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  • Towards a joint paradigm reconciling faith and research / Thomas St. James O'Connor and Elizabeth Meakes -- A critical dialogue between theology and psychology / Paul J. Rennick -- Assessing plurality in spirituality definitions / Pam McCarroll, Thomas St. James O'Connor, and Elizabeth Meakes -- Spirituality and family medicine / Cheryl Levitt -- Congregational life after abuse / Carol Penner -- Islamic spiritual care in a health care setting / Nazila Isgandarova -- Communication in spiritual care among people with dementia / Ellen Bouchard Ryan, Lori Schindel-Martin, and Amanda Beaman -- Spirituality and addiction / Lori Edey -- Spirituality in occupational therapy / Sue Baptiste -- Using a labyrinth in spiritual care / Ingrid Bloos -- A wholistic approach to healing : an individual, family, and community model / Calvin Morrisseau -- Old religion, new spirituality, and health care / Carlton F. Brown -- God-talk in the spiritual care of palliative patients / Colleen Lashmar -- Measuring and assessing suffering in arthritic patients / Beverley Clarke ... [et al.] -- Psychosomatics and the spiritual entities of the human psyche / Marie-Line Morin -- Life-threatening illness : a dangerous opportunity / Beverly Musgrave -- The neurobiology of consciousness and spiritual transformation in healing / Stephen M. Sagar.
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  • Spirituality in hospice palliative care 2013
    ebrary, Limited to 3 simultaneous users
    This groundbreaking book addresses the spiritual aspect of hospice care for those who do not fit easily within traditional religious beliefs and categories. A companion volume to Religious Understandings of a Good Death in Hospice Palliative Care, this work also advocates for renewed attention to the spiritual, the often overlooked element of hospice care. Drawing on data from clinical case studies, new sociological research, and the perspectives of agnostics, atheists, those who emphasize the spiritual rather than institutional dimensions of a traditional religion, and the rapidly growing cohort of those who describe themselves as spiritual-but-not-religious, the contributors to this volume interpret the shift from predominantly Christian-based pastoral services to a new approach to "the spiritual" shaped by the increasing diversity of Western societies and new understandings of the nature of secular society. How do we use it in a way that enables caregivers to assist patients? Clinicians and policy makers will appreciate the book's practical recommendations regarding staff roles, training, and resource allocation. General readers will be moved by the persuasive call for greater religious and spiritual literacy at every level of health care in order to respond to the full spectrum of human needs in life and in death. -- Publisher
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    "Since the publication of the first edition of Spirituality in Patient Care in 2002, the book has earned a reputation as the authoritative introduction to the subject for health professionals interested in identifying and addressing the spiritual needs of patients. The body of research on religion, spirituality, and health continues to grow at a dramatic rate, creating an urgent need for a new edition of this landmark work. In this, the third edition, Harold G. Koenig, M.D., updates every chapter by incorporating the newest research and introducing sensible ways of translating that research into caring for patients. Like previous editions, this new one addresses the whys, hows, whens, and whats of patient-centered integration of spirituality into patient care so that health professionals, including physicians in primary care and the medical and surgical specialties, can utilize this information in clinical practice. Whole chapters are also included offering profession-specific information for nurses, clergy, mental health professionals, social workers, and occupational and physical therapists. Other chapters address topics like culturally and spiritually sensitive care for each major religious group, potential limitations or barriers to application, and even what may happen when research on spirituality and health is misapplied. Throughout these chapters, readers will find new case histories and clinical examples on how to integrate spirituality into patient care depending on their particular circumstances. A ten-session model course curriculum on spirituality and health care for medical students and residents is also provided, with suggestions on how to adapt it for nursing, social work, physical and occupational therapy, and mental health training programs. For more than ten years Spirituality in Patient Care has offered sound guidance to anyone wishing to do more than simply treat their patients' physical symptoms. Treating the whole patient often requires becoming something more than just a skilled technician. With this new edition, Dr. Koenig once again shows the way for any health professional seeking to bridge this gap and help patients regain their lives by finding hope, meaning, and healing."--Provided by publisher.
  • The spiritual foundation: awareness and context for people's lives today / Peter Gilbert -- Values-based practice: help and healing within a shared theology of diversity / Bill (K.W.M.) Fulford and Kim Woodbridge -- Spirituality and mental health across cultures / Suman Fernando -- Loss and grief: spiritual aspects / Neil Thompson -- Through a glass darkly: looking for my own reflection / Sarah Carr -- A journey - with faith: complex travels with Islam through the mental health system / Mariyam Maule ... [et al.] -- Connecting past and present: a survivor reflects on spirituality and mental health / Vicky Nicholls -- Who am I?: the search for spirituality in dementia: a family carer's perspective / Barbara Pointon -- A chaplain's own story / Paul Chapple -- Keep up your spirits: run for your life! a view of running as a spiritual experience / Peter Gilbert -- Spiritual assessment: narratives and responses / Wendy Edwards and Peter Gilbert -- Spirituality and psychiatry: crossing the divide / Andrew Powell -- Spiritual competence: mental health and palliative care / Cameron Langlands, David Mitchell and Tom Gordon. Working with Qi (Chi) to help with mental health problems / Nigel Mills -- Spiritual practice day by day - conversations with those who know / Mary Ellen Coyte -- How different religious organizations can work constructively together / Azim Kidwai and Ali Jan Haider -- Organizational health: engaging the heart of the organization / Sarajane Aris and Peter Gilbert -- A plea for broad understanding: why mental health practitioners need to understand spiritual matters / Christopher MacKenna -- Promoting spiritual well-being in the workplace - training and support for staff / Frances Basset and Thurstine Basset -- Awakening the heart and soul: reflections from therapy / Brian Thorne -- Mental health care: the ultimate context for spiritual and pastoral formation / Julia Head and Mark Sutherland -- Researching spirituality and mental health - a perspective from the research / John Swinton -- Researching the soul: the Somerset Spirituality Project / John Foskett and Anne Roberts -- Concluding thoughts / Mary Ellen Coyte, Peter Gilbert and Vicky Nicholls.
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    Tuberculosis is a complex and ancient disease that, after many years of virtual disappearance in the developed world, is now making something of a comeback. Helen Bynum tracks the historical development of the disease and considers the challenges it presents to the modern world.
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    ch. 1. History and development of forensic medicine and pathology / Daniel J. Spitz -- ch. 2. Crime scene -- pt. 1. Bloodstain pattern interpretation / Herbert Leon MacDonell -- pt. 2. Biological evidence on the human body / Heather Miller Coyle, Carrl Ladd, Henry C. Lee -- pt. 3. Trace evidence / Richard E. Bisbing -- ch. 3. Time of death and changes after death -- pt. 1. Anatomical considerations / Joshua A. Perper -- pt. 2. Chemical considerations / William Q. Sturner -- pt. 3. Forensic entomology / Neil H. Haskell -- pt. 4. Exhumation / Michael Mm. Baden -- ch. 4. Identification of human remains -- pt. 1. Diverse techniques / Daniel J. Spitz -- pt. 2. DNA / Lynne M. Helton -- ch. 5. Anthropology / William M. Bass -- ch. 6. Forensic odontology -- pt. 1. Bite mark identification / Richard R. Souviron -- pt. 2. Advanced techniques in dental identification and bite marks / David Sweet -- pt. 3. Advanced photographic techniques / Gregory S. Golden -- pt. 4. The use of digital analysis in bite mark identification / C. Michael Bowers, Raymond J. Johansen -- ch. 7. Sudden and unexpected death from natural causes in adults / Barbara A. Sampson, Vernard I. Adams, Charles S. Hirsch -- ch. 8. Investigation of deaths in childhood -- pt. 1. Feticide and neonaticide / Werner U. Spitz, Daniel J. Spitz -- pt. 2. The abused child and adolescent / Marvin S. Platt, Daniel J. Spitz, Werner U. Spitz -- pt. 3. The differential diagnosis of child abuse / Marvin S. Platt, Lisa Kohler -- ch. 9. Trauma and disease / Vernard I. Adams, Mark A. Flomenbaum, Charles S. Hirsch -- ch. 10. Blunt force injury / Werner U. Spitz -- ch. 11. Sharp force injury / Werner U. Spitz -- ch. 12. Injury by gunfire -- pt. 1. Gunshot wounds / Werner U. Spitz -- pt. 2. Shotgun wounds / Werner U. Spitz -- ch. 13. Thermal injuries / Werner U. Spitz -- ch. 14. Asphyxia / Werner U. Spitz -- ch. 15. Investigation of bodies in water / Daniel J. Spitz -- ch. 16. Electrical and lightning injuries / Edmund R. Donoghue, Barry D. Lifschultz -- ch. 17. Road traffic victim / Werner U. Spitz -- ch. 18. Medicolegal investigation of mass disasters / Glenn N. Wagner, Richard C. Froede -- ch. 19. Trauma of the nervous system -- pt. 1. Forensic neuropathology / Vernon Armbrustmacher, Charles S. Hirsch -- pt. 2. Boxing injuries / Friedrich Unterharnscheidt, James M. Henry -- ch. 20. Microscopic forensic pathology / Joshua A. Perper -- ch. 21. Forensic aspects of radiology / B.G. Brogdon -- ch. 22. Investigation of deaths from drug abuse / Boyd G. Stephens -- ch. 23. Forensic aspects of alcohol / Werner U. Spitz -- ch. 24. The medicolegal autopsy report / Werner U. Spitz -- ch. 25. Selected procedures at autopsy / Werner U. Spitz.
  • Section I: Basic Principles, Diagnosis, and Non-surgical Management -- Spondylolisthesis: A Historical Perspective on Etiology, Diagnosis, and Treatment -- Anatomy and Biomechanics Relevant to Spondylolisthesis -- Pain Generators in Spondylolisthesis -- Clinical Evaluation of Pediatric Patients with Spondylolisthesis.-Clinical Evaluation of Adult Patients with Spondylolisthesis -- Imaging Techniques for the Diagnosis of Spondylolisthesis -- Classification of Spondylolisthesis -- Role of the Pelvis in the Diagnosis and Management of L5-S1 Spondylolisthesis.-Non-Operative Treatment of Spondylolisthesis -- Non-surgical Management of Spondylolisthesis in Children and Adolescents -- Non-surgical Management of Spondylolisthesis in Adults -- Section II: Surgical Techniques.-Surgical Techniques: Spondylolysis Repair.-Decompression and Spinal Fusion.-Surgical Techniques: Posterior Lumbar Interbody Fusion.-Anterior Lumbar Interbody Fusion (ALIF).-Minimally Invasive TLIF for Adult Spondylolisthesis.-Surgical Technique: Lateral Interbody Fusion for Adult Spondylolisthesis.-Pre-sacral Fusion for Adult Spondylolisthesis.-Surgical Techniques: Management of High-Grade Spondylolisthesis including Reduction Techniques.-Management of Spondyloptosis.-Management of Traumatic Spondylolisthesis: Cervical and Lumbar.-Spondylolisthesis Associated with Scoliosis.-Section III: Results of Treatment and Complications -- Results of Surgical Treatment of Adult Degenerative Spondylolisthesis -- Results of Surgical Treatment of Low Grade Adult Isthmic Spondylolisthesis.-Results of Surgical Treatment of Pediatric Spondylolysis and Spondylolisthesis.-Complications Associated with Surgical Treatment of Adult Spondylolisthesis.-Complications Associated with Surgical Treatment of Pediatric Spondylolisthesis -- Intraoperative Neuro-monitoring During Spondylolisthesis Surgery.-Value Considerations in the Surgical Management of Spondylolisthesis. Results of Surgical Treatment of Low Grade Adult Isthmic Spondylolisthesis.-Results of Surgical Treatment of Pediatric Spondylolysis and Spondylolisthesis.-Complications Associated with Surgical Treatment of Adult Spondylolisthesis.-Complications Associated with Surgical Treatment of Pediatric Spondylolisthesis -- Intraoperative Neuro-monitoring During Spondylolisthesis Surgery.-Value Considerations in the Surgical Management of Spondylolisthesis. Intraoperative Neuro-monitoring During Spondylolisthesis Surgery.-Value Considerations in the Surgical Management of Spondylolisthesis.
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    The macronutrients -- The micronutrients and water -- Digestion and absorption of the food nutrients -- Nutrient role in bioenergetics -- Macronutrient metabolism in exercise and training -- Measurement of energy in food and during physical activity -- Nutritional recommendations for the physically active person -- Nutritional considerations for intense training and sports competition -- Making wise choices in the nutrition marketplace -- Exercise thermoregulation, fluid balance, and rehydration -- Pharmacologic and chemical ergogenic aids evaluated -- Nutritional ergogenic aids evaluated -- Body composition assessment and sport-specific observations -- Energy balance, exercise, and weight control -- Disordered eating.
  • Georg Stuebinger verifies each of the 24 most common and deadliest cancer diseases worldwide including well-established and potential risk factors resp. important symptoms by using current literature and comprehensive scientific studies with a direct relation to the impact of various parameters of sports and exercise training such as training type, intensity, volume, duration and frequency complete with the corresponding effects. The impact of sports and exercise training as a potential therapy on reduced risk of cancer has been widely discussed in many scientific articles over the last few years, but is still widely unknown. In 2012, about 14 m cancer cases and 8.2 m cancer deaths appeared worldwide whereby cancer represents one of the most frequent causes of death accounting for approximately 13% with a continuously rising number.
  • Sudden cardiac death in athletes: scope of the problem and emergency response -- Cardiovascular screening of athletes: focused exam, electrocardiograms, and limited echocardiograms -- Echocardiography and advanced cardiac imaging in athletes -- Exercise training and prescription -- Role of genetic testing for sudden death predisposing heart conditions in athletes -- Shortness of breath -- Chest pain in the athlete: differential diagnosis, evaluation, and treatment -- The collapsed athlete -- Syncope/presyncope in the competitive athlete -- Electrophysiological approach to syncope and near-syncope in the athlete -- Heart murmurs -- Management of hypertension in athletes -- Hypertrophic cardiomyopathy -- Commotio cordis: practical aspects in sports -- Coronary artery anomalies and sports activities -- Participation in sports for the athlete with the Marfan syndrome -- Congenital heart disease: exercise and sports participation -- Athlete with a device: implantable cardioverter defibrillators and pacemakers -- Long QT syndrome and other channelopathies -- Cardiac effects of ergogenic aides and supplements -- Return-to-play decisions in athletes with cardiac conditions: guidelines and considerations.
  • This comprehensive reference textbook examines in detail physiological and pathophysiological aspects of the cardiovascular system and cardiovascular disease in the sporting population. In the first part of the book, the non-invasive and invasive diagnostic techniques employed in cardiology are systematically reviewed, with explanation of their indications and clinical utility. The second, more extensive part is devoted to clinical cardiology and covers the great majority of cardiological problems encountered among athletes and other sportsmen and -women. Syncope, cardiac arrhythmias, and sudden cardiac death are extensively addressed, and guidance is provided on sports practice for individuals with different forms of heart disease. Cardiologic rehabilitation is discussed, and attention is also paid to the legal implications of diagnosed or unsuspected cardiovascular diseases for sportspeople. Sports Cardiology will be an invaluable resource for trainee and experienced health care professionals, including in particular cardiologists and sports medicine physicians. It will provide the knowledge required in order to make critical decisions regarding eligibility, thereby preventing tragic events and especially sudden death - the most devastating occurrence in sport.
  • Sports dermatology 2006
  • Sports hernias are an increasingly recognized problem in athletics, presenting a challenge for team physicians and other health care providers regarding their diagnosis and management. Confusion is magnified by the various treatment methods that exist, both surgical and non-surgical. Sports Hernia and Athletic Pubalgia is the first text devoted solely to the topic of sports hernia and will examine its etiology and diagnosis, as well as how to differentiate it from other problems involving the athlete's hip area and other injuries it often correlates and interacts with, such as femoroacetabular impingement. It covers all current approaches to treatment, from open approaches to minimally invasive approaches, and discusses rehabilitation and return to play. Comprised of contributions from an international array of expert clinicians and thought leaders, this is the immediate authoritative book on the subject of sports hernias.
  • Preface -- Part I: Sports Injury Surveillance -- Sports Injury Surveillance in Japan (from Sports Safety Association) -- Sports Injury Surveillance in Japanese Junior and Senior High School Students -- Injury and Illness Surveillance among Olympic Athletes -- Part II: Concussion and Severe Head-Neck Injury -- Concussions in Junior Rugby Football Athletes and their Prevention -- Prevention of head and neck trauma in rugby -- Severe Head & Neck Injury and its Prevention in Judo -- Concussion and Severe Head-Neck Injury: An Approach for their Prevention in Rugby and Judo -- Part III: ACL Injury: Injury Mechanism, Prevention Programs and Their Usefulness -- Video analysis of ACL injuries in sports -- Video Analysis of ACL Injury Mechanisms Using a Model-Based Image-Matching Technique -- Injury Rate of Soccer Players and the Efficacy of the FIFA 11 + Program -- Biomechanical Studies on ACL Injury Risk Factor During Cutting; Utilizing the Point Cluster Technique -- Biomechanical Risk Factors and Prevention of Anterior Cruciate Ligament Injury -- Risk Factor Analysis of Female Soccer Tournament Players -- Prevention of Anterior Cruciate Ligament (ACL) Injury -- Anterior Cruciate Ligament Injury Prevention in Female Adolescents -- FIFA 11+ -- Injury Prevention in Amateur Football -- From Development to Worldwide Dissemination -- Influence of Changing Direction on the Center of Gravity and Knee Joint Angle in Rugby Players -- Anterior Cruciate Ligament Injury Prevention in Female Lacrosse Players Based on an Examination of Knee and Hip Joint Mechanics During Drop Vertical Jumps Performed While Holding a Lacrosse Stick -- ACL Injury Mechanism in Badminton: Survey of Injury Situation and Motion Analysis Study -- Part IV: ACL Injury: Post-Operative Rehabilitation, Recovery of Function and Tendon Regeneration -- Functional Hop Tests Contribute to Safe Return to Sports after Anterior Cruciate Ligament Reconstruction -- Biomechanical Adaptations in Subjects after Anterior Cruciate Ligament Reconstruction: Preventing Secondary Injury -- Morphology and Function of the Semitendinosus Muscle-Tendon Complex after Harvesting its Tendon for Anterior Cruciate Ligament Reconstruction -- Part V: Muscle Functions, Occurrence Mechanisms, and Program to Prevent Strain in the Hamstring Muscles -- Functional Differences among Hamstring Muscles in Hip Extension and Knee Flexion Exercises -- Anatomical and Functional Differences of Hamstrings -- Differences in Activation Patterns of the Hamstring Muscles during Sprinting -- The Relationship between Eccentric Exercise and Muscle Damage in Hamstring Muscles -- Risk factors and prevention of hamstring strain -- Part VI: Function in Arches of the Feet and Occurrence Mechanisms of Foot Disorders, Characteristics and Their Prevention -- Kinematics of the Foot and Ankle -- Biomechanical Analysis of the Effects of Footwear -- Risk Factors and Mechanisms of Fifth Metatarsal Stress Fracture -- Part VII: Lumbar Disorder and an Approach for Its Prevention -- Low Back Disorders Among Athletes and Its Prevention -- The Epidemiology of Low Back Disorders in Athletes -- The Prevention of Low Back Disorders in Divers -- Electromyographic Analysis of Deep Trunk Muscles During Sports Activities.
  • pt. 1. Sports injuries in youth : general aspects -- pt. 2. Injuries by anatomical location -- pt. 3. Common injuries in popular sports.
