search indicatorNeed Help? Search Tools



  • Bioinformatics in membrane protein analysis / Bengt Persson -- Prokaryotic membrane transport proteins / Joanne Clough ... [et al.] -- Membrane protein production strategies for structural genomics / Said Eshaghi and Par Nordlund -- Refolding of membrane proteins for large-scale production / Hans Kiefer, Thomas Ostermann, Monika Bahner -- Crystallization of membrane proteins / Alastair T. Gardiner, June Southall, and Richard J. Cogdell -- Signaling through membrane proteins / J. Robert Bostwick and Deborah S. Hartman -- Expression of membrane proteins in yeasts / Christoph Reinhart, Christoph Krettler -- Expression of functional membrane proteins in the baculovirus-insect cell system / Giel J.C.G.M. Bosman and Willem J. de Grip -- Expression of membrane proteins in mammalian cells / Kenneth Lundstrom -- Solubilization and purification of membrane proteins / Bernadette Byrne and Mika Jormakka -- Fluorescent labelling of membrane proteins in living cells / Ruud Hovius ... [et al.] -- Membrane protein NMR / Xiang-Qun (Sean) Xie -- Miniaturization of structural biology technologies--from expression to biophysical analyses / Enrique Abola, Peter Kuhn, and Raymond C. Stevens -- Electron microscopy and atomic force microscopy of reconstituted membrane proteins / Andreas Engel -- -- Structural genomics networks for membrane proteins / Kenneth Lundstrom -- Molecular modelling of membrane proteins / Slawomir Filipek and Anna Modzelewska -- Towards structural bases for GPCR ligand-binding / Sabrina A. Beretta ... [et al.].
  • Print Material
    Bioinformatics in membrane protein analysis / Bengt Persson -- Prokaryotic membrane transport proteins / Joanne Clough ... [et al.] -- Membrane protein production strategies for structural genomics / Said Eshaghi and Pär Nordlund -- Refolding of membrane proteins for large-scale production / Hans Kiefer, Thomas Ostermann, Monika Bähner -- Crystallization of membrane proteins / Alastair T. Gardiner, June Southall, and Richard J. Cogdell -- Signaling through membrane proteins / J. Robert Bostwick and Deborah S. Hartman -- Expression of membrane proteins in yeasts / Christoph Reinhart, Christoph Krettler -- Expression of functional membrane proteins in the baculovirus-insect cell system / Giel J.C.G.M. Bosman and Willem J. de Grip -- Expression of membrane proteins in mammalian cells / Kenneth Lundstrom -- Solubilization and purification of membrane proteins / Bernadette Byrne and Mika Jormakka -- Fluorescent labelling of membrane proteins in living cells / Ruud Hovius ... [et al.] -- Membrane protein NMR / Xiang-Qun (Sean) Xie -- Miniaturization of structural biology technologies--from expression to biophysical analyses / Enrique Abola, Peter Kuhn, and Raymond C. Stevens -- Electron microscopy and atomic force microscopy of reconstituted membrane proteins / Andreas Engel -- -- Structural genomics networks for membrane proteins / Kenneth Lundstrom -- Molecular modelling of membrane proteins / Slawomir Filipek and Anna Modzelewska -- Towards structural bases for GPCR ligand-binding / Sabrina A. Beretta ... [et al.].
  • Complex I (NADH:ubiquinone oxidoreductase) is the first and largest enzyme of the respiratory chain in mitochondria and plays a central role in cellular energy production. Complex I dysfunction has been implicated in many human neurodegenerative diseases, including Parkinson's. Mutations in complex I subunits are among the most common human genetic disorders known. Until recently, in the absence of structural information, complex I was the least understood enzyme of the respiratory chain. The mechanism by which it couples electron transfer between NADH and quinone to the translocation of protons across the membrane was a complete enigma. Recent years have been marked by spectacular progress in the elucidation of complex I's structure, finally allowing the interpretation of a wealth of data accumulated in about 50 years since the discovery of the enzyme. Understanding of the mechanism of this large molecular machine, involving long-range conformational changes, is beginning to emerge. This book is the first devoted entirely to complex I. It contains chapters written by leaders in the field, covering a wide range of topics from the structure of the complex, properties of its many redox centers, subunit composition, mutagenesis studies, evolution of the enzyme and on to the current understanding of the coupling mechanism and the molecular basis for human pathologies. Features: - Concise and authoritative review of current state-of-the-art in research on respiratory complex I - The first book entirely devoted to complex I, a central enzyme in bioenergetics - Recent breakthroughs in structure elucidation finally allow understanding of the mechanism - Mutations leading to common and severe human disorders are discussed.
  • Target selection for structural genomics : an overview / Russell L. Marsden and Christine A. Orengo -- A general target selection method for crystallographic proteomics / Gautier Robin ... [et al.] -- Target selection : triage in the structural genomics battlefield / James Raftery -- Data management in structural genomics : an overview / Sabrina Haquin ... [et al.] -- Data deposition and annotation at the worldwide protein data bank / Shuchismita Dutta ... [et al.] -- Prediction in protein disorder / Zsuzsanna Dosztányi and Peter Tompa -- Protein domain prediction / Helgi Ingolfsson and Golan Yona -- Protein structure modeling with MODELLER / Narayanan Eswar ... [et al.] -- High throughput cloning with restriction enzymes / Volker Sievert, Asgar Ergin, and Konrad Bussow -- Automated recombinant protein expression screening in Escherichia coli / Didier Busso ... [et al.] -- From no expression to high-level soluble expression in Escherichi coli by screening a library of the target proteins with randomized N-termini / Kyoung Hoon Kim ... [et al.] -- Application of high-throughput methodologies to the expression of recombinant proteins in E. coli / Yoav Peleg and Tamar Unger -- A high throughput platform for eukaryotic genes / Yunjia Chen ... [et al.] -- High throughput production of recombinant human proteins for crystallography / Opher Gileadi ... [et al.] -- Assembly of protein complexes by coexpression in prokaryotic and eukaryotic hosts : an overview / Anastassis Perrakis and Christophe Romier -- Cell-free protein synthesis for analysis by NMR spectroscopy / Margit A. Apponyi ... [et al.] -- A medium or high throughput protein refolding assay / Nathan P. Cowieson ... [et al.] -- Structural proteomics of membrane proteins : a survey of published techniques and design of a rational high throughput strategy / Melissa Swope Willis and Christopher M. Koth -- Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering / Joanne E. Nettleship ... [et al.] -- High throughput methods for analyzing transition metals in proteins on a microgram scale / Anelia Atanassova, Martin Högbom, and Deborah B. Zamble -- High throughput screening of purified proteins for enzymatic activity / Michael Proudfoot ... [et al.] -- Strategies for improving crystallization success rates / Rebecca Page -- Protein crystallization in restricted geometry : advancing old ideas for modern times in structural proteomics / Joseph D. Ng, Raymond C. Stevens, and Peter Kuhn -- Fluorescence approaches to growing macromolecule crystals / Marc Pusey, Elizabeth Forsythe, and Aniruddha Achari -- Efficient macromoleular crystallization using microfluidics and randomized design of screening reagents / Andrew P. May and Brent W. Segelke -- Increasing protein crystallization screening success with heterogeneous nucleating agents / Anil S.Thakur ... [et al.] -- High throughput pH optimization of protein crystallization / Ran Meged, Orly Dym, and Joel L. Sussman -- Automated structure solution with the PHENIX suite / Peter H. Zwart ... [et al.] -- NMR screening for rapid protein characterization in structural proteomics / Justine M. Hill -- Microcoil NMR spectroscopy : a novel tool for biological high throughput NMR spectroscopy / Russell E. Hopson and Wolfgang Peti -- Protein structure determination using a combination of cross-linking, mass spectrometry, and molecular modeling / Dmitri Mouradov ... [et al.] -- Structural genomics of minimal organisms : pipeline and results / Sung-Hou Kim ... [et al.] -- Structural genomics of pathogenic protozoa : an overview / Erkang Fan ... [et al.] -- High throughput crystallography at SGC Toronto : an overview / Alexey Bochkarev and Wolfram Tempel -- The structural biology and genomics platform in Strasbourg : an overview / Didier Busso, Jean-Claude Thierry, and Dino Moras -- Bacterial structural genomics initiative : overview of methods and technologies applied to the process of structure determination / Miroslaw Cygler ... [et al.] -- High-throughput protein production and crystallization at NYSGXRC / Michael J. Sauder ... [et al.] -- Overview of the pipeline for structural and functional characterization of macrophage proteins at the University of Queensland / Weining Meng ... [et al.] -- Structural genomics of the bacterial mobile metagenome : an overview / Andrew Robinson ... [et al.].
  • Print Material
  • Principles of protein structure and function -- A brief history of protein disorder -- Indirect techniques for recognizing and characterizing protein disorder -- Hydrodynamic techniques -- Spectroscopic techniques for characterizing disorder -- Nuclear magnetic resonance -- Proteomic approaches for the identification of IDPs -- IDPs under conditions approaching in vivo -- Prediction of disorder -- Structure of IDPs -- Biological processes enriched in disorder -- Molecular functions of disordered proteins -- Evolution and prevalence of disorder -- Extension of the structure-function paradigm -- Structural disorder and disease.
  • Part I. Structure and ligands of NCAM. -- Structural biology of NCAM / Vladislav Soroka, Christina Kasper, Flemming M. Poulsen. -- Extracellular protein interactions mediated by the neural cell adhesion molecule, NCAM: heterophilic interactions between NCAM and cell adhesion molecules, extracellular matrix proteins, and viruses / Janne Nielsen, Nikolaj Kulahin, Peter S. Walmod. -- Intracellular (intracelluar) ligands of NCAM / Bettina Buttner, Rudiger horstkorte. -- Role of ATP in the regulation of NCAM function / Martin V. Hubschmann, Galina Skladchikova. -- Part II. NCAM and plysialic acid. -- Polysialylation of NCAM / Herbert Hildebrandt, Martina Muhlenhoff, Rita Gerardy-Schahn. -- Structural basis for the polysialylation of the neural cell adhesion molecule / Karen J. Colley. -- Role of PSA-NCAM in adult neurogenesis / Eduardo Gascon, Laszlo Vutskits, Jozsel Zoltan Kiss. -- Use of PSA-NCAM in repair of the central nervous system / Abderrahman El Maarouf, Urs Rutishauser. -- Part III. NCAM-mediated signal transduction. -- Signaling pathways involved in NCAM-induced neurite outgrowth / Dorte Kornerup Ditlevsen, Kateryna Kolkova. -- Role of the growth-associated protein GAP-43 in NCAM mediated neurite outgrowth / Irina Korshunova, Mark Mosevitski. -- Neural cell adhesion molecule NCAM and lipid rafts / Gro Klitgaard Povlsen, Dorte Kornerup Ditlevsen. -- Neural cell adhesion molecule and epidermal growth factor receptor: signaling crosstalk / Gro Klitgaard Polvsen. -- Part IV. NCAM metabolism. -- Biosynthesis of NCAM / Kateryna Kolkova. -- Soluble NCAM / Thomas Secher. -- Part V. NCAM, synapses, emotions, and memory. -- Role of NCAM in spine dynamics and synaptogenesis / D. Muller, P. Mendez, M. DeRoo, P. Klauser, S. Steen, and L. Poglia. -- NCAM in long-term potentiation and learning / Barbara P. Hartz, Lars Christian B. Roon. -- Role of NCAM in emotion and learning / Lisa Conboy, Reto Bisaz, Kamila Markram, Carment Sandi. -- Part VI. NCAM in disease. -- NCAM in neuropsychiatric and neurodegenerative disorders / Leann H. Brennaman, Patricia F. Maness. -- Neural cell adhesion molecule in cancer: expression and mechanisms / Silvia Zecchini, Ugo Caallaro. -- Part VII. Pharmacology of NCAM: NCAM mimetics. -- NCAM mimetic peptides: an update / Vladimir Berezin, Elisabeth Bock. -- Synthetic NCAM-derived ligands of the fibroblast growth factor receptor / Stine maria Hansen, Shizhong Li, Elisabeth Bock, Vladimir Berezin. -- Dendritic spine and synapse morphological alterations induced by neural cell adhesion molecule mimetic / Michael Stewart, Victor Popov, Nikolai Medvedev, Paul Giabbon, Nicola Corbett, Igor Kraev, Heather Davies. -- Part VIII. Orthologs and paralogs of NCAM. -- Fasciclin II: the NCAM ortholog in Drosophila melanogaster / Lars V. Kristiansen, Michael Hortsch. -- Neural cell adhesion molecule NCAM2/OCAM/RNCAM, a close relative to NCAM / Nikolaj Kulahin, Peter S. Walmod. -- Part IX. Conclusion. -- Honoring Dr. Elisabeth Bock / Vladimir Berezin.
  • This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdo
  • Chapter 1. Lipid structure -- Chapter 2. The mesomorphic phase behavior of lipid bilayers -- Chapter 3. Lipid bilayer interdigitation -- Chapter 4. The dynamics of membrane lipids -- Chapter 5. Nonlamellar lipid phases -- Chapter 6. The forces between interacting bilayer membranes and the hydration of phospholipid assemblies -- Chapter 7. The roles of cholesterol in the biology of cells -- Chapter 8. Lipid membrane fusion -- Chapter 9. Membrane rafts -- Chapter 10. Passive and facilitated transport -- Chapter 11. Membrane protein dynamics: rotational dynamics -- Chapter 12. Translational diffusion of membrane proteins -- Chapter 13. Inorganic anion transporter AE1 -- Chapter 14. The structures of G-protein coupled receptors -- Chapter 15. Role of membrane lipids in modulating the activity of membrane-bound enzymes -- Chapter 16. Viral fusion mechanisms.
  • Print Material
  • The Mastigont System in Trichomonads / Marlene Benchimol -- Subpellicular Microtubules in Apicomplexa and Trypanosomatids / Wanderley de Souza and Marcia Attias -- Flagellum Structure and Function in Trypanosomes / Johanna Buisson and Philippe Bastin -- The Flagellar Pocket of Trypanosomatids: A Critical Feature for Cell Morphogenesis and Pathogenicity / Paul G. McKean and Keith Gull -- Reservosomes of Trypanosoma cruzi / Narcisa Leal Cunha-e-Silva, Celso Sant'Anna, Miria G. Pereira and Wanderley de Souza -- Megasomes in Leishmania / Diane McMahon-Pratt, Tania Ueda-Nakamura and Yara M. Traub-Csekö -- Organelles and Trafficking in Entamoeba histolytica / Sherri S. Smith and Nancy Guillen -- Secretory Organelles in Apicomplexa / Jean François Dubremetz -- Secretory Events During Giardia Encystation / Fernando D. Rivero, Dana Müller and Hugo D. Lujan -- The Remarkable Mitochondrion of Trypanosomes and Related Flagellates / Julius Lukeš, Hassan Hashimi, Zdeněk Verner and Zdeňka Čičová -- The Apicoplast: An Ancient Algal Endosymbiont of Apicomplexa / Swati Agrawal, Sethu Nair, Lilach Sheiner and Boris Striepen -- The Glycosome of Trypanosomatids / Fred R. Opperdoes -- Calcium Homeostasis and Acidocalcisomes in Trypanosoma cruzi / Paul Ulrich, Roxana Cintrón and Roberto Docampo.
  • Native purification and analysis of long RNAs -- Characterizing RNA excited states using NMR relaxation -- Quantifying nucleic acid ensembles with x-ray scattering interferometry -- 2-aminopurine fluroescence as a probe of local RNA structure and dynamics and global folding -- Mod-seq: a high-throughput method for probing RNA secondary structure -- Reproducible analysis of sequencing-based RNA structure probing data with user-friendly tools -- Computational methods for RNA structure validation and improvement -- Structures of large RNAs and RNA-protein complexes: toward structure determination of riboswitches -- One, two, three, four! How multiple RRMs read the genome sequence -- Combining NMR and EPR to determine structures of large RNAs and protein-RNA complexes in solution -- Structural analysis of protein-RNA complexes in solution using NMR paramagnetic relaxation enhancements -- Resolving individual components in protein-RNA complexes using small-angle x-ray scattering experiments -- Small-anlge neurtron scattering for structural biology of protein-RNA complexes -- Strudying RNA-protein interactions of Pre-mRNA complexes by mass spectrometry -- RNA bind-n-Seq: measuring the binding affinity landscape of RNA-binding proteins -- Using molecular simulation to model high-resolution Cryo-EM reconstructions -- In vitro reconstitution and crystallization of Cas9 endonuclease bound to a guide RNA and a DNA target -- Single-molecule pull-down FRET to dissect the mechanisms of biomolecular machines -- Single-molecule imaging of RNA splicing in live cells.
  • Print Material
  • Print Material
    I. Untersuchung über das Rachitisvorkommen in einem norwegischen Binnental.
  • Print Material
  • Print Material
    v. 1. Evaluation of treatments.--v. 2. Research on patients, treatments, and outcomes.--v. 3. Further studies of drug users, treatment typologies, and assessment of outcomes during treatment in DARP.--v. 4. Evaluation of treatment outcomes for 1971-1972 DARP admission cohort.--v. 5. Evaluation of treatment outcomes for 1972-1973 DARP admission cohort.
  • This volume systematically reviews the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as oxidative stress, in the pathology of Alzheimer's disease. It describes the most current diagnostic tools, laboratory methods and technology, and suggests ways of prevention and treatment to emphasize the concept of the bench-to-bedside approach. Studies on Alzheimer's Disease provides thorough coverage of emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents, and several more relevant aspects. In addition, this book promotes the concept of using biomarkers representative of oxidative stress reactions and free-radical damage, as well as describing the effects of antioxidants in treating disease in clinical trials. This content is invaluable to both researchers studying the development of and clinicians treating patients with a diagnosis of Alzheimer's Disease.
  • Joint diseases are a major public health concern. Reactive oxygen species are mediators in pathways associated with joint tissue injury. Oxidative Stress in Applied Basic Research and Clinical Practice: Studies on Arthritis and Joint Disorders provides background to understanding the role of reactive oxygen species in joint diseases, as well as therapeutic strategies for their regulation. International experts discuss recent advances on experimental and clinical data focused on free radical-mediated mechanisms of disease. The book also addresses the protective role of antioxidants against the insult of reactive oxygen species in rheumatic diseases.
  • The Evolving Concept of Oxidative Stress / Denise de Castro Fernandes, Diego Bonatto and Francisco R.M. Laurindo -- Mechanisms of Redox Signaling in Cardiovascular Disease / Rebecca L. Charles, Joseph R. Burgoyne and Philip Eaton -- Reactive Oxygen and Nitrogen Species in Cardiovascular Differentiation of Stem Cells / Heinrich Sauer and Maria Wartenberg -- Reactive Oxygen Species (ROS) and the Sensory Neurovascular Component / Rabea Graepel, Jennifer Victoria Bodkin and Susan Diana Brain -- Mitochondrial Reactive Oxygen Species in Myocardial Pre- and Postconditioning / Ariel R. Cardoso, Bruno B. Queliconi and Alicia J. Kowaltowski -- Coenzyme Q9/Q10 and the Healthy Heart / Samarjit Das, Somak Das and Dipak K. Das -- Oxidative and Proteolytic Stress in Homocysteine-Associated Cardiovascular Diseases / Karni S. Moshal, Munish Kumar, Neetu Tyagi, Paras Kumar Mishra and Saumi Kundu, et al. -- Functional Studies of NADPH Oxidases in Human Vasculature / Tomasz J. Guzik -- Relationship of the CYBA Gene Polymorphisms with Oxidative Stress and Cardiovascular Risk / Guillermo Zalba and Javier Díez -- Redox-Related Genetic Markers of Cardiovascular Diseases / Christian Delles and Anna F. Dominiczak -- NADPH Oxidases and Blood-Brain Barrier Dysfunction in Stroke / Timo Kahles, Sabine Heumüller and Ralf P. Brandes -- Smoking-Induced Oxidative Stress in the Pathogenesis of Cardiovascular Diseases / David Bernhard -- Oxidative Stress in Vascular Aging / Anna Csiszar and Zoltan Ungvari -- Oxidative Stress and Cardiovascular Disease in Diabetes Mellitus / Divya Gupta, Kathy K. Griendling and W. Robert Taylor -- Reactive Oxygen Species, Oxidative Stress, and Hypertension / Rhian M. Touyz, Andreia Chignalia and Mona Sedeek -- Peripartum Cardiomyopathy: Role of STAT-3 and Reactive Oxygen Species / Denise Hilfiker-Kleiner, Arash Haghikia and Andres Hilfiker -- Oxidative Stress and Inflammation after Coronary Angiography / Raymond Farah -- Oxidative Stress in Cardiac Transplantation / Galen M. Pieper and Ashwani K. Khanna -- Oxidative Stress and Atrial Fibrillation / Ali A. Sovari and Samuel C. Dudley -- Oxidative Stress and the Antioxidative Capacity in Myocardial Infarction / Yao Sun -- Oxidative Stress and Redox Signalling in Cardiac Remodelling / Min Zhang, Alex Sirker and Ajay M. Shah -- Oxidative Stress and Cardiovascular Fibrosis / Subramaniam Pennathur, Louise Hecker and Victor J. Thannickal -- Oxidative Risk Factors for Cardiovascular Disease in Women / Manuela Gago-Dominguez, Xuejuan Jiang and Jose Esteban Castelao -- Protective Effects of Food on Cardiovascular Diseases / Alfonso Giovane and Claudio Napoli -- Novel Synthetic Antioxidants and Nitrated Lipids: From Physiology to Therapeutic Implications / Gloria V. López and Homero Rubbo -- Thioredoxin in the Cardiovascular System-Towards a Thioredoxin-Based Antioxidative Therapy / Cameron World and Bradford C. Berk -- The Protective Effect of Melatonin on the Heart / Amanda Lochner -- Exercise-Induced Cardioprotection: Overview with an Emphasis on the Role of Antioxidants / Karyn L. Hamilton and John C. Quindry -- Antioxidative Properties of Statins in the Heart / Oliver Adam and Ulrich Laufs.
  • Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of -crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina. A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.
  • Print Material
  • Evidence-based information plays a critical role in clinical practice decisions. Secondary sources are often unreliable; it.s up to the student, then, to critically assess peer-reviewed research literature. Using a highly structured yet accessible method, this text teaches students to critically analyze research from primary sources. Step-by-step approach. learn to recognize a meaningful study, clues to potential study flaws, and ways to apply solid evidence in clinical practice. Simple 6-point framework. learn to evaluate studies in terms of the authors trademark mnemonic device, M.A.A.R.I.E. (Methods, Assignment, Assessment, Results, Interpretation and Extrapolation). Unique Learning Aids - question checklists, real-world scenarious, flaw-catching exercises and more help to make complex concepts easy to grasp.
  • "This pocket-sized book is a quick-reference practical guide for physicians who deal with patients with subarachnoid hemorrhage or intracranial aneurysms outside the hospital. It describes briefly the epidemiology of subarachnoid hemorrhage, the early recognition and clinical course, and in more depth the aftercare, residual symptoms and deficits. The prognosis and management in the long term are discussed in detail. It also provides information on the counselling and treatment of patients with unruptured intracranial aneurysms. Subarachnoid Hemorrhage in Clinical Practice is aimed at general practitioners and family physicians and will also be informative for other specialists such as rehabilitation physicians, nursing home physicians, and physicians working for health insurance companies. It may also be of interest to patients, relatives, and paramedics."--Back cover.
  • Defines the functional neuroanatomy of cortical-subcortical circuitries and establishes that since structure is related to function, what the basal ganglia and cerebellum do for movement they also do for cognition and emotion. This book also examines neuropsychological assessment.
  • Print Material
    There are 9 vols. in the Subject section; 5 vols. in the Biographical section and 4 vols. in the Topographical section. This series reproduces the card subject catalog of the library and includes a cumulation of Current Work in the History of Medicine (No. 6451.1). Material is included until 1977.
  • Subjective well-being refers to how people experience and evaluate their lives and specific domains and activities in their lives. This information has already proven valuable to researchers, who have produced insights about the emotional states and experiences of people belonging to different groups, engaged in different activities, at different points in the life course, and involved in different family and community structures. Research has also revealed relationships between people's self-reported, subjectively assessed states and their behavior and decisions. Research on subjective well-being has been ongoing for decades, providing new information about the human condition. During the past decade, interest in the topic among policy makers, national statistical offices, academic researchers, the media, and the public has increased markedly because of its potential for shedding light on the economic, social, and health conditions of populations and for informing policy decisions across these domains. Subjective Well-Being: Measuring Happiness, Suffering, and Other Dimensions of Experience explores the use of this measure in population surveys. This report reviews the current state of research and evaluates methods for the measurement. In this report, a range of potential experienced well-being data applications are cited, from cost-benefit studies of health care delivery to commuting and transportation planning, environmental valuation, and outdoor recreation resource monitoring, and even to assessment of end-of-life treatment options. Subjective Well-Being finds that, whether used to assess the consequence of people's situations and policies that might affect them or to explore determinants of outcomes, contextual and covariate data are needed alongside the subjective well-being measures. This report offers guidance about adopting subjective well-being measures in official government surveys to inform social and economic policies and considers whether research has advanced to a point which warrants the federal government collecting data that allow aspects of the population's subjective well-being to be tracked and associated with changing conditions.
  • I. Foundations -- Historical perspectives / David F. Musto -- Epidemiology / Charles Winick and R.L. Norman -- U.S. federal drug policy / Mathea Falco -- II. Determinants of substance abuse and dependence -- Genetic factors in the risk for substance use disorders / Show W. Lin and Robert M. Anthenelli -- Brain-reward mechanisms / Eliot L. Gardner -- Psychodynamics / Edward J. Khantzian, Lance Dodes, Nancy M. Brehm -- Sociocultural issues / Bruce D. Johnson and Andrew Golub -- III. Substances of abuse -- Alcohol: neurobiology / Stephen L. Boehm II, C. Fernando Valenzuela, R. Adron Harris -- Alcohol: clinical aspects / Bankole A. Johnson and Nassima Ait-Daoud -- Opiates: neurobiology / Eric J. Simon -- Opiates: clinical aspects / Clifford M. Knapp, Domenic A. Ciraulo, and Jerome Jaffe -- Cocaine and crack: neurobiology / Martin Repetto and Mark S. Gold -- Cocaine and crack: clinical aspects / Mark S. Gold and William S. Jacobs -- The Neurobiology of marijuana / Sandra P. Welch -- Marihuana: clinical aspects / Lester Grinspoon, James B. Bakalar, and Ethan Russo -- Amphetamines and other stimulants / George R. King and Everett H. Ellinwood, Jr. -- Sedative-hypnotics / Donald R. Wesson, David E. Smith, Walter Ling, and Richard B. Seymour -- Hallucinogens / Robert N. Pechnick and J. Thomas Ungerleider -- Phencyclidine (PCP) / Stephen R. Zukin, Zili Sloboda, and Daniel C. Javitt -- Inhalants / Charles W. Sharp and Neil L. Rosenberg -- Designer drugs / John P. Morgan -- MDMA / Charles S. Grob and Russell E. Poland -- Nicotine / Joy M. Schmitz and Katherine A. DeLaune -- Caffeine / Laura M. Juliano and Roland R. Griffiths -- Anabolic-androgenic steroids / Elyse R. Eisenberg and Gantt P. Galloway -- Prescription opiate abuse / Walter Ling, Donald R. Wesson, and David E. Smith -- IV. Related compulsive and addictive behaviors -- Eating disorders / Mark S. Gold Jodi Star -- Pathologic gambling / Sheila B. Blume and Hermano Tavares -- Addiction and cults: synthesizing a model for treating ex-members / Ron Burks -- Sexual addiction: nosology, diagnosis, etiology, and treatment / Aviel Goodman -- Internet/computer addiction / Zebulon Taintor -- Collecting, accumulation, and hoarding: acquisitions and their discontents / David A. Halperin and Jane Glick -- V. Evaluation and early treatment -- Diagnosis and classification: DSM-IV-TR and ICD-10 / John Cacciola and George E. Woody -- Diagnostic laboratory: screening for drug abuse / Karl G. Verebey, Gerard Meenan, and Betty J. Buchan -- VI. Treatment approaches -- Detoxification / Grace Chang and Thomas R. Kosten -- Alcoholics Anonymous / Edgar P. Nace -- Alternative support groups / Arthur T. Horvath -- The therapeutic community / William B. O'Brien and Fernando B. Perfas -- Methadone maintenance / Joyce H. Lowinson, Ira Marion, Herman Joseph, John Langrod, Edwin A Salsitz, J. Thomas Payte, and Vincent P. Dole -- Buprenorphine for the treatment of opioid addiction / Paul J. Fudala and Charles P. O'Brien -- Alternative pharmacotherapies for opioid addiction / Paul J. Fudala, Robert A. Greenstein, and Charles P. O'Brien -- Individual psychotherapy / Bruce J. Rounsaville, Kathleen M. Carroll, and Sudie Back -- Group therapy with outpatients / Arnold M. Washton -- Family/couples approaches to treatment engagement and therapy / M. Duncan Stanton and Anthony W. Heath -- The role of coercion in drug treatment / Sally L. Satel and David J. Farabee -- Treatment in prisons and jails / Roger H. Peters, Charles O. Matthews, and Joel A. Dvoskin -- Cognitive and behavioral therapies / Lisa M. Najavits, Bruce S. Liese, and Melanie S. Harned -- Network therapy / Marc Galanter -- Acupuncture / Ji-Sheng Han, Alan I. Trachtenberg, and Joyce H. Lowinson -- Faith-based approaches / John G. Langrod, John Muffler, James Abel, James T. Richardson, Eugenia Curet, Herman Joseph, and Pedro Ruiz -- Relapse prevention / Dennis C. Daley and G. Alan Marlatt -- Evaluation and outcome of treatment / Robert L. Hubbard -- VII. Management of associated medical conditions -- Maternal and neonatal effects of alcohol and drugs / Loretta P. Finnegan and Stephen R. Kandall -- Medical complications of drug use / Marc N. Gourevitch and Julia H. Arnsten -- Acute and chronic pain / Russell K. Portenoy, Richard Payne, and Steven D. Passik -- Substance use disorders in individuals with co-occurring psychiatric disorders / Sylvia J. Dennison -- VIII. HIV Infection and AIDS -- Epidemiology and emerging public health perspectives / Don C. Des Jarlais, Holly Hagan, and Samuel R. Friedman -- HIV-related medical complications and treatment / Chinazo O. Cunningham and Peter A. Selwyn -- Neuropsychiatric aspects of HIV- infection / Francisco Fernandez, Jorge Maldonado, and Pedro Ruiz -- Psychosocial issues of HIV/AIDS among drug users in treatment / James L. Sorensen, Nancy A. Haug, and Steven L. Batki -- IX. Life cycle -- Children of substance-abusing parents / Patti Juliana and Carolyn Goodman -- Adolescents / Andres J. Pumariega, Mark D. Kilgus, and Leonardo Rodriguez -- The elderly / Steven R. Gambert and Charles R. Albrecht III -- X. Women's issues -- Alcohol and women / Sheila B. Blume and Monica L. Zilberman -- Drugs and women / Monica L. Zilberman and Sheila B. Blume -- Women's research and policy issues / Marsha Rosenbaum and Sheigla Murphy -- XI. Ethnic populations -- African Americans: epidemiology, prevention, and treatment issues / Charles Madray, Lawrence S. Brown, Jr., and Beny J. Primm -- Hispanic Americans / Pedro Ruiz and John G. Langrod -- Asian Americans and Pacific Islanders / John W. Tsuang -- Alcohol use among American Indians and Alaskan Natives / Edward F. Foulks -- XII. Other populations -- Gays, lesbians, and bisexuals / Robert Paul Cabaj -- The homeless / Herman Joseph and John Langrod -- Disability and rehabilitation issues / Allen W. Heinemann and Purva H. Rawal -- Physicians and other health professionals / G. Douglas Talbott and Philip O. Wilson -- New immigrants and refugees / Joseph Westermeyer -- XIII. Models of prevention -- School-based programs / Gilbert J. Botvin and Kenneth W. Griffin -- Harm reduction: pragmatic drug policies for public health and safety / Ernest Drucker, Ethann Nadelman, Robert G. Newman, Alex Wodak, Jennifer McNeely, Kasia Malinowska-Semprucht, David Marsh, Martin Schechter, Bruna Brands, and Eugene Oscapella -- Church, family, and community in the prevention and treatment of addiction among African Americans / Ronald Hopson and William B. Lawson -- The public health approach to the prevention of substance abuse / Steven Jonas -- XIV. Training and education -- Medical education in substance abuse: the acquisition of knowledge, attitudes, and skills / John N. Chappel -- Education and training of clinical personnel / David A. Deitch, Igor Koutsenok, and Karin Marsolais -- Forensics / Milton Earl Burglass and Stuart Gitlow -- The role of neuropsychological assessment in forensic addiction / Ari D. Kalechstein, Wilfred G. van Gorp, and Garrett J. Zelen -- XV. Policy issues -- A new era for methadone advocacy / Joycelyn Woods, Walter Ginter, and Tony Scro -- The workplace / Paul F. Engelhart and Linda Barlow -- Treatment for alcohol and drug dependence: history, workforce, organization, financing, and emerging policies / Dennis McCarty and Howard H. Goldman -- Legal aspects of confidentiality of patient information / Margaret K. Brooks -- Clinical and societal implications of drug legalization / Herbert D. Kleber and James A. Inciardi -- Index.
  • "Stay up to date with the latest substance abuse treatments and modes of intervention with The Substance Abuse Handbook, 2e. The editors are both nationally recognized clinicians, and provide authoritative, clinically oriented information on the subject of substance use, abuse, and dependence, with an emphasis on diagnosis, treatment, and prevention.You'll find focused, expert information on every aspect of the field, including etiological factors; substances of abuse; compulsive and addictive behaviors; evaluation and diagnostic classification; treatment modalities, management of associated medical conditions; substance abuse in youth and the elderly; women's issue; special groups and settings; models of prevention; training and education; and policy issues. Succinctly presenting the most clinically relevant information from Lowinson and Ruiz's Substance Abuse, 5e, this concise, portable handbook is a must-have reference for anyone involved directly or indirectly in the addiction field.New to This Edition Find the practical information you need fast with this edition's focused coverage of basic science and greater emphasis on clinical concerns. Stay current with the latest information in the field, including changes reflecting the release of DSM-5. Access updated information in key topic areas, including "Special Populations," "Special Settings," and "Models of Prevention."-- Provided by publisher.
  • This book is written for any clinician who encounters substance abuse in a patient and wonders what to do. Experts from a cross-section of specialties and health professions provide up-to-date, evidence-based guidance on how non-expert clinicians can recognize, understand, and approach the management of substance abuse in their patients. They detail the range of treatments available and whether and how they work. The central importance of using a carefully selected multimodal approach that is tailored to the individual patient is emphasized throughout and illustrated in case scenarios from actual clinical practice.
  • The need for college recovery services / Richard P. Wiebe, H. Harrington Cleveland, and Kitty S. Harris -- Collegiate recovery communities : what they are and how they support recovery / Kitty S. Harris, Amanda Baker, and H. Harrington Cleveland -- Facilitating identity development in collegiate recovery : an Eriksonian perspective / Matthew Russell, H. Harrington Cleveland, and Richard P. Wiebe -- Characteristics of collegiate recovery community members / H. Harrington Cleveland, Amanda Baker, and Lukas R. Dean -- Maintaining abstinence in college : temptations and tactics / Richard P. Wiebe, H. Harrington Cleveland, and Lukas R. Dean -- Daily lives of young adult members of a collegiate recovery community / H. Harrington Cleveland and Allison Groenendyk -- How membership in the collegiate recovery community maximizes social support for abstinence and reduces risk of relapse / H. Harrington Cleveland, Richard P. Wiebe, and Jacquelyn D. Wiersma -- Building support for recovery into an academic curriculum : student reflections on the value of staff run seminars / Ann M. Casiraghi and Miriam Mulsow -- Establishing college-based recovery communities : opportunities and challenges encountered / Amanda Baker.
  • Print Material
  • Pt. 1. General principles of substance use disorders -- An initial approach -- Types of use -- The substance use disorders -- Screening techniques -- The first interview -- Outpatient logistics -- Laboratory studies -- Pt. 2. Substance review -- Alcohol -- Other sedatives -- Sedative detoxification -- Medications during sedative recovery -- Nicotine -- Stimulants -- Opiates/opioids -- Opioid detoxification -- Opioid maintenance programs -- Marijuana -- LSD -- Other drugs -- Substance-induced disorders -- Pt. 3. Substance use treatment -- Treatment settings -- Twelve step programs -- Prevention -- Who treats substance use? -- Treatment dilemmas -- Patient placement criteria -- Legal issues -- Spirituality / by Stanley E. Gitlow.
  • Introduction -- Cytology of the subthalamic nucleus -- Ontogeny of the subthalamic nucleus -- Topography of the rat, cat, baboon, and human subthalamic nucleus -- Connections of the subthalamic nucleus -- Nigro-subthalamic connections in rat.
  • Print Material
  • Academic surgeons play an essential role in advancing the field and improving the care of patients with surgical disease. As the Association for Academic Surgery (AAS) Fall Courses ( and international courses continue to evolve to address the rapidly expanding scope and complexity of academic surgery, there is a greater need for an accompanying textbook to supplement the material presented in the courses. Success in Academic Surgery: Basic Science is a unique and portable handbook that focuses on the basic and translational research. It includes new educational materials that are necessary to address not only the rapid evolution and rise of novel research methodologies in basic science and translational research, but also the changing environment for academic surgeons. Success in Academic Surgery: Basic Science is a valuable text for medical students, surgical residents, junior faculty and others considering a career in surgical research.
  • Building Your Clinical Trial Research Team -- Clinical Trials: Ensuring Quality and Standardization -- Statistics: Setting the Stage -- Clinical Trials: Handling the Data -- Data Safety Monitoring Boards -- Planning for Data Monitoring and Audits -- The Budget -- Regulatory Considerations in Human Subjects Research -- Publishing a Clinical Trial -- Device Versus Drug Clinical Trials: Similarities and Important Differences -- Defining the Study Cohort: Inclusion and Exclusion Criteria -- The History of Clinical Trials -- Ethics of Clinical Trials -- Trial Design: Overview of Study Designs (Phase I, II, III, IV, Factorial Design).
  • Success in Academic Surgery: Developing a Career in Surgical Education is a unique and portable handbook that offers careers advice and guidance to medical students, surgical residents, young faculty and others considering a career within surgical education. Surgical education is a rapidly expanding area of surgical research and career interest, and as the Association for Academic Surgery (AAS) fall courses ( and international courses offer more and more specialty tracking there is a greater need for an accompanying textbook to supplement the material presented in the courses. Success in Academic Surgery: Developing a Career in Surgical Education expands on some of the important issues related to surgical education highlighted in the AAS courses by addressing key areas such as how to acquire the skills necessary for success in this field, how to develop a research program in surgical education as well as offering guidance on applying for research grants, among other things.
  • Success in Academic Surgery: Health Services Research is a unique handbook which will help researchers and surgeons in obtaining National Institutes of Health funding and other grants, as well as breaking through the barriers to developing a career in academic surgery. Aimed at surgical residents and young surgical faculty, Success in Academic Surgery: Health Services Research is written by expert authors from around the world who are members of the Association for Academic Surgery, and it offers a practical and personal insight on working in academic surgery.
  • Print Material
    Introduction -- Internal medicine clerkship -- Surgery clerkship -- Pediatrics clerkship -- Psychiatry clerkship -- Obstetrics & gynecology clerkship -- Family medicine clerkship -- Patients -- The new rotation -- Admitting patients -- On call -- Laboratory tests -- Ancillary tests -- Attending rounds -- Oral case presentations -- Write-ups -- The outpatient setting -- Evaluations -- The written exam -- Rotation success -- Attendings -- Working as a team -- Giving talks.
  • Career management / Peggy A. Pritchard -- Continuing professional development / Christine Faerber and Anngienetta Johnson -- Training and working abroad / Mary Osborn -- Climbing the ladder / Ilene J. Busch-Vishniac -- Mentoring / Christine S. Grant -- Networking / Patricia Rankin and Joyce McCarl Nielsen -- Mental toughness / Peggy A. Pritchard -- Personal style / M. Elizabeth Cannon and Kathleen Sendall -- Communicating science / Christine Szymanski -- Time stress / Peggy A. Pritchard -- Balancing professional and personal life / Sarah E. Randolph ... [et al.] -- Transitions / Margaret Ann-Armour and Dorothy Tovell.
