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all 577 "R" titles

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  • R and S-PLUS companion to multivariate analysis SU Catalog (SearchWorks), Click LINK above for location/circulation status.
    Print Material
  • R book 2007, Wiley
    Preface --1.Getting started --2.Essentials of the R language --3.Data input --4.Dataframes --5.Graphics --6.Tables --7.Mathematics --8.Classical tests --9.Statistical modelling --10.Regression --11.Analysis of variance --12.Analysis of covariance --13.Generalized linear models --14.Count data --15.Count data in tables --16.Proportion data --17.Binary response variables --18.Generalized additive models --19.Mixed-effects models --20.Non-linear regression --21.Tree models --22.Time series analysis --23.Multivariate statistics --24.Spatial statistics --25.Survival analysis --26.Simulation models --27.Changing the look of graphics --References and further reading --Index.
  • "Focusing on user-developed programming, An R Companion to Linear Statistical Models serves two audiences: Those who are familiar with the theory and applications of linear statistical models and wish to learn or enhance their skills in R; and those who are enrolled in an R-based course on regression and analysis of variance. For those who have never used R, the book begins with a self-contained introduction to R that lays the foundation for later chapters.This book includes extensive and carefully explained examples of how to write programs using the R programming language. These examples cover methods used for linear regression and designed experiments with up to two fixed-effects factors, including blocking variables and covariates. It also demonstrates applications of several pre-packaged functions for complex computational procedures"-- Provided by publisher.
  • R cookbook. 1st ed. 2011, ProQuest Safari
  • R for SAS and SPSS users SU Catalog (SearchWorks), Click LINK above for location/circulation status.
    Print Material
  • R graphics 2006, CRCnetBASE
  • R graphics. 2nd ed. 2011, CRCnetBASE
    An introduction to R graphics -- Traditional graphics. Simple usage of traditional graphics -- Customizing traditional graphics -- Grid graphics. Trellis graphics : the lattice package -- The grammar of graphics : the ggplot2 package -- The grid graphics model -- The grid graphics object model -- Developing new graphics functions and objects -- The graphics engine. Graphics formats -- Graphical parameters -- Graphics packages. Graphics extensions -- Plot extensions -- Graphics for categorical data -- Maps -- Node-and-edge graphs -- 3D graphics -- Dynamic and interactive graphics -- Importing graphics -- Combining graphics systems.
  • R graphs cookbook 2011, ProQuest Safari
  • R in a nutshell 2010, ProQuest Safari
  • R primer 2012, CRCnetBASE
  • Rabies 2002, ScienceDirect
  • History of rabies research -- Rabies virus -- Epidemiology -- Molecular epidemiology -- Rabies in terrestrial animals -- Bat rabies -- Human disease -- Pathogenesis -- Pathology -- Immunology -- Laboratory diagnosis of rabies -- Measures of rabies immunity -- Rabies vaccines -- Next generation of rabies vaccines -- Public health management of humans at risk -- Therapy of human rabies -- Dog rabies and its control -- Rabies control in wild carnivores -- Blueprint for rabies prevention and control -- Future developments and challenges.
  • Multi-Detector Row CT-Recent Developments, Radiation Dose and Dose Reduction Technologies /Thomas Flohr --Clinical Expansion of CT and Radiation Dose /Stuart Meeson, Rajesh Patel and Stephen Golding --Risks from Ionising Radiation /Kenneth H. Chadwick and Hendrik P. Leenhouts --The Cancer Risk from Low Level Radiation /Bernard L. Cohen --Image Quality in CT: Challenges and Perspectives /Thomas L Toth --Radiation Dose Metrics and the Effect of CT Scan Protocol Parameters /Sue Edyvean, Maria Lewis and Alan Britten --Scan Parameters and CT Radiation Dose /Sarabjeet Singh and Mannudeep K. Kalra --Optimization of Tube Potential for Radiation Dose Reduction in CT /Lifeng Yu, Joel G. Fletcher and Cynthia H. McCollough --Conventional and Newer Reconstruction Techniques in CT /Homer Pien, Synho Do, Sarabjeet Singh and Mannudeep K. Kalra --Image Noise Reduction Filters /Sarabjeet Singh and Mannudeep K. Kalra --Hardware Developments for Radiation Dose Reduction /Rich Mather --Application of Shielding in CT Radiation Dose Reduction /Shima Aran, Sarabjeet Singh and Mannudeep K. Kalra --Radiation Dose: Records and Audits /Tessa S. Cook, William W. Boonn and Woojin Kim --Collective Radiation Dose from MDCT: Critical Review of Surveys Studies /Georg Stamm.ALARA Concept for MDCT Optimization: What is Reasonable, What is Achievable? /Denis Tack --Automatic Exposure Control in Multidetector-row CT /Mannudeep K. Kalra --Patient Centering in MDCT: Dose Effects /Mannudeep K. Kalra and Thomas L. Toth --Dose Optimization and Reduction in CT of the Brain and Head and Neck Region /Tom Mulkens, Rodrigo Salgado and Patrick Bellinck --Dose Reduction and Optimization in Computed Tomography of the Chest /Pierre Alain Gevenois and Denis Tack --Dose Optimization and Reduction in MDCT of the Abdomen /Caroline Keyzer and Denis Tack --Radiation Dose Optimisation of Cardiac and Vascular MDCT in Adults and Paediatric Patients /Jean François Paul, Caroline Keyzer, Michelle Williams and Denis Tack --Dose Optimization and Reduction in Musculoskeletal CT Including the Spine /A. Gervaise, P. Teixeira, N. Villani, S. Lecocq and M. Louis, et al. --Dose Reduction in CT Fluoroscopy /N. Buls, F. Vandenbroucke and J. de Mey --Dose Optimization and Reduction in CT of Children /Peter Vock, Enno Stranzinger and Rainer Wolf --CT Scanning in Pregnancy /D. E. Litmanovich and A. A. Bankier --Radiation Risk Associated with Lung Cancer Screening /Cornelia Schaefer-Prokop, Krijn van Muiswinkel and Mathias Prokop.Dose Reduction in Screening Programs: Colon Cancer Screening /Thierry N. Boellaard, Henk W. Venema and Jaap Stoker --CT Dose Perspectives and Initiatives of the IAEA /Madan M. Rehani and Olivera Ciraj-Bjelac --The Image Gently Campaign: Championing Radiation Protection for Children Through Awareness, Educational Resources and Advocacy /Marilyn J. Goske, Michael J. Callahan, Donald P. Frush, Sue C. Kaste and Gregory Morrison, et al. --CT Radiation Dose and Safety: Perspectives at the U.S. Food and Drug Administration /Stanley H. Stern, Sean Boyd, Kish Chakrabarti, Iacovos S. Kyprianou and Thalia T. Mills, et al. --ICRP's Role in Patient Dose Management in CT /Madan M. Rehani --Software for Calculating Dose and Risk /Georg Stamm --Image Wisely /James A. Brink and E. Stephen Amis --Guidelines for Appropriate CT Imaging /Kristie M. Guite, J. Louis Hinshaw, Frank N. Ranallo and Fred T. Lee --Practical Approaches to Dose Reduction: GE Perspective /Roy A. Nilsen --Dose Reduction in Computed Tomography Siemens Perspective /Christianne Leidecker and Bernhard Schmidt --CT Radiation Dose: Philips Perspective /Alain Vlassenbroek, Dhruv Mehta and Jeffrey Yanof --Practical Approaches to Dose Reduction: Toshiba Perspective /Jacob Geleijns and R Irwan.
  • Ch. 1. Growing health concerns with respect to low doses of ionizing radiation : can we prevent and/or mitigate them? -- ch. 2. Physics of radiological weapons and nuclear reactors -- ch. 3. Acute radiation damage by high doses of ionizing radiation in humans -- ch. 4. Long-term damages among survivors of high doses of ionizing radiation -- ch. 5. Prevention and mitigation of acute radiation sickness (ARS) -- ch. 6. Prevention and mitigation of late adverse effects of high radiation doses -- ch. 7. Health risks of low doses of ionizing radiation -- ch. 8. Prevention and mitigation against radiological weapons and nuclear plant accidents -- ch. 9. Prevention and mitigation of damage after low radiation doses -- ch. 10. Implementation plans for prevention and mitigation of radiation injury -- ch. 11. Health risks of nonionizing radiation and their prevention and mitigation.
  • Radiation oncology 2008, Springer
  • Central Nervous System Tumors: Adult and Pediatric -- Skin Cancer -- Head and Neck Cancer -- Lung Cancer -- Tumors of the Mediastinum -- Breast Cancer -- Upper Gastrointestinal Cancers -- Lower Gastrointestinal Cancers -- Urinary System Cancers -- Male Genitourinary Cancer -- Gynecologic Malignancies -- Hematologic Malignancies -- Sarcoma -- Pediatric Non-central Nervous System Cancers -- Benign and Metastatic Disease.
  • Radiation Physics --Radiobiology --Clinical Radiation Oncology --Central Nervous System Tumors --Head and Neck Cancers --Lung Cancer --Breast Cancer --Genitourinary System Cancers --Gynecological Cancers --Gastrointestinal System Cancers --Soft Tissue Sarcoma --Skin Cancer --Lymphomas and Total Body Irradiation --Pediatric Tumors --Rare Tumors and Benign Diseases.
  • Ideal for on-the-spot consultation, this pocket manual, Radiation Oncology: Management Decisions, provides easily accessible information for residents and practitioners in radiation oncology. It presents the most essential information that is immediately required in the clinical setting. The first eight chapters of the book focus on key basic concepts; the remaining 46 chapters describe treatment regimens for all cancer sites and tumor types. Includes coverage of pain and palliation, and covers all latest therapeutic techniques. This edition includes expanded information on image-guided therapy, 3D techniques, and 4D protocols. The updated cancer staging guidelines have been used throughout the manual. In addition, there is a brand-new chapter devoted to QUANTEC dosage recommendations.
  • This book explains clearly and in detail all aspects of radiation protection in nuclear medicine. After an introductory chapter on the general role of radiation protection, measurement quantities and units are discussed, and detectors and dosimeters, described. Radiation biology and radiation dosimetry are then addressed, with the inclusion of a chapter specifically devoted to biology and dosimetry for the lens of the eye. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter focuses on quality assurance and reference levels. Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. The book closes by considering exposure of the public and summarizing the "rules of thumb" for radiation protection in nuclear medicine. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts.
  • History of radiation therapy in dermatology -- Radiobiology -- Physical aspects of dermatological radiotherapy -- Radiation protection -- Staging of squamous cell carcinoma and basal cell carcinoma -- Acute and chronic cutaneous reactions to radiotherapy -- Efficacy of superficial radiotherapy -- Treatment selection for superficial radiotherapy -- Superficial radiation therapy treatment planning -- Current use of dermatologic radiotherapy in the United States -- Grenz ray therapy -- Radiotherapy for cutaneous squamous and basal cell carcinomas -- Brachytherapy -- Cutaneous merkel cell carcinoma -- Radiotherapy for cutaneous angiosarcoma -- Radiotherapy for dermatofibrosarcoma protuberans -- Squamous and basal cell carcinomas with perineural invasion -- Getting started in superficial radiation for the dermatology practice.
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    Atomic structure and radioactive decay -- Production of x rays -- Interactions of x rays and gamma rays -- Radiation units -- Measurement of ionizing radiation -- Calibration of megavoltage beams of x rays and electrons -- Dosimetry of radiation fields -- Treatment planning by manual methods -- Diagnostic imaging and applications to radiation therapy -- Computer systems -- Computer-based treatment planning -- Sources for implant therapy -- Brachytherapy treatment planning -- Radiation protection -- Quality assurance -- Advances in radiation therapy -- Answers to selected problems.
  • Radiation toxicity 2006, Springer
  • Nuclear Radiation, Ionization, and Radioactivity -- Radiation Exposure: Consequences, Detection, and Measurements -- Mathematical Modeling of Radiation -- Medical Imaging -- Basic Principles of Radiation Detectors -- Theoretical Approach of Crystal and Film Growths of Materials Used in Medical Imaging System -- Device Fabrication (Scintillators/Radiation Detectors) -- Characterization of Radiation Detectors (Scintillators) Used in Nuclear Medicine -- Instrumentation and Its Applications in Nuclear Medicine.
  • Radical prostatectomy 2014, Springer
    Radical Prostatectomy: Surgical Perspectives provides surgeons with a comprehensive overview of the anatomical approach to radical prostatectomy, whether done through an open (retropubic) or robotic-assisted laparoscopic approach. All chapters are structured to provide a step-by-step approach to the most technically demanding and most common oncologic procedure in urology surgery. The book includes highly practical presentations of typical surgical patients seen in the clinical practice of urology and relies heavily on illustrations and intraoperative photographs to clearly complement the text. In addition, the book ?includes a detailed description of the management of uncommon but potentially serious intraoperative complications, including major vascular injury, ureteral transaction, and rectotomy. Written by authors from a variety of integrated disciplines, including anesthesia, cardiology, and nursing Radical Prostatectomy: Surgical Perspectives is a unique and valuable resource in the field of urology both for those currently in training and for those already in surgical practices.
  • Origins and discovery -- Nuclear energetics -- Radioactivity and nuclear reactions -- Types of radioactive decay -- Transmutation research -- Archaeology and dating -- Radioisotopes in medicine -- Scientific and industrial applications -- Radiation and the environment.
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    Physics and chemistry of radiation absorption -- DNA strand breaks and chromosomal aberrations -- Cell survival curves -- Radiosensitivity and cell age in the mitotic cycle -- Repair of radiation damage and the dose-rate effect -- Oxygen effect and reoxygenation -- Linear energy transfer and relative biologic effectiveness -- Acute effects of total-body irradiation -- Radioprotectors -- Radiation carcinogenesis -- Hereditary effects of radiation -- Effects of radiation on the embryo and fetus -- Radiation cataractogenesis -- Doses and risks in diagnostic radiology, interventional radiology and cardiology, and nuclear medicine -- Radiation protection -- Molecular techniques in radiobiology -- Cancer biology -- Dose-response relationships for model normal tissues -- Clinical response of normal tissues -- Model tumor systems -- Cell, tissue, and tumor kinetics -- Time, dose, and fractionation in radiotherapy -- Predictive assays -- Alternative radiation modalities -- Radiosensitizers and bioreductive drugs -- Gene therapy -- Chemotherapeutic agents from the perspective of the radiation biologist -- Hyperthermia.
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    Physics and Chemistry of Radiation Absorption -- Molecular Mechanisms of DNA and Chromosome Damage and Repair -- Cell Survival Curves -- Radiosensitivity and Cell Age in the Mitotic Cycle -- Fractionated Radiation and the Dose-Rate Effect -- Oxygen Effect and Reoxygenation -- Linear Energy Transfer and Relative Biologic Effectiveness -- Acute Radiation Syndrome -- Radioprotectors -- Radiation Carcinogenesis -- Heritable Effects of Radiation -- Effects of Radiation on the Embryo and Fetus -- Radiation Cataractogenesis -- Radiologic Terrorism -- Molecular Imaging -- Doses and Risks in Diagnostic Radiology, Interventional Radiology and Cardiology, and Nuclear Medicine -- Radiation Protection -- Cancer Biology -- Dose-Response Relationships for Model Normal Tissues -- Clinical Response of Normal Tissues -- Model Tumor Systems -- Cell, Tissue, and Tumor Kinetics -- Time, Dose, and Fractionation in Radiotherapy -- Retreatment after Radiotherapy: The Possibilities and the Perils -- Alternative Radiation Modalities -- The Biology and Exploitation of Tumor Hypoxia -- Chemotherapeutic Agents from the Perspective of the Radiation Biologist -- Hyperthermia.
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  • Radioguided surgery 2008, Springer
    Part I. Chemistry and Physics -- Radiopharmaceuticals for Radioguided Surgery / Esteban Obenaus, Paola A. Erba, Marco Chinol, Christophe Van de Wiele and Gyozo A. Janoki, et al. -- Physical Performance Parameters of Intraoperative Probes / Carlo Chiesa, Francesca Toscano, Mario Mariani and Emilio Bombardieri -- Positron-Sensitive Probes / Schlomo Schneebaum, Richard Essner and Einat Even-Sapir -- Gamma Ray Imaging Probes for Radioguided Surgery and Site-Directed Biopsy / Francesco Scopinaro and Alessandro Soluri -- Radiation Protection in Radioguided Surgery / Edwin C. Glass and Wendy A. Waddington -- Training and Credentialing for Radioguided Surgery / Eric D. Whitman -- Part II. Sentinel Lymph Nodes -- The Anatomy and Physiology of Lymphatic Circulation / Preya Ananthakrishnan, Giuliano Mariani, Luciano Moresco and Armando E. Giuliano -- The Role of Lymph Node Staging for Clinical Decision Making in Patients with Solid Cancers / Fausto Badellino, Ilaria Pastina, Elisa Borsò, Sergio Ricci and H. William Strauss, et al. -- Sentinel Lymph Node Biopsy in Patients with Breast Cancer / Charles E. Cox, John M. Cox, Giuliano Mariani, Caren E.G. Wilkie and Laura B. White, et al. -- Sentinel Lymph Node Biopsy in Cutaneous Melanoma / Jeffrey E. Gershenwald, Roger F. Uren, Giuliano Mariani and John F. Thompson -- Dynamic Sentinel Lymph Node Biopsy in Penile Carcinoma / Simon Horenblas, Bin K. Kroon, Renato A. Valdés Olmos and Omgo E. Nieweg -- Sentinel Lymph Node Biopsy in Cancer of the Head and Neck / Luca Calabrese, David Soutar, Jochen Werner, Roberto Bruschini and Concetta De Cicco, et al. -- Sentinel Lymph Node Biopsy in Gynecologic Malignancies / Emilio Bombardieri, Marco Maccauro, Rosanna Fontanelli, Francesco Raspagliesi and Giovanni Paganelli -- Sentinel Lymph Node Biopsy in Cancers of the Gastrointestinal Tract / Yuko Kitagawa, Sukamal Saha and Masaki Kitajima --Sentinel Lymph Node Biopsy in Prostatic Cancer / Alexander Winter, Harry Vogt, Dorothea Weckermann, Rolf Harzmann and Friedhelm Wawroschek -- Radioguided Biopsy of the Sentinel Lymph Node in Patients with Non-Small Cell Lung Cancer / Giuseppe Boni, Gianpiero Manca, Franca M. A. Melfi, Marco Lucchi and Alfredo Mussi, et al. -- Sentinel Lymph Node Biopsy in Thyroid Cancer / Massimo Salvatori, Domenico Rubello, Michael J. O'Doherty, Maria Rosa Pelizzo and Giuliano Mariani -- Histopathology of Sentinel Lymph Nodes / Giuseppe Viale, Giovanni Mazzarol and Eugenio Maiorano -- Frozen Section and Imprint Cytology in Sentinel Lymph Node Biopsy for Breast Cancer / Santo V. Nicosia and Charles E. Cox -- Molecular Assessment of Sentinel Lymph Nodes / Farin Amersi, Armando E. Giuliano and Dave S.B. Hoon -- Part III. Occult Lesion Localization -- Where It All Began: The Heritage of Radioimmunoguided Surgery / Fausto Badellino, Mario Roselli, Marzio Perri, Fiorella Guadagni and Giuliano Mariani -- Radioguided Occult Lesion Localization in the Breast / Giovanni Paganelli, Concetta De Cicco, Giovanna Gatti and Alberto Luini -- Minimally Invasive Radioguided Parathyroidectomy in Primary Hyperparathyroidism / James Norman, Domenico Rubello, Armando E. Giuliano and Giuliano Mariani -- Radioguided Surgery of Neuroendocrine Tumors / Richard P. Baum, Sergio Sandrucci and Stefan Adams -- Radioguided Surgery of Solitary Pulmonary Nodules / Giuseppe Boni, Franca M. A. Melfi, Gianpiero Manca, Marco Lucchi and Alfredo Mussi, et al. -- Radioguided Surgery of Occult Lesions in Patients with Thyroid Cancer / Domenico Rubello, Massimo Salvatori, Maria Rosa Pelizzo, Giuseppe Boni and Giuliano Mariani -- Radioguided Bone Lesion Localization / Gianpiero Manca, Giuliano Mariani and Lary A. Robinson.
  • Three years after the publication of the first edition, Radiological Anatomy for FRCR Part 1 remains the best seller in its category based on its faithful representation of the examination. This second edition is designed to reflect the change in exam format introduced in spring 2013. It includes two new chapters as well as some new cases in the remaining chapters and tests. Under the new exam format, candidates will be presented with 100 cases, with a single question per case and a single mark for the correct answer. This book covers all core topics addressed by the exam in a series of tests and includes chapters focussing specifically on paediatric cases and normal anatomical variants. The answers to questions, along with explanations and tips, are supplied at the end of each chapter. Care has been taken throughout to simulate the exam itself. The book aims not to replace the already available literature on radiological anatomy but rather to complement it as a revision guide. It will help candidates to identify the level of anatomical knowledge expected by the Royal College of Radiologists.
  • Radiological English 2007, Springer
  • Embryology and Anatomy of the Neonatal Chest / Stephanie Ryan -- Update on Clinical Management of Neonatal Chest Conditions / Anne Twomey -- Computed and Digital Radiography in Neonatal Chest Examination / Amaka C. Offiah -- Hyaline Membrane Disease and Complications of Its Treatment / Veronica Donoghue -- Transient Tachypnoea of the Newborn / Veronica Donoghue -- Meconium Aspiration / Catherine M. Owens -- Diagnostic Imaging of Neonatal Pneumonia / David Manson -- Antenatal Imaging of Chest Malformations / Laurent Garel -- Postnatal Imaging of Chest Malformations / Stephanie Ryan -- Congenital Anomalies of the Neonatal Upper Airway / David Manson -- Computed Tomography of the Central and Peripheral Airways / Alistair D. Calder and Catherine M. Owens -- Ultrasound of the Neonatal Thorax / Ingmar Gassner and Theresa E. Geley -- Ultrasound in Congenital Heart Disease / Colin J. McMahon and Benjamin W. Eidem -- Magnetic Resonance Imaging in Congenital Heart Disease / Christian J. Kellenberger -- Chest Radiography in Congenital Heart Disease / Bjarne Smevik -- Angiocardiography and Intervention in Congenital Heart and Great Vessel Disease / Bjarne Smevik and Per G. Bjørnstad -- Computed Tomography in Congenital Heart Disease / Laureen Sena and Hyun Woo Goo -- Chest Wall Abnormalities which Cause Neonatal Respiratory Distress / Georg F. Eich.
  • Radiological protection 2005, Springer
  • Radiological Safety and Quality - Paradigms in Leadership and Innovation is a multi-disciplinary and inter-sectorial collaboration by international experts and leaders from academic institutions, radiology practices, professional organizations, regulatory authorities, UN and international agencies. Established principles and new concepts, challenges and opportunities, and examples of leadership and innovations are discussed to raise awareness, share experience and facilitate development of facility-based or system-wide improvements in radiation safety, quality radiology, and patient care by procedure justification, optimization of protection and imaging data, and incident minimization. The 26 chapters by 53 experts and 11 messages from international organizations and agencies convey a common theme: there is no single panacea to improve radiological safety and quality but on-going leadership, innovation, collaboration, and stakeholder participation are needed.
  • Introduction --Introduction /Antonio Zicca, Alberto Tagliafico --Upper limb --Shoulder /Erica Fisci, Alberto Tagliafico --Elbow /Alberto Tagliafico, Carlo Martinoli --Wrist /Alberto Tagliafico, Carlo Martinoli --Lower limb --Hip /Alberto Tagliafico, Erica Fisci, Carlo Martinoli --Knee /Alberto Tagliafico, Carlo Martinoli --Ankle /Bianca Bignotti, Carlo Martinoli, Alberto Tagliafico --Spine --Spine /Erica Fisci, Alberto Tagliafico
  • Radiology 2006, Springer
    Musculoskeletal radiology -- Chest radiology -- Gastrointestinal radiology -- Genitourinary radiology -- Head and neck radiology -- Vascular and interventional -- Nuclear medicine -- Ultrasound -- Pediatrics -- Breast -- Neuroradiology.
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    Radiography, computed tomography, magnetic resonance imaging, and ultrasonography: principles and indications / Willam E. Erkonen -- Chest / William E. Erkonen -- Abdomen / Edmund A. Franken Jr. -- Pediatric imaging / Wilbur L. Smith -- Musculoskeletal system / William E. Erkonen and Carol A. Boles -- Spine and pelvis / Carol A. Boles -- Brain / Wilbur L. Smith -- Head and neck / Yutaka Sato -- Nuclear imaging / David L. Bushnell -- Mammography / William E. Erkonen, Laurie L. Fajardo and John W. Boardman -- Interventional radiology / Thomas A. Farrell and Monte L. Harvill.
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    Radiography, computed tomography, magnetic resonance imaging, and ultrasonography : principles and indications / William E. Erkonen and Vincent A. Magnotta -- Chest / William E. Erkonen and Brad H. Thompson -- Abdomen / Edmund A. Franken, Jr. -- Pediatric imaging / Wilbur L. Smith -- Musculoskeletal system / William E. Erkonen and Carol A. Boles -- Spine and pelvis / Carol A. Boles --Brain / Wilbur L. Smith -- Head and neck / Yutaka Sato -- Nuclear imaging / David L. Bushnell, Jr. -- Breast imaging / Jeong Mi Park, William E. Erkonen, and Laurie L. Fajardo -- Interventional radiology / Thomas A. Farrell.
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  • Radiology education 2009, Springer
    Introduction: Transforming radiology education through scholarship -- The genesis and application of radiology education: mind the gap -- Scholarship in radiology education -- Today's radiology student: what every radiology training program director needs to know -- Teaching and learning: defining the scholarship of teaching -- Interdisciplinary learning: a stimulant for reflective practice -- Feedback in radiologic education -- The role of mentoring in professional education -- Radiological and biomedical knowledge integration: the ontological way -- Educational insights about professional ethics in radiology -- Learning in practice: new approaches to professional development for radiologists -- Acquiring competencies in radiology: the canMEDS model -- Technologies for teaching: exploring the use of PACS, databases, and teaching files -- Portable imaging systems for interactive teaching of radiography, computed tomography and ultrasound imaging principles -- Medical education research: challenges and opportunities in the scholarship of discovery -- Developing a radiology curriculum for a new medical school in Singapore -- Leadership in radiology education -- The business of radiology education scholarship -- Radiology education in Southeast Asia: current status and pedagogical challenges -- Training of ultrasound doctors and educational reform in West China hospital of Sichuan University, China -- Teaching radiology at the Angkor hospital for children in Siem Reap, Cambodia -- Teaching radiology in Latin America: images from Peru -- Using the world wide web to develop competencies around the globe -- The role of a learned society in promotion and dissemination of knowledge -- Radiology education in the faculty of medicine at Cairo University (Kasr Al-Ainy hospital).
  • Radiology education 2012, Springer
    Part 1.Evaluation and Assessment for Non-educators --The Nature of Professional Expertise /Penelope Engel-Hills and Rethy K. Chhem --Fundamentals of Assessment and Evaluation: Clarifying Terminology /Kathryn M. Hibbert, Teresa Van Deven and Soveacha Ros --Competence in the Professions: Expanding Opportunities and Emerging Practices /Kathryn M. Hibbert and Rethy K. Chhem --Medical Competency in Postgraduate Medical Training Programs /Thomas N. B. Pascual, Soveacha Ros, Penelope Engel-Hills and Rethy K. Chhem --Part 2.Evaluation and assessment in Radiology education --Philosophical Considerations in Educational Assessment /Richard B. Gunderman --Competencies and Experiential Requirements in Radiology Training /Shih-chang Wang --Accreditation and Evaluation of Programs: The Canadian Perspective /Kenneth A. Harris, Margaret A. Kennedy and Sarah Taber --Assessment and Evaluation in a Transnational Radiodiagnosis Training Program /Shih-chang Wang --Part 3.Case Studies: Theory into practice --Strategies and Actions to Improve Risk Communication Competency in Radiation Medicine /Lawrence S. Lau, Kwan-Hoong Ng and Rethy K. Chhem --Assessing Clinical Competence in Radiation Oncology Education /Eduardo Rosenblatt, Bruce G. Haffty and Jan Willem Leer --Measuring Competence of Radiology Education Programs and Residents: The Egyptian Experience /Sahar N. Saleem and Youssriah Y. Sabri --Assessing Residents in a Nuclear Medicine Physician Training Program: The Philippine Experience /Thomas N. B. Pascual, Jerry M. Obaldo, Teofilo O. L. San Luis and Marcela J. Leus --Clinical Training in Medical Physics: IAEA Perspective /Ahmed Meghzifene, Donald Mclean, Debbie Van Der Merwe and Brian Thomas --Assessing Diagnostic Radiology Training: The Singapore Journey /Bien-Soo Tan, Lynette L. S. Teo, Daniel E. S. Wong, Shaun X. J. M. Chan and Kiang-Hiong Tay --Assessment of Radiation Oncology Medical Physics Residents: The London, Ontario (Canada) Experience /Jacob Van Dyk and Jerry J. Battista.
  • Patient Radiation Safety and Risk -- Introduction to Radiology Concepts -- Conventional Radiology -- Ultrasound -- Computed Tomography -- MRI -- Nuclear Medicine -- Cardiovascular and Interventional Radiology -- Heart and Mediastinum -- Lateral Chest -- Pulmonary Mass Lesions -- Air Space Disease -- Interstitial Disease -- Atelectasis -- Pulmonary Vasculature -- Pulmonary Edema -- Pneumothorax -- Miscellaneous Chest Conditions -- Tubes and Lines -- Breast Imaging -- Women's Ultrasound -- Women's Health Interventions -- Abdominal Calcifications -- Abnormal Air Collections in the Abdomen -- Barium Studies of the Upper GI Tract -- Barium Enema & CT Colonography -- Bowel Obstruction -- Inflammatory Bowel Disease -- Defecography -- Intra-abdominal Lymphadenopathy -- The Gallbladder -- Abdominal & Pelvic Pain Evaluation -- Imaging of the Trauma Patient -- Concerning Lesions -- Incidental Lesions -- Radionucleotide Evaluation of GI Bleeding -- Radionucleotide Bone Imaging -- Lung Ventilation and Perfusion Imaging -- Radionucleotide Cardiac Imaging -- F-18 FDG Positron Emission Tomography -- Diagnostic Arteriography -- Pulmonary Arteriography & IVC Filter Placement -- Percutaneous Nephrostomy Placement -- TIPS -- Central Venous Access -- Fractures -- Part 1 -- Fractures -- Part 2 -- Arthritides -- Bone Tumor Characterstics -- CNS Anatomy -- The Cervical Spine -- Head Trauma -- Stroke -- Headache and back pain -- Radiology coming soon.
  • Part 1.Ultrasound and Transvaginal Ultrasound: Techniques, Normal Findings, and Variations.Introduction /Min Hoan Moon and Jung Sik Kim --Illustrations /Min Hoan Moon and Jung Sik Kim --pt. 2.Gynecologic CT and MRI: Techniques and Normal Findings.Introduction /Sung Il Jung and Bohyun Kim --Illustrations /Sung Il Jung and Bohyun Kim --pt. 3.Variations and Congenital Anomalies of the Female Genital Tract.Introduction /Jeong Kon Kim --Illustrations /Jeong Kon Kim --pt. 4.Uterine Myoma.Introduction /Byung Kwan Park --Illustrations /Byung Kwan Park --pt. 5.Adenomyosis.Introduction /Byung Kwan Park --Illustrations /Byung Kwan Park --pt. 6.Imaging Evaluation of Uterine Cervical Carcinoma.Introduction /Seung Hyup Kim and Kyung-Sik Cho --Illustrations /Seung Hyup Kim and Kyung-Sik Cho --pt. 7.Endometrial Cancer.Introduction /Sung Il Hwang and Seung Hyup Kim --Illustrations /Sung Il Hwang and Seung Hyup Kim.pt. 8.Miscellaneous Tumors of the Uterus.Introduction /Yu Ri Shin and Sung Eun Rha --Illustrations /Yu Ri Shin and Sung Eun Rha --pt. 9.Post-treatment Changes and Recurrence of Uterine Malignancies.Introduction /Dae Chul Jung and Kie Hwan Kim --Illustrations /Dae Chul Jung and Kie Hwan Kim --pt. 10.Gestational Trophoblastic Diseases.Introduction /Jae Young Byun and Seung Eun Jung --Illustrations /Jae Young Byun and Seung Eun Jung --pt. 11.Miscellaneous Diseases of the Uterus.Introduction /Seung Eun Jung and Jae Young Byun --Illustrations /Seung Eun Jung and Jae Young Byun --pt. 12.Ovarian Cysts and Cystic Disease.Introduction /Hyuck Jae Choi --Illustrations /Hyuck Jae Choi --pt. 13.Ovarian Tumors: General Considerations and Mode of Spread.Introduction /Min Hoan Moon --Illustrations /Min Hoan Moon --pt. 14.Epithelial Tumors of the Ovary.Introduction /Sung Bin Park and Min Hoan Moon --Illustrations /Sung Bin Park and Min Hoan Moon.pt. 15.Germ Cell Tumors of the Ovary.Introduction /Sun Ho Kim --Illustrations /Sun Ho Kim --pt. 16.Sex Cord-Stromal Tumors of the Ovary.Introduction /Jung Suk Sim --Illustrations /Jung Suk Sim --pt. 17.Miscellaneous Tumors of the Ovary and Adnexa.Introduction /Chang Kyu Sung and Jung Suk Sim --Illustrations /Chang Kyu Sung and Jung Suk Sim --pt. 18.Endometriosis.Introduction /Hyun Lee and Jeong Yeon Cho --Illustrations /Hyun Lee and Jeong Yeon Cho --pt. 19.Adnexal Torsion.Introduction /Sung Eun Rha and Young-Hwa Kim --Illustrations /Sung Eun Rha and Young-Hwa Kim --pt. 20.Pelvic Inflammatory Disease and Tubo-ovarian Abscess.Introduction /Jeong Yeon Cho --Illustrations /Jeong Yeon Cho --pt. 21.Ectopic Pregnancy.Introduction /Min Hoan Moon and Young-Ho Lee --Illustrations /Min Hoan Moon and Young-Ho Lee.pt. 22.Vagina and Vulva.Introduction /Sun Ho Kim and Bohyun Kim --Illustrations /Sun Ho Kim and Bohyun Kim --pt. 23.Vascular Diseases of the Female Pelvis.Introduction /Seong Jin Park --Illustrations /Seong Jin Park --pt. 24.Pediatric Gynecologic Diseases./Introduction /So-Young Yoo and Woo Sun Kim --Illustrations /So-Young Yoo and Woo Sun Kim --pt. 25.Nongynecologic Lesions Mimicking Gynecologic Diseases.Introduction /Bum Sang Cho and Seung Hyup Kim --Illustrations /Bum Sang Cho and Seung Hyup Kim --pt. 26.Hysterosalpingography.Introduction /Hak Jong Lee --Illustrations /Hak Jong Lee --pt. 27.Sonohysterography.Introduction /Eun Ju Lee --Illustrations /Eun Ju Lee --pt. 28.Gynecologic Nonvascular Interventions.Introduction /See Hyung Kim and Seung Hyup Kim --Illustrations /See Hyung Kim and Seung Hyup Kim --pt. 29.Obstetric and Gynecologic Vascular Interventions.Introduction /Man-Deuk Kim and Jin Wook Chung --Illustrations.
  • Radiology Illustrated: Hepatobiliary and Pancreatic Radiology is the first of two volumes that will serve as a clear, practical guide to the diagnostic imaging of abdominal diseases. This volume, devoted to diseases of the liver, biliary tree, gallbladder, pancreas, and spleen, covers congenital disorders, vascular diseases, benign and malignant tumors, and infectious conditions. Liver transplantation, evaluation of the therapeutic response of hepatocellular carcinoma, trauma, and post-treatment complications are also addressed. The book presents approximately 560 cases with more than 2100 carefully selected and categorized illustrations, along with key text messages and tables, that will allow the reader easily to recall the relevant images as an aid to differential diagnosis. At the end of each text message, key points are summarized to facilitate rapid review and learning. In addition, brief descriptions of each clinical problem are provided, followed by both common and uncommon case studies that illustrate the role of different imaging modalities, such as ultrasound, radiography, CT, and MRI.
  • Radiology Illustrated: Spine is an up-to-date, superbly illustrated reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. Common, critical, and rare but distinctive spinal disorders are described succinctly with the aid of images highlighting important features and informative schematic illustrations. The first part of the book, on common spinal disorders, is for radiology residents and other clinicians who are embarking on the interpretation of spinal images. A range of key disorders are then presented, including infectious spondylitis, cervical trauma, spinal cord disorders, spinal tumors, congenital disorders, uncommon degenerative disorders, inflammatory arthritides, and vascular malformations. The third part is devoted to rare but clinically significant spinal disorders with characteristic imaging features, and the book closes by presenting practical tips that will assist in the interpretation of confusing cases.
  • Uroradiology is an up-to-date, image-oriented reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. All aspects of the imaging of urologic diseases are covered, and case studies illustrate the findings obtained with the relevant imaging modalities in both common and uncommon conditions. Most chapters focus on a particular clinical problem, but normal findings, congenital anomalies, and interventions are also discussed and illustrated.In this second edition, the range and quality of the illustrations have been enhanced, and many schematic drawings have been added to help readers memorize characteristic imaging findings through pattern recognition. The accompanying text is concise and informative. Besides serving as an outstanding aid to differential diagnosis, this book will provide a user-friendly review tool for certification or recertification in radiology.
  • Radiology of HIV/AIDS 2014, Springer
    Molecular Biology of HIV/AIDS and Its Clinical Management -- An Overview of Clinical Immunology of HIV/AIDS -- An Overview of Clinical Microbiology of HIV/AIDS -- Epidemiological Investigation of AIDS -- Pathogenetic and Pathological Mechanism -- Clinical Manifestations of HIV/AIDS Infection -- Laboratory Test and Special Examinations -- Diagnostic Imaging -- AIDS Imaging and Evidence Based Medicine -- Clinical Medication Against HIV/AIDS -- Introduction to Assessment and Monitoring of Critical AIDS -- HIV Related Effect Factors -- HIV/AIDS Related Nervous System Diseases -- HIV/AIDS Related Myeleterosisand Peripheral Neuropathy -- HIV/AIDS Related Eye Diseases -- HIV/AIDS Related Neck Diseases -- HIV/AIDS Related Respiratory Diseases -- HIV/AIDS Related Cardiac Diseases -- HIV/AIDS Related Gastrointestinal Diseases -- HIV/AIDS Related Hepatobiliary, Pancreatic and Splenic Diseases -- HIV/AIDS Related Peritoneal and Retroperitoneal Disease -- HIV/AIDS Related Urogenital Disease -- HIV/AIDS Related Musculoskeletal Diseases -- HIV/AIDS Related Pediatric Diseases -- HIV/AIDS Related Skin Diseases -- Functional Imaging of HIV/AIDS.
