon Buckley, and Catherine Verfaillie -- RNAi knockdown of transcription factor Pu.1 in the differentiation of mouse embryonic stem cells / Gang-Ming Zou, Meredith A. Thompson, and Mervin C. Yoder -- StemBase : a resource for the analysis of stem cell gene expression data / Christopher J. Porter ... [et al.] -- Isolation of stem cells from human umbilical cord blood / Nishanth P. Reddy, Mohan C. Vemuri, and Reddanna Pallu -- Ex vivo expansion of hematopoietic stem cells from human cord blood in serum-free conditions / Chao-Ling Yao and Shiaw-Min Hwang -- Hematopoietic colony-forming cell assays / Carla Pereira, Emer Clarke, and Jackie Damen -- Assays for alloreactive responses by PCR / Patrick Stordeur -- Immune properties of mesenchymal stem cells / Panagiota A. Sotiropoulou and Michael Papamichail -- Clinical grade expansion of human bone marrow mesenchymal stem cells / Panagiota A. Sotiropoulou, Sonia A. Perez, and Michael Papamichail -- Adenoviral transduction of mesenchymal stem cells / Pablo Bosch and Steven L. Stice -- Directed differentiation of human embryonic stem cells to dendritic cells / Maxim A. Vodyanik and Igor I. Sluvkin -- Insulin-producing cells from embryonic stem cells to dendritic cells / Maxim A. Vodyanik and Igor I. Slukvin -- Insulin-producing cells from embryonic stem cells experimental considerations / Enrique Roche ... [et al.] -- Efficient generation of dopamine neurons from human embryonic stem cells / Chang-Hwan Park and Sang-Hun Lee -- Isolation of oligodendroglial cells from cultured neural stem/progenitors / Frank Zeigler and Stephen G. Hall -- Differentiation of human embryonic stem cells toward the chondrogenic lineage / Wei Seong Toh ... [et al.] -- Cartilage tissue engineering : directed differentiation of embryonic stem cells in three-dimensional hydrogel culture / Nathaniel S. Hwang, Shyni Varghese, and Jennifer Elisseeff.
  • Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modeling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.
  • Part 1. Bone marrow-derived stem cells -- Part 2. Embryonic stem cells -- Part 3. Cancer stem cells.
  • "This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control"--Publisher's description.
  • Stem cell culture 2008
  • "Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward"--Provided by publisher.
  • Immunostaining of germline stem cells and the niche in Drosophila ovaries / Lichao Luo, Phing Chian Chai, and Yu Cai -- Genetic, immunofluorescence labeling, and in situ hybridization techniques in identification of stem cells in male and female germline niches / Shree Ram Singh ... [et al.] -- Visualization of adult stem cells within their niches using the Drosophila germline as a model system / Annekatrin König and Halyna R. Shcherbata -- Morphometric evaluation of the spermatogonial stem cell distribution and niche in vertebrates / Paulo Henrique Almeida Campos-Junior ... [et al.] -- In vitro construction of 2D and 3D simulations of the murine hematopoietic niche / Brahmananda Reddy Chitteti ... [et al.] -- Isolation of embryonic hematopoietic niche cells by flow cytometry and laser capture microdissection / Daisuke Sugiyama and Tatsuya Sasaki -- Isolation and enrichment of Stro-1 immunoselected mesenchymal stem cells from adult human bone marrow / Emma L. Williams, Kate White, and Richard O.C. Oreffo -- Primary marrow-derived stromal cells : isolation and manipulation / Aravind Ramakrishnan, Beverly Torok-Storb, and Manoj M. Pillai -- Detection in vitro and quantitative estimation of artificial microterritories which promote osteogenic differentiation and maturation of stromal stem cells / Igor A. Khlusov, Natalya M. Shevtsova, and Marina Yu. Khlusova -- Prospective isolation of viable, high ploidy megakaryocytes from adult murine bone marrow by fluorescence activated cell sorting / Shen Y. Heazlewood ... [et al.] -- Looking for the niche : substance delivery into the lateral ventricle of the brain : the osmotic minipump system / María Victoria Gómez Gaviro ... [et al.] -- Unbiased stereological method to assess proliferation throughout the subependymal zone / Ana Mendanha Falcão ... [et al.] -- Cardiac stem cell niche, MMP9, and culture and differentiation of embryonic stem cells / Paras Kumar Mishra ... [et al.] -- Human and murine skeletal muscle reserve cells / Rana Abou-Khalil, Fabien Le Grand, and Bénédicte Chazaud -- Modulation of the host skeletal muscle niche for donor satellite cell grafting / Luisa Boldrin and Jennifer E. Morgan -- Isolation of c-Kit+ human amniotic fluid stem cells from second trimester / Michela Pozzobon ... [et al.] -- Hypoxia and visualization of the stem cell niche / Ali Dalloul -- Detection and isolation of human disseminated tumor cells in the murine bone marrow stem cell niche / Yusuke Shiozawa, Russell S. Taichman, and Evan T. Keller -- Identification and separation of normal hematopoietic stem cells and leukemia stem cells from patients with acute myeloid leukemia / Van T. Hoang ... [et al.] -- Serial orthotopic transplantation of epithelial tumors in single-cell suspension / Heather A. McCauley and Géraldine Guasch -- Isolation and propagation of colon cancer stem cells / Pramudita R. Prasetyanti ... [et al.].
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    Foreword by Donald Kennedy -- Abbreviations -- The experiment that shook the world -- The cell -- How we get to how we are -- A brief history of embryonic stem cells -- Hunting adult stem cells -- Seven questions -- The future of medicine -- The great moral divide -- The consequences of politics -- Epilogue -- Notes -- Glossary -- Further reading -- Acknowledgments.
  • Ventricular remodeling in ischemic cardiomyopathy / Stefan Klotz and Daniel Burkhoff -- Myocardial regeneration: which cell and why / Elmostafa El Fahime and Jacques Tremblay -- Cardiac stem cells for myocardial regeneration / Bernardo Nadal-Ginard and Simón Méndez-Ferrer -- A historic recapitulation of myoblast transplantation / Daniel Skuk and Jacques Tremblay -- Myoblast cell transplantation preclinical studies / Doris A. Taylor and Harald Ott -- Skeletal myoblasts: the European experience / Philippe Menasche -- Skeletal myoblasts: the U. S. experience / Edward B. Diethrich -- Progenitor cells for cardiac regeneration / Ana Sánchez and Javier Garcia-Sancho -- Bone marrow derived stem cell for myocardial regeneration: preclinical experience / Bradley Martin and Mark Pittenger -- Bone marrow derived stem cell for myocardial regeneration: clinical experience, surgical delivery / Manual Galiñanes -- Autologous mononuclear bone marrow cell transplantation for myocardial infarction: the German experience / Michael Brehm, Tobias Zeus and Bodo E. Strauer -- Autologous mononuclear bone marrow cell transplantation for myocardial infarction: the Spanish experience / Francisco E. Avilés ... [et al.] -- Mobilizing bone marrow stem cells for myocardial repair after acute myocardial infarction / Steve Ellis and Oussama Wazni -- Percutaneous myoblast transplantation: steps in transplantation research / Nabil Dib -- A porcine model of myocardial infarction for evaluation of cell transplantation / Nabil Dib ... [et al.] -- Tissue engineering for myocardial regeneration / Ravi K. Birla -- The role of pet scan in stem cell therapy / Uchechukwa Sampson ... [et al.] -- The measurement of systolic function in the mammalian heart / Blasé Carabello -- Electrophysiological aspects of cell transplantation / Nicholas S. Peters, Nicolas A.F. Chronos and Fernando Tondato -- Regulatory considerations in manufacturing, product testing, and preclinical development of cellular products for cardiac repair / Ellen Areman, Kim Benton and Richard McFarland.
  • 1. Lysosomal diseases and therapeutic options: an overview / Eveline J. Langereis and Frits A. Wijburg -- 2. Alternative treatment options: enzyme replacement and small molecule therapies / James Edmond Wraith and Simon Jones -- 3. Hematopoietic cell transplantation in inborn errors of metabolism / Jaap J. Boelens, Paul Szaboles, and Rob Wynn -- 4. Leukodystrophies and lysosomal storage disorders / Maria L. Escolar and Mieke Aldenhoven -- 5. Hematopoietic stem cell gene therapy for lysosomal storage disorders: expected benefits and limitations / Alessandra Biffi and Ilaria Visigalli -- 6. Alternative future therapies for lysosomal storage diseases: embryonic stem cell- and induced pluripotent stem cell therapy / Arie Koen Braat, Paul J. Coffer, and Niels Geijsen -- 7. Concluding comments and future directions / Robert Wynn and Jaap Jan Boelens.
  • In vitro experimentation and research tools -- Tissue engineering and regenerative medicine.
  • Section I. Basic Aspects of Transplantation -- The Frontiers of Organ Transplantation and Cell Therapy / Rafael Matesanz -- Organ Transplantation in the 21th Century / Francisco Ortega -- Immunology and the Challenge of Transplantation / Rebeca Alonso Arias, Antonio López-Vázquez and Carlos López-Larrea -- Cellular Immunotolerance in the Transplant / Marcos Lóez-Hoyos, David San Segundo and Manuel Arias -- Immunosuppression in the ERA of Biological Agents / Josep M. Grinyó, Josep M. Cruzado, Oriol Bestard, J. R. Vidal Castiñeira and Joan Torras -- Transgenic Organs and Xenotransplants / Cristina Costa Vallés and Rafael Máñez Mendiluce -- Cell and Tissue Therapy in Regenerative Medicine / Ana Sánchez, Thomas Schimmang and Javier García-Sancho -- Section II. Adult Stem Cells -- Characteristics of Adult Stem Cells / Manuel A. Gonzalez and Antonio Bernad -- Bone Marrow Transplantation Extends Its Scope / Fermín M. Sánchez-Guijo, Alberto Orfao and María Consuelo del Cañizo -- Biology of Stem Cells: The Role of Microenvironments / Agustín G. Zapata, David Alfaro and Javier García-Ceca -- Mobilization and Homing of Hematopoietic Stem Cells / Beatriz Suárez-Álvarez, Antonio López-Vázquez and Carlos López-Larrea -- Great Promise of Tissue-Resident Adult Stem/Progenitor Cells in Transplantation and Cancer Therapies / Murielle Mimeault and Surinder K. Batra -- Multipotent Mesenchymal Stromal Cells: Clinical Applications and Cancer Modeling / René Rodríguez, Javier García-Castro, Cesar Trigueros, Mariano García Arranz and Pablo Menéndez -- Section III. Embryonic Stem Cells -- Neural Stem Cells and Transplantation Studies in Parkinson's Disease / Ricardo Pardal and José López-Barneo -- Biological Impact of Human Embryonic Stem Cells / Miguel Martín and Pablo Menéndez -- Epigenetics of Embryonic Stem Cells / Vincenzo Calvanese and Mario F. Fraga -- New Tools in Regenerative Medicine: Gene Therapy / Miguel Muñoz Ruiz and José R. Regueiro -- Therapeutic Cloning and Cellular Reprogramming / Ramon M. Rodriguez, Pablo J. Ross and Jose B. Cibelli -- Section IV. Stem Cell Regenerative Medicine -- Advances in Stem Cell Therapy / Silvia Pérez López and Jesús Otero Hernández -- Tissue Bioengineering and Artificial Organs / Sara Llames, Eva García, Jesús Otero Hernández and Álvaro Meana.
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    Clinical potentials of stem cells: hype or hope? -- Alteration of hematopoietic stem cell fates by chromatin-modifying agents -- Increasing impact of micro RNAs in stem cell biology and medicine -- Novel strategies for the mobilization of hematopoietic stem cell -- Pluripotent stem cells from umbilical cord blood -- Good manufacturing practices: clinical-scale production of mesenchymal stem cells -- The clonal activity of marked hematopoietic stem cell -- A large animal non-injury model for study of human stem cell plasticity -- Developmental potential of somatic stem cells following injection into murine blastocysts -- Testing the limits: the potential of MAPC in animal models -- Mesenchymal stem cells as vehicles for genetic targeting of tumors -- Endothelial progenitor cells for cardiac regeneration -- Stem cells and bypass grafting for myocardial and vascular regeneration -- Adoptive immunotherapy: guidelines and clinical practice -- Immune escape and suppression by human mesenchymal stem cells -- Stem cell transplantation: the basis for successful cellular immunotherapy.
  • Chapter 1. Promises and Limitations in the Application of Cell Therapy for Tissue Regeneration / Raphael Gorodetsky -- Chapter 2. Adult Non-hematopoietic Stem Cells and Progenitor Cells (aNHSCs) / R. Schäfer and L. Dahéron -- Chapter 3. Screening Approaches for Stem Cells / David G. Buschke, Derek J. Hei, Kevin W. Eliceiri and Brenda M. Ogle -- Chapter 4. Hematopoietic Stem Cells and their Role in Regenerative Medicine / Eitan Fibach -- Chapter 5. Cord and Cord Blood: Valuable Resources with Potential for Liver Therapy / Saba Habibollah, Marcin Jurga, Nico Forraz and Colin McGuckin -- Chapter 6. Induced Pluripotent Stem Cells: Their Role in Modeling Disease and Regenerative Medicine / Yonatan Stelzer and Marjorie Pick -- Chapter 7. Mesenchymal Stromal/Stem Cells from Tissue Repair to Destruction of Tumor Cells / Rita Bussolari, Giulia Grisendi, Luigi Cafarelli, Pietro Loschi, Laura Scarabelli, Antonio Frassoldati, Michela Maur, Giorgio De Santis, Paolo Paolucci, Pierfranco Conte and Massimo Dominici -- Chapter 8. Fibrin-based Matrices to Support Stem Cell-Based Tissue Regeneration / Raphael Gorodetsky, Iris Mironi-Harpaz and Dror Seliktar -- Chapter 9. Culturing Non-hematopoietic Mesenchymal Stromal Cells and Requirements of GMP in Stem Cell-based Therapies / Karen Bieback, Marianna Karagianni, Gerlinde Schmidtke-Schrezenmeier, Natalie Fekete and Hubert Schrezenmeier -- Chapter 10. (Stem) Cell Based Therapy for Neurological Disorders / O. Einstein and T. Ben-Hur -- Chapter 11. Mesenchymal Osteogenic Precursors for Bone Repair and Regeneration / Nicola Baldini, Dante Dallari and Francesca Perut -- Chapter 12. Stem Cells and Cartilage Repair / Bernd Rolauffs, Andreas Badke, Kuno Weise, Alan J. Grodzinsky and Wilhelm K. Aicher -- Chapter 13. Stem Cell-based Replacement Tissue for Heart Repair / Ayelet Lesman and Shulamit Levenberg -- Chapter 14. Regeneration of the Vascular System / M. Schleicher, A. J. Huber, H. P. Wendel and U. A. Stock -- Chapter 15. Regenerative Strategies for the Endocrine Pancreas: From Islets to Stem Cells and Tissue Reprogramming / Juan Domínguez-Bendala and Camillo Ricordi -- Chapter 16. Regeneration of the Lower Urinary Tract: Clinical Applications and Future Outlook / Markus Renninger, Bastian Amend, Jörg Seibold, Gerhard Feil, Arnulf Stenzl and Karl-Dietrich Sievert -- Chapter 17. Effective Tissue Repair and Immunomodulation by Mesenchymal Stem Cells within a Milieu of Cytokines / Philip Lim, Shyam A. Patel and Pranela Rameshwar -- Chapter 18. Homing of Mesenchymal Stromal Cells / Reinhard Henschler, Erika Deak and Richard Schäfer.
  • Stem cells 2006
  • pt. 1. Stem cell biology -- pt. 2. Epigenetic and microRNA regulation in stem cells -- pt. 3. Stem cells for therapeutic applications -- pt. 4. Nuclear reprogramming and induced pluripotent stem cells -- pt. 5. Tissue engineering -- pt. 6. Regenerative medicine.
  • Use of Human Embryonic Stem Cells in Therapy -- Human Neural Stem Cell-based Cell- and Gene-therapy for Neurological Diseases -- Vascular Stem Cell Therapy -- Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications -- Blood Cell Bioprocessing: The Haematopoietic System and Current Status of In-vitro Production of Red Blood Cells -- Bioprocessing Challenges Associated with the Purification of Cellular Therapies -- Separation Technologies for Stem Cell Bioprocessing.
  • The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.
  • The challenge for stem cell therapy: overview of the problem: heart attack and heart failure -- Hematopoietic stem cells for myocardial regeneration -- Mesenchymal stem cells for cardiac therapy -- Multipotent adult progenitor cells -- Mesenchymal progenitor cells for vascular formation and cardiac muscle regeneration -- Umbilical cord blood stem cells for myocardial regeneration and angiogenesis -- Endogenous cardiac stem cells -- Embryonic stem cells for myocardial repair -- Chemokin and homing factor expression in acute myocardial infarction and chronic heart failure -- Stem cell differentiation toward a cardiac myocyte phenotype -- Electrical coupling and/or ventricular tachycardia risk of cell therapy -- Cell therapy for myocardial damage: arrhythmia risk and mechanisms -- Aspects of percutaneous cellular cardiomyoplasty -- Stem cells and myocardial regeneration: open-chest/minimally invasive surgical techniques -- Measures of effective cell based therapies -- Whole bone marrow transplantation -- Clinical angioblast therapy -- Use of skeletal myoblasts for the treatment of chronic heart failure -- Bone marrow and angioblast transplantation -- Strategies for cytokine modification and stem cell mobilization for acute myocardial infarction -- 21 summary and future challenges.
  • pt. 1. Defining, isolating, and characterizing various stem and progenitor cell populations for neovascularization -- pt. 2. In vitro studies for angiogenesis, vasculogenesis, and arteriogenesis -- pt. 3. Stem cell mobilization strategies -- pt. 4. Stem cell transplantation strategies.
  • Stem cells for myocardial repair and regeneration : where are we today? / Randall J. Lee -- Bone marrow-derived endothelial progenitor cells : isolation and characterization for myocardial repair / Masaaki Ii -- Umbilical cells stem cells for myocardial repair and regeneration / Nicholas Greco and Mary J. Laughlin -- Isolation of resident cardiac progenitor cells by Hoechst 33342 staining / Otmar Pfister ... [et al.] -- Mesenchymal stem cell therapy for cardiac repair / Andrew J. Boyle, Ian K. McNiece, and Joshua M. Hare -- Methods for human embryonic stem cells derived cardiomyocytes cultivation, genetic manipulation, and transplantation / Gil Arbel ... [et al.] -- Experimental cell transplantation therapy in rat myocardial infarction model including nude rat preparation / Wangde Dai and Robert A. Kloner -- Large animal model of heart failure for assessment of stem cells / Sharad Rastogi -- Histopathologic assessment of myocardial regeneration / Naima Carter-Monroe ... [et al.] -- Assessment of myocardial angiogenesis and vascularity in small animal models / Matthew L. Springer -- Superparamagnetic iron oxide labeling of stem cells for MRi tracking and delivery in cardiovascular disease / Dorota A. Kedziorek and Dara L. Kraitchman -- Embryonic stem cell biology : insights from molecular imaging / Karim Sallam and Joseph C. Wu -- Genetic fate-mapping for studying adult cardiomyocyte replenishment after myocardial injury / Sunny S.-K. Chan ... [et al.] -- In vitro electrophysiological mapping of stem cells / Seth Weinberg, Elizabeth A. Lipke, and Leslie Tung -- Assessment of cardiac conduction : basic principles of optical mapping / Chunhua Ding and Thomas H. Everett IV -- Surface patterning for generating defined nanoscale matrices / Karen L. Christman and Heather D. Maynard.
  • Stem Cells Handbook, second edition, emphasizesthe advances in understanding and working with embryonic and fetal stem cells as well as induced pluripotent stem cells that show the most promise for clinical use. This new edition has been completely rewritten and updated to reflect the significant advances made in this field since publication of the first edition in 2004. The thirty-six chapters in this book all written by recognized experts in Stem Cell research reflect the tremendous progress in the understanding of stem cell biology and the appreciation of the potential for using stem cells for therapy of cancer, aging, injury and congenital diseases. Arguably the biggest advances have been made in obtaining different populations of stem cells, inducing mature cells to act like stem cells, and the ever-critical issue of how to get these stem cells to expand and differentiate into the tissue precursor cells that then can be used to replace lost of damaged tissues. No less exciting are the recent advances in understanding how stem cells function to maintain tissue integrity and how to use this knowledge to prevent developmental abnormalities. Other key topics discussed include: properties of tissue stem cells, transplantation of stem cells, the stem cell as a target for cancer treatment and prevention.
  • Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed, and the wide range of aesthetic procedures involving stem cell fat transfer are then described in detail. These procedures relate to the face, breast, buttocks, legs, hands, penis, and Poland syndrome. In addition, potential risks and complications are identified. Stem Cells in Aesthetic Procedures: Art, Science, and Clinical Techniques is completely up to date and has been written by leading experts in the field. It will be an invaluable source of information for students, beginners, and experienced surgeons in the fields of plastic surgery, general surgery, cosmetic surgery, facial plastic surgery, otolaryngology, ophthalmology, and oral maxillofacial surgery.
  • Generation of islet-like structures from ES cells / Nadya Lumelsky -- The therapeutic potential of liver repopulation for metabolic or endocrine disorders / Sanjeev Gupta -- The manipulation of mesenchymal stem cells for bone repair / Shelley R. Winn -- Spermatogenesis from transplanted spermatogenic stem cells / Michael D. Griswold and Derek McLean -- Hematopoietic stem cell transplant in the treatment of autoimmune endocrine disease / Jody Schumacher and Ewa Carrier -- Preclinical trials for stem cell therapy / Linda B. Lester, K.Y. Francis Pau, and Don P. Wolf. Pt. I. Basic stem cell biology. Embryonic stem cells: derivation, properties, and therapeutic implications / Victor L. Browning and Jon S. Odorico -- Germ line stem cells / Makoto C. Nagano -- Umbilical cord stem cells / Kathy E. Mitchell -- Differentiation potential of adult stem cells / Henry E. Young and Asa C. Black, Jr. -- Growth conditions for primate vs murine embryonic stem cells / Gillian M. Beattie ... [et al.] -- Pt. II. Translational research. Islet precursor cells in adult pancreatic islets / Gladys Teitelman and Irem Nasir -- Transcription factor-directed differentiation of stem cells along an endocrine lineage / William L. Lowe, Jr. --
  • Derivation and manipulation of murine embryonic stem cells / Alexander Meissner, Sarah Eminli, and Rudolf Jaenisch -- Patterning mouse and human embryonic stem cells using micro-contact printing / Raheem Peerani ... [et al.] -- Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi / Asmin Tulpule and George Q. Daley -- Measurement of cell-penetrating peptide-mediated transduction of adult hematopoietic stem cells / Aziza P. Manceur and Julie Audet -- Stem cell sources for regenerative medicine / Ali M. Riazi, Sarah Y. Kwon, and William L. Stanford -- Investigating the interactions between haemopoietic stem cells and their niche : methods for the analysis of stem cell homing and distribution within the marrow following transplantation / Brenda Williams and Susan K. Nilsson -- Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells / Valérie Cortin, Nicolas Pineault, and Alain Garnier -- Ex vivo generation of human red blood cells : a new advance in stem cell engineering / Luc Douay and Marie-Catherine Giarratana -- Isolation and manipulation of mammalian neural stem cells in vitro / Claudio Giachino, Onur Basak, and Verdon Taylor -- Isolation, expansion, and differentiation of mouse skin-derived precursors / Karl J.L. Fernandes and Freda D. Miller -- Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord / Hynek Wichterle, Mirza Peljto, and Stephane Nedelec -- Transplantation of neural stem/progenitor cells into developing and adult CNS / Tong Zheng ... [et al.] -- Transplantation of embrynic stem cell-derived dopaminergic neurons in MPTP-treated monkeys / Jun Takahashi, Yasushi Takagi, and Hidemoto Saiki -- Isolation and culture of epithelial stem cells / Jonathan A. Nowak and Elaine Fuchs -- Regeneration of skin and cornea by tissue engineering / Danielle Larouche ... [et al.] -- Prospective isolation of mesenchymal stem cells from mouse compact bone / Brenton J. Short, Nathalie Brouard, and Paul J. Simmons -- Isolation, propagation, and characterization of human umbilical cord perivascular cells (HUCPVCs) / Rahul Sarugaser ... [et al.] -- Bone marrow-derived mesenchymal stem cells : isolation, expansion, characterization, viral transduction, and production of conditioned medium / Massimilano Gnecchi and Luis G. Melo -- Template DNA-strand co-segregation and asymmetric cell division in skeletal muscle stem cells / Vasily Shinin, Barbara Gayraud-Morel, and Shahragim Tajbakhsh -- Isolation and grafting of single muscle fibres / Charlotte A. Collins and Peter S. Zammit -- Differentiation and dynamic analysis of primitive vessels from embryonic stem cells / Gefei Zeng and Victoria L. Bautch -- Derivation of contractile smooth muscle cells from embryonic stem cells / Sanjay Sinha, Mark H. Hoofnagle, and Gary K. Owens -- Islet-derived progenitors as a source of in vitro islet regeneration / Stephen Hanley and Lawrence Rosenberg -- Isolation and characterization of hepatic stem cells, or "oval cells," from rat livers / Thomas D. Shupe ... [et al.] -- Reprogramming of liver to pancreas / Shifaan Thowfeequ ... [et al.]
