Books
- The R primer. Second edition. — The Real doctor will see you shortly : a physician's first year. First edition [1st ed.]. (171)
- Real life — Renal cancer-- contemporary management. Second edition. (171)
- Renal cancer : current status and innovations — Rhinitis and related upper respiratory conditions : a clinical guide (171)
- Rhino-orbito-cerebral mucormycosis — Ryan's Retina. Seventh edition. (171)
- DigitalNishi Gupta, Santosh G. Honavar, editors.Summary: This book is the most comprehensive (and possibly the first) manual on Rhino-Orbito-Cerebral Mucormycosis (ROCM) that covers mucormycosis of the nose extending to sinuses, orbit, and brain, all in. This volume covers the surge of cases during the COVID-19 pandemic, early identification and causative factors, microbiology, pathology and radiology, and the clinical presentation. Notes on surgical approaches, extent, and techniques of debridement, number of sittings, antifungal therapy, complications, and their management equip readers to manage these cases confidently. Detailed descriptions of ROCM surgery accompanied by nearly 500 photographs and anatomical drawings help support diagnostic and surgical decision-making. Also included is information on various specifications of MRI that help in achieving a perfect surgical clearance. The book includes chapters on debates on salvaging the orbit in ROCM, various situations, their management, the extent of resection, antifungal dosage and duration, prognostication of the patient, and postoperative care. The book assists surgeons in gaining the skills to perform endoscopic clearance of difficult areas like pterygoplataine fossa, infratemporal fossa, pterygoid plates, and the lacrimal drainage system, which offers significant advantages in terms of avoiding postoperative morbidity as compared to an external route. Since the external route is required in the most extensive form of the disease, the book has also covered it extensively. This book is an indispensable resource for otorhinolaryngologists, ophthalmic surgeons, ophthalmic plastic surgeons, physicians, microbiologists, pathologists, radiologists, neurosurgeons, faciomaxillary surgeons and junior and senior consultants optometrists and students.
- DigitalMarios Stavrakas, Hisham S. Khalil, editors.Summary: This book offers a selection of pertinent patient case-presentations in the field of Rhinology, Anterior Skull Base and Facial Plastics surgery. It further explores the evidence-based management of simple to complex clinical presentations. Each chapter start with the diagnosis and progresses from medical or surgical treatment to the post-operative follow up of the presented clinical condition. The various case reports are concise; however, sufficiently comprehensive and cover conditions from emergencies in adult and paediatric rhinology, to elective care, sino-nasal and anterior skull base neoplasms systemic diseases affecting the nose and paranasal sinuses, and underpinned by illustrations, imaging, and intra-operative photographs to emphasize the clinical approach. Rhinology and Anterior Skull Base Surgery - A Case-based Approach is a highly informative and carefully presented book, providing insights for exam candidates, trainees, general practitioners, rhinologists and otolaryngologists with an interest in anterior skull base, facial plastics and rhinology.
Contents:
Introduction
Emergencies in Rhinology
Rhinitis
Rhinosinusitis
Facial plastics
Anterior skull base surgery.-Sinonasal tumours.-Paediatric rhinology
Olfactory disorders
Systematic diseases affecting the nose and the paranasal sinuses
General rhinology
Post- operative complications. - Digital[edited by] Husain Ali Khan, James D. Frame, Shahrokh C. Bagheri, Behnam Bohuli ; consulting editor, Foad Nahai.Digital Access ClinicalKey 2023
- DigitalRollin K. Daniel, Péter Pálházi.Summary: In this atlas, sequential anatomical dissections are presented which show each component of the nose in unprecedented meticulous detail. Anatomical photographs are often paired with anatomical drawings and even intraoperative clinical photographs to illustrate each part of the nose. Rhinoplasty: An Anatomical and Clinical Atlas, provides an in-depth understanding of nasal anatomy and a wide variety of operative techniques. In rhinoplasty surgery, the surgeon must understand the tight linkage between surface aesthetics, underlying anatomy, and selection of operative techniques. The underlying anatomy is only revealed to a limited degree at the time of surgery and the surgeon must then adapt the operative plan to fit the actual anatomy observed in the operating room to achieve the patient's desired aesthetic result. Ultimately, the goal of this atlas is to allow the surgeon to see the operative techniques in both cadavers and clinical cases which represents the best possible learning approach.Digital Access Springer 2018
- Digital[edited by] Anthony P. Sclafani, MD, FACS, Surgeon Director, Director of Facial Plastic Surgery, the New York Eye and Ear Infirmary of Mount Sinai, Professor of Otolaryngology, Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, New York.Summary: "Rhinoplasty: The Experts Reference is a comprehensive text that provides guidance from world-renowned experts on every aspect of rhinoplasty, from the functional to the cosmetic. The book opens with a section on initial patient assessment and consultation, moves on to such topics as surgery of the septum, with separate sections on the nuances of functional nasal surgery and revision rhinoplasty, and concludes with a section on avoiding and managing surgical complications. Each chapter is written by an expert on a specific topic and presents tried-and-true rhinoplasty techniques that can be readily implemented by facial plastic surgeons. Key Features: includes a section on ethnic rhinoplasty with chapters written by Drs. Tae-Bin Won, Russell W.H. Kridel, and Roxana Cobo; written by over 100 of the most well-known surgeons in the world, including Yong Ju Jang (Asia), Ira Papel, Stephen Park, Peter Adamson, and Rollin K. Daniel (North America), Wolfgang Gubisch, Charles East, Gilbert Nolst Trenite, and Pietro Palma (Europe), and Simon Robinson (Australia); Oofers expert solutions to a particular problem in each chapter. Practicing plastic surgeons and facial plastic surgeons, as well as residents and fellows in these fields, will consult this excellent desk reference whenever they are faced with a particularly challenging case"-- Provided by publisher.Digital Access
- Digitalvolume editors, Bradford A. Woodworth, David M. Poetker, Douglas D. Reh.Contents:
Differential diagnosis of chronic rhinosinusitis with nasal polyps
Allergic fungal rhinosinusitis: the latest in diagnosis and management
Aspirin exacerbated respiratory disease
Cystic fibrosis sinusitis
Influence of P-glycoprotein function on chronic rhinosinusitis/nasal polyps pathophysiology
B-cells and antibody-mediated pathogenesis in chronic rhinosinusitis with nasal polyps
Innate lymphoid cells: the innate counterpart to T helper cells
The role of innate immunity and aeroallergens in chronic rhinosinusitis
Acquired cystic fibrosis transmembrane conductance regulator deficiency
Role of Vitamin D in pathogenesis of chronic sinusitis with nasal polyposis
Taste receptors in upper airway immunity
Immunomodulators in the treatment of nasal polyposis
Delivery of topical therapies
Topical steroids
Implantable devices/drugs in the management of nasal polyps
Oral therapeutics for rhinosinusitis with nasal polypsis
Advances in surgery: extended procedures for sinonasal polyp disease
Outcomes in medical and surgical treatment of nasal polyps
Author index
Subject index.Digital Access Karger 2016 - DigitalNitin M. Nagarkar, Rupa Mehta, editors.Summary: This textbook covers all aspects of rhinosporidiosis known till date and puts forward the various aspects of the disease on which further research can be carried out. Detailed descriptions of varied presentations of rhinosporidiosis managed at our institute is provided, accompanied by numerous clinical and intraoperative photographs. This book will serve as a comprehensive source of information related to all aspects of rhinoporidiosis. Experts from multiple specialties have contributed about aspects pertaining to their specialties.
Contents:
1. Introduction
2. Microbiological aspects
3. Epidemiology
4. Clinical presentation- ENT aspects- 5. Clinical presentation- ophthalmological aspects
6. Clinical presentation cutaneous manifestations
7. Investigations
8. Surgical management
9. Pharmacological management
10. Pathological aspects
11. Immunological aspects
12. Our experience
13. Research topics. - Digitaledited by David A. Jans, Monash University, Melbourne, VIC, Australia, Reena Ghildyal, University of Canberra, ACT, Australia.Contents:
Classification and evolution of human rhinoviruses / Ann C. Palmenberg and James E. Gern
Nested-RT-PCR and multiplex RT-PCR for diagnosis of rhinovirus infection in clinical samples / Xuelian Yu and Reena Ghildyal
Molecular identification and quantification of human rhinoviruses in respiratory samples / Wai-Ming Lee ... [et al.]
Molecular genotyping of human rhinovirus by using PCR and sanger sequencing / Wei Wang ... [et al.]
Growth of human rhinovirus in H1-HeLa cell suspension culture and purification of virions / Wai-Ming Lee ... [et al.]
Propagation of rhinovirus-C strains in human airway epithelial cells differentiated at air-liquid interface / Shamaila Ashraf, Rebecca Brockman-Schneider, and James E. Gern
Infectivity assays of human rhinovirus-A and -B serotypes / Wai-Ming Lee ... [et al.]
Application of FCS in studies of rhinovirus receptor binding and uncoating / Shushan Harutyunyan ... [et al.]
Capillary electrophoresis, gas-phase electrophoretic mobility molecular analysis, and electron microscopy : effective tools for quality assessment and basic rhinovirus research / Victor U. Weiss ... [et al.]
Proteases of human rhinovirus : role in infection / Lora M. Jensen ... [et al.]
Protocol to express and isolate HRV16 3C protease for use in protease assays / Lora M. Jensen, Erin J. Walker, and Reena Ghildyal
Reverse genetics system for studying human rhinovirus infections / Wai-Ming Lee ... [et al.]
Reverse genetic engineering of the human rhinovirus serotype 16 genome to introduce an antibody-detectable tag / Erin J. Walker, Lora M. Jensen, and Reena Ghildyal
Mouse models of rhinovirus infection and airways disease / Nathan W. Bartlett, Aran Singanayagam, and Sebastian L. Johnston.Digital Access Springer 2015 - DigitalVadakattu V.S.R. Gupta, Anil K. Sharma, editors.Summary: This book presents a detailed discussion on the direct interactions of plants and microorganisms in the rhizosphere environment. It includes fifteen chapters, each focusing on a specific component of plant-microbe interactions, such as the influence of plants on the root microbiome, and the downstream effects of rhizosphere microbial dynamics on carbon and nutrient fluxes in the surroundings. As such, the book helps readers gain a better understanding of diversity above the ground, and its effect on the microbiome and its functionality.
Contents:
Bacterial Endophytes: Diversity, Functional Importance, and Potential for Manipulation.
Rhizosphere Carbon Turnover from Cradle to Grave: The Role of Microbe-Plant Interactions.
Root-Soil-Microbe Interactions Mediating Nutrient Fluxes in the Rhizosphere.
Diazotrophic Nitrogen Fixation in the Rhizosphere and Endosphere.
Root Microbiome Structure and Microbial Succession in the Rhizosphere.
Rhizosphere Legacy: Plant Root Interactions with the Soil and Its Biome.
Rhizosphere Microbiome and Soil-Borne Diseases.
Root Disease Impacts on Root-Rhizosphere Microbial Communities.
Newly Introduced or Modified Genes in Plants Potentially Modulate the Host Microbiome.
Rhizosphere Plant-Microbe Interactions Under Abiotic Stress.
Arbuscular Mycorrhizal Fungi Interactions in the Rhizosphere.
Microbial-Faunal Interactions in the Rhizosphere.
Inter-Organismal Signaling in the Rhizosphere.
Molecular Mechanisms of Plant-Microbe Interactions in the Rhizosphere as Targets for Improving Plant Productivity.
Inoculation Effects in the Rhizosphere: Diversity and Function. - Digitaledited by Beata Jastrzebska.Contents:
G protein-coupled receptor rhodopsin : a historical perspective / Lukas Hofmannand Krzysztof Palczewski
Rhodopsin purification from dark-adapted bovine retina / Elise Blankenship and David T. Lodowski
Mammalian expression, purification, and crystallization of rhodopsin variants / Daniel Mattle [and 4 others]
Imaging of rhodopsin crystals with two-photon microscopy / Grazyna Palczewska and David Salom
Functional stability of rhodopsin in a bicelle system : evaluating G protein activation by rhodopsin in bicelles / Ali I. Kaya, T.M. Iverson, and Heidi E. Hamm
Rhodopsin-arrestin-1 interaction in bicelles / Qiuyan Chen [and 7 others]
Detection of structural waters and their role in structural dynamics of rhodopsin activation / Liwen Wang and Mark R. Chance
Probing conformational changes in rhodopsin using hydrogen-deuterium exchange coupled to mass spectrometry / Tivadar Orban and Yaroslav Tsybovsky
Analysis of conformational changes in rhodopsin by histidine hydrogen-deuterium exchange / David T. Lodowski and Masaru Miyagi
Investigation of rhodopsin dynamics in its signaling state by solid-state deuterium NMR spectroscopy / Andrey V. Struts [and 3 others]
Sequential structural changes in rhodopsin occurring upon photoactivation / Naoki Kimata [and 4 others.]
Dynamic single-molecule force spectroscopy of rhodopsin in native membranes / Paul S.-H. Park and Daniel J. Müller
High-resolution atomic force microscopy imaging of Rhodopsin in rod outer segment disk membranes / Patrick D. Bosshart, Andreas Engel, and Dimitrios Fotiadis
Detection of rhodopsin dimerization in situ by PIE-FCCS, a time-resolved fluorescence spectroscopy / Adam W. Smith
Oligomeric state of rhodopsin within rhodopsin-transducin complex probed with succinylated concanavalin A / Beata Jastrzebska
Quantification of arrestin-rhodopsin binding stoichiometry / Ciara C.M. Lally and Martha E. Sommer
Rhodopsin transient complexes investigated by systems biology approaches / Daniele Dell'Orco
Three-dimensional architecture of murine rod cilium revealed by cryo-EM / Theodore G. Wenseland Jared C. Gilliam
Monitoring of rhodopsin trafficking and mistrafficking in live photoreceptors / Kerrie H. Lodowski and Yoshikazu Imanishi
Measurements of rhodopsin diffusion within signaling membrane microcompartments in live photoreceptors / Mehdi Najafi and Peter D. Calvert
Kinetics of rhodopsin's chromophore monitored in a single photoreceptor / Leopold Adler IV [and 3 others]
Supplementation with vitamin A derivatives to rescue vision in animal models of degenerative retinal diseases / Lindsay Perusek, Akiko Maeda, and Tadao Maeda
Sustained delivery of retinoids to prevent photoreceptor death / Peter H. Tang and Rosalie K. Crouch
High-throughput screening assays to identify small molecules preventing photoreceptor degeneration caused by the rhodopsin P23H mutation / Yuanyuan Chen and Hong Tang
Gene therapy to rescue retinal degeneration caused by mutations in rhodopsin / Brian P. Rossmiller, Renee C. Ryals, and Alfred S. Lewin.Digital Access Springer 2015 - DigitalMaria Peris-Celda, Francisco Martinez-Soriano, Albert L. Rhoton, Jr. ; anatomical labeling, Alfonso Amador Valverde, Vicent Teruel Marti.Digital Access
- Digitaledited by James R. Evans, Robert P. Turner.Summary: Rhythmic Stimulation Procedures in Neuromodulation offers a unique approach to rhythm-related stimulation as it pertains to modulating neural functioning, with the goal of alleviating symptoms of mental disorder. Rhythm and related concepts (frequency, resonance, entrainment) are thought by many to be closely linked to human health and disease. Neurologists and clinical psychologists facilitate neuroplasticity by using pulsed (rhythmic) sensory or electromagnetic stimulation-a group of techniques broadly referred to as neuromodulation. This edited volume describes details of rhythm-related neuromodulation techniques, and experts in the field have detailed the pros and cons of each approach, citing both clinical and scientific support. Each technique chapter provides a detailed description of the procedure, a rationale for application with specific populations, discussion of similarities/differences relative to other approaches, and support for efficacy. This volume offers readers a historical overview of the roles of rhythm and dysrhythmia in health and disease, including examples of past and present therapeutic uses of rhythmic stimulation, entrainment, and/or modification. It also facilitates speculation about potential developments in rhythm-related methods for the future of mental health. Few books published in the general area of rhythm have focused on the scientific study of the significance of biological rhythms.
Contents:
Historical overview of rhythmic stimulation procedures in health and disease / James R. Evans
Cranio-electro stimulation: an effective yet simple technique for calming the mind / Dane Siever
Audio-visual entrainment: physiological mechanisms and clinical outcomes / Dane Siever, Tom Collura
Photobiomodulation and other lightstimulation procedures / Marvin H. Berman, Michael R. Hamblin, Paul Chazot
Nexalin and related forms of subcortical electrical stimulation / Nancy E. White, Leonard M. Richards
The use of music for neuromodulation / Eric Miller, Lynn Miller, Robert P. Turner, James R. Evans
Noninvasive transcranial magnetic and electrical stimulation: working mechanisms / Dirk De Ridder, Theresia Stöckl, Wing Tin To, Berthold Langguth, Sven Vanneste
Toward a frequency-based theory of neurofeedback / Siegfried Othmer, Susan F. Othmer
Cultural factors in responses to rhythmic stimuli / Udo Will
Speculation on the nature and future of rhythmic stimulation / James R. Evans.Digital Access ScienceDirect 2017 - DigitalJ. Anthony Gomes.Summary: This book provides an overview of the history, manifestations, and treatment of heart disease and heart rhythm disorders. In addition, it covers the effects on the lives of patients, coping mechanisms, and relationships with doctors, family, religion, and death. The book uniquely intersects the fields of medicine, literature, science, and art. Chapters begin by familiarizing the reader with the historical aspects of manifestations and treatment discussing both scientific and psychological aspects of the disease. Chapters also discuss the evolution of several treatment modalities. Every chapter of the book contains interesting and evocative patient stories and their treatment. Rhythms of Broken Hearts will be of interest to a wide spectrum of health care practitioners as well as to patients and related family members with interest in understanding their symptoms and disease entity.
Contents:
Intro
Praise for Rhythms of Broken Hearts
Books by J. Anthony Gomes, MD
Author's Note
Preface
Acknowledgments
Contents
Part I: The Mythology of the Human Heart
Chapter 1: Romanticizing the Heart
Ancient Egyptian View of the Heart
Ancient Indian View of the Heart
Ancient Greek View of the Heart
Ancient Islamic View of the Heart
The Renaissance Heart
William Harvey's View of the Heart
The Heart as Metaphor
Chapter 2: The Mysteries of the Age-Old Pulse
The Rosetta Stone of Ancient Egyptian Medicine Classifying the Pulse: Ancient Asian Medicine
Dissections and Clepsydras: The Ancient Greeks and Romans
Avicenna and Maimonides
The Pulsilogium and the Stopwatch
Current Understanding of the Pulse
Conclusions
Part II: The Renaissance Period in Heart Rhythm Disorders
Chapter 3: Demystifying the Heart
The Cartography of the Heart
The Search for the Command Center
The Org Chart of Control
Inside the Command Fibers
Chapter 4: Understanding Heart Rhythm Disorders: The Birth of the ECG and Clinical Cardiac Electrophysiology
The Code of the Electrocardiogram (ECG) Starting and Stopping Heartbeats
Tapping the Signals From Within the Heart
Enter Dr. Benjamin Scherlag, Ph.D.
The USPHS Hospital and Its Electrophysiology Laboratory
Dr. Anthony N. Damato: The Grandfather of Clinical Electrophysiology
Part III: Galloping Away in the Atrium
Chapter 5: Living with a Galloping Heart
George Ralph Mines and the Circles of PSVT
Maria's PSVT
Identifying Maria's Syndrome
What Causes WPW Syndrome?
Maria's Life-Threatening Complication
The Commonest Supraventricular Tachycardia
The Case of Antoinette Chapter 6: Radical Ideas: The Road to Conquering Supraventricular Tachycardia
The Road to Ending PSVT
The Attempt to Save Diane
Catheters and Radio Waves
Diane and Her Secret Companion
Antoinette's Curative Ablation of AVNRT
The Management of AVNRT
Chapter 7: Atrial Fibrillation: The Heart's Tap Dance
Triggers and Genes
The Cost of Atrial Fibrillation
The Insidious Upshots of Atrial Fibrillation
Evolution of Clot Prevention in AF Treatment
The Story of Warfarin
The New Anticoagulants
Preventing Strokes in Patients with AF New Devices for Stroke Prevention
Evolution of Rhythm and Rate Control in AF
Cardioversion
The Story of Maze
Medical Societies and Their Guidelines
Ablation: Fire and Ice
Treating Marjorie
Chapter 8: The Sawtooth Rhythm: Atrial Flutter
The Story of the Purple Foxglove (Digitalis)
The Road to Definitive Treatment
Part IV: Abnormal Rhythms Arising from the Ventricles
Chapter 9: The Elusive Ventricular Extra-Beat
The Origins of VPCs
Martha: Anxiety Versus VPCs
The Rock and the Mountain
VPC-Induced Cardiomyopathy - DigitalMarc de Moya, John Mayberry, editors.Summary: This text fills the educational gap for those trauma, orthopedic, and thoracic surgeons interested in learning the cutting edge evidence-based approaches to treatment of rib fractures. Although there has been ever increasing levels of interest and experience nationally there are many questions which remain. This text will provides not only the theoretical background for improving outcomes in those with rib fractures but also serve as a practical guide to those interested in starting new programs. The text includes tips and tricks that can be used in the operating room, or at the bedside to improve patient care. Therefore, the focus will be on a comprehensive review but also including tips and tricks from the most experienced surgeons around the country who are performing internal fixation for rib fractures. Rib Fracture Management .
Contents:
History of Rib Fracture Management
Chest Wall Anatomy
Pathophysiology of Rib Fractures and Lung Contusion
Scoring Systems of Blunt Thoracic Trauma and Rib Fractures
Medical Management of Rib Fractures
Lung Contusion Management: Invasive and Noninvasive
Rib Fracture and Lung Contusion: Impact on Pulmonary Function Tests
Indications for Rib Fixation
Slipping Rib Syndrome and Other Causes of Chest Wall Pain
Rib Fracture Management Algorithm for the Traumatically Injured, Non-intubated Patient
Non-Union
Operative Techniques
Review of Currently Available Tools of the Trade
Postoperative Complications After Rib Fracture Repair
Billing and Coding
Future Directions. - Digitaledited by Donald H. Burke-Aguero.Summary: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in riboswitch discovery and validation, synthesis and sample prep methods for large RNAs, riboswitch structure and function methods, folding pathways and dynamics, and ligand interactions and thermodynamics.Continues the legacy of this premier serial with quality chapters authored by leaders in the fieldCovers research methods in biomineralization scienceContains sections on such topics as riboswitch discovery and valid.
Contents:
Riboswitch discovery by combining RNA-seq and genome-wide indentification of transcriptional start sites
Discoverying human RNA aptamers by structure-based bioinformatics and genome-based in vitro selection
Affinity purification of in vitro transcribed RNA with homogenous ends using a 3'-ARiBo tag
Deoxyribozyme-mediated ligation for incorporating EPR spin labels and reporter groups into RNA
A flexible, scalable method for preparation of homogenous aminoacylated tRNAs
Synthesis of a biotinylated photocleavable nucleotide monophosphate for the preparation of natively folded RNAs
Chemo-enzymatic synthesis of selectively 13C/15N-labeled RNA for NMR structural and dynamics studies
SHAPE analysis of small RNAs and riboswitches
Experimental approaches for measuring pKa's in RNA and DNA
Crystallographic analysis of TPP riboswitch binding by small-molecule ligands discovered through fragment-based drug discovery approaches
Methods for using new conceptual tools and parameters to assess RNA structure by small-angle X-ray scattering
Use of 19F NMR methods to probe conformational heterogeneity and dynamics of exchange in functional RNA molecules
Site-directed spin-labeling strategies and electron paramagetic resonance spectroscopy for large riboswitches
Using sm-FRET and denaturants to reveal folding landscapes
Riboswitch structure and dynamics by smFRET microscopy
Ribosome structure and dynamics by smFRET microscopy
Unraveling the thermodynamics and kinetics of RNA assembly: surface plasmon resonance, isothermal titration calorimetry, and circular dichroism
ITC analysis of ligand binding to PreQ1 riboswitches
Facile characterization of aptamer kinetic and equilibrium binding properties using surface plasmon resonance
The AdoCbl-riboswitch interaction investitaged by in-line probing and surface plasmon resonance spectroscopoy (SPR)
Assessing RNA interactions with proteins by DRaCALA.Digital Access ScienceDirect 2014 - DigitalBee Ling Tan, Mohd Esa Norhaizan.Contents:
1. Introduction and Background
2. Rice demands: A Brief Description
3 Production of Rice By-products
4. Phytonutrients and Antioxidant Properties of Rice By-products
5. Potential Health Benefits of Rice By-products
6. Application in Food Products
7. Summary and Future Prospects
Conclusion.Digital Access Springer 2020 - DigitalTakuji Sasaki, Motoyuki Ashikari, editors.Summary: This book presents the latest advances in rice genomics, genetics and breeding, with a special focus on their importance for rice biology and how they are breathing new life into traditional genetics. Rice is the main staple food for more than half of the world's population. Accordingly, sustainable rice production is a crucial issue, particularly in Asia and Africa, where the population continues to grow at an alarming rate. The book's respective chapters offer new and timely perspectives on the synergistic effects of genomics and genetics in novel rice breeding approaches, which can help address the urgent issue of providing enough food for a global population that is expected to reach 9 billion by 2050.
Contents:
Intro; Preface; Contents;
Chapter 1: Genome Sequences of Oryza Species; 1.1 Introductory Overview of Rice Genome Sequencing; 1.2 Rice Genome Sequencing Projects and the Release of the IRGSP Reference Genome; 1.3 Genome Annotations and the Release of the Revised Genome Assembly, IRGSP-1.0; 1.4 De Novo Assembly of the indica Genome via NGS; 1.5 O. sativa Genome Resequencing Project; 1.6 Domestication History of O. sativa and Contribution of Genomic Studies; 1.7 Sequencing of O. glaberrima, African Cultivated Rice; 1.8 Wild Oryza Species. 1.9 The International Collaborative for Wild Oryza Species Genome Sequencing1.10 Distantly Related Wild Oryza Species; 1.11 Sequencing of O. punctata (BB) Genome; 1.12 Sequencing of O. officinalis (CC) Genome; 1.13 Sequencing of O. brachyantha, the Smallest Oryza Genome; 1.14 Perspectives; References;
Chapter 2: Small RNAs in Rice: Molecular Species and Their Functions; 2.1 Introduction; 2.2 Protein Components of Small RNA Pathways in Rice; 2.3 miRNA Gene Annotations in Rice; 2.4 Small RNAs and Abiotic Stress Responses in Rice; 2.5 Small RNAs and Immune Response in Rice. 2.5.1 Small RNAs in Rice-Bacterium Interactions2.5.2 Small RNAs Involved in Rice Immunity Against Blast Fungus; 2.5.3 Small RNAs in Rice-Virus Interactions; 2.5.4 Application of miRNA-Based Strategies to Produce Disease-Resistant Rice; 2.6 Rice Small RNAs and Crop Production; 2.7 Conclusion; References;
Chapter 3: Composition and Structure of Rice Centromeres and Telomeres; 3.1 Introduction; 3.2 Rice Centromere; 3.2.1 Genetically and Physically Mapped Centromere; 3.2.2 Composition and Structure of Centromere; 3.2.3 Functional Domains of Centromere; 3.2.4 Centromere Evolution. 3.3 Rice Telomere3.3.1 Composition and Organization of Telomere Sequences; 3.3.2 Sequence Variants of Telomere Satellite Repeat; 3.3.3 Variation of Telomere Length; 3.3.4 Subtelomere; 3.4 Conclusions; References;
Chapter 4: Rice Organelle Genomics: Approaches to Genetic Engineering and Breeding; 4.1 Mitochondrial Genomics in Rice; 4.1.1 Rice Mitochondrial Genome Sequencing; 4.1.2 Gene Contents and Genes Associated with Cytoplasmic Male Sterility; 4.1.3 Mitochondrial DNA Fragments in the Nuclear Genome; 4.2 Chloroplast Genomics in Rice. 4.2.1 Use of Rice Chloroplast Genomes for Comparative Genomics4.2.2 Perspectives on Rice Chloroplast Genome Engineering; References;
Chapter 5: Genetic and Epigenetic Regulation of Meiotic Fate Decision and Gametophyte Specification in Rice; 5.1 Introduction; 5.2 Sexual Organogenesis; 5.3 Germline Initiation and Meiotic Cell Fate Decision; 5.4 Meiosis-Specific Chromosomal Behavior; 5.5 Synaptonemal Complex Components; 5.6 Meiotic Recombination; 5.7 Epigenetics in Meiotic DSB Initiation; 5.8 Cell-Cell Communication in Meiosis and Postmeiosis; 5.9 Tapetal PCD. - DigitalTodd E. Rasmussen and Nigel R.M. Tai.Summary: For more than 40 years, Rich's Vascular Trauma has been surgeons' #1 reference for the diagnosis and treatment of vascular injury in both civilian and military settings across the globe. Published in association with the Society for Vascular Surgery (SVS),the fully updated 4th Edition reflects recent changes in vascular injury patterns, wounds, and trauma care, drawing from current research and a wide variety of peer-reviewed publications to keep you up to date with the latest evidence-based management strategies and techniques. Written and edited by vascular surgeons who are also trauma specialists--civilian and military experts who have proficiency in both open-surgical and endovascular techniques--this must-have reference offers a global perspective on every aspect of the broad spectrum of vascular trauma.Digital Access
- DigitalPaul D. Losty, Alan W. Flake, Risto J. Rintala, John M. Hutson, Naomi Iwai, editors.Digital Access Springer 2018
- DigitalSean P. Gaine, Robert Naeije, Andrew John Peacock, editors.Summary: "This comprehensive book describes the structure, function and imaging of the normal right heart both at rest and under the stresses of high altitude and exercise. It continues with a detailed examination of the pathophysiology and pathobiology of right heart dysfunction, both in experimental models and human disease, including congenital heart disease. Right heart dysfunction caused by pulmonary hypertension is discussed in particular detail. The Right Heart brings together a distinguished group of contributors to discuss the advances in the topic that have occurred over the last few years and provides a concise and up-to-date resource for clinicians by compiling this comprehensive state-of-the-art text on the subject, the Editors have created an indispensable reference for future work by those interested in the cardiopulmonary circuit. This book will appeal to respiratory physicians, cardiologists and intensivists, all of whom will share the Editors' belief that the right heart is fundamental to integrated cardiopulmonary performance."Digital Access Springer 2014
- DigitalSean P. Gaine, Robert Naeije, Andrew J. Peacock, editors.Summary: This heavily revised second edition of this critical book details the structure, function and imaging of the normal right heart both at rest and under the stresses of high altitude and exercise. Extensively revised chapters cover the pathophysiology and pathobiology of right heart dysfunction, both in experimental models and human disease, including congenital heart disease and pulmonary hypertension. The Right Heart provides a concise up-to-date guide on the latest advances in our understanding of role of the right heart in the cardiopulmonary circuit and is an indispensable up-to-date resource for clinicians interested in this topic.