  • A novel strain of influenza A (H1N1) virus emerged and an outbreak of influenza A (H1N1) occurred worldwide in 2009 and 2010, posing a severe threat to the health of human beings. The two Editors work together in Beijing You An Hospital, to combat this type of influenza. This book, Radiology of Influenza A (H1N1), is intended to provide first-hand clinical data and its scientific analysis, thus supporting sound clinical practice for influenza A (H1N1) prevention and treatment as well as related scientific research. The authors have collected over 100 critical influenza A (H1N1) virus-infected cases. For cases of influenza A (H1N1) that resulted in death, autopsies were performed for 8 cases after receiving their families' informed consent. Over 200 reports on pathological and histological analysis as well as immunohistochemical and electroscopic analysis were brought together. This book was then compiled by comparing the published data with the present first-hand data. This book includes a wealth of content, including DR, CT and MRI images, pathological and histological figures, and immunohistochemical and electroscopic figures. Related research, clinical and educational needs can be readily satisfied by its detailed data, texts and figures, as well as typical case reports. Li Hongjun, is professor and director of the diagnostic radiology department in Beijing You An Hospital, affiliated with Capital Medical University, Beijing, China. Li Ning, is professor and president of Beijing You An Hospital, affiliated with Capital Medical University, Beijing, China.
  • Introduction to radiology -- Head and neck -- Thorax -- Abdomen -- Pelvis -- Extremities: general overview -- Upper extremity -- Lower extremity.
  • Introduction to the Post Surgical Abdomen / Alan G. Chalmers, David Macafee, Damian J. M. Tolan and John Brittenden -- The Esophagus / Damian J. M. Tolan, Keith M. Harris, Deepak Prasad and Samir P. Mehta -- The Stomach and Duodenum / Damian J. M. Tolan, Keith M. Harris, Deepak Prasad and Samir P. Mehta -- The Pancreas / Krishna Menon, John Brittenden, Simon McPherson, Nikhil M. Bhuskute and Andrew Smith -- The Biliary Tree / Vamshi P. Jagadesham, Maria Sheridan, J. Peter A. Lodge and John Brittenden -- The Liver / J. Ashley Guthrie, Hajamohideen M. Salahudeen and J. Peter A. Lodge -- The Small Bowel / James C. Lenton, Adeshina S. Fawole, John Brittenden and Damian J. M. Tolan -- The Colon / Chris Macklin, John Brittenden, David Jayne and Damian J. M. Tolan -- Genitourinary System / Christopher Wilkinson.
  • "The book describes the disease entities, radiologic symptoms., as well as lists of differential diagnosis"--Provided by publisher.
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  • This atlas fills a gap in the literature by documenting in detail the role of nuclear medicine imaging of infection and inflammation. The pathophysiologic and molecular mechanisms on which radionuclide imaging of infection/inflammation is based are clearly explained, but the prime focus of the book is on the clinical relevance of such procedures. Their impact is demonstrated by a collection of richly illustrated teaching cases that describe the most commonly observed scintigraphic patterns, as well as anatomic variants and technical pitfalls. Due attention is paid to the application of recently developed techniques, including multimodality fusion imaging such as SPECT/CT and PET/CT. Emphasis is placed in particular on the ability of multimodality imaging to increase both the sensitivity and the specificity of radionuclide imaging. This atlas will be an excellent learning tool for residents in nuclear medicine and illuminating for other specialists with an interest in the field. Learning tool especially useful for residents in nuclear medicine and for specialists in nuclear medicine approaching the field. Useful integration for residents and for specialists also in infectious and autoimmune diseases, as well as in orthopedics.
  • Radiopharmaceuticals 2011, CRCnetBASE
    "This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It examines the relative benefits of various radiopharmaceuticals and provides guidance on dose estimation and agent selection. Utilizing figures of merit for quantitative assessment, it covers standard medical internal radiation dose (MIRD), absorbed dose method for imaging agents, vivo methods for obtaining activity data, errors of activity estimation techniques, phantom-based and patient-based dose estimates and their associated uncertainties, and options available to clinical physicists. Supported by numerous examples from clinical trials, it discusses two and three dimensional estimation processes, including modern hybrid scanners such as SPECT/CT and PET/CT"--Provided by publisher.
  • Radiotracers and drug registration -- Radioactivity and radiotracers -- The study of drug metabolism using radiotracers -- DNA binding, isotope dilution and other uses of radiotracers -- Quantitative whole-body autoradiography (QWBA) -- Scintillation counting -- Statistics in liquid scintillation counting -- Instrumentation for detection of radioactivity -- Sample preparation for liquid scintillation counting -- Biomedical accelerator mass spectrometry -- Positron emission tomography -- Gamma scintigraphy and SPECT.
  • Rails. 2nd ed. SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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  • Radial Forearm Flap -- Lateral Arm Flap -- Anterolateral Thigh / Vastus Lateralis Flap -- Latissimus Dorsi Flap -- Scapular Flap -- Fibular Flap -- Klaus-Dietrich Wolff and Frank Hölzle -- Iliac Crest Bone Flap -- Perforator Flaps -- Anterolateral Thigh Perforator Flap -- Soleus Perforator Flap -- Deep Inferior Epigastric Artery Perforator Flap.
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  • Introduction and scope --Magnitude of Raman scattering --Collection and detection of Raman scattering --Signal-to-noise in Raman spectroscopy --Instrumentation overview and spectrometer performance --Sampling modes in Raman spectroscopy --Lasers for Roman spectroscopy --Dispersive Raman spectrometers --Nondispersive Raman spectrometers --Calibration and validation --Raman microscopy and imaging --Fiber-optic Raman sampling --Raman spectroscopy of surfaces.
  • "Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable devices, nonimplantable devices, rehabilitation, psychoteherapy, and behavioral interventions. This book focuses on the methods of assessing nonpharmacological treatments, highlighting specific issues and discussing all possible design of trials. It provides practical examples to underline the issues and solutions in assessing nonpharmacological treatment in trials. Arguably the first book to exclusively explore this topic, it discusses various categories of treatments from surgical procedures to psychotherapy"--Provided by publisher.
  • In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an experimental therapy with a prospective control therapy.
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  • Rapid contextual design 2005, ScienceDirect
  • The Rapids are a series of reference and revision pocket books that cover key facts in a simple and memorable way. Each book contains the common conditions that students and newly qualified nurses encounter on the wards, in the community, and on placements. Only the basic core relevant facts are provided to ensure that these books are perfect and concise rapid refreshers. Rapid Infection Control Nursing is an essential read for all frontline nursing staff working in hospitals or community settings. Designed for quick reference, it explores the essential principles of infection.
  • Epidemiology and databases -- Rare and uncommon gynecological cancers: a clinical guide -- The contribution of diagnostic imaging in rare gynecological malignancies -- Mucinous cancers: ovary -- Pseudomyxoma peritonei -- Ovarian clear cell carcinoma -- Clear cell carcinoma of the ovary -- The continuum of serious ovarian tumors of low malignant potential and low-grade serous carcinoma of the ovary -- Sex cord-stromal tumors -- Squamous cell carcinomas arising from dermoids -- Ovarian carcinosarcomas -- Small cell and neuroendocrine cancers of the ovary -- Primary ovarian carcinoids and neuro-endocrine tumors including struma ovarii -- Reed uterine carcinosarcomas -- Leiomyosarcomas of uterus -- Mucinous tumors of the uterine corpus -- Clear cell cancers of uterus -- Small cell and neuroendocrine cancers of the cervix -- Primary malignant melanoma of the vulva and vagina -- Gynecologic cancers in pregnancy: guidelines of an international consensus meeting.
  • Rare diseases-avoiding misperceptions and establishing realities : the need for reliable epidemiological data / Stephen C. Groft and Manuel Posada de la Paz -- Rare diseases epidemiology research / Manuel Posada de la Paz ... [et al.] -- Evidence-based medicine and rare diseases / Simon Day -- Prevention, diagnosis, and services / Eva Bermejo and María Luisa Martínez-Frías -- The importance of case reports in advancing scientific knowledge of rare diseases / John C. Carey -- Patient registries : utility, validity, and inference / Rachel Richesson and Kendra Vehik -- Biobanking in rare disorders / Hanns Lochmüller and Peter Schneiderat -- Evaluation of the validity and utility of genetic testing for rare diseases / Scott D. Grosse, Lisa Kalman, and Muin J. Khoury -- Population-based surveillance for rare congenital and inherited disorders : models and challenges / Jodi M. Jackson, Krista S. Crider, and Richard S. Olney -- Statistical methods for the geographical analysis of rare diseases / Virgilio Gómez-Rubio and Antonio López-Quílez -- Clinical trials and rare diseases / Joachim Werner Otto Gerss and Wolfgang Köpcke -- A regulatory overview about rare diseases / Jordi Llinares -- Economic considerations in the provision of treatments for rare diseases / Christopher McCabe, Richard Edlin, and Jeff Round -- Rare diseases social epidemiology : analysis of inequalities / Anna Kole and François Faurisson -- Quality of life and rare diseases / Luis Rajmil, Lilisbeth Perestelo-Pérez, and Michael Herdman -- Cost of illness and economic evaluation in rare diseases / Julio López-Bastida and Juan Oliva-Moreno -- The burden of rare cancers in Europe / Gemma Gatta ... [et al.] -- Hereditary channelopathies in neurology / Karin Jurkat-Rott ... [et al.] -- Osteochondral diseases and fibrodysplasia ossificans progressiva / Antonio Morales-Piga and Frederick S. Kaplan -- The prevalence of congenital anomalies in Europe / Helen Dolk, Maria Loane, and Ester Garne -- Rare autoimmune diseases / Arrigo Schieppati and Erica Daina -- Epidemiology of rare anaemias in Europe / Beatrice Gulbis ... [et al.] -- Inherited metabolic rare disease / Teresa Pampols -- The contribution of rare diseases to understanding the epidemiology of neurodevelopmental disabilities / Diana Schendel, Catherine Rice, and Christopher Cunniff -- Creating a European Union framework for actions in the field of rare diseases / Antoni Montserrat Moliner -- National plans and strategies on rare diseases in Europe / Domenica Taruscio, Luciano Vittozzi, and Rumen Stefanov -- Ethical aspects on rare diseases / Luis A. Barrera and Gilberto Cely Galindo -- Advocacy groups and their role in rare diseases research / Mary Dunkle, Wayne Pines, and Peter L. Saltonstall.
  • Rare lymphomas 2014, Springer
    The past decade has witnessed tremendous progress in the diagnostic and therapeutic approaches to malignant lymphoma as well as in understanding of the underlying molecular pathogenesis. Optimal treatment strategies are now based not only on accurate diagnosis but also on thorough evaluation of clinical and molecular risk factors. Even more importantly, molecular targeted approaches have been shown to be effective in the treatment of distinct lymphoma subtypes. Against this background, clinical management of especially the rare lymphomas remains a challenge for the general oncologist. This book provides a comprehensive overview of current treatment strategies in these rare lymphoma subtypes. Experts in the field from around the world describe the histomorphology in a clinically relevant manner, consider the role of risk factors in detail, and discuss the spectrum of therapeutic approaches. Special emphasis is placed on the translation of molecular science into clinical care, and a disease-specific algorithm is proposed for each entity. This book will prove an excellent resource for both experienced and inexperienced practitioners.
  • This is the first book to be devoted exclusively to rare tumors in children and adolescents, and its aim is to provide up-to-date information on their diagnosis and clinical management. The opening section of the book addresses general issues including epidemiology, risk factors/etiology, biology and genetics, prevention, early detection, and screening. It also discusses solutions to assist in the management of rare tumors, such as international networking and internet platforms, thus providing the reader with access to the developing clinical network for rare tumors in children. In the second section, specific malignancies are described, with practical guidance on diagnostic workup, multimodal therapy, survival outcome, follow-up, and adverse effects. These chapters are organized by site according to the clinician{u2019}s approach to the patient. Each chapter includes an introduction to the differential diagnostic assessment of tumors at the site in question, encompassing both frequent and rare tumor types. This approach should enable the clinician to take rare entities into account during the diagnostic assessment, so that the initial diagnostic steps are performed optimally. Each chapter goes on to provide detailed therapeutic guidelines for specific rare tumors. The authors are a multidisciplinary group of specialists who have dedicated themselves to this group of tumors. This well-illustrated book will prove an invaluable source of information for all pediatricians and oncologists faced with the often difficult task of diagnosing and treating rare tumors in the pediatric age group.
  • RAS family GTPases 2006, Springer
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  • Rat nervous system. 3rd ed. 2004, ScienceDirect
  • Machine generated contents note: 1 Anatomical Differences in the Peripheral Auditory System of Mammals and Man -- Felix, H. (Zfirich) -- 11 Neurotransmission in the Human Labyrinth -- Schrott-Fischer, A.; Kammen-Jolly, K.; Scholtz, A.W. (Innsbruck); -- Kong, W.-J. (Hua-Zhong); Eybalin, M. (Montpellier) -- 18 Different Action of Memantine and Caroverine on Glutamatergic Transmission in the Mammalian Cochlea -- Oestreicher, E. (Munich/Berne); Ehrenberger, K. (Vienna); Felix, D. (Berne) -- 26 Role of Substance P in the PeripheralVestibular and Auditory System -- Felix, H. (Zirich); Oestreicher, E. (Munich/Berne); Felix, D. (Berne); -- Ehrenberger, K. (Vienna) -- Hair Cells - Ion Channels -- 35 Calcium Channels in Mouse Hair Cells: Function, Properties and Pharmacology -- Engel, J.; Michna, M. (Tiibingen); Platzer, J.; Striessnig, J. (Innsbruck) -- 42 Adrenergic and Muscarinic Control of Cochlear Endolymph Production -- Wangemann, P. (Manhattan) -- 51 Cochlear Blood Flow Regulation -- Wangemann, P. (Manhattan) -- 58 ETA Receptors in the Gerbil Spiral Modiolar Artery -- Scherer, E.Q.; Wangemann, P. (Manhattan) -- Immunology - Cell Cycle -- 66 Immunological Damage to the Inner Ear: Current and Future Therapeutic Strategies -- Ryan, A.F. (San Diego/La Jolla); Pak, K.; Low, W; Battaglia, A.; Mullen, L.; -- Harris, J.P.; Keithley, E.M. (San Diego) -- 75 Pharmacological Influence on Inner Ear Endothelial Cells in Relation to the Pathogenesis of Sensorineural Hearing Loss -- Gloddek, B.; Lamm, K.; Arnold, W. (Munich) -- 84 Mpv17 Mouse Strain -A Model for the Relationship between the Kidney and the Inner Ear -- Meyer zum Gottesberge, A.M.; Balz, V. (Diisseldorf); Felix, H. (Zurich) -- Ototoxicity, Noise and Aging -- 91 Sensitivity to Glutamate Neurotoxicity in Different Developmental Periods of the Rat Cochlea -- Carricondo, F; Bartolome, M.V; Vicente-Torres, M.A.; Fernmndez-Pacheco, P.; -- Rodriguez, T.; Gil-Loyzaga, P. (Madrid) -- 96 Protective Mechanisms of Sound Conditioning -- Niu, X.; Canlon, B. (Stockholm) -- 106 Effects of Aging on C57BL/6J Mice: An Electrophysiological and Morphological Study -- Bartolom6, M.V; del Castillo, E.; L6pez, L.M.; Carricondo, F.; Poch-Broto, J.; -- Gil-Loyzaga, P. (Madrid) -- 112 Effects of Aging on Cochlear MonoamineTurnover -- Vicente-Torres, M.A.; Davila, D.; Mufioz, E.; Gil-Loyzaga, P. (Madrid) -- 116 Degeneration Pattern of Human First-Order Cochlear Neurons -- Felix, H.; Pollak, A. (Zfirich); Gleeson, M. (London); Johnsson, L.-G. (Helsinki) -- 124 The Inner Hair Cell Afferent/Efferent Synapses Revisited: A Basis for New Therapeutic Strategies -- Puel, J.-L.; Ruel, J.; Guitton, M.; Pujol, R. (Montpellier) -- 131 Neurotransmission of the Cochlear Inner Hair Cell Synapse - Implications for Inner Ear Therapy -- Oestreicher, E. (Munich/Berne); Arnold, W. (Munich); Felix, D. (Berne) -- 140 Simulation of Methods for Drug Delivery to the Cochlear Fluids -- Salt, A.N. (St. Louis) -- 149 Transtympanic Endoscopy for Drug Delivery to the Inner Ear Using a New Microendoscope -- Plontke, S.K.-R. (Tuibingen); Plinkert, PK.; Plinkert, B. (Tiibingen/Homburg, Saar); -- Koitschev, A.; Zenner, H.-P.; L6wenheim, H. (Tiibingen) -- 156 Clinical Experience with Caroverine in Inner Ear Diseases -- Ehrenberger, K. (Vienna).
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  • Razoxane and dexrazoxane 2010, Springer
    "Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms. They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc. The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer's disease could be stabilized by one or both these drugs."--P. [4] of cover.
  • Rb and tumorigenesis 2006, Springer
    Rb as a positive transcriptional regulator during epithelial differentiation / Chantal E. Crémisi and Linda L. Pritchard -- pRb in the differentiation of normal and neoplastic cells / Deborah Pajalunga, Grazia Camarda and Marco Crescenzi -- Regulation of DNA replication by the retinoblastoma tumor suppressor protein / Erik S. Knudsen and Steven P. Angus -- New insights into transcriptional regulation by Rb : one size no longer fits all / Peggy J. Farnham -- Regulation of Rb function by noncyclin dependent kinases / Jaya Padmanabhan and Srikumar P. Chellappan -- Diverse regulatory functions of the E2F family of transcription factors / Fred Dick and Nicholas Dyson -- Regulation of E2F-responsive genes through histone modifications / Estelle Nicolas, Laetitia Daury and Didier Trouche -- Emerging roles for the retinoblastoma gene family / Jacqueline L. Vanderluit, Kerry L. Ferguson and Ruth S. Slack -- Rb and cellular differentiation / Lucia Latella and Pier Lorenzo Puri.
  • Re-irradiation 2011, Springer
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    "Tell the doctor where it hurts." It sounds simple enough, unless the problem affects the very organ that produces awareness and generates speech. What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound: A figure skater whose body has become a ticking time-bomb. A salesman who drives around and around a traffic rotary, unable to get off. A college quarterback who can't stop calling the same play. A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive. A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth living. How does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance"-- Provided by publisher.
  • Machine generated contents note: 1.Introduction -- Format of the Exercise -- What Is Attachment? -- The Place of Attachment in Nature -- The Process of Attachment in Early Childhood -- Definition of Reactive Attachment Disorder (RAD) -- Differential Diagnosis -- Comorbidity -- 2.Vignette of "Jorge" -- pt. 1 Jorge as a Toddler -- Case Point: International Adoption -- pt. 2 Jorge at Preschool Age -- Case Point: Neglect, Growth, and Medical Problems -- pt. 3 Jorge in Kindergarten -- Case Point: The Retrospective Evaluation of Child Abuse -- pt. 4 Jorge in First Grade -- Case Point: Alexythymia and Attachment -- pt. 5 Jorge in Second and Third Grades -- Case Point: Longitudinal Course and the Trait of Indiscriminate Friendliness -- pt. 6 Jorge in fourth and fourth Grades -- Test #1 Case-Related Questions -- 3.Theories for the Origin of RAD -- pt. 1 Biological Basis -- Genetic Coding of Attachment -- Epigenetic Models -- Biological Effect of Maternal Stress -- Maturation and Lesions of Early Limbic Pathways -- Stress Tolerance and the Developing Brain -- Physiological Measurement of Attachment Disorder -- pt. 2 Psychological Factors -- A Deficit Model -- The Application of Joint Attention to Attachment -- Avoidance and Detachment -- The Phenomenon of Shame -- The Impact of Trauma -- pt. 3 Social Origins -- Attachment and Social Impairment -- Theory of Mind and the False Belief Test -- Anticipatory Interactive Planning -- 4.A Discussion and Critique of RAD -- 5.Therapy for RAD -- Test #2 Theory Questions -- B.Matching Section.
  • Reactive oxygen metabolites 2001, CRCnetBASE
  • Reading as a perceptual process 2000, ScienceDirect
  • The drug discovery business to date -- The drug discovery business to come -- Industrial considerations -- how things get done : the project team -- Project considerations -- Hit generation -- Turning hits into drugs -- Initial properties -- ADME and PK properties -- Toxicity related properties -- A career in drug discovery research.
  • Real-time PCR SU Catalog (SearchWorks), Click LINK above for location/circulation status.
    Print Material
    An introduction to real-time PCR / Gregory L. Shipley -- Data analysis and reporting / Pamela Scott Adams -- Relative quantification / Michael W. Pfaffl -- Normalization / Jim Huggett, Keertan Dheda and Stephen A. Bustin -- High-throughput primer and probe design / Xiaowei Wang and Brian Seed -- Quantitative analysis of ocular gene expression / Stuart N. Peirson -- Quantitative gene expression by real-time PCR / Thomas D. Schmittgen -- Real-time PCR using SYBR Green / Frederique Ponchel -- High-resolution melting analysis for scanning and genotyping / Virginie Dujols ... [et al.] -- Quantitative analyses of DNA methylation / Lin Zhou and James (Jianming) Tang -- Mitochondrial DNA analysis / Steve E. Durham and Patrick F. Chinnery -- Real-time immuno-PCR / Kristina Lind and Mikael Kubista -- Clinical microbiology / Burcu Cakilci and Mehmet Gunduz -- Clinical virology / David M. Whiley and Theo P. Sloots -- Solid organ transplant monitoring / Omaima M. Sabek -- Real-time PCR applications in hematology / Anne M. Sproul -- Real-time PCR for prenatal diagnosis of monogenic diseases caused by single nucleotide changes / Joanne Traeger-Synodinos, Christina Vrettou and Emmanuel Kanavakis.
  • Real-time systems 2002, Wiley
    ch. 1. Introduction, p. 1-9 -- ch. 2. Analysis and Verification of Non-Real-Time Systems, p. 10-40 -- ch. 3. Real-Time Scheduling and Schedulability Analysis, p. 41-85 -- ch. 4. Model Checking of Finite-State Systems, p. 86-133 -- ch. 5. Visual Formalism, Statecharts, and Statemate, p. 134-147 -- ch. 6. Real-Time Logic, Graph-Theoretic Analysis, and Modechart, p. 148-186 -- ch. 7. Verification Using Timed Automata, p. 187-211 -- ch. 8. Timed Petri Nets, p. 212-236 -- ch. 9. Process Algebra, p. 237-258 -- ch. 10. Design and Analysis of Propositional-Logic Rule-Based Systems, p. 259-366 -- ch. 11. Timing Analysis of Predicate-Logic Rule-Based Systems, p. 367-435 -- ch. 12. Optimization of Rule-Based Systems, p. 436-465.
  • Technology and 3D Imaging --3D TEE Basic Views --Native Cardiac Valves --Cardiac Prosthetic Valves --Left and Right Ventricles 3D Imaging --Cardiomyopathy Ventricles 3D Imaging --Aorta --Cardiac Masses 3D Imaging --Congenital Heart 3D Imaging --Miscellaneous 3D Imaging.
  • Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super.
  • Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays * Discusses many new assays developed since the previous edition. Presents recent developments in cytometric intrumentation/technology.
  • Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays. Discusses many new assays developed since the previous edition * Presents recent developments in cytometric intrumentation/technology.
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    Gap junctions, fast oscillations and the initiation of seizures / Roger D. Traub ... [et al.] -- Functional role of proinflammatory and anti-inflammatory cytokines in seizures / Annamaria Vezzani ... [et al.] -- Using the immune system to target epilepsy / Deborah Young and Matthew J. During -- Cortical dysplasis and epilepsy / Philip A. Schwartzkroin, Steven N. Roper and H. Jurgen Wenzel -- Malformations of cortical development / Peter B. Crino -- Functional implications of seizure-induced neurogenesis / Helen E. Scharfman -- Febrile seizures and mechanisms of epileptogenesis / Roland A. Bender, Celine Dubé and Tallie Z. Baram -- The tetanus toxin model of chronic epilepsy / T.A. Benke and J. Swann -- Brain stimulation as a therapy for epilepsy / Jeffrey H. Goodman.Genetic approaches to studying mouse models of human seizure disorders / Yan Yang and Wayne N. Frankel -- Integrins, synaptic plasticity and epileptogenesis / Christine M. Gall and Gary Lynch -- The role of BDNF in epilepsy and other diseases of the mature nervous system / Devin K. Binder -- Vascular endothelial growth factor (VEGF) in seizures / Susan D. Croll, Jeffrey H. Goodman and Helen E. Scharfman -- Plasticity mechanisms underlying mGluR-induced epileptogenesis / Robert K.S. Wong, Shih-Chieh Chuang and Riccardo Bianchi -- Role of the GABA transporter in epilepsy / George Richerson and Yuanming Wu -- GABA and its receptors in epilepsy / Günther Sperk ... [et al.] -- Role of the depolarizing GABA response in epilepsy / Kevin Staley --
  • Recent advances in nucleosides 2002, ScienceDirect
  • Introduction / Jean-Pierre Bocquet-Appel -- From genes to numbers : effective population sizes in human origins / John Hawks -- Assessment of land surveys in Greece : contributions and limitations / Jean-Nicolas Corvisier -- Estimation of an age distribution with its confidence intervals using an iterative Bayesian procedure and a bootstrap sampling approach / Jean-Pierre Bocquet-Appel and Jean-Noël Bacro -- Model life tables for pre-industrial populations : first application in palaeodemography / Isabelle Séguy ... [et al.] -- The Halley band for paleodemographic mortality analysis / Marc A. Luy and Ursula Wittwer-Backofen -- Modeling Paleolithic predator-prey dynamics and the effects of hunting pressure on prey "choice" / Mary C. Stiner ... [et al.] -- The demography of prehistoric fishing/hunting people : a case study of the Upper Columbia area / Nathan B. Goodale, Ian Kuijt, Anna M. Prentiss -- The paleodemography of central Portugal and the Mesolithic-Neolithic transition / Mary Jackes and Christopher Meiklejohn -- The Libben Site : a hunting, fishing, and gathering village from the Eastern Late Woodlands of North America : analysis and implications for palaeodemography and human origins / Richard S. Meindl, Robert P. Mensforth, C. Owen Lovejoy.
  • Section I. Animal models of PD -- Chapter 1. What have we learned from Drosophila models of Parkinson's disease? / Ming Guo -- Chapter 2. Neurotoxic in vivo models of Parkinson's disease: recent advances / Jason R. Cannon, J. Timothy Greenamyre -- Chapter 3. Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease / Stephen B. Dunnett, Mariah Lelos -- Chapter 4. Genetic mouse models of Parkinson's disease: The state of the art / Iddo Magen, Marie-Françoise Chesselet -- Chapter 5. Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease / Ayse Ulusoy, Mickael Decressac, Deniz Kirik, Anders Björklund -- Chapter 6. Modeling neuroinflammatory pathogenesis of Parkinson's disease / Christopher J. Barnum, Malú G. Tansey -- Chapter 7. The MPTP-lesioned non-human primate models of Parkinson's disease. Past, present, and future / Susan H. Fox, Jonathan M. Brotchie -- Section II. Exploring PD with brain imaging. -- Chapter 8. Abnormal metabolic brain networks in Parkinson's disease: from blackboard to bedside / Chris C. Tang, David Eidelberg -- Chapter 9. Imaging the nigrostriatal system to monitor disease progression and treatment-induced complications / Renju Kuriakose, A. Jon Stoessl -- Chapter 10. Brain imaging after neural transplantation / Marios Politis, Paola Piccini -- Chapter 11. Imaging non-motor aspects of Parkinson's disease / David J. Brooks, Nicola Pavese -- Section III. Frontiers in PD treatment -- Chapter 12. Gene therapy for dopamine replacement / Tomas Björklund, Erik Ahlm Cederfjäll, Deniz Kirik -- Chapter 13. Neurotrophic factor therapy for Parkinson's disease / Suresh Babu Rangasamy, Katherine Soderstrom, Roy A.E. Bakay, Jeffrey H. Kordower -- Chapter 14. Neural grafting in Parkinson's disease: Problems and possibilities / Patrik Brundin, Roger A. Barker, Malin Parmar -- CHAPTER 15. Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia / Emma L. Lane, Anders Björklund, Stephen B. Dunnett, Christian Winkler -- Chapter 16. Deep brain stimulation: state of the art and novel stimulation targets / Francisco A. Ponce, Andres M. Lozano -- Chapter 17. The challenge of non-motor symptoms in Parkinson's disease / K. Ray Chaudhuri, Per Odin.
  • Section I. Genetic and molecular mechanisms of neurodegeneration in PD -- Chapter 1. Identifying PD-causing genes and genetic susceptibility factors: Current approaches and future prospects / Thomas Gasser -- Chapter 2. The impact of genetic research on our understanding of Parkinson's disease / Ian Martin, Valina L. Dawson, Ted M. Dawson -- Chapter 3. Unravelling the role of defective genes / Mark R. Cookson -- Chapter 4. What causes the death of dopaminergic neurons in Parkinson's disease? / D. James Surmeier, Jaime N. Guzman, Javier Sanchez-Padilla, Joshua A. Goldberg -- Chapter 5. Intracellular signalling pathways in dopamine cell death and axonal degeneration / Robert E. Burke -- Chapter 6. Control of mitochondrial integrity in Parkinson's disease / Cristofol Vives-Bauza, Maja Tocilescu, Rosa L.A. deVries, Dana M. Alessi, Vernice Jackson-Lewis, Serge Przedborski -- Chapter 7. Role of post-translational modifications in modulating the structure, function and toxicity of α-synuclein: Implications for Parkinson's disease pathogenesis and therapies / Abid Oueslati, Margot Fournier, Hilal A. Lashuel -- Section II. Cellular and system-level pathophysiology of the basal ganglia in PD -- Chapter 8. The role of dopamine in modulating the structure and function of striatal circuits / D. James Surmeier, Weixing Shen, Michelle Day, Tracy Gertler, Savio Chan, Xianyong Tian, Joshua L. Plotkin -- Chapter 9. Assemblies of glutamate receptor subunits with post-synaptic density proteins and their alterations in Parkinson's disease / Fabrizio Gardoni, Veronica Ghiglieri, Monica di Luca, Paolo Calabresi -- Chapter 10. Pathophysiological roles for purines: Adenosine, caffeine and urate / Micaela Morelli, Anna R. Carta, Anil Kachroo, Michael A. Schwarzschild -- Chapter 11. Maladaptive striatal plasticity in l-DOPA-induced dyskinesia / M. Angela Cenci, Christine Konradi -- Chapter 12. Effects of GPi and STN inactivation on physiological, motor, cognitive and motivational processes in animal models of Parkinson's disease / Christelle Baunez, Paolo Gubellini -- Chapter 13. Computational physiology of the basal ganglia in Parkinson's disease / Michal Rivlin-Etzion, Shlomo Elias, Gali Heimer, Hagai Bergman -- Chapter 14. Neurocomputational models of motor and cognitive deficits in Parkinson's disease / Thomas V. Wiecki, Michael J. Frank.
  • Aging and the seven sins of memory / Benton H. Pierce, Jon S. Simons and Daniel L. Schacter -- Age-related changes in visual attention / David J. Madden and Wythe L. Whiting -- Studies of aging, hypertension and cognitive functioning : with contributions from the Maine-Syracuse study / Merrill F. Elias ... [et al.] -- A life span view of emotional functioning in adulthood and old age / Susan T. Charles and Laura L. Carstensen -- Personality and self-esteem development across the life span / Kali H.Trzesniewski ... [et al.] -- The evolving concept of subjective well-being : the multifaceted nature of happiness / Ed Diener, Christie Napa Scollon and Richard E. Lucas -- A cultural lens on biopsychosocial models of aging / James S. Jackson, Toni C. Antonucci and Edna Brown.
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  • Amoeba provide insight into the origin of virulence in pathogenic fungi / Arturo Casadevall -- Of model hosts and man: using Caenorhabditis elegans, Drosophila melanogaster and Galleria mellonella as model hosts for infectious disease research / Justin Glavis-Bloom, Maged Muhammed, and Eleftherios Mylonakis -- Caenorhabditis elegans as an alternative model to study senescence of host defense and the prevention by immunonutrition / Tomomi Komura ... [et al.] -- Bacterial effectors: learning on the fly / Laurent Boyer ... [et al.] -- Drosophilia asthma model: what the fly tells us about inflammatory diseases of the lung / Thomas Roeder ... [et al.] -- Elucidating the in vivo targets of Photorhabdus toxins in real-time using Drosophilia embryos / Isabella Vlisidou, Nicholas Waterfield, and Will Wood -- Ecological niche modeling as a tool for understanding distributions and interactions of vectors, hosts, and etiologic agents of Chagas disease / Jane Costa and A. Townsend Peterson -- Where simplicity meets complexity: Hydra, a model for host-microbe interactions / René Augustin ... [et al.] -- Tick as a model for the study of primitive complement system / Petr Kopacek, Ondrej Hajdusek, and Veronika Buresova -- Model hosts for the study of oral candidiasis / Juliana Campos Junqueira -- Creating a pro-survival and anti-inflammatory phenotype by modulation of acetylation in models of hemorrhagic and septic shock / Yongqing Li and Hasan B. Alam.
  • Receptor binding techniques. 2nd ed. 2005, Springer Protocols
    Receptor databases and computational websites for ligand binding -- Identification of orphan G protein-coupled receptor ligands using FLIPR assays -- Quantitative analysis of orphan G protein-coupled receptor mRNAs by TaqMan real-time PCR: G2A and GPR4 lysophospholipid receptor expression in leukocytes and in a rat myocardial infarction-heart failure model -- mRNA: detection by in situ and northern hybridization -- Radioligand-binding and molecular-imaging techniques for the quantitative analysis of established and emerging orphan receptor systems -- Measurement of radioligand binding by scintillation proximity assay -- Autoradiography of enzymes, second messenger systems, and ion channels -- Immunocytochemical localization of receptors using light and confocal microscopy with application to the phenotypic characterization of knock-out mice -- Live cell imaging of G protein-coupled receptors --Imaging and characterization of radioligands for positron emission tomography using quantitative phosphor imaging autoradiography -- Dynamic in vivo imaging of receptors in small animals using positron emission tomography.
  • Receptor-receptor interactions 2013, ScienceDirect
    This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes. With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come.
  • Recoding 2010, Springer
    Part I. Redefinition -- 1. Selenocysteine Biosynthesis, Selenoproteins, and Selenoproteomes / Vadim N. Gladyshev and Dolph L. Hatfield -- 2. Reprogramming the Ribosome for Selenoprotein Expression: RNA Elements and Protein Factors / Marla J. Berry and Michael T. Howard -- 3. Translation of UAG as Pyrrolysine / Joseph A. Krzycki -- 4. Specification of Standard Amino Acids by Stop Codons / Olivier Namy and Jean-Pierre Rousset -- 5. Ribosome “Skipping”: “Stop-Carry On” or “StopGo” Translation / Jeremy D. Brown and Martin D. Ryan -- 6. Recoding Therapies for Genetic Diseases / Kim M. Keeling and David M. Bedwell -- Part II. Frameshifting - Redirection of Linear Readout -- 7. Pseudoknot-Dependent Programmed -1 Ribosomal Frameshifting: Structures, Mechanisms and Models / Ian Brierley, Robert J.C. Gilbert, and Simon Pennell -- 8. Programmed -1 Ribosomal Frameshift in the Human Immunodeficiency Virus of Type 1 / Léa Brakier-Gingras and Dominic Dulude -- 9. Ribosomal Frameshifting in Decoding Plant Viral RNAs / W. Allen Miller and David P. Giedroc -- 10. Programmed Frameshifting in Budding Yeast / Philip J. Farabaugh -- 11. Recoding in Bacteriophages / Roger W. Hendrix -- 12. Programmed Ribosomal -1 Frameshifting as a Tradition: The Bacterial Transposable Elements of the IS3 Family / Olivier Fayet and Marie-Françoise Prère -- 13. Autoregulatory Frameshifting in Antizyme Gene Expression Governs Polyamine Levels from Yeast to Mammals / Ivaylo P. Ivanov and Senya Matsufuji -- 14. Sequences Promoting Recoding Are Singular Genomic Elements / Pavel V. Baranov and Olga Gurvich -- 15. Mutants That Affect Recoding / Jonathan D. Dinman and Michael O'Connor -- 16. The E Site and Its Importance for Improving Accuracy and Preventing Frameshifts / Markus Pech, Oliver Vesper, Hiroshi Yamamoto, Daniel N. Wilson, and Knud H. Nierhaus -- Part III. Discontiguity -- 17. Translational Bypassing - Peptidyl-tRNA Re-pairing at Non-overlapping Sites / Norma M. Wills -- 18. trans-Translation / Kenneth C. Keiler and Dennis M. Lee -- Part IV. Transcription Slippage -- 19. Transcript Slippage and Recoding / Michael Anikin, Vadim Molodtsov, Dmitry Temiakov, and William T. McAllister -- Part V. Appendix -- 20. Computational Resources for Studying Recoding / Andrew E. Firth, Michaël Bekaert, and Pavel V. Baranov.
  • Fulltext (pt. B) ScienceDirect
  • This book is intended to help practitioners understand the causes and effects of disordered breathing and to provide strategies and protocols to help restore normal function. Fully updated throughout, this volume has been completely revised to guide the practitioner in the recognition of breathing pattern disorders and presents the latest research findings relating to the condition including a range of completely new techniques - many from an international perspective - to help restore and maintain normal functionality. Video clips on an associated website presents practical examples of the breathing techniques discussed in the book. Carefully prepared by a global team of renowned experts under the guidance of Leon Chaitow Focuses on practical, validated, and clinically relevant information Abundant use of pull-out boxes, line artwork, photographs and tables facilitates ease of understanding Contains clinical cases to ensure full comprehension of the topics explored Suitable for physiotherapists, manual therapists, physical therapists, osteopaths, osteopathic physicians and chiropractors, massage therapists, Pilates and yoga teachers & therapists, Tai chi and Feldenkrais practitioners, athletic coaches and voice-coaches.