  • "In this state-of-the-art exploration of a hugely dynamic and fast-evolving field of research, leading researchers share their collective wisdom on the role that stem cells could play in the context of physiological stress and lung injury. The text focuses on reviewing the most relevant -- and recent -- ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages. Our entire blood supply passes through the lung's alveolar units during oxygenation. This interaction with the outside world, along with the intricacies of its structure, makes the lung a highly susceptible organ that is vulnerable to numerous types of injury and infection. This means that the mechanisms of lung repair are in themselves correspondingly complex. Because of their multipotentiality, as well as the fact of the lung's relatively rapid cell turnover, stem cells are thought to be an important alternative cell-base therapy in lung injury. Despite the controversial nature of stem cell research, there has been growing interest in both local and endogenous stem cells in the lung. This highly topical book with chapters on everything from using mesenchymal stem cells in lung repair to the effect of physical activity on the mobilization of stem and progenitor cells, represents an exciting body of work by outstanding investigators and will be required reading for those with an interest in the subject."--Publisher's website.
  • Biology of the cell -- Embryonic development -- What are stem cells? -- Of mice and men: the history of the stem cell -- Origins and types of stem cells -- Cloning -- Regenerative medicine: clinical applications of stem cells -- Cardiomyocytes from stem cells: what can we do with them? -- Stem cell tourism --Stem cells in cancer and cancer stem cells -- Stem cells for discovery of effective and safe new drugs -- Legal and intellectual property issues associated with stem cells -- Stem cell perspectives: a vision of the future.
  • Myogenic potential of stem cells: in vivo assessment / Maximilien Bencze [and five others] -- Urine-derived stem cells: biological characterization and potential clinical applications / Guihua Liu, Chunhua Deng and Yuanyuan Zhang -- Immunoregulatory properties of mesenchymal stem cells: in vitro and in vivo / Pinar Çetinalp Demircan [and three others] -- Current research on stem cells in Parkinson's Disease: progress and challenges / Ria Thomas and Jan Pruszak -- Stem cell applications in retinal diseases / Güngör Sobacı -- Potential use of dental stem cells for craniofacial tissue regeneration / Mustafa Ramazanoglu [and three others] -- Pediatric diseases and stem cells: recent advances and challenges / Duygu Uçkan -- Stem cell therapy: from the heart to the periphery / Bernd Stratmann and Diethelm Tschoepe -- Stem cells in wound healing / Dilek Telci, Ayca Zeynep Ilter and Merve Erdem -- Cancer stem cells: the gist of the matter / Torben Redmer [and five others] -- Filling the gap in the relationship between cancer and stem cells / Erdal Karaoz [and two others] -- Neural stem cells as therapeutic delivery vehicles for malignant brain tumors / Tugba Bagci-Onder -- Therapy resistance in prostate cancer: a stem cell perspective / Sandra Klein [and three others] -- Mechanisms of somatic cell reprogramming / Tamer T. Onder -- Disease modeling and drug discovery using human pluripotent stem cells / Christian Honoré and Mattias Hansson -- Stem cell research: ethical considerations / Berna Arda [and two others].
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  • 2005 books24x7, SUNet ID login required.
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    Basic concepts -- The nervous system -- The cardiovascular system -- The respiratory system -- The gastrointestinal system -- The renal system -- The endocrine system -- The reproductive system -- The musculoskeletal system -- The hematopoietic and lymphoreticular system.
  • . Case for Evidence-Based Stepped Care as Part of a Reformed Delivery System / Crissa Draper -- 2. Depression and a Stepped Care Model / Scott T. Gaynor -- 3. Anxiety / Holly Hazlett-Stevens -- 4. Panic Disorder / Per Carlbring -- 5. Post-traumatic Stress Disorder / Matthew Ghiglieri -- 6. Social Phobia (Social Anxiety Disorder) / Per Carlbring -- 7. Substance Abuse / Jason Lillis -- 8. Evaluating a Web-Based Cognitive Behavioral Intervention for the Prevention and Treatment of Pediatric Obesity / William T. O'Donohue -- 9. Chronic Disease Management / Victoria Mercer -- 10. Oppositional Defiant Disorder / Bruce M. Gale -- 11. Autism / Michele P. Steever -- 12. Grief / Brett Litz -- 13. Sexual Disorders / M. Todd Sewell -- 14. Stepped Care and E-Health in Behavioral Managed Care / Ronald R. O'Donnell -- 15. Cultural Considerations in Stepped-Care and E-Health Interventions / Chelsea Klinkebiel.
  • Definition, prevalence, and burden of oropharyngeal dysphagia : a serious problem among older adults worldwide and the impact on prognosis and hospital resources / Cichero, J.A.Y. ; Altman, K.W. -- The physiology of deglutition and the pathophysiology and complications of oropharyngeal dysphagia / Steele, C.M. -- Identifying vulnerable patients : role of the EAT-10 and the multidisciplinary team for early intervention and comprehensive dysphagia care / Kaspar, K. ; Ekberg, O. -- The volume-viscosity swallow test for clinical screening of dysphagia and aspiration / Rofes, L.; Arreola, V.; Clavé, P. -- Videofluoroscopic swallow study : techniques, signs, and reports / Bülow, M. -- Screening and clinical assessment of oropharyngeal dysphagia / Martino, R -- Pathophysiology, relevance, and natural history of oropharyngeal dysphagia among older people / Clavé, P. ... [et al.] -- Complications of oropharyngeal dysphagia : aspiration pneumonia / Almirall, J.; Cabré, M.; Clavé, P. -- Nutrition assessment and intervention in the patient with dysphagia : challenges for quality improvement / Ochoa, J.B. -- Therapeutic approach to malnutrition and sarcopenia / Burgos Peláez, R. -- Importance of nutritional support in older people / Sánchez-García, E. ... [et al.] -- Exercise-based approaches to dysphagia rehabilitation / Steele, C.M. -- Oropharyngeal dysphagia pathophysiology, complications, and science-based interventions / Altman, K.W. -- Concluding remarks.
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    Normal anatomy -- Congenital malformations -- Degenerative lesions --Inflammatory lesions -- Tumors -- Traumatic lesions -- Surgery-related lesions.
  • Since its introduction about sixty years ago, stereotactic and functional neurosurgery has evolved into a fascinating and interdisciplinary endeavor that combines modern neurosurgery, neurobiology, and neuroimaging with innovative diagnostic and treatment strategies. In this collection, acknowledged experts from Europe and North and South America present their scientific and clinical experience in stereotactic and functional neurosurgery for movement disorders and brain tumors. The contributions present a wide range from the beginnings of human stereotactic neurosurgery to the most modern molecular and restorative strategies to treat diseases of the human nervous system. They clearly demonstrate that the discipline is still young and dynamic with alternative and sometimes competing strategies whose evaluation is underway. They also document that operative lesioning techniques such as thalamotomies, though still chosen under certain circumstances, have been succeeded by novel neuromodulation techniques such as deep brain stimulation in the great majority of clinical cases.
  • Introduction / Simon S. Lo, Bin S. Teh, Jiade J. Lu and Tracey E. Schefter -- Historical Development of Stereotactic Ablative Radiotherapy / Timothy D. Solberg, Robert L. Siddon and Brian Kavanagh -- CyberKnife System / Jun Yang, John P. Lamond, Jing Feng, Xiaodong Wu and Rachelle Lanciano, et al. -- Novalis and Varian Systems / Isaac I. Rosen and Ramiro Pino -- Helical TomoTherapy System / Whitney Warren, Walter H. Grant III and Bin S. Teh -- Elekta System / Julian R. Perks, Megan E. Daly, David Schlesinger and Stanley H. Benedict -- Treatment Planning for Stereotactic Body Radiation Therapy / Moyed Miften, Shiva K. Das, Indrin J. Chetty and David Westerly -- Launching a Stereotactic Body Radiation Therapy Program / Michael Lamba -- Radiobiology of Stereotactic Body Radiation Therapy/Stereotactic Ablative Radiotherapy / Michael D. Story, Chaitanya Nirodi and Clinton Park -- Primary Lung Cancer / Joe Y. Chang, Shervin M. Shirvani, Billy W. Loo Jr., John P. Lamond and Ben J. Slotman, et al. -- Primary Liver Cancer / Higinia R. Cárdenes and Foster Lasley -- Prostate Cancer / Hiromichi Ishiyama, Alan Katz, Angel I. Blanco, Jose Hinojosa and Simon S. Lo, et al. -- Renal Cell Carcinoma / Bin S. Teh, Hiromichi Ishiyama, Angel I. Blanco, Lee E. Ponsky and Simon S. Lo, et al. -- Gynecologic Cancer / Charles A. Kunos, Jeffrey Fabien, Yuxia Zhang, James Brindle and Nina A. Mayr -- Pancreatic Cancer / A. Yuriko Minn, Daniel T. Chang and Albert C. Koong -- Benign and Malignant Primary Spinal Tumors / Brett Cox, Iris C. Gibbs and Yoshiya Yamada -- Non-Skull Base Head and Neck Cancer / Farzan Siddiqui, David Raben, Sue S. Yom, Jiade J. Lu and Min Yao -- Skull Base Head and Neck Cancer / Sue S. Yom, David Raben, Farzan Siddiqui, Jiade J. Lu and Min Yao -- Lung Metastasis / Neha Amin, Tracey E. Schefter, Paul Okunieff, Brian Kavanagh and Michael T. Milano -- Liver Metastasis / Michelle Stinauer, Rachelle Lanciano, Tracey E. Schefter, Brian Kavanagh and Julie A. Carlson, et al. -- Adrenal Metastasis / Mirna Abboud, Simon S. Lo, Arnold C. Paulino, Daniel E. Lehane and Bin S. Teh -- Histology-Specific Metastasis / Michael T. Milano and Joseph K. Salama -- Bone Metastasis / Mirna Abboud, Arnold C. Paulino, B. S. Teh, Simon S. Lo and Rex Marco -- Spinal Metastasis / Simon S. Lo, Andrew E. Sloan, Mitchell Machtay, Bin S. Teh and Arjun Sahgal, et al. -- Reported Toxicities Associated with Stereotactic Body Radiation Therapy / Simon S. Lo, Arjun Sahgal, Charles A. Kunos, Bin S. Teh and Min Yao, et al. -- Normal Tissue Constraints / Simon S. Lo, Arjun Sahgal, Lijun Ma, Ben J. Slotman and Zhibin Huang, et al. -- Erratum: Primary Liver Cancer / Higinia R. Cárdenes and Foster Lasley -- Erratum: Bone Metastasis / Mirna Abboud, Arnold C. Paulino, B. S. Teh, Simon S. Lo and Rex Marco.
  • Stereotactic body radiation therapy : lung cancer / Simon S. Lo, Bin S. Teh, Nina A. Mayr & Mitchell Machtay -- Stereotactic body radiation therapy and lung cancer / Gregory M.M. Videtic -- Radiobiology of stereotactic body radiation therapy / Zhibin Huang, Nina A. Mayr, Simon S. Lo & William Yuh -- SBRT : frame-based and image-guided strategies / Meredith Elana Giuliani & Andrea Bezjak -- CyberKnife®-based SBRT for lung cancer / Martina Descovich, Danita Kannarunimit & Sue S. Yom -- SBRT : evolving standards in tumor response evaluation / W. Alexander Wilson & Ronald C. McGarry -- Radiation pneumonitis prediction and management / Robert Bryan Barriger -- Chest wall toxicities : prediction and management / Robert Bryan Barriger -- Surgery versus SBRT for early-stage lung cancer : a new treatment option? / W. Alexander Wilson & Ronald C. McGarry -- Target contouring & treatment planning in lung SBRT / Meredith Elana Giuliani & Jean-Pierre Bissonnette -- Ask the experts : strategies to minimize complications from SBRT for lung cancer / Simon S. Lo, Bin S. Teh, Nina A. Mayr & Mitchell Machtay -- Multiple choice questions : answers.
  • This practical guide covers the basic aspects of stereotactic radiotherapy systems and treatment. As an emerging field, stereotactic body radiotherapy (SBRT) offers image-guided radiation that is directed at extremely well-defined tumor targets within the body, delivering very high doses of radiation. Indications for SBRT have expanded extensively in recent years from intracranial treatment to extracranial, leading to the development of a thriving subspecialty within radiation oncology. The expertise on these methods is concentrated across a few centres, mainly in the USA. However, as the technique is increasingly being adopted worldwide, specialists require further training in using it. Stereotactic Body Radiotherapy ? A Practical Guide provides a valuable aid for this purpose and is of particular interest to clinical oncologists and their trainees.
  • This comprehensive book encompasses various facets of sterile product development. Key concepts relevant to the successful development of sterile products are illustrated through case studies and are covered under three sections in this book: Formulation approaches that discuss a variety of dosage forms including protein therapeutics, lipid-based controlled delivery systems, PEGylated biotherapeutics, nasal dosage form, and vaccines, Process, container closure and delivery considerations including freeze-thaw process challenges, best practices for technology transfer to enable commercial product development, innovations and advancement in aseptic fill-finish operations, approaches to manufacturing lyophilized parenteral products, pen / auto-injector delivery devices, and associated container closure integrity testing hurdles for sterile product closures, Regulatory and quality aspects in the areas of particulate matter and appearance evaluation, sterile filtration, admixture compatibility considerations, sterilization process considerations, microbial contamination investigations and validation of rapid microbiological methods, and dry and moist heat sterilizers This book is a useful resource to scientists and researchers in both industry and academia, and it gives process and product development engineers insight into current industry practices and evolving regulatory expectations for sterile product development.
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    This book is the first comprehensive analysis of eugenics in North America focused on the second half of the twentieth century. Based on new research the authors show why eugenic sterilization policies persisted after the 1940s in the United States and Canada. Through extensive archival research,they show how both superintendents at homes for the 'feebleminded' and pro-sterilization advocates repositioned themselves after 1945 to avoid the taint of Nazi eugenics. Drawing on interviews with victims of sterilization and primary documents, this book traces the post-1940s development of eugenic policy and shows that both eugenic arguments and committed eugenicists informed population, welfare, and birth control policy in postwar America. In providing revisionist histories of the choice movement, the anti-population growth movement, and the Great Society programs, this book contributes to public policy and political and intellectual history.
  • "Sternberg's Diagnostic Surgical Pathology is the flagship book on LWW's pathology list. This classic 2-volume reference presents advanced diagnostic techniques and the latest information on all currently known diseases. The book emphasizes the practical differential diagnosis of the surgical specimen while keeping to a minimum discussion of the natural history of the disease, treatment and autopsy findings. Contributors are asked to provide their expert advice on the diagnostic evaluation of every type of specimen from every anatomic site. This approach distinguishes it from its key competition and provides a style of a personal consultation"-- Provided by publisher.
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  • Histology -- The cell -- Epithelial cells -- Support cells and the extracellular matrix -- Contractile cells -- Nervous tissue -- Blood cells -- Immune system -- Blood and lymphatic circulatory systems and heart -- Respiratory system -- Alimentary tract -- Liver -- Musculoskeletal system -- Endocrine system -- Urinary system -- Male reproductive system -- Female reproductive system -- Skin and breast -- Special senses.
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  • This Forum on Health and National Security, directed to addressing stigma and barriers to care, brought together a diverse group of leaders in order to expand horizons on these issues of important national need in times of war, disaster and terrorism. The individuals represented national leaders, educators, researchers and health care planners across mental health, health care systems, military and disaster care and the specific issues of stigma and barriers to care. The goal was for individuals who did not usually talk with each other or even know of each other's work, to hear new perspectives and create a new vantage point on this difficult topic.
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    Part 1. Tom the Scot -- 1. The Demographic setting; Scotland -- 2. The Scottish phase -- 3. Schooling and University Medical School -- 4. Tom the scientist clinician; how the apprentice became a pioneer of haemophilia research -- Interlude - Journey to San Francisco -- Part 2. Tom the American -- 5. California and San Francisco -- 6. American family connections -- 7. Tom the scientist clinician in America -- 8. Tom the social and political activist -- 9. Last years -- Notes and references from archived sources.
  • Technology for peripheral nerve stimulation / Parker, J.L., Cameron, T. -- Theoretical basis of vagal nerve stimulation / Attenello, F., Amar, A.P., Liu, C., Apuzzo, M.L.J. -- Vagal nerve stimulation : surgical technique and complications / Tronnier, V.M. -- Vagus nerve stimulation for epilepsy : an evidence-based approach / Cukiert, A. -- Vagus nerve stimulation for major depressive episodes / Eljamel, S. -- Phrenic nerve stimulation : technology and clinical applications / Abdunnur, S.V., Kim, D.H. -- Trigeminal ganglion stimulation / Van Buyten, J.-P. -- Carotid sinus/nerve stimulation for treatment of resistant hypertension and heart failure / Yin, D., Slavin, K.V. -- Hypoglossal nerve stimulation for obstructive sleep apnea / Mwenge, G.B., Rombaux, P., Lengele, B., Rodenstein, D. -- Sphenopalatine ganglion stimulation in neurovascular headaches / Schoenen, J. -- Occipital stimulation for migraine : update from recent multicenter trials -- Schwedt, T.J., Green, A.L., Dodick, D.W. -- Peripheral nerve stimulation for back pain / Verrills, P., Russo, M. -- Peripheral nerve stimulation for pain in extremities : an update / Pope, J.E., Carlson, J.D., Rosenberg, W.S., Slavin, K.V., Deer, T.R. -- Peripheral neuromodulation to treat postamputation pain / Soin, A., Fang, Z.-P., Velasco, J. -- Peripheral neurostimulation with a microsize wireless stimulator / Yearwood, T.L., Perryman, L.T. -- Sacral neuromodulation for genitourinary problems / Banakhar, M., Hassouna, M. -- Sacral nerve stimulation in the treatment of bowel disorders / Nordenstam, J., Boller, A.-M., Mellgren, A. -- Stimulation of the dorsal root / Ganglion Liem, L. -- Regulation of peripheral nerve stimulation technology / Birk, D.M., Yin, D., Slavin, K.V.
  • Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authors concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation.
  • "Revised and updated for its Third Edition, Stocker and Dehner's Pediatric Pathology provides encyclopedic coverage of the diagnosis of pediatric disorders from the neonatal period through adolescence. It covers all major aspects of the pathologic anatomy of childhood disorders ranging from chromosomal syndromes and neoplasms to forensic pathology. Sections are organized by disease classification and by organ system. The book contains more than 1,300 gross and microscopic images, including 1,200 in full color. This edition includes a new chapter on transplantation pathology. Other highlights include significant updates in the areas of pediatric autopsy, imaging techniques, molecular techniques, embryonic and fetal wastage, congenital abnormalities, metabolic disorders, SIDS and forensic pathology, the placenta, and the nervous system"--Provided by publisher.
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    1 General considerations and an outline survey of some basic interaction mechanisms -- 2 ACE inhibitors and angiotensin II receptor antagonists -- 3 Alcohol -- 4 Alpha blockers -- 5 Anaesthetics and neuromuscular blockers -- 6 Analgesics and NSAIDs -- 7 Anorectics and stimulants -- 8 Anthelmintics, antifungals and antiprotozoals -- 9 Antiarrythmics -- 10 Antibacterials -- 11 Anticholinesterases -- 12 Anticoagulants -- 13 Antidiabetics -- 14 Antiepileptics -- 15 Antihistamines -- 16 Antimigraine drugs -- 17 Antineoplastics -- 18 Antiparkinsonian and related drugs -- 19 Antiplatelet drugs and thrombolytics -- 20 Antipsychotics, anxiolytics and hypnotics -- 21 Antivirals -- 22 Beta blockers -- 23 Calcium-channel blockers -- 24 Cardiovascular drugs, miscellaneous -- 25 Digitalis glycosides -- 26 Diuretics -- 27 Gastrointestinal drugs -- 28 Hormonal contraceptives and sex hormones -- 29 Immunosuppressants -- 30 Lipid regulating drugs -- 31 Lithium -- 32 MAOIs -- 33 Respiratory drugs -- 34 -- SSRIs, tricyclics and related antidepressants -- 35 Miscellaneous drugs.
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    Ischemic heart disease / Shamsuddin Akhtar -- Valvular heart disease / Adriana Herrera -- Congenital heart disease / Inna Maranets and Roberta L. Hines -- Abnormalities of cardiac conduction and cardiac rhythm / Kelly Teed Watson -- Systemic and pulmonary arterial hypertension / Matthew C. Wallace and Ala Sami Haddadin -- Heart failure and cardiomyopathies / Wanda M. Popescu -- Pericardial diseases and cardiac trauma / Raj K. Modak -- Vascular disease / Marbelia Gonzalez -- Respiratory diseases / Viji Kurup -- Diseases affecting the brain / Jeffrey J. Pasternak and William L. Lanier, Jr. -- Spinal cord disorder / Jeffrey J. Pasternak and William L. Lanier, Jr. -- Diseases of the autonomic and peripheral nervous systems / Jeffrey J. Pasternak and William L. Lanier, Jr. -- Diseases of the liver and biliary tract / Katherine E. Marschall -- Diseases of the gastrointestinal system/ Hossan Tantawy -- Nutritional diseases and inborn errors of metabolism / Hossan Tantawy -- Renal diseases / Susan Garwood -- Fluid, electrolytes, and acid-base disorders / Susan Garwood -- Endocrine disease / Russell T. Wall III -- Hematologic disorders / Christine S. Rinder -- Skin and musculoskeletal diseases / Jeffrey J. Schwartz -- Infectious diseases / Michael S. Avidan -- Cancer / Nalini Vadivelu -- Diseases related to immune system dysfunction / Christine S. Rinder -- Psychiatric disease/substance abuse/drug overdose / Roberta L. Hines, Katherine E. Marschall -- Pregnancy-associated diseases / Ferne R. Braveman -- Pediatric diseases / Charles Lee ... [et al.] -- Geriatric disorders / Zoltan G. Hevesi.
  • With this book you'll have the succinct, yet guidance you need to successfully avoid or manage complications stemming from pre-existing medical conditions. Advanced research from experts in the field will help you overcome the toughest challenges in practice, letting you offer your patients the best care, each and every time. Search through current and concise descriptions of pathophysiology of diseases and their impact on anesthesia! Gain expertise in understanding the impact of pathophysiology of coexisting diseases on anaesthesia!
  • Store-operated Ca2+ entry (SOCE) serves to control essential functions throughout the human body and represents a novel and attractive target for therapeutic intervention. This book provides an extensive overview of the role of SOCE pathways in Molecular Physiology and Cell Biology, as well as their clinical significance. (Patho)physiological principles and emerging therapeutic strategies are delineated in a way that is valuable both for the education of graduate students in advanced Cell Biology/Molecular Physiology and for the promotion of innovative research and developments in the clinical/therapeutic fields. A comprehensive, clear and elaborate representation of current concepts is provided, including a pathophysiological section arranged in a tissue/organ/system-oriented manner. The book is intended for basic researchers specializing in cell signaling, ion transport, or pharmacology, as well as biomedical scientists and clinicians with a focus on immunology, neurology or cardiology.
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    Foreward: The Lasting Legacy of Sidney R. Garfield, M.D. / by Jay Crosson -- Preface -- Prologue: The Desert Doctor -- 1. Out of the Immigrant Forge -- 2. The Great Depression and "Social Medicine" -- 3. Revolution in the Economics of Medicine -- 4. A Fateful House Call -- 5. The Final Dress Rehearsal -- 6. FDR to Garfield: "You're Not in the Army Now!" -- 7. Postwar Challenges: Rebuilding Against a Tide of Opposition -- 8. Attack from the Rear Guard -- 9. Prosperity in the Postwar Boom -- 10. Toward Tahoe: Crises and Crossroads -- 11. After Tahoe: Pursuing New Frontiers -- 12. The Best is Yet to Come -- Appendix 1. Remarks to the AMA on Promoting Prepaid Group Practice -- Appendix 2. A Report on Permanente's First 10 Years -- Appendix 3. From An Address to the Permanente Monterey Management Conference -- Appendix 4. From An Address to the Board of Directors of The Permanente Medical Group -- Appendix 5. The Delivery of Medical Care / by Sidney R. Garfield -- Bibliography -- Selected Works: Authored or Coauthored by Sidney R. Garfield, M.D. (p. 135-137) -- Index -- A Timeline of the Life of Sidney R. Garfield, M.D.
