Books

S

  • Digital
    [edited by] Frank W. Sellke, Pedro J. del Nido, Scott J. Swanson.
    Digital : ClinicalKeyv. 1-2, 2016
    V. 1 -- Sect. 1: Thoracic surgery -- Pt. A: Evaluation and care -- Pt. B: Endoscopy -- Pt. C: Trauma -- Pt. D: Trachea -- Pt. E: Benign lung disease -- Pt. F: Lung cancer -- Pt. G: Other lung malignancy -- Pt. H: Chest wall -- Pt. I: Pleura -- Pt. J: Diaphragm -- Pt. K: Esophagus-Benign disease -- Pt. L: Esophagus-cancer -- Pt. M: Mediastinum -- Pt. N: The future -- Sect. 2: Adult cardiac surgery -- Pt. A: Basic science -- Pt. B: Diagnostic procedures -- Pt. C: Medical- and catheter-based treatment of cardiovascular disease -- Pt. D: Perioperative and intraoperative care of the cardiac surgical patient -- V. 2 -- Pt. E: Surgical management of aortic disease -- Pt. F: Surgical management of valvular heart disease -- Pt. G: Management of cardiac arrhythmias -- Pt. H: Surgical management of coronary artery disease and its complications -- Pt. I: Surgical management of heart failure -- Sect. 3: Congenital heart surgery.
  • Digital
    [edited by] Courtney M. Townsend, Jr, R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox.
    Digital : ClinicalKey2017
  • Print
    [edited by] Courtney M. Townsend, Jr., R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox.
    Print2008
    Status: Not Checked OutLane Catalog Record
  • Digital
    Digital : WHO2012
    Print2012
  • Digital
    Melinda S. Sothern.
    Digital : CRCnetBASE2014
    "Drawing on the recommendations of leading health and fitness organizations, this timely book develops a 20-week exercise program to assist children in achieving a healthy weight. Providing specific recommendations for intensity, duration, frequency, and modality of exercise for patients with significant obesity and chronic health issues such as hypertension, asthma, and diabetes, it covers aerobic exercise, strength training, flexibility training, motivation techniques, tracking techniques, measurements for health and fitness outcomes, and future trends in exercise research for overweight youth"-- Provided by publisher.
  • Print
    edited by G. Rees, K. Pond, D. Kay, J. Bartram and J. Santo Domingo.
    Print2010
    Status: Not Checked OutLane Catalog Record
    Expert consensus / G. Rees, J. Bartram and D. Kay -- Bivalves: global production and trade trends / S. Pawiro -- Adverse health outcomes / T.K. Graczyk, K. Suresh and D. Lees -- Driving forces and risk management / G. Rees, I. Karunasagar and J. Santo Domingo -- Identification of primary sources of faecal pollution / J.W. Santo Domingo and T.A. Edge -- Components of microbiological monitoring programmes / R. Lee and L. Murray -- Real-time monitoring technologies for indicator bacteria and pathogens in shellfish and shellfish harvesting waters / A.P. Dufour and G.N. Stelma Jr. -- Sanitary profiling of shellfish harvesting areas / R. Lee ... [et al.] -- Depuration and relaying / D. Lees, A. Younger and B. Doré -- Overview of legislative principles and measures / L. Murray and R. Lee -- é Scotland / L. Murray -- Official control monitoring programmes for live bivalve molluscs - legislative and regulatory approaches: Canada / G. Sauvé -- Official control monitoring programmes for live bivalve molluscs - legislative and regulatory approaches: New Zealand / P. Busby -- Current management practices / G. Rees ... [et al.] -- Experience from recreational waters / D. Kay ... [et al.] -- Microbial modelling in coastal environments and early warning systems: use full tools to limit shellfish micorbial contamination / M. Gourmelon ... [et al.] -- Framework for change / D. Kay and G. Rees.
  • Digital
    edited by Yves Chartier, Jorge Emmanuel, Ute Pieper, Annette Prüss, Philip Rushbrook, Ruth Stringer, William Townend, Susan Wilburn and Raki Zghondi.
    Digital : WHO2014
    Print2014
  • Digital
    T.S.S. Dikshith.
    Digital : CRCnetBASE2009
  • Digital
    Pasi Ahonen [and others], authors ; David Wright [and others], editors.
    Digital : Springer2010
    "This book is a warning. It aims to warn policy-makers, industry, academia civil society organisations, the media and the public about the threats and vulnerabilities facing our privacy, identity, trust, security and inclusion in the rapidly approaching world of ambient intelligence (AmI)." "In the near future, every manufactured product - our clothes, money, appliances, the paint on our walls, the carpets on our floors, our cars, everything - will be embedded with intelligence, networks of tiny sensors and actuators, which some have termed "smart dust". The AmI world is not far off. We already have surveillance systems, biometrics, personal communicators, machine learning and more. AmI will provide personalised services - and know more about us - on a scale dwarfing anything hitherto available." "In the AmI vision, ubiquitous computing, communications and interfaces converge and adapt to the user. AmI promises greater user-friendliness in an environment capable of recognising and responding to the presence of different individuals in a seamless, unobtrusive and often invisible way. While most stakeholders paint the promise of AmI in sunny colours, there is a dark side to AmI as well." "The book identifies threats and vulnerabilities and illustrates them by means of four "dark scenarios". The authors set out a structured methodology for analysing AmI scenarios and propose safeguards to counter the foreseen threats and vulnerabilities. They make recommendations to policy-makers and other stakeholders about what they can do to maximise the benefits from ambient intelligence and minimise the negative consequences."--Jacket.
  • Digital
    Charles Vincent, René Amalberti.
    Digital : Springer2016
    Progress and challenges for patient safety -- The ideal and the real -- Approaches to safety: one size does not fit all -- Seeing safety through the patient?s eyes -- The consequences for incident analysis -- Strategies for safety -- Safety strategies in hospitals -- Safety strategies for care in the home -- Safety strategies in primary care -- New challenges for patient safety -- A compendium of safety strategies and interventions -- Managing risk in the real world.
  • Print
    Lauren Elizabeth Harkinson Woodard.
    Print2009
    Status: Not Checked OutLane Catalog Record
  • Digital
    volume editors, Vera Rogiers, Marleen Pauwels.
    Digital : Karger2008
    Print2008
    Cosmetic products and their current regulatory framework -- Challenges related to cosmetic safety assessment in the EU -- Critical analysis of the safety assessment of cosmetic ingredients performed at the European level -- Safety assessment of cosmetic ingredients present in technical information files of finished products -- The cosmetic technical information file in practice -- The use of alternative methods in the safety assessment of cosmetic ingredients.
  • Digital
    Jacob O. Levitt, Joseph F. Sobanko, editors.
    Digital : Springer2015
    In medical practice, unfamiliarity with procedures increases the likelihood of occupational exposures. Learning to perform a procedure properly early on reinforces safe habits, improves overall surgical safety, and reduces occupational exposures. Safety in Office-Based Dermatologic Surgery is relevant to any healthcare professional who participates in office-based procedures, such as injections, biopsies, excisions, and laser surgery. The authors bring over 15 years? combined experience in training residents and medical students, enabling them to identify common unsafe practices in office-based surgery. Chapters are divided into individual procedures for easy referencing by students, trainees, as well as seasoned practitioners. Figures illustrate how seemingly innocuous actions and procedures can result in dangerous exposures to healthcare workers. Hazardous scenarios are subsequently followed with one or a series of safer solutions, with the accident and solution concisely explained and clearly illustrated.
  • Digital
    Brian A. Baldo.
    Digital : Springer2016
    1: Approved Biologics Used For Therapy and their Adverse Effects -- 2: Monoclonal Antibodies: Introduction -- 3: Monoclonal Antibodies Approved for Cancer Therapy -- 4: Other Approved Therapeutic Monoclonal Antibodies -- 5: Cytokines -- 6: Fusion Proteins -- 7: Peptide Hormones -- 8: Glycoprotein Hormones -- 9: Enzymes Approved for Therapy -- 10: Blood Coagulation -- 11: Vaccines -- 12: Botulinum Neurotoxins -- 13: Biosimilars.
  • Digital
    Abha Agrawal, editor.
    Digital : Springer2016
    Chapter 1. First Do No Harm: An overview of HIT and Patient Safety -- Chapter 2. An overview of HIT-related errors -- Section I. Errors Related to Various Types of Health Information Technologies -- Chapter 3. Errors related to CPOE -- Chapter 4. Errors related to alert fatigue -- Chapter 5. Unintended consequences of bar-code assisted medication administration -- Chapter 6. Errors related to outpatient e-prescribing -- Chapter 7. Errors related to alarms and monitors -- Chapter 8. Errors related to personal mobile technology -- Section II. Health Information Technology Implementation Issues -- Chapter 9. Improving clinical documentation integrity -- Chapter 10. EHR and physician-patient communication -- Chapter 11. Patient identification errors and HIT: Friend or foe? -- Chapter 12. Errors related to health information exchange -- Section III. Specialty Considerations -- Chapter 13. Safety considerations in radiation therapy -- Chapter 14. Safety considerations in pediatric informatics -- Chapter 15.Safety considerations in ambulatory care informatics -- Section IV. Organizational Considerations -- Chapter 16. Health information technology and medical liability risks -- Chapter 17. Improving safety through enterprise risk management -- Chapter 18. Managing HIT contract process for patient safety -- Chapter 19. Improving safety of medical device use through training.
  • Digital
    [prepared by V.K. Lepakhin].
    Digital : WHO2002
    Briefly covers the importance of voluntary reporting on adverse drug reactions (ADR). Highlights include why pharmacovigilance is needed in every country, how ADRs can influence labelling, and prevent new medicine tragedies from developing.
  • Digital
    Shayne C. Gad.
    Digital : CRCnetBASE2012
    "This book covers the regulatory required evaluation and study of the potentially adverse pharmacological effects of new drugs, from the general regulatory requirements to the specific studies that must be done and how they are performed and interpreted. Based on more than 30 years of direct experience, the author describes tricks and practical insights for making studies work and understanding why they don't. The second edition includes current regulations (US FDA and international especially Europe and Japan) and updated test methods, interpretation, and science"--Provided by publisher.
  • Digital
    edited by Antony Bryant, Kathy Charmaz.
    Digital : SAGE2007
    Grounded theory in historical perspective : an epistemological account / Antony Bryant, Kathy Charmaz -- The discovery of grounded theory in practice : the legacy of multiple mentors / Eleanor Krassen Covan -- Living grounded theory : cognitive and emotional forms of pragmatism / Susan Leigh Star -- Doing formal theory / Barney G. Glaser -- On solid ground : essential properties for growing grounded theory / Phyllis Noerager Stern -- From the sublime to the meticulous : the continuing evolution of grounded formal theory / Margaret H. Kearney -- Orthodoxy vs. power : the defining traits of grounded theory / Jane C. Hood -- Grounding categories / Ian Dey -- The development of categories : different approaches in grounded theory / Udo Kelle -- Abduction : the logic of discovery of grounded theory / Jo Reichertz -- Sampling in grounded theory / Janice M. Morse -- Asking questions of the data : memo writing in the grounded theory tradition / Lora Bex Lempert -- The coding process and its challenges / Judith A. Holton -- Making teams work in conducting grounded theory / Carolyn Wiener -- Teaching grounded theory / Sharlene Nagy Hesse-Biber -- The evolving nature of grounded theory method : the case of the information systems discipline / Cathy Urquhart -- Grounded theorizing using situational analysis / Adele E. Clarke, Carrie Friese -- What can grounded theorists and action researchers learn from each other? / Bob Dick -- Feminist qualitative research and grounded theory : complexities, criticisms, and opportunities / Virginia L. Olesen -- Accommodating critical theory / Barry Gibson -- Grounded theory and racial/ethnic diversity / Denise O'Neil Green [and others] -- Advancing ethnographic research through grounded theory practice / Stefan Timmermans, Iddo Tavory -- Grounded theory and reflexivity / Katja Mruck, Günther Mey -- Mediating structure and interaction in grounded theory / Bruno Hildenbrand -- Rational control and irrational free-play : dual-thinking modes as necessary tension in grounded theorizing / Karen Locke -- Research as pragmatic problem-solving : the pragmatist roots of empirically-grounded theorizing / Jörg Strübing.
  • Print
    edited by Norman K. Denzin, Yvonna S. Lincoln.
    Print2011
    Status: Not Checked OutLane Catalog Record
    The editors and contributors address issues of social justice and examine how people's struggles can inform public issues and in turn be transformed into social policy. Their writings are underpinned by a critical framework, and they are committed to addressing issues of inequality. As with previous editions, their aim is to show how the practices of qualitative research can effect change in the world in positive ways.--From publisher description.
  • Digital
    [edited by] Liane S. Feldman, Conor P. Delaney, Olle Ljungqvist, Francesco Carli.
    Digital : Springer2015
    Introduction to Enhanced Recovery Programs: A Paradigm Shift in Perioperative Care -- Section I: The Science of Enhanced Recovery: Building Blocks for your Program -- Peroperative Education -- Medical Optimization and Prehabilitation -- Preoperative Fasting and Carbohydrate Treatment -- Bowel Preparation: Always, Sometimes, Never? -- The Role of the Anesthesiologist in Reducing Surgical Stress and Improving Recovery -- Prevention of Hypothermia -- Prevention of Postoperative Nausea and Vomiting -- Thromboprophylaxis -- Surgical Site Infection Prevention -- Fluid Management -- Postoperative Ileus: Prevention and Treatment -- Choosing Analgesia to Facilitate Recovery -- Early Nutrition and Early Mobilization: Why They Are Important and How to Make it Happen -- Management of Tubes, Drains, and Catheters -- Hospital Recovery and Full Recovery -- Section II: Creation and Implementation of an Enhanced Recovery Program -- Overcoming Barriers to the Implementation of an Enhanced Recovery After Surgery Program -- Introducing Enhanced Recovery Programs into Practice: Lessons Learned from The ERAS® Society Implementation Program -- Enhanced Recovery Programs: Making the Business Case -- Audit: Why and How -- Why Add an ERP to a Laparoscopic Case: The Colorectal Experience -- Section III: Examples of Enhanced Recovery Programs -- Enhanced Recovery Programs for Colorectal Surgery: University Hospitals Case Medical Center -- Enhanced Recovery Programs for Colorectal Surgery: The Guilford: (UK) Experience -- Setting up an Enhanced Recovery Program Pathway for Bariatric Surgery: Current Evidence into Practice -- Enhanced Recovery Pathways in Hepato-pancreato-biliary Surgery -- Enhanced Recovery Programs for Upper Gastrointestinal Surgery: How I Do It -- Department-Wide Implementation of an Enhanced Recovery Pathway -- The ERAS® Society -- SAGES SMART Enhanced Recovery Program.
  • Digital
    Nguyen, N.; Scott-Conner, Carol E. H.; Soper, Nathaniel J.
    Digital : SpringerFulltext v. 1
    Digital : SpringerFulltext v. 2
    V. 1. Basic laparoscopy and endoscopy / Nathaniel J. Soper and Carol E.H. Scott-Conner, editors -- v. 2. Advanced laparoscopy and endoscopy / Ninh T. Nguyen and Carol E.H. Scott-Conner, editors.
  • Digital
    Ninh T. Nguyen, editor-in-chief ; Eric J. DeMaria, Sayeed Ikramuddin, Matthew M. Hutter, editors.
    Digital : Springer2008
  • Digital
    Carol E.H. Scott-Conner, editor ; with a foreword by David W. Rattner.
    Digital : Springer2006
    Print2006
  • Digital
    Matthew Kroh, Kevin M. Reavis, editors.
    Digital : Springer2016
    Surgical Endoscopy -- A Historical Perspective -- Endoscopic Tools -- Instruments -- Operating Platforms for Surgical Endoscopy -- Endoscopic Energy Sources -- Training in Advanced Endoscopic Procedures -- Endoscopic Management of Bleeding -- Stricture Management- Interventional Options -- Endoscopic Stent Placement and Suturing: Management of Gastrointestinal Anastomotic Leaks -- Endoscopic Treatment of Gastrointestinal Fistulas -- Enteral Access: Percutaneous Endoscopic Gastrostomy, Gastrostomy- Jejunostomy, and Jejunostomy -- Endolumenal GERD Therapies -- Barrett's Esophagus -- Radiofrequency (RF) and Other Ablation Modalities -- Endoscopic Mucosal Resection: Upper Gastrointestinal Tract -- Endoscopic Mucosal Resection: Colon and Rectum -- Endoscopic Submucosal Dissection: Upper Gastrointestinal Tract -- Endoscopic Submucosal Dissection: Colon and Rectum -- Per Oral Endoscopic Myotomy (POEM) -- Endoscopic Interventions for the Thoracic Esophagus- Zenker's and other Diverticula -- Endoscopic Retrograde Cholangiopancreatography (ERCP) -- Advanced ERCP: Cholangioscopy and through the Scope Imaging -- Interventional Endoscopic Ultrasound -- Hybrid Laparoscopic and Endoscopic Techniques: Upper Gastrointestinal Tract -- Hybrid Laparoscopic and Endoscopic Techniques: Colon and Rectum -- Primary Endoscopic Treatments for Morbid Obesity -- Endoscopic Revision Procedures after Bariatric Surgery -- Natural Orifice Trans-lumenal Endoscopic Surgery (NOTESTM) -- Future Directions for Endoscopic Operations. .
  • Digital
    Steven C. Stain, Aurora D. Pryor, Phillip P. Shadduck, editors.
    Digital : Springer2016
  • Digital
    Brian P. Jacob, David C. Chen, Bruce Ramshaw, Shirin Towfigh, editors.
    Digital : Springer2016
    Primary Groin Pain -- Musculoskeletal anatomy of groin pain -- Neuroanatomy of groin pain -- History: High yield questions to the patient as part of the history/intake -- Physical Examination: Highly sensitive and specific exam findings -- Inguinal Hernia, Femoral Hernia -- Non-Hernia Causes: Adductor Tendinitis, Osteitis Pubis, Epididymitis, Varicocele, Referred Pain (from hip (e.g., labral tear), back (e.g., radiculopathy, sacroiliitis, ankylosing spondylitis)) -- Sports Hernia -- Chronic pelvic pain in women (endometriosis, pelvic floor dysfunction, round ligament syndrome or masses, ovarian cyst disease, occult hernias) -- Occult Hernias: Typical presentation, symptoms, exam findings, radiologic evaluation -- Secondary Groin Pain -- Causes of Pain from Anterior Repair -- Causes of Pain from Posterior Repair -- Algorithm for Pain Management -- Pharmacologic Management -- Interventional Procedures: Nerve block, epidurals, ablation, neurostimulators -- Radiologic findings of mesh and meshoma -- Dermatomal Mapping: Pre/post-operative assessment -- Quantitative Sensory Testing (QST) -- Management of Recurrence -- Open Triple Neurectomy vs selective neurectomy -- Laparoscopic Triple Neurectomy -- Meshoma Removal (Lap and open) -- Treatment of Orchialgia -- Selected Topics -- Prevention of Pain: Open Technique (include mesh-specific tips) -- Prevention of Pain: Laparoscopic Technique (include technical tips) -- Prophylactic Neurectomy versus Pragmatic Neurectomy -- Selective Neurectomy versus Triple Neurectomy -- Patient Narratives -- Emerging patient and provider care communities (social media for patients with groin pain and for providers who care for patients with groin pain) -- Value-based clinical quality improvement- learning to improve the value of treating patients with groin pain -- Team based approach for treating patients with chronic groin pain.
  • Digital
    Brian P. Jacob, MD, FACS, Mount Sinai School of Medicine, NY, USA, Bruce Ramshaw, MD, FACS, Transformative Care Institute, Daytona Beach, FL, USA, editors.
    Digital : Springer2013
    The SAGES Manual of Hernia Repair will serve as a state-of-the-art resource for hernia surgeons and residents alike who are interested in the rapidly evolving area of abdominal wall hernia repair. This manual captures and summarizes the current trends in the field, as well as describing the new ideas, programs, and strategies regarding hernia repair. Through a unique section called Current Debates in Inguinal Hernia Repair, this volume also provides readers an overview of the current opinions on many of the ongoing debates of this time period. Furthermore, the manual is lavishly illustrated, containing an array of instructional charts and photographs, and is authored by a panel of experts in hernia repair.Comprehensive and easily accessible, The SAGES Manual of Hernia Repair is a portable reference that will be of great value to all practicing surgeons and residents working in the field of abdominal wall hernia repair.
  • Digital
    David S. Tichansky, John Morton, Daniel B. Jones, editors.
    Digital : Springer2012
  • Digital
    Carol E.H. Scott-Conner, editor ; José E. Torres, Nate Thepjatri, case editors.
    Digital : Springer2008
  • Digital
    Liane Feldman, Pascal Fuchshuber, Daniel B. Jones, editors.
    Digital : Springer2012
    Part 1. Fundamentals of Surgical Energy -- Evolutions and Revolutions in Surgical Energy / Steven D. Schwaitzberg -- Fundamentals of Electrosurgery -- Part I: Principles of Radiofrequency Energy for Surgery / Malcolm G. Munro -- Fundamentals of Electrosurgery -- Part II: Thermal Injury Mechanisms and Prevention / L. Michael Brunt -- The Art and Science of Monopolar Electrosurgery / C. Randle Voyles -- Bipolar Electrosurgical Devices / Chan W. Park and Dana D. Portenier -- Electrosurgical Energy in Gastrointestinal Endoscopy / Brian J. Dunkin and Calvin D. Lyons -- Ultrasonic Energy Systems / James G. Bittner, J. Esteban Varela and Daniel Herron -- Cavitron Ultrasonic Surgical Aspirator / James S. Choi -- Principles and Safety of Radiofrequency and Cryo Ablation / Pascal R. Fuchshuber -- Principles and Safety of Microwave Ablation / Ryan Z. Swan and David A. Iannitti -- Surgical Energy Systems in Pediatric Surgery / Gretchen Purcell Jackson -- Integration of Energy Systems with Other Medical Devices / Stephanie B. Jones and Marc A. Rozner -- How to Report Adverse Events Related to the Use of Energy Devices in the Operating Room / Charlotte L. Guglielmi -- Part 2. Enrichment Chapters -- Hands-On Station: Fundamentals and Safety of Radiofrequency Electrosurgery / Malcolm G. Munro -- Hands-on Station: Art and Science of Monopolar Electrosurgery - Case Studies of Metal-to-Metal Arcing and Single Port Cannula Surgery / C. Randle Voyles -- Hands-on Station: Thermal Spread with Bipolar Electrosurgery / Dean Mikami -- Hands-on Station: Ultrasonic Energy Devices / Dana D. Portenier -- Hands-on Station: Cavitron Ultrasonic Surgical Aspirator (CUSA) and Argon Beam Device / James S. Choi -- Hands-on Station: Radiofrequency Ablation / Pascal R. Fuchshuber -- Hands-on Station: Microwave Devices / Ryan Z. Swan and David A. Iannitti -- Hands-on Station: Effects of Monopolar and Bipolar Electrosurgery on Cardiovascular Implantable / Electrical (Pacemakers or Implanted Cardioverter Defibrillator) Devices / Marc A. Rozner and Stephanie B. Jones -- Hands-on Station: Radiofrequency Electrosurgery in Gastrointestinal Endoscopy / Jeffrey W. Hazey.
  • Digital
    edited by S. Hayat and A. Ahmad.
    Digital : Springer2007
  • Digital
    volume editors, Antoon J.M. Ligtenberg, Enno C.I. Veerman.
    Digital : Karger2014
    Anatomy, biogenesis, and regeneration of salivary glands / Holmberg, K.V.; Hoffman, M.P. -- Salivary secretion : mechanism and neural regulation / Proctor, G.B.; Carpenter, G.H. -- Salivary pellicles / Lindh, L.; Aroonsang, W.; Sotres, J.; Arnebrant, T. -- Antimicrobial defense systems in saliva / Nieuw Amerongen, A.V.; van't Hof, W.; Ligtenberg, A.J.M.; Veerman, E.C.I. -- Saliva and wound healing / Veerman, E.C.I.; Ligtenberg, A.J.M.; Brand, H.S. -- Role of saliva in oral food perception / Neyraud, E. -- Lubrication / Yakubov, G.E. -- Saliva diagnostics : utilizing oral fluids to determine health status / Schafer, C.A.; Schafer, J.J. ; Yakob, M.; Lima, P.; Camargo, P.; Wong, D.T.W. -- The use of saliva markers in psychobiology : mechanisms and methods / Bosch, J.A. -- Xerostomia / Delli, K.; Spijkervet, F.K.L.; Kroese, F.G.M.; Bootsma, H.; Vissink, A. -- Drooling / Silvestre-Donat, F.J.; Silvestre-Rangil, J. -- Salivary gland diseases : infections, sialolithiasis, and mucoceles / Delli, K.; Spijkervet, F.K.L.; Vissink, A.
  • Digital
    Jacobo Limeres Posse, Pedro Diz Dios, Crispian Scully.
    Digital : ScienceDirect2017
    "Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses.Stipulates the defensive roles of saliva, an important topic not previously reviewed in-depth in literature. Provides awareness that saliva also transmits infectious agents that can produce serious or even lethal diseases. Gives understanding that kissing may be an at-risk practice"-- Provided by publisher.
  • Print
    edited by David T. Wong.
    Print2008
    Status: Not Checked OutLane Catalog Record
  • Digital
    William C. Faquin, Celeste N. Powers ; foreword by Mary K. Sidaway.
    Digital : Springer2008
  • Digital
    Eugene N. Myers, Robert L. Ferris (eds.).
    Digital : Springer2007
  • Digital
    volume editors, Patrick J. Bradley, David W. Eisele.
    Digital : Karger2016
    Classification of salivary gland neoplasms / Bradley, P.J -- Frequency and histopathology by site, major pathologies, symptoms and signs of -- Salivary gland neoplasms / Bradley, P.J -- Molecular pathology and biomarkers / Ha, P.K, Stenman, G -- Evaluation : imaging studies / Kontzialis, M., Aygun, N., Glastonbury, C.M -- Evaluation : fine needle aspiration cytology, ultrasound-guided core biopsy and -- Open biopsy techniques / Howlett, D., Triantafyllou, A -- Nerve monitoring / Guntinas-Lichius, O., Eisele, D.W -- Surgery for benign salivary neoplasms / Gillespie, M.B., Iro, H -- Recurrent benign salivary gland neoplasms / Witt, R.L., Nicolai, P -- Prognostic scoring for malignant salivary gland neoplasms / Vander Poorten V., Guntinas-Lichius, O -- Surgery for primary malignant parotid neoplasms / Deschler D.G., Eisele, D.W -- Metastatic cancer to the parotid / Clark, J., Wang, S -- Surgery for malignant submandibular gland neoplasms / Silver, N.L., Chinn, S.B., Bradley, P.J., Weber, R.S -- Surgery for malignant sublingual and minor salivary gland neoplasms / Bradley, P.J., Ferris, R.L -- Facial reconstruction and rehabilitation / Guntinas-Lichius, O., Genther, D.J., Byrne, P.J -- Management of regional metastases of malignant salivary gland neoplasms / Medina, J., Zbären, P., Bradley, P.J -- Indications for salivary gland radiotherapy / Thomson, D.J., Slevin, N.J., Mendenhall, W.M -- Chemotherapy and targeted therapy / Sen, M., Prestwich, R -- Management of inoperable malignant neoplasms / Kiess, A.P., Quon, H -- Management of recurrent malignant salivary neoplasms / Richmon, J.D., Quon, H -- Salivary gland neoplasms in children and adolescents / Bradley, P.J., Eisele, D.W -- Distant metastases and palliative care / Glazer, T.A., Shuman, A.G -- Quality of life after salivary gland surgery / Wax, M.K., Talmi, Y.P -- Salivary gland neoplasms: future perspectives / Eisele, D.W., Bradley, P.J.
  • Digital
    volume editors, A.S. Tucker, I. Miletich.
    Digital : Karger2010
    Introduction to salivary glands : structure, function, and embryonic development / Miletich, I. -- Salivary gland adaptations : modification of the glands for novel uses / Tucker, A.S. -- Genetic regulation of salivary gland development in drosophila melanogaster / Pirraglia, C. ; Myat, M.M. -- Extracellular matrix and growth factors in salivary gland development / Sequeira, S.J. ; Larsen, M. ; DeVine, T. -- Lumen formation in salivary gland development / Wells, K.L. ; Patel, N. -- Epithelial stem/progenitor cells in the embryonic mouse submandibular gland / Lombaert, I.M.A. ; Hoffman, M.P. -- Salivary gland regeneration / Carpenter, G.H. ; Cotroneo, E. -- Salivary gland disease / Thomas, B.L. ; Brown, J.E. ; McGurk, M.
  • Digital
    edited by Heide Schatten and Abraham Eisenstark.
    Digital : Springer Protocols2007
    Quantitative, multiplexed detection of salmonella and other pathogens by Luminex xMAP suspension array / Sherry A. Dunbar and James W. Jacobson -- Detection of salmonella by bacteriophage felix 01 / Jonathan C. Kuhn -- Physical mapping of salmonella genomes / Shu-Lin Liu -- Cloth-based hybridization array system for the identification of antibiotic resistance genes in salmonella / Burton W. Blais and Martine Gauthier -- Genome-based identification and molecular analysee of pathogenicity islands and genomic islands in Salmonella enterica / Michael Hensel -- Determination of the gene content of salmonella genomes by microarray analysis / Steffen Porwollik and Michael McClelland -- In vivo excision, cloning, and broad-host-range transfer of large bacterial DNA segments using VEX-capture / James W. Wilson and Cheryl A. Nickerson -- Amplified fragment length polymorphism analysis of Salmonella enterica / Ruiting Lan and Peter R. Reeves -- Salmonella phages and prophages : genomics and practical aspects / Andrew M. Kropinski ... [et al.] -- Salmonella typhimurium phage typing for pathogens / Wolfgang Rabsch -- Salmonella phages examined in the electron microscope / Hans-W. Ackermann -- Applications of cell imaging in salmonella research / Charlotte A. Perrett and Mark A. Jepson -- Analysis of kinesin accumulation on salmonella-containing vacuoles / Audrey Dumont ... [et al.] -- Magnesium, manganese, and divalent cation transport assays in intact cells / Michael E. Maguire -- Methods in cell-to-cell signaling in salmonella / Brian M. M. Ahmer ... [et al.] -- Development of salmonella strains as cancer therapy agents and testing in tumor cell lines / Abraham Eisenstark ... [et al.] -- Further resources for molecular protocols in salmonella research / Abraham Eisenstark and Kelly K. Edwards.
  • Digital
    edited by Heide Schatten, Abraham Eisenstark.
    Digital : Springer Protocols2015
    Luminex® multiplex bead suspension arrays for the detection and serotyping of Salmonella spp / Sherry A. Dunbar [and 4 others] -- Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle / Dora Kaloyanova [and 3 others] -- Determination of antimicrobial resistance in Salmonella spp / Belgode N. Harish and Godfred A. Menezes -- Red-mediated recombineering of Salmonella enterica genomes / Frederik Czarniak and Michael Hensel -- A method to introduce an internal tag sequence into a Salmonella chromosomal gene / Weidong Zhao and Stéphane Méresse -- Generation and use of site-directed chromosomal cyaA' translational fusions in Salmonella enterica / Francisco Ramos-Morales [and 3 others] -- Detection of antimicrobial (poly)peptides with acid urea polyacrylamide gel electrophoresis followed by Western immunoblot / Edith Porter [and 3 others] -- Detecting non-typhoid Salmonella in humans by enzyme-linked immunosorbent assays (ELISAs) : practical and epidemiological aspects / Katrin G. Kuhn [and 3 others] -- Study of the Stn protein in Salmonella; a regulator of membrane composition and integrity / Masayuki Nakano [and 4 others] -- Development of a bacterial nanoparticle vaccine / Carlos Gamazo [and 4 others] -- Direct attachment of nanparticle cargo to Salmonella typhimurium membranes designed for combination bacteriotherapy against tumors / Robert Kazmierczak [and 3 others] -- Applications of microscopy in Salmonella research / Layla M. Malt [and 3 others] -- Live cell imaging of intracellular Salmonella enterica / Alexander Kehl and Michael Hensel -- In vitro modeling of gallbladder-associated Salmonella spp. colonization / Geoffrey Gonzalez-Escobedo and John S. Gunn -- Salmonella phages and prophages : genomics, taxonomy, and applied aspects / Andrea I. Moreno Switt [and 6 others].