  • Recombinant gene expression. 2nd ed. 2004, Springer Protocols
    Copy-control tightly regulated expression vectors based on pBAC/oriV / Jadwiga Wild and Waclaw Szybalski -- Cell-free protein synthesis with prokaryotic combined transcription-translation / James R. Swartz, Michael C. Jewett, and Kim A. Woodrow -- Genetic tools for the manipulation of moderately halophilic bacteria of the family Halomonadaceae / Carmen Vargas and Joaquín J. Nieto -- Gene transfer and expression of Recombinant proteins in moderately halophilic bacteria / Amalia S. Afendra ... [et al.] -- Recombinant protein production in antarctic gram-negative bacteria / Angela Duilio, Maria Luisa Tutino, and Gennaro Marino -- Recombinant protein production in yeasts / Danilo Porro and Diethard Mattanovich -- Controlled expression of homologous genes by genomic promoter replacement in the yeast Saccharomyces cerevisiae / Kevin J. Vestrepen and Johan M. Thevelein -- High-throughput expression in microplate format in Saccharomyces cerevisiae / Caterina Holz and Christine Lang -- High-throughput expression in microplate format in Pichia pastoris / Mewes Böttner and Christine Lang -- Multiple gene expression by chromosomal integration and CRE-loxP-mediated marker recycling in Saccharomyces cerevisiae / Björn Johansson and Bärbel Hahn-Hägerdal --Flp-mediated integration of expression cassettes into FRT-tagged chromosomal loci in mammalian cells / Dagmar Wirth and Hansjörg Hauser -- Generation of high-recombinant protein-producing Chinese hamster ovary (CHO) cells / Jean-Louis Goergen and Lucía Monaco -- Preparation of recombinant proteins in milk / Louis-Marie Houdebine.Host cell compatibility in protein expression / James J. Greene -- Production of Recombinant proteins: challenges and solutions / Laura A. Palomares, Sandino Estrada-Moncada and Octavio T. Ramírez -- Folding promoting agents in Recombinant protein production / Beatrix Fahnert -- Back to basics: pBR322 and protein expression systems in e. coli / Paulina Balbás and Francisco Bolívar -- alpha-complementation enabled T7 expression vectors and their use for the expression of recombinant polypeptides for protein transduction experiments / Mikhail F. Alexeyev ... [et al.] -- Expression of recombinant alkaline phosphatase conjugates in Escherichia coli / Jean-Claude Boulain and Frédéric Ducancel -- Overexpression of chromosomal genes in Escherichia coli / Fernando Valle and Noemí Flores -- Chromosomal expression of foreign and native genes from regulatable promoters in Escherichia coli / Lu Zhou, Ke Zhang, and Barry L. Wanner -- Plasmid vectors for marker-free chromosomal insertion of genetic material in Escherichai coli / Sylvie Le Borgne, Francisco Bolívar, and Guillermo Gosset -- Copy-control pBAC/oriV vectors for genomic cloning / Jadwiga Wild and Waclaw Szybalski --Three decades of fungal transformation: key concepts and applications / Vianey Olmedo-Monfil, Carlos Cortés-Penagos, and Alfredo Herrera-Estrella -- Three decades of fungal transformation: novel technologies / Sergio Casas-Flores, Teresa Rosales-Saavedra, and Alfredo Herrera-Estrella -- Gene transfer and expression in plants / Argelia Lorence and Robert Verpoorte -- Production of Recombinant proteins by hairy roots cultured in plastic sleeve bioreactors / Fabricio Medina-Bolívar and Carole Cramer -- Engineering the chloroplasts genome for hyperexpression of human therapeutic proteins and vaccine antigens / Shashi Kumar and Henry Daniell -- New selection marker for plant transformation / Barbara Leyman ... [et al.] -- Enhancer detection and gene trapping as tools for functional genomics in plants / Gerardo Acosta-García, Daphné Autran, and Jean-Philippe Vielle-Calzada -- Gene transfer and expression in mammalian cell lines and transgenic animals / Félix Recillas-Targa -- Sustained heterologous transgene expression in mammalian and avian cell lines / Héctor Rincón-Arano and Félix Recillas-Targa -- Inducible gene expression in mammalian cells and mice / Wilfried Webber and Martin Fussenegger --
  • Recombinant proteins from plants 2009, Springer Protocols
    From Neanderthal to nanobiotech : from plant potions to pharming with plant factories / Christophe Sourrouille ... [et al.] -- Cowpea mosaic virus-based systems for the expression of antigens and antibodies in plants / Frank Sainsbury, Li Liu, and George P. Lomonossoff -- Transient expression of antibodies in plants using syringe agroinfiltration / Marc-André D'Aoust ... [et al.] -- Rapid system for evaluating bioproduction capacity of complex pharmaceutical proteins in plants / Giuliana Medrano ... [et al.] -- Production and localization of recombinant pharmaceuticals in transgenic seeds / Thomas Rademacher, Elsa Arcalis, and Eva Stoger -- Production of antibody fragments in Arabidopsis seeds / Bart Van Droogenbroeck, Kirsten De Wilde, and Ann Depicker -- Production of plantibodies in Nicotiana plants / Marta Ayala ... [et al.] -- Physcomitrella patens : a non-vascular plant for recombinant protein production / David Liénard and Fabien Nogué -- Production of recombinant proteins in suspension-cultured plant cells / Carole Plasson ... [et al.] -- Chloroplast-derived vaccine antigens and biopharmaceuticals : protocols for expression, purification, or oral delivery and functional evaluation / N. Dolendro Singh, Yi Ding, and Henry Daniell -- Protein body induction : a new tool to produce and recover recombinant proteins in plants / Margarita Torrent, Imma Llop-Tous, and M. Dolors Ludevid -- A case study for plant-made pharmaceuticals comparing different plant expression and production systems / Guy Vancanneyt ... [et al.] -- Glycosylation of antibody therapeutics : optimisation for purpose / Roy Jefferis -- N-glycosylation of plant recombinant pharmaceuticals / Muriel Bardor ... [et al.] -- Companion protease inhibitors to protect recombinant proteins in transgenic plant extracts / Meriem Benchabane ... [et al.] -- Strategies for improving vaccine antigens expression in transgenic plants : fusion to carrier sequences / Jose M. Escribano and Daniel M. Perez-Filgueira -- Immunomodulation of plant function by in vitro selected single-chain Fv intrabodies / Manfred Gahrtz and Udo Conrad -- On-chip detection of low-molecular-weight recombinant proteins in plant crude extracts by SELDI-TOF MS / Amine M. Badri ... [et al.] -- Assessing the risk of undesirable immunogenicity/allergenicity of plant-derived therapeutic proteins / Paul D. Chamberlain -- Biosafety, risk assessment, and regulation of plant-made pharmaceuticals / Penelope A.C. Sparrow and Richard M. Twyman.
  • "Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II - reducing chromosome number from the diploid level to a haploid genome, reshuffling the homologous chromosomes by their centromeres, and recombining chromosome arms by crossing-over. In animals, including humans, all this happens during the germ cell formation of eggs and sperm. Due to the reign of meiosis, no child is a true genetic copy of either parent. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. The current book addresses these processes and mechanisms in multicellular eukaryotes, such as Drosophila, Anibidopsis, mice and humans. The pioneering model systems of yeasts, as well as evolutionary aspects, will be addressed in a forthcoming volume."--Jacket.
  • Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II - reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm - in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillar.
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    Classical mendelian genetics -- Genetics and the phage biologists -- The physicist becomes a phage biologist -- To Paris and back -- Teaching and research at Purdue -- Entering the rII region -- Crossing into the fine structure -- Is gene a dirty word? -- The survival of the "gene".
  • Actin filament dynamics using microfluidics -- Bacterial actin-like proteins: purification and characterization of self-assembly properties -- Quantitative analysis of microtubule self-assembly kinetics and tip structure -- Biochemical reconstitution of the WAVE regulatory complex -- Rotational movement of formins evaluated by using single-molecule fluorescence polarization -- Single-molecule studies of actin assembly and disassembly factors -- Assaying microtubule nucleation of the [gamma]-Tubulin ring complex -- Reconstituting dynamic microtubule polymerization regulation by TOG domain proteins -- Generation of differentially modified microtubules using In Vitro enzymatic approaches -- Engineering defined motor ensembles with DNA origami -- Construction and analyses of elastically coupled multiple-motor systems -- Reconstitution of cortical dynein function -- Reconstitution of microtubule-dependent organnelle transport -- Reconstituting the motility of isolated intracellular cargoes -- Reconstitution of contractile actomyosin arrays -- Directed actin assembly and motility -- In Vitro reconstitution of dynamic microtubules interacting with actin filament networks -- Measuring kinetochore-microtubule interaction In Vitro -- Micropattern-guided assembly of overlapping pairs of dynamic microtubules -- WAVE regulatory complex activation -- Dissecting principles governing actin assembly using yeast extracts -- Xenopus egg ctyoplasm with intact actin -- Glycogen-supplemented mitotic cytosol for analyzing xenopus egg microtubule organization -- Spindle assembly on immmobilized chromatin micropatterns.
  • section A. Introduction and general context -- section B. Reconstructing and using the tree of life -- section C. Taxonomy and systematics of species rich groups (case studies).
  • Reconstructive Surgery of the Rectum, Anus and Perineum provides the reader with a didactic discussion of complex problems which require re-operative surgery; including details of preoperative investigation, postoperative follow-up and a detailed operative approach. This comprehensive and detailed text uses a formulated algorithm approach to these complicated cases using operative photographs and composite explanatory line drawings which complement 'how-to' guides in describing the operative technical tips and pitfalls from experienced commentators. Reconstructive Surgery of the Rectum, Anus and Perineum, is written by leading world experts in the field of colorectal surgery and is a valuable and timely resource for colorectal surgeons and colorectal trainees alike. In addition, general surgeons will be interested in the specialist nature of dealing with difficult colorectal complications dealt with in this unique textbook.
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  • Rectal cancer 2010, Springer
  • Rectal cancer 2005, Springer
  • Rectal cancer treatment 2005, Springer
  • This book gives an updated and detailed overview of diagnostic and therapeutic strategies for rectal cancer. Rectal cancer has become an increasing and serious disease in western countries, mainly linked to lifestyle and bad alimentation habits. This specific cancer is not only a threat to the lifespan of patients, but also has a heavy impact on quality of life, due to its implications in the fecal, urinary and sexual functions. Recent guidelines of prevention and early diagnosis, as well as current and future diagnostic and staging work-up, are here presented in a clear and convincing way, linking each topic to the therapeutic options arising from the staging and including a chapter on the molecular evaluation of the tumor. To complete the multifaceted approach to this particular pathology, a large part is devoted to the in-hospital care of rectal cancer patients, beginning from the fast-track procedures and the enhanced recovery systems, up to the in-depth description of the available of surgical techniques, including salvage situations, accidents, complications, and their treatment. A final chapter will be dedicated to the follow-up policy and its advantages.
  • Rectal prolapse 2008, Springer
  • Recurrent hernia 2007, Springer
  • Red blood cell aggregation 2012, CRCnetBASE
  • Red book online Silverchair, Latest ed. only
    Red Book Online is the online home of the Report of the AAP Committee on Infectious Diseases. Offering instant Web-based access, Includes complete text of the Red Book, plus the complete visual library of images from the Visual Red Book on CD-ROM and more.
  • Print Material
    A shocking tour through a macabre global underworld where organs, bones, and live people are bought and sold on the red market. Investigative journalist Scott Carney has spent five years tracing the lucrative and deeply secretive trade in human bodies and body parts. The Red Market reveals the rise, fall, and resurgence of this multibillion-dollar underground trade through history, from early medical study and modern universities to poverty-ravaged Eurasian villages and high-tech Western labs; from body snatchers and surrogate mothers to skeleton dealers and the poor who sell body parts to survive. While local and international law enforcement have cracked down on the market, advances in science have increased the demand for human tissue--ligaments, kidneys, even rented space in women's wombs--leaving little room to consider the ethical dilemmas inherent in the flesh-and-blood trade--From publisher description.
  • Print Material
    What are disabilities? -- Why focus on children with disabilities? -- What are the challenges in delivering health care to children with disabilities? -- Inclusion -- Contribution -- Health -- Focusing health care on function -- Comprehensive integrated care plans -- Family- and person-centered care -- Care coordination / with Alexis Hansen -- Changing professional education -- Research / with Nathan J. Blum -- Public policy.
  • Reactive oxygen species in normal and tumor stem cells / Daohong Zhou, Lijian Shao and Douglas R. Spitz -- Emerging regulatory paradigms in glutathione metabolism / Yilin Liu, Annastasia S. Hyde, Melanie A. Simpson, and Joseph J. Barycki -- Gamma-glutamyl transpeptidase: redox regulation and drug resistance / Marie H. Hanigan -- Pleiotropic functions of glutathione S-transferase P / Jie Zhang, Christina Grek, Zhi-Wei Ye, Yefim Manevich, Kenneth D. Tew and Danyelle M. Townsend -- A comparison of reversible versus irreversible protein glutathionylation / Danyelle M. Townsend, Volodymyr I. Lushchak and Arthur J. L. Cooper -- Glutathione transferases in the bioactivation of azathioprine / Olof Modén and Bengt Mannervik -- Thioredoxin and hematological malignancies / Ningfei An and Yubin Kang -- Role of the Keap1-Nrf2 pathway in cancer / Hanna M Leinonen, Emilia Kansanen, Petri Pölönen, Merja Heinäniemi and Anna-Liisa Levonen.
  • Fulltext (pt. B) ScienceDirect
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  • Redox-mediated signal transduction 2008, Springer Protocols
    The role of redox in signal transduction / John T. Hancock -- The measurement of nitric oxide and its metabolites in biological samples by ozone-based chemiluminescence / Andrew G. Pinder ... [et al.] -- Detection and measurement of reactive oxygen intermediates in mitocondria and cells / Matthew Whiteman ... [et al.] -- Redox-sensitive green fluorescent protein : probes for dynamic intracellular redox responses : a review / Mark B. Cannon and S. James Remington -- Measuring redox changes in vivo in leaves : prospects and technical challenges / Philip M. Mullineaux and Tracy Lawson -- Imaging of intracellular hydrogen peroxide production with hyper upon stimulation of hela cells with Egf / Kseniya N. Markvicheva ... [et al.] -- Tools to investigate ROS sensitive signalling proteins / Radhika Desikan ... [et al.] -- Methods for preparing crystals of reversibly oxidized proteins : crystallization of protein tyrosine phophatase 1b as an example / Annette Salmeen and David Barford -- Methods for the study of redox-mediated changes in p53 structure and function / Kristine Mann -- Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chain aminotransferase / Susan M. Hutson ... [et al.] -- Detection of carbonylated proteins in 2-D SDS page separations / Rukhsana Sultana ... [et al.] -- Analysis of global and specific changes in the disulfide proteome using redox 2D-PAGE / Robert C. Cumming -- Protein-thiol oxidation from single proteins to proteome-wide analyses / Natacha Le Moan, Frédérique Tacnet, and Michel B. Toledano -- Analysis of redox relationships in the plant cell cycle : determinations of ascorbate, glutathione, and poly (ADPribose) polymerase (PARP) in plant cell cultures / Christine H. Foyer ... [et al.] -- Generation and detection of S-nitrosothiols / Christian Lindermayr, Simone Sell, and Jörg Durner.
  • This book describes the techniques, strategies, and drugs that have been demonstrated by well-documented randomized trials to influence survival in the perioperative setting. It takes into consideration all types of adult surgery and will be relevant to the evaluation of any patient undergoing an operative procedure. Each chapter focuses on a specific procedure, device, or drug. The scope is accordingly wide, with coverage of topics as diverse as chlorhexidine oral rinse, clonidine therapy, insulin infusion, intra-aortic balloon pump support, leukodepletion, neuraxial anesthesia, and noninvasive respiratory support, to name but a few. In addition, the risks and benefits of using a web-based consensus process (as in this book) to identify effective means of reducing perioperative mortality are discussed. The clear text is supported by "how to do" sections and "key points" boxes that provide easily accessible practical information. Written by acknowledged international experts, Reducing Mortality in the Perioperative Period will be of interest for a wide variety of specialists, including surgeons, cardiologists, anesthesiologists, and intensivists.
  • Reducing salt in foods 2007, CRCnetBASE
    pt. 1. Dietary salt, health and the consumer -- pt. 2. Strategies for salt reduction in food products -- pt. 3. Reducing salt in particular foods.
  • Toxicity testing is used to assess the safety or hazards presented by substances such as industrial chemicals, consumer products, and pharmaceuticals. At present, many methods involve laboratory animals. Alternative procedures, some involving human cell-based technologies, are now being developed which reduce, refine, or replace animal usage and minimize the pain and distress caused. These new tests must protect public health and the environment at least as well as currently accepted methods. This book describes the ever-expanding "toolbox" of methods available to assess toxicity. Such techniques often result from our growing understanding of the biochemical and cellular pathways that mediate toxicity mechanisms. This permits evaluations of information generated from several sources to generate a "weight of evidence". By combining in silico, in vitro, and ex vivo methods with technologies that rely on biochemical- and cell-based in vitro assays, toxicologists are developing mechanistically based alternatives to live animal experimentation. This text also explores the complexities associated with adequate validation, and the assessment of test reliability and relevance. It provides an essential reference source for postgraduates, academics and industrialists working in this rapidly changing area.
  • Reelin glycoprotein 2008, Springer
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  • Part 1.Confocal Reflectance Microscopy - the Essentials --The Confocal Story --How Reflectance Confocal Microscopy Works --A Hands-on Guide to Confocal Imaging --Part 2.Normal Skin --Epidermis, Dermis and Epidermal Appendages --Acral Volar Skin, Facial Skin and Mucous Membrane --Part 3.Melanocytic lesions --Semeiology and Pattern Analysis in Melanocytic Lesions --Dermoscopic and Histopathologic Correlations --Part 4.Melanocytic lesions: Nevi --Common Nevi --Atypical/Dysplastic Nevi --Spitz Nevi --In Vivo Confocal Reflectance Microscopy of Congenital Melanocytic Nevi --The Many Faces of Nevi: Blue, "Black" and Recurrent Nevi --Part 5.Melanocytic lesions: Melanoma --Superficial Spreading Melanoma --Melanoma Progression --Nodular Melanoma --Lentigo Maligna --Amelanotic Melanoma --Part 6.Non-melanocytic Skin Lesions --Semiology and Pattern Analysis in Nonmelanocytic Lesions --Dermoscopic and Histopathologic Correlations --Solar Lentigo, Seborrheic Keratosis and Lichen Planus-Like Keratosis --Basal Cell Carcinoma --Actinic Keratosis --Squamous Cell Carcinoma --Cutaneous Lymphoma --Potpourri of Nonmelanocytic Skin Lesions --Part 7.Inflammatory Skin Diseases --The Semiology and Patterns of Inflammatory Skin Conditions --Hyperkeratotic Dermatitis --Spongiotic Dermatitis --Interface Dermatitis --Pigmentary Skin Disorders --Part 8.Monitoring of Skin Lesions and Therapy Control --Follow-up of Nevi --Monitoring of Nonsurgical Treatment of Skin Tumors --Confocal Mosaicing Microscopy in Skin Excisions: Feasibility of Cancer Margin Screening at the Bedside to Guide Mohs Surgery --Reflectance Confocal Microscopy Applications in Cosmetology --Part 9.Future Aspects --Tele-Reflectance Confocal Microscopy --Automated Diagnosis and Reflectance Confocal Microscopy --Experimental Applications and Future Directions --Part 10.Glossary --Reflectance Confocal Microscopy Imaging: A Glossary of Terminology.
  • Refractive lens surgery 2005, Springer
    Ch. 1Crystalline lens as a target for refractive surgery --Ch. 2Refractive lens exchange as a refractive surgery modality --Ch. 3Biometry for refractive lens surgery --Ch. 4Intraocular lens power calculations: correction of defocus --Ch. 5IOL calculations following keratorefractive surgery --Ch. 6Correction of keratometric astigmatism: incisional surgery --Ch. 7STAAR toric IOL --Ch. 8Correction of keratometric astigmatism: AcrySof toric IOL --Ch. 9Wavefront technology of spherical aberration --Ch. 10The Eyeonics Crystalens --Ch. 11Presbyopia - cataract surgery with implantation of the accommodative posterior chamber lens ICU --Ch. 12Synchrony IOL --Ch. 13Sarfarazi elliptical accommodative intraocular lens --Ch. 14AcrySof ReStor pseudo-accommodative IOL --Ch. 15The Tecnis Multifocal IOL --16Blue-light-filtering intraocular lenses --Ch. 17The light-adjustable lens --Ch. 18Injectable polymer --Ch. 19The vision membrane --Ch. 20Bimanual ultrasound phacoemulsification --Ch. 21Low ultrasound microincision cataract surgery --Ch. 22The Infiniti Vision System --Ch. 23The Millenium --Ch. 24The Staar Sonic Wave --Ch. 25AMO Sovereign with WhiteStar Technology --Ch. 26Refractive lens exchange in high myopia: weighing the risks --Ch. 27Conclusion: the future of refractive lens surgery --Subject index.DVD:1.Transition to bimanual phaco --2.Bimanual vertical chop technique #1 --3.Bimanual vertical chop technique #2 --4.VST torn capsule --5.Bimanual post PKP post RK --6.Spinoffs of bimanual technology.
  • Refugee health care 2014, Springer
    "Physicians receive very little training in refugee health. Refugee Health Care is a practical guide providing concise information for busy practitioners. This concise textbook reviews common conditions seen in refugees and some of the recommendations in the book apply to all immigrants. It will be a valuable resource for primary care physicians, psychiatrists, pediatricians, women's health providers and any health care practitioner who treats refugees."--Publisher's website.
  • Regenerating the heart 2011, Springer
    Inducing embryonic stem cells to become cardiomyocytes / Alexander M. Becker, Michael Rubart, and Loren J. Field -- Regenerating function in vivo with myocytes derived from embryonic stem cells / Priya R. Baraniak and Todd C. McDevitt -- Excitation-contraction coupling, functional properties, and autonomic and hormonal regulation in human embryonic stem cell derived cardiomyocytes / Oshra Sedan and Ofer Binah -- Embryonic stem cell derivatives for cardiac therapy : advantages, limitations, and long-term prospects / Michal Weiler-Sagie and Lior Gepstein -- Methods for differentiation of bone-marrow-derived stem cells into myocytes / Shinji Makino and Keiichi Fukuda -- Homing, survival, and paracrine effects of human mesenchymal stem cells / Sergey Doronin -- Bone marrow cell therapy after myocardial infarction : what have we learned from the clinical trials and where are we going? / Kai C. Wollert -- Evidence for the existence of resident cardiac stem cells / Isotta Chimenti ... [et al.] -- Multiple sources for cardiac stem cells and their cardiogenic potential / Antonio Paolo Beltrami, Daniela Cesselli, and Carlo Alberto Beltrami -- Skeletal muscle stem cells in the spotlight : the satellite cell / Zipora Yablonka-Reuveni and Kenneth Day -- Regenerating mechanical function in vivo with skeletal myoblasts / Todd K. Rosengart and Muath Bishawi -- Methods for inducing pluripotency / Raymond L. Page, Christopher Malcuit, and Tanja Dominko -- Inducible pluripotent stem cells for cardiac regeneration / Naama Zeevi-Levin and Joseph Itskovitz-Eldor -- Induced pluripotent cells for myocardial infarction repair / Timothy J. Nelson and Andre Terzic -- Substrates of cardiac reentrant arrhythmias : the possible role of tissue regeneration and replacement / André G. Kléber -- Integration of stem cells into the cardiac syncytium : formation of gap junctions / Peter R. Brink, Ira S. Cohen, and Richard T. Mathias -- Bradyarrhythmia therapies : the creation of biological pacemakers and restoring atrioventricular node function / Richard B. Robinson -- Tachyarrhythmia therapies : approaches to atrial fibrillation and postinfarction ventricular arrhythmias / J. Kevin Donahue and Kenneth R. Laurita -- Long-term prospects for arrhythmia treatment : advantages and limitations of gene and cell therapies / Michael R. Rosen -- Regenerating blood vessels / Tracy A. Gwyther and Marsha W. Rolle -- Regenerating heart valves / Benedikt Weber and Simon P. Hoerstrup -- Tissue engineering strategies for cardiac regeneration / Amandine F.G. Godier-Furnémont ... [et al.] -- Methods of cell delivery for cardiac repair / Sarah Fernandes and Hans Reinecke -- Tracking of stem cells in vivo / Yingli Fu and Dara L. Kraitchman -- Assessing regional mechanical function after stem cell delivery / Jacques P. Guyette and Glenn R. Gaudette.
  • Frontiers of spinal cord and spine repair : experimental approaches for repair of spinal cord injury / Choya Yoon and Mark H. Tuszynski -- Stem cell based strategies for spinal cord injury repair / Alexa Reeves and Hans S. Keirstead -- Strategies for endogenous spinal cord repair : HPMA hydrogel to recruit migrating endogenous stem cells / Araceli Espinosa-Jeffrey ... [et al.] -- Stem cells and spinal cord injury repair / Soheila Karimi-Abdolrezaee and Eftekhar Eftekharpour -- Chronic pain following spinal cord injury / Radi Masri and Asaf Keller -- Repair of radiation damage and radiation injury to the spinal cord / Timothy E. Schultheiss -- Malignancies of the spinal cord / J. Dawn Waters, Encarnacion Maria Navarro Peran, and Joseph Ciacci -- Molecular basis of intervertebral disc degeneration / Dipika Gopal ... [et al.] -- Bioceramics for osteogenesis, molecular and cellular advances / Hande Demirkiran -- Cell-based therapies for spinal fusion / Ronke Olabisi -- Clinical efficacy of stem cell mediated osteogenesis and bioceramics for bone tissue engineering / Josh Neman ... [et al.] -- Progenitor cells : role and usage in bone tissue engineering approaches for spinal fusion / Lonnissa H. Nguyen ... [et al.].
  • Regenerative medicine 2011, Springer
  • 1. Cell Therapy for Neurodegenerative Disorders / Ilyas Singec -- 2. New Prospects for Neural Stem Cell Therapies of Nervous System Diseases Toward the Establishment of Atypical Ectopic Perivascular Stem Cell Niches / Clara Alfaro-Cervello, Chiara Cossetti, Elena Giusto, Matteo Donegà and Stefano Pluchino -- 3. Cultured Limbal Epithelial Stem Cell Therapy for Ocular Surface Diseases / Hannah J. Levis, Julie T. Daniels and Sajjad Ahmad -- 4. Keratinocyte Stem Cells: Biology and Clinical Applications / Carlo Pincelli and Alessandra Marconi -- 5. Cardiac Regeneration with Stem Cells / Beatriz Pelacho, Manuel Mazo, Sheyla Montori, Ana Maria Simon-Yarza, Juan Jose Gavira, Maria J. Blanco-Prieto and Felipe Prósper -- 6. Development of Biological Approaches to Improve Muscle Healing After Injury and Disease / Jonathan D. Proto and Johnny Huard -- 7 Mesenchymal Stem Cells in Bone and Cartilage Regeneration / Mohamadreza Baghaban Eslaminejad, Elham Zomorodian and Fatemeh Bagheri -- 8. Pancreatic Reprogramming / Juan Domínguez-Bendala -- 9. Pancreatic Regeneration in the Face of Diabetes / Zeeshan Ahmad -- 10. Regenerative Therapies for Liver Diseases / Amar Deep Sharma, Ina Rittelmeyer, Tobias Cantz and Michael Ott -- 11. Clinical Studies of Cell Therapy for Liver Cirrhosis / James A. Thomas and Stuart J. Forbes -- 12. Stem Cell Applications for the Treatment of Gastrointestinal System Diseases / Jacobo Trebol Lopez, Tihomir Georgiev-Hristov, Mariano García-Arranz and Damián García-Olmo -- 13. Germ Line Stem Cells: A Promising Alternative Source for Stem-Cell-Based Therapies in Regenerative Medicine / Ellen Goossens and Herman Tournaye -- 14. Cord Blood Stem Cells and Regenerative Medicine / David T. Harris.
  • Principles of regenerative medicine and cell,tissue and organ bioengineering -- Kidney -- Liver -- Heart -- Small bowel -- Endocrine pancreas and islets of langerhans -- Lung -- Composite tissues allotranplantation -- Immunosuppression-free transplantation in the regenerative medicine era.
  • A massive wastage of the global resources -- Placenta as a source of stem cells and as a key organ for fetomaternal tolerance -- Placenta and umbilical cord in traditional Chinese medicine -- Use of umbilical venous blood on assessing the biochemical variations of acid-base, nutritional and metabolic parameters on growth-retarded fetuses, in comparison with gestational control cases: a study -- Umbilical cord blood transfusion and its therapeutic potentialities -- Autologous placental blood transfusion for the therapy of anemic neonates -- Cord blood: a massive waste of a life-saving resource: a perspective on its current and potential uses -- Clinical experience of cord blood autologous transfusion -- Emergency use of human cord blood -- Hemoglobin-based oxygen carriers in trauma care: the US multicenter prehospital trial -- Placental umbilical cord blood as a true blood substitute with an edge -- Implications of feto-maternal cell transfer in normal pregnancy -- Early reports on the prognostic implications and immunotherapeutic potentials of Cd34 rich cord whole blood transfusion in advanced breast cancer with severe anemia -- Anti-inflammatory effects of human cord blood and its potential implications in neurological disorders -- Transforming "waste" into gold: identification of novel stem cells resources with therapeutic potential in neuromuscular disorders -- Human umbilical cord blood cells for stroke -- Placental umbilical cord blood transfusion for stem cell therapy in neurological diseases -- Umbilical cord and its blood: a perspective on its current and potential use in ophthalmology -- Umbilical vein grafts for lower limb revascularization -- Cord blood stem cells in angiogenesis.Endothelial progenitor cells from cord blood: magic bullets against ischemia? -- Therapeutic potential of placental umbilical cord blood in cardiology -- Stem cell therapy for heart failure using cord blood -- Human umbilical cord blood mononuclear cells in the treatment of acute myocardial infarction -- Umbilical cord-derived mesenchymal stem cells -- Cord blood stem cell expansion ex vivo: current status and future strategies -- Embryonic-like stem cells and the importance of human umbilical cord blood for regenerative medicine -- Use of non-hematopoietic stem cells of fetal origin from cord blood, umbilical cord, and placenta in regeneration medicine -- Animal studies of cord blood and regeneration -- Immune privilege of cord blood -- Combination cellular therapy for regenerative medicine: the stem cell niche -- Use of cord blood in regenerative medicine -- Comparisons between related and unrelated cord blood collection and/or banking for transplantation or research: the UK NHS blood and transplant experience -- Donor and collection-related variables affecting product quality in ex utero cord blood banking -- Cord blood as a source of hematopoietic progenitors for transplantation -- Amniotic fluid and placenta stem cells -- Use of amniotic membrane, amniotic fluid, and placental dressing in advanced burn patients -- Clinical use of amniotic fluid in osteoarthritis: a source of cell therapy -- A study and follow-up (1999-2009) of human fetal neuronal tissue transplants at a heterotopic site outside the brain in cases of advanced idiopathic Parkinsonism -- Ethical issues surrounding umbilical cord blood donation and banking.
  • Chapter 1. Glomerulogenesis and De Novo Nephrogenesis in Medaka Fish: An Evolutionary Approach / Hisashi Hashimoto, Yuko Wakamatsu -- Chapter 2. Renal Organogenesis: Growing a Replacement Kidney In Situ from Transplanted Renal Primordia / Marc R. Hammerman -- Chapter 3. Use of Genetic Mouse Models to Study Kidney Regeneration / Akio Kobayashi, Jeremy S. Duffield -- Chapter 4. Endogenous Anti-inflammatory and Proresolving Lipid Mediators in Renal Disease / Charles N. Serhan, Catherine Godson -- Chapter 5. Tissue Protection and Regeneration Aided by Erythropoietin and Erythropoietin-derived Peptides / Danilo Fliser -- Chapter 6. Mast Cells in Kidney Regeneration / Eric Daugas, Walid Beghdadi, Ulrich Blank -- Chapter 7. Role of Macrophages in Renal Injury, Repair and Regeneration / Vincent Lee, Qi Cao, Yiping Wang, David C.H. Harris -- Chapter 8. T-cell Contribution to Injury and Regenerative Processes in Kidney Diseases: Focus on Regulatory T Cells / Hye Ryoun Jang, Hamid Rabb -- Chapter 9. Mesenchymal Stem Cells / Benjamin D. Humphreys, Joseph V. Bonventre -- Chapter 10. Endothelial Progenitor Cells and the Kidney / Matthieu Monge, Anton Jan van Zonneveld, Ton J. Rabelink -- Chapter 11. Potential of the Side Population in Regenerative Nephrology / M.H. Little, G.A. Challen -- Chapter 12. Very Small Embryonic-like Stem Cells and Their Potential Relevance for Kidney Homeostasis / Dong-Myung Shin, Rui Liu, Przemyslaw Nowacki, Janina Ratajczak, Magda Kucia, Mariusz Z. Ratajczak -- Chapter 13. Induced Pluripotent Stem Cells / Kenji Osafune, Shinya Yamanaka -- Chapter 14. Methods of Isolation and Culture of Adult Stem Cells / Lindolfo da Silva Meirelles, Nance Beyer Nardi -- Chapter 15. Stem Cell Niche in the Kidney / Laura Lasagni, Elena Lazzeri, Paola Romagnani -- Chapter 16. Bioartificial Stem Cell Niches: Engineering a Regenerative Microenvironment / Glenn D. Prestwich, Tammer Ghaly, Philip Brudnicki, Brian Ratliff, Michael S. Goligorsky -- Chapter 17. Imaging of Transplanted and Native Stem Cells / Xiang-Yang Zhu, Martin Rodriguez-Porcel, Lilach O. Lerman -- Chapter 18. Stem Cell Injury and Premature Senescence / Michael S. Goligorsky -- Chapter 19. Regeneration and Aging: Regulation by Sirtuins and the NAD+ Salvage Pathway / Nica M. Borradaile, Alanna Watson, J. Geoffrey Pickering -- Chapter 20. Bone Marrow Mesenchymal Stem Cells in Organ Repair and Strategies to Optimize their Efficacy / Christodoulos Xinaris, Barbara Imberti, Giuseppe Remuzzi, Marina Morigi -- Chapter 21. Treatment of Acute Kidney Injury with Allogeneic Mesenchymal Stem Cells: Preclinical and Initial Clinical Data / Florian E. Tögel, Christof Westenfelder -- Chapter 22. Clinical Trials in Renal Regenerative Medicine / Maarten B. Rookmaaker, Jaap A. Joles, Marianne C. Verhaar -- Chapter 23. Potential Risks of Stem Cell Therapies / Uta Kunter, Jürgen Floege -- Chapter 24. Tissue Engineering in Urology / Anthony Atala -- Chapter 25. Ethics in Regenerative Medicine / Svetlana Gavrilov, Donald W. Landry -- Chapter 26. Stem Cell Banking / Vicente Mirabet, Pilar Solves.
  • Regenerative pharmacology 2013, Cambridge
    "Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues, and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental, and molecular biology; chemical and material sciences (i.e., nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. The goal of this book is to draw attention to the critical role that the pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. This is the first state-of-the-art book in this rapidly evolving field of research"--Provided by publisher.
  • Print Material
    From bioplastics to H. sapiens 2.0 -- -3,800 Myr, Late Hadean : at the inorganic/organic interface -- -3,500 Myr, Archean : reading the most ancient texts and the future of living software -- -500 Myr, Cambrian : the mirror world and the explosion of diversity ; How fast can evolution go and how diverse can it be? -- -360 Myr, Carboniferous : "the best substitute for petroleum is petroleum" -- -60 Myr, Paleocene : emergence of mammalian immune system ; Solving the health care crisis through genome engineering -- -30,000 Yr, Pleistocene Park : engineering extinct genomes -- -10,000 Yr, Neolithic : industrial revolutions ; The agricultural revolution and synthetic genomics ; The BioFab Manifesto -- -100 Yr, Anthropocene : the third industrial revolution ; iGEM -- -1 Yr, Holocene : from personal genomes to immortal human components -- Epigenetic epilogue. +1 Yr, the end of the beginning, transhumanism, and the Panspermia Era : societal risks and countermeasures.
  • Regional cancer therapy 2007, Springer
  • Various applications in the field of pulmonary image analysis require a registration of CT images of the lung. For example, a registration-based estimation of the breathing motion is employed to increase the accuracy of dose distribution in radiotherapy. Alexander Schmidt-Richberg develops methods to explicitly model morphological and physiological knowledge about respiration in algorithms for the registration of thoracic CT images. The author focusses on two lung-specific issues: on the one hand, the alignment of the interlobular fissures and on the other hand, the estimation of sliding motion at the lung boundaries. He shows that by explicitly considering these aspects based on a segmentation of the respective structure, registration accuracy can be significantly improved.
  • Introduction -- Exploratory and descriptive methods -- Basic statistical methods -- Linear regression -- Predictor selection -- Logistic regression -- Survival analysis -- Repeated measures analysis -- Generalized linear models -- Complex surveys -- Summary.
  • Regression modeling 2009, CRCnetBASE
    Review of fundamental of statistics -- Bivariate linear regression and correlation -- Misspecified disturbance terms -- Nonparametric regression -- Logistic regression -- Bayesian regression -- Robust regression -- Fuzzy regression -- Random coefficients regression -- L1 and q-Quantile regression -- Regression in a spatial domain -- Multiple regression -- Normal correlation models -- Ridge regression -- Indicator variables -- Polynomial model estimation -- Semiparametric regression -- Nonlinear regression -- Issues in time series modeling and estimation.
  • Time series following generalized linear models -- Regression models for binary time series -- Regression models for categorical time series -- Regression models for count time series -- Other models and alternative approaches -- State space models -- Prediction and interpolation -- Appendix: Elements of stationary processes.