  • This introduction to sports injuries in children and adolescents is written in a user-friendly format and takes into account the fact that sports injuries in the pediatric population are not an easy topic for non-pediatric orthopedic surgeons, pediatricians, and non-pediatric radiologists. The book is divided into five chapters on musculoskeletal particularities in children, head and spine trauma, muscle strains and avulsion injuries, bone fractures, overuse injuries, and miscellanea. Each of these chapters comprises ten cases, and each case study includes up to four figures, a description of the clinical case, a review of the pathophysiology of the condition described in the case, and a final section on imaging findings. Sports Injuries in Children and Adolescents is a case-based book aimed at pediatricians, pediatric orthopedic surgeons, and radiologists.
  • Sports Injuries of the Foot is the go-to text for the management and treatment of foot injuries in athletes, demonstrating the current state-of-the-art techniques in assessment, testing and treatment. Organized anatomically beginning with the toes and working down the foot, it covers such common athletic injuries as turf toe, bunions, MTP instability, and midfoot and navicular fractures, all in the context of athletic activity. Attention is also given to special considerations for the adolescent and female athlete, with an eye toward return to play. Written by clinicians for clinicians, it will be an invaluable resource for orthopedists, podiatrists, team physicians, athletic trainers and primary care providers alike.
  • Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.
  • Sports knee surgery 2008
    Sect. I: Knee arthroscopy/meniscus procedures -- (Knee examination and imaging -- Knee arthroscopy-the basics -- Arthroscopic synovectomy -- Arthroscopic lysis of adhesions -- Arthroscopic meniscectomy -- Meniscal cyst and discoid meniscus -- Inside-out and outside-in meniscal repair -- All-inside meniscal repair -- Arthroscopically assisted meniscus transplantation) -- Sect. II: Articular cartilage procedures -- (Chondroplasty and microfracture -- Osteochondral autograft transplantation -- Autologous chondrocyte implantation -- Osteochondral allograft transplantation -- Osteochondritis dissecans -- Avascular necrosis and core decompression -- Opening wedge high tibial osteotomy -- Unicondylar knee arthroplasty) -- Sect. III: Knee ligament procedures -- (Single-bundle anterior cruciate ligament reconstruction -- Complex (double-bundle and revision) anterior cruciate ligament reconstruction -- Pediatric anterior cruciate ligament injuries -- Posterior cruciate ligament reconstruction -- Knee medial collateral ligament reconstruction -- Posterolateral corner reconstruction -- Multiple ligament injury) -- Sect. IV: Patellofmoral procedures -- (Acute and chronic patellar tendon ruptures -- Quadriceps tendon repair -- Arthroscopic lateral retinacular release -- Patellar tendionpathy -- Acute patella dislocation: medial patellofemoral ligament repair -- Patella fracture -- Proximal realignment: medal patellofemoral ligament reconstruction -- Distal realignment).
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  • Sports Medicine and Arthroscopic Surgery of the Foot and Ankle is an invaluable source of information for the sports medicine practitioner who performs foot and ankle surgery. All the common sports injuries of the foot and ankle that may require surgery are covered. The latest techniques, including arthroscopic approaches are highlighted. This unique text is designed to be a reference for all levels who want the best resource for their sports medicine foot and ankle patients who may require surgery.
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    Preparticipation physical evaluation / John L. Turner -- Sport psychology : psychological concepts and interventions / Chris Carr -- Tissue injury and healing / Sara Christensen Holz and Matthew Smuck -- The sports medicine approach to musculoskeletal medicine / Anthony Margherita -- Stretching and injury prevention / Vicki L. Voils and Nathan D. Prahlow -- Performance-enhancing sports supplements / Jeff Fields and John L. Turner -- Baseball injuries / Lance A. Rettig and Mark Ritter -- Racket sports injuries / Neeru Jayanthi and Jay V. Subbarao -- Golf injuries / Andrea L. Aagesen and Shashank J. Dave -- Swimming and diving injuries / Kevin M. Marberry and Dawn Schisler -- Road cycling injuries / Julia J. Walker and Shashank J. Dave -- Mountain biking injuries / Matthew Smuck -- Football injuries / Gerard A. Malanga, Jason Peter, and Dennis A. Bandemer, Jr. -- Soccer injuries / Elizabeth A. Grossart and Johnny G. Owens -- Running injuries / Michael Khazzam and Kevin M. Marberry -- Skiing and snowboarding injuries / Peter W. Bailey, Andrea J. Boon, and Eric J. Watson -- Gymnastics injuries / Grant Lloyd Jones, Todd C. Miller, and Donald C. LeMay -- Basketball injuries / Meenakshi Garg, Peter I. Sallay, and Patti Hunker -- Volleyball injuries / Nathan D. Prahlow -- Weight-training injuries / Jess D. Salinas, Jr. -- Women's musculoskeletal issues / Gary P. Chimes -- Musculoskeletal issues in the elderly / Nabiha N. Gill -- Health benefits of exercise / Angela T. Carbone and Albert Gunjan Singh.
  • Sideline physician / John H. Wilckens -- Preparticipation evaluation / Jay E. Noffsinger -- Team physician's bag / Scott D. Flinn and Elise T. Gordon -- Mass-participation event coverage / Scott W. Pyne -- Emergency planning for athletic events / Scott D. Flinn and Timothy Dwyer -- Victim or culprit: a pathoanatomic approach to the correct diagnosis / Anthony I. Beutler -- Physical examination of the wrist and hand / William A. Mitchell III and Ahmed A. Radwan -- Physical examination of the elbow / Thomas M. Howard, Joel L. Shaw and James Phillips -- Physical examination of the shoulder / Sean T. Mullendore -- Physical examination of the cervical and thoracic spine / Derek A. Woessner and Charles W. Webb -- Physical examination of the lumbar spine / Philip Ham and James D. Leiber -- Physical examination of the hip and pelvis / Peter H. Seidenberg and Marc A. Childress -- Physical examination of the knee / Nicholas A. Piantanida and Nicole T. Yedlinsky -- Physical examination of the foot and ankle / Karl B. Fields, Wesley R. Ibazebo and Ryan E. Modlinski -- General principles of fracture management / Howard J. McGowan -- Splinting and casting / Timothy J. Mazzola -- Radiographic lines and angles / Peter H. Seidenberg -- Wrist and hand fractures / Stephen J. Titus and W. Scott Deitche -- Soft-tissue injuries of the hand and wrist / Chad Asplund and Christopher D. Meyering -- Elbow injuries / Mark A. Slabaugh -- Injuries of the shoulder and arm -- pt. A. Soft-tissue shoulder injuries / Patrick St. Pierre and Rodney Gonzales -- pt. B. Shoulder fractures and clavicular joint injuries / Patrick St. Pierre and Rodney Gonzales -- Craniomaxillofacial injuries / Allyson S. Howe -- Cervical spine injuries / Barry P. Boden -- Thoracic and lumbar spine injuries / Charles W. Webb and Richard Geshel -- Pelvic pain in the athlete / Adam J. Farber, John H. Wilckens and Christopher G. Jarvis -- Knee injuries / Andrew T. McDonald and Lyndon B. Gross -- Lower leg injuries / Greg Dammann and Duane R. Hennion -- Ankle fractures / Shawn E. Kane -- Foot fractures / Kevin deWeber -- Foot and ankle soft-tissue injuries / Ahmed A. Radwan, Peter H. Seidenberg and Greg Dammann -- Pediatric and adolescent injuries -- pt. A. Treatment of common pediatric and adolescent conditions / Mark B. Stephens -- pt. B. Spondylolysis: a practical approach to an adolescent enigma / Francis G. O'Connor, Pierre A. d'Hemecourt and Melissa Nebzydoski -- Stress fractures / Christopher M. Prior and Jessica A. Pesce -- Principles of sports rehabilitation / Jennifer Reed and Jimmy D. Bowen -- Practical application of osteopathic manipulation in sports medicine / Lori A. Boyajian-O'Neill and Dennis A. Cardone -- Core stabilization / Daniel L. Munton, Geof D. Manzo and Elizabeth J. Caschetta -- Physical therapy modalities / Guy R. Majkowski and Norman W. Gill III -- Athletic taping / Raymond D. Chronister and Gregg Calhoon -- Proper indications and uses of orthopedic braces / Jeff C. Leggitt and Christopher G. Jarvis -- Exercise prescription / David D. Farnsworth and Michael Cannon -- Cardiovascular testing / David A. Djuric and Francis G. O'Connor -- Testing for maximal aerobic power / Patricia A., Deuster and Yuval Heled -- Exercise-induced asthma testing / Rochelle M. Nolte and Christopher J. Lettieri -- Gait analysis / Timothy L. Switaj and Francis G. O'Connor -- Concussion testing and management / Scott A. Playford -- Running shoes: assessment and selection / Charles W. Webb and Marc A. Childress -- Compartment syndrome testing / Brandon D. Larkin and Janiece N. Stewart -- Electrodiagnostic testing / Jimmy D. Bowen -- Therapeutic and diagnostic injections and aspirations / Thomas M. Howard and Leslie H. Rassner -- Ergogenic aids / Jeffrey I. Levy [and others] -- Evidence-based regenerative injection therapy (prolotherapy) in sports medicine / K. Dean Reeves, Bradley D. Fullerton and Gaston Topol -- Team physician consensus statement -- Sports and physical activity in youth / Bernard Purcell and Mark B. Stephens -- Exercise prescription for pregnant patients / Pamela M. Williams and Michael Barron -- Exercise prescription for geriatric patients / Brian K. Unwin.
  • Sports medicine surgery 2010
  • "Many sports nutrition professionals are challenged by their lack of knowledge of both the functional limitations and the required alterations to training of the athlete with an impairment. In cases where the impairment results in minimal differences in the physiological basis of exercise, sports nutrition principles are easily transferable. However, other impairments such as spinal cord injuries, spina bifida, and cerebral palsy require a very individualized approach to estimations of energy expenditure and carbohydrate and fluid requirements. 'Sports Nutrition for Paralympic Athletes' provides information on the broad subcategories of all physical impairments, along with visual, hearing, and intellectual impairments. Specific areas such as body composition, supplements, and practical issues are discussed comprehensively. Case studies enhance and illustrate a direct and first-hand application to managing Paralympic athletes. Sports nutrition can be the difference in being competitive and making the podium. With the rapidly increasing Paralympic profile, this book will be required reading for professionals endeavoring to give their athletes the competitive edge. This book will challenge and stimulate current and future research in this area to improve the delivery of this intrinsic component of athlete preparation"--Provided by publisher.
  • Carbohydrate ingestion during exercise : effects on performance, training adaptations, and trainability of the gut / Jeukendrup, A.E.; McLaughlin, J. -- Altering endogenous carbohydrate availability to support training adaptations / Philp, A., Baar, K., Burke, L.M. -- Metabolic regulation of fat use during exercise and in recovery -- Spriet, L.L. -- Fat adaptation science : low-carbohydrate, high-fat diets to alter fuel utilization, and promote training adaptation / Hawley, J.A. -- Dietary protein to support muscle hypertrophy / van Loon, L.J.C., Gibala, M.J. -- Effect of protein, dairy components, and energy balance in optimizing body composition / Phillips, S.M., Zemel, M.B. -- Effect of cell hydration on metabolism / Lang, F. -- Practical nutritional recommendations for the athlete -- Maughan, R.J., Burke, L.M.
  • Introduction to sports nutrition: energy metabolism / Barry Braun and Benjamin F. Miller -- Utilization of carbohydrates in energy production / J. Andrew Doyle, Charilaos Papadopoulos, and Michael S. Green -- Utilization of fats in energy production / Serge P. von Duvillard ... [et al.] -- Utilization of proteins in energy metabolism / Mauro G. Di Pasquale -- Laboratory methods for determining energy expenditures of athletes / Robert G. McMurray and Kristin S. Ondrak -- Field assessment of physical activity and energy expenditure among athletes / Kelley K. Pettee, Catrine Tudor-Locke, and Barbara E. Ainsworth -- Influence of dietary fiber on body weight regulation / Daniel D. Gallaher -- Nutritional implications of sex and age differences in energy metabolism / A.C. Maher and Mark A. Tarnopolsky -- Body weight regulation and energy needs / Melina M. Manore and Janice L. Thompson.
  • Introduction to sports nutrition: fats and proteins / John J.B. Anderson -- Total fats, saturated fats, and cholesterol / Heather E. Rasmussen and Ji-Young Lee -- Medium-chain triglycerides / Wayne E. Billon -- Omega-3 and omega-6 fatty acids / Karina R. Lora and Nancy M. Lewis -- Conjugated linoleic acid / Celeste G. Koster and Martha A. Belury -- Octacosanol and wheat germ oil / Susan H. Mitmesser -- Protein: quantity and quality / Mark A. Tarnopolsky and Brian W. Timmons -- Whey, casein, and soy proteins / Brian S. Synder and Mark D. Haub -- Creatine / Richard B. Kreider -- Glucosamine and chondroitin sulfate / Catherine G.R. Jackson -- Carnitine / Sara Chelland Campbell and Robert J. Moffatt -- [Beta]-Hydroxy-[Beta]-Methylbutyrate / Steven L. Nissen -- Branched-chain amino acids / Michael Gleeson -- Glutamine / Satya S. Jonnalagadda -- Other individual amino acids / Neal F. Spruce and C. Alan Titchenal -- Recommended proportions of carbohydrates to fats to proteins in diets / Henry C. Lukaski. Introduction to sports nutrition: fats and proteins / John J.B. Anderson -- Total fats, saturated fats, and cholesterol / Heather E. Rasmussen and Ji-Young Lee -- Medium-chain triglycerides / Wayne E. Billon -- Omega-3 and omega-6 fatty acids / Karina R. Lora and Nancy M. Lewis -- Conjugated linoleic acid / Celeste G. Koster and Martha A. Belury -- Wheat germ oil and octacosanol / Susan H. Mitmesser -- Protein, quantity and quality / Mark A. Tarnopolsky and Brian W. Timmons -- Whey, casein, and soy proteins / Brian S. Synder and Mark D. Haub -- Creatine / Richard B. Kreider -- Glucosamine and chondroitin sulfate / Catherine G.R. Jackson -- Carnitine / Sara A. Chelland-Campbell and Robert J. Moffatt -- Beta-Hydroxy-Beta-Methylbutyrate / Steven L. Nissen -- Branched-chain amino acids / Michael Gleeson -- Glutamine / Satya S. Jonnalagadda -- Other individual amino acids / Neal F. Spruce and Alan Titchenal -- Recommended proportions of carbohydrates to fats to proteins in diets / Henry C. Lukaski.
  • Sports performance 2015
  • In the past decade, few issues at the intersection of medicine and sports have had as high a profile or have generated as much public interest as sports-related concussions. In recent years there has been a growing awareness and understanding that all concussions involve some level of injury to the brain and that athletes suspected of having a concussion should be removed from play for further evaluation (CDC, 2013; Halstead et al., 2010). Despite the increased attention, however, confusion and controversy persist in many areas, from how to define a concussion and how multiple concussions affect the vulnerability of athletes to future injury, to when it is safe for a player to return to sports and the effectiveness of protective devices and other interventions in reducing the incidence and severity of concussive injuries (Wilde et al., 2012). Parents worry about choosing sports that are safe for their children to play, about finding the equipment that can best protect their children, and about when, if a child does receive a concussion, it will be safe for him or her to return to play or if it might be time to quit a much-loved sport entirely. It is within this context that the Institute of Medicine (IOM) and National Research Council (NRC), in October 2012, convened the Committee on Sports-Related Concussions in Youth to review the science of sports-related concussions in youth from elementary school through young adulthood, including military personnel and their dependents, and to prepare a report on that topic based on that review. The committee was charged with reviewing the available literature on concussions within the context of developmental neurobiology, specifically relating to the causes of concussions, their relationship to impacts to the head or body during sports, the effectiveness of protective devices and equipment, screening for and diagnosis of concussions, their treatment and management, and their long-term consequences.
  • General Issues. Historical Overview of Familial Gastric Cancer / Giovanni Corso -- Frequency of Familial Gastric Cancer / Giovanni Corso, Daniele Marrelli -- The Family Cancer Database / Giovanni Corso, Daniele Marrelli, Franco Roviello -- Genetics and Epigenetics. The E-Cadherin Gene, Structure and Function / Francesco Graziano -- E-Cadherin Germline Mutations / Joana Carvalho, Hugo Pinheiro, Carla Oliveira -- Molecular Mechanisms of Hereditary Diffuse Gastric Cancer Initiation and Progression / Parry Guilford, Bostjan Humar -- Germline Missense Mutants in Hereditary Diffuse Gastric Cancer / Joana Figueiredo, Raquel Seruca -- Alternative Mechanisms to Germline CDH1 Mutations in Hereditary Diffuse Gastric Cancer / Hugo Pinheiro, Joana Carvalho, Carla Oliveira -- Beyond CDH1 Mutations: Causes of Hereditary Diffuse Gastric Cancer / Samantha Hansford B.Sc., David Huntsman, FRCPC -- Non-CDH1-Associated Familial Gastric Cancer and Epigenetics Factors / Marina Leite, Giovanni Corso, Sónia Sousa, Joana Carvalho -- Pathology. Hereditary Diffuse Gastric Cancer and Lobular Breast Carcinoma / Gisela Keller -- Pathology of Hereditary Gastric Cancer / Fátima Carneiro -- Management. Clinical Criteria for Familial Gastric Cancer Definition / Giulia De Falco, Alessandro Davide Videtta -- Prophylactic Total Gastrectomy in CDH1 Germline Mutation Carriers / Francesco Ferrara, Giovanni Corso, Franco Roviello -- Gastric Cancer in Other Inherited Syndromes / Giovanni Corso, Sérgia Velho -- Clinical Management of Familial Gastric Cancer / Giovanni Corso, Daniele Marrelli, Franco Roviello -- Appendix / Giovanni Corso
  • v. 1. Class 5: Isomerases -- v. 2. Class 6: Ligases -- v. 3. Class 4: Lyases I -- v. 4. Class 4: Lyases II -- v. 5. Class 4: Layases III -- v. 6. Class 3.4: Hydrolases I -- v. 7. Class 3.4: Hydrolases II -- v. 8. Class 3.4: Hydrolases III -- Index A: Synonym -- v. 9. Class 3.1: Hydrolases IV -- v. 10. Class 3.1: Hydrolases V -- v. 11. Class 3.1: Hydroclass VI -- v. 12. Class 3.2: Hydrolases VII -- v. 13. Class 3.2: Hydrolases VIII -- v. 14. Class 3.2-3.5: Hydrolases IX -- v. 15. Class 3.5-3.12: Hydrolases X -- v. 16. Class 1: Oxidoreductases I -- v. 17. Class 1: Oxidoreductases II -- v. 18. Class 1: Oxidoreductases III -- v. 19. Class 1: Oxidoreductases IV -- v. 20. Class 1: Oxidoreductases V. Class 1: Oxidoreductases VI -- v. 22. Class 1: Oxidoreductases VII -- v. 23. Class 1: Oxidoreductases VIII. -- v. 24. Class 1: Oxidoreductases IX -- v. 25. Class 1: Oxidoreductases X -- v. 26. Class 1: Oxidoreductases XI -- v. 27. Class 1: Oxidoreductases XII -- v. 28. Class 2: Transferases I -- v. 29. Class 2: Transferases II -- v. 30. Class 2: Transferases III -- v. 31. Class 2: Transferases IV -- v. 32. Class 2: Transferases V -- v. 33. Class 2: Transferases VI EC -- v. 34. Class 2: Transferases VI EC -- v. 35. Class 2: Transferases VIII -- v. 36. Class 2: Transferases IX -- v. 37. Class 2: Transferases X -- v. 38. Class 2: Transferases XI -- v. 39. Class 2: Transferases XII -- v. S1. Class 1: Oxidoreductases EC 1 -- v. S2. Class 2: Transferases EC 2.1-2.7.10 -- v. S3. Class 2: Transferases EC -- v. S4. Class 2: Transferases EC -- v. S5. Class 3: Hydrolases EC 3.1-3.4.21 -- v. S6. Class 3: Hydrolases EC3.4.22-3.13 -- v. S7. Class 4-6: Lyases, Isomerases, Ligases EC 4-6.