Contents:
Part 1: Physiology, Pathology and Pathobiology
Function of the Right Ventricle
Right ventricular pathobiology
Experimental models of right heart dysfunction
Left-right ventricular interactions
Part 2: Imaging the Right Heart
Chapter 5: MRI of the normal and abnormal right ventricle at rest
Right ventricular structure and function during exercise
Echocardiography of the normal and abnormal Right Heart
Part 3: Causes of right heart dysfunction
Volume overload and the right heart
The right heart in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
Left heart failure and its effects on the right heart
Cor Pulmonale
High altitude and the right ventricle
The right ventricle in congenital heart disease
The right heart and acute pulmonary embolism
Right ventricular cardiomyopathies
Part 3: Treatment of right heart dysfunction
Right heart reverse remodelling during treatment for pulmonary hypertension
Acute right heart failure in the intensive care unit
Cardiac and lung transplantation and the right heart
Arrhythmias in Right Heart Failure due to pulmonary hypertension
Atrial septostomy and Potts Procedure
Part 4: Future perspectives
Treating the right ventricle directly in pulmonary hypertension. - DigitalSilviu Ionel Dumitrescu, Ion C. Ţintoiu, Malcolm John Underwood, editors.Summary: This book reviews the management of right heart diseases, incorporating etiology, physiopathology, prevention, diagnosis and treatment. The frequency of this pathology has increased in recent years, while techniques for its treatment have evolved. This book therefore represents a complete, detailed and updated presentation of this pathology, reviewing the expanded treatment options while considering the management of patients in detail. Right Heart Pathology: From Mechanism to Management provides a comprehensive insight into right heart pathology, current diagnostic methods, treatments and postsurgical management. Written by experienced cardiologists and cardiovascular surgeons who have addressed significant issues in this topic area, it represents the essential reference in this specialty.Digital Access Springer 2018
- Digitalvolume editors, E. Beghi, G. Logroscino.Contents:
The basic structure of a randomized clinical trial / Beghi, E
Peculiarities of neurological disorders and study designs / Beghi, E., Pupillo, E. Giussani, G.
Current issues in randomized clinical trials of neurodegenerative disorders at enrollment and reporting : diagnosis, recruitment, representativeness of patients, ethnicity, and quality of reporting / Logroscino, G., Capozzo, R., Tortelli, R., Marin, B.
How to distinguish between statistically significant results and clinically relevant results / Bennett, D.A.
Modeling and prediction in neurological disorders : the biostatistical perspective / Copetti, M. Fontana, A., Pellegrini, F.
Composite scores and other outcome measures in stroke trial / Pistoia, F., Sacco, S., Ornello, R., Degan, D., Tiseo, C., Carolei, A.
Age, comorbidity, frailty in observational and analytic studies of neurological diseases / Novy, J., Sander, J.W.
Disease course, outcome measures, and prognostic predictors in epilepsy : opportunities for improving outcome of drug trials / Schmidt, D.
Assessing functional decline in neurological diseases clinical trials : duration of follow-up : the case of multiple sclerosis / Martinelli Boneschi, F., Comi, G.
Biomarkers in randomized clinical trials : magnetic resonance imaging / Whitwell, J.L.
Biomarkers in randomized clinical trials : positron emission tomography and nuclear medicine techniques / Singhal, T., Stern, E
Cerebrospinal fluid biomarkers for target engagement and efficacy in clinical trials for Alzheimer's and Parkinson's diseases / Parnetti, L., Eusebi, P., Lleó, A
Pharmacogenetics in neurodegenerative diseases: implications for clinical trials / Tortelli, R., Seripa, D., Panza, F., Solfrizzi, V., Logroscino, G.
Randomized trials in developing countries : different priorities and study design? / Marin, B., Agbota, G.C., Preux, P.-M., Boumédiène, F.
The right therapy for neurological disorders : from randomized trials to clinical practice : patients versus investigator expectations and needs / Bruijn, L.I., Kolb, S.
General overview, conclusions, and future directions / Beghi, E., Logroscino, G.Digital Access Karger 2016 - DigitalDeborah Wallace, Rodrick Wallace.Summary: "This book discusses the socioeconomic effects of right-to-work (RTW) laws on state populations. RTW laws forbid requiring union membership even at union-represented worksites. The core of the 22 long-term RTW states was the Confederacy, cultural descendants of rigidly hierarchical agrarian feudal England. RTW laws buttress hierarchy and power imbalance which unions minimize at the worksite and by encouraging higher educational attainment, social mobility, and individual empowerment through group validation. Contrary to claims of RTW proponents, RTW and non-RTW states do not differ significantly in unemployment rates. RTW states have higher poverty rates, lower median household incomes, and lower educational attainment on average and median than non-RTW states. RTW states on average and median have lower life expectancy, higher obesity prevalence, and higher rates of all-cause mortality, early mortality from chronic conditions, child mortality, and risk behaviors than non-RTW states. The higher mortality rates result in startlingly higher annual numbers of years of life lost before age 75. Stroke mortality at age 55-64 in RTW states results in nearly 10,000 years annually lost in excess of what it would be if the mortality rate were that of non-RTW states. A review of respected publications describes the physiological mechanisms and epidemiology of accelerated aging due to socioeconomic stress. Unions challenge hierarchy directly at work-sites and indirectly through encouraging college education, social mobility, and community and political engagement. How startling that feudal hierarchy lives in 21st century America, shaping vast differences between states in macro- and micro-economics, educational attainment, innovation, life expectancy, obesity prevalence, chronic disease mortality, infant and child mortality, risk behaviors, and other public health markers! Readers will gain insight about the coming clash between feudal individualism and adaptive collectivism, and, in the last chapter, on ways to win the clash by 'missionary' work for collectivism."-- Back cover.
Contents:
The post-world war II America and the high point of union participation
What unions do for workers
Social and economic measures nationally and by RTW status
Social economic differences: RTW and non-RTW states
Measures of death
Early mortality from Ischemic heart disease (Coronary Heart Disease)
Premature unspecified stroke mortality
Obesity and diabetes
American child mortality, low-weight births
Taking risks
Resilience
RTW laws and public health.Digital Access Springer 2018 - DigitalNorbert F. Voelkel, Dietmar Schranz, editors.Summary: The Right Ventricle in Health and Disease provides a comprehensive and up-to-date database and collection of the available information which describes the structure and function of the normal right ventricle. The right ventricular performance and function reserve has now finally moved to the center of the stage as clinicians recognize that the drugs presently used to treat patients with severe pulmonary hypertension do not necessarily improve the performance of the right ventricle and because the survival depends on the right ventricular function that treatment strategies need to be developed to primarily protect the right ventricle from failing. In-depth chapters discuss right heart function and failure in patients with congenital heart diseases, review modern imaging techniques used to describe right ventricular form and function in patients with right heart failure (including cardiac MRI and PET scanning), describe ventricular interdependence: the left ventricle in pulmonary hypertension and discuss the concept of the sick lung circulation and its contribution to right heart failure. Treatment strategies of chronic right heart failure including drugs and mechanical devices are also discussed.
Contents:
Introduction
Section I: The Normal Right Ventricle
1. Normal development and morphology of the right ventricle: clinical relevance
2. Physiology of the Right Ventricle
3. The Neonatal Transition of the Right Ventricle
4. Advanced imaging of the right ventricle
Section II: Congenital abnormalities
5. Sub-pulmonary Right Ventricle in Congenital Heart Disease
6. The systemic Right Ventricle in Biventricular and Univentricular Circulation
7. Right Ventricle in structural and functional Left Ventricular Failure in Children
8. Missing a Sub-pulmonary Ventricle: The Fontan Circulation
Section III: Acute Right Heart Failure
9. Acute Right Ventricular Failure
Section IV: Chronic Right Ventricular Failure
10. Echocardiography of Chronic Right Heart Failure
11. Hemodynamic evaluation and exercise testing in chronic right ventricular failure
12. Cardiac MRI and PET scanning in right ventricular failure
13. The pathobiology of chronic right ventricular failure
14. The sick lung circulation and the failing right ventricle
15. Exercise induced right heart disease in athletes
16. Arrhythmogenic right ventricular cardiomyopathy (ARVC)
17. The Right Ventricle in Left Heart Failure
18. The Right Ventricle in Chronic Lung Diseases
19. Treatment of Chronic Right Heart Failure
20. Atrial septostomy
21. Right Ventricular Assist Devices
22. Animal models of chronic right ventricular stress and failure
Epilogue
Index.Digital Access Springer 2015 - PrintRichard Harris.Summary: American taxpayers spend $30 billion annually funding biomedical research. By some estimates, half of the results from these studies can't be replicated elsewhere -- the science is simply wrong. Often, research institutes and academia emphasize publishing results over getting the right answers, incentivizing poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence. How are those with breast cancer helped when the cell on which 900 papers are based turns out not to be a breast cancer cell at all? How effective could a new treatment for ALS be when it failed to cure even the mice it was initially tested on? Science journalist Richard F. Harris reveals these urgent issues with anecdotes, personal stories, and interviews with the nation's top biomedical researchers.
Contents:
Begley's bombshell
It's hard even on the good days
A bucket of cold water
Misled by mice
Trusting the untrustworthy
Jumping to conclusions
Show your work
A broken culture
The challenge of precision medicine
Inventing a discipline. - DigitalLawrence D. Longo ; foreword by John R.G. Challis.Summary: During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of fetal breathing movements, cyclic electroencephalographic activity, and analysis of electronic monitoring of fetal heart rate variability and its significance. Included in this book are reminisces of several dozen individuals who played a vital role in these developments. Overall, this survey considers a number of aspects of the development of the science of fetal and neonatal physiology, and its role in the greatly improved care of pregnant women and their newborn infants.
Contents:
A Scientific Genealogy: The Development of Fetal-Neonatal Research
Oxford and the Development of Physiology, with Notes on the Nuffield Institute
Geoffrey S. Dawes: A Life in Science
Dawes and Fetal Asphyxia: The Primate Colony in Puerto Rico
Dawes, the Pulmonary Vasculature and his Foetal and Neonatal Physiology
Embryology and Early Developmental Physiology
Some Aspects of the Physiology of the Placenta
Governmental Support of Research in Fetal and Newborn Physiology
Fetal-Neonatal Growth and Metabolism
Epigenetics and the Fetal Origins of Adult Heath and Disease
Related Developments in Fetal and Neonatal Endocrinology
Further Developments in Fetal and Neonatal Physiology
Some Clinical Aspects of Developmental Physiology
Bioethical Issues in Research on the Fetus and Newborn Infant
Textbooks, Monographs and other Volumes on Fetal and Newborn Physiology
Dawes and Fetal Breathing in the 1970s, and Fetal Heart Rate Analysis in the 1980s and early 1990s
Dawes Contributions to Symposia and a Summing Up
Dawes as a Mentor: Reminisces of Former Graduate Students, Postdoctoral Fellows, and Associates
Early Years of the Society for Gynecologic Investigation, the Fetal and Neonatal.Digital Access Springer 2013 - DigitalIain L.C. Chapple, Panos N. Papapanou, editors.
- Digitaledited by Sudha Seshadri and Stéphanie Debette.Summary: This text, by leading stroke researchers from Europe and North America, describes environmental and genetic risk factors for cerebrovascular disease. The section on genetics is exceptionally detailed and contemporaneous.
Contents:
Epidemiology of stroke : incidence and prevalence, description of types and subtypes and their relative frequency, definition of risk factors / E. Touzé + Y Bejot
Introduction to genetic risk factors for cerebrovascular disease / Bradford B. Worrall
Monogenic forms of stroke and cerebrovascular disease / A. Bersano
Heritability of stroke / A. Pedersen, A. C. Jern
Genetic determinants of ischemic stroke discovered through GWAS / S. Bevan & H. Markus
Genetic risk factors of intracerebral haemorrhage / G. Falcone & J. Rosand
Relevance in stroke of genes associated with cardiovascular disease and risk factors / M. Dichgans, R. Malik
Genetics of stroke associated with cervical artery dissections / S. Debette
Genetics of cerebral venous thrombosis / T. Marjot, P. Sharma
Genetic risk factors for brain MRI markers of cerebrovascular disease / G. Chauhan, S. Debette
Overview of environmental risk factors for stroke / Didier Leys
Hypertension : the major risk factor for stroke / Jennifer L. Dearborn, R. Gottesman
Dyslipidemia and risk of stroke / Sabrina Schilling, S. Debette
Metabolic risk factors : DM, obesity, metabolic syndrome / E. Camargo, L.J. Launer
Lifestyle factors and risk of stroke : smoking, alcohol, diet, physical activity, sleep / C. Satizabal
Risk factors specific to young adults / J. Putaala & T Tatlisumak
Sex-specific risk factors for stroke in women / S. Wise, C. Bushnell
Migraine and risk of stroke and cerebrovascular disease / A. Pezzini
Ethnic, racial and geographic variations in stroke risk and risk factors / H. Manosalvo, T. Jeerakathil
Intermediate markers : carotid atherosclerosis / David Della Morte, T. Rundek
MRI-based markers of cerebrovascular disease and the risk of stroke / S. Lorenzano, R. Rost
Circulating biomarkers for stroke / A. Pikula
Secular trends in stroke risk and risk factors for stroke / R. Carandang.Digital Access Oxford [2016] - DigitalYorimasa Ogata, editor.Summary: In this book, leading experts from around the world present the latest knowledge on the risk factors for peri-implant diseases and also examine the prevalence, etiology, and treatment strategy. Reports have suggested that a variety of risk factors, including poor oral hygiene, a history of periodontitis, diabetes, smoking, lack of keratinized mucosa, and implant surface topography, are associated with these diseases. Periodontally compromised patients who do not adhere completely to the supportive periodontal therapy have been found to present a higher implant failure rate, and several studies have shown that periodontal pathogens can translocate from periodontally involved teeth to the peri-implant sulci in partially dentate patients, highlighting the importance of periodontal treatment of the residual dentition prior to placement of dental implants. Recently a new concept was proposed as intraindividual variation exists in core microbiota in peri-implantitis and periodontitis. In elucidating the strength of association of peri-implant diseases with all of the risk factors identified to date, the book will be of interest to practitioners and other professionals in the field.
Contents:
Intro
Acknowledgments
Contents
Prevalence and Etiology for Peri-implant Diseases
Introduction
Prevalence of Peri-implant Mucositis and Peri-implantitis
Risk Factors/Indicators for Peri-implant Diseases
Poor Oral Hygiene/History of Periodontitis/Lack of Compliance with Regular Maintenance Therapy
Smoking
Diabetes Mellitus
Materials and Surface Characteristics of Implant Components [29-32]
Design of Implant-Supported Prostheses
Keratinized Mucosa
Excess Cement
Genetic Factors
Occlusal Overload
Pathogenesis of Peri-implant Diseases Structure and Composition of Periodontium and Peri-implant Tissue
Conclusion
References
Polymicrobial Peri-Implant Infection
Polymicrobial Infection and the Human Oral Cavity as a Space for Microbial Colonization
Bacteriological History of Periodontitis
Bacteriological History of Peri-Implant Infection
An Example of Investigating Bacterial Interaction at Peri-Implantitis Sites
Future Perspectives of Polymicrobial Peri-Implant Infection
References
Microbiological Factors of Peri-Implantitis: Methodologies for Biofilm Analysis
Section 1: Detection Methods Conventional Methods
Microscopy
Culture-Dependent Methods
Molecular Methods
Close-Ended Methods
PCR
Real Time-PCR (Quantitative PCR-qPCR)
Nested PCR
Multiplex PCR
Reverse Transcriptase PCR (RT-PCR)
Hybridization Approaches
The Checkerboard DNA-DNA Hybridization
Fluorescent In-situ Hybridizations (FISH)
Open-Ended Methods (Microbiome Strategies)
Targeted Microbiome Strategies
16S rRNA Gene Sequencing
Internal Transcribed Spacer (ITS) Sequencing
Technologies Used for 16S rRNA Gene Surveys in Peri-Implantitis Sanger Sequencing (Chain Terminating Sequencing)
Pyrosequencing
Illumina
Section 2: Functional Methods
Shotgun Metagenomics
Metatranscriptomics
Metaproteomics
Metabolomics
Conclusion
References
Microbiological Factors of Peri-Implantitis: Characteristics and Significance
Introduction
Healthy Implants vs Healthy Natural Teeth
Peri-Implant Mucositis vs Gingivitis
Periodontitis vs Peri-Implantitis
Disease Progression in Dental Implants
Microbiological Factors Related to Dental Implant Structure
Peri-Implant Sulcus Implant Abutment Connection and Interface
Dental Implant Surface
Summary
References
Association of Periodontitis and Biologic Implant Complications
Introduction
Associations Between Periodontitis and Peri-Implant Disease
Indirect Assessments: Implant Survival, Implant Success, and Marginal Bone Loss
Direct Assessment: History of Periodontitis and Peri-Implantitis
How Does Periodontitis Increase Risk of Biological Implant Complication?
Periodontitis and Peri-Implantitis: Common Microflora?
Periodontitis and Peri-Implantitis: Host Inflammatory DrivenDigital Access Springer 2020 - DigitalWalter Merkle, editor.Contents:
Why do we wrong, although we want to do right?- Current view of German Authorities
Human behavior in process management
Successful strategies to detect and avoid failures
Risk management in aviation
Risk management in medicine ? principles
Risk management in the US medicine
Systemic coaching of staff as risk management tool
CIRS (Critical Incident Reporting System)
OTAS (Observational Teamwork Assessment for Surgery)
FMEA (Failure Mode and Effects Analysis)
TTO (Team Time Out)
Peer-Review.- CRM (Crew Ressource Management).- Law aspects-Germany
Law aspects
Europe
Law Aspects
USA
Insurances problems
Implementation of risk management in hospitals
Economic aspects of risk management
ISO in medical risk management.Digital Access Springer 2016 - Digitaleditors in chief Michael Powers, Keith Rix ; editors, Keith Rix, Dr Laurence Mynors-Wallis, Dr Ciarán Craven.Summary: Rix's Expert Psychiatric Evidence is a resource manual and guide for psychiatrists who provide expert testimony. It covers the entire expert psychiatric witness journey, from training and negotiation of instructions, through medicolegal assessment, report preparation, experts' meetings and joint statements, and conferences with counsel, to giving evidence in court along with advice on keeping up to date. Introductory chapters include essential information on the law of expert evidence and the different procedures in the criminal, civil, family and coroners' courts. It now includes in depth information on all eight jurisdictions of the British Isles. It is richly illustrated with reported and unreported cases including many important ones from the previous ten years, particularly relating to vulnerable witnesses and defendants. The book is supplemented by a library of online letters, forms, a new format report template and other documents which can be downloaded and adapted by readers for their own use.Digital Access Cambridge 2021
- DigitalLong-Cheng Li, editor.Summary: This book offers an essential guide to RNA activation (RNAa), an emerging and fascinating new field. RNAa is a small RNA-guided and Argonaute-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs (dsRNAs) induce target gene expression at the transcriptional level. It occurs primarily in the nucleus and can be mediated by artificially designed short duplex RNAs that target regulatory sequences (e.g., promoters, genes' 3' termini and enhancers) and naturally occurring small RNAs (e.g., miRNAs and C. elegans 22G-RNAs). With contributions from internationally respected RNA experts, this book provides comprehensive coverage of different RNAa mechanisms and a timely update on recent advances in RNAa research, with a focus on developing RNAa-based therapeutics. Special chapters are also devoted to the topics of gene activation induced by antisense oligonucleotides and the CRISPR system. As the first book to cover RNAa, it will be of interest to a wide audience, from scientists in academia and the pharmaceutical industry to clinicians who wish to further explore the biology of RNAa and related phenomena, so as to harness their full potential for use in biotechnology and drug development.
Contents:
1. Small RNA-guided transcriptional gene activation (RNAa) in mammalian cells
2. Enhancing neurogenesis and counteracting neuropathogenic gene haploinsufficiencies by RNA gene activation
3. Target-recognition mechanism and specificity of RNA
4. Promoter-targeting small activating RNAs alter nucleosome positioning
5. Endogenous miRNAa: miRNA-mediated gene upregulation
6. miRNA-mediated RNA activation in mammalian cells
7. RNAa induced by TATA box-targeting microRNAs
8. miRNA-mediated RNAa by targeting enhancers
9. Specific increase of protein levels by enhancing translation using antisense oligonucleotides targeting upstream open frames
10. Repurposing CRISPR system for transcriptional activation
11. RNA-mediated gene activation: identifying a candidate RNA for preclinical development
12. Treatment of pancreatic cancer by aptamer conjugated C/EBPα-saRNA
13. Treatment of liver cancer by C/EBPA saRNA
14. Enhancing angiogeneis in mice by VEGF-targeting small activating RNAs
15. Suppression of prostate cancer metastasis by DPYSL3-targeted saRNA
16. Development of therapeutic dsP21-322 for cancer treatment
Index.Digital Access Springer 2017 - DigitalGuiliang Tang, Sachin Teotia, Xiaoqing Tang, Deepali Singh, editors.Summary: This book offers a unique and comprehensive overview of key RNA-based technologies, as well as their development and applications for the functional genomics of plant coding and non-coding genes. It focuses on the latest as well as classical RNA-based techniques used for studies on small RNAs, long non-coding RNAs and protein-coding genes. These techniques chiefly focus on target mimics (TMs) and short tandem target mimics (STTMs) for small RNAs, and artificial microRNAs (amiRNAs), RNA interference (RNAi) and CRISPR/Cas for genes. Furthermore, the book discusses the latest trends in the field and various modifications of the above-mentioned approaches, and explores how these RNA-based technologies have been developed, applied and validated as essential technologies in plant functional genomics. RNA-based technologies, their mechanisms of action, their advantages and disadvantages, and insights into the further development and applications of these technologies in plants are discussed. These techniques will enable the users to functionally characterize genes and small RNAs through silencing, overexpression and editing. Gathering contributions by globally respected experts, the book will appeal to students, teachers and scientists in academia and industry who are interested in horticulture, genetics, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture & genetic engineering, and functional genomics.
Contents:
Artificial Small RNAs for Functional Genomics in Plants
Use of mRNA-interactome capture for generating novel insights into plant RNA biology
Improving nutrient value of crops: Applications of RNAi in targeting plant metabolic pathways
Utilizing RNA-based approaches to understand plant-insect interactions. - Digitaledited by Ernesto Picardi.Contents:
Free energy minimization to predict RNA secondary structures and computational RNA design / Alexander Churkin, Lina Weinbrand, and Danny Barash
RNA secondary structure prediction from multi-aligned sequences / Michiaki Hamada
Simple protocol for the inference of RNA global pairwise alignments / Eugenio Mattei, Manuela Helmer-Citterich, and Fabrizio Ferrè
De novo secondary structure motif discovery using RNA profile / Federico Zambelli and Giulio Pavesi
Drawing and editing the secondary structure(s) of RNA / Yann Ponty and Fabrice Leclerc
Modeling and predicting RNA three-dimensional structures / Jérôme Waldispühl and Vladimir Reinharz
Fast prediction of RNA-RNA interaction using heuristic algorithm / Soheila Montaseri
Quality control of RNA-Seq experiments / Xing Li ... [and 3 others]
Accurate mapping of RNA-Seq data / Kin Fai Au
Quantifying entire transcriptomes by aligned RNA-Seq data / Raffaele A. Calogero and Francesca Zolezzi
Transcriptome assembly and alternative splicing analysis / Paola Bonizzoni ... [and 5 others]
Detection of post-transcriptional RNA editing events / Ernesto Picardi ... [and 3 others]
Prediction of miRNA targets / Anastasis Oulas ... [and 6 others]
Using deep sequencing data for identification of editing sites in mature miRNAs / Shahar Alon and Eli Eisenberg
NGS-trex : an automatic analysis workflow for RNA-seq data / Ilenia Boria ... [and 3 others]
e-DNA meta-barcoding : from NGS raw data to taxonomic profiling / Fosso Bruno, Marzano Marinella, and Monica Santamaria
Deciphering metatranscriptomic data / Evguenia Kopylova ... [and 6 others]
RIP-seq data analysis to determine RNA-protein associations / Federico Zambelli and Giulio Pavesi
ViennaRNA eeb services / Andreas R. Gruber, Stephan H. Bernhart, and Ronny Lorenz
Exploring the RNA editing potential of RNA-Seq data by ExpEdit / Mattia D'Antonio ... [and 4 others]
Guideline for the annotation of UTR regulatory elements in the UTRsite collection / Matteo Giulietti ... [and 3 others]
Rfam : annotating families of non-coding RNA sequences / Jennifer Daub ... [and 3 others]
ASPicDB : a database web tool for alternative splicing analysis / Mattia D'Antonio ... [and 5 others]
Analysis of alternative splicing events in custom gene datasets by AStalavista / Sylvain Foissac and Michael Sammeth
Computational design of artificial RNA molecules for gene regulation / Alessandro Laganà ... [and 6 others].Digital Access Springer 2015 - Printsymposium organizers and proceedings editors, Terri Grodzicker, David Stewart and Bruce Stillman.Summary: Summary: Order and Disorder in Brains and Behavior. "Topics addressed at the 2019 Symposium included RNA-based structures; RNA modifications; nuclear localization of RNA;quality control and editing; RNA and gene regulation; cotranscriptional splicing; intron-exon boundaries;alternative polyadenylation; transposon control; small noncoding RNAs; long noncoding RNAs; RNA anddevelopment; membraneless organelles; phase separation; RNA-based diseases; and novel RNA functions."--Foreword.
Contents:
Dorcas Cummings Lecture: Dorcas Cummings Lecture.Digital Access Cold Spring Harbor Lab Press 2020 - Digitaledited by Christina Waldsich.Contents:
Predicting RNA Structure: Advances and Limitations
Cis-Acting 5' Hammerhead Optimization for In Vitro Transcription of Highly Structured RNAs
RNA Structural Analysis by Enzymatic Digestion
A Mutate-and-Map Protocol for Inferring Base Pairs in Structured RNA
Mapping RNA Structure In Vitro Using Nucleobase-Specific Probes
Massively Parallel RNA Chemical Mapping with a Reduced Bias MAP-Seq Protocol
Probing RNA Folding by Hydroxyl Radical Footprinting
Monitoring Global Structural Changes and Specific Metal Binding Sites in RNA by In-Line Probing and Tb(III) Cleavage
Chemical Probing of RNA in Living Cells
A Chemogenetic Approach to Study the Structural Basis of Protein-Facilitated RNA Folding
Applying UV Crosslinking to Study RNA-Protein Interactions in Multicomponent Ribonucleoprotein Complexes
The Kinetics of Ribozyme Cleavage: A Tool to Analyze RNA Folding as a Function of Catalysis
RNA Catalytic Activity as a Probe of Chaperone-Mediated RNA Folding
Evaluation of RNA Chaperone Activity In Vivo and In Vitro Using Misfolded Group I Ribozymes
RNA Conformational Changes Analyzed by Comparative Gel Electrophoresis
Detecting RNA Tertiary Folding by Sedimentation Velocity Analytical Ultracentrifugation
RNA Folding Dynamics Using Laser Assisted Single-Molecule Refolding
RNA Refolding Studied by Light-Coupled NMR Spectroscopy
Exploring RNA Oligomerization and Ligand Binding by Fluorescence Correlation Spectroscopy and Small Angle X-Ray Scattering. - Digitaledited by Zdravka Medarova.Contents:
Imaging functional nucleic acid delivery to skin / Roger L. Kaspar ... [et al.]
In vivo magnetic resonance imaging of small interfering RNA nanodelivery to pancreatic islets / Ping Wang and Anna Moore
Magnetic resonance spectroscopy of siRNA-based cancer therapy / Marie-France Penet ... [et al.]
Targeted delivery with imaging assessment of siRNA expressing nanocassettes into cancer / Wei Chen and Lily Yang
Analyses of tumor burden in vivo and metastasis ex vivo using luciferase-expressing cancer cells in an orthotopic mouse model of neuroblastoma / Frances L. Byrne, Joshua A. McCarroll, and Maria Kavallaris
Indium-labeling of siRNA for small animal SPECT imaging / Steven Jones and Olivia Merkel
Imaging of electrotransferred siRNA / Muriel Golzio and Justin Teissié
Whole-body scanning PCR, a tool for the visualization of the in vivo biodistribution pattern of endogenous and exogenous oligonucleotides in rodents / Julien A. Boos and Iwan Beuvink
siRNA nanoparticles for ultra-long gene silencing in vivo / Seung Koo Lee and Ching-Hsuan Tung
Sensing miRNA : signal amplification by cognate RISC for intracellular detection of miRNA in live cells / Amol Kavishwar and Zdravka Medarova
Molecular beacon-based microRNA imaging during neurogenesis / Jonghwan Lee and Soonhag Kim
Hypoxia-responsive copolymer for siRNA delivery / Federico Perche ... [et al.]