  • Examining the molecular mechanism of Bcl-2 family proteins at membranes by fluorescence spectroscopy -- Photoreactive stapled peptides to identify and characterize BCL-2 family interaction sites by mass spectrometry -- The structural biology of BH3-only proteins -- How to analyze mitochondrial morphology in healthy cells and apoptotic cells in Caenorhabditis elegans -- Apoptosis initiation through the cell-extrinsic pathway -- Using RNAi screening technologies to interrogate the extrinsic apoptosis pathway -- Caspase enzymology and activation mechanisms -- Turning on caspases with genetics and small molecules -- A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases -- Measuring caspase activity in vivo -- Single-molecule sensing of caspase activation in live cells via plasmon coupling nanotechnology -- In vivo monitoring of caspase activation using a fluorescence resonance energy transfer-based fluorescent probe -- Global analysis of cullular proteolysis by selective enzymatic labelling of protein N-termini -- Complementary methods for the indentification of substrates of proteolysis -- Phospholipid scrambling on the plasma membrane -- Studying apoptosis in the zebrafish.
  • AAA+ proteolytic machines --Machines of destruction: AAA+ proteases and the adaptors that control them /Eyal Gur, Ralf Ottofueling, David A. Dougan --The Lon AAA+ protease /Eyal Gur --FtsH protease-mediated regulation of various cellular functions /Takashi Okuno, Teru Ogura -- Regulatory proteolysis in bacteria --General and regulatory proteolysis in Bacillus subtilis /Nöel Molière, Kürşad Turgay --Proteolytic regulation of stress response pathways in Escherichia coli /Dimce Micevski, David A. Dougan -- Regulated proteolysis: control of the Escherichia coli [sigma]E-dependent cell envelope stress response /Sarah E. Barchinger, Sarah E. Ades --Bacterial proteases and virulence /Dorte Frees, Lone Brøndsted, Hanne Ingmer -- Regulated proteolysis in yeast --Roles of Cdc48 in regulated protein degradation in yeast /Alexander Buchberger --The Role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis and activity control /Wolfgang Voos, Linda A. Ward, Kaye N. Truscott -- Ubiquitin-like protein modification and protein degradation in microorganisms --The pup-proteasome system of mycobacterium tuberculosis /Marie I. Samanovic, Huilin Li, K. Heran Darwin --Archaeal proteasomes and sampylation /Julie A. Maupin-Furlow.
  • Print Material
  • Micro mining : computational approaches to miRNA discovery / Adam Grundhoff -- Animal microRNA gene prediction / Ola Snv?e and Pa<U+030a>l St?rom -- A suite of resources for the study of miRNA ontology and function / Praveen Sethupathy, Molly Megraw, and Artemis G. Hatzigeorgiou -- Regulation of translation and mRNA stability by Hfq-binding small RNAs in Escherichia coli / Hiroji Aiba -- Mechanisms by which microRNAs regulate gene expression in animal cells / Yang Yu and Timothy W. Nilsen -- The microRNAs of C. elegans / Mona J. Nolde and Frank J. Slack -- Isolation and characterization of small RNAs in C. elegans / Chisato Ushida and Yusuke Hokii -- MicroRNA tales in fly development / Utpal Bhadra ... [et al.] -- RNA interference and miRNAs in zebrafish / Alex S. Flynt, Elizabeth J. Thatcher, and James G. Patton -- Biogenesis and function of plant microRNAs / Zoltan Havelda -- Endogenous small RNA pathways in Arabidopsis / Manu Agarwal, Julien Curaba, and Xuemei Chen.How to assay miRNA expression : a technology guide / Mirco Castoldi, Vladimir Benes, and Martina U. Muckenthaler -- Methods to quantify microRNA gene expression / Lori A. Neely -- Regulation of alternative splicing by microRNAs / Rajesh K. Gaur -- Recent progress in polymerase II-mediated intronic microRNA expression systems / Shi-Lung Lin and Shao-Yao Ying -- MicroRNA-based RNA polymerase II expression vectors for RNA interference in mammalian cells / Anne B. Vojtek ... [et al.] -- Transgenic RNAi : a fast and low-cost approach to reverse genetics in mammals / Linghua Qiu and Zuoshang Xu -- Symphony of AIDS : an miRNA-based therapy / Yoichi R. Fujii -- MicroRNAs and cancer : connecting the dots / Sumedha D. Jayasena -- Mammalian transcriptional gene silencing by small RNAs / Daniel H. Kim and John J. Rossi -- Regulation of gene expression by RNA mediated transcriptional gene silencing / Kevin V. Morris.
  • Regulation of microRNAs 2011, Springer
    MicroRNA biogenesis and function : an overview / Rene F. Ketting -- Regulation of pri-miRNA processing through Smads / Akiko Hata and Brandi N. Davis -- Stimulation of pri-miR-18a processing by hnRNP A1 / Gracjan Michlewski, Sonia Guil, and Javier F. Cáceres -- KSRP promotes the maturation of a group of miRNA precursors / Michele Trabucchi ... [et al.] -- Hormonal repression of miRNA biosynthesis through a nuclear steroid hormone receptor / Sally Fujiyama-Nakamura, Kaoru Yamagata, and Shigeaki Kato -- Autoregulatory mechanisms controlling the microprocessor / Robinson Triboulet and Richard I. Gregory -- Regulation of pre-miRNA processing / Nicolas J. Lehrbach and Eric A. Miska -- The effect of RNA editing and ADARs on miRNA biogenesis and function / Bret S.E. Heale, Liam P. Keegan, and Mary A. O'Connell -- MiRNAs need a trim regulation of miRNA activity by trim-NHL proteins / F. Gregory Wulczyn ... [et al.] -- Properties of the regulatory RNA-binding protein HuR and its role in controlling miRNA repression / Nicole-Claudia Meisner and Witold Filipowicz -- Turnover of mature miRNAs and siRNAs in plants and algae / Heriberto Cerutti and Fadia Ibrahim -- MicroRNases and the regulated degradation of mature animal miRNAs / Helge Grosshans and Saibal Chatterjee.
  • Regulators of G-protein signaling. Part A-B pt. A-B, 2004., ScienceDirect
    pt. B, 2004 ScienceDirect
  • Regulatory genome 2006, ScienceDirect
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  • Regulatory RNAs 2006, Cold Spring Harb Lab Press
    Mechanism and biology of RNAi -- Genome-wide approaches -- Small RNAs in development -- Telomeres and cancer -- End regulation of transcripts -- RNPs and RNA editing -- Biology of short RNAs -- Control of gene expression by noncoding RNAs -- Heterochromatin -- Quality control, messenger RNA turnover, and translational control.
  • Regulatory RNAs 2012, Springer
    pt. 1. Basics -- pt. 2. Methods -- pt. 3. Applications.
  • This book provides a comprehensive and up-to-date collection of review articles focusing on RNA-mediated regulation in prokaryotes. The various modes of action include the direct interaction with proteins, direct sensing of metabolites or of physical parameters, and the interaction with RNAs to stimulate or prevent binding of ribosomes or to stimulate degradation. Written by leading experts in the field, the book covers small RNA functions, RNA thermometers, riboswitches, the diversity of small RNA-guided CRISPR-Cas defense systems and selected RNA chaperons in both prokaryotic domains, bacteria and archaea. Recent advances towards the computational identification of regulatory RNAs and their targets are included and particular attention is paid to small RNA in pathogenic bacteria. This volume is the only one exclusively covering regulatory RNAs in the prokaryotic domains to date, making it essential literature for anyone interested in RNA function and gene regulation and a valuable resource for teaching these concepts.
  • "Designed in a concise, easy-to-read style for a wide variety of medical occupations, the Rehab Clinical Pocket Guide is the ideal, handy reference for rehabilitation professionals and other health providers. Divided into four sections that cover inpatient care, clinical strategies, outpatient care, and additional diagnostics and therapeutics, this is the first book of its kind to contain all of the relevant clinical information needed on the rehabilitation unit, including specific admission order sets and topics such as medication dosing, consultant recommendations, specific rehabilitation goals and treatments, and even billing details for various diagnoses. The Rehab Clinical Pocket Guide offers all the clinical material needed to properly treat patients and excel in the field of physical medicine and rehabilitation and will prove an indispensable resource for medical students, residents, physicians, therapists and nutritionists."--P. 4 of cover."
  • Rehabilitation outcome measures 2010, ScienceDirect
    Outcome measurement and practice -- International classification of functioning, disability and health (ICF) -- How to choose an outcome measure -- Reliability : error in measurement -- Validity -- Measuring change -- Measuring mobility -- Measuring physical activity -- Measuring fatigue -- Measuring neurological conditions and rehabilitation -- Evaluating satisfaction.
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    Americans with Disabilities Act and accessibility issues (including wheelchair information) -- Musculoskeletal anatomy, orthopedics, and orthopedic therapy -- Neuroanatomy, neurology, and neurologic therapy -- Pulmonary anatomy and pulmonary therapy -- Vascular anatomy, cardiology, and cardiac rehabilitation -- Pediatrics -- Geriatrics -- Measurement, assessment, and outcomes -- Kinesiology and gait -- Prosthetics and orthotics -- Psychology and psychiatry -- Electromagnetic, thermal modalities, and electrotherapy -- Massage and soft tissue techniques -- General medicine (including oncology and AIDS) -- Pharmacology -- Burns -- Reference tables and conversion charts -- Translations : useful expressions.
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  • Reimagining global health 2013, Click LINK above for location/circulation status.
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    "Bringing together the experience, perspective and expertise of Paul Farmer, Jim Yong Kim, and Arthur Kleinman, Reimagining Global Health provides an original, compelling introduction to the field of global health. Drawn from a Harvard course developed by their student Matthew Basilico, this work provides an accessible and engaging framework for the study of global health. Insisting on an approach that is historically deep and geographically broad, the authors underline the importance of a transdisciplinary approach, and offer a highly readable distillation of several historical and ethnographic perspectives of contemporary global health problems.The case studies presented throughout Reimagining Global Health bring together ethnographic, theoretical, and historical perspectives into a wholly new and exciting investigation of global health. The interdisciplinary approach outlined in this text should prove useful not only in schools of public health, nursing, and medicine, but also in undergraduate and graduate classes in anthropology, sociology, political economy, and history, among others"--Provided by publisher.
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    Analytic framework / Lu Ann Aday -- Fundamental determinants of population health / Kathryn M. Cardarelli ... [et al.] -- Sustainable development / Sondip K. Mathur, Carl S. Hacker, Lu Ann Aday -- Human development / Barbara J. Low ... [et al.] -- Economic development / Luisa Franzini ... [et al.] -- Community development and public health / Cynthia Warrick ... [et al.] -- Toward a healthy (re)public / Lu Ann Aday ... [et al.].
  • Relational competence the set of traits that allow people to interact with each other effectively enjoys a long history of being recorded, studied, and analyzed. Accordingly, Relational Competence Theory (RCT) complements theories that treat individuals' personality and functioning individually by placing the individual into full family and social context. The ambitious volume Relational Competence Theory: Research and Mental Health Applications opens out the RCT literature with emphasis on its applicability to interventions, and updates the state of research on RCT, examining what is robust and verifiable both in the lab and the clinic. The authors begin with the conceptual and empirical bases for the theory, and sixteen models demonstrate the range of RCT concerns and their clinical relevance, including: socialization settings for relational competence, the ability to control and regulate the self, relationship styles, intimacy and negotiation, the use of practice exercises in prevention and treatment of pathology, appendices featuring the Relational Answers Questionnaire and other helpful tools. Relational Competence Theory both challenges and confirms much of what we know about the range of human relationships, and is important reading for researchers, scholars, and students in personality and social psychology, psychotherapy, and couple and family counseling.
  • Relaxin and related peptides Lane Catalog record
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    Relaxin and related peptides in male reproduction / Alexander I. Agoulnik -- The vascular actions of relaxin / Arundhathi Jeyabalan ... [et al.] -- The effects of relaxin on extracellular matrix remodeling in health and fibrotic disease / Chrishan S. Samuel, Edna D. Lekgabe, and Ishanee Mookerjee -- Relaxin-like ligand receptor systems: are autocrine/paracrine effectors in tumor cells and modulate cancer: progression and tissue invasiveness / Thomas Klonisch ... [et al.] -- Relaxin family peptide and receptor systems in brain: insights from recent anatomical and functional studies / Sherie Ma and Andrew L. Gundlach.The evolution of the relaxin peptide family and their receptors / Tracey N. Wilkinson and Ross A.D. Bathgate -- Relaxin, the relaxin-like factor and their receptors / Christian Schwabe and Erika E. Büllesbach -- Diverse signalling mechanisms used by relaxin in natural cells and tissues: the evolution of a "neohormone" / Richard Ivell, Kee Heng, and Ravinder Anand-Ivell -- Relaxin physiology in the female reproductive tract during pregnancy / Laura J. Parry and Lenka A. Vodstrcil --
  • Introduction -- Adaptation and contraction theory for the synchronization of complex neural networks -- Temporal coding is not only about cooperation, it is also about competition -- Using non-oscillatory dynamics to disambiguate pattern mixtures -- Functional constraints on network topology via generalized sparse -- Evolution of time in neural networks, from the present to the past, and forward to the future -- Synchronization of coupled pulse-type hardware neuron models for CPG model -- A univesal abstract-time platform for real-time neural networks -- Solving complex control tasks via simple rule(s), using chaotic dynamics in a recurrent neural network model -- Time scale analysis of neuronal ensemble data used to feed neural network models -- Simultaneous EEG-fMRI, integrating spatial and temporal resolution -- Erratum to: Time scale analysis of neuronal ensemble data used to feed neural network models.
  • Reliability in cognitive neuroscience 2013, Click LINK above for location/circulation status.
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    "Cognitive neuroscientists increasingly claim that brain images generated by new brain imaging technologies reflect, correlate, or represent cognitive processes. In this book, William Uttal warns against these claims, arguing that, despite its utility in anatomic and physiological applications, brain imaging research has not provided consistent evidence for correlation with cognition. Uttal bases his argument on an extensive review of the empirical literature, pointing to variability in data not only among subjects within individual experiments but also in the new meta-analytical approach that pools data from different experiments. This inconsistency of results, he argues, has profound implications for the field, suggesting that cognitive neuroscientists have not yet proven their interpretations of the relation between brain activity captured by macroscopic imaging techniques and cognitive processes; what may have appeared to be correlations may have only been illusions of association. He supports the view that the true correlates are located at a much more microscopic level of analysis: the networks of neurons that make up the brain." -- [Publisher-supplied data]
  • Basic mathematical concepts -- Introduction to reliability technology, human error, and quality -- Medical device safety and quality assurance -- Medical device software quality assurance and risk assessment -- Medical device maintenance and sources for obtaining medical device-related failure data -- Human error in health care -- Health care human error reporting systems and models for predicting human reliability and error in health care -- Patient safety -- Introduction to quality in health care -- Quality methods for use in health care.
  • 1. Introduction -- 2. Pain as a Public Health Challenge -- 3. Care of People with Pain -- 4. Education Challenges -- 5. Research Challenges -- 6. A Blueprint for Transforming Pain Prevention, Care, Education, and Research -- Glossary -- A. Data Sources and Methods -- B. Summary of Written Public Testimony -- C. The Economic Costs of Pain in the United States -- D. Committee and Staff Biographies.
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  • Renal cancer Springer Protocols
  • Epidemiology, Screening, and Clinical Staging / Michael J. Lipsky, Christopher M. Deibert -- Molecular Biology and Genetics / Jeff Klomp, Karl Dykema, Bin Tean Teh, Kyle Furge -- Familial and Hereditary Syndromes / Brian Shuch, Peter Pinto -- Pathology of Renal Cell Carcinoma / Fang-Ming Deng, Jonathan Melamed, Ming Zhou -- Imaging of Renal Cancer / Jalil Afnan, Christoph Wald -- Molecular Imaging for Renal Cell Carcinoma / Jian Q. Yu, Yamin Dou -- History of Renal Surgery for Cancer / Kamal Nagpal, Karim Hamawy -- Natural History, Role of Biopsy, and Active Surveillance of Renal Masses / Anthony T. Corcoran, Marc C. Smaldone, Robert G. Uzzo -- Interventional Radiology and Angioinfarction: Transcatheter Embolization of Renal Tumors / Sebastian Flacke, Shams Iqbal -- Unified Approaches to Surgery and Systemic Therapy for Renal Cell Carcinoma / Patrick A. Kenney, Christopher G. Wood -- Rationale for Partial Nephrectomy / Nicholas Donin, William Huang -- Objectifying Complexity of Kidney Cancers: Relationships of Tumor Anatomy and Outcomes / Serge Ginzburg, Alexander Kutikov, Robert G. Uzzo -- Open Partial Nephrectomy / Patrick A. Kenney, Matthew F. Wszolek, John A. Libertino -- Minimally Invasive Partial Nephrectomy and Ablative Procedures for Small Renal Masses / Casey G. Kowalik, David Canes, Ali Moinzadeh -- Surgery for Renal Cell Carcinoma with Thrombus Extension into the Vena Cava / Chad Wotkowicz, John A. Libertino -- Role of Lymphadenectomy / Prof. Dr. Hein Van Poppel -- Postoperative Surveillance Protocols for Renal Cell Carcinoma / Megan M. Merrill., Jose A. Karam -- Role of Surgery in Locally Recurrent and Metastatic Renal Cancer / Paul Russo -- Outcomes: Prognostic Factors, Models, and Algorithms / Brandon K. Isariyawongse, Michael W. Kattan -- Adjuvant Systemic Therapy, Immunotherapy, and Targeted Treatment / Linda Cerbone, Cora N. Sternberg -- Role for Radiation Therapy in Renal Cancer / Andrea McKee, Arul Mahadevan, Timothy Walsh -- Surgical Management for Transitional Cell Carcinoma of the Upper Tract / Jason R. Gee -- Management of Non-clear Cell Renal Cell Carcinoma / Henry J. Conter, Jose A. Karam, Nizar M. Tannir.
  • Renal cell cancer 2008, Springer
  • Part 1.Localized Disease --Etiology of Renal Cell Carcinoma: Incidence, Demographics, and Environmental Factors /Frédéric D. Birkhäuser, Nils Kroeger and Allan J. Pantuck --Pathology of Renal Cell Carcinoma /Ming Zhou and Huiying He --Familial Renal Cell Carcinoma /Simon P. Kim and Bradley C. Leibovich --Imaging of Renal Cell Carcinoma /Andrei S. Purysko, Erick M. Remer and Brian R. Herts --Prognostic Factors for Localized Renal Cell Carcinoma /Brian R. Lane --Part 2.Management of Localized RCC --Assessment of Oncologic Risk for Clinical Stage T1 Renal Tumors and the Emerging Role of Renal Mass Biopsy /Matthew N. Simmons and Steven C. Campbell --Radical Nephrectomy for Localized Renal Tumors: Optimum Oncological and Renal Functional Considerations /Paul Russo --Nephron-Sparing Surgery for Renal Cancer /Alon Z. Weizer, Jeffery S. Montgomery and Khaled S. Hafez --Thermal Ablation /Surena F. Matin and Kamran Ahrar --Active Surveillance of the Small Renal Mass /Marc C. Smaldone, Daniel Canter, Alexander Kutikov and Robert G. Uzzo --Part 3.Locally Advanced Disease --Locally Advanced Renal Cell Carcinoma /Stephen H. Culp and Christopher G. Wood --Neoadjuvant Targeted Therapy and Consolidative Surgery /Sean P. Stroup and Ithaar H. Derweesh --Part 4.Advanced Disease --Biology of Renal Cell Carcinoma (Vascular Endothelial Growth Factor, Mammalian Target of Rapamycin, Immune Aspects) /Alexandra Arreola and W. Kimryn Rathmell --Prognostic Factors in Advanced Renal Cell Carcinoma /Michael M. Vickers and Daniel Y. C. Heng --Integration of Surgery in Metastatic Renal Cancer /Tom Powles and Axel Bex --Immunotherapy for Renal Cell Carcinoma /Diwakar Davar, Moon Fenton and Leonard J. Appleman --Targeted Therapy: Vascular Endothelial Growth Factor /Linda Cerbone and Cora N. Sternberg --Mammalian Target of Rapamycin in Renal Cell Carcinoma /Eric Jonasch and Michel Choueiri --Palliative and Supportive Care for Renal Cancer /Armida Parala-Metz and Mellar Davis.
  • Pt. 1. Biology of renal cell carcinoma -- pt. 2. Current and future molecular targets for RCC.
  • Targeted therapy for metastatic renal call carcinoma: overview -- Molecular genetics in inherited renal cell carcinoma: identification of targets in the hereditary syndromes -- Molecular targets in renal tumors: pathologic assessment -- Interferons and interleukin-2: molecular basis of activity and therapeutic results -- The molecular biology of kidney cancer and its clinical translation into treatment strategies -- VEGF: biologic aspects and clinical approaches -- VEGF and PDGF receptors: biologic relevance and clinical approaches to inhibition -- Sunitinib and axitinib in renal cell carcinoma -- Sorafenib in renal cell carcinoma -- Additional tyrosine kinase inhibitors in renal cell carcinoma -- Integrin [alpha]5[beta]1 as a novel therapeutic target in renal cancer -- Carbonic anhydrase IX: biology and clinical approaches -- Monoclonal antibody G250 recognizing carbonic anhydrase IX in renal cell carcinoma: biological and clinical studies -- Chemokines in renal cell carcinoma: implications for tumor angiogenesis and metastasis -- P13K/Akt/mTOR pathway: a growth and proliferation pathway -- EGFR and HER2: relevance in renal cell carcinoma -- Proteasome-NF[kappa]B signaling pathway: relevance in RCC -- The role of hepatocyte growth factor pathway signaling in renal cell carcinoma -- Smac/DIABLO: a proapoptotic molecular target in renal cell cancer -- EphA2: a novel target in renal cell carcinoma -- Restoring host antitumoral immunity: how coregulatory molecules are changing the approach to the management of renal cell carcinoma -- The role of gangliosides in renal cell carcinoma -- Tumour necrosis factor: misnomer and therapeutic target -- Molecular markers for predicting prognosis of renal cell carcinoma -- Adjuvant therapy for renal cell carcinoma: targeted approaches.
  • Renal Disease in Cancer Patients is a translational reference detailing the nephrological problems unique to patients with cancer in an organized and authoritative fashion. This book provides a common language for nephrologists, oncologists, hematologists, and other clinicians who treat cancer patients, to discuss the development of renal diseases in the context of cancer and options for their optimum diagnosis, management, and treatment. With the advent of better supportive care and the era of personalized medicine, patients with cancer are living longer, and oncologists and nephrologists now recognize the serious consequences of renal disease among these patients. Designed especially with this new need in mind, Renal Disease in Cancer Patients presents the various renal diseases affecting cancer patients in a single, authoritative volume. The book covers topics in radiation nephritis, obstructive nephropathy, drug nephropathy, graft-versus-host disease, and more. Covers clinical description, diagnostics, management, and treatment throughout along with genetics, animal models, and pathology in specific chaptersSummarizes all renal diseases unique to cancer patients in a single reference. Provides a resource for oncologists and nephrologists, as well as general internal and family medicine practitioners, and physicians in training.
  • Assessment of Renal Function / Mohan Arkanath -- Imaging of Acute Renal Failure - A Problem-Solving Approach for Intensive Care Unit Physicians / Tom Sutherland -- Drug-Induced Renal Injury / Sara Blakeley -- Acute Kidney Injury / Sara Blakeley -- Medical Management of Acute Renal Failure / Nerina Harley -- Acute Renal Failure in the Surgical Patient / Marlies Ostermann -- Rhabdomyolysis and Compartment Syndrome / Laurie Tomlinson and Stephen Holt -- Multisystem Causes of Acute Renal Failure / Tim Leach -- Therapeutic Plasma Exchange / Tim Leach -- Renal Replacement Therapy / John H. Reeves -- Technical Aspects of Renal Replacement Therapy / Sara Blakeley -- End-Stage Renal Disease / Emile Mohammed -- Clinical Hyperkalemia and Hypokalemia / Harn-Yih Ong -- Clinical Hyponatremia and Hypernatremia / Himangsu Gangopadhyay -- Clinical Metabolic Acidosis and Alkalosis / Sara Blakeley.
  • Renal neoplasms 2014, Springer
    Renal Neoplasms: An Integrative Approach to Cytopathologic Diagnosis provides a comprehensive review of cytology and all the morphologic correlates, including their respective limitations, related to a broad spectrum of renal neoplasms with special emphasis on cyto-histo correlation. The book also discusses related usual radiologic appearances, gross features and possible targeted therapies where appropriate. The volume features an integrated approach that provides step-by-step guidance in the morphologic evaluation of renal neoplasms. Furthermore, all chapters are written by experts who deal with this type of specimen in their daily practice and have insights into the pathology as well as the clinical aspects of these tumors. Illustrated with high quality color microphotographs and formatted for ease of use in the lab, Renal Neoplasms: An Integrative Approach to Cytopathologic Diagnosis is a helpful guide to everyday pathology practice, especially for pathologists who rarely encounter this type of specimen.
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    Review of renal physiology -- Regulation of salt and water balance -- Disorders of water balance : hyponatremia, hypernatremia, and polyuria -- Edematous states and the use of diuretics -- Acid-base physiology and metabolic alkalosis -- Metabolic acidosis -- Disorders of potassium balance -- Urinalysis and approach to the patient with renal disease -- Pathogenesis of major glomerular and vascular diseases -- Progression of chronic renal failure -- Acute renal failure -- Signs and symptoms of chronic renal failure -- Tubulointerstitial diseases.
  • Renal pharmacotherapy 2013, Springer
    As the population of patients with acute or chronic kidney disease grows, healthcare professionals need a resource that optimizes drug effectiveness while minimizing potential toxicity. Renal Pharmacotherapy is a comprehensive listing of dosage recommendations for patients with compromised renal function. This up-to-date and evidence-based reference closes several identified knowledge gaps concerning medications eliminated by the kidneys. Conveniently listed alphabetically by generic drug name, each drug has its own face page featuring typical dosing ranges, alternative dosing adjustments by strata of renal function, specific dosing for dialysis and other dosing schemes.This work will satisfy the dosing information needs of busy physicians involved in pharmacotherapy for patients with kidney disease, as well as pharmacists, nurses and students.
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  • Renal vascular disease 2014, Springer
    This book describes the recent advances in the understanding of the development and management of renal vascular disease (RVD). Current perspectives regarding the epidemiology of atherosclerotic RVD, its clinical manifestations, and the interaction with injury pathways related to the kidney have evolved considerably, and the widespread introduction of non-invasive methods for identification of RVD using ultrasound, CT, and MR imaging has allowed more facile identification of these diseases than ever before. Renal Vascular Disease provides an accessible, up-to-date summary of the pathophysiology and management of RVD. The clinical paradigms that are emerging in the field, both in regards to RVD and its role in chronic kidney disease (CKD), cardiovascular risk, and the cardiorenal syndromes are discussed in this comprehensive text, making it an essential resource for clinicians and investigators who tackle the challenges of RVD.
  • Systemic versus local renin angiotensin systems: An overview / W.C. DeMello and R.N. Re -- Clinical import of the local renin angiotensin aldosterone systems / E.D. Frohlich -- Renin, prorenin, and the (pro)renin receptor / G. Nguyen and A. Contrepas -- Local renin angiotensin systems in the cardiovascular system / R.N. Re -- Renin-angiotensin-aldosterone system and pathobiology of hypertension / P. Paradis and E.L. Schiffrin -- AT{subscript]1 receptors, angiotensin receptor blockade, and clinical hypertensive disease / R.M. Carey -- Structural and electrophysiological remodeling of the failing heart / W.C. DeMello -- Inhibiting the renin angiotensin aldosterone system in patients with heart failure and myocardial infarction / M.A. Pfeffer -- Left ventricular hypertrophy and treatment with renin angiotensin system inhibition / E.D. Frohlich and J. Díez -- Angiotensin-(1-7), angiotensin-converting enzyme 2, and new components of the renin angiotensin system / A.J. Trask ... [et al.] -- Kinin receptors and ACE inhibitors: An interrelationship / E.G. Erdös, F. Tan and R.A. Skidgel -- Kinins and cardiovascular disease / O.A. Carretero, X.-P. Yang and N.-E. Rhaleb -- CMS and type 2 diabetes mellitus: Bound together by the renin angiotensin aldosterone system / D. Gupta ... [et al.] -- Renin angiotensin aldosterone system and cardiovascular disease / S. Bernard ... [et al.] -- Renin angiotensin system and atherosclerosis / C. Hu and J.L. Mehta -- Renin angiotensin system and aging / L.F. Ferder.
  • Overview of the pancreas -- Physiology of the pancreas -- Common pancreatic disease -- Circulating RAS -- Local RAS -- Pancreatic RAS -- Basic techniques for pancreatic research -- Current research of the RAS in diabetes mellitus -- Current research concerning the RAS in pancreatic stem cells -- Current research of the RAS in pancreatitis and pancreatic cancer.
  • Provides tools to assist emergency planners in evaluating the feasibility of, and requirements for, reopening shuttered hospitals in their local communities to expand surge capacity during a mass casualty event
  • Reoperative hand surgery 2012, Springer
    Reoperative Hand Surgery is a major contribution to the literature, offering a wide range of reoperative options for challenging problems that face the reconstructive hand surgeon after failed primary surgery. Concise and discussing all of the more common issues that hand surgeons often face in performing revision surgery, this invaluable title is unique in that it looks specifically at the problem of what to do when the original index procedure did not go as planned. Topics covered include the hand, wrist, forearm and elbow, and several sections of the book discuss some of the psychological and social factors that also go into the decision process to reoperate or not. The chapters are tightly focused so that the important aspects to consider for reoperation can be quickly reviewed. There is also a component that discusses how to avoid other pitfalls and to minimize as well as manage any complications that may occur with reoperative procedures. Importantly, the book is replete with original art work to help describe and demonstrate how to perform many reoperative procedures. The artwork is simple and straightforward but yet detailed enough to convey the important steps and aspects for the surgical intervention it is outlining. Developed by renowned experts in the hand surgery field, Reoperative Hand Surgery is an indispensable, state-of-the-art reference, offering the busy hand and upper extremity surgeon easily accessible information relating to the evaluation, diagnosis, and possible surgical interventions for the diagnoses discussed.
  • Reoviruses 2006, Springer
    Attachment and cell entry of mammalian orthoreovirus / K.M. Guglielmi ... [et al.] -- Early steps in rotavirus cell entry / S. Lopez and C.F. Arias -- Early steps in avian reovirus morphogenesis / J. Benavente and J. Martinez-Costas -- Bluetongue virus assembly and morphogenesis / P. Roy and R. Noad -- Reovirus structure and morphogenesis / K.M. Coombs -- Rotavirus genome replication and morphogenesis : role of the viroplasm / J.T. Patton ... [et al.] -- Rotavirus proteins : structure and assembly / J.B. Pesavento ... [et al.] --- Structural studies on orbivirus proteins and particles / D.I. Stuart and J.M. Grimes -- Rotavirus assembly : an alternative model that utilizes and atypical trafficking pathway / S. Chwetzoff and G. Trugnan.
  • Tendon repair and regeneration: an overview / Eric M. Bluman, Scott D. Allen, Paul D. Fadale -- Structure and function of ligaments, tendons, and joint capsule / Frederick H. Silver, Joseph W. Freeman, Gino Bradica -- Tendons of the hand: anatomy, repair, healing, and rehabilitation / Paul C. Stephens ... [et al.] -- Evolution of concepts in flexor tendon surgery of the hand / Randip R. Bindra -- Basic science of the shoulder ligaments / Louis J. Soslowsky and Jeffrey S. Cartmell -- History of cruciate ligaments: development of repair and reconstruction / Jon Karlsson -- Rotator cuff / Richard O. Evans, Peter J. Hughes, David H. Sonnabend -- Frozen shoulder / Peter J. Hughes, Richard O. Evans, Jerome A. Goldberg -- Capsular shrinkage of the shoulder: current clinical status / Andrew L. Wallace -- Biomechanical and clinical evaluation of tendons and ligaments / David Hartright ... [et al.] -- Healing of ligament and tendon to bone / Andreas Weiler, Sven Scheffler, Maria Apreleva -- Artificial ligaments / Andrew A. Amis -- Tendon and ligament fixation to bone / Christopher M. Hill, Yuehuei H. An, Frank A. Young -- Tissue engineering strategies for regeneration of the anterior cruciate ligament / Michael G. Dunn -- Gene therapy and ligament healing / Norimasa Nakamura.
  • Reparative medicine v. 961, 2002, Wiley
  • Repetitive DNA 2012, Karger
    The Repetitive DNA Content of Eukaryotic Genomes / López-Flores, I.; Garrido-Ramos, M.A. -- Telomere Dynamics in Mammals / Silvestre, D.C.; Londoño-Vallejo, A. -- Drosophila Telomeres: an Example of Co-Evolution with Transposable Elements / Silva-Sousa, R.; López-Panadès, E.; Casacuberta, E. -- The Evolutionary Dynamics of Transposable Elements in Eukaryote Genomes / Tollis, M.; Boissinot, S. -- SINEs as Driving Forces in Genome Evolution / Schmitz, J. -- Unstable Microsatellite Repeats Facilitate Rapid Evolution of Coding and Regulatory Sequences / Jansen, A.; Gemayel, R.; Verstrepen, K.J. -- Satellite DNA Evolution / Plohl, M.; Meštrović, N.; Mravinac, B. -- Satellite DNA-Mediated Effects on Genome Regulation / Pezer, Ž.; Brajković, J.; Feliciello, I.; Ugarković, Đ. -- The Birth-and-Death Evolution of Multigene Families Revisited / Eirín-López, J.M.; Rebordinos, L.; Rooney, A.P.; Rozas, J. -- Chromosomal Distribution and Evolution of Repetitive DNAs in Fish / Cioffi, M.B.; Bertollo, L.A.C..
  • Repetitive transcranial magnetic stimulation (rTMS) treatment is increasingly being used in the management of patients with depression. Since the approval of one rTMS device in the United States in 2008, clinical services using this equipment have become relatively common there, and services are also being developed in a variety of other countries. However, considerable ignorance exists about the treatment in general psychiatric practice. This concise clinical guide will serve as a reference and practical tool for clinicians working with or learning about this treatment technique. The opening chapters provide basic information on the history and development of rTMS treatment and its mechanism of action. Use of the treatment in depression is then addressed in detail, with explanation of the evidence base and discussion of clinical issues such as selection of patients and type of treatment, dose, and treatment duration. Side-effects of treatment are explored, and careful consideration is given to various practical issues concerning the establishment of rTMS treatment programs and the training of clinicians. The final chapters will provides a brief overview of potential rTMS applications in other psychiatric conditions and some background on the use of related treatments, such as transcranial direct current stimulation.
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  • Replicating vaccines 2011, Springer
    Live vaccines and their role in modern vaccinology / Gordon Dougan, David Goulding, and Lindsay J. Hall -- Live attenuated vaccines : influenza, rotavirus and varicella zoster virus / Harry B. Greenberg and Ann M. Arvin -- Classical live viral vaccines / Thomas P. Monath -- Recombinant live vaccines to protect against the severe acute respiratory syndrome coronavirus / Luis Enjuanes ... [et al.] -- Live-attenuated Shigella vaccines. Is encouraging good enough? / Yves Germani and Philippe J. Sansonetti -- New generation BCG vaccines / Michael V. Tullius and Marcus A. Horwitz -- Basic science paves the way to novel safe and effective pestivirus vaccines / Norbert Tautz and Gregor Meyers -- Live attenuated influenza virus vaccines : NS1 truncation as an approach to virus attenuation / Natalie Pica, Peter Palese, and John Steel -- An attenuated HSV-1 live virus vaccine candidate that is replication competent bu defective in epithelial cell-to-cell and neuronal spread / Elizabeth E. Zumbrun and Harvey M. Frieman -- Live attenuated vaccines for respiratory syncytial virus / Michael N. Teng -- Live attenuated cholera vaccines : flagella and reactogenicity / D. Ewen Cameron and John J. Mekalanos -- Replication-defective herpes simplex virus mutant strains as genital herpes vaccines and vaccine vectors / David M. Knipe -- Nucleic acid-based infections and pseudo-infectious flavivirus vaccines / Justin A. Roby, Roy A. Hall, and Alexander A. Khromykh -- Application of cleavage activation mutants of influenza virus as live vaccines / Juergen Stech and Hans-Dieter Klenk -- Alphavirus particle-based vaccine vectors / Scott J. Balsitis, Clayton W. Beard, and Peter W. Mason -- Recombinant chimeric, live attenuated vaccines against flaviviruses and alphaviruses / Thomas P. Monath.
  • Red Book Online is the online home of the Report of the AAP Committee on Infectious Diseases. Offering instant Web-based access, Includes complete text of the Red Book, plus the complete visual library of images from the Visual Red Book on CD-ROM and more.
  • Volume 2 has country-by-country analysis.
  • The Food and Agriculture Organization of the United Nations and the World Health Organization convened a Joint Expert Consultation on the Risks and Benefits of Fish Consumption from 25 to 29 January 2010. The tasks of the Expert Consultation were to review data on levels of nutrients (long-chain omega-3 fatty acids) and specific chemical contaminants (methylmercury and dioxins) in a range of fish species and to compare the health benefits of fish consumption and nutrient intake with the health risks associated with contaminants present in fish. The Expert Consultation drew a number of conclusions regarding the health benefits and health risks associated with fish consumption and recommended a series of steps that Member States should take to better assess and manage the risks and benefits of fish consumption and more effectively communicate these risks and benefits to their citizens. The output of the Expert Consultation is a framework for assessing the net health benefits or risks of fish consumption that will provide guidance to national food safety authorities and the Codex Alimentarius Commission in their work on managing risks, taking into account the existing data on the benefits of eating fish. The Expert Consultation concluded the following: Consumption of fish provides energy, protein and a range of other important nutrients, including the long-chain n-3 polyunsaturated fatty acids (LCn3PUFAs). Eating fish is part of the cultural traditions of many peoples. In some populations, fish is a major source of food and essential nutrients. Among the general adult population, consumption of fish, particularly fatty fish, lowers the risk of mortality from coronary heart disease. There is an absence of probable or convincing evidence of risk of coronary heart disease associated with methylmercury. Potential cancer risks associated with dioxins are well below established coronary heart disease benefits from fish consumption. When comparing the benefits of LCn3PUFAs with the risks of methylmercury among women of childbearing age, maternal fish consumption lowers the risk of suboptimal neurodevelopment in their offspring compared with the offspring of women not eating fish in most circumstances evaluated. At levels of maternal exposure to dioxins (from fish and other dietary sources) that do not exceed the provisional tolerable monthly intake (PTMI) of 70 pg/kg body weight established by JECFA (for PCDDs, PCDFs and coplanar PCBs), neurodevelopmental risk for the fetus is negligible. At levels of maternal exposure to dioxins (from fish and other dietary sources) that exceed the PTMI, neurodevelopmental risk for the fetus may no longer be negligible. Among infants, young children and adolescents, the available data are currently insufficient to derive a quantitative framework of the health risks and health benefits of eating fish. However, healthy dietary patterns that include fish consumption and are established early in life influence dietary habits and health during adult life.