  • Springer series on biofilms v. 1-, 2007-
  • SPSS for dummies 2007
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  • SPSS for starters 2010
    Introduction -- One-Sample Continuous and Binary Data (t-Test, z-Test) (10 and 55 Patients) -- Paired Continuous Data (Paired-t, Wilcoxon) (10 Patients) -- Unpaired Continuous Data (Unpaired t-Tests, Mann-Whitney) (20 Patients) -- Linear Regression (20 Patients) -- Repeated Measures ANOVA, Friedman (10 Patients) -- Mixed Models (20 Patients) -- One-Way-ANOVA, Kruskall-Wallis (30 Patients) -- Trend Test for Continuous Data (30 Patients) -- Unpaired Binary Data (Chi-Square, Crosstabs) (55 Patients) -- Logistic Regression (55 Patients) -- Trend Tests for Binary Data (106 Patients) -- Paired Binary (McNemar Test) (139 General Practitioners) -- Multiple Paired Binary Data (Cochran's Q Test) (139 Patients) -- Cox Regression (60 Patients) -- Cox Regression with Time-dependent Variables (60 Patients) -- Validating Qualitative Diagnostic Tests (575 Patients) -- Validating Quantitative Diagnostic Tests (17 Patients) -- Reliability Assessment of Qualitative Diagnostic Tests (17 Patients) -- Reliability Assessment of Quantitative Diagnostic Tests (17 Patients) -- Final Remarks.
  • SQL cookbook 2006
    ProQuest Safari
    Retrieving records -- Sorting query results -- Working with multiple tables -- Inserting, updating, deleting -- Metadata queries -- Working with strings -- Working with numbers -- Date arithmetic -- Date manipulation -- Working with ranges -- Advanced searching -- Reporting and warehousing -- Hierarchical queries -- Odds 'n' ends.
  • SQL for dummies. 6th ed. 2006
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  • SQL functions programmer's reference 2005
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    SQL fundamentals -- Joins, unions, and views -- Text handling -- Date handling -- Number crunching -- Online applications -- Organizing data -- Storing small amounts of data -- Locking and performance -- Reporting -- Users and administration -- Wider access.
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    Staff development and training are essential to ensure that libraries meet new challenges and fulfill their missions, especially in a constantly changing world where technological innovations directly impact information access. This new edition offers unique, state-of-the-art perspectives on important topics in staff training.
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    Structure and function of neurons -- Synaptic neurotransmission and the anatomically addressed nervous system -- Signal transduction and the chemically addressed nervous system -- Transporters and G protein-linked receptors as targets of psychopharmacological drug action -- Ion channels and enzymes as targets of psychopharmacological drug action -- Psychiatric genetics -- Circuits in psychopharmacology -- From circuits to symptoms in psychopharmacology -- Psychosis and schizophrenia -- Antipsychotic agents -- Mood disorders -- Antidepressants -- Mood stabilizers -- Anxiety disorders and anxiolytics -- Pain and the treatment of fibromyalgia and functional somatic syndromes -- Disorders of sleep and wakefulness and their treatment -- Attention deficit hyperactivity disorder and its treatment -- Disorders of reward, drug abuse, and their treatment.
  • v. 1. Pre-analytic publications and unpublished drafts -- v. 2. Studies on hysteria -- v. 3. Early analytic publications -- v. 4. The interpretation of dreams (1) -- v. 5. The interpretation of dreams (II) -- v. 6. The psychopathology of everyday life -- v. 7. A case of hysteria, Three essays on sexuality, and other works -- v. 8. Jokes and their relation to the unconscious -- v. 9. Jensen's G̀radiva' and other works -- v. 10. The cases of L̀ittle Hans' and the R̀at Man' -- v. 11. Five lectures on psycho-analysis, Leonardo and other works -- v. 12. Case history of Schreber, Papers on technique, and other works -- v. 13. Totem and taboo and other works -- v. 14. A history of the psycho-analytic movement, Papers on metapsychology, and other works -- v.15. Introductory lectures on psycho-analysis (1) -- v. 16. Introductory lectures on psycho-analysis (II) -- v. 17. An infantile neurosis and other works -- v. 18. Beyond the pleasure principles, Group psychology, and other works -- v. 19. The ego and the Id and other works -- v. 20. An autobiographical study, Inhibitions, symptoms and anxiety, Lay analysis, and other works -- v. 21. The future of an illusion, Civlilization and its discontents, and other works -- v. 22. New introductory lectures and other works -- v. 23. Moses and monotheism, An outline of psycho-analysis and other works -- v. 24. Indexes, Bibliography, etc.
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    v. 1. Suggested standards for homes for the aged and nursing homes -- v. 2. Methods of establishing and maintaining standards -- v. 3. Bridging the gap between existing practices and desirable goals in homes for the aged and nursing homes.
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    Consists of a photographic record and landscape architectural layout of 22 benches containing a collection of personal stories about medical education, treatment, and research at Stanford. These thematically arranged granite benches/planters tied to chronological highlights of the history of medicine in paving stones constitute the Discovery Walk. The story includes conversations with over 200 research and clinical faculty, as well as students, staff, and alumni from the Stanford Community. The project was commissioned by Dean Philip Pizzo in 2008 for the centennial of the medical school and was dedicated in the spring of 2012. The Project also includes the Foundation Walk, a chronology of the school since its founding in 1858, and the Landscape Plan which creates an entrance to the School of Medicine and connection to the broader campus.
  • Message from the Chairman -- Cerebrovascular neurosurgery and stroke -- Stroke research --Neural Stem Cell Program -- Saving neurons from stress (exogenous migratory therapy) -- Pediatric Neurosurgery -- Stanford Center for Children's Brain Tumors -- Functional neurosurgery (movement disorders, epilepsy and pain) -- Stanford Brain Tumor Center -- CyberKnife radiosurgery -- Brain tumor research (testing a vaccine against glioblastomas) -- Stanford Pituitary Center and Skull Base Tumor Program -- NeuroSpine Program -- Partnership for spinal cord injury and repair -- NeuroSpine research -- NeuroTrauma -- Community outreach programs -- Neurosurgery nurses -- Neurosurgery education and training -- Donors to Stanford Neurosurgery -- Recent Stanford Neurosurgery publications.
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    "This book had its genesis in the need created by my involvement with undergraduate teaching starting in the Fall of 1970 when I was a resident fellow and taught a course on sleep for the students in my dormitory. The course began to attract other students and because of this I decided to offer a formal presentation in Winter Quarter 1971 and I have offered a course on sleep annually up until Winter Quarter 2003. Sleep and Dreams was not offered in 2004 or 2005 but due to high student demand, we resurrected the course for the Winter Quarter 2006. Around 1980, the various handouts developed into a quasi-textbook and by the middle of the 90s, the first Stanford Sleep Book was born. The current volume is the 5th edition"--Acknowledgements.
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    Appendix at end includes list of presidents, 1959-2015, thank you letter from Amir Dan Rubin, list of gifts to the Medical Center, 1959-2008 ($4.3M); services to Stanford Hospital, 1983-2014; scholarships, 1971-May 2014 ($1M); volunteer hours (over 3 million); and copy of the Auxiliary stationery, 1929.
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  • This book follows Starting to Read ECGs: The Basics by the same authorship and provides the beginner in electrocardiogram (ECG) interpretation with a concise, practical and systematic guide to interpreting ECGs. The authors have included an introduction to the pediatric ECG and genetic cardiac conditions in attempt to deepen readers awareness of some of the broader clinical issues. Starting to Read ECGs: A Comprehensive Guide to Theory and Practice expands on some of the topics introduced in the first book, but offers a deeper perspective with more detailed background information and a variety of practical interpretation methods. It can be read as a standalone book for those who already possess some basic ECG knowledge or for those who have read the first book in the series and wish to consolidate and expand on what they have already read. The book uses numerous diagrams, tables and practical examples to reinforce learning and summarize information succinctly, and will be an essential resource for medical students, junior doctors, and other health care professionals involved in the recording and interpretation of ECGs who wish to build their knowledge and confidence.
  • Chapter 1: How to record a 12-lead ECG -- Physiology -- What is an ECG -- Patient positioning -- Electrode placement -- Attaching the cables -- The machine -- What to write on the ECG -- Summary of key points -- Quiz -- Chapter 2: ECG basics -- How does the 12-lead ECG work? -- ECG paper -- Details found on a standard 12-lead ECG -- 12-lead ECG leads -- The PQRST waveform -- Deflection -- Summary of key points -- Quiz -- Chapter 3: Quality issues pertaining to ECG recording -- Background -- Leads -- Calibration markers -- ECG Documentation -- Summary of key points -- Quiz -- Chapter 4: Principles of ECG analysis -- Background -- Basic quality control checks -- The rate -- The rhythm -- The P wave -- The PR interval -- The QRS complex -- The ST segment -- The T wave -- The QT interval -- Electrical axis -- Additional features -- The normal ECG and normal variants -- Summary of key points -- Quiz -- Chapter 5: Chamber abnormalities -- Physiology -- Atrial abnormality -- Ventricular abnormality -- Normal variants -- Summary of key points -- Quiz -- Chapter 6: Arrhythmias -- Background -- Ectopic beats -- Atrial arrhythmias -- Junctional arrhythmias -- Ventricular Arrhythmias -- Summary of key points -- Quiz -- Chapter 7: Conduction delay -- Background -- Bundle Branch Blocks -- Atrioventricular Blocks (AV Blocks) -- Sinoatrial blocks (SA blocks) -- Sick Sinus Syndrome (SSS) -- Summary of key points -- Quiz -- Chapter 8: Miscellaneous cardiac conditions -- Background -- Paced rhythms -- Types of permanent pacemaker (PPM) -- ECG identification of Pacemakers -- Pericarditis -- Long QT syndromes -- Summary of key points -- Quiz -- Chapter 9: Non cardiac conditions identifiable on the ECG -- Background -- Electrolyte imbalances -- Hypothermia -- Digoxin use -- Pulmonary Embolism (PE) -- Summary of key points -- Quiz -- Chapter 10: Acute Coronary Syndromes -- Background -- Atherosclerosis -- Modifiable and non-modifiable risk factors for CHD -- Angina -- Acute Coronary Syndromes (ACS) -- Evolution of STEMI -- Left Bundle Branch Block (LBBB) and chest pain -- Summary of key points -- Quiz.
  • "All known local tobacco control ordinances in the US that have one or more of the following provisions--clean indoor air, youth access, or restrictions on tobacco advertising and promotion."
  • "Achieving equity in health requires a commitment to monitoring health inequalities which, in turn, necessitates strong, equity-oriented health information systems. High-quality data and robust monitoring systems ensure that efforts can be targeted appropriately and that progress can be tracked. Countries must strengthen health information systems to generate better data and evidence to measure progress. Integral to the health inequality monitoring process is the task of reporting data in a meaningful way. This State of inequality report exemplifies effective reporting practices, featuring the topic of reproductive, maternal, newborn and child health. The report addresses the challenge of how to best communicate a large and complex body of data in a manner that is comprehensible, flexible and appealing to a wide readership. Foreword viii Feature stories provide an in-depth look at the state of inequality for selected indicators and highlight key observations in reproductive health interventions, maternal health interventions, care-seeking for sick children, childhood immunization, child malnutrition and child mortality. Perhaps most notable, however, is the innovative use of electronic visualization technology. Story-point dashboards, for instance, guide the reader through a succession of visuals where readers can use interactive tools to further explore, sort and filter the data. Similarly, interactive maps and tables engage readers in customizing how data are viewed. The report reveals that significant inequalities exist in low- and middle-income countries in the area of reproductive, maternal, newborn and child health. The good health of women, infants and children is essential for sustainable development, and there is still much work to be done. Discussions will increasingly call into question how efforts to improve reproductive, maternal, newborn and child health can achieve early and accelerated progress among those who are falling behind."--Pages viii-ix
  • To serve as a tool to help community planning groups (CPGs), health departments, and other stakeholders understand the issues behind Latino participation in HIV prevention community planning, as well as to increase Latino participation in the process.
  • State of the air 2014. 2014
    American Lung Association
    The State of the Air 2014 report looks at levels of ozone and particle pollution found in official monitoring sites across the United States in 2010, 2011, and 2012. The report uses the most current quality-assured nationwide data available for these analyses.
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    State of the art analytical comparability: a review / A.J. Chirino, A.R. Mire-Sluis -- Validation of peptide mapping with electrospray mass spectrometry for recombinant proteins of biopharmaceutical interest and its applications as an identity test and a characterization tool / Z. Wei ... [et al.] -- Analysis of protein therapeutics by capillary electrophoresis: applications and challenges / S. Ma -- Mass spectrometry and HPLC for carbohydrate analysis / J. Siemiatkoski, Y. Lyubarskaya -- Using nuclear magnetic resonance spectroscopy to characterize biologicals / D.I. Freedberg -- Infrared and raman spectroscopy characterization of biological products / V. Reipa -- Characterization of an immune response / S.J. Swanson -- Evaluation of standard and state of the art analytical technology - bioassays / S.R. Indelicato ... [et al.] -- Heterogeneity of recombinant antibodies: linking structure to function / R.J. Harris -- Quality control system to support comparability assessment for the renal bio-replacement therapy system / Z. Pitkin -- Characterization of gene therapy products and the impact of manufacturing changes on product comparability / S.L. Simek -- Characterization of allergen extracts / J.E. Slater -- Detection, measurement and characterization of unwanted antibodies induced by therapeutic biologicals / M. Wadhwa ... [et al.] -- De-immunization of therapeutic proteins by T-cell epitope modification / A.S. de Groot, P.M. Knopf, W. Martin -- Strategies for the preclinical and clinical characterization of immunogenicity / E. Koren ... [et al.]
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  • Scientific method : the language of statistical studies -- Experimentation : the foundation of scientific studies -- Numbers good and bad : how to judge the quality of data -- Samples and surveys : how numbers should be collected -- Descriptive statistics : the foundation of comparisons -- Inferential statistics : studies of differences -- Relational statistics : studies of relationships -- Explanatory statistics : studies of causality.
  • The core principles of statistical analysis are too easily forgotten in today's world of powerful computers and time-saving algorithms. This step-by-step primer takes researchers who lack the confidence to conduct their own analyses right back to basics, allowing them to scrutinize their own data through a series of rapidly executed reckonings on a simple pocket calculator. A range of easily navigable tutorials facilitate the reader's assimilation of the techniques, while a separate chapter on next generation Flash prepares them for future developments in the field. This practical volume also contains tips on how to deny hackers access to Flash internet sites. An ideal companion to the author's co-authored works on statistical analysis for Springer such as Statistics Applied to Clinical Trials, this monograph will help researchers understand the processes involved in interpreting clinical data, as well as being a necessary prerequisite to mastering more advanced statistical techniques. The principles of statistical analysis are easily forgotten in today's world of time-saving algorithms. This step-by-step primer takes researchers back to basics, enabling them to examine their own data through a series of sums on a simple pocket calculator.
  • "Human growth refers to changes in anthropometric measurements, such as fetal size parameters, height, weight, and body mass index. Development refers to changes in cognitive, social-emotional, locomotor, and other abilities. This book illustrates how statistical methods can be used to answer research questions in human growth and development. In addition to describing methods, it looks at how well a method addresses a specific research question and how to interpret and present the analytic results. Although the examples are drawn from human growth and development, the concepts and methods are applicable to studies of many other physical and psychological phenomena, such as lung function and depressive symptoms. Requiring introductory statistics knowledge, the book is intended for clinical researchers, epidemiologists, social scientists, statisticians, related researchers, and post-graduate students investigating human growth and development"--Provided by publisher.
  • Statistical analysis with Excel for dummies 2005
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  • "The massive amount of nonstandard high-dimensional brain imaging data being generated is often difficult to analyze using current techniques. This challenge in brain image analysis requires new computational approaches and solutions. But none of the research papers or books in the field describe the quantitative techniques with detailed illustrations of actual imaging data and computer codes. Using MATLABʼ and case study data sets, Statistical and Computational Methods in Brain Image Analysis is the first book to explicitly explain how to perform statistical analysis on brain imaging data. The book focuses on methodological issues in analyzing structural brain imaging modalities such as MRI and DTI. Real imaging applications and examples elucidate the concepts and methods. In addition, most of the brain imaging data sets and MATLAB codes are available on the author's website. By supplying the data and codes, this book enables researchers to start their statistical analyses immediately. Also suitable for graduate students, it provides an understanding of the various statistical and computational methodologies used in the field as well as important and technically challenging topics."--Provided by publisher.
  • Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics link model -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response.
  • Introduction -- Two basic data mining methods for variable assessment -- CHAID-based data mining for paired-variable assessment -- The importance of straight data : simplicity and desirability for good model-building practice -- Symmetrizing ranked data : a statistical data mining method for improving the predictive power of data -- Principal component analysis : a statistical data mining method for many-variable assessment -- The correlation coefficient : its values range between plus/minus 1, or do they? -- Logistic regression : the workhorse of response modeling -- Ordinary regression : the workhorse of profit modeling -- Variable selection methods in regression : ignorable problem, notable solution -- CHAID for interpreting a logistic regression model -- The importance of the regression coefficient -- The average correlation : a statistical data mining measure for assessment of competing predictive models and the importance of the predictor variables -- CHAID for specifying a model with interaction variables -- Market segmentation classification modeling with logistic regression -- CHAID as a method for filling in missing values -- Identifying your best customers : descriptive, predictive, and look-alike profiling -- Assessment of marketing models -- Bootstrapping in marketing : a new approach for validating models -- Validating the logistic regression model : try bootstrapping -- Visualization of marketing modelsdata mining to uncover innards of a model -- The predictive contribution coefficient : a measure of predictive importance -- Regression modeling involves art, science, and poetry, too -- Genetic and statistic regression models : a comparison
  • Molecular genetics -- Formal genetics -- Genetic markers -- Data quality -- Genetic map distances -- Family studies -- Twin and adoption studies -- Model-based linkage analysis -- Model-free linkage analysis -- Quantitative traits -- Fundamental concepts of association analyses -- Association analysis in unrelated individuals -- Family-based association analysis -- Haplotypes in association analyses -- Genome-wide Association (GWA) studies.
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  • Introduction -- Accelerated testing -- Expiration dating period -- Stability designs -- Stability analysis with fixed batches -- Stability analysis with random batches -- Stability analysis with a mixed effects model -- Stability analysis with discrete responses -- Stability analysis with multiple components -- Stability analysis with frozen drug products -- Stability testing for dissolution -- Current issues and recent development.
  • Chapter 1 -- Background and Introduction; Chapter 2 -- Diagnostic Rating Scales; Chapter 3 -- Monotone Transformation Models; Chapter 4 -- Combination and Pooling of Biomarkers; Chapter 5 -- Bayesian ROC Methods; Chapter 6 -- Sequential Designs of ROC Experiments; Chapter 7 -- Multireader ROC Analysis; Chapter 8 -- Free-Response ROC Analysis; Chapter 9 -- Machine Learning and Predictive Modeling; Chapter 10 -- Summary and Challenges; Appendix: Notation List; Back Cover.