  • Print
    Print2009
    Status: Not Checked OutLane Catalog Record
    1. Introduction -- 2. Differences in the nature of chicken meat production and the implications for salmonella and campylobacter -- 3. Review of available scientific information on control of salmonella and campylobacter : occurrence and challenges, and state of the science -- 4. Examples of possible interventions for hazard reduction -- 5. Evaluation of likey outcomes of specific interventions -- 6. Development of a Web-based risk-management tool -- 7. Summarized considerations of CCFH request -- 8. References -- Appendix.
  • Digital
    Katharine Michelle Ng.
    Digital2014
    The human intestine is home to a dense community of commensal microbes that have co-evolved with humans for millions of years. In the absence of disturbance, this community modulates gut homeostasis and mounts a state of colonization resistance against enteric pathogens. This is generally thought to occur through highly efficient resource partitioning as well as the induction and modulation of inflammation and antimicrobial defenses. Profound disturbance of the community, often by way of antibiotic treatment, leads to disruption of colonization resistance. In both humans and animal models, recent antibiotic use is associated with increased susceptibility to several pathogens, including Salmonella typhimurium and Clostridium difficile. This dissertation focuses on understanding the specific mechanisms employed by Salmonella typhimurium during post-antibiotic expansion in the intestine. Chapter 1 provides an introduction to Salmonella as well as to the microbiota and the five phases of microbiota-pathogen interactions. Chapter 2 details a specific strategy utilized by S. typhimurium to expand in the gut, which involves the catabolism of the microbiota-liberated mucosal carbohydrates sialic acid and fucose. The work in Chapter 3 addresses some of the potential applications and questions that have resulted from this finding. Chapter 4 concludes with a discussion of future directions for modulating resistance to pathogens, both with respect to this work as well for the field at large.
  • Digital
    Carlos A. Ball.
    Digital : OSO2014
    This text brings together historical, social science, and legal considerations to comprehensively respond to the objections to same-sex marriage that are based on the need to promote so-called 'responsible procreation' and child welfare.
  • Digital
    Ricardo Ramina, Paulo Henrique Pires Aguiar, Marcos Tatagiba, editors.
    Digital : Springer2008
  • Digital
    Ricardo Ramina, Paulo Henrique Pires Aguiar, Marcos Tatagiba, editors.
    Digital : Springer2014
    This second edition of Samii's Essentials in Neurosurgery contains revised and updated versions of chapters from the first edition plus contributions on new topics written by leading neurosurgeons who were trained by Professor Madjid Samii in Hannover, Germany. Almost all fields of neurosurgery are covered. The authors follow the traditional principles of Samii's philosophy in the diagnosis and management of various neurosurgical pathologies, while presenting their own personal experiences. The extensively illustrated texts document clearly how cutting-edge technology in neurosurgery is being applied in new approaches and techniques. This book will greatly assist neurosurgeons, ENT surgeons, neuroradiologists, neurologists, and neurophysiotherapists in their everyday practice.
  • Digital
    [edited by] Shein-Chung Chow, Jun Shao, Hansheng Wan.
    Digital : CRCnetBASE2008
    Considerations prior to sample size calculation -- Comparing means -- Large sample tests for proportions -- Exact tests for proportions -- Tests for goodness-of-fit and contingency tables -- Comparing time-to-event data -- Group sequential methods -- Comparing variabilities -- Bioequivalence testing -- Dose response studies -- Microarray studies -- Bayesian sample size calculation -- Nonparametrics -- Sample size calculation in other areas.
  • Digital
    Zhen (Peggy) Yao.
    Digital2010
    The conformational selection model is emerging as one of the best options to model protein flexibility in ligand binding. According to this model, a protein spans an ensemble of rapidly inter-converting folded conformations and a ligand selects the most favorable conformations to bind to from this ensemble. However, only a small number of folded conformations can be obtained experimentally (e.g., from X-ray crystallography, NMR spectrometry, or cryo-electron microscopy), while existing computational techniques (e.g., Molecular Dynamics and Monte-Carlo simulation) are often too expensive to sample conformations broadly distributed across the folded state of a protein. This dissertation focuses on designing new computational methods to efficiently explore the folded state of a protein using kino-geometric sampling approach, i.e., an approach that only considers kinematic constraints (fixed bond lengths and angles) and geometric constraints (no collision of atoms modeled as hard spheres). This approach heavily relies on the fact that in a folded state protein atoms are densely packed. The kino-geometric approach is first applied to loop sampling, where the goal is to explore the conformation space of a loop between two secondary structure elements (helices and/or strands) assuming that the conformation of the rest of the protein is fixed and given as input. Next, it is applied to the considerably more complex problem of sampling folded conformations of an entire protein. In both cases, the proposed methods are validated by showing that the kino-geometric sampler is able to produce a relatively small distribution of conformations (of a loop in the first case, and of an entire protein in the second case) that contains one or more conformations at small Root Means Square Deviation (RMSD) from a "target" conformation. This target conformation is not given to the kino-geometric sampler; therefore, the sampling process is not biased toward this conformation. The main computational difficulties in sampling folded protein conformations result from the large dimensionality of the conformation space and the very small relative volume of the folded subspace. While the small volume of the folded subspace is a necessary precondition for any sampling-based exploration method to work (otherwise a prohibitive number of samples would be required to adequately represent the subspace), it also makes it hard to sample conformations that fall into that subspace. The problem is analogous to looking for a pin in a haystack. For loop conformation sampling, a kino-geometric sampling method based on constraint prioritization is proposed. The idea is to break the loop into several pieces and, for each piece, to achieve the most restrictive constraints (geometric or kinematic) first. The method was tested on loops varying in length from 5 to 25 residues. Its combination with a pre-existing functional site prediction software (FEATURE) makes it possible to compute and recognize calcium-binding loop conformations. To sample folded conformations of an entire protein, this dissertation proposes a set of algorithms integrated into a sampler called KGS. Inspired by two previous kino-geometric samplers (ROCK and FRODA), KGS explores the folded state of a protein by expanding a distribution of conformations from an input folded conformation (usually extracted from the Protein Data Bank). Like ROCK and FRODA, it avoids unfolding the protein by selecting stable hydrogen bonds (H-bonds) and integrates them as additional kinematic constraints. But H-bonds result in a protein kinematic model containing many (often several dozens) interdependent closed kinematic cycles. These cycles considerably complicate sampling operations, as the rotatable dihedral angles can no longer be perturbed independently. The contributions of KGS are threefold: 1. It uses a Jacobian-based method to simultaneously deform many cycles of a protein kinematic structure without breaking them. This method is faster than that of ROCK, and allows deformation steps of greater amplitude than FRODA. 2. KGS embeds a new non-biased diffusive strategy that expands quickly away from the input conformation and progressively samples conformations more and more densely distributed over the folded state. 3. To predict H-bond stability, KGS uses a protein-independent model where energetic contribution is only one predictor among others. This model, trained on molecular dynamics data, has been shown to be 20% more accurate than models based on energy alone. Experiments show that KGS can sample functional (binding) conformations of a protein, given a non-functional (non-binding) one, even when the RMSD between the two conformations is large. This work indirectly demonstrates that kinematic and geometric constraints provide a good characterization of the folded state of a protein, despite the fact that they only implicitly and partially encode electrostatic and van der Waals (vdW) energy terms. On the other hand, it is much faster to handle these kino-geometric constraints computationally than energy functions, which are made of many terms.
  • Digital
    International Commission on Radiation Units and Measurements.
    Digital : HighWire2006
  • Digital
    M. Köhl, S.S. Magnussen, M. Marchetti.
    Digital : Springer2006
  • Digital
    [edited by] K. Frank Austen ... [et al.].
    Digital : Ovid2001
    v. 1. Recognition : innate and adaptive immunity -- Effector mechanisms : innate and adaptive -- Primary immunodeficiencies -- Proliferation disorders of immunologic cells -- v. 2. Systemic diseases -- Organ-specific diseases -- Allergic diseases -- Evasion, activation and ineffective immunity -- Transplantation -- Therapeutic immunology.
  • Digital
    edited by Martin A. Samuels, Allan H. Ropper.
    Digital : Ovid2010
    Print2010
    Coma, head trauma, and spinal cord injury / Galen V. Henderson -- Epilepsy / Edward B. Bromfield and Barbara A. Dworetzky -- Dizziness / Robert W. Baloh -- Back and neck pain / Allan H. Ropper -- Sleep disorders / Milena Pavlova -- Neurooncology / Patrick Y. Wen and Santosh Kesari -- Multiple sclerosis and other demyelinating diseases / Maria K. Houtchens and David M. Dawson -- Motor neuropathies and peripheral neuropathies / Anthony A. Amato -- Neuromuscular junction disorders and myopathies / Anthony A. Amato -- Chronic pain / Robert D. Helme -- Headache and facial pain / Elizabeth Loder and Paul Rizzoli -- Stroke and cerebrovascular disorders / Steven K. Feske -- Movement disorders / Lewis Sudarsky -- Behavioral neurology and dementia / Kirk R. Daffner and David A. Wolk -- Neuroophthalmology / Marc J. Dinken and Don C. Bienfang -- Toxic and metabolic disorders / Martin A. Samuels -- Infections of the central nervous system / Tracey A. Cho.
  • Print
    editors, Martin A. Samuels, Allan H. Ropper.
    Print2017
    Status: Not Checked OutLane Catalog Record
    Coma, head trauma, and spinal cord injury / Galen V. Henderson and Matthew B. Bevers -- Epilepsy / Rani A. Sarkis and Barbara Dworetzky -- Dizziness / Gregory T. Whitman and Robert W. Baloh -- Back and neck pain / Allan H. Ropper -- Sleep disorders / Milena Pavlova -- Cancer neurology / Eudocia Quant Lee and Patrick Y. Wen -- Multiple sclerosis and related disorders / Maria K. Houtchens and James M. Stankiewicz -- Autoimmune disorders / Ivana Vodopivec and Henrikas Vaitkevicius -- Neuromuscular junction disorders and myopathies / Anthony A. Amato and Mohammed Kian Salajegheh -- Motor neuronopathies and peripheral neuropathies / Mohammed Kian Salajegheh and Anthony A. Amato -- Chronic pain / Daniel D. Vardeh -- Headache and facial pain / Paul B. Rizzoli and Elizabeth Loder -- Stroke and cerebrovascular disorders / Henrikas Vaitkevicius and Steven K. Feske -- Movement disorders / Jordan D. Paulson and Lewis R. Sudarsky -- Behavioral and cognitive neurology / Seth A. Gale and Kirk Daffner -- Management of neurologic disorders in resource-limited settings / Aaron L. Berkowitz -- Neuroophthalmology / Robert M. Mallery and Sashank Prasad -- Toxic and metabolic disorders / Shamik Bhattacharyya and Martin A. Samuels -- Infectious diseases / Jennifer Lyons and Tracey A. Cho.
  • Digital
    [edited by] Paul A. Volberding [and others].
    Digital : ClinicalKey2012
    Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care.Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. Diagnose AIDS manifestations confidently by comparing them to full-color clinical images. Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness. Efficiently review essential data through numerous at-a-glance tables. Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings. Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine. The very latest in HIV/AIDS management from global experts with a concise approach and a clinical/practical focus.
  • Digital
    Digital : WHO2015
    Print2015
  • Print
    Jane M. Orient.
    Print2010
    Status: Not Checked OutLane Catalog Record
  • Digital
    edited by Nigel G. Laing.
    Digital : Springer2008
    Print2008
    The sarcomere and sarcomerogenesis / Elisabeth Ehler and Mathias Gautel -- Skeletal muscle alpha-actin diseases / Kathryn N. North and Nigel G. Laing -- Nebulin : a giant chameleon / Katarina Pelin and Carina Wallgren-Pettersson -- Skeletal muscle disease due to mutations in tropomyosin, troponin, and cofilin / Nigel F. Clarke -- Investigations into the pathobiology of thin-filament myopathies / Biljana Ilkovski -- Mouse models for thin filament disease / Mai-Anh T. Nguyen and Edna C. Hardeman -- Thick filament diseases / Anders Oldfors and Phillipa J. Lamont -- Acute quadriplegic myopathy : an acquired "myosinopathy" / Lars Larsson -- Third filament diseases / Bjarne Udd -- The Z-disk diseases / Duygu Selcen and Olli Carpén -- Intermediate filament diseases : desminopathy / Lev G. Goldfarb ... [et al.] -- Muscular integrity : a matter of interlinking distinct structures via plectin / Patryk Konieczny and Gerhard Wiche -- The sarcomere and the nucleus : functional links to hypertrophy, atrophy, and sarcopenia / Mathias Gautel -- Other model organisms for sarcomeric muscle diseases / John Sparrow, Simon M. Hughes, and Laurent Segalat -- Therapeutic approaches for the sarcomeric protein diseases / Kristen J. Nowak.
  • Digital
    Gordon S. Lynch, editor.
    Digital : Springer2011
    Overview of Sarcopenia -- Muscle wasting in cancer and ageing: cachexia versus sarcopenia -- Age-related remodeling of neuromuscular junctions -- Aging related changes motor unit structure and function -- Excitation-contraction coupling regulation in aging skeletal muscle -- Alterations in mitochondria and their impact in aging skeletal muscle -- Skeletal muscle collagen: age, injury and disease -- Nuclear apoptosis and sarcopenia -- Age-related changes in the molecular regulation of skeletal muscle mass -- Genetic variation and skeletal muscle traits: implications for sarcopenia -- Proteomic and biochemical profiling of aged skeletal muscle -- Exercise and nutritional interventions to combat age-related muscle loss -- Reactive oxygen species generation and skeletal muscle wasting, implications for sarcopenia -- Exercise as a countermeasure for sarcopenia -- Role of contraction-induced injury in age-related muscle wasting and weakness -- Role of IGF-1 in age-related loss of skeletal muscle mass and function -- Role of myostatin in skeletal muscle growth and development: implications for sarcopenia -- Role of beta-adrenergic signalling in skeletal muscle wasting: implications for sarcopenia -- Index.
  • Digital
    edited by Dave Cavanagh.
    Digital : Springer Protocols2008
    A pancoronavirus RT-PCR assay for detection of all known coronaviruses / Leen Vijgen ... [et al.] -- Detection of group 1 coronaviruses in bats using universal coronavirus reverse transcription polymerase chain reactions / Leo L.M. Poon and J.S. Malik Peiris -- Detection and sequence characterization of the 3'-end of coronavirus genomes harboring the highly conserved RNA motif s2m / Christine Monceyron Janassen -- RT-PCR detection of avian coronaviruses of galliform birds (chicken, turkey, pheasant) and in a parrot / Francesca Anne Culver, Paul Britton, and Dave Cavanagh -- Detection of group 2a coronaviruses with emphasis on bovine and wild ruminant strains / Mustafa Hasoksuz, Anastasia Vlasova, and Linda J. Saif -- Detection of SARS coronavirus in humans and animals by conventional and quantitative (real time) reverse transcription polymerase chain reactions / J.S. Malik Peiris and Leo L.M. Poon -- Detection of new viruses by VIDISCA / Krzysztof Pyrc ... [et al.] -- Titration of human coronaviruses, HCoV-229E and HCoV-OC43, by an indirect immunoperoxidase assay / Francine Lambert ... [et al.] -- The preparation of chicken tracheal organ cultures for virus isolation, propagation, and titration / Brenda V. Jones and Ruth M. Hennion -- Isolation and propagation of coronaviruses in embryonated eggs / James S. Guy -- Large-scale preparation of UV-inactivated SARS coronavirus virions for vaccine antigen / Yasuko Tsunetsugu-Yokota -- Purification and electron cryomicroscopy of coronavirus particles / Benjamin W. Neuman ... [et al.] -- Production of coronavirus nonstructural proteins in soluble form for crystallization / Yvonne Piotrowski ... [et al.] -- Generating antibodies to the gene 3 proteins of infectious bronchitis virus / Amanda R. Pendleton and Carolyn E. Machamer -- Establishment and characterization of monoclonal antibodies against SARS coronavirus / Kazuo Ohnishi -- Production of monospecific rabbit antisera recognizing nidovirus proteins / Jessika C. Zevenhoven-Dobbe ... [et al.] -- Manipulation of the coronavirus genome using targeted RNA recombination with interspecies chimeric coronaviruses / Cornelis A.M. de Haan ... [et al.] -- Generation of recombinant coronaviruses using vaccinia virus as the cloning vector and stable cell lines containing coronaviral replicon RNAs / Klara Kristin Eriksson, Divine Makia, and Volker Thiel -- Transient dominant selection for the modification and generation of recombinant infectious bronchitis coronaviruses / Maria Armesto ... [et al.] -- Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes / Fernando Almazán, Carmen Galán, and Luis Enjuanes -- Systematic assembly and genetic manipulation of the mouse hepatitis virus A59 genome / Eric F. Donaldson, Amy C.Sims, and Ralph S. Baric -- Identification of sugar residues involved in the binding of TGEV to porcine brush border membranes / Christel Schwegmann-Wessels and Georg Herrler -- Pseudotyped vesicular stomatitis virus for analysis of virus entry mediated by SARS coronavirus spike proteins / Shuetsu Fukushi, Rie Watanabe, and Fumihiro Taguchi.
  • Digital
    by Bernd Sebastian Kamps & Christian Hoffmann (editors); contributing authors, Christian Drosten, Wolfgang Preiser.
    Digital : Flying Publisher2003-
    SARS reference is a medical textbook that provides a comprehensive and up-to-date overview of severe acute respiratory syndrome (SARS).
  • Digital
    Ken Kleinman, Nicholas J. Horton.
    Digital : CRCnetBASE2010
  • Digital
    Ken Kleinman, Nicholas J. Horton.
    Digital : CRCnetBASE2014
    1. Data input and output -- 2. Data management -- 3. Statistical and mathematical functions -- 4. Programming and operating system interface -- 5. Common statistical procedures -- 6. Linear regression and ANOVA -- 7. Regression generalizations and modeling -- 8. A graphical compendium -- 9. Graphical options and configuration -- 10. Simulation -- 11. Special topics -- 12. Case studies.
  • Digital
    Stephen McDaniel.
    Digital : ProQuest Safari2007
  • Digital
    Ron Cody.
    Digital : ProQuest Safari2010
    Character functions -- Perl regular expressions -- Sort functions -- Date and time functions -- Array functions -- Truncation functions -- Descriptive statistics functions -- Mathematical and numeric functions -- Random number functions -- Special functions -- State and ZIP code functions -- Trigonometric functions -- Macro functions -- SAS file I/O functions -- Variable information functions -- Bitwise logical functions.
  • Digital
    [edited by] John C. Hall ; with 35 contributing authors.
    Digital : Ovid2006
    Print2006
  • Digital
    Sandy Summers, Harry Jacobs Summers.
    Digital : OSO2014
    Machine generated contents note: -- Foreword by Echo Heron -- Introduction -- Part One: Dangerous Ignorance: Why Our Understanding of Nursing Matters -- Chapter 1: Who are Nurses and Where Have They Gone? -- Chapter 2: How Nursing's Image Affects Your Health -- Part Two: The Great Divide: The Media versus Real Nursing -- Chapter 3: Could Monkeys Be Nurses? -- Chapter 4: Yes, Doctor! No, Doctor! -- Chapter 5: The Naughtiest Nurse -- Chapter 6: Who Wants Yesterday's Girl? -- Chapter 7: You Are My Angel -- Chapter 8: Winning the Battle-Axe, Losing the War -- Chapter 9: Advanced Practice Nurses: Skilled Professionals or Cut-Rate Physician -- Part Three: Seeking Better Understanding of Nursing-and Better Health Care -- Chapter 10: How We Can All Improve Understanding of Nursing -- Chapter 11: How Nurses Can Improve Their Own Image.
  • Digital
    Richard J. Lewis, Sr.
    Digital : Wiley2012
    "Includes comprehensive hazard information on the substances encountered in the workplace. The objective of the work is to promote safety by providing the most up-to-date hazard information available"--Provided by publisher. "Since its inception in the early 1950's, this book has become the "bible" for those who need to evaluate the hazard of substances used in commerce. The book contains extensive data on approximately 28,000 substances. It is designed to fill the information needs of professionals who must work with and evaluate the hazards of chemicals"--Provided by publisher.
  • Digital
    William Hazen Parsons.
    Digital2013
    Voltage-gated sodium channels (NaV) serve an essential role in physiology. Accordingly, their dysfunction is associated with a number of human diseases and disorders, including epilepsy, cardiac arrhythmias, and chronic pain conditions. Designed by Nature as a chemical weapon, the naturally occurring channel blocker (+)-saxitoxin (STX) can be repurposed as a tool for studying these large integral membrane proteins. Access to new toxin derivatives through de novo synthesis offers a unique strategy to probe NaV structure and function, circumventing key limitations associated with existing methods for studying these proteins. The preparation and electrophysiological evaluation of an expanded library of N21-modified STX analogues is described herein. Characterization of the binding properties of these nanomolar NaV inhibitors has contributed to the development of an enhanced model for the structure of the inner pore of the channel. A select set of STX-fluorophore conjugates that bind reversibly to NaV with submicromolar potency serve as fluorescent markers of channels in living cells to study channel motility in the cell membrane. By contrast, maleimide-conjugated STX derivatives can be engineered to act as irreversible inhibitors of ion conductance when applied to wild-type NaV isoforms. The unique binding behavior of these derivatives has been leveraged to develop a new class of NaV probes for use in live cell imaging experiments and protein profiling studies. Maleimide-toxin conjugates with bioorthogonal reactive groups have been synthesized and can be employed for ligation of visualization and isolation tags to covalently modified channels. Appendage of fluorine-18 to a modified STX affords a probe for studying NaV expression in living subjects. An efficient synthetic route yields a derivative that binds with nanomolar affinity to several NaV isoforms. Biodistribution, autoradiography, and PET-MRI imaging studies demonstrate accumulation of the radiotracer at the site of injury in a rat model of neuropathic pain. This uptake correlates with the previously reported upregulation of NaV isoforms at this site, validating the utility of this probe as a NaV imaging agent. Collectively, these STX derivatives, uniquely available through chemical synthesis, represent a novel set of molecular probes for studying NaV function in vitro and in vivo.
  • Digital
    James Nickells, Ben Walton.
    Digital : Cambridge2012
    Preparing for the Primary FRCA? Wondering what to expect of the new SBA questions? Help is at hand. This practical book contains 60 single best answer and 120 multiple true/false questions to help you revise for the Primary FRCA MCQ exam. Each question is accompanied by detailed explanations, giving additional information on each topic to enhance revision. SBA and MTF MCQs for the Primary FRCA may be used both for examination practice and as a source of knowledge on many of the key topics in the syllabus. A helpful introductory section gives practical advice on how to approach revision and sitting the exam. From the writing team behind the FRCAQ website (www.frcaq.com), SAQs for the Final FRCA and SBAs for the Final FRCA, this book provides challenging questions and well researched explanations to help you through the Primary FRCA MCQ paper. An invaluable tool for your MCQ exam preparation.
  • Digital
    edited by Amanda Jones.
    Digital : Cambridge2015
  • Digital
    Chinmayee Ratha, Janesh Gupta.
    Digital : Springer2016
    SBA type questions: Antenatal care.- Maternal medical disorders -- Fetal medicine -- Labour and delivery.- Postpartum issues.- Early Pregnancy care.- Gynaecological problems.- Subfertility and endocrinology.- Sexual and reproductive health.- Gynaecological oncology.- Urogynecology and pelvic floor problems.- Core surgical skills and postoperative care.- Surgical procedures -- Clinical governance Single best answers and explanations: Antenatal care.- Maternal medical disorders -- Fetal medicine -- Labour and delivery.- Postpartum issues.- Early Pregnancy care.- Gynaecological problems.- Subfertility and endocrinology.- Sexual and reproductive health.- Gynaecological oncology.- Urogynecology and pelvic floor problems.- Core surgical skills and postoperative care.- Surgical procedures -- Clinical governance .
  • Print
    Print1940-
    Status: Not Checked OutLane Catalog Record
  • Digital
    Yun Chen.
    Digital2013
    Continuous wireless monitoring of in vivo biopotential, biochemical, and biomechanical properties has the potential to yield breakthroughs in our understanding of human health and disease. In particular, current technology does not yet allow us to do so at micron (i.e., cellular) scales. We look to create a scalable system of chronically implantable passive sensors with a wireless detection platform to individually address and continuously monitor them. Scaling down the size of resonant sensors poses significant challenges for passive wireless detection. In particular, inherently higher resonant frequencies at smaller sizes push our operation into regimes where traditional approaches fail. Two schemes based on power reflection distortion (PRD) and group delay distortion (GDD) are proposed to operate over a wide range of frequencies. They are shown to be capable of operating in high frequency regimes near and above the readout circuit self-resonance. In addition, we describe a generic finite-difference time-domain (FDTD) framework for analyzing electromagnetic (EM) wave propagation and scattering in an anatomically realistic human phantom with an inhomogeneous dispersive model. Interactions with implantable resonant sensors are studied within this framework. We demonstrate a wireless real-time monitoring system with passive, flexible sensors, which scale down to unprecedented dimensions of 1x1x0.1 cubic mm. This level of scaling is enabled by the presented GDD detection scheme, which overcomes the operating frequency limits of traditional strategies and exhibits insensitivity to lossy tissue environments. We apply this system to capture human pulse waveforms in real-time as well as to continuously monitor in vivo intracranial pressures with sensors down to 2.5x2.5x0.1 cubic mm in proof-of-concept mice studies. Furthermore, printable wireless sensor arrays are introduced and their use in concurrent spatial pressure mapping is shown. Our vision is to extend the passive sensing approach and scale the resonant sensor platform down to intracellular dimensions at the intersection of intracellular delivery limits and integrated circuit fabrication capabilities. We demonstrate a family of 3D multilayer micro-Tag (uTag) structures as a potential platform for resonant tagging and sensing at the cellular level. As a stepping stone towards chronic cellular monitoring, we demonstrate the delivery of uTags into living cells and viability of internalized uTags over a 5-day period. Looking forward, this technology creates exciting opportunities to use remote physiological monitoring as a routine part of biomedical research and patient care. In the future, we foresee that such monitoring will be possible even at the cellular level.
  • Digital
    Michelle René Davison.
    Digital2013
    Microbial diversity can be queried at several scales within natural environments. On a macroscopic scale, microbial communities are capable of incredible feats: from colonizing the most inhospitable habitats imaginable, to creating ancient stromatolites, or living in intimate symbioses with the human body, inside and out. These complex microbial assemblages are comprised of different microscopic populations, which interact as a whole to stabilize the community ecosystem: selective evolutionary pressures work to shape each population, exquisitely adapting it to succeed in the current environmental conditions. In turn, these populations are comprised of millions of individual cells, each struggling to survive a variety of environmental stressors, to outcompete their closely-related neighbours, and carve out a distinct niche. Single cells wage constant war against predators such as viruses, which exist in large numbers and can effect entire populations, and ultimately the community as a whole. With such a range of complexity within a microbial community, it is essential to view microbial diversity through several tiers, in order to achieve a more complete picture. Only when diversity is viewed from several hierarchical levels, can the connections be made between the biology that is occurring on very fine scales and its effect on the entire system. Thus, this thesis has characterized microbial diversity in the hot spring microbial mats of Yellowstone National Park at multiple scales. There are several reasons why the microbial mats represent the ideal model system in which to query microbial diversity (Chapter 1). The evolution and adaptation of thermophilic Synechococcus sp. across a temperature gradient is queried by the creation of a targeted deep sequencing dataset, revealing statistically significant SNPs that correlate with thermal adaptation (Chapter 2). A second targeted deep sequencing dataset of 90 loci was generated to investigate the microdiversity present between two closely related thermophilic Synechococcus species, confirming the presence of micro-niches in stabilizing diversity across several years (Chapter 3). Successful gene amplification of the T1B CRISPR loci from a single cyanobacterial cell was achieved with the goal of investigating diversity at the single cell level (Chapter 4). Lastly, host-virus co-evolution is characterized by creation of a virome and a novel pipeline to assemble and analyze viral sequences: matching potential host-viral pairs by using CRISPR spacers (Chapter 5).
  • Digital
    edited by Jianguo Wu ... [et al.].
    Digital : Springer2006
  • Print
    edited by Ruth Simmons, Peter Fajans, and Laura Ghiron.
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    Jeffrey Yao, editor.
    Digital : Springer2015
    Scaphoid Anatomy -- Non-operative Management of Non-displaced Acute Scaphoid Fracture -- Acute Scaphoid Fracture Management: Dorsal Approach -- Acute Scaphoid Fractures: Volar Approach -- Arthroscopic-Assisted Management of Acute Scaphoid Fractures -- Treatment of Acute Pediatric Scaphoid Waist Fractures -- Scaphoid Nonunion: Surgical Fixation Without Bone Graft -- Scaphoid Non-union Open Treatment with Distal Radius Bone Graft via Mini Dorsal Approach -- Scaphoid Nonunion: Surgical Fixation with Local Non-vascularized Bone Graft (Open) -- Scaphoid Non-Union Treated with Iliac Crest Structural Autograft -- The Hybrid Russe Graft for the Treatment of Scaphoid Nonunion -- Arthroscopic Grafting and Scapholunate Pinning for Scaphoid Proximal Pole Nonunion -- 1,2 ICSRA for the Management of Proximal Pole Scaphoid Nonunion -- Dorsal Capsular-Based Vascularized Distal Radius Graft for Scaphoid Nonunion -- Scaphoid Nonunion: Surgical Fixation with Vascularized Bone Grafts-Volar Pedicle -- Scaphoid Nonunion: Surgical Fixation with Vascularized Bone Graft-Free Medial Femoral Condyle Graft -- Pediatric Scaphoid Nonunion -- Partial Scaphoidectomy for Unsalvageable Scaphoid Nonunion -- Reconstruction of the Unsalvageable Proximal Pole in Scaphoid Nonunions Utilizing Rib Osteochondral Autograft -- Recalcitrant Proximal Pole Scaphoid Nonunion -- Unsalvageable Scaphoid Nonunion: Implant Arthroplasty -- Scaphoid Nonunion Advanced Collapse: Denervation -- Scaphoid Nonunion Advanced Collapse: Arthroscopic Debridement/Radial Styloidectomy -- Scaphoid Nonunion Advanced Collapse: Capitolunate Arthrodesis -- Scaphoid Nonunion Advanced Collapse: Scaphoid Excision and 4-Corner Arthrodesis -- PRC for Scaphoid Nonunion Advanced Collapse Wrist -- Index.
  • Digital
    edited by Abhay Rane, Jeffrey A. Cadeddu, Mihir M. Desai, Inderbir S. Gill.
    Digital : Springer2013
    Laparoendoscopic Single-Site Surgery (LESS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES) are based on the premise that patients should benefit in terms of recovery time, physical discomfort, pain, and cosmesis if a surgical procedure can be performed without visible scarring. Scar-Less Surgery: NOTES, Transumbilical, and Others is a multi-disciplinary effort which weaves together the surgical aspects of these novel techniques. It is the first comprehensive reference on the subject providing state-of-the-art technical information to both general and urologic surgeons while also highlighting future developments and research needs.
  • Print
    [edited by] N. Cary Engleberg, Victor DiRita, Terence S. Dermody.
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    Moshe Schein, Paul N. Rogers, Ahmad Assalia (editors).
    Digital : Springer2010
  • Digital
    Jay H. Lefkowitch.
    Digital : ClinicalKey2016
    "The 9th Edition brings you fully up to date in the field, with coverage of new diagnostic tools, new information on drug-induced liver injury and cytopathology, and many new high-quality illustrations. Throughout the text, you'll find technical tips, diagnostic clues, and pearls that reflect the extensive experience and insight of the late Dr. Peter Scheuer and internationally renowned author Dr. Jay Lefkowitch, making this new edition your standard bench-side guide to today's liver biopsy diagnosis"--Publisher's description.
  • Digital
    [edited by] Eugene R. Schiff, Michael F. Sorrell, Willis C. Maddrey.
    Digital : Ovid2007
    Printv. 1-2.