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    A Harvard evolutionary biologist presents an engaging discussion of how the human body has evolved over millions of years, examining how an increasing disparity between the needs of Stone Age bodies and the realities of the modern world are fueling a paradox of greater longevity and chronic disease.
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  • Technology is essential to the delivery of health care but it is still only a tool that needs to be deployed wisely to ensure beneficial outcomes at reasonable costs. Among various categories of health technology, medical equipment has the unique distinction of requiring both high initial investments and costly maintenance during its entire useful life. This characteristic does not, however, imply that medical equipment is more costly than other categories, provided that it is managed properly. The foundation of a sound technology management process is the planning and acquisition of equipment, collectively called technology incorporation. This lecture presents a rational, strategic process for technology incorporation based on experience, some successful and many unsuccessful, accumulated in industrialized and developing countries over the last three decades. The planning step is focused on establishing a Technology Incorporation Plan (TIP) using data collected from an audit of existing technology, evaluating needs, impacts, costs, and benefits, and consolidating the information collected for decision making. The acquisition step implements TIP by selecting equipment based on technical, regulatory, financial, and supplier considerations, and procuring it using one of the multiple forms of purchasing or agreements with suppliers. This incorporation process is generic enough to be used, with suitable adaptations, for a wide variety of health organizations with different sizes and acuity levels, ranging from health clinics to community hospitals to major teaching hospitals and even to entire health systems. Such a broadly applicable process is possible because it is based on a conceptual framework composed of in-depth analysis of the basic principles that govern each stage of technology lifecycle. Using this incorporation process, successful TIPs have been created and implemented, thereby contributing to the improvement of healthcare services and limiting the associated expenses.
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  • A structured strategic management approach is what's needed to tackle the revolutionary change the health care system has been experiencing. Today, health care organizations have almost universally embraced the strategic perspective first developed in the business sector and now have developed strategic management processes that are uniquely their own. Health care leaders have found that strategic thinking, planning, and managing strategic momentum are essential for coping with the dynamics of the health care industry. Strategic Management has become the single clearest manifestation of eff
  • Strategic Urban Health Communication Charles C. Okigbo, editor People are bombarded with messages continuously and sorting through them constantly. In this milieu, critical ideas about health promotion and illness prevention are forced to compete with distracting, conflicting, even contradictory information. To get vital messages through, communication must be effective, targeted, artful-in a word, strategic. Strategic Urban Health Communication provides a road map for understanding strategy, enhancing strategic planning skills, and implementing strategic communication campaigns. Deftly written chapters link the art and science of strategic planning to world health goals such as reducing health inequities and eradicating diseases. Flexibility is at the heart of these cases, which span developed and developing countries, uses of traditional and digital media, and chronic and acute health challenges. And the contributors ground their dispatches in the larger context of health promotion, giving readers useful examples of thinking globally while working locally. Included in the coverage: Urbanization, population, and health myths: addressing common misconceptions. Integrating HIV/family planning programs: opportunities for strategic communication. The role of sports in strategic health promotion in low-income areas. The Internet as a sex education tool: a case study from Thailand. Advertising and childhood obesity in China. Health communication strategies for sustainable development in a globalized world. Balancing depth of understanding of audiences and methods of reaching them, Strategic Urban Health Communication is a forward-looking resource geared toward professionals and researchers in urban health, global health, and health communication.
  • Stratified medicine : a new challenge for academia, industry, regulators and patients -- Stratified medicine : a new era in the therapeutic approach -- Challenges for academic medicine and clinicians -- Challenges for diagnostics industry -- Challenges for the pharmaceutical industry -- Separate or codevelopment of biomarker and drug : the scenarios -- Challenges for the regulatory agencies in establishing an environment favorable for stratified medicine -- Challenges for the patients facing stratified medicine & personal genomics -- Conclusions & outlook to the future health system -- Stratified medicine : a challenging social experiment.
  • "Injury accounts for a significant proportion of the world's burden of disease. Each year 5.8 million people die from injury and millions more are disabled. The response to this global health problem needs to include a range of activities, from better surveillance to more in-depth research, and primary prevention. Also needed are efforts to strengthen care of the injured. The World Health Organization (WHO) has responded to this need with a variety of actions. ... WHO collected this set of case studies, documenting success stories and lessons learned from several countries. Through this publication, WHO seeks to increase communication ... among those working in the field of trauma care in different countries worldwide."--p. iii.
  • Introduction to Cardiovascular Disease, Stress and Adaptation -- Social Stress and Cardiovascular Disease in Primates -- Cardiovascular and Autonomic Responses to Stress -- Sympathetic Neural and Adrenal Medullary Mechanisms in Depression and Panic Disorder -- Hypothalamic-Pituitary-Adrenal Axis and Cardiovascular Disease -- Haemostatic Effects of Stress -- Stress, Inflammation, and Coronary Heart Disease -- Brain Imaging of Stress and Cardiovascular Responses -- Psychological Triggers for Plaque Rupture -- Stress Cardiomyopathy -- Psychosocial Factors at Work: The Epidemiological Perspective -- Depression and Cardiovascular Disease Progression: Epidemiology, Mechanisms and Treatment -- Post-traumatic Stress Disorder: Emerging Risk Factor and Mechanisms -- Sleep, Stress, and Heart Disease -- The Causal Role of Chronic Mental Stress in the Pathogenesis of Essential Hypertension -- Metabolic Syndrome and Diabetes -- Stress Management and Behavior: From Cardiac Patient to Worksite Intervention -- Exercise to Reduce Distress and Improve Cardiac Function: Moving on and Finding the Pace -- The Psychological Treatment of Cardiac Patients -- Integrating the Management of Psychosocial and Behavior Risk Factors into Clinical Medical Practice -- Concluding Remarks.
  • Are oral disorders only an issue for dentists? The answer is no. If your patients complain of pain and/or discomfort, if some are diagnosed as suffering from migraines, fibromyalgia or chronic fatigue, and if classical therapies have remained ineffective, this book could help in your daily practice. When it comes to the complex pathology called Temporo-Mandibular Disorders (TMD) most specialists favour a multidisciplinary approach and treatment of socio-psycho-emotional factors as well as dental, lingual or postural disorders. Yet little is known - from a clinical point of view - about a tricky oral spastic habit called severe teeth clenching. In view of the lack of clinical findings from classical investigations on the subject, it could be considered as the hidden part of an oral parafunctional iceberg. Neuroscience has been able to shed some light on the multiple connections between trigeminal and non-trigeminal nervous centres, which confirms the significant involvement of the stomatognathic system and trigeminal nerves (V) in both oral as well as non-oral major functions such as eating, breathing, speaking, hearing, and standing and also confirms the extensive participation of the paired Vs in the human adaptation process. Too many physicians are still reluctant to admit the pathological responsibilities of the Vs. Therefore their role remains largely underestimated by clinicians. Stress conditions in introverted people cause a parafunctional habit (i.e. severe clenching), which in turn produces trigeminal overstimulation and nociception. Through a process of sensitization this can perturb some non-trigeminal nervous areas, such as the vestibular nuclei and cerebellum (involved in equilibrium). Would you then be willing to accept the possibility that a stressed and introverted patient who clenches hard, durably or frequently may end up suffering from dizziness? If not, this book is not for you. But if you accept the scientific data and clinical facts this book will offer a concrete therapeutic protocol: the Relaxing and Moderating Treatment (RMT), which can greatly help you to familiarize yourself with and neutralize this little known deleterious spastic oral parafunction and its many disconcerting pain-causing and dysfunctional clinical effects. Prepare to be amazed by the results, just as we were!
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    v. 1. Coping with normative transitions -- v. 2. Coping with catastrophe.
  • This book adopts an interdisciplinary approach in seeking to identify the impact of living conditions in space on the adaptation of the immune system.
  • Part I: Presentation and Diagnosis of Stress Fractures -- Pathophysiology and Epidemiology of Stress Fractures -- General Treatment Concepts for Stress Fractures -- Biomechanics and Gait Analysis for Stress Fractures -- Classification of Stress Fractures -- Imaging of Stress Fractures -- Part II: Management of Stress Fractures -- Stress Fractures of the Lumbar Spine -- Stress Fractures of the Pelvis -- Stress Fractures of the Femur -- Stress Fractures of the Patella -- Stress Fractures of the Tibia -- Stress Fractures of the Fifth Metatarsal -- Stress Fractures of the Ankle -- Stress Fractures of the Calcaneus, Sesamoids and Metatarsals -- Stress Fractures of the Ribs and Shoulder Girdle -- Upper Extremity Stress Fractures -- Insufficiency Fractures.
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    "We live in an age of stress. Constant stress significantly affects our ability to lead healthy and happy lives at work and home. We struggle with stomach pain, headaches, mood swings, fatigue, depression, high blood pressure, and even heart failure. Stress damages our physical and emotional well-being, our relationships, and our productivity. Dr. Fred Luskin and Dr. Kenneth R. Pelletier spent years at the Stanford University School of Medicine developing ten proven skills for eliminating the stress, anxiety, and pain that occur in daily life. Delivering sound advice, Stress Free for Good is easy to use and starts working immediately. This is the last stress aid you will ever need"--Book jacket.
  • Stress in America missing the health care connection. 2014
    American Psychological Association
    While the United States spends more than any other country on health care and leads the world in the quality and quantity of its health research, these trends do not add up to better health outcomes. he U.S. experiences poorer health outcomes than many other high-income countries, even while spending more money per person on health care. Compared to peers in these countries, Americans have less access to primary care, consume the most calories per person and are more likely to live in environments designed around automobiles. Research suggests that these factors contribute to the nation's poor health outcomes and survey findings show that stress influences our health behaviors, setting up teens and adults alike for potential chronic illnesses that affect quality of life and the country's health care expenditure.
  • pt. 1. Psychological challenges of heart disease -- pt. 2. Psychological interventions for cardiac patients.
  • Neurobehavioral medicine and stress-related disorders / Dirk H. Hellhammer, Juliane Hellhammer -- Neuropattern : a step towards neurobehavioral medicine / Dirk H. Hellhammer, Juliane Hellhammer -- Principles of the crosstalk between brain and body : glandotropy, ergotropy, and trophotropy / Dirk H. Hellhammer -- Hypercortisolemic disorders / Petra Pütz -- Hypocortisolemic disorders / Eva Fries -- Noradrenergic and sympathetic disorders / Pascal O. Klingmann, Dirk H. Hellhammer -- Serotonergic and parasympathetic disorders / Dirk H. Hellhammer, Pascal O. Klingmann.
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    Evaluating the role of Hans Selye in the modern history of stress / Mark Jackson -- Stress and the American vernacular : popular perceptions of disease causality / Elizabeth Siegel Watkins -- Resilience for all by the year 20? / Allan Young -- From primitive fear to civilized stress : sudden unexpected death / Otniel E. Dror -- Stress in US wartime psychiatry : World War II and the immediate aftermath / Theodore M. Brown -- The machinery and the morale : physiological and psychological approaches to military stress research in the early Cold War era / Tulley Long -- Making sense of workplace fear : the role of physicians, psychiatrists, and labor in reframing occupational strain in industrial Britain, ca. 1850-1970 / Joseph Melling -- Work, stress, and depression : the emerging psychiatric science of work in contemporary Japan / Junko Kitanaka -- The invention of the 'stressed animal' and the development of a science of animal welfare, 1947-86 / Robert G. W. Kirk -- Memorial's stress : Arthur M. Sutherland and the management of the cancer patient in the 1950s / David Cantor -- Stress in the city : mental health, urban planning, and the social sciences in the postwar United States / Edmund Ramsden -- Sadness in Camberwell : imagining stress and constructing history in postwar Britain / Rhodri Hayward.
  • 1. Stress-induced mutagenesis in bacteria / Ivan Matic -- 2. Mutagenesis associated with repair of DNA double-strand breaks under stress / Chandan Shee, P.J. Hastings, and Suman M. Rosenberg -- 3. Transcription-mediated mutagenic processes / Eduardo Robleto, Holly A. Martin, Carmen Vallin, Mario Pedraza-Reyes and Ronald Yasbin -- 4. Transposon mutagenesis in disease, drug discovery, and bacterial evolution / Zhongge Zhang, Jing Wang, Maksim A. Shlykov, and Milton H. Saier, Jr. -- 5. Hsp90 as a capacitor of both genetic and epigenetic changes in the genome during cancer progression and evolution / Xiangyi Lu, Luan Wang, Vincent E. Sollars, Mark D. Garfinkel, and Douglas M. Ruden -- 6. Inheritance of stress-induced epigenetic changes mediated by the ATF-2 family of transcription factors / Ki-Hyeon Seong, Toshio Maekawa and Shunsuke Ishii -- 7. Microsatellite repeats: canaries in the coalmine / Nimrat Chatterjee, Beatriz A. Santillan and John H. Wilson -- 8. Genetic instability induced by hypoxic stress / Susan E. Scanlon and Peter M. Glazer -- 9. Radiation-induced delayed genome instability and hypermutation in mammalian cells / Christopher P. Allen, Akira Fujimori, Ryuichi Okayasu and Jac A. Nickoloff -- 10. Radiation-induced bystander effects and stress-induced mutagenesis / Carmel Mothersill and Colin Seymour -- 11. Stress induced mutagenesis, genetic diversification, and cell survival via anastais, the reversal of late stage apoptosis / Ho Lam Tang, Ho Man Tang and Denise J. Mitchell -- 12. The transgenerational effects of parental exposure to mutagens in mammals / Yuri E. Dubrova -- 13. Revisiting mutagenesis in the age of High-throughput sequencing / Subhajyoti De and R. Matthew Ward.
  • Stroke book. 2nd ed. 2013
    Section I. Assessment of Stroke Patients -- 1. Emergency medical services (EMS): first line of defense against stroke -- 2. Initial assessment of patients with stroke-like symptoms -- 3. Clinical stroke syndromes and localization -- Section II. The Hunt for a Stroke Etiology -- 4. The Hunt for a stroke etiology: ischemic stroke -- 5. The Hunt for a stroke etiology: hemorrhagic stroke -- 6. Uncommon causes of stroke and stroke mimics -- Section III. Acute Stroke Imaging -- 7. Computed tomography in acute stroke -- 8. Magnetic resonance imaging in acute stroke -- 9. Neurosonology in acute ischemic stroke -- Section IV. Management of Stroke Patients -- 10. Ischemic stroke in the first 24 hours -- 11. Management of the acute ischemic stroke patient beyond 24 hours -- 12. Intracerebral hemorrhage -- 13. Subarachnoid hemorrhage and its medical management -- 14. Dural and cerebral venous thrombosis -- Section V. Stroke in Consultation -- 15. Perioperative stroke -- 16. Stroke on OB/Gyn wards -- 17. Stroke on pediatric wards -- Section VI. Prevention of First and Recurrent Stroke -- 18. Antithrombotic therapies -- 19. Surgical and endovascular therapies -- 20. Stroke risk factors: impact and management -- 21. Synopsis of landmark studies in ischemic stroke.
  • Chapter 1. Setting the goal for the stroke center -- chapter 2. Stroke center organization -- chapter 3. Regional stroke networks -- chapter 4. Imaging for diagnosis and selection of therapy -- chapter 5. Transient ischemic attack : TIA -- chapter 6. Acute stroke interventions -- chapter 7. Neurocritical care management of acute stroke -- chapter 8. Issues in acute management -- chapter 9. Prevention of complications -- chapter 10. Secondary prevention of stroke -- chapter 11. Stroke rehabilitation.
  • Stroke genetics 2013
    Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Â Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
  • Introduction to stroke genomics / Simon J. Read and Frank C. Barone -- Choice, methodology, and characterization of focal ischemic stroke models: the search for clinical relevance / David Virley -- Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat / Hilary V. O. Carswell ... [et al.] -- Gene therapy in neurological disease / Midori A. Yenari and Robert M. Sapolsky -- Stem cell transplantation after middle cerebral artery occlusion / Paul Stroemer and Helen Hodges -- Endogenous brain protection: models, gene expression, and mechanisms / Frank C. Barone -- Production of transgenic and mutant mouse models / Alex Harper -- 3-nitropropionic acid model of metabolic stress: assessment by magnetic resonance imaging / Toby John Roberts -- Practicalities of genetic studies in human stroke / Ahamad Hassan and Hugh S. Markus -- Evaluation of the interactions of common genetic mutations in stroke / Zoltán Szolnoki -- Technologies of disease-related gene discovery using preclinical models of stroke / Xinkang Wang -- Quantitative analysis of gene transcription in stroke models using real-time RT-PCR / David C. Harrison and Brian C. Bond -- Effective analysis of genomic data / Paul R. Nelson, Andrew B. Goulter, and Richard J. Davis -- Bioinformatic approaches to assigning protein function from novel sequence data / David Michalovich and Richard Fagan -- Pragmatic target discovery from novel gene to functionally defined drug target: the interleukin-1 story / Stuart McRae Allen.
  • Stroke in children and young adults : overview, risk factors and prognosis / Betsy B. Love, José Biller -- Applied anatomy of the brain arteries / William DeMyer -- Stroke in neonates and children : overview / Meredith R. Golomb -- Diagnostic strategies in neonates, children, and young adults with stroke / Deborah K. Sokol, Hema Patel -- Atherosclerotic cerebral infarction in young adults / José Biller, Rima M. Dafer -- Non-atherosclerotic cerebral vasculopathies / Rima M. Dafer, José Biller -- Cardiac disorders and stroke in children and young adults / José Biller, Michael J. Schneck, Betsy B. Love -- Cerebral infarction and migraine / Rima M. Dafer, José Biller. Hemostatic disorders presenting as cerebral infarction / Rima M. Dafer, José Biller -- Stroke and pregnancy / Rima M. Dafer, José Biller -- Rare genetic disorders predisposing to stroke / Betsy B. Love, James F. Meschia, José Biller -- Cerebral venous thrombosis / Rima M. Dafer, José Biller -- Neonatal intracranial hemorrhage / Eugene R. Schnitzler, Marc G. Weiss -- Spontaneous intracerebral hemorrhage / José Biller, Michael Schneck -- Subarachnoid hemorrhage in young adults / Lotfi Hacein-Bey, Thomas C. Origitano, José Biller -- Pediatric CNS vascular malformations / Thomas J. Altstadt, Mitesh V. Shah -- Vascular disorders of the spinal cord in children and young adults / Richard B. Rodgers, Michael B. Pritz.
  • Stroke management and recovery / Bruce Ovbiagele -- Stroke pathophysiology / Sarkis Morales-Vidal & José Biller -- Risk factors and primary prevention / Rita V. Krishnamurthi, Kelly M. Jones & Valery L. Feigin -- Early symptoms, signs and diagnosis of stroke / Sweta Adatia & Andrew Demchuk -- Hyperacute stroke management / Edward Jauch, Christine Holmstedt & Mark McCaslin -- In-hospital management of stroke / Michel Shamy, Karl Meisel & S. Andrew Josephson -- Medications for recurrent stroke prevention / Muhammad U. Farooq & Philip B. Gorelick -- Surgical prevention of stroke / Andrew R. Barleben, Wesley S. Moore & Thomas G. Brott -- Stroke prevention : diet and lifestyle / Jorge Pagola & Carlos A. Molina -- Multidisciplinary stroke rehabilitation and prognosis / Robert W. Teasell & Ricardo Viana -- Physical and occupational therapy / Richard D. Zorowitz -- Speech and language therapy / Marlís González-Fernández & Argye E. Hillis -- Management of postdischarge complications / Bernadette N. Borte & Enrique C. Leira -- Stroke systems of care / Alec Fraser, Charles Wolfe, Anthony Rudd & Christopher McKevitt -- Index.
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    Development of knowledge about cerebrovascular disease -- Is it a vascular event and where is the lesion? -- Which arterial territory is involved? -- What pathological type of stroke is it, cerebral ischaemeic of haemorrhage? -- What caused this transient or persisting ischaemic event? -- Unusual causes of ischaemic stroke and transient ischaemic attack -- What caused this intracerebral haemorrhage? -- What caused this subarachnoid haemorrhage? -- A practical approach to the management of stroke and transien ischaemic attack patients -- What are this person's problems? a problem-based approach to the general management of stroke -- Specific treatments for acute ischaemic stroke -- Specific treatment of intracerebral haemorrhage -- Specific treatment of aneurismal subarachonoid haemorrhage -- Specific interventions to prevent intracranial haemorrhage -- Preventing recurrent stroke and other serious vascular events -- The organization of stroke services -- Reducing the impact of stroke and improving the public health.
  • Antithrombotic management of atrial fibrillation / Ron Pisters & Harry J. Crijns -- Overview of stroke in atrial fibrillation / Hans-Christoph Diener -- Stroke risk assessment in atrial fibrillation / Stavros Apostolakis & Gregory Y.H. Lip -- Treatment recommendations and guidelines / Laurent Fauchier, Nicolas Clementy & Dominique Babuty -- Pharmacological stroke prevention: antithrombotic drugs / Christian Weimar & Ralph Weber -- Pharmacological stroke prevention : RAS inhibitors / Ole Dyg Pedersen & Christian Torp-Pedersen -- Stroke prevention : antiarrhythmic treatments / A. John Camm & Irina Savelieva -- Nonpharmacological stroke prevention strategies in atrial fibrillation patients / Alessandro Montecalvo & Ralph J. Damiano -- Antithrombotic management in the acute coronary syndrome setting / Andrea Rubboli -- Periprocedural reversal & bridging of anticoagulant treatment / Marcel Levi, Elise Eerenberg & Pieter Willem Kamphuisen -- Clinical barriers to the use of recommended stroke prevention therapy / Robby Nieuwlaat -- Novel antithrombotic agents & future directions / Renee M. Sullivan & Brian Olshansky -- Index.
  • Safety and efficacy of transplanting immortalized neural stem cells in stroke patients -- Transplantation of bone marrow stromal cells for the treatment of stroke -- Cord blood cells as a treatment for stroke -- Adipose-derived stem cells as a potential therapy for stroke -- Novel imaging modalities to monitor implanted embryonic stem cells in stroke -- Cell transplantation for intracerebral hemorrhage -- Therapeutic strategies employing endogenous neural stem cells in tissue remodeling following ischemic injury: the promise, the peril and novel future applications -- Ethics and stem cell research -- Special conditions in the design of clinical stroke trials for cell transplantation.