Controlling RNA expression in cancer using iron oxide nanoparticles detectable by MRI and in vivo optical imaging / Zdravka Medarova, Mustafa Balcioglu, and Mehmet V. Yigit
Microvesicles : isolation, characterization for in vitro and in vivo procedures / Karmele Valencia and Fernando Lecanda
Positive bioluminescence imaging of microRNA expression in small animal models using an engineered genetic-switch expression system, RILES / Patrick Baril and Chantal Pichon
MicroRNA imaging in combination with diagnostic ultrasound and bubble liposomes for microRNA delivery / Yoko Endo-Takahashi ... [et al.].Digital Access Springer 2016 - Digitaledited by Mouldy Sioud.Contents:
RNA interference : mechanisms, technical challenges, and therapeutic opportunities / Mouldy Sioud
Nanostructured RNAs for RNA interference / Yuko Nakashima [and others]
One long oligonucleotide or two short oligonucleotides based shRNA construction and expression / Xue-jun Wang and Sheng-qi Wang
PLGA microspheres encapsulating siRNA / Giuseppe De Rosa and Giuseppina Salzano
Magnetic nanoparticle and magnetic field assisted siRNA delivery in vitro / Olga Mykhaylyk [and others]
Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation / Mouldy Sioud
Delivery of siRNAs to cancer cells via bacteria / Omar Ahmed, Andrea Krühn, and Hermann Lage
Microwell array-mediated delivery of lipoplexes containing nucleic acids for enhanced therapeutic efficacy / Yun Wu, Daniel Gallego-Perez, and L. James Lee
Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy / Karin Zins [and others]
Targeted in vivo delivery of siRNA and an endosome- releasing agent to hepatocytes / Magdolna G. Sebestyén [and others]
Cell-internalization SELEX : method for identifying cell- internalizing RNA aptamers for delivering siRNAs to target cells / William H. Thiel [and others]
Strategies for siRNA navigation to desired cells / Mouldy Sioud
Use of guanidinopropyl-modified siRNAs to silence gene expression / Maximilian C.R. Buff [and others]
Therapy of respiratory viral infections with intranasal siRNAs / Sailen Barik and Patrick Lu
Engineering therapeutic cancer vaccines that activate antitumor immunity / Per Ole Iversen and Mouldy Sioud
Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses / Mouldy Sioud, Anne Mobergslien, and Stein Sæbøe-Larssen
Targeting bcr-abl transcripts with siRNAs in an imatinib- resistant chronic myeloid leukemia patient : challenges and future directions / Michael Koldehoff
Facile method for interfering with off-target silencing mediated by the sense strand / Anne Mobergslien and Mouldy Sioud
Overcoming the challenges of siRNA activation of innate immunity : design better therapeutic siRNAs / Mouldy Sioud
Gene silencing in vitro and in vivo using intronic microRNAs / Jia Han Deng [and others]
In silico identification of novel endo-siRNAs / Andrew Schuster [and others]
Computer-assisted annotation of small RNA transcriptomes / Nicole Ortogero [and others]
miR-CATCH : microRNA capture affinity technology / Sebastian Vencken [and others]
Roles of MicroRNAs in cancers and development / Shigeru Takasaki
Targeting microRNAs to withstand cancer metastasis / Valentina Profumo [and others]
Urinary microRNAs as a new class of noninvasive biomarkers in oncology, nephrology, and cardiology / Hana Mlcochova [and others]
Magnetic bead-based isolation of exosomes / Morten P. Oksvold, Axl Neurauter, and Ketil W. Pedersen
Modified 2'-ribose small RNAs function as toll-like receptor-7/8 antagonists / Mouldy Sioud.Digital Access Springer 2015 - Digitaledited by M. Lucrecia Alvarez, Mahtab Nourbakhsh.Contents:
Part I Structural RNA mapping
Full-length characterization of transcribed genomic region
Rapid mapping of RNA 3 and 5 ends
Single nucleotide mapping of RNA 5 and 3 ends
Analysis of RNA secondary structure
Tertiary structure mapping of the Pri-miRNA miR-17-92
In situ hybridization detection of miRNA using LNA [trademark] oligonucleotides
Quantification of miRNAs by a simple and specific qPCR method
RNA isolation for small RNA next-generation sequencing from acellular biofluids
Sequencing small RNA : introduction and data analysis fundamentals
Measuring expression levels of small regulatory RNA molecules from body fluids and formalin-fixed, paraffin-embedded samples
MicroRNA profiling in plasma or serum using quantitative RT-PCR
MicroRNA profiling of exosomes isolated from biofluids and conditioned media
Isolation of urinary exosomes for RNA biomarker discovery using a simple, fast, and highly scalable method
Part II Functional RNA mapping
Identification of actively translated mRNAs
Mapping of internal ribosome entry sites (IRES)
Mapping of protein binding RNA elements
Purification of RNA-binding proteins
De novo approach to classify protein-coding and noncoding transcripts based on sequence composition
Computational methods to predict long noncoding RNA functions based on co-expression network
MicroRNA biogenesis : dicing assay
Faster experimental validation of microRNA targets using cold fusion cloning and a dual firefly-Renilla luciferase reporter assay
Experimental validation of predicted mammalian microRNAs of mirtron origin
A guide for miRNA target prediction and analysis using web-based applications
Tapping microRNA regulation networks through integrated analysis of microRNA-mRNA high-throughput profiles
miRWalk database for miRNA-target interactions
A schematic workflow for collecting information about the interaction between copy number variants and microRNAs using existing resources
SYBR green and TaqMan quantitative PCR arrays : expression profile of genes relevant to a pathway or a disease state
Comprehensive meta-analysis of microRNA expression using a robust rank aggregation approach.Digital Access Springer 2014 - Digitaledited by Chuan He.Contents:
Methodology for the high-throughput identification and characterization of tRNA variants that are substrates for a tRNA decay pathway
Nucleoside analysis by hydrophilic interaction liquid chromatography coupled with mass spectrometry
A platform for discovery and quantification of modified ribonucleosides in RNA: application to stress-induced reprogramming of tRNA modifications
Recogniion of specified RNA modifications by the innate immune system
Kinetic analysis of tRNA methyltransferases
Preparation of human nuclear RNA m6A methyltransferases and demethylases and biochemical characterization of their catalytic activity
Transcriptome-wide mapping of N6-methyladenosine by m6A-Seq
Probing RNA modification status at single-nucleotide resolution in total RNA
High-resolution mapping of N6-methyladenosine in transcriptome and genome using a photo-crosslinking-assisted strategy
Pseudouridine in mRNA: incorporation, detection, and recoding
Pseudo-Seq: genome-wide detection of pseudouridine modifications in RNA
Pseudouridine chemical labeling and profiling
Experimental approaches for target profiling of RNA cytosine methyltranferases
RNA 5-methylcytosine analysis by bisulfite sequencing
Biochemical and transcriptome-wide identification of A-to-I RNA editing sites by ICE-Seq
Radical SAM-mediated methylation of ribosomal RNA.Digital Access ScienceDirect 2015 - Digital/PrintGene W. Yeo, editor.Contents:
Experimental and computational considerations in the study of RNA binding protein-RNA interactions
Genome-wide approaches for RNA structure probing
Tethered function assays as tools to elucidate the molecular roles of RNA binding proteins
Single molecule approaches in RNA-protein interactions
RNA dynamics in the control of circadian rhythm
Roles of RNA binding proteins and post-transcriptional regulation in driving male germ cell development in the mouse
Regulation of stem cell self-renewal and oncogenesis by RNA binding proteins
Controlling the editor: the many roles of RNA binding proteins in regulating A-to-I RNA editing
Mutations in splicing factors and cancer
Regulation of tissue-specific alternative splicing: C. elegans as a model system
RNA Granules and Diseases
A Case Study of Stress Granules in ALS and FTLD
Post-translational modifications and RNA-binding proteins.Digital Access Springer 2016 - Digitaledited by Frank J. Schmidt.Contents:
Identifying RNA recombination events and non-covalent RNA-RNA interactions with the molecular colony technique / Helena V. Chetverina and Alexander B. Chetverin
RNA-directed recombination of RNA in vitro / Niles Lehman, Nilesh Vaidya, and Jessica A.M. Yeates
RNA-RNA SELEX / B. Cho
Identification of antisense RNA stem-loops that inhibit RNA-protein interactions using a bacterial reporter system / Kazuo Harada
Transactivation of large ribozymes / Matthew B. Martin, Thomas L. Leeper, and Frank J. Schmidt
Native purification and labeling of RNA for single molecule fluorescence studies / Arlie J. Rinaldi, Krishna C. Suddala, and Nils G. Walter
Single molecule studies of RNA-RNA interactions / Dongmei Yu, Peiwu Qin, and Peter V. Cornish
Modification interference analysis of the ribosome / Simpson Joseph
Assessing intermolecular RNA:RNA interactions within a ribonucleoprotein complex using heavy metal cleavage mapping / Keith T. Gagnon and E. Stuart Maxwell
Electrophoretic mobility shift assays : analysis of tRNA binding to the T box riboswitch antiterminator RNA / R. Anupam, S. Zhou, and J.V. Hines
Fluorescence anisotropy : analysis of tRNA binding to the T box riboswitch antiterminator RNA / S. Zhou, R. Anupam, and J.V. Hines
Electrophoretic mobility shift assay of RNA-RNA complexes / Geunu Bak [and three others]
Structural studies of a double-stranded RNA from trypanosome RNA editing by small-angle X-ray scattering / Angela Criswell and Blaine H.M. Mooers
Fusion RNAs in crystallographic studies of double-stranded RNA from trypanosome RNA editing / Blaine H.M. Mooers.Digital Access Springer 2015 - Digitaledited by Luc Ponchon.Contents:
Method to predict the 3D structure of an RNA scaffold / Xiaojun Xu and Shi-Jie Chen
Post-crystallization improvement of RNA crystal diffraction quality / Jinwei Zhang and Adrian R. Ferré-D'Amaré
Expression and purification of RNA-protein complexes in Escherichia coli / Margueritte El Khouri and others
Production of homogeneous recombinant RNA using a tRNA scaffold and hammerhead ribozymes / Frank H.T. Nelissen, Hans A. Heus, and Sybren S. Wijmenga
In vivo production of small recombinant RNAs embedded in a 5S rRNA-derived protective scaffold / Victor G. Stepanov and George E. Fox
Detection of RNA-protein interactions using tethered RNA affinity capture / Hidekazu Iioka and Ian G. Macara
Universal method for labeling native RNA in live bacterial cells / Irina Smolina and Natalia Broude
Live cell imaging using riboswitch-spinach tRNA fusions as metabolite-sensing fluorescent biosensors / Colleen A. Kellenberger, Zachary F. Hallberg, and Ming C. Hammond
RNA scaffold : designed to co-localize enzymes / ZJU_China Team (iGEM 2012) and Ming Chen
Artificial ligase ribozymes isolated by a "Design and Selection" strategy / Shigeyoshi Matsumura and Yoshiya Ikawa
Engineering aptazyme switches for conditional gene expression in mammalian cells utilizing an in vivo screening approach / Charlotte Rehm, Benedikt Klauser, and Jörg S. Hartig
Aptazyme-based riboswitches and logic gates in mammalian cells / Yoko Nomura and Yohei Yokobayashi
Design and characterization of topological small RNAs / Jack Hassall and others
Folding RNA-protein complex into designed nanostructures / Tomonori Shibata and others
Simple method for constructing RNA triangle, square, pentagon by tuning interior RNA 3WJ angle from 60° to 90° or 108° / Emil F. Khisamutdinov and others
RNA-mediated CdS-based nanostructures / Vinit Kumar and Anil Kumar
Effective method for specific gene silencing in Escherichia coli using artificial small RNA / Geunu Bak and others.Digital Access Springer 2015 - Digitaledited by Jan Gorodkin, Walter L. Ruzzo.Summary: The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results. Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.
Contents:
Concepts and Introduction to RNA Bioinformatics
The Principles of RNA Structure Architecture
The Determination of RNA Folding Nearest Neighbor Parameters
Energy Directed RNA Structure Prediction
Introduction to Stochastic Context Free Grammars
An Introduction to RNA Databases
Energy-based RNA Consensus Secondary Structure Prediction in Multiple Sequence Alignments
SCFGs in RNA Secondary Structure Prediction: A Hands-on Approach
Annotating Functional RNAs in Genomes using Infernal
Class-specific Prediction of ncRNAs
Abstract Shape Analysis of RNA
Introduction to RNA Secondary Structure Comparison
RNA Structural Alignments, Part I: Sankoff Based Approaches for Structural Alignments
RNA Structural Alignments, Part II: Non-Sankoff Approaches for Structural Alignments
De novo Discovery of Structured ncRNA Motifs in Genomic Sequences.,
Phylogeny and Evolution of RNA Structure
The Art of Editing RNA Structural Alignments
Automated Modeling of RNA 3D Structure
Computational Prediction of RNA-RNA Interactions
Computational Prediction of microRNA Genes
MicroRNA Target Finding by Comparative Genomics
Bioinformatics of siRNA Design
RNA-protein Interactions: An Overview.Digital Access Springer 2014 - DigitalEhren Myers.Summary: Quickly access the must-have information you need to deliver safe and effective health care in both hospital and home settings. Add in NCLEX tips and you have the perfect pocket-sized resource for class, clinical, exam prep, and practice. -- From publisher's description.
Contents:
Procedures
Assess
Life span
Emerg trauma
Meds/IV/Fluids
Labs/ECG
Diseases & patient ed
Tools/Index.Digital Access R2Library 2018Limited to 1 simultaneous user - DigitalCarol J. Huston.Summary: The Road to Leadership presents nine valuable leadership lessons from award-winning author and international nurse leader Carol Huston. This small, full-color book packs big wisdom from a leader who learned her lessons the hard wayand now leads others to their own paths as confident, successful leaders. From finding a mentor to learning the art of communication, this engaging book will help you break free of professional limits and define your own effective leadership skills. -- Provided by publisher.
Contents:
Find a mentor and positive role models to share your journey
Be self-aware and authentic
Be able to laugh at yourself and leave your ego at home in a jar
Be visionary, take risks, and ask for permission only when necessary
Maintain personal power : keep gas in the tank and money in the bank
Choose your battles carefully
Perfect the "art" of communication
Appreciate and empower followers
Set priorities and enjoy the journey.Digital Access AccessAPN 2018 - DigitalCarol J. Huston.Contents:
Chapter 1: The Leader's Role in Creating and Sustaining Positive Work Cultures
Chapter 2: Establish a Culture of Mutual Respect and Civility
Chapter 3: Maintain Appropriate Boundaries
Chapter 4: Avoid Micromanaging
Chapter 5: Deal With Problems When They Occur
Chapter 6: Build Effective Teams
Chapter 7: Reduce Workplace Stress
Chapter 8: Show Appreciation and Reward Desired Behavior Appropriately
Chapter 9: Be an Authentic Leader
Chapter 10: Be Passionate and Purposeful in Looking to the FutureReferences
IndexDigital Access R2Library 2020 - Digitalprepared for the AAMC by: Arthur L. Coleman, Katherine E. Lipper, Teresa E. Taylor, Scott R. Palmer, Education Counsel LLCSummary: Roadmap to Diversity and Educational Excellence provides guidance on legal and policy underpinnings for developing and evaluating sustainable, mission-driven, diversity-related policies and practices. This second edition includes new guidance based on the U.S. Supreme Court's 2013 decision in Fisher v. University of Texas. More than just a legal update, this publication provides additional insights into relevant facets of law, policy, and research, to reflect the current challenges that medical schools face. A new chapter helps schools explore the necessity of their race-conscious policies and practices, and a new appendix focuses on operational questions to consider when pursuing race-neutral strategies.
Contents:
"Rules of the Road": key points your school needs to know about access and diversity policies
Staying the course: clarity and consistency on key policy concepts
Agreeing on the destination: why student diversity may matter at your medical school
Navigating your route: ensuring that the consideration of race is necessary
Reaching the destination: a management strategy and plan for enhancing diversity at your medical school.Digital Access R2Library 2014 - Digital[edited by] Vinay Kumar, Abul K. Abbas, Jon C. Aster.Contents:
The cell as a unit of health and disease
Cell injury, cell death, and adaptations
Inflammation and repair
Hemodynamic disorders, thromboembolic disease, and shock
Genetic disorders
Diseases of the immune system
Neoplasia
Infectious diseases
Environmental and nutritional diseases
Diseases of infancy and childhood
Blood vessels
The heart
Diseases of white blood cells, lymph nodes, spleen, and thymus
Red blood cell and bleeding disorders
The lung
Head and neck
The gastrointestinal tract
Liver and gallbladder
The pancreas
The kidney
The lower urinary tract and male genital system
The female genital tract
The breast
The endocrine system
The skin
Bones, joints, and soft tissue tumors
Peripheral nerves and skeletal muscles
The central nervous system
The eye.Digital Access ClinicalKey 2021 - Digital[edited by] Vinay Kumar, Abul K. Abbas, Jon C. Aster, Andrea T. Deyrup, Abhijit Das.Summary: Readable, well-illustrated, and concise, Robbins and Kumar’s Basic Pathology, 11th Edition, offers today’s busy students a rich understanding of all essential pathology concepts from trusted names in the field. This updated edition thoroughly covers key pathologic processes and the time-honored tools of gross and microscopic analysis, while also retaining a strong emphasis on clinicopathologic correlations and the impact of molecular pathology on the practice of medicine. Outstanding artwork and schematic drawings, as well as a robust eBook experience with extensive additional features, make complex concepts easier to learn and retain.
Contents:
Cell Injury, Cell Death, and Adaptations
Inflammation and Repair
Hemodynamic Disorders, Thromboembolism, and Shock
Genetic and Pediatric Diseases
Diseases of the Immune System
Neoplasia
Environmental and Nutritional Diseases
Blood Vessels
Heart
Hematopoietic and Lymphoid Systems
Lung
Kidney
Oral Cavity and Gastrointestinal Tract
Liver and Gallbladder
Pancreas
Male Genital System and Lower Urinary Tract
Female Genital System and Breast
Endocrine System
Bones, Joints, and Soft Tissue Tumors
Peripheral Nerves and Muscles
Central Nervous System and Eye
Skin.Digital Access ClinicalKey 2023 - DigitalEdward C. Klatt.Summary: "Designed to complement Robbins and Cotran Pathologic Basis of Disease, 10th Edition and Robbins Basic Pathology, 10th Edition, the full-color Robbins and Cotran Atlas of Pathology offers more than 1,800 outstanding illustrations that vividly depict the most common diseases covered in pathology courses and USMLE exams. Covering all major topic areas in organ system pathology and incorporating the latest understanding of pathophysiology and molecular medicine, it is a quick visual reference or review for students and professionals alike"--Publisher's description.
Contents:
Blood vessels
The heart
Hematopathology
Red blood cell disorders
The lungs
Head and neck
The gastrointestinal tract
The liver and biliary tract
The pancreas
The kidneys
The lower urinary tract
The male genital tract
The female genital tract
The breasts
The endocrine system
The skin
Bones, joints, and soft tissues
Peripheral nerve and skeletal muscle
The central nervous system
The eyes.Digital Access ClinicalKey 2021 - Print[edited by] Vinay Kumar, Abul K. Abbas, Jon C. Aster ; with illustrations by James A. Perkins.
- DigitalEdward C. Klatt, Vinay Kumar.Contents:
The lung
Head and neck
Gastrointestinal tract
Liver and biliary tract
Pancreas
Kidney
The lower urinary tract and male genital system
Female genital tract
The breast
The endocrine system
The skin
Bones, joints, and soft-tissue tumors
Peripheral nerve and skeletal muscle
Central nervous system
The eye
Final review and assessment.Digital Access ProQuest Ebook Central 2015Limited to 3 simultaneous users - Digital/Print[edited by] Vinay Kumar, Abul K. Abbas, Jon C. Aster ; artist, James A. Perkins.Contents:
The cell as a unit of health and disease / Richard. N. Mitchell
Cell injury, cell death, and adaptations
Inflammation and repair
Hemodynamic disorders, thromboembolism, and shock
Diseases of the immune system
Neoplasia
Genetic and pediatric diseases / Anirban Maitra
Environmental and nutritional diseases
General pathology of infectious diseases / Alexander J. McAdam, Karen M. Frank
Blood vessels / Richard N. Mitchell
Heart / Richard N. Mitchell
Hematopoietic and lymphoid systems
Lung / Aliya Noor Husain
Kidney and its collecting system / Anthony Chang, Zoltan Laszik
Oral cavity and gastrointestinal tract / Jerrold R. Turner, Mark W. Lingen
Liver and gallbladder / Neil D. Theise
Pancreas / Anirban Maitra
Male genital system and lower urinary tract / Jonathan Epstein, Tamara L. Lotan
Female genital system and breast / Lora Hedrick Ellenson, Susan C. Lester
Endocrine system / Anirban Maitra
Bones, joints, and soft tissue tumors / Andrew Horvai
Peripheral nerves and muscles / Peter Pytel
Central nervous system / Matthew P. Frosch
Skin / Alexander J.F. Lazar. - PrintVinay Kumar, Abul K. Abbas, Jon C. Aster, Andrea T. Deyrup.Print
- DigitalLaura Weiss Roberts, editor.Summary: This book was written to assist early- and middle-career physicians, clinicians, and scientists in understanding the unique mission of academic medicine and to help them build creative, effective and inspiring careers in academic health organizations.Digital Access Springer 2020
- Digitaleditor-in-chief, James R. Roberts ; senior editor, Catherine B. Custalow ; illustration editor, Todd W. Thomsen.Contents:
Section I: Vital signs and patient monitoring techniques. Vital sign measurement
Devices for assessing oxygenation and ventilation
Section II: Respiratory procedures. Basic airway management and decision making
Tracheal intubation
Pharmacologic adjuncts to intubation
Cricothyrotomy and percutaneous translaryngeal ventilation
Tracheostomy care
Mechanical ventilation
Thoracentesis
Tube thoracostomy
Section III: Cardiac procedures. Techniques for supraventricular tachycardias
Defibrillation and cardioversion
Assessment of implantable devices
Basic electrocardiograph techniques
Emergency cardiac pacing
Pericardiocentesis
CPR and artificial perfusion during cardiac arrest
Resuscitative thoracotomy
Section IV: Vascular techniques and volume support. Pediatric vascular access and blood sampling techniques
Arterial puncture and cannulation
Peripheral intravenous access
Central venous catheterization and central venous pressure monitoring
Venous cutdown
Indwelling vascular devices: emergency access and management
Intraosseous infusion
Alternative methods of drug administration
Autotransfusion
Transfusion therapy: blood and blood products
Section V: Anesthetic and analgesic techniques. Local and topical anesthesia
Regional anesthesia of the head and neck
Regional anesthesia of the thorax and extremities
Intravenous regional anesthesia
Systemic analgesia and sedation for procedures
Section VI: Soft tissue procedures. Principles of wound management
Methods of wound closure
Foreign body removal
Incision and drainage
Burn care procedures
Section VII: gastrointestinal procedures. Esophageal foreign bodies
Nasogastric and feeding tube placement
Balloon tamponade of gastroesophageal varices
Decontamination of the poisoned patient
Peritoneal procedures
Abdominal hernia reduction
Anorectal procedures
Section VIII: Musculoskeletal procedures. Prehospital immobilzation
Management of amputations
Extensor and flexor tendon injuries in the hand, wrist, and foot
Management of common dislocations
Splinting techniques
Podiatric procedures
Treatment of bursitis, tendinitis, and trigger points
Arthrocentesis
Compartment syndrome evaluation
Section IX: Genitourinary obstetric, and gynecologic procedures. Urologic procedures
Emergency childbirth
Gynecologic procedures
Examination of the sexual assault victim
Section X: Neurologic procedures. Management of increased intracranial pressure and intracranial shunts
Spinal puncture and cerebrospinal fluid examination
Special neurologic tests and procedures
Section XI: Ophthalmologic, otolaryngologic, and dental procedures. Ophthalmologic procedures
Ototlaryngologic procedures
Emergency dental procedures
Section XII: Special procedures. Procedures pertaining to hypothermia and hyperthermia
Ultrasound
Bedside laboratory and microbiologic procedures
Standard precautions and infectious exposure management
Physical and chemical restraint
Noncardiac implantable devices
Radiation in pregnancy and clinical issues of radiocontrast agents
Procedures in the setting of anticoagulation
Appendix. Commonly used formulas and calculations.Digital Access ClinicalKey 2019 - DigitalShancheng Ren, Senthil Nathan, Nicola Pavan, Di Gu, Ashwin Sridhar, Riccardo Autorino, editors.Summary: This book comprehensively covers the techniques available for robot- assisted prostatectomy. Chapters feature detailed descriptions of how to successfully perform a variety of relevant techniques including the reconstruction of continence mechanisms and the use of the transperitoneal RALP anterior approach. Potential complications, preoperative and postoperative management strategies are also discussed, enabling the reader to develop a thorough understanding of how to apply a range of relevant methodologies into their day-to-day clinical practice and avoid commonly encountered pitfalls. Robot-Assisted Radical Prostatectomy: Advanced Surgical Techniques provides a practically applicable resource for all practicing and trainee urologists seeking a detailed overview of the latest advances in robot-assisted surgical procedures and current management strategies applicable to prostatectomy.
- DigitalJohn W. Davis, editor.Contents:
Minimally invasive access to the prostate
The concept of surgical space creation
Surgeon's Notebook: Beyond the Learning Curve: The Original Handouts from the American Urological Association Post-graduate Courses 2013-2015
The Dorsal Vein Complex
Achieving Hemostasis and Proper Set-up for Apical Division
The Simple Bladder Neck
Bladder Neck
Anatomic Variants, Prior TUR, Locally Advanced Tumors
Neurovascular Bundle Preservation: Anatomic and Technical Considerations
Partial Neurovascular Bundle Sparing during Robot-Assisted Radical Prostatectomy
Neurovascular Structure-adjacent Frozen-section Examination (NeuroSAFE) in robot-assisted radical prostatectomy
Neurovascular Bundle
Wide Excision
Apex
The Crossroads of Functional Recovery and Oncologic Control
Post-Resection: Hemostasis, Checking for Rectal Injury, Anastomotic Leaks
Denonvilliers Fascia
Anatomy, Surgical Planes, Use in Reconstruction
Vesico-urethral Anastomosis
Putting it Back Together
Pelvic Lymph Node Dissection
Open Benchmarks with Lymphoscintigraphy
Pelvic Lymph Node Dissection
Robotic Surgery Efficiency and Space-Creation Techniques to Achieve an Extended Template
Innovation and Orientation Challenges
Posterior "Retzius Sparing" Technique
Getting Out
Closure, Prevention and Management of Hernias
Robot-Assisted Radical Prostatectomy Extraperitoneal and Transperitoneal Techniques
Perioperative Medical Evaluation of the Patient undergoing RARP
Patient Positioning and Safety in Steep Trendelenburg
Safety checklist for training and assessment in robot assisted prostate surgery
Immediate Post-Operative Care Following Robot Assisted Radical Prostatectomy
Penile Rehabilitation: Recovering Erectile Function following Prostate Cancer Treatment
Structured Reporting of RARP Complications
Are We Making Measurable Progress?
Quality of Life Evaluation: What is Published and Practical for Routine Use
Positive Surgical Margins: How to Self-Evaluate and Improve
High Risk Pathology: State-of-the-Art Post-Operative Radiation Recommendations and Integration of Novel Genomic Risk Biomarkers
Long-term Oncologic Outcomes
Personalized versus Generic Patient Handouts
Tools to Improve Patient Knowledge on Treatment Options and Peri-operative Care
Active Surveillance and Patient Support Intervention
A Return to Key Surgical Technique: Neurovascular Bundle Sparing with Antegrade Technique.Digital Access Springer 2016 - DigitalHoward Ross, Sang W. Lee, Bradley J. Champagne, Alessio Pigazzi, David E. Rivadeneira, editors.Digital Access Springer 2015
- DigitalKarl A. LeBlanc, editor.Summary: This book provides a guide to procedures and techniques related to robotic hernia repair. Sections covering inguinal, incisional, and diaphragmatic hernias are included. Each section will cover the setup of the operating room and the management of adverse events specific to the hernia. The steps involved in performing an operation and key components to a successful repair are also covered The book aims to cover recent technology and updates related to robotic hernia repair. Robotic Assisted Hernia Repair is relevant to robotic hernia surgeons, fellows training in minimally invasive surgery, and general surgical residents. -- Provided by publisher.
Contents:
Part I: General topics: 1. Robotic technologies (past, present and future) / Brian S. Peters, Priscila R. Armijo, and Dmitry Oleynikov
2. Adoption of robotic technology in surgical practice / Ekatarina Elliott, John J. Hall, Erik B. Wilson, Shinil K. Shah, and Melissa M. Felinski
3. Enhanced recovery after hernia repair / Frederik Berrevoet
4. Prosthetic materials for robot-assisted hernia repair / Karl A. LeBlanc
5. Algorithm of open/laparoscopic/robotic repair / Archana Ramaswamy
6. Etiology and management of hernia-related chronic pain : implications of robotics / Ian T. MacQueen and David C. Chen. Part II: Inguinal hernia: 7. Operating room set up for robotic assisted inguinal hernia repair / Aldo Fafaj and Ajita Prabhu
8. Routine robotic inguinal hernia repair / Joseph Dux, Loic Tchokouani, Erica D. Kane, and Brian P. Jacob
9. Robotic repair of giant inguinal hernias / David S. Edelman
10. Pelvic hernias / Ricardo Zugaib Abdalla and Thiago Nogueira Costa
11. Adverse events of robotic transabdominal preperitoneal inguinal hernia repair / Matthew Sharbaugh, Liam Knott, and T. Paul Singh
12. Re-operation after robotic inguinal hernia repair / Jordan A. Bilezikian, Robert G. Johnson, and William W. Hope. Part III: Ventral and incisional hernia: 13. Botulinum toxin aided hernia repair / Talar Tejirian and Louise Yeung
14. Pneumoperitoneum aided hernia repair / Yohann Renard, Cheryne Hammoutene, and Jean-Pierre Palot
15. Operating room setup and intraoperative considerations for robotic ventral hernia repair / Jefferson Tyler Watson and Karl A. LeBlanc
16. Diastasis recti : robotic extended-view totally extraperitoneal (eTEP) access hernia repair technique / Igor Belyansky, Richard Lu, and Alex Addo
17. Robotic IPOM-plus repair / Eduardo Parra-Davila, Carlos Hartmann, and Juan Maldonado
18. Transabdominal preperitoneal (rTAPP) repair / Fahri Gokcal and Yusef Kudsi
19. Stapled closure for mid-line hernia repair / Thiago Nogueira Costa and Ricardo Zugaib Abdalla
20. Endoscopic component separation techniques / Jorge Daes
21. Robotic retro-rectus repairs / Flavio Malcher, Leandro Totti Cavazzola, and Igor Belyansky
22. Robotic transversus abdominus release / David Bernstein and Garth R. Jacobsen
23. Subxiphoid and suprapubic hernia repair / Karl A. LeBlanc
24. Lumbar hernia / Maamoun Harmouch and Karl A. LeBlanc
25. Robotic-assisted parastomal hernia repair : Sugarbaker repair (with and without component release) / Alex Addo, Richard Lu, Igor Belyansky, and Karl A. LeBlanc
26. Robotic ventral and incisional hernia repair : management of adverse events / Anthony M. Gonzalez and Rodolfo J. Oviedo
27. Incisional hernia in oncologic surgery / John M. Lyons III. Part IV: Diaphragmatic hernia: 28. Operating room set up in the repair of diaphragmatic hernia / Elizabeth Colsen
29. Robotic assisted Morgagni hernia repair / Francesco M. Bianco, Yevhen Pavelko, and Antonio Gangemi
30. Robotic paraesophageal hernia repair / Robert F. Cubas, Joslin N. Cheverie, and Santiago Horgan
31. Magnetic sphincter augmentation for management of gastroesophageal reflux disease / Mark G. Hausmann and Karl A. LeBlanc
32. Adverse events in robotic assisted hiatal hernia repair / Alexander C. Mertens and Ivo A. M. J. Broeders
33. Reoperation after robotic diaphragmatic hernia repair / Jordan A. Bilezikian, Robert G. Johnson, W. Borden Hooks III, and William W. Hope.Digital Access Springer 2019 - Digitaledited by Pedro Encarnação and Albert M. Cook.Contents:
1. Fundamentals of Robotic Assistive Technologies
2. Human-Robot Interaction for Rehabilitation Robots
3. Assistive Robotic Manipulators
4. Upper and Lower Limb Robotic Prostheses
5..Smart Wheelchairs for Assessment and Mobility
6. Exoskeletons as an Assistive Technology for Mobility and Manipulation
7. Robotic Systems for Augmentative Manipulation to Promote Cognitive Development, Play, and Education
8. Social Assistive Robots for Children with Complex Disabilities
9. Robots Supporting Care for Elderly People
10. Ethical and Social Implications of the Use of Robots in Rehabilitation Practice.Digital Access TandFonline 2017 - DigitalChangqing Gao, editor.Summary: Robotic Cardiac Surgery is a comprehensive guide to robotic/totally endoscopic cardiac surgery. The book is intended to provide in-depth information regarding the history of robotic surgical systems, their components and principles. It emphasizes patient selection, perioperative management, anesthesia considerations and management, operative techniques and management, postoperative care and results. Extensive, detailed photographs and illustrations of different kinds of robotic surgery are also included. It provides cardiac surgeons, cardiac anesthesiologists, and perfusionists with a comprehensive review of current robotic cardiac surgeries and related knowledge.