    History taking and physical examination for the patient with liver disease -- Laboratory tests -- Liver biopsy and laparoscopy -- Imaging -- Interventional radiology procedures for diagnosis and treatment of hepatobiliary disease -- Endoscopic retrograde cholangiopancreatography -- Physioanatomic considerations -- Bilirubin metabolism and jaundice -- Hepatic histopathology -- Mehanisms of liver injury -- The liver in systemic disease -- Hematologic disorders and the liver -- Nutrition and the liver -- Hepatic fibrosis -- Portal hypertension and nonsurgical management -- Surgical management of portal hypertension -- Renal complications and hepatorenal syndrome -- Pulmonary manifestations of liver disease -- Ascites and spontaneous bacterial peritonitis -- Hepatic encephalopathy -- fulminant hepatic failure -- Gallstone disease: pathogenesis and treatment -- Primary sclerosing cholangitis -- Primary biliary cirrhosis -- Postoperative jaundice -- The hepatitis viruses -- Hepatitis A -- Hepatitis E -- Hepatitis B and D -- Hepatitis C -- Autoimmune hepatitis -- Alcoholic liver disease -- Drug-induced liver disease -- Mechanisms of drug-induced liver injury -- Wilson disease -- Hemochromatosis and iron storage disorders -- a₁-Antitrypsin deficiency -- Porphyrias -- Nonalcoholic fatty liver disease -- Vasucular diseases of the liver -- The liver in circulatory failure -- Benign solid tumors -- Nodular and cystic lesions -- Hepatocellular carcinoma -- Surgical options for the treatment of hepatocellular carcinoma -- Liver disease in infancy and childhood -- The liver in pregnancy -- Liver abscesses -- Parasitic diseases -- Bacterial and systemic infections -- Hepatobiliary manifestations of human immunodeficiency virus -- Granulomas of the liver -- Selection and timing of liver transplantation -- Immunosuppression: the global picture -- The first 6 months following liver transplantation -- The long-term care of transplanted patient -- The surgical options of liver transplantation -- Recurrent disease following liver transplantation -- The role of retransplantation -- Hepatobiliary complications of hematopoietic cell transplantation.
  • Digital
    Mahesh Chandra Agrawal.
    Digital : Springer2012
    Introduction -- The schistosomes -- The snail -- Prevalence in final host -- Immunological studies -- Disease manifestation and pathology -- Parasitological diagnosis -- Immunodiagnosis -- Chemotherapy -- Control -- Laboratory models developed -- Technologies developed.
  • Digital
    Michael Poyurovsky.
    Digital : Cambridge2013
    This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD).
  • Digital
    Phillip G. Janicak, Stephen R. Marder, Rajiv Tandon, Morris Goldman, editors.
    Digital : Springer2014
    "Schizophrenia: Recent Advances in Diagnosis and Treatment is a major addition to the literature, offering practical, comprehensive coverage of diagnosis and treatment options, genetic issues, neuroimaging, long-term management of schizophrenia, and future directions and predictions of how clinical care of schizophrenia will change. The book is divided into five sections. Section 1 summarizes the present state of knowledge about the diagnosis and treatment of schizophrenia. This includes recent changes in the DSM 5 categorization of schizophrenia and its implications for treatment. Section 2 considers recent discoveries into its pathoetiology, including the status of biological markers, genetics and neuroimaging as they relate to diagnosis and potential novel therapeutic approaches. Section 3 explores the optimization of present therapeutic approaches; novel treatments; and management of the substantial risks associated with both the illness and its present therapies. Section 4 discusses progress in the long-term management of schizophrenia, focusing on biological and psychotherapeutic strategies to improve functioning and facilitate recovery. Section 5 considers future directions and predictions of how diagnosis and treatment of schizophrenia will change. An invaluable addition to the field, Schizophrenia: Recent Advances in Diagnosis and Treatment is a definitive resource that will be of great interest to all clinicians caring for patients with schizophrenia."--Publisher's website.
  • Digital
    Matthew M. Kurtz.
    Digital : OSO2015
    Approach -- Course and outcome -- The diagnosis of schizophrenia -- A brief history of the treatment of schizophrenia -- Biological mechanisms -- Psychological factors -- Somatic treatments -- Psychological and psychosocial treatments -- Epilogue : a flight of fancy and the gap between science and practice.
  • Print
    P.J. McKenna.
    Print2007
    Status: Not Checked OutLane Catalog Record
    The cardinal symptoms of schizophrenia -- The clinical pictures of schizophrenia -- The natural history of schizophrenia -- The diagnosis of schizophrenia -- Aetiological factors in schizophrenia -- The neurochemistry of schizophrenia -- The neurodevelopmental theory of schizophrenia -- The psychology and neuropsychology of schizophrenia -- The cognitive neuropsychology of schizophrenia -- Neuroleptic drug treatment -- The management of schizophrenia -- Paraphrenia and paranoia -- Schizoaffective and other atypical psychoses -- Schizophrenia and organic brain disease -- Childhood schizophrenia, autism and Asperger's syndrome -- Schizophrenia and personality.
  • Digital
    C. Raymond Lake.
    Digital : Springer2012
  • Digital
    [edited by] Alfredo Quiñones-Hinojosa.
    Digital : ScienceDirect2012
    Digital : ClinicalKey2012
    V. 1: -- Ensuring Patient Safety in Surgery-First Do No Harm -- Surgical Navigation with Intraoperative Imaging: Special Operating Room Concepts -- Functional Tractography, Diffusion Tensor Imaging, Intraoperative Integration of Modalities, and Neuronavigation -- Intraoperative Neurophysiology: A Tool to Prevent and/or Document Intraoperative Injury to the Nervous System -- Gamma Knife Surgery for Cerebral Vascular Malformations and Tumors -- Cortical and Subcortical Brain Mapping -- Chemotherapy for Brain Tumors -- Current Surgical Management of High-Grade Gliomas -- Surgical Management of Low-Grade Gliomas -- Management of Recurrent Gliomas -- Tumors in Eloquent Areas of Brain -- Management of Primary Central Nervous System Lymphomas -- Surgical Management of Brain Stem Tumors in Adults -- Cerebellar Tumors in Adults -- Surgical Management of Cerebral Metastases -- Multimodal Assessment of Pituitary and Parasellar Lesions -- Medical Management of Hormone-Secreting Pituitary Tumors -- Growth Hormone-Secreting Tumors -- Prolactinomas -- Cushing's Disease -- Endocrinologically Silent Pituitary Tumors -- Endoscopic Endonasal Pituitary and Skull Base Surgery -- Transcranial Surgery for Pituitary Macroadenomas -- Craniopharyngiomas -- Endoscopic Endonasal Approach for Craniopharyngiomas -- Arachnoid, Suprasellar, and Rathke's Cleft Cysts -- Surgical Approaches to Lateral and Third Ventricular Tumors -- Transcallosal Surgery of Lesions Affecting the Third Ventricle: Basic Principles -- Endoscopic Approach to Intraventricular Brain Tumors -- Management of Pineal Region Tumors -- Management of Tumors of the Fourth Ventricle -- Surgical Management of Parasagittal and Convexity Meningiomas -- Surgical Approach to Falcine Meningiomas -- Surgical Management of Midline Anterior Skull Base Meningiomas -- Supraorbital Approach Variants for Intracranial Tumors -- Surgical Management of Sphenoid Wing Meningiomas -- Spheno-Orbital Meningioma -- Tumors Involving the Cavernous Sinus -- Surgery for Trigeminal Neurinomas -- Surgical Management of Petroclival Meningiomas -- Surgical Management of Lesions of the Clivus -- Surgical Management of Posterior Fossa Meningiomas -- Surgical Management of Tumors of the Foramen Magnum -- Surgical Management of Tumors of the Jugular Foramen -- Suboccipital Retrosigmoid Surgical Approach for Vestibular Schwannoma (Acoustic Neuroma) -- Translabyrinthine Approach to Vestibular Schwannomas -- Transtemporal Approaches to Posterior Cranial Fossa -- Surgical Management of Neurofibromatosis Types 1 and 2 -- Hearing Prosthetics: Surgical Techniques -- Multimodal Treatment of Orbital Tumors -- Surgical Approaches to the Orbit -- Anterior Midline Approaches to the Skull Base -- Orbitozygomatic Infratemporal Approach to Parasellar Meningiomas -- Methods for Cerebrospinal Fluid Diversion in Pediatric Hydrocephalus: From Shunt to Scope -- Posterior Fossa Tumors in the Pediatric Population: Multidisciplinary Management -- Supratentorial Tumors in the Pediatric Population: Multidisciplinary Management -- Mapping, Disconnection, and Resective Surgery in Pediatric Epilepsy -- Surgical Decision-Making and Treatment Options for Chiari Malformations in Children -- Fetal Surgery for Open Neural Tube Defects -- Surgical Management of Spinal Dysraphism -- Revascularization Techniques in Pediatric Cerebrovascular Disorders -- Management of Pediatric Severe Traumatic Brain Injury -- Contemporary Dorsal Rhizotomy Surgery for the Treatment of Spasticity in Childhood -- Instrumentation and Stabilization of the Pediatric Spine: Technical Nuances and Age-Specific Considerations -- Methods of Cranial Vault Reconstruction for Craniosynostosis -- Surgical Management of Extracranial Carotid Artery Disease -- Management of Dissections of the Carotid and Vertebral Arteries -- Management of Unruptured Intracranial Aneurysms -- Surgical Management of Intracerebral Hemorrhage -- Surgical Management of Cerebellar Stroke-Hemorrhage and Infarction -- Surgical Treatment of Moyamoya Disease in Adults -- Surgical Treatment of Paraclinoid Aneurysms -- Surgical Management of Posterior Communicating, Anterior Choroidal, Carotid Bifurcation Aneurysms -- Surgical Management of Anterior Communicating and Anterior Cerebral Artery Aneurysms -- Surgical Management of Aneurysms of the Middle Cerebral Artery -- Surgical Management of Terminal Basilar and Posterior Cerebral Artery Aneurysms -- Surgical Management of Midbasilar and Lower Basilar Aneurysms -- Surgical Management of Aneurysms of the Vertebral and Posterior Inferior Cerebellar Artery Complex -- Far Lateral Approach and Transcondylar and Supracondylar Extensions for Aneurysms of the Vertebrobasilar Junction -- Surgical Management of Cranial Dural Arteriovenous Fistulas -- Surgical Management of Cavernous Malformations of the Nervous System -- Surgical Management of Infratentorial Arteriovenous Malformations -- Surgical Management of Cerebral Arteriovenous Malformations -- Endovascular Management of Intracranial Aneurysms -- Endovascular Treatment of Stroke -- Endovascular Treatment of Cerebral Arteriovenous Malformations -- Endovascular Treatment of Intracranial Occlusive Disease -- Endovascular Treatment of Extracranial Occlusive Disease -- Embolization of Tumors: Brain, Head, Neck, and Spine -- Endovascular Management of Dural Arteriovenous Fistulas -- Endovascular Management of Spinal Vascular Malformations -- Endovascular Treatment of Head and Neck Bleeding -- Imaging Evaluation and Endovascular Treatment of Vasospasm -- Surgical Management of Hydrocephalus in the Adult -- Adult Pseudotumor Cerebri Syndrome -- Endoscopic Third Ventriculostomy -- Management of Shunt Infections -- Interstitial and LINAC-Radiosurgery for Brain Metastases -- Stereotactic Radiosurgery for Trigeminal Neuralgia -- CyberKnife Radiosurgery for Spinal Neoplasms -- Stereotactic Radiosurgery for Pituitary Adenomas -- Radiation Therapy and Radiosurgery in the Management of Craniopharyngiomas -- Vestibular Schwannomas: The Role of Stereotactic Radiosurgery -- Stereotactic Radiosurgery Meningiomas -- Role of Gamma Knife Radiosurgery in the Management of Arteriovenous Malformations -- Radiation Therapy of Epilepsy -- Gamma Surgery for Functional Disorders -- V. 2: -- Presurgical Evaluation for Epilepsy Including Intracranial Electrodes -- Temporal Lobe Operations in Intractable Epilepsy -- Surgical Management of Extratemporal Lobe Epilepsy -- Multilobar Resection and Hemispherectomy in Epilepsy Surgery -- Corpus Callosotomy: Indications and Techniques -- Treatment of Intractable Epilepsy by Electrical Stimulation of the Vagus Nerve -- Deep Brain Stimulation in Movement Disorders: Parkinson's Disease, Essential Tremor, and Dystonia -- Cervical Dystonia and Spasmodic Torticollis: Indications and Techniques -- Novel Targets in Deep Brain Stimulation for Movement Disorders -- Molecular Therapies for Movement Disorders -- Cingulotomy for Intractable Psychiatric Illness -- Deep Brain Stimulation for Intractable Psychiatric Illness -- Brain-Computer Interfacing Prospects and Technical Aspects -- Thoracoscopic Sympathectomy for Hyperhidrosis -- Surgery for Intractable Spasticity -- Retrogasserian Glycerol Rhizolysis in Trigeminal Neuralgia -- Percutaneous Stereotactic Rhizotomy in the Treatment of Intractable Facial Pain -- Neurovascular Decompression in Cranial Nerves V, VII, IX, and X -- Deep Brain Stimulation for Pain -- Mesencephalic Tractotomy and Anterolateral Cordotomy for Intractable Pain -- Spinal Cord Stimulation for Chronic Pain -- Spinal Cord Stimulation and Intraspinal Infusions for Pain -- Dorsal Root Entry Zone Lesions -- Motor Cortex Stimulation for Intractable Facial Pain -- Perioperative Management of Severe Traumatic Brain Injury in Adults -- Surgical Management of Severe Closed Head Injury in Adults -- Management of Penetrating and Blast Injuries of the Nervous System -- Decompressive Craniectomy for Traumatic Brain Injury -- Management of Skull Base Trauma -- Surgical Management of Chronic Subdural Hematoma in Adults -- Management of Cerebrospinal Fluid Leaks -- Principles of Scalp Surgery and Surgical Management of Major Defects of Scalp -- Surgical Management of Major Skull Defects and Potential Complications -- Management of Traumatic Intracranial Aneurysms -- Management of Penetrating Brain Injury -- Management of Suppurative Intracranial Infections -- Management of Infections After Craniotomy -- Spinal Infections: Vertebral Osteomyelitis and Spinal Epidural Abscess -- Neurosurgical Management of HIV-Related Focal Brain Lesions -- Management of Neurocysticercosis -- Management of Tuberculous Infections of the Nervous System -- Fungal Infections of the Central Nervous System -- Management of Intracranial Aneurysms Caused by Infection -- Treatment Evolution in Management of Cervical Disc Disease -- Anterior Cervical Foraminotomy (Jho Procedure): Microscopic or Endoscopic -- Minimally Invasive Posterior Cervical Foraminotomy and Microdiscectomy -- Disc Replacement Technologies in the Cervical and Lumbar Spine -- Anterior Approaches for Multilevel Cervical Spondylosis -- Management of Cervical Spondylotic Myelopathy -- Cervical Laminoplasty: Indications and Techniques -- Circumferential Cervical Spinal Fusion -- Surgical Techniques in the Management of Thoracic Disc Herniations -- Video-Assisted Thoracoscopic Discectomy: Indications and Techniques -- Lumbar Microdiscectomy: Indications and Techniques -- Lumbar Microdiscectomy: Indications and Techniques -- Minimally Invasive Lumbar Microdiscectomy: Indications and Techniques -- Management of Far Lateral Lumbar Disc Herniations -- Lumbar Spinal Arthroplasty: Clinical Experiences of Motion Preservation -- Management of Degenerative Lumbar Stenosis and Spondylolisthesis -- Posterior Lumbar Fusion by Open Technique: Indications and Techniques -- Percutaneous Placement of Lumbar Pedicle Screws: Indications and Techniques -- Dynamic Stabilization of the Lumbar Spine: Indications and Techniques -- Posterior Lumbar Interbody Fusion -- Transforaminal Lumbar Interbody Fusion: Indications and Techniques -- Anterior Lumbar Interbody Fusion: Indications and Techniques -- Lateral Lumbar Interbody Fusion: Indications and Techniques -- Vertebroplasty and Kyphoplasty: Indications and Techniques -- Management of Injuries of the Cervical Spine and Spinal Cord -- Transoral Approaches to the Cervical Spine -- Atlantoaxial Instability and Stabilization -- Stabilization of the Subaxial Cervical Spine (C3-C7) -- Thoracolumbar Anterolateral and Posterior Stabilization -- Management of Sacral Fractures -- Management of Penetrating Injuries to the Spine -- Craniovertebral Abnormalities and Their Neurosurgical Management -- Management of Chiari Malformations and Syringomyelia -- Management of Occult Spinal Dysraphism in Adults -- Neurologic Problems of the Spine in Achondroplasia -- Management of Degenerative Scoliosis -- Surgical Management of Intramedullary Spinal Cord Tumors in Adults -- Intradural Extramedullary Tumors -- Management of Spinal Cord Tumors and Arteriovenous Malformations -- Management of Cauda Equina Tumors -- Management of Primary Malignant Tumors of the Osseous Spine -- Surgical Approaches to the Cervicothoracic Junction -- Surgery for Metastatic Spine Disease -- Surgical Resection of Sacral Tumors -- Surgical Management of Cerebrospinal Fluid Leakage after Spinal Surgery -- Peripheral Nerve Injury -- Imaging for Peripheral Nerve Disorders -- Management of Adult Brachial Plexus Injuries -- Nerve Transfers: Indications and Techniques -- Management of Median Nerve Compression -- Management of Ulnar Nerve Compression -- Management of Entrapment Neuropathies -- Management of Nerve Sheath Tumors Involving the Spine -- Peripheral Nerve Tumors of the Extremities -- Management of Cranial Nerve Injuries -- Management of Thoracic Outlet Syndrome -- Nerve-Grafting Procedures for Birth-Related Peripheral Nerve Injuries.
  • Digital
    edited by Stan Kutcher, Yifeng Wei, Mark D. Weist.
    Digital : Cambridge2015
    "This book related to fundamental recognitions that 1) children, adolescents, and families usually make no or very poor connections to specialty mental health (see Atkins et al. 1998; Catron, Harris, & Weiss, 1999), 2) schools are where children and youth are, and 3) many advantages accrue when education, mental health, and other youth-serving systems join together to better meet the mental health needs of students, in ways that reflect reducing and removing barriers to learning (Andis et al., 2002; Weist, 1997). National and global networks are increasingly recognizing the centrality of the SMH agenda as reflected in increasing funding, growing training opportunities, key policy initiatives, and an advancing research base that involves localities, states, regions and countries pursuing common themes"--Provided by publisher.
  • Digital
    Digital2017-
    Includes information about medical faculty organization: the professoriate, clinician educators, academic staff, adjunct clinical faculty, instructors, visiting scholars, acting faculty, visiting faculty, visiting instructors, consulting faculty, and more.
  • Digital
    Thomas W. Miller, editor.
    Digital : Springer2008
    School-related violence and prevention : editorial introduction / Thomas W. Miller -- Theory, assessment, and forms of school violence: School-related violence : definition, scope, and prevention goals / Thomas W. Miller and Robert F. Kraus. The neurobiology of violence and victimization / William P. French. Threat assessment in school violence / Connie Callahan. Social information processing and aggression in understanding school violence : an application of Crick and Dodge's model / Amy Nigoff. The roles of morality development and personal power in mass school shootings / Ken Kyle and Stephen Thompson. Multiple contextual levels of risk for peer victimization : a review with implications for prevention and intervention efforts / Noel A. Card, Jenny Isaacs, and Ernest V. E. Hodges. Assessment of childhood sexual abuse : clinical measures, evaluation, and treatment / Mark V. Sapp. Impact of trauma in school violence on the victim and the perpetrator : a mental health perspective / Lane J. Veltkamp and Amy Lawson. Boundary violations : harassment, exploitation, and abuse / Thomas W. Miller and Lane J. Veltkamp. Cliques and cults as a contributor to violence in the school environment / Thomas W. Miller, Thomas F. Holcomb, and Robert F. Kraus -- Teatment and prevention of violence in the schools: Violence in our schools / Matt Thompson, Bobbie Burcham, and Kathy McLaughlin. The role of teachers in school violence and bullying prevention / Jina S. Yoon and Elizabeth Barton. Developmental issues in the prevention of aggression and violence in school / Paul Boxer, Andrew Terranova, Sarah Savoy, and Sara E. Goldstein. Bullies and victims at school : perspectives and strategies for primary prevention / Christian Berger, Ramin Karimpour, and Philip C. Rodkin. The psychiatrist's role after a school shooting: the emergency room and beyond / Elissa P. Benedek and Praveen Kambam. Current perspectives on linking school bullying research to effective prevention strategies / Dorothy L. Espelage and Susan M. Swearer. School shootings in middle school, high school, and college : clinical management and school interventions for high-risk students / Thomas W. Miller, William Weitzel, and Janet Lane. Character education as a prevention strategy for school-related violence / Thomas W. Miller, Robert F. Kraus, and Lane J. Veltkamp. The bully free program : a profile for prevention in the school setting / Allan Beane, Thomas W. Miller, and Rick Spurling. A series of culturally relevant models to prevent school-age youth violence : a 4-year (2001-2005) family and community violence prevention study / Laxley W. Rodney, Rameshwar P. Srivastava, and Dana L. Johnson. Prevention of school violence : directions, summary, and conclusions / J. Robert McLaughlin and Thomas W. Miller.
  • Digital
    Coffman, Thomas M.; Falk, Ronald J.; Molitoris, Bruce A.; Neilson, Eric G.; Schrier, Robert W.
    Digital : Ovid2013
    "The recent advances in many aspects of kidney diseases have mandated a new edition of Schrier's Diseases of the Kidney. As in previous editions, a group of international experts was assembled to present this information in a comprehensive, authoritative, concise, and readily accessible fashion. The chapters have been extensively revised and updated"--Provided by publisher.
  • Digital
    Julie Rebecca Perlin.
    Digital2012
    The nervous system connects cells throughout the body to coordinate actions and transmit signals. Critical to the nervous system are the neurons that extend axons to their targets and the glial cells that interact with these axons. Oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system wrap axons to make the myelin sheath. Myelin is critical for enhancing the speed of action potentials as well as providing support to axons. Myelin was a critical adaptation that has allowed vertebrates to increase in size, precision of movement, and complexity. Insults to myelin cause devastating diseases, and a better understanding of the normal development of myelinating glia is necessary for improving treatment of human neuropathies. In this dissertation I investigate both well-known and novel signaling pathways and their roles in Schwann cell migration and myelination in zebrafish peripheral nerves. Before making myelin, Schwann cells must migrate along and cover the surface of a bundle of axons. Here, I demonstrate that Neuregulin 1 type III (Nrg 1 type III) is required in neurons to signal through ErbB receptors in Schwann cells for Schwann cell migration along the posterior lateral line nerve, a mechanosensory nerve. Further, ectopic expression of this signal in all neurons is sufficient to attract peripheral Schwann cells into the spinal cord. There appears to be distinct regulation of Schwann cell migration in different nerves of the peripheral nervous system, as migration of Schwann cells in motor nerves requires ErbB receptors but not the Nrg 1 type III ligand. Nrg1 type III does, however, control myelination in both sensory and motor nerves. Schwann cell migration is not only important to properly localize Schwann cells, but also to localize the lateral line nerve itself, which begins in the epidermis but then transitions across a basement membrane to the subepidermal space. As they migrate, Schwann cells degrade the basement membrane beneath the skin, which allows the nerve to transition out of the epidermis, and then rebuild the basement membrane after the nerve has been repositioned and protected from the disorganization that otherwise would take place if it remained in the epidermis. Finally, through analysis of a mutation that was found in a forward genetic screen for genes essential in myelination, I also identify a novel regulator of Schwann cell myelination. Together this work elucidates new roles of known genes in Schwann cell and nerve development and also identifies a novel gene required for peripheral myelination.
  • Print
    editor, Joseph J. Zorc ; associate editors, Elizabeth R. Alpern ... [et al.].
    Print2009
    Status: Not Checked OutLane Catalog Record
  • Digital
    editor-in-chief, F. Charles Brunicardi ; associate editors, Dana K. Andersen ... [et al.].
    Digital : AccessMedicine2010
    Digital : AccessSurgery2010
    Accreditation council for graduate medical education core competencies -- Systemic response injury and metabolic support -- Fluid and electrolyte management of the surgical patient -- Hemostasis, surgical bleeding, and transfusion -- Shock -- Surgical infections -- Trauma -- Burns -- Wound healing -- Oncology -- Transplantation -- Patient safety -- Physiologic monitoring of the surgical patient -- Minimally invasive surgery, robotics, and natural orifice transluminal endoscopic surgery -- Molecular and genomic surgery -- The skin and subcutaneous tissue -- The breast -- Disorders of the head and neck -- Chest wall, lung, mediastinum, and pleura -- Congenital heart disease -- Acquired heart disease -- Thoracic aneurysms and aortic dissection -- Arterial disease -- Venous and lymphatic disease -- Esophagus and diaphragmatic hernia -- Stomach -- The surgical management of obesity -- Small intestine -- Colon, rectum, and anus -- The appendix -- Liver -- Gallbladder and the extrahepatic biliary system -- Pancreas -- Spleen -- Abdominal wall, omentum, mesentery, and retroperitoneum -- Soft tissue sarcomas -- Inguinal hernias -- Thyroid, parathyroid, and adrenal -- Pediatric surgery -- Urology -- Gynecology -- Neurosurgery -- Orthopedic surgery -- Surgery of the hand and wrist -- Plastic and reconstructive surgery -- Surgical considerations in the elderly -- Anesthesia of the surgical patient -- Ethics, palliative care, and care at the end of life.
  • Digital
    editor-in-chief, F. Charles Brunicardi ; associate editors, Dana K. Andersen, Timothy R. Billiar, David L. Dunn, John G. Hunter, Jeffrey B. Matthews, Raphael E. Pollock.
    Digital : AccessSurgery2014
  • Print
    editor-in-chief, F. Charles Brunicardi ; associate editors, Mary L. Brandt ... [et al.].
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    Stanley N. Cohen ; with an introduction by Stanley Falkow ; interviews conducted by Sally Smith Hughes in 1995.
    Digital2009
    Print2009
  • Digital
    Edward D. Zanders.
    Digital : Springer2011
    Introduction -- pt. I. Background to drug discovery and development -- pt. II. The drug development pipeline: discovery to testing in humans -- pt. III. The drug development pipeline: clinical trials to marketing authorization -- pt. IV. The global pharmaceuticals business -- pt. V. Professional interactions with drug discovery industry.
  • Print
    by Joseph Needham.
    Status: Not Checked OutLane Catalog Record
  • Digital
    Derek S. Wheeler, Hector R. Wong, and Thomas P. Shanley, (eds.).
    Digital : Springer2009
    The care of critically ill and injured children needs to be safe, evidence-based, equitable, efficient, timely, and family-centered. "Science and Practice of Pediatric Critical Care Medicine" discusses these changes in the specialty in greater scope and detail, offering the reader fresh insight into not only where we came from, but also where we are going as a specialty. Thus, this book is designed for all involved in the management of the pediatric critically ill patient, from physicians, residents and fellows in critical care, pulmonology, cardiology and pediatricians to specialist.
  • Digital
    editor, Marco Romanelli ; coeditors, Michael Clark ... [et al.].
    Digital : Springer2006
  • Digital
    Peter J. Snyder, Linda C. Mayes, Dennis D. Spencer ; with invited essays.
    Digital : ScienceDirect2009
    Medicine, media, and the dramaturgy of biomedical research: historical perspectives / John H. Warner -- Delgado's brave bulls: the marketing of a seductive idea and a lesson for contemporary biomedical research / Peter J. Snyder -- Adrenal transplantation for Parkinson's disease / Dennis D. Spencer -- The use of SSRIs in the treatment of childhood depression: a scientific dialectic / Peter Fonagy -- Media coverage of stem cell research / David H. Smith, Aaron Klink, Julius Landwirth -- Medicine's obsession with disclosure of financial conflicts: fixing the wrong problem / Jerome P. Kassirer -- In support of industry-sponsored clinical research / Declan P. Doogan -- Prevailing truth: the interface between religion and science / Wesley Carr -- Science meets fundamentalist religion / Pat Shipman -- Uneasy alliance: the intersection of government science, politics and policymaking / Ruth J. Katz -- On the relationship between scientists and journalists: reflections by an ethicist / Robert J. Levine -- Don't shoot the messenger / Laura Spinney -- Future trends in medical research publishing / Harry W. McConnell, Ashley Pardy -- Conclusion: the ethics of scientific disclosure / Peter J. Snyder, Linda C. Mayes.
  • Print
    Gordon Binder, Philip Bashe
    Status: Not Checked OutLane Catalog Record
  • Digital
    Palmer, B. J.
    Digital : Google BooksFulltext (v.3 1911)
    Digital : Google BooksFulltext (v.5 1920)
    Digital : Google BooksFulltext (v.9 1920)
  • Digital
    edited by Stefan G. Hofmann, Gordon J.G. Asmundson.
    Digital : ScienceDirect2017
    The generic model of cognitive behavioral therapy / Scott H. Waltman and Leslie Sokol -- Treatment-relevant assessment in cognitive-behavioral therapy / Katerina Rnic and David J.A. Dozois -- Learning principles in CBT / Michelle L. Davis, Sara M. Witcraft, Scarlett O. Baird and Jasper A.J. Smits -- Cognitive processes in CBT / Eni S. Becker and Janna N. Vrijsen -- Emotion regulation in cognitive-behavioral therapy / Andre J. Plate and Amelia Aldao -- Combined treatment with CBT and psychopharmacology / Josie Lee, Bridget A. Hearon and Michael W. Otto -- Acceptance and commitment therapy and the cognitive behavioral tradition / Frederick Chin and Steven C. Hayes -- Mindfulness-based cognitive behavioral treatments / Lizabeth Roemer, Natalie Arbid, Jennifer H. Martinez and Susan M. Orsillo -- Global to local / Anushka Patel and Devon Hinton -- Cognitive-behavioral therapy in older adults / Elizabeth C. Conti, Cynthia Kraus-Schulman and Melinda A. Stanley -- Cognitive-behavioral therapy for children and adolescents / Danielle Cornacchio, Amanda L. Sanchez, Tommy Chou and Jonathan S. Comer -- Behavioral activation treatments for depression / Leanne Quigley and Keith S. Dobson -- Posttraumatic stress disorder / Richard A. Bryant -- Eating disorders / Zafra Cooper and Riccardo D. Grave -- Transdiagnostic treatment for anxiety disorders / Laren R. Conklin and Hannah Boettcher -- Cognitive behavioral therapy for sleep disorders / Caitlin E. Gasperetti, Michael R. Dolsen and Allison G. Harvey -- Cognitive behavioral therapy for somafom disorders and / Maria Kleinstäuber and Winfried Rief -- Dialectical behavior therapy / Anita Lungu and Marsha M. Linehan -- Cognitive bias modification / Jennie M. Kuckertz and Nader Amir -- Cognitive training in schizophrenia / Kristen M. Haut, Vijay A. Mittal, Stewart A. Shankman and Christine I. Hooker -- Internet-based cognitive behavior therapy / Gerhard Andersson, Per Carlbring and Heather D. Hadjustavropoulos -- Virtual reality and other realities / Cristina Botella, Rosa M. Baños, Azucena García-Palacios and Soledad Quero.
  • Digital
    edited by Erich Grotewold.
    Digital : Springer2006
  • Print
    Nathaniel Comfort.
    Print2012
    "Keeping his focus on America, Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed that the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and skeptically"-- Provided by publisher.
  • Digital
    Daniel Reisberg.
    Digital : OSO2014
    Machine generated contents note: -- Preface -- 1. Foundations -- 2. Perception -- 3. Memory -- 4. Witness IDs -- 5. ID Procedures -- 6. Voices and Conversation -- 7. Lies -- 8. Confessions -- 9. Jury Cognition -- 10. Kids -- 11. Kid Investigations -- Epilogue -- References.
  • Print
    John E. Brush, Jr., MD.
    Print2015
    Status: Not Checked OutLane Catalog Record
    Chapter 1. Uncertainty in clinical medicine -- Chapter 2. The logic of medicine -- Chapter 3. Probability: uncertainty quantified -- Chapter 4. Decision making: making choices -- Chapter 5. Solving unstructured problems -- Chapter 6. Therapeutic decision making -- Chapter 7. Evidence-based medicine -- Chapter 8. Improving the quality of care -- Chapter 9. Common fallacies -- Chapter 10. Putting this book into practice -- Appendix 1. More on probability curves -- Appendix 2. More on likelihood ratios -- Appendix 3. The minimum Bayes factor and likelihood ratios.
  • Digital
    Ed Diener, ed.