  • Report on carcinogens Latest <11th, 2005>
    The report includes listings of substances, divided into two categories: known human carcinogens and substances reasonably anticipated to be human carcinogens.
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  • Reporter genes 2007, Springer Protocols
    Methodologies for staining and visualization of [beta]-galactosidase in mouse embryos and tissues / Siobhan Loughna and Deborah Henderson -- Immunohistochemical detection of [beta]-galactosidase or green fluorescent protein on tissue sections / Philip A. Seymour and Maike Sander -- Detection of reporter gene expression in murine airways / Maria Limberis, Peter Bell, and James M. Wilson -- Three-dimensional analysis of molecular signals with episcopic imaging techniques / Wolfgang J. Weninger and Timothy J. Mohun -- Fluorescent proteins for cell biology / George H. Patterson -- Detection of GFP during nervous system development in Drosophila melanogaster / Karin Edoff, James S. Dods, and Andrea H. Brand -- Autofluorescent proteins for flow cytometry / Charles G. Bailey and John E. J. Rasko -- Fluorescent protein reporter systems for single-cell measurements / Steven K. Dower, Eva E. Qwarnstrom, and Endre Kiss-Toth -- Subcellular imaging of cancer cells in live mice / Robert M. Hoffman -- Noninvasive imaging of molecular events with bioluminescent reporter genes in living subjects / Pritha Ray and Sanjiv Sam Gambhir -- Green fluorescent protein as a tracer in chimeric tissues : the power of vapor fixation / Harald Jockusch and Daniel Eberhard.
  • Representation and brain 2007, Springer
  • Representation in mind 2004, ScienceDirect
  • Representing Argentinian mothers 2013, IngentaConnect
  • Perspectives on reproduction and life history in baboons / Larissa Swedell & Steven R. Leigh -- Infant mortality, paternity certainty, and female reproductive strategies in hamadryas baboons / Larissa Swedell & Julian Saunders -- Female behavioral strategies of hybrid baboons in the Awash National Park, Ethiopia / Jacinta C. Beehner & Thore J. Bergman -- Hybrid baboons and the origins of the hamadryas male reproductive strategy / Thore J. Bergman -- The social and ecological flexibility of Guinea baboons : implications for Guinea baboon social organization and male strategies / Anh Galat-Luong, Gérard Galat & Suzanne Hagell -- Social organization, reproductive systems, and mediation of baboon endogenous virus (BaEV) copy number in gelada, hamadryas, and other Papio baboons / Monica Uddin, Jane E. Phillips-Conroy & Clifford J. Jolly -- Reproduction, mortality, and female reproductive success in chacma baboons of the Okavango Delta, Botswana / Dorothy L. Cheney ... [et al.] -- Maternal characteristics and offspring growth in chacma baboons : a life-history perspective / Sara E. Johnson -- Whose life is it anyway? Maternal investment, developmental trajectories, and life history strategies in baboons / Louise Barrett, S. Peter Henzi & John E. Lycett -- Ontogeny, life history, and maternal investment in baboons / Steven R. Leigh & Robin M. Bernstein -- Testicular size, developmental trajectories, and male life history strategies in four baboon taxa / Clifford J. Jolly & Jane E. Phillips-Conroy -- The evolutionary past and the research future : environmental variation and life history flexibility in a primate lineage / Susan C. Alberts & Jeanne Altmann.
  • Reproductive toxicology is a complex subject dealing with three components-parent, placenta, and fetus-and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife.
  • Basis for molecular reproductive biology -- Introduction to the molecular organization of the endocrine/reproductive system -- Extracellular signaling receptors -- Molecules that transmit information into the cell: the intracellular signaling pathways -- Introduction to molecular biology: structure and function of the macromolecules of genetic information -- Regulation of gene expression -- Molecular basis of abnormal phenotype -- Tools of molecular reproductive biology -- Recombinant DNA technology -- Techniques for DNA analysis -- Analyzing gene expression -- DNA microarray analysis -- Computer assisted analysis of genes -- Introduction to gene therapy -- Molecular regulation of reproductive hormones -- GnRH-GnRH-receptor system in the mammalian female reproductive tract -- FSH: one hormone with multiple forms, or a family of multiple hormones -- FSH receptor: one receptor with multiple forms or a family of receptors -- Regulation of the early steps in gonadal steroidogenesis -- Prostaglandins and their mechanisms of action in the cyclic ovary -- Androgens: molecular basis and related disorders -- Leptin as a reproductive hormone -- Neurosteroids and sexual behavior and reproduction -- Molecular regulation of the reproductive organs and tissues -- Autocrine and paracrine regulation of the ovary -- Ovarian endocrine activity: role of follistatin, activin, and inhibin -- Hormonal and molecular regualtion of the cytochrome P450 aromatase gene expression in the ovary -- Epigenetic mechanisms of ovarian gene regulation -- Ovarian function and failure: the role of the oocyte and its molecules -- Molecular control of corpus luteum function -- Molecular landscape of spermatogonial stem cell renewal, meiotic sex chromosome inactivation, and spermatic head shaping.
  • Characteristics of a successful R.E.I. clinic and laboratory -- Assisted reproductive technology practice management -- Collaboration within the reproductive endocrinology and infertility practice: integration of laboratory and clinic operations -- Informed consent in advanced reproductive technology -- Reproductive laboratory regulations, certifications and reporting systems -- Successfully integrating the FDA regulations into your practice -- Psychosocial consequences of infertility and treatment -- A live baby or your money back: the marketing of in vitro fertilization procedures -- Ovulation: a molecular view -- Clinical evaluation of female factor infertility -- Polycystic ovary syndrome -- The current status for Metformin use in reproductive medicine -- Clinical aspects of endometriosis -- Common endocrinopathies in reproductive endocrinology -- Acquired uterine factors and infertility -- Mullerian (paramesonephric) anomalies and associated Wolffian (mesonephric) duct malformations -- Recurrent miscarriage -- Laparoscopy in the diagnosis and treatment of female infertility -- Turner syndrome -- Errors in chromosome segregation during oogenesis and early embryogenesis -- An overview of sperm production -- Meiotic recombination and errors during spermatogenesis -- Clinical evaluation and treatment of male factor infertility -- Semen analysis: essentials for the clinician -- Sperm capacitation, the acrosome reaction, and fertilization -- Advanced tests of sperm function -- Genetic testing of male infertilityVaricocele and male infertility -- Sperm retrieval techniques -- The clinical utility of the evaluation of sperm chromatin -- Artificial insemination: intrauterine insemination -- Sperm preparation for artificial insemination -- Sperm banking, donation, and transport in the age of assisted reproduction: federal and state regulation -- Reproductive treatment of HIV-1 discordant couples -- Ovulation induction -- Transvaginal sonography in reproductive endocrinology and infertility -- Establishing the IVF laboratory: a systems view -- Preparation and selection of sperm for IVF and ICSI -- The genetic and epigenetic contributions of sperm to early embryogenesis -- Micromanipulation of human oocytes and embryos: applications of intracytoplasmic sperm injection and assisted hatching in infertility treatment -- Embryo culture techniques -- In-vitro maturation of human oocytes -- Integrating preimplantation genetic diagnosis into the ART laboratory -- Evaluation and selection of preimplantation embryos for transfer -- Embryo transfer in IVF: evidence-based clinical practice -- Cryopreservation of human oocytes and embryos -- Preserving fertility -- Ovarian hyperstimulation syndrome -- Pregnancy outcomes in infertile couples -- The impact of complementary medicine on in-vitro fertilization -- Designing a clinical research infrastructure -- Integrating research into a clinical practice -- Research regulations: the role of the Institutional Review Board -- Technology transfer and its role in the practice of reproductive endocrinology and infertility -- The environment and reproduction: endocrine disruption, reproductive impairment, and epigenetics.
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    Foundations of reproductive epidemiology -- Environments in reproductive epidemiology -- Research process in reproductive epidemiology -- Surveillance in reproductive epidemiology -- Descriptive reproductive health indicators -- Study designs in reproductive epidemiology -- Causal inference in reproductive epidemiology -- Nutrition and reproductive health -- Contraception and reproductive health -- Mercury, lead, environmental estrogens, and reproductive health -- Psychosocial factors and reproductive health -- Early childbearing : trends and consequences -- Cancer risk associated with early and late maternal age at first birth.
  • Principles of cancer treatment: impact on reproduction -- Fertility preservation options for females -- Options for fertility preservation in men and boys with cancer -- Contraception and cancer treatment in young persons -- Sexual health during cancer treatment -- Unique reproductive concerns of young women with breast cancer -- Pregnancy and cancer -- Preimplantation genetic diagnosis for hereditary cancers -- Non-traditional family building planning -- Parenting with cancer I: developmental perspective, communication, and coping -- Parenting with cancer II: parenting at different stages of illness -- Pediatric oncology and reproductive health -- Institutional approaches to implementing fertility preservation for cancer patients -- Patient provider communication and reproductive health -- Fertility preservation in cancer patients: ethical considerations -- Legal issue and of assisted reproductive technologies.
  • Introduction --Environmental Impact on Reproductive Health, Recent Trends and Developments /P. Nicolopoulou-Stamati and N.J. Lelos.Section 1: The Link Between Reproductive Health and Environment. --Epidemiological Studies on the Relationship between Semen Quality and Environmental Chemicals: Historic and Contemporary Compounds /R. Hauser and J.D. Meeker --Environment and Fertility /P. Saldiva.Section 2: Reproductive Health Effects. --Male Reproductive Status and its Relationship with Man-Made, Hormone-Disrupting Substances: Studies In Flanders, Belgium /W. Dhooge, F. Eertmans, A. Mahmoud, and F. Comhaire --Potential Impact of the Environment on the Male Reproductive Function: The Example Of Cryptorchidism /E. Huyghe, R. Mieusset and P.F. Thonneau --Advanced Glycation End Products in Polycystic Ovarian Syndrome /E. Diamanti-Kandarakis, C. Piperi, and P. Nicolopoulou-Stamati --Oocytes and Ovarian Follicles as Targets of Endocrine Disrupters: Consequences for Reproductive Health /F. Gandolfi, T.A.L. Brevini, and F. Cillo.Section 3: Pollutants And Exposure. --Non-Pesticide Endocrine Disrupters and Reproductive Health /S. Corsolini --Medical Drugs Impairing Fertility /N. Pandiyan --Impact of Air Pollution on Reproductive Health in Northern Bohemia /J. Rubes, S.G. Selevan, R.J. Sram, D.P. Evenson, and S.D. Perreault.Section 4: Policy Instruments And Issues. --Pesticides as Endocrine Disrupters: Identification of Hazards for Female Reproductive Function /M. Rescia and A. Mantovani --Assessment of Fertility and Other Health Impacts for Selected Pollutants in Flanders: Opportunities and Limitations /J. De Wit, A. Verspecht and L. Hens --Problems in Assessing Low Dose Effects of Endocrine Disrupters /A. Gies --Getting the Message Across - WWFs and ISDEs Perspectives on Communication Strategies to Reduce Exposures to Hazardous Chemicals /G. Lyons and P. Illig --Environmental Ethics and Fertility in Early Cultures and The Industrial Age /A. Katsivelaki and C.E. Sekeris.Section 5: Regional Aspects. --Reproductive Health Problems in the Greater Athens Area /D.A. Adamopoulos and E. Koukkou --Environment and Reproductive Health in Bulgaria /S. Stoyanov and E. Terlemesian.
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    About these guidelines -- Introduction -- Indicators-an overview in the context of global monitoring -- Generation, interpretation and analysis of the shortlisted national reproductive health indicators -- 1. Total fertility rate -- 2. Contraceptive prevalence -- 3. Maternal mortality ratio -- 4. Antenatal care coverage -- 5. Births attended by skilled health personnel -- 6. Availability of basic essential obstetric care -- 7. Availability of comprehensive essential obstetric care -- 8. Perinatal mortality rate -- 9. Prevalence of low birth weight -- 10. Prevalence of positive syphilis serology in pregnant women -- 11. Prevalence of anaemia in women -- 12. Percentage of obstetric and gynaecological admissions owing to abortion -- 13. Reported prevalence of women with genital mutilation -- 14. Prevalence of infertility in women -- 15. Reported incidence of urethritis in men -- 16. Prevalence of HIV infection in pregnant women -- 17. Knowledge of HIV-related preventive practices -- Annex 1. Millennium Development Goals and associated targets -- Annex 2. The selection criteria for the shortlist of indicators.
  • "Metabolic engineering has been developed over the past 20 years to become an important tool for the rational engineering of industrial microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of different metabolites. The overall goal is to achieve a better understanding of the metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved biochemical production. This book brings together contributions from leading researchers at the cutting edge of these topics. The subject matter is divided into two sections. The first section deals with novel and emerging methods for redesigning microorganisms exploiting systems biology and gene regulation. The second discusses practical aspects of metabolic engineering for over production of a variety of valuable chemicals and materials by fermentation."--Publisher's description.
  • "This overview outlines the statutory background for WHO's research, identifies the milestones in health research over five decades, and discusses issues of both process and programs. This report also includes accounts of regional efforts in health research"--Publisher's description.African region; Eastern Mediterranean region; European region; South East Asia region; Western Pacific region; Pan American Health Organization
  • It has become increasingly accepted that important digital data must be retained and shared in order to preserve and promote knowledge, advance research in and across all disciplines of scholarly endeavor, and maximize the return on investment of public funds. To meet this challenge, colleges and universities are adding data services to existing infrastructures by drawing on the expertise of information professionals who are already involved in the acquisition, management and preservation of data in their daily jobs. Data services include planning and implementing good data management practices, thereby increasing researchers' ability to compete for grant funding and ensuring that data collections with continuing value are preserved for reuse. This volume provides a framework to guide information professionals in academic libraries, presses, and data centers through the process of managing research data from the planning stages through the life of a grant project and beyond. It illustrates principles of good practice with use-case examples and illuminates promising data service models through case studies of innovative, successful projects and collaborations.
  • Research in Clinical Practice is a neat, pocket-sized reference guide examining how to get the most from actively participating in research. Including how to begin, avoiding pitfalls, whom to approach and what questions to ask - all significant practicalities for conducting research in the reader's area of interest. Each reader will learn how to make the best use of such a valuable time. Written by two experienced surgeons, both of whom achieved post graduate research degrees, Research in Clinical Practice, is an essential tool for clinicians embarking on a research project as well as those who are new to supervising researchers.
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    Introduction to research / Carol Noll Hoskins and Carla Mariano -- The research question / Carol Noll Hoskins and Carla Mariano -- A review of the literature: using online and print sources / Barbara Carty, Susan Kaplan Jacobs, Carol Noll Hoskins, and Carla Mariano -- Theoretical and conceptual frameworks / Carol Noll Hoskins and Carla Mariano -- Research designs / Carol Noll Hoskins and Carla Mariano -- Sampling methods: basic issues and concepts / Joseph Giacquinta and Carla Mariano -- Principles of measurement / Carol Noll Hoskins -- Development of quantitative methods / Carol Noll Hoskins -- Data analysis and interpretation / Carol Noll Hoskins and Carla Mariano -- Product of the inquiry: the research report / Carol Noll Hoskins and Carla Mariano -- Guide to critique of quantitative research with examples and practice studies / Carol Noll Hoskins -- Guide to critique of qualitative research with examples and practice studies / Carla Mariano.
  • Topics include self-Management, self-Efficacy, health Status, and some diabetes-specific scales.
  • This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in biomineralization science, and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure.
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  • The orthodontic literature includes many articles on basic science and engineering research techniques, but clinicians are typically unfamiliar with the principles underlying these techniques and may also lack the background knowledge required for a full appreciation of their role. This book comprehensively reviews a wide array of the research methods most frequently encountered in the literature, encompassing the areas of materials science and clinical and biological research. The various methods and techniques are carefully described, and their indications and limitations are explained. All of the information is up to date, reflecting latest developments.For practicing professionals, Research Methods in Orthodontics will be an ideal introduction to instrumental analysis and basic science research methods in the field. It will also serve as an excellent reference guide for researchers. By familiarizing orthodontists with the basics of research methods, the book will boost their ability to keep pace with developments in treatment approaches, materials, and techniques and assist in the transfer of relevant future findings into practice.
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    Ethical and practice issues in qualitative research / Frances Sheldon and Anita Sargeant -- Evaluating qualitative research / Michelle Crossley -- Mixed methods for evaluation research / Christine Ingleton and Sue Davies -- Ethnography / Jane Seymour -- Documentary analysis and policy / Margaret O'Connor -- How to develop a research question / Laura Kelly and Patrick Stone -- Writing a research proposal / Chris Todd -- How to gain research ethics approval / Peter Speck -- How to use a statistician / Malcolm Campbell -- How to write a paper / Julia M. Addington-Hall.Principles of designing clinical trials in palliative care / Michael I. Bennett -- Ethical and practical issues in designing and conducting clinical trials in palliative care / Yolanda Zuriarrain Reyna, Michael I. Bennett, and Eduardo Bruera -- Survey design / Julia M. Addington-Hall -- Survey research : methods of data collection, questionnaire design, and piloting / Julia M. Addington-Hall -- Experimental and quasi-experimental designs / Massimo Costantini and Irene J. Higginson -- Outcome measurement / Irene J. Higginson and Richard Harding -- Systematic reviews / Marjolein Gysels and Irene J. Higginson -- Qualitative methods of data collection and analysis / Sheila Payne --
  • pt. B, 2011 ScienceDirect
  • Trefoil factor family peptide 3 at the ocular surface / Schulze, U.; Sel, S.; Paulsen, F.P. -- Cationic amino acid transporters and [beta]-defensins in dry eye syndrome / Jäger, K. ... [et al.] -- Antimicrobial peptides as a major part of the innate immune defense at the ocular surface / Garreis, F.; Gottschalt, M.; Paulsen, F.P. -- Regulation of the inflammatory component in chronic dry eye disease by the eye-associated lymphoid tissue (EALT) / Knop, N.; Knop, E. -- Intravital multidimensional real-time imaging of the conjunctival immune system / Gehlsen, U.; Hüttmann, G.; Steven, P. -- Generation of two- and three-dimensional lacrimal gland constructs / Schrader, S. ... [et al.] -- Midterm results of cultivated autologous and allogeneic limbal epithelial transplantation in limbal stem cell deficiency / Pauklin, M. ... [et al.] -- Laser scanning confocal microscopy for conjunctival epithelium imaging / Jürgens, C. ... [et al.] -- Pollen enzymes degrade human tear fluid and conjunctival cells : an approach to understanding seasonal non-allergic conjunctivitis / Rabensteiner, D.F. ... [et al.] -- Towards a new in vitro model of dry eye : the ex vivo eye irritation test / Spöler, F.; Frentz, M.; Schrage, N.F. -- The lid margin is an underestimated structure for preservation of ocular surface health and development of dry eye disease / Knop, E. ... [et al.] -- Diagnostic markers of sjögrenʹs syndrome / Witte, T. -- Hyperosmolarity of the tear film in dry eye syndrome / Messmer, E.M.; Bulgen, M.; Kampik, A. -- Novel ocular lubricant containing an intelligent delivery system: details of its mechanism of action / Springs, C.
  • Research proposals. 3rd ed. 2002, ScienceDirect
    Part One: Beginning grantsmanship -- 1. The NIH and other sources of research support -- 2. A strong proposal -- 3. Proposal review -- 4. The R01 research grant -- 5. The abstract and specific aims -- 6. Background and significance -- 7. Preliminary studies -- 8. Research design and methods -- 9. The budget -- 10. Biographical sketch, research support, and resources -- 11. Human subjects -- 12. Animal subjects -- 13. Consortiums, contracts, consultants, and collaborators -- 14. Literature cited and appendixes -- 15. Revision of an unfunded proposal -- 16. Competing renewal of R01 projects (progress reports) -- 17. Proposal submission and supplementary materials -- 18. Your first grant award (R, F, or K) -- 19. Advice for beginners in academia. -- Part two: Advanced grantsmanship -- 20. Small business grants -- 21. Program project grants (P01) -- 22. Center grants -- 23. Construction grants -- 24. T32 institutional research training program grants -- 25. Instrumentation grants -- Appendix -- A. Information sources: private foundation and government web sites, and study section contacts -- B. Summary statements, reviewer comments, assignment, award, and triage letters -- C. Examples of figures from preliminary data -- D. Examples of design format -- E. Instructions to reviewers concerning human subjects -- F. Suggested reading.
  • "Comprehensive research and a highly trained workforce are essential for the improvement of health and health care both nationally and internationally. Over the past 40 years the National Research Services Award (NRSA) Program has played a large role in training the workforce responsible for dramatic advances in the understanding of various diseases and new insights that have led to more effective and targeted therapies. In spite of this program, the difficulty obtaining jobs after the postdoc period has discouraged many domestic students from pursuing graduate postdoc training. In the United States, more than 50 percent of the postdoc workforce is made up of individuals who obtained their Ph. D.s from other countries. Indeed, one can make a strong argument that the influx of highly trained and creative foreigners has contributed greatly to U.S. science over the past 70 years. Research Training in the Biomedical, Behavioral, and Clinical Research Sciences discusses a number of important issues, including: the job prospects for postdocs completing their training; questions about the continued supply of international postdocs in an increasingly competitive world; the need for equal, excellent training for all graduate students who receive NIH funding; and the need to increase the diversity of trainees. The book recommends improvements in minority recruiting, more rigorous and extensive training in the responsible conduct of research and ethics, increased emphasis on career development, more attention to outcomes, and the requirement for incorporating more quantitative thinking in the biomedical curriculum."--Publisher's description.
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    1. Violence against women as a health and development issue -- 2. Ethical considerations for researching violence against women -- 3. Developing a research strategy -- 4. Quantitative approaches to research -- 5. Qualitative approaches to research -- 6. The challenge of defining and measuring violence in quantitative research -- 7. Developing a sampling strategy -- 8. Tools for collecting quantitative data -- 9. Tools for collecting qualitative data -- 10. Building your research team -- 11. In the field -- 12. Analyzing quantitative data -- 13. Analyzing qualitative data -- 14. From research to action -- Appendix 1. The WHO Violence Against Women Instrument -- Appendix 2. Training exercises for interviewers -- Appendix 3. Suggested resources.
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  • Resilience in aging 2011, Springer
    Resilience: definitions, ambiguities, and applications -- Successful aging and resilience: applications for public health and health care -- Resilience and personality disorders in older age -- What do we know about resilience in older adults?: an exploration of some facts, factors, and facets -- Psychological resilience -- Physiological resilience -- Using the arts to promote resiliency among persons with dementia and their caregivers -- Promoting worker resilience over the lifecourse -- Resilience in aging: cultural and ethnic perspectives -- Civic engagement: policies and programs to support a resilient aging society -- Strengthened by the spirit: religion, spirituality, and resilience through adulthood and aging -- Resilience in chronic illness -- The relationship between resilience and motivation -- The association between resilience and survival among Chinese elderly -- Fostering resilience in dementia through narratives: contributions of multimedia technologies -- Building resilience in mild cognitive impairment and early-stage dementia: innovative approaches to intervention and outcome evaluation -- African-American caregivers finding resilience through faith -- The age-friendly New York City project: an environmental intervention to increase aging resilience -- Promoting resilience in small-scale, homelike residential care settings for older people with dementia: experiences from the Netherlands and the United States -- A geriatric mobile crisis response team: a resilience-promoting program to meet the mental health needs of community-residing older people -- Optimizing resilience in the 21st century -- Resilience in the workplace: job conditions that buffer negative attitudes toward older workers.
  • (Publisher-supplied data) Historically, the diagnosis of deafness in a child has been closely associated with profound disability, including such typical outcomes as unmet potential and a life of isolation. A major shift away from this negative view has led to improved prospects for deaf children. Resilience in Deaf Children emphasizes not only the capability of deaf individuals to withstand adversity, but also their positive adaptation through interactions with parents, peers, school, and community. In this engaging volume, leading researchers and professionals pay particular attention to such issues as attachment, self-concept, and social competence, which are crucial to the development of all young people. In addition, the volume offers strategies for family members, professionals, and others for promoting the well-being of deaf children and youth. Coverage includes: Attachment formation among deaf infants and their primary caregivers.Deaf parents as sources of positive development and resilience for deaf infants.Enhancing resilience to mental health disorders in deaf school children.Strength-based guidelines for improving the developmental environments of deaf children and youth.Community cultural wealth and deaf adolescents resilience.Self-efficacy in the management of anticipated work-family conflict as a resilience factor among young deaf adults.Resilience in Deaf Children is essential reading for researchers, clinicians, and graduate students in clinical child, school, and developmental psychology as well as for allied researchers and professionals in such disciplines as school counseling, occupational therapy, and social work.
  • "Resistance training is a form of strength training in which each effort is performed against a specific, opposing force generated by resistance. Increasing evidence-based research highlights the importance of not only aerobic exercise, but resistance training in the prevention, management, and treatment of many chronic conditions. This book presents research on the benefits of resistance training for chronic diseases/disorders. Chapters cover resistance training to treat cardiovascular disease, metabolic diseases, cancer, orthopedic diseases, and neuromuscular disorders"--Provided by publisher.
  • Resistant hypertension 2013, Springer
    A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists. Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becomes more elderly and heavier. While the prognosis of resistant hypertension is unknown, cardiovascular risk is undoubtedly increased since patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors. This volume, compiled by a panel of world-renowned experts, offers a comprehensive exploration of resistant hypertension, covering epidemiology, complex diagnostic aspects, and the therapeutic options currently available, with due attention to overall treatment strategies. New therapeutic agents and procedures, such as renal denervation and baroreceptor stimulation, are also described. In addition, the book addresses the economic aspects of resistant hypertension and the role of the different professional figures, from GPs to hypertension specialists, in dealing with it.
  • An approach to ethical dilemmas in patient care -- Overview of ethical guidelines -- Informed consent -- Promoting the patient's best interests -- Confidentiality -- Avoiding deception and nondisclosure -- Keeping promises -- An approach to decisions about clinical interventions -- Futile interventions -- Decision-making capacity -- Refusal of treatment by competent, informed patients -- Standards for decisions when patients lack decision-making capacity -- Surrogate decision making -- Persistent disagreements over care -- Confusing ethical distinctions -- Ethics committees and case consultations -- Do not attempt resuscitation orders -- Tube and intravenous feedings -- Physician-assisted suicide and active euthanasia -- The persistent vegetative state -- Determination of death -- Legal rulings on life-sustaining interventions -- Overview of the doctor-patient relationship -- Refusal to care for patients -- Gifts from patients to physicians -- Sexual contact between physicians and patients -- Secret information about patients -- Clinical research -- Overview of conflicts of interest -- Bedside rationing of health care -- Incentives for physicians to increase services -- Incentives for physicians to decrease services -- Gifts from drug companies -- Disclosing errors -- Impaired colleagues -- Ethical dilemmas students and house staff face -- Ethical issues in pediatrics -- Ethical issues in surgery -- Ethical issues in obstetrics and gynecology -- Ethical issues in psychiatry -- Ethical issues in organ transplantation -- Testing for genetic conditions -- Ethical issues in public health emergencies.
  • Section I. Fundamentals of clinical ethics -- An approach to ethical dilemmas in patient care -- Overview of ethical guidelines -- Informed consent -- Promoting the patient's best interests -- Confidentiality -- Avoiding deception and nondisclosure -- Keeping promises -- Section II. Shared decision making -- An approach to decisions about clinical interventions -- Futile interventions -- Decision-making capacity -- Refusal of treatment by competent, informed patients -- Standards for decisions when patients lack decision-making capacity -- Surrogate decision making -- Persistent disagreements over care -- Section III. Decisions about life-sustaining interventions -- Confusing ethical distinctions -- Ethics consultations and ethics committees -- Do not attempt resuscitation orders -- Tube and intravenous feedings -- Physician-assisted suicide and active euthanasia -- The persistent vegetative state -- Determination of death -- Legal rulings on life-sustaining interventions -- Section IV. The doctor-patient relationship -- Overview of the doctor-patient relationship -- Refusal to care for patients -- Gifts from patients to physicians -- Sexual contact between physicians and patients -- Secret information about patients -- Clinical research -- Section V. Conflicts of interest -- Overview of conflicts of interest -- Bedside rationing of health care -- Incentives for physicians to increase services -- Measures to control health care costs -- Gifts from drug companies -- Disclosing errors -- Impaired colleagues -- Ethical dilemmas students and house staff face -- Section VI. Ethical issues in clinical specialties -- Ethical issues in pediatrics -- Ethical issues in surgery -- Ethical issues in obstetrics and gynecology -- Ethical issues in psychiatry -- Ethical issues in organ transplantation -- Ethical issues in genomic medicine -- Ethical issues in public health emergencies -- Ethical issues in cross-cultural care.
  • "Every day clinicians encounter ethical dilemmas that have a direct impact on patient care. This timely Fourth Edition will give you expert guidance in approaching a wide range of ethical dilemmas and developing an action plan even when competing points of view have equal merit. Most chapters include real-life sample cases that the author walks through, discussing the salient issues and how to approach them." "This useful resource is a must-read for medical students and practicing professionals at every level of experience!"--BOOK JACKET.
  • Resorcinol 2005, Springer
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    Full text print version of RDA offers a snapshot that serves as an offline access point to RDA.
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    Introduction to patient assessment / Robert L. Wilkins, Philip M. Gold -- Introduction to respiratory failure / Robert L. Wilkins, James R. Dexter -- Asthma / Robert L. Wilkins, Philip M. Gold -- Chronic obstructive pulmonary disease / Robert L. Wilkins, Philip M. Gold -- Cystic fibrosis / N. Lennard Specht -- Hemodynamic monitoring and shock / Robert L. Wilkins, James R. Dexter -- Pulmonary thromboembolic disease / James R. Dexter -- Heart failure / Arthur B. Marshak, George H. Hicks -- Smoke inhalation injury and burns / George H. Hicks, Carl A. Eckrode -- Near drowning / William F. Galvin -- Acute respiratory distress syndrome / Robert L. Wilkins, James R. Dexter -- Chest trauma / George H. Hicks, Carl A. Eckrode -- Postoperative atelectasis / Thomas P. Malinowski -- Interstitial lung disease / N. Lennard Specht -- Neuromuscular diseases / N. Lennard Specht, Rebekah Bartos Specht -- Bacterial pneumonia / Robert L. Wilkins, James R. Dexter -- Pneumonia in the immunocompromised patient / Philip M. Gold, N. Lennard Specht -- Sleep disordered breathing / Enrique Gil -- Tuberculosis / James R. Dexter, Robert L. Wilkins -- Lung cancer / Gregory A.B. Cheek -- Appendix A: Normal laboratory values -- Appendix B: GOLD standards for diagnosing and treating patients with COPD -- Appendix C: Websites useful for learning information about the diagnosis and treatment of lung diseases.
  • Respiratory muscle training 2013, ScienceDirect
    Respiratory Muscle Training: theory and practice is the world's first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts - theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge - and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. Introductory overviews of respiratory and exercise physiology, as well as training theory Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation Evidence-based guidance on the implementation of inspiratory muscle resistance training Over 150 functional exercises that incorporate a breathing challenge www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec's RMT exercise module (via www.physiotec.ca)
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    Structure and function: how the architecture of the lung subserves its function -- Ventilation: how gas gets to the alveoli -- Diffusion: how gas gets across the blood-gas barrier -- Blood flow and metabolism: how the pulmonary circulation removes gas from the lung and alters some metabolites -- Ventilation-perfusion relationships: how matching of gas and blood determines gas exchange -- Gas transport by the blood: how gases are moved to the peripheral tissues -- Mechanics of breathing: how the lung is supported and moved -- Control of ventilation: how gas exchange is regulated -- Respiratory system under stress: how gas exchange is accomplished during exercise, at low and high pressures, and at birth -- Tests of pulmonary function: how respiratory physiology is applied to measure lung function.
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  • Respiratory physiology -- Disorders of the pediatric chest -- Respiratory monitoring -- Bronchoscopy in the pediatric intensive care unit -- Acute lung injury and acute respiratory distress syndrome -- Mechanical ventilation -- Ventilator-induced lung injury -- Prone positioning -- High-frequency oscillatory ventilation -- Pulmonary surfactant: biology and therapy -- Nitric oxide -- Extracorporeal life support for children with acute respiratory failure -- Diseases of the upper respiratory tract -- Congenital airway and respiratory tract anomalies -- Status asthmaticus -- Bronchiolitis -- Pneumonia and empyema -- Pediatric lung transplantation -- Neuromuscular respiratory failure -- Diseases of the pulmonary vascular system.
  • Respiratory tract infections Lane Catalog record
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  • A health-care provider is likely to be the first professional contact for survivors of intimate partner violence or sexual assault. Evidence suggests that women who have been subjected to violence seek health care more often than non-abused women, even if they do not disclose the associated violence. They also identify health-care providers as the professionals they would most trust with disclosure of abuse. These guidelines are an unprecedented effort to equip healthcare providers with evidence-based guidance as to how to respond to intimate partner violence and sexual violence against women. They also provide advice for policy makers, encouraging better coordination and funding of services, and greater attention to responding to sexual violence and partner violence within training programmes for health care providers. The guidelines are based on systematic reviews of the evidence, and cover: 1. identification and clinical care for intimate partner violence 2. clinical care for sexual assault 3. training relating to intimate partner violence and sexual assault against women 4. policy and programmatic approaches to delivering services 5. mandatory reporting of intimate partner violence. The guidelines aim to raise awareness of violence against women among health-care providers and policy-makers, so that they better understand the need for an appropriate health-sector response. They provide standards that can form the basis for national guidelines, and for integrating these issues into health-care provider education.
  • Scientific research and ethics -- Ethical decision making -- Data acquisition and management -- Mentoring and collaboration -- Collaboration between academia and private industry -- Authorship -- Publication and peer review -- Misconduct in research -- Intellectual property -- Conflicts of interest and scientific objectivity -- The use of animals in research -- The protection of human subjects in research -- Protecting vulnerable human subjects in research -- Genetics, cloning, and stem cell research -- International research.
  • RESTful.NET. 1st ed. SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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  • Resuscitation 2014, Springer
    Resuscitation is a two-stage process comprising the achievement/maintenance of spontaneous circulation and post-resuscitation management. The approach is complex and multifaceted and entails the integration of new physiological insights, pharmacological options, and technological advances. The purpose of this volume, written by top experts in the field, is to promote, share, and disseminate new advances in resuscitation and post-resuscitation care. The issues addressed are wide ranging and of great topical interest or controversy. They include priorities of intervention, quality of resuscitation, use of mechanical supports, new defibrillation strategies, prevention of organ damage, strategies in cases of sudden cardiac death, new pharmacological treatments, and post-resuscitation care, including temperature management and prediction and improvement of outcome after cardiac arrest. Particular attention is devoted to up-to-date evidence from the most recent experimental and clinical trials on resuscitation science and to gold standard evidence-based resuscitation and post-resuscitation treatments and interventions. In addition, organizational models and integrated care systems for trauma are considered, and critical care education and the process of guideline development are reviewed.
  • Emergency Medical Services for Children / Derek S. Wheeler and Tom LeMaster -- Pediatric Cardiopulmonary Resuscitation / Vinay M. Nadkarni and Robert A. Berg -- Supplemental Oxygen and Bag-Valve-Mask Ventilation / Patricia Abboud, Jennifer Raake, and Derek S. Wheeler -- Assessment and Management of the Pediatric Airway / Derek S. Wheeler, James P. Spaeth, Renuka Mehta, Suriyanarayana P. Hariprakash, and Peter N. Cox -- Vascular Access / Jennifer Kaplan and Richard J. Brilli -- Shock: An Overview / Joseph A. Carcillo, Derek S. Wheeler, Neil W. Kooy, and Thomas P. Shanley -- Acute Respiratory Failure / Jennifer L. Turi and Ira M. Cheifetz -- Pediatric Transport Medicine / Derek S. Wheeler and W. Bradley Poss -- Withdrawal of Life Support / Kathleen L. Meert and Ashok P. Sarnaik -- Brain Death / Sam D. Shemie -- The Pathophysiology of Brain Death and Care of the Potential Organ Donor / Sam D. Shemie.
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    What is heart failure and what are the treatment options? Complex questions / Jonathan Sackner-Bernstein -- Cardiac resynchronization therapy / David L. Hayes -- Electrocardiogram interpretation with biventricular pacing devices / Samuel J. Asirvatham -- Biventricular device implantation / Samuel J. Asirvatham -- Optimization of biventricular devices / Samuel J. Asirvatham, David L. Hayes -- What echocardiography may offer cardiac resynchronization therapy / Theodore P. Abraham -- Implantable defibrillators and combined ICD-resynchronization therapy in patients with heart failure / Paul J. Wang, David L. Hayes -- Future of cardiac resynchronization / David L. Hayes ... [et al.].
  • Explanations, philosophy and theory in health inequalities research: towards a critical realist approach -- Values and social epidemiologic research -- Population-based data and community empowerment -- Differences that matter -- Context -- Place-based stress and chronic disease: a systems view of environmental determinants -- How goes the neighbourhood? Rethinking neighbourhoods and health research in social epidemiology -- Application of two schools of social theory to neighbourhood, place and health research -- Locating politics in social epidemiology -- Research tools in action -- Structural violence and structural vulnerability within the risk environment: theoretical and methodological perspectives for a social epidemiology of HIV risk among injection drug users and sex workers -- Realist review methods for complex health problems -- Addressing health equalities in social epidemiology: learning from evaluation(s) -- Making a difference -- Knowledge translation and social epidemiology: taking power, politics and values seriously -- Community-academic partnerships and social change -- Producing more relevant evidence: applying a social epidemiology research agenda to public health practice.
  • Retina. 4th ed. v. 1-3, 2006.
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    v. 1. Basic science, inherited retinal disease, and tumors -- v. 2. Medical retina -- v. 3. Surgical retina.