  • Vascular biology and athersclerosis of cerebral vessels / Sophocles Chrissobolis, Christopher G. Sobey -- Mechanisms of Thrombosis and thrombolysis / Gregory J. del Zoppo -- Cerebral blood flow and metabolism : regulation and pathophysiology in cerebrovascular disease / William J. Powers -- Histopathology of brain tissue response to stroke and injury / Roland N. Auer -- Molecular and cellular mechanisms of ischemia-induced neuronal death / Haiyue Zhang [and 6 others] -- Intracellular signaling : mediators and protective responses / John W. Thompson [and 3 others] -- The neurovascular unit and responses to ischemia / Gregory J. del Zoppo, Michael Moskowitz, Maiken Nedergaard -- Mechanisms of cerebral hemorrhage / Jaroslaw Aronowski [and 3 others] -- White matter pathophysiology / Bruce R. Ransom [and 3 others] -- Inflammation and immune response / Josef Anrather, Costantino Iadecola, John Hallenbeck -- Mechanisms of plasticity, remodeling and recovery / Zheng Gang Zhang, Michael Chopp -- Genetics and vascular biology of angiogenesis and vascular malformations / Helen Kim [and 3 others] -- Global burden of stroke / Valery L. Feigin, Rita V. Krishnamurthi -- Stroke disparities / George Howard, Virginia J. Howard -- Modifiable risk factors and determinants of stroke / Sudha Seshadri, Philip A. Wolf -- Prognosis after stroke / Tatjana Rundek, Ralph L. Sacco -- Vascular dementia and cognitive impairment / Sudha Seshadri, Alexis Economos, Clinton Wright -- Genetic basis of stroke occurrence, prevention and outcome / James F. Meschia, Daniel Woo, David Werring -- Preventing a first stroke / Larry B. Goldstein, Ralph L. Sacco -- Classification of ischemic stroke / Hakan Ay --Clinical scales to assess patients with stroke / Harold P. Adams, Jr. -- Carotid artery disease / Leo H. Bonati, Martin M. Brown -- Anterior cerebral artery disease / John C.M. Brust, Angel Chamorro -- Middle cerebral artery disease / Vijay K. Sharma, Lawrence K.S. Wong -- Posterior cerebral artery disease / Jong S. Kim -- Vertebrobasilar disease / Jong S. Kim, Louis R. Caplan -- Lcunar syndromes, lacunar infarcts, and cerebral small-vessel disease / Bo Norrving -- Intracerebral hemorrhage / Carlos S. Kase [and 3 others] -- Aneurysmal subarachnoid hemorrhage / José I. Suarez, Eric M. Bershad -- Arteriovenous malformations and other vascular anomalies / Christian Stapf -- Stroke and other vascular syndromes of the spinal cord / Joshua Z. Willey -- Cardiac diseases / David M. Greer, Shunichi Homma, Karen L. Furie -- Atherosclerotic disease of the proximal aorta / Marco R. Di Tullio, Shunichi Homma -- Stroke related to surgery and other procedures / Steven R. Messé, Michael T. Mullen -- Arterial dissections and fibromuscular dysplasia / Richard M. Zweifler, Gerald Silverboard -- Collagen vascular and infectious diseases / Jose Gutierrez, Mira Katan, Mitchell S.V. Elkind -- Reversible cerebral vasoconstriction syndromes / Aneesh B. Singhal -- Hypertensive encephalopathy / Catherine Lamy, Jean-Louis Mas -- Stroke and substance abuse / John C.M. Brust -- Moyamoya disease / Masahiro Yasaka, Takenori Yamaguchi, Jun Ogata -- CADASIL : cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy / Hugues Chabriat [and 3 others] -- Hematologic disorders and stroke / Cheryl Bushnell -- Migraine and stroke / Hans Christoph Diener, Tobias Kurth -- Cryptogenic stroke / Martin O'Donnell, Scott E. Kasner -- Cerebral venous thrombosis / José M. Ferro, Patrícia Canhão -- Ultrasonography / Michal Haršány, Georgios Tsivgoulis, Andrei V. Alexandrov -- Computed tomography-based evaluation of cerebrovascular disease / Imanuel Dzialowski [and 3 others] -- Magnetic resonance imaging of cerebrovascular diseases / Maarten G. Lansberg [and 4 others] -- Cerebral angiography / Ronald J. Sattenberg [and 4 others] -- Prehospital and emergency department care of the patient with acute stroke / Anna Gensic, Arthur Pancioli -- Intravenous thrombolysis / Wendy Brown, Patrick D. Lyden -- Antithrombotic therapy for treatment of acute ischemic stroke / Harold P. Adams Jr., Patricia H. Davis -- General stroke management and stroke units / Turgut Tatlisumak, Risto O. Roine -- Critical care of the patient with acute stroke / Marek Sykora, Silvia Schönenberger, Julian Bösel -- Pharmacologic modification of acute cerebral ischemia / Nicole R. Gonzales, James C. Grotta -- Treatment of "other" stroke etiologies / Scott E. Kasner, Brett L. Cucchiara -- Medical therapy of intracerebral and intraventricular hemorrhage / Darin B. Zahuranec, Lewis B. Morgenstern -- Rehabilitation and recovery of the patient with stroke / Bruce H. Dobkin -- Interventions to improve recovery after stroke / Steven C. Cramer -- Enhancing stroke recovery with cellular therapies / Sean I. Savitz, Kaushik Parsha -- Antiplatelet therapy for secondary prevention of stroke / Thalia S. Field [and 3 others] -- Secondary prevention of cardioembolic stroke / Karen Furie, Muhib Khan -- Conduct of stroke-related clinical trials / Adriana Pérez, Barbara C. Tilley -- Endovascular therapy of extracranial and intracranial occlusive disease / Maxim Mokin, Elad I. Levy -- Endovascular treatment of acute ischemic stroke / Reza Jahan, Jeffrey L. Saver -- Endovascular treatment of cerebral aneurysms / Ajay K. Wakhloo [and 3 others] -- Interventional therapy of brain and spinal arteriovenous malformations / Timo Krings, Sasikhan Geibprasert, Karel Ter Brugge -- Dural arteriovenous malformations / Javed Khader Eliyas, Issam A. Awad -- Surgery of anterior and posterior aneurysms / Mark J. Dannenbaum [and 4 others] -- Surgery for intracerebral hemorrhage / A. David Mendelow, Barbara A. Gregson --Intraventricular hemorrhage / J. Max Findlay -- Surgical management of cranial and spinal arteriovenous malformations / Jonathan Russin, Robert F. Spetzler -- Surgical cavernous malformations and venous anomalies / Najib E. El Tecle [and 7 others] -- Indications for carotid endarterectomy in patients with asymptomatic and symptomatic carotid stenosis / John A. Braca III [and 3 others] -- Extracranial to intracranial bypass for cerebral ischemia / David W. Newell, Marcelo D. Vilela, William J. Powers -- Decompressive craniectomy for infarction and hemorrhage / Hermann Neugebauer [and 3 others]
  • I. An introduction to the prokaryotic cell. The cellular system -- II. Cellular structures and their function. The plasma membrane -- Cell wall structure -- The cell wall matrix -- Capsules, pili, and internal structure -- III. Profiles of bacterial growth. Cell motion, sensing, and communication -- Cellular growth and reproduction -- Physiological basis for growth in extreme environments -- IV. Bioenergetics. Electron transport and coupled phosphorylation -- Transmembrane movement: mechanisms and examples -- V. Metabolic processes. Pathways of carbon flow -- Organization and cellular processing -- Metabolism of nitrogen and sulfur.
  • Modeling conformational flexibility and evolution of structure : RNA as an example / P. Schuster and P.F. Stadler -- Gene3D and understanding proteome evolution / J.G. Ranea ... [et al.] -- The evolution of the globins : we thought we understood it / A.M. Lesk -- The structurally constrained neutral model of protein evolution / U. Bastolla ... [et al.] -- Towards unifying protein evolution theory / N.V. Dokholyan and E.I. Shakhnovich -- A twenty-first century view of evolution : genome system architecture, repetitive DNA, and natural genetic engineering / J.A. Shapiro -- Genomic changes in bacteria : from free-living to endosymbiotic life / F.J. Silva ... [et al.] -- Molecular phylogenetics : mathematical framework and unsolved problems / X. Xia -- Phylogenetics and computational biology of multigene families / P. Liò, M. Brilli and R. Fani -- SeqinR 1.0-2 : a contributed package to the R project for statistical computing devoted to biological sequences retrieval and analysis / D. Charif and J.R. Lobry -- Evolutionary genomics of gene expression / I.K. Jordan and L. Mariño-Ramírez -- From biophysics to evolutionary genetics : statistical aspects of gene regulation / M. Lässig -- Drift and selection in evolving interacting systems / T. Ohta -- Adaptation in simple and complex fitness landscapes / K. Jain and J. Krug -- Genetic variability in RNA viruses : consequences in epidemiology and in the development of new strategies for the extinction of infectivity / E. Lázaro.
  • Bioinformatics in membrane protein analysis / Bengt Persson -- Prokaryotic membrane transport proteins / Joanne Clough ... [et al.] -- Membrane protein production strategies for structural genomics / Said Eshaghi and Par Nordlund -- Refolding of membrane proteins for large-scale production / Hans Kiefer, Thomas Ostermann, Monika Bahner -- Crystallization of membrane proteins / Alastair T. Gardiner, June Southall, and Richard J. Cogdell -- Signaling through membrane proteins / J. Robert Bostwick and Deborah S. Hartman -- Expression of membrane proteins in yeasts / Christoph Reinhart, Christoph Krettler -- Expression of functional membrane proteins in the baculovirus-insect cell system / Giel J.C.G.M. Bosman and Willem J. de Grip -- Expression of membrane proteins in mammalian cells / Kenneth Lundstrom -- Solubilization and purification of membrane proteins / Bernadette Byrne and Mika Jormakka -- Fluorescent labelling of membrane proteins in living cells / Ruud Hovius ... [et al.] -- Membrane protein NMR / Xiang-Qun (Sean) Xie -- Miniaturization of structural biology technologies--from expression to biophysical analyses / Enrique Abola, Peter Kuhn, and Raymond C. Stevens -- Electron microscopy and atomic force microscopy of reconstituted membrane proteins / Andreas Engel -- -- Structural genomics networks for membrane proteins / Kenneth Lundstrom -- Molecular modelling of membrane proteins / Slawomir Filipek and Anna Modzelewska -- Towards structural bases for GPCR ligand-binding / Sabrina A. Beretta ... [et al.].
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    Bioinformatics in membrane protein analysis / Bengt Persson -- Prokaryotic membrane transport proteins / Joanne Clough ... [et al.] -- Membrane protein production strategies for structural genomics / Said Eshaghi and Pär Nordlund -- Refolding of membrane proteins for large-scale production / Hans Kiefer, Thomas Ostermann, Monika Bähner -- Crystallization of membrane proteins / Alastair T. Gardiner, June Southall, and Richard J. Cogdell -- Signaling through membrane proteins / J. Robert Bostwick and Deborah S. Hartman -- Expression of membrane proteins in yeasts / Christoph Reinhart, Christoph Krettler -- Expression of functional membrane proteins in the baculovirus-insect cell system / Giel J.C.G.M. Bosman and Willem J. de Grip -- Expression of membrane proteins in mammalian cells / Kenneth Lundstrom -- Solubilization and purification of membrane proteins / Bernadette Byrne and Mika Jormakka -- Fluorescent labelling of membrane proteins in living cells / Ruud Hovius ... [et al.] -- Membrane protein NMR / Xiang-Qun (Sean) Xie -- Miniaturization of structural biology technologies--from expression to biophysical analyses / Enrique Abola, Peter Kuhn, and Raymond C. Stevens -- Electron microscopy and atomic force microscopy of reconstituted membrane proteins / Andreas Engel -- -- Structural genomics networks for membrane proteins / Kenneth Lundstrom -- Molecular modelling of membrane proteins / Slawomir Filipek and Anna Modzelewska -- Towards structural bases for GPCR ligand-binding / Sabrina A. Beretta ... [et al.].
  • Complex I (NADH:ubiquinone oxidoreductase) is the first and largest enzyme of the respiratory chain in mitochondria and plays a central role in cellular energy production. Complex I dysfunction has been implicated in many human neurodegenerative diseases, including Parkinson's. Mutations in complex I subunits are among the most common human genetic disorders known. Until recently, in the absence of structural information, complex I was the least understood enzyme of the respiratory chain. The mechanism by which it couples electron transfer between NADH and quinone to the translocation of protons across the membrane was a complete enigma. Recent years have been marked by spectacular progress in the elucidation of complex I's structure, finally allowing the interpretation of a wealth of data accumulated in about 50 years since the discovery of the enzyme. Understanding of the mechanism of this large molecular machine, involving long-range conformational changes, is beginning to emerge. This book is the first devoted entirely to complex I. It contains chapters written by leaders in the field, covering a wide range of topics from the structure of the complex, properties of its many redox centers, subunit composition, mutagenesis studies, evolution of the enzyme and on to the current understanding of the coupling mechanism and the molecular basis for human pathologies. Features: - Concise and authoritative review of current state-of-the-art in research on respiratory complex I - The first book entirely devoted to complex I, a central enzyme in bioenergetics - Recent breakthroughs in structure elucidation finally allow understanding of the mechanism - Mutations leading to common and severe human disorders are discussed.
  • Target selection for structural genomics : an overview / Russell L. Marsden and Christine A. Orengo -- A general target selection method for crystallographic proteomics / Gautier Robin ... [et al.] -- Target selection : triage in the structural genomics battlefield / James Raftery -- Data management in structural genomics : an overview / Sabrina Haquin ... [et al.] -- Data deposition and annotation at the worldwide protein data bank / Shuchismita Dutta ... [et al.] -- Prediction in protein disorder / Zsuzsanna Dosztányi and Peter Tompa -- Protein domain prediction / Helgi Ingolfsson and Golan Yona -- Protein structure modeling with MODELLER / Narayanan Eswar ... [et al.] -- High throughput cloning with restriction enzymes / Volker Sievert, Asgar Ergin, and Konrad Bussow -- Automated recombinant protein expression screening in Escherichia coli / Didier Busso ... [et al.] -- From no expression to high-level soluble expression in Escherichi coli by screening a library of the target proteins with randomized N-termini / Kyoung Hoon Kim ... [et al.] -- Application of high-throughput methodologies to the expression of recombinant proteins in E. coli / Yoav Peleg and Tamar Unger -- A high throughput platform for eukaryotic genes / Yunjia Chen ... [et al.] -- High throughput production of recombinant human proteins for crystallography / Opher Gileadi ... [et al.] -- Assembly of protein complexes by coexpression in prokaryotic and eukaryotic hosts : an overview / Anastassis Perrakis and Christophe Romier -- Cell-free protein synthesis for analysis by NMR spectroscopy / Margit A. Apponyi ... [et al.] -- A medium or high throughput protein refolding assay / Nathan P. Cowieson ... [et al.] -- Structural proteomics of membrane proteins : a survey of published techniques and design of a rational high throughput strategy / Melissa Swope Willis and Christopher M. Koth -- Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering / Joanne E. Nettleship ... [et al.] -- High throughput methods for analyzing transition metals in proteins on a microgram scale / Anelia Atanassova, Martin Högbom, and Deborah B. Zamble -- High throughput screening of purified proteins for enzymatic activity / Michael Proudfoot ... [et al.] -- Strategies for improving crystallization success rates / Rebecca Page -- Protein crystallization in restricted geometry : advancing old ideas for modern times in structural proteomics / Joseph D. Ng, Raymond C. Stevens, and Peter Kuhn -- Fluorescence approaches to growing macromolecule crystals / Marc Pusey, Elizabeth Forsythe, and Aniruddha Achari -- Efficient macromoleular crystallization using microfluidics and randomized design of screening reagents / Andrew P. May and Brent W. Segelke -- Increasing protein crystallization screening success with heterogeneous nucleating agents / Anil S.Thakur ... [et al.] -- High throughput pH optimization of protein crystallization / Ran Meged, Orly Dym, and Joel L. Sussman -- Automated structure solution with the PHENIX suite / Peter H. Zwart ... [et al.] -- NMR screening for rapid protein characterization in structural proteomics / Justine M. Hill -- Microcoil NMR spectroscopy : a novel tool for biological high throughput NMR spectroscopy / Russell E. Hopson and Wolfgang Peti -- Protein structure determination using a combination of cross-linking, mass spectrometry, and molecular modeling / Dmitri Mouradov ... [et al.] -- Structural genomics of minimal organisms : pipeline and results / Sung-Hou Kim ... [et al.] -- Structural genomics of pathogenic protozoa : an overview / Erkang Fan ... [et al.] -- High throughput crystallography at SGC Toronto : an overview / Alexey Bochkarev and Wolfram Tempel -- The structural biology and genomics platform in Strasbourg : an overview / Didier Busso, Jean-Claude Thierry, and Dino Moras -- Bacterial structural genomics initiative : overview of methods and technologies applied to the process of structure determination / Miroslaw Cygler ... [et al.] -- High-throughput protein production and crystallization at NYSGXRC / Michael J. Sauder ... [et al.] -- Overview of the pipeline for structural and functional characterization of macrophage proteins at the University of Queensland / Weining Meng ... [et al.] -- Structural genomics of the bacterial mobile metagenome : an overview / Andrew Robinson ... [et al.].
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  • Principles of protein structure and function -- A brief history of protein disorder -- Indirect techniques for recognizing and characterizing protein disorder -- Hydrodynamic techniques -- Spectroscopic techniques for characterizing disorder -- Nuclear magnetic resonance -- Proteomic approaches for the identification of IDPs -- IDPs under conditions approaching in vivo -- Prediction of disorder -- Structure of IDPs -- Biological processes enriched in disorder -- Molecular functions of disordered proteins -- Evolution and prevalence of disorder -- Extension of the structure-function paradigm -- Structural disorder and disease.
  • Part I. Structure and ligands of NCAM. -- Structural biology of NCAM / Vladislav Soroka, Christina Kasper, Flemming M. Poulsen. -- Extracellular protein interactions mediated by the neural cell adhesion molecule, NCAM: heterophilic interactions between NCAM and cell adhesion molecules, extracellular matrix proteins, and viruses / Janne Nielsen, Nikolaj Kulahin, Peter S. Walmod. -- Intracellular (intracelluar) ligands of NCAM / Bettina Buttner, Rudiger horstkorte. -- Role of ATP in the regulation of NCAM function / Martin V. Hubschmann, Galina Skladchikova. -- Part II. NCAM and plysialic acid. -- Polysialylation of NCAM / Herbert Hildebrandt, Martina Muhlenhoff, Rita Gerardy-Schahn. -- Structural basis for the polysialylation of the neural cell adhesion molecule / Karen J. Colley. -- Role of PSA-NCAM in adult neurogenesis / Eduardo Gascon, Laszlo Vutskits, Jozsel Zoltan Kiss. -- Use of PSA-NCAM in repair of the central nervous system / Abderrahman El Maarouf, Urs Rutishauser. -- Part III. NCAM-mediated signal transduction. -- Signaling pathways involved in NCAM-induced neurite outgrowth / Dorte Kornerup Ditlevsen, Kateryna Kolkova. -- Role of the growth-associated protein GAP-43 in NCAM mediated neurite outgrowth / Irina Korshunova, Mark Mosevitski. -- Neural cell adhesion molecule NCAM and lipid rafts / Gro Klitgaard Povlsen, Dorte Kornerup Ditlevsen. -- Neural cell adhesion molecule and epidermal growth factor receptor: signaling crosstalk / Gro Klitgaard Polvsen. -- Part IV. NCAM metabolism. -- Biosynthesis of NCAM / Kateryna Kolkova. -- Soluble NCAM / Thomas Secher. -- Part V. NCAM, synapses, emotions, and memory. -- Role of NCAM in spine dynamics and synaptogenesis / D. Muller, P. Mendez, M. DeRoo, P. Klauser, S. Steen, and L. Poglia. -- NCAM in long-term potentiation and learning / Barbara P. Hartz, Lars Christian B. Roon. -- Role of NCAM in emotion and learning / Lisa Conboy, Reto Bisaz, Kamila Markram, Carment Sandi. -- Part VI. NCAM in disease. -- NCAM in neuropsychiatric and neurodegenerative disorders / Leann H. Brennaman, Patricia F. Maness. -- Neural cell adhesion molecule in cancer: expression and mechanisms / Silvia Zecchini, Ugo Caallaro. -- Part VII. Pharmacology of NCAM: NCAM mimetics. -- NCAM mimetic peptides: an update / Vladimir Berezin, Elisabeth Bock. -- Synthetic NCAM-derived ligands of the fibroblast growth factor receptor / Stine maria Hansen, Shizhong Li, Elisabeth Bock, Vladimir Berezin. -- Dendritic spine and synapse morphological alterations induced by neural cell adhesion molecule mimetic / Michael Stewart, Victor Popov, Nikolai Medvedev, Paul Giabbon, Nicola Corbett, Igor Kraev, Heather Davies. -- Part VIII. Orthologs and paralogs of NCAM. -- Fasciclin II: the NCAM ortholog in Drosophila melanogaster / Lars V. Kristiansen, Michael Hortsch. -- Neural cell adhesion molecule NCAM2/OCAM/RNCAM, a close relative to NCAM / Nikolaj Kulahin, Peter S. Walmod. -- Part IX. Conclusion. -- Honoring Dr. Elisabeth Bock / Vladimir Berezin.
  • This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdo
  • Chapter 1. Lipid structure -- Chapter 2. The mesomorphic phase behavior of lipid bilayers -- Chapter 3. Lipid bilayer interdigitation -- Chapter 4. The dynamics of membrane lipids -- Chapter 5. Nonlamellar lipid phases -- Chapter 6. The forces between interacting bilayer membranes and the hydration of phospholipid assemblies -- Chapter 7. The roles of cholesterol in the biology of cells -- Chapter 8. Lipid membrane fusion -- Chapter 9. Membrane rafts -- Chapter 10. Passive and facilitated transport -- Chapter 11. Membrane protein dynamics: rotational dynamics -- Chapter 12. Translational diffusion of membrane proteins -- Chapter 13. Inorganic anion transporter AE1 -- Chapter 14. The structures of G-protein coupled receptors -- Chapter 15. Role of membrane lipids in modulating the activity of membrane-bound enzymes -- Chapter 16. Viral fusion mechanisms.
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  • The Mastigont System in Trichomonads / Marlene Benchimol -- Subpellicular Microtubules in Apicomplexa and Trypanosomatids / Wanderley de Souza and Marcia Attias -- Flagellum Structure and Function in Trypanosomes / Johanna Buisson and Philippe Bastin -- The Flagellar Pocket of Trypanosomatids: A Critical Feature for Cell Morphogenesis and Pathogenicity / Paul G. McKean and Keith Gull -- Reservosomes of Trypanosoma cruzi / Narcisa Leal Cunha-e-Silva, Celso Sant'Anna, Miria G. Pereira and Wanderley de Souza -- Megasomes in Leishmania / Diane McMahon-Pratt, Tania Ueda-Nakamura and Yara M. Traub-Csekö -- Organelles and Trafficking in Entamoeba histolytica / Sherri S. Smith and Nancy Guillen -- Secretory Organelles in Apicomplexa / Jean François Dubremetz -- Secretory Events During Giardia Encystation / Fernando D. Rivero, Dana Müller and Hugo D. Lujan -- The Remarkable Mitochondrion of Trypanosomes and Related Flagellates / Julius Lukeš, Hassan Hashimi, Zdeněk Verner and Zdeňka Čičová -- The Apicoplast: An Ancient Algal Endosymbiont of Apicomplexa / Swati Agrawal, Sethu Nair, Lilach Sheiner and Boris Striepen -- The Glycosome of Trypanosomatids / Fred R. Opperdoes -- Calcium Homeostasis and Acidocalcisomes in Trypanosoma cruzi / Paul Ulrich, Roxana Cintrón and Roberto Docampo.
  • Native purification and analysis of long RNAs -- Characterizing RNA excited states using NMR relaxation -- Quantifying nucleic acid ensembles with x-ray scattering interferometry -- 2-aminopurine fluroescence as a probe of local RNA structure and dynamics and global folding -- Mod-seq: a high-throughput method for probing RNA secondary structure -- Reproducible analysis of sequencing-based RNA structure probing data with user-friendly tools -- Computational methods for RNA structure validation and improvement -- Structures of large RNAs and RNA-protein complexes: toward structure determination of riboswitches -- One, two, three, four! How multiple RRMs read the genome sequence -- Combining NMR and EPR to determine structures of large RNAs and protein-RNA complexes in solution -- Structural analysis of protein-RNA complexes in solution using NMR paramagnetic relaxation enhancements -- Resolving individual components in protein-RNA complexes using small-angle x-ray scattering experiments -- Small-anlge neurtron scattering for structural biology of protein-RNA complexes -- Strudying RNA-protein interactions of Pre-mRNA complexes by mass spectrometry -- RNA bind-n-Seq: measuring the binding affinity landscape of RNA-binding proteins -- Using molecular simulation to model high-resolution Cryo-EM reconstructions -- In vitro reconstitution and crystallization of Cas9 endonuclease bound to a guide RNA and a DNA target -- Single-molecule pull-down FRET to dissect the mechanisms of biomolecular machines -- Single-molecule imaging of RNA splicing in live cells.
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    I. Untersuchung über das Rachitisvorkommen in einem norwegischen Binnental.
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    v. 1. Evaluation of treatments.--v. 2. Research on patients, treatments, and outcomes.--v. 3. Further studies of drug users, treatment typologies, and assessment of outcomes during treatment in DARP.--v. 4. Evaluation of treatment outcomes for 1971-1972 DARP admission cohort.--v. 5. Evaluation of treatment outcomes for 1972-1973 DARP admission cohort.
  • This volume systematically reviews the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as oxidative stress, in the pathology of Alzheimer's disease. It describes the most current diagnostic tools, laboratory methods and technology, and suggests ways of prevention and treatment to emphasize the concept of the bench-to-bedside approach. Studies on Alzheimer's Disease provides thorough coverage of emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents, and several more relevant aspects. In addition, this book promotes the concept of using biomarkers representative of oxidative stress reactions and free-radical damage, as well as describing the effects of antioxidants in treating disease in clinical trials. This content is invaluable to both researchers studying the development of and clinicians treating patients with a diagnosis of Alzheimer's Disease.