    Digital : Springer2009
    Introduction : the science of well-being : reviews and theoretical articles by Ed Diener / Ed Diener -- Subjective well-being / Ed Diener -- In pursuit of happiness : empirical answers to philosophical questions / Pelin Kesebir and Ed Diener -- Personality and subjective well-being / Richard E. Lucas and Ed Diener -- Beyond the hedonic treadmill : revising the adaptation theory of well-being / Ed DIener, RIchard E. Lucas and Christie Napa Scollon -- Will money increase subjective well-being? : a literature review and guide to needed research / Ed Diener and Robert Biswas-Diener -- The well-being of nations : linking together trust, cooperation, and democracy / William Tov and Ed Diener -- The optimum level of well-being : can people be too happy? / Shigehiro Oishi, Ed Diener, and Richard E. Lucas -- Beyond money : toward an economy of well-being / Ed Diener and Martin E.P. Seligman -- Conclusion : the well-being science needed now / Ed Diener.
  • Digital
    Bertram Ludäscher, Nikos Mamoulis (eds.).
    Digital : Springer2008
  • Digital
    John Blackwell, Jan Martin.
    Digital : Springer2011
    The book does not focus primarily on grammar, but includes sections on important facets, such as 'voices' and tenses. It also addresses problems associated with writing other texts (reports, reviews, emails, social/professional networking communications etc.). Composed (with inputs from numerous senior scientists) by authors who have written, revised or edited more than 4,000 papers, A Scientific Approach to Scientific Writing will be essential reading for non-native English-speaking students and researchers of all disciplines, and a valuable resource for those with English as a first language."--pub. desc.
  • Digital
    volume editors, Hideki Kawanishi, Yoshiaki Takemoto.
    Digital : Karger2017
  • Digital
    editors, Colin R. Martin, Victor R. Preedy.
    Digital : CRCnetBASE2012
    "In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. The volume on Arthritis covers, rheumatoid arthritis, cytokines, leukocyte immunoglobulin-like receptors, alleles, cardiovascular risk, disease outcomes, treatment protocols, and drugs for arthritis. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.
  • Digital
    editors, Colin R. Martin, Victor R. Preedy.
    Digital : CRCnetBASE2012
    "In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. This volume on Asthma covers, inter alia, asthma care in primary care centers, rhinosinusitis and asthma, asthma and psychological distress, inhalation techniques for different inhalers, emergency treatment for acute asthma, therapy for elderly patients, treatment for pediatric asthma, nursing care at home and so on. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.
  • Digital
    editors, Colin R. Martin, Victor R. Preedy.
    Digital : CRCnetBASE2012
    HIV/AIDS : an overview / Francis Agyemang-Yeboah and Bernard C. Nkum -- Can teens teach other teens HIV prevention? : implications for AIDS and pregnancy / Ganga Mahat and Maryann Scoloveno -- Knowledge of antenatal attendees about HIV/AIDS in pregnancy / Anietie Effiong Moses, Emem Abasi Bassey, and Godwin Etim Asuquo -- Midwives and occupational exposures to HIV / Maria Ganczak -- Pregnancy and delivery in HIV positive women : antenatal care and outcome / Karoline Aebi-Popp, Christoph Rudin, and Luigia Elzi -- Management of HIV/AIDS stigma : nursing perspectives / Susan W. Gaskins -- Prenatal assistance to pregnant women with HIV/AIDS / Prescilla Chow ... [et al.] -- Antenatal screening and HIV-pregnancy : strategies for treatment / Ali A. Al-Jabri ... [et al.] -- Low lymphocyte count in HIV-pregnancy and strategies for treatment / Alashle Abimiku and Evaezi Okpokoro -- Antiretroviral regimens recommended for prevention of mother-to-child transmission of HIV / Christiana Smith and Adriana Weinberg -- Pregnancy-related adverse effects of antiretroviral therapy / Elie Azria, Sophie Matheron, and Dominique Luton.
  • Digital
    editors, Colin R. Martin, Victor R. Preedy.
    Digital : CRCnetBASE2012
    Epidemiology of angina / John F. Beltrame -- Chest pain : cardiac and non-cardiac causes / Geraldine Lee -- Coronary plaque rupture in patients with acute coronary syndrome / Toshio Imanishi -- The use and application of angina questionnaires / Norul Badriah Hassan and Muhammad Termizi Hassan -- American College of Cardiology/American Heart Association guidelines for ST-elevation myocardial infarction : overview of guidelines for care before, during, and after STEMI / Rohit S. Loomba and Rohit R. Arora -- Non-invasive coronary angiography with cardiac CT in patients with angina pectoris / Christof Burgstahler, Harald Brodoefel, and Stephen Schroeder -- Drugs used in angina : an overview / Mario Marzilli and Alda Huqi -- Current clinical application of direct thrombin inhibitors in angina pectoris / Bernardo Cortese and Marco Centola -- Anti-anginal drugs in focus : trimetazidine / Mario Marzilli and Alda Huqi -- Enhanced external counterpulsation therapy in coronary artery disease management / Ozlem Soran and Debra L. Braverman.
  • Digital
    Len Wisneski, MD, FACP.
    Digital : TandFonline2017
    A review of classic physiological systems -- Systems integration : psychoneuroimmunology -- The stress system -- The relaxation system : theoretical construct -- The relaxation system : therapeutic modalities -- Energy medicine : cutting-edge modalities -- Energy medicine : focus on non-thermal electromagnetic therapies -- Energy medicine : focus on lasers -- The four pillars and two guideposts for the healing professions -- The pineal gland : energy transducer -- Soul medicine : crossing the boundary -- Human epigenetics in health and disease -- History and philosophy of naturopathic medicine -- Wellbeing -- Assessing the toxic load and detoxification strategies -- Precision nutrition -- The landscape of integrative medicine in America with a shift to prevention and health promotion -- Whole person caring -- Energy medicine : focus on lasers.
  • Print
    Javier Arias-Stella.
    Print2009
    Status: Not Checked OutLane Catalog Record
    Describes the path that led to the discovery of the Arias-Stella reaction. Uses fictional names for the local protagonists, e.g., Pedro Asari Saltel for Javier Arias-Stella.
  • Digital
    Robert A. Day and Nancy Sakaduski.
    Digital : ProQuest Ebook Central2011Limited to 1 simultaneous users
    Principles of scientific writing -- Kinds of writing -- Writing style -- The english language -- Grammar -- Words -- Name words (nouns and pronouns) -- Action words (verbs) -- Descriptive words (adjectives, adverbs, and articles) -- Function words (conjunctions, prepositions, and interjections) -- Prefixes and suffixes -- Redundancies and jargon -- Abbreviations, acronyms, and initialisms -- Phrases -- Clauses -- Sentences -- Paragraphs -- Voice, person, and tense -- Punctuation -- Writing for electronic media -- Appendix 1 : Principles of punctuation presented plainly -- Appendix 2 : Problem words and expressions -- Appendix 3 : Words and expressions to avoid.
  • Digital
    Elbert W. Russell.
    Digital : ScienceDirect2012
    Scientific neurological basis for assessment -- Introductory scientific history to neuropsychological assessment -- Nature of science -- Theoretical foundation of neurological assessment -- Neuropsychological basis of assessment -- Brain-function analysis -- Formal analytic methodology -- Neuropsychological battery patterns -- Justification of formal procedures -- Fundamental psychometric status of neuropsychological batteries -- Justification of neuropsychological batteries -- Accuracy of formal neuropsychological methods -- Application to forensics -- Admissibility of neuropsychological expert testimony under the Daubert and Frye evidentiary standards -- Usefulness of a validated neuropsychological test battery is scientifically supporting and communicating forensic evaluation results -- Formal neuropsychological methods -- In defense of the Halstead-Reitan Battery: a critique of Lezak's review -- In defense of the Halstead-Reitan Battery: revisited -- Norming subjects for the Halstead-Reitan Battery -- Major Halstead-Reitan Battern norm sets.
  • Digital
    report of the AAMC-HHMI Committee.
    Digital : AAMC2009
    Presents a new framework for preparing students with the scientific know-how optimal for studying medicine and becoming physicians.
  • Print
    edited by David L. Williams, Ronald F. Nunn, and Vincent Marks.
    Print1978-
    Status: Not Checked OutLane Catalog Record
    v. 1, Analytical aspects.
  • Print
    edited by David Innes Williams and Geoffrey D. Chisholm.
    Print1976-
    Status: Not Checked OutLane Catalog Record
    v.1 - Renal disorders infections and calculi. v.2 - Urogenital tract, oncology and the urological armamentarium.
  • Digital
    Jerry Sedgewick.
    Digital : ProQuest Safari2008
    Print2008
  • Print
    edited with a foreword by Barbara Newborg.
    Status: Not Checked OutLane Catalog Record
    v. 1. Studies in cellular physiology -- v. 2. Radical dietary treatment of vasular and metabolic disorders.
  • Digital
    Finlay MacRitchie.
    Digital : CRCnetBASE2011
    1. Introduction -- 2. Scientific training and personal development -- 3. The scientific method -- 4. Attributes required by research scientists -- 5. The impact of managerialism -- 6. Leadership in science -- 7. Insights from notable scientists -- 8. Future challenges for scientific research.
  • Digital
    edited by Robert J. Sternberg, Susan T. Fiske, Donald J. Foss.
    Digital : Cambridge2016
    Part I. Introduction -- Part II. Biological bases of psychology: genes, brain, and beyond -- Part III. Cognition: getting information from the world and dealing with it -- Part IV. Development: how we change over time -- Part V. Motivation and emotion: how we feel and what we do -- Part VI. Social and personality processes: who we are and how we interact -- Part VII. Clinical and health psychology: making lives better -- Part VIII. Conclusion.
  • Digital
    Maite Sainz de la Maza, Joseph Tauber, C. Stephen Foster.
    Digital : Springer2012
    Structural Considerations of the Sclera -- Immunologic Considerations of the Sclera -- Diagnostic Approach of Episcleritis and Scleritis -- Clinical Considerations of Episcleritis and Scleritis -- Pathology in Scleritis -- Noninfectious Scleritis -- Infectious Scleritis -- Noninflammatory Diseases of the Sclera -- Treatment of Episcleritis and Scleritis.
  • Digital
    John Varga, Christopher P. Denton, Fredrick M. Wigley, editors.
    Digital : Springer2012
    pt. 1. Introduction -- pt. 2. Epidemiology, genetics and classification -- pt. 3. Scleroderma in children -- pt. 4. Other fibrosing skin conditions -- pt. 5. Pathogenetic basis -- pt. 6. Cardiovascular manifestations and management -- pt. 7. Pulmonary manifestations and management -- pt. 8. Gastrointestinal manifestations and management -- pt. 9. Skin, musculoskeletal and other complications -- pt. 10. Disease-modifying strategies -- pt. 11. Outcome assessment.
  • Print
    Paulo Pacheco da Fontoura.
    Print2008
    Status: Not Checked OutLane Catalog Record
    I. Prefácio, por António Coutinho -- II. Notas para a História da Esclerose Múltipla, por Paulo Pacheco da Fontoura -- III. A Sclerose em Placas Disseminadas, por Vicente Ferreira de Moura -- IV. Notas Finais e Agradecimentos.
  • Digital
    Goldman, Mitchel P.; Guex, Jean-Jérôme; Weiss, Robert A.
    Digital : ScienceDirect2011
    Digital : ClinicalKey2011
  • Digital
    edited by Michael Gleeson.
    Digital : CRCnetBASE2008
    Volume 1: Cell biology -- Wound healing -- Immunology -- Microbiology -- Haematology -- Endocrinology -- Pharmacotherapeutics -- Perioperative management -- Safe and effective practice -- Interpreation and management of data -- Recent advances in technology -- Paediatric otorhinolaryngology -- Volume 2: The Nose and paranasal sinuses -- The neck -- The upper digestive tract -- The upper airway -- Head and neck tumours -- Volume 3: Plastic surgery of the head and neck -- The ear, hearing and balance -- Skull base.
  • Digital
    edited by Megan J. Coyer and David E. Shuttleton.
    Digital2014
    Print2014
    1.Introduction: Scottish medicine and literary culture, 1726-1832 / Megan J. Coyer and David E. Shuttleton -- 2. 'Nothing is so soon forgot as pain': reading agony in Adam Smith's The theory of moral sentiments / Craig Franson --3. The origins of a modern medical ethics in enlightenment Scotland: Cheyne, Gregory and Cullen as practitioners of sensibility / Wayne Wild -- 4. The demise of the preformed embryo: Edinburgh, Leiden, and the physician-poet Mark Akenside's contribution to re-establishing epigenetic embryology / Robin Dix -- 5. Benjamin Rush, Edinburgh medicine and the rise of physician autobiography / Catherine Jones -- 6. The construction of Robert Fergusson's illness and death / Rhona Brown -- 7. 'Groaning under the miseries of a diseased nervous system': Robert Burns and melancholy / Allan Beveridge -- 8. Phrenological controversy and the medical imagination: 'A modern pythagorean' in Blackwood's Edinburgh Magazine / Megan J. Coyer -- 9. Blood and the revenant in Walter Scott's The Fair Maid of Perth / Katherine Inglis -- 10. Magic, mind control, and the body electric: "Materia Medica" in Sir Walter Scott's library at Abbotsford / Lindsay Levy -- 11. An Account of ... William Cullen: John Thomson and the making of a medical biography / David E. Shuttleton -- 12. Transatlantic irritability: Brunonian sociology, America and mass culture in the nineteenth century / Gavin Budge -- Index.
  • Digital
    edited by M.F. Reiser ... [et al.].
    Digital : Springer2007
  • Print
    Print2010
    Status: Not Checked OutLane Catalog Record
  • Digital
    Cathy E. Lloyd, Frans Pouwer, Norbert Hermanns, editors.
    Digital : Springer2013
    Current epidemiological evidence suggests that at least one third of people with diabetes suffer from clinically relevant depressive disorders which often go unrecognized and untreated. Research also shows that people with depressive disorders have an increased risk of developing Type 2 diabetes. Furthermore, the prognosis is poorer for either disease when they are co-morbid than when they occur separately. Co-morbid depression and diabetes has a huge impact on quality of life and diabetes management, and is an important public health problem. While there are many screening instruments available to identify individuals who may have depression, selecting the most appropriate tool for use in a busy diabetes clinic or primary care setting may not be straightforward. Screening for Depression and Other Psychological Problems in Diabetes: A Practical Guide provides an up-to-date overview of available instruments for screening for depression in diabetes. The book reviews the most commonly used screening tools and considers their utility in a range of settings and countries. Guidance on the practical use of each tool is also provided. Other psychological problems found to be common in people with diabetes as well as diabetes-specific emotional difficulties are also considered. This book will appeal to a range of health care practitioners caring for people with diabetes, including diabetologists, general practitioners, practice nurses and diabetes specialist nurses. The issues considered here are applicable to all diabetes populations across the world and thus this book will appeal to a broad international readership as well as to researchers in the field of diabetes and mental health.
  • Digital
    Digital : OWH2013-
  • Digital
    E. Scott Sills, editor.
    Digital : Springer2015
    The Development of PGD -- Elements of Informed Consent for Preimplantation Genetic Diagnosis -- Follicular Recruitment & Oocyte Recovery in Assisted Reproduction -- Biomarker-based Flow-Cytometric Semen Analysis for Male Infertility Diagnostics and Clinical Decision Making in ART -- Comparison of Methods for Assessment of Sperm DNA Damage (Fragmentation) and Implications for the Assisted Reproductive Technologies -- Tweaking ICSI for a PGD program -- Comprehensive Chromosomal Screening from Polar Body Biopsy to Blastocyst Trophectoderm Sampling: Evidence and Considerations -- Polar Body Diagnosis -- An Alternative and Addition to Preimplantation Diagnosis -- Efficiency of Polar Body Biopsy for Aneuploidy Screening by DNA Microarray for Single Embryo Transfer -- Prediction of Embryo Viability by Morphokinetic Evaluation to Facilitate Single Transfer -- Comparison of PCR Techniques for Embryo Screening and Single Embryo Transfer -- Array CGH and Partial Genome Sequencing for Rapidly Karyotyping IVF Blastocysts Before Transfer -- Single Embryo Transfers Enabled by aCGH -- Current and Future Methodologies -- SNP array, qPCR, and next-generation sequencing based comprehensive chromosome screening -- Expanding PGD Applications to Non-traditional Genetic and Non-Genetic Conditions -- Should molecular cytogenetic techniques be applied to facilitate single embryo transfer in egg donation cases? Assessment of frequency and distribution of embryo aneuploidy after anonymous donor oocyte IVF -- Selecting the Single Embryo for Transfer in Mitochondrial Disorders -- Single Embryo Transfer: The Significance of the Embryo Transfer Technique -- The Vitrification Component: An Integral Part of a Successful eSET Program -- A Review of Luteal Support Protocols for Single Embryo Transfers -- Fresh and Frozen -- Cost effectiveness of single embryo transfers relative to higher embryo transfer policies in clinical practice: A population based analysis -- The Quebec experience -- One plus one equals two at once: Presenting cumulative pregnancy rates as the ideal outcome in elective SET programs -- Single Embryo Transfer in a State-Sponsored IVF Context: Current Experience from Israel -- Single Embryo Transfer: the Quebec Experience -- Regulatory Aspects of Embryo Testing: An American View -- Regulatory Challenges in Assisted Reproduction: A European Perspective -- Preimplantation Genetic Screening: Ethics & Policy -- Crossing Rubicons: Assisted Reproductive Therapies and Remaining Human.
  • Digital
    Michele Bertolotto, Carlo Trombetta, editors ; foreword by M.F. Reiser.
    Digital : Springer2012
  • Digital
    Richard S. Koplin, Elaine I. Wu, David C. Ritterband, John A. Seedor..
    Digital : Springer2013
    Introduction -- The Evolution of Eye Surgery -- The Advent of Ambulatory Eye Surgery -- Anatomical Considerations -- Infection Control -- How the Patient Gets from the Front Door of the ASC to Your OR Suite -- Decorum in the OR -- Setting Up in the OR -- Contemplating Cataract Surgery -- Cataract Surgery -- Complications Encountered, Instruments at the Ready: Here Is a List of "What Ifs" and "What to Do's" -- The Surgical Tray for Cataract Surgery -- Surgeon-Specific Instruments -- Ocular Biometry -- Self-Assessment Test Cataract Surgery -- Surgical Checklist -- Corneal Surgery -- Corneal Transplantation: Penetrating Keratoplasty -- Corneal Transplantation: Keratoprosthesis -- Corneal Transplantation: Endothelial Keratoplasty -- Pterygium Surgery -- Band Keratopathy Removal -- Complications Encountered, Instruments at the Ready: Here Is a List of "What Ifs" and "What to Do's" -- The Surgical Tray for Penetrating Keratoplasty -- The Surgical Tray for Endothelial Keratoplasty -- Self-Assessment Test Corneal Surgery -- Resource Materials -- Medications List.
  • Print
    guest editors : Daryl J. Kelly, Paul A. Fuerst, Wei-Mei Ching, Allen L. Richards.
    Print2009
  • Print
    Printv. 1-4(Most recent update 1987)
    Status: Not Checked OutLane Catalog Record
  • Digital
    David Stuart Lawrie.
    Digital2013
    During my graduate career, my research has focused on studying signals of purifying selection, using the tools of population genomics and molecular evolution to elucidate the underlying function of sites across the genome. In this thesis, I first focus on the theoretical implications of the interplay between weak constraint and mutational biases for divergence data between species. By explicitly incorporating the selective fitness of nucleotides into DNA substitution models, weak selection and mutational biases under this model can together have unexpected effects on the pattern of DNA sequence evolution over a phylogeny. In the next chapter, I investigate the selective forces acting on the synonymous sites of D. melanogaster, taking advantage of the high quality, deep population sequencing data available for that species. Within-species polymorphism data can allow for the detection of strong purifying selection using a combination of SNP density and allele frequency. Synonymous sites are generally assumed to be subject to weak selective constraint. However, contrary to this expectation, I demonstrate in Chapter 2 that a substantial proportion of synonymous sites in D. melanogaster are evolving under very strong selective constraint while few, if any are evolving under weak or moderate constraint. I conclude by examining the power and properties of using divergence and polymorphism to search for functional elements in a genome. There is a large potential gain in power from having deep samples of population variation in multiple related species, which, combined with divergence data, should allow for the estimation of selection coefficients on relatively few sites. Comparative population genomics, the analysis of large-scale population data within and between species, represents a powerful extension to current approaches using the evolutionary signatures of purifying selection to detect functional elements and ascertain their functional importance.
  • Digital
    Alex Pollen.
    Digital2012
    Understanding the genetic changes responsible for the evolution of human traits is a major goal of biology. One of the most distinctive human traits is the dramatic expansion of the forebrain that has occurred over the last six million years. Whole genome sequencing projects have identified millions of genomic differences that separate human and chimpanzee (Chimpanzee Sequencing and Analysis Consortium, 2005). However, connecting particular mutations to evolved human traits such as brain size remains challenging due to the vast number of mutations that have accumulated (Varki and Altheide 2005; Sikela, 2006). Nonetheless, recent evolutionary genetic studies are identifying the most prevalent types of genetic mechanisms contributing to evolved traits in natural populations, and studies of comparative and molecular development are providing an emerging picture for mechanisms by which human brain expansion could have occurred. By combining insights from evolutionary genetics and developmental neurobiology, this thesis aims to identify genomic differences that are particularly likely to have contributed to the evolutionary expansion of the human brain. First, this thesis provides evidence for the role of cis-regulatory mutations in the evolution of natural populations of stickleback fish. Next, this thesis describes a genomic screen we conducted identifying 510 deletions likely to remove cis-regulatory enhancers from the human genome. One of these deletions removes a developmental ventral forebrain enhancer near the tumor suppressor gene GADD45g, the loss of which may release a brake on cell division in particular regions of the brain during neurogenesis. A second deletion removes a developmental dorsolateral neocortex enhancer demonstrating the specificity by which evolution can affect particular regions of the brain. Finally, this thesis identifies a human enhancer near the gene BDNF that drives expression in the nail bed of the digit tips and the stomach, and could influence the distribution and function of mechanoreceptors.
  • Digital
    Caroline De Brún, Nicola Pearce-Smith.
    Digital : Wiley2013
    This is a user-friendly, hands-on guide to literature searching, which is an essential skill for all involved in health care research and development, researchers, and students from all disciplines.
  • Digital
    edited by Alberto Troccoli ... [et al.].
    Digital : Springer2008
  • Digital
    Madeleine C. Thomson, Ricardo Garcia-Herrera, Martin Beniston, editors.
    Digital : Springer2008
  • Digital
    Roland Rau.
    Digital : Springer2007
  • Digital
    Elizabeth Kavaler.
    Digital : Springer2006
  • Print
    Purkyně, Jan Evangelista.
    Status: Not Checked OutLane Catalog Record
    --sv. 2-5. [without special title].--sv. 6. Disertace Purkyňových žáků.--sv. 7. České práce fysiologické a morfologické.--sv. 8. Úvahy a pracé přírodovědné.--sv. 9. Věda, výchova, společnost, studie a úvahy.--sv. 10. Slavistické pracé.--sv. 11. Básně a překlady.--sv. 12. Fysiologie lidské mluvy a menší fysiologickě pracé.--sv. 13. Autobiografické stati. Bibliographia.
  • Digital
    Emilio Mordini, Dimitrios Tzovaras, editors.
    Digital : Springer2012
    Introduction / Emilio Mordini, Dimitrios Tzovaras, and Holly Ashton -- Epistemological foundation of biometrics / Giampaolo Ghilardi and Flavio Keller -- Biometric recognition : an overview / Anil K. Jain and Ajay Kumar -- Biometrics, privacy and agency / Annemarie Sprokkereef and Paul de Hert -- Gait and anthropomorphic profile biometrics : a step forward / Dimosthenis Ioannidis ... (et al.) -- Activity and event related biometrics / Anastasios Drosou and Dimitrios Tzovaras -- Electrophysiological biometrics : opportunities and risks / Alejandro Riera ... (et al.) -- Intelligent biometrics / Farzin Deravi -- Behavioral biometrics and human identity / Ben A.M. Schouten, Albert Ali Salah, and Rob van Kranenburg -- Behavioral biometrics : emerging trends and ethical risks / Günter Schumacher -- Facial recognition, facial expression and intention detection / Massimo Tistarelli, Susan E. Barrett, and Alice J. O'Toole -- The transparent body : medical information, physical privacy and respect for body integrity / Emilio Mordini and Holly Ashton -- Security in the danger zone : normative issues of next generation biometrics / Irma van der Ploeg -- The dark side of the moon : accountability, ethics and new biometrics / Juliet Lodge -- Conclusions / Emilio Mordini.
  • Digital
    edited by Francesco S. Pavone, Paul J. Campagnola.
    Digital : CRCnetBASE2014
    "Second harmonic generation serves as the basis for a microscope imaging contrast mechanism that visualizes cell and tissue structure and function. This book provides a complete overview of the principles underlying this technique and its current applications, including use in molecular sensing. Covering practical issues related to instrumentation, the text examines which kinds of external labels to use. It also gives detailed reviews of the use of second harmonic generation in biomedical research, from imaging of cancer and skin disorders to self-assembled gels, holographic SHG imaging, and tissue engineering applications"--Provided by publisher.
  • Print
    Arnold S. Relman.
    Print2007
    Status: Not Checked OutLane Catalog Record
    The commercialization of U.S. medicine -- The consequences of commercialized care -- The revolt of the payers -- "Consumer-driven" health care: the new new thing -- The reform we need -- Can we get there? do we want to? -- Lessons from Canada -- An open letter to my colleagues in the medical profession.
  • Digital
    Sidney Dekker.
    Digital : CRCnetBASE2013
    Victims -- Trauma -- Guilt -- Investigation -- Justice -- Forgiveness -- Support -- Resilience.
  • Digital
    MIT Critical Data.
    Digital : Springer2016
    Introduction to the Book -- Objectives of secondary analysis of EHR data -- Review of clinical database -- Challenges and opportunities -- Secondary Analysis of EHR Data Cookbook -- Overview -- Step 1: Formulate research question -- Step 2: Data extraction and preprocessing -- Step 3: Exploratory Analysis -- Step 4: Data analysis -- Step 5: Validation and sensitivity analysis -- Missing Data -- Noise vs. Outliers -- Case Studies -- Introduction -- Predictive Modeling: outcome prediction (discrete) -- Predictive Modeling: dose optimization (regression) -- Pharmacovigilance (classification) -- Comparative effectiveness: propensity score analysis -- Comparative effectiveness: instrumental variable analysis -- Decision and Cost Effectiveness Analysis: Hidden Markov models and Monte Carlo simulation -- Time series analysis: Gaussian processes (ICP modelling) -- Time series analysis: Bayesian inference (Motif discovery in numerical signals) -- Time Series analysis: Optimization techniques for hyperparameter selection -- Signal processing: analysis of waveform data -- Signal processing: False alarm reduction.
  • Digital
    Khalil Fattouch, Patrizio Lancellotti, Gianni D. Angelini, editors.
    Digital : Springer2015
    Open heart surgery has been in a continuous state of evolution since its earliest day. This book presents information on the management of secondary mitral valve regurgitation, one of most vexing problems to cardiologists, cardiac surgeons and patients. The treatment for primary mitral regurgitation is straightforward and has as its primary aim timely intervention to prevent left ventricular remodelling and left ventricular dysfunction. The management of secondary mitral regurgitation is more challenging as the mitral valve is not the primary cause of the disease. Furthermore, correcting mitral regurgitation without changing the left ventricular geometry is not guaranteed to be either beneficial or curative. Secondary Mitral Valve Regurgitation draws together contributions from a range of experienced cardiac surgeons, cardiologists, anesthetists and scientists to provide comprehensive and authoritative coverage on anatomy, hemodynamics, mechanism, echocardiographic assessment and treatment modalities. Many of the elusive details surrounding the best management of secondary mitral regurgitation are presented in a comprehensive manner so that this book will serve as an important primary source for readers wanting information on this important topic.
  • Digital
    Madeline Drexler.
    Digital : ProQuest Ebook Central2002
    Disease in disguise -- Winged victories -- Food fright -- Superbugs -- The once and future pandemic -- Infection unmasked -- Bioterror.
  • Print
    Londa Schiebinger.
    Print2017
    Status: Not Checked OutLane Catalog Record
    In the natural course of events, humans fall sick and die. The history of medicine bristles with attempts to find new and miraculous remedies, to work with and against nature to restore humans to health and well-being. In this book, Londa Schiebinger examines medicine and human experimentation in the Atlantic World, exploring the circulation of people, disease, plants, and knowledge between Europe, Africa, and the Americas. She traces the development of a colonial medical complex from the 1760s, when a robust experimental culture emerged in the British and French West Indies, to the early 1800s, when debates raged about banning the slave trade and, eventually, slavery itself. Massive mortality among enslaved Africans and European planters, soldiers, and sailors fueled the search for new healing techniques. Amerindian, African, and European knowledges competed to cure diseases emerging from the collision of peoples on newly established, often poorly supplied, plantations. But not all knowledge was equal. Highlighting the violence and fear endemic to colonial struggles, Schiebinger explores aspects of African medicine that were not put to the test, such as Obeah and vodou. This book analyzes how and why specific knowledges were blocked, discredited, or held secret.
  • Print
    Penelope A. Lewis.
    Print2013
    Neuroscientist Penny Lewis explores the latest research into the nighttime brain to understand the real benefits of sleep, showing how, while our body rests, the brain practices tasks it learned during the day, replays traumatic events to mollify them, and forges connections between distant concepts.
  • Digital
    L. Borbye.
    Digital : ScienceDirect2008
    Secrets to Success in Industry Careers introduces you to the differences between what is needed in school and what is needed in industry. It describes the entire process of obtaining a job including analysis of a job description, writing an application, preparation for an interview, and conduct during and after an interview. Most importantly, this book is the ideal industry-insider guide because it provides you with skills and understanding essential for success on the job. Fictional anecdotes make it easy to understand application of these skills, summarized at the end of each chapter and supported by self guided assessment questionnaires. This is the ideal guide on how to succeed for anyone seeking a job or already employed in both industry and academic environments. Self-assessment tools are included to help identify strengths and opportunities for growth Includes chapters on understanding business goals, leadership and teamwork, communication skills, marketing, discipline, flexibility, innovation, intellectual property, special technologies, quality, ethics, globalization, ambiguity, expectation and career management Author has developed highly successful industry-relevant training for students and new employees and has experience from both industry and academic environments Contains a compilation of essential technical and managerial skills necessary for success in industry, including chapters on expectation management and career management.
  • Print
    John S. Haller, Jr.
    Print2011
    1. Orthodoxy and American Practice -- 2. Old and New World Eclectics -- 3. Jeremiads and Apostates -- 4. Reform Literature -- 5. Reform Colleges -- 6. Reform Societies -- 7. Between the Abrahams -- Appendices -- A. Reform Medical Journals to 1909 -- B. Reform Medical Colleges to 1915 -- C. Reform Medical Societies to 1900.
  • Digital
    edited by E. Edmund Kim ... [et al.].
    Digital : Springer2007
  • Print
    [edited by] Georges Y. El-Khoury, William J. Montgomery, Ronald A. Bergman.
    Print2007
    Status: Not Checked OutLane Catalog Record
    CT of the abdomen / Kousei Ishigami -- MRI of the abdomen / Akihiro Nishie and Alan H. Stolpen -- CT of the male pelvis / Kousei Ishigami -- CT of the female pelvis / Kousei Ishigami -- MRI of the male pelvis / Akihiro Nishie and Alan H. Stolpen -- MRI of the female pelvis / Akihiro Nishie and Alan H. Stolpen. MR arthrography of the hip / Mark. J. Kransdorf -- MRI of the thigh / Mark J. Kransdorf -- MRI of the knee / Mark. J. Kransdorf -- MRI of the leg / Mark. J. Kransdorf -- MRI of the ankle / Mark. J. Kransdorf -- MRI of the foot / Mark. J. Kransdorf -- MRI of the thoracic spine / William J. Montgomery -- MRI of the lumbar spine / William J. Montgomery -- CT of the thorax / Brian F. Mullan -- MRI of the heart / Brian F. Mullan and Alan H. Stolpen -- MRI of the pectoral girdle and chest wall / Thomas P. Martin and Timothy Averion-Mahloch -- MRI of the shoulder / Thomas P. Martin and Timothy Averion-Mahloch -- MR arthrography of the shoulder / Thomas P. Martin and Timothy Averion-Mahloch -- MRI of the arm / Thomas P. Martin and Timothy Averion-Mahloch -- MRI of the elbow / Carol A. Boles -- MRI of the forearm / Carol A. Boles -- MRI of the wrist / Carol A. Boles -- MRI of the hand / Carol A. Boles -- MRI of the hip / Mark. J. Kransdorf --
  • Digital
    Mark W. Anderson, Michael G. Fox.