  • Targeting oncogenic drivers / Zhao, Y.; Adjei, A.A. (Buffalo, N.Y.) -- Successes and limitations of targeted cancer therapy in breast cancer / Curigliano, G.; Criscitiello, C. (Milan) -- Successes and limitations of targeted cancer therapy in colon cancer / Khne, C.-H. (Oldenburg) -- Successes and limitations of targeted cancer therapy in gastrointestinal stromal tumors / Casali, P.G. (Milano) -- Successes and limitations of targeted cancer therapy in lung cancer / Suda, K. (Osaka-Sayama/Fukuoka); Mitsudomi, T. (Osaka-Sayama) -- Successes and limitations of targeted cancer therapy in melanoma / Romano, R.; Michielin, O. (Lausanne) -- / successes and limitations of targeted cancer therapy in ovarian cancer / Damia, G. (Milan); Sessa, C. (Bellinzona) -- Successes and limitations of targeted therapies in renal cell carcinoma / Pracht, M.; Berthold, D. (Lausanne).
  • Building trust and communication -- Impacts : quality and financial -- Clinical documentation specialist : who is involved and what is the process? -- Clinical documentation specialist and education -- Collaboration with hospital case management -- Putting it all together -- Final thoughts.
  • Why write a grant? -- Becoming familiar with funding sources -- Developing your ideas for funding -- Common sections of proposals -- Strategies for effective writing -- Technical writing considerations -- Developing a budget -- Putting it all together to create a budget -- Technical considerations in budget development -- Four project structures -- Understanding the process of collaboration -- Forming a collaborative team -- Learning about your institution -- Electronic considerations -- Understanding the review process -- Responding to the proposal review -- A case study -- Welcome to the world of post-award -- More post-award considerations.
  • Print Material
    The application -- Specialty-specific information -- The basics -- Selection process -- The right fit -- Curriculum vitae (CV) -- Letters of recommendation -- Personal statement -- Dean's letter (MSPE) -- The audition elective -- The competitive edge -- Before the interview -- Interview questions -- The interview day -- After the interview -- Ranking residency programs -- International medical graduates.
  • Print Material
    Preparing to write -- Composing a first draft -- Visual support for the written word -- Visual support for the spoken word -- Revising to increase coherence -- Improving word choice, and syntax style -- Attending to grammar, numbers, and other mechanics -- The rest of the story.
  • "The authors draw on 50 years of experience, providing detailed step-by-step guidance designed to help students and researchers write and present scientific manuscripts more successfully through knowledge, practice, and an efficient approach."--Publisher description.
  • Why are some societies more successful than others at promoting individual and collective well-being? This book integrates recent research in social epidemiology with broader perspectives in social science to explore why some societies are more successful than others at securing population health. It explores the social roots of health inequalities, arguing that inequalities in health are based not only on economic inequalities, but on the structure of social relations. It develops sophisticated new perspectives on social relations, which emphasize the ways in which cultural frameworks as well as institutions condition people's health. It reports on research into health inequalities in the developed and developing worlds, covering a wide range of national case studies, and into the ways in which social relations condition the effectiveness of public policies aimed at improving health.
  • Medical overview of sudden in-custody deaths / Theodore C. Chan -- The nature of sudden custodial deaths / Darrell L. Ross -- Neck holds / Gary M. Vilke -- Positional and restraint asphyxia / Tom Neuman -- Restraint stress / Elizabeth A. Laposata -- The role of illicit drug use in sudden in-custody death / Aaron B. Schneir and Richard F. Clark -- Excited delirium / Charles V. Wetli -- Riot control agents, taser, and other less lethal weapons / Christian Sloane and Gary M. Vilke -- Case analysis of restraint deaths in law enforcement and corrections / Darrell L. Ross -- Deaths in custody investigations / Vincent Dimiao -- Liability and wrongful custodial deaths / Darrell L. Ross -- Administrative implications / Darrell L. Ross.
  • Sudden infant death syndrome (SIDS) is characterised by the sudden death of an infant that is not predicted by prior medical history and it is still responsible for a large percentage of infant mortalities. The exact causes have long remained unknown, though some risk factors such as including exposure to tobacco smoke, no breast feeding, and prone sleeping position, have been identified. However an analysis linking neurophysiological and neuropathological aspects in a prospective study of SIDS suggests that one of the causes of SIDS is arousal deficiency. This unique book provides the latest, comprehensive information on SIDS research from epidemiology to physiology.
  • The article is a summary of a study that was "part of a larger program of research by The Carnegie Foundation for the Advancement of Teaching on preparation for the professions"--Website.
  • Print Material
    "The goal of this volume is to comprehensively cover a highly readable, updated and extended, overview on our present knowledge of positive and negative effects of UV-exposure, with a focus on vitamin D and skin cancer. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in endocrinology, epidemiology, histology, photobiology, immunology, cytogenetics and molecular pathology to new concepts for prophylaxis and treatment. Experts in the field as well as health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of the second edition of this book to summarize essential up-to-date information for every clinician or scientist interested in how to balance between positive and negative effects of UV-exposure to minimize the risks of developing vitamin D deficiency and skin cancer"--Publisher's description.
  • The SFC market : "yesterday, today, and tomorrow" -- The use of SFC in discovery sciences -- Qualification of SFC hardware and validation of systems -- Method development for achiral SFC -- Achiral preparative supercritical fluid chromatography -- Supercritical fluid chromatography for chiral method development screening and analysis -- Chiral preparative supercritical fluid chromatography -- SFC in process analytical chemistry -- Analytical SFC for impurities -- Supercritical fluid chromatography -- mass spectrometry -- Supercritical fluid chromatography of natural products -- Polarimetric detection in supercritical fluid chromatography -- Supercritical fluid chromatography with ultra-performance particles -- Pilot and production-scale supercritical fluid chromatography.
  • Fundamentals of supercritical fluid technology / Pereda, S., Bottini, S.B. and Brignole, E. -- Supercritical extraction plants / Martinez, J.L. and Vance, S. -- Supercritical fluid extraction of specialty oils / Temelli, F. ... [et al.] -- Extraction and purification of natural tocopherols by supercritical CO / Fang, T. ... [et al.] -- Processing of fish oils by supercritical fluids / Eltringham, W. and Catchpole, O.J. -- Supercritical fluid extraction of active compounds from algae / Mendes, R. -- Application of supercritical fluids in traditional Chinese medicines and natural products / Li, S. -- Extraction of bioactive compounds from Latin American plants / Meireles, M.A. -- Antioxidant extraction by supercritical fluids / Diaz-Reinoso, B. ... [et al.] -- Essential oils extraction and fractionation using supercritical fluids / Reverchon, E. and De Marco, I. -- Processing of spices using supercritical fluids / Mukhopadhyay, M. -- Preparation and processing of micro and nano-scale materials by supercritical fluid technology / Weidner, W. and Petermann, M.
  • MEN1 clinical background / Peter Igaz -- Genetic background of MEN1 : from genetic homogeneity to functional diversity / Patrick Gaudray and Günther Weber -- Menin : the protein behind the MEN1 syndrome / Maria Papaconstantinou ... [et al.] -- Cellular functions of menin / Geoffrey N. Hendy, Hiroshi Kaji and Lucie Canaff -- The role of menin in hematopoiesis / Ivan Maillard and Jay L. Hess -- Role of menin in bone development / Hiroshi Kaji, Lucie Canaff and Geoffrey N. Hendy -- Activin, TGF-€ and menin in pituitary tumorigenesis / Jean-Jacques Lebrun -- The role of menin in parathyroid tumorigenesis / Colin Davenport and Amar Agha -- Role of menin in neuroendocrine tumorigenesis / Terry C. Lairmore and Herbert Chen -- Adrenal tumors in MEN1 syndrome and the role of menin in adrenal tumorigenesis / Attila Patocs, Katalin Balogh and Karoly Racz -- Functional studies of menin through genetic manipulation of the MEN1 homolog in mice / Dheepa Balasubramanian and Peter C. Scacheri.
  • Superoxide distumase 2002
  • PNL is the gold standard for the management of large and/or otherwise complex renal stones. Since its introduction in the seventies PNL has undergone considerable evolution, mainly driven by the improvement in access techniques, endoscopic instrument technology, lithotripsy devices and drainage management. The conventional prone position for PNL has been challenged in the last two decades by a variety of modifications, including the supine and Galdakao-modified supine Valdivia positions, which make simultaneous retrograde working access to the collecting system possible and have proven anesthesiological advantages. The Galdakao-modified supine Valdivia position allowed the development of ECIRS (Endoscopic Combined IntraRenal Surgery), a technique exploiting a combined antegrade and retrograde approach to the upper urinary tract, using both rigid and flexible endoscopes with the related accessories. The synergistic teamwork of ECIRS provides a safe and efficient, minimally-invasive procedure for the treatment of all kinds of urolithiasis. The aim of this book is to share with the urologic community worldwide our experience, our standardization of all the steps, and tips and tricks for the procedure.
  • 1. Febrile neutropenia -- 2. Transfusion support -- 3. Tumor lysis syndrome -- 4. Cardiopulmonary emergencies -- 5. Neurologic emergencies -- 6. Hyperleukocytosis -- 7. The acute abdomen -- 8. Thrombotic disorders -- 9. Pain management -- 10. Nausea and vomiting -- 11. Oral mouth care and mucositis -- 12. Nutrition -- 13. Management of acute radiation side effects -- 14. Prevention of infection -- 15. Hematopoietic growth factors -- 16. Immunization practice in pediatric oncology -- 17. Central venous catheters: care and complications -- 18. Knowledge gaps and opportunities for research.
  • Supportive oncology 2011
    2011 ClinicalKey
  • Natural and induced T CD4+CD25+FOXP3+ regulatory T cells / L. Chatenoud -- Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells / P. Hoffmann, R. Eder and M. Edinger -- Methods for in vitro generation of human type 1 regulatory T cells / S. Gregori, M.G. Roncarolo and R. Bacchetta -- Ex vivo generation of regulatory T cells: Characterization and therapeutic evaluation in a model of chronic colitis / F. Karlsson ... [et al.] -- Phenotypic and functional characterization of CD8(+) T regulatory cells / S. Menoret ... [et al.] -- Regulatory CD4(-)CD8(-) double negative T cells / E.Y. Kim, S.C. Juvet and L. Zhang -- Identifying regulatory B cells (B10 cells) that produce IL-10 in mice / T. Matsushita and T.F. Tedder -- DCs in immune tolerance in steady-state conditions / T. Fukaya ... [et al.] -- Plasmacytoid dendritic cells in tolerance / E. Gehrie ... [et al.] -- In vitro-generated DC with tolerogenic functions: Perspectives for in vivo cellular therapy / C. van Kooten and K.A. Gelderman -- Preparation of mouse bone marrow-derived dendritic cells with immunoregulatory properties / M. Segovia, M.C. Cuturi and M. Hill -- Myeloid-derived suppressor cells: Characterization and expansion in models of endotoxemia and transplantation / N. Van Rompaey and A. Le Moine -- Human regulatory macrophages / J.A. Hutchinson ... [et al.] -- NKT and tolerance / J. Diana ... [et al.] -- Antiinflammatory and immunosuppressive functions of mast cells / J. Kalesnikoff and S.J. Galli -- A mesenchymal stem cell potency assay / J. Jiao ... [et al.] -- In vitro analyses of the immunosuppressive properties of neural stem/progenitor cells using anti-CD3/CD28-activated T cells / V. Bonnamain, I. Neveu and P. Naveilhan -- Immunoregulatory properties of heme oxygenase-1 / P. Blancou ... [et al.] -- Indoleamine 2,3-dioxygenase and regulatory function: Tryptophan starvation and beyond / C. Orabona and U. Grohmann -- Regulatory T cell enrichment by IFN-[gamma] conditioning / G. Feng, K.J. Wood and A. Bushell -- Transforming growth factor-beta: Recent advances on its role in immune tolerance / P.Y. Mantel and C.B. Schmidt-Weber -- Induction of tolerogenic dendritic cells by NF-[kappa]b blockade and fcgamma receptor modulation / L.J. Carreno, C.A. Riedel and A.M. Kalergis -- Fine-tuning antitumor responses through the control of galectin-glycan interactions: An overview / M. Salatino and G.A. Rabinovich -- Regulation of lymphocytes by nitric oxide / C. Bogdan -- Pregnancy: Tolerance and suppression of immune responses / A. Leber ... [et al.] -- Organ transplantation: Modulation of t-cell activation pathways initiated by cell surface receptors to suppress graft rejection / K. Weatherly and M.Y. Braun -- Immunosuppressive mechanisms during viral infectious diseases / G. Sarikonda and M.G. von Herrath -- Ocular immune privilege sites / S. Masli and J.L. Vega -- Immunoprivileged sites: The testis / M. Fijak, S. Bhushan and A. Meinhardt.
  • Print Material
  • Print Material
  • Fulltext Springer
  • Print Material
  • Surgery 2009
    Designed to teach you to think like an experienced clinician, this unique resource places as much value on process as it does on content. A case-based organization hones in on the must-know differential diagnoses of the common surgical presentations. Its convenient pocket-sized format enables you to review the material on the go, and online access via Student Consult enhances your study of the material and exponentially boosts your reference power. Provides high-yield core information essential to surgical rotations in a portable, pocket-sized format.Uses a color-coded system that places the core surgical information in a framework of the ACGME Core Competencies.Offers self-assessment activities throughout to promote retention and application of knowledge, including access on line to your own competency-based portfolio tools and competency-specific learning modules (Vertical Reads).Features ACGME Core Competencies enabling you to integrate evidence based medicine, continual self-assessment, and cognizance of interpersonal skills into your daily routine.Includes features such as "Speaking Intelligently" and "Clinical Thinking" in each chapter to help you see the "big picture."Organizes the most common and must-know surgical signs/symptoms and disorders by presentation, making reference simple.Presents "Teaching Visuals"-an interactive teaching device designed to reinforce visual concepts.Equips you to perform a more in-depth review of surgical topics with "Clinical Entities" that are referenced to top surgical references.
  • Print Material
    Abdominal hernias -- Gallstone disease -- Pancreatitis -- Pancreatic tumours -- Benign breast disease -- Breast cancer -- Goitre -- Thyroid malignancies -- Parathyroid disease -- Pituitary disorders -- Adrenal disorders -- Skin cancer -- Ischaemic heart disease -- Valvular heart disease -- Peripheral occlusive vascular disease -- The diabetic foot -- Aneurysms -- Extracranial arterial disease -- Deep venous thrombosis -- Varicose veins -- Lymphoedema -- Pulmonary collapse and postoperative pneumonia -- Bronchial carcinoma -- Urinary tract infection -- Benign prostatic hypertrophy -- Renal calculi -- Renal cell carcinoma -- Carcinoma of the bladder -- Carcinoma of the prostate -- Testicular cancer -- Urinary incontinence -- Paediatric 'general' surgery -- Solid organ transplantation. Neck lump -- Dysphagia -- Haemoptysis -- Breast lump -- Breast pain -- Nipple discharge -- Haematemesis -- Dyspepsia -- Vomiting -- Acute abdominal pain -- Chronic abdominal pain -- Abdominal swellings (general) -- Abdominal swellings (localized) : upper abdominal -- Abdominal swellings (localized) : lower abdominal -- Jaundice -- Rectal bleeding -- Diarrhoea -- Altered bowel habitconstipation -- Groin swellings -- Claudication -- Acute warm painful leg -- Acute 'cold' leg -- Leg ulceration -- Dysuria -- Urinary retention -- Haematuria -- Scrotal swellings -- Stomas and incisions -- Anaesthesia -- Hypoxia -- Shock -- Systemic inflammatory response syndrome (SIRS) -- Surgical infection -- Acute renal failure -- Fractures -- Burns -- Major trauma - basic principles -- Head injury -- Gastro-oesophageal reflux -- Oesophageal carcinoma -- Peptic ulceration -- Gastric carcinoma -- Malabsorption -- Crohn's disease -- Acute appendicitis -- Diverticular disease -- Ulcerative colitis -- Colorectal carcinoma -- Benign anal and perianal disorders -- Intestinal obstruction --
  • Print Material
  • This book provides an educational resource of modern and advanced operative techniques for patients with GI cancers. The textbook is designed to provide a step-by-step surgical approach, highlighting key learning points and potential operative pitfalls. When appropriate, two or more different approaches on an operative procedure are presented to provide additional perspective on surgical techniques. Written descriptions of laparoscopic and robotic cancer operations are paired with online video presentations of the same cancer operation. Written by experts in the field, Surgery for Cancers of the Gastrointestinal Tract: A Step-by-Step Approach provides a concise summary of the current management of each GI cancer and is of great utility to not only surgeons at all levels of training, but also for surgeons in practice who seek to reinforce or learn new surgical techniques.
  • History of auditory implantation -- Surgical anatomy in auditory implantation -- Radiology in auditory implantation -- Instruments and implants -- Cochlear implantation -- Special considerations in pediatric cochlear implantation -- Complications and revision surgery in cochlear implantation -- Auditory brainstem implantation -- Electroacoustic stimulation -- Subtotal petrosectomy in cochlear implantation -- Cochlear implantation in cochlear ossification -- Meningitis and implantation -- Auditory implantation in otosclerosis patients -- Otomastoiditis and cochlear implantation -- Inner ear malformations and implantation -- Neurofibromatosis type 2 and auditory implantation -- Implantation in skull base and temporal bone lesions -- Bone conduction implants -- Active middle ear implants : vibrant soundbridge.
  • Print Material
  • Anatomy and physiology of velopharyngeal closure and insufficiency / Raol, N., Hartnick, C.J -- Nasometry, videofluoroscopy, and the speech pathologist's evaluation and treatment / de Stadler, M., Hersh, C. -- Nasal endoscopy : new tools and technology for accurate assessment / Raol, N. -- New technology : use of cine MRI for velopharyngeal insufficiency / Raol, N., Sagar, P., Nimkin, K., Hartnick, C.J -- Validated patient-reported outcome instruments for velopharyngeal insufficiency / Skriko, J.R., Sie, K.C.Y. -- Prosthodontics rehabilitation in velopharyngeal insufficiency / Jackson, M. -- Superiorly based pharyngeal flap / Raol, N., Hartnick, C.J. -- Sphincter pharyngoplasty / Raol, N., Hartnick, C.J. -- Furlow double-opposing z-plasty / Raol, N., Hartnick, C.J. -- Posterior pharyngeal wall augmentation / Perez, C.F., Brigger, M.T. -- Persistent velopharyngeal insufficiency / Willging, J.P. -- Obstructive sleep apnea / Willging, J.P.
  • Sleep Disordered Breathing / Kerstin Rohde and Thomas Verse -- General Aspects of Therapy / Thomas Verse -- Identifying the Site of Obstruction / Joachim T. Maurer and Thomas Verse -- Nasal Surgery / Thomas Verse and Wolfgang Pirsig -- Nasopharyngeal Surgery / Thomas Verse and Wolfgang Pirsig -- Palatal Surgery / Thomas Verse, Wolfgang Pirsig and Joachim T. Maurer -- Lower Pharyngeal Airway Procedures / Boris A. Stuck, Thomas Verse, Nico de Vries and Joachim T. Maurer -- Maxillofacial Surgeries / Thomas Verse and Thomas Hierl -- Laryngeal OSA / Thomas Verse -- Multilevel Surgery / Thomas Verse -- Tracheotomy / Thomas Verse and Wolfgang Pirsig -- Bariatric Surgery / Helge Kleinhans and Thomas Verse -- Anesthesiologic Airway Management / Harald V. Genzwuerker.
  • Surgery for the dry eye? / Geerling, G., Brewitt, H. -- The normal tear film / Tiffany, J.M. -- Functional anatomy and immunological interactions of ocular surface and adnexa / Paulsen, F. -- Classification and diagnosis of dry eye / Kaercher, T., Bron, A.J. -- Medical management of the dry eye disease / Tuft, S., Lakhani, S. -- Anti-inflammatory and immunosuppressive concepts / Nölle, B. -- Correction of entropion and ectropiona / Hintschich, C. -- Correction of lid retraction and exophthalmos / Baldeschi, L. -- Lacrimal drainage surgery in a patient with dry eyes / Rose, G.E. -- Surgery of the conjunctiva / Yokoi, N., Inatomi, T., Kinoshita, S. -- Surgery of the cornea : corneal, limbal stem cell, and amniotic membrane transplantation / Kruse, F.E., Cursiefe, C. -- Keratoprosthesis surgery / Liu, C. ... [et al.] -- Eyelid botulinum toxin injections for the dry eye / Sahlin, S., Linderoth, R. -- Plugs for occlusion of the lacrimal drainage system / Tost, F.H.W., Geerling, G. -- Surgical occlusion of the lacrimal drainage system / Geerling, G., Tost, F.H.W. -- Mucous membrane grafting / Henderson, H.W.A., Collin, J.R.O. -- Minor salivary gland transplantation / Geerling, G., Raus, P., Murube, J. Transplantation of the major salivary glands / Geerling, G., Sieg, P. -- Mechanical pump dacryoreservoirs / Murube, J., Geerling, G. -- Clinical trials in dry eye in surgery for dry eye? / Lemp, M.A. -- Animal models of dry eye / Schrader, S., Mircheff, A.K., Geerling, G. -- Flow chart on surgical approaches to dry eye / Geerling, G., Brewitt, H.