  • Joint diseases are a major public health concern. Reactive oxygen species are mediators in pathways associated with joint tissue injury. Oxidative Stress in Applied Basic Research and Clinical Practice: Studies on Arthritis and Joint Disorders provides background to understanding the role of reactive oxygen species in joint diseases, as well as therapeutic strategies for their regulation. International experts discuss recent advances on experimental and clinical data focused on free radical-mediated mechanisms of disease. The book also addresses the protective role of antioxidants against the insult of reactive oxygen species in rheumatic diseases.
  • The Evolving Concept of Oxidative Stress / Denise de Castro Fernandes, Diego Bonatto and Francisco R.M. Laurindo -- Mechanisms of Redox Signaling in Cardiovascular Disease / Rebecca L. Charles, Joseph R. Burgoyne and Philip Eaton -- Reactive Oxygen and Nitrogen Species in Cardiovascular Differentiation of Stem Cells / Heinrich Sauer and Maria Wartenberg -- Reactive Oxygen Species (ROS) and the Sensory Neurovascular Component / Rabea Graepel, Jennifer Victoria Bodkin and Susan Diana Brain -- Mitochondrial Reactive Oxygen Species in Myocardial Pre- and Postconditioning / Ariel R. Cardoso, Bruno B. Queliconi and Alicia J. Kowaltowski -- Coenzyme Q9/Q10 and the Healthy Heart / Samarjit Das, Somak Das and Dipak K. Das -- Oxidative and Proteolytic Stress in Homocysteine-Associated Cardiovascular Diseases / Karni S. Moshal, Munish Kumar, Neetu Tyagi, Paras Kumar Mishra and Saumi Kundu, et al. -- Functional Studies of NADPH Oxidases in Human Vasculature / Tomasz J. Guzik -- Relationship of the CYBA Gene Polymorphisms with Oxidative Stress and Cardiovascular Risk / Guillermo Zalba and Javier Díez -- Redox-Related Genetic Markers of Cardiovascular Diseases / Christian Delles and Anna F. Dominiczak -- NADPH Oxidases and Blood-Brain Barrier Dysfunction in Stroke / Timo Kahles, Sabine Heumüller and Ralf P. Brandes -- Smoking-Induced Oxidative Stress in the Pathogenesis of Cardiovascular Diseases / David Bernhard -- Oxidative Stress in Vascular Aging / Anna Csiszar and Zoltan Ungvari -- Oxidative Stress and Cardiovascular Disease in Diabetes Mellitus / Divya Gupta, Kathy K. Griendling and W. Robert Taylor -- Reactive Oxygen Species, Oxidative Stress, and Hypertension / Rhian M. Touyz, Andreia Chignalia and Mona Sedeek -- Peripartum Cardiomyopathy: Role of STAT-3 and Reactive Oxygen Species / Denise Hilfiker-Kleiner, Arash Haghikia and Andres Hilfiker -- Oxidative Stress and Inflammation after Coronary Angiography / Raymond Farah -- Oxidative Stress in Cardiac Transplantation / Galen M. Pieper and Ashwani K. Khanna -- Oxidative Stress and Atrial Fibrillation / Ali A. Sovari and Samuel C. Dudley -- Oxidative Stress and the Antioxidative Capacity in Myocardial Infarction / Yao Sun -- Oxidative Stress and Redox Signalling in Cardiac Remodelling / Min Zhang, Alex Sirker and Ajay M. Shah -- Oxidative Stress and Cardiovascular Fibrosis / Subramaniam Pennathur, Louise Hecker and Victor J. Thannickal -- Oxidative Risk Factors for Cardiovascular Disease in Women / Manuela Gago-Dominguez, Xuejuan Jiang and Jose Esteban Castelao -- Protective Effects of Food on Cardiovascular Diseases / Alfonso Giovane and Claudio Napoli -- Novel Synthetic Antioxidants and Nitrated Lipids: From Physiology to Therapeutic Implications / Gloria V. López and Homero Rubbo -- Thioredoxin in the Cardiovascular System-Towards a Thioredoxin-Based Antioxidative Therapy / Cameron World and Bradford C. Berk -- The Protective Effect of Melatonin on the Heart / Amanda Lochner -- Exercise-Induced Cardioprotection: Overview with an Emphasis on the Role of Antioxidants / Karyn L. Hamilton and John C. Quindry -- Antioxidative Properties of Statins in the Heart / Oliver Adam and Ulrich Laufs.
  • Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of -crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina. A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.
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  • Evidence-based information plays a critical role in clinical practice decisions. Secondary sources are often unreliable; it.s up to the student, then, to critically assess peer-reviewed research literature. Using a highly structured yet accessible method, this text teaches students to critically analyze research from primary sources. Step-by-step approach. learn to recognize a meaningful study, clues to potential study flaws, and ways to apply solid evidence in clinical practice. Simple 6-point framework. learn to evaluate studies in terms of the authors trademark mnemonic device, M.A.A.R.I.E. (Methods, Assignment, Assessment, Results, Interpretation and Extrapolation). Unique Learning Aids - question checklists, real-world scenarious, flaw-catching exercises and more help to make complex concepts easy to grasp.
  • "This pocket-sized book is a quick-reference practical guide for physicians who deal with patients with subarachnoid hemorrhage or intracranial aneurysms outside the hospital. It describes briefly the epidemiology of subarachnoid hemorrhage, the early recognition and clinical course, and in more depth the aftercare, residual symptoms and deficits. The prognosis and management in the long term are discussed in detail. It also provides information on the counselling and treatment of patients with unruptured intracranial aneurysms. Subarachnoid Hemorrhage in Clinical Practice is aimed at general practitioners and family physicians and will also be informative for other specialists such as rehabilitation physicians, nursing home physicians, and physicians working for health insurance companies. It may also be of interest to patients, relatives, and paramedics."--Back cover.
  • Defines the functional neuroanatomy of cortical-subcortical circuitries and establishes that since structure is related to function, what the basal ganglia and cerebellum do for movement they also do for cognition and emotion. This book also examines neuropsychological assessment.
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    There are 9 vols. in the Subject section; 5 vols. in the Biographical section and 4 vols. in the Topographical section. This series reproduces the card subject catalog of the library and includes a cumulation of Current Work in the History of Medicine (No. 6451.1). Material is included until 1977.
  • Subjective well-being refers to how people experience and evaluate their lives and specific domains and activities in their lives. This information has already proven valuable to researchers, who have produced insights about the emotional states and experiences of people belonging to different groups, engaged in different activities, at different points in the life course, and involved in different family and community structures. Research has also revealed relationships between people's self-reported, subjectively assessed states and their behavior and decisions. Research on subjective well-being has been ongoing for decades, providing new information about the human condition. During the past decade, interest in the topic among policy makers, national statistical offices, academic researchers, the media, and the public has increased markedly because of its potential for shedding light on the economic, social, and health conditions of populations and for informing policy decisions across these domains. Subjective Well-Being: Measuring Happiness, Suffering, and Other Dimensions of Experience explores the use of this measure in population surveys. This report reviews the current state of research and evaluates methods for the measurement. In this report, a range of potential experienced well-being data applications are cited, from cost-benefit studies of health care delivery to commuting and transportation planning, environmental valuation, and outdoor recreation resource monitoring, and even to assessment of end-of-life treatment options. Subjective Well-Being finds that, whether used to assess the consequence of people's situations and policies that might affect them or to explore determinants of outcomes, contextual and covariate data are needed alongside the subjective well-being measures. This report offers guidance about adopting subjective well-being measures in official government surveys to inform social and economic policies and considers whether research has advanced to a point which warrants the federal government collecting data that allow aspects of the population's subjective well-being to be tracked and associated with changing conditions.
  • I. Foundations -- Historical perspectives / David F. Musto -- Epidemiology / Charles Winick and R.L. Norman -- U.S. federal drug policy / Mathea Falco -- II. Determinants of substance abuse and dependence -- Genetic factors in the risk for substance use disorders / Show W. Lin and Robert M. Anthenelli -- Brain-reward mechanisms / Eliot L. Gardner -- Psychodynamics / Edward J. Khantzian, Lance Dodes, Nancy M. Brehm -- Sociocultural issues / Bruce D. Johnson and Andrew Golub -- III. Substances of abuse -- Alcohol: neurobiology / Stephen L. Boehm II, C. Fernando Valenzuela, R. Adron Harris -- Alcohol: clinical aspects / Bankole A. Johnson and Nassima Ait-Daoud -- Opiates: neurobiology / Eric J. Simon -- Opiates: clinical aspects / Clifford M. Knapp, Domenic A. Ciraulo, and Jerome Jaffe -- Cocaine and crack: neurobiology / Martin Repetto and Mark S. Gold -- Cocaine and crack: clinical aspects / Mark S. Gold and William S. Jacobs -- The Neurobiology of marijuana / Sandra P. Welch -- Marihuana: clinical aspects / Lester Grinspoon, James B. Bakalar, and Ethan Russo -- Amphetamines and other stimulants / George R. King and Everett H. Ellinwood, Jr. -- Sedative-hypnotics / Donald R. Wesson, David E. Smith, Walter Ling, and Richard B. Seymour -- Hallucinogens / Robert N. Pechnick and J. Thomas Ungerleider -- Phencyclidine (PCP) / Stephen R. Zukin, Zili Sloboda, and Daniel C. Javitt -- Inhalants / Charles W. Sharp and Neil L. Rosenberg -- Designer drugs / John P. Morgan -- MDMA / Charles S. Grob and Russell E. Poland -- Nicotine / Joy M. Schmitz and Katherine A. DeLaune -- Caffeine / Laura M. Juliano and Roland R. Griffiths -- Anabolic-androgenic steroids / Elyse R. Eisenberg and Gantt P. Galloway -- Prescription opiate abuse / Walter Ling, Donald R. Wesson, and David E. Smith -- IV. Related compulsive and addictive behaviors -- Eating disorders / Mark S. Gold Jodi Star -- Pathologic gambling / Sheila B. Blume and Hermano Tavares -- Addiction and cults: synthesizing a model for treating ex-members / Ron Burks -- Sexual addiction: nosology, diagnosis, etiology, and treatment / Aviel Goodman -- Internet/computer addiction / Zebulon Taintor -- Collecting, accumulation, and hoarding: acquisitions and their discontents / David A. Halperin and Jane Glick -- V. Evaluation and early treatment -- Diagnosis and classification: DSM-IV-TR and ICD-10 / John Cacciola and George E. Woody -- Diagnostic laboratory: screening for drug abuse / Karl G. Verebey, Gerard Meenan, and Betty J. Buchan -- VI. Treatment approaches -- Detoxification / Grace Chang and Thomas R. Kosten -- Alcoholics Anonymous / Edgar P. Nace -- Alternative support groups / Arthur T. Horvath -- The therapeutic community / William B. O'Brien and Fernando B. Perfas -- Methadone maintenance / Joyce H. Lowinson, Ira Marion, Herman Joseph, John Langrod, Edwin A Salsitz, J. Thomas Payte, and Vincent P. Dole -- Buprenorphine for the treatment of opioid addiction / Paul J. Fudala and Charles P. O'Brien -- Alternative pharmacotherapies for opioid addiction / Paul J. Fudala, Robert A. Greenstein, and Charles P. O'Brien -- Individual psychotherapy / Bruce J. Rounsaville, Kathleen M. Carroll, and Sudie Back -- Group therapy with outpatients / Arnold M. Washton -- Family/couples approaches to treatment engagement and therapy / M. Duncan Stanton and Anthony W. Heath -- The role of coercion in drug treatment / Sally L. Satel and David J. Farabee -- Treatment in prisons and jails / Roger H. Peters, Charles O. Matthews, and Joel A. Dvoskin -- Cognitive and behavioral therapies / Lisa M. Najavits, Bruce S. Liese, and Melanie S. Harned -- Network therapy / Marc Galanter -- Acupuncture / Ji-Sheng Han, Alan I. Trachtenberg, and Joyce H. Lowinson -- Faith-based approaches / John G. Langrod, John Muffler, James Abel, James T. Richardson, Eugenia Curet, Herman Joseph, and Pedro Ruiz -- Relapse prevention / Dennis C. Daley and G. Alan Marlatt -- Evaluation and outcome of treatment / Robert L. Hubbard -- VII. Management of associated medical conditions -- Maternal and neonatal effects of alcohol and drugs / Loretta P. Finnegan and Stephen R. Kandall -- Medical complications of drug use / Marc N. Gourevitch and Julia H. Arnsten -- Acute and chronic pain / Russell K. Portenoy, Richard Payne, and Steven D. Passik -- Substance use disorders in individuals with co-occurring psychiatric disorders / Sylvia J. Dennison -- VIII. HIV Infection and AIDS -- Epidemiology and emerging public health perspectives / Don C. Des Jarlais, Holly Hagan, and Samuel R. Friedman -- HIV-related medical complications and treatment / Chinazo O. Cunningham and Peter A. Selwyn -- Neuropsychiatric aspects of HIV- infection / Francisco Fernandez, Jorge Maldonado, and Pedro Ruiz -- Psychosocial issues of HIV/AIDS among drug users in treatment / James L. Sorensen, Nancy A. Haug, and Steven L. Batki -- IX. Life cycle -- Children of substance-abusing parents / Patti Juliana and Carolyn Goodman -- Adolescents / Andres J. Pumariega, Mark D. Kilgus, and Leonardo Rodriguez -- The elderly / Steven R. Gambert and Charles R. Albrecht III -- X. Women's issues -- Alcohol and women / Sheila B. Blume and Monica L. Zilberman -- Drugs and women / Monica L. Zilberman and Sheila B. Blume -- Women's research and policy issues / Marsha Rosenbaum and Sheigla Murphy -- XI. Ethnic populations -- African Americans: epidemiology, prevention, and treatment issues / Charles Madray, Lawrence S. Brown, Jr., and Beny J. Primm -- Hispanic Americans / Pedro Ruiz and John G. Langrod -- Asian Americans and Pacific Islanders / John W. Tsuang -- Alcohol use among American Indians and Alaskan Natives / Edward F. Foulks -- XII. Other populations -- Gays, lesbians, and bisexuals / Robert Paul Cabaj -- The homeless / Herman Joseph and John Langrod -- Disability and rehabilitation issues / Allen W. Heinemann and Purva H. Rawal -- Physicians and other health professionals / G. Douglas Talbott and Philip O. Wilson -- New immigrants and refugees / Joseph Westermeyer -- XIII. Models of prevention -- School-based programs / Gilbert J. Botvin and Kenneth W. Griffin -- Harm reduction: pragmatic drug policies for public health and safety / Ernest Drucker, Ethann Nadelman, Robert G. Newman, Alex Wodak, Jennifer McNeely, Kasia Malinowska-Semprucht, David Marsh, Martin Schechter, Bruna Brands, and Eugene Oscapella -- Church, family, and community in the prevention and treatment of addiction among African Americans / Ronald Hopson and William B. Lawson -- The public health approach to the prevention of substance abuse / Steven Jonas -- XIV. Training and education -- Medical education in substance abuse: the acquisition of knowledge, attitudes, and skills / John N. Chappel -- Education and training of clinical personnel / David A. Deitch, Igor Koutsenok, and Karin Marsolais -- Forensics / Milton Earl Burglass and Stuart Gitlow -- The role of neuropsychological assessment in forensic addiction / Ari D. Kalechstein, Wilfred G. van Gorp, and Garrett J. Zelen -- XV. Policy issues -- A new era for methadone advocacy / Joycelyn Woods, Walter Ginter, and Tony Scro -- The workplace / Paul F. Engelhart and Linda Barlow -- Treatment for alcohol and drug dependence: history, workforce, organization, financing, and emerging policies / Dennis McCarty and Howard H. Goldman -- Legal aspects of confidentiality of patient information / Margaret K. Brooks -- Clinical and societal implications of drug legalization / Herbert D. Kleber and James A. Inciardi -- Index.
  • "Stay up to date with the latest substance abuse treatments and modes of intervention with The Substance Abuse Handbook, 2e. The editors are both nationally recognized clinicians, and provide authoritative, clinically oriented information on the subject of substance use, abuse, and dependence, with an emphasis on diagnosis, treatment, and prevention.You'll find focused, expert information on every aspect of the field, including etiological factors; substances of abuse; compulsive and addictive behaviors; evaluation and diagnostic classification; treatment modalities, management of associated medical conditions; substance abuse in youth and the elderly; women's issue; special groups and settings; models of prevention; training and education; and policy issues. Succinctly presenting the most clinically relevant information from Lowinson and Ruiz's Substance Abuse, 5e, this concise, portable handbook is a must-have reference for anyone involved directly or indirectly in the addiction field.New to This Edition Find the practical information you need fast with this edition's focused coverage of basic science and greater emphasis on clinical concerns. Stay current with the latest information in the field, including changes reflecting the release of DSM-5. Access updated information in key topic areas, including "Special Populations," "Special Settings," and "Models of Prevention."-- Provided by publisher.
  • This book is written for any clinician who encounters substance abuse in a patient and wonders what to do. Experts from a cross-section of specialties and health professions provide up-to-date, evidence-based guidance on how non-expert clinicians can recognize, understand, and approach the management of substance abuse in their patients. They detail the range of treatments available and whether and how they work. The central importance of using a carefully selected multimodal approach that is tailored to the individual patient is emphasized throughout and illustrated in case scenarios from actual clinical practice.
  • The need for college recovery services / Richard P. Wiebe, H. Harrington Cleveland, and Kitty S. Harris -- Collegiate recovery communities : what they are and how they support recovery / Kitty S. Harris, Amanda Baker, and H. Harrington Cleveland -- Facilitating identity development in collegiate recovery : an Eriksonian perspective / Matthew Russell, H. Harrington Cleveland, and Richard P. Wiebe -- Characteristics of collegiate recovery community members / H. Harrington Cleveland, Amanda Baker, and Lukas R. Dean -- Maintaining abstinence in college : temptations and tactics / Richard P. Wiebe, H. Harrington Cleveland, and Lukas R. Dean -- Daily lives of young adult members of a collegiate recovery community / H. Harrington Cleveland and Allison Groenendyk -- How membership in the collegiate recovery community maximizes social support for abstinence and reduces risk of relapse / H. Harrington Cleveland, Richard P. Wiebe, and Jacquelyn D. Wiersma -- Building support for recovery into an academic curriculum : student reflections on the value of staff run seminars / Ann M. Casiraghi and Miriam Mulsow -- Establishing college-based recovery communities : opportunities and challenges encountered / Amanda Baker.
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  • Pt. 1. General principles of substance use disorders -- An initial approach -- Types of use -- The substance use disorders -- Screening techniques -- The first interview -- Outpatient logistics -- Laboratory studies -- Pt. 2. Substance review -- Alcohol -- Other sedatives -- Sedative detoxification -- Medications during sedative recovery -- Nicotine -- Stimulants -- Opiates/opioids -- Opioid detoxification -- Opioid maintenance programs -- Marijuana -- LSD -- Other drugs -- Substance-induced disorders -- Pt. 3. Substance use treatment -- Treatment settings -- Twelve step programs -- Prevention -- Who treats substance use? -- Treatment dilemmas -- Patient placement criteria -- Legal issues -- Spirituality / by Stanley E. Gitlow.
  • Introduction -- Cytology of the subthalamic nucleus -- Ontogeny of the subthalamic nucleus -- Topography of the rat, cat, baboon, and human subthalamic nucleus -- Connections of the subthalamic nucleus -- Nigro-subthalamic connections in rat.
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  • Academic surgeons play an essential role in advancing the field and improving the care of patients with surgical disease. As the Association for Academic Surgery (AAS) Fall Courses ( and international courses continue to evolve to address the rapidly expanding scope and complexity of academic surgery, there is a greater need for an accompanying textbook to supplement the material presented in the courses. Success in Academic Surgery: Basic Science is a unique and portable handbook that focuses on the basic and translational research. It includes new educational materials that are necessary to address not only the rapid evolution and rise of novel research methodologies in basic science and translational research, but also the changing environment for academic surgeons. Success in Academic Surgery: Basic Science is a valuable text for medical students, surgical residents, junior faculty and others considering a career in surgical research.
  • Building Your Clinical Trial Research Team -- Clinical Trials: Ensuring Quality and Standardization -- Statistics: Setting the Stage -- Clinical Trials: Handling the Data -- Data Safety Monitoring Boards -- Planning for Data Monitoring and Audits -- The Budget -- Regulatory Considerations in Human Subjects Research -- Publishing a Clinical Trial -- Device Versus Drug Clinical Trials: Similarities and Important Differences -- Defining the Study Cohort: Inclusion and Exclusion Criteria -- The History of Clinical Trials -- Ethics of Clinical Trials -- Trial Design: Overview of Study Designs (Phase I, II, III, IV, Factorial Design).
  • Success in Academic Surgery: Developing a Career in Surgical Education is a unique and portable handbook that offers careers advice and guidance to medical students, surgical residents, young faculty and others considering a career within surgical education. Surgical education is a rapidly expanding area of surgical research and career interest, and as the Association for Academic Surgery (AAS) fall courses ( and international courses offer more and more specialty tracking there is a greater need for an accompanying textbook to supplement the material presented in the courses. Success in Academic Surgery: Developing a Career in Surgical Education expands on some of the important issues related to surgical education highlighted in the AAS courses by addressing key areas such as how to acquire the skills necessary for success in this field, how to develop a research program in surgical education as well as offering guidance on applying for research grants, among other things.
  • Success in Academic Surgery: Health Services Research is a unique handbook which will help researchers and surgeons in obtaining National Institutes of Health funding and other grants, as well as breaking through the barriers to developing a career in academic surgery. Aimed at surgical residents and young surgical faculty, Success in Academic Surgery: Health Services Research is written by expert authors from around the world who are members of the Association for Academic Surgery, and it offers a practical and personal insight on working in academic surgery.
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    Introduction -- Internal medicine clerkship -- Surgery clerkship -- Pediatrics clerkship -- Psychiatry clerkship -- Obstetrics & gynecology clerkship -- Family medicine clerkship -- Patients -- The new rotation -- Admitting patients -- On call -- Laboratory tests -- Ancillary tests -- Attending rounds -- Oral case presentations -- Write-ups -- The outpatient setting -- Evaluations -- The written exam -- Rotation success -- Attendings -- Working as a team -- Giving talks.
  • Career management / Peggy A. Pritchard -- Continuing professional development / Christine Faerber and Anngienetta Johnson -- Training and working abroad / Mary Osborn -- Climbing the ladder / Ilene J. Busch-Vishniac -- Mentoring / Christine S. Grant -- Networking / Patricia Rankin and Joyce McCarl Nielsen -- Mental toughness / Peggy A. Pritchard -- Personal style / M. Elizabeth Cannon and Kathleen Sendall -- Communicating science / Christine Szymanski -- Time stress / Peggy A. Pritchard -- Balancing professional and personal life / Sarah E. Randolph ... [et al.] -- Transitions / Margaret Ann-Armour and Dorothy Tovell.
  • Targeting oncogenic drivers / Zhao, Y.; Adjei, A.A. (Buffalo, N.Y.) -- Successes and limitations of targeted cancer therapy in breast cancer / Curigliano, G.; Criscitiello, C. (Milan) -- Successes and limitations of targeted cancer therapy in colon cancer / Khne, C.-H. (Oldenburg) -- Successes and limitations of targeted cancer therapy in gastrointestinal stromal tumors / Casali, P.G. (Milano) -- Successes and limitations of targeted cancer therapy in lung cancer / Suda, K. (Osaka-Sayama/Fukuoka); Mitsudomi, T. (Osaka-Sayama) -- Successes and limitations of targeted cancer therapy in melanoma / Romano, R.; Michielin, O. (Lausanne) -- / successes and limitations of targeted cancer therapy in ovarian cancer / Damia, G. (Milan); Sessa, C. (Bellinzona) -- Successes and limitations of targeted therapies in renal cell carcinoma / Pracht, M.; Berthold, D. (Lausanne).
  • Building trust and communication -- Impacts : quality and financial -- Clinical documentation specialist : who is involved and what is the process? -- Clinical documentation specialist and education -- Collaboration with hospital case management -- Putting it all together -- Final thoughts.
  • Why write a grant? -- Becoming familiar with funding sources -- Developing your ideas for funding -- Common sections of proposals -- Strategies for effective writing -- Technical writing considerations -- Developing a budget -- Putting it all together to create a budget -- Technical considerations in budget development -- Four project structures -- Understanding the process of collaboration -- Forming a collaborative team -- Learning about your institution -- Electronic considerations -- Understanding the review process -- Responding to the proposal review -- A case study -- Welcome to the world of post-award -- More post-award considerations.