    Digital : ClinicalKey2017
    MRI of the pectoral girdle and chest wall -- MRI of the shoulder -- MR arthrography of the shoulder -- MRI of the arm -- MRI of the elbow -- MRI of the forearm -- MRI of the wrist -- MRI of the hand -- MRI of the hip -- MR arthrography of the hip -- MRI of the thigh -- MRI of the knee -- MRI of the leg -- MRI of the ankle -- MRI of the foot -- MRI of the thoracic spine -- MRI of the lumbar spine -- CT of the thorax -- MRI of the heart -- CT of the abdomen -- MRI of the abdomen -- CT of the male pelvis -- CTof the female pelvis -- MRI of the male pelvis -- MRI of the female pelvis.
  • Print
    Lorrie L. Kelley, Connie M. Petersen.
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    Stanley F. Malamed.
    Digital : ScienceDirect2018
    Digital : ClinicalKey2018
    Sedation in dentistry: a historic perspective -- Pain and anxiety in dentistry -- Introduction to sedation -- The spectrum of pain and anxiety control -- Physical and psychological evaluation -- Monitoring during sedation -- Nondrug techniques : iatrosedation and hypnosis -- Oral sedation -- Rectal sedation -- Sublingual, transdermal, and intranasal sedation -- Intramuscular sedation -- Inhalation sedation : historical perspective -- Inhalation sedation : rationale -- Pharmacology, anatomy, and physiology -- Inhalation sedation equipment -- Inhalation sedation : techniques of administration -- Inhalation sedation : complications -- Contemporary issues surrounding nitrous oxide -- Practical considerations -- Teaching inhalation sedation : history and present guidelines -- Intravenous sedation : historical perspective -- Intravenous moderate sedation : rationale -- Armamentarium -- Anatomy for venipuncture -- Venipuncture technique -- Pharmacology -- Intravenous moderate sedation : techniques of administration -- Intravenous sedation : complications -- Practical considerations -- Guidelines for teaching -- Fundamentals of general anesthesia -- Armamentarium, drugs, and techniques -- Preparation for emergencies -- Emergency drugs and equipment -- Management of emergencies -- The pediatric patient -- The geriatric patient -- The medically compromised patient -- The physically compromised patient -- Neurologic illnesses and other conditions -- Medicolegal considerations -- The controversial development of anesthesiology in dentistry.
  • Print
    Frankel, Lois P.
    Status: Not Checked OutLane Catalog Record
  • Digital
    Savvas Andronikou, editor.
    Digital : Springer2012
    This atlas demonstrates all components of the body through imaging, in much the same way that a geographical atlas demonstrates components of the world. Each body system and organ is imaged in every plane using all relevant modalities, allowing the reader to gain knowledge of density and signal intensity. Areas and methods not usually featured in imaging atlases are addressed, including the cranial nerve pathways, white matter tractography, and pediatric imaging. As the emphasis is very much on high-quality images with detailed labeling, there is no significant written component; however, 'pearl boxes' are scattered throughout the book to provide the reader with greater insight. This atlas will be an invaluable aid to students and clinicians with a radiological image in hand, as it will enable them to look up an exact replica and identify the anatomical components. The message to the reader is: Choose an organ, read the 'map,' and enjoy the journey.
  • Digital
    edited by Allison R. Kermode.
    Digital : Springer Protocols2011
    "Understanding seed-related processes is of major social, environmental, and economic concern. The viability and vigor of seeds are the very basis for sustainable agriculture and forestry, and comprehending the molecular and cellular events underlying these processes will become increasingly important to many economical sectors and for species that provide the world's food supply. Seed Dormancy: Methods and Protocols covers analytical methods and approaches which have already lead to significant advances in the understanding of seed dormancy and germination. Chapters cover explanations of processes leading to the induction, maintenance, and termination of seed dormancy, the classification of different dormancy types, as well as an overview of protocols used for dormancy-termination of seeds of conifer species. This volume emphasizes methods essential for abscisic acid (ABA) analyses, including methods that have been important for receptor identification, analyses of ABA-catabolizing enzymes (the 8'-hydroxylases), and identification of novel signal transduction components, interacting partners, and/or response factors. The volume closes by addressing the development of new technologies, including spectroscopic methods (some of which allow for non-destructive sampling) as well as highly effective tissue-printing methods for seed dormancy research. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls."--Publisher's description.
  • Print
    Augustus A. White III, with David Chanoff.
    Print2011
    Status: Not Checked OutLane Catalog Record
    "... Use[s] extensive research and interviews with leading physicians to show how subconscious stereotyping influences doctor-patient interactions, diagnosis, and treatment"--From publisher description.
  • Digital
    editors John L. Young [and others].
    Digital : NCI2001-
  • Digital
    Jane W. Ball, Joyce E. Dains, John A. Flynn, Barry S. Solomon, Rosalyn W. Stewart.
    Digital : ClinicalKey2014
    With a strong patient-centered approach to care and an author team comprised of nurses and physicians, Seidel's Guide to Physical Examination, 8th Edition, addresses teaching and learning health assessment in nursing, medical, and a wide variety of other health-care programs, at both undergraduate and graduate levels. This new edition offers an increased focus on evidence-based practice and improved readability, along with integrated lifespan content and numerous special features such as Clinical Pearls and Physical Variations, Functional Assessment, and Staying Well boxes. Evidence-Based Practice in Physical Examination boxes supply you with current data on the most effective techniques for delivering quality patient care.Clinical Pearls lend insights and clinical expertise to help you develop clinical judgment skills.Functional Assessment boxes present a more holistic approach to patient care that extends beyond the physical exam to patients' functional ability.Staying Well boxes focus you on patient wellness and health promotion. Risk Factor boxes provide opportunities for patient teaching or genetic testing for a variety of conditions.Differential diagnosis content offers you an understanding of how disease presentations vary and specific information for how to make diagnoses from similar abnormal findings.Abnormal Findings tables equip you with a quick, illustrated reference that allows for comparisons of various abnormalities along with key symptoms and underlying pathophysiology.Sample Documentation boxes clarify appropriate professional language for the process of recording patient assessment data.
  • Print
    Jerome Engel Jr.
    Print2013
    Status: Not Checked OutLane Catalog Record
    Terminology and classifications -- Perspectives -- Mechanisms of neuronal excitation and synchronization -- Basic mechanisms of seizures and epilepsy -- Causes of human epilepsy -- Epileptic seizures -- Epilepsy syndromes -- Epileptogenesis -- Periictal phenomena -- Status epilepticus -- Chronic behavioral disturbances -- Diagnostic evaluation -- Differential diagnosis -- General principles of treatment -- Antiseizure drugs -- Nonpharmacological therapy of seizures -- Social management.
  • Digital
    Mohamad Z. Koubeissi, Amer Alshekhlee, Prachi Mehndiratta, editors.
    Digital : Springer2015
    Chapter 1- Epidemiology of Seizures and Epilepsy in Cerebrovascular Disease -- Chapter 2: Seizures in Ischemic Stroke -- Chapter 3: Seizures in Intracerebral Hemorrhage -- Chapter 4: Seizures in Subarachnoid Hemorrhage -- Chapter 5: Seizures in subdural hematoma -- Chapter 6: Seizures in Cerebral Cavernous Malformations -- Chapter 7: Seizures in Arteriovenous Malformations -- Chapter 8: Seizures in Cerebral Venous Sinus Thrombosis -- Chapter 9: Pediatric Stroke and Seizures -- Chapter 10: Medical Management of Seizures in Cerebrovascular Disorders.
  • Digital
    edited by Panayiotis Varelas.
    Digital : Springer2010
    Presentation and pathophysiology of seizures in the critical care environment: an overview -- Diagnosing and monitoring seizures in the ICU: the role of continuous EEG for detection and management of seizures in critically ill patients -- Stroke and critical care seizures -- Traumatic brain injury and seizures in the ICU -- Brain tumors and ICU seizures -- Global hypoxia-ischemia and critical care seizures -- Seizures in fulminant hepatic failure, multiorgan failure, and endocrine crisis -- Seizures in organ transplant recipients -- Extreme hypertension, eclampsia and critical care seizures -- Infection or inflammation and ICU seizures -- Electrolyte disturbances and critical care seizures -- Alcohol-related seizures in the intensive care unit -- Drug-induced seizures in critically ill patients -- Critical care seizures related to illicit drugs and toxins -- Management of status epilepticus and critical care seizures.
  • Digital
    edited by Charlotte H. Clarke, Diane L. Bankert McCarthy.
    Digital : Springer Protocols2012
    Optimized conditions for a quantitative SELDI TOF MS protein assay -- Solid-phase fractionation strategies applied to proteomics investigations -- Data processing and analysis using ProteinChip(r) data manager software -- Purification and identification of candidate biomarkers discovered using SELDI-TOF ms -- Biomarker discovery in serum/plasma using surface enhanced laser desorption ionization time of flight (SELDI-TOF) mass spectrometry -- Plasma proteomic profiling of pediatric osteosarcoma -- Profiling of urine using ProteinChip(R) technology -- Protein profiling of cerebrospinal fluid -- SELDI-TOF mass spectrometry-based protein profiling of tissue samples for toxicological studies -- Proteomic analysis of skeletal muscle tissue using SELDI-TOF ms: Application to disuse atrophy -- Profiling cervical lavage fluid by SELDI-TOF mass spectrometry -- Isolation and proteomic analysis of platelets by SELDI-TOF MS -- Using SELDI-TOF mass spectrometry on amniotic fluid and for clinical proteomics and theranostics in disorders of pregnancy -- High throughput profiling of serum phosphoproteins/peptides using the SELDI-TOF-MS platform -- Analysis of protein-protein interaction using proteinchip array-based SELDI-TOF mass spectrometry -- Quantitation of amyloid beta peptides in CSF by surface enhanced MALDI-TOF.
  • Digital
    [edited by] Robert J. Alpern, Steven C. Herbert.
    Digital : ScienceDirect2008
  • Digital
    edited by Robert J. Alpern, Orson W. Moe, Michael Caplan.
    Digital : ScienceDirect2012
    Digital : ClinicalKey2013
    Section I. Epithelial and Nonepithelial Transport and Regulation -- Section II. Structural and Functional Organization of the Kidney -- Section III. Fluid and Electrolyte Regulation and Dysregulation -- Section IV. Pathophysiology of Renal Disease.
  • Digital
    first draft prepared by Mr. Philip Copestake.
    Digital : WHO2010
    Print2010
  • Digital
    edited by Hans E. Kaiser and Aejaz Nasir ; associate editor, Nelly Adriana Nasir.
    Digital : Springer2008
  • Digital
    Stephen E. Fienberg, David C. Hoaglin, editors.
    Digital : Springer2006
  • Print
    Glover, Edward.
    Status: Not Checked OutLane Catalog Record
    v. 1. On the early development of mind -- v. 2 The roots of crime.
  • Print
    Michael E. DeBakey ; edited by Alan P. Stolz and Matt D. Price.
    Print2008
    Status: Not Checked OutLane Catalog Record
    The role of government in health care: a societal issue -- A simple continuous-flow blood transfusion instrument -- Carcinoma of the lung -- The development of vascular surgery -- Surgical treatment of aneurysm of abdominal aorta by resection and restoration of continuity with homograft -- Successful resection of aneurysm of thoracic aorta and replacement by graft -- Successful carotid endarterectomy for cerebrovascular insufficiency: nineteen-year follow-up -- Surgical considerations of dissecting aneurysm of the aorta -- Aneurysm of thoracoabdominal aorta involving the celiac, superior mesenteric, and renal arteries: report of four cases treated by resection and homograft replacement -- Patterns of atherosclerosis and their surgical significance -- Left ventricular bypass pump for cardiac assistance: clinical experience -- Human cardiac transplantation -- Aortocoronary bypass with saphenous vein graft: seven-year follow-up.
  • Digital
    Gavin Bowyer, Andrew Cole, editors.
    Digital : Springer2014
    Selected References in Trauma and Orthopaedics provides a selection of references from the Trauma and Orthopedic literature, aimed at the surgeon preparing for the Intercollegiate Specialty Board examination, and similar end-of training examinations in other countries. It is the perfect guide for examiners and trainers who are preparing their trainees for the examination, as well as providing a literature basis for their own practice. Selected References in Trauma and Orthopaedics presents the classical papers underlying current practice as well as recent publications which have brought about innovation, clarified pathology or demonstrated outcomes. The references are presented with a brief summary which allows the reader to access a literature review, with the use of online resources, with the key references already identified.
  • Digital
    Compiled for the Committee on Aging.
    Digital : Google Books1955-
    Print1955-
  • Print
    Linda Seligman and Lourie W. Reichenberg.
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    Peter H.J. van der Voort, Hendrick K.F. van Saene, editors.
    Digital : Springer2007
  • Digital
    Antonio Cano Sanchez, Joaquim Calaf i Alsina, José-Luis Dueñas-Díez (editors).
    Digital : Springer2006
  • Digital
    Hao Li.
    Digital2015
    Malaria, a disease that affects millions of people in the world, is caused by the parasitic protozoan Plasmodium spp. In particular, Plasmodium falciparum leads to the most severe form of malaria and is especially lethal to young children. Although current anti-malaria medications are effective chemotherapeutics, the parasite can rapidly develop resistance to these agents and cases of resistance to even the first line of anti-malaria treatments have been reported. This increases the urgency to identify new malaria drugs and drug targets. In this thesis, I will first describe our efforts at identifying epoxyketone proteasome inhibitors that can attenuate Plasmodium growth with overall low host toxicity. We then synthesized activity based probes to monitor Plasmodium proteasome activity and together with subunit selective proteasome inhibitors, we assessed the importance of individual catalytic sites of the proteasome for parasite survival. We then screened covalent and non-covalent inhibitors against the catalytic site most crucial for parasite viability. Finally, we profiled the substrate cleavage signature of the P. falciparum proteasome and compared it to the human proteasome. We designed peptidic inhibitors based on dominant amino acid residues in the cleavages unique to P. falciparum proteasome. The inhibitor studies, along with cryo-electronmicroscopy structural elucidation of inhibitor bound Plasmodium proteasome, led us to the finding that the host and parasite [beta] 2 proteasome subunit have major differences in their substrate binding site. We then demonstrated how this difference could be exploited for design of potent and parasite selective proteasome inhibitor that was safely dosed in vivo. Taken together, this suggests that the Plasmodium proteasome is sufficiently different from the human proteasome for selective inhibition and promises to be an effective target for anti-malarial therapy.
  • Digital
    edited by Stanley P.L. Leong, Yuko Kitagawa, Masaki Kitajima.
    Digital : Springer2005
    Print2005
  • Digital
    Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev, editors.
    Digital : Springer2012
    Pt. 1. Selenocysteine biosynthesis and incorporation into protein -- pt. 2. Selenoproteins and selenoproteins in health -- pt. 3. Selenium and selenoproteins in human health -- pt. 4. Mouse models for elucidating the role of selenium and selenoproteins in health.
  • Digital
    editors, Gary S. Banuelos, Z.-Q. Lin, Xuebin Yin.
    Digital : CRCnetBASE2014
  • Digital
    edited by Carlos López-Larrea.
    Digital : Springer2012
    Print2012
    The origin of the bacterial immune response / Jesús Martínez Borra, Segundo González, and Carlos López Larrea -- The evolution of self during the transition to multicellularity / Aurora M. Nedelcu -- Glyconectin glycans as the self assembling nano-molecular-velcrosystem mediating self-nonself recognition and adhesion implicated in evolution of multicellularity / Gradimir N. Misevic, Nikola Misevic, and Octavian Popescu -- Neglected biological features in cnidarians self-nonself recognition / Baruch Rinkevich -- Intracellular inflammatory sensors for foreign invaders and substances of self-origin / Nao Jounai, Kouji Kobiyama, and Fumihiko Takeshita -- Nonself perception in plant innate immunity / Ian A. Dubery, Natasha M. Sanabria, and Ju Chi Huang -- How did flowering plants learn to avoid blind date mistakes? : self-incompatibility in plants and comparisons with nonself rejection in the immune response / Philip J. Kear and Bruce McClure -- Signaling pathways that regulate life and cell death : evolution of apoptosis in the context of self-defense / Cristina Muñoz Pinedo -- Sensing necrotic cells / Yasunobu Miyake and Sho Yamasaki -- Sensing endoplasmic reticulum stress / Vipul M. Parmar and Martin Schröder -- Autophagy and self-defense / Jesús Martínez-Borra and Carlos López-Larrea -- Viruses and host evolution : virus-mediated self identity / Louis Villarreal -- The evolution of adaptive immunity / Nadia Danilova -- Epigenetic code and self-identity / Vincanzo Calvanese, Ester Lara and Mario F. Fraga -- Viral immunomodulatory proteins : usurping host genes as a survival strategy / Pablo Engel and Ana Angulo -- The emergence of the major histocompatibility complex / Jesús Martínez-Borra and Carlos López-Larrea -- MHC signaling during social communication / James S. Ruff ... [et al.].
  • Digital
    Kacey Layn Sachen.
    Digital2012
    Follicular lymphoma (FL) is a monoclonal B cell malignancy and each tumor expresses a unique cell surface immunoglobulin (Ig) molecule that can potentially recognize antigens and/or transduce signals into the tumor cell. There is evidence that the functions of antigen binding and signaling are important for maintaining the survival of the FL tumor cells. The Ig variable region genes of these tumors undergo somatic hypermutation and yet functional Ig molecules are preserved. Additionally, the distribution of replacement and silent mutations within the Ig V genes implies a selective force to preserve their ability to bind antigens. We screened the tumor-derived Ig from a large collection of FL tumors and observed a high frequency of reactivity against human tissue antigens. For one FL patient, the recognized self-antigen was identified as myoferlin. This patient's tumor cells bound myoferlin in proportion to their level of surface Ig, and the binding to myoferlin was preserved despite ongoing IgV region somatic mutation. These findings indicate that FL may often be driven by auto-antigens. The preservation of antigen recognition despite ongoing somatic hypermutation suggests a functional positive selective pressure for tumors to maintain the ability to recognize antigens.
  • Print
    edited by Michael S. Gordon.
    Status: Not Checked OutLane Catalog Record
  • Digital
    by Yousaf Ali.
    Digital : Springer2009
  • Digital
    T. Mark Harwood, Luciano L'Abate.
    Digital : Springer2010
    What constitutes self-help in mental health and what can be done to improve it? -- The self-help movement in mental health : from passivity to interactivity -- Distance writing : helping without seeing participants -- Bibliotherapy -- Online support groups and therapy -- Manuals for practitioners -- Anxiety disorders -- Mood disorders -- Eating disorders : anorexia, bulimia, and obesity -- Addictive behaviors -- Personality disorders -- Severe psychopathology -- Medical conditions -- Who benefits by self-help and why?
  • Digital
    edited by Michael Kyrios, Richard Moulding, Guy Doron, Sunil S. Bhar, Maja Nedeljkovic, Mario Mikulincer ; foreword by Aaron T. Beck.
    Digital : Cambridge2016
  • Print
    Lou Peveto Scott.
    Print1979-
    Status: Not Checked OutLane Catalog Record
    v. 1, Body structure and function, nutrition and food management, basic pharmacology and drug therapy ; v. 2, Roles and responsibilities in nursing health ; v. 3, Medical and surgical nursing, mental illness ; v. 4, Mother and newborn, the well and sick child, communicable diseases.
  • Digital
    Jürgen Streeck.
    Digital : Cambridge2017
    "This book portrays one day in the communicative life of the owner of an auto repair-shop in Texas. He walks, looks, points, shows and explains engines, makes sense by gesture, speaks, manages, makes his life-world, and in the process reproduces social structures and himself as individual. Self-Making Man is the first comprehensive study of a communicating person; it reveals socially shared and personal practices, as well as improvisational actions by which a person inhabits and makes sense of the world with others. After decades of discussion on embodiment, this study is the first to investigate one body in its full range of communicative activities. Grounded in phenomenology and committed to the methodological rigor of context analysis and conversation analysis, Self-Making Man departs radically from contemporary research practice: it shows that, to take embodiment in human interaction seriously, we must conceive of it as individuation and organic, self-sustaining life: as autopoeisis."--Page 4 of cover.
  • Digital
    Sabine Bährer-Kohler, (ed).
    Digital : Springer2009
  • Print
    Ancowitz, Nancy.
    Status: Not Checked OutLane Catalog Record
  • Digital
    Si Hui Tan.
    Digital2014
    Among the myriad of roles that Wnts play in biology, one of its most well-known functions is as a self-renewal signal for stem and progenitor cells. As we delve deeper into studying the mechanism(s) by which Wnt signaling effects a self-renewing outcome on the stem/progenitor cells, knowing where the Wnts come from becomes an imperative. In other words, what are the niche cells? It has been difficult to study the Wnt-producing niches as the Wnt family comprises of as many as 19 functionally redundant proteins, rendering loss-of-function experiments of individual Wnt genes liable to muted phenotypes, if any. The bone field is a prime example where sparingly little is known about the Wnt producers, even though there has been intensive studies on the Wnt responders and the functions of Wnt signaling in the osteolineage cells. Efforts to investigate how Wnts secreted by specific sources contribute to osteogenesis have just begun due to the recent availability of tools that allow for targeting of the post-translational processes necessary for Wnt secretion. Hence, we set out to identify the Wnt producers during bone development and their role in osteogenesis. Using a combination of in situ hybridization, lineage tracing and in vivo genetics, we found that osteolineage precursors direct their own self-renewal by producing their own Wnts and responding to them, thus setting up an autocrine Wnt signaling loop. This is interesting because Wnt signaling has generally been thought to promote osteogenic differentiation, and has not been associated with the maintenance of immature populations. More importantly, we are starting to unravel the molecular basis for how osteolineage precursors determine their own behavior. While Wnt signaling has been shown to regulate the stem/progenitor cells of numerous tissues, its involvement in many other tissues and cell types, the thymic epithelium for example, is still unclear. Hence, we postulated that Wnt signaling could regulate the self-renewal of the stem/progenitors of thymic epithelial cells (TECs). Indeed, through transplantation, we found that Wnt-responsiveness enriches for TEC progenitors that can create an ectopic thymus microenvironment capable of supporting T cell development, which is the first demonstration of a transplantable functional postnatal TEC population. Complementary to the transplantation study, we also performed lineage tracing to track the fates of Wnt-responsive TEC stem/progenitor cells. Unexpectedly, we found that the cortical lineage-restricted TEC (cTEC) progenitor is regulated by Wnt signaling, while other progenitors like the medullary lineage-restricted TEC progenitor are not. Hence, we have uncovered the first instance of differential regulation of the TEC progenitor populations. In addition, we also present the first conclusive evidence that cTEC progenitors exist, and in vivo proof that they contribute to cTEC maintenance over the long term. Hence, based on the status of Wnt signaling response, we can delineate cell fates and lineage potential of the various progenitor populations in the thymic epithelium. In summary, we have implicated Wnt signaling in the self-renewal of two populations whose self-renewal mechanisms were previously unclear -- the osteolineage precursors and cTEC progenitors. In the process, we discovered possible ways by which these cells maintain their identity, and more importantly, how Wn3t signaling specifically contributes to the maintenance of the bone and thymus. As the fields proceed to learn more about the how Wnt signaling promotes self-renewal, it is also important to take the knowledge to a broader perspective and ask, how does the tissue ensure which cells are able to respond to Wnt signaling and which are not, especially in contexts where Wnt signaling has multiple functions in one tissue. By following the basic principle of identifying the Wnt producers, Wnt responders, and possibly the Wnt inhibitors, we will achieve a more complete understanding of Wnt signaling's role at the tissue level, and eventually, at the level of the organism.
  • Digital
    Agota Szende, Bas Janssen, Juan Cabases, editors.
    Digital : Springer2014
    Introduction / Juan M. Cabases and Rosalind Rabin -- Data and Methods / Bas Janssen, Agota Szende, and Juan Manuel Ramos-Goni -- Population Norms for the EQ-5D / Bas Janssen and Agota Szende -- Cross-Country Analysis of EQ-5D Data / Agota Szende and Bas Janssen -- Socio-demographic Indicators based on EQ-5D / Agota Szende and Bas Janssen -- Annex 1: EQ-5D population norms - National surveys -- Annex 2: EQ-5D population norms - Regional surveys -- References -- Index.
  • Digital
    by Matteo Conti.
    Digital : Springer2008
  • Digital
    [edited by] Edward R. Laws Jr., Jason Sheehan.
    Digital : Thieme eNeurosurgery2011
    "Edward Laws and Jason Sheehan have edited the first comprehensive guide to the management of the large varieties of pathologies that arise in the sellar and parasellar area. Over the past two decades change in management practices have been underpinned by a better understanding of the nature of the pathology, improved imaging and a refinement of both surgical and radiation therapy techniques. The location of the sellar and parasellar region has challenged neurosurgeons (and radiotherapists) to develop innovative refined approaches to the region, often using the best of skull base, endoscopic and microsurgical techniques. These have been utilized within the context of an improved understanding of the pathology, with the imperative that the treatment (or therapy) must optimize control of the pathology, whilst minimizing morbidity"--Provided by publisher.
  • Print
    edited by Hans Selye.
    Print1979-
  • Digital
    Saeed Hassanpour.
    Digital2012
    It is well known that the volume of biomedical literature is growing exponentially and that scientists are being overwhelmed when they sift through the scope and diversity of this unstructured knowledge to find relevant information. Prior work on addressing this problem has focused on methods to search for relevant publications and to identify relevant parts of publications. There has been much less research on methods that assist in extracting knowledge from biomedical literature. To tackle this challenge, I present a novel method to support the acquisition of structured knowledge from unstructured text. I have applied my method to support the challenge of identifying rule-based definitions of disease phenotypes. Because background knowledge of complex and diverse medical conditions is critical to undertaking information extraction, I have developed a semantic-based approach. Specifically, I use existing background knowledge to incorporate domain-relevant semantics, such as semantic similarity and rules, into a method for finding publications and the parts of texts within that contain knowledge about phenotype definitions and for identifying the rule or rule format that correctly encodes a phenotype. I have evaluated my method in the autism phenotyping domain, and found that incorporating structured domain knowledge into information extraction provides better accuracy and higher relevance of results than alternative term-based approaches. My novel method can help scientists to rapidly identify and formalize the complex domain knowledge that is emerging in published research findings. My method is also widely applicable to other information extraction challenges where there is a need to accurately extract computer-interpretable definitions, constraints, and policies from text.
  • Digital
    Valeria Ugazio ; translated by Richard Dixon.
    Digital : ProQuest Ebook Central2013Limited to 1 simultaneous users
    Introduction -- 1. The construction of psychopathological disorders in intersubjective contexts -- Part I. The Theorectical Model -- 2. Family sematic polarities -- Part II. Semantics and Pscyhopathologies -- 3. Semantics of freedom and phobic disorders -- 4. Between good and evil: obsessive-compulsive disorders -- 5. The semantics of power: anorexia, bulimia, and other eating problems -- 6. Depression: denied belonging -- Conclusion: Therapeutic Perspectives -- 7. Family semantics and the therapeutic relationship.
  • Digital
    edited by Christopher J.O. Baker and Kei-Hoi Cheung.
    Digital : Springer2007
  • Print
    Dean Allemang, James Hendler.
    Print2008
  • Digital
    edited by R. Jeroen Pasterkamp.
    Digital : Springer2007
    Print2007
    The CRMP family of proteins and their role in Sema3A signaling / Eric F. Schmidt and Stephen M. Strittmatter -- GTPases in semaphorin signaling / Andreas W. Püchel -- Intracellular kinases in semaphorin signaling / Aminul Ahmed and Britta J. Eickholt -- Mical flavoprotein monooxygenases : structure, function and role in semaphorin signaling / Sharon M. Kolk and R. Jeroen Pasterkamp -- Signaling of secreted semaphorins in growth cone steering / Sangwoo Shim and Guo-li Ming -- Modulation of semaphorin signaling by IG superfamily cell adhesion molecules / Ahmad Bechara ... [et al.] -- Proteoglycans as modulators of axon guidance cue function / Joris de Wit and Joost Verhaagen -- Semaphorin signals in cell adhesion and cell migration : functional role and molecular mechanisms / Andrea Casazza, Pietro Fazzari, and Luca Tamagnone -- Semaphorin signaling during cardiac development / Toshihiko Toyofuku and Hitoshi Kikutani -- Semaphorin signaling in vascular and tumor biology / Gera Neufeld ... [et al.].
  • Print
    Kunjumon I. Vadakkan.
    Print2010
    Status: Not Checked OutLane Catalog Record
    "The semblance hypothesis explains how associative memory can result from the multidimensional semblance of activity from a specific set of presynaptic terminals at different orders of neurons. The hypothesized basic units are then examined for their feasibility to explain various physiological and pathological conditions of the nervous system, ranging from physiological time-scales of memory retrieval to plausible explanation for long term potentiation (LTP)"--Back cover.
  • Digital
    Patrick Haggard and Baruch Eitam.
    Digital : OSO2015
    Volition. Time to act : the dynamics of agentive experiences / Elisabeth Pacherie -- Deconstructing voluntary action : unconscious and conscious component processes / Lara Krisst, Carlos Montemayor, and Ezequiel Morsella -- Action control by if-then planning : explicating the mechanisms of strategic automaticity in regard to objective and subjective agency / Torsten Martiny-Huenger, Sarah E. Martiny, and Peter M. Gollwitzer -- Neural correlates of intentions / Roee Gilron, Shiri Simon, and Roy Mukamel -- Explicit and implicit beliefs, attitudes, and intentions : the role of conscious and unconscious processes in human behavior / Icek Ajzen and Nilanjana Dasgupta -- The neural basis underlying the experience of control in the human brain / Lauren A. Leotti, Catherine Cho, and Mauricio R. Delgado -- Goals and the sense of agency : the case of goal conflicts / Tali Kleiman -- Determining authorship. Inference processes underlying the human experience of agency over operant actions / Myrthel Dogge and Henk Aarts -- Agency and outcome prediction / Antje Gentsch and Simone Schütz-Bosbach -- The relations between agency and body-ownership : additive or independent? / Manos Tsakiris -- The innate experience of self-agency / Philippe Rochat -- Motivation from control : a response selection framework / Noam Karsh and Baruch Eitam -- Beyond authorship. Comparators and weightings : neurocognitive accounts of agency / Matthis Synofzik -- Action control and the sense of agency / Bernhard Hommel -- Control and truth working together : the agentic experience of "going in the right direction" / E. Tory Higgins -- Disturbances. Sense of agency and its disruption : clinical and computational perspectives / Paul Fletcher and Aikaterini Fotopoulou -- Action generation, intention, and agency in motor and body awareness deficits / Anna Berti, Francesca Garbarini, and Lorenzo Pia -- Disorders of volition from neurological disease : altered awareness of action in neurological disorders / James B. Rowe and Noham Wolpe.
  • Digital
    edited by Carlos López-Larrea.
    Digital : Springer2012
    Print2012
    Thermosensor systems in eubacteria / Wolfgang Schumann -- Molecular plant volatile communication / Jarmo K. Holopainen and James D. Blande -- Primary processes in sensory cells : current advances / Stephan Frings -- Chemical communication in insects : the peripheral odor coding system of Drosophila melanogaster / Narelle E. Tunstall and Coral G. Warr -- Eusocial evolution and the recognition systems in social insects / Michelle O. Krasnec and Michael D. Breed -- Odor and pheromone sensing via chemoreceptors / Minghong Ma -- Identifying self- and nonself-generated signals : lessons from electrosensory systems / Angel Ariel Caputi and Javier Nogueira -- Magnetoreception / Roswitha Wiltschko and Wolfgang Wiltschko -- The molecular basis of mechanosensory transduction / Kara L. Marshall and Ellen A. Lumpkin -- The evolution of vertebrate color vision / Gerald H. Jacobs -- Transforming the vestibular system one molecule at a time : the molecular and developmental basis of vertebrate auditory evolution / Jeremy S. Duncan and Bernd Fritzsch -- Neurobiology of sociability / Heather K. Caldwell -- Changing senses : chemosensory signaling and primate evolution / Emily R. Liman -- Molecules and mating : positive selection and reproductive behavior in primates / Leslie A. Knapp and Simeon H.S. Innocent -- Immune systems evolution / Ramón M. Rodríguez, Antonio López Vázquez and Carlos López Larrea -- Involvement of sirtuins in life-span and aging related diseases / Ulrich Mahlknecht and Barbara Zschoernig -- Molecular diversity of Dscam and self-recognition / Lei Shi and Tzumin Lee -- The neural basis of semantic and episodic forms of self-knowledge : insights from functional neuroimaging / Arnaud D'Argembeau and Eric Salmon -- Hallmarks of consciousness / Ann B. Butler.