Contents:
Overview of Robotic Cardiac Surgery
Anesthesia for Robotic Cardiac Surgery
Intraoperative Transesophageal Echocardiography in Robotic Cardiac Surgery
Peripheral Cardiopulmonary Bypass Establishment for Robotic Cardiac Surgery
Robotic Surgery in Congenital Heart Diseases
Totally Robotic Myxoma Excision
Robotic Mitral Valve Surgery
Robotic Coronary Bypass Graft on Beating Heart
Hybrid Coronary Revascularization
Robotic Left Ventricular Epicardial Lead Implantation. - DigitalVincent Obias, editor.Summary: The initial chapters discuss the start of minimally invasive surgery and robotics. Subsequent chapters address starting up a robotics program and incorporating robotics into ones practice. The textbook next centers on specific robotic techniques or robotic management of certain disease processes. These chapters are written by experts in the fields and include multiple tables, illustrations, and videos describing the techniques where applicable. Each chapter also discusses the current literature. The final chapters focus on the future of robotics, cost of robotics, and include other possible future platforms and as well as the new FDA approved Xi and SP Intuitive surgical platforms. Robotic Colon and Rectal Surgery: Principles and Practice presents the first in-depth, cohesive and comprehensive approach to all aspects of robotic colorectal surgery.
Contents:
Introduction: The Evolution of Minimally Invasive Surgery- The Learning Curve of Robotic Assisted Laparoscopic Colorectal Surgery and How to Start Applying Robotic Technology in Colorectal Surgery
Training and Credentialing in Robotics
Robotic Right Hemicolectomy
Robotic Abdominoperineal Resection
Robotic Low Anterior Resection of Rectal Cancer
Robotic Total Colectomy
Robotic Assisted Transanal Microscopic Surgery
Surgical Immunofluorescence and Firefly Technology in Colon and Rectal Surgery
Surgery on Obese Patients
Robotics and Pelvic Floor
Inflammatory Bowel Disease
Ergonomics in Robotic Colorectal Surgery
Nerve Preservation in Robotic Rectal Surgery
Completed and Ongoing Trials in Robotic Colorectal Surgery
Robotic Costs
The Robotic-Assisted Treatment of Endometriosis: A Colorectal Surgical Perspective
Anesthesia in Robotic Colon and Rectal Surgery
Single-Incision Robotic Colon Resection (SIRC)
Reducing Conversions in Robotic Surgery
Current and Future Platforms for Robotic Colorectal Surgery
Closing Acknowledgements.Digital Access Springer 2017 - DigitalPeter Coyne, Jim Khan, editors.Summary: This book provides a concise overview of the robotic techniques applicable to colorectal surgery. Initially, it describes how to set-up an operating room from an ergonomics perspective. Detailed guidance is then provided on how to apply robotic platforms to the rectum, colon and abdominal wall. Emphasis is placed on describing the latest procedures and how to utilize them in a particular scenario. Instructional picture material and tips and tricks from world leading experts contain tips on how to successfully perform many of the techniques covered, enabling the reader to systematically develop a detailed knowledge of the methodology and how to potentially troubleshoot any issues that may arise. Robotic Colorectal Surgery: Complete Manual of Surgical Techniques describes how to apply the latest robotic techniques in everyday colorectal surgery practice, making it an indispensable resource for trainee and practicing surgeons.
Contents:
Introduction
Part 1: Basics
Robotic port positioning
Robotic docking
Dealing with clashes
Robotic ergonomics: Different systems CMR Versius robot system
Colorectal surgery with the senhance digital laparoscopic platform
Robotic surgery: Role of the surgical care practitioner
Part 2: Rectum
Robotic high anterior resection
Rectal surgery: Low anterior resection
Robotic low anterior resection using Da Vinci-Xi system: Addressing the ergonomics dilemma
Robotic APR
Robotic lateral pelvic lymph node dissection
Robotic Transanal Total Mesorectal Excision (taTME)
Transanal surgery and Single port robotic platform
Part 3: Colon
Robotic standard right hemicolectomy with intra-corporeal anastomosis
Robotic right hemicolectomy: Complete mesocolic excision and intracorporeal anastomosis
Robotic subtotal colectomy
Robotic splenic flexure mobilization
Part 4: Miscellaneous
Robotic surgery for perforated diverticulitis
Robotic urological surgery for colorectal surgeons
Robotic approach for ileal-pouch-anal-anastomosis
Parastomal and Perineal hernia repair. - DigitalSaid Abdallah, Al-Mamari, Hervé Quintens, editors.Summary: Robotic Donor Nephrectomy - A Practical Guide is a user friendly manual aimed to give both novice and mature urologists a clear and comprehensive description of robot-assisted laparoscopic donor nephrectomy through a step-by-step approach. Novel techniques such as the Laparo-Endoscopic Single-Site (LESS) surgery are examined and the editors also look at the well established multi-ports techniques using the da Vinci Surgical system. Robotic Donor Nephrectomy - A Practical Guide will help young urologists gain better understanding of the techniques of robotic-assisted surgery, and support older urologists in 'crossing the border' towards laparoscopic surgery, particularly for delicate procedures such as the donor nephrectomy.Digital Access Springer 2014
- Digital[edited by] David Goldenberg, Neerav Goyal ; Tess Marhofer, medical illustrator.Summary: Robotic Head and Neck Surgery: An Anatomical and Surgical Atlas is a splendidly illustrated anatomical guide on current and emerging procedures from David Goldenberg and Neerav Goyal. It fills a gap in available resources and offers surgical pearls from prominent head and neck surgeons who have pioneered and mastered robotic techniques. The atlas reflects expanding indications for head and neck robotics including midline glossectomy for obstructive sleep apnea, nasopharyngeal surgery, laryngectomy, transaxillary parathyroidectomy, facelift thyroidectomy, and robot-assisted neck dissection. Key features: Nine visually-rich chapters provide concise yet detailed procedural guidance including key landmarks, vascular and nervous structures, background, indications, surgical anatomy, step-by-step diagrams, and radiologic imaging; Exquisite anatomical illustrations by Tess Marhofer and stunning cadaveric dissections provide the ability to see detailed anatomy from the robot's perspective; Videos with cadaveric and live patient dissections provide additional endoscopic insights. -- Publisher.
Contents:
Oropharyngeal anatomy and radical tonsillectomy / Neerav Goyal, Frederick Yoo, and David Goldenberg
Base of tongue resection and hypopharyngeal anatomy / Aaron Baker, Neerav Goyal, and David Goldenberg
Parapharyngeal space anatomy and dissection / Daniel Clayburg and Umamaheswar Duvvuri
Anatomy of the trans-oral robotic retropharyngeal node dissection / Hetal H. Patel and Neerav Goyal
Nasopharyngeal anatomy and approaches to the nasopharynx / Irina Chaikhoutdinov and David Goldenberg
Robotic supraglottic anatomy and laryngectomy technique / Ryan Li and Jeremy J. Richmon
Robotic-assisted thyroidectomy and parathyroidectomy : transaxillary approach / Salah Eldin Mohamed, Nuha Al-Saleh, Daniah Bu Ali, and Emad Kandil
Surgical anatomy of robotic facelift thyroidectomy / Katrina Chaung, William S. Duke, and David J. Terris
Robotic-assisted neck dissection / Hung Kwon Beyon and Yoon Woo Koh.Digital Access - Digital[edited by] J. Scott Magnuson, Eric M. Genden, Ronald B. Kuppersmith.Contents:
The contemporary history of robotic technology / Jason I. Kass and Eric M. Genden
Training and education for robotic surgery / Julia A. Crawford and J. Scott Magnuson
The ethics of surgical innovation / Ronald B. Kuppersmith
Room set-up and instrumentation / Julia A. Crawford, Hilliary N. White, and J. Scott Magnuson
Robotic surgery for management of oropharyngeal malignancies / Mara C. Modest and Eric J. Moore
Robotic reconstruction of the oropharynx / Eric M. Genden
The prevention and management of complications in robotic surgery for malignancy / Julia A. Crawford, Hilliary N. White, and J. Scott Magnuson
Robotic surgery for the management of sleep apnea / Claudio A. Vicini, Filippo Montevecchi, Ahmed Yassin Bahgat, Mohamed Eesa, Ehsan Hendawy, Giuseppe Meccariello, and Julia A. Crawford
The prevention and management of complications of robotic sleep surgery / Filippo Montevecchi, Julia A. Crawford, Susan K. Sebastian, and Claudio A. Vicini
Robotic surgery of the larynx / Richard V. Smith
Robotic surgery of the hypopharynx / Brett A. Miles
Robotic surgery of the parapharyngeal space / Suren Krishnan
Transaxillary robotic thyroidectomy / Jandee Lee and Woong Youn Chung
Robotic neck dissection / Hyung Kwon Byeon and Yoon Woo Koh
Robotic surgery of the skull base / Michael E. Kupferman and Ehab Y. Hanna
The future of robotic surgery / Roger Smith.Digital Access Thieme MedOne Otolaryngology 2016 - DigitalOmar Yusef Kudsi, editor.Summary: This atlas demonstrates how to perform each available extraperitoneal hernia repair via a set of high-quality annotated images showing step-by-step guidance on how to perform the surgery. Robotic extraperitoneal hernia procedures are considered great teaching procedures especially with a dual teaching console. The book bridges the gap between traditional hernia and laparoscopic hernia texts by combining both approaches to create a book with a unique visual approach. Preoperative, intraoperative, and postoperative figures are integrated to highlight the importance of these step-by-step procedures, enhance skill and efficiency, and avoid surgical pitfalls. Detailed descriptive figures accompany step-by-step instructions and include specific anatomical annotations that describe the anatomy and layers of the abdominal wall during hernia procedures. Robotic Hernia Surgery provides a comprehensive, insightful and state-of-art review of this field, and serves as a valuable resource for surgeons, surgeons in training, and students with an interest in hernia and robotic hernia surgery.
Contents:
Robotic Transabdominal Preperitoneal Repair for Subxiphoid Hernia (TAPP)
Robotic Epigastric Hernia Repair: Totally Extraperitoneal (TEP)
Robotic Umbilical Hernia Repair: Totally Extraperitoneal (TEP)
Robotic Hybrid Ventral Hernia Repair: Totally Extraperitoneal (TEP)
Robotic Supra-pubic Hernia Repair Transabdominal Preperitoneal (TAPP)
Robotic Posterior Component Separation
Robotic Extended Totally Extraperitoneal (reTEP) Midline Ventral Hernia Repair
Robotic Subcostal Hernia Repair: Totally Extraperitoneal (TEP)
Hybrid Robotic Lateral Incisional Hernia Repair: Totally Extraperitoneal (TEP)
Robotic Totally Extraperitoneal (TEP) Flank Hernia Repair
Robotic Parastomal Hernia Repair
Robotic Lumbar Hernia Repair: Totally Extraperitoneal (TEP)
Robotic Iliac Hernia Repair: Totally Extraperitoneal (TEP)
Robotic Inguinoscrotal Hernia Repair: Transabdominal Preperitoneal (TAPP)
Robotic Direct Inguinal Hernia Repair: Transabdominal Preperitoneal (TAPP)
Robotic Anterior Component Separation. - DigitalGo Watanabe, editor.Contents:
1. Overview of robotic surgery
2. The de Vinci Surgical® systesm
3. Development of robotic systems
4. Robotic surgery in urology
5. Robotic gastrectomy for gastric cancer
6. Esophageal cancer surgery: robotic esophagectomy - 7. Lateral pelvic node dissection for advanced rectal cancer: current debates and use of the robotic approach
8. Cardiac surgery: overview
9. Robotically assisted totally endoscopic coronary artery bypass grafting
10. Robotic surgery for mitral valve disease
11. Robotic surgery in general thoracic surgery
12. Robot-assisted thyroidectomy. - DigitalFarid Gharagozloo, Vipul R. Patel, Pier Cristoforo Giulianotti, Robert Poston, Rainer Gruessner, Mark Meyer, editors.Summary: The first edition of Robotic Surgery was written only a decade after the introduction of robotic technology. It was the first comprehensive robotic surgery reference and represented the early pioneering look ahead to the future of surgery. Building upon its success, this successor edition serves as a complete multi-specialty sourcebook for robotic surgery. It seeks to explore an in-depth look into surgical robotics and remote technologies leading to the goal of achieving the benefits of traditional surgery with the least disruption to the normal functions of the human body. Written by experts in the field, chapters cover the fundamental principles of robotic surgery and provide clear instruction on their clinical application and long term results. Most notably, one chapter on "The Blueprint for the Establishment of a Successful Robotic Surgery Program: Lessons from Admiral Hymen R. Rickover and the Nuclear Navy" outlines the many valuable lessons from the transformative change which was brought about by the introduction of nuclear technology into the conventional navy with Safety as the singular goal of the change process. Robotics represents a monumental triumph of surgical technology. Undoubtedly, the safety of the patient will be the ultimate determinant of its success. The second edition of Robotic Surgery aims to erase the artificial boundaries of specialization based on regional anatomy and serves as a comprehensive multispecialty reference for all robot surgeons. It allows them to contemplate crossing boundaries which are historically defined by traditional open surgery.
Contents:
Robotic surgery: overview
Thoracic section
Esophageal and foregut section
Bariatric surgery section
General surgery section
Urology section
Gynecology section
Gyencology oncology section
Cardiovascular section
Colorectal section
Otolaryngology section. - DigitalGiuseppe Spinoglio, editor ; in collaboration with Alessandra Marano and Giampaolo Formisano ; forewords by Giorgio De Toma, Francesco Corcione.Summary: This book describes the current applications of the robotic system in general surgery, focusing on the technical aspects of the procedures most commonly performed by this means. It provides a comprehensive overview of the state of the art in robotic surgery and presents the most recently available evidence as documented in the literature. The opening chapters review robotic platforms, discuss the general advantages, limitations, and strategies of robotic surgery, and identify challenges and critical elements when setting up a robotic program. The full range of applications of the robotic system is then covered, encompassing thoracic, esophageal, gastric, hepatobiliopancreatic, splenic, colorectal, endocrine, and transplantation surgery. Detailed attention is also paid to innovative applications and future trends in the robotic platform, with inclusion of a special chapter on fluorescence imaging during robotic procedures. The book closes by considering aspects related to credentialing and privileging, such as mentoring, proctoring, and teaching modules for residents and fellows. Against the background of increasing acceptance of the robotic surgery system across the globe, this book will be invaluable for all general surgeons. There is no doubt that within general surgery the system will continue to flourish on account of its undoubted technical advantages, which minimize most of the intrinsic shortcomings of laparoscopy.
Contents:
Foreword
Preface
1 History of Robotic Surgery
2 Transaxillary Thyroidectomy and Parathyroidectomy
3 Zenker diverticulum treatment
4 Thoracic surgery
5 Esophagectomy for cancer
6 Anti-Reflux Procedures and Cardioesophagomyotomy
7 Gastrectomy for cancer
8 Robotic Subtotal Gastrectomy: a Modified Korean Technique
9 Hepatic resections
10 Biliary Tract Tumors (Resection and Reconstruction)
11 Pancreatic Surgery for Cancer
12 Right Colectomy for Cancer: Three-arm Technique
13 Right Colectomy with Complete Mesocolic Excision: Four-arm Technique
14 Left colectomy and segmental resections for cancer
15 Robotic surgery for complicated diverticulitis
16 Hybrid robotic technique for rectal cancer (low anterior resection and abdominal perineal resection)
17 Full robotic technique for rectal cancer
18 Single-SiteTM Surgery
19 ICG Fluorescence: current and future applications
20 Splenectomy and hemisplenectomy.-21 Transperitoneal Adrenalectomy.-22 Robotic assisted organ transplantation.Digital Access Springer 2015 - DigitalGongxian Wang, Yu Zeng, Xia Sheng, editors.Summary: Written in readable format and rich with clinical cases, this book systematically introduces surgical nursing during robotic surgery. The first part introduces the history of robotic surgery, operating room management, quality control of robotic surgical nursing, management of safety, infection, and anaesthesia. The second part introduces key points of nursing during robotic surgery in urology, general surgery, gynaecology, heart, chest and otorhinolaryngology. It will be a helpful reference for practitioners those in the process of implanting or about to implant robotic surgery.
Contents:
History of Robotic Surgery
Requirement of Robotic Operating Room
Basic Operating in a Robotic Operating Room
Management and Training of Robotic Surgery Team
Quality Control of Robotic Surgical Nursing
Management of Instruments in a Robotic Operating Room
Safety Management of Robotic Surgery
Infection Management of Robotic Surgery
Perioperative Patient Care
Emergency Management in Robotic Surgery
Performance Management in Robotic Surgery
Anaesthesia Management in Robotic Surgery
Care Cooperation during Urologic Robotic Surgeries
Care Cooperation during General Robotic Surgeries
Care Cooperation during Gynaecological Robotic Surgeries
Care Cooperation during Cardiac Robotic Surgeries
Care Cooperation during Robotic Thoracic Surgery
Care Cooperation with Robotic Surgery in Otorhinolaryngology. - DigitalSanchia S. Goonewardene, Raj Persad, David Albala, editors.Summary: This latest book in the Management of Urology Series provides insight into how to appropriately manage patients undergoing pelvic robotic urological surgery for renal cancer. Extensive guidance is provided on how to perform a range of procedures including the retroperitoneal renal approach along with information on how to utilize the latest robots effectively. Cases are also presented on how to best manage complications associated with partial nephrectomy. Each chapter also contains learning objectives to assist the reader in extrapolating the key information covered. Robotic Surgery for Renal Cancer is an up-to-date overview of the latest techniques utilized in this field along with potential management strategies for these patients, making it a critical resource for urologists, oncologists, and specialist nurses.
Contents:
Intro
Preface
Acknowledgements
Contents
About the Editors
Abbreviations
1 Suturing Techniques in Robot-Asssisted Partial Nephrectomy (RAPN)
1.1 Introduction
1.2 Classic Renorrhaphy
1.3 Single Versus Double Layer
1.4 Running Versus Interrupted Suture
1.5 Barbed Versus Nonbarbed Suture
1.6 Hemostatic Agents
1.7 Selective Suturing-Sutureless Technique
1.8 Conclusion
References
2 Resection Techniques Robotic-Assisted Partial Nephrectomy
References
3 Clamping Techniques for Partial Nephrectomy
3.1 Introduction
3.2 Warm-Ischemia Resection 3.3 Off-Clamp Resection
3.4 Early Unclamping
3.5 Superselective Clamping
3.6 Cold Ischemia
3.7 Reclamping
3.8 Summary
References
4 Robotic Retroperitoneal Partial Nephrectomy
4.1 Introduction
4.2 Patient Selection
4.3 Pre-operative Evaluation and Preparation
4.4 Patient Position
4.5 Obtaining Access
4.6 Robot Docking
4.7 Partial Nephrectomy: Techniques
4.8 Special Concerns
4.8.1 Breach of Peritoneum
4.8.2 Selective Artery Clamping
4.8.3 Parenchyma Around Tumour Lights Up with ICG
4.9 Literature Review 4.9.1 Operative Time and Warm Ischemia Time
4.9.2 Estimated Blood Loss and Length of Hospital Stay
4.9.3 Clavien-Dindo Minor (Grade 1 to 2) and Major (Grade 3 to 5) Complications
4.9.4 Decline in Estimated Glomerular Filtration Rate and Upstaging of Chronic Kidney Disease
4.9.5 Positive Surgical Margin and Overall Tumour Recurrence
4.9.6 Summary of Evidence
5 Robotic Partial Nephrectomy
5.1 Indications
5.2 Techniques
5.2.1 Approaches
5.2.2 Pedicle Management
5.2.3 Resection and Suture Techniques
5.2.4 Novel Technologies
5.3 Conclusions
References 6 Pushing the Boundaries in Robot-Assisted Partial Nephrectomy for Renal Cancer
6.1 Pre-operative Planning with 3D Models
6.2 Hilum Control
6.2.1 Off-Clamp Resection
6.2.2 Early Unclamping
6.2.3 Superselective Clamping = "zero Ischemia"
6.2.4 Cold Ischemia
6.3 Tumour Resection Strategy
6.4 Future Perspectives
6.4.1 3D Model Generation
6.4.2 Virtual Models and Augmented Reality
6.5 Conclusions
References
7 Perioperative Surgical Complications in Robotic Partial Nephrectomy
7.1 Introduction
7.2 Definition and Rates 7.3 Pre-operative Prevention of Complications
7.4 Intraoperative Complications
7.4.1 Intraoperative Adverse Events Leading to Bleeding
7.4.2 Intraoperative Tumor Violation (ITV)
7.4.3 Visceral Injuries
7.4.4 Thoracic Complications
7.5 Postoperative Complications
7.5.1 Postoperative Bleeding
7.5.2 Urinary Leak
7.5.3 Acute Kidney Injury
7.6 Conclusions
References
8 Renal Robotic Surgery for Lefties: Left-Handedness in Upper Tract Robotic Surgery
8.1 Introduction
8.2 Upper Tract Robotic Surgery
8.2.1 Instruments - DigitalErik P. Castle, Raj S. Pruthi, editors.Summary: Robotic Surgery of the Bladder is a dedicated resource to understanding and mastering the concepts and practical aspects of robotic bladder surgery. The volume provides an introduction to urologists interested in initiating robotic radical cystectomy by providing them background, concepts, steps, and tools and tricks to introduce robotic radical cystectomy into their clinical practice, all in a safe, stepwise, and organized manner. For the more experienced robotic surgeon, the text serves as a resource for more advanced applications and techniques. The volume is also accompanied by many still images and a DVD of video clips. Written by experts in the field, Robotic Surgery of the Bladder is a comprehensive resource that maintains the time-tested oncologic principles of bladder cancer surgery, while introducing the advantages that exist with robotic-assisted approaches.
Contents:
History of minimally invasive techniques for radical cystectomy with urinary diversion
Principles of bladder cancer surgery
Robot Assisted Cystectomy: Getting started prior experience, learning curve, and initial patient selection
Robotic Cystectomy: Room set-up, patient positioning, instrumentation, and anesthetic considerations
Preoperative preparation and care
Robot Assisted Radical Cystectomy - Male
Robotic assisted laparoscopic anterior pelvic exenteration for bladder cancer in the female
Variations in surgical approach partial cystectomy, vaginal-sparing, and prostate-sparing
Robot-Assisted Pelvic Lymphadenectomy
Extracorporeal urinary diversion
Robot Assisted Intracorporeal ileal conduit
Intracorporeal ileal neobladder
Peri-operative care the radical cystectomy pathway
Oncologic outcomes
Peri-operative outcomes and complications of robot assisted cystectomy
Surgical avoidance and management of operative complications
Cost of robotic assisted radical cystectomy
Questions and concerns of robotic approaches to bladder cancer surgery
Robot assisted surgery for benign disease of the bladder
Future directions in robotic surgery for bladder cancer. - DigitalGregory A. Grillone and Scharukh Jalisi.Summary: Robotic Surgery of the Head and Neck is the first comprehensive guide for otolaryngologists who wish to perform robotic head and neck surgery. Edited by leaders in the field, this book focuses on how improved access, visualization, and flexibility of the technology have greatly expanded the capabilities of the head and neck surgeon to treat diseases transorally or through small incisions in the skin. Starting with an overview of minimally invasive surgery in the head and neck, and moving to discussions of anatomic considerations for these procedures and the future applications of robotic surgery for otolaryngologists, Robotic Surgery of the Head and Neck explores the exciting progress of robotic technologies, bringing physicians closer to achieving the benefits of traditional surgery with the least amount of disruption to the patient.
- Digitaledited by Vipul R. Patel.Summary: The heavily revised third edition of this essential textbook provides a comprehensive practically applicable guide to robotic surgical techniques in urology. Extensively updated chapters cover general aspects of surgery such as aspects of operating room preparation and anesthesia. Instructions on how to use a variety of the latest techniques for procedures associated with the kidney, prostate, bladder and testicle are covered. Detailed information on how to improve outcomes, avoid potential complications and pitfalls is also provided. Instructive video clips assist the reader in being able to visualize how to enhance their methodologies further. Robotic Urologic Surgery is a detailed up-to-date resource that includes contributions from leading robotic urologic surgeons from around the world. It assists readers in refining their surgical technique and improving their patient care. Therefore, it is a critical resource for all practicing and trainee physicians involved in the care of these patients. .
Contents:
General aspects of Robotic Surgery
Robotic surgery evolution (2000-SP) and new robotic platforms
How to implement a successful multidisciplinary robotic program
Robotic training and certification
Complications in robotic surgery
Preparation of the operating room, back table, and surgical team
Role of the tableside assistant in robotic surgeries
Anesthesia in robotic surgeries. (our experience with TAP block)
Robotic surgery management in oncologic patients during pandemic and challenging scenarios
Prostate
Prostate cancer screening and trends in the last 15 years (TASK force paper)
Current Imaging exams to access prostate cancer
Current protocols and technologies in Prostate cancer biopsy
Prostate anatomy and concepts to improve RARP outcomes
Trocar placement and challenges during the peritoneal access
Intraoperative technologies
Current techniques to perform a RARP
RARP in a high volume center and step-by-step technique (Patels technique)
Single Port approach to radical prostatectomy
Retzius sparing technique
Extraperitoneal RARP
Lymphadenectomy in prostate cancer: technique and outcomes
Robotic-assisted Salvage Prostatectomy
Challenges during RARP
Functional and oncological outcomes following RARP
Managing complications during a RARP
How to maximize the penile rehabilitation following a RARP
Robotic approach to BPH disease
Kidney, adrenals, and ureter
Renal anatomy, physiology and its clinical relevance to nephrectomy
Training and challenges to perform robotic-assisted kidney surgeries
Robotic-assisted radical nephrectomy and nephroureterectomy
Robotic-assisted Partial nephrectomy
Challenges and robotic approach to nephrectomy with Vena Cava thrombus
Outcomes of robotic radical and partial nephrectomy
Single port approach to kidney surgery.-Current status of Robotic-assisted pyeloplasty in adults
The role of robotics for adrenal surgery
Robotic surgery techniques in ureteral reconstruction and implantation
Current application of robotic surgery in kidney transplants
Complications and management in robotic-assisted kidney surgeries
Bladder
Surgical anatomy and different aspects to optimize outcomes in robotic- assisted cystetomies
Step-by-step approach to robotic cystectomy and intracorporeal urinary diversion
Step-by-step approach to robotic cystectomy and extracorporeal urinary diversion
Urinary diversion following a radical cystectomy: techniques and outcomes
Lymph node dissection in bladder cancer surgery: step-by-step technique and outcomes
Complications after robot-assisted radical cystectomy
Robotic-assisted radical cystectomy outcomes
Robotic surgery applications for benign bladder diseases
Robotic-assisted surgery in urinary fistulas (vesicorectal, vesicovaginal, ureterovaginal)
Complications in robotic- assisted bladder surgery: preventions and management
Pediatric surgery
Robotic surgery application in urologic pediatric patients
Robotic surgery of the kidney and ureter in the pediatric population
Robotic surgery to approach bladder disorders in pediatric patients
Penile
RAIL technique and outcomes for penile cancer
Testicle
Retroperitoneal lymphadenectomy technique and outcomes for testicle cancer. - Digital[edited by] Bertrand Lombard, Philippe Céruse ; with the contribution of Nicolas Andreff [and fifty-one others].Contents:
Using the past to understand the present : a short history of digital guidance in ENT
Principles and concepts of surgical navigation
Surgical navigation in ENT
Fundamentals of surgical robotics
Surgical robots at work
The da Vinci® system: technology and surgical analysis
Transoral robotic surgery (with the da Vinci® system)
Other ENT applications of the da Vinci® system
Alternative solutions for transoral robotic surgery (TORS)
Robot-assisted endo- and transnasal surgery
Robot-based otological surgery
Robot-assisted suturing and microsurgery
Surgical simulation and training for ENT surgery
Surgical robotics: safety, legal, ethical and economic aspects
Concluding remarks.Digital Access ClinicalKey 2017 - DigitalKeith Chae Kim, editor.Summary: Robotics in General Surgery provides a comprehensive review of the current applications of the robotic platform in all the general surgery subspecialties. Additionally, for each subspecialty it serves as a procedure-oriented instruction manual in terms of technical details of procedures, including fundamentals of robot positioning and trocar placement, step-by-step description of procedures, comprehensive discussions of advantages, limitations, indications, and relative contraindications of using the robotic approach. The text also discusses the challenges and steps to overcoming these challenges in transitioning from a minimally invasive to a robotic practice/surgeon. Lastly, this volume addresses emerging technology in robotics and the impact that the robotics platform will have on not only practice of surgery, but also in the education of surgeons at all levels. Written by experts in the field of robotic surgery, Robotics in General Surgery is a valuable resource for general surgeons of all levels including residents, fellows and surgeons already in practice.