  • Apples or oranges? -- selection of the control group -- Who was left out? exclusions, refusals, and drop-outs -- Mountain or molehill? the clinical importance of the results -- What do the other witnesses say? corroborating vidence -- Do the pieces fit together? systematic overviews and meta-analysis -- What do all these numbers mean? -- Where is the evidence? searching for information.
  • "Data analysis is changing fast. Driven by a vast range of application domains and affordable tools, machine learning has become mainstream. Unsupervised data analysis, including cluster analysis, factor analysis, and low dimensionality mapping methods continually being updated, have reached new heights of achievement in the incredibly rich data world that we inhabit.Statistical Learning and Data Science is a work of reference in the rapidly evolving context of converging methodologies. It gathers contributions from some of the foundational thinkers in the different fields of data analysis to the major theoretical results in the domain. On the methodological front, the volume includes conformal prediction and frameworks for assessing confidence in outputs, together with attendant risk. It illustrates a wide range of applications, including semantics, credit risk, energy production, genomics, and ecology. The book also addresses issues of origin and evolutions in the unsupervised data analysis arena, and presents some approaches for time series, symbolic data, and functional data. Over the history of multidimensional data analysis, more and more complex data have become available for processing. Supervised machine learning, semi-supervised analysis approaches, and unsupervised data analysis, provide great capability for addressing the digital data deluge. Exploring the foundations and recent breakthroughs in the field, Statistical Learning and Data Science demonstrates how data analysis can improve personal and collective health and the well-being of our social, business, and physical environments. "-- Provided by publisher.
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    Discriminant analysis based on continuous and discrete variables -- Longitudinal data analysis with linear regression -- A kernal method used for the analysis of replicated micro-array experiments -- Kernel estimates of hazard functions for biomedical data sets -- Partially linear models -- Analysis of contingency tables -- Identifying coexpressed genes -- Bootstrap methods for testing interactions in GAMs -- Survival trees -- A semiparametric reference curves estimation -- Survival analysis -- Ozone pollution forecasting -- Nonparametric functional chemometric analysis -- Variable selection in principal component analysis -- Spatial statistics -- Functional data analysis -- Analysis of failure time with microearthquakes applications -- Landcover prediction -- The application of fuzzy clustering to satellite images data.
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  • Introduction / Jana Asher -- The statistics of genocide / Mary W. Gray and Sharon Marek -- Why estimate direct and indirect casualties from war? The rule of proportionality and casualty estimates / Beth O. Daponte -- Statistical thinking and data analysis : enhancing human rights work / Jorge L. Romeu -- Hidden in plain sight : X.X. burials and the desaparecidos in the Department of Guatemala, 1977-1986 / Clyde Collins Snow, Fredy Armando Peccerelli, José Samuel Susanávar, Alan G. Robinson, and Jose Maria Najera Ochoa -- The demography of conflict-related mortality in Timor-Leste (1974-1999) : reflections on empirical quantitative measurement of civilian killings, disappearances, and famine-related deaths / Romesh Silva and Patrick Ball -- Afghan refugee camp surveys in Pakistan, 2002 / James Bell, David Nolle, Ruth Citrin and Fritz Scheuren -- Metagora : an experiment in the measurement of democratic governance / Jan Robert Suesser and R. Suarez de Miguel -- Human rights of statisticians and statistics of human rights : early history of the American Statistical Association's Committee on Scientific Freedom and Human Rights / Thomas B. Jabine and Douglas A. Samuelson -- Obtaining evidence for the International Criminal Court using data and quantitative analysis / Herbert F. Spirer and William Seltzer -- New issues in human rights statistics / David L. Banks and Yasmin H. Said -- Statistics and the Millennium Development Goals / David J. Fitch, Paul Wassenich, Paul Fields, Fritz Scheuren, and Jana Asher -- Using population data systems to target vulnerable population subgroups and individuals : issues and incidents / William Seltzer and Margo Anderson.
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  • Univariate Data -- Bi- and Multivariate Data -- Related Topics -- Complex Examples -- Appendices.
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  • Part I. Basic statistics -- 1. Experimental statistics for biological sciences / Heejung Bang and Marie Davidian -- 2. Nonparametric methods for molecular biology / Knut M. Wittkowski and Tingting Song -- 3. Basics of Bayesian methods / Sujit K. Ghosh -- 4. The Bayesian t-test and beyond / Mithat Gönen -- -- Part II. Designs and methods for molecular biology -- 5. Sample size and power calculation for molecular biology studies / Sin-Ho Jung -- 6. Designs for linkage analysis and association studies of complex diseases / Yuehua Cui ... [et al.] -- 7. Introduction to epigenomics and epigenome-wide analysis / Melissa J. Fazzari and John M. Greally -- 8. Exploration, visualization, and preprocessing of high-dimensional data / Zhijin Wu and Zhiqiang Wu -- -- Part III . Statistical methods for microarray data -- 9. Introduction to the statistical analysis of two-color microarray data / Martina Bremer, Edward Himelblau, and Andreas Madlung -- 10. Building networks with microarray data / Bradley M. Broom ... [et al.] -- Part IV. Advanced or specialized methods for molecular biology -- 11. Support vector machines for classification: a statistical portrait / Yoonkyung Lee -- 12. An overview of clustering applied to molecular biology / Rebecca Nugent and Marina Meila -- 13. Hidden Markov model and its applications in motif findings / Jing Wu and Jun Xie -- 14. Dimension reduction for high-dimensional data / Lexin Li -- 15. Introduction to the development and validation of predictive biomarker models from high-throughput data sets / Xutao Deng and Fabien Campagne -- 16. Multi-gene expression-based statistical approaches to predicting -- patients' clinical outcomes and responses / Feng Cheng, Sang-Hoon Cho, and Jae K. Lee -- 17. Two-stage testing strategies for genome-wide association studies in family-based designs / Amy Murphy, Scott T. Weiss, and Christoph Lange -- 18. Statistical methods for proteomics / Klaus Jung -- -- Part V. Meta-analysis for high-dimensional data -- 19. Statistical methods for integrating multiple types of high-throughput data / Yang Xie and Chul Ahn -- 20. A Bayesian hierarchical model for high-dimensional meta-analysis / Fei Liu -- 21. Methods for combining multiple genome-wide linkage studies / Trecia A. Kippola and Stephanie A. Santorico -- -- Part VI. Other practical information -- 22. Improved reporting of statistical design and analysis: guidelines, education, and editorial policies / Madhu Mazumdar, Samprit Banerjee, and Heather L. Van Epps -- 23. Stata companion / Jennifer Sousa Brennan.
  • Markov models in molecular evolution / Nicolas Galtier, Olivier Gascuel, and Alain Jean-Marie -- Introduction to applications of the likelihood function in molecular evolution / Jutta Buschbom and Arndt von Haeseler -- Introduction to Markov chain Monte Carlo methods in molecular evolution / Bret Larget -- Population genetics of molecular evolution / Carlos D. Bustamante -- Maximum likelilhood methods for detecting adaptive protein evolution / Joseph P. Bielawski and Ziheng Yang -- HyPhy: hypothesis testing using phylogenies / Sergei L. Kosakovsky Pond and Spencer V. Muse -- Bayesian analysis of molecular evolution using MrBayes / John P. Huelsenbeck and Fredrik Ronquist -- Estimation of divergence times from molecular sequence data / Jeffrey L. Thorne and Hirohisa Kishino -- Markov models of protein sequence evolution / Matthew W. Dimmic -- Models of microsatellite evolution / Peter Calabrese and Raazesh Sainudiin -- Genome rearrangement / Rick Durrett -- Phylogenetic hidden Markov models / Adam Siepel and David Haussler -- The evolutionary causes and consequences of base composition variation / Gilean A.T. McVean -- Statistical alignment: recent progress, new applications, and challenges / Gerton Lunter ... [et al.] -- Estimating substitution matrices / Von Bing Yap and Terry Speed -- Posterior mapping and posterior predictive distributions / Jonathan P. Bollback -- Assessing the uncertainty in phylogenetic inference / Hidetoshi Shimodaira and Masami Hasegawa.
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    Simple linear regression -- Multiple linear regression -- Simple logistic regression -- Multiple logistic regression -- Introduction to survival analysis -- Hazard regression analysis -- Introduction to poisson regression : inferences on morbidity and mortality rates -- Multiple poisson regression -- Fixed effects analysis of variance -- Repeated-measures analysis of variance.
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    Let's get started: preliminaries and a SAS quick start -- Reading, combining, and managing data for later analysis -- Using SAS procedures -- Complex table construction and output control -- Basic models in SAS -- Producing statistical graphics in SAS -- Traditional SAS graphics -- Formatting variables, recoding variables, and writing programs -- Programming in a DATA step -- Macro programming -- Programming with matrices and vectors.
  • "While biomedical researchers may be able to follow instructions in the manuals accompanying the statistical software packages, they do not always have sufficient knowledge to choose the appropriate statistical methods and correctly interpret their results. Statistical Thinking in Epidemiology examines common methodological and statistical problems in the use of correlation and regression in medical and epidemiological research: mathematical coupling, regression to the mean, collinearity, the reversal paradox, and statistical interaction. Statistical Thinking in Epidemiology is about thinking statistically when looking at problems in epidemiology. The authors focus on several methods and look at them in detail: specific examples in epidemiology illustrate how different model specifications can imply different causal relationships amongst variables, and model interpretation is undertaken with appropriate consideration of the context of implicit or explicit causal relationships. This book is intended for applied statisticians and epidemiologists, but can also be very useful for clinical and applied health researchers who want to have a better understanding of statistical thinking. Throughout the book, statistical software packages R and Stata are used for general statistical modeling, and Amos and Mplus are used for structural equation modeling"--Provided by publisher.
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    Data display and summary -- Summary statistics for quantitative data -- Summary statistics for binary data -- Populations and samples -- Statements of probability and confidence intervals -- P-values, power, type I and type II errors -- The t tests -- The [chi]² tests -- Diagnostic tests -- Rank score tests -- Correlation and regression -- Survival analysis -- Study design and choosing a statistical test -- Use of computer software.
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  • Statistics in a nutshell 2008
    ProQuest Safari
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    v.1. Basic concepts and applications ; v.2 Advanced concepts and applications.
  • Planning studies: from design to publication -- Planning analysis: what do I do with my data? -- Probability and relative frequency -- Distribution -- Descriptive statistics -- Finding probabilities -- Confidence intervals -- Hypothesis testing: concept and practice -- Tests on categorical data -- Risks, odds, and ROC curves -- Tests on ranked data -- Tests on means of continuous data -- Multi-factor ANOVA and ANCOVA -- Tests on variability and distributions -- Managing results of analysis -- Equivalence testing -- Bayesian statistics -- Sample size estimation and meta-analysis -- Modeling concepts and methods -- Clinical decisions based on models -- Regression and correlation -- Multiple and curvilinear regression -- Survival, logistic regression, and cox regression -- Sequential analysis and time series -- Epidemiology -- Measuring association and agreement -- Questionnaires and surveys -- Methods you might meet, but not every day.
  • "Statistical investigation into technology not only provides a better understanding of the intrinsic features of the technology (analysis), but also leads to an improved design of the technology (synthesis). Physical principles and mathematical procedures of medical imaging technologies have been extensively studied during past decades. However, less work has been done on their statistical aspect. Filling this gap, this book provides a theoretical framework for statistical investigation into medical technologies. Rather than offer detailed descriptions of statistics of basic imaging protocols of x-ray CT and MRI, the book presents a method to conduct similar statistical investigations into more complicated imaging protocols"--Provided by publisher.
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    Introduction -- Examining univariate distributions -- Measures of location, spread, and skewness -- Re-expressing variables -- Exploring relationships between two variables -- Simple linear regression -- Probability fundamentals -- Theoretical probability models -- The role of sampling in inferential statistics -- Inferences involving the mean of a single population when s is known -- Inferences involving the mean when s is not known: one- and two-sample designs -- One-way analysis of variance -- Two-way analysis of variance -- Correlation and simple regression as inferential techniques -- An introduction to multiple regression -- Nonparametric methods.
  • History of status epilepticus / Peter W. Kaplan -- Types of status epilepticus: definitions and classification / Frank W. Drislane -- Differential diagnosis of status epilepticus; pseudostatus epilepticus / Barbara A. Dworetzky, Edward B. Bromfield -- The epidemiology of status epilepticus / Elizabeth J. Waterhouse -- The electroencephalogram in status epilepticus / Susan T. Herman -- Generalized convulsive status epilepticus: causes, systemic manifestations, and consequences / Bernard S. Chang -- Focal status epilepticus / Donald L. Schomer -- The Cellular physiology of status epilepticus / Omotola Hope, Hal Blumenfeld -- Cellular damage and the neuropathology of status epilepticus / Nathan B. Fountain -- Clinical presentations of nonconvulsive status epilepticus / Peter W. Kaplan -- Cognitive manifestations of status epilepticus: ictal aphasia, amnesia, and psychosis / Michael Benatar -- Nonconvulsive status epilepticus: morbidity and consequences / Frank W. Drislane -- Treatment of generalized convulsive status epilepticus / Tina Shih, Carl W. Bazil -- Treatment of refractory status epilepticus / Teresa L. Smith, Thomas P. Bleck -- Treatment of nonconvulsive status epilepticus / Frank W. Drislane -- Status epilepticus in children / James J. Riviello, Jr. -- Status epilepticus in neonates / John N. Gaitanis, James J. Riviello, Jr.
  • This report provides data on women's health status in the United States, beginning with a composite index of women's health that includes nine indicators covering chronic disease, sexual health, mental health, and physical health. It analyzes data on additional aspects of women's health, including behavioral measures such as smoking, exercise, and diet, and preventive health care measures such as mammograms, pap tests, and screenings for HIV. In addition, the report examines how women's health status has improved or declined in these areas in recent years. It also notes places where women's health status varies by race/ethnicity and age and examines the health status of those who identify as a sexual minority .
  • Obesity and diabetes develop as a complex result of genetic, metabolic and environmental factors and are characterized by increased lipogenesis and lipid accumulation in many tissues. Stearoyl-CoA desaturase (SCD) genes are a critical regulator of lipogenesis and catalyzes the synthesis of monounsaturated fatty acids (MUFA), mainly oleoyl- (18:1n9) and palmitoleoyl-CoA (16:1n7). These MUFAs are the major fatty acid substrates for the synthesis of triglycerides, cholesterol esters, wax esters and membrane phospholipids. There are 4 SCD isoforms (SCD1-4) in mice and two (hSCD1 and hSCD5) expressed in humans. At first glance, stearoyl-CoA desaturase enzyme would be considered a housekeeping enzyme because it synthesizes oleate a well-known fatty acid that is abundant in many dietary sources. However numerous studies have shown that SCD is a very highly regulated enzyme that features in so many physiological processes ranging from fat differentiation, carbohydrate and fat metabolism, inflammation and cancer. The editor's studies using stearoyl-CoA desaturase knockout (SCD1-/- ) mice and studies of other investigators using pharmacological approaches to reduce SCD1 expression in mouse tissues have all established that the expression of SCD1 gene isoform represents a key step in partitioning of lipids between storage and oxidation. High SCD expression favors fat storage leading to obesity while reduced SCD expression favors fat burning and leanness. Although these studies clearly illustrated that SCD1 expression is involved in the development of obesity and insulin resistance, questions remain in the elucidation of the mechanisms involved and role of SCD1. This book includes chapters by leading researchers on SCD Genes in the brain, heart, muscle, liver metabolism, Colitis, and more.
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  • Stedman's Medical dictionary 2006
    STAT!Ref, Limited to 7 simultaneous users
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    Anatomical illustrations -- Culture media -- Stains, dyes, and fixatives -- Greek alphabet -- Elements and symbols -- Units of measure for pathology -- Sample immunodiagnostic panels -- Common lab tests -- Drugs of abuse, toxicology, and therapeutic drug levels -- Sample reports -- Common terms by procedure --Classification by system including grades & stages.
  • Heart -- Neuro -- Musculoskeletal -- Kidney -- Eye -- Pancreas -- Hematology -- Skin.
  • Stem cell assays 2007
    Springer Protocols
    Derivation of human embryonic stem cells in xeno-free conditions / Mohan C. Vemuri ... [et al.] -- Feeder-layer free culture system for human embryonic stem cells / Michal Amit -- Digital imaging of stem cells by electron microscopy / A. Henry Sathananthan and Stefania A. Nottola -- A controlled-cooling protocol for cryopreservation of human and non-human primate embryonic stem cells / Carol B. Ware and Szczepan W. Baran -- Cell surface markers in human embryonic stem cells / Raj R. Rao, Alison Venable Johnson, and Steven L. Stice -- Generation of a monoclonal antibody library against human embryonic stem cells / Micha Drukker, Christina Muscat, and Irving L. Weissman -- Analytical methods for cancer stem cells / Vinagolu K. Rajasekhar -- Micro RNA profiling : an easy and rapid method to screen and characterize stem cell populations / Uma Lakshmipathy ... [et al.] -- Gene transfer via nucleofection into adult and embryonic stem cells / Uma Lakshmipathy, Shannon Buckley, and Catherine Verfaillie -- RNAi knockdown of transcription factor Pu.1 in the differentiation of mouse embryonic stem cells / Gang-Ming Zou, Meredith A. Thompson, and Mervin C. Yoder -- StemBase : a resource for the analysis of stem cell gene expression data / Christopher J. Porter ... [et al.] -- Isolation of stem cells from human umbilical cord blood / Nishanth P. Reddy, Mohan C. Vemuri, and Reddanna Pallu -- Ex vivo expansion of hematopoietic stem cells from human cord blood in serum-free conditions / Chao-Ling Yao and Shiaw-Min Hwang -- Hematopoietic colony-forming cell assays / Carla Pereira, Emer Clarke, and Jackie Damen -- Assays for alloreactive responses by PCR / Patrick Stordeur -- Immune properties of mesenchymal stem cells / Panagiota A. Sotiropoulou and Michael Papamichail -- Clinical grade expansion of human bone marrow mesenchymal stem cells / Panagiota A. Sotiropoulou, Sonia A. Perez, and Michael Papamichail -- Adenoviral transduction of mesenchymal stem cells / Pablo Bosch and Steven L. Stice -- Directed differentiation of human embryonic stem cells to dendritic cells / Maxim A. Vodyanik and Igor I. Sluvkin -- Insulin-producing cells from embryonic stem cells to dendritic cells / Maxim A. Vodyanik and Igor I. Slukvin -- Insulin-producing cells from embryonic stem cells experimental considerations / Enrique Roche ... [et al.] -- Efficient generation of dopamine neurons from human embryonic stem cells / Chang-Hwan Park and Sang-Hun Lee -- Isolation of oligodendroglial cells from cultured neural stem/progenitors / Frank Zeigler and Stephen G. Hall -- Differentiation of human embryonic stem cells toward the chondrogenic lineage / Wei Seong Toh ... [et al.] -- Cartilage tissue engineering : directed differentiation of embryonic stem cells in three-dimensional hydrogel culture / Nathaniel S. Hwang, Shyni Varghese, and Jennifer Elisseeff.
  • Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modeling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.
  • Part 1. Bone marrow-derived stem cells -- Part 2. Embryonic stem cells -- Part 3. Cancer stem cells.
  • "This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control"--Publisher's description.
  • Stem cell culture 2008
  • "Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward"--Provided by publisher.