  • Filling a significant knowledge gap, this book brings the latest information to the evaluation and treatment of patients with a dysfunctional sacroiliac (SI) joint. Beginning with an overview of current anatomical knowledge and the role of pain and surgery, diagnosis and treatment approaches are carefully presented as individual chapters - featuring the origin of each surgical approach, the approach itself, its literary foundation, and overall available results. The final emphasis of the book is on post-operative concerns - including complications, bracing options, rehabilitation and managing patient expectations. Spine surgeons, physical therapists, and other professionals who treat the SI joint will find Surgery for the Painful, Dysfunctional Sacroiliac Joint to be an invaluable resource.
  • Etiology and epidemiology of urinary incontinence / W. Stuart Reynolds -- Preoperative evaluation of patients with urinary incontinence and selection of appropriate surgical procedures for stress incontinence / W. Stuart Reynolds Mickey Karram -- Surgical anatomy of the anterior vaginal wall, retropubic space, and inner groin / Mickey Karram -- Retropubic operations for stress urinary incontinence / Mark D. Walters -- Biologic bladder neck pubovaginal slings / Mickey Karram, Dani Zoorob, and W. Stuart Reynolds -- Retropubic synthetic midurethral slings / Mickey Karram, Dani Zoorob, and W. Stuart Reynolds -- Transobturator synthetic midurethral slings / Dani Zoorob and Mickey Karram -- Single incision minislings / Mickey Karram, W. Stuart Reynolds, and Dani Zoorob -- Surgical management of voiding dysfunction and retention after stress incontinence surgery / Mickey Karram -- Bulk enhancing agents for stress incontinence : indications and techniques / Roger Dmochowski -- Sacral neuromodulation / W. Stuart Reynolds and Roger Dmochowski -- Botulinum toxin injection therapy / W. Stuart Reynolds and Roger Dmochowski -- Bladder augmentation / W. Stuart Reynolds and Roger Dmochowski -- Mixed and recurrent incontinence, incontinence in patients with pelvic organ prolapse, and how best to avoid and manage complications; case discussions / Mickey Karram, W. Stuart Reynolds, and Roger Dmochowski.
  • Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.
  • History of cerebellopontine angle surgery -- Microsurgical anatomy of the cerebellopontine angle by the retrosigmoid approach -- Neuropathology of the cerebellopontine angle and its surroundings -- Approaches to the cerebellopontine angle -- Vestibular schwannomas -- Neurofibromatosis Type 2 and other bilateral cerebellopontine angle tumors -- Meningiomas -- Cerebellopontine angle epidermoids -- Nonvestibular schwannomas -- Jugular foramen tumors -- Other cerebellopontine angle tumors -- Management of facial palsy.
  • Section I: Brachial plexus injury and entrapments -- Brachial plexus avulsion--diagnostic issues / Thomas Kretschmer and Robert L. Tiel -- Upper brachial plexus injury (duchenne-erb palsy) / Andrew C. Kam and Daniel H. Kim -- Lower trunk brachial plexus palsy / Lynda J-S. Yang and John E. McGillicuddy -- Gunshot wounds to the brachial plexus / Robert J. Spinner and Robert L. Tiel -- Lateral cord injury / Robert L. Tiel and Eric L. Zager -- Medial cord injury / Robert J. Spinner and Robert L. Tiel -- Pediatric plexus injuries / James M. Drake, Patrick A. Lo, and Rajiv Midha -- Secondary reconstruction in obstetric brachial plexus injuries / Rahul K. Nath ... [et al.] -- Free functioning muscle transfers for upper extremity reconstruction of plexus palsy / Dimitri J. Anastakis and Ralph T. Manktelow -- Dorsal root entry zone: lesioning for intractable deafferentation pain / Mahmood Fazl ... [et al.] -- Neurotization in brachial plexus injury / Rahul K. Nath ... [et al.] -- Thoracic outlet syndrome / Eric L. Zager -- Nerve transfers for shoulder reanimation / Bassam M. J. Addas and Rajiv Midha -- Fascicular nerve transfers to restore elbow flexion / Ronald T. Grondin, S. Durand, and Christophe Oberlin -- Section II: Upper extremity peripheral nerve injuries and entrapments -- Spinal accessory nerve palsy / Robert L. Tiel and Eric L. Zager -- Long thoracic nerve palsy / Adrian W. Laxton and Rajiv Midha -- Suprascapular nerve palsy / Adrian W. Laxton and Rajiv Midha -- Axillary nerve injury and repair / Deb Bhowmick and Eric L. Zager -- Injury to the median nerve above the elbow / Ben Roitberg -- Anterior interosseous nerve syndrome/compression / Allen H. Maniker -- Carpal tunnel syndrome / Sheila K. Singh and Rajiv Midha -- Endoscopic carpal tunnel release / David F. Jimenez and Thomas Loftus -- Recurrent or persistent symptoms following carpal tunnel release / Brent Graham -- Digital nerve injuries / Paul Binhammer -- Ulnar nerve injury / Marie-Noëlle Hébert-Blouin and Line Jacques -- Failed ulnar nerve transposition due to unrecognized snapping of the medial triceps / Robert J. Spinner and Rajiv Midha -- Ulnar nerve entrapment at the elbow / Farhad Pirouzmand and Rajiv Midha -- Ulnar nerve compression--guyon canal / Christopher Doumas and David R. Steinberg -- Failed ulnar nerve decompression / James B. Lowe III and Susan E. Mackinnon -- Management of penetrating (lacerating) nerve injuries / Mandeep S. Tamber and Rajiv Midha -- Radial nerve injury: midhumeral level / Mubarak Al-Gahtany and Rajiv Midha -- Radial tunnel syndrome / Farhad Pirouzmand and Rajiv Midha -- Posterior interosseous nerve injury / Andrew Nataraj and Rajiv Midha -- Nerve repair with conduits / Matthew Sanborn, Eric M. Jackson, and Eric L. Zager -- Section III: Lower extremity peripheral nerve injuries and entrapments -- Ilioinguinal/iliohypogastric neuropathy / R. Graham Vanderlinden and Rajiv Midha -- Meralgia paresthetica / Douglas Cook and Rajiv Midha -- Obturator nerve injury and repair / Jason H. Huang, Robert G. Whitmore, and Eric L. Zager -- Femoral neuropathy by compression from iliacus compartment hematoma / Farhad Pirouzmand and Rajiv Midha -- Femoral nerve injuries / Allen H. Maniker -- Saphenous nerve lesions / Robert J. Spinner and Robert L. Tiel -- Sciatic nerve compression and piriformis syndrome / Robert J. Spinner and Robert L. Tiel -- Sciatic nerve injury and repair / Robert G. Whitmore, Deb Bhowmick, and Eric L. Zager -- Diagnosis and treatment of common peroneal nerve problems / Tarvinder Singh and Michel Kliot -- Peroneal nerve entrapment / Kimberly Harbaugh and Rajiv Midha -- Sural nerve injury and neuroma / Rajiv Midha -- Posterior tibial nerve injury / Justin L. Owen ... [et al.] -- Tarsal tunnel syndrome / Robert J. Spinner and Robert L. Tiel -- Morton neuroma / Neal J. Naff -- Section IV: Nerve tumors, painful nerve conditions, and miscellaneous injuries -- Schwannoma / W. Bradley Jacobs and Rajiv Midha -- Neurofibroma / W. Bradley Jacobs and Rajiv Midha -- Management of malignant peripheral nerve sheath tumors / Nabeel Al-Shafai, Rajiv Midha, and Abhijit Guha -- Brachial plexus tumor / Mubarak Al-Gahtany and Rajiv Midha -- Neurogenic sarcoma of the sciatic nerve / Charles Christian Matouk and Rajiv Miidha -- Lumbar plexus injury / Eric M. Jackson and Eric L. Zager -- Complex regional pain syndrome / Raqeeb Haque and Christopher J. Winfree -- Upper dorsal sympathectomy for hyperhidrosis / Mahmood Fazl -- Electrical stimulation for painful neuroma / Michael J. Dorsi and Allan J. Belzberg.
  • Print Material
  • This book addresses shoulder instability--all comers because the extreme variability of patients and pathology must be matched with a variety of techniques.
  • History -- Anatomy -- Intramedullary tumors -- Extramedullary tumors -- Epidural tumors.
  • Historical Background or De quibusdam Renum glandulis: The History of Adrenals / Donatella Lippi -- Surgical Anatomy / Celestino Pio Lombardi, Carmela De Crea, Francesco Pennestri and Marco Raffaelli -- Pathology / Gabriella Nesi and Raffaella Santi -- Diagnosis and Clinical Pictures / Gabriele Parenti and Massimo Mannelli -- Imaging / Massimo Falchini and Vittoria Rufini -- Perioperative Management / Tommaso Borracci, Luca Vitali, Lorenzo Antonuzzo, Liliana Sollazzi and Valter Perilli, et al. -- General Principles of Adrenal Surgery / Robin M. Cisco and Quan-Yang Duh -- Instrumentation and High-Technology / Francesco Corcione, Valentina Brancato and Michele Giuseppe Iovino -- Right Flank Trans-Abdominal Laparoscopic Adrenalectomy / Carlo Bergamini and Andrea Valeri -- Left Flank Trans-Abdominal Laparoscopic Adrenalectomy / Celestino Pio Lombardi, Marco Raffaelli, Carmela De Crea, Francesco Pennestri and Rocco Bellantone -- Posterior Retroperitoneoscopic Adrenalectomy / Rocco Bellantone, Marco Raffaelli, Carmela De Crea, Luigi Oragano and Celestino Pio Lombardi -- Open Adrenalectomy / Giorgio De Toma, Andrea Polistena and Giuseppe Cavallaro -- Other Techniques of Video-Assisted and Open Adrenalectomies / Rocco Bellantone, Francesco Corcione, Celestino Pio Lombardi, Marco Raffaelli and Carmela De Crea, et al. -- Outcome of Adrenal Surgery / Andrea Valeri and Carlo Bergamini.
  • Print Material
    v.1. The Esophagus -- v. 2. Stomach and duodenum, incisions, sutures -- v. 3. Colon, anorectal tract -- v. 4. Pancreas, biliary tract, liver, spleen -- v. 5. Mesentery vasculature; hernias; small intestine; peritoneum, omentum, mesentery and retroperitoneum; surgical nutrition.
  • Print Material
    v. 1. General consideratons and intracapsular cataract extraction / by J. Barraquer, J. Rutllán ; with the cooperation of R.C. Troutman -- v. 2. Surgery of the cornea.
  • This book gives comprehensive coverage of common and rare colorectal conditions, advances in the molecular biology and genetics of colorectal diseases, new laparoscopic techniques, and more. Contributions from international experts on specialized topics and 400 new illustrations ensure that the extensive text is not only current and authoritative, but easy to understand.
  • Section I. Foundations for Surgical Treatment -- Section II. Surgical Indications and Decision Making -- Section III. Surgical Techniques -- Section IV Fixation and Fusion Techniques.
  • Print Material
  • Print Material
  • Surgery of the hip 2013
    Surgery of the Hip is your definitive, comprehensive reference for hip surgery, offering coverage of state-of-the-art procedures for both adults and children. Modelled after Insall & Scott Surgery of the Knee, it presents detailed guidance on the latest approaches and techniques, so you can offer your patients - both young and old - the best possible outcomes.
  • Print Material
  • Surgery of the knee 2014
    The knee presents numerous challenges to the orthopaedic surgeon and this book presents techniques and guidance both for common surgical procedures and also for rare and difficult interventions in knee surgery. Surgical techniques and approaches in knee surgery are covered as well as postoperative complications and rehabilitation. Chapters also discuss clinical examination and preparation of the patient prior to the procedure. Surgery of the Knee is a comprehensive step-by-step guide that features more than 500 operative photographs, radiological and surgical drawings of exceptional quality. The Editors have brought together a team of experts within the field ensuring that orthopaedic surgeons in training and those wishing to improve their knowledge of the knee will find this book to be an indispensable resource for performing knee surgery.
  • Print Material
    Surgical and radiologic anatomy of the liver, biliary tract, and pancreas -- Assessment of liver function in the surgical patient -- Liver blood flow: physiology, measurement, and clinical relevance -- Liver regeneration -- Liver hyperplasia, hypertrophy, and atrophy -- Bile secretion -- Biliary tract pathophysiology -- Pancreatic physiology and functional assessment -- Endotoxin and cytokines in liver and biliary tract disease -- Infections in hepatic, biliary, and pancreatic surgery -- Genetics and molecular biology of pancreatic and biliary cancers -- Molecular biology of liver carcinogenesis and hepatitis -- Liver immunology -- Clinical investigation of hepatopancreatobiliary disease -- Ultrasound of the liver, biliary tract, and pancreas -- Endoscopic ultrasound -- The role of nuclear medicine in the diagnosis and management of hepatobiliary and pancreatic diseases -- Computed tomography of the liver, biliary tract, and pancreas -- Magnetic resonance imaging of the liver, biliary tract, and pancreas -- Direct cholangiography -- Angiography -- Percutaneous biopsy -- Intraoperative diagnosis of liver, biliary, and pancreatic disease -- Preoperative and postoperative nutrition in hepatobiliary surgery -- Anesthesia and postoperative intensive care -- Perioperative critical care in hepatobiliary surgery -- Quality of life and hepatobiliary tumors -- Interventional endoscopy: technical aspects -- Radiologic hepatobiliary interventions -- Biliary-enteric anastomosis -- The natural history of gallstones and asymptomatic gallstones -- Cholecystitis -- Percutaneous approaches to the treatment of gallbladder disease -- The technique of cholecystectomy -- Laparoscopic cholecystectomy and choledocholithotomy -- Stones in the common bile duct-clinical features and open surgical approaches and techniques -- Stones in the bile duct: endoscopic and percutaneous approaches -- Cholecystolithiasis and stones in the common bile duct: which approach, when? -- Postcholecystectomy problems -- Intrahepatic stones -- Biliary atresia -- Primary sclerosing cholangitis -- Biliary stricture and fistula -- Definition and classification of pancreatitis -- Etiology, pathogenesis, and diagnostic assessment of acute pancreatitis -- Management of acute pancreatitis and complications -- Etiology, pathogenesis, and diagnosis of chronic pancreatitis -- Management of chronic pancreatitis: conservative, endoscopic, and surgical -- Tumors of the bile ducts-pathologic aspects -- Benign tumors and pseudotumors of the biliary tract -- Tumors of the gallbladder -- Intrahepatic and extrahepatic biliary cancer -- Pathology and classification of pancreatic and ampullary tumors -- Periampullary and pancreatic tumors -- Palliation of pancreatic and periampullary tumors -- Pancreaticoduodenectomy, distal pancreatectomy, segmental pancreatectomy, total pancreatectomy, and transduodenal resection of the papilla of vater -- Endocrine tumors of the pancreas: clinical picture, diagnosis, and therapy -- Cholangitis -- Pyogenic liver abscess -- Amebiasis and other parasitic infections -- Hydatid cyst of the liver -- Recurrent pyogenic cholangitis -- Bile duct cysts in adults -- Nonparasitic cystic diseases of the liver and intrahepatic biliary tree -- Surgical management of cystic disease of the liver -- Liver, biliary, and pancreatic injury -- Aneurysm and arteriovenous fistula of the liver and pancreatic vasculature -- Hemobilia and bilhemia -- Tumors of the liver-pathologic aspects -- Benign liver lesions -- Hepatocellular carcinoma -- Hepatic tumors in childhood -- Metastatic tumors -- Embolization of liver tumors -- Radiotherapy of liver tumors -- Ablation of liver tumors -- Chemotherapy of liver tumors -- Isolated hepatic perfusion for extensive liver cancers -- Intra-arterial chemotherapy for liver tumors -- Liver resection for benign disease and for liver and biliary tumors -- Vascular isolation techniques in liver resection -- Liver resection in cirrhosis of the liver -- Segment-oriented anatomic liver resections -- Portal vein embolization -- Ex vivo and in situ hypothermic hepatic resection -- Intraoperative ultrasound of the liver: techniques for liver resection and transplantation -- Cirrhosis and portal hypertension: pathologic aspects -- Management of liver failure -- Support of the failing liver -- Management of ascites in cirrhosis and portal hypertension -- Medical management of bleeding varices -- Endoscopic therapy in the management of esophageal varices: injection sclerotherapy and variceal ligation -- Portal hypertension in children -- Operative devascularization and esophageal transection -- The place of portosystemic shunting -- The place of transjugular intrahepatic portosystemic shunting -- The technique of portacaval shunt -- Distal splenorenal shunt -- The mesocaval shunt: technique -- Budd-chiari syndrome and veno-occlusive disease -- Liver and pancreatic transplantation immunobiology -- Liver transplantation: anesthesia, perioperative management, and postoperative intensive care -- Liver transplantation: indications -- Orthotopic liver transplantation -- Liver transplantation in patients with fulminant hepatitis -- Liver transplantation for tumors -- Liver transplantation in children and segmental transplantation -- Auxiliary liver transplantation -- Living donor liver transplantation -- Early and late complications of liver transplantation -- Techniques of liver replacement -- Whole organ pancreas and pancreatic islet transplantation.
  • Surgery of the pediatric spine 2008
    Thieme eNeurosurgery
    This book is a comprehensive multidisciplinary reference for the surgical management of the most frequently encountered spine problems in the pediatric patient. An overview of developmental and clinical aspects provides essential information on biomechanics, neuroimaging, preoperative evaluation, anesthesia, and neurophysiological monitoring. The book goes on to present the surgical anatomy and various approaches to the spine and spinal cord. Chapters are grouped into easy-to-reference sections that are organized by type of problem, including congenital anomalies and developmental disorders; neoplasms; vascular malformations; inflammatory and infectious diseases; neuromuscular disease; trauma; and deformities. The book also presents special techniques for the treatment of spinal deformity, such as osteotomy, vertebrectomy, VEPTR expansion thoracoplasty, and fusionless techniques. A chapter devoted to the rehabilitation of children with spinal cord injury covers the principles and key concepts in treatment, as well as the possible secondary complications and challenges that are unique to pediatric patients.