  • Digital
    Andrzej T. Slominski...[et al.].
    Digital : Springer2012
    Introduction -- Biogenic Amines in the Skin -- Melatoninergic System in the Skin -- Cutaneous Cholinergic System -- Corticotropin Signaling System in the Skin -- Steroidogenesis in the Skin -- Equivalent of Hypothalamo-Pituitary-Adrenal Axis in the Skin -- Cutaneous Secosteroidal System -- Equivalent of Hypothalamic-Pituitary-Thyroid Axis -- Cutaneous Opioid System -- Cutaneous Endocannabinoid System -- Perspectives.
  • Digital
    Dan G. Cacuci.
    Digital : CRCnetBASEv. 1, 2003
    Digital : CRCnetBASEv. 2, 2005
    v. 1. Theory / Dan G. Cacuci -- v. 2. Applications to large-scale systems / Dan G. Cacuci, Mihaela Ionescu-Bujor, Ionel Michael Navon.
  • Digital
    edited by Benjamin Bonavida.
    Digital : Springer2008
  • Digital
    edited by Numa Dancause, Sylvie Nadeau and Serge Rossignol.
    Digital : ScienceDirect2015
  • Digital
    Wolfgang Meyerhof, Ulrike Beisiegel, Hans-Georg Joost, editors.
    Digital : Springer2010
    Print2010
  • Digital
    Brendan J. Canning, Domenico Spina, editors ; contributors, R. Baron ... [et al.].
    Digital : Springer2009
  • Digital
    by Jozef J. Zwislocki.
    Digital : Springer2009
  • Digital
    Gerald E. Miller.
    Digital2006
  • Digital
    Friedrich G. Barth, Patrizia Giampieri-Deutsch, Hans-Dieter Klein, Editors.
    Digital : Springer2012
    "Sensory perception : mind and matter aims at a deeper understanding of the many facets of sensory perception and their relations to brain function and cognition. It is an attempt to promote the interdisciplinary discourse between the neurosciences and psychology, which speaks the language of cognitive experiences, and philosophy, which has been thinking about the meaning and origin of consciousness since its beginning. Leading experts contribute to such a discourse by informing the reader about exciting modern developments, both technical and conceptual, and by pointing to the big gaps still to be bridged. The various chapters provide access to scientific research on sensory perception and the mind from a broad perspective, covering a large spectrum of topics which range from the molecular mechanisms at work in sensory cells to the study of the unconscious and to neurophilosophy"--Publisher.
  • Digital
    [edited by] Carlo Cristini, Alberto Ghilardi ; presentazione a cura di Marcello Cesa-Bianchi.
    Digital : Springer2009
  • Digital
    Ahuja, Satinder.
    Digital : ScienceDirectv. 1-, 1998-
  • Digital
    Guillermo Ortiz-Ruiz ... [et al.], editors.
    Digital : Springer2006
  • Digital
    Simon V. Baudouin, ed.
    Digital : Springer2008
  • Digital
    edited by Nicasio Mancini.
    Digital : Springer Protocols2015
    Microbiological diagnosis of sepsis : the confounding effects of a "Gold Standard" / Nicasio Mancini, Roberto Burioni, and Massimo Clementi -- Pathophysiological aspects of sepsis : an overview / Yong-Ming Yao [and 3 others] -- Clinical aspects of sepsis : an overview / Giacomo Monti [and 4 others] -- Technical improvements in culturing blood / Giacomo Pardini -- Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF/MS)-based identification of pathogens from positive blood culture bottles / Philippe Lagacé-Wiens -- Bacterial and fungal DNA extraction from positive blood culture bottles : a manual and an automated protocol / Minna Mäki -- Broad-range PCR in the identification of bacterial and fungal pathogens from positive blood culture bottles : a sequencing approach / Yoshitomo Morinaga and Katsunori Yanagihara -- Identification of bacterial and fungal pathogens from positive blood culture bottles : a microarray-based approach / Teresa Raich and Scott Powell -- Detection of carbapenemases using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) meropenem hydrolysis assay / Jaroslav Hrabák -- Molecular detection of antibiotic resistance genes from positive blood cultures / Musa Y. Hindiyeh [and 4 others] -- Bacterial and fungal DNA extraction from blood samples : manual protocols / Michael G. Lorenz, Helge Mühl, and Claudia Disqué -- Bacterial and fungal DNA extraction from blood samples : automated protocols / Michael G. Lorenz, Claudia Disqué, and Helge Mühl -- Broad-range PCR for the identification of bacterial and fungal pathogens from blood : a sequencing approach / Eva Leitner and Harald H. Kessler -- Real-time PCR-based identification of bacterial and fungal pathogens from blood samples / Madeleine Mai [and 6 others] -- Host response biomarkers in the diagnosis of sepsis : a general overview / Marianna Parlato and Jean-Marc Cavaillon -- Host response biomarkers in sepsis : the role of procalcitonin / Jean-Louis Vincent, Marc Van Nuffelen, and Christophe Lelubre -- Host response biomarkers in sepsis : overview on sTREM-1 detection / Jérémie Lemarié, Damien Barraud, and Sébastien Gibot -- Host response biomarker in sepsis: suPAR detection / Evangelos J. Giamarellos-Bourboulis and Marianna Georgitsi -- Clinical diagnosis of sepsis and the combined use of biomarkers and culture- and non-culture-based assays / Frank Bloos.
  • Digital
    edited by Jordi Rello, Marcos I. Restrepo.
    Digital : Springer2008
  • Digital
    volume editors, Heiko Herwald, Arne Egesten.
    Digital : Karger2011
    Roger C. Bone, MD and the evolving paradigms of sepsis / Balk, R. -- Clinical aspects of sepsis / Holub, M.; Závada, J. -- Virulence factors of gram-negative bacteria in sepsis with a focus on Neisseria meningitidis / Livorsi, D.J.; Stenehjem, E.; Stephens, D.S. -- Molecular mechanisms of sepsis / Russell, J.A. ... [et al.] -- Pro-inflammatory mechanisms in sepsis / Chong, D.L.W.; Sriskandan, S. -- Anti-inflammatory mechanisms of sepsis / Shubin, N.J.; Monaghan, S.F.; Ayala, A. -- Regulation of pro- and anti-inflammatory host responses / van der Poll, T.; van Zoelen, M.A.D.; Wiersinga, W.J. -- Future perspectives on regulating pro- and anti-inflammatory responses in sepsis / Delsesto, D., Opal, S.M.
  • Digital
    Jordi Rello, Jeffrey Lipman, Thiago Lisboa, editors.
    Digital : Springer2012
  • Digital
    edited by Amy S. Gladfelter.
    Digital : ScienceDirect2016
  • Digital
    by Eugene V. Koonin and Michael Y. Galperin.
    Digital : NLM2003.
  • Digital
    by Kun-Mao Chao, Louxin Zhang.
    Digital : Springer2009
  • Digital
    Charles Gawad.
    Digital2014
    Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer and although outcomes have markedly improved over the past 50 years, it remains a leading cause of pediatric cancer-related morbidity and mortality. Studies have catalogued many of the recurrent genetic alterations that occur during the development of childhood ALL, but those investigations have not identified a definitive underlying etiology. Our current understanding is that childhood leukemogenesis begins with genetic changes in utero that interact with germline genetic predisposition to progress to ALL in a fraction of patients during childhood. Although secondary events that result in disease progression have not been identified, late exposure to common infections is a strong risk factor. To acquire a better understanding of childhood leukemogenesis, we leveraged the throughput of next-generation sequencing to globally evaluate the nucleic acid content of leukemia cells. Our initial study aimed to identify genomic structural rearrangements, as well as viral genomes or transcripts in ALL samples using RNA-seq. Through the development of novel experimental and computational methods, we surprisingly identified circular RNA isoforms are much more abundant than previously appreciated. Further work showed that they are present in normal human cells, other model organisms, and human plasma. Characterization of circular splicing of ASXL1, a gene commonly mutated in leukemia that contains a conserved circular isoform, found that the transcript is spliced into its circular isoform much less efficiently than its linear counterpart. However, we identified intronic repeat sequences, as well as exonic regions that iv are required for efficient circular splicing suggesting these molecules, which are estimated to comprise 1% of the human transcriptome, may have evolved distinct biological functions. We next used the single-allele readout of next-generation sequencing, as well as the automation of microfluidic devices to probe the genetic diversity of leukemia samples. We first discovered continued ongoing changes in the immunoglobulin locus of ALL cells using immune repertoire sequencing, which has helped improve ALL disease monitoring strategies. We then physically isolated and amplified the genomes of individual cells using microfluidics to identify mutation co-segregation patterns, as well as the clonal structures of ALL samples. With the experimental and clone-deciphering algorithms developed, we were able to determine that co-dominant clones are present in most patients, KRAS mutations occur late in disease development but are not sufficient for clonal dominance, and there are clone-specific punctuated cytosine mutagenesis events. The latter finding may lead back to the identification of a viral etiology, as the mutations have signature of APOBEC, a cytosine deaminase that is induced to provide innate anti-viral defense. Taken together, these studies have provided new paths to better understand general questions about posttranscriptional regulation, as well as the specific events that result in the development of childhood leukemias. Our deep characterization of linear and circular splicing has raised fundamental questions about the diversity of alternative splicing, as well as the importance of the resulting processed RNA in posttrancriptional regulation. Our high resolution dissection of clonal heterogeneity in childhood ALL has led to questions that could clarify the underlying etiology and pathogenesis, including the roles for APOBEC proteins, clonal symbiosis and competition, and the evolution of clonal structures that occurs after changes in selection pressure. It will take hard work, creativity, and continued technology development to decipher definitive roles of v posttranscriptional regulation and genomic heterogeneity in normal and malignant cellular biology.
  • Digital
    edited by Kåre Lehmann Nielsen.
    Digital : Springer Protocols2008
    SAGE and LongSAGE / Annabeth Laursen Høgh and Kåre Lehmann Nielsen -- Robust-LongSAGE (RL-SAGE) : an improved LongSAGE method for high-throughput transcriptome analysis / Malali Gowda and Guo-Liang Wang -- aRNA LongSAGE : SAGE with antisense RNA / Anna M. Heidenblut -- SuperSAGE / Hideo Matsumura ... [et al.] -- Low-cost-medium throughput Sanger dideoxy sequencing / Kåre Lehmann Nielsen -- DeepSAGE : higher sensitivity and multiplexing of samples using a simpler experimental protocol / Kåre Lehmann Nielsen -- High-resolution, genome-wide mapping of chromatin modifications by GMAT / Tae-Young Roh and Keji Zhao -- 5'- and 3'-RACEfrom LongSAGE tags / Kåre Lehmann Nielsen -- Extraction and annotation of SAGE tags using sequence quality values / Jeppe Emmersen -- Correction of technology-related artifacts in serial analysis of gene expression / Viatcheslav R. Akmaev -- Duplicate ditag analysis in LongSAGE / Jeppe Emmersen -- Statistical comparison of two or more SAGE libraries : one tag at a time / Gerben J. Schaaf ... [et al.] -- Scaling of gene expression data allowing the comparison of different gene expression platforms / Fred van Ruissen ... [et al.] -- Clustering analysis of SAGE transcription profiles using a Poisson approach / Haiyan Huang, Li Cai, and Wing H. Wong -- Identifying nonspecific SAGE tags by context of gene expression / Xijin Ge and San Ming Wang.
  • Digital
    Dennis Nick Fournogerakis.
    Digital2013
    My graduate studies have been focused on two separate projects that are unified by the theme of step economy and exemplify two major concepts within step economy. The first of these is the development of new reactions or serial reactions aimed at creating ways to achieve significant molecular complexity increases in a short synthetic sequence to access targets of value. Complementary to this is the concept of function-oriented synthesis, which involves the design and synthesis of novel structures of value that contribute to our understanding of the biological effects of the compound and results in the refinement of lead structures to produce clinically more optimal candidates. Chapter 1 reviews the development of serial cycloadditions and their application in organic synthesis. Serial cycloadditions are valuable reactions for organic chemists because of the significant increase in molecular complexity observed in a single step. The review separates the collective body of work into non-catalyzed serial cycloadditions and transition metal catalyzed cycloadditions. The non-catalyzed variants can involve the combining of simple starting materials into polycyclic ring systems, but are typically limited to more activated dienes or dienophiles. The transition metal mediated processes developed more recently have utilized unactivated reaction partners but, typically, rely on complex starting substrates. This review highlights the potential opportunity to develop serial cycloadditions that combine simple unactivated reaction partners to produce scaffolds of interest. Chapter 2 discusses the development of 4-trimethylsilyl-but-2-yn-1-ol as a regioselective butatriene equivalent for serial [5+2]/vinylogous Peterson olefination/[4+2] cycloadditions to produce linear polycyclic ring systems. 4-trimethylsilyl-but-2-yn-1-ol behaves as initial 2-carbon component in the Rh-catalyzed [5+2] cycloaddition with vinylcyclopropane and then subsequently eliminates to a diene that can be utilized for further elaboration. A diverse set of dienophiles was evaluated for the second cycloaddition and both alkynes and alkenes were found to be suitable reaction partners, with up to nearly quantitative yields obtained. The reaction was utilized to access a key intermediate for proposed simplified analogs of staurosporine. Chapter 3 begins by describing the current state of the HIV pandemic and the limitations of the current therapeutic options (Highly Active Antiretroviral Therapy - HAART). The principal barrier to developing a cure for HIV is the latent reservoir that is insusceptible to HAART. The natural product prostratin is a clinical lead for a promising HIV eradication strategy that involves the deliberate activation of these latent reservoirs. Novel analogs of prostratin were synthesized and found to exhibit activity that greatly exceeded the natural product in multiple biological assays. Most impressively, a lead analog was found to potently induce HIV expression in patient samples from HIV-infected individuals on suppressive HAART. Chapter 4 delves into the design, synthesis, and evaluation of 2nd-generation analogs of prostratin. These analogs were inspired by the realization of a key intramolecular hydrogen bond in prostratin and can be accessed in a more step-economical fashion than the original analogs because they circumvented a problematic deoxygenation step in the original synthesis. The new analogs that incorporated ether functionality at C12 of prostratin were found to have higher affinities for PKC, the presumed biological target for prostratin, and more potent induction of latent HIV in vitro and ex vivo. Finally, Chapter 5 describes the further manipulation of the prostratin scaffold in hopes of obtaining properties of a clinically optimized agent. Novel transformations on the scaffold are reported and preliminary biological evaluation of the new analogs is discussed. Based on these results, new information was obtained about the tolerability of the protein binding pocket for certain modifications and this will facilitate the future development of novel PKC modulators.
  • Print
    Abbie Griffin, Raymond L. Price, Bruce A. Vojak
    Status: Not Checked OutLane Catalog Record
  • Print
    R.A.M. Case ... [et al.].
    Status: Not Checked OutLane Catalog Record
    v. 1. England and Wales, 1911-70 : Deaths and death rates by sex, age, site, and calendar period.
  • Digital
    edited by Richard N. Kocsis.
    Digital : Springer2007
    Pt. I. The psychology of serial violent crimes. Normalcy in behavioral characteristics of the sadistic serial killer / Jack Levin and James Alan Fox -- The compulsive-repetitive offender: behavioral patterns, motivational dynamics / Louis B. Schlesinger -- Serial juvenile sex offenders and their offenses / Jessica Woodhams, Clive Hollin and Ray Bull -- A study of offense patterns and psychopathological characteristics among recidivistic Finnish homicide offenders / Helinä Häkkänen -- Sensational and extreme interests in adolescents / Kathy E Charles and Vincent Egan -- Narcissism, sadism and loneliness: the case of serial killer Jeffrey Dahmer / George B. Palermo -- pt. 2. New dimensions to violent crime. Sexual homicide: an overview of contemporary empirical research / Leonard I. Morgenbesser and Richard N. Kocsis -- Serial killers and serial rapists: a preliminary comparison of violence typologies / Stacey L. Shipley and Bruce A. Arrigo -- Firesetting: a burning issue / Jeffrey L. Geller -- The 'gentler sex': patterns in female serial murder / Hannah Scott -- Anatomy of a mass murder: a psychological profile of Martin Bryant and the Port Arthur massacre / Ian Sale -- pt. 3. Investigative considerations to serial violent crimes. Blundering justice: a case study of the Schiedam Park Murder / Peter J. van Koppen -- Sexual (lust) homicide: definitional constructs, dynamics and investigative considerations / Janet McClellan -- Criminal profile construction and investigative procedures: a study of the Westley Dodd serial sexual murders / Ronald Turco -- Psychological skills and criminal profile accuracy / Erica P. Hodges and Kristine M. Jacquin -- Profiling and professionalization of criminal investigation / Jeffrey B. Bumgarner
  • Digital
    ed. by E.C. Seguin ...
    Digital : Google BooksFulltext (v. 1 1876)
    Digital : Google BooksFulltext (v. 2 1877)
    Digital : Google BooksFulltext (v. 3 1879)
  • Print
    Status: Not Checked OutLane Catalog Record
    Monograph 1. Unemployment insurance -- Monograph 2. Old age dependency -- Monograph 3. Health insurance -- Monograph 4. Social insurance legislation -- Monograph 5. The administration of unemployment insurance -- Monograph 6. The limitations of unemployment insurance -- Monograph 7-12. British experience with unemployment insurance -- Monograph 13. The problem of old age dependency.
  • Digital
    Alfonso Pedro Farruggio.
    Digital2013
    The "integrase" enzyme of the bacterial virus phiC31 mediates the unidirectional fusion of the phiC31 and host-bacterium genomes. This recombination reaction occurs between two specific DNA sequences (att-sites), and can be performed by the enzyme without accessory factors in a wide variety of cellular environments, including human cells. Although its primary application to date in eukaryotes has been in organisms where the native phiC31 integrase (C31-int) att-sites have been pre-introduced, C31-int can also function on certain endogenous sequences (pseudosites) in animal genomes, albeit with significantly reduced activity. The ability of C31-int to perform pseudosite integration has made it the focus of several whole-animal and tissue-culture gene-therapy studies over the past decade, as there is currently no means to safely maintain the therapeutic DNA that is delivered for gene-therapy. The focus of my graduate work has been to assist these efforts to apply C31-int for gene-therapy. Specifically, I have sought to increase our basic scientific understanding of DNA recognition by C31-int through deletion and chimera studies (Chapters 2-3), and I have also attempted to improve the implementation of C31-int applications in mammals through my contributions to applied C31-int projects (Chapters 4-6). The results from my deletion and chimera studies have helped to clarify that C31-int employs DNA binding domains that are largely modular and have also helped to lay the groundwork for a potential means to derive serine integrases with novel specificities. The results from my contributions to applied C31-int projects have made it possible to reverse the wild-type reaction in mammalian cells (Chapter 4), to produce high-quality mouse induced-pluripotent-stem cells (iPSC) with C31-int (Chapter 5), and to genetically engineer mouse iPSCs (Chapter 6). Although C31-int will still require significant engineering before it is suitable for use in human gene therapy, and although additional work will be required to fully realize the potential of our iPSC-production and -engineering scheme in human cells, my experience with C31-int and related enzymes that I describe in this dissertation has left me optimistic that these are not unreasonable goals.
  • Digital
    K.N. Michailova, K.G. Usunoff.
    Digital : Springer2006
  • Digital
    Caio Maximino.
    Digital : Springer2012
    Introduction -- Serotonin in the Nervous System of Vertebrates -- Nodal Structures in Anxiety-Like and Panic-Like Responses -- The Deakin-Graeff Hypothesis -- Topographic Organization of DRN -- General Conclusions.
  • Digital
    edited by J.M. Monti ... [et al.].
    Digital : Springer2008
  • Digital
    edited by Giuseppe Di Giovanni, Vincenzo Di Matteo and Ennio Esposito.
    Digital : ScienceDirect2008
  • Digital
    edited by Wolfgang Blenau, Universität zu Köln, Köln, Germany, Arnd Baumann, Forschungszentrum Jülich, Jülich, Germany.
    Digital : Springer Protocols2015
    Novel Approaches to Serotonin Receptor Interaction Studies -- Techniques for the Study of GPCR Heteromerization in Living Cells and Animal Models -- Organotypic Slices and Biolistic Transfection for the Study of Serotonin Receptor Function in CNS Neurons -- Dissecting a Model of Depressive-Related Phenotype and Antidepressants Effects in 129S2/SvPas Mice -- The Murine Serotonin Syndrome and the 5-HT1A Receptor: Behavioral Effects and Hypothermia -- 5-HT4 Receptor Subtype, Î2-arrestin Level, and Rapid Onset Effects of Antidepressant Drugs -- Autoshaping Memory Formation and Retention Loss: Are Serotonin and Other Neurotransmitter Transporters Involved? -- Flow Cytometry to Determine Serotonin Transporter Function in Human Peripheral Blood Cells -- Functional Genomics of Serotonin Receptors in Helminth Parasites: Elucidation of Receptor Function through RNA Interference (RNAi) -- Visualization of the Serotonin System in Drosophila Brain: Immunofluorescence and Confocal Microscopy -- Serotonin Modulates Adult Neurogenesis in an Invertebrate Model: Approaches to Receptor Localization and Function -- Immunolocalization of Serotonergic Neurons in Arthropod Developmental and Phylogenetic Neuroanatomy.
  • Digital
    edited by Amitabha Chattopadhyay.
    Digital : CRCnetBASE2007
    Quantitative imaging of serotonin autofluorescence with multiphoton microscopy / S.K. Kaushalya and Sudipta Maiti -- Monitoring receptor-mediated changes of intracellular cAMP level by using ion channels and fluorescent proteins as biosensors / Evgeni G. Ponimaskin ... [et al.] -- Membrane organization and dynamics of the serotonin1A receptor monitored using fluorescence microscopic approaches / Shanti Kalipatnapu, Thomas J. Pucadyil, and Amitabha Chattopadhyay -- Calmodulin is a 5-HT receptor interacting and regulatory protein / Justin N. Turner ... [et al.] -- Identification of novel transcriptional regulators in the nervous system / Federico Remes-Lenicov ... [et al.] -- Serotonin 2A (5-HT2A) receptor function: ligand-dependent mechanisms and pathways / Ishier Raote, Aditi Bhattacharya, and Mitradas M. Panicker -- The 5-HT1A receptor: a signaling hub linked to emotional balance / Probal Banerjee, Mukti Mehta, and Baishali Kanjilal -- Do limits of neuronal plasticity represent an opportunity for mental diseases, such as addiction to food and illegal drugs? Use and utilities of serotonin receptor knock-out mice / Valerie Compan -- Use of mice with targeted genetic inactivation in the serotonergic system for the study of anxiety / Miklos Toth.
  • Digital
    Syed Z. Ali, Edmund S. Cibas.
    Digital : Springer2012
    Introduction, Clinical and Technical Aspects-- Normal Cytology-- Reactive Mesothelial Hyperplasia-- Malignant Mesothelioma-- A Potential Litigation Diagnosis-- Metastatic Cancers-- Effusions in Children-- Abdominopelvic Washings-- Lymphocytic Effusions-- Benign Inflammatory and Other Uncommon Conditions-- Cerebrospinal Fluid.
  • Digital
    Ben Davidson, editor-in-chief ; Pınar Fırat, Claire W. Michael, editors.
    Digital : Springer2012
  • Digital
    edited by James C. Whisstock and Phillip I. Bird.
    Digital : ScienceDirect2011
    Intracellular production of recombinant serpins in yeast / Dion Kaiserman ... [et al.] -- Production of recombinant serpins in Escherichia coli / Mary C. Pearce and Lisa D. Cabrita -- Isolation and characterization of the nuclear serpin MENT / Sergei Grigoryev and Sheena McGowen -- Solving serpin crystal structures / Randy J. Read, Aiwu Zhou, and Penelope E. Stein -- Crystallography of serpins and serpin complexes / M.A. Dunstone and James Whisstock -- Serpins as hormone carriers : modulation of release / Robin Carrell, Xiaoqiang Qi, and Aiwu Zhou -- Serpin-glycosaminoglycan interactions / Chantelle M. Rein, Umesh R. Desai, and Frank C. Church -- Targeting serpins in high-throughput and structure-based drug design / Yi-Ping Chang ... [et al.] -- Development of inhibitors of plasminogen activator inhibitor-1 / Shih-Hon Li and Daniel A. Lawrence -- Bioinformatic approaches for the identification of serpin genes with multiple reactive site loop coding exons / Stefan Börner and Hermann Ragg -- Methods to measure the kinetics of protease inhibition by serpins / Anita J. Horvath ... [et al.] -- Predicting serpin/protease interactions / Jiangning Song ... [et al.] -- Amino-Terminal Oriented Mass spectrometry of Substrates (ATOMS) : N-terminal sequencing of proteins and proteolytic cleavage sites by quantitative mass spectrometry / Alain Doucet and Christopher M. Overall -- Computational methods for studying serpin conformational change and structural plasticity / Itamar Kass, Cyril F. Reboul, and Ashley M. Buckle -- Probing serpin conformational change using mass spectrometry and related methods / Yuko Tsutsui, Anindya Sarkar, and Patrick L. Wintrode -- Determining serpin conformational distributions with single molecule fluorescence / Nicole Mushero and Anne Gershenson -- Serpin polymerization in vitro / James A. Huntington and Masayuki Yamasaki -- The serpinopathies : studying serpin polymerization in vivo / James A. Irving ... [et al.].
  • Digital
    [edited by] Michael K. Skinner, Michael D. Griswold.
    Digital : ScienceDirect2005
    Print2005
  • Digital
    editor: Xijun Wang ; associate editors: Aihua Zhang, Hui Sun.
    Digital : ScienceDirect2017
  • Digital
    edited by Richard J. Simpson and David W. Greening.
    Digital : Springer Protocols2011
    Plasma biomarker discovery using 3D protein profiling coupled with label-free quantitation / Lynn A. Beer [and others] -- Intact protein separation by one- and two-dimensional liquid chromatography for the comparative proteomic separation of partitioned serum or plasma / Simon Sheng [and others] -- In-depth analysis of a plasma or serum proteome using a 4D protein profiling method / Hsin-Yao Tang, Lynn A. Beer, and David W. Speicher -- Intact-protein analysis system for discovery of serum-based disease biomarkers / Hong Wang and Samir Hanash -- Model-based discovery of circulating biomarkers / Maryann S. Vogelsang [and others] -- Low-molecular weight plasma proteome analysis using centrifugal ultrafiltration / David W. Greening and Richard J. Simpson -- High-throughput analysis of glycoproteins from plasma / Yan Li and Hui Zhang -- Minimizing preanalytical variation of plasma samples by proper blood collection and handling / Jizu Yi, David Craft, and Craig A. Gelfand -- Collection and handling of blood specimens for peptidomics / Harald Tammen and Rüdiger Hess -- Investigation of peptide biomarker stability in plasma samples using time-course MS analysis / Jizu Yi [and others] -- Biomarker validation in blood specimens by selected reaction monitoring mass spectrometry of N-glycosites / Reto Ossola [and others] -- Fluorescent microsphere-based method for assay of multiple analytes in plasma / Oliver K. Bernhard [and others] -- Immuno-mass spectrometry : quantification of low-abundance proteins in biological fluids / Vathany Kulasingam [and others] -- Qualitative and quantitative analysis of glycated proteins in human plasma by glucose isotopic labeling with 13C6-reducing sugars / Feliciano Priego-Capote [and others] -- Exosome isolation for proteomic analyses and RNA profiling / Douglas D. Taylor, Wolfgang Zacharias, and Cicek Gercel-Taylor -- Extraction and proteome analysis of liver tissue interstitial fluid / Wei Sun, Ying Jiang, and Fuchu He -- Protocol for the preparation of cryoprecipitate and cryodepleted plasma / Rosemary L. Sparrow, David W. Greening, and Richard J. Simpson -- Preparation of platelet concentrates / David W. Greening, Rosemary L. Sparrow, and Richard J. Simpson -- Phosphoproteome analysis of the platelet plasma membrane / Thomas Premsler [and others] -- Statistical design and analysis of label-free LC-MS proteomic experiments : a case study of coronary artery disease / Timothy Clough [and others] -- Data management in mass spectrometry-based proteomics / Lennart Martens -- Bioinformatics challenges in the proteomic analysis of human plasma / Joseph M. Foster and Lennart Martens -- Using the human plasma peptide atlas to study human plasma proteins / Terry Farrah, Eric W. Deutsch, and Ruedi Aebersold.
  • Digital
    Committee on the Immunization Finance Dissemination Workshops, Division of Health Care Services, Institute of Medicine.
    Digital : NAPFulltext (Pt. 1)
    Digital : NAPFulltext (Pt. 2)
    Digital : NAPFulltext (Pt. 3)
    Digital : NAPFulltext (Pt. 4)
    Pt.1. Summary of the Chicago Workshop -- Pt. 2. Summary of the Austin Workshop -- Pt.3. Summary of the Los Angeles Workshop -- Pt. 4. Summary of the Washington, D.C. Workshop
  • Digital
    Michael T. Lawton.
    Digital : Thieme eNeurosurgery2011
    This book combines the instructive nature of a textbook with the visual aspects of an atlas to guide readers through the surgical principles, approaches, and techniques they need to dissect and clip cerebral aneurysms. Comprised of three concise sections, the book distills the distinguished author's vast experience into a series of easily accessible tutorials presented through clear, systematic descriptions and stunning, full-color illustrations. The first section explains the critical concepts and basic tenets of aneurysm microsurgery followed by a section on the various craniotomies and exposures necessary for successful clipping. The final section covers microsurgical anatomy, dissection strategies, and clipping techniques for each of the seven most common aneurysm types that are the focus of this book.
  • Digital
    Michael T. Lawton, MD ; illustrations by Xavier Studio: Kenneth Xavier Probst, MA, CMI.
    Digital : Thieme eNeurosurgery2014
    "The book is organized into three sections: tenets, the seven arteriovenous malformations, and selection. The tenets establish eight steps for AVM resection that comprise the phases of battle, as follows: step 1, exposure; step 2, subarachnoid dissection; step 3, defining the draining vein; step 4, defining the feeding arteries; step 5, pial dissection; step 6, parenchymal dissection;, step 7, ependymal or deep dissection; and step 8, finally resection. Critical concepts for dissection and resection are covered in the tenets section. In the section on the seven arteriovenous malformations, the anatomical battlefields for the lobes and deep regions are reviewed, 32 subtypes are described, and a resection strategy is presented for each subtype, step by step. The selection section addresses the secret to successful AVM surgery, which has nothing to do with surgical strategy or technique; rather, it is choosing your battles wisely"--Provided by publisher.
  • Digital
    John Snowdon, Graeme Halliday, Sube Banerjee.
    Digital : Cambridge2012
    "Should you intervene in the life of the 48-year-old woman whose dwelling is stuffed with accumulated rubbish and who will not let anyone help get rid of it - or the 78-year-old surrounded by putrescent food and filth - or the 'animal accumulator'? Cases of severe domestic squalor (sometimes called Diogenes Syndrome) are among the most complex and difficult faced by community agencies. Local councils, housing officers, health professionals, social services, animal welfare agencies, public guardians and of course relatives and neighbours often feel powerless and lack confidence about what to do when faced with such situations. The guidelines, recommendations and case examples in Severe Domestic Squalor will help concerned people to understand what can be done and how, by providing an understanding of the causative factors and who should take the lead in dealing with them"--Provided by publisher.
  • Digital
    A. Lerner, D. Reis, M. Soudry.
    Digital : Springer2007
    Introduction -- Primary treatment -- Definitive reconstruction -- Rehabilitation -- Treatment algorithm for missile open fractures of the limbs -- Conclusions.
  • Digital
    edited by Wynnis Tom.