  • Immunostaining of germline stem cells and the niche in Drosophila ovaries / Lichao Luo, Phing Chian Chai, and Yu Cai -- Genetic, immunofluorescence labeling, and in situ hybridization techniques in identification of stem cells in male and female germline niches / Shree Ram Singh ... [et al.] -- Visualization of adult stem cells within their niches using the Drosophila germline as a model system / Annekatrin König and Halyna R. Shcherbata -- Morphometric evaluation of the spermatogonial stem cell distribution and niche in vertebrates / Paulo Henrique Almeida Campos-Junior ... [et al.] -- In vitro construction of 2D and 3D simulations of the murine hematopoietic niche / Brahmananda Reddy Chitteti ... [et al.] -- Isolation of embryonic hematopoietic niche cells by flow cytometry and laser capture microdissection / Daisuke Sugiyama and Tatsuya Sasaki -- Isolation and enrichment of Stro-1 immunoselected mesenchymal stem cells from adult human bone marrow / Emma L. Williams, Kate White, and Richard O.C. Oreffo -- Primary marrow-derived stromal cells : isolation and manipulation / Aravind Ramakrishnan, Beverly Torok-Storb, and Manoj M. Pillai -- Detection in vitro and quantitative estimation of artificial microterritories which promote osteogenic differentiation and maturation of stromal stem cells / Igor A. Khlusov, Natalya M. Shevtsova, and Marina Yu. Khlusova -- Prospective isolation of viable, high ploidy megakaryocytes from adult murine bone marrow by fluorescence activated cell sorting / Shen Y. Heazlewood ... [et al.] -- Looking for the niche : substance delivery into the lateral ventricle of the brain : the osmotic minipump system / María Victoria Gómez Gaviro ... [et al.] -- Unbiased stereological method to assess proliferation throughout the subependymal zone / Ana Mendanha Falcão ... [et al.] -- Cardiac stem cell niche, MMP9, and culture and differentiation of embryonic stem cells / Paras Kumar Mishra ... [et al.] -- Human and murine skeletal muscle reserve cells / Rana Abou-Khalil, Fabien Le Grand, and Bénédicte Chazaud -- Modulation of the host skeletal muscle niche for donor satellite cell grafting / Luisa Boldrin and Jennifer E. Morgan -- Isolation of c-Kit+ human amniotic fluid stem cells from second trimester / Michela Pozzobon ... [et al.] -- Hypoxia and visualization of the stem cell niche / Ali Dalloul -- Detection and isolation of human disseminated tumor cells in the murine bone marrow stem cell niche / Yusuke Shiozawa, Russell S. Taichman, and Evan T. Keller -- Identification and separation of normal hematopoietic stem cells and leukemia stem cells from patients with acute myeloid leukemia / Van T. Hoang ... [et al.] -- Serial orthotopic transplantation of epithelial tumors in single-cell suspension / Heather A. McCauley and Géraldine Guasch -- Isolation and propagation of colon cancer stem cells / Pramudita R. Prasetyanti ... [et al.].
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    Foreword by Donald Kennedy -- Abbreviations -- The experiment that shook the world -- The cell -- How we get to how we are -- A brief history of embryonic stem cells -- Hunting adult stem cells -- Seven questions -- The future of medicine -- The great moral divide -- The consequences of politics -- Epilogue -- Notes -- Glossary -- Further reading -- Acknowledgments.
  • Ventricular remodeling in ischemic cardiomyopathy / Stefan Klotz and Daniel Burkhoff -- Myocardial regeneration: which cell and why / Elmostafa El Fahime and Jacques Tremblay -- Cardiac stem cells for myocardial regeneration / Bernardo Nadal-Ginard and Simón Méndez-Ferrer -- A historic recapitulation of myoblast transplantation / Daniel Skuk and Jacques Tremblay -- Myoblast cell transplantation preclinical studies / Doris A. Taylor and Harald Ott -- Skeletal myoblasts: the European experience / Philippe Menasche -- Skeletal myoblasts: the U. S. experience / Edward B. Diethrich -- Progenitor cells for cardiac regeneration / Ana Sánchez and Javier Garcia-Sancho -- Bone marrow derived stem cell for myocardial regeneration: preclinical experience / Bradley Martin and Mark Pittenger -- Bone marrow derived stem cell for myocardial regeneration: clinical experience, surgical delivery / Manual Galiñanes -- Autologous mononuclear bone marrow cell transplantation for myocardial infarction: the German experience / Michael Brehm, Tobias Zeus and Bodo E. Strauer -- Autologous mononuclear bone marrow cell transplantation for myocardial infarction: the Spanish experience / Francisco E. Avilés ... [et al.] -- Mobilizing bone marrow stem cells for myocardial repair after acute myocardial infarction / Steve Ellis and Oussama Wazni -- Percutaneous myoblast transplantation: steps in transplantation research / Nabil Dib -- A porcine model of myocardial infarction for evaluation of cell transplantation / Nabil Dib ... [et al.] -- Tissue engineering for myocardial regeneration / Ravi K. Birla -- The role of pet scan in stem cell therapy / Uchechukwa Sampson ... [et al.] -- The measurement of systolic function in the mammalian heart / Blasé Carabello -- Electrophysiological aspects of cell transplantation / Nicholas S. Peters, Nicolas A.F. Chronos and Fernando Tondato -- Regulatory considerations in manufacturing, product testing, and preclinical development of cellular products for cardiac repair / Ellen Areman, Kim Benton and Richard McFarland.
  • 1. Lysosomal diseases and therapeutic options: an overview / Eveline J. Langereis and Frits A. Wijburg -- 2. Alternative treatment options: enzyme replacement and small molecule therapies / James Edmond Wraith and Simon Jones -- 3. Hematopoietic cell transplantation in inborn errors of metabolism / Jaap J. Boelens, Paul Szaboles, and Rob Wynn -- 4. Leukodystrophies and lysosomal storage disorders / Maria L. Escolar and Mieke Aldenhoven -- 5. Hematopoietic stem cell gene therapy for lysosomal storage disorders: expected benefits and limitations / Alessandra Biffi and Ilaria Visigalli -- 6. Alternative future therapies for lysosomal storage diseases: embryonic stem cell- and induced pluripotent stem cell therapy / Arie Koen Braat, Paul J. Coffer, and Niels Geijsen -- 7. Concluding comments and future directions / Robert Wynn and Jaap Jan Boelens.
  • In vitro experimentation and research tools -- Tissue engineering and regenerative medicine.
  • Section I. Basic Aspects of Transplantation -- The Frontiers of Organ Transplantation and Cell Therapy / Rafael Matesanz -- Organ Transplantation in the 21th Century / Francisco Ortega -- Immunology and the Challenge of Transplantation / Rebeca Alonso Arias, Antonio López-Vázquez and Carlos López-Larrea -- Cellular Immunotolerance in the Transplant / Marcos Lóez-Hoyos, David San Segundo and Manuel Arias -- Immunosuppression in the ERA of Biological Agents / Josep M. Grinyó, Josep M. Cruzado, Oriol Bestard, J. R. Vidal Castiñeira and Joan Torras -- Transgenic Organs and Xenotransplants / Cristina Costa Vallés and Rafael Máñez Mendiluce -- Cell and Tissue Therapy in Regenerative Medicine / Ana Sánchez, Thomas Schimmang and Javier García-Sancho -- Section II. Adult Stem Cells -- Characteristics of Adult Stem Cells / Manuel A. Gonzalez and Antonio Bernad -- Bone Marrow Transplantation Extends Its Scope / Fermín M. Sánchez-Guijo, Alberto Orfao and María Consuelo del Cañizo -- Biology of Stem Cells: The Role of Microenvironments / Agustín G. Zapata, David Alfaro and Javier García-Ceca -- Mobilization and Homing of Hematopoietic Stem Cells / Beatriz Suárez-Álvarez, Antonio López-Vázquez and Carlos López-Larrea -- Great Promise of Tissue-Resident Adult Stem/Progenitor Cells in Transplantation and Cancer Therapies / Murielle Mimeault and Surinder K. Batra -- Multipotent Mesenchymal Stromal Cells: Clinical Applications and Cancer Modeling / René Rodríguez, Javier García-Castro, Cesar Trigueros, Mariano García Arranz and Pablo Menéndez -- Section III. Embryonic Stem Cells -- Neural Stem Cells and Transplantation Studies in Parkinson's Disease / Ricardo Pardal and José López-Barneo -- Biological Impact of Human Embryonic Stem Cells / Miguel Martín and Pablo Menéndez -- Epigenetics of Embryonic Stem Cells / Vincenzo Calvanese and Mario F. Fraga -- New Tools in Regenerative Medicine: Gene Therapy / Miguel Muñoz Ruiz and José R. Regueiro -- Therapeutic Cloning and Cellular Reprogramming / Ramon M. Rodriguez, Pablo J. Ross and Jose B. Cibelli -- Section IV. Stem Cell Regenerative Medicine -- Advances in Stem Cell Therapy / Silvia Pérez López and Jesús Otero Hernández -- Tissue Bioengineering and Artificial Organs / Sara Llames, Eva García, Jesús Otero Hernández and Álvaro Meana.
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    Clinical potentials of stem cells: hype or hope? -- Alteration of hematopoietic stem cell fates by chromatin-modifying agents -- Increasing impact of micro RNAs in stem cell biology and medicine -- Novel strategies for the mobilization of hematopoietic stem cell -- Pluripotent stem cells from umbilical cord blood -- Good manufacturing practices: clinical-scale production of mesenchymal stem cells -- The clonal activity of marked hematopoietic stem cell -- A large animal non-injury model for study of human stem cell plasticity -- Developmental potential of somatic stem cells following injection into murine blastocysts -- Testing the limits: the potential of MAPC in animal models -- Mesenchymal stem cells as vehicles for genetic targeting of tumors -- Endothelial progenitor cells for cardiac regeneration -- Stem cells and bypass grafting for myocardial and vascular regeneration -- Adoptive immunotherapy: guidelines and clinical practice -- Immune escape and suppression by human mesenchymal stem cells -- Stem cell transplantation: the basis for successful cellular immunotherapy.
  • Chapter 1. Promises and Limitations in the Application of Cell Therapy for Tissue Regeneration / Raphael Gorodetsky -- Chapter 2. Adult Non-hematopoietic Stem Cells and Progenitor Cells (aNHSCs) / R. Schäfer and L. Dahéron -- Chapter 3. Screening Approaches for Stem Cells / David G. Buschke, Derek J. Hei, Kevin W. Eliceiri and Brenda M. Ogle -- Chapter 4. Hematopoietic Stem Cells and their Role in Regenerative Medicine / Eitan Fibach -- Chapter 5. Cord and Cord Blood: Valuable Resources with Potential for Liver Therapy / Saba Habibollah, Marcin Jurga, Nico Forraz and Colin McGuckin -- Chapter 6. Induced Pluripotent Stem Cells: Their Role in Modeling Disease and Regenerative Medicine / Yonatan Stelzer and Marjorie Pick -- Chapter 7. Mesenchymal Stromal/Stem Cells from Tissue Repair to Destruction of Tumor Cells / Rita Bussolari, Giulia Grisendi, Luigi Cafarelli, Pietro Loschi, Laura Scarabelli, Antonio Frassoldati, Michela Maur, Giorgio De Santis, Paolo Paolucci, Pierfranco Conte and Massimo Dominici -- Chapter 8. Fibrin-based Matrices to Support Stem Cell-Based Tissue Regeneration / Raphael Gorodetsky, Iris Mironi-Harpaz and Dror Seliktar -- Chapter 9. Culturing Non-hematopoietic Mesenchymal Stromal Cells and Requirements of GMP in Stem Cell-based Therapies / Karen Bieback, Marianna Karagianni, Gerlinde Schmidtke-Schrezenmeier, Natalie Fekete and Hubert Schrezenmeier -- Chapter 10. (Stem) Cell Based Therapy for Neurological Disorders / O. Einstein and T. Ben-Hur -- Chapter 11. Mesenchymal Osteogenic Precursors for Bone Repair and Regeneration / Nicola Baldini, Dante Dallari and Francesca Perut -- Chapter 12. Stem Cells and Cartilage Repair / Bernd Rolauffs, Andreas Badke, Kuno Weise, Alan J. Grodzinsky and Wilhelm K. Aicher -- Chapter 13. Stem Cell-based Replacement Tissue for Heart Repair / Ayelet Lesman and Shulamit Levenberg -- Chapter 14. Regeneration of the Vascular System / M. Schleicher, A. J. Huber, H. P. Wendel and U. A. Stock -- Chapter 15. Regenerative Strategies for the Endocrine Pancreas: From Islets to Stem Cells and Tissue Reprogramming / Juan Domínguez-Bendala and Camillo Ricordi -- Chapter 16. Regeneration of the Lower Urinary Tract: Clinical Applications and Future Outlook / Markus Renninger, Bastian Amend, Jörg Seibold, Gerhard Feil, Arnulf Stenzl and Karl-Dietrich Sievert -- Chapter 17. Effective Tissue Repair and Immunomodulation by Mesenchymal Stem Cells within a Milieu of Cytokines / Philip Lim, Shyam A. Patel and Pranela Rameshwar -- Chapter 18. Homing of Mesenchymal Stromal Cells / Reinhard Henschler, Erika Deak and Richard Schäfer.
  • Stem cells 2006
  • pt. 1. Stem cell biology -- pt. 2. Epigenetic and microRNA regulation in stem cells -- pt. 3. Stem cells for therapeutic applications -- pt. 4. Nuclear reprogramming and induced pluripotent stem cells -- pt. 5. Tissue engineering -- pt. 6. Regenerative medicine.
  • Use of Human Embryonic Stem Cells in Therapy -- Human Neural Stem Cell-based Cell- and Gene-therapy for Neurological Diseases -- Vascular Stem Cell Therapy -- Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications -- Blood Cell Bioprocessing: The Haematopoietic System and Current Status of In-vitro Production of Red Blood Cells -- Bioprocessing Challenges Associated with the Purification of Cellular Therapies -- Separation Technologies for Stem Cell Bioprocessing.
  • The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.
  • The challenge for stem cell therapy: overview of the problem: heart attack and heart failure -- Hematopoietic stem cells for myocardial regeneration -- Mesenchymal stem cells for cardiac therapy -- Multipotent adult progenitor cells -- Mesenchymal progenitor cells for vascular formation and cardiac muscle regeneration -- Umbilical cord blood stem cells for myocardial regeneration and angiogenesis -- Endogenous cardiac stem cells -- Embryonic stem cells for myocardial repair -- Chemokin and homing factor expression in acute myocardial infarction and chronic heart failure -- Stem cell differentiation toward a cardiac myocyte phenotype -- Electrical coupling and/or ventricular tachycardia risk of cell therapy -- Cell therapy for myocardial damage: arrhythmia risk and mechanisms -- Aspects of percutaneous cellular cardiomyoplasty -- Stem cells and myocardial regeneration: open-chest/minimally invasive surgical techniques -- Measures of effective cell based therapies -- Whole bone marrow transplantation -- Clinical angioblast therapy -- Use of skeletal myoblasts for the treatment of chronic heart failure -- Bone marrow and angioblast transplantation -- Strategies for cytokine modification and stem cell mobilization for acute myocardial infarction -- 21 summary and future challenges.
  • pt. 1. Defining, isolating, and characterizing various stem and progenitor cell populations for neovascularization -- pt. 2. In vitro studies for angiogenesis, vasculogenesis, and arteriogenesis -- pt. 3. Stem cell mobilization strategies -- pt. 4. Stem cell transplantation strategies.
  • Stem cells for myocardial repair and regeneration : where are we today? / Randall J. Lee -- Bone marrow-derived endothelial progenitor cells : isolation and characterization for myocardial repair / Masaaki Ii -- Umbilical cells stem cells for myocardial repair and regeneration / Nicholas Greco and Mary J. Laughlin -- Isolation of resident cardiac progenitor cells by Hoechst 33342 staining / Otmar Pfister ... [et al.] -- Mesenchymal stem cell therapy for cardiac repair / Andrew J. Boyle, Ian K. McNiece, and Joshua M. Hare -- Methods for human embryonic stem cells derived cardiomyocytes cultivation, genetic manipulation, and transplantation / Gil Arbel ... [et al.] -- Experimental cell transplantation therapy in rat myocardial infarction model including nude rat preparation / Wangde Dai and Robert A. Kloner -- Large animal model of heart failure for assessment of stem cells / Sharad Rastogi -- Histopathologic assessment of myocardial regeneration / Naima Carter-Monroe ... [et al.] -- Assessment of myocardial angiogenesis and vascularity in small animal models / Matthew L. Springer -- Superparamagnetic iron oxide labeling of stem cells for MRi tracking and delivery in cardiovascular disease / Dorota A. Kedziorek and Dara L. Kraitchman -- Embryonic stem cell biology : insights from molecular imaging / Karim Sallam and Joseph C. Wu -- Genetic fate-mapping for studying adult cardiomyocyte replenishment after myocardial injury / Sunny S.-K. Chan ... [et al.] -- In vitro electrophysiological mapping of stem cells / Seth Weinberg, Elizabeth A. Lipke, and Leslie Tung -- Assessment of cardiac conduction : basic principles of optical mapping / Chunhua Ding and Thomas H. Everett IV -- Surface patterning for generating defined nanoscale matrices / Karen L. Christman and Heather D. Maynard.
  • Stem Cells Handbook, second edition, emphasizesthe advances in understanding and working with embryonic and fetal stem cells as well as induced pluripotent stem cells that show the most promise for clinical use. This new edition has been completely rewritten and updated to reflect the significant advances made in this field since publication of the first edition in 2004. The thirty-six chapters in this book all written by recognized experts in Stem Cell research reflect the tremendous progress in the understanding of stem cell biology and the appreciation of the potential for using stem cells for therapy of cancer, aging, injury and congenital diseases. Arguably the biggest advances have been made in obtaining different populations of stem cells, inducing mature cells to act like stem cells, and the ever-critical issue of how to get these stem cells to expand and differentiate into the tissue precursor cells that then can be used to replace lost of damaged tissues. No less exciting are the recent advances in understanding how stem cells function to maintain tissue integrity and how to use this knowledge to prevent developmental abnormalities. Other key topics discussed include: properties of tissue stem cells, transplantation of stem cells, the stem cell as a target for cancer treatment and prevention.
  • Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed, and the wide range of aesthetic procedures involving stem cell fat transfer are then described in detail. These procedures relate to the face, breast, buttocks, legs, hands, penis, and Poland syndrome. In addition, potential risks and complications are identified. Stem Cells in Aesthetic Procedures: Art, Science, and Clinical Techniques is completely up to date and has been written by leading experts in the field. It will be an invaluable source of information for students, beginners, and experienced surgeons in the fields of plastic surgery, general surgery, cosmetic surgery, facial plastic surgery, otolaryngology, ophthalmology, and oral maxillofacial surgery.