  • Anatomy for procedural dermatology / June K. Robinson -- Aseptic technique / Christie R. Travelute and Todd V. Cartee -- Anesthesia and analgesia / Teresa T. Soriano, Andrew Breithaupt, and Cameron Chesnut -- Instruments and materials / William Lear -- Patient evaluation, informed consent, preoperative assessment, and care / Mara C. Weinstein and Allison T. Vidimos -- Antibiotics / Kavita Mariwalla -- Wound healing / Sonia Lamel, Jie Li, and Robert S. Kirsner -- Wound healing and its impact on dressings and posoperative care / Yakir Levin, Katherine L. Brown, and Tania J. Phillips -- Electrosurgery / Diana Bolotin and Murad Alam -- Cryosurgery / Paola Pasquali -- Skin biopsy techniques / Andrew G. Affleck and Graham Colver -- Incision, draining, and exteriorization techniques / Masato Yasuta -- Suturing technique and other closure materials / Divya Srivastava and R. Stan Taylor -- Complex layered facial closures / Edgar F. Fincher, Hayes B. Gladstone, and Ronald L. Moy -- Hemostasis / Pedro Redondo -- Ellipse, ellipse variations, and dog-ear repairs / Allison Hanlon, Samuel E. Book, and David J. Leffell -- Random pattern cutaneous flaps / Jonathan L. Cook, Glenn D. Goldman, and Todd E. Holmes -- Axial pattern flaps / Christopher J. Miller, Tri Nguyen, and Joseph F. Sobanko -- Skin grafting / Alvaro E. Acosta ... [and 4 others] -- Acne scar revision / Greg J. Goodman -- Revision of surgical scars / Justin J. Leitenberger ... [and 3 others] -- Psychosocial issues and the cosmetic surgery patient / Dee Anna Glaser -- Evaluation and management of the aging face / Lisa M. Donofrio -- Soft-tissue augmentation / C. William Hanke ... [and 4 others] -- Chemical peels / Marina Landau and Sahar F. Ghannam -- Implants / J. Michael Carney -- Botulinum toxins / Doris Hexsel and Camile L. Hexsel -- Liposuction / C. William Hanke ... [and 4 others] -- Autologous fat transfer : evolving concepts and techniques / Kimberly J. Butterwick -- Follicular unit hair transplantation / Robert M. Bernstein -- Laser hair removal / William G. Stebbins ... [and 3 others] -- Laser treatment of tattoos and pigmented lesions / Rachel N. Pritzker ... [and 3 others] -- Photodynamic therapy / Anne Goldsberry ... [and 3 others] -- Laser-based treatment of the aging face for skin resurfacing : ablative and non-ablative lasers / Omar A. Ibrahimi, Nazanin Saedi, and Suzanne L. Kilmer -- Laser and light treatment of acquired and congenital vascular lesions / Johnny Chun Yin Chan and Henry Hin Lee Chan -- Sclerotherapy of varicose veins / Eberhard Rabe, Franz X. Breu, and Felizitas Pannier -- Endovenous thermal ablation techniques with ambulatory phlebectomy for varicose veins / Sanja Schuller-Petrović, Felizitas Pannier, and Milos̆ D. Pavlović -- Lamellar high-SMAS minimum incision face lift / Robert C. Langdon -- Vertical vector face lift with local anesthesia / Rafael A. Schulze, Brian Somoano, and Greg S. Morganroth -- Blepharoplasty and brow-lift / Alina Fratila and young Kyoon Kim -- Rejuvenation of the neck using liposuction and other techniques / William G. Stebbins, Michael S. Kaminer, and C. William Hanke -- Rejuvenation of the external female genitalia / Doris Hexsel, Sebastian Pop, and Antonio Rusciani -- Keloid management / Brian Berman, Sadegh Amini, and Hilary Baldwin -- Vitiligo surgery / Niti Khunger, Koushik Lahiri, and Venkataram Mysore -- Mohs micrographic surgery and cutaneous oncology / Hubert T. Greenway ... [and 4 others] -- Leg ulcer management / Ysabel Bello... [and 3 others] -- Nail surgery / Eckart Haneke -- Repair of the split earlobe, ear piercing, and earlobe reduction / Sirunya Silapunt and Leonard H. Goldberg -- Hidradenitis suppurativa / Virginia J. Reeder, David Ozog, and Iltefat Hamzavi -- Assessment and treatment of photoaging-related mottled pigmentation / Se Young Na and Kyoung Chan Park -- Design of the surgical suite, including large equipment, and monitoring devices / Ross M. Levy and C. William Hanke -- Dermatology office accreditation / Ross M. Levy. Emily Tierney, and C. William Hanke.
  • Comprehensive surgical textbook on the diagnosis and management of benign and malignant disease of the thyroid and parathyroid glands.
  • Print Material
  • Surgery on the move 2014
  • Print Material
  • Print Material
    Pre and postoperative care -- Critical care : anesthesiology, blood gases, and respiratory care -- Skin : wounds, infections, and burns : hands : plastic surgery -- Trauma and shock -- Transplants, immunology, and oncology -- Endocrine problems and the breast -- Gastrointestinal tract, liver, and pancreas -- Cardiothoracic problems -- Peripheral vascular problems -- Urology -- Orthopedics -- Neurosurgery -- Otolaryngology -- Pediatric surgery.
  • Surgery review illustrated 2005
    AccessSurgery, Users must register and sign in to take a test
  • Print Material
  • "The Fifth Edition of Greenfield's Surgery has been thoroughly revised, updated, and refocused to conform to changes in surgical education and practice. Reflecting the increasingly clinical emphasis of residency programs, this edition features expanded coverage of clinical material and increased use of clinical algorithms. Key Points open each chapter, and icons in the text indicate where Key Points are fully discussed. Many of the black-and-white images from the previous edition have been replaced by full-color images"--Provided by publisher.
  • Surgery: A Case Based Clinical Review provides the reader with a comprehensive understanding of surgical diseases in one easy-to-use reference that combines multiple teaching formats. The book begins using a case based approach. The cases presented cover the diseases most commonly encountered on a surgical rotation. The cases are followed by a series of short questions and answers, designed to provide further understanding of the important aspects of the history, physical examination, differential diagnosis, diagnostic work-up and management, and questions that may arise on surgical rounds. Key figures and tables visually reinforce the important elements of the disease process. Surgery: A Case Based Clinical Review will be of great utility for medical students when they rotate on surgery, interns, physician assistant students, nursing students, and nurse practitioner students.
  • Surgery: An Introductory Guide is an all-in-one reference that provides the vital information needed to get the best learning experience out of an operation, and presents it in a convenient, efficient, and portable format. Each section brings together the key points from several different fields including anatomy, pathophysiology, radiology, surgical technique, and clinical guidelines. The operations covered represent the breadth of general surgery including hernia repair, cholecystectomy, breast surgery, general bowel surgery, and vascular surgery. Each chapter provides informative text, bulleted lists, and common OR questions, combined with classic radiology images, diagrams, and a color illustration of the operative anatomy. This method of using key words, high-yield diagrams, and illustrations enhances the ability to quickly absorb and retain the relevant information. The volume is also organized by operation rather than by pathological topic, which lends itself to quick review before each case. Written by Dr. Sarpel, a surgeon and former co-clerkship director who has been honored with multiple teaching awards, Surgery: An Introductory Guide is of great value to medical students and junior residents rotating on general surgery.
  • Surgery-- PreTest self-assessment and review. 13th ed. 2012
    AccessSurgery, Users must register and sign in to take a test
    Pre- and postoperative care -- Critical care : anesthesiology, blood gases, and respiratory care -- Skin : wounds, infections, and burns : hands : plastic surgery -- Trauma and shock -- Transplants, immunology, and oncology -- Endocrine problems and the breast -- Gastrointestinal tract, liver, and pancreas -- Cardiothoracic problems -- Peripheral vascular problems -- Urology -- Orthopedics -- Neurosurgery -- Otolaryngology -- Pediatric surgery.
  • Print Material
  • Featuring an expanded focus on in-demand endoscopic and minimally invasive spine procedures, Surgical Anatomy and Techniques to the Spine, 2nd Edition pairs new anatomic photographs and radiographic images with expertly rendered color illustrations and clear, step-by-step descriptions to help you effectively perform all of the latest and most effective spine surgery techniques. A multidisciplinary approach makes this medical reference book relevant and informative to all surgeons regardless of their specialty or level of surgical experience with the spine. Proceed with confidence. An atlas-style format featuring clear, concise, step-by-step descriptions of the anatomy and procedures along with clinical hints and pearls, tables, and management algorithms provideing swift answers and trusted guidance.Sharpen your surgical acumen with a deeper understanding of the anatomy of the surgical target and related anatomy. Comprehensive information on cervical, cervical/thoracic, thoracic/lumbar, lumbar spine, lumbar/pelvis, and other surgical locations ensures the best approaches to spine surgery and results.Understand the spine from all angles with multiple-viewpoint, full-color photographs, and illustrations.
  • Generations of residents and general surgeons have relied upon and worn out their copies of Surgical Anatomy and Technique: A Pocket Manual. Thoroughly revised and with dozens of new illustrations, the fourth edition continues the tradition of providing a concise, accessible, and generously illustrated memory refresher for both novice and experienced clinicians. The editors have included techniques to keep the content fresh, relevant, and practice-based. Among the new topics are hand surgery, a section on central venous access, and creating an AV fistula for dialysis. All the existing chapters have been updated and expanded to reflect current surgical approaches and instrumentation. This fourth edition of Surgical Anatomy and Technique: A Pocket Manual provides the gold standard in correlating clear, practical anatomy with the correct technique in the pursuit of the best possible patient outcomes. This handy pocket manual remains a "must have" for every resident and general surgeon.
  • Print Material
  • This atlas provides all the basic and advanced information required by surgeons in order to understand fully the skull base anatomy. It is organized according to anatomo-surgical pathways to the hidden areas of the skull base. These pathways are described in step-by-step fashion with the aid of a wealth of color images and illustrations. The emphasis is on endoscopic anatomy, but in order to provide a holistic perspective, informative three-dimensional reconstructions are presented alongside the endoscopic images and radiologic images are included when appropriate. In effect, windows are opened
  • Physics : include medical precautions -- Instrumentation -- Advanced technologies : 3D ultrasound, contrast ultrasound -- Ultrasound of the neck, thyroid and parathyroid -- Breast ultrasound -- Abdominal ultrasound : principles (transabdominal, intraoperative, laparoscopic) -- Hepatobiliary ultrasound : include rf and other ablative therapies -- Ultrasound of pancreas -- FAST : trauma ultrasound -- Critical care ultrasound : includes chest ultrasound -- Endoscopic ultrasound : foregut including esophagus, stomach, small intestine, biliary -- Endoscopic ultrasound : hindgut including endorectal -- Genitourinary ultrasound -- Vascular ultrasound -- Ultrasound-guided regional anesthesia -- Therapeutic ultrasound -- Documentation, coding, billing, and compliance -- Credentialing.
  • Print Material
  • Cardiac Anatomy: Nomenclature and Abbreviations -- Position and Observation of the Heart and Surgical Approaches -- The Right Atrium -- The Right Ventricle -- The Coronary Artery -- The Conduction System of the Heart -- The Left Atrium -- The Left Ventricle -- The Cardiac Skeleton and the Aortic Root -- General Considerations of Cardiac Embryology -- Atrial Septal Defect and Cor Triatriatum -- Atrioventricular Septal Defect -- Ventricular Septal Defect -- Anomalous Pulmonary Venous Drainage -- Aortic Arch Coarctation and Interrupted Aortic Arch -- Congenital Anomalies of the Tricuspid Valve -- Right Ventricular Outflow Tract Obstruction -- Mitral Atresia and Hypoplastic Left Ventricle -- Single Ventricle -- Persistent Truncus Arteriosus -- Aortopulmonary Window -- Aneurism of the Sinus of Valsalva -- Tetralogy of Fallot -- Double Outlet Right Ventricle -- Complete Transposition of the Great Arteries -- Corrected Transposition of the Great Arteries -- Pulmonary Atresia -- Double-outlet of Left Ventricle.
  • A brief history of perforator flaps -- Anatomy, classification and nomenclature -- Intra-operative techniques in perforator dissection -- Pedicled perforator flaps -- Combined perforator flaps -- Thinned perforator flaps -- Flow-through perforator flaps -- Lateral Arm Perforator Flap -- Medial arm perforator flap -- Radial Artery Perforator Flap -- Ulnar Artery Perforator Flap -- posterior interosseous artery perforator flap -- Posterolateral mid-forearm perforator flap -- Dorsal Metacarpal Artery Perforator Flaps -- Dorso-ulnar metacarpal perforator flap of the little finger -- Digital artery perforator flap -- Perforator flaps in the lateral thoracic region -- Deep inferior epigastric artery perforator (DIEP) flap -- Anterolateral thigh perforator flap -- Vastus medialis perforator flap -- Saphenous artery perforator flap -- Posterior thigh perforator flap -- Anterior tibial artery perforator flap -- Posterior tibial artery perforator flap -- Peroneal artery perforator flap -- Medial sural artery perforator flap -- Peroneal artery anterolateral supramalleolar flap -- Anterior supramalleolar perforator flap -- Medial supramalleolar perforator flap -- Dorsal metatarsal artery perforator flap.
  • This atlas depicts and describes the newest arthroscopic and open techniques for dealing with sports orthopaedic injuries and problems. More than 75 surgical procedures are presented step by step with the aid of superb illustrations. Arthroscopic views, artist drawings, X-rays, and clinical and operative photographs are all included to demonstrate exactly how each procedure should be performed. Individual sections are devoted to the shoulder, elbow, pelvis/hip, knee, and ankle/foot. By offering complete illustrated guidance on the surgical management of sports-related injuries, the Surgical Atlas of Sports Orthopaedics and Sports Traumatology will prove invaluable to both novice and experienced surgeons.
  • Print Material
  • Front Matter -- Supplemental Images -- Surgical Critical Care. Respiratory and Cardiovascular Physiology / Marcin A Jankowski, Frederick Giberson -- Cardiopulmonary Resuscitation, Oxygen Delivery, and Shock / Timothy J Harrison, Mark Cipolle -- Arrhythmias, Acute Coronary Syndromes, and Hypertensive Emergencies / Harrison T Pitcher, Timothy J Harrison -- Sepsis and the Inflammatory Response to Injury / Juan C Duchesne, Marquinn D Duke -- Hemodynamic and Respiratory Monitoring / Christopher S Nelson, Jeffrey P Coughenour, Stephen L Barnes -- Airway Management, Anesthesia, and Perioperative Management / Jeffrey P Coughenour, Stephen L Barnes -- Acute Respiratory Failure and Mechanical Ventilation / Lewis J Kaplan, Adrian A Maung -- Infectious Disease / Charles Kung Chao Hu, Heather Dolman, Patrick McGann -- Pharmacology and Antibiotics / Michelle Strong -- Transfusion, Hemostasis and Coagulation / Stacy Shackelford, Kenji Inaba -- Analgesia and Sedation / Juan C Duchesne, Marquinn D Duke -- Delirium, Alcohol Withdrawal, and Psychiatric Disorders / Meghan Edwards, Ali Salim -- Acid-Base, Fluid and Electrolytes / Charles Kung Chao Hu, Andre Nguyen, Nicholas Thiessen -- Metabolic Illness and Endocrinopathies / Therese M Duane, Andrew Young -- Hypothermia and Hyperthermia / Raquel M Forsythe -- Acute Kidney Injury / Terence O'keeffe -- Liver Failure / Bellal Joseph -- Nutrition / Rifat Latifi -- Neurocritical Care / Scott H Norwood, Herb A Phelan -- Venous Thromboembolism / Herb A Phelan, Scott H Norwood -- Transplantation, Immunology, and Cell Biology / Leslie Kobayashi -- Obstetric Critical Care / Gerard J Fulda, Anthony Sciscione -- Envenomations, Poisonings and Toxicology / Michelle Strong -- Common Procedures in the ICU / Adam D Fox, Daniel N Holena -- Diagnostic Imaging, Ultrasound, and Interventional Radiology / Randall S Friese, Terence O'Keeffe -- Emergency Surgery. Neurotrauma / Bellal Joseph -- Blunt and Penetrating Neck Trauma / Leslie Kobayashi -- Cardiothoracic and Thoracic Vascular Injury / Leslie Kobayashi -- Abdominal and Abdominal Vascular Injury / Leslie Kobayashi -- Orthopedic and Hand Trauma / Brett D Crist, Gregory J Della Rocca -- Peripheral Vascular Trauma / Daniel N Holena, Adam D Fox -- Urologic Trauma / Hoylan Fernandez, Scott Petersen -- Care of the Pregnant Trauma Patient / Julie L Wynne, Terence O'Keeffe -- Esophagus, Stomach, and Duodenum / Andrew Tang -- Small Intestine, Appendix, and Colorectal / Jay J Doucet, Vishal Bansal -- Gallbladder and Pancreas / Andrew Tang -- Liver and Spleen / Narong Kulvatunyou -- Incarcerated Hernias / Narong Kulvatunyou -- Soft-Tissue and Necrotizing Infection / Joseph J DuBose -- Obesity and Bariatric Surgery / Stacy A Brethauer, Carlos V R Brown -- Burns, Inhalation Injury, Electrical and Lightning Injuries / Joseph J DuBose -- Urologic and Gynecologic Surgery / Julie L Wynne -- Cardiovascular and Thoracic Surgery / Jared L Antevil, Carlos V R Brown -- Extremes of Age: Pediatric Surgery and Geriatrics / Michael C Madigan, Gary T Marshall -- Telemedicine and Surgical Technology / Rifat Latifi -- Statistics / Randall S Friese -- Ethics, End-of-Life, and Organ Retrieval / Lewis J Kaplan, Felix Lui -- Index.
  • With the introduction of new post-graduate Medical training in the UK, virtually all doctors will be exposed to some form of surgical training prior to specialization. Many of these doctors will have little exposure to surgical emergencies in medical school. Thus, they may unnecessarily refer to a senior doctor when not needed, or catastrophically neglect a patient needing urgent surgical opinion. Surgical Emergencies in Clinical Practice is a compact resource which allows any clinician, without previous surgical knowledge, to be able to make an accurate diagnosis and have a treatment plan for the whole spectrum of surgical emergencies. The essential steps of initial management of all surgical emergencies is outlined in a manner that can be used on a day-to-day basis for clinical management. Written by experts in the field, Surgical Emergencies in Clinical Practice is a valuable tool for all junior doctors and medical students in the UK, Europe, Asia and North America. It will also be of interest to nurse practitioners, general practitioners and allied health professionals managing these patients.
  • Part I. The thyroid gland -- Thyroid physiology -- Emil Theodor Kocher -- Karl von Basedow -- Jan Wolff and Israel L. Chaikoff -- Hyperthyroidism and thyroiditis -- Robert James Graves -- Henry Stanley Plummer -- Hakaru Hashimoto -- Fritz de Quervain -- George W. Crile -- Multinodular goiter -- Hugh Spear Pemberton -- Medullary thyroid carcinoma -- John Richard Farndon -- Well-differentiated thyroid cancer: papillary, follicular, and oncocytic (Hürthle) cell cancer -- Karl Hürthle -- Update of the treatment guidelines for well-differentiated thyroid cancer -- Frank Lahey -- Thomas Dunhill -- Part II. The parathyroid glands -- Primary hyperparathyroidism: diagnosis and workup -- Sir Richard Owen -- Fuller Albright -- James Bertram Collip -- Surgical management of hyperparathyroidism -- Felix Mandl -- Oliver Cope -- Parathyroidectomy: postoperative considerations/complications -- Frantis̆ek Chvostek -- Armand Trousseau -- Theodor Billroth -- Part III. The adrenal glands -- Adrenal physiology -- Thomas Addison -- Primary aldosteronism -- Jerome W. Conn -- Cushing's Syndrome -- Harvey Cushing -- J. Aidan Carney -- Pheochromocytoma and paraganglioma -- Charles Horace Mayo -- Arthur M. Shipley -- Emil Zuckerkandl -- Part IV. Neuroendocrine tumors of the pancreas -- Part IV. Neuroendocrine tumors of the pancreas -- Insulinomas -- Sir Fredrick Grant Banting -- Charles Herbert Best -- Allen Oldfather Whipple -- William J. Mayo -- Gastrinoma -- Robert Milton Zollinger -- Edwin H. Ellison -- VIPoma -- John V. Verner Jr. and Ashton B. Morrison -- Glucagonoma -- Small bowel neuroendocrine tumors -- Carcinoid syndrome -- Sigfried Oberndorfer -- Part V. Hereditary endocrine syndromes -- von Hippel-Lindau Disease -- Eugen von Hippel and Arvid Lindau -- Multiple endocrine neoplasia type 1 -- Paul Wermer -- Norman W. Thompson -- Multiple endocrine neoplasia 2 syndromes -- John H. Sipple -- Index.
  • "Few medical fields have enjoyed the explosive growth and continued maturation as the subspecialty of endovascular surgical neuroradiology. In pouring through the literature on all things associated with neurointerventional, I recognized the need to develop a resource that brought focus to the many devices and the techniques and procedures we do. This book does just that: It brings to sharp focus the most current, and up-to-date methods of an ever-changing specialty. It brings this information to you, through the lens of experts in their respective fields by focusing all their research into the textbook that sits before you. The "Clinical Practice" portion of this textbook integrates and translates this theory into a working paradigm that brings benefit to our patients. By focusing on technique and emphasizing complication avoidance and in those unfortunate times when the complication occurs, complication management, your patient benefits"--Provided by publisher.