  • 1.Cellular and molecular mechanisms of retinal angiogenesis /M.A. Behzadian et. al --2.Animal models of choroidal neovascularization /M.L. Clark, J.A. Fowler, and J.S. Penn --3.Rodent models of oxygen-induced retinopathy /S.E. Yanni, G.W. McCollum, and J.S. Penn --4.Animal models of diabetic retinopathy /T.S. Kern --5.Neovascularization in models of branch retinal vein occlusion /R.P. Danis and D.P. Bingaman --6.Vasculogenesis and angiogenesis in formation of the human retinal vasculature /T. Chan-Ling --7.IGF-1 and retinopathy /L.E.H. Smith --8.Hypoxia and retinal neovascularization /B.A. Berkowitz --9.Hypoxia inducible Factor-1 and VEGF induction /A. Madan --10.The role of protein kinase C in diabetic retinal vascular abnormalities /J.K. Sun and G.L. King --11.Eph receptor tyrosine kinases: modulators of angiogenesis /J. Chen, D. Brantley-Siders, and J.S. Penn --12.Adenosine in retinal vasculogenesis and angiogenesis in oxygen-induced retinopathy /G.A. Lutty and D.S. McLeod --13.The regulation of retinal angiogenesis by cyclooxygenase and the prostanoids /G.W. McCollum and J.S. Penn --14.Extracellular proteinases in ocular angiogenesis /A. Das and P.G. McGuire --15.Oxygen-independent angiogenic stimuli /J.M. Holmes, D.A. Leske, and W.L. Lanier --16.Growth factor synergy in angiogenesis /A.V. Ljubimov --17.Pigment epithelium derived factor and angiogenesis /J. Amaral and S.P. Becerra --18.Circulating endothelial progenitor cells and adult vasculogenesis /S. Caballero, N. Sengupta, L.C. Shaw, and M.B. Grant --19.Retinopathy of prematurity /D.L. Phelps --20.Angiogenesis in sickle cell retinopathy /G.A. Lutty and D.S. McLeod --21.Diabetic retinopathy /R.N. Frank --22.Systems for drug delivery to the posterior segment of the eye /A.L. Weiner and D.A. Marsh --23.Novel therapeutic strategies for posterior segment neovascularization /D.P. Bingaman, X. Gu, A.M. Timmers, and A. Davis --24.Choroidal neovascularization in age-related macular degeneration- from mice to man /L. Berglin.
  • This book presents the current information on retinal and choroidal manifestations of systemic diseases from leading experts in the field and is intended for ophthalmologists, retina specialists, uveitis and ocular oncology specialists. The topics discussed in this book are not all inclusive, but include retinal and choroidal manifestations of AIDS, diffuse unilateral subacute neuroretinitis (DUSN), posterior pole manifestations of cycticercosis, toxocariasis, tuberculosis, toxoplasmosis, viral diseases, fungal diseases, endogenous endophthalmitis, sarcoidosis, diabetic retinopathy, and many more.
  • Retinal degenerations 2007, Springer
    Coping with retinal degeneration : a patient's view / Gordon Cousins and James Cape -- Epidemiology of age-related macular degeneration early in the 21st century / Jie Jin Wang, Paul Mitchell, and Ronald Klein -- Leber congenital amaurosis : a hereditary childhood form of blindness and a model to elucidate retinal physiology and development / Robert K. Koenekoop -- Macular degeneration : aging changes and novel therapies / Peter E. Liggett and Alejandro J. Lavaque -- Stargardt disease : from gene discovery to therapy / Rando Allikmets -- X-linked juvenile retinoschisis / Bernhard H. F. Weber and Ulrich Kellner -- Retinal degeneration in Usher syndrome / David S. Williams -- Mouse models of retinitis pigmentosa / Bo Chang ... [et al.] -- The impact of diabetes on neuronal, glial, and vascular cells of the retina : implications for the pathogenesis of diabetic retinopathy / Sylvia B. Smith -- Statins and age-related maculopathy / Gerald McGwin, Jr. and Cynthia Owsley -- The role of drusen in macular degeneration and new methods of quantification / R. Theodore Smith and Umer F. Ahmad -- RPE lipofuscin : formation, properites, and relevance to retinal degeneration / Janet R. Sparrow -- Genetic modifiers that affect phenotypic expression of retinal diseases / Malia M. Edwards ... [et al.] -- X-linked retinal dystrophies and microtubular functions within the retina / Alan F. Wright and Xinhua Shu -- Synaptic remodeling in retinal degeneration / You-Wei Peng and Fulton Wong --On the suppression of photoreceptor cell death in retinitis pigmentosa / Fiona Kernan ... [et al.] -- Cell-based therapies to restrict the progress of photoreceptor degeneration / Raymond D. Lund and Shaomei Wang -- Current status of IPE transplantation and its potential as a cell-based therapy for age-related macular degeneration and retinal dystrophies / Makoto Tamai -- Recent results in retinal transplantation give hope for restoring vision / Robert B. Aramant, Norman D. Radtke, and Magdalene J. Seiler -- Stem cells and retinal transplantation / Joanne Yau ... [et al.] -- Application of encapsulated cell technology for retinal degenerative diseases / Weng Tao and Rong Wen -- Effective treatment for the canine RPE65 null mutation, a hereditary retinal dystrophy comparable to human Leber's congenital amaurosis / Kristina Narfström, Gregory E. Tullis, and Mathias Seeliger -- The use of neuroprotective factors in retinal degenerations / Joyce Tombran-Tink and Colin J. Barnstable -- Carbonic anhydrase inhibitors as a possible therapy for RP17, an autosomal dominant retinitis pigmentosa associated with the R14W mutation, apoptosis, and the unfolded protein response / George Rebello, Jacquie Greenberg, and Raj Ramesar -- Macular Degeneration- an addendum / Joyce Tombran-Tink and Colin J. Barnstable.
  • Part 1. AMD: Basic Mechanisms, Inflammation and Immunity -- Part 2. Neuroprotection, Drugs and Novel Protective Therapies -- Part 3. Gene Therapy -- Part 4. Blood Vessels, Angiogenesis, and Neovascularization -- Part 5. Genotype/Phenotype -- Part 6. New Animal Models of Retinal Degeneration -- Part 7. Analysis of Retinal Degeneration by Imaging and Functional Testing -- Part 8. Mechanisms of Retinal Degeneration -- Part 9. Retinal Development, Physiology, Cell and Molecular Biology.
  • Molecular genetics and candidate genes -- Diagnostic, clinical, cytopathological, and physiologic aspects of retinal degeneration -- Animal models of retinal degeneration -- Gene therapy and neuroprotection -- Usher syndrome -- Stem cells, transplantation, and retinal repair -- Induced retinal degenerations.
  • "This book will contain the proceedings of the XV International Symposium on Retinal Degeneration (RD2012). A majority of those who will speak and present posters at the meeting will contribute to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium will focus on the exciting new developments aimed at understanding these diseases and providing therapies for them. Since most major scientists in the field of retinal degenerations attend the biennial RD Symposia, they are known by most as the “best” and “most important” meetings in the field. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy."--Publisher's website.
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    Sect. IImaging modalities: basic principles and interpretation --Sect. IIMacular diseases --Sect. IIIRetinal vascular diseases --Sect. IVInflammatory and infectious diseases --Sect. VOther retinal diseases --Sect. VITumors --Sect. VIIOptic nerve disorders.
  • Retinal vascular disease 2007, Springer
    I. Pathogenesis of retinal vascular disease -- 1 Functional anatomy, fine structure and basic pathology -- 2 Retinal vascular development -- 3 Retinal angiogenesis and growth factors -- 4 Hematopoietic stem cells in vascular development and ocular neovascularization -- 5 Inflammation as a stimulus for vascular leakage and proliferation -- 6 The neuronal influence on retinal vascular pathology -- 7 Hypoxia in the pathogenesis of retinal disease -- 8 Blood retinal barrier -- 9 Retinal blood flow -- 10 Genetic approach to retinal vascular disease -- II. General concepts in the diagnosis and treatment of retinal vascular disease -- 11 A practical guide to fluorescein angiography -- 12 Optical coherence tomography in the diagnosis of retinal vascular disease -- 13 General concepts in laser treatment for retinal vascular disease -- 14 The role of photodynamic therapy in retinal vascular disease -- 15 Cryosurgery in retinal vascular disease -- 16 Vitrectomy in retinal vascular disease: surgical principles -- 17 Treatment of rubeotic secondary glaucoma -- 18 Intravitreal injections: guidelines to minimize the risk of endophthalmitis --III. Pathology, clinical course and treatment of retinal vascular diseases -- 19 Grading of diabetic retinopathy -- 20 Retinopathy of prematurity -- 21 Vascular occlusive disease -- 22 Vascular abnormalities -- 23 Vasculopathy after treatment of choroidal melanoma -- 24 Vasculopathies with acute systemic diseases -- 25 Inflammatory vascular disease -- 26 Hypertensive retinopathies -- 27 Sickle cell retinopathy and hemoglobinopathies -- 28 Vascular tumors of the retina.
  • Retinal vein occlusions 2012, Springer
    Anatomy and Pathologic Anatomy of Retinal Vein Occlusions --Pathophysiology of Retinal Vein Occlusions --Genetics of Retinal Vein Occlusions --Classification of Retinal Vein Occlusion --Epidemiology of Retinal Vein Occlusions --Systemic and Ocular Associations of Retinal Vein Occlusions --The Clinical Picture and Natural History of Retinal Vein Occlusions --Ancillary Testing in the Management of Retinal Vein Occlusions --Ischemia and Retinal Vein Occlusions --Posterior Segment Neovascularization in Retinal Vein Occlusion --Anterior Segment Neovascularization in Retinal Vein Occlusion --Macular Edema in Retinal Vein Occlusion --Treatment of Retinal Vein Occlusions --Retinal Vein Occlusions in the Young --Failed and Unadopted Treatments for Retinal Vein Occlusions --Case Studies in Retinal Vein Occlusion.
  • Retinoblastoma 2010, Springer
  • Retinoblastoma 2013, Future Med
    Clinical advances and emerging treatment strategies / Timothy G. Murray -- Laboratory discoveries in retinoblastoma / Samuel K. Houston & Timothy G. Murray -- Incidence, prevalence and epidemiology / Ricardo Garza & Dan S. Gombos -- Clinical features and diagnosis of retinoblastoma / Matthew A. Cunningham & H. Culver Boldt -- Genetics of retinoblastoma and genetic counseling / Jessica Moline & Arun D. Singh -- Anesthetic considerations for children with retinoblastoma / Jacqueline Tutiven & Michael M. Vigoda -- Radiation therapy in retinoblastoma / Shiv C. Desai, Derek M. Isrow & Arnold M. Markoe -- Chemotherapy in the management of retinoblastoma / Ziad A. Khatib & Wenliang Geng -- Retinoblastoma treatment / Samuel K. Houston & Timothy G. Murray -- Treatment of extraocular and metastatic retinoblastoma / Ira J. Dunkel & Guillermo L. Chantada -- Second malignancies and other long-term effects in retinoblastoma survivors / Annette C. Moll, Jennifer van Dijk, Machteld I. Bosscha, Charlotte J. Dommering, Pim de Graaf, W. Arjenne Kors & Flora E. van Leeuwen -- Visual rehabilitation for retinoblastoma / D/ Wilkin Parke & Aaron Gold -- Retinoblastoma in the developing world / Vikas Khetan, Sabyasachi Sengupta, Fariooz P. Manjandavida & Santosh G. Honavar -- Index.
  • Anatomical Aspects of the Extra- and Retroperitoneal Space / Ahmed E. Ghazi and Jean V. Joseph -- Essential Instruments in Laparoscopic and Robotic Surgery / Ty T. Higuchi and Matthew T. Gettman -- Upper Tract Retroperitoneal Access Techniques / Ahmed E. Ghazi and Jean V. Joseph -- Laparoscopic and Robotic Adrenalectomy / Edmund Y. Ko, Richard T. Schlinkert and Mitchell R. Humphreys -- Retroperitoneoscopic Simple and Radical Nephrectomy / Guillaume Ploussard, Andras Hoznek, Laurent Salomon, Claude C. Abbou and Alexandre de la Taille -- Laparoscopic and Robotic Partial Nephrectomy / Lori M. Dulabon and Michael D. Stifelman -- Retroperitoneal Robotic Partial Nephrectomy / James R. Porter -- Laparoscopic and Robotic Mid and Distal Ureteral Reconstructive Surgery / Alireza Moinzadeh -- Robot-Assisted Laparoscopic Nephroureterectomy / Sijo J. Parekattil, Hany N. Atalah and Li-Ming Su -- Laparoscopic Pelvic Lymphadenectomy in Prostate Cancer / Evangelos Liatsikos, Minh Do, Panagiotis Kallidonis, Iason Kyriazis and Alan McNeil, et al. -- Laparoscopic Simple Prostatectomy / Xavier Cathelineau, Rafael E. Sanchez-Salas, Eric Barret, Francois Rozet and Marc Galiano, et al. -- Extraperitoneal Laparoscopic Radical Prostatectomy / Sarah P. Psutka and Douglas M. Dahl -- Robot-Assisted Extraperitoneal Laparoscopic Prostatectomy / Thomas T. Hoang, Satya B. Allaparthi and Ingolf A. Tuerk -- Laparoendoscopic Single-Site Retroperitoneal Surgery / Michael A. White and Jihad H. Kaouk -- On the Horizon / Jean V. Joseph and Hitendra R. H. Patel.
  • Retroviral proteases ScienceDirect
  • Structural studies on HIV reverse transcriptase related to drug discovery / David K. Stammers and Jingshan Ren -- Zidovudine, lamivudine, and abacavir / Monica Carten and Harold Kessler -- Stavudine, didanosine, and zalcitabine / Gail Skowron, Sapna Chowdhry and Michael R. Stevens -- Emtricitabine / Gail Skowron, Jeffrey Bratberg and Rudi Pauwels -- Nucleotide analogs / Craig J. Hoesley -- Resistance to nucleoside and nucleotide reverse transcriptase inhibitors / Nancy Shulman and Mark Winters -- Pharmacokinetics of reverse transcriptase inhibitors / Patrick Hoggard ... [et al.] -- Peripheral neuropathy associated with nucleoside reverse transcriptase inhibitor therapy / Bruce A. Cohen and Russell Bartt -- Mitochondrial dysfunction and nucleoside reverse transcriptase inhibitor therapy: a pathophysiological perspective / William Lewis -- Mitochondrial toxicity and lipodystrophy / Grace McComsey -- Nevirapine / David Asmuth and Richard Pollard -- Efavirenz / Graeme J. Moyle and Brian Conway -- Delavirdine / Brian Conway -- Resistance to non-nucleoside reverse transcriptase inhibitors / F. Ramzi Asfour and Richard Haubrich -- Vertical transmission of HIV and therapeutic interventions / Susan Cu-Uvin, Arlene Bardeguez and Carla Chibwesha -- New reverse transcriptase inhibitors in development / Rudi Pauwels -- Antiretroviral drugs for millions / Allan Ronald, Ellie Katabira and Merle Sande.
  • Chapter 1. The Physiologic Basis of Homeostasis -- Section. Amplification Systems -- Chapter 2. Nervous System -- Chapter 3. Immune System -- Chapter 4. Endocrine System.
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  • Review of medical microbiology and immunology 2012 (12th ed.), AccessMedicine
  • Review of medical physiology 2012 (24th ed.), AccessMedicine
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    Basic sciences / Mark R. Brinker, Daniel P. O'Connor -- Pediatric orthopaedics / Todd A. Milbrandt, Daniel J. Sucato -- Sports medicine / Joshua A. Baumfeld, Jennifer A. Hart, Mark D. Miller -- Adult reconstruction / Edward J. McPherson -- Disorders of the foot and ankle / Gregory J. Roehrig, MD ... [et al.] -- Hand, upper extremity, and microvascular / Lance M. Brunton, A. Bobby Chhabra -- Spine / William C. Lauerman, Bradley Graw -- Pathology / Frank J. Frassica, Deborah A. Frassica, Edward F. McCarthy -- Rehabilitation: gait, amputations, prosthetics, orthotics / Frank A. Gottschalk -- Trauma / James P. Stannard ... [et al.] -- Anatomy / Franklin D. Shuler -- Principles of practice and statistics / S. Raymond Golish, Mark DeHart.
  • X-ray production -- X-ray interactions -- Projection radiography I -- Projection radiography II -- Computed tomography -- Image quality -- Radiobiology/patient dosimetry -- Radiation protection -- Nuclear medicine -- Ultrasound -- Magnetic resonance.
  • Review of rheumatology 2012, Springer
    The Musculoskeletal System -- Mediators of Rheumatic Pathology -- Immunity -- Genetics -- Rheumatoid Arthritis -- Psoriatic Arthritis -- Systemic Lupus Erythematosus (SLE) -- Arthritis Associated with Calcium-Containing Crystals -- Gout -- Vasculitides -- Systemic Sclerosis and Related Syndromes -- Sjögren's Syndrome -- Behcet's Disease -- Relapsing Polychondritis -- Antiphospholipid Syndrome -- Adult Still's Disease -- Therapeutic Injections for Rheumatic Diseases -- Nonsteroidal Anti-inflammatory Drugs -- Corticosteroids -- Disease-Modifying Antirheumatic Drugs -- Cytotoxic and Immunoregulatory Agents -- Biologic Agents -- Osteoporosis -- Metabolic Bone Disorders -- Paget's Disease of Bone -- Osteonecrosis -- Hypertrophic Osteoarthropathy -- Storage and Deposition Diseases -- Amyloidoses -- The Autoinflammatory Diseases.
  • Review of surgery 2006, Springer
  • v. 1. Infectious diseases.
  • Ch. 1. DT40 gene disruptions: a how-to for the design and the construction of targeting vectors / Hiroshi Arakawa and Jean-Marie Buerstedde -- Ch. 2. Immunoglobulin gene conversion or hypermutation: That's the question / Jean-Marie Buerstedde and Hiroshi Arakawa -- Ch. 3. Genome resources for the DT40 community / Randolph B Caldwell and Andrzej M. Kierzek -- Ch. 4. Chromosome engineering in DT40 cells and mammalian centromere function / William R.A. Brown ... [et al.] -- Ch. 5. Function of recQ family helicase in genome stability / Masayuki Seki, Shusuke Tada and Takemi Enomoto -- Ch. 6. Genetic analysis of apoptotic execution / Sandrine Ruchaud ... [et al.] -- Ch. 7. The DT40 system as a tool for analyzing kinetochore assembly / Masahiro Okada, Tesuya Hori and Tatsuo Fukagawa -- Ch. 8. Analysing the DNA damage and replication checkpoints in DT40 cells / Michael D Rainey, George Zachos, and David AF Gillespie -- Ch. 9. Using DT40 to study clathrin function / Frank R. Wettey and Antony P. Jackson -- Ch. 10. Genetic analysis OF B cell signaling / Hisaaki Shinohara and Tomohiro Kurosaki --Ch. 11. DT40 mutants: a model to study transcriptional regulation of B cell development and function / Jukka Alinikula, Olli Lassila and Kalle-Pekka Nera -- Ch. 12. Transcription and RNA processing factors play complex roles IN DT40 cells / Stephanie Bush and James L. Manley -- Ch. 13. Participation of histones, histone modifying enzymes and histone chaperones in vertebrate cell functions / Hidehiko Kikuchi ... [et al.] -- Ch. 14. Analysis of gene expression, copy number and palindrome formation with a DT40 enriched cDNA Microarray / Paul E. Neima ... [et al.] -- Ch. 15. Analysis of DNA replication damage bypass and its role in immunoglobulin repertoire development / Julian E. Sale, Anna-Laura Ross and Laura J. Simpson -- Ch. 16. The fanconi anemia pathway promotes homologous recombination repair in DT40 cell line / Julian E. Sale, Anna-Laura Ross and Laura J. Simpson -- Ch. 17. Calcium signaling, ion channels and more / Anne-Laure Perraud, Carsten Schmitz, Andrew M. Scharenberg -- Ch. 18. Phenotypic analysis of cellular responses to DNA damage / Helfrid Hochegger and Shunichu Takeda -- Ch. 19. ATM, a paradigm for a stress-responsive signal transducer in higher vertebrate cells / Ken-ichi Yamamoto, Masahiko Kobayashi and Hiroko Shimizu --METHOD 1. Stable transfection of DT40 / Julian E. Sale -- METHOD 2. Basic cell culture conditions / Huseyin Saribasak and Hiroshi Arakawa -- METHOD 3. Excision of floxed-DNA sequences by transient induction of Mer-Cre-Mer / Hiroshi Arakawa -- METHOD 4. Immunoglobulin gene conversion and hypermutation assay by FACS / Hiroshi Arakawa -- METHOD 5. Target screening by PCR / Hiroshi Arakawa -- METHOD 6. Mitotic index determination by flow cytometry / David AF Gillespie and Mark Walker -- METHOD 7. Centrifugal elutriation as a means of cell cycle phase separation and synchronization / David AF Gillespie and Catarina Henriques -- METHOD 8. Preparation of genomic DNA for microarray-based comparative genome hybridization / Robert Kimmel, Amalia Icreverzi, Paul Neiman -- METHOD 9. Analysis of cellular Mg2+ in DT40 cells / Anne-Laure Perraud, Carsten Schmitz, Andrew M. Scharenberg -- METHOD 10. Transient transfection of DT40 / Roger Franklin & Julian E. Sale -- METHOD 11. Retroviral transduction of DT40 / Felix Randow & Julian E. Sale -- METHOD 12. Colony survival assay / Laura. J. Simpson & Julian E. Sale -- METHOD 13. Subcloning DT40 by limiting dilution / Jean-Marie Buerstedde --METHOD 14. Subnuclear immunofluorescence / Dávid Szüts & Julian E. Sale -- METHOD 15. Sister chromatid exchange assay / Laura J. Simpson & Julian E. Sale -- METHOD 16. 2D cell cycle analysis / Roger Franklin & Julian E. Sale -- METHOD 17. Purification of tap-tagged proteins by two-step pull down from DT40 cells / Hiroyuki Kitao and Minoru Takata -- METHOD 18. Synchronization of cells / Eiichiro Sonoda -- METHOD 19. Tranfection of DT40 cells / Huseyin Saribasak and Hiroshi Arakawa -- METHOD 20. Luciferase reporter assay / Frank R. Wettey and Antony P. Jackson -- METHOD 21. Indirect immunofluorescence microscopy / Frank R. Wettey and Antony P. Jackson -- METHOD 22. Quantification of receptor-mediated endocytosis / Frank R. Wettey and Antony P. Jackson -- METHOD 23. Measurement of DNA synthesis and strand breaks using alkaline sucrose density gradient centrifugation / Kouichi Yamada and Jun Takezawa -- METHOD 24. Fractionation of nuclear and cytoplasmic proteins from DT40 cell lines / Yan-Dong Wang and Randolph B Caldwell.
  • Although anterior cruciate ligament (ACL) reconstruction has a high success rate, a substantial number of patients are left with unsatisfactory results. Revision ACL Reconstruction: Indications and Technique provides detailed strategies for planning and executing revision ACL reconstructions. Concise chapters by a leading group of international orthopedic surgeons cover the diagnosis of failed ACL reconstruction, patient evaluation, preoperative planning for revision ACL surgery, and complex technical considerations.
  • This report is being released in conjunction with the Robert Wood Johnson Foundation's Care About Your Care initiative, which is devoted to improving care transitions when people leave the hospital. It looks at the issue of readmissions in two ways: by the numbers and through the eyes of the people who live them.
  • Rhesus monkey brain. 2nd ed. SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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  • The summary of the published clinical guideline on Rheumatoid arthritis. It links to the published guidance and key documents.
  • Rheumatology in practice 2010, Springer
    The Importance of Rheumatic Diseases, The Satisfaction Of Caring For These Patients -- Pain, Disease and Suffering an Integrated Perspective -- The Structure and Function of the Musculoskeletal System Sources of Pain -- Diagnostic Strategy the Main Syndromes in Rheumatology -- The Standard Enquiry in Rheumatology -- The General Clinical Examination -- Regional Syndromes Neck Pain -- Regional Syndromes The Painful Shoulder -- Regional Syndromes The Elbow And Forearm -- Regional Syndromes the Wrist and Hand -- Regional Syndromes Low Back Pain -- Regional Syndromes The Hip -- Regional Syndromes The Knee -- Regional Syndromes the Foot and Ankle -- Generalized Pain Syndrome Fibromyalgia Osteoarthritis -- Inflammatory Arthritides Diagnostic Strategies -- Monoarthritis -- Chronic, Additive, Symmetrical, Peripheral Polyarthritis -- Chronic, Asymmetrical Oligo- Or Polyarthritis -- Chronic Proximal Oligoarthritis -- Arthritis of the Shoulder and Pelvic Girdles Polymyalgia Rheumatica -- Acute Oligo- or Polyarthritis Febrile Arthritis Arthritis with Mucocutaneous Manifestations -- Inflammatory Low Back Pain -- Systemic Syndromes Connective Tissue Diseases Vasculitis Raynaud's Phenomenon -- Osteoporotic Syndrome Osteoporosis -- Bone Syndrome Bone Diseases -- Rheumatic Symptoms in Children and Adolescents -- Treating Rheumatic Diseases, General Principles -- Drugs Commonly Used in Rheumatic Diseases.
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  • 1. Diagnostic Training and Rheumatology Trees -- 2. Explanations of Figures and Case Reports with Individual Therapeutic Options -- 3. Index of Figures (Fig.) and CS with Syndromes (for Self-assessment) -- Appendix: Index of the Solutions to the Syndromes and Diagnostics (for Rapid Diagnosis).
  • 1. Articular disorders -- 2. Diseases of the spine -- 3. Soft-tissue rheumatism and related disorders -- 4. Regional arthrological and musculoskeletal syndromes -- 5. Paraneoplastic syndromes (PNS) in rheumatology -- 6. Algorithms in articular and musculoskeletal disorders: integrated diagnostic screening program: staged diagnostics -- 7. Algorithms in arthrological and musculoskeletal disorders -- 8. General symptoms (BVAS = maximum of 3 out of 63 points) -- 9. Involvement of connective tissue structures -- 10. System-/organ involvement -- 11. (Auto) immunological phenomena and serological diagnostics -- 12. Treatment-induced and associated conditions and diseases -- 13. Integrated diagnostic screening program staged diagnostics -- 14. Algorithms for connective tissue disease and vasculitis.
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  • Rhinosinusitis 2008, Springer
  • RHO family GTPases 2005, Springer
  • Rho GTPases in cancer 2010, Springer
  • Rhode Island's Civil War hospital SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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    "During the Civil War, Union soldiers and Confederate prisoners convalesced in a general army hospital in Portsmouth Grove, Rhode Island. This study details experiences of those who received and provided care, exploring the barbarities of medicine, daily routine, role of citizens, later adventures of former patients/staff, and final resting places of those who died on the grounds"--Provided by publisher.
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    Structure defines function -- Diversity of cortical functions is provided by inhibition -- Windows on the brain -- A system of rhythms -- Synchronization by oscillation -- The brain's default state -- Perturbation of the default patterns by experience -- The gamma buzz -- Perceptions and actions are brain state-dependent -- Oscillations in the "other cortex" -- Coupling of systems by oscillations -- Tough problems.
  • Ribonuclease P 2010, Springer
    History of RNase P and Overview of Its Catalytic Activity -- The Evolution of RNase P and Its RNA -- Over a Decade of Bacterial Ribonuclease P Modeling -- Structural Studies of Ribonuclease P -- Folding of Bacterial RNase P RNA -- Kinetic Mechanism of Bacterial RNase P -- Roles of Metal Ions in RNase P Catalysis -- Challenges in RNase P Substrate Recognition: Considering the Biological Context -- Archaeal RNase P: A Mosaic of Its Bacterial and Eukaryal Relatives -- Eukaryote RNase P and RNase MRP -- RNase P from Organelles -- Human RNase P and Transcription -- RNase P as a Drug Target -- Ribonuclease P as a Tool.
  • Ribonucleases 2011, Springer
  • Fulltext (pt. B) ScienceDirect
  • Ribosomes 2011, Springer
  • Ribosomes ScienceDirect
  • Ribozymes and siRNA protocols. 2nd ed. 2004, Springer Protocols
  • Ricin and shiga toxins 2012, Springer
    Interaction of Ricin and Shiga Toxins with Ribosomes -- How Ricin and Shiga Toxin Reach the Cytosol of Target Cells: Retrotranslocation from the Endoplasmic Reticulum -- Ricin and Shiga Toxins: Effects on Host Cell Signal Transduction -- Pathogenesis of Shiga-Toxin Producing Escherichia coli -- Shiga Toxin Pathogenesis: Kidney Complications and Renal Failure -- The Induction of Apoptosis by Shiga Toxins and Ricin -- Small-Molecule Inhibitors of Ricin and Shiga Toxins -- Immunity to Ricin: Fundamental Insights into Toxin-Antibody Interactions -- Animal Models of Ricin Toxicosis -- Ricin Vaccine Development.
  • Right heart 2014, Springer
    "This comprehensive book describes the structure, function and imaging of the normal right heart both at rest and under the stresses of high altitude and exercise. It continues with a detailed examination of the pathophysiology and pathobiology of right heart dysfunction, both in experimental models and human disease, including congenital heart disease. Right heart dysfunction caused by pulmonary hypertension is discussed in particular detail. The Right Heart brings together a distinguished group of contributors to discuss the advances in the topic that have occurred over the last few years and provides a concise and up-to-date resource for clinicians by compiling this comprehensive state-of-the-art text on the subject, the Editors have created an indispensable reference for future work by those interested in the cardiopulmonary circuit. This book will appeal to respiratory physicians, cardiologists and intensivists, all of whom will share the Editors' belief that the right heart is fundamental to integrated cardiopulmonary performance."
  • Right start Fulltext
  • Introduction / Massimo Chessa and Alessandro Giamberti -- Anatomy of Tetralogy of Fallot / Carla Frescura and Gaetano Thiene -- Genetics / M. Cristina Digilio, Bruno Dallapiccola and Bruno Marino -- Stem Cells and the Right Ventricle / Luigi Anastasia and Marco Piccoli -- Pathophysiology in Tetralogy of Fallot / Gabriele Egidy Assenza and Michael J. Landzberg -- Tetralogy of Fallot: Late Outcome / Jochen Weil -- Tetralogy of Fallot: the Failing Right Ventricle / Folkert J. Meijboom and Barbara Mulder -- Imaging Evaluation / Claudio Bussadori -- Timing for RVOT Management / Harald Kaemmerer, Andreas Eicken and John Hess -- Percutaneous Pulmonary Valve / Mark S. Turner, Mario Carminati and Philipp Bonhoeffer -- Other Transcatheter Procedures / Massimo Chessa and Gianfranco Butera -- Surgical Pulmonary Valve Implantation / Alessandro Giamberti, Giuseppe Pomè and Alessandro Frigiola -- Other Surgical Procedures / Alessandro Giamberti -- Late Arrhythmias: Current Approaches / Sara Foresti, Maria Cristina Tavera, Pierpaolo Lupo and Riccardo Cappato -- Perioperative Right Ventricular Management / Marco Ranucci.
  • Ringtailed lemur biology 2006, Springer
    The distribution and biogeography of the ringtailed lemur (Lemur catta) in Madagascar / Steven M. Goodman, Soava V. Rakotoarisoa and Lucienne Wilmé -- A preliminary estimate of Lemur catta population density using satellite imagery / Robert W. Sussman ... [et al.] -- Berenty Reserve : a research site in southern Madagascar / Alison Jolly ... [et al.] -- Beza Mahafaly Special Reserve : a research site in southwestern Madagascar / Robert W. Sussman and Joelisoa Ratsirarson -- Plant species fed on by Lemur catta in gallery forests of the southern domain of Madagascar / Bruno Simmen ... [et al.] -- Tamarind recruitment and long-term stability in the gallery forest at Berenty, Madagascar / Kathryn Blumenfeld-Jones ... [et al.] -- Home ranges of ringtailed lemur troops and the density of large trees at Berenty Reserve, Madagascar / Naoki Koyama ... [et al.] -- The influence of tamarind tree quality and quantity on Lemur catta behavior / Anne S. Mertl-Millhollen ... [et al.] -- Feeding competition between introduced Eulemur fulvus and native Lemur catta during the birth season at Berenty Reserve, southern Madagascar / Susan Pinkus, James N.M. Smith and Alison Jolly --Tradition and novelty : Lemur catta feeding strategy on introduced tree species at Berenty Reserve / Takayo Soma -- Diet quality and taste perception of plant secondary metabolites by Lemur catta / B. Simmen ... [et al.] -- Territory as bet-hedging : Lemur catta in a rich forest and an erratic climate / Alison Jolly ... [et al.] -- Resource defense in Lemur catta : the importance of group size / R. Ethan Pride ... [et al.] -- Social changes in a wild population of ringtailed lemurs (Lemur catta) at Berenty, Madagascar / Shinichiro Ichino and Naoki Koyama -- Obsession with agonistic power / Michael. E. Pereira -- Male and female ringtailed lemurs' energetic strategy does not explain female dominance / Hantanirina Rasamimanana ... [et al.] -- Male sociality and integration during the dispersal process in Lemur catta : a case study / Lisa Gould -- Patterns of health, disease, and behavior among wild ringtailed lemurs, Lemur catta: effects of habitat and sex / Michelle L. Sauther ... [et al.] -- Bald lemur syndrome and the miracle tree : alopecia associated with Leucaena leucocephala at Berenty Reserve, Madagascar / Graham C. Crawford ... [et al.] -- Temporal change in tooth size among ringtailed lemurs (Lemur catta) at the Beza Mahafaly Special Reserve, Madagascar : effects of an environmental fluctuation / Frank P. Cuozzo and Michelle L. Sauther.
  • Riot control agents 2004, CRCnetBASE
  • Rise of alchemy in fourteenth-century England SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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    Pt. 1. Alchemy and the occult in English cultural and political life. Introduction : alchemy and the occult in England ; The origins of English alchemy and sources for the study of alchemy in fourteenth-century England -- Pt. 2. The Astrology of the earth : the intellectual impact of alchemy in fourteenth-century England. Alchemy and science and philosophy ; Alchemy and the Church ; The Cultural impact of alchemy -- Pt. 3. The Political significance of alchemy. The accession of Edward III ; Alchemical themes in the kingship of Edward III ; Richard II the magus and boy king ; Richard II and the occult ; Conclusion : the Lancastrian reaction.
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    Reasons for risk adjustment / Lisa I. Iezzoni -- Getting started and defining terms / Lisa I. Iezzoni -- Range of risk factors / Lisa I. Iezzoni -- Windows of observation / Amy K. Rosen and Ann M. Borzecki -- Coded data from administrative sources / Lisa I. Iezzoni -- Clinical data from medical records and health information technologies / Lisa I. Iezzoni -- Data from patient surveys / Lisa I. Iezzoni and Karen Donelan -- Conceptual and practical issues in developing risk adjustment methods / Lisa I. Iezzoni -- Validity and reliability of risk adjustment methods / Lisa I. Iezzoni -- Empirically evaluating risk adjustment models / Michael Shwartz and Arlene S. Ash -- Estimating the effect of an intervention from observational data / Michael Shwartz and Arlene S. Ash -- Comparing outcomes across providers / Arlene S. Ash ... [et al.] -- Risk adjustment in pediatric populations / Karen Kuhlthau, Jeanne Van Cleave, and Timothy G. Ferris -- Risk adjustment for mental health care / Anthony P. Weiss and Mark A. Blais -- Risk adjustment and persons with disabilities / Lisa I. Iezzoni -- Risk adjustment for long-term care / Dan Berlowitz and Orna Intrator -- The role of risk adjustment in managing health care organizations / Jennifer Daley -- Final observations / Lisa I. Iezzoni.
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    Choleragenic Vibrio cholerae 01 and 0139 are the causative agent of cholera, a water-and-food-borne disease with epidemic and pandemic potential. This report focuses on the risk of acquiring cholera from warm-water shrimps in international trade. Shrimp is a very important export product from many developing countries but outbreaks of cholera in these countries can have devastating effects on the international markets for their food products. This volume looks at different approaches for assigning the risk associated with choleragenic V. Cholerae in warm-water shrimp in international trade. Qualitative and quantitative approaches to assessing risk were developed and compared and risk estimates were made using the available and relevant data. --Publisher's description.
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    Vibrio vulnificus is one of three pathogenic Vibrio spp. on which FAO and WHO have undertaken risk assessment work. This pathogen is associated primarily with raw oysters but can occur in a variety of seafood products. As well as causing gastrointestinal illness, V. vulnificus can cause primary septicaemia which is a serious and often fatal disease in individuals with chronic pre-existing conditions. This volume provides an approach for undertaking quantitative risk assessment of V. vulnificus in raw oysters. This risk assessment model was also developed to evaluate the effectiveness of various interventions strategies aimed at reducing V. vulnificus levels in oysters and therefore the associated risk of illness.--Publisher's description.
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  • Part 1 : General considerations -- Basic medical malpractice terminology -- The defense attorney -- The plaintiff's attorney -- The trial judge -- The medical expert -- Sequence of events in a medical malpractice lawsuit -- Informed consent -- The five most effective risk prevention strategies -- Revelation of adverse events and the conundrum of an apology -- Part 2 : Risk management in the ophthalmic subspecialties and related fields -- Anesthesia -- Cataract surgery -- Cornea : external disease and contact lenses -- Drugs -- Emergencies -- Glaucoma -- Neuroophthalmology -- Oncology -- Ophthalmic plastic surgery -- Pediatric ophthalmology -- Refractive corneal surgery -- Retina and vitreous -- Uveitis -- Part 3 : Personal and business considerations -- Physician and defendant : living and coping with a double life -- Medical malpractice insurance : selection of companies and policies.