  • Generation of islet-like structures from ES cells / Nadya Lumelsky -- The therapeutic potential of liver repopulation for metabolic or endocrine disorders / Sanjeev Gupta -- The manipulation of mesenchymal stem cells for bone repair / Shelley R. Winn -- Spermatogenesis from transplanted spermatogenic stem cells / Michael D. Griswold and Derek McLean -- Hematopoietic stem cell transplant in the treatment of autoimmune endocrine disease / Jody Schumacher and Ewa Carrier -- Preclinical trials for stem cell therapy / Linda B. Lester, K.Y. Francis Pau, and Don P. Wolf. Pt. I. Basic stem cell biology. Embryonic stem cells: derivation, properties, and therapeutic implications / Victor L. Browning and Jon S. Odorico -- Germ line stem cells / Makoto C. Nagano -- Umbilical cord stem cells / Kathy E. Mitchell -- Differentiation potential of adult stem cells / Henry E. Young and Asa C. Black, Jr. -- Growth conditions for primate vs murine embryonic stem cells / Gillian M. Beattie ... [et al.] -- Pt. II. Translational research. Islet precursor cells in adult pancreatic islets / Gladys Teitelman and Irem Nasir -- Transcription factor-directed differentiation of stem cells along an endocrine lineage / William L. Lowe, Jr. --
  • Derivation and manipulation of murine embryonic stem cells / Alexander Meissner, Sarah Eminli, and Rudolf Jaenisch -- Patterning mouse and human embryonic stem cells using micro-contact printing / Raheem Peerani ... [et al.] -- Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi / Asmin Tulpule and George Q. Daley -- Measurement of cell-penetrating peptide-mediated transduction of adult hematopoietic stem cells / Aziza P. Manceur and Julie Audet -- Stem cell sources for regenerative medicine / Ali M. Riazi, Sarah Y. Kwon, and William L. Stanford -- Investigating the interactions between haemopoietic stem cells and their niche : methods for the analysis of stem cell homing and distribution within the marrow following transplantation / Brenda Williams and Susan K. Nilsson -- Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells / Valérie Cortin, Nicolas Pineault, and Alain Garnier -- Ex vivo generation of human red blood cells : a new advance in stem cell engineering / Luc Douay and Marie-Catherine Giarratana -- Isolation and manipulation of mammalian neural stem cells in vitro / Claudio Giachino, Onur Basak, and Verdon Taylor -- Isolation, expansion, and differentiation of mouse skin-derived precursors / Karl J.L. Fernandes and Freda D. Miller -- Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord / Hynek Wichterle, Mirza Peljto, and Stephane Nedelec -- Transplantation of neural stem/progenitor cells into developing and adult CNS / Tong Zheng ... [et al.] -- Transplantation of embrynic stem cell-derived dopaminergic neurons in MPTP-treated monkeys / Jun Takahashi, Yasushi Takagi, and Hidemoto Saiki -- Isolation and culture of epithelial stem cells / Jonathan A. Nowak and Elaine Fuchs -- Regeneration of skin and cornea by tissue engineering / Danielle Larouche ... [et al.] -- Prospective isolation of mesenchymal stem cells from mouse compact bone / Brenton J. Short, Nathalie Brouard, and Paul J. Simmons -- Isolation, propagation, and characterization of human umbilical cord perivascular cells (HUCPVCs) / Rahul Sarugaser ... [et al.] -- Bone marrow-derived mesenchymal stem cells : isolation, expansion, characterization, viral transduction, and production of conditioned medium / Massimilano Gnecchi and Luis G. Melo -- Template DNA-strand co-segregation and asymmetric cell division in skeletal muscle stem cells / Vasily Shinin, Barbara Gayraud-Morel, and Shahragim Tajbakhsh -- Isolation and grafting of single muscle fibres / Charlotte A. Collins and Peter S. Zammit -- Differentiation and dynamic analysis of primitive vessels from embryonic stem cells / Gefei Zeng and Victoria L. Bautch -- Derivation of contractile smooth muscle cells from embryonic stem cells / Sanjay Sinha, Mark H. Hoofnagle, and Gary K. Owens -- Islet-derived progenitors as a source of in vitro islet regeneration / Stephen Hanley and Lawrence Rosenberg -- Isolation and characterization of hepatic stem cells, or "oval cells," from rat livers / Thomas D. Shupe ... [et al.] -- Reprogramming of liver to pancreas / Shifaan Thowfeequ ... [et al.]
  • "In this state-of-the-art exploration of a hugely dynamic and fast-evolving field of research, leading researchers share their collective wisdom on the role that stem cells could play in the context of physiological stress and lung injury. The text focuses on reviewing the most relevant -- and recent -- ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages. Our entire blood supply passes through the lung's alveolar units during oxygenation. This interaction with the outside world, along with the intricacies of its structure, makes the lung a highly susceptible organ that is vulnerable to numerous types of injury and infection. This means that the mechanisms of lung repair are in themselves correspondingly complex. Because of their multipotentiality, as well as the fact of the lung's relatively rapid cell turnover, stem cells are thought to be an important alternative cell-base therapy in lung injury. Despite the controversial nature of stem cell research, there has been growing interest in both local and endogenous stem cells in the lung. This highly topical book with chapters on everything from using mesenchymal stem cells in lung repair to the effect of physical activity on the mobilization of stem and progenitor cells, represents an exciting body of work by outstanding investigators and will be required reading for those with an interest in the subject."--Publisher's website.
  • Biology of the cell -- Embryonic development -- What are stem cells? -- Of mice and men: the history of the stem cell -- Origins and types of stem cells -- Cloning -- Regenerative medicine: clinical applications of stem cells -- Cardiomyocytes from stem cells: what can we do with them? -- Stem cell tourism --Stem cells in cancer and cancer stem cells -- Stem cells for discovery of effective and safe new drugs -- Legal and intellectual property issues associated with stem cells -- Stem cell perspectives: a vision of the future.
  • Myogenic potential of stem cells: in vivo assessment / Maximilien Bencze [and five others] -- Urine-derived stem cells: biological characterization and potential clinical applications / Guihua Liu, Chunhua Deng and Yuanyuan Zhang -- Immunoregulatory properties of mesenchymal stem cells: in vitro and in vivo / Pinar Çetinalp Demircan [and three others] -- Current research on stem cells in Parkinson's Disease: progress and challenges / Ria Thomas and Jan Pruszak -- Stem cell applications in retinal diseases / Güngör Sobacı -- Potential use of dental stem cells for craniofacial tissue regeneration / Mustafa Ramazanoglu [and three others] -- Pediatric diseases and stem cells: recent advances and challenges / Duygu Uçkan -- Stem cell therapy: from the heart to the periphery / Bernd Stratmann and Diethelm Tschoepe -- Stem cells in wound healing / Dilek Telci, Ayca Zeynep Ilter and Merve Erdem -- Cancer stem cells: the gist of the matter / Torben Redmer [and five others] -- Filling the gap in the relationship between cancer and stem cells / Erdal Karaoz [and two others] -- Neural stem cells as therapeutic delivery vehicles for malignant brain tumors / Tugba Bagci-Onder -- Therapy resistance in prostate cancer: a stem cell perspective / Sandra Klein [and three others] -- Mechanisms of somatic cell reprogramming / Tamer T. Onder -- Disease modeling and drug discovery using human pluripotent stem cells / Christian Honoré and Mattias Hansson -- Stem cell research: ethical considerations / Berna Arda [and two others].
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    Basic concepts -- The nervous system -- The cardiovascular system -- The respiratory system -- The gastrointestinal system -- The renal system -- The endocrine system -- The reproductive system -- The musculoskeletal system -- The hematopoietic and lymphoreticular system.
  • . Case for Evidence-Based Stepped Care as Part of a Reformed Delivery System / Crissa Draper -- 2. Depression and a Stepped Care Model / Scott T. Gaynor -- 3. Anxiety / Holly Hazlett-Stevens -- 4. Panic Disorder / Per Carlbring -- 5. Post-traumatic Stress Disorder / Matthew Ghiglieri -- 6. Social Phobia (Social Anxiety Disorder) / Per Carlbring -- 7. Substance Abuse / Jason Lillis -- 8. Evaluating a Web-Based Cognitive Behavioral Intervention for the Prevention and Treatment of Pediatric Obesity / William T. O'Donohue -- 9. Chronic Disease Management / Victoria Mercer -- 10. Oppositional Defiant Disorder / Bruce M. Gale -- 11. Autism / Michele P. Steever -- 12. Grief / Brett Litz -- 13. Sexual Disorders / M. Todd Sewell -- 14. Stepped Care and E-Health in Behavioral Managed Care / Ronald R. O'Donnell -- 15. Cultural Considerations in Stepped-Care and E-Health Interventions / Chelsea Klinkebiel.
  • Definition, prevalence, and burden of oropharyngeal dysphagia : a serious problem among older adults worldwide and the impact on prognosis and hospital resources / Cichero, J.A.Y. ; Altman, K.W. -- The physiology of deglutition and the pathophysiology and complications of oropharyngeal dysphagia / Steele, C.M. -- Identifying vulnerable patients : role of the EAT-10 and the multidisciplinary team for early intervention and comprehensive dysphagia care / Kaspar, K. ; Ekberg, O. -- The volume-viscosity swallow test for clinical screening of dysphagia and aspiration / Rofes, L.; Arreola, V.; Clavé, P. -- Videofluoroscopic swallow study : techniques, signs, and reports / Bülow, M. -- Screening and clinical assessment of oropharyngeal dysphagia / Martino, R -- Pathophysiology, relevance, and natural history of oropharyngeal dysphagia among older people / Clavé, P. ... [et al.] -- Complications of oropharyngeal dysphagia : aspiration pneumonia / Almirall, J.; Cabré, M.; Clavé, P. -- Nutrition assessment and intervention in the patient with dysphagia : challenges for quality improvement / Ochoa, J.B. -- Therapeutic approach to malnutrition and sarcopenia / Burgos Peláez, R. -- Importance of nutritional support in older people / Sánchez-García, E. ... [et al.] -- Exercise-based approaches to dysphagia rehabilitation / Steele, C.M. -- Oropharyngeal dysphagia pathophysiology, complications, and science-based interventions / Altman, K.W. -- Concluding remarks.
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    Normal anatomy -- Congenital malformations -- Degenerative lesions --Inflammatory lesions -- Tumors -- Traumatic lesions -- Surgery-related lesions.
  • Since its introduction about sixty years ago, stereotactic and functional neurosurgery has evolved into a fascinating and interdisciplinary endeavor that combines modern neurosurgery, neurobiology, and neuroimaging with innovative diagnostic and treatment strategies. In this collection, acknowledged experts from Europe and North and South America present their scientific and clinical experience in stereotactic and functional neurosurgery for movement disorders and brain tumors. The contributions present a wide range from the beginnings of human stereotactic neurosurgery to the most modern molecular and restorative strategies to treat diseases of the human nervous system. They clearly demonstrate that the discipline is still young and dynamic with alternative and sometimes competing strategies whose evaluation is underway. They also document that operative lesioning techniques such as thalamotomies, though still chosen under certain circumstances, have been succeeded by novel neuromodulation techniques such as deep brain stimulation in the great majority of clinical cases.
  • Introduction / Simon S. Lo, Bin S. Teh, Jiade J. Lu and Tracey E. Schefter -- Historical Development of Stereotactic Ablative Radiotherapy / Timothy D. Solberg, Robert L. Siddon and Brian Kavanagh -- CyberKnife System / Jun Yang, John P. Lamond, Jing Feng, Xiaodong Wu and Rachelle Lanciano, et al. -- Novalis and Varian Systems / Isaac I. Rosen and Ramiro Pino -- Helical TomoTherapy System / Whitney Warren, Walter H. Grant III and Bin S. Teh -- Elekta System / Julian R. Perks, Megan E. Daly, David Schlesinger and Stanley H. Benedict -- Treatment Planning for Stereotactic Body Radiation Therapy / Moyed Miften, Shiva K. Das, Indrin J. Chetty and David Westerly -- Launching a Stereotactic Body Radiation Therapy Program / Michael Lamba -- Radiobiology of Stereotactic Body Radiation Therapy/Stereotactic Ablative Radiotherapy / Michael D. Story, Chaitanya Nirodi and Clinton Park -- Primary Lung Cancer / Joe Y. Chang, Shervin M. Shirvani, Billy W. Loo Jr., John P. Lamond and Ben J. Slotman, et al. -- Primary Liver Cancer / Higinia R. Cárdenes and Foster Lasley -- Prostate Cancer / Hiromichi Ishiyama, Alan Katz, Angel I. Blanco, Jose Hinojosa and Simon S. Lo, et al. -- Renal Cell Carcinoma / Bin S. Teh, Hiromichi Ishiyama, Angel I. Blanco, Lee E. Ponsky and Simon S. Lo, et al. -- Gynecologic Cancer / Charles A. Kunos, Jeffrey Fabien, Yuxia Zhang, James Brindle and Nina A. Mayr -- Pancreatic Cancer / A. Yuriko Minn, Daniel T. Chang and Albert C. Koong -- Benign and Malignant Primary Spinal Tumors / Brett Cox, Iris C. Gibbs and Yoshiya Yamada -- Non-Skull Base Head and Neck Cancer / Farzan Siddiqui, David Raben, Sue S. Yom, Jiade J. Lu and Min Yao -- Skull Base Head and Neck Cancer / Sue S. Yom, David Raben, Farzan Siddiqui, Jiade J. Lu and Min Yao -- Lung Metastasis / Neha Amin, Tracey E. Schefter, Paul Okunieff, Brian Kavanagh and Michael T. Milano -- Liver Metastasis / Michelle Stinauer, Rachelle Lanciano, Tracey E. Schefter, Brian Kavanagh and Julie A. Carlson, et al. -- Adrenal Metastasis / Mirna Abboud, Simon S. Lo, Arnold C. Paulino, Daniel E. Lehane and Bin S. Teh -- Histology-Specific Metastasis / Michael T. Milano and Joseph K. Salama -- Bone Metastasis / Mirna Abboud, Arnold C. Paulino, B. S. Teh, Simon S. Lo and Rex Marco -- Spinal Metastasis / Simon S. Lo, Andrew E. Sloan, Mitchell Machtay, Bin S. Teh and Arjun Sahgal, et al. -- Reported Toxicities Associated with Stereotactic Body Radiation Therapy / Simon S. Lo, Arjun Sahgal, Charles A. Kunos, Bin S. Teh and Min Yao, et al. -- Normal Tissue Constraints / Simon S. Lo, Arjun Sahgal, Lijun Ma, Ben J. Slotman and Zhibin Huang, et al. -- Erratum: Primary Liver Cancer / Higinia R. Cárdenes and Foster Lasley -- Erratum: Bone Metastasis / Mirna Abboud, Arnold C. Paulino, B. S. Teh, Simon S. Lo and Rex Marco.
  • Stereotactic body radiation therapy : lung cancer / Simon S. Lo, Bin S. Teh, Nina A. Mayr & Mitchell Machtay -- Stereotactic body radiation therapy and lung cancer / Gregory M.M. Videtic -- Radiobiology of stereotactic body radiation therapy / Zhibin Huang, Nina A. Mayr, Simon S. Lo & William Yuh -- SBRT : frame-based and image-guided strategies / Meredith Elana Giuliani & Andrea Bezjak -- CyberKnife®-based SBRT for lung cancer / Martina Descovich, Danita Kannarunimit & Sue S. Yom -- SBRT : evolving standards in tumor response evaluation / W. Alexander Wilson & Ronald C. McGarry -- Radiation pneumonitis prediction and management / Robert Bryan Barriger -- Chest wall toxicities : prediction and management / Robert Bryan Barriger -- Surgery versus SBRT for early-stage lung cancer : a new treatment option? / W. Alexander Wilson & Ronald C. McGarry -- Target contouring & treatment planning in lung SBRT / Meredith Elana Giuliani & Jean-Pierre Bissonnette -- Ask the experts : strategies to minimize complications from SBRT for lung cancer / Simon S. Lo, Bin S. Teh, Nina A. Mayr & Mitchell Machtay -- Multiple choice questions : answers.
  • This practical guide covers the basic aspects of stereotactic radiotherapy systems and treatment. As an emerging field, stereotactic body radiotherapy (SBRT) offers image-guided radiation that is directed at extremely well-defined tumor targets within the body, delivering very high doses of radiation. Indications for SBRT have expanded extensively in recent years from intracranial treatment to extracranial, leading to the development of a thriving subspecialty within radiation oncology. The expertise on these methods is concentrated across a few centres, mainly in the USA. However, as the technique is increasingly being adopted worldwide, specialists require further training in using it. Stereotactic Body Radiotherapy ? A Practical Guide provides a valuable aid for this purpose and is of particular interest to clinical oncologists and their trainees.
  • This comprehensive book encompasses various facets of sterile product development. Key concepts relevant to the successful development of sterile products are illustrated through case studies and are covered under three sections in this book: Formulation approaches that discuss a variety of dosage forms including protein therapeutics, lipid-based controlled delivery systems, PEGylated biotherapeutics, nasal dosage form, and vaccines, Process, container closure and delivery considerations including freeze-thaw process challenges, best practices for technology transfer to enable commercial product development, innovations and advancement in aseptic fill-finish operations, approaches to manufacturing lyophilized parenteral products, pen / auto-injector delivery devices, and associated container closure integrity testing hurdles for sterile product closures, Regulatory and quality aspects in the areas of particulate matter and appearance evaluation, sterile filtration, admixture compatibility considerations, sterilization process considerations, microbial contamination investigations and validation of rapid microbiological methods, and dry and moist heat sterilizers This book is a useful resource to scientists and researchers in both industry and academia, and it gives process and product development engineers insight into current industry practices and evolving regulatory expectations for sterile product development.
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    This book is the first comprehensive analysis of eugenics in North America focused on the second half of the twentieth century. Based on new research the authors show why eugenic sterilization policies persisted after the 1940s in the United States and Canada. Through extensive archival research,they show how both superintendents at homes for the 'feebleminded' and pro-sterilization advocates repositioned themselves after 1945 to avoid the taint of Nazi eugenics. Drawing on interviews with victims of sterilization and primary documents, this book traces the post-1940s development of eugenic policy and shows that both eugenic arguments and committed eugenicists informed population, welfare, and birth control policy in postwar America. In providing revisionist histories of the choice movement, the anti-population growth movement, and the Great Society programs, this book contributes to public policy and political and intellectual history.
  • "Sternberg's Diagnostic Surgical Pathology is the flagship book on LWW's pathology list. This classic 2-volume reference presents advanced diagnostic techniques and the latest information on all currently known diseases. The book emphasizes the practical differential diagnosis of the surgical specimen while keeping to a minimum discussion of the natural history of the disease, treatment and autopsy findings. Contributors are asked to provide their expert advice on the diagnostic evaluation of every type of specimen from every anatomic site. This approach distinguishes it from its key competition and provides a style of a personal consultation"-- Provided by publisher.
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  • Histology -- The cell -- Epithelial cells -- Support cells and the extracellular matrix -- Contractile cells -- Nervous tissue -- Blood cells -- Immune system -- Blood and lymphatic circulatory systems and heart -- Respiratory system -- Alimentary tract -- Liver -- Musculoskeletal system -- Endocrine system -- Urinary system -- Male reproductive system -- Female reproductive system -- Skin and breast -- Special senses.
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  • This Forum on Health and National Security, directed to addressing stigma and barriers to care, brought together a diverse group of leaders in order to expand horizons on these issues of important national need in times of war, disaster and terrorism. The individuals represented national leaders, educators, researchers and health care planners across mental health, health care systems, military and disaster care and the specific issues of stigma and barriers to care. The goal was for individuals who did not usually talk with each other or even know of each other's work, to hear new perspectives and create a new vantage point on this difficult topic.
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    Part 1. Tom the Scot -- 1. The Demographic setting; Scotland -- 2. The Scottish phase -- 3. Schooling and University Medical School -- 4. Tom the scientist clinician; how the apprentice became a pioneer of haemophilia research -- Interlude - Journey to San Francisco -- Part 2. Tom the American -- 5. California and San Francisco -- 6. American family connections -- 7. Tom the scientist clinician in America -- 8. Tom the social and political activist -- 9. Last years -- Notes and references from archived sources.