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    The application -- Specialty-specific information -- The basics -- Selection process -- The right fit -- Curriculum vitae (CV) -- Letters of recommendation -- Personal statement -- Dean's letter (MSPE) -- The audition elective -- The competitive edge -- Before the interview -- Interview questions -- The interview day -- After the interview -- Ranking residency programs -- International medical graduates.
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    Preparing to write -- Composing a first draft -- Visual support for the written word -- Visual support for the spoken word -- Revising to increase coherence -- Improving word choice, and syntax style -- Attending to grammar, numbers, and other mechanics -- The rest of the story.
  • "The authors draw on 50 years of experience, providing detailed step-by-step guidance designed to help students and researchers write and present scientific manuscripts more successfully through knowledge, practice, and an efficient approach."--Publisher description.
  • Why are some societies more successful than others at promoting individual and collective well-being? This book integrates recent research in social epidemiology with broader perspectives in social science to explore why some societies are more successful than others at securing population health. It explores the social roots of health inequalities, arguing that inequalities in health are based not only on economic inequalities, but on the structure of social relations. It develops sophisticated new perspectives on social relations, which emphasize the ways in which cultural frameworks as well as institutions condition people's health. It reports on research into health inequalities in the developed and developing worlds, covering a wide range of national case studies, and into the ways in which social relations condition the effectiveness of public policies aimed at improving health.
  • Medical overview of sudden in-custody deaths / Theodore C. Chan -- The nature of sudden custodial deaths / Darrell L. Ross -- Neck holds / Gary M. Vilke -- Positional and restraint asphyxia / Tom Neuman -- Restraint stress / Elizabeth A. Laposata -- The role of illicit drug use in sudden in-custody death / Aaron B. Schneir and Richard F. Clark -- Excited delirium / Charles V. Wetli -- Riot control agents, taser, and other less lethal weapons / Christian Sloane and Gary M. Vilke -- Case analysis of restraint deaths in law enforcement and corrections / Darrell L. Ross -- Deaths in custody investigations / Vincent Dimiao -- Liability and wrongful custodial deaths / Darrell L. Ross -- Administrative implications / Darrell L. Ross.
  • Sudden infant death syndrome (SIDS) is characterised by the sudden death of an infant that is not predicted by prior medical history and it is still responsible for a large percentage of infant mortalities. The exact causes have long remained unknown, though some risk factors such as including exposure to tobacco smoke, no breast feeding, and prone sleeping position, have been identified. However an analysis linking neurophysiological and neuropathological aspects in a prospective study of SIDS suggests that one of the causes of SIDS is arousal deficiency. This unique book provides the latest, comprehensive information on SIDS research from epidemiology to physiology.
  • The article is a summary of a study that was "part of a larger program of research by The Carnegie Foundation for the Advancement of Teaching on preparation for the professions"--Website.
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    "The goal of this volume is to comprehensively cover a highly readable, updated and extended, overview on our present knowledge of positive and negative effects of UV-exposure, with a focus on vitamin D and skin cancer. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in endocrinology, epidemiology, histology, photobiology, immunology, cytogenetics and molecular pathology to new concepts for prophylaxis and treatment. Experts in the field as well as health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of the second edition of this book to summarize essential up-to-date information for every clinician or scientist interested in how to balance between positive and negative effects of UV-exposure to minimize the risks of developing vitamin D deficiency and skin cancer"--Publisher's description.
  • The SFC market : "yesterday, today, and tomorrow" -- The use of SFC in discovery sciences -- Qualification of SFC hardware and validation of systems -- Method development for achiral SFC -- Achiral preparative supercritical fluid chromatography -- Supercritical fluid chromatography for chiral method development screening and analysis -- Chiral preparative supercritical fluid chromatography -- SFC in process analytical chemistry -- Analytical SFC for impurities -- Supercritical fluid chromatography -- mass spectrometry -- Supercritical fluid chromatography of natural products -- Polarimetric detection in supercritical fluid chromatography -- Supercritical fluid chromatography with ultra-performance particles -- Pilot and production-scale supercritical fluid chromatography.
  • Fundamentals of supercritical fluid technology / Pereda, S., Bottini, S.B. and Brignole, E. -- Supercritical extraction plants / Martinez, J.L. and Vance, S. -- Supercritical fluid extraction of specialty oils / Temelli, F. ... [et al.] -- Extraction and purification of natural tocopherols by supercritical CO / Fang, T. ... [et al.] -- Processing of fish oils by supercritical fluids / Eltringham, W. and Catchpole, O.J. -- Supercritical fluid extraction of active compounds from algae / Mendes, R. -- Application of supercritical fluids in traditional Chinese medicines and natural products / Li, S. -- Extraction of bioactive compounds from Latin American plants / Meireles, M.A. -- Antioxidant extraction by supercritical fluids / Diaz-Reinoso, B. ... [et al.] -- Essential oils extraction and fractionation using supercritical fluids / Reverchon, E. and De Marco, I. -- Processing of spices using supercritical fluids / Mukhopadhyay, M. -- Preparation and processing of micro and nano-scale materials by supercritical fluid technology / Weidner, W. and Petermann, M.
  • MEN1 clinical background / Peter Igaz -- Genetic background of MEN1 : from genetic homogeneity to functional diversity / Patrick Gaudray and Günther Weber -- Menin : the protein behind the MEN1 syndrome / Maria Papaconstantinou ... [et al.] -- Cellular functions of menin / Geoffrey N. Hendy, Hiroshi Kaji and Lucie Canaff -- The role of menin in hematopoiesis / Ivan Maillard and Jay L. Hess -- Role of menin in bone development / Hiroshi Kaji, Lucie Canaff and Geoffrey N. Hendy -- Activin, TGF-€ and menin in pituitary tumorigenesis / Jean-Jacques Lebrun -- The role of menin in parathyroid tumorigenesis / Colin Davenport and Amar Agha -- Role of menin in neuroendocrine tumorigenesis / Terry C. Lairmore and Herbert Chen -- Adrenal tumors in MEN1 syndrome and the role of menin in adrenal tumorigenesis / Attila Patocs, Katalin Balogh and Karoly Racz -- Functional studies of menin through genetic manipulation of the MEN1 homolog in mice / Dheepa Balasubramanian and Peter C. Scacheri.
  • Superoxide distumase 2002
  • PNL is the gold standard for the management of large and/or otherwise complex renal stones. Since its introduction in the seventies PNL has undergone considerable evolution, mainly driven by the improvement in access techniques, endoscopic instrument technology, lithotripsy devices and drainage management. The conventional prone position for PNL has been challenged in the last two decades by a variety of modifications, including the supine and Galdakao-modified supine Valdivia positions, which make simultaneous retrograde working access to the collecting system possible and have proven anesthesiological advantages. The Galdakao-modified supine Valdivia position allowed the development of ECIRS (Endoscopic Combined IntraRenal Surgery), a technique exploiting a combined antegrade and retrograde approach to the upper urinary tract, using both rigid and flexible endoscopes with the related accessories. The synergistic teamwork of ECIRS provides a safe and efficient, minimally-invasive procedure for the treatment of all kinds of urolithiasis. The aim of this book is to share with the urologic community worldwide our experience, our standardization of all the steps, and tips and tricks for the procedure.
  • 1. Febrile neutropenia -- 2. Transfusion support -- 3. Tumor lysis syndrome -- 4. Cardiopulmonary emergencies -- 5. Neurologic emergencies -- 6. Hyperleukocytosis -- 7. The acute abdomen -- 8. Thrombotic disorders -- 9. Pain management -- 10. Nausea and vomiting -- 11. Oral mouth care and mucositis -- 12. Nutrition -- 13. Management of acute radiation side effects -- 14. Prevention of infection -- 15. Hematopoietic growth factors -- 16. Immunization practice in pediatric oncology -- 17. Central venous catheters: care and complications -- 18. Knowledge gaps and opportunities for research.
  • Supportive oncology 2011
    2011 ClinicalKey
  • Natural and induced T CD4+CD25+FOXP3+ regulatory T cells / L. Chatenoud -- Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells / P. Hoffmann, R. Eder and M. Edinger -- Methods for in vitro generation of human type 1 regulatory T cells / S. Gregori, M.G. Roncarolo and R. Bacchetta -- Ex vivo generation of regulatory T cells: Characterization and therapeutic evaluation in a model of chronic colitis / F. Karlsson ... [et al.] -- Phenotypic and functional characterization of CD8(+) T regulatory cells / S. Menoret ... [et al.] -- Regulatory CD4(-)CD8(-) double negative T cells / E.Y. Kim, S.C. Juvet and L. Zhang -- Identifying regulatory B cells (B10 cells) that produce IL-10 in mice / T. Matsushita and T.F. Tedder -- DCs in immune tolerance in steady-state conditions / T. Fukaya ... [et al.] -- Plasmacytoid dendritic cells in tolerance / E. Gehrie ... [et al.] -- In vitro-generated DC with tolerogenic functions: Perspectives for in vivo cellular therapy / C. van Kooten and K.A. Gelderman -- Preparation of mouse bone marrow-derived dendritic cells with immunoregulatory properties / M. Segovia, M.C. Cuturi and M. Hill -- Myeloid-derived suppressor cells: Characterization and expansion in models of endotoxemia and transplantation / N. Van Rompaey and A. Le Moine -- Human regulatory macrophages / J.A. Hutchinson ... [et al.] -- NKT and tolerance / J. Diana ... [et al.] -- Antiinflammatory and immunosuppressive functions of mast cells / J. Kalesnikoff and S.J. Galli -- A mesenchymal stem cell potency assay / J. Jiao ... [et al.] -- In vitro analyses of the immunosuppressive properties of neural stem/progenitor cells using anti-CD3/CD28-activated T cells / V. Bonnamain, I. Neveu and P. Naveilhan -- Immunoregulatory properties of heme oxygenase-1 / P. Blancou ... [et al.] -- Indoleamine 2,3-dioxygenase and regulatory function: Tryptophan starvation and beyond / C. Orabona and U. Grohmann -- Regulatory T cell enrichment by IFN-[gamma] conditioning / G. Feng, K.J. Wood and A. Bushell -- Transforming growth factor-beta: Recent advances on its role in immune tolerance / P.Y. Mantel and C.B. Schmidt-Weber -- Induction of tolerogenic dendritic cells by NF-[kappa]b blockade and fcgamma receptor modulation / L.J. Carreno, C.A. Riedel and A.M. Kalergis -- Fine-tuning antitumor responses through the control of galectin-glycan interactions: An overview / M. Salatino and G.A. Rabinovich -- Regulation of lymphocytes by nitric oxide / C. Bogdan -- Pregnancy: Tolerance and suppression of immune responses / A. Leber ... [et al.] -- Organ transplantation: Modulation of t-cell activation pathways initiated by cell surface receptors to suppress graft rejection / K. Weatherly and M.Y. Braun -- Immunosuppressive mechanisms during viral infectious diseases / G. Sarikonda and M.G. von Herrath -- Ocular immune privilege sites / S. Masli and J.L. Vega -- Immunoprivileged sites: The testis / M. Fijak, S. Bhushan and A. Meinhardt.
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  • Surgery 2009
    Designed to teach you to think like an experienced clinician, this unique resource places as much value on process as it does on content. A case-based organization hones in on the must-know differential diagnoses of the common surgical presentations. Its convenient pocket-sized format enables you to review the material on the go, and online access via Student Consult enhances your study of the material and exponentially boosts your reference power. Provides high-yield core information essential to surgical rotations in a portable, pocket-sized format.Uses a color-coded system that places the core surgical information in a framework of the ACGME Core Competencies.Offers self-assessment activities throughout to promote retention and application of knowledge, including access on line to your own competency-based portfolio tools and competency-specific learning modules (Vertical Reads).Features ACGME Core Competencies enabling you to integrate evidence based medicine, continual self-assessment, and cognizance of interpersonal skills into your daily routine.Includes features such as "Speaking Intelligently" and "Clinical Thinking" in each chapter to help you see the "big picture."Organizes the most common and must-know surgical signs/symptoms and disorders by presentation, making reference simple.Presents "Teaching Visuals"-an interactive teaching device designed to reinforce visual concepts.Equips you to perform a more in-depth review of surgical topics with "Clinical Entities" that are referenced to top surgical references.
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    Abdominal hernias -- Gallstone disease -- Pancreatitis -- Pancreatic tumours -- Benign breast disease -- Breast cancer -- Goitre -- Thyroid malignancies -- Parathyroid disease -- Pituitary disorders -- Adrenal disorders -- Skin cancer -- Ischaemic heart disease -- Valvular heart disease -- Peripheral occlusive vascular disease -- The diabetic foot -- Aneurysms -- Extracranial arterial disease -- Deep venous thrombosis -- Varicose veins -- Lymphoedema -- Pulmonary collapse and postoperative pneumonia -- Bronchial carcinoma -- Urinary tract infection -- Benign prostatic hypertrophy -- Renal calculi -- Renal cell carcinoma -- Carcinoma of the bladder -- Carcinoma of the prostate -- Testicular cancer -- Urinary incontinence -- Paediatric 'general' surgery -- Solid organ transplantation. Neck lump -- Dysphagia -- Haemoptysis -- Breast lump -- Breast pain -- Nipple discharge -- Haematemesis -- Dyspepsia -- Vomiting -- Acute abdominal pain -- Chronic abdominal pain -- Abdominal swellings (general) -- Abdominal swellings (localized) : upper abdominal -- Abdominal swellings (localized) : lower abdominal -- Jaundice -- Rectal bleeding -- Diarrhoea -- Altered bowel habitconstipation -- Groin swellings -- Claudication -- Acute warm painful leg -- Acute 'cold' leg -- Leg ulceration -- Dysuria -- Urinary retention -- Haematuria -- Scrotal swellings -- Stomas and incisions -- Anaesthesia -- Hypoxia -- Shock -- Systemic inflammatory response syndrome (SIRS) -- Surgical infection -- Acute renal failure -- Fractures -- Burns -- Major trauma - basic principles -- Head injury -- Gastro-oesophageal reflux -- Oesophageal carcinoma -- Peptic ulceration -- Gastric carcinoma -- Malabsorption -- Crohn's disease -- Acute appendicitis -- Diverticular disease -- Ulcerative colitis -- Colorectal carcinoma -- Benign anal and perianal disorders -- Intestinal obstruction --
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  • This book provides an educational resource of modern and advanced operative techniques for patients with GI cancers. The textbook is designed to provide a step-by-step surgical approach, highlighting key learning points and potential operative pitfalls. When appropriate, two or more different approaches on an operative procedure are presented to provide additional perspective on surgical techniques. Written descriptions of laparoscopic and robotic cancer operations are paired with online video presentations of the same cancer operation. Written by experts in the field, Surgery for Cancers of the Gastrointestinal Tract: A Step-by-Step Approach provides a concise summary of the current management of each GI cancer and is of great utility to not only surgeons at all levels of training, but also for surgeons in practice who seek to reinforce or learn new surgical techniques.
  • History of auditory implantation -- Surgical anatomy in auditory implantation -- Radiology in auditory implantation -- Instruments and implants -- Cochlear implantation -- Special considerations in pediatric cochlear implantation -- Complications and revision surgery in cochlear implantation -- Auditory brainstem implantation -- Electroacoustic stimulation -- Subtotal petrosectomy in cochlear implantation -- Cochlear implantation in cochlear ossification -- Meningitis and implantation -- Auditory implantation in otosclerosis patients -- Otomastoiditis and cochlear implantation -- Inner ear malformations and implantation -- Neurofibromatosis type 2 and auditory implantation -- Implantation in skull base and temporal bone lesions -- Bone conduction implants -- Active middle ear implants : vibrant soundbridge.
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  • Anatomy and physiology of velopharyngeal closure and insufficiency / Raol, N., Hartnick, C.J -- Nasometry, videofluoroscopy, and the speech pathologist's evaluation and treatment / de Stadler, M., Hersh, C. -- Nasal endoscopy : new tools and technology for accurate assessment / Raol, N. -- New technology : use of cine MRI for velopharyngeal insufficiency / Raol, N., Sagar, P., Nimkin, K., Hartnick, C.J -- Validated patient-reported outcome instruments for velopharyngeal insufficiency / Skriko, J.R., Sie, K.C.Y. -- Prosthodontics rehabilitation in velopharyngeal insufficiency / Jackson, M. -- Superiorly based pharyngeal flap / Raol, N., Hartnick, C.J. -- Sphincter pharyngoplasty / Raol, N., Hartnick, C.J. -- Furlow double-opposing z-plasty / Raol, N., Hartnick, C.J. -- Posterior pharyngeal wall augmentation / Perez, C.F., Brigger, M.T. -- Persistent velopharyngeal insufficiency / Willging, J.P. -- Obstructive sleep apnea / Willging, J.P.
  • Sleep Disordered Breathing / Kerstin Rohde and Thomas Verse -- General Aspects of Therapy / Thomas Verse -- Identifying the Site of Obstruction / Joachim T. Maurer and Thomas Verse -- Nasal Surgery / Thomas Verse and Wolfgang Pirsig -- Nasopharyngeal Surgery / Thomas Verse and Wolfgang Pirsig -- Palatal Surgery / Thomas Verse, Wolfgang Pirsig and Joachim T. Maurer -- Lower Pharyngeal Airway Procedures / Boris A. Stuck, Thomas Verse, Nico de Vries and Joachim T. Maurer -- Maxillofacial Surgeries / Thomas Verse and Thomas Hierl -- Laryngeal OSA / Thomas Verse -- Multilevel Surgery / Thomas Verse -- Tracheotomy / Thomas Verse and Wolfgang Pirsig -- Bariatric Surgery / Helge Kleinhans and Thomas Verse -- Anesthesiologic Airway Management / Harald V. Genzwuerker.
  • Surgery for the dry eye? / Geerling, G., Brewitt, H. -- The normal tear film / Tiffany, J.M. -- Functional anatomy and immunological interactions of ocular surface and adnexa / Paulsen, F. -- Classification and diagnosis of dry eye / Kaercher, T., Bron, A.J. -- Medical management of the dry eye disease / Tuft, S., Lakhani, S. -- Anti-inflammatory and immunosuppressive concepts / Nölle, B. -- Correction of entropion and ectropiona / Hintschich, C. -- Correction of lid retraction and exophthalmos / Baldeschi, L. -- Lacrimal drainage surgery in a patient with dry eyes / Rose, G.E. -- Surgery of the conjunctiva / Yokoi, N., Inatomi, T., Kinoshita, S. -- Surgery of the cornea : corneal, limbal stem cell, and amniotic membrane transplantation / Kruse, F.E., Cursiefe, C. -- Keratoprosthesis surgery / Liu, C. ... [et al.] -- Eyelid botulinum toxin injections for the dry eye / Sahlin, S., Linderoth, R. -- Plugs for occlusion of the lacrimal drainage system / Tost, F.H.W., Geerling, G. -- Surgical occlusion of the lacrimal drainage system / Geerling, G., Tost, F.H.W. -- Mucous membrane grafting / Henderson, H.W.A., Collin, J.R.O. -- Minor salivary gland transplantation / Geerling, G., Raus, P., Murube, J. Transplantation of the major salivary glands / Geerling, G., Sieg, P. -- Mechanical pump dacryoreservoirs / Murube, J., Geerling, G. -- Clinical trials in dry eye in surgery for dry eye? / Lemp, M.A. -- Animal models of dry eye / Schrader, S., Mircheff, A.K., Geerling, G. -- Flow chart on surgical approaches to dry eye / Geerling, G., Brewitt, H.
  • Filling a significant knowledge gap, this book brings the latest information to the evaluation and treatment of patients with a dysfunctional sacroiliac (SI) joint. Beginning with an overview of current anatomical knowledge and the role of pain and surgery, diagnosis and treatment approaches are carefully presented as individual chapters - featuring the origin of each surgical approach, the approach itself, its literary foundation, and overall available results. The final emphasis of the book is on post-operative concerns - including complications, bracing options, rehabilitation and managing patient expectations. Spine surgeons, physical therapists, and other professionals who treat the SI joint will find Surgery for the Painful, Dysfunctional Sacroiliac Joint to be an invaluable resource.
  • Etiology and epidemiology of urinary incontinence / W. Stuart Reynolds -- Preoperative evaluation of patients with urinary incontinence and selection of appropriate surgical procedures for stress incontinence / W. Stuart Reynolds Mickey Karram -- Surgical anatomy of the anterior vaginal wall, retropubic space, and inner groin / Mickey Karram -- Retropubic operations for stress urinary incontinence / Mark D. Walters -- Biologic bladder neck pubovaginal slings / Mickey Karram, Dani Zoorob, and W. Stuart Reynolds -- Retropubic synthetic midurethral slings / Mickey Karram, Dani Zoorob, and W. Stuart Reynolds -- Transobturator synthetic midurethral slings / Dani Zoorob and Mickey Karram -- Single incision minislings / Mickey Karram, W. Stuart Reynolds, and Dani Zoorob -- Surgical management of voiding dysfunction and retention after stress incontinence surgery / Mickey Karram -- Bulk enhancing agents for stress incontinence : indications and techniques / Roger Dmochowski -- Sacral neuromodulation / W. Stuart Reynolds and Roger Dmochowski -- Botulinum toxin injection therapy / W. Stuart Reynolds and Roger Dmochowski -- Bladder augmentation / W. Stuart Reynolds and Roger Dmochowski -- Mixed and recurrent incontinence, incontinence in patients with pelvic organ prolapse, and how best to avoid and manage complications; case discussions / Mickey Karram, W. Stuart Reynolds, and Roger Dmochowski.
  • Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.
  • History of cerebellopontine angle surgery -- Microsurgical anatomy of the cerebellopontine angle by the retrosigmoid approach -- Neuropathology of the cerebellopontine angle and its surroundings -- Approaches to the cerebellopontine angle -- Vestibular schwannomas -- Neurofibromatosis Type 2 and other bilateral cerebellopontine angle tumors -- Meningiomas -- Cerebellopontine angle epidermoids -- Nonvestibular schwannomas -- Jugular foramen tumors -- Other cerebellopontine angle tumors -- Management of facial palsy.
  • Section I: Brachial plexus injury and entrapments -- Brachial plexus avulsion--diagnostic issues / Thomas Kretschmer and Robert L. Tiel -- Upper brachial plexus injury (duchenne-erb palsy) / Andrew C. Kam and Daniel H. Kim -- Lower trunk brachial plexus palsy / Lynda J-S. Yang and John E. McGillicuddy -- Gunshot wounds to the brachial plexus / Robert J. Spinner and Robert L. Tiel -- Lateral cord injury / Robert L. Tiel and Eric L. Zager -- Medial cord injury / Robert J. Spinner and Robert L. Tiel -- Pediatric plexus injuries / James M. Drake, Patrick A. Lo, and Rajiv Midha -- Secondary reconstruction in obstetric brachial plexus injuries / Rahul K. Nath ... [et al.] -- Free functioning muscle transfers for upper extremity reconstruction of plexus palsy / Dimitri J. Anastakis and Ralph T. Manktelow -- Dorsal root entry zone: lesioning for intractable deafferentation pain / Mahmood Fazl ... [et al.] -- Neurotization in brachial plexus injury / Rahul K. Nath ... [et al.] -- Thoracic outlet syndrome / Eric L. Zager -- Nerve transfers for shoulder reanimation / Bassam M. J. Addas and Rajiv Midha -- Fascicular nerve transfers to restore elbow flexion / Ronald T. Grondin, S. Durand, and Christophe Oberlin -- Section II: Upper extremity peripheral nerve injuries and entrapments -- Spinal accessory nerve palsy / Robert L. Tiel and Eric L. Zager -- Long thoracic nerve palsy / Adrian W. Laxton and Rajiv Midha -- Suprascapular nerve palsy / Adrian W. Laxton and Rajiv Midha -- Axillary nerve injury and repair / Deb Bhowmick and Eric L. Zager -- Injury to the median nerve above the elbow / Ben Roitberg -- Anterior interosseous nerve syndrome/compression / Allen H. Maniker -- Carpal tunnel syndrome / Sheila K. Singh and Rajiv Midha -- Endoscopic carpal tunnel release / David F. Jimenez and Thomas Loftus -- Recurrent or persistent symptoms following carpal tunnel release / Brent Graham -- Digital nerve injuries / Paul Binhammer -- Ulnar nerve injury / Marie-Noëlle Hébert-Blouin and Line Jacques -- Failed ulnar nerve transposition due to unrecognized snapping of the medial triceps / Robert J. Spinner and Rajiv Midha -- Ulnar nerve entrapment at the elbow / Farhad Pirouzmand and Rajiv Midha -- Ulnar nerve compression--guyon canal / Christopher Doumas and David R. Steinberg -- Failed ulnar nerve decompression / James B. Lowe III and Susan E. Mackinnon -- Management of penetrating (lacerating) nerve injuries / Mandeep S. Tamber and Rajiv Midha -- Radial nerve injury: midhumeral level / Mubarak Al-Gahtany and Rajiv Midha -- Radial tunnel syndrome / Farhad Pirouzmand and Rajiv Midha -- Posterior interosseous nerve injury / Andrew Nataraj and Rajiv Midha -- Nerve repair with conduits / Matthew Sanborn, Eric M. Jackson, and Eric L. Zager -- Section III: Lower extremity peripheral nerve injuries and entrapments -- Ilioinguinal/iliohypogastric neuropathy / R. Graham Vanderlinden and Rajiv Midha -- Meralgia paresthetica / Douglas Cook and Rajiv Midha -- Obturator nerve injury and repair / Jason H. Huang, Robert G. Whitmore, and Eric L. Zager -- Femoral neuropathy by compression from iliacus compartment hematoma / Farhad Pirouzmand and Rajiv Midha -- Femoral nerve injuries / Allen H. Maniker -- Saphenous nerve lesions / Robert J. Spinner and Robert L. Tiel -- Sciatic nerve compression and piriformis syndrome / Robert J. Spinner and Robert L. Tiel -- Sciatic nerve injury and repair / Robert G. Whitmore, Deb Bhowmick, and Eric L. Zager -- Diagnosis and treatment of common peroneal nerve problems / Tarvinder Singh and Michel Kliot -- Peroneal nerve entrapment / Kimberly Harbaugh and Rajiv Midha -- Sural nerve injury and neuroma / Rajiv Midha -- Posterior tibial nerve injury / Justin L. Owen ... [et al.] -- Tarsal tunnel syndrome / Robert J. Spinner and Robert L. Tiel -- Morton neuroma / Neal J. Naff -- Section IV: Nerve tumors, painful nerve conditions, and miscellaneous injuries -- Schwannoma / W. Bradley Jacobs and Rajiv Midha -- Neurofibroma / W. Bradley Jacobs and Rajiv Midha -- Management of malignant peripheral nerve sheath tumors / Nabeel Al-Shafai, Rajiv Midha, and Abhijit Guha -- Brachial plexus tumor / Mubarak Al-Gahtany and Rajiv Midha -- Neurogenic sarcoma of the sciatic nerve / Charles Christian Matouk and Rajiv Miidha -- Lumbar plexus injury / Eric M. Jackson and Eric L. Zager -- Complex regional pain syndrome / Raqeeb Haque and Christopher J. Winfree -- Upper dorsal sympathectomy for hyperhidrosis / Mahmood Fazl -- Electrical stimulation for painful neuroma / Michael J. Dorsi and Allan J. Belzberg.