  • Surgical English 2010
    Methodological Approach to Surgical English -- Surgical Grammar -- Scientific Literature: Writing an Article -- Letters to Editors of Surgical Journals -- Attending an International Surgical Course -- Presenting an Oral Communication in English -- Chairing a Surgical Session -- Typical Mistakes That Surgeons Make When Speaking and Writing in English -- Latin and Greek Terminology -- Acronyms and Abbreviations in Surgery and Medicine -- Glossary of Surgical Terms -- Surgical English by Surgical Specialty -- Taking a Clinical History -- Writing a Surgical Report, Describing a Surgical Technique, Dictating a Report -- Writing a Hospital Discharge Report -- How to Write a Letter Requesting a Visit -- How to Write an International Curriculum Vitae -- Surgical Instruments -- Managing a Surgical Department -- Surgical Conversation Guide -- Conversation Survival Guide -- A Few Words About Effective Communication.
  • The shoulder -- The humerus -- The elbow -- The forearm -- The wrist and hand -- The spine -- Pelvis and acetabulum -- The hip -- The femur -- The knee -- The tibia and fibula -- The ankle and foot -- Approaches for external fixation.
  • Presents coverage that encompasses anatomy and physiology, and evaluation of breast discussions of breast cancer risk and management of breast cancer... equipping you to confidently face any challenge. Addresses hot topics including gynecomastia, neoadjuvant therapy, management of ductal carcinoma in situ, Paget's disease, risk assessment and genetic testing, breast MRI, partial breast irradiation, microarray analysis, and targeted therapies...providing you with a current perspective of this fact changing field. Begins each chapter with a bulleted list of key points, and presents crucial facts in boxes, to help facilitate review. Features abundant illustrations, photographs, and tables that clarify complex concepts. Follows a concise, logical, and consistent organization that makes the material easy to review. Whether studying for the boards or reviewing key material in preparation for a procedure.
  • There is a revolution in new glaucoma surgical techniques. New glaucoma surgical devices are taking precedence in glaucoma surgery, with the new surgeries drastically cutting down on the chances for patient infection as well as higher success rates compared to the older types of surgery. Surgical Innovations in Glaucoma is the only book of its kind written by the top experts in the field, from inventors, clinical trial investigators, and top specialists experienced with the new devices. Written for general ophthalmologists who perform glaucoma surgery, the text walks the reader through the what, where, when, and how of the new glaucoma surgical tools, and includes supplementary online how-to videos for those interested in seeing the latest glaucoma procedures performed with these devices.
  • Supplemental oxygen therapy -- Airway management in the intensive care unit -- Vascular cannulation -- Fluid resuscitation -- Vasoactive amines and inotropic agents -- Shock -- Hemodynamic monitoring -- Acid-base disorders -- Analgesia and sedation -- Neuromuscular blocking agents -- Optimization of the high-risk surgical patient -- Cardiopulmonary resuscitation -- Management of closed head injury -- Spinal cord injuries -- Ischemic stroke -- Hemorrhagic stroke -- Status epilepticus -- Critical illness plyneuorpathy and myopathy -- Management of hypertension in the perioperative period -- Postoperative myocardial infarction -- Management of postoperative arrhythmias -- Acute respiratory failure -- Mechanical ventilation -- Venous thromboembolism -- Fat emulsion syndrome -- Venous air embolism -- Sepsis -- Vascular catherter-related bloodstream infections -- Pneumonia -- Intra-abdominal sepsis -- Evaluation of the febrile patient in the ICU -- Antimicrobial use in surgical intensive care -- Coagulation abnormalities in the critically ill -- Blood products -- Hyperglycemia in the surgical intensive care unit -- Adrenal insufficiency -- Nutrition support in intensive care -- Acute kidney injury -- Renal replacement therapy -- Disorders of electrolytes -- Gastrointestinal bleeding -- Acute pancreatitis -- Trauma -- Burns -- The abdominal compartment syndrome -- Rhabdomyolysis -- Postoperative care of the cardiac surgical patient -- Postoperative care following major vascular surgery -- Postoperative care after bariatric surgery -- Care of the organ donor -- Postoperative care of the heart transplant patient -- Postoperative care of the lung-transplant patient -- Postoperative care of the liver-transplant patient -- Postoperative care of the pancreas-transplant recipient -- Management of the critically ill geriatric patient -- Alcohol withdrawal in the surgical patient: prevention and treatment -- Ethics and the end-of-life care -- Scoring systems and outcome prediction -- Improving the intensive care unit -- Continuing education in critical care medicine.
  • Surgical Management of Benign Esophageal Disorders: The ""Chicago Approach"" covers all stages of the diagnosis and treatment of the most common benign esophageal disorders in a concise and easy-to-read format. Indications, patient preparation, operative techniques, and strategies for avoiding and managing complications are included and based both on evidence-based data and the experience of the most famous esophageal surgeons in the United States and abroad. Each chapter includes a summary of the current management strategy for the disease process, and a review of current state of the art techniques provided by world leaders on esophageal disease, surgeons and gastroenterologists alike.
  • Microsurgical principles for anterior circulation aneurysms -- Treatment of ruptured cerebral aneurysms: clip and coil, not clip versus coil -- Distal anterior cerebral artery aneurysms -- Treatment of complex intracranial aneurysms of anterior circulation using multiple clips -- Overview of spontaneous cervicocephalic arterial dissection in Japan -- Incidence of intracranial arterial dissection in non-emergency outpatients complaining of headache: preliminary investigation with MRI/MRA examinations -- A study of vertebrobasilar artery dissection with subarachnoid hemorrhage -- Surgical treatment of intracranial VA dissecting aneurysm -- Management of spontaneous dissection of the cervical carotid artery -- Natural history of arteriovenous malformations: presentation, risk of hemorrhage and mortality -- Present state of microneurosurgery of cerebral arteriovenous malformations -- Management of dural arteriovenous fistulas: Helsinki and Kuopio experience -- The rationale behind "a randomized trial of unruptured brain AVMs" (ARUBA) -- Posterior circulation EC-IC bypass via supracerebellar transtentorial SCTT approach applied in a young patient with congenital multiple occlusive cerebrovascular anomalies: case report and technical note -- Superficial temporal artery-to-middle cerebral artery anastomosis with encephalo-duro-myo-synangiosis as a modified operative procedure for moyamoya disease -- Long-term results of carotid endarterectomy and carotid stenting -- Application of microscope integrated indocyanine green video-angiography during microneurosurgical treatment of intracranial aneurysms: a review -- Principles of neuroanesthesia in stroke surgery -- Prevention of symptomatic vasospasm by continuous cisternal irrigation with mock-CSF containing ascorbic acid and Mg2+.
  • 1. Complete Transposition of the Great Arteries 2. Corrected Transposition of the Great Arteries -- 3. Left Ventricular Outflow Tract Anomalies -- 4. Tetralogy of Fallot -- 5. Ebstein's Anomaly.
  • Recent advances in cardiac allotransplantation / John Adams Jarcho and James C. Fang -- Surgical revascularization in the management of heart failure and ischemic left ventricular dysfunction / Jeffrey J. Teuteberg and James C. Fang -- Aortic valve surgery with severe left ventricular dysfunction / Blasé A. Carabello -- Mitral valve surgery with severe left ventricular dysfunction / Vinay Badhwar and Steven F. Bolling -- Tricuspid valve surgery in right heart failure / James P. Greelish ... [et al.] -- Pacing in heart failure / Uday N. Kumar, Teresa De Marco, and Leslie A. Saxon -- Left ventricular assist devices / Paul L. DiGiorgi, Yoshifumi Naka, and Mehmet C. Oz -- Left ventricular volume reduction surgery for idiopathic dilated cardiomyopathy / Richard Lee ... [et al.] -- Surgical management of hypertrophic cardiomyopathy / William G. Williams ... [et al.] -- Dynamic cardiomyoplasty and new prosthetic LV girdling devices / Michael A. Acker -- Xenotransplantation / Joren C. Madsen and Ruediger Hoerbelt -- Left ventricular reconstruction for ischemic heart failure / Vincent Dor -- The total artificial heart in the surgical management of congestive heart failure / Jack G. Copeland, Francisco A. Arabia, and Richard G. Smith.
  • Injectable intraocular corticosteroids / Paul A. Kurz ... [et al.] -- Intraocular corticosteroid implants / David Callanan -- Noncorticosteroid intraocular drug therapy / Francine Behar-Cohen, Jean-Louis Bourges -- Therapeutic vitrectomy for noninfectious uveitis / Kathrin Greiner, Andrew D. Dick -- Cryotherapy and laser for intermediate uveitis / Javier A. Montero, Jose M. Ruiz-Moreno -- Surgery for band keratopathy / Ruth Lapid-Gortzak ... [et al.] -- Selection of surgical technique for complicated cataract in uveitis / Mauricio Miranda, Jorge L. Alió -- Perioperative medical management / Manfred Zierhut, Peter Szurman -- Pars plana lensectomy / Emilio Dodds -- Extracellular extraction by phacoemulsification / Antoine P. Brézin, Dominique Monnet -- Selection of intraocular lenses : materials, contraindications, secondary implants / Gerd U. Auffarth -- Management of posterior synechiae, peripheral anterior synechiae, iridocorneal adhesions, and iridectomy / Yosuf El-Shabrawi -- Complications post cataract surgery in the uveitic eye / Marie-José Tassignon, Dimitrios Sakellaris -- Cataract surgery in childhood uveitis / Arnd Heiligenhaus, Carsten Heinz, Bahram Bodaghi -- Surgical management of uveitis-induced angle-closure glaucoma / Kaweh Mansouri, Tarek Shaarawy -- Surgical management of open-angle glaucoma associated with uveitis / Herbert P. Fechter, Richard K. Parrish II -- Cyclodestructive procedures / Torsten Schlote -- Macular surgery for posterior segment complications of uveitis / Janet L. Davis -- Surgical treatment of retinal vasculitis with occlusion, neovascularization or traction / Jose M. Ruiz-Moreno, Javier A. Montero -- Surgical treatment of uveitic commplications : retinal detachment / Heinrich Heimann -- Surgical management of ocular hypotony / Mark Hammer, W. Sanderson Grizzard -- Anterior chamber tap and aqueous humor analysis / Uwe Pleyer, Justus G. Garweg -- Surgery for the diagnosis of uveitis-anterior segment biopsy / Bahram Bodaghi -- Diagnostic vitrectomy / Christoph M.E. Deuter, Sabine Biester, Karl Ulrich Bartz-Schmidt -- Choroidal biopsy / Christoph M.E. Deuter, Sabine Biester, Karl Ulrich Bartz-Schmidt -- Retinal biopsy / Janet L. Davis.
  • Surgical Management of Pain, Second Edition, is a completely updated state-of-the-art reference on neurosurgical pain management. This new edition is in full color and includes the following sections: Anatomic and Physiologic Foundations for Nociceptive and Neuropathic Pain, Pain Medicine, Pain Diagnoses, Surgical Procedures for Pain, and New Directions for Pain Surgery. The chapters in the book focus on procedures that are currently performed by neurosurgeons to relieve pain. Key Features: Emphasizes best evidence treatment options free online access to videos demonstrating surgical technique.
  • Epidemiology, risk factors, and social impact of pelvic organ prolapse / Corina Schmid and Christopher F. Maher -- Surgical anatomy of the pelvis and the anatomy of pelvic support / Mickey Karram -- Preoperative evaluation and staging of patients with pelvic organ prolapse / Mickey Karram -- Indications and techniques for vaginal hysterectomy and vaginal trachelectomy in patients with pelvic organ prolapse / Mickey Karram -- Surgical procedures to suspend a prolapsed uterus / Christopher F. Maher and Mickey Karram -- Robot-assisted laparoscopic colpo- and cervicosacropexy with the da Vinci Surgical System / Catherine A. Matthews -- Surgical management of apical vaginal prolapse / Christopher Maher and Mickey Karram -- Surgical management of anterior vaginal wall prolapse / Christopher F. Maher and Mickey Karram -- Surgical correction of posterior pelvic floor defects / Mickey Karram -- Obliterative procedures for pelvic organ prolapse / Janelle Evans and Mickey Karram -- Surgery for pelvic organ prolapse : avoiding and managing complications / Mickey Karram and Christopher F. Maher.
  • Print Material
    Pathogenesis of acute spinal cord injury and theoretical bases of neurological recovery / Arun Paul Amar -- Pharmacotherapy for spinal cord injury / Steven Casha, Joseph Silvaggio, R. John Hurlbert -- Prehospital and emergency department management of spinal cord injury / Stuart P. Swadron, Danny L. Chang, Brian Wilbur -- Radiographic workup of spinal cord injury / Nestor R. Gonzalez, Larry T. Khoo, Richard G. Fessler -- Controversies in surgical decompression : timing of decompressive surgery of the spinal cord / Mark S. Gerber, Volker K.H. Sonntag -- Biomechanics of spinal column failure / Eric P. Roger, G. Alexander Jones, Edward C. Benzel -- Principles of spine stabilization / G. Alexander Jones, Eric P. Roger, Edward C. Benzel -- Controversies in the management of cervical spinal cord injury / Paul G. Matz, Mark N. Hadley -- Surgical decision-making in spinal fracture dislocations / Robert G. Watkins -- Spinal cord injury in pediatric patients / Philipp R. Aldana, Douglas L. Brockmeyer -- Management of penetrating spinal cord injury / K. Anthony Kim, Arun Paul Amar, Michael L. Levy -- Traumatic vascular injury to the cervical spine / Michael L. DiLuna, Arun Paul Amar -- Intraoperative neurophysiologic monitoring during spinal surgery / Indro Chakrabarti, Jerry Larson, Gordon L. Engler, Steven L. Giannotta -- Surgery after the acute phase of traumatic spinal cord injury / Michael Y. Wang, Barth A. Green.
  • A who's who in this challenging field brings you state-of-the-art approaches to the full range of surgical management options, including reconstructive procedures, for the pediatric and adult patient with spinal deformity. Experts discuss the course of treatment for patients in different age groups and take into consideration the extent of the curve at the time of diagnosis and during follow-up, the patient's stage of bone growth, the amount of pain and deformity associated with the condition, and the patient's willingness and ability to withstand surgery. Plus, a section on general information such as practical surgical anatomy, imaging, applied biomechanics, and instrumentation helps you approach each patient more effectively. The included DVD helps you perfect your technique with narrated surgical procedures. Emphasizes technical skills and surgical decision making, including pearls, pitfalls, and illustrative case studies, offering you expert advice on technically challenging surgeries. Provides the very latest information on minimally invasive endoscopic and mini-open approaches to broaden your surgical options and minimize post-operative complications. Discusses peri-operative considerations, including anesthesia, blood loss management, bone graft and fusion enhancement, neural monitoring, and complications, keeping you prepared for any event. Presents full-color line artwork of surgical procedures as well as diagnostic and clinical photographs for superb visual guidance. Offers a consistent format throughout and a full-color design for ease of reference. Website includes a video library of narrated surgical procedures to help you master your technique.
  • What is mentoring and who is a mentor? -- Why surgical mentoring is important and evidence that it makes a difference -- What are the qualities of an outstanding surgical mentor? -- How and where should surgical mentoring be performed? -- Mentoring women surgeons -- Mentoring international medical graduates -- How to develop faculty mentors -- How to choose a mentor -- Future directions.
  • This volume is a comprehensive, state-of-the-art review for clinicians with an interest in the peri-operative nutritionalmanagement of all surgical patients. The text reviews normal physiology, the pathophysiology of starvation and surgical stressors, and focuses on appropriate nutritional repletion for various common disease states. Specifically, the text addresses the severe metabolic demands created by systemic inflammation, infection, and major insults such as trauma and burns. In addition, the book addresses the growing problem of obesity in surgical populations, including appropriate strategies directed towards the metabolic management of these patients. The text is designed for clinicians across levels of training and provides clear and concise evidence based guidelines for the metabolic management and nutritional support of the surgical patient. Written by experts in the field, Surgical Metabolism: The Metabolic Care of the Surgical Patient is a valuable resource forall cliniciansinvolved in the care of the critically ill.
  • Print Material
    v. 1. Functional anatomy of craniofacial arteries -- v. 2. Endovascular treatment of craniofacial lesions -- v. 3. Functional vascular anatomy of brain, spinal cord and spine -- v. 4. Endovascular treatment of cerebral lesions -- v. 5. Endovascular treatment of spine and spinal cord lesions.
  • This volume provides a comprehensive perspective on surgical oncologic diseases that are relevant to those who have an interest in surgical oncology. Its purpose is to distill a voluminous amount of information to readers so they will have the opportunity to apply relevant information and knowledge to their particular needs. Each chapter is written by experts in their field who provide concise and in-depth information on their topic and supply references to key articles. Illustrations, diagrams, and photographs are included to assist the visual learners. Each chapter begins with bulleted key points to focus the readers on the material that will be covered and concludes with an appendix that summarizes the salient points. This unique set-up can be used as a tool to quickly review the topic at hand. The text also includes a set of short questions and answers at the end of each chapter to reinforce the salient points. Surgical Oncology: A Practical and Comprehensive Approach is a valuable resource for Medical students, surgical oncology fellows, general surgeons, and educators.
  • Imaging of endocrine and neuroendocrine tumors -- Fine needle aspiration cytology of endocrine tumors -- Fine needle aspiration cytology of neuroendocrine tumors arising in non-endocrine organs -- Tumors of the pituitary gland -- Tumors of thyroid gland : non-C cell tumors -- Tumors of the thyroid gland (C-cells) -- Tumors of parathyroid gland -- Tumors of the adrenal cortex -- Tumors of the adrenal medulla and extra-adrenal paraganglia -- Endocrine tumors of the lung and upper airways -- Neuroendocrine tumors of the pancreas -- Neuroendocrine tumors of the gastrointestinal tract -- Neuroendocrine tumours of the breast -- Neuroendocrine tumors of female genital tract -- Neuroendocrine tumors of prostate, urinary bladder, and kidney -- Neuroendocrine tumors of other miscellaneous sites : thymus and skin -- Endocrine tumors and tumor-like lesions of infancy, childhood, and adolescents and inherited tumor syndromes -- Application of molecular diagnosis techniques in the diagnosis and management of endocrine tumors.
  • Pseudotumors -- Benign Vascular Tumors -- Benign Mesenchymal Tumors and Miscellaneous Tumors -- Benign Hepatocellular Tumors -- Benign Biliary Tumors -- Hepatocellular Carcinoma Precursor Lesions -- Hepatocellular Carcinoma -- Fibrolamellar Carcinoma -- Cholangiocarcinoma Precancerous Lesions -- Cholangiocarcinoma -- Malignant Mesenchymal Tumors -- Hematolymphoid Lesions -- Benign Pediatric Hepatic Tumors -- Malignant Pediatric Liver Tumors -- Metastatic Tumors. .
  • Print Material
    1. Introduction -- 2. Surgical Syndromes -- 3. Surgical Most Commons -- 4. Surgical Percentages -- 5. Surgical History -- 6. Surgical Instruments -- 7. Sutures and Stitches -- 8. Surgical Knot Tying -- 9. Procedures for the Surgical Ward and Clinic -- 10. Incisions -- 11. Surgical Positions -- 12. Surgical Speak -- 13. Preoperative 101 -- 14. Surgical Operations You Should Know -- 15. Wounds -- 16. Drains and Tubes -- 17. Surgical Anatomy Pearls -- 18. Fluids and Electrolytes -- 19. Blood and Blood Products -- 20. Surgical Hemostasis -- 21. Common Surgical Medications -- 22. Complications -- 23. Common Causes of Ward Emergencies -- 24. Surgical Respiratory Care -- 25. Surgical Nutrition -- 26. Shock -- 27. Surgical Infection -- 28. Fever -- 29. Surgical Prophylaxis -- 30. Surgical Radiology -- 31. Anesthesia -- 32. Surgical Ulcers -- 33. Surgical Oncology -- 34. GI Hormones and Physiology -- 35. Acute Abdomen and Referred Pain -- 36. Hernias -- 37. Laparoscopy -- 38. Trauma -- 39. Burns -- 40. Upper GI Bleeding -- 41. Stomach -- 42. Bariatric Surgery -- 43. Ostomies -- 44. Small Intestine -- 45. Appendix -- 46. Carcinoid Tumors -- 47. Fistulas -- 48. Colon and Rectum -- 49. Anus -- 50. Lower GI Bleeding -- 51. Inflammatory Bowel Disease: Crohn's Disease and Ulcerative Colitis -- 52. Liver -- 53. Portal Hypertension -- 54. Biliary Tract -- 55. Pancreas -- 56. Breast -- 57. Endocrine -- 58. Thyroid Gland -- 59. Parathyroid -- 60. Spleen and Splenectomy -- 61. Surgically Correctable HTN -- 62. Soft Tissue Sarcomas and Lymphomas -- 63. Skin Lesions -- 64. Melanoma -- 65. Surgical Intensive Care -- 66. Vascular Surgery -- 67. Pediatric Surgery -- 68. Plastic Surgery -- 69. Hand Surgery -- 70. Otolaryngology: Head and Neck Surgery -- 71. Thoracic Surgery -- 72. Cardiovascular Surgery -- 73. Transplant Surgery -- 74. Orthopaedic Surgery -- 75. Neurosurgery -- 76. Urology.