  • Disaster risk management and risk impact: Risk concept, integral risk management and risk governance / W.J. Amman ; Risk based regulation / H. Seiler ; Emerging risk and risk management policies in selected OECD countries / P.-A. Schieb ; Vulnerability analysis, livelihoods and disasters / T. Cannon ; Crisis invention and risk reduction / D. Alexander -- Risk perception, aversion, risk levels: Risk aversion : a delicate issue in risk assessment / Th. Schneider ; Evaluation of risks due to natural hazards : a conceptual approach / Th. Schneider ; Challenges in defining acceptable risk levels / R. Bell, T. Glade & M. Danscheid ; Risk as perceived and evaluated by the general public / M.M. Zwick ; Understanding risk perception from natural hazards : examples from Germany / T. Plapp & U. Werner ; The cognitive representation of global risks : empirical studies / A.D. Eisler, H. Eisler & M. Yoshida ; Gender studies : social and psychological issues in disaster reduction / D. Mukhopadhyay -- Risk analysis, risk management and sustainability: Post-harvest management strategies, drought vulnerability and food security / C. Ifejika Speranza & U. Wiesmann ; CEDIM-risk map Germany : first results / C. Lechtenbörger ; Efficiency of protection measures / H. Weck-Hannemann -- Application of the marginal cost approach and cost-benefit analysis to measures for avalanche risk reduction : a case study from Davos, Switzerland / M. Bründl, M.C. McAlpin, U. Gruber & S. Fuchs ; TripelBudgetierung, sustainable integral risk management / H.-O. Schiegg & P. Hardegger ; Building vulnerability related to floods and debris flows-- case studies / D. Kraus, J. Hubl & D. Rickenmann ; Management of risks from large landslides : the problems of acceptable and residual risks / Ch. Bonnard & L. Vulliet ; Panarchy and sustainable risk prevention by management protection forests in mountain areas / L.K.A. Dorren & F. Berger ; Protective measures and risk management-- basics and examples of avalanche and torrential risks in Switzerland / H. Romang & S. Margreth ; The vulnerability of buildings affected by powder avalanches / M. Barbolini .. [et al.] ; Temporal variability of damage potential in settlements-- a contribution towards the long-term development of avalanche risk / S. Fuchs ... [et al.] -- Outlook.
  • "Smoking light and low tar brands do not reduce the public health's burden from smoking."
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    Risk and medical innovation : a historical perspective / Thomas Schlich -- To assess and to improve : practitioners' approaches to doubts linked with medical innovations 1720-1920 / Ulrich Tröhler -- Anaesthesia and the evaluation of surgical risk in mid-nineteenth century Britain / Ian Burney -- Redemption, danger and risk : the history of anti-bacterial chemotherapy and the transformation of tuberculin / Christoph Gradmann -- "As safe as milk or sugar water" : perceptions of the risks and benefits of the BCG vaccine in the 1920s and 1930s in France and Germany / Christian Bonah -- From danger to risk : the perception and regulation of X-rays in Switzerland, 1896-1970 / Monika Dommann -- The population as patient : Alice Stewart and the controversy over low-level radiation in the 1950s / Sarah Dry -- To treat or not to treat : drug research and the changing nature of essential hypertension / Carsten Timmermann -- Hormones at risk : cancer and the medical uses of industrially-produced sex steroids in Germany, 1930-1960 / Jean-Paul Gaudillière -- Risk assessment and medical authority in operative fracture care in the 1960 and 1970s / Thomas Schlich -- Assessing the risk and safety of the pill : maternal mortality and the pill / Lara Marks -- Addressing uncertainties : the conceptualization of brain death in Switzerland 1960-2000 / Silke Bellanger and Aline Steinbrecher -- Risk on trial : the interaction of innovation and risk in cancer clinical trials / Peter Keating and Alberto Cambrosio -- BioRisk : interleukin-2 from laboratory to market in the United States and Germany / Arthur Daemmrich -- The redemption of Thalidomide : standardizing the risk of birth defects / Stefan Timmermans and Valerie Leiter.
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    The Heart of the matter : for one family with a five-year-old with chronic disease, normal life is the greatest gift / by Kathryn Roethel -- Bus to nowhere : for Silicon Valley's homeless population, Hotel 22 is an endless ride / by Miranda Simon -- The Good death : "No One Dies Alone" is a volunteer program and a promise / by Ryan Mac -- The Clean room : why did so many IBM employees come down with cancer after working in Silicon Valley? / by Lily Bixler -- Shelter from the storm : in a time of budgetary crisis, abused women still need help / by Kristen Barta -- Punched in the gut : can a family ever recover from an eating disorder? / by Erin Beresini.
  • RNA 2001, ScienceDirect
  • RNA 2008, Springer Protocols
    The transcriptional landscape -- Working with RNA -- Synthesis of RNA by in vitro transcription -- Efficient poly(A)+ RNA selection using LNA oligo(T) capture -- Genome browsers -- Web-based tools for studying RNA structure and function -- Northern blotting analysis -- Rapid amplification of cDNA ends (RACE) -- Fractionation of mRNA based on the length of the poly(A) tail -- Analysis of mutations that influence pre-mRNA splicing -- S1 nuclease analysis of alternatively spliced mRNA -- Promises and challenges in developing RNAi as a research tool and therapy -- Inhibition of gene function in mammalian cells using short-hairpin RNA (shRNA) -- Validation of RNAi by real time PCR -- Profiling RNA polymerase II using the fast chromatin immunoprecipitation method -- The post-transcriptional operon -- RIP-chip analysis : RNA-binding protein immunoprecipitation-microarray (chip) profiling -- Isolation of RNP granules -- Electrophoretic mobility shift assay for characterizing RNA-protein interaction -- Polysome analysis and RNA purification from sucrose gradients -- Prediction of targets for microRNAs -- Outsourcing of experimental work.
  • Introduction /Michael Levitt --Modeling RNA Molecules /Neocles Leontis and Eric Westhof --Methods for Predicting RNA Secondary Structure /Kornelia Aigner, Fabian Dre€en and Gerhard Steger --Why Can't We Predict RNA Structure At Atomic Resolution? /Parin Sripakdeevong, Kyle Beauchamp and Rhiju Das --Template-Based and Template-Free Modeling of RNA 3D Structure: Inspirations from Protein Structure Modeling /Kristian Rother, Magdalena Rother, Michał Boniecki, Tomasz Puton and Konrad Tomala, et al. --The RNA Folding Problems: Different Levels of sRNA Structure Prediction /Fredrick Sijenyi, Pirro Saro, Zheng Ouyang, Kelly Damm-Ganamet and Marcus Wood, et al. --Computational Prediction and Modeling Aid in the Discovery of a Conformational Switch Controlling Replication and Translation in a Plus-Strand RNA Virus /Wojciech K. Kasprzak and Bruce A. Shapiro --Methods for Building and Refining 3D Models of RNA /Samuel C. Flores, Magdalena Jonikas, Christopher Bruns, Joy P. Ku and Jeanette Schmidt, et al. --Multiscale Modeling of RNA Structure and Dynamics /Feng Ding and Nikolay V. Dokholyan --Statistical Mechanical Modeling of RNA Folding: From Free Energy Landscape to Tertiary Structural Prediction /Song Cao and Shi-Jie Chen --Simulating Dynamics in RNA-Protein Complexes /John Eargle and Zaida Luthey-Schulten --Quantum Chemical Studies of Recurrent Interactions in RNA 3D Motifs /Jiří Šponer, Judit E. Šponer and Neocles B. Leontis --Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking /Neocles B. Leontis and Craig L. Zirbel --Ions in Molecular Dynamics Simulations of RNA Systems /Pascal Auffinger --Modeling RNA Folding Pathways and Intermediates Using Time-Resolved Hydroxyl Radical Footprinting Data /Joshua S. Martin, Paul Mitiguy and Alain Laederach --A Top-Down Approach to Determining Global RNA Structures in Solution Using NMR and Small-Angle X-ray Scattering Measurements /Yun-Xing Wang, Jinbu Wang and Xiaobing Zuo --RNA Structure Determination by Structural Probing and Mass Spectrometry: MS3D /A. E. Hawkins and D. Fabris.
  • RNA and cancer 2013, Springer
    Coupling Between Transcription and Alternative Splicing /Ignacio E. Schor, Luciana I. Gómez Acuña, Alberto R. Kornblihtt --Detection of Alternatively Spliced or Processed RNAs in Cancer Using Oligonucleotide Microarray /Marieta Gencheva ... [et al.] --Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing /Lulzim Shkreta ... [et al.] --Alternative Splicing of Tumor Suppressors and Oncogenes /Claudia Ghigna, Silvano Riva, Giuseppe Biamonti --MicroRNAs in Cancer /Jianzhong Jeff Xi --The Perinucleolar Compartment: RNA Metabolism and Cancer /John T. Norton, Sui Huang --Regulation of ARE-mRNA Stability by Cellular Signaling: Implications for Human Cancer /Christian Kroun Damgaard, Jens Lykke-Andersen --Alternative Pre-mRNA Splicing, Cell Death, and Cancer /Kong Ruirui ... [et al.] --Oligonucleotide Therapeutics in Cancer /Jing Wan, John A. Bauman, Maria Anna Graziewicz, Peter Sazani --Clinical Perspective on Chemo-Resistance and the Role of RNA Processing /Nancy L. Krett, Shuo Ma, Steven T. Rosen.
  • RNA editing 2007, ScienceDirect
  • RNA editing 2008, Springer
    Editing reactions from the perspective of RNA structure / Matthias Homann -- Editing of tRNA for structure and function / Juan D. Alfonzo -- RNA editing by adenosine deaminases that act on RNA (ADARs) / Michael F. Jantsch and Marie Öhman -- Insertion/deletion editing in Physarum polycephalum / Jonatha M. Gott and Amy C. Rhee -- RNA editing in plant mitochondria / Mizuki Takenaka ... [et al.] -- RNA editing in chloroplasts / Masahiro Sugiura -- Working together : the RNA editing machinery in Trypanosoma brucei / Jason Carnes and Kenneth Stuart -- RNA editing accessory factors : the example of mHel61p / H. Ulrich Göringer ... [et al.] -- The function of RNA editing in trypanosomes / Torsten Ochsenreiter and Stephen Hajduk -- Evolutionary aspects of RNA editing / Dave Speijer.
  • RNA exosome 2011, Springer
    "The diversity of RNAs inside living cells is amazing. We have known of the more "classic" RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of the book to introduce this fascinating protein complex and to give a timely and rich account of its many functions"--Provided by publisher.
  • RNA helicases. 1st ed. 2012, ScienceDirect
    This volume of Methods in Enzymology aims to provide a reference for the diverse, powerful tools used to analyze RNA helicases. The contributions in this volume cover the broad scope of methods in the research on these enzymes. Several chapters describe quantitative biophysical and biochemical approaches to study molecular mechanisms and conformational changes of RNA helicases. Further chapters cover structural analysis, examination of co-factor effects on several representative examples, and the analysis of cellular functions of select enzymes. Two chapters outline approaches to the analysis of inhibitors that target RNA helicases. This volume of Methods in Enzymology aims to provide a reference for the diverse, powerful tools used to analyze RNA helicases The contributions in this volume cover the broad scope of methods in the research on these enzymes.
  • The RNA infrastructure : an introduction to ncRNA networks / Lesley J. Collins -- RNA interactions / Manja Marz and Peter F. Stadler -- Plant RNA silencing in viral defence / Vitantonio Pantaleo -- Micrornas as post-transcriptional machines and their interplay with cellular networks / Sarath Chandra Janga and Swathi Vallabhaneni -- Spatiotemporal aspects of microRNA-mediated gene regulation / Joris Pothof and Dik C. van Gent -- Spliceosomal RNA infrastructure : the network of splicing components and their regulation by miRNAs / Lesley J. Collins -- Construction, structure, and dynamics of post-transcriptional regulatory network directed by RNA binding proteins / Sarath Chandra Janga and Nitish Mittal -- Safe keeping the message : mRNP complexes tweaking after transcription / Said Hafidh, Věra Čapková, and David Honys -- Unexpected functions of tRNA and tRNA processing enzymes / Rebecca L. Hurto -- Programmed DNA elimination in tetrahymena : a small RNA mediated genome surveillance mechanism / Kensuke Kataoka and Kazufumi Mochizuki -- Long noncoding RNA and epigenomics / Chandrasekhar Kanduri -- Promoter associated long noncoding RNAs repress transcription through a RNA binding protein TLS / Riki Kurokawa -- RNA networks in prokaryotes I :CRISPRs and riboswitches / Patrick J. Biggs and Lesley J. Collins -- RNA networks in prokaryotes II : tRNA processing and small RNAs / Lesley J. Collins and Patrick J. Biggs -- Localization of the bacterial RNA infrastructure / Kenneth C. Keiler -- Small RNA discovery and characterisation in eukaryotes using high throughput approaches / Helio Pais ... [et al.] -- How old are RNA networks? / Toni Daly, X. Sylvia Chen, and David Penny.
  • RNA interference 2005, ScienceDirect
  • RNA interference 2008, Springer
    RNA interference in mammalian cell systems / Patrick J. Paddison -- RNAi pathway in C. elegans: the argonautes and collaborators / Marie-Eve L. Boisvert and Martin J. Simard -- Genetics and biochemistry of RNAi in drosophila / Harsh H. Kavi ... [et al.] -- Role of dicer in posttranscriptional RNA silencing / Lukasz Jaskiewicz and Witold Filipowicz -- The mechanism of RNase III action: how dicer dices / Xinhua Ji -- MicroRNA metabolism in plants / Xuemei Chen -- Structure-function relationships among RNA-dependent RNA polymerases / Kenneth K.-S. Ng, Jamie J. Arnold, and Craig E. Cameron -- RNAi-mediated chromatin silencing in fission yeast / Sharon A. White and Robin C. Allshire -- A role for RNAi in heterochromatin formation in drosophila / Nicole C. Riddle and Sarah C.R. Elgin -- RNA mediated transcriptional gene silencing in human cells / Kevin V. Morris -- RNA silencing in mammalian oocytes and early embryos / Petr Svoboda -- Identifying human microRNAs / Isaac Bentwich.
  • The Nobel Prize winning discovery that small interfering RNA can be utilised to control cellular gene expression has propelled the field of RNA interference (RNAi) to the forefront of biomedical science as a potential molecular medicine set to revolutionalise disease treatment. Harnessing the molecular mechanisms of RNAi and development of delivery technologies is crucial for its transformation into a therapeutic modality, this dependency is the focus of "RNA Interference from Biology to Therapeutics" that gives a comprehensive overview of RNAi biology and state-of-the-art delivery methods relevant to clinical translation of RNAi therapeutics. Key players and shapers in the fields of RNAi and delivery science have been assembled in a single volume to produce a truly unique interdisciplinary text, making it a "must-read" for both students and experts in, and at the interface of, RNAi, pharmaceutical science and medicine. An attractive feature is the "future perspectives" section within each chapter that allows global leaders the opportunity to express their views on the direction the field is moving. Topics covered in the book include miRNA biology and therapeutic exploitation, exosome delivery and clinical translation."RNA Interference from Biology to Therapeutics" is an up-to-the-minute, highly informative and invaluable text for those actively involved or interested in this fascinating and high-impact field.
  • RNA interference technology 2005, MyiLibrary
    Chemical modifications to achieve increased stability and sensitive detection of siRNA -- RNA interference in postimplantation mouse embryos -- In ovo RNAi opens new possibilities for functional genomics in vertebrates -- Sect. 4. Gene silencing in model organisms. Practical applications of RNAi in C. elegans -- Inducible RNAi as a forward genetic tool in Trypanosoma brucei -- RNA-mediated gene silencing in fission yeast -- RNA silencing in filamentous fungi: Mucor ciccinelloides as a model organism -- RNAi and gene silencing phenomena mediated by viral suppressors in plants --Sect. 1. Basic RNAi, siRNA, microRNAs and gene-silencing mechanisms. RNAi beginnings. Overview of the pathway in C. elegans -- Dicer in RNAi: its roles in vivo and utility in vitro -- Genes required for RNA interference -- MicroRNAs: a small contribution from worms -- miRNAs in the brain and the application of RNAi to neurons -- Sect. 2. Design, synthesis of siRNAs. Degign and synthesis of small interfering RNA (siRNA) -- Automated design and high throughput chemical synthesis of siRNA -- Rational design of siRNAs with the Sfold software -- Enzymatic production of small interfering RNAs -- Sect. 3. Vector development and in vivo, in vitro and in ovo delivery methods. Six methods of inducing RNAi in mammalian cells -- Viral delivery of shRNA -- siRNA delivery by lentiviral vectors: design and applications -- Liposomal delivery of siRNAs in mice --Sect. 5. Drug target validation. Delivering siRNA in vivo for functional genomics and novel therapeutics -- The role of RNA interference in drug target validation: application to Hepatitis C -- RNAi in the drug discovery process -- RNA interference technology in the discovery and validation of druggable targets -- Sect. 6. Therapeutic and drug development. RNAi-mediated silencing of viral gene expression and replication -- RNAi in drug development: practical considerations -- RNA interference studies in liver failure -- RNAi applications in living animal systems -- Sect. 7. High-throughput genome-wide RNAi analysis. High-throughput RNAi by soaking in Caenorhabtis elegans -- Tools for integrative genomics: genome-wide RNAi and expression profiling in Drosophila -- Microarray analysis and RNA silencing to determine genes functionally important in mesothelioma -- High-throughput RNA interference -- Generation of highly specific vector-based shRNAi libraries directed against the entire human genome.
  • 1. RNA polymerases and transcription factors of trypanosomes / Arthur Günzl -- 2. SL RNA biogenesis in kinetoplastids: a long and winding road / Nancy R. Sturm, Jesse R. Zamudio, and David A. Campbell -- 3. Pre-mRNA splicing in trypanosoma brucei: factors, mechanisms, and regulation / Christian Preusser, Nicolas Jaé, Arthur Günzl, and Albrecht Bindereif -- 4. mRNA turnover in trypanosomes / Christine Clayton -- 5. tRNA biogenesis and processing / Jessica L. Spears, Mary Anne T. Rubio, Paul J. Sample, and Juan D. Alfonzo -- 6. rRNA biogensis in trypanosomes / Shulamit Michaeli -- 7. RNA editing in African trypanosomes: a U-ser's G-U-ide / H. Ulrich Göringer -- 8. The RNA interference pathway in trypanosoma brucei / Elisabetta Ullu, Nikolay G. Kolev, Rebecca L. Barnes, and Christian Tschudi -- 9. Translation in trypanosomatids -- 10. Mitochondrial translation in trypanosomatids / Dmitri A. Maslov and Rajendra K. Agrawal -- 11. RNA-Seq analysis of the transcriptome of trypanosoma brucei / Jan Mani, Kapila Gunasekera, and Isabel Roditi.
  • RNA methodologies. 4th ed. 2010, ScienceDirect
    RNA and the cellular biochemistry revisited -- RNA isolation strategies -- The truth about tissues -- Going green : RNA and the molecular biology of plants -- Isolation of polyadenylated RNA -- Quality control for RNA preparations -- Resilient ribonucleases -- Stringency : conditions that influence nucleic acid structure -- Electrophoresis of RNA -- Photodocumentation and image analysis -- Northern analysis -- Nucleic acid probe technology -- Practical nucleic acid hybridization -- Principles of detection -- Quantifications of specific mRNAs by nuclease protection -- Analysis of nuclear RNA -- cDNA synthesis -- RT-PCR : a science and an art form -- Quantitative PCR techniques -- Functional genomics and transcript profiling -- High-throughput analysis of gene expression -- Non-array methods for global analysis of gene expression -- RNAi : take a RISC-role the dicer -- Genomes, transcriptomes, proteomes, and bioinformatics -- An RNA paradigm.
  • RNA modification 2007, ScienceDirect
  • Section 1. Introduction : principles and fundamentals of RNA nanotechnology -- section 2. RNA folding, structure, and motifs in RNA nanoparticle assembly -- section 3. RNA computation and structure prediction for RNA nanoparticle construction -- section 4. RNA chemistry for nanoparticle synthesis, conjugation, and labeling -- section 5. Single-molecule and biophysical techniques in RNA nanostructure analysis -- section 6. Methods for the assembly of RNA nanoparticles -- section 7. RNA nanoparticles for therapy of cancer, viral infections, and genetic diseases -- section 8. RNA nanotechnology for diagnostic applications -- section 9. Application of RNA aptamers in RNA nanotechnology and therapeutics -- section 10. Application of miRNAs in RNA nanotechnology and therapeutics -- section 11. Application of siRNAs in RNA nanotechnology and therapeutics.
  • pt. D ScienceDirect
  • RNA silencing 2005, Springer Protocols
    Detection of microRNAs and assays to monitor microRNA activities in vivo and in vitro / Marianthi Kiriakidou ... [et al.] -- High-throughput analysis of microRNA gene expression using sensitive probes / Mouldy Sioud and Øystein Røsok -- Modification of human U1 snRNA for inhibition of gene expression at the level of pre-mRNA / Peng Liu ... [et al.].Identification of components of RNAi pathways using the tandem affinity purification method / Mikiko C. Siomi and Haruhiko Siomi -- Separation of Drosophila RNA silencing complexes by native gel electrophoresis / John W. Pham and Erik J. Sontheimer -- Preparation and analysis of drosha / Yoontae Lee and V. Narry Kim -- RNA interference in Caenorhabditis elegans / Nathaniel R. Dudley and Bob Goldstein -- Down-regulating gene expression by RNA interference in Trypanosoma brucei / Christine E. Clayton ... [et al.] -- Analysis of double-stranded RNA and small RNAs involved in RNA-mediated transcriptional gene silencing / M. Florian Mette ... [et al.] -- Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs / Mouldy Sioud and Sébastien Wälchli -- Silencing gene expression with dicer-generated siRNA pools / Jason W. Myers and James E. Ferrell Jr. --Inhibition of gene expression in vivo using multiplex siRNA / Sung-Suk Chae and Timothy Hla -- Gene silencing by a DNA vector based RNAi technology / Guangchao Sui and Yang Shi -- Plasmid-based RNA interference: construction of small-hairpin RNA expression vectors / Scott Q. Harper and Beverly L. Davidson -- SiRNA delivery in vivo / Mouldy Sioud -- Peptide-based strategy for siRNA delivery into mammalian cells / Federica Simeoni ... [et al.] -- Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells / Mingjie Li and John J. Rossi -- Exon-specific RNA interference: a tool to determine the functional relevance of proteins encoded by alternatively spliced mRNAs / Alicia M. Celotto, Joo-Won Lee, and Brenton R. Graveley -- Immunoprecipitation of microRNPs and directional cloning of microRNAs / Elisavet Maniataki, Maria Dels Angels De Planell Saguer, and Zissimos Mourelatos --
  • The key features of RNA silencing / Kuniaki Saito ... [et al.] -- Selected strategies for the delivery of siRNA in vitro and in vivo / Sandra D. Laufer ... [et al.] -- RNAi suppression and its application / Xiaoping Yi, Rui Lu -- Strategies to prevent siRNA-triggered cellular toxicity / Matthias Bauer -- RNAi in malignant brain tumors: relevance to molecular and translational research / Mitsutoshi Nakada ... [et al.] -- Silencing Huntington's disease gene with RNAi / Yu Zhang, Robert M. Friedlander -- Application of Dicer-substrate siRNA in pain research / Philippe Sarret ... [et al.] -- RNAi treatment of HIV-1 infection / Karin J. von Eije, Ben Berkhout -- Application of RNA interference to treat conditions associated with dysregulation of transient receptor potential vanilloid 1 channel / Vickram Ramkumar ... [et al.] -- Harnessing RNAi-based functional genomics to unravel the molecular complexity underlying skin pigment variation / Hsiang Ho ... [et al.] --mRNA structure and its effects on posttranscriptional gene silencing / Stephen I. Rudnick, Veenu Aishwarya, Alan M. Gewirtz -- Antisense RNA-mediated regulation of the p53 tumor suppressor / Marianne Farnebo, Klas G. Wiman -- Antisense oligonucleotides: insights from preclinical studies and clinical trials / Doreen Kunze, Kai Kraemer, Susanne Fuessel -- What can the new hammerhead ribozyme structures teach us about design? / William G. Scott -- microRNA biogenesis and its impact on RNA interference / Stefanie Grund, Sven Diederichs -- MicroRNAs in epithelial antimicrobial immunity / Jun Liu ... [et al.] -- Emerging roles of long noncoding RNAs in gene expression and intracellular organization / Tetsuro Hirose -- Noncoding RNAs as therapeutic targets / Maciej Szymański, Jan Barciszewski -- Noncoding RNAs at H19/IGF2 locus: role in imprinting, gene expression, and associated pathologies / Nahalie Berteaux, Nathalie Spruyt, Eric Adriaenssens.
  • RNA towards medicine 2006, Springer
  • RNA turnover in eukaryotes 2008, ScienceDirect
  • RNA turnover in eukaryotes 2008, ScienceDirect
  • RNA world. 3rd ed. SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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  • 1. Isolation of a sequence-specific RNA binding protein, polypyrimidine tract binding protein using RNA affinity chromatography / Shalini Sharma -- 2. An affinity oligonucleotide displacement strategy to purify ribonucleoprotein complexes applied to human telomerase /Isabel Kurth, Gaël Cristofari, Joachim Lingner -- 3. RNA affinity tags for the rapid purification and investigation of RNAs and RNA-protein complexes / Scott C. Walker ... [et al.] -- 4. Assembly and glycerol gradient isolation of yeast spliceosomes containing transcribed or synthetic U6 SnRNA / Ken Dery, Shyue-Lee Yean, Ren-Jang Lin -- 5. Purification of ribonucleoproteins using peptide-elutable antibodies and other affinity techniques / Scott Stevens -- 6. CLIP: cross-linking and immunoprecipitation of in vivo RNA targets of RNA binding proteins / Kirk B Jensen, Robert B. Darnell -- 7. Quantitative analysis of protein-RNA interactions by gel mobility shift / Sean P. Ryder, Michael I. Recht, James R. Williamson -- 8. Monitoring assembly of ribonucleoprotein complexes by isothermal titration calorimetry / Michael I. Recht, Sean P. Ryder, James R. Williamson -- 9. Characterization of RNA-protein interactions by phosphorothioate footprinting and its applications to the ribosome / A. Ozlem Tastan Bishop, ... [et al.] -- 10. In vivo analysis of ribonucleoprotein complexes using nucleotide analog interference mapping / Lara Weinstein Szewczak -- 11. T7 RNA polymerase mediated incorporation of 8-N3AMP into RNA for studying protein-RNA interactions / Rajesh Gaur -- 12. A simple crosslinking method, CLAMP, to map the sites of RNA contacting domains within a protein / Hiren Banerjee, Ravinder Singh -- 13. Proteins specifically modified with a chemical nuclease as probes of RNA-protein interaction / Oliver A. Ken, Andrew M. MacMillan -- 14. RNA-protein crosslink mapping using TEV protease / Ian A. Turner, ... [et al.] -- 15 Structural analysis of protein-RNA interactions with mass spectrometry / Mamuka Kvaratskhelia, Stuart F.J. Le Grice -- 16. Analysing RNA-protein cross-linking sites in unlabeled ribonucleoprotein complexes by mass spectrometry / Henning Urlaub, Eva Kühn-Hölsken, Reinhard Lührmann --17. In vitro selection of random RNA fragments to identify protein binding sites within large RNAs / Ulrich Stelzl, Knud H. Nierhaus -- 18. Immunoprecipitation analysis to study RNA-protein interactions in xenopus oocytes / Naoto Mabuchi, Kaoru Masuyama, Mutsuhito Ohno -- 19. Mapping the regions of RNase P catalytic RNA that are potentially in close contact with its protein cofactor / Phong Trang, Fenyong Liu -- 20. Quantification of microRNAs, splicing isoforms, and homologous mRNAs with the invader assay / Peggy S. Eis, Mariano Garcia-Blanco -- 21. Analysis of RNA structure and RNA-protein interactions in mammalian cells by use of terminal transferase-dependent PCR / Hsiu-Hua Chen, Jeanne LeBon, Arthur D. Riggs -- 22. Duplex unwinding and RNP remodeling with RNA helicases / Eckhard Jankowsky, Margaret E. Fairman -- 23. Preparation of efficient splicing extracts from whole cells, nuclei, and cytoplasmic fractions / Naoyuki Kataoka, Gideon Dreyfuss -- 24. Designing and utilization of siRNAs targeting RNA-binding proteins / Dong-Ho Kim, Mark Behlke, John J. Rossi -- 25. The use of saccharomyces cerevisiae proteomic libraries to identify RNA-modifying proteins / Jane E. Jackman, Eric M. Phizicky.
  • RNAi 2008, Springer Protocols
  • RNAi technology 2011, CRCnetBASE
    "RNA interference (RNAi) is a system within living cells that helps to control active genes and their activity level. Two types of small RNA molecules--microRNA (miRNA) and small interfering RNA (siRNA)--are central to RNA interference. The discovery of RNAi was preceded first by observations of transcriptional inhibition by antisense RNA expressed in transgenic plants and more directly by reports of unexpected outcomes in experiments performed by plant scientists in the U.S. and The Netherlands in the early 1990s. RNAi technology are used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. This book reviews the selective and robust effect of RNAi on gene expression which makes it a valuable research tool, both in cell culture and in living organisms because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. This book will introduce new technology in the study of RNA interference in microorganisms, plants and animals."--Provided by publisher.
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    Cell injury, cell death, and adaptations -- Acute and chronic inflammation -- Tissue repair : regeneration, healing, and fibrosis -- Hemodynamic disorders, thrombosis, and shock -- Diseases of the immune system -- Neoplasia / Thomas P. Stricker, Vinay Kumar -- Environmental and nutritional diseases -- General pathology of infectious diseases -- The blood vessels -- The heart / Frederick J. Schoen, Richard N. Mitchell -- The hematopoietic and lymphoid systems / Jon C. Aster -- The lung / Anirban Maitra, Vinay Kumar -- The kidney and its collecting system / Charles E. Alpers , Agnes B. Fogo -- The oral cavity and gastrointestinal tract -- The liver, gallbladder, and biliary tract -- The pancreas -- The male genital system -- The female genital system / Anthony Montag, Vinay Kumar -- The endocrine system / Anirban Maitra -- The musculoskeletal system -- The skin / Alexander J.F. Lazar -- The nervous system / Matthew P. Frosch.
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  • Vital signs and patient monitoring techniques -- Respiratory procedures -- Cardiac procedures -- Vascular techniques and volume support -- Anesthetic and analgesic techniques -- Soft tissue procedures -- Gastrointestinal procedures -- Musculoskeletal procedures -- Genitourinary, obstetric, and gynecologic procedures -- Neurologic procedures -- Ophtalmologic, otolaryngologic, and dental procedures -- Special procedures.
  • Laparoscopic and robotic instrumentation for urologic reconstructive surgery in adults -- Instrumentation during pediatric robotic anastomoses and reconstruction -- Instrumentation during pediatric laparoscopic robotic anastomoses and reconstruction -- Adult laparoscopic partial nephrectomy for renal cell carcinoma -- Adult robotic-assisted partial nephrectomy for renal cell carcinoma -- Pediatric laparoscopic and robotic upper pole nephrectomy for nonfunctioning moieties -- Adult laparoscopic and robotic-assisted pyeloplasty for ureteropelvic junction obstruction -- Pediatric laparoscopic (infant, pre-pubertal, and teenager) pyeloplasty for ureteropelvic junction obstruction -- Pediatric robotic (infant, pre-pubertal, and teenager) pyeloplasty for ureteropelvic junction obstruction -- Laparoscopic ureteroureterostomy and correction of ureteral defects -- Robotic ureteroureterostomy and correction of ureteral defects -- Robotic radical cystectomy and use of intestinal segments for reconstruction in the adult patient -- Laparoscopic bladder augmentation and creation of continent-catheterizable stomas in the pediatric patient -- Laparoscopic ureteral reimplant surgery to correct reflux disease -- Robotic ureteral reimplant surgery to correct reflux disease -- Laparoscopoic and robotic orchiopexy for the impalpable undescended testicle -- Laparoscopic anastomoses and bladder neck reconstruction following radical prostatectomy -- Robotic anastomoses and bladder neck reconstruction following radical prostatectomy -- The role of NOTES and LESS in minimally invasive reconstructive urological surgery -- Laparoscopy and robotics in stress urinary incontinence and pelvic reconstructive surgery.
  • Robotic cardiac surgery 2014, Springer
    Robotic Cardiac Surgery is a comprehensive guide to robotic/totally endoscopic cardiac surgery. The book is intended to provide in-depth information regarding the history of robotic surgical systems, their components and principles. It emphasizes patient selection, perioperative management, anesthesia considerations and management, operative techniques and management, postoperative care and results. Extensive, detailed photographs and illustrations of different kinds of robotic surgery are also included. It provides cardiac surgeons, cardiac anesthesiologists, and perfusionists with a comprehensive review of current robotic cardiac surgeries and related knowledge.
  • Robotic Donor Nephrectomy - A Practical Guide is a user friendly manual aimed to give both novice and mature urologists a clear and comprehensive description of robot-assisted laparoscopic donor nephrectomy through a step-by-step approach. Novel techniques such as the Laparo-Endoscopic Single-Site (LESS) surgery are examined and the editors also look at the well established multi-ports techniques using the da Vinci Surgical system. Robotic Donor Nephrectomy - A Practical Guide will help young urologists gain better understanding of the techniques of robotic-assisted surgery, and support older urologists in 'crossing the border' towards laparoscopic surgery, particularly for delicate procedures such as the donor nephrectomy.
  • Robotic renal surgery 2013, Springer
    Part I: Robotic Technology and Instrumentation -- Robotic Technology and Ancillary Instruments in Renal Surgery -- Preoperative Preparation and Positioning for Robotic Renal Surgery -- Part II: Nephrectomy -- Robotic Simple and Radical Nephrectomy -- Robotic Donor Nephrectomy: Hand-Assisted Technique -- Robotic Nephrectomy for Complex Tumors -- Part III: Partial Nephrectomy -- Robotic Partial Nephrectomy: Basic Principles and Techniques -- Robot-Assisted Partial Nephrectomy: Complex Tumors and Evolving Techniques -- Near-Infrared Fluorescence Imaging in Robotic Partial Nephrectomy -- Part IV: Upper Urinary Tract Surgery -- Robotic Pyeloplasty -- Robotic Nephroureterectomy -- Robotic Ureteral Resection and Reconstruction for Urothelial Tumors and Benign Disease -- Part V: Pediatric Robotic Renal and Ureteral Surgery -- Upper Tract Obstruction -- Vesicoureteral Reflux and Ureteral Reimplantation -- Part VI: Advanced and Evolving Robotic Renal Techniques -- Retroperitoneal Robotic Kidney Surgery -- Single-Incision Robotic Renal and Ureteral Surgery.
  • Robotic surgery 2014, Springer
    1. Overview of robotic surgery -- 2. The de Vinci Surgical® systesm -- 3. Development of robotic systems -- 4. Robotic surgery in urology -- 5. Robotic gastrectomy for gastric cancer -- 6. Esophageal cancer surgery: robotic esophagectomy - 7. Lateral pelvic node dissection for advanced rectal cancer: current debates and use of the robotic approach -- 8. Cardiac surgery: overview -- 9. Robotically assisted totally endoscopic coronary artery bypass grafting -- 10. Robotic surgery for mitral valve disease -- 11. Robotic surgery in general thoracic surgery -- 12. Robot-assisted thyroidectomy.
  • Robotic Surgery of the Bladder is a dedicated resource to understanding and mastering the concepts and practical aspects of robotic bladder surgery. The volume provides an introduction to urologists interested in initiating robotic radical cystectomy by providing them background, concepts, steps, and tools and tricks to introduce robotic radical cystectomy into their clinical practice, all in a safe, stepwise, and organized manner. For the more experienced robotic surgeon, the text serves as a resource for more advanced applications and techniques. The volume is also accompanied by many still images and a DVD of video clips. Written by experts in the field, Robotic Surgery of the Bladder is a comprehensive resource that maintains the time-tested oncologic principles of bladder cancer surgery, while introducing the advantages that exist with robotic-assisted approaches.
  • Pt. 1. Introduction to robotic surgery -- Pt. 2. Robotic surgery of the prostate -- Pt. 3. Kidney and adrenals -- Pt. 4. Bladder cancer -- Pt. 5. Pediatric urology -- Pt. 6. Robotic microsurgery -- Pt. 7. Allied health -- Pt. 8. Executive.
  • Robotic urology. 2nd ed. 2013, Springer
    Part I: Kidneys -- Surgical Anatomy of Kidneys and Adrenals -- Robotic Kidney Surgery -- Partial Resection of the Kidney for Renal Cancer -- Robotic Nephroureterectomy -- Robotic Pyeloplasty -- Part II: Adrenals -- Robotic Adrenal Surgery -- Part III: Pelvis -- Surgical Anatomy of Pelvic Lymph Nodes -- Robotic-Assisted Pelvic Lymph Node Dissection -- Pelvic Lymphadenectomy for Localised Prostate Cancer and Robot-Assisted Radical Prostatectomy -- Part IV: Bladder -- Surgical Anatomy of the Bladder -- Robotic-Assisted Radical Cystectomy for Bladder Cancer in the Female -- Male Robot-Assisted Radical Cystectomy -- Robotic-Assisted Intracorporeal Urinary Diversion -- Technique of Extracorporeal Urinary Diversion -- Robot-Assisted Laparoscopic Ureteral Reimplantation -- Part V: Prostate -- Surgical Anatomy of the Prostate for Radical Prostatectomy -- Anatomical Aspects of the Neurovascular Bundle in Prostate Surgery -- Part VI: Benign Disease -- Robotic Adenomectomy -- Part VII: Radical Prostatectomy -- Trans- and Extraperitoneal Approach for Robotic-Assisted Radical Prostatectomy -- Radical Prostatectomy: Anterior Approach -- Robotic Prostatectomy: The Posterior Approach -- Bladder Neck Dissection During Robotic-Assisted Laparoscopic Radical Prostatectomy -- Techniques of Nerve Sparing in Robot-Assisted Radical Prostatectomy -- Antegrade Robot-Assisted Radical Prostatectomy: Factors Impacting Potency Preservation -- Allogenic Nerve Interposition During Non-Nerve-Sparing Robot-Assisted Radical Prostatectomy -- The Apical Dissection -- Posterior Reconstruction of the Rhabdosphincter -- The Urethrovesical Anastomosis -- Robotic-Assisted Laparoscopic Radical Salvage Prostatectomy -- Outcome Measures After Robot-Assisted Radical Prostatectomy -- Urinary Incontinence After Robotic-Assisted Laparoscopic Radical Prostatectomy -- Part VIII: Reconstructive Urology -- Paediatric Pelvic Exenteration -- Robot-Assisted Laparoscopy for Genital Organ Prolapse -- Robot-Assisted Laparoscopic Repair of Supratrigonal Vesicovaginal Fistulae with Peritoneal Flap Inlay -- Robotic Surgical Training: Imparting Necessary Skills to Future Urologic Surgeons.