    Digital : Springer2014
    Children are no less spared from severe skin diseases. This textbook is designed as a practical clinical reference that will guide practitioners in treating difficult dermatoses in children in whom topical therapy has been unsuccessful. Individual sections are devoted to inflammatory diseases, immune-mediated/autoimmune diseases, tumors and proliferative disorders, and genodermatoses. Each chapter addresses which patients represent suitable candidates for systemic or other non-topical therapy and considerations and caveats in the use of such approaches. Potential treatments are then appraised from a current evidence-based perspective, with provision of detailed but relevant information and reference tables that summarize recommendations in use and monitoring. Future directions in management are also presented.
  • Print
    Marli F. Weiner with Mazie Hough.
    Print2012
    Status: Not Checked OutLane Catalog Record
    Introduction: The Political Body -- Constructing Race -- Constructing Sex -- Placed Bodies -- Ambiguous Bodies -- The Examined Body -- The Unexamined Body -- The Diseased Body -- Conclusion: The Body Politic.
  • Digital
    Sabine Oertelt-Prigione, Vera Regitz-Zagrosek, editors.
    Digital : Springer2012
  • Digital
    Vera Regitz-Zagrosek, editor.
    Digital : Springer2013
    This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.
  • Digital
    [edited by] Alyson J. McGregor, Esther K. Choo, Bruce M. Becker.
    Digital : Cambridge2016
    "Until the last decade, clinicians and researchers assumed that the medical evaluation and treatment of both women and men were the same. This archaic and dangerous notion persisted in spite of the clear anatomic and physiologic differences between the genders. Today, we fully understand that this paradigm is false. In all specialties of medicine, practitioners and researchers are beginning to consider the influence of sex and gender and how it should inform the care of their patients. This book focuses on the issue of sex and gender in the evaluation and treatment of patients specifically in the delivery of acute medical care. It serves as a guide both to clinicians interested in the impact of sex and gender on their practice and to researchers interested in the current state of the art in the field and critical future research directions"--Provided by publisher.
  • Digital
    Sonia R. Mayoral.
    Digital2012
    Male sex is a well-established clinical risk factor for poor neurodevelopmental outcome following preterm birth. The mechanisms responsible for this sex-related difference are unknown. The damage associated with prematurity can be mimicked in rodents by prolonged exposure to sublethal, postnatal hypoxia. This chronic, sublethal hypoxia (CSH) leads to anatomical changes in mice that strongly resemble the loss of volume, decreased myelination and ventriculomegaly seen in preterm newborns. However, no sex differences have been previously explored in this rodent model. We hypothesized that sex comparisons in hypoxic mice would show sex-related differences in the brain's response to the same degree of hypoxic insult. The hippocampal formation is a brain region that is notably affected in clinical studies and we found in mice that the male hippocampus, normally larger than the female, undergoes a greater volume loss compared to females. Myelination, generally greater in males, was significantly disrupted by hypoxia in neonatal male forebrain. The numbers of oligodendrocytes were significantly reduced in male hippocampus by the end CSH treatment. Females also experienced oligodendrocyte losses, but these occurred earlier than in males and numbers recovered to normal by the end of treatment. Sex-specific oligodendrocyte losses could not be attributed to caspase-dependent cell death or to differences in proliferation. Sex hormones play a complex role in the oligodendrocyte losses, leading us to hypothesize a differential effect of estrogen and testosterone on male versus female brain. We conclude that males show greater vulnerability to myelin loss and that females show greater resilience and recovery following the initial damage. Together, these results 1) illustrate at least two mechanisms that contribute to sex differences in neurological outcome; 2) support the use of this rodent model to investigate the basis of sex-related susceptibility to brain damage, and 3) provide insights into the cellular and hormonal mechanisms that may play a role in producing sex bias in neonatal brain injury.
  • Digital
    edited by Ivanka Savic.
    Digital : ScienceDirect2010
    Section I. General Overview -- Chapter 1. Sex differences in brain anatomy / Eileen Luders, Arthur W. Toga -- Chapter 2 . Sex differences in the human brain: A developmental perspective / Tomáš Paus -- Chapter 3. Sex influences on brain and emotional memory: The burden of proof has shifted / Larry Cahill -- Chapter 4. Sexual differentiation of the human brain in relation to gender identity and sexual orientation / Ivanka Savic, Alicia Garcia-Falgueras, Dick F. Swaab -- Section II. The Mechanisms Behind Sex Dimorphism in the Brain -- Chapter 5. Genes and brain sex differences / Francisco J. Sánchez, Eric Vilain -- Chapter 6. Genetic and epigenetic underpinnings of sex differences in the brain and in neurological and psychiatric disease susceptibility / Irfan A. Qureshi, Mark F. Mehler -- Chapter 7. Gene expression in neuroendocrine cells during the critical period for sexual differentiation of the brain / Khatuna Gagnidze, Donald W. Pfaff, Jessica A. Mong -- Chapter 8. Neurosteroids: Endogenous role in the human brain and therapeutic potentials / Doodipala Samba Reddy -- Section III. Clinical Implications -- Chapter 9. Sex and gender differences in pain and analgesia / Jeffrey S. Mogil, Andrea L. Bailey -- Chapter 10. The skewed sex distribution in affective disorders: A diagnostic, social, or biological problem? / Marianne J. Legato -- Chapter 11. Empathizing, systemizing, and the extreme male brain theory of autism / Simon Baron-Cohen -- Chapter 12. Gender and the injured brain / Paco S. Herson, Patricia D. Hurn.
  • Digital
    Sabra L. Klein, Craig W. Roberts, editors.
    Digital : Springer2010
    Sex differences in susceptibility to infection : an evolutionary perspective / Marlene Zuk and Andrew M. Stoehr -- Effects of sex steroids on innate and adaptive immunity / S. Ansar Ahmed, Ebru Karpuzoglu, and Deena Khan -- Sex steroid receptors in immune cells / Susan Kovats, Esther Carreras, and Hemant Agrawal -- Sex differences in susceptibility to viral infection / Sabra L. Klein and Sally Huber -- Sex differences in innate immune responses to bacterial pathogens / Jennifer A. Rettew, Ian Marriott, and Yvette M. Huet -- Sex hormones and regulation of host responses against parasites / James Alexander ... [et al.] -- Sex differences in parasitic infections : beyond the dogma of female-biased resistance / Galileo Escobedo, Marco A. De León, and Jorge Morale-Montor -- Progesterone, pregnancy, and innate immunity / Julia Szekeres-Bartho and Beata Polgar -- Pregnancy and susceptibility to parasites / Fiona L. Henriquez, Fiona M. Menzies, and Craig W. Roberts -- Sex steroids and risk of female genital tract infection / Patti Gravitt and Khalil Ghanem -- Sex, pregnancy, and measles / Allison C. Brown and William J. Moss -- Epilogue : challenges for the future / Craig W. Roberts and Sabra L. Klein.
  • Digital
    Jon-Michael Knapp.
    Digital2010
    For my graduate work, I have chosen to investigate sex-specific patterning and function of the olfactory system in the fruit fly, Drosophila melanogaster, by addressing three questions: 1) What is the developmental genetic regulation of the sexual dimorphism in numbers of olfactory sensilla? 2) Do olfactory receptor neurons (ORNs) expressing Or47b (Or47b-ORNs) stimulate courtship in males and females? 3) Which genes are regulated by male-specific fruitless isoforms (FRUM) in olfactory and other peripheral sensory neurons? In Drosophila, terminal sexual differentiation is orchestrated by the activity of the transcription factors fruitless (fru) and doublesex (dsx). I have shown that the action of dsx alone is necessary and sufficient to specify sex-appropriate numbers of olfactory sensilla (the peripheral sensory unit). The dsx locus encodes sex-specific isoforms that differentially organize the developing antenna to specify sex-appropriate numbers of different types of olfactory sensilla. The female-specific DSX isoform promotes female-appropriate numbers of basiconic sensilla and depresses the number of trichoid sensilla on the antenna. Male-specific DSX promotes male-appropriate numbers of trichoid sensilla but appears to have little effect on determining numbers of basiconic sensilla. Inferred from the expression pattern of dsx, the DSX proteins do not show significant overlap with olfactory sensilla precursors. These data and other lines of evidence suggest that it is likely that dsx controls numbers of olfactory sensilla cell non-autonomously. One subtype of sexually dimorphic trichoid sensilla is innervated by ORNs that express the receptor Or47b and respond to a pheromone produced by males and females. I asked whether these ORNs promote male courtship and female receptivity. I have shown that Or47b-ORNs may promote courtship in males, but they appear to play no detectable role in stimulating female receptivity. Finally, in an effort to elucidate how sexual dimorphism is built into the developing olfactory system, I have collaborated with David Mellert (a former graduate student) to identify genes that are regulated by male-specific fru isoforms in peripheral sensory neurons of the olfactory and gustatory systems, as well as in mechanosensory neurons of the genitalia. We used laser capture microdissection to collect fru-expressing neurons in the antennae, prothoracic forelegs, and genitalia from fru+ and fru-null males. By comparing the whole-genome expression profiles of these samples, we were able to identify candidate targets of FRUM regulation in these tissues. For the antenna, this yielded a promising list of ~100 candidates that are in the process of being validated. Moreover, we found essentially no overlap in the candidate lists for different tissues, suggesting that FRUM regulates different genes in different tissues.
  • Digital
    volume editor, Richard Balon.
    Digital : Karger2011
    Update on diagnoses of sexual dysfunctions : controversies surrounding the proposed revisions of existing diagnostic entities and proposed new diagnoses / Balon, R. and Wise, T. -- Sexual desire and arousal disorders in women / Laan, E. and Both, S. -- Female orgasmic disorder / Rellini, A. and Clifton, J. -- Developments and trends in sex therapy / Meana, M. and Jones, S. -- The impact of cancer on sexual function / Morreale, M. -- Management of female sexual pain disorders / Boyer, S.C. ... [et al.] -- The impact of sexual trauma on sexual desire and function / McCarthy, B. and Farr, E. -- The complexity of Internet sexuality / Daneback, K. and Ross, M.W. -- Autogynephilia : an underappreciated paraphilia / Lawrence, A.A. -- Androgen deprivation treatment of sexual behavior / Houts, F.W. ... [et al.] -- Psychological and cross cultural aspects in infertility and human sexuality / Pacheco Palha, A. and Loureno, M.F.
  • Digital
    editor, R. Balon.
    Digital : Karger2008
    Introduction : new developments in the area of sexual dysfunction(s) / R. Balon -- Clinical and research evaluations of sexual dysfunctions / L.R. Derogatis -- Management of hypoactive sexual desire disorder / R.T. Segraves -- Erectile dysfunction / K. Wylie -- Recent advances in the classification, neurobiology, and treatment of premature ejaculation / M.D. Waldinger -- The impact of physical illness on sexual dysfunction / A. Clayton, S. Ramamurthy -- The impact of mental illness on sexual dysfunction / Z. Zemishlany, A. Weizman -- Psychotropics and sexual dysfunction : the evidence and treatments / L.A. Labbate -- Drugs of abuse and sexual functioning / A. Pacheco-Palha, M. Esteves -- Contribution of imaging to our understanding of sexual function and dysfunction / T.L. Woodard, M.P. Diamond.
  • Digital
    edited by John P. Mulhall.
    Digital : Springer2009
    Sexual dysfunction presents a major challenge to physicians who take on the task of treating men with prostate cancer. While curing the disease and saving a life is paramount, improving technologies and therapies offer skilled surgeons and clinical oncologists the opportunity to eradicate the disease without compromising sexual function. In Sexual Function of the Prostate Cancer Patient, John Mulhall and a panel of internationally recognized experts on prostate cancer and sexual function assess in detail the current state of prostate cancer treatment. The authors offer a broad overview of the pathophysiology and treatment of erectile dysfunction in men with prostate cancer, reviewing the latest findings regarding erection-sparing radiation therapy and sexual function outcomes after laparascopic and robotic prostatectomy. Additional chapters discuss intra-operative maneuvers to minimize post-operative erectile dysfunction and pharmacologic penile preservation and rehabilitation. Timely and authoritative, Sexual Function in the Prostate Cancer Patient is a highly readable guide to preserving post-prostate cancer sexual function that no urologist or radiation and medical oncologist should be without.
  • Digital
    Chris Sonnex.
    Digital : Springer2007
  • Digital
    Christopher Sonnex.
    Digital : Springer2015
    This fully revised and updated second edition covers the range of conditions seen in genitourinary medicine, sexual health and sexually transmitted infection clinics, making it a useful and practical guide for all health practitioners in this area. Aimed at medical practitioners, this book provides a quick reference guide to help with diagnosis and management of genital problems. In addition, it provides essential guidance on what to do next when faced with a patient presenting with a genital complaint, whether the patient can be successfully treated with a drug regimen or needs to be referred up to the sexual health and genital medicine specialist. Sexual Health and Genital Medicine in Clinical Practice, Second Edition is of particular interest to residents on their rotations through this field of medicine, doctors in training, specialist nurses, and primary care practitioners.
  • Digital
    Klaus M. Beier, Kurt K. Loewit.
    Digital : Springer2013
    A short reader for a holistic approach on human sexuality and its disorders -- Interdisciplinary references in sexual medicine -- Basic understanding of human sexuality -- The spectrum of sexual disorders -- Principles of diagnostics in sexual medicine -- Principles of therapy in sexual medicine -- New challenges for sexual medicine.
  • Digital
    Sana Loue.
    Digital : Springer2006
    Diverse monogamies -- Multi-bonding: polygamy, polygyny, polyamory -- Child "partnering": incest, pedophilia, and child marriage -- Commercial partnering: sex work, trafficking, and pornography -- Object relations: fetish and related behaviors.
  • Digital
    Sana Loue, editor.
    Digital : Springer2009
  • Digital
    Jennifer Hillman.
    Digital : Springer2012
  • Print
    edited by Earl E. Shelp.
    Status: Not Checked OutLane Catalog Record
    v. 1. Conceptual roots.--v.2 Ethical viewpoints in transition.
  • Digital
    Alexander McMillan.
    Digital : Springer2009
  • Print
    editors, King K. Holmes ... [et al.].
    Print2008
    Status: Not Checked OutLane Catalog Record
  • Digital
    Neil S. Skolnik, Amy Lynn Clouse, Jo Ann Woodward, editors.
    Digital : Springer2013
    Sexually Transmitted Diseases: A Practical Guide for Primary Care, Second Edition, covers the diagnosis and treatment of STDs and other information critical to patient care, and reflects the last five years of significant changes in information about STDs. Updated to reflect the 2010 Centers for Disease Control Guidelines on the Treatment of STDs, this book also contains new information about: -the epidemiology of herpes virus infections -expedited partner therapy -changes in recommendations for HPV vaccination for men -changes in resistance patterns for antimicrobial therapy for gonorrhea and chlamydia -treatment recommendations for genital warts In order to better meet clinician needs, the book has been streamlined to quickly convey critical, evidence-based information. Whether seeking information about particular conditions (including HPV, herpes, syphilis, trichomaniasis, HIV, and others) or related patient issues (such as STD exposure evaluation and evaluation of sexual assault), Sexually Transmitted Diseases, Second Edition, contains all the knowledge clinicians need in a friendly, to-the-point format.
  • Digital
    prepared by Kimberly A. Workowski, Stuart M. Berman.
    Digital : CDC2006
    "These guidelines for the treatment of persons who have sexually transmitted diseases (STDs) were developed by CDC after consultation with a group of professionals knowledgeable in the field of STDs who met in Atlanta, Georgia, during April 19-21, 2005. The information in this report updates the Sexually Transmitted Diseases Treatment Guidelines, 2002 (MMWR 2002;51[No. RR-6]). Included in these updated guidelines are an expanded diagnostic evaluation for cervicitis and trichomoniasis; new antimicrobial recommendations for trichomoniasis; additional data on the clinical efficacy of azithromycin for chlamydial infections in pregnancy; discussion of the role of Mycoplasma genitalium and trichomoniasis in urethritis/cervicitis and treatment-related implications; emergence of lymphogranuloma venereum protocolitis among men who have sex with men (MSM); expanded discussion of the criteria for spinal fluid examination to evaluate for neurosyphilis; the emergence of azithromycin- resistant Treponema pallidum; increasing prevalence of quinolone-resistant Neisseria gonorrhoeae in MSM; revised discussion concerning the sexual transmission of hepatitis C; postexposure prophylaxis after sexual assault; and an expanded discussion of STD prevention approaches." - p. 1
  • Digital
    Gerd Gross, Stephen K. Tyring (editors)
    Digital : Springer2011
    Springer e-books..
  • Digital
    von Sanitätsrat Dr. Magnus Hirschfeld.
    Digital : Google BooksFulltext (v.1 1918)
    Digital : Google BooksFulltext (v.2 1918)
    pt. 1. Geschlechtliche Entwicklungsstörungen mit besonderer Berücksichtigung der Onanie -- pt. 2. Sexuelle Zwischenstufen das männliche Weib und der weibliche Mann -- pt. 3. Störungen im Sexualstoffwechsel mit besonderer Berücksichtigung der Impotenz.
  • Print
    [edited by] Charles J. Yeo.
    Status: Not Checked OutLane Catalog Record
  • Digital
    [edited by] Charles J. Yeo.
    Digital : ClinicalKeyv.1-2, 2013
    Comprehensive and complete, this book delivers the definitive, clinically oriented, cutting-edge guidance you need to achieve optimal outcomes managing the entire spectrum of gastrointestinal disorders. Make effective use of the latest endoscopic, robotic, and minimally invasive procedures as well as medical therapies with unbeatable advice from a "who's who" of international authorities! Shorten patient recovery time and lessen surgical risks using the latest minimally invasive and robotic techniques, including natural orifice translumenal endoscopic surgery, endoscopic plication for gastrointestinal reflux disease, and much more. Achieve total patient management by applying the newest pharmacologic treatments, including new drugs to be used alongside surgical therapies. Personalize treatments for IBD, cancer, and other inherited disorders with therapies based on genomics and proteomics. Take full advantage of the most recent advances in immunosuppression for transplant patients. Effectively treat diseases of the GI Tract with a comprehensive overview of both the basic science and the clinical information associated with surgery in this area.
  • Digital
    edited by Raymond Schulz ... [et al.] ; editor-in-chief, Antonio A.F. Salles.
    Digital : Springer2011
    Novalis® Shaped Beam Radiosurgery has set new standards by delivering highly precise radiation treatments to tumors anywhere in the body through the use of a proprietary multileaf collimator. By shaping the radiation beam to the exact contours of the tumor or lesion, Novalis permits maximum dose delivery to the entire tumor while protecting healthy tissue; this makes it eminently suitable for the treatment of irregularly shaped tumors. Novalis features 360° gantry rotation, stereoscopic kV X-ray imaging, and 6D robotic patient positioning. Dose delivery is typically achieved through fixed conformal beams, dynamic conformal arcs, and IMRT, and most brain treatments do not require an invasive head frame. This book provides a complete guide to radiosurgery treatments with Novalis. After a thorough discussion of the clinical and technical basis for Shaped Beam Radiosurgery, current clinical applications are considered in detail, including brain, body, skull base, and spinal tumors as well as arteriovenous malformations. Careful consideration is also given to future developments and applications, including new technologies that promise to offer even more accurate treatments. This state-of-the-art book will appeal to a wide audience of physicians and their multidisciplinary clinical and technical collaborators.
  • Digital
    [Alexandra Ernst].
    Digital2013
    Shared decision making has the potential to help achieve better health and better care at a lower cost by giving health care consumers the tools they need to partner with their health care providers to make decisions based on medical evidence and personal preferences. Encouraging shared decision making is especially important because Americans are paying more and more for their health care, often with little say in the type of care they receive. Patients rarely know or understand all of their options. As a result, they often receive care that is based more on their provider's habits than their own preferences. Patients who are more involved in their health care are happier with their health care decisions and are more likely to follow treatment plans, which can lead to better health outcomes. It is important for advocates to be involved in the development of shared decision-making programs to ensure that they improve health and quality of care for all consumers. This brief provides an overview of shared decision making and answers key questions about how it can improve patient care, how to design a good shared decision-making program, and how shared decision making fits into a more patient-centered health care system.
  • Digital
    Seth Bates and Tony Smith.
    Digital : Springer2007
  • Print
    Dux Raymond Sy.
    Print2009
  • Digital
    Steve Olson and Autumn S. Downey, rapporteurs ; Forum on Drug Discovery, Development, and Translation, Forum on Neuroscience and Nervous System Disorders, National Cancer Policy Forum, Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Board on Health Care Services, Institute of Medicine of the National Academies.
    Digital2013
    Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health all possess large quantities of clinical research data. If these data were shared more widely within and across sectors, the resulting research advances derived from data pooling and analysis could improve public health, enhance patient safety, and spur drug development. Data sharing can also increase public trust in clinical trials and conclusions derived from them by lending transparency to the clinical research process. Much of this information, however, is never shared. Retention of clinical research data by investigators and within organizations may represent lost opportunities in biomedical research. Despite the potential benefits that could be accrued from pooling and analysis of shared data, barriers to data sharing faced by researchers in industry include concerns about data mining, erroneous secondary analyses of data, and unwarranted litigation, as well as a desire to protect confidential commercial information. Academic partners face significant cultural barriers to sharing data and participating in longer term collaborative efforts that stem from a desire to protect intellectual autonomy and a career advancement system built on priority of publication and citation requirements. Some barriers, like the need to protect patient privacy, present challenges for both sectors. Looking ahead, there are also a number of technical challenges to be faced in analyzing potentially large and heterogeneous datasets. This public workshop focused on strategies to facilitate sharing of clinical research data in order to advance scientific knowledge and public health. While the workshop focused on sharing of data from preplanned interventional studies of human subjects, models and projects involving sharing of other clinical data types were considered to the extent that they provided lessons learned and best practices. The workshop objectives were to examine the benefits of sharing of clinical research data from all sectors and among these sectors, including, for example: benefits to the research and development enterprise and benefits to the analysis of safety and efficacy. Sharing Clinical Research Data: Workshop Summary identifies barriers and challenges to sharing clinical research data, explores strategies to address these barriers and challenges, including identifying priority actions and "low-hanging fruit" opportunities, and discusses strategies for using these potentially large datasets to facilitate scientific and public health advances.
  • Digital
    Committee on Strategies for Responsible Sharing of Clinical Trial Data, Board on Health Sciences Policy, Institute of Medicine.
    Digital : NAPFulltext
    Digital : NAPRelated material
    Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research--from funders, to researchers, to journals, to physicians, and ultimately, to patients.
  • Print
    Gerald M. Oppenheimer, Ronald Bayer.
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    Carolyn J. Heckman, Sharon L. Manne, editors.
    Digital : Springer2012
    1. Introduction -- 2. History and culture of tanning in the United States -- 3. Prevalence and correlates of indoor tanning -- 4. Motivation for indoor tanning: theoretical models -- 5. How ultraviolet radiation tans skin -- 6. Skin cancer and other health effects of indoor tanning -- 7. Tanning dependence: is tanning an addiction? -- 8. Selected indoor tanning myths and controversies -- 9. A systematic review of intervention efforts to reduce indoor tanning -- 10. Indoor tanning regulation, enforcement, taxation, and policy -- 11. Sunless tanning -- 12. International perspectives on indoor tanning -- 13. Indoor tanning: past, present, and future -- Index.
  • Digital
    Tracey Loughran.
    Digital : Cambridge2017
    Shell-Shock and Medical Culture in First World War Britain' is a thought-provoking reassessment of medical responses to war-related psychological breakdown in the early twentieth century. Dr Loughran places shell-shock within the historical context of British psychological medicine to examine the intellectual resources doctors drew on as they struggled to make sense of nervous collapse. She reveals how medical approaches to shell-shock were formulated within an evolutionary framework which viewed mental breakdown as regression to a level characteristic of earlier stages of individual or racial development, but also ultimately resulted in greater understanding and acceptance of psychoanalytic approaches to human mind and behaviour. Through its demonstration of the crucial importance of concepts of mind-body relations, gender, willpower and instinct to the diagnosis of shell-shock, this book locates the disorder within a series of debates on human identity dating back to the Darwinian revolution and extending far beyond the medical sphere.
  • Digital
    editors, Kenneth J. Ryan, C. George Ray.
    Digital : AccessMedicine2010
    The nature of infection / Kenneth J. Ryan and C. George Ray -- Pathogenic viruses / Nafees Ahmad, C. George Ray, and W. Lawrence Drew -- Pathogenic bacteria / Kenneth J. Ryan and W. Lawrence Drew -- Pathogenic fungi / Kenneth J. Ryan -- Pathogenic parasites / C. George Ray and James J. Plorde -- Clinical aspects of infection / C. George Ray, Kenneth J. Ryan, and W. Lawrence Drew.
  • Digital
    editors, Kenneth J. Ryan, C. George Ray.
    Digital : AccessMedicine2014
    Infection -- Infection: basic concepts -- Immune response to infection -- Sterilization, disinfection, and infection control -- Principles of laboratory diagnosis of infectious diseases -- Emergence and global spread of infection -- Pathogenic viruses -- Viruses: basic concepts -- Pathogenesis of viral infection -- Antiviral agents and resistance -- Influenza, parainfluenza, respiratory syncytial virus, adenovirus, and other respiratory viruses -- Viruses of mumps, measles, rubella, and other childhood exanthems -- Poxviruses -- Enteroviruses -- Hepatitis viruses -- Herpesviruses -- Viruses of diarrhea -- Arthropod-borne and other zoonotic viruses -- Rabies -- Retroviruses: human T-lymphotropic virus, human immunodeficiency virus, and acquired immunodeficiency syndrome -- Papilloma and polyoma viruses -- Persistent viral infections of the central nervous system -- Pathogenic bacteria -- Bacteria: basic concepts -- Pathogenesis of bacterial infections -- Antibacterial agents and resistance -- Staphylococci -- Streptococci and enterococci -- Corynebacterium, Listeria, and Bacillus -- Mycobacteria -- Actinomyces and Nocardia -- Clostridium, Peptostreptococcus, Bacteroides, and other anaerobes -- Neisseria -- Haemophilus and Bordetella -- Vibrio, Campylobacter, and Helicobacter -- Enterobacteriaceae -- Legionella and Coxiella -- Pseudomonas and other opportunistic gram-negative bacilli -- Plague and other bacterial zoonotic diseases -- Spirochetes -- Mycoplasma -- Chlamydia -- Rickettsia, Ehrlichia, Anaplasma, and Bartonella -- Dental and periodontal infections -- Pathogenic Fungi -- Fungi: basic concepts -- Pathogenesis and diagnosis of fungal infection -- Antifungal agents and resistance -- Dermatophytes, Sporothrix, and other superficial and subcutaneous fungi -- Candida, Aspergillus, Pneumocystis, and other opportunistic fungi -- Cryptococcus, Histoplasma, Coccidioides, and other systemic fungal pathogens -- Pathogenic parasites -- Parasites: basic concepts -- Pathogenesis and diagnosis of parasitic infection -- Antiparasitic agents and resistance -- Apicomplexa and microsporidia -- Sarcomastigophora: the amebas -- Sarcomastigophora: the flagellates -- Intestinal nematodes -- Tissue nematodes -- Cestodes -- Trematodes -- Glossary -- Infectious diseases: syndromes and etiologies.
  • Digital
    senior author, R. Rand Allingham ; associate authors, Karim F. Damji ... [et al.].
    Digital : Ovid2011
  • Digital
    edited by R. Ferrari.
    Digital : HighWire2001
    Print2001
  • Digital
    Hiroshi Shimizu.
    Digital : Wiley2017
    Structure and function of the skin -- Histopathology of the skin -- Dermoscopy -- Description of skin lesions -- Diagnosis of skin diseases -- Treatment of skin diseases -- Eczema and dermatitis -- Urticaria, prurigo and pruritus -- Erythema and erythroderma -- Drug-induced skin reactions (DISRs) and graft-versus-host disease (GVHD) -- Vasculitis, purpura and other vascular diseases -- Collagen diseases -- Physicochemical injury and photosensitive diseases -- Blistering and pustular diseases -- Disorders of keratinization -- Disorders of skin color -- Metabolic disorders -- Disorders of the dermis and subcutaneous fat -- Disorders of the skin appendages -- Nevi and neurocutaneous syndromes.
  • Digital
    Levinson, Gershon; Shnider, Sol M.; Suresh, Maya.
    Digital : Ovid2013
  • Digital
    Thomas M. Scalea, editor.
    Digital : Springer2015
    Neck -- The Chest -- Emergency Department Thoracotomy -- Indications and Techniques for Trauma Laparotomy -- Indication and Techniques for Vascular Exploration -- Intubation, Cricothyrotomy, Tube Thoracostomy, Diagnostic Peritoneal Lavage, and Local Wound Exploration -- Ultrasound Physics for Point-of-Care Imaging: Performing the Various Exams with Technical Tips -- Trachea, Bronchus, and Esophagus -- The Lungs -- Cardiac Injury -- Liver Injuries -- The Spleen -- Pancreas and Duodenum -- Stomach, Small Bowel, and Colon -- Trauma of the Kidney, Ureter, Bladder -- Traumatic Injuries and Common Surgical Emergencies of the External Genitalia and Urethra.- Cervical Vascular Injuries -- Thoracic Vascular Injuries -- Endovascular Therapy in Trauma -- Timing of Fracture Fixation -- Treatment of Pelvic Fractures.
  • Digital
    Marco Piccolino, Marco Bresadola ; translated by Nicholas Wade.
    Digital : OSO2013
    Foreword -- Authors' preface to the Italian edition -- Authors' preface to the English edition -- Acknowledgments -- Bibliographical note -- 1. Galvani, Volta and the forgotten electrophysiology -- 2. "Truth and usefulness": medicine and natural philosophy in the eighteenth century -- 3. Animal spirits, vital forces, and electricity: nervous conduction and muscular motion in the eighteenth century -- 4. Artificial electricity, the spark, and the nervous fluid: Galvani's early research on muscular motion -- 5. A "fortunate" discovery: Galvani's theory of animal electricity -- 6. The controversy between Galvani and Volta over animal electricity: the first stage -- 7. The controversy between Galvani and Volta over animal electricity: the second stage -- 8. The electrophysiological work of Alessandro Volta -- 9. From Galvani to Hodgkin and beyond: the central problem of electrophysiology in the last two centuries -- 10. Neuromuscular excitability: the modern explanation -- 11. Concluding remarks.
  • Digital
    Douglas W Arthur, Frank A. Vicini, David E. Wazer, Atif J. Khan, editors.
    Digital : Springer2016
    PART I: Accelerated Breast Irradiation: History, Rationale, and Controversies -- Pathologic Anatomy of Early-Stage Breast Cancer: Defining the Target -- The Radiobiology of Accelerated Breast Irradiation -- Quality Assurance and Radiation Safety/Medical Events -- Surgical Considerations in Partial Breast Irradiation -- Impact of Oncoplastic Surgery on adjuvant XRT -- Comparison of true cost between modalities in a changing health care system -- PART II: Hypofractionated WBI: Patient Selection -- Physics of HWBI -- Treatment History -- PART III: Accelerated Partial Breast Irradiation: Patient Selection -- Physics of Accelerated Partial Breast Irradiation -- Interstitial brachytherapy -- Intracavitary brachytherapy -- 3D-Conformal external beam radiotherapy -- PART IV: Intra-operative Radiation Therapy: Patient Selection -- Physics of IORT -- 50 kV Photons: Targeted Intraoperative Radiotherapy (TARGIT) -- Intraoperative Technique with Electrons -- PART V: Emerging treatment approaches: Extreme hypofractionation (brachytherapy, Gammapod, UK FAST WBI) -- APBI for breast augmentations -- Accuboost -- APBI for in-breast recurrence following WBI -- Preoperative partial breast -- Locoregional Hypofractionation -- PART VI: Hypofractionation for metastatic disease: Stereotactic treatment for Oligometastatic disease -- Hypofractionaton for palliation.
  • Digital
    edited by D.A. Christie and E.M. Tansey.
    Digital : Wellcome Trust2005
  • Print
    Jan A. Pechenik.