Contents:
Section 1. Overview of the Robotic System
1. History of Robotic Surgery
2. Introduction to the Robotic System
3. Overview of General Advantages, Limitations and Strategies
Section 2. Surgical Techniques: Esophagus
4. Robotic Assisted Minimally Invasive Esophagectomy
5. Robotic Assisted Operations for Gastroesophageal Reflux
6. Achalasia
Section 3. Surgical Techniques: Thoracic
7. Robotic Lobectomy Complete Port-Access Robotic Assisted Lobectomy Utilizing 3 ? Arm Technique without a Trans-Thoraric Utility Incision
8. Robotic Pulmonary Resection Using a Completely Portal Four-Arm Technique
Section 4. Surgical Techniques: Stomach
9. Gastric Cancer: Partial, Subtotal, Total Gastrectomies/ Lymph Node Dissection for Gastric Malignancies
Section 5. Surgical Techniques: Bariatric
10. Robotic Roux-en-Y Gastric Bypass
11. Robotic Sleeve Gastrectomy
12. Robotic Biliopancreatic Diversion: Robot-Assisted (Hybrid) Biliopancreatic Diversion with Duodenal Switch
Section 6. Surgical Techniques: Hepatobiliary /Pancreas
13. Robotic Pancreaticoduodenectomy (Whipple Procedure)
14. Robotic Distal Pancreatectomy
15. Robotic Hepatic Resections: Segmentectomy, Lobectomy, Parenchymal Sparing
Section 7. Surgical Techniques: Colon and Rectum
16. Robotic Right Colectomy: Four-Arm Technique
17. Robotic Right Colectomy: Three Arm Technique
18. Robotic Left Colectomy
19. Totally Robotic Low Anterior Resection
20. Robotic Hybrid Low Anterior Resection
21. Robotic-Assisted Extralevator Abdominoperineal Resection
22. Robotic Single Port Colorectal Surgery
23. Robotic Transanal Surgery
Section 8. Surgical Techniques: Endocrine
24. Robotic Thyroidectomy and Radical Neck Dissection Using a Gasless Transaxillary Approach
25. Robotic Adrenalectomy
Section 9. Surgical Techniques: Solid Organ
26. Robot-Assisted Splenectomy
27. Robotic Donor Nephrectomy and Robotic Kidney Transplant
Section 10. Surgical Techniques: Hernias
28. Robot-Assisted Ventral and Incisional Hernia Repair
Section 11. Surgical Techniques: Pediatric
29. Pediatric Robotic Surgery
Section 12. Surgical Techniques: Microsurgery
30. Robotic Assisted Microsurgery for Male Infertility and Chronic Orchialgia
Section 13. Education and Training
31. Developing a Curriculum for Residents & Fellows
32. Challenges and Critical Elements of Setting up a Robotics Program
33. Professional Education: Telementoring and Teleproctoring
Section 14. Evolving Platforms
34. Single Incision Platform
35. Tile Pro
36. ICG Flourescence
Section 15.?Future
37. Robotics and Remote Surgery: Next Step
38. The Future of Robotic Platforms. - Digitaleditor, Jess H. Lonner.Summary: This state-of-the-art book focuses specifically on the current and emerging uses of robotics for knee and hip arthroplasty, with an expanding market anticipated, particularly as costs drop, data emerges and surgical efficiencies improve. It is divided into four main sections. Part one covers the background and basic principles of robotics in orthopedic surgery, discussing its history and evolution, current concepts and available technologies, perioperative protocols for recovery and pain management, economic considerations, and risks and complications. The second and third parts focus on the techniques themselves for the knee and hip respectively, including unicompartmental and bicompartmental knee arthroplasty, patellofemoral arthroplasty, and total knee and hip arthroplasty utilizing Navio, Mako, iThink, Omni and ROSA Knee robots. The final section presents the emerging use of robotics in spine surgery as well as for hospital process improvement. Presenting the most current techniques, technology and evidence, Robotics in Knee and Hip Arthroplasty will be a valuable resource for orthopedic surgeons, residents and fellows looking to implement and utilize these developing management strategies in their clinical practice.
Contents:
Part I: Basic Principles
A Brief History of Robotics in Surgery
Evolution of Robotics in Arthroplasty
General Concepts in Robotics in Orthopedics
Learning Curve for Robot- and Computer-Assisted Knee and Hip Arthroplasty
Perioperative Protocols to Facilitate Early Discharge and Rapid Recovery after Robotic Surgery
Perioperative Pain Management Protocols for Robotic-Assisted Knee and Hip Arthroplasty
Cost Effectiveness Analysis of Robotic Arthroplasty
Risks and Complications of Autonomous and Semi-Autonomous Robotics in Joint Arthroplasty
Part II: Techniques: Knee
Unicompartmental Knee Arthroplasty Technique: NAVIO
Unicompartmental Knee Arthroplasty Technique: Makp
Patellofemoral Arthroplasty Technique: NAVIO
Patellofemoral Arthroplasty Technique: Mako
Bicompartmental Knee Arthroplasty Technique: NAVIO
Bicompartmental Knee Arthroplasty Technique: Mako
Total Knee Arthroplasty Technique: NAVIO
Total Knee Arthroplasty Technique: Mako
Total Knee Arthroplasty Technique: OMNIBotics
Total Knee Arthroplasty Technique: ROSA® Knee
Total Knee Arthroplasty Technique: Think
Part III: Techniques: Hip
Total Hip Arthroplasty Technique: Mako
Total Hip Arthroplasty Technique: Think
Part IV: Emerging Uses
Robotics in Spine Surgery
Emerging Robotic Technologies and Innovations for Hospital Process Improvement. - Digitaledited by Jorge Alvaro González Martínez, Francesco Cardinale.Summary: This book provides a state-of-the art review of this field and demonstrates the basic applications of robotic surgery in the field of neurosurgery, exposing its basic principles, practical technical nuances, and advantages and limitations related to the technology. It also provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information. Robotics in Neurosurgery: Principles and Practice will serve as a valuable resource for clinicians, surgeons, engineers and researchers dealing with, and interested in, this challenging and promising field in robotics applied to neurosurgery.
Contents:
Part I General Principles
1. Robotics in Neurosurgery: Overture
2. Historical Perspectives
3. General principles of robotics
4. Image Guidance for Intracranial Surgery with Supervisory-Control Robots
Part II Robot Assisted Neurosurgery: Clinical Applications
5. Robotics in Functional Neurosurgery
6. Robotics in Epilepsy Surgery
7. Robotic SEEG-guided radiofrequency thermal ablation
8. Robotics in Laser Ablation Procedures
9. Nuances of Robotics Applied in Children
10. Robotic Assisted Endoscopy
11. Robot-assisted stereotactic biopsy
12. Robot-assisted drug delivery to the brain
13. Robotics in Radiosurgery
14. Robotic Navigated Laser Craniotomy: Current applications and future developments.
15. Small footprint stereotactic robotic devices
16. Robotics in Spine Procedures
Part III Rehabilitation and Assistive Robots
17. Rehabilitation and assistive robotics: shared principles and common applications
18. A brief summary of the article: An exoskeleton controlled by an epidural wireless brain-machine interface in a tetraplegic patient: a proof-of-concept demonstration
Part IV Special Topics
19. Robotics in Neurosurgical Training. - DigitalJesse C. Selber, editor.Summary: This book describes the current state of robotics in plastic and reconstructive surgery. It examines existing clinical applications, emerging and future applications and evolving technological platforms. Concise yet comprehensive, this book is organized into four sections. It begins with an introduction to robotic microsurgical training and robotic skills assessment, including crowd-sourced evaluation in surgery. Section two explores a variety of robotic clinical application, including robotic breast reconstruction, robotic mastectomy, robotic cleft palate surgery and robotic microsurgery in a urologic private practice. Following this, section three addresses the opportunities and challenges an interested surgeon might face when considering incorporating this technology into their practice. To close, the final section discusses new microsurgical robotic platforms and the potential directions this technology may take in the future. Supplemented with high quality videos and images, Robotics in Plastic and Reconstructive Surgery is an invaluable resource for both plastic surgeons and multi-specialty micro-surgeons.
Contents:
Section 1: Training and Evaluation
1. Robotic Microsurgical Training
2. Robotic Skills Assessment-crowd-Sourced Evaluation in Surgery and Future Directions in Plastic Surgery
Section 2: Clinical Applications
3. Robotic Harvest of the Rectus Abdominis Muscle
4. Robotic breast reconstruction with the Latissimus Dorsi Flap
5. The RoboDIEP: Robotic Assisted Deep Inferior Epigastric Perforator Flaps for Breast Reconstruction
6. Robotic Nerve and Upper Extremity Surgery
7. Robotic Cleft Palate Surgery and Simulation
8. Robotic Microsurgery in Urology Private Practice: Advantages and Outcomes
9. Robotic nipple-sparing mastectomy with immediate prosthetic breast reconstruction
Section 3: Considerations for a Robotic Plastic Surgery Practice
10. Incorporating robotics into a plastic surgery practice
Section 4: New Microsurgical Robotic Platforms
11. Development of a New Robotic Platform for Microsurgery
12. A dedicated robotic system for open (super)microsurgery. - Digitaleditors: Charles M. Court-Brown, MD, DRCS, ED (Orth), Professor of Orthopaedic Trauma, Royal Informary of Edinburgh, Edinburgh, United Kingdom, James D. Heckman, MD, Editor-in-Chief, The Journal of bone & Joint Surgery, Needham, Massachusetts, Clinical Professor of Orthopaedic Surgery, Harvard Medical School, Visiting Orthopaedic Surgeon, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, Margaret M. McQueen, MD, FRCS, Ed (Orth), Professor of Orthopaedic Trauma, Royal Informary of Edinburgh, Edinburgh, United Kingdom, William M. Ricci, MD, Professor and Chief, Orthopaedic Trauma Service, Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, Paul Tornetta III, MD, Professor and Vice Chairman, Department of Orthopaedic Surgery, Boston University School of Medicine, Director of Orthopaedic Trauma, Boston Medical Center, Boston, Massachusetts, ; associate editor, Michael D. McKee, MD, FRCS(C), Professor, Upper Extremity Reconstructive Service, Department of Surgery, Division of Orthopaedics, St. Michael's Hospital and the University of Toronto, Toronto, Canada.Summary: "The 8th edition of Rockwood and Green's Fractures in Adults continues with the changes that were instituted in the 7th edition. In this edition there are two more chapters and 61 new authors drawn from three continents and eleven different countries... In addition, many of the new authors represent the next generation of orthopaedic trauma surgeons who will be determining the direction of trauma management over the next two or three decades"-- Provided by publisher.
Contents:
V. 1.
Biomechancis of fractures and fracture fixation
Classification of fractures
The epidemiology of fractures and dislocations
Bone and cartilage healing
Biologic and biophysical technologies for the enhancement of fracture repair
Principles of nonoperative fracture treatment
Principles of internal fixation
Principles of external fixation
Management of the multiply injured patient
Initial management of open fractures
Gunshot and wartime injuries
Principles of mangled extremity management
Post-traumatic stress disorder
Amputations
Bone and soft tissue reconstruction
Outcome studies in trauma
Imaging considerations in orthopedic trauma
Computer-aided orthopedic surgery in skeletal trauma
Osteoporosis
Fractures in the elderly patient
Stress fractures
Pathologic fractures
Periprosthetic fractures
Venous thromboembolic disease in patients with skeletal trauma
Complex regional pain syndrome
Orthopedic infections and osteomyelitis
Principles of nonunion treatment
Principles of malunions
Acute compartment syndrome
Hand fractures and dislocations
Carpus fractures and dislocations
Fractures of the distal radius and ulna
Diaphyseal fractures of the radius and ulna
Elbow fractures and dislocations
Distal humerus fractures
Humeral shaft fractures
Proximal humeral fractures
Clavicle fractures
Scapular fractures
Glenohumeral instability
Acromioclavicular joint injuries
Injuries to the sternoclavicular joint
V. 2.
Principles of spine trauma care
Cervical spine fractures and dislocations
Thoracolumbar spine fractures and dislocations
Pelvic ring fractures
Acetabulum fractures
Hip dislocations and fractures of the femoral head
Femoral neck fractures
Intertrochanteric fractures of the hip
Subtrochanteric femur fractures
Femoral shaft fractures
Distal femur fractures
Patella fractures and extensor mechanism injuries
Tibial plateau fractures
Knee dislocations
Tibia and fibula shaft fractures
Pilon fractures
Ankle fractures
Fractures and dislocations of the talus
Calcaneus fractures
Fractures and dislocations of the midfoot and forefoot.Digital Access Ovid 2015 - Digitaleditor, Paul Tornetta III, William M. Ricci, Robert F. Ostrum, Margaret M. McQueen, Michael D. McKee, Charles M. Court-Brown.Contents:
V. 1
Section One: General principles
Basics
Principles and biomechanics of fracture teatments
Management principles of special circumstances
Complications and adverse outcomes
Section Two: Upper extremity
V. 2
Section Three: Axial skeleton, pelvis and acetabulum
Section Four: Lower extremity.Digital Access - Digital[edited by] Charles A. Rockwood, Jr., Frederick A. Matsen, III, Michael A. Wirth, Steven B. Lippitt, Edward V. Fehringer, John W. Sperling ; associate editors, Samuel Antuña, Aaron J. Bois, Frank A. Cordasco, Jason E. Hsu.Contents:
Developmental anatomy of the shoulder and anatomy of the glenohumeral joint
Gross anatomy of the shoulder
Clinical evaluation of shoulder problems
Radiographic evaluation of shoulder problems
Effectiveness evaluation of the shoulder
Fractures of the proximal humerus
Fractures of the scapula
Fractures of the clavicle
Disorders of the acromioclavicular joint
Disorders of the sternoclavicular joint
Sepsis of the shoulder : molecular mechanisms and pathogenesis
Fractures, dislocations, and acquired problems of the shoulder in children
Glenohumeral instability
The rotator cuff
Shoulder arthroscopy
Glenohumeral arthritis and its management
The biceps tendon
Nerve problems related to the shoulder
The stiff shoulder
The shoulder in athletes
Occupational shoulder disorders
Tumors and related conditions.Digital Access ScienceDirect 2017 - DigitalFrederick A. Matsen, Frank A. Cordasco, John W. Sperling, Steven B. Lippitt.Digital Access ClinicalKey 2022
- Digitaleditors, John M. (Jack) Flynn, MD, Associate Professor of Orthopaedic Surgery, University of Pennsylvania School of Medicine, Associate Chief of Orthopaedic Surgery, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, David L. Skaggs, MD, Chief of Orthopaedic Surgery, Choildren's Hosptal Los Angeles, Professor of Orthopaedic Surgery, University of Southern California School of Medicine, Los Angeles, California, Peter M. Waters, MD, Clinical Chief of Orthopaedic Surgery, Boston Children's Hospital, Professor of Orthopaedic Surgery, John E. Hall Professor of Orthopaedic Surgery, Harvard Medical School, Boston, Massachusetts.Summary: "For the gold-standard resource on pediatric fractures, reach for Rockwood and Wilkins' Fractures in Children. Written by leading orthopaedic surgeons from around the world, the revised and expanded 8th edition of this classic bestselling text presents complete, up-to-date coverage of all types of children's fractures. A must-read for pediatric orthopedic surgeons and orthopedic residents. Features: NEW expanded coverage of pain medicine and casting; NEW 6 new authors from around the world; NEW time-saving outline template for easy quick-reference. Step-by-step instructions and expert guidance on numerous operative and management techniques. Author's Preferred Technique section includes algorithms explaining why the author chose that procedure. Pearls and Pitfalls and preventive measures listed for all procedures. NEW 13 full length procedural videos. Casting, remodeling and unique features of children's fractures. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: Complete content with enhanced navigation, A powerful search that pulls results from content in the book, your notes, and even the web, Cross-linked pages, references, and more for easy navigation, Highlighting tool for easier reference of key content throughout the text, Ability to take and share notes with friends and colleagues, Quick reference tabbing to save your favorite content for future use, 13 full length procedural videos"--Provided by publisher.
Contents:
Epidemiology of fractures in children
The immature skeleton
Pain management and procedural sedation for the injured child
Cast and splint immobilization, remodeling and special issues of children's fractures
Management of the multiply injured child
Compartment syndrome in children
Physeal injuries and growth disturbances
Pathologic fractures
The orthopedic recognition of child maltreatment
Fractures and dislocations of the hand and carpal bones in children
Fractures of the distal radius and ulna
Diaphyseal radius and ulna fractures
Radial neck and olecranon fractures
Monteggia fracture-dislocation in children
Evaluation of pediatric distal humeral fractures
Supracondylar fractures of the distal humerus
T-condylar distal humerus fractures
Dislocations of the elbows, medial epicondylar humerus fractures
Lateral condylar and capitellar fractures of the distal humerus
Distal humeral physeal, medial condyle, lateral epicondylar, and other uncommon elbow fractures
Humeral shaft and proximal humerus, shoulder dislocation
Clavicle and scapula fractures: acromioclavicular and sternoclavicular injuries
Cervical spine injuries in children
Thoracolumbar spine fractures
Pelvic and acetabular fractures
Fractures and traumatic dislocations of the hip in children
Femoral shaft fractures
Fractures of the distal femoral physis
Proximal tibial physeal fractures
Intra-articular injuries of the knee
Fractures of the shaft of the tibia and fibula
Ankle fractures
Fractures and dislocations of the foot.Digital Access Ovid 2015 - Digitaleditors, Peter M. Waters, David L. Skaggs, John M. (Jack) Flynn.Digital Access
- DigitalWeihua Gong, editor.Summary: This book introduces transplantation in rodents as useful tools used in studying transplant immunobiology. Several solid organs (kidney, heart, liver) transplant models in rodents are described in this book. It can help surgical quality and save surgical time. The first part of the book provides a review of rodent transplant tolerance induction, the role of gender and body-weight in rodent transplantation, surgical instruments and organ preservation solutions. In the second part of the book, various organ-transplantation techniques in rodents are discussed in individual chapters. This book presents uniform surgical procedures in mouse and rats, which produce comparable data, efficiently enhancing the translational research from bench to non-human primates and beyond. It will be of great value to transplant researchers, research fellows and clinicians in many surgical specialties. Editor Weihua Gong is an Associate Professor at the Department of Surgery, the 2nd Affiliated Hospital of Zhejiang University, China.
Contents:
Rodent Transplantation Medicine
T Cell Costimulatory Molecules
Age in Rodent Organ Transplantation
Role of Gender in Animal Transplantation
Role of Body-Weight/Functioning Mass of Graft in Rodent Transplantation
Illustration of Laboratory Facilities and Microsurgical Instruments
Organ Preservation
Rat Kidney Transplantation
Rat Orthotopic Liver Transplantation
Mouse Skin Transplantation
Mouse Heterotopic Abdominal Heart Transplant Model
Mouse Heterotopic Cervical Heart Transplant Model
Mouse kidney Transplantation
Mouse Liver Transplantation.Digital Access Springer 2015 - DigitalWeihua Gong, editor.Summary: This book introduces transplantation in rodents as useful tools used in studying transplant immunobiology. Several solid organs (kidney, heart, liver) transplant models in rodents are described in this book. It can help surgical quality and save surgical time. The first part of the book provides a review of rodent transplant tolerance induction, the role of gender and body-weight in rodent transplantation, surgical instruments and organ preservation solutions. In the second part of the book, various organ-transplantation techniques in rodents are discussed in individual chapters. This book presents uniform surgical procedures in mouse and rats, which produce comparable data, efficiently enhancing the translational research from bench to non-human primates and beyond. In this second edition, authors updates its recent progress. In addition, 3 chapters in mouse organ transplantation are added. It will be of great value to transplant researchers, research fellows and clinicians in many surgical specialties.
Contents:
Rodent Transplantation Medicine
T-Cell Costimulatory Molecules
Age in Rodent Organ Transplantation
Role of Gender in Animal Transplantation
Role of Body Weight/Functioning Mass of Graft in Rodent Transplantation
Illustration of Laboratory Facilities and Microsurgical Instruments
Organ Preservation
Rat Kidney Transplantation
Rat Orthotopic Liver Transplantation
Mouse Skin Transplantation
Mouse Heterotopic Abdominal Heart Transplant Model
Mouse Heterotopic Cervical Heart Transplant Model
Mouse Kidney Transplantation
Mouse Liver Transplantation
Mouse islet transplantation
Mouse corneal transplantation
Mouse hemopoietic stem cell transplantation
Xenotransplantation. - Digitaleditors, Wynne Morrison, MD, MBE, Critical Care and Palliative Care Director, Pediatric Advanced Care Team, The Children's Hospital of Philadelphia, Associate Professor, Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, Kristen Nelson McMillan, MD, Assistant Professor, Pediatric Critical Care, Departments of Anesthesiology and Critical Care Medicine and Pediatrics, Division of Pediatric Anesthesia and Critical Care Medicine, Director of Pediatric Cardiac Critical Care, Medical Director of Pediatric Ventricular Assist Device Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, Donald H. Shaffner, MD, Associate Professor, Departments of Anesthesiology and Critical Care Medicine and Pediatrics, Division of Pediatric Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.Summary: "Portable and easy to use, Rogers’ Handbook of Pediatric Intensive Care, Fifth Edition, contains key information from the best-selling Rogers’ Textbook in a handy format designed for everyday use. Nearly 100 chapters offer a clinically relevant synopsis of core information needed for quick reference and safe practice in the PICU." --Publisher's website.
Contents:
Contributors
Preface
Preface to previous edition
Part I. Emergency Care and Acute Management
Section 1. Initial Stabilization
Section II. Environmental Crises
Section III. Life-Support Technologies
Part II. Critical Care Organ Systems
Section I. Respiratory Disease
Section II. Neuromuscular Disease
Section III. Neurologic Disease
Section IV. Cardiac Disease
Section V. Immunologic Diseases
Section VI. Infectious Diseases
Section VII. Nutritional and Gastrointestinal Disorders
Section VIII. Renal, Endocrine and Metabolic Disorders
Section IX. Oncologic and Hematologic Disorders
Index.Digital Access - PrintShaffner, Donald H.; McCloskey, John J.; Hunt, Elizabeth Anne; Tasker, Robert C.; Rogers, Mark C.Digital Access
- Digitaleditors: David G. Nichols, MD, MBA, Professor of Anesthesiology and Critical Care Medicine and Pediatrics, Johns Hopkins University School of Medicine (on leave), Baltimore, Maryland, President and CEO, the American Board of Pediatrics, Chapel Hill, North Carolina, Donald H. Shaffner, MD, Associate Professor, Departments of Anesthesiology and Critical Care Medicine and Pediatrics, Director, Division of Pediatric Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland ; section editors: Andrew C. Argent, MBBCh, MMed, MD, FCPaeds, [and 25 others].Contents:
pt. One: Critical care integration
Sect. I: Introduction to the practice of pediatric critical care
Sect. II: Professionalism, leadership, and systems-based practice
Sect. III: Information management
Sect. IV: Ethical and palliative concerns in the care of the critically ill
Sect. V: Basic science concepts of pediatric critical care
pt. Two: Emergency care and acute management
Sect. I: Initial stabilization
Sect. II: Environmental crises
Sect. III: Life-support technologies
pt. Three: Critical care organ systems
Sect. I: Respiratory disease
Sect. II: Neuromuscular disease
Sect. III: Neurologic disease
Sect. IV: Cardiovascular disease
Sect. V: Immunologic diseases
Sect. VI: Infectious diseases
Sect. VII: Nutritional and gastrointestinal disorders
Sect. VIII: Renal, endocrine, and metabolic disorders
Sect. IX: Oncologic and hematologic disorders.Digital Access - Digitaledited by Julie G. Stewart, Susan M. DeNisco.Contents:
Historical perspectives : the art and science of nurse practitionering
Family-focused clinical practice : considerations for the nurse practitioner
Vulnerable populations
Mental health and primary care : a critical intersection
Cultural sensitivity and global health
Clinical education, case presentation, consultation and collaboration in primary care
Evidence based practice
Clinical prevention/community and population health
Electronic health record and impact on healthcare outcomes
Palliative care and chronic disease management
Concepts of the professional
Health policy and the nurse practitioner
Quality, safety and prescriptive authority
Mentoring
Reimbursement for nurse practitioner services
Professional employment.Digital Access R2Library 2019Limited to 1 simultaneous user - Digital[edited by] Susan M. DeNisco.Summary: "Role Development for the Nurse Practitioner, Third Edition is an integral text that guides students in their transition from the role of registered nurse to nurse practitioner. The text provides a comprehensive framework for interactive discussions on the role of the nurse practitioner, giving students a full understanding of the skills and knowledge needed for this dynamic profession. The Third Edition employs a variety of nurse practitioner real-world stories to illustrate important points and to assist in the transition from RN to NP. It is also the only role development textbook specific for nurse practitioners interested in entering primary care, providing a great amount of detail to the unique issues of nurse practitioners and NP students. The text also offers assignments for student role development seminars, as well as discussion questions and case examples. Key Features:This textbook is used to enhance family theory, evidence-based practice, quality improvement, population health and role transition courses"-- Provided by publisherDigital Access R2Library 2023Limited to 1 simultaneous user
- Digital[edited by] Kathleen Masters.Summary: "Role Development in Professional Nursing Practice, Fifth Edition focuses on the progression of the professional nursing role. The major themes addressed throughout the text include: teamwork and collaboration, communication, leadership, quality improvement and safety, evidence-based practice and informatics. These competencies are essential for undergraduate nursing students, providing them with a solid foundation for a successful career. The Fifth Edition maintains its focus on professional role socialization and integrates the Nurse of the Future Competency Model throughout the text.It will feature new chapters on nursing competencies and system-based practice and leadership.New to the Fifth Edition: New chapter on nursing competencies New content system-based practice and leadershipUpdated Navigate 2 Advantage Access course"--Provided by publisher.Digital Access R2Library 2020Limited to 1 simultaneous user
- DigitalRam Roth, Elizabeth A.M. Frost, Cliford Gervirtz, editors, Carrie L.H. Atcheson, associate editor.Contents:
Part I: Evolution and Development of Missions
Medical Missions: A Short History from There to Here
The Evolution of Surgical and Humanitarian Missions
The Global Burden of Surgical Need
Comparative Economics of Anesthesia Care and the Global Anesthesia Workforce
Planning a Mission, Fundraising, and Building a Team: The Kybele Experience
Organizing and Developing Universal Anesthetic Equipment
Materials Management
What do Patients and Communities Expect of a Medical Mission?
Anesthesia in Resource-Poor Settings: The Mďecins sans Frontir̈es Experience
Quality Care: Maintaining Safety Through Minimum Standards
Legal and Ethical Issues in Global Health: A Trip through the Vagaries of Truth and Culture
Part II: Specific Case Related Implementation
Strategies for Patient Assessment and Scheduling
Postoperative Follow-up and Quality Maintenance
Women?s Rights and the Right to Pain Relief in Surgery and Labor
Saving Sight In Developing Countries
Cardiac Anaesthesthesia in Low Resource Settings
Anesthesia Considerations for Facial Deformity Repair in Lesser Developed Countries
Implementing a Regional Anesthesiology Service in a Low Resource Setting
The Management of Pain in Less Developed Countries
Living the Mission in Serbia and Other Less Affluent Worlds
Anesthetic Management During the Lebanese Civil War
Trauma, War, And Managing Vascular And Orthopedic Injuries
Emergency Deployment in Disaster Areas
Part III: Education at Home and Abroad
Missions as a Part of Medical Education and the Residency Curriculum
Global Health Programs in Academic Centers.- Closing the Professional Gap in Europe Through Education
The Role of the Visiting Anesthesiologist in In-Country Education
Letters (Lessons) from Around the World (Vignettes)
The Future of Anesthesiology and Global Health in a Connected World. - Digitaledited by Nicholas Johnson.Contents:
A short introduction to disease emergence / Nicholas Johnson
Patterns of foot-and-mouth disease virus distribution in Africa / Miriam B. Casey [and eleven others]
Paroviruses of carnivores / Andrew B. Allison and Colin R. Parrish
Rabies / Conrad Freuling [and four others]
Lassa fever / Elisabeth Fichet-Calvet
Henipaviruses / Glenn A. Marsh and Lin-Fa Wang
The role of birds in the spread of West Nile virus / Paul Gale and Nicholas Johnson
Rift Valley fever virus / Janusz T. Paweska and Petrus Jansen van Vuren
From simian to human immunodeficiency viruses (SIV to HIV) / Denis M. Tebit and Eric J. Arts
Hantavirus emergence in rodents, insectivores and bats / Mathias Schlegel [and four others]
Nipah virus / David T.S. Hayman and Nicholas Johnson
Synthesis / Philip R. Wakeley, Sarah North and Nicholas Johnson.Digital Access ScienceDirect 2014 - DigitalDirk Lange, Ben Chew, editors.Contents:
1. Bacteria in the Genitourinary Tract
2. Overview of Urinary Tract Infections
3. Pathogenic Mechanisms of Uropathogens
4. Urosepsis- Pathogenesis and Treatment
5. Struvite Stone Formation by Ureolytic Biofilm Infections
6. The Management of Infection Stones
7. The Use of Bacteria to Treat Recurrent Calcium Oxalate Kidney Stone Disease
8. Role of Oxalobacter Formigenes Colonization in Calcium Oxalate Kidney Stone Disease
9. BCG for the Treatment of Non-Muscle Invasive Bladder Cancer.Digital Access Springer 2016 - DigitalDirk Lange, Kymora B. Scotland, editors.Summary: This updated volume provides a concise guide to the pathogenic, therapeutic, and preventative roles of bacteria in urology. New chapters discussing the involvement of the microbiome in the areas of recurrent kidney stone disease, female urology, and prostate cancer are included. The treatment of urosepsis, stone management, genitourinary malignancy, stone sequencing, and the role of microbiome and virome in urology are also covered. The Role of Bacteria in Urology is relevant to both clinicians and scientists interested in the infection of the genitourinary system.