  • Technology for peripheral nerve stimulation / Parker, J.L., Cameron, T. -- Theoretical basis of vagal nerve stimulation / Attenello, F., Amar, A.P., Liu, C., Apuzzo, M.L.J. -- Vagal nerve stimulation : surgical technique and complications / Tronnier, V.M. -- Vagus nerve stimulation for epilepsy : an evidence-based approach / Cukiert, A. -- Vagus nerve stimulation for major depressive episodes / Eljamel, S. -- Phrenic nerve stimulation : technology and clinical applications / Abdunnur, S.V., Kim, D.H. -- Trigeminal ganglion stimulation / Van Buyten, J.-P. -- Carotid sinus/nerve stimulation for treatment of resistant hypertension and heart failure / Yin, D., Slavin, K.V. -- Hypoglossal nerve stimulation for obstructive sleep apnea / Mwenge, G.B., Rombaux, P., Lengele, B., Rodenstein, D. -- Sphenopalatine ganglion stimulation in neurovascular headaches / Schoenen, J. -- Occipital stimulation for migraine : update from recent multicenter trials -- Schwedt, T.J., Green, A.L., Dodick, D.W. -- Peripheral nerve stimulation for back pain / Verrills, P., Russo, M. -- Peripheral nerve stimulation for pain in extremities : an update / Pope, J.E., Carlson, J.D., Rosenberg, W.S., Slavin, K.V., Deer, T.R. -- Peripheral neuromodulation to treat postamputation pain / Soin, A., Fang, Z.-P., Velasco, J. -- Peripheral neurostimulation with a microsize wireless stimulator / Yearwood, T.L., Perryman, L.T. -- Sacral neuromodulation for genitourinary problems / Banakhar, M., Hassouna, M. -- Sacral nerve stimulation in the treatment of bowel disorders / Nordenstam, J., Boller, A.-M., Mellgren, A. -- Stimulation of the dorsal root / Ganglion Liem, L. -- Regulation of peripheral nerve stimulation technology / Birk, D.M., Yin, D., Slavin, K.V.
  • Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authors concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation.
  • "Revised and updated for its Third Edition, Stocker and Dehner's Pediatric Pathology provides encyclopedic coverage of the diagnosis of pediatric disorders from the neonatal period through adolescence. It covers all major aspects of the pathologic anatomy of childhood disorders ranging from chromosomal syndromes and neoplasms to forensic pathology. Sections are organized by disease classification and by organ system. The book contains more than 1,300 gross and microscopic images, including 1,200 in full color. This edition includes a new chapter on transplantation pathology. Other highlights include significant updates in the areas of pediatric autopsy, imaging techniques, molecular techniques, embryonic and fetal wastage, congenital abnormalities, metabolic disorders, SIDS and forensic pathology, the placenta, and the nervous system"--Provided by publisher.
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    1 General considerations and an outline survey of some basic interaction mechanisms -- 2 ACE inhibitors and angiotensin II receptor antagonists -- 3 Alcohol -- 4 Alpha blockers -- 5 Anaesthetics and neuromuscular blockers -- 6 Analgesics and NSAIDs -- 7 Anorectics and stimulants -- 8 Anthelmintics, antifungals and antiprotozoals -- 9 Antiarrythmics -- 10 Antibacterials -- 11 Anticholinesterases -- 12 Anticoagulants -- 13 Antidiabetics -- 14 Antiepileptics -- 15 Antihistamines -- 16 Antimigraine drugs -- 17 Antineoplastics -- 18 Antiparkinsonian and related drugs -- 19 Antiplatelet drugs and thrombolytics -- 20 Antipsychotics, anxiolytics and hypnotics -- 21 Antivirals -- 22 Beta blockers -- 23 Calcium-channel blockers -- 24 Cardiovascular drugs, miscellaneous -- 25 Digitalis glycosides -- 26 Diuretics -- 27 Gastrointestinal drugs -- 28 Hormonal contraceptives and sex hormones -- 29 Immunosuppressants -- 30 Lipid regulating drugs -- 31 Lithium -- 32 MAOIs -- 33 Respiratory drugs -- 34 -- SSRIs, tricyclics and related antidepressants -- 35 Miscellaneous drugs.
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    Ischemic heart disease / Shamsuddin Akhtar -- Valvular heart disease / Adriana Herrera -- Congenital heart disease / Inna Maranets and Roberta L. Hines -- Abnormalities of cardiac conduction and cardiac rhythm / Kelly Teed Watson -- Systemic and pulmonary arterial hypertension / Matthew C. Wallace and Ala Sami Haddadin -- Heart failure and cardiomyopathies / Wanda M. Popescu -- Pericardial diseases and cardiac trauma / Raj K. Modak -- Vascular disease / Marbelia Gonzalez -- Respiratory diseases / Viji Kurup -- Diseases affecting the brain / Jeffrey J. Pasternak and William L. Lanier, Jr. -- Spinal cord disorder / Jeffrey J. Pasternak and William L. Lanier, Jr. -- Diseases of the autonomic and peripheral nervous systems / Jeffrey J. Pasternak and William L. Lanier, Jr. -- Diseases of the liver and biliary tract / Katherine E. Marschall -- Diseases of the gastrointestinal system/ Hossan Tantawy -- Nutritional diseases and inborn errors of metabolism / Hossan Tantawy -- Renal diseases / Susan Garwood -- Fluid, electrolytes, and acid-base disorders / Susan Garwood -- Endocrine disease / Russell T. Wall III -- Hematologic disorders / Christine S. Rinder -- Skin and musculoskeletal diseases / Jeffrey J. Schwartz -- Infectious diseases / Michael S. Avidan -- Cancer / Nalini Vadivelu -- Diseases related to immune system dysfunction / Christine S. Rinder -- Psychiatric disease/substance abuse/drug overdose / Roberta L. Hines, Katherine E. Marschall -- Pregnancy-associated diseases / Ferne R. Braveman -- Pediatric diseases / Charles Lee ... [et al.] -- Geriatric disorders / Zoltan G. Hevesi.
  • With this book you'll have the succinct, yet guidance you need to successfully avoid or manage complications stemming from pre-existing medical conditions. Advanced research from experts in the field will help you overcome the toughest challenges in practice, letting you offer your patients the best care, each and every time. Search through current and concise descriptions of pathophysiology of diseases and their impact on anesthesia! Gain expertise in understanding the impact of pathophysiology of coexisting diseases on anaesthesia!
  • Store-operated Ca2+ entry (SOCE) serves to control essential functions throughout the human body and represents a novel and attractive target for therapeutic intervention. This book provides an extensive overview of the role of SOCE pathways in Molecular Physiology and Cell Biology, as well as their clinical significance. (Patho)physiological principles and emerging therapeutic strategies are delineated in a way that is valuable both for the education of graduate students in advanced Cell Biology/Molecular Physiology and for the promotion of innovative research and developments in the clinical/therapeutic fields. A comprehensive, clear and elaborate representation of current concepts is provided, including a pathophysiological section arranged in a tissue/organ/system-oriented manner. The book is intended for basic researchers specializing in cell signaling, ion transport, or pharmacology, as well as biomedical scientists and clinicians with a focus on immunology, neurology or cardiology.
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    Foreward: The Lasting Legacy of Sidney R. Garfield, M.D. / by Jay Crosson -- Preface -- Prologue: The Desert Doctor -- 1. Out of the Immigrant Forge -- 2. The Great Depression and "Social Medicine" -- 3. Revolution in the Economics of Medicine -- 4. A Fateful House Call -- 5. The Final Dress Rehearsal -- 6. FDR to Garfield: "You're Not in the Army Now!" -- 7. Postwar Challenges: Rebuilding Against a Tide of Opposition -- 8. Attack from the Rear Guard -- 9. Prosperity in the Postwar Boom -- 10. Toward Tahoe: Crises and Crossroads -- 11. After Tahoe: Pursuing New Frontiers -- 12. The Best is Yet to Come -- Appendix 1. Remarks to the AMA on Promoting Prepaid Group Practice -- Appendix 2. A Report on Permanente's First 10 Years -- Appendix 3. From An Address to the Permanente Monterey Management Conference -- Appendix 4. From An Address to the Board of Directors of The Permanente Medical Group -- Appendix 5. The Delivery of Medical Care / by Sidney R. Garfield -- Bibliography -- Selected Works: Authored or Coauthored by Sidney R. Garfield, M.D. (p. 135-137) -- Index -- A Timeline of the Life of Sidney R. Garfield, M.D.
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    A Harvard evolutionary biologist presents an engaging discussion of how the human body has evolved over millions of years, examining how an increasing disparity between the needs of Stone Age bodies and the realities of the modern world are fueling a paradox of greater longevity and chronic disease.
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  • Technology is essential to the delivery of health care but it is still only a tool that needs to be deployed wisely to ensure beneficial outcomes at reasonable costs. Among various categories of health technology, medical equipment has the unique distinction of requiring both high initial investments and costly maintenance during its entire useful life. This characteristic does not, however, imply that medical equipment is more costly than other categories, provided that it is managed properly. The foundation of a sound technology management process is the planning and acquisition of equipment, collectively called technology incorporation. This lecture presents a rational, strategic process for technology incorporation based on experience, some successful and many unsuccessful, accumulated in industrialized and developing countries over the last three decades. The planning step is focused on establishing a Technology Incorporation Plan (TIP) using data collected from an audit of existing technology, evaluating needs, impacts, costs, and benefits, and consolidating the information collected for decision making. The acquisition step implements TIP by selecting equipment based on technical, regulatory, financial, and supplier considerations, and procuring it using one of the multiple forms of purchasing or agreements with suppliers. This incorporation process is generic enough to be used, with suitable adaptations, for a wide variety of health organizations with different sizes and acuity levels, ranging from health clinics to community hospitals to major teaching hospitals and even to entire health systems. Such a broadly applicable process is possible because it is based on a conceptual framework composed of in-depth analysis of the basic principles that govern each stage of technology lifecycle. Using this incorporation process, successful TIPs have been created and implemented, thereby contributing to the improvement of healthcare services and limiting the associated expenses.
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  • A structured strategic management approach is what's needed to tackle the revolutionary change the health care system has been experiencing. Today, health care organizations have almost universally embraced the strategic perspective first developed in the business sector and now have developed strategic management processes that are uniquely their own. Health care leaders have found that strategic thinking, planning, and managing strategic momentum are essential for coping with the dynamics of the health care industry. Strategic Management has become the single clearest manifestation of eff
  • Strategic Urban Health Communication Charles C. Okigbo, editor People are bombarded with messages continuously and sorting through them constantly. In this milieu, critical ideas about health promotion and illness prevention are forced to compete with distracting, conflicting, even contradictory information. To get vital messages through, communication must be effective, targeted, artful-in a word, strategic. Strategic Urban Health Communication provides a road map for understanding strategy, enhancing strategic planning skills, and implementing strategic communication campaigns. Deftly written chapters link the art and science of strategic planning to world health goals such as reducing health inequities and eradicating diseases. Flexibility is at the heart of these cases, which span developed and developing countries, uses of traditional and digital media, and chronic and acute health challenges. And the contributors ground their dispatches in the larger context of health promotion, giving readers useful examples of thinking globally while working locally. Included in the coverage: Urbanization, population, and health myths: addressing common misconceptions. Integrating HIV/family planning programs: opportunities for strategic communication. The role of sports in strategic health promotion in low-income areas. The Internet as a sex education tool: a case study from Thailand. Advertising and childhood obesity in China. Health communication strategies for sustainable development in a globalized world. Balancing depth of understanding of audiences and methods of reaching them, Strategic Urban Health Communication is a forward-looking resource geared toward professionals and researchers in urban health, global health, and health communication.
  • Stratified medicine : a new challenge for academia, industry, regulators and patients -- Stratified medicine : a new era in the therapeutic approach -- Challenges for academic medicine and clinicians -- Challenges for diagnostics industry -- Challenges for the pharmaceutical industry -- Separate or codevelopment of biomarker and drug : the scenarios -- Challenges for the regulatory agencies in establishing an environment favorable for stratified medicine -- Challenges for the patients facing stratified medicine & personal genomics -- Conclusions & outlook to the future health system -- Stratified medicine : a challenging social experiment.
  • "Injury accounts for a significant proportion of the world's burden of disease. Each year 5.8 million people die from injury and millions more are disabled. The response to this global health problem needs to include a range of activities, from better surveillance to more in-depth research, and primary prevention. Also needed are efforts to strengthen care of the injured. The World Health Organization (WHO) has responded to this need with a variety of actions. ... WHO collected this set of case studies, documenting success stories and lessons learned from several countries. Through this publication, WHO seeks to increase communication ... among those working in the field of trauma care in different countries worldwide."--p. iii.
  • Introduction to Cardiovascular Disease, Stress and Adaptation -- Social Stress and Cardiovascular Disease in Primates -- Cardiovascular and Autonomic Responses to Stress -- Sympathetic Neural and Adrenal Medullary Mechanisms in Depression and Panic Disorder -- Hypothalamic-Pituitary-Adrenal Axis and Cardiovascular Disease -- Haemostatic Effects of Stress -- Stress, Inflammation, and Coronary Heart Disease -- Brain Imaging of Stress and Cardiovascular Responses -- Psychological Triggers for Plaque Rupture -- Stress Cardiomyopathy -- Psychosocial Factors at Work: The Epidemiological Perspective -- Depression and Cardiovascular Disease Progression: Epidemiology, Mechanisms and Treatment -- Post-traumatic Stress Disorder: Emerging Risk Factor and Mechanisms -- Sleep, Stress, and Heart Disease -- The Causal Role of Chronic Mental Stress in the Pathogenesis of Essential Hypertension -- Metabolic Syndrome and Diabetes -- Stress Management and Behavior: From Cardiac Patient to Worksite Intervention -- Exercise to Reduce Distress and Improve Cardiac Function: Moving on and Finding the Pace -- The Psychological Treatment of Cardiac Patients -- Integrating the Management of Psychosocial and Behavior Risk Factors into Clinical Medical Practice -- Concluding Remarks.
  • Are oral disorders only an issue for dentists? The answer is no. If your patients complain of pain and/or discomfort, if some are diagnosed as suffering from migraines, fibromyalgia or chronic fatigue, and if classical therapies have remained ineffective, this book could help in your daily practice. When it comes to the complex pathology called Temporo-Mandibular Disorders (TMD) most specialists favour a multidisciplinary approach and treatment of socio-psycho-emotional factors as well as dental, lingual or postural disorders. Yet little is known - from a clinical point of view - about a tricky oral spastic habit called severe teeth clenching. In view of the lack of clinical findings from classical investigations on the subject, it could be considered as the hidden part of an oral parafunctional iceberg. Neuroscience has been able to shed some light on the multiple connections between trigeminal and non-trigeminal nervous centres, which confirms the significant involvement of the stomatognathic system and trigeminal nerves (V) in both oral as well as non-oral major functions such as eating, breathing, speaking, hearing, and standing and also confirms the extensive participation of the paired Vs in the human adaptation process. Too many physicians are still reluctant to admit the pathological responsibilities of the Vs. Therefore their role remains largely underestimated by clinicians. Stress conditions in introverted people cause a parafunctional habit (i.e. severe clenching), which in turn produces trigeminal overstimulation and nociception. Through a process of sensitization this can perturb some non-trigeminal nervous areas, such as the vestibular nuclei and cerebellum (involved in equilibrium). Would you then be willing to accept the possibility that a stressed and introverted patient who clenches hard, durably or frequently may end up suffering from dizziness? If not, this book is not for you. But if you accept the scientific data and clinical facts this book will offer a concrete therapeutic protocol: the Relaxing and Moderating Treatment (RMT), which can greatly help you to familiarize yourself with and neutralize this little known deleterious spastic oral parafunction and its many disconcerting pain-causing and dysfunctional clinical effects. Prepare to be amazed by the results, just as we were!
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    v. 1. Coping with normative transitions -- v. 2. Coping with catastrophe.
  • This book adopts an interdisciplinary approach in seeking to identify the impact of living conditions in space on the adaptation of the immune system.
  • Part I: Presentation and Diagnosis of Stress Fractures -- Pathophysiology and Epidemiology of Stress Fractures -- General Treatment Concepts for Stress Fractures -- Biomechanics and Gait Analysis for Stress Fractures -- Classification of Stress Fractures -- Imaging of Stress Fractures -- Part II: Management of Stress Fractures -- Stress Fractures of the Lumbar Spine -- Stress Fractures of the Pelvis -- Stress Fractures of the Femur -- Stress Fractures of the Patella -- Stress Fractures of the Tibia -- Stress Fractures of the Fifth Metatarsal -- Stress Fractures of the Ankle -- Stress Fractures of the Calcaneus, Sesamoids and Metatarsals -- Stress Fractures of the Ribs and Shoulder Girdle -- Upper Extremity Stress Fractures -- Insufficiency Fractures.
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    "We live in an age of stress. Constant stress significantly affects our ability to lead healthy and happy lives at work and home. We struggle with stomach pain, headaches, mood swings, fatigue, depression, high blood pressure, and even heart failure. Stress damages our physical and emotional well-being, our relationships, and our productivity. Dr. Fred Luskin and Dr. Kenneth R. Pelletier spent years at the Stanford University School of Medicine developing ten proven skills for eliminating the stress, anxiety, and pain that occur in daily life. Delivering sound advice, Stress Free for Good is easy to use and starts working immediately. This is the last stress aid you will ever need"--Book jacket.
  • Stress in America missing the health care connection. 2014
    American Psychological Association
    While the United States spends more than any other country on health care and leads the world in the quality and quantity of its health research, these trends do not add up to better health outcomes. he U.S. experiences poorer health outcomes than many other high-income countries, even while spending more money per person on health care. Compared to peers in these countries, Americans have less access to primary care, consume the most calories per person and are more likely to live in environments designed around automobiles. Research suggests that these factors contribute to the nation's poor health outcomes and survey findings show that stress influences our health behaviors, setting up teens and adults alike for potential chronic illnesses that affect quality of life and the country's health care expenditure.
  • pt. 1. Psychological challenges of heart disease -- pt. 2. Psychological interventions for cardiac patients.
  • Neurobehavioral medicine and stress-related disorders / Dirk H. Hellhammer, Juliane Hellhammer -- Neuropattern : a step towards neurobehavioral medicine / Dirk H. Hellhammer, Juliane Hellhammer -- Principles of the crosstalk between brain and body : glandotropy, ergotropy, and trophotropy / Dirk H. Hellhammer -- Hypercortisolemic disorders / Petra Pütz -- Hypocortisolemic disorders / Eva Fries -- Noradrenergic and sympathetic disorders / Pascal O. Klingmann, Dirk H. Hellhammer -- Serotonergic and parasympathetic disorders / Dirk H. Hellhammer, Pascal O. Klingmann.
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    Evaluating the role of Hans Selye in the modern history of stress / Mark Jackson -- Stress and the American vernacular : popular perceptions of disease causality / Elizabeth Siegel Watkins -- Resilience for all by the year 20? / Allan Young -- From primitive fear to civilized stress : sudden unexpected death / Otniel E. Dror -- Stress in US wartime psychiatry : World War II and the immediate aftermath / Theodore M. Brown -- The machinery and the morale : physiological and psychological approaches to military stress research in the early Cold War era / Tulley Long -- Making sense of workplace fear : the role of physicians, psychiatrists, and labor in reframing occupational strain in industrial Britain, ca. 1850-1970 / Joseph Melling -- Work, stress, and depression : the emerging psychiatric science of work in contemporary Japan / Junko Kitanaka -- The invention of the 'stressed animal' and the development of a science of animal welfare, 1947-86 / Robert G. W. Kirk -- Memorial's stress : Arthur M. Sutherland and the management of the cancer patient in the 1950s / David Cantor -- Stress in the city : mental health, urban planning, and the social sciences in the postwar United States / Edmund Ramsden -- Sadness in Camberwell : imagining stress and constructing history in postwar Britain / Rhodri Hayward.