  • Print Material
  • This volume provides a comprehensive review and detailed description of surgical techniques for prostate cancer surgery. All aspects are covered, including surgical anatomy and methods of transrectal ultrasound guided prostate biopsies, step-by-step approach techniques for radical prostatectomy, and the latest data on outcomes. Furthermore, limitations as well as tips and tricks are detailed in addition to management of common complications. Lastly, with the increasing use of ablative therapy and brachytherapy, the mechanism of action as well as the keys to obtaining optimal outcomes are illustrated. Surgical Techniques for Prostate Cancer is a concise and valuable resource to surgeons that documents the different approaches to prostate cancer surgery.
  • Surgical Techniques of the Shoulder, Elbow, and Knee in Sports Medicine presents you with a step-by-step approach on performing both open and arthroscopic surgeries for sports-related injuries. This medical reference book offers all of the expert guidance you need on everything from patient positioning and the latest orthopaedic surgery techniques, through pearls and pitfalls and post-operative care. An international group of contributors equips you with a worldwide perspective on the most recent orthopaedic advances, making Surgical Techniques of the Shoulder, Elbow, and Knee in Sports Medicine your go-to digest of today's common procedures. Ensure optimal outcomes from each shoulder, elbow and knee procedure with this orthopaedic surgery text's consistent, step-by-step approach, coupled with numerous tips, pearls, pitfalls, and images gleaned from surgeons specializing in sports injuries. Apply the latest open and arthroscopic techniques, including arthroscopic rotator cuff repair and hamstring and allograft ACL reconstruction. Access the full text and expanded surgical video collection online at Expert Consult.
  • Epidemiology and Natural History -- Diagnosis and Staging -- Evolution of Resectability Criteria -- Surgical Strategy -- Results of Surgery and Prognostic Factors -- Preoperation Chemotherapy -- Synchronous Colorectal Liver Metastases -- Therapeutic Strategies in Unresectable Colorectal Liver Metastases -- Extrahepatic Disease -- Adjuvant Chemotherapy and Follow-Up -- LiverMetSurvey Registry: the Italian Experience.
  • Introduction -- History -- Basic Anatomy and Physiology -- Prenatal Diagnosis -- Neo-Natal Management -- Colostomy -- Imaging -- Bowel Preparation -- Perineal Fistula -- Bulbar Fistula -- Prostatic Fistula -- Bladder Neck Fistula -- No Fistula -- Minimally Invasive Approach -- Re-Operations on Male Patients -- Vestibular Fistula -- Cloacas -- Cloacal Exstrophy -- Bowel Management -- Operations to Administer Enemas -- Urologic Problems -- Hirschsprung{u2019}s Disease -- Idiopathic Constipation -- Perianal Fistula -- Posterior Sagittal Approach for Other Conditions -- Rare, Complex Defects -- Associated Defects in General -- Future, Advances -- Long Term Follow-Up -- Sacrococcygeal Teratoms -- ARM in Developing Countries -- Hemorrhoids -- Polyps -- Angiodysplasia Gastro Rectal Heterotopia Rectal Bleeding.
  • A reference that addresses the challenging issues you face in this rapidly growing segment of orthopaedic practice. Inside, youll find top surgical management strategies for all types of hip arthroplasty presented by leaders from around the world, along with discussions of possible complications, risks and benefits to specific patient populations, and more. A DVD, included with the text, presents step-by-step narrated videos of the surgeries covered in the book, enabling you to see these procedures in action.
  • Print Material
    1. Isotropic phenomena in biogeochemistry / M.D. Kamen -- 2. The biogeochemistry of vanadium / D. Bertrand -- 3. The biogeochemistry of vertebrate excretion / G.E. Hutchinson.
  • Print Material
  • Overview / Cindy L. Schwartz ... [et al.] -- Algorithms of late effects by disease / Cindy L. Schwartz, Wendy L. Hobbie, Louis S. constine -- Facilitating assessment of late effects by organ system / Cindy L. Schwartz, Wendy L. Hobbie, Louis S. Constine -- Central nervous system effects / Nina S. Kadan-Lottick, Joseph P. Neglia -- Neuroendocrine complications of cancer therapy / Wing Leung, Susan R. Rose, Thomas E. Merchant -- Ocular complications due to cancer treatment / Michael Ober, Camille A. Servodidio, David Abramson -- Head and neck / Arnold C. Paulino, Mary Koshy, Della Howell -- Adverse effects of cancer treatment on hearing / Wendy Landier, Thomas E. Merchant -- The thyroid gland / Tithi Biswas, Louis S. constine, Cindy L. Schwartz -- Cardiovascular effects of cancer therapy / M. Jacob Adams ... [et al.] -- Pulmonary effects of antineoplastic therapy / Andrea S. Hinkle, Cindy Proukou, Yuhchyau Chen -- Late gastrointestinal and hepatic effects / M.M. Hudson -- The ovary / Debra L. Friedman -- The testes / Jill P. Ginsberg, Amit Maity -- Genitourinary / Lawrence Marks, Nicole Larrier -- Musculoskeletal, integument, breast / Robert B. Marcus, Jr. ... [et al.] -- Hematopoietic stem cell transplantation / Nancy Bunin, constance DiDomenico, Virginia Guzikowski -- Second malignancies following treatment for childhood cancer / Barbara Anne Hieb, Susan K. Ogle, Anna T. Meadows -- Psychological aspects of long-term survivorship / Mary T. Rourke, Anne E. Kazak -- Legal issues / Barbara Hoffman -- Methodological issues in the study of survivors of childhood cancer / Ann C. Mertens, Yutaka Yasui -- Transition issues / Kevin C. Oeffinger, Debra A. Eshelman.
  • "The second WHO report builds on the growing sense of optimism generated by the 2012 publication of the WHO roadmap. Commitments on the part of ministries of health in endemic countries, global health initiatives, funding agencies and philanthropists have escalated since 2010, as have donations of medicines from pharmaceutical companies and the engagement of the scientific community. This report marks a new phase and assesses opportunities and obstacles in the control, elimination and eradication of several of these diseases. Unprecedented progress over the past two years has revealed unprecedented needs for refinements in control strategies, and new technical tools and protocols. The substantial increases in donations of medicines made since the previous report call for innovations that simplify and refine delivery strategies. However, some diseases, including especially deadly ones like human African trypanosomiasis and visceral Leishmaniasis, remain extremely difficult and costly to treat. The control of Buruli ulcer, Chagas disease and yaws is hampered by imperfect technical tools, although recent developments for yaws look promising. The report highlights progress against these especially challenging diseases, being made through the development of innovative and intensive management strategies. innovations in vector control deserve more attention as playing a key part in reducing transmission and disease burden, especially for dengue, Chagas disease and the Leishmaniases. Achieving universal health coverage with essential health interventions for neglected tropical diseases will be a powerful equalizer that abolishes distinctions between the rich and the poor, the young and the old, ethnic groups, and women and men."--P. 4 of cover.
  • This edited volume addresses a rising concern among natural resource scientists and management professionals about decline of the many plant and animal species associated with early-successional habitats, especially within the Central Hardwood Region of the USA. These open habitats, with herbaceous, shrub, or young forest cover, are disappearing as abandoned farmland, pastures, and cleared forest patches return to forest. There are many questions about 'why, what, where, and how' to manage for early successional habitats. In this book, expert scientists and experienced land managers synthesize knowledge and original scientific work to address critical questions sparked by the decline of early successional habitats.
  • "Swaiman's Pediatric Neurology, by Drs. Kenneth Swaiman, Stephen Ashwal, Donna Ferriero, and Nina Schor, is a trusted resource in clinical pediatric neurology with comprehensive, authoritative, and clearly-written guidance. Extensively updated to reflect advancements in the field, this fifth edition covers new imaging modalities such as pediatric neuroimaging, spinal fluid examination, neurophysiology, as well as the treatment and management of epilepsy, ADHD, infections of the nervous system, and more. The fully searchable text is now available online at, along with downloadable images and procedural videos demonstrating intraventricular hemorrhage and white matter injury, making this an indispensable multimedia resource in pediatric neurology."--Publisher's website.
  • Anatomy of swallowing -- Physiology of swallowing -- Swallowing disorders: Clinical features & diagnosis -- Assessment of swallowing disorders -- Endoscopic management of swallowing disorders -- Radiological diagnosis in swallowing disorders -- Neurogenic dysphagia -- Medical management of swallowing disorders -- Pediatric dysphagia -- Presbyphagia.
  • Print Material
  • Print Material
    Cardiac symptoms and physical signs -- Congenital heart disease -- Valve disease -- The cardiomyopathies -- Coronary artery disease -- Cardiac failure -- Disturbances of cardiac rhythm : bradycardias, pacing, the ICD, biventricular pacing for heart failure -- Disturbances of cardiac rhythm : tachycardias and ablation -- Infective endocarditis -- Pericardial disease -- The heart in systemic disease -- Systemic hypertension -- Pulmonary hypertension and pulmonary embolism -- Diseases of the aorta -- Pregnancy and heart disease -- Cardiac investigations -- Echocardiography.
  • Biology, handling, husbandry, and anatomy -- Anesthesia, analgesia, and perioperative care -- Wound closure and integument -- Gastrointestinal procedures --Liver and biliary system -- Pancreas and spleen -- Urinary system and adrenal glands -- The reproductive system -- Cardiothoracic and vascular surgery/chronic intravascular catheterization -- Head and neck surgery/central nervous system -- Musculoskeletal system and orthopedic procedures -- Cardiovascular catheterization, electrophysiology, and imaging laboratory procedures -- Endoscopic, laparoscopic, and minimally invasive surgery -- Xenotransplantation and transgenic technologies --Toxicology -- Radiobiology -- Imaging techniques: CT, MRI, and PET scanning -- Ossabaw Island miniature swine: cardiometabolic syndrome assessment.
  • Swine influenza 2013
    Overview of Influenza Viruses / Stephan Pleschka -- History of Swine Influenza / Stacey Schultz-Cherry, Christopher W. Olsen, Bernard C. Easterday -- Genetics, Evolution, and the Zoonotic Capacity of European Swine Influenza Viruses / Roland Zell, Christoph Scholtissek, Stephan Ludwig -- History of Swine Influenza Viruses in Asia / Huachen Zhu, Richard Webby, Tommy T. Y. Lam, David K. Smith -- Clinicopathological Features of Swine Influenza / B. H. Janke -- Diagnostics and Surveillance for Swine Influenza / Susan Detmer, Marie Gramer, Sagar Goyal, Montserrat Torremorell -- Contemporary Epidemiology of North American Lineage Triple Reassortant Influenza A Viruses in Pigs / Alessio Lorusso, Amy L. Vincent, Marie R. Gramer, Kelly M. Lager -- History and Epidemiology of Swine Influenza in Europe / Ian H. Brown -- Swine Influenza Viruses: An Asian Perspective / Young-Ki Choi, Philippe Noriel Q. Pascua, Min-Suk Song -- Swine Influenza Virus Vaccines: To Change or Not to Change--That's the Question / Kristien Van Reeth, Wenjun Ma -- Swine Influenza Virus Infections in Man / Whitney S. Krueger, Gregory C. Gray -- Interspecies Transmission of Influenza A Viruses Between Swine and Poultry / Hadi M. Yassine, Chang-Won Lee, Yehia M. Saif -- The 2009 Pandemic Influenza Virus: Where Did It Come from, Where Is It Now, and Where Is It Going? / Ian York, Ruben O. Donis -- Pandemic Influenza A H1N1 in Swine and Other Animals / Julia Keenliside -- Therapeutics Against Influenza / Elena A. Govorkova, Jonathan A. McCullers.
  • Succinct guide to Windows users migrating to the Mac.
  • Print Material
    Contents -- Course 1. Inflammatory dermatoses, rewritten and rev. by H. Montgomery and E.B. Helwig -- Course 2. Granulomatous dermatoses, rev. by Tobias R. Funt [and others] -- Course 3. Nevi and neoplasms, rewritten and rev. by David W. Kersting [and others].
  • Print Material
  • Print Material
  • Print Material
    v. 1. Nutritional anemia / edited by Arthur Lejwa -- v. 2. Plasma proteins / edited by J.B. Youmans.
  • Print Material
  • Print Material
  • Print Material
  • Diagnostic process -- Screening and health maintenance -- Abdominal pain -- Acid-base abnormalities -- AIDS/HIV infection -- Anemia -- Back pain -- Bleeding disorders -- Chest pain -- Cough, fever, and respiratory infections -- Delirium and dementia -- Diabetes -- Diarrhea, acute -- Dizziness -- Dyspnea -- Dysuria -- Edema -- Fatigue -- Gi bleeding -- Headache -- Hematuria -- Hypercalcemia -- Hypertension -- Hyponatremia and hypernatremia -- Hypotension -- Jaundice and abnormal liver enzymes -- Joint pain -- Kidney injury, acute -- Rash -- Sore throat -- Syncope -- Weight loss, unintentional -- Wheezing and stridor.
  • This concise textbook of pediatric surgery is designed to guide the reader logically from symptoms and signs to diagnosis and treatment. Each chapter is devoted to one of 35 key symptoms and signs, which are organized according to six body regions: head, neck, chest, abdomen, urogenital system, and back. In each case, a brief assessment of the presenting sign/symptom and differential diagnosis is followed by discussion of occurrence, clinical presentation and significance, diagnostic work-up, treatment, and prognosis. Informative tables, illustrations, and up-to-date references are included throughout. Readers will also have access to an e-learning tool developed in collaboration with the Institute of Medical Education, University of Bern, which highlights the characteristics of pediatric surgical disorders and their treatment and includes clinical, radiological, and intraoperative images. Every physician and surgeon, whether specialist or generalist, who cares for children will find this book to be an invaluable source of information. It is based on the extensive personal experience of the author, which includes teaching at all levels and training of pediatric surgeons.
  • 1. Sound and Synapse / Laurence O. Trussell -- 2. Neuronal Response Properties and Voltage-Gated Ion Channels in the Auditory System / Nace L. Golding -- 3. The Hair Cell Synapse / Teresa Nicolson -- 4. The Endbulbs of Held / Paul B. Manis, Ruili Xie, Yong Wang, Glen S. Marrs, and George A. Spirou -- 5. The Calyx of Held Synapse / J.G.G. Borst and S.I. Rusu -- 6. Synaptic Mechanisms of Coincidence Detection / Katrina M. MacLeod and Catherine E. Carr -- 7. Inhibitory Neurons in the Auditory Brainstem / Laurence O. Trussell -- 8. Modulatory Mechanisms Controlling Auditory Processing / Raju Metherate -- 9. Mechanisms of Memory and Learning in the Auditory System / Thanos Tzounopoulos and Ricardo M. Leão.
  • Print Material
  • Part 1. Molecular organization of the pre- and postsynaptic scaffold -- Glutamate Receptors in Synaptic Assembly and Plasticity: Case Studies on Fly NMJs -- Scaffold Proteins at the Postsynaptic Density -- Diversity of Metabotropic Glutamate Receptor-Interacting Proteins and Pathophysiological Functions -- Regulation of the Actin Cytoskeleton in Dendritic Spines -- Synaptic Cell Adhesion Molecules -- Part 2. Molecular dynamics of the synapse -- Molecular Dynamics of the Excitatory Synapse -- The Brain's Extracellular Matrix and Its Role in Synaptic Plasticity -- Molecular Motors in Cargo Trafficking and Synapse Assembly -- Surface Traffic in Synaptic Membranes -- Synaptic Protein Degradation in Memory Reorganization -- AMPA Receptor Assembly: Atomic Determinants and Built-In Modulators -- Developmental Plasticity of the Dendritic Compartment: Focus on the Cytoskeleton -- Dendritic mRNA Targeting and Translation -- Gliotransmission and the Tripartite Synapse -- Part 3. Synapse-to-nucleus communication -- Roles of Neuronal Activity-Induced Gene Products in Hebbian and Homeostatic Synaptic Plasticity, Tagging, and Capture -- Long-Distance Signaling from Synapse to Nucleus via Protein Messengers -- Nuclear Calcium Signaling -- Integrating Neurotransmission in Striatal Medium Spiny Neurons -- Part 4.; Synaptic dysfunction and Synaptopathies -- Synaptic Dysfunction and Intellectual Disability -- Synaptic Pathology of Down Syndrome -- The Synaptic Pathology of Drug Addiction -- Synaptic Dysfunction in Schizophrenia -- Molecular and Cellular Aspects of Mental Retardation in the Fragile X Syndrome: From Gene Mutation/s to Spine Dysmorphogenesis -- Synaptic Dysfunction in Parkinson's Disease -- Synaptic Dysfunction in Alzheimer's Disease.
  • Many young, inexperienced doctors, have difficultly pinpointing a diagnosis: Is it a condition to which certain diseases could belong, or a disease definable in line with certain criteria? How can I apply my basic knowledge of diseases to a real patient? How can I find the correct diagnosis for a disease that I am seeing for the very first time? The traditional diagnostic pathways conveyed by current methods of teaching, from visual identification of the disease, knowledge of diseases, understanding of symptoms or patterns to diagnosis, leave certain diagnostic questions unanswered, especially on first experience of such a clinical pattern. Syndrome-based Approach to Diagnosis: A Practical Guide offers lecturers an alternative training concept in their teaching, which provides students with a model for self-study as well as the educational tools for learning how to think in clinical terms. It also includes a basic structured program for internal medicine at a glance in the form of decision trees that cover all major internal medicine fields. This training concept is suitable as: · A self-assessment test · A study program (self study and case-based study)· A basic program covering all the major teaching objectives in a clinical discipline· A guideline and educational framework for differential diagnosis · A collection of individual therapeutic options (with presentation of clinical cases)This book is a comprehensive educational tool ideal for medical professionals and those working within medical education.
  • Eyelids -- Lacrimal drainage system -- Orbit -- Dry eye -- Conjunctiva -- Cornea -- Corneal and refractive surgery -- Episclera and sclera -- Lens -- Glaucoma -- Uveitis -- Ocular tumours -- Retinal vascular disease -- Acquired macular disorders -- Hereditary fundus dystrophies -- Retinal detachment -- Vitreous opacities -- Strabismus -- Neuro-ophthalmology -- Ocular side effects of systemic medication -- Trauma.
  • Print Material
  • Improved understanding of the pathophysiologic changes in different diseases, including the molecular mechanisms of pathologic conditions such as tumors, has enhanced our ability to apply non-invasive techniques to investigate these diseases and permitted earlier detection and better management. It has also expanded the use of functional imaging, including molecular imaging. This synopsis is a companion to The Pathophysiologic Basis of Nuclear Medicine and arose from the recognition that there is a need for a compact, readable account of this complex and important subject. The companion book concisely describes relevant anatomic and physiologic considerations for each organ system and the pathophysiologic features of different relevant diseases, and relates them to the scintigraphy of each system. It thereby provides an informative synopsis of the pathophysiologic basis of nuclear medicine and molecular imaging. The volume will serve as a quick reference that will help the reader to understand different scintigraphic patterns and to select appropriate treatment modalities based on functional imaging. It will prove useful to undergraduates and postgraduates as well as to practitioners in clinical and research fields.
  • Synopsis of spine surgery. 2nd ed. 2008
    Thieme eNeurosurgery
    Anatomy and surgical approaches -- History and physical examination -- Spinal imaging and diagnostic tests -- Biomechanics of the spine and spinal instrumentation -- Physiology of bone grafts and bone graft substitutes -- Evaluation and management of spinal cord injury-- Spinal rehabilitation and disability evaluation -- Cervical spine trauma -- Thoracolumbar spine fractures -- Biomechanical aspects of intervertebral disc degeneration -- Degenerative cervical spine disorders: surgical and nonsurgical treatment -- Degenerative thoracic spine conditions -- Lumbar disc disease: pathogenesis and treatment options -- Lumbar spinal stenosis -- Surgical management of axial back pain -- Lumbar spondylolisthesis -- Scoliosis -- Kyphosic spinal deformities in children and adults -- Spinal tumors -- Spinal infections -- Rheumatoid arthritis -- Seronegative spondyloarthropathies -- Pediatric cervical spine disorders.