Contents:
Intro; Preface; Contents;
1: Bacteria in the Genitourinary Tract: The Microbiota and Efforts to Address Infection; Introduction; The Microbiome and Its Significance in Urology; Probiotics and Urological Diseases; Cranberry Juice; References;
2: Overview of Urinary Tract Infections; Cystitis; Pathogenesis; Uropathogenic E. coli; Staphylococcus saprophyticus; Enterococcus faecalis; Streptococcus agalactiae (GBS); Clinical Management, Treatment, and Preventive Measures; Pyelonephritis; Mechanisms of Bacterial Pathogenesis; Differences Between E. coli Strains in Pyelonephritis and Cystitis Clinical Management, Treatment, and Preventive MeasuresUrethritis; Clinical Management, Treatment, and Preventive Measures; Microbiome of the Urinary Tract; References;
3: Pathogenic Mechanisms of Uropathogens; Introduction; Bacterial Adhesion; Type 1 Fimbriae; P Fimbriae; S Fimbriae and F1C Fimbriae; Non-fimbriated Adhesins; Biofilms and Related Communities; Biofilms; Intracellular Biofilm Communities (IBCs); Quiescent Intracellular Reservoirs (QIRs); Toxins and Nutrient Acquisition; Hemolysin A; Cytotoxic Necrotizing Factor; Iron Acquisition; Urease; Surviving Antimicrobials; References
4: Urosepsis: Pathogenesis and TreatmentClinical Introduction; Sources and Pathogenesis of Urosepsis; Management; Prior Sepsis Scoring; Conclusion; References;
5: The Microbiome in the Testis: Epididymitis and Orchitis; Introduction; Epidemiology; Epididymitis; Definition and Classification; Presentation; Pathogenesis and Etiology; Investigations; Complications; Management; Orchitis; Epidemiology; Definition and Classification; Presentation; Pathogenesis and Etiology; Investigations; Complications; Management; Chronic Scrotal Pain; Testis Microbiome: Future Directions of Research; References
6: Struvite Stone Formation by Ureolytic BiofilmsFormation of Struvite Stones by Ureolytic Microorganisms; Biofilm Development and Struvite Precipitation; Investigation of Struvite Stone Formation Using In Vitro and In Silico Techniques; Summary; References;
7: Management of Infection Stones; Introduction; References;
8: The Use of Probiotics and Other Microbiota Therapies to Mitigate Recurrent Calcium Oxalate Stone Formation; Introduction; The Role of CaOx in Stone Disease; Treatment of CaOx Stone Disease; Microbiome Damage and Stone Formation; Environmental Damage to the Microbiota Microbiome Restoration TherapiesProbiotics; O. formigenes; the Bacterial Proto-oxalate Utilizer in Humans; Oxalobacter Replacement; Lactic Acid Bacteria-Based Probiotics; Engineered Microbial Solutions; Fecal Microbiome Transplantation (FMT); Conclusion; References;
9: Role of Oxalobacter formigenes Colonization in Calcium Oxalate Kidney Stone Disease; Microbiology of O. formigenes; O. formigenes in the Human Gut; O. formigenes Colonization; O. formigenes Colonization and Risk of Calcium Oxalate Stone Disease; Conclusions; ReferencesDigital Access Springer 2019 - DigitalKenneth V. Honn, Darryl C. Zeldin, editors.Summary: This book examines the role of bioactive lipids as pro- and anti-inflammatory mediators in the diagnosis of and as novel therapies for cardiovascular disease, cancer, ocular and neurologic diseases, and inflammatory conditions. The major pathways of arachidonic acid and omega-3 fatty acid metabolism are represented, including cyclooxygenases, lipoxygenases, cytochrome P450 monooxygenases, specialized pro-resolving mediators, endocannabinoids, and ceramide and other sphingolipids. This book would be of great interest to basic and translational researchers, as well as physician-scientists working on selected topics (e.g., cancer, cardiovascular disease, stroke, diabetes, inflammation, etc.) in which the underlying role of lipid mediators in the pathophysiology is known or suspected. This compilation of peer-reviewed manuscripts represents reviews of timely topics presented at the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases. Authors selected are outstanding junior investigators representative of future leaders in the field of bioactive lipids.
- DigitalFaisal A. Alzahrani, Islam M. Saadeldin, editors.Summary: This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes' role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.
Contents:
Chapter 1. Isolation and characterization of extracellular vesicles: classical and modern approaches
Chapter 2. Characterization and fine structure of exosomes
Chapter 3. Extracellular vesicles mediate the embryonic-maternal paracrine communication
Chapter 4. The interplay between oviduct-derived exosomes and cumulus-oocyte complexes
Chapter 5. The interplay between exosomes and spermatozoa
Chapter 6. Mesenchymal stem cell-derived exosomes and regenerative medicine
Chapter 7. Therapeutic Potential of Mesenchymal Stem/Stromal Cell Derived-Exosomes
Chapter 8. Exosomes in Neurodegenerative Disorders
Chapter 9. Differential expression of exosomal microRNAs in neurodegenerative diseases
Chapter 10. Urinary exosomes as a possible source of kidney disease biomarkers
Chapter 11. Extracellular vesicles as potential therapeutic targets and biomarkers for liver disease
Chapter 12. Implications of extracellular vesicles in blood protozoan parasitic diseases
Chapter 13. Cancer cells-derived Exosomes and Metastasis
Chapter 14. Extracellular vesicles and integrins: partners in cancer progression
Chapter 15. Exosomes: the crucial element in the prostate cancer
Chapter 16. Exosomal microRNAs: Potential Biomarkers for Cancer Diagnosis, Treatment Response, and Prognosis
Chapter 17. Exosomes in drug delivery
Chapter 18. Exosomes and Supported Lipid Layers as Advanced Naturally Derived Drug Delivery Systems. - DigitalJacopo Demurtas, Nicola Veronese, editors.Summary: This book provides family doctors with a wealth of evidence-based indications and tips regarding geriatric medicine and approaches for the management of older patients, to be applied in daily practice. After discussing old and new features of healthy ageing and the approaches required in Family Medicine Consultation, the text introduces key elements of geriatric medicine such as frailty, sarcopenia, and the comprehensive geriatric assessment (CGA), before describing a range of characteristics unique to older patients in different contexts, with a dedicated section on Palliative Care. The role of polypharmacy and the importance of quaternary prevention and deprescribing are also addressed. Finally, the book emphasizes both the importance of a humanistic approach in caring and the approach of research and meta-research in geriatrics. Though many texts explore the role of primary care professionals in geriatric medicine, the role of family doctors in older people care has not yet been clearly addressed, despite the growing burden of ageing, which has been dubbed the Silver tsunami. Family physicians care for individuals in the context of their family, community, and culture, respecting the autonomy of their patients. In negotiating management plans with their patients, family doctors integrate physical, psychological, social, cultural and existential factors, utilizing the knowledge and trust engendered by repeated visits. They do so by promoting health, preventing disease, providing cures, care, or palliation and promoting patient empowerment and self-management. This will likely become all the more important, since we are witnessing a global demographic shift and family doctors will be responsible for and involved in caring for a growing population of older patients. This book is intended for family medicine trainees and professionals, but can also be a useful tool for geriatricians, helping them to better understand some features of primary care and to more fruitfully interact with family doctors.
Contents:
Introduction: Family Doctors and the Silver Tsunami: how to face the storm
Scales and Scores for comprehensive geriatric assessment in primary care
Nutritional issues of older people in primary care
Frailty and sarcopenia in primary care: current issues
The older patient with cognitive impairment in primary care
The older patient with psychiatric illness
The older patient at home
Managing incontinence
Intermediate care in older population: the role of the Family Doctor
The older patient in nursing home
The role of caregivers in older people
Red Flags in elderly care
Vaccinations in older people
The Geriatric Team: clinical and social aspects
Elder Abuse and Domestic Violence
Polipharmacy and overtreatment
Quaternary Prevention and Deprescribing
Quality or quantity of life? Supportive and palliative approach to the elderly
Dying at home
Dying in 4D (or more)
Integrating spiritual care in the frame
Dignity Therapy
Conclusions. - DigitalCaleb E. Finch.Summary: Global Air Pollution in Aging: Reading Smoke Signals is a complete reference connecting environmental pollution research to the human aging process. Since 1800, lifespans have more than doubled as infections declined and medicine improved. But the 20th century introduced a new global scourge of air pollution from fossil fuels with the potential to damage arteries, hearts and lungs that has been related to chronic exposure of air pollution from fossil fuels. Risk areas of study include childhood obesity, brain damage associated with air pollution, increased risk for autism in children and dementia in older adults. In humans and animals, air pollution stimulates chronic inflammation in different organs, and genetic vulnerability to air pollution is being recognized, particularly for carriers of the Alzheimer risk gene ApoE4.
Contents:
1. The three smokes in global mortality
2. The toxic nature of the three smokes
3. Air pollution in diseases of aging
4. Air pollution and cigarettes cloud development
5. Air pollution in our future logevity.Digital Access ScienceDirect 2018 - Digitaledited by Gordan Lauc, Irena Trbojević-Akmačić.Summary: Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycanns' functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research. Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans. The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.
Contents:
N-glycosylation
Mucin type O-GalNAc glycosylation in health and disease
Glycosphingolipids
Glycosaminoglycans
Other types of glycosylation
Extracellular vesicles and glycosylation
Quantitative genetics of human protein N-glycosylation
Epigenetic regulation of glycosylation
Glycosaminoglycans in neurodegenerative diseases
Glycosylation in autoimmune diseases
The role of glycosylation in infectious diseases
The importance of glycosylation in COVID-19 infection
The role of glycosylation in inflammatory diseases
Protein glycosylation in diabetes
Glycosylation and cardiovascular diseases
Glycosylation profiling as a biomarker of suboptimal health for chronic disease stratification
Glycosylation and aging. - DigitalDaniel J. MacPhee, editor.Contents:
Heat Shock Proteins and maternal contribution to oogenesis and early embryogenesis
The unmysterious roles of HSP90: Ovarian biology and autoantibodies
The role of heat shock factors in mammalian spermatogenesis
Heat shock protein A2 (HSPA2): Regulatory roles in germ cell development and sperm function
The potential functions of small heat shock proteins in the uterine musculature during pregnancy
The role of HSP70 in the regulation of autophagy in gametogenesis, pregnancy and parturition
Roles of Grp78 in female mammalian reproduction.Digital Access Springer 2017 - DigitalI.W. Fong.Summary: This new volume in the series Emerging Infectious Diseases of the 21st Century is a novel book on the role of microbes in the pathogenesis of common and disabling non-infectious diseases. New insights have emerged over the past several years suggesting that our commensal microflora of the gut is extremely important in regulating physiological and immune functions of the body. Covered are the perturbations of the normal composition of our endogenous microbiota, influenced by diet and genetic predispositions, as well as the mechanisms to produce common disorders such as obesity, diabetes, irritable bowel syndrome, colon cancer, and atherosclerotic vascular diseases. Also explored is the evidence suggesting that predisposition to increasingly common afflictions such as asthma and multiple sclerosis is influenced, in combination with our genetic composition, by early life exposure to environmental microbes and the time of onset of common viral infections. Chapters provide the most recent information on these disorders with regards to epidemiology, current concepts on pathogenesis and mechanisms of their biology, recent research and data on the role of microbes, analysis of their validity, and conclusive remarks and areas for future research. The Role of Microbes in Common Non-Infectious Diseases is an excellent resource for both physicians and investigators from a broad range of disciplines that will help to stimulate new concepts of disease pathogenesis, and lead to the unraveling of their mechanisms of diseases and to novel treatments. About the Author Ignatius [Bill] Fong is a Professor of Medicine at the University of Toronto and he is an author/ editor of 8 previously published books on Infectious Diseases. His research interests include topics in clinical infectious disease, HIV infection, and microbial-induced or -associated atherosclerosis.
Contents:
Irritable Bowel Syndrome and Microbial Pathogenesis
Microbes in Colon Cancer and Inflammatory Bowel Disease
The Role of Microbes in Obesity
Microbes in the Pathogenesis of Diabetes Mellitus
Asthma and Microbes: a New Paradigm
Chronic Fatigue Syndrome: Searching for a Microbial Etiology
Can Microbes Play a Role in the Pathogenesis of Alzheimer Disease?- Multiple Sclerosis and Microbes
The Role of Infections and Microbes in Atherosclerosis. - DigitalGamini Seneviratne, Junaida Shezmin Zavahir, editors.Summary: This book is about the role played by microbes in their community mode in sustaining ecosystems. The descriptions given in its chapters indicate clearly that microbial communities are more effective in delivering multifaceted benefits to the soil-plant system than those offered by microbial monocultures in planktonic modes. The role these communities play in a multitude of microbe-microbe and plant-microbe interactions have not yet been fully exploited to gain benefits in this field as well as to achieve sustainability in agriculture practices. Amply discussed are the beneficial characteristics and metabolic capacities of specific microbial groups and the use of microbial traits for the benefit of plant growth. The book suggests the need to develop new microbial technologies to utilize plant-associated microbes for increased crop productivity and agroecosystem balance in order to ensure sustainability. This also provides an effective guidance to scientists, academics, researchers, students and policy makers of the sphere to achieve the above outcomes.-- Provided by publisher.
Contents:
1. Role of microbial communities in plant-microbe interactions, metabolic cooperation and self-sufficiency leading to sustainable agriculture
2. Symbiotic interactions of phototrophic microbes : engineering synthetic consortia for biotechnology
3. Understanding agriculturally indispensable bacterial biofilms in sustainable agriculture
4. Global food demand and the roles of microbial communities in sustainable crop protection and food security : an overview
5. Sustaining productivity through integrated use of microbes in agriculture
6. Arbuscular mycorrhizal fungi for sustainable crop protection and production
7. Role of microbial communities in sustainable rice cultivation
8. Applications of soil bacterial community in carbon sequestration : an accost towards advanced eco-sustainability
9. Approach towards sustainable crop production by utilizing potential microbiome
10. Diversity, function and application of fungal iron chelators (siderophores) for integrated disease management
11. Role of microbial communities in the low-cost, sustainable treatment of pig effluent waste
12. Metal stress impacting plant growth in contaminated soil is alleviated by microbial siderophores
13. Natural and constructed cyanobacteria-based consortia for enhancing crop growth and soil fertility
14. Microbial communities based biofilmed biofertilizers enhance soil fertility and plant growth in hevea ecosystem : evidences from seedlings and immature plants. - DigitalNigel Langley, Bozena Michniak-Kohn, David W. Osborne, editors.Summary: Following the Semi-solid Microstructure Workshop sponsored by BASF and hosted by the Rutgers Center for Dermal Research, a pharmaceutical product development working group was formed. The group, known as the Q3 Working Group, selected the following five areas of focus: Particle/Globule Size and Distribution, Viscosity/Rheology/Spreadability, In Vitro Testing, State of API, State of Excipients. A committee was appointed for each of these five areas. The committees were tasked to review the literature, identify best practices, list experimental details required for an independent lab to duplicate the test, and propose scientific studies that may meaningfully advance this specific area of focus. Each committee has a chair (or co-chairs) that are the lead author(s) of the chapter. The Q3 Working Group members serve as the critical reviewers of each chapter, making suggestions that improve the quality of the document and that make each of the five chapters uniform in scope and content. Pharmaceutical development scientists that formulate topical products (creams, lotions, gels suspensions, foams, etc) and all the allied raw material suppliers, packaging suppliers, contract laboratories including CROs, CMOs and regulators need access to this book. Overall, the topic of semisolid microstructure is of equal importance to the generic pharmaceutical companies (filing Abbreviated New Drug Applications or ANDAs) and pharmaceutical companies filing New Drug Applications (NDAs). In addition to products applied to the skin, hair, and nails, The Role of Microstructure in Topical Drug Product Development crosses over and is essential reading to developers of oral suspensions, ophthalmic ointments and gels, otic suspension, vaginal semisolids and retention enemas.
Contents:
Part I
Critical Quality Attributes: 1. Rheological Characterization in the Development of Topical Drug Products
2. In Vitro Release & Permeation Tests as Critical Quality Attributes in Topical Product Development
3. Determination of Particle Size and Microstructure in Topical Pharmaceuticals
Part II
Role of API and Excipients: 4. Quality Assessment of API in Semisolid Topical Drug Products
5. The Role of Excipients in the Microstructure of Topical Semi-solid Drug Products. - DigitalKhawar Jabran.Summary: This book provides the concepts, techniques, and recent developments with regard to use of mulches in agriculture, utility of mulches for non-chemical pest control, and sustainability of crop production systems. Non-conventional means of improving the sustainability of crop production and pest control are required in the wake of environmental concerns over the use of conventional pesticides as well as the intensive use of land resources. Mulches have been used in agriculture for various purposes; however, there has been an increase in their use more recently, and scientists around the world have conducted more research to explore the benefits of mulching in various agricultural systems. Mulches have been found advantageous in non-chemical pest control, soil and water conservation, improving fertility, and improving microbial activities in the soil. While this is a topic of current importance, the information use of mulches in agricultural fields is rarely compiled in one comprehensive location to provide a full account of various aspects of mulches and their utility. This book will be helpful for researchers, growers, and students.
Contents:
Preface
Use of Mulches in Agriculture: Introduction and Concepts
Mulches for Weed Control
Mulches for Pest and Disease Managment
Mulches for Soil and Water Conservation
Mulches for Enhancing Biological Activities in Soil
Mulches for regulation of Soil Temperature
Mulches for Nutrient Addition to Soil
Index. - DigitalSheila Bonito, Hiroko Minami, editors.Summary: This book documents how nurses have shown their dedication, courage, expertise and compassion in helping communities prepare for, respond to and recover from disastrous events. It aims to inspire and equip nurses and other health professionals to help people in disaster-affected areas and contribute to community resilience. The last decade (2005-2015) has been characterized by a number of overwhelming natural disasters - tropical storms, floods, earthquakes, tsunamis; and threats of emerging infectious diseases - SARS, MERSCoV and Ebola around the world. Countries from the Asia Pacific region, such as Australia, Cambodia, China, Indonesia, India, Japan, Nepal, Philippines, Solomon Islands, South Korea, Thailand and Vanuatu, have borne the brunt of the devastation caused by these catastrophic events. Nurses from these countries have stepped in providing emergency care in hospitals and in the field, addressing public health needs in evacuation centers, supporting epidemiologic su rveillance and conducting health education, training and research, to help save lives and support communities build back better.Digital Access Springer 2017
- DigitalPawan K. Maurya, Kamal Dua, editors.Summary: This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases. The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders. Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress. Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress. -- Provided by publisher.
Contents:
Intro
Contents
About the Editors
1: Oxidative Stress and Oral Diseases
1.1 Introduction
1.2 The Role of Oxidative Stress in Oral Diseases
1.2.1 Chronic Periodontitis
1.2.2 Pathogenesis
1.2.3 The Role of Oxidative Stress
1.3 Potentially Malignant Disorders (PMDs) and Oral Cancer
1.3.1 Oral Lichen Planus
1.3.2 Oral Leukoplakia
1.3.3 Oral Cancer
1.4 Conclusion
References
2: The Role of Oxidative Stress in Chronic Liver Diseases
2.1 Introduction
2.2 Free Radicals and the Liver 2.3 The Role of Intracellular Antioxidants/Antioxidant Response Element (ARE) in CLD
2.4 The Role of Oxidative Stress in CLDs
2.4.1 Oxidative Stress in Hepatic Steatosis
2.4.2 Oxidative Stress in Hepatic Fibrosis
2.4.3 Oxidative Stress in Hepatocellular Carcinoma
2.5 Conclusion
References
3: The Role of Diverse Nanoparticles in Oxidative Stress: In Vitro and In Vivo Studies
3.1 Introduction
3.1.1 Nanoparticles Used in Antioxidant Activity
3.1.1.1 Silver Nanoparticles
3.1.1.2 Gold Nanoparticles
3.1.1.3 Zinc Oxide Nanoparticles 3.1.1.4 Antioxidant Activity of Other Nanoparticles
3.1.1.5 Antioxidant Activity of Polymer, Magnetic and Oxide Nanoparticles
3.1.1.6 Antioxidant Activity of Nanoparticles In Vivo
3.2 Mechanisms of Action
References
4: Oxidative Stress in Neurology and in Neurodegenerative Processes
4.1 Introduction
4.2 Oxidative Stress
4.3 Mitochondrial Oxidative Stress and Its Role in Neurodegenerative Diseases
4.4 Epidemiology
4.5 Pathophysiology
4.5.1 Alzheimerś Disease (AD)
4.5.1.1 Amyloid Cascade Hypothesis
4.5.1.2 Neurofibrillary Tangles (NFTs) 4.5.1.3 Cholinergic Hypothesis
4.5.2 Parkinson
4.5.2.1 Low Dopamine Levels
4.5.2.2 Low Norepinephrine Levels
4.5.2.3 Lewy Bodies
4.5.2.4 Genetic Factors
4.5.3 Huntingtonś Disease
4.5.4 Risk Modifiers
4.5.4.1 Alcohol
4.5.4.2 Education and Early-Life Experience
4.5.4.3 Mental and Leisure Activity
4.5.4.4 Smoking
4.5.4.5 Down Syndrome
4.5.4.6 Depression
4.5.4.7 Traumatic Head Injury
4.5.4.8 Cardiovascular Disease and Related Vascular Risk Factors
4.5.4.9 Anti-inflammatory Agents
4.5.5 Risk Factors for Parkinson
4.5.5.1 Age
4.5.5.2 Sex 4.5.6 Genetic Factors and Family History
4.5.6.1 Autosomal Dominant
4.5.6.2 Autosomal Recessive
4.5.7 Risk-Factor Modifier Genes
4.6 Therapeutic Options
4.6.1 Antioxidants
4.6.2 Modulation of Metal-Protein Interactions
4.7 Summary
References
5: Role of Oxidative Stress in Complexity of Respiratory Diseases
5.1 Introduction
5.1.1 Sources of Oxidative Stress
5.1.2 Pathways from Oxidative Stress to Pathology
5.1.3 Exogenous Risk Factors
5.1.4 Genetic Risk Factors
5.2 Oxidative Stress in Respiratory Diseases
5.2.1 AsthmaDigital Access Springer 2020 - DigitalMuddasarul Hoda, Shanmugam Hemaiswarya, Mukesh Doble.Summary: This book summarizes the latest research trends in phytophenolic therapy for the management of diabetes. It discusses the various mechanisms of action of phytophenolics present in food, fruits and plants that can be used to control/reverse diabetic conditions. Further, it addresses the synergistic interactions of phytophenolics with anti-diabetic drugs, as understanding them can yield valuable insights for complementary and alternative medicine. In closing, it discusses the important aspects of nanotechnology-based targeted delivery and improving the bioavailability of phenolic phytochemicals, two major areas of research in phytotherapy of diabetes.
Contents:
Diabetes: Its Implications, Diagnosis, Treatment & Management
Phenolic Phytochemicals- Sources, biosynthesis, extraction and their isolation
Food sources of Anti-Diabetic Phenolic Compounds
Mechanisms of Action of Phenolic Phytochemicals in Diabetes Management
Synergistic Behaviour of Phytophenolics with Anti-Diabetic Drugs
Polyphenol Nanoformulations with Potential Antidiabetic Properties
Pharmacokinetics and Pharmacodynamics of Polyphenols
Trends in Research and Development of Phenolic Phytochemicals as Potential Anti-Diabetic Therapeutics
Conclusions. - DigitalGirdhar K. Pandey, Swati Mahiwal.Summary: Potassium (K+) is an essential mineral macronutrient abundantly present in the cytosol which, unlike other macronutrients, is not metabolized and does not integrate into macromolecules. Compared to animal cells, K+ is more abundantly present in plant cells. Overall performance of the plant, and operation of metabolic machinery depends upon intracellular K+ homeostasis (K+ uptake and efflux) via K+ channels and transporters acting as mediators of cellular responses during plant development. Unlike animals, plants lack sodium/K+ exchangers; plant cells have developed unique transport systems for K+ accumulation and release. In Arabidopsis thaliana, 71 K+ channels and transporters have been identified and categorized into six families. Plant adaptive responses to several abiotic and biotic stresses are mediated by regulation of intracellular K+ homeostasis. In this report, we highlight the role of K+ in abiotic and biotic stresses, features of channels and transporters responsible for its homeostasis along with its evolutionary relationship, perception and sensing mechanisms, and K+ deficiency triggering different signaling cascades. Overall, this book covers the role of K+ in plants would be significantly helpful to research, academic community as well as students to understand the one of the major attributes of plant biology. -- Provided by publisher.
Contents:
Role of potassium : an overview
Potassium homeostasis
Potassium uptake and transport system in plant
Sequence, structure and domain analysis of potassium channels and transporters
Potassium in plant growth and development
Potassium in abiotic stress
Potassium deficiency : a stress signal
Potassium perception and sensing
Emerging roles of potassium in plants
Key questions and future perspective.Digital Access Springer 2020 - DigitalNaranjan S. Dhalla, Sajal Chakraborti, editors.Summary: It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors. However, when the activity of proteases is not regulated appropriately, disease processes can result, as seen in Alzheimer's disease, cancer metastasis and tumor progression, inflammation and atherosclerosis. Thus it is evident that there is an absolute need for a tighter control of proteolytic activities in different cells and tissues. Aimed at graduate students and researchers with an interest in cellular proteolytic events, Role of Proteases in Cellular Dysfunctions is the second book on Proteases in this series. The book consists of three parts in specified topics based on current literatures for a better understanding for the readers with respect to their subject-wise interests. The first section of this book covers a brief idea about the neuronal disorders and the involvement of proteases such as calpains, caspases and matrix metalloproteases (MMPs). The second section covers the deadly disease cancer and its relation to ubiquitin-proteosomal system, MMPs and serine proteases. The last section is about the role of proteases such as calpains, MMPs and serine protease as well as urokinase type plasminogen activator receptor (uPAR) in causing cardiovascular defects.
- DigitalVijay Singh Meena, editor.Summary: In any ecosystem, plant and microbe interaction is inevitable. They not only co-exist but also support each other's survival and provide sustenance in stressful environments. Agro-ecosystems in many regions around the globe are affected by high temperatures, soil salinity/alkalinity, low pH and metal toxicity. High salinity and severe draught are other major constraints affecting agricultural practices and also plants in the wild. A major limiting factor affecting global agricultural productivity is environmental stresses. Apart from decreasing yield, they also have a devastating impact on plant growth. Plants battle with various kind of stresses with the help of symbiotic associations with the rhizospheric microbes. Naturally occuring plant-microbe interactions facilitate the survival of plants under these stressful conditions. The rhizosphere consists of several groups of microbes, plant growth-promoting bacteria (PGPB) is one such group of microbes that assists plants in coping with multiple stresses and also promote plant growth. These efficient microbes support the stress physiology of the plants and can be extremely useful in solving agricultural as well food- security problems. This book provides a detailed, holistic description of plant and microbe interaction. It elucidates various mechanisms of nutrient management, stress tolerance and enhanced crop productivity in the rhizosphere, discussing Th rhizospheric flora and its importance in enhancement of plant growth, nutrient content, yield of various crops and vegetables as well as soil fertility and health. Divided into two volumes, the book addresses fundamentals, applications as well as research trends and new prospects for agricultural sustainability. Volume 1: Stress Management and Agricultural Sustainability, includes chapters offering a broad overview of plant stress management with the help of microbes. It also highlights the contribution of enzymatic and molecular events occurring in the rhizosphere due to plant microbe interactions, which in turn help in the biological control of plant disease and pest attacks. Various examples of plant microbe interaction in rhizospheric soil are elaborated to facilitate the development of efficient indigenous microbial consortia to enhance food and nutritional security. Providing a comprehensive information source on microbes and their role in agricultural and soil sustainability, this timely research book is of particular interest to students, academics and researchers working in the fields of microbiology, soil microbiology, biotechnology, agronomy, and the plant protection sciences, as well as for policy makers in the area of food security and sustainable agriculture.
Contents:
Intro; Contents; Contributors; About the Author;
Chapter 1: Rhizospheric Microbes for Sustainable Agriculture: An Overview; 1.1 Introduction; 1.1.1 Plant and Soil Microbiome Root Exudation; 1.2 Plant Growth-Promoting Character of Microbes; 1.2.1 Indole-3-Acetic Acid Production; 1.2.2 Production of Hydrogen Cyanide (HCN); 1.2.3 Production of Siderophores; 1.2.4 Other Phytohormones; 1.2.5 Nitrogen Fixation; 1.2.6 Phosphate Solubilizers; 1.2.7 Potassium Solubilizers; 1.2.8 Zinc Solubilizers; 1.3 Effect of Plant Growth-Promoting Microbes for Crop Production. 1.4 Effect of PGPR on Maintenance of Soil Fertility, Soil Health, and Nutrient Uptake1.5 Future Prospectuses; 1.6 Conclusions; References;
Chapter 2: Current Perspectives on Rhizobacterial-ƯEPS interactions in Alleviation of Stress Responses: Novel Strategies for Sustainable Agricultural Productivity; 2.1 Introduction; 2.2 Importance of PGPR-EPSs in Sustainable Agricultural Production; 2.3 Rhizobacterial Exopolysaccharides (EPSs) in Crop Productivity; 2.4 Functions of PGPR-Exopolysaccharides in Sustainable Agriculture; 2.4.1 Alleviation of Plant Pathogen Stress by Rhizobacterial EPSs. 2.4.2 Alleviation of Salt Stress by Rhizobacterial EPSs2.4.3 Alleviation of EPS-Drought Stress by Rhizobacterial EPSs; 2.4.4 Alleviation of Other Stressors by Rhizobacterial EPSs; 2.5 Rhizobial EPS-Metal Interactions for Sustained Crop Productivity; 2.6 Future Perspectives and Conclusions; References;
Chapter 3: Role of ACC Deaminase as a Stress Ameliorating Enzyme of Plant Growth-ƯPromoting Rhizobacteria Useful in Stress Agriculture: A Review; 3.1 Introduction; 3.2 Biochemical Characteristics of ACC Deaminase Enzyme; 3.3 ACC Deaminase Gene Distribution; 3.4 Mechanism of Action. 3.5 Role of Bacterial ACC Deaminase in Agriculture Under Abiotic Stress Conditions3.5.1 Heavy Metal Stress; 3.5.2 Salinity Stress; 3.5.3 Drought Stress; 3.5.4 Waterlogging or Flood Stress; 3.5.5 Temperature Stress; 3.6 Role of Bacterial ACC Deaminase in Agriculture Under Biotic Stress Conditions; 3.7 Role of ACC Deaminase in Legume-Rhizobia Symbiosis; 3.8 Role of ACC Deaminase-Producing PGPR in Sustainable Agriculture; 3.9 Conclusions; References;
Chapter 4: Toward the Unculturable Microbes for Sustainable Agricultural Production; 4.1 Introduction; 4.1.1 The Limitations of Pure Culture. 4.2 Metagenomics4.2.1 Metagenomics and Plant Growth Promotion; 4.2.2 Microbiology of Crops Explored by Metagenomics; 4.2.2.1 Rice; 4.2.2.2 Wheat; 4.2.2.3 Soybean; 4.2.2.4 Maize; 4.2.2.5 Chickpea; 4.2.2.6 Vegetables; 4.3 Our Leads; 4.4 Conclusions; References;
Chapter 5: Induction of Anatomical, Enzymatic, and Molecular Events in Maize by PGPR Under Biotic Stress; 5.1 Introduction; 5.2 Isolation and Identification of Bacterial Isolates; 5.3 PGPR As a Biocontrol Agent; 5.3.1 In Vitro Effect; 5.3.2 In Vivo Effect; 5.4 Effect of PGPR on Morphology and Anatomy of Plant Root. - DigitalVijay Singh Meena, editor.Summary: In any ecosystem, plant and microbe interaction is inevitable. They not only co-exist but also support each other's survival and also provide for sustenance in stressful environment. Agro-ecosystems of many regions around the globe are affected by multi-stress. Major limiting factors affecting the agricultural productivity worldwide are environmental stresses. Apart from decreasing yield they introduce devastating impact on plant growth as well. Plants battle with various kind of stresses with the help of symbiotic association with the microbes in the rhizosphere. Naturally existing plant-microbe interaction facilitates survival of plants under these stressful conditions. Rhizosphere consists of many groups of microbes, plant growth-promoting bacteria (PGPB) is one such group of microbes which assist plants in coping with multiple stresses and in plant growth as well. These microbes help in stress physiology of the plants and can be extremely useful in solving agricultural as well food security problems. The proposed book is split into two parts, with an aim to provide comprehensive description and highlight a holistic approach. It elucidates various mechanisms in rhizosphere of nutrient management, stress tolerance and enhanced crop productivity. The book discusses rhizospheric flora and its importance in enhancement of plant growth, nutrient content, yield of various crops and vegetables as well as soil fertility and health. Both volumes of the book addresses fundamentals, applications as well as research trends and new prospects of agricultural sustainability. Volume 2: Nutrient Management and Crop Improvement, contains chapters which cover a broad overview of plant growth promoting activities of microbes. This proposed book also highlights the contribution of nitrogen, phosphorus, potassium, iron and zinc-solubilizing microbes from rhizospheric soil to develop efficient indigenous microbial consortia to enhance the food and nutritional security. With the given content and layout the proposed book will be an all-inclusive collection of information, which will be useful for students, academicians, researchers working in the field of rhizospheric mechanisms, agricultural microbiology, soil microbiology, biotechnology, agronomy and sustainable agriculture and also for policy makers in the area of food security and sustainable agriculture. It will be of special interest to both academics and professionals working in the fields of microbiology, soil microbiology, biotechnology and agronomy, as well as the plant protection sciences. Timely, this edited and research book provides an essential and comprehensive source of material from basic to advance findings on microbes and their role in agricultural and soil sustainability.