    Print2007
    Status: Not Checked OutLane Catalog Record
  • Digital
    W. Frank Peacock, editor.
    Digital : Springer2012
    Part 1. Administrative and Regulatory Issues / Society of Chest Pain Centers' Heart Failure Accreditation / Kay Styer Holmes and Arlene Mavko -- The Economics and Reimbursement of Congestive Heart Failure / Sandra Sieck -- Regulatory Requirements in Acute Heart Failure / Nancy M. Albert -- Quality and Operational Metrics in Heart Failure / Phillip D. Levy and Matthew A. Wheatley -- Interaction of Performance Measurements, Staffing, and Facility Requirements for the Heart Failure Observation Unit / Valorie Sweigart and Karen Krechmery -- Part 2. Pathophysiology and Demographics / Heart Failure: Epidemiology and Demographics / Karina M. Soto-Ruiz -- Pathophysiology of Acute Decompensated Heart Failure / Ezra A. Amsterdam, Kathleen L. Tong and Richard Summers -- Part 3. Emergency Medical Services and Emergency Department Assessment and Treatment / The Out-of-Hospital Management of Acute Heart Failure / Marvin A. Wayne, Vincent N. Mosesso and A. Keith Wesley -- Dyspnea Assessment and Airway Management in Acute Heart Failure Syndromes Patients / Masood Zaman and Peter S. Pang -- Volume Assessment in the Emergency Department / Anna Marie Chang and Judd E. Hollander -- Diagnostic and Prognostic Biomarkers in Emergency Department Heart Failure / Yang Xue, Arrash Fard, Navaid Iqbal and Alan Maisel -- Emergency Department Therapy of Acute Heart Failure / Phillip D. Levy -- Part 4. Observation Unit Entry Treatment and Disposition / Observation Unit Admission Inclusion and Exclusion Criteria / Gregory J. Fermann and Sean P. Collins -- Acute Heart Failure in Observation Unit Treatment Protocols / J. Douglas Kirk and Michael Clarke -- Education Elements in the Observation Unit for Heart Failure Patients / Robin J. Trupp -- Emergency Department and Observation Unit Discharge Criteria / Rachel Rockford and Deborah B. Diercks -- Effective Discharge Planning / Ginger Conway -- Outpatient Medication Titration in Acute Heart Failure / Khadijah Breathett and L. Kristin Newby -- Part 5. Complications and Future Research/ Drugs to Avoid in Acute Heart Failure: Contraindicated Medications and Interactions / James McCord -- Implications of Atrial Fibrillation in Heart Failure Management / Chad E. Darling and Richard V. Aghababian -- Implantable Cardiac Devices / Brian Hiestand and William Abraham -- Heart Failure and Kidney Disease: Management in the Short-Stay Unit / Shahriar Dadkhah and Korosh Sharain -- Heart Failure Research in the Emergency Department and Observation Unit / Candace McNaughton, Patricia Fick and Alan Storrow -- Appendix: Shared Practice Examples / Kay Styer Holmes.
  • Digital
    William Franklin Peacock, Christopher P. Cannon, editors.
    Digital : Springer2009
    Epidemiology and demography of coronary artery disease / S. Dadkhah and K. Sharain -- Financial impact of acute coronary syndromes: The need for new care delivery models / S. Sieck -- Why have a chest pain unit? / A. Annathurai and M.A. Ross -- Pathophysiology and definition of the acute coronary syndromes / E.A. Amsterdam, D. Diercks and J.D. Kirk -- Emergency department presentation / J.A. Holmes and S. Collins -- Risk stratification: History, physical, and EKG / A.B. Storrow, I. McClure and E. Harbison -- Cardiac markers: A chest pain center focus / R.H. Christenson -- Risk stratification using scoring systems / J.E. Hollander and A.M. Chang -- Emergency department disposition of patients presenting with chest pain / K. Owen and D.B. Diercks -- Short-stay unit requirements / L. Graff and iv -- Medical therapy in patients managed in a chest pain observation unit / J. McCord -- Provocative testing / J.D. Kirk, M.C. Kontos and E.A. Amsterdam -- Use of multislice CT and MRI for the evaluation of patients with chest pain / B. O'Neil, M.J. Gallagher and G.L. Raff -- Disposition from the short stay unit / C.A. Ghaemmaghami and W.J. Brady -- Examples of patient discharge instructions, ACS rule out protocols, and order sheets / K.S. Holmes.
  • Digital
    W.E. Thomas, N. Senninger (eds.).
    Digital : Springer2008
  • Digital
    edited by Daniel Martins-de-Souza, Laboratory of Neuroprotemics, Department of Biochemistry, Institute of Biology, State University of the Campinas (UNICAMP), Campinas, Brazil, Max Planck Institute of Psychiatry, Munich, Germany, Research Group of Proteomics, Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University of Munich, Munich, Germany, Laboratory of Neurosciences (LIM-27), Institute of Psychiatry, University of Sao Paulo, Sao Paulo, Brazil.
    Digital : Springer Protocols2014
    Survey of shotgun proteomics / Fabio Cesar Sousa Nogueira and Gilberto B. Domont -- LC-MALDI-TOF/TOF for shotgun proteomics / Patricia Fernández-Puente ... [et al.] -- Fully automatable multidimensional reversed-phase liquid chromatography with online tandem mass spectrometry / Maggie P.Y. Lam ... [et al.] -- GeLC-MS/MS analysis of complex protein mixtures / Monika Dzieciatkowska, Ryan Hill, and Kirk C. Hansen -- IPG strip-based peptide fractionation for shotgun proteomics / Murat Eravci, Christian Sommer, and Matthias Selbach -- SILAC yeast : from labeling to comprehensive Proteome Quantification / Lyris M. F. de Godoy -- Analysis of proteome dynamics in mice by isotopic labeling / John C. Price and Sina Ghaemmaghami -- Stable isotope labeling in mammals (SILAM) / Daniel B. McClatchy and John R. Yates III -- Analysis of individual protein turnover in live animals on a proteome-wide scale / Stefan Reckow and Christian Webhofer -- Determining protein subcellular localization in mammalian cell culture with biochemical fractionation and iTRAQ 8-plex quantification / Andy Christoforou, Alfonso Martinez Arias, and Kathryn S. Lilley -- Brain quantitative proteomics combining GeLC-MS and isotope-coded protein labeling (ICPL) / Giuseppina Maccarrone, Maria Lebar, and Daniel Martins-de-Souza -- Employing TMT quantification in a shotgun-MS platform / Darragh P. O'Brien and John F. Timms -- Employing TMT quantification in shotgun-MS proteomic analysis : a focus on skeletal muscle / Bruno Menezes de Oliveira -- Spectral counting label-free proteomics / Liisa Arike and Lauri Peil -- Quantification of proteins by label-free LC-MSE / Alon Savidor and Yishai Levin -- Bioinformatics for proteomics : opportunities at the interface between the scientists, their experiments, and the community / Marc Vaudel ... [et al.] -- Identification of DNA damage checkpoint-dependent protein interactions in Saccharomyces cerevisiae using quantitative mass spectrometry / Francisco M. Bastos de Oliveira and Marcus B. Smolka -- Application of shotgun proteomics for discovery-driven protein-protein interaction / Livia Goto-Silva ... [et al.] -- Mapping protein complexes using covalently linked antibodies and isobaric mass tags / Antje Dittmann ... [et al.] -- Biomarker verification using selected reaction monitoring and shotgun proteomics / Angel Mauricio Castro-Gamero, Clarice Izumi, and José César Rosa -- Use of universal stable isotope labeling by amino acids in cell culture (SILAC)-based selected reaction monitoring (SRM) approach for verification of breast cancer-related protein markers / Ning Qing Liu ... [et al.] -- Secretome analysis by high-throughput proteomics and multiple reaction monitoring (MRM) / Vitor M. Faça ... [et al.] -- Preparation of heteroelement-incorporated and stable isotope-labeled protein standards for quantitative proteomics / Anna Konopka ... [et al.] -- One-source peptide/phosphopeptide ratio standards for accurate and site-specific determination of the degree of phosphorylation / Martin E. Boehm, Bettina Hahn, and Wolf D. Lehmann -- Quantitative glycoproteomics for N-glycoproteome profiling / Sheng Pan -- Practical recipe to survey phosphoproteomes / William C. Edelman ... [et al.] -- Quantitation of the phosphoproteome using the library-assisted eXtracted ion chromatogram (LAXIC) strategy / Justine V. Arrington, Liang Xue, and W. Andy Tao -- Fast, efficient, and quality-controlled phosphopeptide enrichment from minute sample amounts using titanium dioxide / Clarissa Dickhut, Sonja Radau, and René P. Zahedi -- Quantifying small molecule-induced changes in cellular protein expression and posttranslational modifications using isobaric mass tags / Isabelle Becher, Maria Fälth Savitski, and Marcus Bantscheff -- Analysis of protein structure by cross-linking combined with mass spectrometry / Evgeniy V. Petrotchenko ... [et al.] -- Top-down proteomics by means of orbitrap mass spectrometry / Kai Scheffler.
  • Print
    editors, Charles A. Rockwood Jr., Michael A. Wirth, Frederick A. Matsen, III, Steven B. Lippitt ; associate editors, Edward V. Fehringer, John W. Sperling.
    Status: Not Checked OutLane Catalog Record
  • Digital
    [edited by] Donald H. Lee, Robert J. Neviaser.
    Digital : ClinicalKey2011
    Acromioplasty -- Rotator Cuff Repair: Open Technique for Partial-Thickness or Small or Medium Full-Thickness Tears -- Rotator Cuff Repair: Arthroscopic Technique for Partial-Thickness or Small or Medium Full-Thickness Tears -- Open Repair of Rotator Cuff Tears -- Arthroscopic Repair of Massive Rotator Cuff Tears -- Operative Fixation of Symptomatic Os Acromiale -- Humeral Head Resurfacing Arthroplasty -- Humeral Hemiarthroplasty with Biologic Glenoid Resurfacing -- Total Shoulder Arthroplasty -- Rotator Cuff Tear Arthroplasty: Open Surgical Treatment -- Open Unconstrained Revision Shoulder Arthroplasty -- Arthroscopic Treatment of Traumatic Anterior Instability of the Shoulder -- Open Treatment of Anterior-Inferior Multidirectional Instability of the Shoulder -- Arthroscopic Treatment of Anterior-Inferior Multidirectional Instability of the Shoulder -- Anterior Glenohumeral Instability Associated with Glenoid or Humeral Bone Deficiency: The Latarjet Procedure -- Open Treatment of Posterior-Inferior Multidirectional Shoulder Instability -- Arthroscopic Treatment of Posterior-Inferior Multidirectional Instability of the Shoulder -- Open Bankart Procedure for Recurrent Anterior Shoulder Dislocation -- Mini-Open Biceps Tenodesis -- Arthroscopic Biceps Tenodesis -- SLAP Lesion: Arthroscopic Reconstruction of the Labrum and Biceps Anchor -- Treatment of the Unstable Shoulder with Humeral Head Bone Loss -- Open Distal Clavicle Excision -- Arthroscopic Distal Clavicle Resection -- Open Treatment of Acute and Chronic Acromioclavicular Dislocations -- Sternoclavicular Joint Reconstruction Using Semitendinosus Graft -- Open Reduction and Internal Fixation of Acute Midshaft Clavicular Fractures -- Intramedullary Fixation of Clavicle Fractures -- Operative Treatment of Two-Part Proximal Humerus Fractures -- Open Reduction and Internal Fixation of Three- and Four-Part Proximal Humerus Fractures -- Percutaneous Fixation of Proximal Humerus Fractures -- Hemiarthroplasty for Proximal Humerus Fracture -- Surgical Treatment of Scapular Fractures -- Arthrodesis of the Shoulder -- Open and Arthroscopic Suprascapular Nerve Decompression -- Scapular Surgery I: Eden-Lange Transfer for Trapezius Muscle Palsy -- Scapular Surgery II: Pectoralis Major Transfer for Serratus Anterior Palsy -- Scapular Surgery III: Rhomboid/Latissimus Dorsi Transfer for Serratus Anterior Palsy -- Adhesive Capsulitis -- Arthroscopic Treatment of Calcific Tendinitis in the Shoulder -- Surgical Approaches for Open Treatment of the Elbow I: Posterior Approach -- Arthroscopy of the Elbow: Setup and Portals -- Elbow Arthritis and Stiffness: Open Treatment -- Elbow Arthritis and Stiffness: Arthroscopic Treatment -- Radial Head Fractures: Radial Head Replacement -- Total Elbow Arthroplasty: Discovery Minimally Constrained Linked System -- Total Elbow Arthroplasty for the Treatment of Complex Distal Humerus Fractures -- Hemiarthroplasty of the Distal Humerus -- Radiocapitellar Replacement -- Revision Total Elbow Arthroplasty -- Medial Epicondylitis: Open Treatment -- Lateral Epicondylitis: Arthroscopic and Open Treatment -- Repair of Distal Biceps Tendon Ruptures -- Repair and Reconstruction of the Ruptured Triceps -- Endoscopic Cubital Tunnel Release -- Submuscular Ulnar Nerve Transposition -- Surgical Decompression for Radial Tunnel Syndrome -- Distal Humerus Fractures, Including Isolated Distal Lateral Column and Capitellar Fractures -- Radial Head Fractures: Open Reduction and Internal Fixation -- Open Treatment of Complex Traumatic Elbow Instability -- Surgical Reconstruction of Longitudinal Radioulnar Dissociation (Essex-Lopresti Injury) -- Ulnar Collateral Ligament Reconstruction Using the Modified Jobe Technique -- Lateral Ulnar Collateral Ligament Reconstruction -- Soft Tissue Coverage I: Radial Forearm Flap -- Soft Tissue Coverage II: Latissimus Dorsi Flap -- Soft Tissue Coverage III: Posterior Interosseous Flap -- Soft Tissue Coverage IV: Brachioradialis Muscle Flap -- Soft Tissue Coverage V: Reverse Lateral Arm Flap -- Operative Treatment of Olecranon Bursitis -- Elbow Arthroscopic Débridement for Osteochondritis Dissecans.
  • Digital
    Gary M. Gartsman, T. Bradley Edwards.
    Digital : ClinicalKey2008
    Here is a technique textbook of shoulder arthroplasty detailing how to handle all relevant aspects of shoulder replacement surgery. Distinguished shoulder surgeons Gary M. Gartsman and T. Bradley Edwards provide step-by-step details for each category of shoulder arthroplasty, covering indications and contraindications, pre-operative planning and imaging, results and complications, and more. Copious color intraoperative photographs and illustrations and a bonus DVD of 17 surgical video clips of procedures discussed in the text complement the text.
  • Digital
    Gary M. Gartsman.
    Digital : ClinicalKey2009
    The new edition of this step-by-step guide covers the entire spectrum of operative shoulder arthroscopy from initial operation room set-up through advanced reconstructive procedures. View all-new illustrations and apply the latest treatment options for Bankart repair, SLAP repair, and repair of a full range of rotator cuff lesions, along with strategies for stiff shoulders and osteoarthritis. The included DVD narrated by Dr. Gartsman demonstrates exactly how to complete both simple and complex operations in over three hours of video clips. Whether you are a novice or an experienced shoulder surgeon, improve your technique with the expertise of Dr. Gartsman. Provides detailed step-by-step descriptions of Dr. Gartsman's approach-including variations and complications-so that you can reproduce his results. Includes a DVD with video clips of procedures demonstrating Dr. Gartsman's surgical techniques. Presents the most current scientific data on the treatment outcomes of specific.
  • Digital
    Olivier Courage ; with Forewords by Stephen S. Burkhart, Philippe Hardy.
    Digital : Springer2015
    Prefaces -- Introduction -- Chapter 1 Being in the right conditions -- 1.1 Avoiding steam -- 1.2 Properly entering the shoulder -- 1.3 Avoiding blood -- Chapter 2 Being properly installed -- 2.1 Installing the patient -- 2.2 The surgeon's ergonomy -- Chapter 3 Basic essentials -- 3.1 Stable image -- 3.2 Straight image -- 3.3 Finding your instruments -- Chapter 4 Exploring the shoulder -- 4.1 The glenohumeral -- 4.2 The subacromial space -- Chapter 5 Tips for the key surgeries -- 5.1 Before the surgical arthroscopy -- 5.2 The rotator cuff -- 5.3 The subscapularis -- 5.4 The biceps -- 5.5 Instability and the arthroscopic Bankart -- Chapter 6 Less frequent surgeries -- 6.1 The acromioclavicular -- 6.2 The subscapularis nerve -- Chapter 7 How to evolve your techniques -- 7.1 Analyze your mistakes, travel and create -- Conclusion.
  • Digital
    Giuseppe Milano, Andrea Grasso, editors.
    Digital : Springer2014
    This comprehensive and stunningly illustrated textbook covers the entire spectrum of shoulder disease and arthroscopic techniques. It reviews the anatomy and the biomechanics of the shoulder, basic arthroscopic procedures, advanced reconstructive surgeries, and an overview on shoulder pathologies with a special focus on surgical approach. Shoulder Arthroscopy: Principles and Practice is a highly organized reference with all chapters following a standardized format: from detailed descriptions regarding epidemiology, pathophysiology, clinical findings, imaging, indication for treatment up to a step-by-step description of current surgical techniques, including tips and tricks on how to avoid the most common mistakes and complications. There is also an entire section dedicated to the evaluation of outcome measurements. The tips and techniques presented in this book are based on the Editor and his Contributors' individual experience. The book guides the orthopaedic resident and fellow who wants to focus on shoulder diseases, but it also represents a landmark reference for expert surgeons already involved in shoulder surgery.
  • Digital
    edited by Guillermo Arce, Klaus Bak, Kevin P Shea, Felix Savoie III, William Benjamin Kibler, Eiji Itoi, Augustus D. Mazzocca, Knut Beitzel, Emilio Calvo, Benno Ejnisman.
    Digital : Springer2013
    The ISAKOS Upper Extremity Committee (UEC) meets on a biannual basis for Closed Consensus Meetings. Each summit, a worldwide expert panel of surgeons and researchers convene for an in-depth discussion about a controversial topic. The purpose of this endeavor is to combine expertise and reach international consensus for the most appropriate management of various shoulder disorders. This booklet constitutes an integral part of the agreement encountered during these meetings. Section A provides a comprehensive review of the currently available Classifications and Outcome Scores for shoulder disorders, illustrating their potential pitfalls and limitations. Section B presents a summary of the Acromio-Clavicular Joint (ACJ) Consensus Summit, describing pioneering techniques to re-establish shoulder function after dislocation. Section C describes the current state of evidence of Rotator Cuff Disorders, providing novel theories regarding its underlying biomechanics and reconstruction techniques. The 2009-2013 ISAKOS UEC members hope the readers find this compendium an insightful update for daily shoulder management.
  • Digital
    James A. O'Leary, editor.
    Digital : Springer2009
    Preconceptual risk factors / James A. O'Leary -- Antepartum risk factors / James A. O'Leary -- Role of ultrasound in shoulder dystocia / James A. O'Leary -- Intrapartum risk factors / James A. O'Leary -- Pelvimetry / James A. O'Leary -- Recognition of disproportion / James A. O'Leary -- Delivery techniques / James A. O'Leary -- The McRoberts maneuver / James A. O'Leary -- Cephalic replacement : the Gunn-Zavanelli-O'Leary maneuver / James A. O'Leary -- Infant injury / James A. O'Leary -- In utero causation of brachial plexus injury : myth or mystery? / James A. O'Leary -- Recurrent shoulder dystocia / James A. O'Leary -- Predisposing factors for shoulder dystocia-related birth injuries : causation analysis / Leslie Iffy, Joseph J. Apuzzio, and Vijaya Raju -- Recognition, classification, and management of shoulder dystocia : the relationship to causation of brachial plexus injury / Michael S. Kreitzer -- Minimizing the risks of shoulder dystocia-related fetal injuries / Leslie Iffy -- The maternal fetal medicine viewpoint : causation and litigation / Barry S. Schifrin and Wayne R. Cohen -- Brachial plexus injury at cesarean section / Michael S. Kreitzer and James A. O'Leary -- Delivery of the nondiabetic macrosomic infant / Lisa Gittens-Williams -- The midwifery view of shoulder dystocia / Judith S. Mercer and Debra A. Erickson-Owens -- Recent research : relevant and reliable / James A. O'Leary -- Observations on the etiology of brachial plexus birth palsy based on radiographic, intraoperative, and histologic findings / Stephen M. Russell, Israel Alfonso, and John A.I. Grossman.
  • Digital
    [edited by] Matthew T. Provencher, Anthony A. Romeo.
    Digital : ClinicalKey2012
    "Shoulder Instability, by Drs. Mark Provencher and Anthony Romeo, is the first comprehensive resource that helps you apply emerging research to effectively manage this condition using today's best surgical and non-surgical approaches. Detailed illustrations and surgical and rehabilitation videos clearly demonstrate key techniques like bone loss treatment, non-operative rehabilitation methods, multidirectional instability, and more. You'll also have access to the full contents online at www.expertconsult.com. "-- Publisher's website.
  • Digital
    Giovanni Di Giacomo, Alberto Costantini, Andrea De Vita, Nicola de Gasperis (editors) ; forewords by James C. Esch, Gilles Walch.
    Digital : Springer2011
  • Digital
    Eiji Itoi, Guillermo Arce, Gregory I. Bain, Ronald L. Diercks, Dan Guttmann, Andreas B. Imhoff, Augustus D. Mazzocca, Hiroyuki Sugaya, Yon-Sik Yoo, editors.
    Digital : Springer2015
    Classification and Epidemiology: Classification of Stiff Shoulder -- Epidemiology. Etiology: Idiopathic -- Post-Traumatic -- Post Cuff Repair -- Post Instability Repair -- Other Post Surgical -- Other Causes (Cuff Disease, Impingement, Osteoarthritis, heterotopic ossification, etc). Anatomy and Biomechanics: Anatomy Related to the Range of Motion -- Biomechanics Related to the Range of Motion -- Rotator Interval and Stiffness. Examinations: Pathophysiology: Histology and Laboratory Tests -- Clinical Symptoms -- Physical Examinations -- Imaging. Conservative Treatment: Natural Course -- Conservative Treatment. Surgical Treatment: MUA -- Arthroscopic Release -- Postop. Rehabilitation Program -- Reported Outcomes and Results: What should we and the patient expect?.
  • Digital
    edited by Richard G.A. Feachem, Allison A. Phillips, and Geoffrey A. Targett, on behalf of the Malaria Elimination Group.
    Digital2009
    Print2009
    "Provides informed practical means of achieving and sustaining zero transmission. It is designed as a road map, providing direction and options from which to choose an appropriate path. The Prospectus reviews the operational, technical, and financial feasibility for those working on the front lines and outlines the tools that can be considered for an elimination program." "[summary]"--Provided by publisher.
  • Digital
    edited by Walter E. Goldstein.
    Digital : CRCnetBASE2011
    Chapter 1. Introduction / Walter E. Goldstein -- Chapter 2. Epidemiology and Health Effects in Moisture-Damaged Damp Buildings / Jean Cox-Ganser, Ju-Hyeong Park, Richard Kanwal -- Chapter 3. Mold Biology, Molecular Biology and Genetics / Edward Sobek -- Chapter 4. Products of Mold Associated with Sick Building Syndrome / Walter E. Goldstein -- Chapter 5. Mathematical Model of Mold Propagation and Product Formation in Building Materials, Inherent Transport Phenomena and Applications / Walter E. Goldstein, Willem A. Schreuder -- Chapter 6. Forensic Studies in Moldy-Damp Buildings / Philip R. Morey, Gary N. Crawford, Michael J. Cornwell, Brad Caddick, Tara Toren-Rudisill, Raoul Webb -- Chapter 7. Practices in Identifying, Remediating and Reoccupancy When Mold Occurs / Gary R. Brown -- Chapter 8. Analysis of Microscopic Contaminants in Sick Building Investigations / James Millette, Barb Epstien, Elliott Horner -- Chapter 9. Analytical Practice in Mold Identification and Solutions, Including Measurements and Sampling / Edward Sobek -- Chapter 10. Research and Development, Directions in Construction Practice and Summary Recommendations / Walter E. Goldstein.
  • Print
    by Lenwood G. Davis.
    Print1978-
    Status: Not Checked OutLane Catalog Record
  • Digital
    Fernando Ferreira Costa, Nicola Conran, editors.
    Digital : Springer2016
    Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease's pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.
  • Digital
    Jo Howard, Paul Telfer.
    Digital : Springer2015
    This practical clinical handbook reveals that sickle cell disease (SCD) is an increasingly common condition to manage in Europe and North America. SCD demands clinical expertise and experience as well as sensitivity to its social and cultural context. This book is designed to broaden readersℓ́ℓ knowledge in this challenging condition by describing the acute and long-term complications unique to SCD and that affect nearly every system of the body. Critically, it also details the significant recent advances in understanding the pathophysiology of SCD that are leading to novel treatment modalities. ℗ℓ Sickle Cell Disease in Clinical Practice promotes higher quality care by outlining the clinical problems as they arise, and covering essential background information, including up-to-date research, and useful points to guide management. As such, the intended target audience is broad and includes general physicians, general practitioners, hematologists, pediatricians, emergency medicine physicians, surgeons, medical students, nurse specialists and commissioners.
  • Digital
    Mario A. Dicato, editor.
    Digital : Springer2013
    Drug Interactions and Pharmacogenetics -- Breast Cancer -- Lung Cancer -- Gastrointestinal Cancer: Selection of Clinically Relevant Drug-Induced Toxicities Encountered in Gastrointestinal Cancer Treatment -- Gynecologic Cancer -- Genitourinary Cancer -- Central Nervous System -- Bone Marrow Toxicity: Red Blood Cells -- Bone Marrow Toxicity: White Blood Cells -- Dermatologic Side Effects of Systemic Anticancer Therapy -- Myeloid Malignancies -- Lymphoma -- Multiple Myeloma -- Preservation of Fertility in the Cancer Patient -- Cardiotoxicity -- Toxicity of Bone-Targeted Agents in Malignancy -- State of the Art of Antiemetic Therapy -- Side Effects of Nociceptive Cancer Pain Treatments in Adults -- Totally Implanted Access Ports: Indications and Prevention of Complications.
  • Print
    Douglas J. Gould, Jennifer K. Brueckner.
    Print2008
    Status: Not Checked OutLane Catalog Record
    Part I. Cerebrum -- 1. Surface of the Brain I -- 2. Surface of the Brain II -- 3. Divisions of the Brain and Brodmann's Areas -- 4. Membranes of the Brain -- 5. Blood Supply to the Brain -- 6. Ventricular System -- 7. The Corticospinal System : Course of Fibers from Cortex to Basal Ganglia -- 8. The Corticospinal System : Medial View -- Internal Capsule -- 9. The Corticospinal System : Introduction to Horizontal Sections -- 10. The Corticospinal System : White Matter Structures in Relation to Basal Ganglia -- 11. The Corticospinal System : Additional Relations to Deeper Structures -- 12. The Corticospinal System : Relations Among the Insula, Claustrum and White Matter Structures -- 13. The Corticospinal System : Relations of Basal Nuclei to Thalamus -- 14. The Corticospinal System, Basal Nuclei, and Thalamus -- 15. Relations Between the Thalamus and Cortex : Location of the Hypothalamus -- 16. Relations Between Cortex and Upper Brainstem : Sagittal Views -- 17. The Corticospinal System and Brainstem Structures : Midbrain -- 18. The Corticospinal System and Brainstem Structures : Pons and Medulla -- 19. The Decussation of the Pyramids -- 20. Representation of Body Parts in the Corticospinal System : Cortex and Brainstem -- 21. Lesions in the Corticospinal System -- 22. Clinical Signs of Corticospinal Damage -- Part II. Basal nuclei -- 23. Identification of the Basal Nuclei -- 24. Connections of the Basal Nuclei -- 25. Circuits within and with the Cerebrum, Cerebellum, and Spinal Cord -- 26. Pathways of the Extrapyramidal System -- 27. Blood Supply to the Basal Nuclei -- 28. Clinical Signs of Basal Nuclei Damage -- 29. Lesions of the Basal Nuclei -- Part III. Cerebellum -- 30. The Structure of the Cerebellum -- 31. Cerebellar Peduncles -- 32. Cerebellar Pathways -- 33. Blood Supply to the Cerebellum -- 34. Cerebellar Lesions -- 35. Clinical Signs of Cerebellar Damage -- Part IV. Diencephalon -- 36. Divisions of the Diencephalon -- 37. Connections of the Diencephalon -- 38. Thalamic Nuclei and Relationships -- 39. Hypothalamic Nuclei and Relationships -- 40. Blood Supply to the Diencephalon -- 41. Lesions of the Diencephalon -- 42. Clinical Signs of Damage to the Diencephalon -- Part V. Brainstem -- 43. Surface of the Brainstem -- 44. Intrinsic Anatomy of the Brainstem -- 45. Blood Supply to the Brainstem -- 46. Brainstem : Spinocerebellar Components of the Lower Medulla -- 47. Brainstem : Transition from Spinal Cord to Medulla, with Emphasis on the Kinesthetic Pathway -- 48. Brainstem : Spinal Trigeminal System in the Transition Zone from Spinal Cord to Medulla -- 49. Introduction to Motor Nuclei of the Brainstem -- 50. The Somatic Group of Brainstem Nuclei -- 51. The Branchial and Visceral Groups of Brainstem Motor Nuclei -- 52. Contributions of Brainstem Motor Nuclei to the Cranial Nerves -- 53. Location of Motor Nuclei on Phantom Views of Brainstem -- 54. Motor Nuclei and Other Landmarks in Transverse Sections Through the Brainstem -- 55. Somatic and Visceral Sensory Components of the Brainstem : Trigeminal System -- 56. Somatic and Visceral Sensory Components of the Brainstem, Concluded: Mesencephalic V and Solitarius Systems -- 57. Review of Cranial Nerve Compenents -- 58. Lesions of the Brainstem -- 59. Peripheral Lesions of the Cranial Nerves -- Part VI. Spinal cord -- 60. Spinal Cord : Relations between Spine and Spinal Cord -- 61. Blood Supply to the Spinal Cord -- 62. Identification of Cord Levels -- 63. White and Gray Matter of the Spinal Cord and Location of Corticospinal Tracts -- 64. The Types of Somesthetic Sensation : Relations between Peripheral Sensory Pathways and Spinal Cord -- 65. Location of Sensory Pathways in the White Matter of the Spinal Cord -- 66. Synapses in Sensory Pathways : Lateral and Anterior Spinothalamic Tracts -- 67. Synapses in Sensory Pathways : Posterior Columns and Spinocerebellar Tracts -- 68. Reflexes as Indications of Motor Disease -- 69. The Sympathetic Nervous System in the Spinal Cord -- 70. Review of Spinal Pathways : Clinical Examples -- 71. Review of Spinal Pathways : Further Clinical Examples -- 72. Lesions of the Spinal Cord -- 73. Membranes of the Spinal Cord -- Part VII. Special senses -- 74. Visual System -- 75. Chemical Senses -- 76. Auditory and Vestibular Systems.
  • Digital
    edited by Rae R. Matsumoto, Wayne D. Bowen and Tsung-Ping Su.
    Digital : Springer2007
    Print2007
  • Digital
    Sylvia B. Smith, Tsung-Ping Su, editors.
    Digital : Springer2017
    Print2017
    "Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types. It's putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer's disease, Parkinson's disease, Huntington's disease, pain, drug addiction and locomotor activity. Their roles in possible treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors. Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein"--Publisher's description.
  • Digital
    collection dirigeé par Marc Immenroth, Thorsten Berg, Jürgen Brenner ; auteurs, Gérard Champault, Hendrik Schimmelpenning ; avec le conours de Ann-Katrin Güler, Ute Stefani Haaga.
    Digital : Springer2009
  • Digital
    Changming Sun, Tomasz Bednarz, Tuan D. Pham, Pascal Vallotton, Dadong Wang, editors.
    Digital : Springer2015
    Print2015
    Signal and image analysis techniques are becoming more widely used in biomedical and life science applications. With an emphasis on applications of computational models for solving modern challenging problems in biomedical and life sciences, this book aims to bring collections of articles from biologists, medical/biomedical and health science researchers together with computational scientists to focus on problems at the frontier of biomedical and life sciences. The goals of this book are to build interactions of scientists across several disciplines and to help industrial users apply advanced computational techniques for solving practical biomedical and life science problems. This book is for users in the fields of biomedical and life sciences who wish to keep abreast with the latest techniques in signal and image analysis. The book presents a detailed description to some of the applications. It can be used by those both at graduate and specialist levels.
  • Digital
    Wim van Drongelen.
    Digital : ScienceDirect2010
    Lomb's algorithm and the Hilbert transform -- Modeling -- Volterra series -- Wiener series -- Poisson-Wiener series -- Decomposition of multichannel data -- Causality.

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