  • Introduction / Markus Schmidt -- That Was the Synthetic Biology That Was / Luis Campos -- An Introduction to Synthetic Biology / Carolyn M.C. Lam, Miguel Godinho and Vítor A.P. Martins dos Santos -- Computational Design in Synthetic Biology / Maria Suarez, Guillermo Rodrigo, Javier Carrera and Alfonso Jaramillo -- The Ethics of Synthetic Biology: Outlining the Agenda / Anna Deplazes, Agomoni Ganguli-Mitra and Nikola Biller-Andorno -- Do I Understand What I Can Create? Biosafety Issues in Synthetic Biology / Markus Schmidt -- Security Issues Related to Synthetic Biology Between Threat Perceptions and Governance Options / Alexander Kelle -- The Intellectual Commons and Property in Synthetic Biology / Kenneth A. Oye and Rachel Wellhausen -- Governing Synthetic Biology: Processes and Outcomes / Joyce Tait -- Synthetic Biology and the Role of Civil Society Organizations Shaping the Agenda and Arena of the Public Debate / Dirk Stemerding, Huib de Vriend, Bart Walhout and Rinie van Est -- Summary and Conclusions / Alexander Kelle.
  • Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms. Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomesHighlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications. Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development.
  • Mathematical models and design specifications in synthetic gene networks -- Robust synthetic biology designs based on system dynamic models -- Robust synthetic biology designs based on network evolutionary methods -- Construction of promoter and promoter-RBS libraries for synthesis of gene networks -- Robust synthetic gene network designs based on library-search method -- Robust design of synthetic biological filter and transistor based on promoter-RBS libraries -- Communication and synchronization of a population of coupled synthetic gene networks.
  • Syringomelia is a relatively rare clinical entity in which fluid-filled cavities develop within the spinal cord. Although modern imaging technologies usually permit an accurate diagnosis at an early stage, syringomyelia remains an enigmatic condition that continues to fascinate neurosurgeons, neurologists and other specialists. This reference monograph provides an up-to-date account of the present stateofunderstanding of syringomyelia and related disorders.The editors aim to document the best clinical practice in diagnosis and treatment and to provide clear guidance on how to reduce the incidence of severe outcomes. New challenges are addressed, including the appropriate management of the increasing number of apparently idiopathic syrinx cavities that are detected. In addition, controversies in current practice and directions for future research are fully discussed. Syringomelia will be an invaluable source of information for experts in the field, specialists in various related disciplines and other interested health care professionals.
  • Print Material
    The systematic approach to strabismus -- The four-part exam -- Approaching children and infants -- Approaching adults -- Extraocular muscles : anatomy and function -- Binocularity -- Differential diagnosis : ins, outs, ups, and downs -- Syndromes with ocular manifestations -- Nonsurgical treatment of strabismus.
  • A step-by-step learning text and atlas designed to teach essential and foundational skills of musculoskeletal physical assessment. Comprised of a 3-part learning system: 1. Screening Musculoskeletal Examination (SMSE): rapid assessment of structure and function 2. General Musculoskeletal Examination (GMSE): comprehensive assessment of joint inflammation and arthritis 3. Regional Musculoskeletal Examination (RMSE): focused assessments of structure and function combined with special testing of the shoulder, knee, and neck and low back.
  • "This wide-ranging study reviews the state of public health worldwide and presents informed recommendations for real-world solutions. Identifying the most urgent challenges in the field, from better understanding the causes of acute diseases and chronic conditions to reducing health inequities, it reports on cost-effective, science-based, ethically sound interventions. Chapters demonstrate bedrock skills essential to developing best practices, including flexible thinking for entrenched problems, conducting health impact assessments, and working with decision-makers. From these current findings come long-term practice and policy goals for preventing disease, promoting health, and improving quality of life, both locally and globally."--Publisher's website.
  • Rapid urbanisation, inequalities in income and service levels within and between communities, and population and economic decline are challenging the viability of rural communities worldwide. Achieving healthy and viable rural communities in the face of rapidly changing social, ecological and economic conditions is a declared global priority. As a result, governments all over the world, in both developed and developing countries, are now prioritizing rural and regional development through policies and programs aimed at enhancing the livelihoods of people living in rural regions. In recognition of the important roles that research can play in rural development, a range of systematic literature reviews have rightly examined key priorities in rural development including education, gender, economic development (especially agriculture), and health and nutrition (see Department for International Development [DFID], 2011). However, none of these works has systematically examined the extent to which rural development as a field of research is progressing towards facilitating sustainable change. This book evaluates trends in rural development research across the five continental regions of the world. Specifically, it assesses the total publication output relating to rural development, the types of publications, their quality and impact over the last three decades. Additionally, it evaluates the continental origins of the publications as well as the extent to which such publications engage with issues of sustainability. The aim is to determine whether the rural development field is growing in a manner that reflects research and policy priorities and broader social trends such as sustainability. Development policy makers, practitioners, those teaching research methods and systematic literature reviews to undergraduate and graduate students, and researchers in general will find the book both topical and highly relevant.
  • "This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover historical notes, general concepts on treatment with corticosteroids with regard to indications and side effects, and basic pharmacologic properties of these compounds. The rest of the book is devoted to the specific use of steroids in the different pediatric subspecialties. Despite advances with newer effective immunosuppressive and anti-inflammatory drugs, corticosteroids still remain the mainstay of therapy for many disorders. Leading authors in their field have summarized these concepts to provide an authoritative, comprehensive guide to help clinicians safely and effectively use corticosteroids in their pediatric patients."--Publisher's website.
  • Print Material
  • Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disease which can involve every organ system of the human body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness, or remission. Lupus is the prototypic autoimmune disease and SLE examines the entire field of autoimmunity by looking at lupus. There is no other book in the field which carefully covers scientific research, clinical findings, organ system involvement and treatment between its two covers. The fifth edition continues to serve as a vital translational reference for specialists in the diagnosis and management of patients with SLE, and as a key a tool for the measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries.
  • Print Material
    v. 1. Cardiovascular system, Respiratory system -- v. 2. Blood and bone marrow, Lymphoreticular system, Thymus gland -- v. 3. Alimentary system -- v. 4. Urinary system, Reproductive system, Breast, Endocrine system -- v. 5. Nervous system, Muscle, Bone, Joints -- v. 6. Skin, Eyes, Ears.
  • Print Material
  • Epigenetic modifications underlie all aspects of human physiology, including stem cell renewal, formation of cell types and tissues. They also underlie environmental impacts on human health, including aging and diseases like cancer. Consequently, cracking the epigenetic "code" is considered a key challenge in biomedical research. Chromatin structure and function are modified by protein complexes, causing genes to be turned on or off and controlling other aspects of DNA function. Yet while there has been explosive growth in the epigenetics field, human chromatin-modifying machines have only recently started to be characterized. To meet this challenge, our book explores complementary experimental tracks, pursued by expert international research groups, aimed at the physical and functional characterization of the diverse repertoire of chromatin protein machines - namely, the "readers, writers and erasers" of epigenomic marks. These studies include the identification of RNA molecules and drugs that interact selectively with components of the chromatin machinery. What makes this book distinctive is its emphasis on the systematic exploration of chromatin protein complexes in the context of human development and disease networks.
  • "Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance"--Publisher's description.
  • Print Material
    Molecular and Cellular Biology: An Engineering Perspective. Analysis: Signal Processing. Analysis: Control and Systems. Analysis: Probabilistic Data Networks and Communications. Design: Synthetic Biology. Integration: Reverse Engineering from Biology.
  • Systems biology 2013
    First, systems biology is an inter-disciplinary approach, requiring the combined talents of biologists, mathematicians, and computer scientists. Second, systems biology is holistic, with the goal of obtaining a comprehensive understanding of the workings of biological systems. This is achieved through the acquisition of massive amounts of data by high-throughput technologies-oligonucleotide microarrays, mass spectrometry, and next-generation sequencing-and the analysis of this data through sophisticated mathematical algorithms.
  • Systems biology 2007
  • The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions. Blood consists of circulating cells, cellular fragments (platelets and microparticles), and plasma macromolecules. Blood cells and their fragments result from a highly-ordered process, hematopoiesis. Definitive hematopoiesis occurs in the bone marrow, where pluripotential stem cells give rise to multiple lineages of highly specialized cells. Highly-productive and continuously regenerative, hematopoiesis requires a microenvironment of mesenchymal cells and blood vessels. A Systems Biology Approach to Blood is divided into three main sections: basic components, physiological processes, and clinical applications. Using blood as a window, one can study health and disease through this unique tool box with reactive biological fluids that mirrors the prevailing hemodynamics of the vessel walls and the various blood cell types. Many blood diseases, rare and common can and have been exploited using systems biology approaches with successful results and therefore ideal models for systems medicine. More importantly, hematopoiesis offers one of the best studied systems with insight into stem cell biology, cellular interaction, development; linage programing and reprograming that are every day influenced by the most mature and understood regulatory networks.
  • Part I. Systems biology in cancer -- Part II. Systems approaches to understand cancer progression -- Part III. Systems and network biology in decoding miRNA complexity -- Part IV. Network modeling in cancer drug discovery and clinical trials.
  • Modeling formalisms in systems biology of apoptosis / Stefan Kallenberger and Stefan Legewie -- Systems biology of death receptor-induced apoptosis / Kolja Schleich and Inna N. Lavrik -- Systematic complexity reduction of signaling models and application to a CD95 signaling model for apoptosis / Dennis Rickert, Nicolai Fricker, Inna N. Lavrik, and Fabian J. Theis -- Systems biology of the mitochondrial apoptosis pathway / Jochen H.M. Prehn, Heinrich J. Huber, and Carla O'Connor -- Systems biology of cell death in hepatocytes / Rebekka Schlatter, Kathrin Schmich, Christoph Borner, Michael Ederer, and Irmgard Merfort -- Understanding different types of cell death using systems biology / Laurence Calzone, Andrei Zinovyev, and Boris Zhivotovsky -- Modeling single cells in systems biology / Nicolai Fricker and Inna N. Lavrik -- Cytokine-cytokine cross talk and cell-death decisions / Christopher D. Deppmann and Kevin A. Janes -- Genetic and genomic dissection of apoptosis signaling / Christina Falschlehner and Michael Boutros.
  • Systems biology of bacteria 2012
    Focusing on the systems biology of bacteria and microorganisms, the 39th volume of Methods in Microbiology investigates the interface between molecular biology, bioinformatics, and modelling and predicting behavior. This cutting-edge research area is of extreme importance to the field and is developing quickly. Written by research experts in the field. Provides a guide for lab scientists, researchers, and students. Focuses on up-to-date research methods.
  • From Physiology, Genomes, Systems and Self-Organization to Systems Biology : The Historical Roots of a Twenty-First Century Approach to Complexity / M.A. Aon, D. Lloyd, and V. Saks -- Complex Systems Biology of Networks : The Riddle and the Challenge / Miguel A. Aon -- Systems Biology of Signaling Networks -- The Control Analysis of Signal Transduction / Hans V. Westerhoff, Samrina Rehman, Fred C. Boogerd, Nilgun Yilmaz, and Malkhey Verma -- MicroRNAs and Robustness in Biological Regulatory Networks. A Generic Approach with Applications at Different Levels : Physiologic, Metabolic and Genetic / Jacques Demongeot, Olivier Cohen, and Alexandra Henrion-Caude -- Dynamics of Mitochondrial Redox and Energy Networks : Insights from an Experimental-Computational Synergy / Sonia Cortassa and Miguel A. Aon -- Adenylate Kinase Isoform Network : A Major Hub in Cell Energetics and Metabolic Signaling / Song Zhang, Emirhan Nemutlu, Andre Terzic, and Petras Dzeja -- Systems Biology of Cellular Structures and Fluxes -- Moonlighting Function of the Tubulin Cytoskeleton : Macromolecular Architectures in the Cytoplasm / Judit Ovádi and Vic Norris -- Metabolic Dissipative Structures / Ildefonso Mtz. de la Fuente -- Systems Biology Approaches to Cancer Energy Metabolism / Alvaro Marín-Hernández, Sayra Y. López-Ramírez, Juan Carlos Gallardo-Pérez, Sara Rodríguez-Enríquez, Rafael Morena-Sánchez, and Emma Saavedra -- Systems Biology of Organ Function -- Network Dynamics in Cardiac Electrophysiology / Zhilin Qu -- Systems Level Regulation of Cardiac Energy Fluxes via Metabolic Cycles : Role of Creatine, Phosphotransfer Pathways, and AMPK Signaling / Valdur Saks, Uwe Schlattner, Malgorzata Tokarska-Schlattner, Theo Wallimann, Rafaela Bagur, Sarah Zorman, Martin Pelosse, Pierre Dos Santos, Franc̦ois Boucher, Tuuli Kaambre, and Rita Guzun -- Systems Biology of Microorganisms -- Temporal Partitioning of the Yeast Cellular Network / Douglas B. Murray, Cornelia Amariei, Kalesh Sasidharan, Rainer Machné, Miguel A. Aon, and David Lloyd -- Systems Biology and Metabolic Engineering in Bacteria / Johannes Geiselmann.
  • 1. Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease -- 2. The functions and regulatory principles of mRNA intracellular trafficking -- 3. RNA-binding proteins in regulation of alternative cleavage and polyadenylation -- 4. Functional analysis of long noncoding RNAs in development and disease -- 5. Piwi proteins and piRNAs step onto the systems biology stage -- 6. Manipulation of RNA using engineered proteins with customized specificity -- 7. Genetic variation and RNA binding proteins: tools and techniques to detect functional polymorphisms -- 8. Genome-wide activities of RNA-binding proteins that regulate cellular changes in the epithelial to mesenchymal transition (EMT) -- 9. Antisense oligonucleotide-based therapies for diseases caused by pre-mRNA processing defects -- 10. RNA-binding protein misregulation in microsatellite expansion disorders -- 11. RNA-binding proteins in heart development -- 12. Identification of miRNAs and their targets in C. elegans -- 13. Splicing code modeling -- Index.
  • Tuberculosis remains one of the world's biggest killers responsible for more than a million deaths each year. New drugs and new vaccines are urgently needed to tackle the disease. This book describes the application of this century's first new science, systems biology, to the study of tuberculosis. After introducing the basic principles of systems biology, successive chapters describe how systems-based approaches provide new insights into gene regulation, metabolism, protein-protein interaction, host-pathogen interactions, the immune response, persistence, drug treatment and diagnosis of tuberculosis. This book will be an invaluable aid to anyone interested in exploring how the latest science is helping us to understand this ancient disease.
  • Basic concepts of systems biology / Andrzej K. Konopka -- Understanding through modeling : a historical perspective and review of biochemical systems theory as a powerful tool for systems biology / Eberhard O. Voit and John H. Schwacke -- Thermostatics : a poster child of systems thinking / Peter Salamon, Anna Salamon, and Andrzej K. Konopka -- Friesian epistemology / Kelley L. Ross -- Reconsidering the notion of the organic / Robert E. Ulanowicz -- The metaphor of "chaos" / Wlodzimierz Klonowksi -- Biological complexity : an engineering perspective / Stephen W. Kercel -- The von Neumann's self-replicator and a critique of its misconceptions / Stephen W. Kercel -- The mathematical structure of thermodynamics / Peter Salamon ... [et al.].
  • The objective of this book is to present the strategies employed by living organisms on a molecular level and to help understand the basics of Systems Biology. Its content is organized in a way to meet the exponential growth in the volume of biological knowledge, and the need for a multidisciplinary approach in the practice of teaching modern biology. For this reason, the whole material is divided into five chapters, each devoted to a fundamental concept: Structure-Function, Energy, Information, Regulation and Interrelationships. The book describes generic mechanisms which occur in biology and promotes a simulation-based approach to the subject of Systems Biology. The use of basic knowledge as the background for presenting biological problems obligates the teachers to deal with generalized phenomena comprising the ever increasing volume of teaching materials.
  • Preface / Christoph Wittmann and Sang Yup Lee -- 1. Genome-scale network modeling / Sang Yup Lee, Seung Bum Sohn, Hyun Uk Kim, Jong Myoung Park, Tae Yong Kim, Jeffrey D. Orth, and Bernhard Ø. Palsson -- 2. Kinetic modeling of metabolic networks / Daniel C. Zielinski and Bernhard Ø. Palsson -- 3. Design of superior cell factories based on systems wide omics analysis / Katsunori Yoshikawa, Chikara Furusawa, Takashi Hirasawa, and Hiroshi Shimizu -- 4. Technologies for bio-systems engineering / Sonja Billerbeck, Sven Dietz, Gaspar Morgado, and Sven Panke -- 5. Systems metabolic engineering of Escherichia coli for chemicals, materials, biofuels, and pharmaceuticals / Dokyun Na, Jin Hwan Park, Yu-Sin Jang, Jeong Wook Lee, and Sang Yup Lee -- 6. Systems metabolic engineering of Corynebacterium glutamicum for biobased production of chemicals, materials and fuels / Judith Becker, Stefanie Kind, and Christoph Wittmann -- 7. Towards a synthetic biology of the stress-response and the tolerance phenotype: systems understanding and engineering of the Clostridium acetobutylicum stress-response and tolerance to toxic metabolites / Eleftherios T. Papoutsakis and Keith V. Alsaker -- 8. Model-based design of superior cell factory: an illustrative example of Penicillium chrysogenum / I. Emrah Nikerel, Peter J.T. Verheijen, Walter M. van Gulik, and Joseph J. Heijnen -- 9. Bridging omics technologies with synthetic biology in yeast industrial biotechnology / António Roldão, Il-Kwon Kim, and Jens Nielsen -- 10. Design of superior cell factories for a sustainable biorefinery by synthetic bioengineering / Tomohisa Hasunuma, Fumio Matsuda, and Akihiko Kondo -- 11. Systems-level analysis of cancer metabolism / Paulo A. Gameiro, Christian M. Metallo, and Gregory Stephanopoulos.
  • Part I. Brain-Machine Interfaces and Neurorehabilitation Brain-Computer Interfaces in the Rehabilitation of Stroke and Neurotrauma / Surjo R. Soekadar, Niels Birbaumer, and Leonardo G. Cohen -- Brain-Machine Interfaces for Persons with Disabilities / Kenji Kansaku -- Brain-Machine Interfaces Based on Computational Model / Yasuharu Koike, Hiroyuki Kambara, Natsue Yoshimura, and Duk Shin -- Improvement of Spastic Stroke Hemiparesis Using rTMS Combined with Motor Training / Satoko Koganemaru, Tatsuya Mima, Hidenao Fukuyama, and Kazuhisa Domen -- Molecular and Electrophysiological Approaches for Functional Recovery in Patients with Injured Spinal Cord / Toru Ogata, Noritaka Kawashima, Kimitaka Nakazawa, and Masami Akai -- Part II. Augmenting Cognition -- Prism Adaptation and the Rehabilitation of Spatial Neglect / Sophie Jacquin-Ciourtois, Jacinta O'Shea, Jacques Luauté, Laure Pisella, Alessandro Farné, Patrice Revol, Gilles Rode, and Yves Rossetti -- Toward a Cure Based on a Better Understanding of Autism Spectrum Disorder / Shigeru Kitazawa and Tamami Nakano -- Exceeding the Limits: Behavioral Enhancement Via External Influence / Katsumi Watanabe -- Neural Correlates of Reasoning by Exclusion / Akitoshi Ogawa.
  • Print Material

Access restricted to Stanford community

Shortcut to Licensed Content

Lane Gateway to Licensed Content

TO INSTALL, DRAG THIS BUTTON to your browser Bookmarks or Tools Bar.

What is it?

Lane Gateway to Licensed Content

Bookmark on Other Websites

Bookmark on Lane

  • TO INSTALL, RIGHT CLICK this button.
  • Select "Add to Favorites" (click “Continue” if you see a security alert)
  • From the "Create in" menu, select “Favorites Bar” (IE8, IE9) to install
  • Once installed it will look like this
  • Click "Bookmark on Lane" to bookmark any webpage
  • Your saved bookmark will appear on this page

What is it?

A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available. Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences. Includes cited reference searching, citation maps, and an analyze tool.Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not. Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.The National Guideline Clearinghouse (NGC): A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines. Over 10,000 notes outline the status of specific infections within each country.
Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.