Contents:
Intro; Contents; Contributors; About the Author;
Chapter 1: Towards Plant-Beneficiary Rhizobacteria andAgricultural Sustainability; 1.1 Introduction; 1.2 What Is Rhizosphere?; 1.3 What Is theRhizospheric Effect?; 1.4 PBR; 1.5 Mechanisms andMode ofAction ofPBR; 1.5.1 Direct Mechanism; 1.5.1.1 PBR asBiofertiliser; 1.5.1.2 BNF; 1.5.1.2.1 Symbiotic N FixationbyRhizobium-Legume Plant; 1.5.1.2.1.1 Symbiotic N Fixation byNon-legume Plant; 1.5.1.2.1.2 Anabaena-Azollae Symbiotic Association; 1.5.1.2.1.3 Associative N Fixation; 1.5.1.2.2 Non-symbiotic or Free-Living N-Fixing Bacteria. 1.5.1.3 P Bioavailability1.5.1.3.1 P Solubilization; 1.5.1.3.1.1 Mechanism ofP Solubilization by PSM; 1.5.1.3.2 P Mineralization; 1.5.1.3.3 P Mobilization; 1.5.1.3.3.1 Mode ofAction; 1.5.1.3.4 P-Solubolising Microorganisms; 1.5.1.3.5 Sulphur-Oxidising Microorganisms; 1.5.1.4 Plant-Hormone Production; 1.5.1.5 Siderophore Production toIncrease Micronutrient Availability; 1.5.2 Indirect Mechanism; 1.5.2.1 Production ofACC andMaintenance ofEthylene Levels inPlants; 1.5.2.2 ISR; 1.5.2.3 Antibiosis; 1.5.2.4 Enzyme Production; 1.5.2.5 Siderophore Production; 1.5.2.6 Rhizoremediation. 1.6 Future Strategies forSustainable Agriculture1.7 Conclusions; References;
Chapter 2: Microbes: ASustainable Approach forEnhancing Nutrient Availability inAgricultural Soils; 2.1 Introduction; 2.2 Microbe-Mediated Nutrient Release andCycling ofNitrogen; 2.3 Microbe-Mediated Phosphorus Solubilization; 2.3.1 Mineralization ofOrganic P; 2.3.2 Solubilization ofCa-Bound P; 2.3.3 Solubilization ofAl-Bound P andFe-Bound P; 2.4 Microbe-Mediated Potassium Release andIts Solubilization; 2.4.1 Potassium-Solubilizing Microbes andTheir Occurrence; 2.4.2 Potassium-Solubilizing Mechanisms. 2.4.3 Potential Role ofPotassic Biofertilizer2.5 Role ofMicroorganisms inMineralization andImmobilization ofSulphur; 2.5.1 Sulphur-Oxidizing Microorganisms (SOMs); 2.5.2 Rhizosphere Sulphur Cycle andIts Utilization; 2.6 Iron Transformation inSoil by Soil Microbes; 2.6.1 Iron Reduction; 2.6.2 Bacterial Siderophores; 2.7 Zinc Transformation; 2.8 Concluding Remarks; References;
Chapter 3: Microbial Transformation ofSulphur: AnApproach toCombat theSulphur Deficiencies inAgricultural Soils; 3.1 Introduction; 3.2 Major Sources ofSulphur inSoil andIts Various Pools. 3.3 Functions ofSulphur3.4 Cycling ofSulphur inSoils; 3.5 Sulphur Transformations inSoil; 3.5.1 Mineralization ofSoil Sulphur; 3.5.2 Immobilization ofSulphur; 3.5.3 Oxidation ofInorganic Sulphur; 3.5.3.1 Bacteria ofGenus Thiobacillus; 3.5.3.2 Green andPurple Sulphur Bacteria; 3.5.3.3 Colourless Filamentous Sulphur Bacteria; 3.5.4 Reduction ofSulphate; 3.6 Enzyme Reactions inSoil Involving Sulphur Compounds; 3.7 Groups ofMicroorganisms Involved inSulphur Transformation; 3.7.1 Chemolithoautotrophs; 3.7.2 Chemolithoheterotrophs; 3.7.3 Chemolithomesotrophs. - DigitalJeppe Praetorius, Bonnie Blazer-Yost, Helle Damkier, editors.Summary: This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF). The authors show that this barrier is crucial for maintaining important compositional differences between the blood plasma and the CSF. The choroid plexus epithelial cells also prevent the spread of infectious agents and other blood-borne entities to the brain tissue. Chapter topics range from the production of CSF by electrolyte regulation in the choroid plexus, to details on the selectively transporting nature of this barrier. Further, the authors elaborate on the important roles of CSF in sustaining brain health by providing hydration, solutes, and nutrients to the brain tissue. Readers will also learn how CSF circulates signaling molecules within the compartments of the brain and removes waste products from the brain tissue. Elucidating the regulation of these processes in the choroid plexus is not only important for the readers' understanding of normal brain development and function, but is also crucial for resolving a variety of cerebral challenges that lead to brain edema, as well as developing treatments for diseases. The book discusses disease models like hydrocephalus, sleep disorders, and age-related dementia. Its comprehensive coverage makes this volume a valuable resource for researchers in cell and neurophysiology, as well as graduate students of the neurosciences.
Contents:
Structure of the Mammalian Choroid Plexus
Blending Established and New Perspectives on Choroid Plexus-CSF Dynamics
A Frog Model for CSF Secretion
Cotransport of Water in the Choroid Plexus Epithelium: From Amphibians to Mammals
The Significance of the Choroid Plexus for Cerebral Iron Homeostasis
Acid/Base Transporters in CSF Secretion and pH Regulation
TRPV4, a Regulatory Channel in the Production of Cerebrospinal Fluid by the Choroid Plexus
Neuroprotective Mechanisms at the Blood-CSF Barrier of the Developing and Adult Brain
Roles of the Choroid Plexus in Aging
Choroid Plexus Tumors
Roles of the Choroid Plexus in CNS Infections
Hydrocephalus. - Digitaledited by Tahira Farooqui, Department of Entomology, The Ohio State University, Columbus, OH, United States ; Akhlaq A. Farooqui, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, United States.Summary: Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction. The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline. Comprehensively provides an overview of the effects of the Mediterranean diet on the brain and its beneficial effects in neurodegenerative diseases. Discusses the relationship among Type 2 Diabetes, Metabolic Syndrome and Alzheimer's Disease, and the effect of the Mediterranean diet on normal aging, longevity, and other neurodegenerative diseases. Focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative disease
Contents:
Effects of Mediterranean diet components on neurodegenerative diseases
The Mediterranean ddiet and healthy brain aging: innovations from nutritional cognitive neuroscience
Molecular and intracellular signaling mechanisms of herbs, spices, and food components in the Mediterranean diet in improving cognitive function
The molecular basis for protective effect of Mediterranean diet in neurodegenerative disorders
Multinutrient approach to slow down brain aging and related neurodegenerative disorders
Effect of Mediterranean diet on healthy brain aging: involvement of telomerase
Mediterranean diet and dementia: can this be a preventive approach?
Effects of dietary components on microglia inactivation in Alzheimer's disease
Contribution of Mediterranean diet in the prevention of Alzheimer's disease
Mediterranean diet and its impact on cognitive functions in aging
Mediterranean diet and diabetic retinopathy
Mediterranean diet as a potential strategy to reduce cognitive decline and dementia in the elderly
Effect of Mediterranean diet components on type 2 diabetes and metabolic syndrome
Interactions between age, diet, and insulin and their effect on cognition: implications for Alzheimer's disease
The use of polyphenols for the treatment of Alzheimer's disease
Neuroprotective effects of garlic in model systems of neurodegenerative diseases
Neuroprotective properties of wine: implications for the prevention of cognitive impairment
Red wine retards abeta deposition and neuroinflammation in Alzheimer's disease
Contribution of diabetes and metabolic syndrome in the pathogenesis of Alzheimer's disease
Effects of Western, Mediterranean, vegetarian, and Okinawan diet patterns on human brain
Mediterranean diet is beneficial: but, how, and why?
Multinutrient intervention in the prevention and treatment of dementia
Cardioprotective properties of wine: implications for the management of neurodegenerative diseases
Antiinflammatory properties of dietary n-3 polyunsaturated fatty acids protect against cognitive decline in aging and neurodegenerative diseases
Effects of dietary omega-3 fatty acid consumption
Interplay between lipid mediators and immune system in the promotion of brain self-repair
Importance of fruit and vegetable-derived flavonoids in the Mediterranean diet: molecular and pathological aspects
Perspective and directions for future research.Digital Access ScienceDirect 2018 - Digital/PrintCarlo Rossetti, Francesco Peri, editors.Summary: TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). This volume critically reviews the different types of TLR4 activators and inhibitors, discusses the role of molecular aggregates in agonism/antagonism as well as the pivotal role of the CD14 receptor in the modulation of TLR4 signal and the molecular details and actors of the intracellular cascade. The book presents the role of TLR4 in several pathologies, such as sepsis and septic shock caused by receptor activation by gram-negative bacterial lipopolysaccharide (LPS), in neurodegenerative and neurological diseases such as Parkinson and Alzheimer's diseases, and Amyotrophic Lateral Sclerosis (ALS). It reviews the role of TLR4 in neural stem cell-mediated neurogenesis and neuroinflammation and in Human Induced Pluripotent Stem Cells and Cerebral Organoids and discusses the emerging role of micro-RNA (miRNA) regulation by TLR4.
- DigitalGanji Purnachandra Nagaraju, editor.Summary: The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy. Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.
Contents:
Intro; Dedication; Preface; Contents; Contributors; About the Editor;
1: HGFR and FG
R2: Their Roles in Progression and Metastasis of Esophageal Cancer; 1.1 Introduction/Background; 1.2 Clinical Characteristics of Esophageal Cancer; 1.3 Structures of Hepatocyte Growth Factor Receptor (HGFR) and Fibroblast Growth Factor Receptor 2 (FGR2); 1.4 Expression and Roles of HGFR and FGFR2 in EC; 1.5 Signaling Pathways Related to HGFR and FGR2 in EC; 1.5.1 Structure and Functions of HGF and c-Met Receptors; 1.5.2 HGF-c-Met Signaling Mechanisms. 1.5.3 Role of MET Signaling in Physiologic and Pathologic Growth1.5.4 Structure, Functions, and Signaling of FGR2; 1.5.5 Role of FGFR2 in Esophageal Cancer; 1.6 Molecular-Targeted Therapy of the HGFR and FGFR2 in EC; 1.6.1 c-Met-Targeted Therapies, Adverse Reactions, and Relevant Clinical Trials; 1.6.2 FGFR-Targeted Therapies, Their Adverse Reactions, and Relevant Clinical Trials; 1.7 Economic/Financial Issues for Patients, Professionals, and Hospitals; 1.8 Conclusions and Future Perspectives; References;
2: Role of Src and VEGFR Tyrosine Kinases in Esophageal Cancer. 2.1 Introduction2.1.1 Src and Esophageal Cancer; 2.1.2 VEGFR (Vascular Endothelial Growth Factor) and Esophageal Cancer; References;
3: The Clinical and Biological Significance of Tyrosine Kinases in Gastric Cancer; 3.1 Introduction/Background; 3.2 Characterization of Gastric Cancer with Genomic and Molecular Analyses to Stratify the Heterogeneous Disease; 3.2.1 Genomics of Gastric Cancer; 3.2.2 Gene Mutations in Gastric Cancer; 3.2.3 Chromosomal Instability; 3.2.4 Transcriptional Changes in Gastric Cancer; 3.2.5 Epigenetic Modifications in Gastric Cancer. 3.2.6 Molecular and Genomic Stratification of Gastric Cancer3.3 Role of Tyrosine Kinases, Receptors, and Inhibitors in Gastric Cancer; 3.3.1 Receptor Tyrosine Kinases in Gastric Cancer; 3.3.2 Role of EGF Receptor/HER Tyrosine Kinase Family in Gastric Cancer; 3.3.3 Vascular Endothelial Growth Factor Receptor; 3.3.4 Fibroblast Growth Factor Receptor; 3.3.5 Platelet-Derived Growth Factor Receptor; 3.3.6 Combined VEGFR and PDGFR Tyrosine Kinase Inhibitors; 3.3.7 Hepatocyte Growth Factor Receptor Tyrosine Kinase; 3.4 Targeted Therapies and Ongoing Clinical Trials. 3.4.1 Targeted Therapies for HER-2 Overexpressed Gastric Cancers3.4.2 Ongoing Trials for HER-2 Targeted Therapies; 3.4.3 Targeted Therapies for the VEGF-Positive Gastric Cancers; 3.4.4 Trials for VEGF Targeted Therapies; 3.4.5 Anti-EGFR-Targeted Therapies and Trials; 3.4.6 Targeted Therapies for Gastric Cancers with FGFR2 Amplification; 3.4.7 Clinical Trials for FGFR2-Targeted Therapies; 3.4.8 Targeted Therapies for the PI3K Pathway and Clinical Trials; 3.4.9 Targeted Therapies and Clinical Trials for MET-Amplified Gastric Tumors; 3.4.10 Immunotherapy for Gastric Cancer. - PrintRalph A. Tripp, S. Mark Tompkins, editors.Summary: "This volume discusses the interactions between viruses and their host cells, and explores the roles of host and viral genes and non-coding RNAs in the virus replication cycle. During infection, viruses express a variety of genes, encoding proteins and RNAs that serve to subjugate the cell -- by redirecting cellular processes to support viral replication and, at the same time, by mitigating the cellular response to infection. In this book, experts discuss these interactions in depth, and elaborate on our current understanding of virus-cell interactions for a diverse range of viruses, including positive and negative sense RNA viruses, DNA viruses, and a vector-borne virus. The roles of non-coding RNAs are also discussed. While each class of viruses has distinct replication requirements, this volume reveals unique features and commonalities in viral replication cycles. Accordingly, it represents a valuable source of information for researchers and clinicians alike."--Back cover.
Contents:
Host factors in coronavirus replication
Roles of pro-viral host factors in mosquito-borne flavivirus infections
Role of innate genes in HIV replication
Host factors involved in ebola virus replication
Role of host genes in influenza virus replication
A functional genomics approach to henipavirus research: the role of nuclear proteins, microRNAs and immune regulators in infection and disease
Roles of non-coding RNAs in respiratory syncytial virus (RSV) infection
Roles of non-coding RNAs during herpesvirus infection. - Digitalvolume editor, Marcela Rocha de Olivera Carrilho.Contents:
Incidence, prevelance and global distribution of root caries
Etiology, risk factors and groups of risk
Specificities of caries on root surface
Root surface biofilms and caries
Endogenous enzymes in root caries
Root surface caries, rationale behind good diagnostic practice
Assessing the risk of developing carious lesions in root surfaces
Assessment of root caries lesion activity and its histopathological features
Monitoring of root caries lesions
Biofilm control and oral hygiene practices
Convential preventive therapies (fluoride) on root caries lesions
New preventive approaches part I: functional peptides and other therapies to prevent tooth demineralization
New preventive approaches part II: role of dentin biomodifiers in caries progression
Management of cavitated root caries lesions: minimium intervention and alternatives
Clinical performance of root surface restorations
Concluding remarks.Digital Access Karger 2017 - DigitalJohn Havens Cary, Howard I. Maibach, editors.Summary: This concise, comprehensive book provides the most recent updates on rosacea management strategy, pathophysiology, genetic and environmental contribution, comorbidities, and other various topics. It meets the market need for a book that examines topics that are not typically included in rosacea textbooks. Beginning with a discussion on the current clinical understanding of the disease, this book reviews the aforementioned topics in a thorough yet accessible fashion. Complete with tables detailing a variety of drugs in an unbiased manner as well as color photos of real patients, each chapter aims to relay useful, practical information to dermatologists at every stage in their career. A valuable contribution to the Updates in Clinical Dermatology Series, Rosacea aims to promote the rapid and efficient transfer of medical research into clinical practice for the benefit practitioners and patients alike.
Contents:
Intro
Preface
Contents
Contributors
1: Introduction to Clinical Rosacea
Rosacea Is a Syndrome and Not a Pathogenically Defined Disease
History of Classification of Rosacea: Distinction from Acne and Recognition of Phenotypic Subtypes
The Four Classic Phenotypic Subtypes of Rosacea Have Important Utilities
The Flawed Proposal to Eliminate the Classic Phenotypic Subtypes
The Classic Phenotypic Subtypes Are Useful and Will Persist
Incidence
History
History of Present Illness
Past Medical History
Medication History
Family History
Social History Review of Systems
Physical Exam
Differential Diagnoses
Histology
References
2: Pathophysiology of Rosacea
Introduction
Current Concepts of the Pathophysiology
Genes in Rosacea
Innate Immunity and Adaptive Immunity
Neuroimmune and Neurovascular Dysregulation
Novel Insights and Promising Targets
Future Studies
Conclusion
References
3: Genetics of Rosacea
Background
Epidemiology
Familial Inheritance Studies
Twin Concordance Studies
Gene Association Case-Control Studies
Molecular and Functional Data
Endoplasmic Reticulum (ER) Stress Toll-Like Receptor (TLR)-2
Antimicrobial Peptides
Transient Receptor Potential Vanilloid 1 (TRPV1)
Neurovascular Factors
Mast Cells
IL-17
TSLP
Associations with Comorbidities
Conclusion and Future Directions
References
4: Evidence-Based Management
Introduction
Environmental Modification
Topical Therapies
Metronidazole
Azelaic Acid
Sodium Sulfacetamide-Sulfur
Calcineurin Inhibitors
Crotamiton, Ivermectin, and Permethrin
Clindamycin
Retinoids
Systemic Therapies
Doxycycline and Minocycline
Macrolides
Antihypertensives Isotretinoin
Conclusion
References
5: Difference in Vasoconstrictors: Oxymetazoline Versus Brimonidine
Introduction
Vascular Anatomy
Brimonidine
Pharmacodynamics and Pharmacokinetics
Administration and Interactions
Indication and Clinical Management
Efficacy
Adverse Effects
Oxymetazoline
Pharmacodynamics and Pharmacokinetics
Administration and Interactions
Indication and Clinical Management
Efficacy
Adverse Effects
Oxymetazoline Versus Brimonidine
Conclusion
References
6: Treatment of Ocular Rosacea
Introduction Conservative Therapy
Topical Medical Therapy
Systemic Therapy
Procedural and Surgical Therapy
Future Directions
Conclusion
References
7: Physical Modalities for the Treatment of Rosacea
Introduction
Light and Laser Applications for Vascular Lesions
Pulsed Dye Laser (PDL)
KTP Laser
Long-Pulsed Nd:YAG Laser
Intense Pulse Light (IPL)
Summary: Therapy of Vascular Lesions
Physical Therapeutic Options in the Treatment of Phymatous Rosacea Manifestations
Dermashaving (Scalpel)
Dermabrasion
Electrosurgery (Fig. 7.1a-c)
Laser Surgery (Fig. 7.2a, b) - DigitalJohn R. Goldblum, Laura W. Lamps, Jesse K. McKenney, Jeffrey L. Myers.Contents:
Introduction : the legacies of Dr. Lauren V. Ackerman and Dr. Juan Rosai
Dermatoses
Tumors and tumorlike conditions of the skin
Upper aerodigestive tract
Mandible and maxilla
Major and minor salivary glands
Ear
Thyroid gland
Parathyroid glands
Lung
Pleura
Mediastinum
Esophagus
Stomach
Small bowel
Appendix
Large bowel
Anus
Liver : non-neoplastic diseases
Liver : tumors and tumorlike conditions
Gallbladder and extrahepatic bile ducts
Pancreas and ampullary region
Kidney : non-neoplastic diseases
Kidney : tumors and tumorlike conditions
Bladder
Prostate and seminal vesicles
Testis and testicular adnexa
Penis and scrotum
Adrenal gland and other paraganglia
Vulva
Vagina
Uterus : cervix
Uterus : corpus
Fallopian tube
Ovary
Breast
Lymph nodes
Spleen
Bone marrow
Bone and joints
Soft tissues
Cardiovascular system
Central nervous system
Pituitary gland
Eye and ocular adnexa.Digital Access ClinicalKey 2018 - DigitalJeffrey J. Schaider, MD, Roger M. Barkin, MD, MPH, Stephen R. Hayden, MD, Richard E. Wolfe, MD, Adam Z. Barkin, MD, MPH, Philip Shayne, MD, Peter Rosen, MD.Summary: "This best-selling emergency department reference is now in its thoroughly updated Fifth Edition. The foremost authorities provide practical information on over 600 clinical problems in a fast-access two-page outline format that's perfect for on-the-spot consultation during care in the emergency department.Coverage of each disorder includes clinical presentation, pre-hospital, diagnosis, treatment, disposition, and ICD-9 coding. Icons enable practitioners to quickly spot the information they need. This edition provides up-to-date information on topics such as emerging infections, new protocols, and new treatments"--Provided by publisher.Digital Access Ovid 2015
- Digital[edited by] Jeffrey J. Schaider, MD [and 5 others].Summary: "Rosen & Barkin's 5-Minute Emergency Medicine Consult has evolved to reflect the unique quality of our practice of emergency medicine. Our clinical environment provides challenges for the clinician; the remarkable breadth of clinical conditions encountered, the time constraints of an acute illness, environmental considerations, and the logistical demands of busy emergency departments (EDs). Time is of the essence! This book is designed to meet the needs of clinicians working in settings providing urgent and emergent care. To look for a diagnosis, one must think of it, and the very nature of the ED makes prolonged deliberation difficult. Nevertheless, it must become instinctive to think about the statistically rare, but clinically serious entity, rather than to just reach for the statistically probable, but non-life-threatening diagnosis"-- Provided by publisher.Digital Access
- DigitalSyed A. Hoda, Edi Brogi, Frederick C. Koerner, Paul P. Rosen.Contents:
Anatomy and physiologic morphology
Abnormalities of mammary development and growth
Inflammatory and reactive tumors
Specific infections
Papilloma and related benign lesions
Myoepithelial neoplasms
Adenosis and microglandular adenosis
Fibroepithelial neoplasms
Ductal hyperplasia: usual and atypical
Precarcinomatous breast disease: epidemiologic, pathologic, and clinical considerations
Ductal carcinoma In Situ
Invasive ductal carcinoma: assessment of prognosis with morphologic and biologic markers
Tubular carcinoma
Papillary carcinoma
Medullary carcinoma
Carcinoma with metaplasia and low-grade adenosquamous carcinoma
Squamous carcinoma
Mucinous carcinoma
Apocrine carcinoma
Mammary carcinomas with endocrine features
Small cell carcinoma
Secretory carcinoma
Mammary carcinoma with osteoclast-like giant cells
Cystic hypersecretory carcinoma and cystic hypersecretory hyperplasia
Adenoid cystic carcinoma
Invasive cribriform carcinoma
Lipid-rich carcinoma
Glycogen-rich carcinoma
Invasive micropapillary carcinoma
Paget disease of the nipple
Lobular carcinoma In Situ and atypical lobular hyperplasia
Invasive lobular carcinoma
Unusual clinical presentation of carcinoma
Metastases in the breast from nonmammary neoplasms
Benign proliferative lesions of the male breast
Carcinoma of the male breast
Breast tumors in children
Benign mesenchymal neoplasms
Sarcoma
Lymphoid and hematopoietic neoplasms of the breast
Pathologic effects of therapy
Cutaneous neoplasms
The pathology of axillary and intramammary lymph nodes
Pathologic examination of breast and lymph node specimens, including sentinel lymph nodes
Molecular classification and testing of breast carcinoma.Digital Access Ovid 2014 - DigitalEdi Brogi, Syed A. Hoda, Frederick C. Koerner, Paul P. Rosen.Summary: "Intended as the companion book to Rosen's Breast Pathology, this heavily illustrated text offers essential guidance on diagnostic evaluation of needle core biopsies"--Provided by publisher.
Contents:
Embryology, development, history, and physiologic morphology
Inflammatory and reactive lesions
Specific infections
Benign papillary tumors
Myoepithelial lesions
Adenosis and microglandular adenosis
Fibroepithelial neoplasms
Ductal hyperplasia, atypical ductal hyperplasia, and ductal carcinoma In Situ
Invasive ductal carcinoma
Tubular carcinoma
Papillary carcinoma
Medullary carcinoma
Metaplastic carcinoma including low-grade adenosquamous carcinoma
Mucinous carcinoma
Apocrine carcinoma
Adenoid cystic carcinoma
Other special types of invasive ductal carcinoma
Lobular carcinoma In Situ and atypical lobular hyperplasia
Invasive lobular carcinoma
Mesenchymal lesions
Lymphoid and hematopoietic tumors
Metastases in the breast from nonmammary malignant neoplasms
Pathologic effects of therapy
Men and children
Pathologic changes and clinical complications associated with needling procedures
Processing, pathological examination, and reporting of needle core biopsy specimens.Digital Access Ovid 2017 - Digitaleditor-in-chief, Ron M. Walls; senior editors, Robert S. Hockberger, Marianne Gausche-Hill.Digital Access ClinicalKey 2018
- Digitaleditor-in-chief, Ron M. Walls ; senior editors, Robert S. Hockberger, Marianne Gausche-Hill, Timothy B. Erickson, Susan R. Wilcox.Digital Access ClinicalKey 2023
- Digitaledited by Toby L. Simon, Jeffrey McCullough, Edward L. Snyder, Bjarte G. Solheim, Ronald G. Strauss.Contents:
Sect. I: Contemporary issues in donation and transfusion
Sect. II: Blood components and derivatives
Pt. I: Red blood cells
Pt. II: Platelets
Pt. III: White blood cells
Pt. IV: Plasma
Sect. III: Apheresis, transplantation, and new therapies
Sect. IV: Specialized clinical practice
Pt. I: Obstetrics and pediatrics
Pt. II: Surgery and trauma
Pt. III: Oncology
Sect. V: Hazards of transfusion
Pt. I: Infection hazards
Pt. II: Other hazards.Digital Access Wiley 2016 - Digitaleditors, Andreas B. Imhoff and Felix H. Savoie III.Summary: This book presents the consensus findings of the ISAKOS Shoulder Committee regarding the treatment options in patients suffering from shoulder pain and reduced function or dead arm syndrome as a consequence of rotator cuff injuries. The aim is twofold: to equip readers with a precise knowledge of the presenting characteristics of these injuries in different age groups and to describe in detail the initial management and surgical and non-surgical approaches, taking into account the age-specific features. Readers will find clear descriptions of all the latest arthroscopic techniques, which allow repair of even the largest tears. The indications for and performance of tendon transfer procedures, biceps tenotomy, tenodesis, hemiarthroplasty, anatomic shoulder arthroplasty, reverse total shoulder arthroplasty, and revision surgery are explained. Helpful guidance is also provided on the use of strategies to promote rotator cuff healing, including stem cell therapy and scaffolds. The authors are leading experts in the field, and the book will be of value for all shoulder surgeons and orthopaedic trainees and consultants, as well as sports medicine specialists.
- DigitalPatrick J. McMahon, editor.Summary: Comprised exclusively of clinical cases presenting injuries to and management of the rotator cuff, this concise, practical casebook will provide orthopedic surgeons with the best real-world strategies to properly manage the various kinds of cuff injury they may encounter. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome, literature review and clinical pearls and pitfalls. Cases included illustrate different management strategies for rotator cuff surgery, including arthroscopic repair for tendonitis and tears, open and mini-open repair for severe tears, latissimus dorsi and pectoralis tendon transfer, arthroscopic debridement, hemiarthroplasty and total reverse arthroplasty, biological augmentation, and revision repair after retear and infection. Pragmatic and reader-friendly, Rotator Cuff Injuries: A Clinic al Casebook is an excellent resource for orthopedic surgeons and sports medicine specialists confronted with both common and complex injuries to the rotator cuff.
Contents:
Preface
Arthroscopic Treatment of Rotator Cuff Tendonitis including Treatment of Acomioclavicular joint Osteoarthritis and Os Acromiale
Arthroscopic Management of Rotator Cuff Calcific Tendonitis
Arthroscopic repair of partial thickness articular sided rotator cuff tendon tears
Arthroscopic repair of full thickness small-to-moderate rotator cuff tears
Open Rotator Cuff Repair
Arthroscopic repair of subscapularis tendon tears
Arthroscopic Treatment of Combined Shoulder Instability and Rotator Cuff Tear
Arthroscopic repair of severe rotator cuff tears
Arthroscopic Debridement for Massive Rotator Cuff Tears
Open Repair of Severe Rotator Cuff Tears
Latissimus Dorsi Transfer for Severe Rotator Cuff Tears
Pectoralis Major Transfer
Hemiarthroplasty for Cuff Arthropathy
Reverse Total Shoulder Arthroplasty for Cuff Arthropathy
Adding a latissimus dorsi tendon transfer to reverse shoulder arthroplasty
Adding a bone graft to reverse TSA
Rotator Cuff Repair with Patch Tissue
Use of PRP in Rotator Cuff repair
Partial rotator cuff repair for massive rotator cuff repair
Suprascapular Nerve Release with Rotator Cuff Tears
Re-do Rotator Cuff Repair
Nonoperative Treatment of Rotator Cuff Tears.Digital Access Springer 2018 - DigitalStefano Gumina, editor.Summary: This handbook provides detailed, state of the art information on simple and complex rotator cuff tears that will be of value in daily clinical practice. It covers all relevant aspects, including basic science, pathogenesis, clinical and instrumental evaluation, and treatment techniques. Drawing on the results of recent studies, the book will enable the reader to better understand how tears occur and what treatment should be employed in different circumstances. Rotator cuff tear has always attracted great interest because it may cause shoulder pain, loss of strength, simple or complex disabilities, and partial or total inability to work, reducing quality of life. The goals of cuff repair are to restore footprint anatomy with biomechanically secure, tension-free construction that promotes biological healing at the tendon-to-bone interface. Even today, there is cause for discussion about when and how to perform surgical repair and on what to do in cases of irreparable rupture. This book casts light on such issues. It is especially designed for shoulder surgeons and rehabilitation specialists and will also be of value for residents and shoulder fellows.