  • Robotics in General Surgery provides a comprehensive review of the current applications of the robotic platform in all the general surgery subspecialties. Additionally, for each subspecialty it serves as a procedure-oriented instruction manual in terms of technical details of procedures, including fundamentals of robot positioning and trocar placement, step-by-step description of procedures, comprehensive discussions of advantages, limitations, indications, and relative contraindications of using the robotic approach. The text also discusses the challenges and steps to overcoming these challenges in transitioning from a minimally invasive to a robotic practice/surgeon. Lastly, this volume addresses emerging technology in robotics and the impact that the robotics platform will have on not only practice of surgery, but also in the education of surgeons at all levels. Written by experts in the field of robotic surgery, Robotics in General Surgery is a valuable resource for general surgeons of all levels including residents, fellows and surgeons already in practice.
  • The History of Robotic Surgery -- Robotic Instrumentation and Operating Room Setup -- Port Placement in Robotic Urologic Surgery -- Achieving Efficiency in the Operating Room: Step by Step -- Laparoscopy vs. Robotics: Ergonomics -- Does It Matter? -- Anesthetic Considerations for Robotic Urologic Surgery -- The Development of a Robotic Urology Program in the UK -- Robotic Urologic Surgery: How to Make an Effective Robotic Program -- Witnessing the Transition of Open to Robotic Surgery -- Patient-Side Surgeons: The Unsung Heroes of Robotic Surgery -- Training in Robotic Urologic Surgery -- Animal Laboratory Training: Current Status and How Essential Is It? -- Training of Operating Room Technician and Nurses in Robotic Surgery -- Impact of Virtual Reality Simulators in Training of Robotic Surgery -- Training, Credentialing, and Hospital Privileging for Robotic Urological Surgery -- Research in Urologic Oncology in an Era of Minimally Invasive Surgery -- Databases and Data Management for Robotic Surgery -- The Role of Scientific Journals in Disseminating New Technology -- Predicting Robotic Utilization in Urologic Disease: An Epidemiology-Based Model -- Development of the Vattikuti Institute Prostatectomy: Historical Perspective and Technical Nuances -- Transferring Knowledge of Anatomical Dissection from the Laboratory to the Patient: An Australian Perspective -- Robot-Assisted Radical Prostatectomy: A Prostate Surgeon's Perspective -- Cautery-Free Technique of Robot-Assisted Radical Prostatectomy: Impact on Nerve Preservation and Long-Term Outcome on Recovery of Sexual Function -- Current Concepts in Cavernosal Neural Anatomy and Imaging and Their Implications for Nerve-Sparing Radical Prostatectomy -- Robot-Assisted Radical Prostatectomy for Large Glands and Median Lobe -- Extraperitoneal Robot-Assisted Radical Prostatectomy: Simulating the Gold Standard -- The Retrograde Extraperitoneal Approach: Robotic Retrograde Extraperitoneal Laparoscopic Prostatectomy (RRELP). Technical Modifications for Robotic Prostatectomy -- Robotic Radical Prostatectomy: Cancer Control and Implications of Margin Positivity -- Techniques to Improve Urinary Continence Following Robot-Assisted Radical Prostatectomy -- Penile Rehabilitation After Robotic Radical Prostatectomy: The Best Strategy -- Laparoscopy or Robotic Radical Prostatectomy: Pros and Cons -- Complications of Robotic Prostatectomy -- Robotic Urologic Surgery: Robotic-Assisted Adrenalectomy -- Robot-Assisted Laparoscopic Radical Nephrectomy and Nephroureterectomy -- Robot-Assisted Partial Nephrectomy -- Robotic Urologic Surgery: Robot-Assisted Partial Nephrectomy -- Robotic Donor Nephrectomy: Technique and Outcomes -- An European Perspective -- Robot-Assisted Laparoscopic Pyeloplasty -- Robotic Surgery for Urolithiasis -- Ureteral Reconstruction Utilizing Robotic-Assisted Techniques -- Robotic or Laparoscopic Renal Surgery: Pros and Cons -- Robot-Assisted Radical Cystectomy in Male: Technique of Spaces -- Robotic-Assisted Laparoscopic Anterior Pelvic Exenteration for Bladder Cancer in the Female -- Robotic-Assisted Laparoscopic Extended Pelvic Lymph Node Dissection for Bladder Cancer -- Robot-Assisted Intracorporeal Ileal Conduit -- Robotic Urinary Diversion: Technique, Current Status, and Outcomes -- Robotic Bladder Surgery Complications: Prevention and Management -- Robotic Surgery for Ureteral Anomalies in Children -- Robotic Surgery of the Kidney in Children -- Robotic Bladder Surgery in Children -- Robotic Surgery in Urogynecology -- Robotic Repair of Vesico-vaginal Fistula -- Robotic Surgery in Male Infertility (Robotic-Assisted Microsurgery) -- Treater to Target: Experiences of a Prostate Cancer Participant -- My Prostate Cancer -- Telementoring and Telesurgery in Urology -- Robotic Systems: Past, Present, and Future.
  • Biomechanics of fixation and fractures /Allan F. Tencer --Classification of fractures /Douglas R. Dirschl and Lisa K. Cannada-- Management of the multiply injured patient /Hans-Christoph Pape and Peter Giannoudis --The epidemiology of fractures. pt. 1. Overview of epidemiology /Charles M. Court-Brown and Benjamin C. Caesar --pt. 2. Experience in the United States /Kenneth J. Koval and Michael Cooley --Nonoperative fracture treatment /John F. Connolly --Principles of internal fixation /Christian Krettek and Thomas Gösling --Principles of external fixation /J. Tracy Watson --Bone and joint healing /Joseph A. Buckwalter, Thomas A. Einhorn and J.L. Marsh --Bone grafting and enhancement of fracture repair /Sanjeev Kakar, Eleftherios Tsiridis, and Thomas A. Einhorn --Outcome studies in trauma /Mohit Bhandari --Imaging considerations in orthopaedic trauma /Andrew H. Schmidt and Kerry M. Kallas --Initial management of open fractures /Steven A. Olson and Mark C. Willis --Acute compartment syndrome /Margaret M. McQueen --Penetrating trauma /Edward A. Perez --War wounds, limb salvage, and traumatic amputations /Paul J. Dougherty --Bone and soft tissue reconstruction /Lior Heller and L. Scott Levin --Systemic complications /David C. Templeman and William A. Marinelli --Local complications /Kirti D. Moholkar and Bruce H. Ziran --Osteoporotic fractures /Magnus K. Karlsson, Karl Obrant and Per Olof Josefsson --Pathologic fractures /Kristy L. Weber --Stress fractures /David C. Teague --Periprosthetic fractures. pt. 1. Periprosthetic fractures of the elbow and shoulder /Robert H. Cofield ... [et al.] --pt. 2. Periprosthetic fractures about total hip and total knee replacements /Jay D. Mabrey --Computer-aided orthopaedic surgery in skeletal trauma /Meir Liebergall, Rami Mosheiff, and Leo Joskowicz --Fractures and dislocations of the hand /Mark H. Henry --Fractures and dislocations of the carpus /Christian Gaebler --Fractures of the distal radius and ulna /David S. Ruch --Fractures of the shafts of the radius and ulna /Ralph Hertel and Dominique A. Rothenfluh --Fractures and dislocations of the elbow /David Ring --Fractures of the distal humerus /C. Michael Robinson --Fractures of the shaft of the humerus /Michael D. McKee --Fractures of the proximal humerus /Jon J. P. Warner, John G. Costouros and Christian Gerber --Fractures of the clavicle /Mark D. Lazarus and Carl Seon --Fractures of the scapula /Kenneth P. Butters --Subluxations and dislocations about the glenohumeral joint /Young W. Kwon and Joseph D. Zuckerman --Acromioclavicular joint injuries /Leesa M. Galatz and Gerald R. Williams, Jr. --Injuries to the sternoclavicular joint /Gregory J. Gilot, Michael A. Wirth and Charles A. Rockwood, Jr. --Principles of spine trauma care /Sohail K. Mirza, Carlo Bellabarba and Jens R. Chapman --Injuries of the craniocervical junction /Carlo Bellabarba, Sohail D. Mirza and Jens R. Chapman --Fractures and dislocations of the lower cervical spine /Christopher M. Bono --Fractures and dislocations of the thoracolumbar spine /Robert K. Eastlack and Christopher M. Bono --Fractures of the pelvic ring /Adam J. Starr and A. Steven Malekzadeh --Fractures of the acetabulum /Mark C. Reilly --Hip dislocations and fractures of the femoral head /Paul Tornetta III --Fractures of the neck of the femur /Ross K. Leighton --Intertrochanteric fractures /Kenneth J. Koval and Robert V. Cantu --Subtrochanteric fractures /Kwok-sui Leung --Fractures of the shaft of the femur /Sean E. Nork --Fractures of the distal femur /Peter J. OBrien ... [et al.] --Fractures of the patella and injuries to the extensor mechanism /Robert M. Harris --Fractures of the proximal tibia /Kenneth A. Egol and Kenneth J. Koval --Dislocations and fracture-dislocations of the knee /Robert C. Schenck, Jr., James P. Stannard, and Daniel C. Wascher --Fractures of the tibia and fibula /Charles M. Court-Brown --Ankle fractures /J.L. Marsh and Charles L. Saltzman --Fractures of the talus /David W. Sanders --Fractures of the calcaneus /Roy W. Sanders and Michael P. Clare --Fractures and dislocations of the midfoot and forefoot /John S. Early.
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    Biomechanics of fractures and fracture fixation -- Classification of fractures -- The epidemiology of fractures -- Bone and joint healing -- Biological and biophysical technologies for the enhancement of fracture repair -- Principles of nonoperative fracture treatment -- Principles of internal fixation -- Principles of external fixation -- Management of the multiply injured patient -- Initial management of open fractures -- Gunshot and wartime injuries -- Principles of mangled extremity management -- Amputations -- Bone and soft tissue reconstruction -- Outcome studies in trauma -- Imaging considerations in orthopaedic trauma -- Computer-aided orthopaedic surgery in skeletal trauma -- Principles of osteoporosis and fragility fractures -- Stress fractures -- Pathologic fractures -- Periprosthetic fractures -- Systemic complications -- Principles of complex regional pain syndrome -- Orthopaedic infections and osteomyelitis -- Principles of nonunion treatment -- Principles of malunions -- Acute compartment syndrome -- Hand fractures and dislocations -- Carpus fractures and dislocations -- Distal radius and ulna fractures -- Radial and ulnar shaft fractures -- Elbow fractures and dislocations -- Distal humerus fractures -- Humeral shaft fractures -- Proximal humerus fractures -- Clavicle fractures -- Scapular fractures -- Glenohumeral joint subluxations, dislocations, and instability -- Acromioclavicular joint injuries -- Sternoclavicular joint injuires -- Principles of spine trauma care -- Cervical spine fractures and dislocations -- Thoracolumbar spine fractures and dislocations -- Pelvic ring fractures -- Acetabulum fractures -- Hip dislocations and fractures of the femoral head -- Femoral neck fractures -- Intertrochanteric fractures -- Subtrochanteric fractures -- Femoral shaft fractures -- Distal femur fractures -- Patella fractures and extensor mechanism injuries -- Tibial plateau fractures -- Knee dislocations and fracture-dislocations -- Tibia and fibula fractures -- Pilon fractures -- Ankle fractures -- Talus fractures -- Calcaneus fractures -- Fractures and dislocations of the midfoot and forefoot.
  • Incidence of fractures in children / Kaye E. Wilkins and Alaric J. Aroojis -- The biologic aspects of children's fractures / Cory J. Xian and Bruce K. Foster -- Pain relief and related concerns in children's fractures / Joseph R. Furman -- Management of the multiply injured child / Robert M. Kay and Vernon T. Tolo -- Physeal injuries and growth disturbances / Karl E. Rathjen and John G. Birch -- Pathologic fractures associated with tumors and unique conditions of the musculoskeletal system / John P. Dormans and John M. Flynn -- Child abuse / Robert M. Campbell, Jr. and Timothy Schrader -- Fractures and dislocations of the hand and carpus in children / Scott H. Kozin and Peter M. Waters -- Fractures of the distal radius and ulna / Peter M. Waters and Alexander D. Mih -- Injuries to the shafts of the radius and ulna / Charles T. Mehlman and Eric J. Wall -- Fractures of the proximal radius and ulna / Robert E. Eilert and Mark A. Erickson -- Monteggia fracture-dislocation in children / José F. de la Garza --The elbow region: general concepts in the pediatric patient / James H. Beaty and James R. Kasser -- Supracondylar fractures of the distal humerus / James R. Kasser and James H. Beaty -- The elbow: physeal fractures, apophyseal injuries of the distal humerus, osteonecrosis of the trochlea, and t-condylar fractures / James H. Beaty and James R. Kasser -- Dislocations of the elbow / Anthony A. Stans and Stephen D. Heinrich -- Proximal humerus, scapula, and clavicle / John F. Sarwark, Erik C. King, and Scott J. Luhmann -- Cervical spine injuries in children / William C. Warner, Jr. and Daniel J. Hedequist -- Thoracolumbar spine fractures / Peter O. Newton -- Fractures of the pelvis / Roger F. Widmann -- Fractures and traumatic dislocations of the hip in children / R. Dale Blasier and Laurie O. Hughes -- Femoral shaft fractures / James R. Kasser and James H. Beaty -- Extra-articular injuries of the knee / David L. Skaggs -- Intra-articular injuries of the knee / Mininder S. Kocher -- Fractures of the shaft of the tibia and fibula / Stephen D. Heinrich and James F. Mooney III -- Distal tibial and fibular fractures / R. Jay Cummings -- Fractures and dislocations of the foot / James G. Jarvis and Paul J. Moroz.
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    Epidemiology of fractures in children -- The biologic aspects of children's fractures -- Pain relief and related concerns in children's fractures -- Management of the multiply injured child -- Physeal injuries and growth disturbances -- Pathologic fractures associated with tumors and unique conditions of the musculoskeletal system -- The orthopaedic recognition of child maltreatment -- Fractures and dislocations of the hand and carpus in children -- Fractures of the distal radius and ulna -- Injuries to the shafts of the radius and ulna -- Fractures of the proximal radius and ulna -- Monteggia fracture-dislocation in children -- The elbow region: general concepts in the pediatric patient -- Supracondylar fractures of the distal humerus -- The elbow: physeal fractures, apophyseal injuries of the distal humerus, osteonecrosis of the trochlea, and T-condylar fractures -- Dislocation of the elbow -- Proximal humerus, scapula, and clavicle -- Cervical spine injuries in children -- Thoracolumbar spine fractures -- Fractures of the pelvis -- Fractures and traumatic dislocations of the hip in children -- Femoral shaft fractures -- Extra-articular injuries of the knee -- Intra-articular injuries of the knee -- Fractures of the shaft of the tibia and fibula -- Distal tibial and fibular fractures -- Fractures and dislocations of the foot.
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    Innate immunity -- Specific acquired immunity -- Antibodies -- Membrane receptors for antigen -- The primary interaction with antigen -- Immunological methods and applications -- The anatomy of the immune response -- Lymphocyte activation -- The production of effectors -- Control mechanisms -- Ontogeny and phylogeny -- Adversarial strategies during infection -- Vaccines -- Immunodeficiency -- Hypersensitivity -- Transplantation -- Tumor immunology -- Autoimmune diseases.
  • A short introduction to disease emergence /Nicholas Johnson --Patterns of foot-and-mouth disease virus distribution in Africa /Miriam B. Casey [and eleven others] --Paroviruses of carnivores /Andrew B. Allison and Colin R. Parrish --Rabies /Conrad Freuling [and four others] --Lassa fever /Elisabeth Fichet-Calvet --Henipaviruses /Glenn A. Marsh and Lin-Fa Wang --The role of birds in the spread of West Nile virus /Paul Gale and Nicholas Johnson --Rift Valley fever virus /Janusz T. Paweska and Petrus Jansen van Vuren --From simian to human immunodeficiency viruses (SIV to HIV) /Denis M. Tebit and Eric J. Arts --Hantavirus emergence in rodents, insectivores and bats /Mathias Schlegel [and four others] --Nipah virus /David T.S. Hayman and Nicholas Johnson --Synthesis /Philip R. Wakeley, Sarah North and Nicholas Johnson.
  • Mechanisms of apoptosis during reovirus infection /P. Clarke ... [et al.] --Poliovirus, pathogenesis of poliomyelitis, and apoptosis /B. Blondel ... [et al.] --Neuronal cell death in alphavirus encephalomyelitis /D. E. Griffin --HSV-induced apoptosis in herpes encephalitis /L. Aurelian --Therole of apoptosis in defense against baculovirus infection in insects /R. J. Clem --Therole of host cell death in Salmonella infections /D. G. Guiney --Role of macrophage apoptosis in the pathogenesis of Yersinia /Y. Zhang, J. B. Bliska --Entamoeba histolytica activates host cell caspases during contact-dependent cell killing /D. R. Boettner, W. A. Petri --Interactions between malaria and mosquitoes : the role of apoptosis in parasite establishment and vector response to infection /H. Hurd, V. Carter, A. Nacer --Apoptosis and its modulation during infection with Toxoplasma gondii : molecular mechanisms and role in pathogenesis /C. G. K. Luder, U. Gross --Modulation of the immune response in the nervous system by rabies virus /M. Lafon --Apoptotic cells at the crossroads of tolerance and immunity /M. Skoberne ... [et al.].
  • Role of Capsaicin in Cancer Prevention -- Role of Death Receptors Belonging to the TNF Family in Capsaicin-Induced Apoptosis of Tumor Cells -- Role of Capsaicin in Prostate Cancer -- Capsaicin and the Urinary Bladder -- Inhibition of Pancreatitis and Carcinogenesis by Capsaicin -- Cytochrome P450-Dependent Modification of Capsaicinoids: Pharmacological Inactivation and Bioactivation Mechanisms -- The Cancer-Suppressing and -Promoting Actions of Capsaicin -- Oxidative Stress by Capsaicin in Cancer.
  • It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors. However, when the activity of proteases is not regulated appropriately, disease processes can result, as seen in Alzheimer's disease, cancer metastasis and tumor progression, inflammation and atherosclerosis. Thus it is evident that there is an absolute need for a tighter control of proteolytic activities in different cells and tissues. Aimed at graduate students and researchers with an interest in cellular proteolytic events, Role of Proteases in Cellular Dysfunctions is the second book on Proteases in this series. The book consists of three parts in specified topics based on current literatures for a better understanding for the readers with respect to their subject-wise interests. The first section of this book covers a brief idea about the neuronal disorders and the involvement of proteases such as calpains, caspases and matrix metalloproteases (MMPs). The second section covers the deadly disease cancer and its relation to ubiquitin-proteosomal system, MMPs and serine proteases. The last section is about the role of proteases such as calpains, MMPs and serine protease as well as urokinase type plasminogen activator receptor (uPAR) in causing cardiovascular defects.
  • To examine how purchasers and payers interact with the various components of the clinical research enterprise and to understand their perspective on what vision of the enterprise should be.
  • Interdiction of sphingolipid metabolism to improve standard cancer therapies -- Diverse functions of ceramide in cancer cell death and proliferation -- Cermaide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance -- Use of acid sphingomyelinase for cancer therapy -- Hypoxia therapeuric resistance and sphingosine 1-phosphate -- Therapeutic potential of targeting SK1 in human cancers -- Sphinogosine kinase 1 in cancer -- Natural products as platforms for the design of sphingolipid-related anticancer agents.
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  • This book is designed for advanced students and researchers in cell biology, biochemistry, molecular biology, medicine in general, and cancer in particular. It provides the latest data on the transcriptome of the mammary gland in order to establish the molecular and cellular biology of differentiation leading to cancer prevention. The authors have based their work on the epidemiological evidence that early first full term pregnancy is a protective factor in humans against breast cancer and using this knowledge have developed in vivo and in vitro experimental systems that have demonstrated mechanistically how the differentiation takes place. The transcriptoma analysis of the female breast shows that an early first full term pregnancy reprograms the organ by imprinting a genomic signature that differs according to reproductive history. This reprogramming takes place at the chromatin level by changing the transcriptional process. The modification of the transcriptional control is due to the expression of non-coding RNA sequences and post-transcriptional control driven by the spliceosome. The plasticity of the genome of the human breast makes possible this reprogramming that is not only induced by the physiological process of pregnancy but by the use of hormones mimicking pregnancy. The role of stem cells and their reprogramming during differentiation are presented as a new paradigm in breast cancer prevention.
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    V. 1. Introduction and historical bibliography -- Comparative dermatology -- Anatomy and organization of human skin -- Functions of the skin -- Diagnosis of skin disease -- Epidemiology of skin disease -- Histopathology of the skin: general principles -- Molecular biology -- Inflammation -- Clinical immunology, allergy and photoimmunology -- Would healing -- Genetics and genodermatoses -- Prenatal diagnosis of genetic skin disease -- The neonate -- Naevi and other developmental defects -- Pruritus -- Eczema, lichenification, prurigo and erythroderma -- Atopic dermatitis -- Contact dermatitis: irritant -- Contact dermatitis: allergic -- Occupational dermatoses -- Mechanical and thermal injury -- V. 2. Reactions to cold -- Cutaneous photobiology -- Virus infections -- AIDS and the skin -- Bacterial infections -- Mycobacterial infections -- Leprosy -- The treponematoses -- Mycology -- Parasitic worms and protozoa -- Diseases caused by arthropods and other noxious animals -- Disorders of keratinization -- Psoriasis -- Non-melanoma skin cancer and other epidermal skin tumours -- Tumours of the skin appendages -- Disorders of the cutaneous melanocyte --Disorders of skin colour -- Genetic blistering diseases -- Immunobullous diseases -- V. 3. Lichen planus and lichenoid disorders -- Disorders of the sebaceous glands -- Rosacea, perioral dermatitis and similar dermatoses, flushing and flushing syndromes -- Disorders of sweat glands -- Disorders of connective tissue -- Urticaria and mastocytosis -- Purpura and microvascular occlusion -- Vasculitis and neutrophilic vascular reactions -- Diseases of the veins and arteries: leg ulcers -- Disorders of lymphatic vessels -- Histiocytoses -- Soft-tissue tumours and tumour-like conditions -- Cutaneous lymphomas and lymphocytic infiltrates -- Subcutaneous fat -- The 'connective tissue diseases' -- Metabolic and nutritional disorders -- Sarcoidosis -- Systemic disease and the skin -- The skin and the nervous system -- V. 4. Psychocutaneous disorders -- Disorders of nails -- Disorders of hair -- The skin and the eyes -- The external ear -- The oral cavity and lips -- The breast -- The genital, perianal and umbilical regions -- Racial influences on skin disease -- The ages of man and their dermatoses -- General aspects of treatment -- Systemic therapy -- Drug reactions -- Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis -- Topical therapy -- Radiotherapy and reactions to ionizing radiation -- Physical and laser therapies -- Dermatological surgery.
  • Root genomics 2011, Springer
    With the predicted increase of the human population and the subsequent need for larger food supplies, root health in crop plants could play a major role in providing sustainable highly productive crops that can cope with global climate changes. While the essentiality of roots and their relation to plant performance is broadly recognized, less is known about their role in plant growth and development. "Root Genomics" examines how various new genomic technologies are rapidly being applied to the study of roots, including high-throughput sequencing and genotyping, Tilling, transcription.
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    Accompanying CD-ROMs contain all the 4000 illustrations, together with the tables.
  • "This best-selling emergency department reference is now in its thoroughly updated Fourth Edition. The foremost authorities provide practical information on over 600 clinical problems in a fast-access two-page outline format that's perfect for on-the-spot consultation during care in the emergency department. Coverage of each disorder includes clinical presentation, pre-hospital, diagnosis, treatment, disposition, and ICD-10 coding. Icons enable practitioners to quickly spot the information they need. This edition provides up-to-date information on topics such as emerging infections, new protocols, and new treatments"--Provided by publisher.
  • Ch. 1. Anatomy and physiologic morphology -- Ch. 2. Abnormalities of mammary growth and development -- Ch. 3. Inflammatory and reactive tumors -- Ch. 4. Specific infections -- Ch. 5. Papilloma and related benign tumors -- Ch. 6. Myoepithelial neoplasms -- Ch. 7. Adenosis and microglandular adenosis -- Ch. 8. Fibroepithelial neoplasms -- Ch. 9. Ductal hyperplasia: ordinary and atypical -- Ch. 10. Precancerous breast disease: epidemiologic, pathologic, and clinical considerations -- Ch. 11. In Situ (intraepithelial) carcinoma: an overview -- Ch. 12. Staging of breast carcinoma -- Ch. 13. Intraductal carcinoma -- Ch. 14. Invasive duct carcinoma: assessment of prognosis, morphologic prognostic markers, and tumor growth rate -- Ch. 15. Tubular carcinoma -- Ch. 16. Papillary carcinoma -- Ch. 17. Medullary carcinoma -- Ch. 18. Carcinoma with metaplasia -- Ch. 19. Squamous carcinoma -- Ch. 20. Mucinous carcinoma -- Ch. 21. Apocrine carcinoma -- Ch. 22. Mammary carcinoma with endocrine features -- Ch. 23. Small cell (oat cell) carcinoma -- Ch. 24. Secretory carcinoma -- Ch. 25. Mammary carcinoma with osteoclast-like.giant cells -- Ch. 26. Cystic hypersecretory carcinoma and cystic hypersecretory hyperplasia -- Ch. 27. Adenoid cystic carcinoma -- Ch. 28. Cribriform carcinoma -- Ch. 29. Lipid-rich carcinoma -- Ch. 30. Gylcogen-rich carcinoma -- Ch. 31. Invasive micropapillary carcinoma -- Ch. 32. Paget's disease of the nipple -- Ch. 33. Lobular carcinoma In Situ and atypical lobular hyperplasia -- Ch. 34. Invasive lobular carcinoma -- Ch. 35. Unusual clinical presentations of carcinoma -- Ch. 36. Metastases in the breast from nonmammary malignant neoplasms -- Ch. 37. Benign proliferative lesions of the male breast -- Ch. 38. Carcinoma of the male breast -- Ch. 39. Breast tumors in children -- Ch. 40. Benign mesenchymal neoplasms -- Ch. 41. Sarcoma -- Ch. 42. Lymphoid and hematopoietic tumors -- Ch. 43. Pathologic effects of therapy -- Ch. 44. Cutaneous neoplasms -- Ch. 45. The pathology of axillary and intramammary lymph nodes -- Ch. 46. Pathologic examination of breast and lymph node specimens.
  • Anatomy and physiologic morphology -- Abnormalities of mammary development and growth -- Inflammatory and reactive tumors -- Specific infections -- Papilloma and related benign lesions -- Myoepithelial neoplasms -- Adenosis and microglandular adenosis -- Fibroepithelial neoplasms -- Ductal hyperplasia: usual and atypical -- Precarcinomatous breast disease: epidemiologic, pathologic, and clinical considerations -- Ductal carcinoma In Situ -- Invasive ductal carcinoma: assessment of prognosis with morphologic and biologic markers -- Tubular carcinoma -- Papillary carcinoma -- Medullary carcinoma -- Carcinoma with metaplasia and low-grade adenosquamous carcinoma -- Squamous carcinoma -- Mucinous carcinoma -- Apocrine carcinoma -- Mammary carcinomas with endocrine features -- Small cell carcinoma -- Secretory carcinoma -- Mammary carcinoma with osteoclast-like giant cells -- Cystic hypersecretory carcinoma and cystic hypersecretory hyperplasia -- Adenoid cystic carcinoma -- Invasive cribriform carcinoma -- Lipid-rich carcinoma -- Glycogen-rich carcinoma -- Invasive micropapillary carcinoma -- Paget disease of the nipple -- Lobular carcinoma In Situ and atypical lobular hyperplasia -- Invasive lobular carcinoma -- Unusual clinical presentation of carcinoma -- Metastases in the breast from nonmammary neoplasms -- Benign proliferative lesions of the male breast -- Carcinoma of the male breast -- Breast tumors in children -- Benign mesenchymal neoplasms -- Sarcoma -- Lymphoid and hematopoietic neoplasms of the breast -- Pathologic effects of therapy -- Cutaneous neoplasms -- The pathology of axillary and intramammary lymph nodes -- Pathologic examination of breast and lymph node specimens, including sentinel lymph nodes -- Molecular classification and testing of breast carcinoma.
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  • Fundamental clinical concepts -- Critical management principles -- Cardinal presentations -- Trauma -- General concepts -- System injuries -- Orthopedic lesions -- Soft tissue injuries -- Violence and abuse -- Medicine and surgery -- Head and neck disorders -- Pulmonary system -- Cardiac system -- Vascular system -- Gastrointestinal system -- Genitourinary and gynecologic systems -- Neurology -- Psychiatric and behavioral disorders -- Immunologic and inflammatory -- Hematology and oncology -- Metabolism and endocrinology -- Infectious diseases -- Environment and toxicology -- Environment -- Toxicology -- Special populations -- The pediatric patient -- The pregnant patient -- The geriatric patient -- The patient with compromised immune function -- The patient with an organ transplant -- The alcoholic and substance abuse patient -- The developmentally or physically disabled patient -- The problem patient -- Emergency medical services -- The practice of emergency medicine -- Bonus online content -- Youth, violence, and street gangs -- Medical literature and evidence-based medicine -- Multiculturalism and care delivery -- Bioethics -- End of life -- Emergency medical treatment and active labor act and medicolegal issues -- Wellness, stress, and the impaired physician.
  • Rotator cuff tear 2012, Karger
    Epidemiology, genetics, and biological factors of rotator cuff tears / Longo, U.G. ... [et al.] -- Biomechanics of the rotator cuff : European perspective / Longo, U.G. ... [et al.] -- Role of biomechanics in rotator cuff pathology : North American perspective / Karas, V.; Cole, B.J.; Wang, V.M. -- The scapula in rotator cuff disease / Ben Kibler, W. -- Instability and rotator cuff tear / Porcellini, G. ... [et al.] -- Growth factors and tendon healing / Oliva, F. ... [et al.] -- Autologous blood products in rotator cuff repair / Mei-Dan, O.; Carmont, M.R. -- Tendinopathy of the long head of the biceps / Snyder, G.M.; Mair, S.D.; Lattermann, C. -- Conservative treatment and rotator cuff tear progression / Longo, U.G. ... [et al.] -- Operative management of partial- and full-thickness rotator cuff tears -- Franceschi, F. ... [et al.] -- Subscapularis tears / Longo, U.G. ... [et al.] -- Single- and double-row repair for rotator cuff tears -- biology and mechanics / Papalia, R. ... [et al.] -- Arthroscopic transosseous rotator cuff repair / Longo, U.G. ... [et al.] -- Treatment options for chronic retracted degenerative rotator cuff tears / Deering, S.J.; Mair, S.D.; Lattermann, C. -- Synthetic augmentation in massive rotator cuff tears / Longo, U.G. ... [et al.] -- Understanding and preventing complications in repairing rotator cuff tears / Osti, L. ... [et al.].
  • Rotaviruses Springer Protocols
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    V. I. Basic science. Diagnosis. Surgical anatomy and surgical approaches. Spinal fusion and instrumentation. The child's spine. Arthritis and inflammatory disorders -- V. II. Cervical degenerative disorders. Thoracic and lumbar disc disease. Spinal stenosis. Adult deformity. Spine trauma. Afflictions of the vertebrae. Spinal cord. Complications. Failed surgery. Rehabilitation.
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    v. 1. Basic science -- Diagnosis -- Surgical anatomy and approaches -- The child's spine -- Arthritis and inflammatory disorders -- Cervical degenerative disorders -- Thoracic and lumbar disc disease -- Minimally invasive surgery -- v. 2. Spinal stenosis -- Spinal fusion and instrumentation -- Adult deformity -- Spine trauma -- Afflictions of the vertebrae -- Spinal cord -- Complications -- Failed surgery -- Chronic pain/rehabilitation.
  • Rotifera X 2005, Springer
  • RT-PCR protocols 2002, Springer Protocols
  • Rubella viruses 2007, ScienceDirect
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    Inflammation / Hedwig S. Murphy -- Repair, regeneration, and fibrosis / Gregory C. Sephel, Stephen C. Woodward -- Immunopathology / Jeffrey S. Warren, Douglas P. Bennett, Roger J. Pomerantz -- Neoplasia / Antonio Giordano ... [et al.] -- Developmental and genetic diseases / Anthony A. Killeen, Emanuel Rubin, David S. Strayer -- Hemodynamic disorders / Bruce M. McManus, Michael F. Allard, Robert Yanagawa -- Environmental and nutritional pathology / David S. Strayer, Emanuel Rubin -- Infectious and parasitic diseases / David A. Schwartz ... [et al.] -- Blood vessels / Avrum I. Gotlieb -- The heart / Jeffrey E. Saffitz -- The respiratory system / Mary Beth Beasley, William D. Travis, Emanuel Rubin -- The gastrointestinal tract / Frank A. Mitros, Emanuel Rubin -- The liver and biliary system / Raphael Rubin, Emanuel Rubin -- The pancreas / Gregory Y. Lauwers, Mari Mino-Kenudson, Raphael Rubin -- The kidney / J. Charles Jennette -- The lower urinary tract and male reproductive system / Ivan Damjanov -- The female reproductive system / Stanley J. Robboy, Maria J. Merino, George L. Mutter -- The breast / Ann D. Thor, Adeboye O. Osunkoya -- Hematopathology / Roland Schwarting, Steven McKenzie, Raphael Rubin -- The endocrine system / Maria Merino ... [et al.] -- Obesity, diabetes mellitus, metabolic syndrome / Barry J. Goldstein, Serge Jabbour, Kevin Furlong -- The amyloidoses / Robert Kisilevsky -- The skin / Craig A. Storm, David E. Elder -- The head and neck / Bruce M. Wenig -- Bones and joints / Benjamin L. Hoch, Michael J. Klein, Alan L. Schiller -- Skeletal muscle / Lawrence C. Kenyon, Mark T. Curtis -- The nervous system / John Q. Trojanowski, Lawrence Kenyon, Thomas W. Bouldin -- The eye / Gordon K. Klintworth -- Cytopathology / Hormoz Ehya, Marluce Bibbo.
  • Ruby in a nutshell 2002, ProQuest Safari
  • Ruby programming language. 1st ed. SU Catalog (SearchWorks), Click LINK above for location/circulation status.
    Print Material
  • Rural surgery 2011, Springer
  • Russische Karrieren-- Leibärzte im 19. Jahrhundert SU Catalog (SearchWorks), Click LINK above for location/circulation status.
    Print Material
    Includes 80 biobibliographies of German, Baltic and Russian personal physicians.
  • Part 1. Personal Views -- A Personal View / James M. Ryan -- A Personal Experience / Damian Douglas Keene -- The War in West Philadelphia / John P. Pryor -- Part 2. Weapons, Blast and Ballistics -- How Guns Work / Mark Byers, Kerry Starkey and Peter F. Mahoney -- The Effects of Bullets / Donald H. Jenkins -- Bombs, Mines, and Fragmentation / Toney W. Baskin and John B. Holcomb -- Cluster Munitions / Henry Dowlen -- Shaped Charges and Explosively Formed Projectiles / Jonathan Morrison and Peter F. Mahoney -- Suicide Bombs / Piers R. J. Page and Ian Greaves -- Blast Injury / Emrys Kirkman, Neal Jacobs, Giles R. Nordmann, Stuart Harrisson and Peter F. Mahoney, et al. -- Ballistic Protection / Alan Hepper, Daniel Longhurst, Graham Cooper and Philip Gotts -- Forensic Aspects of Ballistic Injury / Jeanine Vellema and Hendrik Scholtz -- Part 3. Trauma Systems -- Civilian Trauma Systems / Jason Smith -- The UK Military Trauma System / Timothy J. Hodgetts -- Part 4. Prehospital and the Emergency Room -- Triage / Rob Russell -- Prehospital Care / Mark Byers, John-Joe Reilly and Peter F. Mahoney -- Emergency Department Management / Jason Smith -- Imaging Triage for Ballistic Trauma / Jon David Simmons and Tracy R. Bilski -- Part 5. Advanced Resuscitation and Anaesthesia, Section -- Damage Control Resuscitation / Adam J. Brooks and Bryan A. Cotton -- Battlefield Analgesia / Aaron D. Nelson and Dominic J. Aldington -- Anesthesia for the Ballistic Casualty / Craig C. McFarland -- Regional Anesthesia for the Ballistic Trauma Victim / Dan Connor --Part 6. Clinical Care -- Damage Control Surgery: Concepts / Mark J. Midwinter and Adam J. Brooks -- Management of Ballistic Trauma to the Head / Geoffrey S. F. Ling, Chris J. Neal and James M. Ecklund -- Spinal Injury / Neil Buxton -- Eyes / Robert A. H. Scott -- Maxillofacial Ballistic Injuries / Andrew Martin Monaghan -- Neck Injury / Matthew J. Borkon and Bryan A. Cotton -- Damage Control / Benjamin Braslow, Adam J. Brooks and C. William Schwab -- Management of Vascular Trauma / Kate Brown and Nigel Tai -- Damage Control Part III: Definitive Reconstruction / Steven R. Allen, Adam J. Brooks, Patrick M. Reilly and Bryan A. Cotton -- Penetrating Genitourinary Trauma / Jay J. Doucet and David B. Hoyt -- Burns / Alan Kay -- Management of Extremity Injuries / David E. Hinsley and Jon Clasper -- Ballistic Trauma in Children / Graeme Pitcher -- Ballistic Trauma in Pregnancy / Michael J. Socher and Peter E. Nielsen -- Managing Ballistic Injury in the NGO Environment / Ari K. Leppäniemi -- Part 7. Critical Care -- Critical Care for Ballistic Trauma in Austere Environments / Christian B. Swift and Geoffrey S. F. Ling -- Transfer and Evacuation / Robert D. Tipping and Jonathan Vollam -- Critical Care Management: The Patient with Ballistic Trauma / Tim Nutbeam and Damian Douglas Keene -- Critical Care Nursing at Role Four / Clare Dutton -- The Role of Nutrition in the Treatments of Injured Military Personnel / Susan Duff, Susan Price and Jennifer Gray -- Part 8. Reconstruction & Rehabilitation -- Role 4 and Reconstruction / Steven L. A. Jeffery and Keith Porter -- Conflict Rehabilitation / John Etherington -- Part 9. And Finally -- Have You Read MASH? / Peter F. Mahoney.
  • Ryanodine receptors 2005, Springer
all 577 "R" titles

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Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides one-click access to important clinical resources; includes evidence-based diagnosis and treatment guidelines, Books, EBM articles, Ovid MEDLINE, Drug facts and comparisons, Drug interaction facts, guidelines from National Guideline Clearinghouse, patient handouts (English and Spanish), and local content.MD consult provides access to textbooks, electronic journals, practice guidelines, drug information, and patient education handouts.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.