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  • This book addresses shoulder instability--all comers because the extreme variability of patients and pathology must be matched with a variety of techniques.
  • History -- Anatomy -- Intramedullary tumors -- Extramedullary tumors -- Epidural tumors.
  • Historical Background or De quibusdam Renum glandulis: The History of Adrenals / Donatella Lippi -- Surgical Anatomy / Celestino Pio Lombardi, Carmela De Crea, Francesco Pennestri and Marco Raffaelli -- Pathology / Gabriella Nesi and Raffaella Santi -- Diagnosis and Clinical Pictures / Gabriele Parenti and Massimo Mannelli -- Imaging / Massimo Falchini and Vittoria Rufini -- Perioperative Management / Tommaso Borracci, Luca Vitali, Lorenzo Antonuzzo, Liliana Sollazzi and Valter Perilli, et al. -- General Principles of Adrenal Surgery / Robin M. Cisco and Quan-Yang Duh -- Instrumentation and High-Technology / Francesco Corcione, Valentina Brancato and Michele Giuseppe Iovino -- Right Flank Trans-Abdominal Laparoscopic Adrenalectomy / Carlo Bergamini and Andrea Valeri -- Left Flank Trans-Abdominal Laparoscopic Adrenalectomy / Celestino Pio Lombardi, Marco Raffaelli, Carmela De Crea, Francesco Pennestri and Rocco Bellantone -- Posterior Retroperitoneoscopic Adrenalectomy / Rocco Bellantone, Marco Raffaelli, Carmela De Crea, Luigi Oragano and Celestino Pio Lombardi -- Open Adrenalectomy / Giorgio De Toma, Andrea Polistena and Giuseppe Cavallaro -- Other Techniques of Video-Assisted and Open Adrenalectomies / Rocco Bellantone, Francesco Corcione, Celestino Pio Lombardi, Marco Raffaelli and Carmela De Crea, et al. -- Outcome of Adrenal Surgery / Andrea Valeri and Carlo Bergamini.
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    v.1. The Esophagus -- v. 2. Stomach and duodenum, incisions, sutures -- v. 3. Colon, anorectal tract -- v. 4. Pancreas, biliary tract, liver, spleen -- v. 5. Mesentery vasculature; hernias; small intestine; peritoneum, omentum, mesentery and retroperitoneum; surgical nutrition.
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    v. 1. General consideratons and intracapsular cataract extraction / by J. Barraquer, J. Rutllán ; with the cooperation of R.C. Troutman -- v. 2. Surgery of the cornea.
  • This book gives comprehensive coverage of common and rare colorectal conditions, advances in the molecular biology and genetics of colorectal diseases, new laparoscopic techniques, and more. Contributions from international experts on specialized topics and 400 new illustrations ensure that the extensive text is not only current and authoritative, but easy to understand.
  • Section I. Foundations for Surgical Treatment -- Section II. Surgical Indications and Decision Making -- Section III. Surgical Techniques -- Section IV Fixation and Fusion Techniques.
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  • Surgery of the hip 2013
    Surgery of the Hip is your definitive, comprehensive reference for hip surgery, offering coverage of state-of-the-art procedures for both adults and children. Modelled after Insall & Scott Surgery of the Knee, it presents detailed guidance on the latest approaches and techniques, so you can offer your patients - both young and old - the best possible outcomes.
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  • Surgery of the knee 2014
    The knee presents numerous challenges to the orthopaedic surgeon and this book presents techniques and guidance both for common surgical procedures and also for rare and difficult interventions in knee surgery. Surgical techniques and approaches in knee surgery are covered as well as postoperative complications and rehabilitation. Chapters also discuss clinical examination and preparation of the patient prior to the procedure. Surgery of the Knee is a comprehensive step-by-step guide that features more than 500 operative photographs, radiological and surgical drawings of exceptional quality. The Editors have brought together a team of experts within the field ensuring that orthopaedic surgeons in training and those wishing to improve their knowledge of the knee will find this book to be an indispensable resource for performing knee surgery.
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    Surgical and radiologic anatomy of the liver, biliary tract, and pancreas -- Assessment of liver function in the surgical patient -- Liver blood flow: physiology, measurement, and clinical relevance -- Liver regeneration -- Liver hyperplasia, hypertrophy, and atrophy -- Bile secretion -- Biliary tract pathophysiology -- Pancreatic physiology and functional assessment -- Endotoxin and cytokines in liver and biliary tract disease -- Infections in hepatic, biliary, and pancreatic surgery -- Genetics and molecular biology of pancreatic and biliary cancers -- Molecular biology of liver carcinogenesis and hepatitis -- Liver immunology -- Clinical investigation of hepatopancreatobiliary disease -- Ultrasound of the liver, biliary tract, and pancreas -- Endoscopic ultrasound -- The role of nuclear medicine in the diagnosis and management of hepatobiliary and pancreatic diseases -- Computed tomography of the liver, biliary tract, and pancreas -- Magnetic resonance imaging of the liver, biliary tract, and pancreas -- Direct cholangiography -- Angiography -- Percutaneous biopsy -- Intraoperative diagnosis of liver, biliary, and pancreatic disease -- Preoperative and postoperative nutrition in hepatobiliary surgery -- Anesthesia and postoperative intensive care -- Perioperative critical care in hepatobiliary surgery -- Quality of life and hepatobiliary tumors -- Interventional endoscopy: technical aspects -- Radiologic hepatobiliary interventions -- Biliary-enteric anastomosis -- The natural history of gallstones and asymptomatic gallstones -- Cholecystitis -- Percutaneous approaches to the treatment of gallbladder disease -- The technique of cholecystectomy -- Laparoscopic cholecystectomy and choledocholithotomy -- Stones in the common bile duct-clinical features and open surgical approaches and techniques -- Stones in the bile duct: endoscopic and percutaneous approaches -- Cholecystolithiasis and stones in the common bile duct: which approach, when? -- Postcholecystectomy problems -- Intrahepatic stones -- Biliary atresia -- Primary sclerosing cholangitis -- Biliary stricture and fistula -- Definition and classification of pancreatitis -- Etiology, pathogenesis, and diagnostic assessment of acute pancreatitis -- Management of acute pancreatitis and complications -- Etiology, pathogenesis, and diagnosis of chronic pancreatitis -- Management of chronic pancreatitis: conservative, endoscopic, and surgical -- Tumors of the bile ducts-pathologic aspects -- Benign tumors and pseudotumors of the biliary tract -- Tumors of the gallbladder -- Intrahepatic and extrahepatic biliary cancer -- Pathology and classification of pancreatic and ampullary tumors -- Periampullary and pancreatic tumors -- Palliation of pancreatic and periampullary tumors -- Pancreaticoduodenectomy, distal pancreatectomy, segmental pancreatectomy, total pancreatectomy, and transduodenal resection of the papilla of vater -- Endocrine tumors of the pancreas: clinical picture, diagnosis, and therapy -- Cholangitis -- Pyogenic liver abscess -- Amebiasis and other parasitic infections -- Hydatid cyst of the liver -- Recurrent pyogenic cholangitis -- Bile duct cysts in adults -- Nonparasitic cystic diseases of the liver and intrahepatic biliary tree -- Surgical management of cystic disease of the liver -- Liver, biliary, and pancreatic injury -- Aneurysm and arteriovenous fistula of the liver and pancreatic vasculature -- Hemobilia and bilhemia -- Tumors of the liver-pathologic aspects -- Benign liver lesions -- Hepatocellular carcinoma -- Hepatic tumors in childhood -- Metastatic tumors -- Embolization of liver tumors -- Radiotherapy of liver tumors -- Ablation of liver tumors -- Chemotherapy of liver tumors -- Isolated hepatic perfusion for extensive liver cancers -- Intra-arterial chemotherapy for liver tumors -- Liver resection for benign disease and for liver and biliary tumors -- Vascular isolation techniques in liver resection -- Liver resection in cirrhosis of the liver -- Segment-oriented anatomic liver resections -- Portal vein embolization -- Ex vivo and in situ hypothermic hepatic resection -- Intraoperative ultrasound of the liver: techniques for liver resection and transplantation -- Cirrhosis and portal hypertension: pathologic aspects -- Management of liver failure -- Support of the failing liver -- Management of ascites in cirrhosis and portal hypertension -- Medical management of bleeding varices -- Endoscopic therapy in the management of esophageal varices: injection sclerotherapy and variceal ligation -- Portal hypertension in children -- Operative devascularization and esophageal transection -- The place of portosystemic shunting -- The place of transjugular intrahepatic portosystemic shunting -- The technique of portacaval shunt -- Distal splenorenal shunt -- The mesocaval shunt: technique -- Budd-chiari syndrome and veno-occlusive disease -- Liver and pancreatic transplantation immunobiology -- Liver transplantation: anesthesia, perioperative management, and postoperative intensive care -- Liver transplantation: indications -- Orthotopic liver transplantation -- Liver transplantation in patients with fulminant hepatitis -- Liver transplantation for tumors -- Liver transplantation in children and segmental transplantation -- Auxiliary liver transplantation -- Living donor liver transplantation -- Early and late complications of liver transplantation -- Techniques of liver replacement -- Whole organ pancreas and pancreatic islet transplantation.
  • Surgery of the pediatric spine 2008
    Thieme eNeurosurgery
    This book is a comprehensive multidisciplinary reference for the surgical management of the most frequently encountered spine problems in the pediatric patient. An overview of developmental and clinical aspects provides essential information on biomechanics, neuroimaging, preoperative evaluation, anesthesia, and neurophysiological monitoring. The book goes on to present the surgical anatomy and various approaches to the spine and spinal cord. Chapters are grouped into easy-to-reference sections that are organized by type of problem, including congenital anomalies and developmental disorders; neoplasms; vascular malformations; inflammatory and infectious diseases; neuromuscular disease; trauma; and deformities. The book also presents special techniques for the treatment of spinal deformity, such as osteotomy, vertebrectomy, VEPTR expansion thoracoplasty, and fusionless techniques. A chapter devoted to the rehabilitation of children with spinal cord injury covers the principles and key concepts in treatment, as well as the possible secondary complications and challenges that are unique to pediatric patients.
  • Anatomy for procedural dermatology / June K. Robinson -- Aseptic technique / Christie R. Travelute and Todd V. Cartee -- Anesthesia and analgesia / Teresa T. Soriano, Andrew Breithaupt, and Cameron Chesnut -- Instruments and materials / William Lear -- Patient evaluation, informed consent, preoperative assessment, and care / Mara C. Weinstein and Allison T. Vidimos -- Antibiotics / Kavita Mariwalla -- Wound healing / Sonia Lamel, Jie Li, and Robert S. Kirsner -- Wound healing and its impact on dressings and posoperative care / Yakir Levin, Katherine L. Brown, and Tania J. Phillips -- Electrosurgery / Diana Bolotin and Murad Alam -- Cryosurgery / Paola Pasquali -- Skin biopsy techniques / Andrew G. Affleck and Graham Colver -- Incision, draining, and exteriorization techniques / Masato Yasuta -- Suturing technique and other closure materials / Divya Srivastava and R. Stan Taylor -- Complex layered facial closures / Edgar F. Fincher, Hayes B. Gladstone, and Ronald L. Moy -- Hemostasis / Pedro Redondo -- Ellipse, ellipse variations, and dog-ear repairs / Allison Hanlon, Samuel E. Book, and David J. Leffell -- Random pattern cutaneous flaps / Jonathan L. Cook, Glenn D. Goldman, and Todd E. Holmes -- Axial pattern flaps / Christopher J. Miller, Tri Nguyen, and Joseph F. Sobanko -- Skin grafting / Alvaro E. Acosta ... [and 4 others] -- Acne scar revision / Greg J. Goodman -- Revision of surgical scars / Justin J. Leitenberger ... [and 3 others] -- Psychosocial issues and the cosmetic surgery patient / Dee Anna Glaser -- Evaluation and management of the aging face / Lisa M. Donofrio -- Soft-tissue augmentation / C. William Hanke ... [and 4 others] -- Chemical peels / Marina Landau and Sahar F. Ghannam -- Implants / J. Michael Carney -- Botulinum toxins / Doris Hexsel and Camile L. Hexsel -- Liposuction / C. William Hanke ... [and 4 others] -- Autologous fat transfer : evolving concepts and techniques / Kimberly J. Butterwick -- Follicular unit hair transplantation / Robert M. Bernstein -- Laser hair removal / William G. Stebbins ... [and 3 others] -- Laser treatment of tattoos and pigmented lesions / Rachel N. Pritzker ... [and 3 others] -- Photodynamic therapy / Anne Goldsberry ... [and 3 others] -- Laser-based treatment of the aging face for skin resurfacing : ablative and non-ablative lasers / Omar A. Ibrahimi, Nazanin Saedi, and Suzanne L. Kilmer -- Laser and light treatment of acquired and congenital vascular lesions / Johnny Chun Yin Chan and Henry Hin Lee Chan -- Sclerotherapy of varicose veins / Eberhard Rabe, Franz X. Breu, and Felizitas Pannier -- Endovenous thermal ablation techniques with ambulatory phlebectomy for varicose veins / Sanja Schuller-Petrović, Felizitas Pannier, and Milos̆ D. Pavlović -- Lamellar high-SMAS minimum incision face lift / Robert C. Langdon -- Vertical vector face lift with local anesthesia / Rafael A. Schulze, Brian Somoano, and Greg S. Morganroth -- Blepharoplasty and brow-lift / Alina Fratila and young Kyoon Kim -- Rejuvenation of the neck using liposuction and other techniques / William G. Stebbins, Michael S. Kaminer, and C. William Hanke -- Rejuvenation of the external female genitalia / Doris Hexsel, Sebastian Pop, and Antonio Rusciani -- Keloid management / Brian Berman, Sadegh Amini, and Hilary Baldwin -- Vitiligo surgery / Niti Khunger, Koushik Lahiri, and Venkataram Mysore -- Mohs micrographic surgery and cutaneous oncology / Hubert T. Greenway ... [and 4 others] -- Leg ulcer management / Ysabel Bello... [and 3 others] -- Nail surgery / Eckart Haneke -- Repair of the split earlobe, ear piercing, and earlobe reduction / Sirunya Silapunt and Leonard H. Goldberg -- Hidradenitis suppurativa / Virginia J. Reeder, David Ozog, and Iltefat Hamzavi -- Assessment and treatment of photoaging-related mottled pigmentation / Se Young Na and Kyoung Chan Park -- Design of the surgical suite, including large equipment, and monitoring devices / Ross M. Levy and C. William Hanke -- Dermatology office accreditation / Ross M. Levy. Emily Tierney, and C. William Hanke.
  • Comprehensive surgical textbook on the diagnosis and management of benign and malignant disease of the thyroid and parathyroid glands.
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  • Surgery on the move 2014
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    Pre and postoperative care -- Critical care : anesthesiology, blood gases, and respiratory care -- Skin : wounds, infections, and burns : hands : plastic surgery -- Trauma and shock -- Transplants, immunology, and oncology -- Endocrine problems and the breast -- Gastrointestinal tract, liver, and pancreas -- Cardiothoracic problems -- Peripheral vascular problems -- Urology -- Orthopedics -- Neurosurgery -- Otolaryngology -- Pediatric surgery.
  • Surgery review illustrated 2005
    AccessSurgery, Users must register and sign in to take a test
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  • "The Fifth Edition of Greenfield's Surgery has been thoroughly revised, updated, and refocused to conform to changes in surgical education and practice. Reflecting the increasingly clinical emphasis of residency programs, this edition features expanded coverage of clinical material and increased use of clinical algorithms. Key Points open each chapter, and icons in the text indicate where Key Points are fully discussed. Many of the black-and-white images from the previous edition have been replaced by full-color images"--Provided by publisher.
  • Surgery: A Case Based Clinical Review provides the reader with a comprehensive understanding of surgical diseases in one easy-to-use reference that combines multiple teaching formats. The book begins using a case based approach. The cases presented cover the diseases most commonly encountered on a surgical rotation. The cases are followed by a series of short questions and answers, designed to provide further understanding of the important aspects of the history, physical examination, differential diagnosis, diagnostic work-up and management, and questions that may arise on surgical rounds. Key figures and tables visually reinforce the important elements of the disease process. Surgery: A Case Based Clinical Review will be of great utility for medical students when they rotate on surgery, interns, physician assistant students, nursing students, and nurse practitioner students.
  • Surgery: An Introductory Guide is an all-in-one reference that provides the vital information needed to get the best learning experience out of an operation, and presents it in a convenient, efficient, and portable format. Each section brings together the key points from several different fields including anatomy, pathophysiology, radiology, surgical technique, and clinical guidelines. The operations covered represent the breadth of general surgery including hernia repair, cholecystectomy, breast surgery, general bowel surgery, and vascular surgery. Each chapter provides informative text, bulleted lists, and common OR questions, combined with classic radiology images, diagrams, and a color illustration of the operative anatomy. This method of using key words, high-yield diagrams, and illustrations enhances the ability to quickly absorb and retain the relevant information. The volume is also organized by operation rather than by pathological topic, which lends itself to quick review before each case. Written by Dr. Sarpel, a surgeon and former co-clerkship director who has been honored with multiple teaching awards, Surgery: An Introductory Guide is of great value to medical students and junior residents rotating on general surgery.
  • Surgery-- PreTest self-assessment and review. 13th ed. 2012
    AccessSurgery, Users must register and sign in to take a test
    Pre- and postoperative care -- Critical care : anesthesiology, blood gases, and respiratory care -- Skin : wounds, infections, and burns : hands : plastic surgery -- Trauma and shock -- Transplants, immunology, and oncology -- Endocrine problems and the breast -- Gastrointestinal tract, liver, and pancreas -- Cardiothoracic problems -- Peripheral vascular problems -- Urology -- Orthopedics -- Neurosurgery -- Otolaryngology -- Pediatric surgery.
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  • Featuring an expanded focus on in-demand endoscopic and minimally invasive spine procedures, Surgical Anatomy and Techniques to the Spine, 2nd Edition pairs new anatomic photographs and radiographic images with expertly rendered color illustrations and clear, step-by-step descriptions to help you effectively perform all of the latest and most effective spine surgery techniques. A multidisciplinary approach makes this medical reference book relevant and informative to all surgeons regardless of their specialty or level of surgical experience with the spine. Proceed with confidence. An atlas-style format featuring clear, concise, step-by-step descriptions of the anatomy and procedures along with clinical hints and pearls, tables, and management algorithms provideing swift answers and trusted guidance.Sharpen your surgical acumen with a deeper understanding of the anatomy of the surgical target and related anatomy. Comprehensive information on cervical, cervical/thoracic, thoracic/lumbar, lumbar spine, lumbar/pelvis, and other surgical locations ensures the best approaches to spine surgery and results.Understand the spine from all angles with multiple-viewpoint, full-color photographs, and illustrations.
  • Generations of residents and general surgeons have relied upon and worn out their copies of Surgical Anatomy and Technique: A Pocket Manual. Thoroughly revised and with dozens of new illustrations, the fourth edition continues the tradition of providing a concise, accessible, and generously illustrated memory refresher for both novice and experienced clinicians. The editors have included techniques to keep the content fresh, relevant, and practice-based. Among the new topics are hand surgery, a section on central venous access, and creating an AV fistula for dialysis. All the existing chapters have been updated and expanded to reflect current surgical approaches and instrumentation. This fourth edition of Surgical Anatomy and Technique: A Pocket Manual provides the gold standard in correlating clear, practical anatomy with the correct technique in the pursuit of the best possible patient outcomes. This handy pocket manual remains a "must have" for every resident and general surgeon.
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  • This atlas provides all the basic and advanced information required by surgeons in order to understand fully the skull base anatomy. It is organized according to anatomo-surgical pathways to the hidden areas of the skull base. These pathways are described in step-by-step fashion with the aid of a wealth of color images and illustrations. The emphasis is on endoscopic anatomy, but in order to provide a holistic perspective, informative three-dimensional reconstructions are presented alongside the endoscopic images and radiologic images are included when appropriate. In effect, windows are opened
  • Physics : include medical precautions -- Instrumentation -- Advanced technologies : 3D ultrasound, contrast ultrasound -- Ultrasound of the neck, thyroid and parathyroid -- Breast ultrasound -- Abdominal ultrasound : principles (transabdominal, intraoperative, laparoscopic) -- Hepatobiliary ultrasound : include rf and other ablative therapies -- Ultrasound of pancreas -- FAST : trauma ultrasound -- Critical care ultrasound : includes chest ultrasound -- Endoscopic ultrasound : foregut including esophagus, stomach, small intestine, biliary -- Endoscopic ultrasound : hindgut including endorectal -- Genitourinary ultrasound -- Vascular ultrasound -- Ultrasound-guided regional anesthesia -- Therapeutic ultrasound -- Documentation, coding, billing, and compliance -- Credentialing.
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  • Cardiac Anatomy: Nomenclature and Abbreviations -- Position and Observation of the Heart and Surgical Approaches -- The Right Atrium -- The Right Ventricle -- The Coronary Artery -- The Conduction System of the Heart -- The Left Atrium -- The Left Ventricle -- The Cardiac Skeleton and the Aortic Root -- General Considerations of Cardiac Embryology -- Atrial Septal Defect and Cor Triatriatum -- Atrioventricular Septal Defect -- Ventricular Septal Defect -- Anomalous Pulmonary Venous Drainage -- Aortic Arch Coarctation and Interrupted Aortic Arch -- Congenital Anomalies of the Tricuspid Valve -- Right Ventricular Outflow Tract Obstruction -- Mitral Atresia and Hypoplastic Left Ventricle -- Single Ventricle -- Persistent Truncus Arteriosus -- Aortopulmonary Window -- Aneurism of the Sinus of Valsalva -- Tetralogy of Fallot -- Double Outlet Right Ventricle -- Complete Transposition of the Great Arteries -- Corrected Transposition of the Great Arteries -- Pulmonary Atresia -- Double-outlet of Left Ventricle.