Contents:
Section 1-Basic Science:1 History of shoulder pain and rotator cuff pathology.
2 Subacromial space and rotator cuff anatomy
3 Rotator cuff
4 Epidemiology and demographics of the rotator cuff tear
Section 2- Etiopathogenesis of the cuff tear: 5 Intrinsic factors (Physiologic degeneration
Aging- Smoking habit-Blood hypertension- Obesity, Hypercholesterolemia, and Diabetes
Genetics- Alchool assumption)
6 Extrinsic factors (Subacromial impingement
Acromioclavicular joint degeneration- Thoracic hyperkyphosis
Subcoracoid impingement
Other causes: pigmented villonodular synovitis)
7 Antropometrics aspects of the patients with rotator cuff tear
Section 3-clinical and instrumental evaluation: 8 Classification
9 Shoulder Pain intensity and distribution,- 10 Clinical evaluation
11 Shoulder pain due to visceral pathologies and cervical spine disorders
12 Instrumental evaluation (X-Ray and MRI- Arthro CT- Ultrasound evaluation)
Section 4- cuff tear treatment:
13 Natural history
14 The possible role of the transcription factor NF-kB on evolution of rotator cuff tear and on mechanisms of cuff tendon healing
15 Conservative treatment
16 Operating room setting
17 Anesthesiological techniques
18 Treatment of the partial tears
19 Treatment of the reparable postero-superior lesions (Arthroscopic repair- single row and double row repair technique
Suture Bridge and Transosseous Techniques- Open technique)
20 Treatment of the unreparable massive rotator cuff tear (Arthroscopic debridement-Margin Convergence- Interval slide- Partial repair- Subacromial Biodegradable Spacer- Tuberoplasty- Suprascapular nerve in association with irreparable tears- Augmentation with patches- Transfer of muscular tendineous units- Latissimus dorsi- Teres major- Pectoralis major for isolated subscapularis tear- Biceps Tenodesis Augmenting Repair)
21 Subscapularis tear: intraoperative evaluation and treatment
22 Stem cells and PRP in rotator cuff healing
23 Rehabilitation
Section 5-cuff tear arthropathy
24 Etiopathogenesis
25 Arthroscopic debridement
26 Reverse Shoulder Arthroplasty: evolution in design, indications, surgical technique, and associated complications
27 Nanostructures.Digital Access Springer 2017 - DigitalVolker Musahl, Jón Karlsson, Ryosuke Kuroda, Stefano Zaffagnini, editors.Contents:
Introduction
Historical perspective
Rotatory knee laxity
Pivot shift
Surgery for Rotatory Knee Instability
Functional rehab/RTP
Future directions.Digital Access Springer 2017 - DigitalSteven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, Christopher M. Bono [editors].Digital Access ClinicalKey 2018
- PrintWilliam Damon.Print
- PrintRogers, Wendy A.Summary: The Routledge Handbook of Feminist Bioethics is an outstanding resource for anyone with an interest in feminist bioethics, with chapters covering topics from justice and power to the climate crisis. Comprising forty-two chapters by emerging and established scholars, the volume is divided into six parts: I Foundations of feminist bioethics II Identity and identifications III Science, technology and research IV Health and social care V Reproduction and making families VI Widening the scope of feminist bioethics The volume is essential reading for anyone with an interest in bioethics or feminist philosophy, and will prove an invaluable resource for scholars, teachers and advanced students
- Digitaledited by Alan Bleakley.Summary: This authoritative new handbook offers a comprehensive and cutting-edge overview of the state of the medical humanities globally, showing how clinically oriented medical humanities, the critical study of medicine as a global historical and cultural phenomenon, and medicine as a force for cultural change can inform each other. Composed of eight parts, the Routledge Handbook of the Medical Humanities looks at the medical humanities as: a network and system therapeutic provocation forms of resistance a way of reconceptualising the medical curriculum concerned with performance and narrative mediated by artists as diagnosticians of culture through public engagement. This book describes how the medical humanities can be used in and out of clinical settings, acting as a point of resistance, redistributing medicine’s capital amongst its stakeholders, embracing the complexity of medical instances, shaping medical education, promoting interdisciplinary understandings and recognising an identity for the medical humanities as a network effect. This book is an essential read for all students, scholars and practitioners with an interest in the medical humanities.
- Printedited by Şebnem Susam-Saraeva and Eva Spišiaková.Summary: "The Routledge Handbook of Translation and Health provides a bridge between translation studies and the burgeoning field of health humanities, which seeks novel ways of understanding health and illness. As discourses around health and illness are dependent on languages for their transmission, impact, spread, acceptance and rejection in local settings, translation studies offers a wealth of data, theoretical approaches and methods for studying health and illness globally. Translation and health intersect in a multitude of settings, historical moments, genres, media and users. This volume brings together topics ranging from interpreting in healthcare settings to translation within medical sciences, from historical and contemporary travels of medicine through translation to areas such as global epidemics, disaster situations, interpreting for children, mental health, women's health, disability, maternal health, queer feminisms and sexual health, and nutrition. Contributors come from a wide range of disciplines, not only from various branches of translation and interpreting studies, but also from disciplines such as psychotherapy, informatics, health communication, interdisciplinary health science and classical Islamic studies. Divided into four sections and each contribution written by leading international authorities, this timely handbook is an indispensable resource for all students and researchers of translation and health within translation and interpreting studies, as well as medical and health humanities"-- Provided by publisher
Contents:
Introduction. Beyond translation and medicine : initiating exchanges between translation studies and health humanities / Şebnem Susam-Saraeva and Eva Spišiaková
Medical translations from Greek Into Arabic and Hebrew / Elaine van Dalen
Translations of Western medical texts in East Asia in the second half of the 19th and early 20th centuries / Ji-Hae Kang
Dissemination of academic medical research through translation throughout history and in contemporary world / Carmen Quijada Diez
Medical terminology and discourse / Joost Buysschaert
Quality, accessibility and readability in medical translation / Wioleta Karwacka
Inter- and intralingual translation of medical information : the importance of comprehensibility / Matilde Nisbeth Brøgger and Karen Korning Zethsen
Machine translation in healthcare / Barry Haddow, Alexandra Birch and Kenneth Heafield
Medical humanities and translation / Vicent Montalt
Knowledge translation / John Ødemark, Gina Fraas Henrichsen and Eivind Engebretsen
Community/liaison interpreting in healthcare settings / Bruce Downing
Child language brokering in healthcare settings / Rachele Antonini and Ira Torresi
Healthcare interpreting ethics : a critical review / Robyn Dean
Remote (telephone) interpreting in healthcare settings / Raquel Lázaro Gutiérrez
Reducing health disparities in the deaf community : the impact of interpreters and the rise of deaf healthcare professionals / Christopher J. Moreland and Laurie Swabey
Translation and interpreting in disaster situations / Patrick Cadwell
Translating global epidemics : the case of Ebola / Tony Joakim Sandset
Interpreter-mediated communication with children in health care settings / Anne Birgitta Nilsen
Disability in translation / Eva Spišiaková
Queer feminisms and the translation of sexual health / Michela Baldo
Translation and women's health / Nesrine Bessaïh
Translation in maternal and neonatal health / Şebnem Susam-Saraeva and Luciana Carvalho Fonseca
Dialogue interpreting in mental healthcare : supportive interference / Hanneke Bot
Nutrition and translation / Renée Desjardins. - PrintBorsay, Anne; Melling, Joseph; Smith, David F.Print
- DigitalLara V. Marcuse, Madeline C. Fields, Jiyeoun (Jenna) Yoo ; foreward, Jacqueline A. French.Contents:
Origin and technical aspects of the EEG
The normal adult EEG
The normal EEG from neonates to adolescents
The abnormal EEG
The EEG and epilepsy
The EEG in other neurological and medical conditions and in status epilepticus
The EEG : tips on indications, reading, and reporting
Influence of common drugs on the EEG and on seizure threshold
Treatment of status epilepticus
Answers.Digital Access ClinicalKey 2016 - DigitalPaul B. Fitzgerald, Z. Jeff Daskalakis.Summary: Repetitive transcranial magnetic stimulation (rTMS) treatment is increasingly a standard part of the management of patients with depression supported by a rapidly expanding research base. This new expanded and amended concise clinical guide will serve as a reference and practical tool for clinicians working with or learning about this treatment technique. The opening chapters provide basic information on the history and development of rTMS treatment and its mechanism of action. Use of the treatment in depression is then addressed in detail, with explanation of the evidence base and discussion of a variety of clinical issues. Side-effects of treatment are explored, and careful consideration is given to the establishment of rTMS treatment programs. There is an updated review of the use of a rTMS applications in other psychiatric conditions such as obsessive-compulsive disorder. New chapters in this edition address the use of deep TMS, theta burst stimulation, accelerated forms of rTMS and what to do in patients not responding to initial therapy. In addition, the various approaches to treatment targeting are addressed in detail. This book will provide the rTMS practitioner or interested generalist an up-to-date and comprehensive understanding of the field as well as provide considerable practical clinical advice.
Contents:
TMS and rTMS: An introduction to the Basic Principles of TMS and rTMS
The History of TMS and rTMS Treatment of Depression
The Mechanism of action of rTMS
Acute rTMS treatment for MDD
Acute rTMS treatment for MDD, clinical indications / patient selection
Practical Issues in Treatment Provision
Switching, Continuing or Ending treatment
The Use of Deep Transcranial Magnetic Stimulation in Depression
Theta Burst Stimulation (TBS) in rTMS Therapy
Accelerated and Intensive rTMS Treatment Protocols
Localization and Targeting of rTMS Treatment of Depression
Treatment Intensity, the Resting Motor Threshold and rTMS Treatment Dosing
Maintenance and Continuation Treatment
rTMS Associated Adverse events, Safety and Monitoring
Side Effects of rTMS Treatment
The Use of rTMS in Other Psychiatric Disorders
Equipment and rTMS Program Set up. - DigitalMinami Matsui, Keng-See Chow, editors.Summary: This book presents the first comprehensive compilation of genome research on the Hevea brasiliensis rubber tree. The genomes of Hevea tree clones (cultivars) are described by three major international groups. Chapters on omics-driven investigations address a broad range of topics including genome annotation and utilisation, transcriptome and gene family analysis, genetic mapping, metabolic pathways in latex and molecular breeding. Additionally, an overview of fundamental rubber biology, especially on laticifers, provides a historical background that is relevant to rubber genome analysis. The book concludes with several perspectives on the future needs of rubber investigations and prospects of rubber genomics. Given the scope of topics, this book will appeal to researchers and university students working in genomics and biotechnology of the rubber tree, and to rubber breeders with an interest in non-conventional approaches to trait analysis, selection and breeding.
Contents:
Intro
Preface to the Series
Preface
Contents
Contributors
Abbreviations
1 Cornucopia that Brazil Gifted the World
Abstract
1.1 Renewable Source of an Industrial Material
1.2 Domestication of the Rubber Tree
1.2.1 From the Forest to the Plantation
1.2.2 Expansion of Rubber Planting
1.3 Extracting Latex and Rubber from a Unique Laticifer Network
1.3.1 Regulation of Latex Flow from the Tapped Tree
1.3.2 The Rubber Component of Latex
1.3.3 Latex and Rubber Regeneration
1.4 Improving Productivity of the Rubber Tree
References 2 The Reyan 7-33-97 Rubber Tree Genome: Insight into Its Structure, Composition and Application
Abstract
2.1 Introduction
2.1.1 Hevea as a Commercial Source of Natural Rubber
2.1.2 Hevea Cultivation and Breeding History in China
2.1.3 Reyan 7-33-97, the Most Popular Hevea Clone Bred in China
2.2 An Overview of the Reyan 7-33-97 Genome
2.2.1 Assessment of Genome Size of the Reyan 7-33-97 Clone
2.2.2 Strategies and Tools for Genome Sequencing and Assembly
2.2.3 Genome Annotation
2.2.4 Gene Family Classification and Phylogenetic Analysis 2.3 Genome-Guided Discovery of Gene Families
2.4 Prospects and Challenges of Genome Sequence Improvement
Acknowledgements
References
3 The RRIM 600 Rubber Tree Genome: Sequencing and Analysis Strategies of a Premier Pedigree Clone
Abstract
3.1 Introduction
3.1.1 It All Started with '22 Seedlings'
3.1.2 Plant Genome Sequencing
3.2 Genome Sequencing Approaches of the Rubber Tree Clone, RRIM 600
3.3 Challenges in Sequencing Plant Genomes: H. Brasiliensis as an Example
3.4 Annotating the H. Brasiliensis Genome
3.5 Genome Database for the Rubber Tree
3.6 Outlook 5.2.2 Development of Microsatellite or Simple Sequence Repeat Markers
5.3 Single Nucleotide Polymorphism (SNP) Discovery in Rubber Tree
5.4 Marker-Trait Association Analyses: QTL Mapping, GWAS and Genomic Selection
5.5 Conclusion
References
6 Genome-Wide Analysis of Transcription Start Sites and Core Promoter Elements in Hevea brasiliensis
Abstract
6.1 Introduction
6.2 How to Obtain TSS Locations and Expression Levels with CAGE Technology
6.3 Genome-Wide Transcription Start Sites in H. brasiliensis
6.3.1 Overview of Tissue-Specific CAGE DataDigital Access Springer 2020 - Digitaleditors, Raphael Rubin, M.D., Professor of Pathology, David S. Strayer, M.D., Ph. D., Professor of Pathology, Department of Pathology and Cell Biology, Jefferson Medical College of Thomas Jefferson University Philadelphia, Pennsylvania ; Founder and Consulting Editor, Emanuel Rubin, M.D., Gonzalo Aponte Distinguished Professor of Pathology, Chairman Emeritus of the Department of Pathology and Cell Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania ; Associate Editors, Jeffrey E. Saffitz, MD, PhD, Mallinckrodt Professor of Medicine, Harvard Medical School, Chairman, Department of Pathology, Beth Israel Deacones Medical Center, Boston, Massachusetts, Alan L. Schiller, MD, Professor and Chairman, Department of Pathology, John A. Burns School of Medicine University of Hawaii, Honolulu, Hawaii.Contents:
Cell adaptation, injury and death
Inflammation
Repair, regeneration and fibrosis
Immunopathology
Neoplasia
Developmental and genetic diseases
Hemodynamic disorders
Environmental and nutritional pathology
Infectious and parasitic diseases
Aging
Systemic autoimmune diseases
Sepsis
Obesity and diabetes mellitus
The pathology of pregnancy
The amyloidoses
Blood vessels
The heart
The respiratory system
The gastroinestinal tract
The liver and biliary system
The pancreas
The kidney
The lower urinary tract and male reproductive system
The female reproductive system and peritoneum
The breast
Hematopathology
The endocrine system
The skin
The head and neck
Bones, joints and soft tissue
Skeletal muscle and peripheral nervous system
The central nervous system
The eye
Forensic pathology.Digital Access LWW Health Library (Medical Education) 2015 - Digitaleditors; David S. Strayer, Jeffrey E. Saffitz and founding editor Emanuel Rubin.Contents:
Sect. I: Mechanisms
Sect. II: Pathogenesis of systemic conditions
Sect. III: Disease of individual organ systems.Digital Access LWW Health Library (Medical Education) 2020 - Digitaleditor-in-chief, Mark W. Kline ; associate editors, Susan Blaney [and 5 others].Contents:
Sect. 1 Foundation in pediatric practice and child health
Sect. 2: Nutrition
Sect. 3: Social-environmental factors
Sect. 4: Newborn
Sect. 5: Principles of adolescent care
Sect. 6: Developmental and behavioral pediatrics
Sect. 7: Pediatric mental health
Sect. 8: Acute and critical illness
Sect. 9: Children with medical complexity
Sect. 10: Palliative care
Sect. 11: Inherited disorders of metabolism
Sect. 12: Clinical genetics and dysmorphology
Sect. 13: Immunological disorders
Sect. 14: Allergic disorders
Sect. 15: Rheumatology
Sect. 16: The musculoskeletal system
Sect. 17: Infectious diseases
Sect. 18: Disorders of the skin
Sect. 19: Disorders of the ear, nose, and the throat
Sect. 20: Disorders fo the oral cavity
Sect. 21: Disorders of the gastrointestinal system
Sect. 22: Disorders of the liver and biliary tract
Sect. 23: Disorders of the blood
Sect. 24: Neoplastic disorders
Sect. 25: Disorders of the kidney and urinary tract
Sect. 26: Disorders of the cardiovascular system
Sect. 27: Disorders of the respiratory system
Sect. 28: Disorders of the endocrine system
Sect. 29: Disorders of the nervous system
Sect. 30: Disorders of the eyes.Digital Access AccessPediatrics 2018 - Digitaleditor, Michael Cabana, MD, MPH, Professor of Pediatrics, Epidemiology, and Biostatistics, Chief, Division of General Pediatrics, Department of Pediatrics, University of California, San Francisco, UCSF Benioff Children's Hospital, Philip R. Lee Institute for Health Policy Studies, San Francisco, California ; consulting editors Hilary M. Haftel, MD, MHPE, Professor of Pediatrics, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, Sunitha V. Kaiser, MD, Assistant Professor of Pediatrics, Department of Pediatrics, University of California, San Francisco, San Francisco, California, Julie Stein O'Brien, MD, Assistant Professor of Pediatrics, Department of Pediatrics, University of California, San Francisco, San Francisco, California.Summary: "The companion review to the most acclaimed book in pediatrics, Rudolph's Pediatrics Self-Assessment & Board Review, delivers more than 1,500 questions focusing on the epidemiology, pathophysiology, presenting symptoms, clinical decision making, therapeutics, and prognosis of different pediatric disorders. The questions and answers are referenced to relevant chapter(s) and pages in Rudolph's Pediatrics, Twenty-Second Edition. More than 300 images, most in full color, to better test visual diagnosis skills"--Provided by publisher.Digital Access AccessPediatrics 2014Users must create a username and password
- DigitalMichael Cabana, Angelo P. Giardino.Digital Access AccessPediatrics 2022Users must create a username and password
- DigitalPaul McCoubrie.Summary: This book gets to the heart of what radiology is and what radiologists do. As a relatively young speciality, there is no guide for radiologists to act as a moral compass. Until now, that is. You will not find any dry technical matters in here. You will not find any clues about how to interpret images better. This book details the 'other 50%': the rest of the working week when a radiologist is not reading scans or performing procedures. The essence of radiology is distilled and offered up to the reader. If you want a comfortable read that offers bland reassurances, look elsewhere. If you want a book that questions everything and discusses uncomfortable truths, this is the book for you. Each of the Rules addresses an important part of professional practice. This book is a manifesto for all radiologists across the globe to raise their game, to be more effective and to serve their patients better.
Contents:
Intro
Preface
Contents
1 Rule #1 / / Obey The Rules
2 Rule #2 / / Smile
3 Rule #3 / / Keep Your Cool
4 Rule #4 / / Work Hard
5 Rule #5 / / Toughen Up
6 Rule #6 / / Respect The Machines
7 Rule #7 / / Never Let A Clinician Play Radiologist
8 Rule #8 / / Forgive The Sins Of The Clinician
9 Rule #9 / / Don't Be Too Approachable
10 Rule #10 / / Be A Good Colleague
11 Rule #11 / / Never Measure Anything
12 Rule #12 / / Never Count Anything
13 Rule #13 / / The Default Is To Say 'Yes'
14 Rule #14 / / Agitation Is Not An Indication 15 Rule #15 / / Always Help The Patient
16 Rule #16 / / Be Damned Careful When Saying An Outright 'No'
17 Rule #17 / / Don't Study Surrogates
18 Rule #18 / / Avoid 'Interesting' Cases
19 Rule #19 / / Beware The 'Fit 90 Year Old'
20 Rule #20 / / Counteract Misjudgement
21 Rule #21 / / There Is No Such Thing As A Radiological Emergency
22 Rule #22 / / If You Feel Resistance, Stop Pushing
23 Rule #23 / / Use Words Carefully
24 Rule #24 / / Brevity Is King
25 Rule #25 / / Ditch The Stethoscope
26 Rule #26 / / CT Is Easy
27 Rule #27 / / Don't Answer The Phone 28 Rule #28 / / Stay Safe The Easy Way
29 Rule #29 / / Get Off The Fence
30 Rule #30 / / Don't Pick Fights
31 Rule #31 / / Beware The 'Good' Case
32 Rule #32 / / Don't Fret About Complications
33 Rule #33 / / We Are Not In The Business Of Exclusion
34 Rule #34 / / Trust Your Clinical Instincts
35 Rule #35 / / If You Have To Fail, Fail Safely
36 Rule #36 / / Take Clinical Details With A Pinch Of Salt
37 Rule #37 / / Don't Crap On Juniors
38 Rule #38 / / Aggressive Clinicians Need Your Help
39 Rule #39 / / Know Loads
40 Rule #40 / / Never Offer To Eat Your Pants 41 Rule #41 / / Radiologists Don't Wear Suede Shoes
42 Rule #42 / / Never Investigate On The Day Of Discharge
43 Rule #43 / / Only Give Clinicians 15 Seconds
44 Rule #44 / / You Can Never Know Too Much Anatomy
45 Rule #45 / / Be Careful With "Limited" Or "Quick" Studies
46 Rule #46 / / Image Quality Is Up To The Radiologist
47 Rule #47 / / It Is Never A Chordoma
48 Rule #48 / / Reporting Rooms Should Be Pitch Black
49 Rule #49 / / Don't Touch The Screens
50 Rule #50 / / Error Is Inherent To Radiology
Appendix
Index - DigitalCanata, Gian Luigi; Jones, Henrique; Krutsch, Werner; Thoreux, Patricia; Vascellari, Alberto.Summary: This book explores running in a broad range of sport disciplines providing a full spectrum coverage on this extremely important and commonly diffused activity. The volume opens with basic information, such as biomechanics, physiology, training principles, nutrition and then presents discipline-specific aspects of running in several individual and team sports. Each chapter is structured organically to offer a uniform and thorough information. For each sport, the authors examine biomechanical, physiological and training specificities as well as injury epidemiology and preventive measures. Filling a gap in literature this book appeals not only to sports physicians, orthopaedic surgeons, trainers, coaches, fellows, and researchers but also to athletes in the various disciplines. Written by experts in the field, this book will be a useful toolkit for all those readers who are seeking a state of the art update on the running athlete.
Contents:
Part 1: General aspects
1 Biomechanics of running
2 Physiology of running-Sprint and short distances
3 Training principles
4 Nutrition For Track Running And Ultrarunning: Practical Recommendations
5 Age and running: children and adolescents, elder people
6 Sex difference between women and men in running
7 Running and metabolic diseases
8 Running activities in times of COVID-19 pandemic
9 Shoes for running
10 Wearable Technology for Long Distance Runners
11 Return to running after Anterior Cruciate Ligament Reconstruction
Part 2: Specific Aspects
12 athletics running disciplines
13 Running in Football
14 Running in rugby
15 Running in gymnastics
16 Running in Tumbling
17 Running in basketball
18 Running in tennis
19 Running in Paddle
20 Running in volleyball
21 Running in handball
22 Running in trail running
23 Running in Ironman triathlon
24 Running in Parkour
25 Running in Field hockey
26 Running in Cycling
27 Running in Alpine skiing
28 Running in Kiteboarding
29 Running in Sailing
30 Running In Rowers
31 Running in Space. - Digital/PrintYoram Groner, Yoshiaki Ito, Paul Liu, James C. Neil, Nancy A. Speck, Andre van Wijnen, editors.
- DigitalBenjamin W. Starnes, Manish Mehta, Frank J. Veith, editors.Contents:
Background- Scope of the Problem
Epidemiology
Pathogenesis
Wall Stress
Clinical Presentation
Diagnostics
Predictors of Certain Death
Pre-Hospital Considerations
Initial Diagnosis and Stabilization in the Emergency Room
Hypotensive Hemostasis
Aortic Occlusion Balloons
Operative Strategies
Randomized Trials- What is the evidence?- Non Randomized Evidence? What is the data telling us?- ICU Management
Post-operative Complications
Outcomes- Early and Late
Guidelines for Transfer to Specialized Centers
Quality of Life after rAAA repair
Coding and Reimbursement for rAAA
Historical Perspectives.- Notes and Illustrations.Digital Access Springer 2017 - DigitalGowri Dorairajan.Summary: The main focus of this book is on ruptured uterus which is a potentially fatal complication during pregnancy. The risk factors and clinical presentation of ruptured uterus vary widely. This book gives an insight into the various possible causes and their presentation. This book aims to sensitize the practicing obstetricians about the need for high level of caution in the deceptive scenarios. The readers would be able to translate the clinical experience and shelf knowledge into every day practice. The cases with similar risks and background will be compiled together under one chapter and at the end of each chapter key points will be highlighted.
Contents:
1. Introduction
2.Rupture of the uterus with a previous caesarean scar
3.Rupture of apparently unscarred uterus
4.Rupture of the uterus weakened due to rare causes
5.Rupture in a Primigravida
6.Rupture of the uterus with a scar due to myomectomy.
7.Rupture due to gestational trophoblastic disease
8.Rupture uterus in Gynaecological situations
9.Management and Complications.Digital Access Springer 2017 - DigitalMonica M. Taylor.Summary: This innovative resource offers a unique, multidisciplinary approach for the utilization of planning theory to eliminate health disparities in rural communities. The book provides tools in the public health, policy, and planning disciplines to help resolve significant differences in life expectancy and quality of life in these communities, concluding with a progressive vision for alleviating geographical health disparities on a local, national, and global scale. Chapters highlight models and approaches best suited to addressing this public health concern, suggesting action strategies focused around each of the three focus areas: 1. Public health: Elucidation of the contextual factors impacting the health of rural communities by: reporting statistical updates on a range of chronic and infectious diseases that disproportionately affect rural populations both globally and in the U.S.; providing discourse on the importance of addressing critical social determinants (global and national) that impede optimal health outcomes among rural populations; and, acknowledging the compositional factors of individuals who reside in rural spaces. 2. Public policy: Application of specific policy models to garner both public and political will towards sustainable policy change to improve healthy living in rural spaces. 3. Rural planning: Identification of national and international planning models that can be used to design strategic plans targeted to improve quality of life, create sustainable development, and establish economic well-being and growth in rural communities. Rural Health Disparities: Public Health, Policy, and Planning Approaches will find an engaged audience among non-profit organizations, planners, public health practitioners, policy analysts, and public interest groups, as well as rural health advocates and students enrolled in planning, public policy, and/or public health courses.
- Digitaleditor-in-chief, Andrew P. Schachat.Contents:
v. 1. Part 1: Retinal imaging and diagnostics / edited by David Sarraf and K. Bailey Freund
Part 2: Basic science and translation to therapy / edited by David R. Hinton
v. 2. Medical retina / edited by Andrew P. Schachat, David Sarraf, and K. Bailey Freund
v. 3. Part 1: Surgical retina / edited by C.P. Wilkinson and Peter Wiedemann
Part 2: Tumors of the retina, choroid, and vitreous / edited by Andrew P. Schachat.Digital Access ClinicalKey 2023
- The R primer. Second edition. — The Real doctor will see you shortly : a physician's first year. First edition [1st ed.]. (171)
- Real life — Renal cancer-- contemporary management. Second edition. (171)
- Renal cancer : current status and innovations — Rhinitis and related upper respiratory conditions : a clinical guide (171)
- Rhino-orbito-cerebral mucormycosis — Ryan's Retina. Seventh edition. (171)
Popular Books
- Harrison's Principles of Internal Medicine
- AAP Red Book Online
- Robbins & Cotran Pathologic Basis of Disease
- Sabiston Textbook of Surgery
- Nelson's Textbook of Pediatrics
- Surgical Exposures in Orthopaedics
- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
- Red Book Online
- ICU Book
- Primary Care Medicine
- Campbell-Walsh Urology
Access restricted to Stanford community
Lane Library Bookmarklet
To install, drag this button to your browser bookmarks or tools bar.
Bookmark on Other Websites
- To Install, Right Click this Button.
- Select "Add to Favorites" (click “Continue” if you see a security alert)
- From the "Create in" menu, select “Favorites Bar” (IE8, IE9) to install
- Once installed it will look like this
- Click "Bookmark on Lane" to bookmark any webpage
- Your saved bookmark will appear on this page
Can't Find It?
Browse by Publisher
Biomedical Publishers
- AccessMedicine
- Springer Protocols
- Books@Ovid
- ClinicalKey
- MyiLibrary
- Stat!Ref
- Lange Series
- National Academy Press
- NCBI Bookshelf
- PsychiatryOnline
- CogNet
- Thieme Atlases
Bioresearch Publishers
- Safari Tech Books
- SpringerLink
- CRCnet base
- MyiLibrary
- ebrary
- EBSCOhost (Choose Research Databases... eBook Collection)
Beyond Stanford
A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.
Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.
MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available. DynaMed is a clinical information resource used to answer questions quickly at the point-of-care. Easy-to-interpret Levels of Evidence help clinicians rapidly determine the quality of the available evidence.Biomedical and pharmacological abstracting and indexing database of published literature, by Elsevier. Embase® contains over 32 million records from over 8,500 currently published journals (1947-present) and is noteworthy for its extensive coverage of the international pharmaceutical and alternative/complementary medicine literature.
Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings. A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS. Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature. A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialties. Provides critical assessments of systematic reviews compiled from a variety of medical journals. Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences.
Includes cited reference searching, citation maps, and an analyze tool.
Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not.
Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.
Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations. PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians. Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration. Provides drug information targeted for patients. A continually updating drug monograph. ECRI Guidelines Trust: A comprehensive database of evidence-based clinical practice guidelines and related documents. MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or products LPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staff Micromedex Lab Advisor: Evidence based laboratory test information Provides patient handouts from the American Academy of Family Physician.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities.
In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.
A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.
Over 10,000 notes outline the status of specific infections within each country.
Provides online, full-text access to Springer's journal titles as well as journals from other publishers.
Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.
Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present. A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.