  • 1. Stress-induced mutagenesis in bacteria / Ivan Matic -- 2. Mutagenesis associated with repair of DNA double-strand breaks under stress / Chandan Shee, P.J. Hastings, and Suman M. Rosenberg -- 3. Transcription-mediated mutagenic processes / Eduardo Robleto, Holly A. Martin, Carmen Vallin, Mario Pedraza-Reyes and Ronald Yasbin -- 4. Transposon mutagenesis in disease, drug discovery, and bacterial evolution / Zhongge Zhang, Jing Wang, Maksim A. Shlykov, and Milton H. Saier, Jr. -- 5. Hsp90 as a capacitor of both genetic and epigenetic changes in the genome during cancer progression and evolution / Xiangyi Lu, Luan Wang, Vincent E. Sollars, Mark D. Garfinkel, and Douglas M. Ruden -- 6. Inheritance of stress-induced epigenetic changes mediated by the ATF-2 family of transcription factors / Ki-Hyeon Seong, Toshio Maekawa and Shunsuke Ishii -- 7. Microsatellite repeats: canaries in the coalmine / Nimrat Chatterjee, Beatriz A. Santillan and John H. Wilson -- 8. Genetic instability induced by hypoxic stress / Susan E. Scanlon and Peter M. Glazer -- 9. Radiation-induced delayed genome instability and hypermutation in mammalian cells / Christopher P. Allen, Akira Fujimori, Ryuichi Okayasu and Jac A. Nickoloff -- 10. Radiation-induced bystander effects and stress-induced mutagenesis / Carmel Mothersill and Colin Seymour -- 11. Stress induced mutagenesis, genetic diversification, and cell survival via anastais, the reversal of late stage apoptosis / Ho Lam Tang, Ho Man Tang and Denise J. Mitchell -- 12. The transgenerational effects of parental exposure to mutagens in mammals / Yuri E. Dubrova -- 13. Revisiting mutagenesis in the age of High-throughput sequencing / Subhajyoti De and R. Matthew Ward.
  • Stroke book. 2nd ed. 2013
    Section I. Assessment of Stroke Patients -- 1. Emergency medical services (EMS): first line of defense against stroke -- 2. Initial assessment of patients with stroke-like symptoms -- 3. Clinical stroke syndromes and localization -- Section II. The Hunt for a Stroke Etiology -- 4. The Hunt for a stroke etiology: ischemic stroke -- 5. The Hunt for a stroke etiology: hemorrhagic stroke -- 6. Uncommon causes of stroke and stroke mimics -- Section III. Acute Stroke Imaging -- 7. Computed tomography in acute stroke -- 8. Magnetic resonance imaging in acute stroke -- 9. Neurosonology in acute ischemic stroke -- Section IV. Management of Stroke Patients -- 10. Ischemic stroke in the first 24 hours -- 11. Management of the acute ischemic stroke patient beyond 24 hours -- 12. Intracerebral hemorrhage -- 13. Subarachnoid hemorrhage and its medical management -- 14. Dural and cerebral venous thrombosis -- Section V. Stroke in Consultation -- 15. Perioperative stroke -- 16. Stroke on OB/Gyn wards -- 17. Stroke on pediatric wards -- Section VI. Prevention of First and Recurrent Stroke -- 18. Antithrombotic therapies -- 19. Surgical and endovascular therapies -- 20. Stroke risk factors: impact and management -- 21. Synopsis of landmark studies in ischemic stroke.
  • Chapter 1. Setting the goal for the stroke center -- chapter 2. Stroke center organization -- chapter 3. Regional stroke networks -- chapter 4. Imaging for diagnosis and selection of therapy -- chapter 5. Transient ischemic attack : TIA -- chapter 6. Acute stroke interventions -- chapter 7. Neurocritical care management of acute stroke -- chapter 8. Issues in acute management -- chapter 9. Prevention of complications -- chapter 10. Secondary prevention of stroke -- chapter 11. Stroke rehabilitation.
  • Stroke genetics 2013
    Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Â Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
  • Introduction to stroke genomics / Simon J. Read and Frank C. Barone -- Choice, methodology, and characterization of focal ischemic stroke models: the search for clinical relevance / David Virley -- Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat / Hilary V. O. Carswell ... [et al.] -- Gene therapy in neurological disease / Midori A. Yenari and Robert M. Sapolsky -- Stem cell transplantation after middle cerebral artery occlusion / Paul Stroemer and Helen Hodges -- Endogenous brain protection: models, gene expression, and mechanisms / Frank C. Barone -- Production of transgenic and mutant mouse models / Alex Harper -- 3-nitropropionic acid model of metabolic stress: assessment by magnetic resonance imaging / Toby John Roberts -- Practicalities of genetic studies in human stroke / Ahamad Hassan and Hugh S. Markus -- Evaluation of the interactions of common genetic mutations in stroke / Zoltán Szolnoki -- Technologies of disease-related gene discovery using preclinical models of stroke / Xinkang Wang -- Quantitative analysis of gene transcription in stroke models using real-time RT-PCR / David C. Harrison and Brian C. Bond -- Effective analysis of genomic data / Paul R. Nelson, Andrew B. Goulter, and Richard J. Davis -- Bioinformatic approaches to assigning protein function from novel sequence data / David Michalovich and Richard Fagan -- Pragmatic target discovery from novel gene to functionally defined drug target: the interleukin-1 story / Stuart McRae Allen.
  • Stroke in children and young adults : overview, risk factors and prognosis / Betsy B. Love, José Biller -- Applied anatomy of the brain arteries / William DeMyer -- Stroke in neonates and children : overview / Meredith R. Golomb -- Diagnostic strategies in neonates, children, and young adults with stroke / Deborah K. Sokol, Hema Patel -- Atherosclerotic cerebral infarction in young adults / José Biller, Rima M. Dafer -- Non-atherosclerotic cerebral vasculopathies / Rima M. Dafer, José Biller -- Cardiac disorders and stroke in children and young adults / José Biller, Michael J. Schneck, Betsy B. Love -- Cerebral infarction and migraine / Rima M. Dafer, José Biller. Hemostatic disorders presenting as cerebral infarction / Rima M. Dafer, José Biller -- Stroke and pregnancy / Rima M. Dafer, José Biller -- Rare genetic disorders predisposing to stroke / Betsy B. Love, James F. Meschia, José Biller -- Cerebral venous thrombosis / Rima M. Dafer, José Biller -- Neonatal intracranial hemorrhage / Eugene R. Schnitzler, Marc G. Weiss -- Spontaneous intracerebral hemorrhage / José Biller, Michael Schneck -- Subarachnoid hemorrhage in young adults / Lotfi Hacein-Bey, Thomas C. Origitano, José Biller -- Pediatric CNS vascular malformations / Thomas J. Altstadt, Mitesh V. Shah -- Vascular disorders of the spinal cord in children and young adults / Richard B. Rodgers, Michael B. Pritz.
  • Stroke management and recovery / Bruce Ovbiagele -- Stroke pathophysiology / Sarkis Morales-Vidal & José Biller -- Risk factors and primary prevention / Rita V. Krishnamurthi, Kelly M. Jones & Valery L. Feigin -- Early symptoms, signs and diagnosis of stroke / Sweta Adatia & Andrew Demchuk -- Hyperacute stroke management / Edward Jauch, Christine Holmstedt & Mark McCaslin -- In-hospital management of stroke / Michel Shamy, Karl Meisel & S. Andrew Josephson -- Medications for recurrent stroke prevention / Muhammad U. Farooq & Philip B. Gorelick -- Surgical prevention of stroke / Andrew R. Barleben, Wesley S. Moore & Thomas G. Brott -- Stroke prevention : diet and lifestyle / Jorge Pagola & Carlos A. Molina -- Multidisciplinary stroke rehabilitation and prognosis / Robert W. Teasell & Ricardo Viana -- Physical and occupational therapy / Richard D. Zorowitz -- Speech and language therapy / Marlís González-Fernández & Argye E. Hillis -- Management of postdischarge complications / Bernadette N. Borte & Enrique C. Leira -- Stroke systems of care / Alec Fraser, Charles Wolfe, Anthony Rudd & Christopher McKevitt -- Index.
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    Development of knowledge about cerebrovascular disease -- Is it a vascular event and where is the lesion? -- Which arterial territory is involved? -- What pathological type of stroke is it, cerebral ischaemeic of haemorrhage? -- What caused this transient or persisting ischaemic event? -- Unusual causes of ischaemic stroke and transient ischaemic attack -- What caused this intracerebral haemorrhage? -- What caused this subarachnoid haemorrhage? -- A practical approach to the management of stroke and transien ischaemic attack patients -- What are this person's problems? a problem-based approach to the general management of stroke -- Specific treatments for acute ischaemic stroke -- Specific treatment of intracerebral haemorrhage -- Specific treatment of aneurismal subarachonoid haemorrhage -- Specific interventions to prevent intracranial haemorrhage -- Preventing recurrent stroke and other serious vascular events -- The organization of stroke services -- Reducing the impact of stroke and improving the public health.
  • Antithrombotic management of atrial fibrillation / Ron Pisters & Harry J. Crijns -- Overview of stroke in atrial fibrillation / Hans-Christoph Diener -- Stroke risk assessment in atrial fibrillation / Stavros Apostolakis & Gregory Y.H. Lip -- Treatment recommendations and guidelines / Laurent Fauchier, Nicolas Clementy & Dominique Babuty -- Pharmacological stroke prevention: antithrombotic drugs / Christian Weimar & Ralph Weber -- Pharmacological stroke prevention : RAS inhibitors / Ole Dyg Pedersen & Christian Torp-Pedersen -- Stroke prevention : antiarrhythmic treatments / A. John Camm & Irina Savelieva -- Nonpharmacological stroke prevention strategies in atrial fibrillation patients / Alessandro Montecalvo & Ralph J. Damiano -- Antithrombotic management in the acute coronary syndrome setting / Andrea Rubboli -- Periprocedural reversal & bridging of anticoagulant treatment / Marcel Levi, Elise Eerenberg & Pieter Willem Kamphuisen -- Clinical barriers to the use of recommended stroke prevention therapy / Robby Nieuwlaat -- Novel antithrombotic agents & future directions / Renee M. Sullivan & Brian Olshansky -- Index.
  • Safety and efficacy of transplanting immortalized neural stem cells in stroke patients -- Transplantation of bone marrow stromal cells for the treatment of stroke -- Cord blood cells as a treatment for stroke -- Adipose-derived stem cells as a potential therapy for stroke -- Novel imaging modalities to monitor implanted embryonic stem cells in stroke -- Cell transplantation for intracerebral hemorrhage -- Therapeutic strategies employing endogenous neural stem cells in tissue remodeling following ischemic injury: the promise, the peril and novel future applications -- Ethics and stem cell research -- Special conditions in the design of clinical stroke trials for cell transplantation.
  • Vascular biology and athersclerosis of cerebral vessels / Sophocles Chrissobolis, Christopher G. Sobey -- Mechanisms of Thrombosis and thrombolysis / Gregory J. del Zoppo -- Cerebral blood flow and metabolism : regulation and pathophysiology in cerebrovascular disease / William J. Powers -- Histopathology of brain tissue response to stroke and injury / Roland N. Auer -- Molecular and cellular mechanisms of ischemia-induced neuronal death / Haiyue Zhang [and 6 others] -- Intracellular signaling : mediators and protective responses / John W. Thompson [and 3 others] -- The neurovascular unit and responses to ischemia / Gregory J. del Zoppo, Michael Moskowitz, Maiken Nedergaard -- Mechanisms of cerebral hemorrhage / Jaroslaw Aronowski [and 3 others] -- White matter pathophysiology / Bruce R. Ransom [and 3 others] -- Inflammation and immune response / Josef Anrather, Costantino Iadecola, John Hallenbeck -- Mechanisms of plasticity, remodeling and recovery / Zheng Gang Zhang, Michael Chopp -- Genetics and vascular biology of angiogenesis and vascular malformations / Helen Kim [and 3 others] -- Global burden of stroke / Valery L. Feigin, Rita V. Krishnamurthi -- Stroke disparities / George Howard, Virginia J. Howard -- Modifiable risk factors and determinants of stroke / Sudha Seshadri, Philip A. Wolf -- Prognosis after stroke / Tatjana Rundek, Ralph L. Sacco -- Vascular dementia and cognitive impairment / Sudha Seshadri, Alexis Economos, Clinton Wright -- Genetic basis of stroke occurrence, prevention and outcome / James F. Meschia, Daniel Woo, David Werring -- Preventing a first stroke / Larry B. Goldstein, Ralph L. Sacco -- Classification of ischemic stroke / Hakan Ay --Clinical scales to assess patients with stroke / Harold P. Adams, Jr. -- Carotid artery disease / Leo H. Bonati, Martin M. Brown -- Anterior cerebral artery disease / John C.M. Brust, Angel Chamorro -- Middle cerebral artery disease / Vijay K. Sharma, Lawrence K.S. Wong -- Posterior cerebral artery disease / Jong S. Kim -- Vertebrobasilar disease / Jong S. Kim, Louis R. Caplan -- Lcunar syndromes, lacunar infarcts, and cerebral small-vessel disease / Bo Norrving -- Intracerebral hemorrhage / Carlos S. Kase [and 3 others] -- Aneurysmal subarachnoid hemorrhage / José I. Suarez, Eric M. Bershad -- Arteriovenous malformations and other vascular anomalies / Christian Stapf -- Stroke and other vascular syndromes of the spinal cord / Joshua Z. Willey -- Cardiac diseases / David M. Greer, Shunichi Homma, Karen L. Furie -- Atherosclerotic disease of the proximal aorta / Marco R. Di Tullio, Shunichi Homma -- Stroke related to surgery and other procedures / Steven R. Messé, Michael T. Mullen -- Arterial dissections and fibromuscular dysplasia / Richard M. Zweifler, Gerald Silverboard -- Collagen vascular and infectious diseases / Jose Gutierrez, Mira Katan, Mitchell S.V. Elkind -- Reversible cerebral vasoconstriction syndromes / Aneesh B. Singhal -- Hypertensive encephalopathy / Catherine Lamy, Jean-Louis Mas -- Stroke and substance abuse / John C.M. Brust -- Moyamoya disease / Masahiro Yasaka, Takenori Yamaguchi, Jun Ogata -- CADASIL : cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy / Hugues Chabriat [and 3 others] -- Hematologic disorders and stroke / Cheryl Bushnell -- Migraine and stroke / Hans Christoph Diener, Tobias Kurth -- Cryptogenic stroke / Martin O'Donnell, Scott E. Kasner -- Cerebral venous thrombosis / José M. Ferro, Patrícia Canhão -- Ultrasonography / Michal Haršány, Georgios Tsivgoulis, Andrei V. Alexandrov -- Computed tomography-based evaluation of cerebrovascular disease / Imanuel Dzialowski [and 3 others] -- Magnetic resonance imaging of cerebrovascular diseases / Maarten G. Lansberg [and 4 others] -- Cerebral angiography / Ronald J. Sattenberg [and 4 others] -- Prehospital and emergency department care of the patient with acute stroke / Anna Gensic, Arthur Pancioli -- Intravenous thrombolysis / Wendy Brown, Patrick D. Lyden -- Antithrombotic therapy for treatment of acute ischemic stroke / Harold P. Adams Jr., Patricia H. Davis -- General stroke management and stroke units / Turgut Tatlisumak, Risto O. Roine -- Critical care of the patient with acute stroke / Marek Sykora, Silvia Schönenberger, Julian Bösel -- Pharmacologic modification of acute cerebral ischemia / Nicole R. Gonzales, James C. Grotta -- Treatment of "other" stroke etiologies / Scott E. Kasner, Brett L. Cucchiara -- Medical therapy of intracerebral and intraventricular hemorrhage / Darin B. Zahuranec, Lewis B. Morgenstern -- Rehabilitation and recovery of the patient with stroke / Bruce H. Dobkin -- Interventions to improve recovery after stroke / Steven C. Cramer -- Enhancing stroke recovery with cellular therapies / Sean I. Savitz, Kaushik Parsha -- Antiplatelet therapy for secondary prevention of stroke / Thalia S. Field [and 3 others] -- Secondary prevention of cardioembolic stroke / Karen Furie, Muhib Khan -- Conduct of stroke-related clinical trials / Adriana Pérez, Barbara C. Tilley -- Endovascular therapy of extracranial and intracranial occlusive disease / Maxim Mokin, Elad I. Levy -- Endovascular treatment of acute ischemic stroke / Reza Jahan, Jeffrey L. Saver -- Endovascular treatment of cerebral aneurysms / Ajay K. Wakhloo [and 3 others] -- Interventional therapy of brain and spinal arteriovenous malformations / Timo Krings, Sasikhan Geibprasert, Karel Ter Brugge -- Dural arteriovenous malformations / Javed Khader Eliyas, Issam A. Awad -- Surgery of anterior and posterior aneurysms / Mark J. Dannenbaum [and 4 others] -- Surgery for intracerebral hemorrhage / A. David Mendelow, Barbara A. Gregson --Intraventricular hemorrhage / J. Max Findlay -- Surgical management of cranial and spinal arteriovenous malformations / Jonathan Russin, Robert F. Spetzler -- Surgical cavernous malformations and venous anomalies / Najib E. El Tecle [and 7 others] -- Indications for carotid endarterectomy in patients with asymptomatic and symptomatic carotid stenosis / John A. Braca III [and 3 others] -- Extracranial to intracranial bypass for cerebral ischemia / David W. Newell, Marcelo D. Vilela, William J. Powers -- Decompressive craniectomy for infarction and hemorrhage / Hermann Neugebauer [and 3 others]
  • I. An introduction to the prokaryotic cell. The cellular system -- II. Cellular structures and their function. The plasma membrane -- Cell wall structure -- The cell wall matrix -- Capsules, pili, and internal structure -- III. Profiles of bacterial growth. Cell motion, sensing, and communication -- Cellular growth and reproduction -- Physiological basis for growth in extreme environments -- IV. Bioenergetics. Electron transport and coupled phosphorylation -- Transmembrane movement: mechanisms and examples -- V. Metabolic processes. Pathways of carbon flow -- Organization and cellular processing -- Metabolism of nitrogen and sulfur.
  • Modeling conformational flexibility and evolution of structure : RNA as an example / P. Schuster and P.F. Stadler -- Gene3D and understanding proteome evolution / J.G. Ranea ... [et al.] -- The evolution of the globins : we thought we understood it / A.M. Lesk -- The structurally constrained neutral model of protein evolution / U. Bastolla ... [et al.] -- Towards unifying protein evolution theory / N.V. Dokholyan and E.I. Shakhnovich -- A twenty-first century view of evolution : genome system architecture, repetitive DNA, and natural genetic engineering / J.A. Shapiro -- Genomic changes in bacteria : from free-living to endosymbiotic life / F.J. Silva ... [et al.] -- Molecular phylogenetics : mathematical framework and unsolved problems / X. Xia -- Phylogenetics and computational biology of multigene families / P. Liò, M. Brilli and R. Fani -- SeqinR 1.0-2 : a contributed package to the R project for statistical computing devoted to biological sequences retrieval and analysis / D. Charif and J.R. Lobry -- Evolutionary genomics of gene expression / I.K. Jordan and L. Mariño-Ramírez -- From biophysics to evolutionary genetics : statistical aspects of gene regulation / M. Lässig -- Drift and selection in evolving interacting systems / T. Ohta -- Adaptation in simple and complex fitness landscapes / K. Jain and J. Krug -- Genetic variability in RNA viruses : consequences in epidemiology and in the development of new strategies for the extinction of infectivity / E. Lázaro.

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A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available. Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences. Includes cited reference searching, citation maps, and an analyze tool.Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not. Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.The National Guideline Clearinghouse (NGC): A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.
Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.