  • A brief history of perforator flaps -- Anatomy, classification and nomenclature -- Intra-operative techniques in perforator dissection -- Pedicled perforator flaps -- Combined perforator flaps -- Thinned perforator flaps -- Flow-through perforator flaps -- Lateral Arm Perforator Flap -- Medial arm perforator flap -- Radial Artery Perforator Flap -- Ulnar Artery Perforator Flap -- posterior interosseous artery perforator flap -- Posterolateral mid-forearm perforator flap -- Dorsal Metacarpal Artery Perforator Flaps -- Dorso-ulnar metacarpal perforator flap of the little finger -- Digital artery perforator flap -- Perforator flaps in the lateral thoracic region -- Deep inferior epigastric artery perforator (DIEP) flap -- Anterolateral thigh perforator flap -- Vastus medialis perforator flap -- Saphenous artery perforator flap -- Posterior thigh perforator flap -- Anterior tibial artery perforator flap -- Posterior tibial artery perforator flap -- Peroneal artery perforator flap -- Medial sural artery perforator flap -- Peroneal artery anterolateral supramalleolar flap -- Anterior supramalleolar perforator flap -- Medial supramalleolar perforator flap -- Dorsal metatarsal artery perforator flap.
  • This atlas depicts and describes the newest arthroscopic and open techniques for dealing with sports orthopaedic injuries and problems. More than 75 surgical procedures are presented step by step with the aid of superb illustrations. Arthroscopic views, artist drawings, X-rays, and clinical and operative photographs are all included to demonstrate exactly how each procedure should be performed. Individual sections are devoted to the shoulder, elbow, pelvis/hip, knee, and ankle/foot. By offering complete illustrated guidance on the surgical management of sports-related injuries, the Surgical Atlas of Sports Orthopaedics and Sports Traumatology will prove invaluable to both novice and experienced surgeons.
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  • Front Matter -- Supplemental Images -- Surgical Critical Care. Respiratory and Cardiovascular Physiology / Marcin A Jankowski, Frederick Giberson -- Cardiopulmonary Resuscitation, Oxygen Delivery, and Shock / Timothy J Harrison, Mark Cipolle -- Arrhythmias, Acute Coronary Syndromes, and Hypertensive Emergencies / Harrison T Pitcher, Timothy J Harrison -- Sepsis and the Inflammatory Response to Injury / Juan C Duchesne, Marquinn D Duke -- Hemodynamic and Respiratory Monitoring / Christopher S Nelson, Jeffrey P Coughenour, Stephen L Barnes -- Airway Management, Anesthesia, and Perioperative Management / Jeffrey P Coughenour, Stephen L Barnes -- Acute Respiratory Failure and Mechanical Ventilation / Lewis J Kaplan, Adrian A Maung -- Infectious Disease / Charles Kung Chao Hu, Heather Dolman, Patrick McGann -- Pharmacology and Antibiotics / Michelle Strong -- Transfusion, Hemostasis and Coagulation / Stacy Shackelford, Kenji Inaba -- Analgesia and Sedation / Juan C Duchesne, Marquinn D Duke -- Delirium, Alcohol Withdrawal, and Psychiatric Disorders / Meghan Edwards, Ali Salim -- Acid-Base, Fluid and Electrolytes / Charles Kung Chao Hu, Andre Nguyen, Nicholas Thiessen -- Metabolic Illness and Endocrinopathies / Therese M Duane, Andrew Young -- Hypothermia and Hyperthermia / Raquel M Forsythe -- Acute Kidney Injury / Terence O'keeffe -- Liver Failure / Bellal Joseph -- Nutrition / Rifat Latifi -- Neurocritical Care / Scott H Norwood, Herb A Phelan -- Venous Thromboembolism / Herb A Phelan, Scott H Norwood -- Transplantation, Immunology, and Cell Biology / Leslie Kobayashi -- Obstetric Critical Care / Gerard J Fulda, Anthony Sciscione -- Envenomations, Poisonings and Toxicology / Michelle Strong -- Common Procedures in the ICU / Adam D Fox, Daniel N Holena -- Diagnostic Imaging, Ultrasound, and Interventional Radiology / Randall S Friese, Terence O'Keeffe -- Emergency Surgery. Neurotrauma / Bellal Joseph -- Blunt and Penetrating Neck Trauma / Leslie Kobayashi -- Cardiothoracic and Thoracic Vascular Injury / Leslie Kobayashi -- Abdominal and Abdominal Vascular Injury / Leslie Kobayashi -- Orthopedic and Hand Trauma / Brett D Crist, Gregory J Della Rocca -- Peripheral Vascular Trauma / Daniel N Holena, Adam D Fox -- Urologic Trauma / Hoylan Fernandez, Scott Petersen -- Care of the Pregnant Trauma Patient / Julie L Wynne, Terence O'Keeffe -- Esophagus, Stomach, and Duodenum / Andrew Tang -- Small Intestine, Appendix, and Colorectal / Jay J Doucet, Vishal Bansal -- Gallbladder and Pancreas / Andrew Tang -- Liver and Spleen / Narong Kulvatunyou -- Incarcerated Hernias / Narong Kulvatunyou -- Soft-Tissue and Necrotizing Infection / Joseph J DuBose -- Obesity and Bariatric Surgery / Stacy A Brethauer, Carlos V R Brown -- Burns, Inhalation Injury, Electrical and Lightning Injuries / Joseph J DuBose -- Urologic and Gynecologic Surgery / Julie L Wynne -- Cardiovascular and Thoracic Surgery / Jared L Antevil, Carlos V R Brown -- Extremes of Age: Pediatric Surgery and Geriatrics / Michael C Madigan, Gary T Marshall -- Telemedicine and Surgical Technology / Rifat Latifi -- Statistics / Randall S Friese -- Ethics, End-of-Life, and Organ Retrieval / Lewis J Kaplan, Felix Lui -- Index.
  • With the introduction of new post-graduate Medical training in the UK, virtually all doctors will be exposed to some form of surgical training prior to specialization. Many of these doctors will have little exposure to surgical emergencies in medical school. Thus, they may unnecessarily refer to a senior doctor when not needed, or catastrophically neglect a patient needing urgent surgical opinion. Surgical Emergencies in Clinical Practice is a compact resource which allows any clinician, without previous surgical knowledge, to be able to make an accurate diagnosis and have a treatment plan for the whole spectrum of surgical emergencies. The essential steps of initial management of all surgical emergencies is outlined in a manner that can be used on a day-to-day basis for clinical management. Written by experts in the field, Surgical Emergencies in Clinical Practice is a valuable tool for all junior doctors and medical students in the UK, Europe, Asia and North America. It will also be of interest to nurse practitioners, general practitioners and allied health professionals managing these patients.
  • Part I. The thyroid gland -- Thyroid physiology -- Emil Theodor Kocher -- Karl von Basedow -- Jan Wolff and Israel L. Chaikoff -- Hyperthyroidism and thyroiditis -- Robert James Graves -- Henry Stanley Plummer -- Hakaru Hashimoto -- Fritz de Quervain -- George W. Crile -- Multinodular goiter -- Hugh Spear Pemberton -- Medullary thyroid carcinoma -- John Richard Farndon -- Well-differentiated thyroid cancer: papillary, follicular, and oncocytic (Hürthle) cell cancer -- Karl Hürthle -- Update of the treatment guidelines for well-differentiated thyroid cancer -- Frank Lahey -- Thomas Dunhill -- Part II. The parathyroid glands -- Primary hyperparathyroidism: diagnosis and workup -- Sir Richard Owen -- Fuller Albright -- James Bertram Collip -- Surgical management of hyperparathyroidism -- Felix Mandl -- Oliver Cope -- Parathyroidectomy: postoperative considerations/complications -- Frantis̆ek Chvostek -- Armand Trousseau -- Theodor Billroth -- Part III. The adrenal glands -- Adrenal physiology -- Thomas Addison -- Primary aldosteronism -- Jerome W. Conn -- Cushing's Syndrome -- Harvey Cushing -- J. Aidan Carney -- Pheochromocytoma and paraganglioma -- Charles Horace Mayo -- Arthur M. Shipley -- Emil Zuckerkandl -- Part IV. Neuroendocrine tumors of the pancreas -- Part IV. Neuroendocrine tumors of the pancreas -- Insulinomas -- Sir Fredrick Grant Banting -- Charles Herbert Best -- Allen Oldfather Whipple -- William J. Mayo -- Gastrinoma -- Robert Milton Zollinger -- Edwin H. Ellison -- VIPoma -- John V. Verner Jr. and Ashton B. Morrison -- Glucagonoma -- Small bowel neuroendocrine tumors -- Carcinoid syndrome -- Sigfried Oberndorfer -- Part V. Hereditary endocrine syndromes -- von Hippel-Lindau Disease -- Eugen von Hippel and Arvid Lindau -- Multiple endocrine neoplasia type 1 -- Paul Wermer -- Norman W. Thompson -- Multiple endocrine neoplasia 2 syndromes -- John H. Sipple -- Index.
  • "Few medical fields have enjoyed the explosive growth and continued maturation as the subspecialty of endovascular surgical neuroradiology. In pouring through the literature on all things associated with neurointerventional, I recognized the need to develop a resource that brought focus to the many devices and the techniques and procedures we do. This book does just that: It brings to sharp focus the most current, and up-to-date methods of an ever-changing specialty. It brings this information to you, through the lens of experts in their respective fields by focusing all their research into the textbook that sits before you. The "Clinical Practice" portion of this textbook integrates and translates this theory into a working paradigm that brings benefit to our patients. By focusing on technique and emphasizing complication avoidance and in those unfortunate times when the complication occurs, complication management, your patient benefits"--Provided by publisher.
  • Surgical English 2010
    Methodological Approach to Surgical English -- Surgical Grammar -- Scientific Literature: Writing an Article -- Letters to Editors of Surgical Journals -- Attending an International Surgical Course -- Presenting an Oral Communication in English -- Chairing a Surgical Session -- Typical Mistakes That Surgeons Make When Speaking and Writing in English -- Latin and Greek Terminology -- Acronyms and Abbreviations in Surgery and Medicine -- Glossary of Surgical Terms -- Surgical English by Surgical Specialty -- Taking a Clinical History -- Writing a Surgical Report, Describing a Surgical Technique, Dictating a Report -- Writing a Hospital Discharge Report -- How to Write a Letter Requesting a Visit -- How to Write an International Curriculum Vitae -- Surgical Instruments -- Managing a Surgical Department -- Surgical Conversation Guide -- Conversation Survival Guide -- A Few Words About Effective Communication.
  • The shoulder -- The humerus -- The elbow -- The forearm -- The wrist and hand -- The spine -- Pelvis and acetabulum -- The hip -- The femur -- The knee -- The tibia and fibula -- The ankle and foot -- Approaches for external fixation.
  • Presents coverage that encompasses anatomy and physiology, and evaluation of breast discussions of breast cancer risk and management of breast cancer... equipping you to confidently face any challenge. Addresses hot topics including gynecomastia, neoadjuvant therapy, management of ductal carcinoma in situ, Paget's disease, risk assessment and genetic testing, breast MRI, partial breast irradiation, microarray analysis, and targeted therapies...providing you with a current perspective of this fact changing field. Begins each chapter with a bulleted list of key points, and presents crucial facts in boxes, to help facilitate review. Features abundant illustrations, photographs, and tables that clarify complex concepts. Follows a concise, logical, and consistent organization that makes the material easy to review. Whether studying for the boards or reviewing key material in preparation for a procedure.
  • There is a revolution in new glaucoma surgical techniques. New glaucoma surgical devices are taking precedence in glaucoma surgery, with the new surgeries drastically cutting down on the chances for patient infection as well as higher success rates compared to the older types of surgery. Surgical Innovations in Glaucoma is the only book of its kind written by the top experts in the field, from inventors, clinical trial investigators, and top specialists experienced with the new devices. Written for general ophthalmologists who perform glaucoma surgery, the text walks the reader through the what, where, when, and how of the new glaucoma surgical tools, and includes supplementary online how-to videos for those interested in seeing the latest glaucoma procedures performed with these devices.
  • Supplemental oxygen therapy -- Airway management in the intensive care unit -- Vascular cannulation -- Fluid resuscitation -- Vasoactive amines and inotropic agents -- Shock -- Hemodynamic monitoring -- Acid-base disorders -- Analgesia and sedation -- Neuromuscular blocking agents -- Optimization of the high-risk surgical patient -- Cardiopulmonary resuscitation -- Management of closed head injury -- Spinal cord injuries -- Ischemic stroke -- Hemorrhagic stroke -- Status epilepticus -- Critical illness plyneuorpathy and myopathy -- Management of hypertension in the perioperative period -- Postoperative myocardial infarction -- Management of postoperative arrhythmias -- Acute respiratory failure -- Mechanical ventilation -- Venous thromboembolism -- Fat emulsion syndrome -- Venous air embolism -- Sepsis -- Vascular catherter-related bloodstream infections -- Pneumonia -- Intra-abdominal sepsis -- Evaluation of the febrile patient in the ICU -- Antimicrobial use in surgical intensive care -- Coagulation abnormalities in the critically ill -- Blood products -- Hyperglycemia in the surgical intensive care unit -- Adrenal insufficiency -- Nutrition support in intensive care -- Acute kidney injury -- Renal replacement therapy -- Disorders of electrolytes -- Gastrointestinal bleeding -- Acute pancreatitis -- Trauma -- Burns -- The abdominal compartment syndrome -- Rhabdomyolysis -- Postoperative care of the cardiac surgical patient -- Postoperative care following major vascular surgery -- Postoperative care after bariatric surgery -- Care of the organ donor -- Postoperative care of the heart transplant patient -- Postoperative care of the lung-transplant patient -- Postoperative care of the liver-transplant patient -- Postoperative care of the pancreas-transplant recipient -- Management of the critically ill geriatric patient -- Alcohol withdrawal in the surgical patient: prevention and treatment -- Ethics and the end-of-life care -- Scoring systems and outcome prediction -- Improving the intensive care unit -- Continuing education in critical care medicine.
  • Surgical Management of Benign Esophageal Disorders: The ""Chicago Approach"" covers all stages of the diagnosis and treatment of the most common benign esophageal disorders in a concise and easy-to-read format. Indications, patient preparation, operative techniques, and strategies for avoiding and managing complications are included and based both on evidence-based data and the experience of the most famous esophageal surgeons in the United States and abroad. Each chapter includes a summary of the current management strategy for the disease process, and a review of current state of the art techniques provided by world leaders on esophageal disease, surgeons and gastroenterologists alike.
  • Microsurgical principles for anterior circulation aneurysms -- Treatment of ruptured cerebral aneurysms: clip and coil, not clip versus coil -- Distal anterior cerebral artery aneurysms -- Treatment of complex intracranial aneurysms of anterior circulation using multiple clips -- Overview of spontaneous cervicocephalic arterial dissection in Japan -- Incidence of intracranial arterial dissection in non-emergency outpatients complaining of headache: preliminary investigation with MRI/MRA examinations -- A study of vertebrobasilar artery dissection with subarachnoid hemorrhage -- Surgical treatment of intracranial VA dissecting aneurysm -- Management of spontaneous dissection of the cervical carotid artery -- Natural history of arteriovenous malformations: presentation, risk of hemorrhage and mortality -- Present state of microneurosurgery of cerebral arteriovenous malformations -- Management of dural arteriovenous fistulas: Helsinki and Kuopio experience -- The rationale behind "a randomized trial of unruptured brain AVMs" (ARUBA) -- Posterior circulation EC-IC bypass via supracerebellar transtentorial SCTT approach applied in a young patient with congenital multiple occlusive cerebrovascular anomalies: case report and technical note -- Superficial temporal artery-to-middle cerebral artery anastomosis with encephalo-duro-myo-synangiosis as a modified operative procedure for moyamoya disease -- Long-term results of carotid endarterectomy and carotid stenting -- Application of microscope integrated indocyanine green video-angiography during microneurosurgical treatment of intracranial aneurysms: a review -- Principles of neuroanesthesia in stroke surgery -- Prevention of symptomatic vasospasm by continuous cisternal irrigation with mock-CSF containing ascorbic acid and Mg2+.
  • 1. Complete Transposition of the Great Arteries 2. Corrected Transposition of the Great Arteries -- 3. Left Ventricular Outflow Tract Anomalies -- 4. Tetralogy of Fallot -- 5. Ebstein's Anomaly.
  • Recent advances in cardiac allotransplantation / John Adams Jarcho and James C. Fang -- Surgical revascularization in the management of heart failure and ischemic left ventricular dysfunction / Jeffrey J. Teuteberg and James C. Fang -- Aortic valve surgery with severe left ventricular dysfunction / Blasé A. Carabello -- Mitral valve surgery with severe left ventricular dysfunction / Vinay Badhwar and Steven F. Bolling -- Tricuspid valve surgery in right heart failure / James P. Greelish ... [et al.] -- Pacing in heart failure / Uday N. Kumar, Teresa De Marco, and Leslie A. Saxon -- Left ventricular assist devices / Paul L. DiGiorgi, Yoshifumi Naka, and Mehmet C. Oz -- Left ventricular volume reduction surgery for idiopathic dilated cardiomyopathy / Richard Lee ... [et al.] -- Surgical management of hypertrophic cardiomyopathy / William G. Williams ... [et al.] -- Dynamic cardiomyoplasty and new prosthetic LV girdling devices / Michael A. Acker -- Xenotransplantation / Joren C. Madsen and Ruediger Hoerbelt -- Left ventricular reconstruction for ischemic heart failure / Vincent Dor -- The total artificial heart in the surgical management of congestive heart failure / Jack G. Copeland, Francisco A. Arabia, and Richard G. Smith.
  • Injectable intraocular corticosteroids / Paul A. Kurz ... [et al.] -- Intraocular corticosteroid implants / David Callanan -- Noncorticosteroid intraocular drug therapy / Francine Behar-Cohen, Jean-Louis Bourges -- Therapeutic vitrectomy for noninfectious uveitis / Kathrin Greiner, Andrew D. Dick -- Cryotherapy and laser for intermediate uveitis / Javier A. Montero, Jose M. Ruiz-Moreno -- Surgery for band keratopathy / Ruth Lapid-Gortzak ... [et al.] -- Selection of surgical technique for complicated cataract in uveitis / Mauricio Miranda, Jorge L. Alió -- Perioperative medical management / Manfred Zierhut, Peter Szurman -- Pars plana lensectomy / Emilio Dodds -- Extracellular extraction by phacoemulsification / Antoine P. Brézin, Dominique Monnet -- Selection of intraocular lenses : materials, contraindications, secondary implants / Gerd U. Auffarth -- Management of posterior synechiae, peripheral anterior synechiae, iridocorneal adhesions, and iridectomy / Yosuf El-Shabrawi -- Complications post cataract surgery in the uveitic eye / Marie-José Tassignon, Dimitrios Sakellaris -- Cataract surgery in childhood uveitis / Arnd Heiligenhaus, Carsten Heinz, Bahram Bodaghi -- Surgical management of uveitis-induced angle-closure glaucoma / Kaweh Mansouri, Tarek Shaarawy -- Surgical management of open-angle glaucoma associated with uveitis / Herbert P. Fechter, Richard K. Parrish II -- Cyclodestructive procedures / Torsten Schlote -- Macular surgery for posterior segment complications of uveitis / Janet L. Davis -- Surgical treatment of retinal vasculitis with occlusion, neovascularization or traction / Jose M. Ruiz-Moreno, Javier A. Montero -- Surgical treatment of uveitic commplications : retinal detachment / Heinrich Heimann -- Surgical management of ocular hypotony / Mark Hammer, W. Sanderson Grizzard -- Anterior chamber tap and aqueous humor analysis / Uwe Pleyer, Justus G. Garweg -- Surgery for the diagnosis of uveitis-anterior segment biopsy / Bahram Bodaghi -- Diagnostic vitrectomy / Christoph M.E. Deuter, Sabine Biester, Karl Ulrich Bartz-Schmidt -- Choroidal biopsy / Christoph M.E. Deuter, Sabine Biester, Karl Ulrich Bartz-Schmidt -- Retinal biopsy / Janet L. Davis.
  • Surgical Management of Pain, Second Edition, is a completely updated state-of-the-art reference on neurosurgical pain management. This new edition is in full color and includes the following sections: Anatomic and Physiologic Foundations for Nociceptive and Neuropathic Pain, Pain Medicine, Pain Diagnoses, Surgical Procedures for Pain, and New Directions for Pain Surgery. The chapters in the book focus on procedures that are currently performed by neurosurgeons to relieve pain. Key Features: Emphasizes best evidence treatment options free online access to videos demonstrating surgical technique.
  • Epidemiology, risk factors, and social impact of pelvic organ prolapse / Corina Schmid and Christopher F. Maher -- Surgical anatomy of the pelvis and the anatomy of pelvic support / Mickey Karram -- Preoperative evaluation and staging of patients with pelvic organ prolapse / Mickey Karram -- Indications and techniques for vaginal hysterectomy and vaginal trachelectomy in patients with pelvic organ prolapse / Mickey Karram -- Surgical procedures to suspend a prolapsed uterus / Christopher F. Maher and Mickey Karram -- Robot-assisted laparoscopic colpo- and cervicosacropexy with the da Vinci Surgical System / Catherine A. Matthews -- Surgical management of apical vaginal prolapse / Christopher Maher and Mickey Karram -- Surgical management of anterior vaginal wall prolapse / Christopher F. Maher and Mickey Karram -- Surgical correction of posterior pelvic floor defects / Mickey Karram -- Obliterative procedures for pelvic organ prolapse / Janelle Evans and Mickey Karram -- Surgery for pelvic organ prolapse : avoiding and managing complications / Mickey Karram and Christopher F. Maher.
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    Pathogenesis of acute spinal cord injury and theoretical bases of neurological recovery / Arun Paul Amar -- Pharmacotherapy for spinal cord injury / Steven Casha, Joseph Silvaggio, R. John Hurlbert -- Prehospital and emergency department management of spinal cord injury / Stuart P. Swadron, Danny L. Chang, Brian Wilbur -- Radiographic workup of spinal cord injury / Nestor R. Gonzalez, Larry T. Khoo, Richard G. Fessler -- Controversies in surgical decompression : timing of decompressive surgery of the spinal cord / Mark S. Gerber, Volker K.H. Sonntag -- Biomechanics of spinal column failure / Eric P. Roger, G. Alexander Jones, Edward C. Benzel -- Principles of spine stabilization / G. Alexander Jones, Eric P. Roger, Edward C. Benzel -- Controversies in the management of cervical spinal cord injury / Paul G. Matz, Mark N. Hadley -- Surgical decision-making in spinal fracture dislocations / Robert G. Watkins -- Spinal cord injury in pediatric patients / Philipp R. Aldana, Douglas L. Brockmeyer -- Management of penetrating spinal cord injury / K. Anthony Kim, Arun Paul Amar, Michael L. Levy -- Traumatic vascular injury to the cervical spine / Michael L. DiLuna, Arun Paul Amar -- Intraoperative neurophysiologic monitoring during spinal surgery / Indro Chakrabarti, Jerry Larson, Gordon L. Engler, Steven L. Giannotta -- Surgery after the acute phase of traumatic spinal cord injury / Michael Y. Wang, Barth A. Green.
  • A who's who in this challenging field brings you state-of-the-art approaches to the full range of surgical management options, including reconstructive procedures, for the pediatric and adult patient with spinal deformity. Experts discuss the course of treatment for patients in different age groups and take into consideration the extent of the curve at the time of diagnosis and during follow-up, the patient's stage of bone growth, the amount of pain and deformity associated with the condition, and the patient's willingness and ability to withstand surgery. Plus, a section on general information such as practical surgical anatomy, imaging, applied biomechanics, and instrumentation helps you approach each patient more effectively. The included DVD helps you perfect your technique with narrated surgical procedures. Emphasizes technical skills and surgical decision making, including pearls, pitfalls, and illustrative case studies, offering you expert advice on technically challenging surgeries. Provides the very latest information on minimally invasive endoscopic and mini-open approaches to broaden your surgical options and minimize post-operative complications. Discusses peri-operative considerations, including anesthesia, blood loss management, bone graft and fusion enhancement, neural monitoring, and complications, keeping you prepared for any event. Presents full-color line artwork of surgical procedures as well as diagnostic and clinical photographs for superb visual guidance. Offers a consistent format throughout and a full-color design for ease of reference. Website includes a video library of narrated surgical procedures to help you master your technique.
  • What is mentoring and who is a mentor? -- Why surgical mentoring is important and evidence that it makes a difference -- What are the qualities of an outstanding surgical mentor? -- How and where should surgical mentoring be performed? -- Mentoring women surgeons -- Mentoring international medical graduates -- How to develop faculty mentors -- How to choose a mentor -- Future directions.